Small conductance calcium-activated potassium channel protein

Overview


Name	Small conductance calcium-activated potassium channel protein
Smed ID	SMED30012987
Length (bp)	1561

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Small conductance calcium-activated potassium channel protein (SMED30012987) t-SNE clustered cells

Violin plots show distribution of expression levels for Small conductance calcium-activated potassium channel protein (SMED30012987) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012987

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30012987	h1SMcG0014223	SmedASXL_009794	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30012987	h1SMcG0014223	SmedASXL_009794	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
Smed sexual biotype	SMED30012987	h1SMcG0004656	Contig4832	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30012987	h1SMcG0014223	Contig4832	GPL15192	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30012987	h1SMcG0014223	dd_Smed_v6_15108_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30012987	h1SMcG0014223	OX_Smed_1.0.12341	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 186.808 bits (473), Expect = 1.039e-62
Identity = 101/268 (37.69%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  470 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 730

HSP 2 Score: 74.7146 bits (182), Expect = 1.039e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  329 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 445

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 186.808 bits (473), Expect = 1.041e-62
Identity = 100/268 (37.31%), Postives = 165/268 (61.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK       N  +  +     +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  258 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYK-------NTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 518

HSP 2 Score: 74.7146 bits (182), Expect = 1.041e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  117 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 233

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN2 (potassium calcium-activated channel subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:6291])

HSP 1 Score: 186.422 bits (472), Expect = 1.483e-62
Identity = 101/268 (37.69%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  536 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 796

HSP 2 Score: 74.7146 bits (182), Expect = 1.483e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  395 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 511

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN3 (potassium calcium-activated channel subfamily N member 3 [Source:HGNC Symbol;Acc:HGNC:6292])

HSP 1 Score: 190.66 bits (483), Expect = 8.540e-62
Identity = 102/267 (38.20%), Postives = 169/267 (63.30%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VRVCE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   + + I +L DR   +E  +  +   ++ L
Sbjct:  407 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHL 666

HSP 2 Score: 67.781 bits (164), Expect = 8.540e-62
Identity = 48/151 (31.79%), Postives = 84/151 (55.63%), Query Frame = 2

Query:  158 NCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            N     ++A +T   +T      N +KN+          IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  238 NATHNHQHAGTTASSTTFPKA--NKRKNQ---------NIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHP 377

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Match: KCNN3 (potassium calcium-activated channel subfamily N member 3 [Source:HGNC Symbol;Acc:HGNC:6292])

HSP 1 Score: 188.734 bits (478), Expect = 3.798e-61
Identity = 104/282 (36.88%), Postives = 170/282 (60.28%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIE----RPDGIFLMK-------------NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VRVCE      +P G  L                +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   + + I +L DR   +E  +  +   ++ L
Sbjct:  407 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCESPESPAQPSGSSLPAWYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHL 681

HSP 2 Score: 67.3958 bits (163), Expect = 3.798e-61
Identity = 48/151 (31.79%), Postives = 84/151 (55.63%), Query Frame = 2

Query:  158 NCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            N     ++A +T   +T      N +KN+          IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  238 NATHNHQHAGTTASSTTFPKA--NKRKNQ---------NIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHP 377

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 173.326 bits (438), Expect = 1.991e-55
Identity = 93/279 (33.33%), Postives = 169/279 (60.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIE--RPDGIFLMK--NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKD-------RVASIENIMNEISLNIKTLMQI 1464
            L + MF +LY + RVM+LHS +  +  ++S+  +N++NFN RF+LK+ M + P ++++     L     W +R+CE E   PD    +   NS+WL++ITFL VGYGDIVP T CGR +A+++GI G   +++ VA++A+KLE T +E +VH F+  ++L K L+ +AAN+++  W ++K + ++       ++     I   +RK   AIY +R ++R  +++++  V + DV K + N    ++D+         R+ +IE+ +++IS  + +L ++
Sbjct:  365 LSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLV-------EKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQEGLSLRITAIEHQLSDISRELSSLAEL 636

HSP 2 Score: 62.7734 bits (151), Expect = 1.991e-55
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  278 GNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXY-HVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            G RL +R  LH +R+  +D  L FA++GI +MII  ELR + +     SL  +     I T   +   + Y HV ++++FM  N+  D+ VA+S++R  Q+ LE+ IC+L P
Sbjct:  228 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHLLKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCP 339

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 172.94 bits (437), Expect = 2.056e-55
Identity = 93/279 (33.33%), Postives = 169/279 (60.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIE--RPDGIFLMK--NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKD-------RVASIENIMNEISLNIKTLMQI 1464
            L + MF +LY + RVM+LHS +  +  ++S+  +N++NFN RF+LK+ M + P ++++     L     W +R+CE E   PD    +   NS+WL++ITFL VGYGDIVP T CGR +A+++GI G   +++ VA++A+KLE T +E +VH F+  ++L K L+ +AAN+++  W ++K + ++       ++     I   +RK   AIY +R ++R  +++++  V + DV K + N    ++D+         R+ +IE+ +++IS  + +L ++
Sbjct:  449 LSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLV-------EKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQEGLSLRITAIEHQLSDISRELSSLAEL 720

HSP 2 Score: 62.7734 bits (151), Expect = 2.056e-55
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  278 GNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXY-HVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            G RL +R  LH +R+  +D  L FA++GI +MII  ELR + +     SL  +     I T   +   + Y HV ++++FM  N+  D+ VA+S++R  Q+ LE+ IC+L P
Sbjct:  312 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHLLKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCP 423

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 172.94 bits (437), Expect = 2.110e-55
Identity = 93/279 (33.33%), Postives = 169/279 (60.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIE--RPDGIFLMK--NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKD-------RVASIENIMNEISLNIKTLMQI 1464
            L + MF +LY + RVM+LHS +  +  ++S+  +N++NFN RF+LK+ M + P ++++     L     W +R+CE E   PD    +   NS+WL++ITFL VGYGDIVP T CGR +A+++GI G   +++ VA++A+KLE T +E +VH F+  ++L K L+ +AAN+++  W ++K + ++       ++     I   +RK   AIY +R ++R  +++++  V + DV K + N    ++D+         R+ +IE+ +++IS  + +L ++
Sbjct:  345 LSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLV-------EKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQEGLSLRITAIEHQLSDISRELSSLAEL 616

HSP 2 Score: 62.7734 bits (151), Expect = 2.110e-55
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  278 GNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXY-HVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            G RL +R  LH +R+  +D  L FA++GI +MII  ELR + +     SL  +     I T   +   + Y HV ++++FM  N+  D+ VA+S++R  Q+ LE+ IC+L P
Sbjct:  208 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHLLKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCP 319

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 172.94 bits (437), Expect = 2.274e-55
Identity = 93/279 (33.33%), Postives = 169/279 (60.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIE--RPDGIFLMK--NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKD-------RVASIENIMNEISLNIKTLMQI 1464
            L + MF +LY + RVM+LHS +  +  ++S+  +N++NFN RF+LK+ M + P ++++     L     W +R+CE E   PD    +   NS+WL++ITFL VGYGDIVP T CGR +A+++GI G   +++ VA++A+KLE T +E +VH F+  ++L K L+ +AAN+++  W ++K + ++       ++     I   +RK   AIY +R ++R  +++++  V + DV K + N    ++D+         R+ +IE+ +++IS  + +L ++
Sbjct:  338 LSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLV-------EKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQEGLSLRITAIEHQLSDISRELSSLAEL 609

HSP 2 Score: 62.7734 bits (151), Expect = 2.274e-55
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  278 GNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXY-HVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            G RL +R  LH +R+  +D  L FA++GI +MII  ELR + +     SL  +     I T   +   + Y HV ++++FM  N+  D+ VA+S++R  Q+ LE+ IC+L P
Sbjct:  201 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHLLKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCP 312

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Match: kcnl-2 (KCNN (Potassium K ChaNNel, calcium activated)-Like [Source:UniProtKB/TrEMBL;Acc:G5EDA9])

HSP 1 Score: 172.94 bits (437), Expect = 2.311e-55
Identity = 93/279 (33.33%), Postives = 169/279 (60.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIE--RPDGIFLMK--NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKD-------RVASIENIMNEISLNIKTLMQI 1464
            L + MF +LY + RVM+LHS +  +  ++S+  +N++NFN RF+LK+ M + P ++++     L     W +R+CE E   PD    +   NS+WL++ITFL VGYGDIVP T CGR +A+++GI G   +++ VA++A+KLE T +E +VH F+  ++L K L+ +AAN+++  W ++K + ++       ++     I   +RK   AIY +R ++R  +++++  V + DV K + N    ++D+         R+ +IE+ +++IS  + +L ++
Sbjct:  345 LSIMMFFRLYWLCRVMLLHSRVFTDASSRSIAGLNRVNFNARFILKTLMTICPGTMLMIFTAFLWIIAGWILRLCEREYMTPDKYNDINYVNSIWLVAITFLSVGYGDIVPKTNCGRSMAIVTGILGTCASSMVVAVIARKLELTRAEKHVHNFMQDTQLTKQLKHSAANVLRETWFIFKFRKLV-------EKPDFGKIRKHQRKFLLAIYEMRRVRRDQRKLAENLVSLGDVAKTSSNTYELVHDVHSTQEGLSLRITAIEHQLSDISRELSSLAEL 616

HSP 2 Score: 62.7734 bits (151), Expect = 2.311e-55
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  278 GNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXY-HVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            G RL +R  LH +R+  +D  L FA++GI +MII  ELR + +     SL  +     I T   +   + Y HV ++++FM  N+  D+ VA+S++R  Q+ LE+ IC+L P
Sbjct:  208 GGRLIRREILHEKRRHVSDRALAFAIMGIILMIIENELRTAYVIRPGSSLSHLLKFFIIFTTTALLSFVGYFHVIEIQLFMNANAADDWMVALSFRRTCQIGLELLICMLCP 319

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0301953)

HSP 1 Score: 191.43 bits (485), Expect = 2.078e-63
Identity = 105/267 (39.33%), Postives = 168/267 (62.92%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +N+INFN RFVLK+ M + P +++L  +V L    SW +R CE    +    + N+MWLI+ITFL VG+GDIVP T CGR +AV +GI GAG TAL VA++++KLE T +E +VH F++ ++L K L+ AAAN+++  W +YK   +++       R     +   +RK   AIYA+R +K   +++ D +  + D+ K     QN +Y++   ++S ++ + E   N++  MQ
Sbjct:  611 LSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVK-------RVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKT----QNTVYEIISDMSSRQDAIEERLTNLEDKMQ 866

HSP 2 Score: 71.633 bits (174), Expect = 2.078e-63
Identity = 42/113 (37.17%), Postives = 74/113 (65.49%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXX-XXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G RL KR+ L  +RK  +D  L   + GI VM+I  EL  + + + A      ++ L+S+ T+IL+ +++ YH  ++++FMIDN   D+R+A++++R+ Q+ LE+FIC +HP
Sbjct:  468 VGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHP 580

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0344555)

HSP 1 Score: 191.815 bits (486), Expect = 1.473e-62
Identity = 105/267 (39.33%), Postives = 168/267 (62.92%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +N+INFN RFVLK+ M + P +++L  +V L    SW +R CE    +    + N+MWLI+ITFL VG+GDIVP T CGR +AV +GI GAG TAL VA++++KLE T +E +VH F++ ++L K L+ AAAN+++  W +YK   +++       R     +   +RK   AIYA+R +K   +++ D +  + D+ K     QN +Y++   ++S ++ + E   N++  MQ
Sbjct:  208 LSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVK-------RVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKT----QNTVYEIISDMSSRQDAIEERLTNLEDKMQ 463

HSP 2 Score: 68.5514 bits (166), Expect = 1.473e-62
Identity = 43/115 (37.39%), Postives = 74/115 (64.35%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXX-XXXXXXXXXXXXXXXXXXXXXXYHVTDLKV--FMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G RL KR+ L  +RK  +D  L   + GI VM+I  EL  + + + A      ++ L+S+ T+IL+ +++ YH  +++V  FMIDN   D+R+A++++R+ Q+ LE+FIC +HP
Sbjct:   63 VGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHP 177

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0331602)

HSP 1 Score: 191.43 bits (485), Expect = 2.320e-62
Identity = 105/267 (39.33%), Postives = 168/267 (62.92%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +N+INFN RFVLK+ M + P +++L  +V L    SW +R CE    +    + N+MWLI+ITFL VG+GDIVP T CGR +AV +GI GAG TAL VA++++KLE T +E +VH F++ ++L K L+ AAAN+++  W +YK   +++       R     +   +RK   AIYA+R +K   +++ D +  + D+ K     QN +Y++   ++S ++ + E   N++  MQ
Sbjct:  644 LSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVK-------RVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKT----QNTVYEIISDMSSRQDAIEERLTNLEDKMQ 899

HSP 2 Score: 68.1662 bits (165), Expect = 2.320e-62
Identity = 43/115 (37.39%), Postives = 74/115 (64.35%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXX-XXXXXXXXXXXXXXXXXXXXXXYHVTDLKV--FMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G RL KR+ L  +RK  +D  L   + GI VM+I  EL  + + + A      ++ L+S+ T+IL+ +++ YH  +++V  FMIDN   D+R+A++++R+ Q+ LE+FIC +HP
Sbjct:  499 VGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHP 613

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0331603)

HSP 1 Score: 191.43 bits (485), Expect = 2.378e-62
Identity = 105/267 (39.33%), Postives = 168/267 (62.92%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +N+INFN RFVLK+ M + P +++L  +V L    SW +R CE    +    + N+MWLI+ITFL VG+GDIVP T CGR +AV +GI GAG TAL VA++++KLE T +E +VH F++ ++L K L+ AAAN+++  W +YK   +++       R     +   +RK   AIYA+R +K   +++ D +  + D+ K     QN +Y++   ++S ++ + E   N++  MQ
Sbjct:  610 LSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVK-------RVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKT----QNTVYEIISDMSSRQDAIEERLTNLEDKMQ 865

HSP 2 Score: 68.1662 bits (165), Expect = 2.378e-62
Identity = 43/115 (37.39%), Postives = 74/115 (64.35%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXX-XXXXXXXXXXXXXXXXXXXXXXYHVTDLKV--FMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G RL KR+ L  +RK  +D  L   + GI VM+I  EL  + + + A      ++ L+S+ T+IL+ +++ YH  +++V  FMIDN   D+R+A++++R+ Q+ LE+FIC +HP
Sbjct:  465 VGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHP 579

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Match: SK (gene:FBgn0029761 transcript:FBtr0331604)

HSP 1 Score: 191.045 bits (484), Expect = 2.584e-62
Identity = 105/267 (39.33%), Postives = 168/267 (62.92%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +N+INFN RFVLK+ M + P +++L  +V L    SW +R CE    +    + N+MWLI+ITFL VG+GDIVP T CGR +AV +GI GAG TAL VA++++KLE T +E +VH F++ ++L K L+ AAAN+++  W +YK   +++       R     +   +RK   AIYA+R +K   +++ D +  + D+ K     QN +Y++   ++S ++ + E   N++  MQ
Sbjct:  610 LSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVK-------RVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKT----QNTVYEIISDMSSRQDAIEERLTNLEDKMQ 865

HSP 2 Score: 68.1662 bits (165), Expect = 2.584e-62
Identity = 43/115 (37.39%), Postives = 74/115 (64.35%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXX-XXXXXXXXXXXXXXXXXXXXXXYHVTDLKV--FMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G RL KR+ L  +RK  +D  L   + GI VM+I  EL  + + + A      ++ L+S+ T+IL+ +++ YH  +++V  FMIDN   D+R+A++++R+ Q+ LE+FIC +HP
Sbjct:  465 VGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHP 579

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn1a (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a [Source:ZFIN;Acc:ZDB-GENE-070912-703])

HSP 1 Score: 186.422 bits (472), Expect = 2.676e-60
Identity = 103/267 (38.58%), Postives = 168/267 (62.92%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRVCE   ++ +       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++  AAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K     QN +YDL   V+ ++    E+   I TL
Sbjct:  218 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKT----QNVMYDL---VSELQERSEELDKRIGTL 470

HSP 2 Score: 66.2402 bits (160), Expect = 2.676e-60
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T+IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:   77 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHP 188

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn1a (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a [Source:ZFIN;Acc:ZDB-GENE-070912-703])

HSP 1 Score: 187.578 bits (475), Expect = 3.172e-60
Identity = 105/268 (39.18%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++  AAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K     QN +YDL   V+ ++    E+   I TL
Sbjct:  596 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYH-DKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKT----QNVMYDL---VSELQERSEELDKRIGTL 848

HSP 2 Score: 65.4698 bits (158), Expect = 3.172e-60
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T+IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  455 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHP 566

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 185.652 bits (470), Expect = 9.050e-60
Identity = 101/275 (36.73%), Postives = 170/275 (61.82%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W V VCE    D + +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++  AAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K           LQ    +L+ R+  +E  ++ I+ +++ L
Sbjct:  219 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVHVCE-RYHDKVEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELEKRIGHLETKLDSINSSLQAL 485

HSP 2 Score: 65.4698 bits (158), Expect = 9.050e-60
Identity = 44/135 (32.59%), Postives = 75/135 (55.56%), Query Frame = 2

Query:  206 TLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            T   C    KKN+          IG +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T+IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:   64 TQRPCSAPHKKNK---------DIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLCLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIHP 189

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Match: kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:ZFIN;Acc:ZDB-GENE-100921-56])

HSP 1 Score: 189.889 bits (481), Expect = 1.612e-59
Identity = 109/289 (37.72%), Postives = 176/289 (60.90%), Query Frame = 1

Query:  598 SFAPSQLWQWSKCKYDNDERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            S+APSQ       + D D   L + MFL+LYL+ RVM+LHS +  +  ++S+G +NK++FN RFV+K+ M + P +++L   + L    +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +    M   D S+   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   +   + +L DR   +E  M  +   ++ L
Sbjct:  420 SYAPSQ------AEADLDMV-LSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYH-DAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKL----MKKIDHSR---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVMYELMSELNDRSEDLERQMLSLEQRVERL 693

HSP 2 Score: 60.077 bits (144), Expect = 1.612e-59
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++ +R+  + LE+ +  +HP
Sbjct:  293 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVYSKSSMYSLALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELIVSAVHP 404

[Close]

Query:  598 SFAPSQLWQWSKCKYDNDERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            S+APSQ       + D D   L + MFL+LYL+ RVM+LHS +  +  ++S+G +NK++FN RFV+K+ M + P +++L   + L    +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +    M   D S+   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   +   + +L DR   +E  M  +   ++ L
Sbjct:  420 SYAPSQ------AEADLDMV-LSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYH-DAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKL----MKKIDHSR---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVMYELMSELNDRSEDLERQMLSLEQRVERL 693

HSP 2 Score: 60.077 bits (144), Expect = 1.612e-59
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++ +R+  + LE+ +  +HP
Sbjct:  293 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVYSKSSMYSLALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELIVSAVHP 404

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 185.267 bits (469), Expect = 4.732e-62
Identity = 100/268 (37.31%), Postives = 165/268 (61.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK       N  +  +     +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  340 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYK-------NTKLVKKIDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVVLETKLETLI 600

HSP 2 Score: 73.9442 bits (180), Expect = 4.732e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  199 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKGSLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 315

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 185.267 bits (469), Expect = 5.137e-62
Identity = 100/268 (37.31%), Postives = 165/268 (61.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK       N  +  +     +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  419 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYK-------NTKLVKKIDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVVLETKLETLI 679

HSP 2 Score: 73.9442 bits (180), Expect = 5.137e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  278 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKGSLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 394

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: KCNN2 (potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 [Source:NCBI gene;Acc:100145581])

HSP 1 Score: 184.882 bits (468), Expect = 6.320e-62
Identity = 100/268 (37.31%), Postives = 165/268 (61.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK       N  +  +     +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  430 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYK-------NTKLVKKIDHARVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVVLETKLETLI 690

HSP 2 Score: 73.9442 bits (180), Expect = 6.320e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  289 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKGSLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 405

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 190.66 bits (483), Expect = 4.407e-61
Identity = 102/274 (37.23%), Postives = 174/274 (63.50%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRVCE   ++ +       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L+K ++ AAAN+++  W +YK   ++R      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K           LQ    DL+ R+ ++E  ++ ++ ++++L
Sbjct:  257 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETWLIYKHTKLVRK----IDHAK---VRKHQRKFLQAIHLLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLMSELQERNEDLEKRIITLETKIDSLNTSLQSL 523

HSP 2 Score: 65.855 bits (159), Expect = 4.407e-61
Identity = 38/112 (33.93%), Postives = 68/112 (60.71%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  116 VGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIHP 227

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Match: wdr17 (WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-1000178])

HSP 1 Score: 190.66 bits (483), Expect = 4.446e-61
Identity = 102/274 (37.23%), Postives = 174/274 (63.50%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRVCE   ++ +       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L+K ++ AAAN+++  W +YK   ++R      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K           LQ    DL+ R+ ++E  ++ ++ ++++L
Sbjct:  212 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLSKRVKNAAANVLRETWLIYKHTKLVRK----IDHAK---VRKHQRKFLQAIHLLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLMSELQERNEDLEKRIITLETKIDSLNTSLQSL 478

HSP 2 Score: 65.4698 bits (158), Expect = 4.446e-61
Identity = 38/112 (33.93%), Postives = 68/112 (60.71%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:   71 VGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTAILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFITLELTVCAIHP 182

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 186.422 bits (472), Expect = 7.359e-63
Identity = 101/268 (37.69%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  253 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 513

HSP 2 Score: 75.0998 bits (183), Expect = 7.359e-63
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  112 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 228

[Close]

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  253 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 513

HSP 2 Score: 75.0998 bits (183), Expect = 7.359e-63
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  112 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 228

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 [Source:MGI Symbol;Acc:MGI:2153182])

HSP 1 Score: 186.422 bits (472), Expect = 9.256e-63
Identity = 101/268 (37.69%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  518 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 778

HSP 2 Score: 74.7146 bits (182), Expect = 9.256e-63
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  377 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 493

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:MGI Symbol;Acc:MGI:2153183])

HSP 1 Score: 190.66 bits (483), Expect = 6.666e-62
Identity = 102/267 (38.20%), Postives = 169/267 (63.30%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VRVCE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   + + I +L DR   +E  +  +   ++ L
Sbjct:  408 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKK----IDHAK---VRKHQRKFLQAIHQLRGVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHL 667

HSP 2 Score: 67.781 bits (164), Expect = 6.666e-62
Identity = 47/151 (31.13%), Postives = 84/151 (55.63%), Query Frame = 2

Query:  158 NCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            N     ++A +T   +T      N +KN+          IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ T+IL+ ++I YH  ++++F+IDN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  239 NATHNHQHAGTTAGSTTFPKA--NKRKNQ---------NIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHP 378

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Match: Kcnn1 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 [Source:MGI Symbol;Acc:MGI:1933993])

HSP 1 Score: 179.104 bits (453), Expect = 2.353e-57
Identity = 98/274 (35.77%), Postives = 167/274 (60.95%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKK-------INLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS I  +  ++S+G +N++ FN RFV K+ M + P +++L   V      +W VRVCE   ++ +       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++       R         +RK  QAI+ +R +K    +V+D++  + ++ K       +   LQ    +L+ R+A++E+ ++ +  +++ L
Sbjct:  228 LSIPMFLRLYLLARVMLLHSRIFTDASSRSIGALNRVTFNTRFVTKTLMTICPGTVLLVFSVSSWIVAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQGRVRKH-------QRKFLQAIHQLRSVKIEQGKVNDQANTLAELAKAQSIAYEVVSELQAQQEELEARLAALESRLDVLGASLQAL 494

HSP 2 Score: 64.3142 bits (155), Expect = 2.353e-57
Identity = 37/114 (32.46%), Postives = 71/114 (62.28%), Query Frame = 2

Query:  269 TTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
             T+ +RL  RR L  +RK  +D  L F + GI VM+   EL +      ++    ++ L+S+ T+IL+ ++I YH  ++++F++DN   D+R+A++++R+  + LE+ +C +HP
Sbjct:   85 PTVSHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLCSFALKCLISLSTVILLGLVILYHAREIQLFLVDNGADDWRIAMTWERVSLISLELVVCAIHP 198

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BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|Q9H2S1|KCNN2_HUMAN (Small conductance calcium-activated potassium channel protein 2 OS=Homo sapiens OX=9606 GN=KCNN2 PE=1 SV=2)

HSP 1 Score: 186.808 bits (473), Expect = 4.577e-62
Identity = 100/268 (37.31%), Postives = 165/268 (61.57%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK       N  +  +     +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  258 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYK-------NTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 518

HSP 2 Score: 74.7146 bits (182), Expect = 4.577e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  117 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 233

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BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|P70604|KCNN2_RAT (Small conductance calcium-activated potassium channel protein 2 OS=Rattus norvegicus OX=10116 GN=Kcnn2 PE=1 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 5.013e-62
Identity = 101/268 (37.69%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  259 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 519

HSP 2 Score: 74.7146 bits (182), Expect = 5.013e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  118 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 234

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BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|P58390|KCNN2_MOUSE (Small conductance calcium-activated potassium channel protein 2 OS=Mus musculus OX=10090 GN=Kcnn2 PE=1 SV=2)

HSP 1 Score: 186.422 bits (472), Expect = 5.615e-62
Identity = 101/268 (37.69%), Postives = 168/268 (62.69%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  518 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLI 778

HSP 2 Score: 74.7146 bits (182), Expect = 5.615e-62
Identity = 45/117 (38.46%), Postives = 74/117 (63.25%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  +CLEI +C +H  P NY
Sbjct:  377 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNY 493

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BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|P58392|KCNN3_PIG (Small conductance calcium-activated potassium channel protein 3 OS=Sus scrofa OX=9823 GN=KCNN3 PE=2 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 3.601e-61
Identity = 102/267 (38.20%), Postives = 169/267 (63.30%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VRVCE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   + + I +L DR   +E  +  +   ++ L
Sbjct:  400 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHL 659

HSP 2 Score: 67.3958 bits (163), Expect = 3.601e-61
Identity = 48/151 (31.79%), Postives = 84/151 (55.63%), Query Frame = 2

Query:  158 NCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            N     ++A +T   +T      N +KN+          IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  231 NATHNHQHAGTTASSTTFPKA--NKRKNQ---------NIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHP 370

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BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Match: sp|Q9UGI6|KCNN3_HUMAN (Small conductance calcium-activated potassium channel protein 3 OS=Homo sapiens OX=9606 GN=KCNN3 PE=1 SV=2)

HSP 1 Score: 190.66 bits (483), Expect = 3.753e-61
Identity = 102/267 (38.20%), Postives = 169/267 (63.30%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VRVCE   ++ D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   + + I +L DR   +E  +  +   ++ L
Sbjct:  407 LSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHL 666

HSP 2 Score: 67.781 bits (164), Expect = 3.753e-61
Identity = 48/151 (31.79%), Postives = 84/151 (55.63%), Query Frame = 2

Query:  158 NCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            N     ++A +T   +T      N +KN+          IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  238 NATHNHQHAGTTASSTTFPKA--NKRKNQ---------NIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHP 377

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BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A1I8FZC7 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020603g1 PE=4 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 1.098e-69
Identity = 109/265 (41.13%), Postives = 167/265 (63.02%), Query Frame = 1

Query:  667 MGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            + MFL+ YLV RVM+LHS + Q+  +QSLG +N+I+FNFRF+ KS MNLYP  ++  + + L  W SWAVR CE+          NSMW+ +ITFL VGYGDIVP + CGR +AV++G+FG G+TAL VA+LA+KLE + +E YVH F+I  +L+K ++ AAANI+K  W  YK K    +  +          L  +R+L  +I+ IRD++   K+++D SV + ++ +    +  ++  ++ R   +E+ +  I   +  L+Q
Sbjct:  190 LPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGQEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYKYKKAGNTGKT----------LKHQRRLLHSIHRIRDLRGDQKRLADSSVSLTEMHRNQAFMMTSLTTVQSRSREMESRLARIEDKLDRLLQ 444

HSP 2 Score: 81.2629 bits (199), Expect = 1.098e-69
Identity = 52/129 (40.31%), Postives = 80/129 (62.02%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKI-GSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMND 658
            +G RL +R+EL +RRK+ ADL L FA+LGI +MI+  EL  + +         +++ L+SI T IL+  +  YH  D+KVFMIDNS+ D+R+AI+  R   + LE+ +C +HP     GQ+    ++ D
Sbjct:   46 VGARLARRKELFVRRKLIADLSLFFAMLGIVLMIVETELCMANVFNKGQPGSIIVKSLISITTAILLGFITWYHYLDIKVFMIDNSIDDWRLAITMSRGFHLALELLVCAVHPI---PGQHEVQMLVYD 171

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A267GF91 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023081g1 PE=4 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 1.536e-68
Identity = 107/266 (40.23%), Postives = 165/266 (62.03%), Query Frame = 1

Query:  667 MGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGES-ILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
            + MFL+ YLV RVM+LHS + Q+  +QSLG +N+I+FNFRF+ KS MNLYP  ++  + + L  W SWAVR CE+          NSMW+ +ITFL VGYGDIVP + CGR +AV++G+FG G+TAL VA+LA+KLE + +E YVH F+I  +L+K ++ AAANI+K  W  YK           Y R+   +  L  +R+L  +I+ IR+++   K+++D SV + ++ +    +   +  ++ +    +  +  I   +  L+Q
Sbjct:  199 LPMFLRFYLVCRVMMLHSRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYK-----------YKRAGNATKTLKHQRRLLHSIHRIRELRNDQKRLADSSVSLTEMYRNQGFMLTGLASVQAKAKETDAHLQRIEEKLDRLLQ 453

HSP 2 Score: 83.9593 bits (206), Expect = 1.536e-68
Identity = 51/116 (43.97%), Postives = 77/116 (66.38%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLEL----RFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +G RL +R+EL +RRK+ ADL L FA+LGI +MII  EL     F+K G+      +++ L+S+ T IL+  +  YH  D+KVFMIDNS+ D+R+AI+  R   + +E+ +C +HP
Sbjct:   55 VGARLARRKELFVRRKLIADLSLFFAMLGIVMMIIETELCIAGIFNKAGA---GSIVMKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIHP 167

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: R7TTA4 (CaMBD domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_22890 PE=4 SV=1)

HSP 1 Score: 202.986 bits (515), Expect = 1.496e-62
Identity = 110/256 (42.97%), Postives = 163/256 (63.67%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE---IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIEN 1419
              + MFL+L+L+GRV++LHS +  +  +QSLG +N+I+FNF F+ KS M LYP  ++L L++      SW +R CE   I+ P     + N++WLISITFL VGYGDIVP + CGR +AV++GIFGAG TAL VA+LA+KLE + +E YVH F+I  +L+K  +IAAANIVK  W +YK K             K   +L  +RKL +AI+ IRD+K+  +++ D +V + ++ K    L + +  + D    ++ 
Sbjct:  148 FSIPMFLRLFLLGRVIMLHSRLFTDASSQSLGALNRIHFNFSFIFKSMMTLYPEYVLLLLMLSGFVVASWMLRACEMYYIDEPQTRDFL-NALWLISITFLSVGYGDIVPHSYCGRSIAVLTGIFGAGCTALVVAVLARKLELSRAEKYVHNFVIDVELDKRYKIAAANIVKAGWFVYKNK----------KYGKTRRMLVYQRKLLKAIHVIRDVKQEQRRMVDNAVSIVEMHKTQNTLCSLVQGVDDSQVEVDQ 392

HSP 2 Score: 67.781 bits (164), Expect = 1.496e-62
Identity = 38/117 (32.48%), Postives = 71/117 (60.68%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXX----XXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPA 613
            +G RL KR+    RRK+  D  L FA+LGI +MI+  E+  + I +       +  L++  +S+ T  L+  ++ YH+ D+++FM DNS+ D+R+A++ +R+  + +E+ +  +HP 
Sbjct:    2 VGYRLAKRKGFFQRRKVVCDFALAFAILGIVLMIVETEISIAHITNGVAKDNLATLLLKTSISVSTATLLGFVVWYHILDVQLFMCDNSVDDWRLAMNSRRVTSILIELIVYAIHPP 118

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BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A210QBZ8 (Small conductance calcium-activated potassium channel protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT15468 PE=4 SV=1)

HSP 1 Score: 192.586 bits (488), Expect = 3.582e-62
Identity = 103/267 (38.58%), Postives = 162/267 (60.67%), Query Frame = 1

Query:  583 GNFHMSFAPSQLWQWSKCKYDNDERH---------LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKK 1356
            GNFH        + W   KYD  E           L + MFL+LYL+ RVM+LHS +  +  ++S+G +N+I+F+ RFVLK+ M + P +++L  ++ L    SW +R CE    +    + NSMWLISITFL VGYGDIVP T CGR +A+ +G+ GAG TAL VA++A+KLE + +E +VH F++ ++L K ++ AAAN+++  W +YK   +++       +  G  +   +RK  QAI+++R IK G +++ +    + D+ K
Sbjct:  413 GNFH--------FTWYTMKYDGSELLKNVVPVDILLSLPMFLRLYLIARVMLLHSRLFTDASSRSIGALNRISFDTRFVLKTLMTICPGTVMLVFMLSLWIIGSWILRSCEYYHDENHQNILNSMWLISITFLSVGYGDIVPNTYCGRAIAIATGVMGAGCTALVVAVMARKLELSRAEKHVHNFMMDTQLTKRMKNAAANVLRETWLIYKYTKLVK-------KVDGSKVRAHQRKFLQAIHSLRKIKMGQRKLLENQNTLVDMAK 664

HSP 2 Score: 77.0258 bits (188), Expect = 3.582e-62
Identity = 42/127 (33.07%), Postives = 76/127 (59.84%), Query Frame = 2

Query:  233 KKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXX-XXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +K +   ++S    +G RL KR+ L+ RR+  +D CL F + GI +MI+  EL  + +         +   L  L+ +++  +++ YH  ++++F IDN + D+R+AIS+KRL Q+  EI +C++HP
Sbjct:  284 QKQQPETKSSKPNPVGYRLGKRKTLYERRRKISDYCLVFGMGGIVLMIVETELTMANVYLKDHVCSFVLKSLISLSTLILVCLILAYHALEIQLFAIDNCVEDWRIAISWKRLSQLLTEILVCVVHP 410

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BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Match: A0A1I8ITN7 (CaMBD domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 4.251e-62
Identity = 107/269 (39.78%), Postives = 165/269 (61.34%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSW-INQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGES-ILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQ 1461
              + MFL+ YLV RVM+LHS  + Q+  +QSLG +N+I+FNFRF+ KS MNLYP  ++  + + L  W SWAVR CE+          NSMW+ +ITFL VGYGDIVP + CGR +AV++G+FG G+TAL VA+LA+KLE + +E YVH F+I  +L+K ++ AAANI+K  W  YK           Y R+   +  L  +R+L  +I+ IR+++   K+++D SV + ++ +    +   +  ++ +    +  +  I   +  L+Q
Sbjct:  167 FSLPMFLRFYLVCRVMMLHSRRLYQDASSQSLGALNRIHFNFRFIFKSLMNLYPEYVLTVMALFLFIWASWAVRACEMYHGPEHRNFLNSMWMTAITFLTVGYGDIVPASYCGRGIAVLTGLFGTGVTALVVAVLARKLELSRAEKYVHNFVIDIELDKQVKHAAANILKEGWLSYK-----------YKRAGNATKTLKHQRRLLHSIHRIRELRNDQKRLADSSVSLTEMYRNQGFMLTGLASVQAKAKETDAHLQRIEEKLDRLLQ 424

HSP 2 Score: 67.0106 bits (162), Expect = 4.251e-62
Identity = 45/113 (39.82%), Postives = 70/113 (61.95%), Query Frame = 2

Query:  284 RLKKRRELHIRRKICADLCLGFAVLGIFVMIISLEL----RFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            +++   EL   R + ADL L FA+LGI +MII  EL     F+K G+      +++ L+S+ T IL+  +  YH  D+KVFMIDNS+ D+R+AI+  R   + +E+ +C +HP
Sbjct:   28 QMETAAELSCPRPLIADLSLFFAMLGIVMMIIETELCIAGIFNKAGA---GSIVMKSLISVSTAILLGFISWYHYLDIKVFMIDNSMDDWRLAITLSRGFHLAMELLVCAIHP 137

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn2 (potassium calcium-activated channel subfamily N member 2 [Source:ZFIN;Acc:ZDB-GENE-091116-41])

HSP 1 Score: 185.267 bits (469), Expect = 1.060e-63
Identity = 105/295 (35.59%), Postives = 177/295 (60.00%), Query Frame = 1

Query:  583 GNFHMSFAPSQLWQWSKCKYDND-ERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLM 1458
            G +  ++     + ++  K D D +  L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   + L    +W VR CE   +  D       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++AKKLE T +E +VH F++ ++L K ++  AAN+++  W +YK   ++R      D ++   +   +RK  QAI+ +R +K   ++++D++  + D+ K    + + I DL +R    E  +  +   ++TL+
Sbjct:  200 GKYTFTWTARLAFYYTSSKTDADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFTISLWIIAAWTVRACERYHDNQDVTSNFLGAMWLISITFLTIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVAKKLELTKAEKHVHNFMMDTQLTKRVKNTAANVLRETWLIYKNTKLVRK----MDHAR---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANSLVDLAKTQNIMYDLISDLNERGEDTEKRIAVLETKLETLL 487

HSP 2 Score: 78.5666 bits (192), Expect = 1.060e-63
Identity = 44/112 (39.29%), Postives = 74/112 (66.07%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +   G  ++    ++ L+S+ TIIL+ ++I YH  ++++FM+DN+  D+R+A++Y+R+  +CLEI +C +HP
Sbjct:   86 IGQKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYGKESLYSLALKCLISLSTIILLGLIIIYHAREIQLFMVDNAADDWRIAMTYERIFFICLEILVCAIHP 197

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn3 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 [Source:ZFIN;Acc:ZDB-GENE-100921-56])

HSP 1 Score: 187.963 bits (476), Expect = 4.589e-59
Identity = 102/268 (38.06%), Postives = 167/268 (62.31%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+ RVM+LHS +  +  ++S+G +NK++FN RFV+K+ M + P +++L   + L    +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +    M   D S+   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   +   + +L DR   +E  M  +   ++ L
Sbjct:  387 LSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYH-DAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKL----MKKIDHSR---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVMYELMSELNDRSEDLERQMLSLEQRVEQL 646

HSP 2 Score: 60.8474 bits (146), Expect = 4.589e-59
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ TIIL+ ++I YH  ++++F+IDN   D+R+A++ +R+  + LE+ +  +HP
Sbjct:  246 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVYSKSSMYSLALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVHP 357

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn1b (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b [Source:ZFIN;Acc:ZDB-GENE-060503-397])

HSP 1 Score: 143.665 bits (361), Expect = 2.187e-47
Identity = 85/272 (31.25%), Postives = 153/272 (56.25%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRV     P  I  +  ++WL+ + F  +  G  VP      +  ++    GAG TAL VA++A+KLE T +E +VH F++ ++L K ++  AAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K           LQ    +L  R+  +E  ++ I+ +++ L
Sbjct:  219 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVFLFWYPQNILPI--ALWLVYVIFSKLQTGSSVPFWKA--VAFLLQPFRGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELDKRIGQLEEKLDSITSSLQAL 479

HSP 2 Score: 65.855 bits (159), Expect = 2.187e-47
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T+IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:   78 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTLILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERILFIVLELLVCAIHP 189

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: kcnn4 (potassium calcium-activated channel subfamily N member 4 [Source:NCBI gene;Acc:103046778])

HSP 1 Score: 166.777 bits (421), Expect = 2.059e-45
Identity = 90/271 (33.21%), Postives = 156/271 (57.56%), Query Frame = 1

Query:  673 MFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINL-------NLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 1464
            MFL+LYLV R ++LHS +  +   +S+G++N INF FRFVLK  MN YP   +L  I++     +W +R+CE +       M  ++WLI+ITFL VGYGD+ P T+CG++V + +G+ G   TA+ VA++ KKL     E +VH+F++  +++K +R AAAN+++  W L++      +N               +R L +AI   R ++   +++ D +  M D+ K+ +       N  N+  +L+ R+ S+E  ++E+  + ++  Q+
Sbjct:  210 MFLRLYLVHRAILLHSKVLLSASYRSIGSLNNINFTFRFVLKVLMNKYPARTLLVFIMLFWLSAAWMLRLCERQAEVETGDMGTALWLIAITFLTVGYGDVSPCTSCGKVVCLFTGVMGVACTAMLVAVVTKKLALNKGEKHVHFFMMDIQISKEIRNAAANVLRECWLLHRTTQAKNNNGEHRHH---------QRCLLEAIRVFRHLRLKQRKLRDYTSEMVDLSKMQMIMCDLSANWNNSYRELEQRIISMEQKLDELGQSFQSTSQL 471

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Match: KCNQ4 (potassium voltage-gated channel subfamily Q member 4 [Source:NCBI gene;Acc:103034244])

HSP 1 Score: 53.1434 bits (126), Expect = 5.727e-7
Identity = 29/92 (31.52%), Postives = 42/92 (45.65%), Query Frame = 1

Query:  922 NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKA 1197
            +S+W  +IT   +GYGD  P T  GR++A    + G    AL   IL         E +        K  +  R  AAN+++ AW+LY   A
Sbjct:  269 DSLWWGTITLTTIGYGDKTPHTWLGRLLAAGFALLGVSFFALPAGILGSGFALKVQEQH------RQKHFEKRRTPAANLIQAAWRLYSTDA 354

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010066.1 (pep scaffold:Pmarinus_7.0:GL480376:18291:27660:1 gene:ENSPMAG00000009109.1 transcript:ENSPMAT00000010066.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.605 bits (257), Expect = 2.058e-29
Identity = 61/136 (44.85%), Postives = 87/136 (63.97%), Query Frame = 1

Query:  628 SKCKYDNDERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE-IERPDGI---FLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGI 1023
            S  K  + +  L + MFL+LYL+ RVM+LHS +  +  ++S+G +NKI FN RFV+K+ M + P +++L   + L    +W VR CE    P  I   FL   +MWLISITFL +GYGD+VP T CGR V +++GI
Sbjct:   54 SSVKEADVDIVLSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDPQDITSNFL--AAMWLISITFLTIGYGDMVPHTYCGRGVCLLTGI 187

HSP 2 Score: 43.1282 bits (100), Expect = 2.058e-29
Identity = 16/40 (40.00%), Postives = 29/40 (72.50%), Query Frame = 2

Query:  506 KVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLH--PANY 619
            ++F++DN   D+R+A++Y+R+  + LE+ IC +H  P NY
Sbjct:    1 QLFIVDNGADDWRIAMTYQRIFNIGLELLICAIHPIPGNY 40

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001128.1 (pep scaffold:Pmarinus_7.0:GL481044:147302:155278:-1 gene:ENSPMAG00000001003.1 transcript:ENSPMAT00000001128.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 5.509e-6
Identity = 26/92 (28.26%), Postives = 42/92 (45.65%), Query Frame = 1

Query:  922 NSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKA 1197
            +++W  +IT   +GYGD  P+T  GR++A    + G    AL   IL         E +        K  +  R  AA +++ AW+L+   A
Sbjct:  156 DALWWGTITLTTIGYGDKCPVTWVGRLMAASFALLGISFFALPAGILGSGFALKVQEQH------RQKHFEKRRSPAAGLIQAAWRLHSTDA 241

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Match: EDO49636 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFP0])

HSP 1 Score: 54.299 bits (129), Expect = 8.332e-8
Identity = 36/170 (21.18%), Postives = 84/170 (49.41%), Query Frame = 1

Query:  904 GIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRG---------LKQVSDESVVMCDVKKINLNLQNNIY 1386
             I+ +K+++W++ +T   +G+GDIVP++   R +   + I G  + AL ++++ + L+ TN E  +  +I  +   +     AA  ++  W+  +       ++ + D  K + +   + KLF+ +   R ++R          L  V D ++++ DV +   N++  ++
Sbjct:  406 AIYCVKDTVWMMVVTMTTLGFGDIVPVSVVARGLVGFASILGIFLMALFISVVHEYLQLTNQEKRILAYIEKADHQQEKMEKAAACIQSCWRYRQFVKRHMKSLELGDWLKLQRMRFLQHKLFECMRQWRGMRRTWARDDYWRKLFVVDDTAMLLTDVCRSVTNIEKCLH 575

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BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Match: SHAKR8 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIS5])

HSP 1 Score: 50.8322 bits (120), Expect = 7.379e-7
Identity = 22/68 (32.35%), Postives = 40/68 (58.82%), Query Frame = 1

Query:  895 RPDGIFL-MKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKL-EFTNSE 1092
            +PDG+F  + ++ W + +T   VGYGD VP+T  G+++  M  + G    AL   ++A +  +F ++E
Sbjct:  305 QPDGVFSSIPDTAWFVIVTLTNVGYGDAVPVTPIGKLLGTMCALVGVLAIALPSPVIATRFKQFYDAE 372

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn1a (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101164003])

HSP 1 Score: 186.037 bits (471), Expect = 2.707e-60
Identity = 99/274 (36.13%), Postives = 171/274 (62.41%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCE--IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRVCE   ++ +       +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++  AAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K           LQ    +L  R+ ++E+ ++ ++ +++ L
Sbjct:  289 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELDKRIGTLEDKLDSVTGSLQAL 555

HSP 2 Score: 66.6254 bits (161), Expect = 2.707e-60
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T+IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  148 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHP 259

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn1a (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101164003])

HSP 1 Score: 187.193 bits (474), Expect = 2.882e-60
Identity = 101/275 (36.73%), Postives = 171/275 (62.18%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   +      +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++  AAN+++  W +YK   +++      D +K   +   +RK  QAI+ +R +K   ++++D++  + D+ K           LQ    +L  R+ ++E+ ++ ++ +++ L
Sbjct:  679 LSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYH-DKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLCKRVKNTAANVLRETWLIYKHTKLVKK----IDHAK---VRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNVMYDLVSELQERSEELDKRIGTLEDKLDSVTGSLQAL 945

HSP 2 Score: 65.4698 bits (158), Expect = 2.882e-60
Identity = 39/112 (34.82%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+   EL +      +     ++ L+S+ T+IL+ ++I YH  ++++FM+DN   D+R+A++Y+R+  + LE+ +C +HP
Sbjct:  538 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLGLIIMYHAREIQLFMVDNGADDWRIAMTYERIFFIVLELLVCAIHP 649

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn3 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101156116])

HSP 1 Score: 190.274 bits (482), Expect = 1.125e-59
Identity = 109/289 (37.72%), Postives = 176/289 (60.90%), Query Frame = 1

Query:  598 SFAPSQLWQWSKCKYDNDERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            S+APSQ       + D D   L + MFL+LYL+ RVM+LHS +  +  ++S+G +NK++FN RFV+K+ M + P +++L   + L    +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +    M   D S+   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   +   + +L DR   +E  M  +   ++ L
Sbjct:  358 SYAPSQ------AEADLDMV-LSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYH-DAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKL----MKKIDHSR---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVMYELMSELNDRSEDLERQMLSLEQRVEQL 631

HSP 2 Score: 60.4622 bits (145), Expect = 1.125e-59
Identity = 38/112 (33.93%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ T+IL+ ++I YH  ++++F+IDN   D+R+A++ +R+  + LE+ +  +HP
Sbjct:  231 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVYSKSSMYSLALKCLISLSTVILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVHP 342

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: kcnn3 (small conductance calcium-activated potassium channel protein 2 [Source:NCBI gene;Acc:101156116])

HSP 1 Score: 189.889 bits (481), Expect = 1.645e-59
Identity = 109/289 (37.72%), Postives = 176/289 (60.90%), Query Frame = 1

Query:  598 SFAPSQLWQWSKCKYDNDERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKN---SMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            S+APSQ       + D D   L + MFL+LYL+ RVM+LHS +  +  ++S+G +NK++FN RFV+K+ M + P +++L   + L    +W VRVCE    D   +  N   +MWLISITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+KLE T +E +VH F++ ++L K ++ AAAN+++  W +YK   +    M   D S+   +   +RK  QAI+ +R +K   +++SD++  + D+ K+   +   + +L DR   +E  M  +   ++ L
Sbjct:  445 SYAPSQ------AEADLDMV-LSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYH-DAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKL----MKKIDHSR---VRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVMYELMSELNDRSEDLERQMLSLEQRVEQL 718

HSP 2 Score: 60.4622 bits (145), Expect = 1.645e-59
Identity = 38/112 (33.93%), Postives = 69/112 (61.61%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            IG +L  RR L  +RK  +D  L F + GI VM+I  EL +      ++    ++ L+S+ T+IL+ ++I YH  ++++F+IDN   D+R+A++ +R+  + LE+ +  +HP
Sbjct:  318 IGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGVYSKSSMYSLALKCLISLSTVILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELLVSAVHP 429

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Match: KCNN1 (small conductance calcium-activated potassium channel protein 3 [Source:NCBI gene;Acc:101154856])

HSP 1 Score: 189.119 bits (479), Expect = 1.904e-58
Identity = 107/305 (35.08%), Postives = 182/305 (59.67%), Query Frame = 1

Query:  583 GNFHMSFAPSQLWQWSKCKYDND-ERHLGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCW--CSWAVRVCE----IERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKIN-------LNLQNNIYDLKDRVASIENIMNEISLNIKTL 1455
            G +  S+     + ++    D+D +  L + MFL+LYL+GRVM+LHS +  +  ++S+G +NKINFN RFV+K+ M + P +++L   V   CW   +W VR+CE     +     FL   +MWL+SITFL +GYGD+VP T CG+ V +++GI GAG TAL VA++A+K E T +E +VH F++ ++L K ++  AAN+++  W +YK       N  +  +    ++   +RK  QAI+ +R +K   ++++D++  + DV K          +LQ+   +L  RV  +E  ++ + L++++L
Sbjct:  188 GQYVFSWTARLAFNYTSSPSDDDFDIILSVPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSVT--CWIIAAWIVRICERYHDTQEVTSTFL--GAMWLVSITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKSELTRAEKHVHNFMMDTQLLKKIKNTAANVLQETWLIYK-------NTKLVKKIDHATVRHHQRKFLQAIHQLRRVKMEQRKLTDQANTVADVAKTQNMMYDLVSDLQHRSSELDRRVVVLEEKLDSLLLDMQSL 481

HSP 2 Score: 57.3806 bits (137), Expect = 1.904e-58
Identity = 34/112 (30.36%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  275 IGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHP 610
            I  RL  RR L  +RK  +D  L   + GI +M++  EL  +     +     ++ L+S+ T  L+ +++ YH  ++++FM+DN   D+R+A++ +R+  + LE+ +C +HP
Sbjct:   74 ISYRLGLRRALFGKRKQLSDYALVCGMFGIIIMVVETELSRAFYSKESTYSYTLKSLISVSTAFLLGLILMYHAREIQLFMVDNGADDWRIAMTLERILFIALELVVCAIHP 185

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000006262.1 (SMESG000006262.1)

HSP 1 Score: 526.939 bits (1356), Expect = 0.000e+0
Identity = 268/268 (100.00%), Postives = 268/268 (100.00%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 1464
            LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI
Sbjct:  170 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 437

HSP 2 Score: 293.508 bits (750), Expect = 0.000e+0
Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 2

Query:  155 MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 661
            MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI
Sbjct:    1 MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 169

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000006262.1 (SMESG000006262.1)

HSP 1 Score: 526.168 bits (1354), Expect = 0.000e+0
Identity = 268/268 (100.00%), Postives = 268/268 (100.00%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 1464
            LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI
Sbjct:  170 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 437

HSP 2 Score: 292.738 bits (748), Expect = 0.000e+0
Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 2

Query:  155 MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 661
            MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI
Sbjct:    1 MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 169

[Close]

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 1464
            LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI
Sbjct:  172 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 439

HSP 2 Score: 296.59 bits (758), Expect = 0.000e+0
Identity = 171/171 (100.00%), Postives = 171/171 (100.00%), Query Frame = 2

Query:  149 MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 661
            MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI
Sbjct:    1 MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 171

[Close]

BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Match: SMESG000006262.1 (SMESG000006262.1)

HSP 1 Score: 524.242 bits (1349), Expect = 0.000e+0
Identity = 268/268 (100.00%), Postives = 268/268 (100.00%), Query Frame = 1

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 1464
            LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI
Sbjct:  172 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 439

HSP 2 Score: 295.819 bits (756), Expect = 0.000e+0
Identity = 171/171 (100.00%), Postives = 171/171 (100.00%), Query Frame = 2

Query:  149 MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 661
            MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI
Sbjct:    1 MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 171

[Close]

Query:  661 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSXXXXXXXXXXCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 1464
            LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI
Sbjct:  170 LGMGMFLKLYLVGRVMVLHSWINQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAVRVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIFGAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAWKLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSDESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQI 437

HSP 2 Score: 291.967 bits (746), Expect = 0.000e+0
Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 2

Query:  155 MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMXXXXXXXXXXXXXXXXXXXXXXXXYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 661
            MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI
Sbjct:    1 MNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKRRELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLLSILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFICLLHPANYGSGQNANMTMMNDI 169

The following BLAST results are available for this feature:

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Yeast
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNN2	1.039e-62	37.69	potassium calcium-activated channel subfamily N me...	[more]
KCNN2	1.041e-62	37.31	potassium calcium-activated channel subfamily N me...	[more]
KCNN2	1.483e-62	37.69	potassium calcium-activated channel subfamily N me...	[more]
KCNN3	8.540e-62	38.20	potassium calcium-activated channel subfamily N me...	[more]
KCNN3	3.798e-61	36.88	potassium calcium-activated channel subfamily N me...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnl-2	1.991e-55	33.33	KCNN (Potassium K ChaNNel, calcium activated)-Like...	[more]
kcnl-2	2.056e-55	33.33	KCNN (Potassium K ChaNNel, calcium activated)-Like...	[more]
kcnl-2	2.110e-55	33.33	KCNN (Potassium K ChaNNel, calcium activated)-Like...	[more]
kcnl-2	2.274e-55	33.33	KCNN (Potassium K ChaNNel, calcium activated)-Like...	[more]
kcnl-2	2.311e-55	33.33	KCNN (Potassium K ChaNNel, calcium activated)-Like...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SK	2.078e-63	39.33	gene:FBgn0029761 transcript:FBtr0301953	[more]
SK	1.473e-62	39.33	gene:FBgn0029761 transcript:FBtr0344555	[more]
SK	2.320e-62	39.33	gene:FBgn0029761 transcript:FBtr0331602	[more]
SK	2.378e-62	39.33	gene:FBgn0029761 transcript:FBtr0331603	[more]
SK	2.584e-62	39.33	gene:FBgn0029761 transcript:FBtr0331604	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnn1a	2.676e-60	38.58	potassium intermediate/small conductance calcium-a...	[more]
kcnn1a	3.172e-60	39.18	potassium intermediate/small conductance calcium-a...	[more]
kcnn1b	9.050e-60	36.73	potassium intermediate/small conductance calcium-a...	[more]
kcnn3	1.612e-59	37.72	potassium intermediate/small conductance calcium-a...	[more]
kcnn3	1.612e-59	37.72	potassium intermediate/small conductance calcium-a...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNN2	4.732e-62	37.31	potassium channel, calcium activated intermediate/...	[more]
KCNN2	5.137e-62	37.31	potassium channel, calcium activated intermediate/...	[more]
KCNN2	6.320e-62	37.31	potassium channel, calcium activated intermediate/...	[more]
wdr17	4.407e-61	37.23	WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10...	[more]
wdr17	4.446e-61	37.23	WD repeat domain 17 [Source:Xenbase;Acc:XB-GENE-10...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kcnn2	7.359e-63	37.69	potassium intermediate/small conductance calcium-a...	[more]
Kcnn2	7.359e-63	37.69	potassium intermediate/small conductance calcium-a...	[more]
Kcnn2	9.256e-63	37.69	potassium intermediate/small conductance calcium-a...	[more]
Kcnn3	6.666e-62	38.20	potassium intermediate/small conductance calcium-a...	[more]
Kcnn1	2.353e-57	35.77	potassium intermediate/small conductance calcium-a...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9H2S1\|KCNN2_HUMAN	4.577e-62	37.31	Small conductance calcium-activated potassium chan...	[more]
sp\|P70604\|KCNN2_RAT	5.013e-62	37.69	Small conductance calcium-activated potassium chan...	[more]
sp\|P58390\|KCNN2_MOUSE	5.615e-62	37.69	Small conductance calcium-activated potassium chan...	[more]
sp\|P58392\|KCNN3_PIG	3.601e-61	38.20	Small conductance calcium-activated potassium chan...	[more]
sp\|Q9UGI6\|KCNN3_HUMAN	3.753e-61	38.20	Small conductance calcium-activated potassium chan...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8FZC7	1.098e-69	41.13	CaMBD domain-containing protein OS=Macrostomum lig...	[more]
A0A267GF91	1.536e-68	40.23	CaMBD domain-containing protein OS=Macrostomum lig...	[more]
R7TTA4	1.496e-62	42.97	CaMBD domain-containing protein (Fragment) OS=Capi...	[more]
A0A210QBZ8	3.582e-62	38.58	Small conductance calcium-activated potassium chan...	[more]
A0A1I8ITN7	4.251e-62	39.78	CaMBD domain-containing protein OS=Macrostomum lig...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnn2	1.060e-63	35.59	potassium calcium-activated channel subfamily N me...	[more]
kcnn3	4.589e-59	38.06	potassium intermediate/small conductance calcium-a...	[more]
kcnn1b	2.187e-47	31.25	potassium intermediate/small conductance calcium-a...	[more]
kcnn4	2.059e-45	33.21	potassium calcium-activated channel subfamily N me...	[more]
KCNQ4	5.727e-7	31.52	potassium voltage-gated channel subfamily Q member...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000010066.1	2.058e-29	44.85	pep scaffold:Pmarinus_7.0:GL480376:18291:27660:1 g...	[more]
ENSPMAT00000001128.1	5.509e-6	28.26	pep scaffold:Pmarinus_7.0:GL481044:147302:155278:-...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO49636	8.332e-8	21.18	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAKR8	7.379e-7	32.35	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnn1a	2.707e-60	36.13	small conductance calcium-activated potassium chan...	[more]
kcnn1a	2.882e-60	36.73	small conductance calcium-activated potassium chan...	[more]
kcnn3	1.125e-59	37.72	small conductance calcium-activated potassium chan...	[more]
kcnn3	1.645e-59	37.72	small conductance calcium-activated potassium chan...	[more]
KCNN1	1.904e-58	35.08	small conductance calcium-activated potassium chan...	[more]

BLAST of Small conductance calcium-activated potassium channel protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000006262.1	0.000e+0	100.00	SMESG000006262.1	[more]
SMESG000006262.1	0.000e+0	100.00	SMESG000006262.1	[more]
SMESG000006262.1	0.000e+0	100.00	SMESG000006262.1	[more]
SMESG000006262.1	0.000e+0	100.00	SMESG000006262.1	[more]
SMESG000006262.1	0.000e+0	100.00	SMESG000006262.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence
protein sequence

transcript sequence

>SMED30012987 ID=SMED30012987|Name=Small conductance calcium-activated potassium channel protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1561bp
AACAAATATACAAAGCTCTTAACAATGCTTATTTTAAATTTACTATTGTA
GCTTTTCTTCGTAATATTCATAACGTTTCGAACAGTAAATCCTAATTTTC
ACATTTATTCTCCCATTGAAATTGACAAGTGCCAGATTTACATTCGACAT
GTCAATGAATTGTGAAAGTGCAGAAGAGAATGCCAACTCTACGAATCTTG
ATTCCACATTGAATGATTGCATTGATAATTTTAAAAAGAATGAATTTCGA
CGAAGAGCTTCCTCAATAACGACGATTGGAAATCGTTTGAAGAAAAGACG
GGAATTGCACATAAGACGGAAAATCTGCGCAGATCTTTGTTTGGGTTTTG
CAGTTTTGGGTATATTTGTTATGATTATCAGTTTGGAATTAAGATTTTCT
AAAATCGGGAGCATGGCAATCTCTCTACAGCTCATACAATTGTTATTGAG
CATTCTGACGATCATCTTGGTTGCCATTTTGATAACTTATCACGTAACTG
ATCTGAAAGTGTTCATGATTGACAATTCACTCTCAGATTTCCGAGTTGCG
ATAAGTTATAAACGGCTCGGACAAGTATGCTTGGAAATTTTCATATGTCT
TTTGCACCCAGCCAATTATGGCAGTGGTCAAAATGCAAATATGACAATGA
TGAACGACATTTGGGTATGGGAATGTTCCTAAAACTGTATTTGGTTGGCA
GAGTCATGGTTCTTCATAGTTGGATAAATCAAAATCTTTGGACACAGAGT
TTAGGAACAATGAATAAAATAAATTTTAATTTCAGATTTGTTCTTAAATC
CGCGATGAATTTGTATCCAGTTAGCATAATTCTTTTTCTGATCGTAATTC
TTCTGTGTTGGTGTAGTTGGGCGGTAAGAGTTTGTGAAATTGAAAGGCCG
GACGGGATATTTTTGATGAAAAATAGTATGTGGTTAATTTCAATAACATT
TCTTGGGGTTGGTTACGGAGACATTGTTCCTTTGACGACATGTGGACGCA
TAGTTGCTGTCATGTCAGGAATTTTTGGAGCTGGAATCACAGCTTTGACA
GTGGCGATTTTGGCGAAAAAATTGGAATTTACAAATTCCGAAAGCTATGT
ACATTATTTTATAATTAGTTCCAAATTAAACAAATCTCTGAGAATAGCTG
CAGCTAACATTGTGAAACGTGCATGGAAGCTGTATAAAATCAAGGCAATA
ATCAGATCAAACATGTCAATGTATGATCGAAGCAAAGGTGAGTCCATATT
GTGCTGTGAAAGGAAATTGTTTCAGGCCATTTATGCGATCAGGGACATCA
AGAGGGGGCTGAAACAAGTCAGCGACGAATCAGTTGTAATGTGTGATGTG
AAAAAGATAAATCTAAATCTTCAAAATAATATTTACGATTTGAAAGACCG
AGTCGCTTCAATAGAAAATATAATGAATGAAATAAGCTTGAACATAAAAA
CACTGATGCAAATAAATAAAGTGAAAAATAAATGAAAAAAATAATTTAAC
AAAAATACTTAATTGGTTTTTGACATTATTTGATAAATAAATAATTTTCT
TTAAAAAAAAA

protein sequence of SMED30012987-orf-1

>SMED30012987-orf-1 ID=SMED30012987-orf-1|Name=SMED30012987-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=303bp
MLGNFHMSFAPSQLWQWSKCKYDNDERHLGMGMFLKLYLVGRVMVLHSWI
NQNLWTQSLGTMNKINFNFRFVLKSAMNLYPVSIILFLIVILLCWCSWAV
RVCEIERPDGIFLMKNSMWLISITFLGVGYGDIVPLTTCGRIVAVMSGIF
GAGITALTVAILAKKLEFTNSESYVHYFIISSKLNKSLRIAAANIVKRAW
KLYKIKAIIRSNMSMYDRSKGESILCCERKLFQAIYAIRDIKRGLKQVSD
ESVVMCDVKKINLNLQNNIYDLKDRVASIENIMNEISLNIKTLMQINKVK
NK*

protein sequence of SMED30012987-orf-2

>SMED30012987-orf-2 ID=SMED30012987-orf-2|Name=SMED30012987-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=145bp
MATKMIVRMLNNNCMSCREIAMLPILENLNSKLIIITNIPKTAKPKQRSA
QIFRLMCNSRLFFKRFPIVVIEEALRRNSFFLKLSMQSFNVESRFVELAF
SSALSQFIDMSNVNLALVNFNGRINVKIRIYCSKRYEYYEEKLQ*

protein sequence of SMED30012987-orf-3

>SMED30012987-orf-3 ID=SMED30012987-orf-3|Name=SMED30012987-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=178bp
MSMNCESAEENANSTNLDSTLNDCIDNFKKNEFRRRASSITTIGNRLKKR
RELHIRRKICADLCLGFAVLGIFVMIISLELRFSKIGSMAISLQLIQLLL
SILTIILVAILITYHVTDLKVFMIDNSLSDFRVAISYKRLGQVCLEIFIC
LLHPANYGSGQNANMTMMNDIWVWECS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head
PLANA:0000420	parapharyngeal region

Vocabulary: **INTERPRO**
Term	Definition
IPR013099	K_chnl_dom
IPR004178	CaM-bd_dom
IPR015449	K_chnl_Ca-activ_SK

Vocabulary: **molecular function**
Term	Definition
GO:0005516	calmodulin binding
GO:0015269	calcium-activated potassium channel activity
GO:0016286	small conductance calcium-activated potassium channel activity

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0043025	neuronal cell body

Vocabulary: **biological process**
Term	Definition
GO:0006813	potassium ion transport
GO:0006810	transport
GO:0006811	ion transport
GO:0071805	potassium ion transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR015449	Potassium channel, calcium-activated, SK	PFAM	PF03530	SK_channel	coord: 46..155 e-value: 7.5E-27 score: 93.6
IPR015449	Potassium channel, calcium-activated, SK	PANTHER	PTHR10153	SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL	coord: 37..177
None	No IPR available	TMHMM	TMhelix		coord: 59..81
None	No IPR available	TMHMM	TMhelix		coord: 91..113

Main menu

Small conductance calcium-activated potassium channel protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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