slit-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012984 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of slit-2 vs. Ensembl Human
Match: SLIT2 (slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]) HSP 1 Score: 84.3445 bits (207), Expect = 3.562e-16 Identity = 84/254 (33.07%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 413 DLACPEKCR---CEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCYLAWLGEWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 622 HSP 2 Score: 70.0922 bits (170), Expect = 9.339e-12 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I EI L++ TI I AFS L+ +DLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 190 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETIT-------------------------EIRLEQNTIK-----VIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 416
BLAST of slit-2 vs. Ensembl Human
Match: SLIT2 (slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]) HSP 1 Score: 84.3445 bits (207), Expect = 3.845e-16 Identity = 84/254 (33.07%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 495 DLACPEKCR---CEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCYLAWLGEWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 704 HSP 2 Score: 70.0922 bits (170), Expect = 1.013e-11 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I EI L++ TI I AFS L+ +DLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 272 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETIT-------------------------EIRLEQNTIK-----VIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 498 HSP 3 Score: 51.6026 bits (122), Expect = 4.935e-6 Identity = 63/252 (25.00%), Postives = 109/252 (43.25%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRL-LFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C + + C L +P N PR +++ L+ N R+T T+ + L+ L + +++IE AF L L+ L L+ N L LF + L L L N+ + + +FRG V +++L + + + + + + L L L +N + LS F+ + + L L +N C C L WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 28 CPAQC---SCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNIT--RITKTDFAGLRH----LRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD-LEVLTLNNNNITRLSVASFNHMPK-LRTFRLHSNNLYCDCHLAWLSDWLRQR-------PRVGLYT----QCMGPSHLRGHNVAEVQKREFVC 257
BLAST of slit-2 vs. Ensembl Human
Match: SLIT2 (slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]) HSP 1 Score: 83.9593 bits (206), Expect = 3.884e-16 Identity = 84/254 (33.07%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 503 DLACPEKCR---CEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCYLAWLGEWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 712 HSP 2 Score: 72.4034 bits (176), Expect = 1.759e-12 Identity = 73/280 (26.07%), Postives = 117/280 (41.79%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I EI L++ TI I AFS L+ +DLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C IP + K++ + A+++C
Sbjct: 272 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETIT-------------------------EIRLEQNTIK-----VIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLAC 506 HSP 3 Score: 51.6026 bits (122), Expect = 5.067e-6 Identity = 63/252 (25.00%), Postives = 109/252 (43.25%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRL-LFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C + + C L +P N PR +++ L+ N R+T T+ + L+ L + +++IE AF L L+ L L+ N L LF + L L L N+ + + +FRG V +++L + + + + + + L L L +N + LS F+ + + L L +N C C L WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 28 CPAQC---SCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNIT--RITKTDFAGLRH----LRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD-LEVLTLNNNNITRLSVASFNHMPK-LRTFRLHSNNLYCDCHLAWLSDWLRQR-------PRVGLYT----QCMGPSHLRGHNVAEVQKREFVC 257
BLAST of slit-2 vs. Ensembl Human
Match: SLIT2 (slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]) HSP 1 Score: 83.9593 bits (206), Expect = 3.893e-16 Identity = 84/254 (33.07%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 507 DLACPEKCR---CEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCYLAWLGEWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 716 HSP 2 Score: 72.4034 bits (176), Expect = 1.970e-12 Identity = 73/280 (26.07%), Postives = 117/280 (41.79%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I EI L++ TI I AFS L+ +DLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C IP + K++ + A+++C
Sbjct: 276 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETIT-------------------------EIRLEQNTIK-----VIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLAC 510 HSP 3 Score: 51.6026 bits (122), Expect = 4.988e-6 Identity = 63/252 (25.00%), Postives = 109/252 (43.25%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRL-LFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C + + C L +P N PR +++ L+ N R+T T+ + L+ L + +++IE AF L L+ L L+ N L LF + L L L N+ + + +FRG V +++L + + + + + + L L L +N + LS F+ + + L L +N C C L WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 28 CPAQC---SCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNIT--RITKTDFAGLRH----LRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD-LEVLTLNNNNITRLSVASFNHMPK-LRTFRLHSNNLYCDCHLAWLSDWLRQR-------PRVGLYT----QCMGPSHLRGHNVAEVQKREFVC 257
BLAST of slit-2 vs. Ensembl Human
Match: SLIT2 (slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]) HSP 1 Score: 83.9593 bits (206), Expect = 3.949e-16 Identity = 84/254 (33.07%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 499 DLACPEKCR---CEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCYLAWLGEWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 708 HSP 2 Score: 69.707 bits (169), Expect = 1.040e-11 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I EI L++ TI I AFS L+ +DLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 276 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETIT-------------------------EIRLEQNTIK-----VIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 502 HSP 3 Score: 51.2174 bits (121), Expect = 5.377e-6 Identity = 63/252 (25.00%), Postives = 109/252 (43.25%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRL-LFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C + + C L +P N PR +++ L+ N R+T T+ + L+ L + +++IE AF L L+ L L+ N L LF + L L L N+ + + +FRG V +++L + + + + + + L L L +N + LS F+ + + L L +N C C L WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 28 CPAQC---SCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNIT--RITKTDFAGLRH----LRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD-LEVLTLNNNNITRLSVASFNHMPK-LRTFRLHSNNLYCDCHLAWLSDWLRQR-------PRVGLYT----QCMGPSHLRGHNVAEVQKREFVC 257
BLAST of slit-2 vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6]) HSP 1 Score: 68.1662 bits (165), Expect = 1.434e-11 Identity = 78/275 (28.36%), Postives = 123/275 (44.73%), Query Frame = 1
Query: 187 KDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFK-SLSLKTLVLDSNRNLQLAKDSFRG-LVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEI 1005
+ + CP C C + C L ++P N P ++ L + +T + + S + LK L + + + +I +++FS L++LQ+L LS NR+ + N F+ +L L L L N ++ +G ++ L++ H+ L + I L L L NRL + FR LD L NNP+NC C+L+W+ L+ + VC P NL+GSSIE L C + +R K T E TAEI
Sbjct: 13 ESATCPAEC---VCVDRTVSCVGQQLTEVPQNIPNDTIRLDLQDN-----EITKIGPNDFSSL-MNLKALQLMDNQIVTIHNQSFSSLVFLQKLRLSRNRIRHLPDNVFQNNLKLTHLDLSENDITVVSDAQLQGPEFLEVLNLDKNHIFCLENNVISSWVS-LEVLTLNGNRLTTFEEPSNARFRQLD---LFNNPWNCDCRLRWMRKWLEKAEGQNKT------------VCATPLNLQGSSIEILQDKFMTCSGNRKRR--YKKTCE-TAEI 259 HSP 2 Score: 55.0694 bits (131), Expect = 1.655e-7 Identity = 72/252 (28.57%), Postives = 97/252 (38.49%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLA-LTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
CP C C T + C GL +P N P P T EI L++ IS SI S +F +L L LDLS N + I P F L +L TLVL N L D+F GL L + + + L+ L+L DN ++ +S L L+L NP C C L+WLA + LQ + + CE PK L+ L F+C+
Sbjct: 260 CPLPC---TCTGTTVDCRDSGLTYVPTNLP---------------PSTT----------EIRLEQNQIS-----SIPSHSFKNLKNLTRLDLSKNIITEIQPKAFLGLHNLHTLVLYGNNITDLKSDTFEGLGSLQLLLLNANQLTCIRRGTFDHVPKLSMLSLYDNDIKSISEVTFQNLTSLSTLHLAKNPLICDCNLQWLAQINLQKN------------IETSGARCEQPKRLRKKKFATLPPNKFKCK 466
BLAST of slit-2 vs. Ensembl Celegans
Match: lron-9 (ELRR (Extracellular Leucine-Rich Repeat) ONly [Source:UniProtKB/TrEMBL;Acc:O02329]) HSP 1 Score: 56.9954 bits (136), Expect = 3.128e-8 Identity = 52/211 (24.64%), Postives = 96/211 (45.50%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS--LKTLVLDSN-------------RNLQLAKDSFRGLV---------VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNP-VCEYPKNLKGSSIENLSIVSFQ 942
L +L+++ ++ +E + F L L+ELDL N + I + FK L+ LKT+ L +N L LA+ F + ++ L + C++ + + + L LNL N+L+ L N L +++L++ +NP+ C +L ++ R K+ + + + TN VC+ P L+G I + + FQ
Sbjct: 306 LTRLSLAGNFISKLEPDVFFGLSSLEELDLGWNEIKTIPTDVFKPLTDKLKTISLRNNPISELPSTGLGMLEKLSLAECGFTSISADQLKDYPKLEELDLSKCNISNIVENTFENQKDSLKKLNLQKNKLKSLPNLIKNL-PAIESLDVSSNPYRCDGELVNFVFGVEDRVKKAEENGNSFFVANTNETVCDRPYTLRGEQILQVEVEKFQ 515
BLAST of slit-2 vs. Ensembl Celegans
Match: lron-9 (ELRR (Extracellular Leucine-Rich Repeat) ONly [Source:UniProtKB/TrEMBL;Acc:O02329]) HSP 1 Score: 56.9954 bits (136), Expect = 3.128e-8 Identity = 52/211 (24.64%), Postives = 96/211 (45.50%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS--LKTLVLDSN-------------RNLQLAKDSFRGLV---------VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNP-VCEYPKNLKGSSIENLSIVSFQ 942
L +L+++ ++ +E + F L L+ELDL N + I + FK L+ LKT+ L +N L LA+ F + ++ L + C++ + + + L LNL N+L+ L N L +++L++ +NP+ C +L ++ R K+ + + + TN VC+ P L+G I + + FQ
Sbjct: 306 LTRLSLAGNFISKLEPDVFFGLSSLEELDLGWNEIKTIPTDVFKPLTDKLKTISLRNNPISELPSTGLGMLEKLSLAECGFTSISADQLKDYPKLEELDLSKCNISNIVENTFENQKDSLKKLNLQKNKLKSLPNLIKNL-PAIESLDVSSNPYRCDGELVNFVFGVEDRVKKAEENGNSFFVANTNETVCDRPYTLRGEQILQVEVEKFQ 515
BLAST of slit-2 vs. Ensembl Celegans
Match: lron-9 (ELRR (Extracellular Leucine-Rich Repeat) ONly [Source:UniProtKB/TrEMBL;Acc:O02329]) HSP 1 Score: 56.6102 bits (135), Expect = 3.455e-8 Identity = 52/211 (24.64%), Postives = 96/211 (45.50%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS--LKTLVLDSN-------------RNLQLAKDSFRGLV---------VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNP-VCEYPKNLKGSSIENLSIVSFQ 942
L +L+++ ++ +E + F L L+ELDL N + I + FK L+ LKT+ L +N L LA+ F + ++ L + C++ + + + L LNL N+L+ L N L +++L++ +NP+ C +L ++ R K+ + + + TN VC+ P L+G I + + FQ
Sbjct: 306 LTRLSLAGNFISKLEPDVFFGLSSLEELDLGWNEIKTIPTDVFKPLTDKLKTISLRNNPISELPSTGLGMLEKLSLAECGFTSISADQLKDYPKLEELDLSKCNISNIVENTFENQKDSLKKLNLQKNKLKSLPNLIKNL-PAIESLDVSSNPYRCDGELVNFVFGVEDRVKKAEENGNSFFVANTNETVCDRPYTLRGEQILQVEVEKFQ 515
BLAST of slit-2 vs. Ensembl Celegans
Match: lron-11 (ELRR (Extracellular Leucine-Rich Repeat) ONly [Source:UniProtKB/TrEMBL;Acc:A0A078BS18]) HSP 1 Score: 54.6842 bits (130), Expect = 1.421e-7 Identity = 60/210 (28.57%), Postives = 94/210 (44.76%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGL-VVQSLSMKDC-HLKILTHESIKQISGY-----------------------LTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSF 939
LK L +S + IE A L L+ L+L++N+L+ + NT+ +LKTL L SN + L SF GL +Q L++ +LK + + Q+S L+ L+L++N L Y++ L + + NL+L NN ++CSC L+ L + K C P+NL G+ I LS S
Sbjct: 215 LKHLDVSENLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNTWSLPALKTLDLSSNLFVSLETASFDGLPALQYLNISHSRNLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPIPPLSHLDLSNNELRYVAPGM-LQWPNIRNLHLANNDWHCSCDLRVSNLNPRDDAK-----------------CSGPENLAGAPINELSSCSI 406
BLAST of slit-2 vs. Ensembl Fly
Match: kek3 (gene:FBgn0028370 transcript:FBtr0300848) HSP 1 Score: 83.1889 bits (204), Expect = 2.920e-16 Identity = 91/298 (30.54%), Postives = 127/298 (42.62%), Query Frame = 1
Query: 193 SECPELCNQGACKLTM----LLCETPGLLQIPMNPPRGIQKVILS-NQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS-LKTLVLDSNRNLQLAKDSFRGLVVQ--SLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWL-ALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTS----EITAEISCISDDMSNSQVKW 1047
+ECP +C CK +LC L IP G Q + LS N+ L P ++ ++ + L+K+ ++ C L IE AF LI L ELDLS N L I +S L+ L L N L++ D+F G V Q L + DC L + + + L L L NRL + + L L L N +NCSC L+ L A LQ N P P CE P L G + + L + F C +P++ D IT +SC + + VKW
Sbjct: 77 AECPAVCE---CKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQLIPDDSFAT-----AQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAF-GHVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWMLQ------QNIPSG-----IPPTCESPPRLSGRAWDKLDVDDFAC-VPQIVATDTTAHGVEGRNIT--MSCYVEGVPQPAVKW 351
BLAST of slit-2 vs. Ensembl Fly
Match: kek3 (gene:FBgn0028370 transcript:FBtr0080752) HSP 1 Score: 83.1889 bits (204), Expect = 2.920e-16 Identity = 91/298 (30.54%), Postives = 127/298 (42.62%), Query Frame = 1
Query: 193 SECPELCNQGACKLTM----LLCETPGLLQIPMNPPRGIQKVILS-NQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS-LKTLVLDSNRNLQLAKDSFRGLVVQ--SLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWL-ALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTS----EITAEISCISDDMSNSQVKW 1047
+ECP +C CK +LC L IP G Q + LS N+ L P ++ ++ + L+K+ ++ C L IE AF LI L ELDLS N L I +S L+ L L N L++ D+F G V Q L + DC L + + + L L L NRL + + L L L N +NCSC L+ L A LQ N P P CE P L G + + L + F C +P++ D IT +SC + + VKW
Sbjct: 77 AECPAVCE---CKWKSGKESVLCLNANLTHIPQPLDAGTQLLDLSGNEIQLIPDDSFAT-----AQLLNLQKVYLARCHLRLIERHAFRKLINLVELDLSQNLLSAIPSLALYHVSELRELRLSGNPILRVPDDAF-GHVPQLVKLELSDCRLSHIAVRAFAGLESSLEWLKLDGNRLSEVRSGTITSLASLHGLELARNTWNCSCSLRPLRAWMLQ------QNIPSG-----IPPTCESPPRLSGRAWDKLDVDDFAC-VPQIVATDTTAHGVEGRNIT--MSCYVEGVPQPAVKW 351
BLAST of slit-2 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330730) HSP 1 Score: 72.4034 bits (176), Expect = 8.419e-13 Identity = 71/254 (27.95%), Postives = 115/254 (45.28%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYL-SNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
++ CP +C +C + C GL +P ++++ L N + T+ R L+ L +++ + +IE +F L+ L+ LD+S+N + + FK SL++L LD+N+ L + +F+GLV L+ILT L +N L L N F L R L L L +NPF C C L WL+ L++ T+ L T C+ P LKG ++ +L F+C
Sbjct: 70 EARCPRVC---SCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTV--IYETDFQRL----TKLRMLQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLV---------ELEILT---------------LNNNNLTSLPHNIFGGLGR-LRALRLSDNPFACDCHLSWLSRFLRSATR---------LAPYTR--CQSPSQLKGQNVADLHDQEFKC 278 HSP 2 Score: 66.6254 bits (161), Expect = 5.144e-11 Identity = 66/254 (25.98%), Postives = 107/254 (42.13%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS-LKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLE-YLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
DS+CP +C+ C+ T + C GL +IP + P +++L++ L R S+ + F L +L +L+L N+L I PN F+ S ++ L L N+ +++ F GL H+ L TLNL DN++ + F+ L L +LNL +NPFNC+C L W A L+ ++ L C P ++ I++L F+C
Sbjct: 516 DSDCPAMCH---CEGTTVDCTGRGLKEIPRDIPLHTTELLLND----------NELGRISSDGL-------------------FGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGL----------------HQ--------LKTLNLYDNQISCVMPGSFEHL-NSLTSLNLASNPFNCNCHLAWFAEWLRKKS-----------LNGGAARCGAPSKVRDVQIKDLPHSEFKC 701 HSP 3 Score: 53.1434 bits (126), Expect = 7.618e-7 Identity = 68/278 (24.46%), Postives = 117/278 (42.09%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFL--YPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVL-DSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSND-FDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
++ CP C C ++ C L +P+ P ++ L QNF+ P ++++ R L+++ +SN +++ I +A S L L L L N++ + FK L L+L ++N + KD+FR L SL DN ++ L+N FD + + + ++L NPF C C L+WLA L + + CE PK + IE+L F+C +L+ +K++ E + C
Sbjct: 292 ENSCPHPCR---CADGIVDCREKSLTSVPVTLPDDTTELRLE-QNFITELPPKSFSSFRR-------LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSL------------------------YDNNIQSLANGTFDAM-KSIKTVHLAKNPFICDCNLRWLADYLHKNP-----------IETSGARCESPKRMHRRRIESLREEKFKCSWDELR---MKLSGECRMDSDC 519
BLAST of slit-2 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330729) HSP 1 Score: 72.4034 bits (176), Expect = 8.957e-13 Identity = 71/254 (27.95%), Postives = 115/254 (45.28%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYL-SNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
++ CP +C +C + C GL +P ++++ L N + T+ R L+ L +++ + +IE +F L+ L+ LD+S+N + + FK SL++L LD+N+ L + +F+GLV L+ILT L +N L L N F L R L L L +NPF C C L WL+ L++ T+ L T C+ P LKG ++ +L F+C
Sbjct: 70 EARCPRVC---SCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTV--IYETDFQRL----TKLRMLQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLV---------ELEILT---------------LNNNNLTSLPHNIFGGLGR-LRALRLSDNPFACDCHLSWLSRFLRSATR---------LAPYTR--CQSPSQLKGQNVADLHDQEFKC 278 HSP 2 Score: 66.6254 bits (161), Expect = 4.978e-11 Identity = 66/254 (25.98%), Postives = 107/254 (42.13%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS-LKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLE-YLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
DS+CP +C+ C+ T + C GL +IP + P +++L++ L R S+ + F L +L +L+L N+L I PN F+ S ++ L L N+ +++ F GL H+ L TLNL DN++ + F+ L L +LNL +NPFNC+C L W A L+ ++ L C P ++ I++L F+C
Sbjct: 516 DSDCPAMCH---CEGTTVDCTGRGLKEIPRDIPLHTTELLLND----------NELGRISSDGL-------------------FGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGL----------------HQ--------LKTLNLYDNQISCVMPGSFEHL-NSLTSLNLASNPFNCNCHLAWFAEWLRKKS-----------LNGGAARCGAPSKVRDVQIKDLPHSEFKC 701 HSP 3 Score: 53.1434 bits (126), Expect = 8.307e-7 Identity = 68/278 (24.46%), Postives = 117/278 (42.09%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFL--YPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVL-DSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSND-FDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
++ CP C C ++ C L +P+ P ++ L QNF+ P ++++ R L+++ +SN +++ I +A S L L L L N++ + FK L L+L ++N + KD+FR L SL DN ++ L+N FD + + + ++L NPF C C L+WLA L + + CE PK + IE+L F+C +L+ +K++ E + C
Sbjct: 292 ENSCPHPCR---CADGIVDCREKSLTSVPVTLPDDTTELRLE-QNFITELPPKSFSSFRR-------LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSL------------------------YDNNIQSLANGTFDAM-KSIKTVHLAKNPFICDCNLRWLADYLHKNP-----------IETSGARCESPKRMHRRRIESLREEKFKCSWDELR---MKLSGECRMDSDC 519
BLAST of slit-2 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330732) HSP 1 Score: 72.4034 bits (176), Expect = 8.957e-13 Identity = 71/254 (27.95%), Postives = 115/254 (45.28%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYL-SNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
++ CP +C +C + C GL +P ++++ L N + T+ R L+ L +++ + +IE +F L+ L+ LD+S+N + + FK SL++L LD+N+ L + +F+GLV L+ILT L +N L L N F L R L L L +NPF C C L WL+ L++ T+ L T C+ P LKG ++ +L F+C
Sbjct: 70 EARCPRVC---SCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTV--IYETDFQRL----TKLRMLQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLV---------ELEILT---------------LNNNNLTSLPHNIFGGLGR-LRALRLSDNPFACDCHLSWLSRFLRSATR---------LAPYTR--CQSPSQLKGQNVADLHDQEFKC 278 HSP 2 Score: 66.6254 bits (161), Expect = 4.978e-11 Identity = 66/254 (25.98%), Postives = 107/254 (42.13%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS-LKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLE-YLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
DS+CP +C+ C+ T + C GL +IP + P +++L++ L R S+ + F L +L +L+L N+L I PN F+ S ++ L L N+ +++ F GL H+ L TLNL DN++ + F+ L L +LNL +NPFNC+C L W A L+ ++ L C P ++ I++L F+C
Sbjct: 516 DSDCPAMCH---CEGTTVDCTGRGLKEIPRDIPLHTTELLLND----------NELGRISSDGL-------------------FGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGL----------------HQ--------LKTLNLYDNQISCVMPGSFEHL-NSLTSLNLASNPFNCNCHLAWFAEWLRKKS-----------LNGGAARCGAPSKVRDVQIKDLPHSEFKC 701 HSP 3 Score: 53.1434 bits (126), Expect = 8.307e-7 Identity = 68/278 (24.46%), Postives = 117/278 (42.09%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFL--YPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVL-DSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSND-FDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
++ CP C C ++ C L +P+ P ++ L QNF+ P ++++ R L+++ +SN +++ I +A S L L L L N++ + FK L L+L ++N + KD+FR L SL DN ++ L+N FD + + + ++L NPF C C L+WLA L + + CE PK + IE+L F+C +L+ +K++ E + C
Sbjct: 292 ENSCPHPCR---CADGIVDCREKSLTSVPVTLPDDTTELRLE-QNFITELPPKSFSSFRR-------LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSL------------------------YDNNIQSLANGTFDAM-KSIKTVHLAKNPFICDCNLRWLADYLHKNP-----------IETSGARCESPKRMHRRRIESLREEKFKCSWDELR---MKLSGECRMDSDC 519
BLAST of slit-2 vs. Ensembl Zebrafish
Match: lrrc4cb (leucine rich repeat containing 4C, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-080327-5]) HSP 1 Score: 82.8037 bits (203), Expect = 3.832e-16 Identity = 72/248 (29.03%), Postives = 112/248 (45.16%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKW 1047
LK+L + N + SI S+AFS L L+ LDL RL +I F+ LS L L + N+ + SF+GLV +Q L M ++ + S + L LNLA N L +L +D L ++L +NP+NC+C + WL+ L R+ P ++ C P +LKG I L FQC P + +D+ +T + AE+ C ++ +++ V W
Sbjct: 151 LKELWLRNNPIESIPSDAFSRLPSLRRLDLGELKRLSYISSGAFQGLSNLRYLNLGMCNLKEVPNIQPLIRLDELEMSGNQLTVIQPSSFKGLVHLQKLWMMHAQVQTIERNSFDDLHS-LRELNLAHNNLTFLPHDLYTPLHHLQRVHLHHNPWNCNCDILWLSWWL------RETVPTNTSCCAR---CNSPPSLKGRYIGELDQSYFQCYAPVIIEPPVDLNLTEGMAAELKCRTNSVTS--VSW 386
BLAST of slit-2 vs. Ensembl Zebrafish
Match: lrrc4cb (leucine rich repeat containing 4C, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-080327-5]) HSP 1 Score: 82.8037 bits (203), Expect = 3.832e-16 Identity = 72/248 (29.03%), Postives = 112/248 (45.16%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKW 1047
LK+L + N + SI S+AFS L L+ LDL RL +I F+ LS L L + N+ + SF+GLV +Q L M ++ + S + L LNLA N L +L +D L ++L +NP+NC+C + WL+ L R+ P ++ C P +LKG I L FQC P + +D+ +T + AE+ C ++ +++ V W
Sbjct: 151 LKELWLRNNPIESIPSDAFSRLPSLRRLDLGELKRLSYISSGAFQGLSNLRYLNLGMCNLKEVPNIQPLIRLDELEMSGNQLTVIQPSSFKGLVHLQKLWMMHAQVQTIERNSFDDLHS-LRELNLAHNNLTFLPHDLYTPLHHLQRVHLHHNPWNCNCDILWLSWWL------RETVPTNTSCCAR---CNSPPSLKGRYIGELDQSYFQCYAPVIIEPPVDLNLTEGMAAELKCRTNSVTS--VSW 386
BLAST of slit-2 vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 78.9518 bits (193), Expect = 9.118e-15 Identity = 80/255 (31.37%), Postives = 115/255 (45.10%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE F + EL L+SNRL ++ + K L L+TL+L SNR + SF GL L L+L DN + +S FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 486 DLACPEKCR---CEGTTVDCSGQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSMLKGLGGLRTLMLRSNRISCVNNGSFTGLSSVRL------------------------LSLYDNLITSMSPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGEWL--RKKR---------IVTGNPRCQSPYFLKEIPIQDVAVQDFACE 696 HSP 2 Score: 74.7146 bits (182), Expect = 2.150e-13 Identity = 76/274 (27.74%), Postives = 122/274 (44.53%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
+CPELC C ++ C GL +IP N P I ++ L QN S+ I + AF+ L+ +DLS+N++ + ++F+ L SL +LVL N+ +L K F GL L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C ++ K+ + A+++C
Sbjct: 263 QCPELC---TCSNNVVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKITELPKGLFDGLFSLQLLLLNANKINCLRVDSFQDLQN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFMCDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCS--GVEDYRSKLGGDCFADLAC 489
BLAST of slit-2 vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 78.9518 bits (193), Expect = 9.242e-15 Identity = 80/255 (31.37%), Postives = 115/255 (45.10%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE F + EL L+SNRL ++ + K L L+TL+L SNR + SF GL L L+L DN + +S FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 486 DLACPEKCR---CEGTTVDCSGQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSMLKGLGGLRTLMLRSNRISCVNNGSFTGLSSVRL------------------------LSLYDNLITSMSPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGEWL--RKKR---------IVTGNPRCQSPYFLKEIPIQDVAVQDFACE 696 HSP 2 Score: 74.3294 bits (181), Expect = 2.587e-13 Identity = 76/274 (27.74%), Postives = 122/274 (44.53%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
+CPELC C ++ C GL +IP N P I ++ L QN S+ I + AF+ L+ +DLS+N++ + ++F+ L SL +LVL N+ +L K F GL L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C ++ K+ + A+++C
Sbjct: 263 QCPELC---TCSNNVVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKITELPKGLFDGLFSLQLLLLNANKINCLRVDSFQDLQN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFMCDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCS--GVEDYRSKLGGDCFADLAC 489
BLAST of slit-2 vs. Ensembl Zebrafish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 78.9518 bits (193), Expect = 9.262e-15 Identity = 80/255 (31.37%), Postives = 115/255 (45.10%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE F + EL L+SNRL ++ + K L L+TL+L SNR + SF GL L L+L DN + +S FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 486 DLACPEKCR---CEGTTVDCSGQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSMLKGLGGLRTLMLRSNRISCVNNGSFTGLSSVRL------------------------LSLYDNLITSMSPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGEWL--RKKR---------IVTGNPRCQSPYFLKEIPIQDVAVQDFACE 696 HSP 2 Score: 74.7146 bits (182), Expect = 2.222e-13 Identity = 76/274 (27.74%), Postives = 122/274 (44.53%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
+CPELC C ++ C GL +IP N P I ++ L QN S+ I + AF+ L+ +DLS+N++ + ++F+ L SL +LVL N+ +L K F GL L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C ++ K+ + A+++C
Sbjct: 263 QCPELC---TCSNNVVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKITELPKGLFDGLFSLQLLLLNANKINCLRVDSFQDLQN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFMCDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCS--GVEDYRSKLGGDCFADLAC 489
BLAST of slit-2 vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 83.9593 bits (206), Expect = 4.590e-16 Identity = 83/254 (32.68%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE AF + EL L+SNR+ + FK L LKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 518 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGAFEGANGVNELLLTSNRMENVRHKMFKGLEGLKTLMLRSNRISCVNNDSFTGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGDWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 727 HSP 2 Score: 69.707 bits (169), Expect = 1.043e-11 Identity = 75/286 (26.22%), Postives = 119/286 (41.61%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDI------KVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ +DLS+N++ I + F+ L SL +LVL N+ +L K F GLV+ L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA L T + + C P+ L I + F+C IP + + K++ + A+++C
Sbjct: 281 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEMRLE-QN-----------------------------SIKVIPPGAFSPYKKLRRIDLSNNQISEIAADAFQGLRSLNSLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHN-LNLLSLYDNKLQTIAKGTFAPLRAIQTLHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAQEQYFIPGIHHLGCTEDYRSKLSGDCFADLAC 521
BLAST of slit-2 vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 83.5741 bits (205), Expect = 4.671e-16 Identity = 83/254 (32.68%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE AF + EL L+SNR+ + FK L LKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 518 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGAFEGANGVNELLLTSNRMENVRHKMFKGLEGLKTLMLRSNRISCVNNDSFTGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGDWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 727 HSP 2 Score: 69.707 bits (169), Expect = 1.026e-11 Identity = 75/286 (26.22%), Postives = 119/286 (41.61%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDI------KVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ +DLS+N++ I + F+ L SL +LVL N+ +L K F GLV+ L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA L T + + C P+ L I + F+C IP + + K++ + A+++C
Sbjct: 281 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEMRLE-QN-----------------------------SIKVIPPGAFSPYKKLRRIDLSNNQISEIAADAFQGLRSLNSLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHN-LNLLSLYDNKLQTIAKGTFAPLRAIQTLHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAQEQYFIPGIHHLGCTEDYRSKLSGDCFADLAC 521
BLAST of slit-2 vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 83.5741 bits (205), Expect = 4.761e-16 Identity = 83/254 (32.68%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE AF + EL L+SNR+ + FK L LKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 518 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGAFEGANGVNELLLTSNRMENVRHKMFKGLEGLKTLMLRSNRISCVNNDSFTGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGDWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 727 HSP 2 Score: 69.707 bits (169), Expect = 1.054e-11 Identity = 75/286 (26.22%), Postives = 119/286 (41.61%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDI------KVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ +DLS+N++ I + F+ L SL +LVL N+ +L K F GLV+ L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA L T + + C P+ L I + F+C IP + + K++ + A+++C
Sbjct: 281 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEMRLE-QN-----------------------------SIKVIPPGAFSPYKKLRRIDLSNNQISEIAADAFQGLRSLNSLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHN-LNLLSLYDNKLQTIAKGTFAPLRAIQTLHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAQEQYFIPGIHHLGCTEDYRSKLSGDCFADLAC 521
BLAST of slit-2 vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 83.5741 bits (205), Expect = 5.092e-16 Identity = 83/254 (32.68%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE AF + EL L+SNR+ + FK L LKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 480 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGAFEGANGVNELLLTSNRMENVRHKMFKGLEGLKTLMLRSNRISCVNNDSFTGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGDWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 689 HSP 2 Score: 70.0922 bits (170), Expect = 9.334e-12 Identity = 74/274 (27.01%), Postives = 117/274 (42.70%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ +DLS+N++ I + F+ L SL +LVL N+ +L K F GLV+ L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 257 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEMRLE-QN-----------------------------SIKVIPPGAFSPYKKLRRIDLSNNQISEIAADAFQGLRSLNSLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHN-LNLLSLYDNKLQTIAKGTFAPLRAIQTLHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 483
BLAST of slit-2 vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 83.5741 bits (205), Expect = 5.226e-16 Identity = 83/254 (32.68%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE AF + EL L+SNR+ + FK L LKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 518 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGAFEGANGVNELLLTSNRMENVRHKMFKGLEGLKTLMLRSNRISCVNNDSFTGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGDWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 727 HSP 2 Score: 69.3218 bits (168), Expect = 1.280e-11 Identity = 75/286 (26.22%), Postives = 119/286 (41.61%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDI------KVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ +DLS+N++ I + F+ L SL +LVL N+ +L K F GLV+ L + + + + L +S + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA L T + + C P+ L I + F+C IP + + K++ + A+++C
Sbjct: 281 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEMRLE-QN-----------------------------SIKVIPPGAFSPYKKLRRIDLSNNQISEIAADAFQGLRSLNSLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHN-LNLLSLYDNKLQTIAKGTFAPLRAIQTLHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAQEQYFIPGIHHLGCTEDYRSKLSGDCFADLAC 521
BLAST of slit-2 vs. Ensembl Mouse
Match: Slit2 (slit guidance ligand 2 [Source:MGI Symbol;Acc:MGI:1315205]) HSP 1 Score: 86.2705 bits (212), Expect = 3.920e-17 Identity = 84/254 (33.07%), Postives = 117/254 (46.06%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 495 DLACPEKCR---CEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGL------------------------GSVRLLSLYDNQITTVAPGAFDSL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 704 HSP 2 Score: 72.7886 bits (177), Expect = 7.824e-13 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 272 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 498 HSP 3 Score: 50.0618 bits (118), Expect = 8.397e-6 Identity = 62/252 (24.60%), Postives = 108/252 (42.86%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRL-LFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C + + C L +P N PR +++ L+ N R+T + + L+ L + +++IE AF L L+ L L+ N L LF + L L L N+ + + +FRG V +++L + + + + + + L L L +N + LS F+ + + L L +N C C L WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 28 CPAQC---SCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNIT--RITKIDFAGLRH----LRVLQLMENRISTIERGAFQDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD-LEVLTLNNNNITRLSVASFNHMPK-LRTFRLHSNNLYCDCHLAWLSDWLRQR-------PRVGLY----TQCMGPSHLRGHNVAEVQKREFVC 257
BLAST of slit-2 vs. Ensembl Mouse
Match: Slit2 (slit guidance ligand 2 [Source:MGI Symbol;Acc:MGI:1315205]) HSP 1 Score: 85.8853 bits (211), Expect = 8.390e-17 Identity = 84/254 (33.07%), Postives = 117/254 (46.06%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 507 DLACPEKCR---CEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGL------------------------GSVRLLSLYDNQITTVAPGAFDSL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 716 HSP 2 Score: 74.3294 bits (181), Expect = 2.711e-13 Identity = 73/280 (26.07%), Postives = 117/280 (41.79%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C IP + K++ + A+++C
Sbjct: 276 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLAC 510
BLAST of slit-2 vs. Ensembl Mouse
Match: Slit2 (slit guidance ligand 2 [Source:MGI Symbol;Acc:MGI:1315205]) HSP 1 Score: 85.8853 bits (211), Expect = 8.504e-17 Identity = 84/254 (33.07%), Postives = 117/254 (46.06%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 495 DLACPEKCR---CEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGL------------------------GSVRLLSLYDNQITTVAPGAFDSL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 704 HSP 2 Score: 72.0182 bits (175), Expect = 1.469e-12 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 272 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 498
BLAST of slit-2 vs. Ensembl Mouse
Match: Slit2 (slit guidance ligand 2 [Source:MGI Symbol;Acc:MGI:1315205]) HSP 1 Score: 85.5001 bits (210), Expect = 8.964e-17 Identity = 84/254 (33.07%), Postives = 117/254 (46.06%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 499 DLACPEKCR---CEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGL------------------------GSVRLLSLYDNQITTVAPGAFDSL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 708 HSP 2 Score: 72.0182 bits (175), Expect = 1.548e-12 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 276 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 502
BLAST of slit-2 vs. Ensembl Mouse
Match: Slit2 (slit guidance ligand 2 [Source:MGI Symbol;Acc:MGI:1315205]) HSP 1 Score: 85.5001 bits (210), Expect = 9.055e-17 Identity = 84/254 (33.07%), Postives = 117/254 (46.06%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 507 DLACPEKCR---CEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGL------------------------GSVRLLSLYDNQITTVAPGAFDSL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 716 HSP 2 Score: 74.3294 bits (181), Expect = 2.900e-13 Identity = 73/280 (26.07%), Postives = 117/280 (41.79%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C IP + K++ + A+++C
Sbjct: 276 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLAC 510
BLAST of slit-2 vs. UniProt/SwissProt
Match: sp|Q9WVC1|SLIT2_RAT (Slit homolog 2 protein (Fragment) OS=Rattus norvegicus OX=10116 GN=Slit2 PE=1 SV=3) HSP 1 Score: 88.1965 bits (217), Expect = 7.758e-17 Identity = 81/253 (32.02%), Postives = 115/253 (45.45%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 499 DLACPEKCR---CEGTTVDCSNQKLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINLSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFTGL------------------------GSVRLLSLYDNQITTVAPGAFGTLHSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 708 HSP 2 Score: 71.2478 bits (173), Expect = 1.398e-11 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 276 HCPIAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 502
BLAST of slit-2 vs. UniProt/SwissProt
Match: sp|Q9R1B9|SLIT2_MOUSE (Slit homolog 2 protein OS=Mus musculus OX=10090 GN=Slit2 PE=2 SV=2) HSP 1 Score: 85.8853 bits (211), Expect = 5.948e-16 Identity = 84/254 (33.07%), Postives = 117/254 (46.06%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL G + L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 495 DLACPEKCR---CEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGL------------------------GSVRLLSLYDNQITTVAPGAFDSL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 704 HSP 2 Score: 72.0182 bits (175), Expect = 1.028e-11 Identity = 72/274 (26.28%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ LDLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C + R K++ + A+++C
Sbjct: 272 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLSGDCFADLAC 498
BLAST of slit-2 vs. UniProt/SwissProt
Match: sp|O94813|SLIT2_HUMAN (Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1) HSP 1 Score: 83.9593 bits (206), Expect = 1.865e-15 Identity = 84/254 (33.07%), Postives = 116/254 (45.67%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ SN +T IE AF + E+ L+SNRL + FK L SLKTL+L SNR + DSF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++I F C
Sbjct: 503 DLACPEKCR---CEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTV--LEATGIFKKLPQ---LRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL------------------------LSLYDNQITTVAPGAFDTL-HSLSTLNLLANPFNCNCYLAWLGEWL--RKKR---------IVTGNPRCQKPYFLKEIPIQDVAIQDFTC 712 HSP 2 Score: 72.4034 bits (176), Expect = 8.445e-12 Identity = 73/280 (26.07%), Postives = 117/280 (41.79%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
CP C C ++ C GL +IP N P I EI L++ TI I AFS L+ +DLS+N++ + P+ F+ L SL +LVL N+ +L K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + ++L NPF C C LKWLA L T + + C P+ L I + F+C IP + K++ + A+++C
Sbjct: 272 HCPAAC---TCSNNIVDCRGKGLTEIPTNLPETIT-------------------------EIRLEQNTIK-----VIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNP-----------IETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADLAC 506
BLAST of slit-2 vs. UniProt/SwissProt
Match: sp|O88279|SLIT1_RAT (Slit homolog 1 protein OS=Rattus norvegicus OX=10116 GN=Slit1 PE=1 SV=1) HSP 1 Score: 79.337 bits (194), Expect = 5.741e-14 Identity = 74/257 (28.79%), Postives = 117/257 (45.53%), Query Frame = 1
Query: 184 TKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
T D CP C C+ +++ C L +IP P+ ++ L+N L T L + S LKK+ +SN ++ IE F + EL L++N+L + F+ L L+TL+L +NR + DSF GL V+ LS+ D H+ ++ + FD L + L LNL NPFNC+CQL WL L+ R + NP C+ P L+ +++++ F+C+
Sbjct: 508 TSDVACPHKCR---CEASVVECSGLKLSKIPERIPQSTTELRLNNNEISI--LEATGLFKKLSH---LKKINLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGA------------------------FDTL-QALSTLNLLANPFNCNCQLAWLGDWLRKRK-----------IVTGNPRCQNPDFLRQIPLQDVAFPDFRCE 720 HSP 2 Score: 75.0998 bits (183), Expect = 1.149e-12 Identity = 73/281 (25.98%), Postives = 119/281 (42.35%), Query Frame = 1
Query: 193 SECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
CP +C +C ++ C GL IP N P + ++ RL + SI AFS L+ +DLS+N++ I P+ F+ L SL +LVL N+ L + F GL L + + + + + ++ + + L+ L+L DN+++ L+ R + L+L NPF C C LKWLA L+T + T C P+ L I + F+C IP + D + SE T++++C
Sbjct: 280 GSCPAMC---SCSNGIVDCRGKGLTAIPANLPETMTEI----------RLELNGIK--------------------SIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQN-LSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNP-----------IETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTE--DYHLNSECTSDVAC 513
BLAST of slit-2 vs. UniProt/SwissProt
Match: sp|Q8C031|LRC4C_MOUSE (Leucine-rich repeat-containing protein 4C OS=Mus musculus OX=10090 GN=Lrrc4c PE=1 SV=2) HSP 1 Score: 78.5666 bits (192), Expect = 6.024e-14 Identity = 80/310 (25.81%), Postives = 126/310 (40.65%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPD---QNSGVNQASIIVSKKSEFDF----------YSCLIINENGNATV 1194
LK+L + N + SI S AF+ + L+ LDL RL +I F+ LS L L L N + SF+GL+ +Q L M ++++ + + L +NLA N L L +D L+ ++L +NP+NC+C + WL+ + RD +P ++ C P NLKG I L F C P + D+ VT + AE+ C R +L+ + + P+ G + I V +F Y+C++ N GN T
Sbjct: 150 LKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQS-LVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWI------RDMAPSNTACCAR---CNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKC------------RASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTA 437
BLAST of slit-2 vs. TrEMBL
Match: I1ZIL5 (Slit-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 997.653 bits (2578), Expect = 0.000e+0 Identity = 505/506 (99.80%), Postives = 505/506 (99.80%), Query Frame = 1
Query: 97 MYIFRCIYRXXXXXXXXXXXXXVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW 1614
MYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENN FNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW
Sbjct: 1 MYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNLFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW 506
BLAST of slit-2 vs. TrEMBL
Match: A0A5P8I4L0 (PXDN-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 268.855 bits (686), Expect = 2.416e-79 Identity = 168/453 (37.09%), Postives = 243/453 (53.64%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPV-CEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNS--QVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINS---PPNTVNQFNLRNNITKSSVILKEFDKLHV-NYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVP 1536
CP +C++ AC+ +L C GLLQIP + K+I+SNQ F P LTY+N S YG ++K+ + C L SI S FSHL L+ LDLS N L I P+TFK+L L+ L LD N+ +Q + SFRGL V LS+ DC+L L E +IS L L L +N+L + F +LF L +L + NPFNC+C L+WL L +R K + S S R+ N C YP +KG I +L + F C P+L+ ID+ +TS +A+++CIS+ ++S V W + + Y + + +AS+ V +KS D Y C+I N N TV I I WP +N+ PN + + N T LHV + + KQ+T +EM+ + GTF IT++ F+ +Y + K + K YE + S+SQTYD+P
Sbjct: 26 CPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFSSPHLTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCTCNLRWLNSVLVSRKKAINLS---SSKRIPNQAQCNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTCISEPKAHSSPDVIWMTEHKNT-----YVPEIQSIEKASLSVLRKSRIDKYKCVIKNNNDYVTVVISIHWPVKRVNNASQSLNTLGVSPNDMIPYLPNANST-----------LHVRSVFYEKQFTLLEMIGGVVGTFTITMILFLCIYRHLAMTMKRNDKKKWYLSYETAIGSDSQTYDIP 459
BLAST of slit-2 vs. TrEMBL
Match: A0A0R3SAT8 (Ig-like domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS1502 PE=4 SV=1) HSP 1 Score: 196.052 bits (497), Expect = 1.257e-50 Identity = 157/503 (31.21%), Postives = 249/503 (49.50%), Query Frame = 1
Query: 178 RPTKDSECPELCNQGACKLTMLLCETPGLLQ-IPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQI--SGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLL---RL------TNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTS---------EITAE--ISCISDDMSNSQVKW----RYRYNLSPLFYRYPDQNSGVNQASI---IVSKKSEFD------FYSCLIINENGNATVDIKIKWPTLNKEYVESPINSP--PNTVNQFNLRNNITKSSVILK------EFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYH 1554
R + E ++C+ C + C+ G L +P + P GI+KVI+ +Q F L+ N+S Y +++LTI +C L +IES FS L L +LDLS N L I NTF L L L LD N+ L L ++F L V SLSM++C L+ L+ E + + SG LTTL L N L L F+ FR L L+L NPF C C+L WL+ LQ R +R DN ++ RL +P+CE P L+G I +L+ F C P+++ +++ TS TA I C + Q+ W R+ L PL + GV + S+ +++K S D ++C+ I+ GN + D+ +KWPTL P NS P + ++ + + + + L+ + D+L + ++K++T +E++ A+ GTF T++ F++ Y+++ R + K+ K VY +P+ YH
Sbjct: 24 REVRADEVCQICD--GCIYGSISCQEAGRLHMLPNDLPSGIRKVIIVSQRFDSQFLSRPNISSYSLPGSEIQELTIMDCGLRAIESRTFSGLNSLTKLDLSKNSLSRIQGNTFSGLRLDLLRLDDNQGLTLDAEAFENLTVSSLSMQNCGLRSLSFEVFRPLLQSGTLTTLRLTSNSLTTLDARFEPFFRNLSFLSLAKNPFVCDCKLMWLSRILQ-RKRRADNDDAFPMINDDRLLIEPDDDHPICESPGRLRGKQIVSLASSDFYCGPPQMRALEVDFTSLRVGGSEAVNTTAGILIKCAAQGSPEMQLTWFRRDRWGAGLIPL-SGLRQISPGVVEVSVSRSLLAKNSTSDSEDSGELFTCMGIDTYGNTSADLFLKWPTL-------PTNSAVKPQSPDKRSSLESSSSDTFYLEGEQQRFQTDRLD-EFFFMKKFTILELIGAVVGTFTATIMLFLMGYILLYVRHRQQYPKSPSK----TVYPLVSNAGLPKFPDYH 510
BLAST of slit-2 vs. TrEMBL
Match: A0A0R3TNY6 (Ig-like domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9134 PE=4 SV=1) HSP 1 Score: 192.2 bits (487), Expect = 2.918e-49 Identity = 145/479 (30.27%), Postives = 233/479 (48.64%), Query Frame = 1
Query: 178 RPTKDSECPELCNQGACKLTMLLCETPGLLQ-IPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQI--SGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLR---------LTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTS---------EITAE--ISCISDDMSNSQVKW----RYRYNLSPLFYRYPDQNSGVNQASI---IVSKKSE------FDFYSCLIINENGNATVDIKIKWPTLNKEYV---------ESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKN 1479
R K E ++C+ C + C+ G L +P + P GI+KVI+ +Q F L+ N+S Y ++++LTI +C L +IES FS L L +LD+S N L I NTF L L L LD N+ L L ++F L V SLSM++C L+ L+ E + + SG LTTL L N L L F+ FR L L+L NPF C C+L WL+ TLQ R +R DN ++ +P+CE P L+G I L+ F C P+++ +++ +S TA I C + Q+ W R+ L PL + GV + SI +++K S + ++C+ I+ GN + D+ ++WP + SP+ P + + K+ D+L + ++K++T +E++ A+ GTF T++ F++ Y+++ R + K+
Sbjct: 24 REIKADEVCQICD--GCIYGSISCQEAGRLHMLPNDLPPGIRKVIIVSQRFDSQFLSRQNISSYSLPGTVIQELTIMDCGLRAIESRTFSGLNSLTKLDVSKNSLSRIQGNTFSGLRLDLLRLDDNQGLTLDAEAFENLTVSSLSMQNCGLRSLSFEVFRPLLQSGTLTTLRLTSNSLTTLDIRFEPFFRNLSFLSLAKNPFTCDCKLMWLSRTLQ-RKRREDNDDAFPMINDDILLIEPDDDHPICESPSRLRGKQIVTLASTDFYCGPPQMKALEVDFSSFRVGGGETVNTTAGIVIKCAAQGSPEMQLAWFQRDRWGNGLVPL-SGSKHVSPGVVEVSISRSLLAKNSTGGSEELGELFTCMGIDTYGNTSADLSLRWPAFQPTSIVPSQPSDKRNSPV-PPAGDADYLEVDQKSFKT-------DRLD-EFFFMKKFTVLELIGAVVGTFTATIMLFLMGYILLYMRHRQQYPKS 489
BLAST of slit-2 vs. TrEMBL
Match: A0A068YC11 (Variable lymphocyte receptor OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000739800 PE=4 SV=1) HSP 1 Score: 185.652 bits (470), Expect = 5.723e-47 Identity = 161/507 (31.76%), Postives = 241/507 (47.53%), Query Frame = 1
Query: 184 TKDSECPELCNQGACKLTMLLCETPGLLQ-IPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQI--SGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLL---RL------TNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAE-----------ISCISDDMSNSQVKW--RYRYNLSPLFYRYPDQN---SGVNQASIIVS-----KKSEFD----FYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILK---------EFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSES----QTYDVPQMSPYH 1554
T D C +C C + C+ LL +P N P GI+KVI+ +Q F L+ N+S Y + + +LTI +C L +IE+ FS L L +LDLS N L I +TF L L L LD N+ L L ++F L V SLSM++C L+ L++E + + S LTTL L N L L F+ FR L L+L NPF C C+L WL+ TLQ R +R D+ L RL +PVCE P +L+G I +LS F C P+++ +++ + + I C + Q+ W R R P+ R P SGV + SI S KSE + ++CL ++ GN + D+ ++WP L + N RN + SS K + D+L Y ++K++T +E++ A+ GTF T++ F++ Y+++ R + K+ K V S Y V + SP H
Sbjct: 27 TADEVC-RICE--GCTYGSISCQEADLLHMLPNNLPNGIEKVIIVSQRFDSQFLSRQNISSYTLPGVNIHELTIMHCGLRAIEAGTFSGLSSLTKLDLSKNSLSRIQGHTFSGLRLDLLRLDDNQGLTLDSEAFENLTVSSLSMQNCGLRSLSYEVFQPLVQSRSLTTLRLTSNSLTTLDARFEPFFRNLSFLSLARNPFVCDCKLVWLSRTLQ-RKRRADSDDAFRRLNDDRLLIVPDDDHPVCESPNHLRGKHIVSLSTRDFFCGPPQMRALEVDFSDLRVGQSETFNMTGVVLIKCAAQGSPEMQLAWFRRDRRGGEPI--RLPGLRQVASGVVEVSISHSLFAKNSKSETEDAGQLFTCLGVDTYGNTSADLSLRWPALPLLSPLP-------SSPTSNNRNPMEPSSGDSKYLNNDKGYFQSDRLD-EYFFMKKFTILELIGAVVGTFTATILLFLMGYILLYMRHRQQYPKSPSKTVYPLVTSTGLPKFPDYQVLESSPQH 519
BLAST of slit-2 vs. Ensembl Cavefish
Match: lrrc4cb (leucine-rich repeat-containing protein 4C-like [Source:NCBI gene;Acc:103034014]) HSP 1 Score: 81.6481 bits (200), Expect = 8.063e-16 Identity = 90/338 (26.63%), Postives = 143/338 (42.31%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFY-----RYPDQNSG-VNQASIIVSKKSEFDFYSCLIINENGNATVDIKIK-----------WPTLNKEYVESPINSPPNT 1266
LK+L + N + SI S AF+ L L+ LDL RL ++ F+ L L L + N+ + SF+GLV + L M ++I+ S + L LNLA N L ++ +D R L ++L +NP+NC+C + WL+ L R+ P ++ C P +LKG I L FQC P + D+ VT E+ C ++ +++ V W N S L + R QN G +N S+ + + Y+C + N GN + + + + T+ E +ESPI+ T
Sbjct: 151 LKELWLRNNPIESIPSYAFNRLPSLRRLDLGELKRLSYVSDGAFEGLGNLRYLNLGMCNLKEVPNIQPLVRLDELEMSGNQLTVIRPGSFKGLVHLHKLWMMHAQVQIIERNSFDDLQS-LGELNLAHNNLTFVPHDLFTPLRHLQRVHLHHNPWNCNCDILWLSWWL------RETVPTNTSCCAR---CYSPPSLKGRYIGELDQSYFQCYAPVIVESPADLNVTEGTAVELKCRTNSLTS--VSW-LTPNGSVLTHGASKGRVTVQNDGTLNFTSVTM---QDMGTYTCKVSNMLGNVSASVLLNVTSVDNSGFSYFTTVTVETIESPIDGDGRT 472
BLAST of slit-2 vs. Ensembl Cavefish
Match: lrrc4.2 (leucine rich repeat containing 4.2 [Source:ZFIN;Acc:ZDB-GENE-030131-7997]) HSP 1 Score: 75.0998 bits (183), Expect = 8.457e-14 Identity = 74/281 (26.33%), Postives = 116/281 (41.28%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRI--DIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDF----------YSCLIINENGNA 1188
LK L + C+L E S L+ L+EL++S N I P +F+ L SLK L + ++R + +++F + L LNLA N L L +D L L+L +NP+ C C + WLA L R+ P +S C P +L+G + + +FQC P + D+ +++E AE+ C + MS+ V+W L G N I V +F Y+C++ N GN+
Sbjct: 192 LKYLNLGMCNLR--EMPVLSPLVGLEELEMSENYFPEIKPGSFRGLKSLKKLWIMNSRITTMERNAFDDVTA------------------------LVELNLAHNNLSSLPHDLFAPLSYLVELHLHHNPWRCDCDVVWLAWWL------REYIPTNS---TCCGRCHTPAHLRGRYLVEVDQTTFQCSAPFILDAPRDLNISAERVAELKCRTAPMSS--VRW--------LLPNGTVLTHGSNHPRIYVLNDGTLNFSNVLASDTGVYTCMVTNMAGNS 427
BLAST of slit-2 vs. Ensembl Cavefish
Match: lrrc4ca (leucine-rich repeat-containing protein 4C [Source:NCBI gene;Acc:103046976]) HSP 1 Score: 74.7146 bits (182), Expect = 1.189e-13 Identity = 76/303 (25.08%), Postives = 124/303 (40.92%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFD--FYSCLIINENGNATVDIKI 1206
LK+L + N + SI S AF+ + L+ LDL RL +I F+ LS L L + N+ + SF+GLV +Q L M ++ + + + L LNLA N L L +D L+ ++L +NP+NC+C + WL+ L+ + C P + KG I L F C P + D+ VT + AE+ C + +++ V W Y + S +N ++ + + D Y+C++ N GN T +
Sbjct: 151 LKELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLGMCNLKEIPNLIPLVRLDELEMSGNQLSVIRPGSFKGLVHLQKLWMMHAQIQTIERNAFDDLQS-LVELNLAHNNLTLLPHDLFTPLHHLERVHLHHNPWNCNCDILWLSWWLKEMVPANTSCCAR---------CSTPTSHKGRYIGELDQNYFHCYAPVIVEPPADLNVTEGMAAELKCRASSLTS--VSWITPNGSIMTHGAYKVRISVLNDGTLNFTNVTMQDTGTYTCMVSNSAGNTTASATL 441
BLAST of slit-2 vs. Ensembl Cavefish
Match: slit2 (slit homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-3]) HSP 1 Score: 75.0998 bits (183), Expect = 1.321e-13 Identity = 76/255 (29.80%), Postives = 116/255 (45.49%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLS-LKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F L T + + + L+K+ +S+ ++ IE F + EL L+SNRL ++ + K L+ L+TL+L SN+ ++ SF GL L L+L DN + ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I++++ F C+
Sbjct: 487 DLACPEKCR---CEGTTVDCSGQKLTKIPDHIPQYTAELRLNNNEFSV--LEATGIFKKLPQ---LRKINLSSNRISDIEEGTFEGAAGVNELILTSNRLENVHHSMLKGLTGLRTLMLRSNKISCVSNSSFTGLSSVRL------------------------LSLYDNLITSIAPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGEWL--RRKR---------IVTGNPRCQNPYFLKEIPIQDVAAQDFACE 697 HSP 2 Score: 71.2478 bits (173), Expect = 2.088e-12 Identity = 74/273 (27.11%), Postives = 114/273 (41.76%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
+CPE C C ++ C GL +IP N P I ++ L QN S+ I AFS L+ +DLS+N++ + ++F+ L SL +LVL N+ +L K F GL L + + + Q L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ +N + S R C P+ L I + F+C ++ K+ A+++C
Sbjct: 264 QCPEFC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------SIKVIPPGAFSPYKRLRRIDLSNNQISELAADSFQGLRSLNSLVLYGNKITELPKGLFEGLFSLQLLLLNANKLNCLRVDAFQDLQNLNLLSLYDNKLQTIAKGTFSSLRSIQTLHLAQNPFMCDCHLKWLADYLQ------ENPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCS--GVEDYRSKLGGSCFADLAC 490
BLAST of slit-2 vs. Ensembl Cavefish
Match: lrrc4ba (leucine-rich repeat-containing protein 4B-like [Source:NCBI gene;Acc:103034410]) HSP 1 Score: 72.0182 bits (175), Expect = 7.512e-13 Identity = 73/286 (25.52%), Postives = 124/286 (43.36%), Query Frame = 1
Query: 379 IILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKW-----------RYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATV 1194
I L+ L + C L I + + L+ L+EL+LS NRL I P +F+ L SL+ L L ++ + +++F L +S+++ LNL+ N L L +D + L+ ++L +NP+ C+C + WL+ L ++ P ++ C P LKG I L F C P + D+ VT + AE+ C + S + V W YR +S L + +N ++ + + Y+C++ N GN T
Sbjct: 177 INLRYLNLGMCGLKDIPN--LTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFDDL-----------------KSLEE-------LNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCNCDVLWLSWWL------KETVPSNTTCCAR---CHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRT-GTSMTSVNWITPNGTLMTHGSYRVRISVL------HDGTLNFTNVTLRDTGQ---YTCMVTNSAGNTTA 417
BLAST of slit-2 vs. Ensembl Sea Lamprey
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25]) HSP 1 Score: 68.9366 bits (167), Expect = 1.464e-12 Identity = 74/303 (24.42%), Postives = 128/303 (42.24%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIP--KLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFD--FYSCLIINENGNATVDIKI 1206
L+ L + N + I + F+ + LQ LDL +L FI F+ LS L+ L L NR L SF+GL ++ L + ++++ + ++ L LNLA N L L +D + L+ ++L +NP+ C C + WL+ L R+N P ++ C P + K ++ L F C P ++ D+ ++ + AE+ C + S S V W S Y + S ++ ++ + + D Y+CL+ N GN+T +
Sbjct: 105 LRDLWLRNNPIEDISAYTFTRIPSLQRLDLGELTKLQFISNEAFEGLSNLRYLNLGMCNLREVPKLSPLVRLEELELSGNRIEILRPGSFQGLANLRKLWIMHSEVRLVERNAFDELQS-LKELNLAHNSLMSLPHDLFSPLQKLERVHLHHNPWTCDCDILWLSWWL------RENVPNNATCCAR---CALPADRKAINLWELDSSRFTCYPPLIEVPPSDVNISEGMAAELRCRAPS-SASSVTWITPNGTSMTHGSYKIRISVLHDGTLNFTNVTVQDTGIYTCLVANSVGNSTASATL 396
BLAST of slit-2 vs. Ensembl Sea Lamprey
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]) HSP 1 Score: 66.2402 bits (160), Expect = 1.667e-11 Identity = 67/278 (24.10%), Postives = 122/278 (43.88%), Query Frame = 1
Query: 508 TFKSL-SLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKL--QRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIV---SKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILK 1320
F+ L SLK L L N + + +F+GLV ++ L + H+++L + + L L L +NRL ++ L L L++N C C+L WLA L+ S L CE+P+ L+G S+ +++ F C+ P++ + D+ VT T + C ++ + W + N + D+ + Q ++ ++ ++ Y C+ N G ++K P + Y + P +PP V Q + + SV L+
Sbjct: 42 AFEDLESLKYLYLYKNEIQSIDRHAFKGLVSLEQLYIHFNHIEVLEPNTFVDLP-KLERLFLHNNRLSRIATGTFTQLSSLRRLRLDSNRLVCDCELVWLAELLRAFAG--------SGGTLAAATCEHPRRLQGRSVSSITAQEFHCESPRITSEPHDVDVTPGNTVYLRCRAEGNPKPAIIWLHNSNEIAM---AEDERRNLLQDGTLMIRDTRHTDQGTYQCMARNVAG------EVKAPEVVLRYFDVP--APPTFVIQPHDTEVLVGESVTLE 299
BLAST of slit-2 vs. Ensembl Sea Lamprey
Match: islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:ZFIN;Acc:ZDB-GENE-050320-95]) HSP 1 Score: 64.6994 bits (156), Expect = 3.972e-11 Identity = 72/313 (23.00%), Postives = 126/313 (40.26%), Query Frame = 1
Query: 352 NLSRYGSEEI-ILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLL-FIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQ---RIDIKVT---SEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASI----IVSKK----------------SEFDFYSCLIINENGNATVDIKI 1206
+LSR EEI ++ L +S+ L SIE + L+ L+ LDLS+N+L F + + +L+ L L++N ++L +D+F L L +L L N + L +L L NP CSC+ +WL L T + + N C P LKG +++ + V +C P ++ D++ T S+ + C +D + V W+ R + D+ +A + ++ K+ SE Y+C+ N+ G ++ +I
Sbjct: 68 SLSRDAFEEIPLMSSLWLSHNELVSIEKGTLAGLVQLRNLDLSNNQLADFSWEDLRNLTALQVLKLNNNNLVRLPRDAFETLT------------------------DLRSLRLHHNLFATIEEGTFENLHALSHLLLYENPLRCSCKARWLPAWLNTTSI--------DIPSKENIACAEPDELKGQAVQQMPDV--ECVAPTVRLSSSPDVRETRLYSDFAVVLDCQADGLPAPTVSWKLRKEGGEIDLGVFDEEKVPEEAVVETNDVLDKRVMAFRNGTLVIPQLSESEEGAYTCVATNDMGESSASARI 346
BLAST of slit-2 vs. Ensembl Sea Lamprey
Match: LGI1 (leucine rich glioma inactivated 1 [Source:HGNC Symbol;Acc:HGNC:6572]) HSP 1 Score: 63.5438 bits (153), Expect = 5.810e-11 Identity = 55/188 (29.26%), Postives = 83/188 (44.15%), Query Frame = 1
Query: 394 LTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLD---NLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
LT + I + FSHL L L L S+ I + FK L L L +++N ++++++FRGL K LTH L+LA+N+L L D +F+GLD +++L N +C C++KWL L + N+ H + C P G S +LS F C
Sbjct: 56 LTFDDADFNQIANGTFSHLPTLHVLLLGSSSFS-IRDDAFKGLVKLHYLFIENNIIDEISRNAFRGL------------KTLTH------------LSLANNKLRSLPRD---VFKGLDAMTDVDLRGNALHCDCKMKWLVSWLHST-----NASVHDI------TCASPPEFAGRSTRSLSASDFSC 204
BLAST of slit-2 vs. Ensembl Sea Lamprey
Match: flrt3 (fibronectin leucine rich transmembrane 3 [Source:ZFIN;Acc:ZDB-GENE-030131-1988]) HSP 1 Score: 58.151 bits (139), Expect = 2.043e-9 Identity = 65/240 (27.08%), Postives = 103/240 (42.92%), Query Frame = 1
Query: 220 GACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLT--SIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSND-FDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSI 930
GA L +L L +P+ PRG++++ L + ++ L G+ LK+L + L+ SI AF L L EL L+ N + P L+ L L NR +++ + GL +Q L L+L+ N L L FD L + L L++ NNP+ C+C L W LQ KRR S+ + VC+ P+ +G+ +E L++
Sbjct: 152 GAAGLKVLFLSRNLLSAVPIGLPRGLEELRLDDNRVGA--ISEQALGGLGN----LKRLFLEGNQLSEKSIAERAFRDLDSLAELSLARNAFAAV-PANLPGTRLERLYLQDNRISRVSAGALAGL--------------------RQ----LARLDLSGNSLGVLPQGVFDDLSQ-LAQLSVRNNPWRCTCALLW----LQEWMKRRS-----SVTMVRGMVCQAPETARGTPLEGLAL 350
BLAST of slit-2 vs. Ensembl Nematostella
Match: EDO48179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK32]) HSP 1 Score: 56.9954 bits (136), Expect = 1.772e-8 Identity = 58/246 (23.58%), Postives = 113/246 (45.93%), Query Frame = 1
Query: 382 ILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNR---NLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLN---LENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ----IPKL------QRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNL 1065
+L+KL + L+ I+ F HL+ L+ L+L++NR+ I +F L SL+ L L +N ++ FRGL + SL + + + + + + LNL+ N + + + F+G+D L L + C C++KW L++R S +H++ C +P+ L S+ N++ +F C IP++ Q+ + + + + S+ +++WR Y +
Sbjct: 347 VLRKLNLERNRLSHIQDTTFKHLLALKVLNLANNRIYHISQGSFSDLRSLEGLDLSNNDISWTVEEMNGPFRGLTNLASLRLDGNRITAIAATAFLGLEN-IKYLNLSANIITSIQENS---FQGMDKLQKLWLNTSQLMCDCKIKWFGSWLRSRP-----STRHTV----RARCLHPQTLYMKSVFNITPDAFVCDTSNPIPQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEV 579
BLAST of slit-2 vs. Ensembl Nematostella
Match: EDO47109 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNB0]) HSP 1 Score: 53.5286 bits (127), Expect = 1.565e-7 Identity = 46/169 (27.22%), Postives = 75/169 (44.38%), Query Frame = 1
Query: 466 LDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFR--GLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNP---VCEYPKNLKGSSIENLSIVSFQCQIPK 957
LDL N L + F LSL+ L LD N+ L ++F G +Q L M +L +T + + + + L+L +N + + + L ++L NP +C C+L WL L +R + L L++P C P ++KG + L SF C +
Sbjct: 219 LDLGDNLLEVFEVDAFDGLSLRKLRLDGNK-LDEIPEAFAKVGHFLQELDMSGNYLHEITSDQLLDLHA-IERLDLNENNISKIRIGALRGMKKLRQISLSGNPLSCDCRLVWLKHVLDSRQDQ---------LHLSSPQSTTCASPASVKGQTFLGLDARSFLCTCAQ 376
BLAST of slit-2 vs. Ensembl Medaka
Match: lrrc4cb (leucine rich repeat containing 4C [Source:NCBI gene;Acc:101160634]) HSP 1 Score: 78.5666 bits (192), Expect = 6.748e-15 Identity = 77/296 (26.01%), Postives = 124/296 (41.89%), Query Frame = 1
Query: 385 LKKLTISNCSLTSIESEAFSHLIYLQELDLSS-NRLLFIYPNTFKSLS-----------------------LKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQR--IDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFD--FYSCLIINENGN 1185
LK+L + N + SI S AF+ + L+ LDL RL +I FK LS L+ L + N+ + SF GL +Q L M ++ + S + L LNLA N L +L +D L+ ++L +NP+NC+C + WL+ L+ + C P KG I L FQC +P + D+ VT + AE+ C ++ M++ + W Y + S +N ++ + + D Y+C++ N GN
Sbjct: 151 LKELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLSYISELAFKDLSNLRYLNLGMCNLKEIPNIIPLVKLEELEMSGNQLTVIKPSSFTGLANLQKLWMMHSQVQTIERNSFDDLQS-LVELNLAHNNLTFLPHDLFTPLHHLERVHLHHNPWNCNCDILWLSWWLKETVPANTSCCAR---------CHTPSVFKGRYIGELDHSYFQCDVPVIVEPPSDLNVTEGMGAELKCRTNSMTS--ISWLTPNGSMVTHGAYKVRLSVLNDGTLNFTSVTMQDTGTYTCMVSNTAGN 434
BLAST of slit-2 vs. Ensembl Medaka
Match: slit2 (slit guidance ligand 2 [Source:NCBI gene;Acc:101173607]) HSP 1 Score: 78.1814 bits (191), Expect = 1.388e-14 Identity = 79/257 (30.74%), Postives = 115/257 (44.75%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLT--YTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F T + L L+K+ +SN +T IE F + EL L+SN+L I+ + K L L+TL+L SNR ++ SF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 511 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPH-------LRKINLSNNRITDIEEGTFEGASGVNELILTSNKLENIHHSMLKGLGGLRTLMLRSNRISCVSNSSFVGLSSVRL------------------------LSLYDNQVTSMTPGAFDTLHS-LSTLNLLANPFNCNCHLAWLGDWL--RRKR---------IVTGNPRCQNPYFLKEIPIQDVAVQDFACE 721 HSP 2 Score: 73.559 bits (179), Expect = 4.646e-13 Identity = 75/280 (26.79%), Postives = 122/280 (43.57%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
+CPE C C ++ C GL +IP N P I ++ L QN ++ I + AFS L+ +DLS+N++ + + F+ L SL +LVL N+ +++K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C IP + K+ + A+++C
Sbjct: 280 QCPESC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------AIKVIPAGAFSPYKRLRRIDLSNNQISELASDAFQGLRSLNSLVLYGNKITEISKGLFEGLFSLQLLLLNANKIACLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFICDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCSAREQYFIPGTEDYRSKLGGDCFADLAC 514 HSP 3 Score: 56.6102 bits (135), Expect = 6.410e-8 Identity = 64/255 (25.10%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLS--RYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNT--FKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C T + C GL +P N PR +++ L+ N ++T + + R+ L+ L + +T+IE AF L L+ L L+ N L ++P + L L L N+ + + +FRG V +++L + H+ + + + + L L L +N + LS F+ + + L L +N C C + WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 36 CPTQC---SCTGTTVDCHGQGLRSVPRNIPRNTERLDLNANNLT--KITKADFAGLRH------LRVLQLMENKITTIERGAFQDLKELERLRLNRNNLA-VFPELLFLGTTKLHRLDLSENQIQGVPRKAFRGAVEIKNLQLDYNHISCIEDGAFRALRD-LEVLTLNNNNISRLSVASFNHMPK-LRTFRLHSNNLQCDCHVAWLSEWLRQR-------PRLGLYT----QCMSPPHLRGHNVAEVQKKEFVC 265
BLAST of slit-2 vs. Ensembl Medaka
Match: slit2 (slit guidance ligand 2 [Source:NCBI gene;Acc:101173607]) HSP 1 Score: 78.1814 bits (191), Expect = 1.393e-14 Identity = 79/257 (30.74%), Postives = 115/257 (44.75%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLT--YTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F T + L L+K+ +SN +T IE F + EL L+SN+L I+ + K L L+TL+L SNR ++ SF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 455 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPH-------LRKINLSNNRITDIEEGTFEGASGVNELILTSNKLENIHHSMLKGLGGLRTLMLRSNRISCVSNSSFVGLSSVRL------------------------LSLYDNQVTSMTPGAFDTL-HSLSTLNLLANPFNCNCHLAWLGDWL--RRKR---------IVTGNPRCQNPYFLKEIPIQDVAVQDFACE 665 HSP 2 Score: 70.8626 bits (172), Expect = 3.013e-12 Identity = 74/274 (27.01%), Postives = 121/274 (44.16%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISC 1011
+CPE C C ++ C GL +IP N P I ++ L QN ++ I + AFS L+ +DLS+N++ + + F+ L SL +LVL N+ +++K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C + R K+ + A+++C
Sbjct: 232 QCPESC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------AIKVIPAGAFSPYKRLRRIDLSNNQISELASDAFQGLRSLNSLVLYGNKITEISKGLFEGLFSLQLLLLNANKIACLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFICDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCSGTEDYR--SKLGGDCFADLAC 458
BLAST of slit-2 vs. Ensembl Medaka
Match: slit2 (slit guidance ligand 2 [Source:NCBI gene;Acc:101173607]) HSP 1 Score: 78.1814 bits (191), Expect = 1.425e-14 Identity = 79/257 (30.74%), Postives = 115/257 (44.75%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLT--YTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F T + L L+K+ +SN +T IE F + EL L+SN+L I+ + K L L+TL+L SNR ++ SF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 515 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPH-------LRKINLSNNRITDIEEGTFEGASGVNELILTSNKLENIHHSMLKGLGGLRTLMLRSNRISCVSNSSFVGLSSVRL------------------------LSLYDNQVTSMTPGAFDTLHS-LSTLNLLANPFNCNCHLAWLGDWL--RRKR---------IVTGNPRCQNPYFLKEIPIQDVAVQDFACE 725 HSP 2 Score: 73.1738 bits (178), Expect = 4.895e-13 Identity = 75/280 (26.79%), Postives = 122/280 (43.57%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
+CPE C C ++ C GL +IP N P I ++ L QN ++ I + AFS L+ +DLS+N++ + + F+ L SL +LVL N+ +++K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C IP + K+ + A+++C
Sbjct: 284 QCPESC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------AIKVIPAGAFSPYKRLRRIDLSNNQISELASDAFQGLRSLNSLVLYGNKITEISKGLFEGLFSLQLLLLNANKIACLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFICDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCSAREQYFIPGTEDYRSKLGGDCFADLAC 518 HSP 3 Score: 56.6102 bits (135), Expect = 6.750e-8 Identity = 64/255 (25.10%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLS--RYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNT--FKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C T + C GL +P N PR +++ L+ N ++T + + R+ L+ L + +T+IE AF L L+ L L+ N L ++P + L L L N+ + + +FRG V +++L + H+ + + + + L L L +N + LS F+ + + L L +N C C + WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 36 CPTQC---SCTGTTVDCHGQGLRSVPRNIPRNTERLDLNANNLT--KITKADFAGLRH------LRVLQLMENKITTIERGAFQDLKELERLRLNRNNLA-VFPELLFLGTTKLHRLDLSENQIQGVPRKAFRGAVEIKNLQLDYNHISCIEDGAFRALRD-LEVLTLNNNNISRLSVASFNHMPK-LRTFRLHSNNLQCDCHVAWLSEWLRQR-------PRLGLYT----QCMSPPHLRGHNVAEVQKKEFVC 265
BLAST of slit-2 vs. Ensembl Medaka
Match: slit2 (slit guidance ligand 2 [Source:NCBI gene;Acc:101173607]) HSP 1 Score: 78.1814 bits (191), Expect = 1.483e-14 Identity = 79/257 (30.74%), Postives = 115/257 (44.75%), Query Frame = 1
Query: 190 DSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLT--YTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ 948
D CPE C C+ T + C L +IP + P+ ++ L+N F T + L L+K+ +SN +T IE F + EL L+SN+L I+ + K L L+TL+L SNR ++ SF GL L L+L DN++ ++ FD L L LNL NPFNC+C L WL L R KR + NP C+ P LK I+++++ F C+
Sbjct: 515 DLACPEKCR---CEGTTVDCSNQKLTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPH-------LRKINLSNNRITDIEEGTFEGASGVNELILTSNKLENIHHSMLKGLGGLRTLMLRSNRISCVSNSSFVGLSSVRL------------------------LSLYDNQVTSMTPGAFDTLHS-LSTLNLLANPFNCNCHLAWLGDWL--RRKR---------IVTGNPRCQNPYFLKEIPIQDVAVQDFACE 725 HSP 2 Score: 73.1738 bits (178), Expect = 5.005e-13 Identity = 75/280 (26.79%), Postives = 122/280 (43.57%), Query Frame = 1
Query: 196 ECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSL-SLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCH-LKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQ------IPKLQRIDIKVTSEITAEISC 1011
+CPE C C ++ C GL +IP N P I ++ L QN ++ I + AFS L+ +DLS+N++ + + F+ L SL +LVL N+ +++K F GL L + + + + L ++ + + L L+L DN+L+ ++ R + L+L NPF C C LKWLA LQ DN + S R C P+ L I + F+C IP + K+ + A+++C
Sbjct: 284 QCPESC---TCSNNIVDCRGKGLTEIPTNLPETITEIRLE-QN-----------------------------AIKVIPAGAFSPYKRLRRIDLSNNQISELASDAFQGLRSLNSLVLYGNKITEISKGLFEGLFSLQLLLLNANKIACLRVDAFQDLHN-LNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFICDCHLKWLADYLQ------DNPIETSGAR-----CTSPRRLANKRIGQIKSKKFRCSAREQYFIPGTEDYRSKLGGDCFADLAC 518 HSP 3 Score: 56.9954 bits (136), Expect = 6.129e-8 Identity = 64/255 (25.10%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLS--RYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNT--FKSLSLKTLVLDSNRNLQLAKDSFRGLV-VQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLS-NDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQC 945
CP C +C T + C GL +P N PR +++ L+ N ++T + + R+ L+ L + +T+IE AF L L+ L L+ N L ++P + L L L N+ + + +FRG V +++L + H+ + + + + L L L +N + LS F+ + + L L +N C C + WL+ L+ R P+ L C P +L+G ++ + F C
Sbjct: 36 CPTQC---SCTGTTVDCHGQGLRSVPRNIPRNTERLDLNANNLT--KITKADFAGLRH------LRVLQLMENKITTIERGAFQDLKELERLRLNRNNLA-VFPELLFLGTTKLHRLDLSENQIQGVPRKAFRGAVEIKNLQLDYNHISCIEDGAFRALRD-LEVLTLNNNNISRLSVASFNHMPK-LRTFRLHSNNLQCDCHVAWLSEWLRQR-------PRLGLYT----QCMSPPHLRGHNVAEVQKKEFVC 265
BLAST of slit-2 vs. Planmine SMEST
Match: SMESG000033458.1 (SMESG000033458.1) HSP 1 Score: 997.268 bits (2577), Expect = 0.000e+0 Identity = 504/506 (99.60%), Postives = 505/506 (99.80%), Query Frame = 1
Query: 97 MYIFRCIYRXXXXXXXXXXXXXVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW 1614
MYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSG+NQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPI SPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW
Sbjct: 1 MYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGLNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPIKSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW 506
BLAST of slit-2 vs. Planmine SMEST
Match: SMESG000033458.1 (SMESG000033458.1) HSP 1 Score: 942.184 bits (2434), Expect = 0.000e+0 Identity = 481/506 (95.06%), Postives = 483/506 (95.45%), Query Frame = 1
Query: 97 MYIFRCIYRXXXXXXXXXXXXXVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW 1614
MYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLS +SNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSG+NQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPI SPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW
Sbjct: 1 MYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLS----------------------NSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGLNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPIKSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQEIKATW 484
BLAST of slit-2 vs. Planmine SMEST
Match: SMESG000026986.1 (SMESG000026986.1) HSP 1 Score: 329.331 bits (843), Expect = 1.556e-106 Identity = 192/474 (40.51%), Postives = 288/474 (60.76%), Query Frame = 1
Query: 193 SECPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKN--ILKGYEVGVYSESQTYDVPQMSPYHES--NTGRLLDFKTQQEI 1602
+ CP LCNQ +C L C GL IP NPP +VI+ NQ F P L Y NLSRYG+EEI+LK LTI NC LT IESE+FSHL++L E+DLS N+L IYP TFK+L+LK+L L+ NR L+L +SF+GLVV SLS+ +C L L +SIK+I+G+L +L+ N L+ L+ F LLF+ L+ + L N C C++KWL L ++K + + SL++ C P ++G +I L F C P L+ I + +++ +A + C S S++QV W R ++ ++ D ASI V+K S+ D +SC++ NENGN +VD+ IKWP E + + + F+ +N + +S+I + NYL+IKQ+TF+EM+++I TF++T +TF L+Y+ ++ R S K GY+ G+YS++Q YD P+ S +++ + +L+DFKTQ+ I
Sbjct: 19 ANCPVLCNQNSCTYGFLFCVDIGLEMIPENPPPKTTQVIVKNQIFKNPILGYKNLSRYGTEEILLKVLTIQNCGLTEIESESFSHLVHLMEMDLSFNQLQMIYPRTFKALNLKSLKLNGNRLLKLTGNSFQGLVVSSLSLANCGLDSLEFDSIKEIAGHLIRFDLSQNDLKSLNFRFYLLFKRLEEIQLGGNQLKCDCRIKWLNRIL--KSKNQSKASIESLIK-----CSQPYEIRGKAISQLEESQFLCSKPNLKAISVDISTR-SAILYCSSSPNSDTQVSWHLRNAVNYSLHKLEDLIETPFNASIKVNKNSQSDMFSCIVKNENGNVSVDLNIKWP----ENTSETLTDKGHPILLFSTPSNNSSTSIIPQT-----TNYLYIKQFTFLEMIISIGSTFVVTTITFSLIYLCLSRRLNISIGKQSPCKIGYQGGIYSDTQIYDSPRYSTPNKTFQQSAQLIDFKTQRLI 475
BLAST of slit-2 vs. Planmine SMEST
Match: SMESG000026559.1 (SMESG000026559.1) HSP 1 Score: 267.314 bits (682), Expect = 2.367e-82 Identity = 171/453 (37.75%), Postives = 243/453 (53.64%), Query Frame = 1
Query: 199 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPV-CEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNS--QVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINS---PPNTVNQFNLRNNITKSSVILKEFDKLHV-NYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVP 1536
CP +C++ AC+ +L C GLLQIP + K+I+SNQ F P LTY+N S YG ++K+ + C L SI S FSHL L+ LDLS N L I P+TFK+L L+ L LD N+ +Q + SFRGL V LS+ DC+L L E +IS L L L +N+L + F +LF L +L + NPFNC+C L+WL L +R K + S S R+ N C YP +KG I +L + F C P+L+ ID+ +TS +A+++CIS+ ++S V W + + P+ S N AS+ V +KS D Y C+I N N TV I I WP +N+ PN + + N T LHV + + KQ+T +EM+ I GTF IT++ F+ +Y + K + K YE + S+SQTYD+P
Sbjct: 26 CPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFSSPHLTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCTCNLRWLNSVLVSRKKAINLS---SSKRIPNQAQCNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTCISEPKAHSSPDVIWMAEHRNT----YVPEIQSSEN-ASLSVLRKSRIDKYKCVIKNNNDYVTVVISIHWPVKRVNNASQSLNTLGVSPNDMIPYLPNANST-----------LHVRSVFYEKQFTLLEMIGGIVGTFTITMILFLCIYRHLAMTMKRNDKKKWYLSYETAIGSDSQTYDIP 459
BLAST of slit-2 vs. Planmine SMEST
Match: SMESG000002157.1 (SMESG000002157.1) HSP 1 Score: 262.307 bits (669), Expect = 6.535e-80 Identity = 165/471 (35.03%), Postives = 262/471 (55.63%), Query Frame = 1
Query: 193 SECPELCNQGACKLTMLLCETPG-LLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNPFNCSCQLKWLALTLQTRTKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNSQVKWRYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWI-KQYTFIEMVLAICGTFIIT-LVTFILLYVVINYRRKNSRSKNILKGYEVGVYSESQTYDVPQMSPYHESNTGRLLDFKTQQ 1596
+ CP C Q C L+C P L +P+N P+ I + +S QNF+ L+Y LS YG E+I L+ L ++ ++ +IE EAFSHLI L+ LDLS+NRL ++ FK LSL L LD+N NL L + SFRGLVV SLS+K C+LK L++E IK++SG+LT L L+ N+L + F+LLF L+ ++L+ NPF C+CQL+WL +L+ R ++ + S LR TN PK L G ++ +LS + C+ P ++ IDI + + +SC + + + VKWR++ S +YR+ D + + ++ I + ++ D YSC + N G +D+ I WPT N I+S N+ T L + + ++ KQ++ E+++++ T I+T L++ + + +R + + + V SE Q +++ Q E +LLDFKTQQ
Sbjct: 83 AGCPSYCQQQPCLSGKLVCIEPNKLTALPLNIPKIIYHISISGQNFINTTLSYNALSHYGPEQINLRILQLTFTNIENIEPEAFSHLIALKSLDLSNNRLRILHSGIFKGLSLDYLRLDNNENLILLEGSFRGLVVSSLSLKSCYLKNLSYEIIKEVSGHLTKLYLSHNQLSGIDKKFELLFERLELIDLKENPFFCTCQLRWLTKSLKARQHAKEKA-LMSELRCTN-----PKELSGQTLISLSESNLICKPPGVKEIDIFLHGNNSGRLSCEAINALETNVKWRHKLFASENYYRFQDYSPALGRSLISIESRNNVDHYSCYVQNSKGKVNIDVNIMWPTNN-------ISSFIYNSNEVRYIYPETFDDNQLNLNNDNPIEKFFMRKQFSLFELLISMVATLIVTSLLSTLCFCLFFRHRFLPNLFQKSQPMTDSAVTSEVQMHNMSQFPSSQELKANQLLDFKTQQ 540 The following BLAST results are available for this feature:
BLAST of slit-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slit-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slit-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slit-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slit-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slit-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of slit-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slit-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012984 ID=SMED30012984|Name=slit-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1774bpback to top protein sequence of SMED30012984-orf-1 >SMED30012984-orf-1 ID=SMED30012984-orf-1|Name=SMED30012984-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=509bp MKMYIFRCIYRLLLTLIIELLTIEVCLSIRPTKDSECPELCNQGACKLTMback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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