Cyclic nucleotide gated channel 1

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL+K Q
Sbjct:   83 DAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 606          

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKN 1835
            D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ I K 
Sbjct:   83 DAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIAKQ 597          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTF----NIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+++     EIIL P +I  +Y++TWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP+  WV    ++N  W+  Y++ LF A+SHML IGYGR  P S ++ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +IL EL+  LREEI+N+NCR LVA++P+F NAD NF+T +L +LK+EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE+   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL K Q
Sbjct:  164 QRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 675          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++V     EIIL P+RI  +Y+K+WF+ DF+SS+P DYI+L+   +   + +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W  QY++ LF A+SHML IGYGR  P   S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQ+I +YYE+RYQGK+F+E +IL ELSE LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE    L++G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL K Q
Sbjct:  215 QRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNT-EIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLI-VETRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKET--KLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQ 726          

Query:  303 LQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLN-NILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAE 1898
            + K+     +  L + +Q + NK +L++FG+  A++ E+ R ++   WIIHP S FRF W+ +M++ ++ +++ LP+ ++FF E+ +   + F+   D  FLLD+++N RTG++V     EI+L+PR I  RY++TWF+ D +SS+P DYI+L+      L+  +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W  QY+  LF A+SHML IGYG+  P    + WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQ+I  YYE+RYQGK+F+E +IL ELSE LREEIIN+ CR LVA +P+F +AD +F+T VL +L++EV+QPG+L+++EG++G KMYFI  G++ V  +       L++G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE++P MRR  E VA +RL  IGK   +L+++++     S     E
Sbjct:   37 IPKSGPEPKRRHLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGA-EILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGAR-DTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQRKRSEPSPGSSGGIME 571          

Query:  324 KAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPC-----SGFRFCWNSVMVIFLIISVVELPIVLSF-------------FNEDANIGLVFFHCACDILFLLDIIINMRTG-VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMI---LLSHWNACLQFLIPMLQDFPKE-SWVLK-CELLNEKWTN--------------QYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGN-ILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK--SRRMASILARTHCSIYSLDRMSFMRVLEDYP 1775
            +A    R   +L NN  AL +    + +  E   Q T     IH C     S F+  W+ ++++ +I + V  P V +F             F E     L       DI+F++DIIIN RT  V  N    +++  P +I   Y K WFI D V++VPFD + L+S  S+    +            + +L T RLLR+ R+ R +    E         G   ++ LM    L++HW AC+ + I   +   KE +W+ +  + L + +T+              +Y   L+  +S + SIG+G    T+ SE   TII ++ G   YA   G+ +A+I    +    Y+ +  +++E++ + ++P  +RQ++  Y+++ +      + N +L+   +CL+ +I  +  R+L++    F  +    +  + +R +     PG+ ++  G I T +YFI  G V++   +  ++  L     FGE  LL     +   ++ A T+C ++ + R   + VL+ YP
Sbjct:   68 RASHSSRRTSRLHNNVSALGVLSLGADVLPEYKLQPTR----IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEP----LEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLL-LVSTNSDETTTL------------IGLLKTARLLRLVRVARKLDRYSE--------YGAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 563          

Query:  450 IHPC-----SGFRFCWNSVMVIFLIISVVELPIVLSF-------------FNEDANIGLVFFHCACDILFLLDIIINMRTG-VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMI---LLSHWNACLQFLIPMLQDFPKE-SWVLK-CELLNEKWTN--------------QYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGN-ILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK--SRRMASILARTHCSIYSLDRMSFMRVLEDYP 1775
            IH C     S F+  W+ ++++ +I + V  P V +F             F E   I         DI+F++DIIIN RT  V  N    +++  P +I   Y K WFI D V++VPFD + L+S  S+    +            + +L T RLLR+ R+ R +    E         G   ++ LM    L++HW AC+ + I   +   KE +W+ +  + L + +T+              +Y   L+  +S + SIG+G    T+ SE   TII ++ G   YA   G+ +A+I    +    Y+ +  +++E++ + ++P  +RQ++  Y+++ +      + N +L+   +CL+ +I  +  R+L++    F  +    +  + +R +     PG+ ++  G I T +YFI  G V++   +  ++  L     FGE  LL     +   ++ A T+C ++ + R   + VL+ YP
Sbjct:   68 IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEI----VDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLL-LVSTNSDETTTL------------IGLLKTARLLRLVRVARKLDRYSE--------YGAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 525          

Query:  450 IHPC-----SGFRFCWNSVMVIFLIISVVELPIVLSF-------------FNEDANIGLVFFHCACDILFLLDIIINMRTG-VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMI---LLSHWNACLQFLIPMLQDFPKE-SWVLK-CELLNEKWTN--------------QYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGN-ILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK--SRRMASILARTHCSIYSLDRMSFMRVLEDYP 1775
            IH C     S F+  W+ ++++ +I + V  P V +F             F E   I         DI+F++DIIIN RT  V  N    +++  P +I   Y K WFI D V++VPFD + L+S  S+    +            + +L T RLLR+ R+ R +    E         G   ++ LM    L++HW AC+ + I   +   KE +W+ +  + L + +T+              +Y   L+  +S + SIG+G    T+ SE   TII ++ G   YA   G+ +A+I    +    Y+ +  +++E++ + ++P  +RQ++  Y+++ +      + N +L+   +CL+ +I  +  R+L++    F  +    +  + +R +     PG+ ++  G I T +YFI  G V++   +  ++  L     FGE  LL     +   ++ A T+C ++ + R   + VL+ YP
Sbjct:   68 IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEI----VDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLL-LVSTNSDETTTL------------IGLLKTARLLRLVRVARKLDRYSE--------YGAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 525          

Query:  450 IHPC-----SGFRFCWNSVMVIFLIISVVELPIVLSFF----NEDANIG-----LVFFHCACDILFLLDIIINMRTG-VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMI---LLSHWNACLQFLIPMLQDFPKE-SWVLK-CELLNEKWTN--------------QYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGN-ILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK--SRRMASILARTHCSIYSLDRMSFMRVLEDYP 1775
            IH C     S F+  W+ ++++ +I + V  P V +F      + A        L       DI+F++DIIIN RT  V  N    +++  P +I   Y K WFI D V++VPFD + L+S  S+    +            + +L T RLLR+ R+ R +    E         G   ++ LM    L++HW AC+ + I   +   KE +W+ +  + L + +T+              +Y   L+  +S + SIG+G    T+ SE   TII ++ G   YA   G+ +A+I    +    Y+ +  +++E++ + ++P  +RQ++  Y+++ +      + N +L+   +CL+ +I  +  R+L++    F  +    +  + +R +     PG+ ++  G I T +YFI  G V++   +  ++  L     FGE  LL     +   ++ A T+C ++ + R   + VL+ YP
Sbjct:   22 IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLL-LVSTNSDETTTL------------IGLLKTARLLRLVRVARKLDRYSE--------YGAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 479          

Query:  450 IHPC-----SGFRFCWNSVMVIFLIISVVELPIVLSF-------------FNEDANIGLVFFHCACDILFLLDIIINMRTG-VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMI---LLSHWNACLQFLIPMLQDFPKE-SWVLK-CELLNEKWTN--------------QYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGN-ILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK--SRRMASILARTHCSIYSLDRMSFMRVLEDYP 1775
            IH C     S F+  W+ ++++ +I + V  P V +F             F E     L       DI+F++DIIIN RT  V  N    +++  P +I   Y K WFI D V++VPFD + L+S  S+    +            + +L T RLLR+ R+ R +    E         G   ++ LM    L++HW AC+ + I   +   KE +W+ +  + L + +T+              +Y   L+  +S + SIG+G    T+ SE   TII ++ G   YA   G+ +A+I    +    Y+ +  +++E++ + ++P  +RQ++  Y+++ +      + N +L+   +CL+ +I  +  R+L++    F  +    +  + +R +     PG+ ++  G I T +YFI  G V++   +  ++  L     FGE  LL     +   ++ A T+C ++ + R   + VL+ YP
Sbjct:   68 IHHCTIVHYSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEP----LEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFDLL-LVSTNSDETTTL------------IGLLKTARLLRLVRVARKLDRYSE--------YGAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEYTWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGSTPGCLRALSMRFRTTHSPPGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 525          

Query:  306 QKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRS-NGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEI--LNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNP-LLLKKQQTLQDESSEKYCA 1895
            +K + N  K +L+S+ Q ++N+ A+KLFG++ AL KE++RQ+T  +W+IHPCS FRF W+  M++ L+ +++ LP+ +SFFN+D +   + F+C  D +FL+DI++N RTG++     +++IL P+ I   Y++TWF  D +SS+P DYI+L+  +  +    IL AG+AL +LR  K+L  +RLLR+ RLVRY+   +E+  LN+++ F+  FN+I +M+L+ HW+ CLQFL+PMLQ FP  SWV   EL    W  QY+W LF A+SHML IGYGR+PP S ++ WLT++S+++G TCYALF+GHA  LI S D+S+R Y EK KQ++EYMAY KLP++MRQ+I  Y+E+RYQGK F+E  IL ELSE LRE++INYNCR LVA+VP F NAD NF++DV+ +LKYEV+QPG++IIKEGTIGTKMYFI +GVVD+     E+  SLS+G +FGEICLLT +RR+AS+ A T+C+++SL    F  VL+ YP MR+ +E VAAERL  IGKNP ++ +K + L +  S    A
Sbjct:  698 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPESNTITA 1231          

Query:  306 QKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN------ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEI--LNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNP-LLLKKQQTLQDESSEKYCA 1895
            +K + N  K +L+S+ Q ++N+ A+KLFG++ AL KE++RQ+T  +W+IHPCS FRF W+  M++ L+ +++ LP+ +SFFN+D +   + F+C  D +FL+DI++N RTG++     +++IL P+ I   Y++TWF  D +SS+P DYI+L+  +   L +      IL AG+AL +LR  K+L  +RLLR+ RLVRY+   +E+  LN+++ F+  FN+I +M+L+ HW+ CLQFL+PMLQ FP  SWV   EL    W  QY+W LF A+SHML IGYGR+PP S ++ WLT++S+++G TCYALF+GHA  LI S D+S+R Y EK KQ++EYMAY KLP++MRQ+I  Y+E+RYQGK F+E  IL ELSE LRE++INYNCR LVA+VP F NAD NF++DV+ +LKYEV+QPG++IIKEGTIGTKMYFI +GVVD+     E+  SLS+G +FGEICLLT +RR+AS+ A T+C+++SL    F  VL+ YP MR+ +E VAAERL  IGKNP ++ +K + L +  S    A
Sbjct:  698 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPESNTITA 1236          

Query:  306 QKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRS-NGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEI--LNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNP-LLLKKQQTLQDESSEKYCA 1895
            +K + N  K +L+S+ Q ++N+ A+KLFG++ AL KE++RQ+T  +W+IHPCS FRF W+  M++ L+ +++ LP+ +SFFN+D +   + F+C  D +FL+DI++N RTG++     +++IL P+ I   Y++TWF  D +SS+P DYI+L+  +  +    IL AG+AL +LR  K+L  +RLLR+ RLVRY+   +E+  LN+++ F+  FN+I +M+L+ HW+ CLQFL+PMLQ FP  SWV   EL    W  QY+W LF A+SHML IGYGR+PP S ++ WLT++S+++G TCYALF+GHA  LI S D+S+R Y EK KQ++EYMAY KLP++MRQ+I  Y+E+RYQGK F+E  IL ELSE LRE++INYNCR LVA+VP F NAD NF++DV+ +LKYEV+QPG++IIKEGTIGTKMYFI +GVVD+     E+  SLS+G +FGEICLLT +RR+AS+ A T+C+++SL    F  VL+ YP MR+ +E VAAERL  IGKNP ++ +K + L +  S    A
Sbjct:   26 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPESNTITA 559          

Query:  306 QKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRS-NGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEI--LNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNP-LLLKKQQTLQDESSEKYCA 1895
            +K + N  K +L+S+ Q ++N+ A+KLFG++ AL KE++RQ+T  +W+IHPCS FRF W+  M++ L+ +++ LP+ +SFFN+D +   + F+C  D +FL+DI++N RTG++     +++IL P+ I   Y++TWF  D +SS+P DYI+L+  +  +    IL AG+AL +LR  K+L  +RLLR+ RLVRY+   +E+  LN+++ F+  FN+I +M+L+ HW+ CLQFL+PMLQ FP  SWV   EL    W  QY+W LF A+SHML IGYGR+PP S ++ WLT++S+++G TCYALF+GHA  LI S D+S+R Y EK KQ++EYMAY KLP++MRQ+I  Y+E+RYQGK F+E  IL ELSE LRE++INYNCR LVA+VP F NAD NF++DV+ +LKYEV+QPG++IIKEGTIGTKMYFI +GVVD+     E+  SLS+G +FGEICLLT +RR+AS+ A T+C+++SL    F  VL+ YP MR+ +E VAAERL  IGKNP ++ +K + L +  S    A
Sbjct:   26 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPESNTITA 559          

Query:  306 QKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRS-NGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEI--LNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNP-LLLKKQQTLQDESSEKYCA 1895
            +K + N  K +L+S+ Q ++N+ A+KLFG++ AL KE++RQ+T  +W+IHPCS FRF W+  M++ L+ +++ LP+ +SFFN+D +   + F+C  D +FL+DI++N RTG++     +++IL P+ I   Y++TWF  D +SS+P DYI+L+  +  +    IL AG+AL +LR  K+L  +RLLR+ RLVRY+   +E+  LN+++ F+  FN+I +M+L+ HW+ CLQFL+PMLQ FP  SWV   EL    W  QY+W LF A+SHML IGYGR+PP S ++ WLT++S+++G TCYALF+GHA  LI S D+S+R Y EK KQ++EYMAY KLP++MRQ+I  Y+E+RYQGK F+E  IL ELSE LRE++INYNCR LVA+VP F NAD NF++DV+ +LKYEV+QPG++IIKEGTIGTKMYFI +GVVD+     E+  SLS+G +FGEICLLT +RR+AS+ A T+C+++SL    F  VL+ YP MR+ +E VAAERL  IGKNP ++ +K + L +  S    A
Sbjct:   26 EKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPESNTITA 559          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGT----FNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKN 1835
            + +  + +Q   NK +L++FG++ A++KE+ R ++  NWIIHP S FRF W+  M++F++ +++ +P+ ++FF E+     + F+   D  FL+D+++N RTG++      EIIL P +I  +Y+KTWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP + WV   +++N+ W+  Y++ LF A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +ILEEL+E LREEI+N+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV V TK   I   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IGK+
Sbjct:  138 QRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKS 640          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVD--EIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A++KE+ R ++  NWIIHP S FRF W+  M++F++ +++ +P+ ++FF E+     + F+   D  FL+D+++N RTG++   Y D  EIIL P +I  +Y+KTWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  +   N+I +M+LL HW+ CLQFL+PMLQDFP + WV   +++N+ W+  Y++ LF A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +ILEEL+E LREEI+N+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV V TK   I   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +L+ K Q
Sbjct:   83 QRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIV---YEDNTEIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQ 594          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ +++ +P+ ++FF+E      + F+ A D +FL+D+++N RTG+ VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G ++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV    ++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E +IL EL++ L+EEI+N+NCR LVA +P+F NAD NF+T +L +LK+EV+QP + II+EGT+G KMYFI  GV  V TK  KE+   L++G +FGEICLLTK RR AS+ A T+C ++SL    F  VLE+YP MRR  E VA +RL+ IG KN LLL+K Q
Sbjct:   72 QRQFGAMMQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTSWLVFNVASDTIFLVDLVMNFRTGI-VNEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEK--GFDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEDSILNELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPNDYIIREGTVGKKMYFIQHGVASVITKFNKEL--KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQKFQ 583          

Query:  345 SFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++      EIIL P++I  +Y+++WF+ DF+SS+P DYI+L+   +   ++     +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV K +++N+ W  QY++ LF A+SHML IGYG YPP   ++ WLTI+S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQ+I +YYE+RYQGK+F+E +IL EL+E LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +L  K Q
Sbjct:  181 AMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNA-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLI-VETRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE--TKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHKVQ 687          

Query:  345 SFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL---------NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++      EIIL P++I  +Y+++WF+ DF+SS+P DYI+L+   +   ++     +AL ++R  KIL  LRLLR+ RL+RYI H    +         ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV K +++N+ W  QY++ LF A+SHML IGYG YPP   ++ WLTI+S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQ+I +YYE+RYQGK+F+E +IL EL+E LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +L  K Q
Sbjct:  161 AMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNA-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLI-VETRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHHTHTTILHLIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKE--TKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHKVQ 672          

Query:  258 SYNCANF-SLEINDESLQKNTFNKAKEKLRSF--------IQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            S +C +   LE    ++++ T +  +++  SF        +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF E+     + F+   D  FL+D+++N RTG+++     EIIL P+RI  RY+K+WF+ DFVSS+P DYI+L+   +   + +    +AL ++R  K+L  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP++ WV    + N  W  QY++ LF A+SHML IGYG+  P    + WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP ++RQ+I +YYE+RYQGK+F+E +IL ELSE LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ +I+EGT+G KM+FI  GVV + +K  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IG KN LLL K Q
Sbjct:   17 SSHCPHLLPLESLTPAMEEQTLSGGEDEQGSFMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLEDNT-EIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLI-VETRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSKGSKE--TKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESVALDRLDRIGKKNSLLLHKVQ 561          

Query:  189 DGPID--ESLSTDTDTRISDSKPDLSYNCANFSLEINDESL--------QKNTFNKAKEKLRSF--------IQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            DG I   E  S   D  + +S   LS N    S     E L        ++ T +  +++  SF        +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF E+     + F+   D  FL+D+++N RTG+++     EIIL P+RI  RY+K+WF+ DFVSS+P DYI+L+   +   + +    +AL ++R  K+L  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP++ WV    + N  W  QY++ LF A+SHML IGYG+  P    + WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP ++RQ+I +YYE+RYQGK+F+E +IL ELSE LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ +I+EGT+G KM+FI  GVV + +K  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IG KN LLL K Q
Sbjct:   10 DGDISPTEECSPTLDPAVGESNIHLSQNTQTSSQCQGAEQLSSPGKLDGREQTLSGGEDEQGSFMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLEDNT-EIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLI-VETRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSKGSKE--TKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESVALDRLDRIGKKNSLLLHKVQ 586          

Query:  345 SFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF E+     + F+   D  FL+D+++N RTG+++     EIIL P+RI  RY+K+WF+ DFVSS+P DYI+L+   +   + +    +AL ++R  K+L  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP++ WV    + N  W  QY++ LF A+SHML IGYG+  P    + WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP ++RQ+I +YYE+RYQGK+F+E +IL ELSE LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ +I+EGT+G KM+FI  GVV + +K  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IG KN LLL K Q
Sbjct:   33 ALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLEDNT-EIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLI-VETRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSKGSKE--TKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESVALDRLDRIGKKNSLLLHKVQ 539          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGT----FNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +L + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+++     EIIL P++I  +Y++TWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++          FN+I +M+LL HW+ CLQFL+PMLQDFP   WV   +++N+ W+  Y++ LF A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQ++ +YYE+RYQGK+F+E +IL EL+E LREEI+N+NCR LVA++P+F NAD +F+T +L +LK+EV+QP + II+EGTIG KMYFI  GVV V TK  KE+   LS+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IG KN +L+ K Q
Sbjct:   42 QRQLSAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPQKIKRKYLRTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIAMMLLLCHWDGCLQFLVPMLQDFPTNCWVSINKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQRLHDYYEHRYQGKMFDEDSILGELNEPLREEIVNFNCRKLVASMPLFANADPSFVTAMLTKLKFEVFQPTDYIIREGTIGKKMYFIQHGVVSVLTKGNKEV--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQ 553          

Query:  306 QKNTFNKAKEKLRSF--------IQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            Q+ T +  +++  SF        +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF E+     + F+   D  FL+D+++N RTG+++     EIIL P+RI  RY+K+WF+ DFVSS+P DYI+L+   +   + +    +AL ++R  K+L  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP++ WV    + N  W  QY++ LF A+SHML IGYG+  P    + WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP ++RQ+I +YYE+RYQGK+F+E +IL ELSE LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ +I+EGT+G KM+FI  GVV + +K  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IG KN LLL K Q
Sbjct:   26 QEQTLSGGEDEQGSFMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLEDNT-EIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLI-VETRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSKGSKE--TKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESVALDRLDRIGKKNSLLLHKVQ 553          

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL+K Q
Sbjct:   72 DAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 595          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTF----NIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+++     EIIL P +I  +Y++TWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W+  Y++ LF A+SHML IGYGR  P S ++ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +IL EL+  LREEI+N+NCR LVA++P+F NAD NF+T +L +LK+EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE+   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL K Q
Sbjct:  137 QRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 648          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTF----NIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+++     EIIL P +I  +Y++TWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W+  Y++ LF A+SHML IGYGR  P S ++ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +IL EL+  LREEI+N+NCR LVA++P+F NAD NF+T +L +LK+EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE+   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL K Q
Sbjct:  137 QRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 648          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++V     EIIL P+RI  +Y+K+WF+ DF+SS+P DYI+L+   +   + +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W  QY++ LF A+SHML IGYGR  P   S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQ+I +YYE+RYQGK+F+E +IL ELSE LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE    L++G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL K Q
Sbjct:  215 QRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNT-EIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLI-VETRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKET--KLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQ 726          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLN-NILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAE 1898
            + +L + +Q + NK +L++FG+  A++ E+ R ++   WIIHP S FRF W+ +M++ ++ +++ LP+ ++FF E+ +   + F+   D  FLLD+++N RTG++V     EI+L+PR I  RY++TWF+ D +SS+P DYI+L+      L+  +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W  QY+  LF A+SHML IGYG+  P    + WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQ+I  YYE+RYQGK+F+E +IL ELSE LREEIIN+ CR LVA +P+F +AD +F+T VL +L++EV+QPG+L+++EG++G KMYFI  G++ V  +       L++G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE++P MRR  E VA +RL  IGK   +L+++++     S     E
Sbjct:   45 RRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGA-EILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGARDT-RLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSSGGVME 570          

Query:  288 INDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL+K Q
Sbjct:   17 LEDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 542          

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL+K Q
Sbjct:   83 DAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 606          

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL+K Q
Sbjct:   72 DAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 595          

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            D    +  +   + +  S +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ ++V +P+ ++FF E      + F+ A D +FLLD+I+N RTG  VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV   E++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ LREEI+N+NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EG +G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL+K Q
Sbjct:   72 DAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGT-VNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEK--GMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 595          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTF----NIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+++     EIIL P +I  +Y++TWF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N  W+  Y++ LF A+SHML IGYGR  P S ++ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +IL EL+  LREEI+N+NCR LVA++P+F NAD NF+T +L +LK+EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE+   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +LL K Q
Sbjct:  137 QRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNT-EIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 648          

Query:  285 EINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDE 1874
            E N + L+++T +  KE+ ++F Q S+NK A+KLFG+K+AL KEK RQ  +  W+IHPCS FRF W+ +M++ LI +++ LP+ +SFFN+D +I  + F+   D++F+ DI +  RTGV+ N Y DEIIL+P+ I   Y+K+WF+ DF+SS+P DY+YL+  + +  N   SAG+ L +LR  K+L  LRLLR+ RLVRY+   +E LNI+++F+G FN++ LM+LL HWNACLQ+LIPML +FP +SWV +C+L N  W  QYTW LF A+SHMLSIGYGR+PPTS  EAW+TI+S+++G TCYALFVGHAAALI SFDTSKRLY EKFKQ++EYMAY KLP+ +RQ+I NYYE+RYQGK+F+E  IL E SECLRE++INYNCR LVAAVP F  ADQ+F+++V+ +LK+EV+QPG+LIIKEGTIG KMYFI +G+VD+ TK+ E+  SLS+G +FGEI LLT +RR+AS+ A  + ++YSLDR SF+ VLE+YP MRR +E VAAERL  IG+NP ++  ++ L+++
Sbjct:  585 EPNVDPLKQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSNFRFYWDLLMLMLLIANLIILPVAISFFNDDLSIHWIIFNSISDVVFIADIAVKFRTGVVANDYADEIILNPKEIARHYLKSWFVLDFISSIPMDYLYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMEFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPTSIGEAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQVINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEITLLTNARRVASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESVAAERLNKIGQNPSIVSNREDLKED 1114          

Query:  174 SFPYLDG---PIDESLSTDTDTRISDSKPDLSYNCANFS----LEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDE 1874
            S PY  G   P   + S+   +  +   P  S++ A  +    +E  +ES +++T +  KE+ ++F Q S+NK A+KLFG+K+AL KEK RQ  +  W+IHPCS FRF W+ +M++ LI +++ LP+ +SFFN+D +I  + F+   D++F+ DI +  RTGV+ N + DEIIL+P+ I   Y+K+WF+ DF+SS+P DYIYL+    +  N  LSAG+ L +LR  K+L  LRLLR+ RLVRY+   +E LNI+++F+G FN++ LM+LL HWNACLQ+LIPML +FP +SWV +C++ +  W  QYTW LF A+SHMLSIGYGR+PP S  +AW+TI+S+++G TCYALFVGHAAALI SFDTSKRLY EKFKQ++EYMAY KLP+ +RQ+I NYYE+RYQGK+F+E  IL E SECLRE+IINYNCR LVAAVP F  ADQ+F+++V+ +LK+EV+QPG+LIIKEGTIG KMYFI +G+VD+ TK+ E+  SLS+G +FGEICLLT +RR+AS+ A  + ++YSLDR SF+ VLE+YP MRR +E VAAERL  IG+NP ++  ++ L+++
Sbjct:  152 SVPYSSGTSRPFQNTESSREKSTTTGGFPLPSHSAAALADGNFIEQGNESTKQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVEQGKWVIHPCSSFRFYWDLLMLVLLIANLIILPVAISFFNDDLSIHWIIFNTISDVIFIADIAVKFRTGVVTNDFADEIILNPKEIARHYLKSWFMLDFISSIPMDYIYLIFNNKDHYNQFLSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMEFPPDSWVKRCKIEDADWFQQYTWALFKAMSHMLSIGYGRFPPISIGDAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNARRVASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESVAAERLSKIGQNPAIVSNREDLKED 725          

Query:  297 ESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDE 1874
            + L+++T +  KE+ ++F Q S+NK A+KLFG+K+AL KEK RQ  +  W+IHPCS FRF W+ +M++ LI +++ LP+ +SFFN+D +I  + F+   D++F+ DI +  RTG++ N Y DEIIL+P+ I   Y+K+WFI DF+SS+P DY+YL+  + +  N   SAG+ L +LR  K+L  LRLLR+ RLVRY+   +E LNI+++F+G FN++ LM+LL HWNACLQ+LIPML DFP +SWV +C+L N  W  QYTW LF A+SHMLSIGYGR+PPTS  EAW+TI+S+++G TCYALFVGHAAALI SFDTSKRLY EKFKQ++EYMAY KLP+ +RQ+I NYYE+RYQGK+F+E  IL E SECLRE++INYNCR LVAAVP F  ADQ+F+++V+ +LK+EV+QPG+LIIKEGTIG KMYFI +G+VD+ TK+ E+  SLS+G +FGEI LLT +RR AS+ A  + ++YSLDR SF+ VLE+YP MRR +E VAAERL  IG+NP ++  ++ L+++
Sbjct:  593 DPLKQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSNFRFYWDLLMLMLLIANLIILPVAISFFNDDLSIHWIIFNSISDVVFIADIAVKFRTGIVTNDYADEIILNPKEIARHYLKSWFILDFISSIPMDYLYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMDFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPTSIGEAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQVINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEITLLTNTRRTASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESVAAERLNKIGQNPSIVSNREDLKED 1118          

Query:  297 ESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDE 1874
            + L+++T +  KE+ ++F Q S+NK A+KLFG+K+AL KEK RQ  +  W+IHPCS FRF W+ +M++ LI +++ LP+ +SFFN+D +I  + F+   D++F+ DI +  RTG++ N Y DEIIL+P+ I   Y+K+WFI DF+SS+P DY+YL+  + +  N   SAG+ L +LR  K+L  LRLLR+ RLVRY+   +E LNI+++F+G FN++ LM+LL HWNACLQ+LIPML DFP +SWV +C+L N  W  QYTW LF A+SHMLSIGYGR+PPTS  EAW+TI+S+++G TCYALFVGHAAALI SFDTSKRLY EKFKQ++EYMAY KLP+ +RQ+I NYYE+RYQGK+F+E  IL E SECLRE++INYNCR LVAAVP F  ADQ+F+++V+ +LK+EV+QPG+LIIKEGTIG KMYFI +G+VD+ TK+ E+  SLS+G +FGEI LLT +RR AS+ A  + ++YSLDR SF+ VLE+YP MRR +E VAAERL  IG+NP ++  ++ L+++
Sbjct:  593 DPLKQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSNFRFYWDLLMLMLLIANLIILPVAISFFNDDLSIHWIIFNSISDVVFIADIAVKFRTGIVTNDYADEIILNPKEIARHYLKSWFILDFISSIPMDYLYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMDFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPTSIGEAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQVINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEITLLTNTRRTASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESVAAERLNKIGQNPSIVSNREDLKED 1118          

Query:  270 ANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDE 1874
             NF +E  +ES +++T +  KE+ ++F Q S+NK A+KLFG+K+AL KEK RQ  +  W+IHPCS FRF W+ +M++ LI +++ LP+ +SFFN+D +I  + F+   D++F+ DI +  RTGV+ N + DEIIL+P+ I   Y+K+WF+ DF+SS+P DYIYL+    +  N  LSAG+ L +LR  K+L  LRLLR+ RLVRY+   +E LNI+++F+G FN++ LM+LL HWNACLQ+LIPML +FP +SWV +C++ +  W  QYTW LF A+SHMLSIGYGR+PP S  +AW+TI+S+++G TCYALFVGHAAALI SFDTSKRLY EKFKQ++EYMAY KLP+ +RQ+I NYYE+RYQGK+F+E  IL E SECLRE+IINYNCR LVAAVP F  ADQ+F+++V+ +LK+EV+QPG+LIIKEGTIG KMYFI +G+VD+ TK+ E+  SLS+G +FGEICLLT +RR+AS+ A  + ++YSLDR SF+ VLE+YP MRR +E VAAERL  IG+NP ++  ++ L+++
Sbjct:  192 GNF-IEQGNESTKQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSSFRFYWDLLMLVLLIANLIILPVAISFFNDDLSIHWIIFNTISDVIFIADIAVKFRTGVVTNDFADEIILNPKEIARHYLKSWFMLDFISSIPMDYIYLIFDNKDHYNQFLSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMEFPPDSWVKRCKIEDADWFQQYTWALFKAMSHMLSIGYGRFPPISIGDAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQIINYNCRALVAAVPFFTYADQDFVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNARRVASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESVAAERLSKIGQNPSIVSNREDLKED 725          

Query:  150 GSSQKLPTSFPYLDGPIDESLSTDTDTRIS-DSKPDLSYNCANFSLEIND-ESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGT----FNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            G+S+  P + P        S     D R+S  + P  +    +  L  +D E+    TF   + +  S +Q   NK +L++FG++ A++KE+ R ++  NWIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++      EIIL P++I  +Y++TWF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP + WV   +++N+ W+  Y++ LF A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +ILEEL+E LREEI+N+NCR LVA++P+F NAD NF+T +L +L++EV+QP + II+EGTIG KMYFI  GVV V TK   I   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ +G KN +L+ K Q
Sbjct:   63 GASELAPNTTPSTPA----SAPDRRDPRVSFSTAPGPTKTPEDAQLAGDDGEARDAQTF--MQRQFSSMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPKQIKKKYLRTWFVVDFISSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPLDYIIREGTIGKKMYFIQHGVVSVLTK-GSIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRLGKKNSILMHKVQ 630          

Query:  276 FSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
              LE  D + + + F   + ++ + +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ +++ +P+ ++FF+E      + F+ A D +FL+D+++N RTG+ VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G ++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV    ++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ L+EEI+N+NCR LVA +P+F NAD NF+T +L +LK+EV+QP + II+EGT+G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C ++SL    F  VLE+YP MRR  E VA +RL+ IG KN LLL+K Q
Sbjct:   81 LGLEDADPAGRSHGF--MQRQIGAMLQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTTWLVFNVASDTIFLVDLVMNFRTGI-VNEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEK--GFDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEDNILNELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPNDYIIREGTVGKKMYFIQHGVASVITKHNKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQKFQ 608          

Query:  150 GSSQKLPTSFPYLDGPIDESLSTDTDTRIS-DSKPDLSYNCANFSLEIND-ESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGT----FNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            G+S+  P + P        S     D R+S  + P  +    +  L  +D E+    TF   + +  S +Q   NK +L++FG++ A++KE+ R ++  NWIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++      EIIL P++I  +Y++TWF+ DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++           N+I +M+LL HW+ CLQFL+PMLQDFP + WV   +++N+ W+  Y++ LF A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +ILEEL+E LREEI+N+NCR LVA++P+F NAD NF+T +L +L++EV+QP + II+EGTIG KMYFI  GVV V TK   I   LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ +G KN +L+ K Q
Sbjct:  111 GASELAPNTTPSTPA----SAPDRRDPRVSFSTAPGPTKTPEDAQLAGDDGEARDAQTF--MQRQFSSMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPKQIKKKYLRTWFVVDFISSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPLDYIIREGTIGKKMYFIQHGVVSVLTK-GSIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRLGKKNSILMHKVQ 678          

Query:  276 FSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
              LE  D + + + F   + ++ + +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ +++ +P+ ++FF+E      + F+ A D +FL+D+++N RTG+ VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G ++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+P+LQDFP + WV    ++N+ W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI +YYE+RYQGKIF+E NIL EL++ L+EEI+N+NCR LVA +P+F NAD NF+T +L +LK+EV+QP + II+EGT+G KMYFI  GV  V TK  + +  L++G +FGEICLLTK RR AS+ A T+C ++SL    F  VLE+YP MRR  E VA +RL+ IG KN LLL+K Q
Sbjct:   86 LGLEDADPAGRSHGF--MQRQIGAMLQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTTWLVFNVASDTIFLVDLVMNFRTGI-VNEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEK--GFDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEDNILNELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPNDYIIREGTVGKKMYFIQHGVASVITKHNKEM-KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQKFQ 613          

Query:  285 EINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGK-NPLLLKK------------------QQTLQDESSEKYCAESKFSAPP 1919
            ++++E L +  F     +L + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+ +M++ ++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+ V     EIIL P+ I  RY+++WF  DF+SS+P DYI+L+   +   ++     +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV K +++N+ W  QY++ LF A+SHML IGYG YPP   ++ WLTI+S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQ+I +YYE+RYQGK+F+E +IL EL+E LREEII++NCR LVA +P+F NAD NF+T +L +L++EV+QPG+ II+EGT+G KMYFI  GV+ V TK  KE    +S+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IGK N +L  K                  QQ +Q +    +CA    + PP
Sbjct:  171 QMDEERLYQAGF--MHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGI-VKEDSTEIILDPQLIKVRYLRSWFAVDFISSIPVDYIFLI-VETRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTKGSKE--TKISDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETVALDRLDRIGKRNSVLQHKVQRDLNSGVLNYQENEIIQQIVQHDRDMAHCAHLLQTPPP 733          

Query:  480 WNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL-NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELL--------------------NEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFK 1277
            W+ +M++ ++ +++ +P+ ++FF+E+     + F+   D  FL+D+++N RTG++V    D IIL P+ I  RY+K+WF+ DFVSS+P DYI+L+   +   + +    +AL ++R  KIL  LRLLR+ RL+RYI   +E+  ++++  V   N+I +M+LL HW+ CLQFL+PMLQ+FP + W+    ++                    N+ W  QY++ LF A+SHML IGYG+  P S ++ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK +
Sbjct:    1 WDIIMLLLMVGNLIVIPVGITFFHEEDTTAWIVFNVLSDTCFLVDLVLNFRTGIVVEDNTD-IILDPQVIKMRYLKSWFLVDFVSSIPVDYIFLI-VETRIDSEMYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEMTYDLASAVVRIVNLIAMMLLLCHWDGCLQFLVPMLQEFPHDCWISLNGMVVGLAASRTHLRFFAITPVCQNDSWGKQYSYALFKAMSHMLCIGYGQRAPVSMADLWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKMQ 285          

Query:  249 PDLSYNCANFSLE---INDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCA------------CDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLM---ILLSHWNACLQFLIPMLQDFPKES-------WVLKC-----ELLNEKWT-------NQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQ-GKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEIC--LLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYL 1793
            P L++N ++F  +   +   S +KN F   K K ++        Q L L  +   L + KL+      W I   S F+  W+ ++++ +I + +  P   +F   D  +      C              DI+F++DI IN RT  +  +  +E++  P +I   Y K WF+ D V+++PFD +   S   +G    L           + +L T RLLR+ R+ R +    E         G   ++ LM    L++HW AC+ + I  ++  P +S       W+ +      +  N+  T       ++Y   L+   S + S+G+G   P +  E   +I  +L G   YA   G+ +A+I    +    Y+ +  ++KE++ + ++P  +RQ++  Y+++ +      +   +L+   ECL+ +I  +  R L+ +   F  A +  +  + ++ K     PG+ ++  G + T MYF+  G +++  +E  ++A L     FGE         +  A + A T+C ++ + R   + VL+ YP    + 
Sbjct:   24 PQLTFNFSDFRSDKTVVTPPSSEKN-FIPPKVKEKTHHVTEKVTQVLSLGAD--VLPEYKLQAPRIHKWTILHYSPFKAVWDWLILLLVIYTAIFTPYTAAFLLSDQQVENERQKCGYSCNPLNIVDLMVDIMFMVDIFINFRTTYINKN--EEVVSHPGKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSGSGETTTL-----------IGLLKTARLLRLVRVARKLDRYSE--------YGAAVLVLLMCTFALIAHWLACIWYAIGNMER-PVDSLAKDRIGWLDQLGGQIGKPYNDTDTSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNYEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNMVLKGFPECLQADICLHLNRTLLESCKAFNGASKGCLRALAMKFKTTHAPPGDTLVHSGDVITAMYFLSRGSIEI-LREDIVVAILGKNDIFGEPVNQYSRPGKSSADVRALTYCDLHKIVREDMLEVLDMYPEFSEHF 552          

Query:  429 RTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYI--------YLLSYRSNGLNNILSAGKALLMLRRVKILG---------TLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMI---LLSHWNACLQFLIPMLQDFP-------KESWVLKC--------ELLNEKWTNQ------YTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQ-GKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK--SRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSE--KYCAESKFSAPPEYVLGGYYKR 1949
            +T  + I+H C+ F+  W+ +++I    + + +P  +SF  +  N+  +      D++FL+DI++N  T  +      E+I  P+ I   Y+KTWF+ D +S +P+D I         + + +  G     S  + L    RV   G          +RLLR+ R+ R + H  E         G   ++ L+    L +HW AC+ + I   +          K SW+ +              +W         Y   L+  ++ + SIG+G   PT+  E    +  ++ G   YA   G+   +      +   Y+E    +++++   ++PK + +++++Y    +   K  +   +L    + +R +I  +  R +    P FR A    +  + V  +     PG+LI   G     + F++ G ++V  ++ E++A L  G  FG++    +  +   A++ A T+C ++ + R + ++VL+ Y A      +         G   L+ +K   ++ E  E  K   E+    PP++ +   ++R
Sbjct:  184 KTPPHIILHYCA-FKTTWDWIILILTFYTAIMVPYNVSFKTKQNNVAWLVVDSVVDVIFLVDIVLNFHTTFV--GPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEVVRAAQIRGPFGSRSPSRLLDAWPRVAPQGISSLFSSLKVVRLLRLGRVARKLDHYIEY--------GAAVLVLLVCVFGLAAHWLACIWYSIGDYEVIDEATNLIRKHSWLYQLGETIGTPYHFNGTQWEGGPSKDAVYISSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLHICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQTHHCAPGDLIYHAGESVDTLCFVVSGSLEV-IQDDEVVAILGKGDVFGDVFWKERVIAPSCANVRALTYCDLHVIRRDALVKVLDFYMAFANSFSRNLILTYNVRGL--LIFRKISDVKREEEELQKLKNEAPLDIPPDHPVRKLFQR 722          

Query:  303 LQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIG----LVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLI--PMLQDFPKESW------VLKCELLNEKWTNQ----------YTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQ-GKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRM---ASILARTHCSIYSLDRMSFMRVLEDYP 1775
            LQK   NK K        ++NN     +FG K +L + K+    ++ +I+     F+  W+ ++++      V +P  + F     NI           + +ILF++DI++N RT  +  S   +++   R I   Y+ TWF  D ++++PFD +Y             +     L+     +     L  +  L RY Q+   +L +         ++F+  LL+HW AC+ + I    ++   + SW       L  +L     TN           Y   L+ A+S + S+G+G     + +E   ++ ++L G   +A+  G+  A+I    + +  Y+ + K +K+++   +LPK+++Q+++ Y++  +      +   +L++  + LR +I  +  ++++  + IF +A +  +  + + +K     PG  +I++G      YF+  G ++V  K+  ++A L  G   G   L +K + +   A + A T+C +  +       VL+ YP
Sbjct:   15 LQKQDKNKLK--------INNN-----VFGEKPSLPEYKVAAIQKSRFILLHYGTFKAGWDLLILLATFYVAVTVPYNVCFSETVENISDPRSTAVVDISVEILFIIDILLNFRTTYVSKS--GQVVYDGRSICVHYVTTWFFIDLIAALPFDLLY-----------AFNVSVTTLVHLLKTVRLLRLLRLLQNLDRYSQYSTVVLTL---------LMFMFGLLAHWMACIWYKIGRAEIEINDRHSWDIGWLHELGKKLETPFHTNNTGGGPSTRSAYIASLYFALSSLTSVGFGNVSANTDAEKIFSVCAMLIGALMHAVVFGNVTAIIQRMYSRRSQYHTRTKDLKDFIRVHRLPKQLKQRMLEYFQTTWSVNNGIDTHELLKDFPDELRADIAMHMNKEIL-QLAIFESASRGCLRSLSLSIKPSFCAPGEFLIRQGDALQAFYFVCSGSMEV-LKDDMVLAILGKGDLIGSD-LSSKDQVLKTNADVKALTYCDLQCIHLRGLYDVLDLYP 493          

Query:  852 RLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGK-IFNEGNILEELSECLREEI---INYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVT--TKEKEIIASLSNGGFFGEICLLT---KSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVA 1805
            RL++ +    +   L+ I++ +  +       +L+  L H NAC  + +  ++      WV   +        +Y  C + A+  +++IG G   P++  E    + +   GV   ++ +G    +I +    +  Y         YM    + + ++ ++  +YEY +  + + +E  +LE+L   +R EI   +NY    +V  V +F+  D+  I D+L+RLK  VY PG+ + K+G +G +MY I  G V V      K +  +L  G  FGEI LL     +RR A+++A    +++ LD+     +L  YP   + L K A
Sbjct:  163 RLIKYYAFFEFNDRLEAIMSKAYIYRVIRTTGYLLFSL-HLNACFYYFVSDMEGLGSTRWVYNGK------GYRYIRCYYWAVKTLITIG-GLPEPSNLIEIVFQLSNYFLGVFVVSIMIGQMGDVIGAATAGQNYYRTCMDNTLSYMNMYHISRAVQNRVRMWYEYTWASQGMLDESELLEKLPIKMRLEIAIDVNYT---IVNKVALFKGCDRQMIYDMLLRLKSVVYLPGDFVCKKGELGREMYIIKAGEVQVVGGPDNKIVFVTLRTGSVFGEISLLAVGGGNRRTANVMAHGFANLFILDKRDLNEILRIYPESEKLLRKKA 478          

Query: 1443 DLVAAVPIFRNA---DQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVL 1763
            DL+ ++P+ ++    D+  + D L     ++YQPG  II+EG  G   Y I  G VDV+ K + +I  L +  +FGE+ LL    R A++ A     + +L +  F R+L
Sbjct:  295 DLLKSMPVLKSLTTYDRAKLADAL---DTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLL 401          

Query: 1536 GNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVL 1763
            G  IIK+G  G   Y +  G VD    + ++ +S   G  FGE+ L+  S R A+++A + C +++LDR++F ++L
Sbjct:  208 GATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSS-GPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKIL 282          

Query:  336 KLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGK 1832
            +L+S+++  +NK  +K+FG+K A+  E+LR  + A W+IHP S FR  W+  +++ L+I++  LP+++SFF ++ +   + F+   D  FLLDI++N RTGVLV+   ++ IL P+ I  RY+KTWF  D +SS+P DYI   + +S+   +++ A + L +LR  K+LG L+LLR+ RLVRY+Q  +EILN++   +   N++ +++L++HWN CLQFL+P LQDFP+ SWV    L++  W  QY W LF A+SHML IGYGRYPP + +E W+T  S+LTG T YA+F+ +    I   D+  R Y EK +QI+EYM+Y +LP E+R ++  YY++RYQG++F+E  IL E+S+ LRE+IINYNCRDLV +VP F  A+ +F++ ++ RL +EVY  G++I++EG +GT+MYF+ +GVV VT   K     L +G +FGEICLLT +RR AS+ A+T C ++ L+   F  V++++P MR  +E VA +RL  +GK
Sbjct:    4 RLKSWLKPMDNKMNMKVFGSKRAMKDEQLRY-SRAGWVIHPTSIFRLYWDMWVLLLLLINLFALPVLISFFADNVSARWIAFNAVSDTAFLLDILLNFRTGVLVHGSPNKFILDPKIIAKRYLKTWFFIDLISSLPIDYIVEAATQSST-KSLIGATRTLKLLRFAKLLGLLKLLRLSRLVRYVQQYEEILNVTRSVIRFINLVSIILLIAHWNGCLQFLVPYLQDFPETSWVSIHNLMDNDWWEQYCWSLFKAMSHMLCIGYGRYPPQNIAEVWVTTFSMLTGATFYAMFIAYCINFIQQLDSPGRNYREKIQQIEEYMSYRRLPVELRDRMTKYYDHRYQGRMFDEEKILHEISKPLREQIINYNCRDLVQSVPFFTEAEPDFVSAIITRLSFEVYLEGDIIVREGELGTEMYFLREGVVSVTVGGKH-ANELCDGAYFGEICLLTNARRTASVTAKTVCDVFILNAEHFRDVVDEFPTMRILMEIVAEDRLNKMGK 499          

Query:  363 NNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTK-SRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLL 1844
            +NK ALKLFGNK+A+  E+ RQ  +   +IHP S FR+ W+ +++IF+ + V+ LP+ ++F ++D +I  +  +   D+ F++DI +N RTG++  +  +E+IL  + I   Y++ WFI D  SS+PFDY Y ++  +     +L A +AL +L+  K+L  LRLLR+ RLVRY+   +E+LNI+   +    +I  M++LSHWN C+QF +P LQ+FP +SWV    L       QY+W LF A+SHML IGYG YPP + ++ WLT+ S+  G T YA+F+G  ++LI S D+S RL+NEK  Q++EYM Y KLP  +R ++ ++YE+R+  K+F+E  IL ELS+ LRE I+ +N + L+  VP F  A  +FITD++ +LK+EV+  G+ I + G  G KMYFI  G+VD+ T+E  +  SL +G  FGEICLLTK +RR+AS+ A T C +YSL    F  VL+DYP M+  LE+VA ERL  +G  P L
Sbjct:    1 DNKLALKLFGNKAAVMLEQRRQSQQGKGVIHPFSTFRWYWDILLIIFIFMHVLLLPVSIAFLSDDLSIHWLILNGVSDVFFVVDIFLNFRTGIVDPNNQEEVILDKKVISMMYLRGWFIIDLASSLPFDYAYFIASSTTEEQTLLRASRALRILKLAKLLSLLRLLRVSRLVRYMTRFEELLNIAKGQLRIMKLICCMLVLSHWNGCIQFFVPYLQEFPDDSWVSTSNLKTASPGEQYSWSLFRALSHMLCIGYGHYPPQNLTDLWLTVCSMTAGATFYAVFIGIMSSLIMSIDSSGRLFNEKLNQVEEYMRYRKLPLRIRLQVQDFYEHRFHHKLFDEDAILTELSKNLRETILVHNIKPLLTTVPFFSGASISFITDIVTKLKFEVFLNGDYICRSGHRGDKMYFIQKGIVDILTREGALATSLGDGSHFGEICLLTKEARRVASVRAATTCDVYSLSATHFHEVLQDYPEMKSVLEEVAKERLSRLGLKPKL 495          

Query:  588 ACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTW-FIFDFVSSVPFD--YIYLLSYRSNGLNNILSAGKALLMLRRVKILGTL-RLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWV---LKCELLNEK---WTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIF-NEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKE-KEIIASLSNGGFFGEICLLTKS----RRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERL 1817
            +CD++++ DI+++MRTG L    +       RR    Y+ T+ F  D  + +P D  YI++    +  +N IL   +    L R +   T   ++R+  LV++I                       +L+ HWNAC+ F++     F  + WV   ++ E+LN      +  Y +  + +   + +IG    PP S  E  +  +  L GV  +A  VG+   +I + + ++  +  K   IK YM + K+P+ ++++++ +++Y +  K   +E  IL  L + LR EI      D +  V IF++ +  F+ ++++RL+ +++ PG+ + ++G +G +MY +  G ++V ++   +I A L  G +FGEI +L+ S    RR AS+ +  +  ++ L +   M VL++YP ++  +EK+A E+L
Sbjct:   46 SCDLIYIADILVSMRTGFLEEGILQTCSTKMRR---HYLHTYEFYLDAGALIPLDIAYIFIEHEPAFRINRILKFHRFWHFLDRTESRTTFPNVVRLASLVQFI-----------------------LLIIHWNACIYFIVSREIGFGSDVWVYPGVRQEILNSSENTISRMYIYSFYWSTLTLTTIGEVP-PPYSEVEYIIVTLDYLIGVLLFATIVGNVGNIITNLNATRLDFQNKMDGIKAYMRFHKIPQHLQRRVIKWFDYLWTYKKHPDEEEILLSLPDKLRAEIAINVHLDSLRKVAIFQDCEAGFLCELVLRLRSQLFSPGDYVCRKGEVGREMYIVNRGKLEVVSEHGTKIYAVLEAGSYFGEISVLSMSSAGNRRTASVRSVGYTELFCLAKNDLMEVLDEYPNIKEKIEKIAKEKL 444          

Query:  447 IIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNED---------------ANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNI-LSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFL---MILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTN-----------QYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQ-GKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRM------ASILARTHCSIYSLDRMSFMRVLEDYPAMR 1784
            II   S F+  W+ V+++F+I +  E+P   +F                   +   L   +   D+LF++DI IN R+   V    DE+I++P++I   Y K+WF+ D +S++PF+  +++ +R +G++N  +S     L    + +L T RLLR+ R+VR      E         G   II L    +L++HW AC+   I   Q     SW+ K    ++  ++           +Y   L+  ++ + S+G+G   P + +E   +I+ ++ G   YA   G+  A+I    +    +    + I++++ + K+P+ +R  +  Y+ + +   K  +   +L+   E L+ +I  +  + L A    F+ A +  +  +  R     + PG  +IK+G    K+YFI  G V+V  K+      L  G      C  T  + +      AS+L +T+C I+ +D    + VL  Y   R
Sbjct:    1 IIRHDSIFKAVWDWVILVFVIYTAFEIPFSATFLLPQELSRMKSSSRFAALVSGSPLAICNLCVDLLFVVDIPINFRS-TYVREGTDELIVNPKKIALNYFKSWFLIDLLSAIPFE--FMVDHRKDGVSNQGVSMPLTGLATTLMGLLKTARLLRLVRIVRKFDRYSE--------YGQAVIILLTCFFLLVAHWLACIWHAIGQAQLGDHNSWIEKLSRHSQHVSSGNVTHTPGLQTRYITALYFTMTSLSSVGFGNVSPNTNAEKVFSILVMIVGALMYASIFGNMTAIIQRLYSRTSRHRRNLRIIQDFVRFYKIPRNLRDDLEEYFRHEWSYTKGMDIDTVLKRFPESLQADICVHLHKKLFAECSAFQCASEGCLRALARRFDIRRHLPGQYLIKQGDEVKKLYFIAKGFVEV-LKDGHCELVLGKGDVIS--CDYTSRQSLRTAKANASLLIQTYCQIHVVDWQDLLSVLRVYSKFR 469          

Query:  447 IIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFN-EDANIGL-VFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTW-FIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQ--EILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWV---LKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLT----IISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGK-IFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLT----KSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLE 1796
            ++ P   F F W   + + +I +   L + ++F +  +AN+   +      D +F LD ++  R G L +     +++   ++  +Y  ++ F+ D +S +PFD +YL                       + +L  LR  R+F+  R++      EI +   +      +I  + L+ HW AC+ F++   + F  + W+   L  +L   K + QY + L+ +   M ++G G     +     LT    I++ LTGV  +A  VG+A  +I     S+  Y  K   +KEY+   +LP  ++++++++++Y ++ K   NE  +  +L++  + EI  +   D +  V +F + D  F+ +++++L+  +  PG+ I ++G  G +MY +  G ++V  +++ ++A+LS G  FGEI LL      + R AS+ +     ++ L +     VLE YP  +  +E
Sbjct:    2 VLDPSGTFYFLWLLTVSLGVIYNYWALIVYVAFPSVHEANLKTCIAVDYTFDSIFFLDTLVQFRVGFLEHGV---MVVGCWKLTKKYGCSFGFMLDLISILPFDVLYLY----------------------LGVLPILRFNRLFKAHRFLLFCDRGEIYSGRPKLFNLAKLIHYLFLIIHWVACVYFILSRYEGFGTDEWLHPRLDGQL--SKLSMQYLYSLYRSSVSMTTVGAGVIGTIATPRTELTLCFVIVTYLTGVLIFATIVGNAGDMIVEMRRSRERYLRKLNGMKEYIEAYQLPAHLKKRVIHWFDYLWRHKRDMNEQELFHKLNDNFKAEIAIHVNLDTLIRVEMFHDCDPGFLHELVLKLRPVICSPGDFICRQGEKGREMYIVNKGSLEVLDEKETVLATLSAGSHFGEISLLNMKGIGNLRTASVRSVGFSDLFQLSKTDLEEVLEFYPQAKEQME 441          

Query:  288 INDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + ++   + T    + +  S +Q   NK +L++FG++ A++KE+ R ++  NWIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++      EIIL P++I  +Y+K+WF+ DFVSS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQFL+PMLQDFP + WV    ++N+ W+  Y++ LF A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +ILEEL+E LREEIIN+NCR LVA++P+F NAD NF+T +L +L++EV+QPG+ II+EGTIG KMYFI  GVV + TK   I   L +G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +L+ K Q
Sbjct:  206 VPEDGDSRGTQTYMQRQFSSLLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVISDTFFLMDLVLNFRTGIVFEDNT-EIILDPKKIKMKYLKSWFVVDFVSSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSLNNMVNDTWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIIGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIINFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSILTK-GNISMKLMDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQ 731          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  + +Q   NK +L++FG++ A++KE+ R +T   WIIHP S FRF W+ +M+I ++ +++ +P+ ++FF+E      + F+ A D +FL+D+++N RTG+ VN    EIIL P+ I   Y+K+WF+ DF+SS+P DYI+L+  +  G ++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V  FN+I +M+LL HW+ CLQ+L+P+LQDFP + WV    ++N  W  QY++ LF A+SHML IGYG   P S S+ W+T++S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP ++RQKI +YYE+RYQGKIF+E NIL EL++ L+EEI+N+NCR LVA +P+F NAD NF+T +L +LK+EV+QP + II+EGT+G KMYFI  GV  V TK  KE+   L++G +FGEICLLTK RR AS+ A T+C ++SL    F  VLE+YP MRR  E VA +RL+ IG KN LLL+K Q
Sbjct:   71 QRQFGAMMQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTTWLVFNVASDTIFLVDLVMNFRTGI-VNEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEK--GFDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQYLVPLLQDFPPDCWVSLNGMVNVSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQKIHDYYEHRYQGKIFDEDNILSELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPYDYIIREGTVGKKMYFIQHGVASVITKFNKEM--KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSLLLQKFQ 582          

Query:  291 NDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            +DE L +  F     +L + +Q   NK +L++FG++ A+++E+ R ++   WIIHP S FRF W+  M++ ++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG++      EIIL P++I  +Y+++WF+ DF+SS+P DYI+L+   +   ++     +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV K +++N+ W  QY++ LF A+SHML IGYG YPP   ++ WLTI+S++ G TCYA+FVGHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQ+I +YYE+RYQGK+F+E +IL EL+E LREEIIN+NCR LVA++P+F NAD NF+T +L +LK+EV+QPG+ II+EGTIG KMYFI  GVV V TK  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL   +F  VLE+YP MRR  E VA +RL+ IG KN +L  K Q
Sbjct:  167 DDERLYQAGF--IHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNT-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLV-VETRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKET--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILQHKVQ 689          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNN-ILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGT----FNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-KNPLLLKKQQ 1859
            + +  S +Q   NK +L+++G++ A+++E+ R ++  NWIIHP S FRF W+  M++F++ +++ +P+ ++FF ++     + F+   D  FL+D+++N RTG+++    D IIL P+ I  +Y+KTWFI DF+SS+P DYI+L+  +  G+++ +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI +++          FN+I +M+LL HW+ CLQFL+PMLQ+FP + WV   ++ N+ W+  Y++ +F A+SHML IGYGR  P S S+ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP + RQKI +YYE+RYQGK+F+E +IL ELSE LREEI+N+NCR LVA++P+F NA+ NF+T +L +L++EV+QP + II+EGTIG KMYFI  GV  V TK   +   LS+G +FGEICLLT+ RR AS+ A T+C +YSL    F  VLE+YP MRR  E VA +RL+ IG KN +L+ K Q
Sbjct:  336 QRQFSSMLQPGVNKFSLRMYGSQKAVEREQERVKSAGNWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIIIEDNSD-IILDPKTIKTKYLKTWFIVDFISSIPVDYIFLIVEK--GIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIGMMLLLCHWDGCLQFLVPMLQEFPSDCWVSLNKMENDTWSELYSFAVFKAMSHMLCIGYGRQAPESLSDIWLTMLSMIVGATCYAVFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILGELSEPLREEIVNFNCRKLVASMPLFANAEPNFVTAMLTKLRFEVFQPHDYIIREGTIGKKMYFIQHGVCSVITK-GTLAMKLSDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQ 847          

Query:  330 KEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEIL----NISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTK-EKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIG-------KNPLLLKK 1853
            + +  + +Q   NK +L++FG+  A+  E+ R ++   WIIHP S FRF W+ +M+I ++ +++ LP+ ++FF ++     + F+   D LF++D+++N RTG+ V     EI+L PR I   Y+K+WF+ DFVSS+P DYI+L+    +  + +    +AL ++R  KIL  LRLLR+ RL+RYI   +EI     ++++  V   N+I +M+LL HW+ CLQFL+PMLQDFP + WV K  ++N+ W  QY++ LF A+SHML IGYG   P   ++ WLT++S++ G TCYA+F+GHA ALI S D+S+R Y EK+KQ+++YM++ KLP +MRQKI  YYE+R+QGK+F+E NIL ELSE L+EEI+++NCR LVA +P+F NAD NF+T VL +L++EV+QP + II+EGT+G KMYFI  G V V T+  KE    LS+G +FGEICLLT+ RR AS+ A T+C +YSL   SF  VLE++P MRR  E VA +RL+ IG       KN +LL+K
Sbjct:   53 QRQFGAMLQPGVNKFSLRMFGSHKAVAMEQERLKSAGAWIIHPYSDFRFYWDLLMLILMMGNLIVLPVGITFFRDENTASWIIFNVVSDTLFMVDLVLNFRTGI-VKEDNTEILLDPREIRQNYLKSWFLVDFVSSIPVDYIFLMMDSLD--SEVYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSKNLMVNDTWGVQYSYALFKAMSHMLCIGYGAQAPEGMTDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHEYYEHRFQGKMFDEENILGELSEPLKEEIVSFNCRSLVANMPLFANADPNFVTAVLTKLRFEVFQPADFIIREGTVGRKMYFIQHGRVSVLTRGNKET--KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDSFNEVLEEHPMMRRAFETVAVDRLDRIGNKHFAGRKNSMLLRK 567          

Query:  129 MNRFNRMGSSQKLPTSFPYLDGPIDESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAES 1901
            MNRFNRMGSSQKLPTSFPYLDGPI+ESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCA DILFLLDIIINMRTGVLVNSYVDEIILSPRRIFF YMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNI+SAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCA S
Sbjct:    1 MNRFNRMGSSQKLPTSFPYLDGPIEESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCASDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFHYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNIISAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAVS 591          

Query:  129 MNRFNRMGSSQKLPTSFPYLDGPIDESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTG---------VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAES 1901
            MNRFNRMGSSQKLPTSFPYLDGPI+ESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCA DILFLLDIIINMRT          VLVNSYVDEIILSPRRIFF YMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNI+SAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCA S
Sbjct:    1 MNRFNRMGSSQKLPTSFPYLDGPIEESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCASDILFLLDIIINMRTDRTLINVEPRVLVNSYVDEIILSPRRIFFHYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNIISAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAVS 600          

Query:  147 MGSSQKLPTSFPYLDGPIDESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAES 1901
            MGSSQKLPTSFPYLDGPI+ESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCA DILFLLDIIINMRTGVLVNSYVDEIILSPRRIFF YMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNI+SAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCA S
Sbjct:    1 MGSSQKLPTSFPYLDGPIEESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCASDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFHYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNIISAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAVS 585          

Query:  147 MGSSQKLPTSFPYLDGPIDESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTG---------VLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAES 1901
            MGSSQKLPTSFPYLDGPI+ESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCA DILFLLDIIINMRT          VLVNSYVDEIILSPRRIFF YMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNI+SAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCA S
Sbjct:    1 MGSSQKLPTSFPYLDGPIEESLSTDTDTRISDSKPDLSYNCANFSLEINDESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCASDILFLLDIIINMRTDRTLINVEPRVLVNSYVDEIILSPRRIFFHYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNIISAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDESSEKYCAVS 594          

Query:  294 DESLQKNTFNKAKEKLRSFIQLSNNKQALKLFGNKSALDKEKLRQRTEANWIIHPCSGFRFCWNSVMVIFLIISVVELPIVLSFFNEDANIGLVFFHCACDILFLLDIIINMRTGVLVNSYVDEIILSPRRIFFRYMKTWFIFDFVSSVPFDYIYLLSYRSNGLNNILSAGKALLMLRRVKILGTLRLLRIFRLVRYIQHLQEILNISNRFVGTFNIIFLMILLSHWNACLQFLIPMLQDFPKESWVLKCELLNEKWTNQYTWCLFNAISHMLSIGYGRYPPTSPSEAWLTIISVLTGVTCYALFVGHAAALIYSFDTSKRLYNEKFKQIKEYMAYMKLPKEMRQKIVNYYEYRYQGKIFNEGNILEELSECLREEIINYNCRDLVAAVPIFRNADQNFITDVLVRLKYEVYQPGNLIIKEGTIGTKMYFILDGVVDVTTKEKEIIASLSNGGFFGEICLLTKSRRMASILARTHCSIYSLDRMSFMRVLEDYPAMRRYLEKVAAERLEAIGKNPLLLKKQQTLQDE 1874
            D++ ++ T +  KE+  SF Q S+NK A+KLFGNK+AL+KEK RQ+ +  W+IHPCS FRF W+ +M+  LI +++ LP+ +SFFN+D ++  + F+C  D +FLLDI +N RTGV+ N Y DEIIL P++I   Y+K+WF  DF+SS+P DYI+L+  +    N I+ AG+AL +LR  K+L  LRLLR+ RLVRY+   +E+LN++++F+G FN++ LM+LL HWNACLQFLIPML+D+P +SWV+KC+L    W +QYTW LF A+SHMLSIGYGRYPPTS  EAW+TI+S++TG TCYALFVGHAAALI SFDTSKRLY EKFKQ++EYMAY KLP+ +RQ+I NYYE+RYQGK+FNE +IL ELSECLRE+IINYNCR LVAAVP F  ADQNF+++V+V+L+YEV+QPG+LIIKEG +GT+MYFI +G+VD+ TKE E+  SLS+G +FGEICLLT +RR+AS+ A T+C++YSLDR SF+ VLE+YP MRR +E VAAERL  IG+NPLL+  +Q L ++
Sbjct:  244 DDANRQTTSSYLKEQFLSFFQPSDNKLAMKLFGNKNALNKEKRRQQQQGKWVIHPCSNFRFYWDLLMLSLLIANLIILPVAISFFNDDLSLKWIIFNCISDTIFLLDIFVNFRTGVITNDYADEIILVPKQIAQNYLKSWFALDFISSIPLDYIFLILNKKEYFNQIMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEELLNVASKFIGIFNLVLLMLLLGHWNACLQFLIPMLRDYPSDSWVIKCKLKEAYWFDQYTWALFKAMSHMLSIGYGRYPPTSICEAWITIVSMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRGLRQRIANYYEHRYQGKMFNELDILNELSECLREQIINYNCRALVAAVPFFTYADQNFVSEVVVKLQYEVFQPGDLIIKEGNLGTRMYFIQEGIVDIITKEGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNVYSLDRDSFLSVLENYPLMRRTMESVAAERLIKIGQNPLLVSTRQDLTED 770