centriolin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012954 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of centriolin vs. Ensembl Human
Match: CNTRL (centriolin [Source:HGNC Symbol;Acc:HGNC:1858]) HSP 1 Score: 185.267 bits (469), Expect = 2.114e-49 Identity = 122/327 (37.31%), Postives = 191/327 (58.41%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L IK LNL K G KK +YIE+L+ + VL++ ++ I KIEKLDKL LREL LS NKI +++G+EN+ NL+ L++ GN++ IP W ++ K L +N N S+++ISKL L+DL+ L + ENPV + HY + + L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q + ++ QD+ K L ++ QK + E++K + RACQK YELEQ++AF KIDAKF+ L+ + SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELT---RACQKQYELEQELAFYKIDAKFEPLNYY---------PSEYAEIDKAPDESPYIGKSRY 393
BLAST of centriolin vs. Ensembl Human
Match: CNTRL (centriolin [Source:HGNC Symbol;Acc:HGNC:1858]) HSP 1 Score: 187.578 bits (475), Expect = 1.246e-46 Identity = 123/327 (37.61%), Postives = 192/327 (58.72%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L IK LNL K G KK +YIE+L+ + VL++ ++ I KIEKLDKL LREL LS NKI +++G+EN+ NL+ L++ GN++ IP W ++ K L +N N S+++ISKL L+DL+ L + ENPV + HY + + L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q + ++ QD+ K L ++ QK + E++K + RACQK YELEQ++AF KIDAKF+ L+ + P SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELT---RACQKQYELEQELAFYKIDAKFEPLNYY--P-------SEYAEIDKAPDESPYIGKSRY 393 HSP 2 Score: 105.145 bits (261), Expect = 1.414e-21 Identity = 211/941 (22.42%), Postives = 435/941 (46.23%), Query Frame = 1
Query: 3397 SAPSNNPQFVQQQAMPPNNSPLPGATYI---PNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKHKSSWKLKQKF----KSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQ------DLLN-NISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSR---QVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNE----KKELESNLKILRKQE--SQVHET-LTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIF--DLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIF--ELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKR---------------------VAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P + +P N+ PL T + P P ++ P ++P+ + G L CNVPEHH LE+ ++ +H S K ++++ K SEK M E++H +DL E L ++++L+ T Q D ++ N+ SL E E +SL H + DEI ++ + +++ EL AD L ++ + +E+T + K DA+++ + + EELE++++E ++ L KA +L +Q + L K+ EE++ +I I+ KD++FQ ++++ + +L L+ D+ MA +Q+L E + LL R EL +LK++V Q+ + ++ +G + + + + +++ Q RL + +E+ RE L LE L +K +L I + + +K+ I+K+E++ V+ ++ K + ++I ML+++ +L + ++ R+ +LE+ ++ +E + L +++ EI+ +Q + D +R+ + +++ + LSKEK LQ + +K+L ++L E S++ ++ L LE V + + EL++++ +K S L +++ +QL E + + S++E L ++ + ++ + Q L E +LQ I F++ E + ++++ L EI + +++KL+++++ LQ E++KLE + QL+ E+T++ L+ +K+ L + ++ E++ + LE+ + Q + EQ+ + S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +LNQ + +Y L+ ++
Sbjct: 1255 PVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGP--PPPNFSIPFIPM--------GVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEM-------EELHHNIDDL----------LQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEI---------EKSLKH----HEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSL---LEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLS-------LHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEI--EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV--LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMA 2141
BLAST of centriolin vs. Ensembl Human
Match: CNTRL (centriolin [Source:HGNC Symbol;Acc:HGNC:1858]) HSP 1 Score: 187.578 bits (475), Expect = 1.246e-46 Identity = 123/327 (37.61%), Postives = 192/327 (58.72%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L IK LNL K G KK +YIE+L+ + VL++ ++ I KIEKLDKL LREL LS NKI +++G+EN+ NL+ L++ GN++ IP W ++ K L +N N S+++ISKL L+DL+ L + ENPV + HY + + L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q + ++ QD+ K L ++ QK + E++K + RACQK YELEQ++AF KIDAKF+ L+ + P SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELT---RACQKQYELEQELAFYKIDAKFEPLNYY--P-------SEYAEIDKAPDESPYIGKSRY 393 HSP 2 Score: 105.145 bits (261), Expect = 1.414e-21 Identity = 211/941 (22.42%), Postives = 435/941 (46.23%), Query Frame = 1
Query: 3397 SAPSNNPQFVQQQAMPPNNSPLPGATYI---PNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKHKSSWKLKQKF----KSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQ------DLLN-NISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSR---QVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNE----KKELESNLKILRKQE--SQVHET-LTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIF--DLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIF--ELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKR---------------------VAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P + +P N+ PL T + P P ++ P ++P+ + G L CNVPEHH LE+ ++ +H S K ++++ K SEK M E++H +DL E L ++++L+ T Q D ++ N+ SL E E +SL H + DEI ++ + +++ EL AD L ++ + +E+T + K DA+++ + + EELE++++E ++ L KA +L +Q + L K+ EE++ +I I+ KD++FQ ++++ + +L L+ D+ MA +Q+L E + LL R EL +LK++V Q+ + ++ +G + + + + +++ Q RL + +E+ RE L LE L +K +L I + + +K+ I+K+E++ V+ ++ K + ++I ML+++ +L + ++ R+ +LE+ ++ +E + L +++ EI+ +Q + D +R+ + +++ + LSKEK LQ + +K+L ++L E S++ ++ L LE V + + EL++++ +K S L +++ +QL E + + S++E L ++ + ++ + Q L E +LQ I F++ E + ++++ L EI + +++KL+++++ LQ E++KLE + QL+ E+T++ L+ +K+ L + ++ E++ + LE+ + Q + EQ+ + S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +LNQ + +Y L+ ++
Sbjct: 1255 PVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGP--PPPNFSIPFIPM--------GVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEM-------EELHHNIDDL----------LQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEI---------EKSLKH----HEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSL---LEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLS-------LHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEI--EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV--LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMA 2141
BLAST of centriolin vs. Ensembl Human
Match: CNTRL (centriolin [Source:HGNC Symbol;Acc:HGNC:1858]) HSP 1 Score: 105.531 bits (262), Expect = 1.189e-21 Identity = 210/935 (22.46%), Postives = 433/935 (46.31%), Query Frame = 1
Query: 3397 SAPSNNPQFVQQQAMPPNNSPLPGATYI---PNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKHKSSWKLKQKF----KSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTN-EIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSR---QVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNE----KKELESNLKILRKQE--SQVHET-LTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIF--DLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIF--ELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKR---------------------VAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P + +P N+ PL T + P P ++ P ++P+ + G L CNVPEHH LE+ ++ +H S K ++++ K SEK M E++H +DL +Q K E+ L+ + + K + N+ SL E E +SL H + DEI ++ + +++ EL AD L ++ + +E+T + K DA+++ + + EELE++++E ++ L KA +L +Q + L K+ EE++ +I I+ KD++FQ ++++ + +L L+ D+ MA +Q+L E + LL R EL +LK++V Q+ + ++ +G + + + + +++ Q RL + +E+ RE L LE L +K +L I + + +K+ I+K+E++ V+ ++ K + ++I ML+++ +L + ++ R+ +LE+ ++ +E + L +++ EI+ +Q + D +R+ + +++ + LSKEK LQ + +K+L ++L E S++ ++ L LE V + + EL++++ +K S L +++ +QL E + + S++E L ++ + ++ + Q L E +LQ I F++ E + ++++ L EI + +++KL+++++ LQ E++KLE + QL+ E+T++ L+ +K+ L + ++ E++ + LE+ + Q + EQ+ + S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +LNQ + +Y L+ ++
Sbjct: 703 PVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGP--PPPNFSIPFIPM--------GVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEM-------EELHHNIDDL----LQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEI---------EKSLKH----HEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSL---LEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLS-------LHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEI--EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV--LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMA 1589
BLAST of centriolin vs. Ensembl Human
Match: PPP1R7 (protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295]) HSP 1 Score: 66.6254 bits (161), Expect = 1.595e-10 Identity = 52/159 (32.70%), Postives = 87/159 (54.72%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I+ I + D L ++ L L G KI +++LD L N+TVLS++ + + KIE L L NLRELYLS N I ++GLEN L +LD+ N++ I + +LT++ + N+ +S ++ +L + L + + NP+ YR +++ L
Sbjct: 155 IRAIENIDTLTNLESLFL----GKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIEN-----ISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLAL 304 HSP 2 Score: 52.7582 bits (125), Expect = 3.906e-6 Identity = 33/97 (34.02%), Postives = 61/97 (62.89%), Query Frame = 1
Query: 157 FIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSI 447
IK I + + L +++L+L D +I+ IE+L+ L + +L I F+ + IE +DKL L++L+L NKI +++ L NL L++L++ N++ +I
Sbjct: 66 LIKCIENLEELQSLRELDL----YDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAI 158
BLAST of centriolin vs. Ensembl Celegans
Match: sds-22 (Protein phosphatase 1 regulatory subunit SDS22 homolog [Source:UniProtKB/Swiss-Prot;Acc:P45969]) HSP 1 Score: 60.4622 bits (145), Expect = 5.645e-9 Identity = 54/163 (33.13%), Postives = 85/163 (52.15%), Query Frame = 1
Query: 190 DRIKKL-------NLD-CGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAA--IAHYRLYIVMRLKYLLILD 648
+RIKK+ NLD G KIR +E ++ L ++VLS+ + I KIE +++L NL+ELYLS+ + + G+E L NL +LDV N++ + R + L + N +S EI +L LK L + + NP YR ++M L + +D
Sbjct: 157 NRIKKIENIGHLVNLDELFIGKNKIRQLEGVETLQKLSVLSLPGNRIVKIENVEQLNNLKELYLSDQGLQDIHGVEPLTNLLLLDVANNEIKTFSG--VERLESLNDFWANDNKVESFSEIEQLSKLKGLQTVYLERNPFYFNDTNQYRRKVMMTLTQVTQID 317
BLAST of centriolin vs. Ensembl Celegans
Match: K10D2.8 (pep chromosome:WBcel235:III:5188726:5190175:1 gene:WBGene00189952.1 transcript:K10D2.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K10D2.8) HSP 1 Score: 58.5362 bits (140), Expect = 2.802e-8 Identity = 39/107 (36.45%), Postives = 63/107 (58.88%), Query Frame = 1
Query: 124 NPPGVRYITEEF--IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQL 438
N PG+R ++ + +K I H L + +LNL+ D +I +E+L+ L N+ L + ++ I KIE L +L NL EL+L NKII ++GLE +K L+ N++
Sbjct: 47 NTPGIRDLSLRWNLLKKIDHFQCLTSLTRLNLN----DNQIEKLENLETLVNLVFLDVSYNRITKIEGLSELINLEELHLVHNKIITIEGLETNTAMKYLEFGDNRI 149 HSP 2 Score: 53.5286 bits (127), Expect = 1.087e-6 Identity = 41/136 (30.15%), Postives = 76/136 (55.88%), Query Frame = 1
Query: 184 HLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAA 591
HL +++L L G +IR IE LD + + LS+ +A++ IE LD L L+ + L++N I ++DGL L NLK LD+ N + + + + K ++ + +N + +++ +L L++L L + NP+ +
Sbjct: 157 HLVNLERLFL----GANQIRKIEGLDGMAQLKELSLPGNALQIIEGLDTLSGLKSISLAQNGIRKIDGLSGLTNLKSLDLNDNIIEKLEN--VEQFKGISSLMIRKNKLNCWQDVRQLKKLENLTVLTMEMNPLYS 286
BLAST of centriolin vs. Ensembl Celegans
Match: C06A8.6 (pep chromosome:WBcel235:II:7772499:7773914:1 gene:WBGene00015516.1 transcript:C06A8.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06A8.6) HSP 1 Score: 53.1434 bits (126), Expect = 1.286e-6 Identity = 37/105 (35.24%), Postives = 60/105 (57.14%), Query Frame = 1
Query: 169 IAHEDHL----DRIKKL-NLDCGKG-------DKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSI 447
+ H +H + IKK+ NLDC D +I +E+LD+L N+ L + F+ I KIE L+KL L+ L+ NKI +++GL+ L L+ L++ N++ I
Sbjct: 53 LTHVEHFSFRWNLIKKIENLDCLTTLTHLEFYDNQITKVENLDSLVNLESLDLSFNRITKIENLEKLTKLKTLFFVHNKITKIEGLDTLTELEYLELGDNRIAKI 157
BLAST of centriolin vs. Ensembl Fly
Match: sds22 (gene:FBgn0028992 transcript:FBtr0083436) HSP 1 Score: 58.5362 bits (140), Expect = 2.939e-8 Identity = 46/127 (36.22%), Postives = 67/127 (52.76%), Query Frame = 1
Query: 226 GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYR 606
G KI IE+LD L N+ +LS++ + I KIE L+KL NLRELY+SEN + ++ L L+ LD+ N+L I + +N N D ++I L K L + + NP+A YR
Sbjct: 179 GKNKIAKIENLDTLVNLEILSLQANRIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLN--HNGVDDWKDIELLKVNKALQTIYLEYNPLAKDVRYR 303 HSP 2 Score: 58.151 bits (139), Expect = 4.051e-8 Identity = 35/99 (35.35%), Postives = 65/99 (65.66%), Query Frame = 1
Query: 235 KIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEIS 531
+I IE+LD L N+T+L + + ++KIE ++ L NLR+L+L +NKI +++ L+ L+NL+IL ++ N++ I + + L ++ S N ++IE +S
Sbjct: 138 RITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIENL--EKLANLRELYVSENGVETIENLS 234 HSP 3 Score: 52.373 bits (124), Expect = 2.746e-6 Identity = 30/73 (41.10%), Postives = 48/73 (65.75%), Query Frame = 1
Query: 229 DKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSI 447
D +I IE+LD+L ++ VL I F+ + KIE LDKL L ++Y N+I +++ L+ L NL +L++ N+L I
Sbjct: 92 DNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKI 164 HSP 4 Score: 51.2174 bits (121), Expect = 6.467e-6 Identity = 49/147 (33.33%), Postives = 77/147 (52.38%), Query Frame = 1
Query: 121 MNPPGVRYITEEFIKIIAHED--HLDRIKKLNLDCGKGDKKIRYIEHLDN---LNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTL 546
MN P T I++I ED ++ I ++ DC + D R IE L+N L I L +R++ I+KIE L L L EL L +N+I +++ L++L +L++LD+ N+L I + + L K+ F N IE + L L
Sbjct: 8 MNEPEAAK-TVSGIQVIPAEDVASIEDIITIDPDCYELDLNHRRIEKLENFEPLTRIERLFLRWNLIKKIENLSSLKTLIELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENL--DKLVKLEKVYFVSNRITQIENLDMLTNL 151
BLAST of centriolin vs. Ensembl Fly
Match: TbCMF46 (gene:FBgn0032163 transcript:FBtr0079898) HSP 1 Score: 56.6102 bits (135), Expect = 2.803e-7 Identity = 48/153 (31.37%), Postives = 82/153 (53.59%), Query Frame = 1
Query: 190 DRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVA-----AIAHYRLYIVMRLKY 633
DRI + L+ K I I+HL + N+T L + + IE IE L+ L L++L LS N I R++ LE L+ L+ L + N++ I + T + L ++ N+ D++E I +L + L L++ NP+A ++ Y + I+ +L Y
Sbjct: 67 DRITTMRLEF----KNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHT--LQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPIAKQPDFPLSLYVIAILPQLNY 213
BLAST of centriolin vs. Ensembl Fly
Match: Ppr-Y (gene:FBgn0046697 transcript:FBtr0346721) HSP 1 Score: 54.6842 bits (130), Expect = 1.004e-6 Identity = 40/130 (30.77%), Postives = 74/130 (56.92%), Query Frame = 1
Query: 247 IEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYL 636
I+HL L N+T L + + IE IE ++ L NL++L LS N I +++ L+ L+NL++L + N++ +I + L I+ N+ D++E I + + +L +++ NP+A ++ L LKY+
Sbjct: 74 IDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIEN--IDMLTMLVIISLGNNLIDTVEGIERFRFMNNLKIINLEGNPIAKRTNFCL-----LKYI 196
BLAST of centriolin vs. Ensembl Zebrafish
Match: lrrc23 (leucine rich repeat containing 23 [Source:ZFIN;Acc:ZDB-GENE-041010-153]) HSP 1 Score: 72.0182 bits (175), Expect = 1.917e-12 Identity = 53/161 (32.92%), Postives = 88/161 (54.66%), Query Frame = 1
Query: 196 IKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXV-SENPVAAIAHYRLYIVMRLKYLLILDNREVLADEK 675
++ LNL G G + ++ ++H NL N+ L +R + +E + + L NLR LYL++N I +L+GLE L L L +R NQL ++ + K L +N N+ S+ + L ++ L V +NP+A YRLY++ +L +L +D V +EK
Sbjct: 151 LETLNL-TGNGIQTMQGLDH-PNLTNLVTLELRGNCLETTDGI-YLPNLRHLYLAQNNIKKLEGLEKLERLITLHLRHNQLETL-DGLSASMKCLEYLNVRGNLISSMRALQTLASVGQTLKALVLLDNPIAKTDDYRLYVISQLPHLERVDKDPVTPEEK 307
BLAST of centriolin vs. Ensembl Zebrafish
Match: ppp1r7 (protein phosphatase 1, regulatory (inhibitor) subunit 7 [Source:NCBI gene;Acc:560323]) HSP 1 Score: 67.781 bits (164), Expect = 4.634e-11 Identity = 56/177 (31.64%), Postives = 87/177 (49.15%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGK------------------GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I IA+ DHL ++ L L + G KI +++LD L+N+TVLSI+ + I K+E L L NLRELYLS N I ++GLEN L LD+ N++ I + +LT + + N ++ ++ +L K L + + NP+ YR I++ L
Sbjct: 161 IASIANLDHLTSLQMLELGSNRIRVIENLDSLSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLVNLRELYLSHNGIEVMEGLENNKKLSTLDIAANRIKKIEN-----ISHLTDLKEFWMNDNQIENWADLDELKNAKGLETVYLERNPLQKDPQYRRKIMLAL 332
BLAST of centriolin vs. Ensembl Zebrafish
Match: lrguk (leucine-rich repeats and guanylate kinase domain containing [Source:ZFIN;Acc:ZDB-GENE-050419-232]) HSP 1 Score: 67.781 bits (164), Expect = 1.269e-10 Identity = 48/161 (29.81%), Postives = 94/161 (58.39%), Query Frame = 1
Query: 247 IEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSR 729
I L+ ++ LS+ + I +I LD L LREL L+ N I +++ L+ L NL++LD+ N++ S+ + ++L +N N+ I+E + L L L ++++ +NPV YR+ ++ L++L++LD + V A+EK A+ +++ L+ +++R
Sbjct: 131 IRGLEKCKRLSHLSLAHNNISRIRGLDHL-PLRELCLAGNMINKIENLQTLHNLQVLDLSCNRIQSL--TGLQNLRFLGTVNLESNLITEIKEAAHLHDLILLREINLLKNPVQDHDDYRIAVIFLLQHLILLDKQTVTAEEKVAAVNKYDP-PLEVVAAR 287
BLAST of centriolin vs. Ensembl Zebrafish
Match: cntrl (centriolin [Source:ZFIN;Acc:ZDB-GENE-120608-3]) HSP 1 Score: 61.2326 bits (147), Expect = 1.624e-8 Identity = 94/494 (19.03%), Postives = 219/494 (44.33%), Query Frame = 1
Query: 3436 AMPPNN----SPLPGATYIPNGFLPQIHNSHSTPI-LNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKF--KSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDE 4896
A PP + +PG +P G ++ P L P + +T + +G+L CNVP H LE + K+ +L+++ ++ SE+ TL ++ L +I L T + L + S L +L H + L E+ ++ + +++ EL AD L + Q +T E + +++A+K ++ E E+EK+++++ L ++ +L +Q E L K + E + + ++ D++FQ ++ ++ RA +L + +L + +Q E + L+ + +L+ + +V+L Q+ L ++ + + ++ +E+ RQ ++++ + + +++ +L+ ++ +L +K +L + + + Q+K++ ++E++ L+S ++K + + M++++ G+L+ V + +L LE+ E
Sbjct: 22 AFPPGSFIYSHSVPG---LPIGASTVLYGPPPDPARLVYGPPPANLTVPLVPSGTLHCNVPGHQDLERDLK-----KAERRLREECADRAHSEQEQHTLQ------------------------DKTAELQQEIKHLRRTVRTLQRHTSGL---------------ESTLSHAEEEQCVLG-EVECLEKTLLKRRAELREADRRLLEADAQLKNTQTKTEENIHHYNEAKKRMEETERELAEIEKRAQDSGKLLVQSKQQLRSLQEEVMTLQKRKEDKERSLHDAEEVLTCHDSKFQDVSRKLERANDRLEIAEKELRETQSMEVKLLQSCREMENSLAQRKTKLDEVNTQVMLQQKELSLLDRKLEQWKREEEVLRVSVEQHRQALLDVLRQGEEDAKLLQQRVQELRVDVHSLAVQKGELDSQLSERKTRLAQLKKDQQQEEETLQSLRSVIKKHKAELARMLEMIQLETGELEDVKLQCNQKLEQLEKSQE 467
BLAST of centriolin vs. Ensembl Zebrafish
Match: cntrl (centriolin [Source:ZFIN;Acc:ZDB-GENE-120608-3]) HSP 1 Score: 61.2326 bits (147), Expect = 1.741e-8 Identity = 97/494 (19.64%), Postives = 219/494 (44.33%), Query Frame = 1
Query: 3436 AMPPNN----SPLPGATYIPNGFLPQIHNSHSTPI-LNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKF--KSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDE 4896
A PP + +PG +P G ++ P L P + +T + +G+L CNVP H LE + K+ +L+++ ++ SE+ TL ++ L +I L T + L + S L E LG + L + K + +RE L AD +LKN++ +T E + +++A+K ++ E E+EK+++++ L ++ +L +Q E L K + E + + ++ D++FQ ++ ++ RA +L + +L + +Q E + L+ + +L+ + +V+L Q+ L ++ + + ++ +E+ RQ ++++ + + +++ +L+ ++ +L +K +L + + + Q+K++ ++E++ L+S ++K + + M++++ G+L+ V + +L LE+ E
Sbjct: 284 AFPPGSFIYSHSVPG---LPIGASTVLYGPPPDPARLVYGPPPANLTVPLVPSGTLHCNVPGHQDLERDLK-----KAERRLREECADRAHSEQEQHTLQ------------------------DKTAELQQEIKHLRRTVRTLQRHTSGLESTLSHAEEEQCV-----LGEVEC----LEKTLLKRRAELREADRRLLEADAQLKNTQT-------KTEENIHHYNEAKKRMEETERELAEIEKRAQDSGKLLVQSKQQLRSLQEEVMTLQKRKEDKERSLHDAEEVLTCHDSKFQDVSRKLERANDRLEIAEKELRETQSMEVKLLQSCREMENSLAQRKTKLDEVNTQVMLQQKELSLLDRKLEQWKREEEVLRVSVEQHRQALLDVLRQGEEDAKLLQQRVQELRVDVHSLAVQKGELDSQLSERKTRLAQLKKDQQQEEETLQSLRSVIKKHKAELARMLEMIQLETGELEDVKLQCNQKLEQLEKSQE 729
BLAST of centriolin vs. Ensembl Xenopus
Match: CNTRL (centriolin [Source:NCBI gene;Acc:100270771]) HSP 1 Score: 171.785 bits (434), Expect = 6.781e-42 Identity = 121/336 (36.01%), Postives = 200/336 (59.52%), Query Frame = 1
Query: 94 FIFQISVILMNPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQF 1098
+ Q + N GVRYITE I+ +++L + LNL K G KK ++IE+L+ + VL++ + IEKIEKL+K LREL L+ NKI +++ E++ NLK L++ GN++ IP W ++ K LT +N N S++++S+L LKDL L +S+NPV+ + HYRLY V L+ L LD + V E++ A E+F EL+++ L + +++E++ + K+ + QD+ + L ++ + K+LE+ +++K+ +LK+K+ +L RACQK YELEQ++AF KIDAKF+ L ++E G+ Y+GK ++
Sbjct: 24 ILIQWVQFICNEVGVRYITESLIQKQTKQENLAYVTSLNLCLAKEGGKKFKFIENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIEHFEHMQNLKKLNLAGNEIEHIPVWVGKKLKSLTALNLKENRISSLQDVSRLKPLKDLTTLSLSDNPVSNLPHYRLYTVFHLRSLNSLDAQPVTNQERQEAHERFNLEELEKLERELEKKISEIDELQNQKAKITGELQNQDELNRSLKQEALQQKKSYKELEQEMETKNEILKQKTVELKRACQKQYELEQELAFYKIDAKFEPLGYFESEVKE----------DVPGESPYIGKARY 349 HSP 2 Score: 110.923 bits (276), Expect = 2.329e-23 Identity = 122/570 (21.40%), Postives = 261/570 (45.79%), Query Frame = 1
Query: 3427 QQQAMPPNNSP----LPGATYIPNGFL--------------PQIHNSHSTPILNTVPYSSI---VTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKS 5073
Q+ MPP S LP T P G + P P+ + Y T + AG L CNVP HH LE+ + KS K + + L+EDI +DL++ + + K+ E+ + + N+ +I +L E E +SL H ++ DEI ++ + +++ EL AD L ++ + +TT+ + K+ A+K+ + EELE++++E + +L KA +L ++Q L + E ++ +I S++++KD+EFQ + ++I L L +D+ + + +Q L E + LL + + L R+ +V Q+ + M+ +G++ + + I+ + ++++ + + A ++E ++K LE+L +K +L + + + ++K+ I ++E + L S++ KL + +H+ M++++ +L + ++ ++ ++E I + +E + L +R E+++ RQ + D + L +++ ++++L +K+
Sbjct: 1171 QRHFMPPAGSVIYTVLPDGTPAPQGTVVYGPPPPSSGRPVAPGTVIYGPPPVGTQIIYGPPPPHFTIPVIPAGVLHCNVPGHHNLENEL------TRLEDIIDHLKSRRHKEKRSKERLQEDI----DDLEHQKEILRKEVEELRVSGQRRKRKNFVD----GHIGTLITELEL---------EKSLQH----HDEIEDEIGCIEKTLLKRRAELREADRLLAEAEAELQSTRAKTTDIIEKYTCAKKHLSTTESDAEELERRAQETARQLVKADQQLRMLQRSACDLEQHRAEQESMLTEINSVVSEKDSEFQALGKKIDTMTESLQKLHADIQVVAAKEANHLQALKEAESLLQEKKAVLERIDEQVYAQQQDIAGMDRLLGQKKEELHLLQDHIDHKKADLKEVLRDGELDVADCRQEIQEVKSLLEDLSAQKGELNAQVSEKKAQLGRLKQEILQEEDNLQTLASQINKLKSELKHVLEMVQLENNELQGLKLQHNQKVDEMENIQTTLLEGKLELENLQRTSQRLNGEVERQRQVLEKDHREMELLMTQMHTLQENVASLGSDKA 1713
BLAST of centriolin vs. Ensembl Xenopus
Match: CNTRL (centriolin [Source:NCBI gene;Acc:100270771]) HSP 1 Score: 170.629 bits (431), Expect = 1.823e-41 Identity = 120/326 (36.81%), Postives = 197/326 (60.43%), Query Frame = 1
Query: 124 NPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQF 1098
N GVRYITE I+ +++L + LNL K G KK ++IE+L+ + VL++ + IEKIEKL+K LREL L+ NKI +++ E++ NLK L++ GN++ IP W ++ K LT +N N S++++S+L LKDL L +S+NPV+ + HYRLY V L+ L LD + V E++ A E+F EL+++ L + +++E++ + K+ + QD+ + L ++ + K+LE+ +++K+ +LK+K+ +L RACQK YELEQ++AF KIDAKF+ L ++E G+ Y+GK ++
Sbjct: 45 NEVGVRYITESLIQKQTKQENLAYVTSLNLCLAKEGGKKFKFIENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIEHFEHMQNLKKLNLAGNEIEHIPVWVGKKLKSLTALNLKENRISSLQDVSRLKPLKDLTTLSLSDNPVSNLPHYRLYTVFHLRSLNSLDAQPVTNQERQEAHERFNLEELEKLERELEKKISEIDELQNQKAKITGELQNQDELNRSLKQEALQQKKSYKELEQEMETKNEILKQKTVELKRACQKQYELEQELAFYKIDAKFEPLGYFESEVKE----------DVPGESPYIGKARY 360 HSP 2 Score: 123.25 bits (308), Expect = 4.306e-27 Identity = 197/928 (21.23%), Postives = 417/928 (44.94%), Query Frame = 1
Query: 3427 QQQAMPPNNSP----LPGATYIPNGFL--------------PQIHNSHSTPILNTVPYSSI---VTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKR-----DELKTQSNS-------VSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDL---QNNVSKEDNKLEKILKNSSFELAQLKSE---ITEKLENLEASGTKLHQLKK-DAAIKE---FTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQN--------------HQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRI 6039
Q+ MPP S LP T P G + P P+ + Y T + AG L CNVP HH LE+ + KS K + + L+EDI +DL++ + + K+ E+ + + N+ +I +L E E +SL H ++ DEI ++ + +++ EL AD L ++ + +TT+ + K+ A+K+ + EELE++++E + +L KA +L ++Q L + E ++ +I S++++KD+EFQ + ++I L L +D+ + + +Q L E + LL + + L R+ +V Q+ + M+ +G++ + + I+ + ++++ + + A ++E ++K LE+L +K +L + + + ++K+ I ++E + L S++ KL + +H+ M++++ +L + ++ ++ ++E I + +E + L +R E+++ RQ + D + L +++ ++++L +K+ ++ ++LE L +Q +TL A E + + EK+ SE IKR D+L Q +S V +Q+ + EL +K+ L ++R + + + E LQ I ++ + L + R++++ + L + I +K E++ ++ + DL + + + KL++ + +ELA K+ + K+ LE +L Q +K AA++E T ++ E E+ ++++ + ++E + LA+ R+N + E + +E + + + K++ +E+ A D RA L +L Q + ++ +LRN++
Sbjct: 1145 QRHFMPPAGSVIYTVLPDGTPAPQGTVVYGPPPPSSGRPVAPGTVIYGPPPVGTQIIYGPPPPHFTIPVIPAGVLHCNVPGHHNLENELTR------LEDIIDHLKSRRHKEKRSKERLQEDI----DDLEHQKEILRKEVEELRVSGQRRKRKNFVD----GHIGTLITELEL---------EKSLQH----HDEIEDEIGCIEKTLLKRRAELREADRLLAEAEAELQSTRAKTTDIIEKYTCAKKHLSTTESDAEELERRAQETARQLVKADQQLRMLQRSACDLEQHRAEQESMLTEINSVVSEKDSEFQALGKKIDTMTESLQKLHADIQVVAAKEANHLQALKEAESLLQEKKAVLERIDEQVYAQQQDIAGMDRLLGQKKEELHLLQDHIDHKKADLKEVLRDGELDVADCRQEIQEVKSLLEDLSAQKGELNAQVSEKKAQLGRLKQEILQEEDNLQTLASQINKLKSELKHVLEMVQLENNELQGLKLQHNQKVDEMENIQTTLLEGKLELENLQRTSQRLNGEVERQRQVLEKDHREMELLMTQMHTLQENVASLGSDKARVEESSQQLEKKL-------AQATKTLAATEENNRAASSNAEKLASE-----IKRLQKEIDQLHKQKHSLRQEGSVVQQQVQDRTDELNLLKDELNDTREGAWLAPQDLRNATRARDEMLREKTTLQAAIEESSARYKSLQDKEARKEQQLSHLQRAIEEKEGEMEKHDQVLRDLDIQEQQLKESTAKLKEHRQALEWELANRKTSLEMLNSKVNALEERALQLQQEEKWSAALEESLRSTRHQLEEKEQALREKASELAEMQKEAEISKADSGRVREQLASQRKNDEKRILLLKDAVKKQRAEYEQAMQEEKQEKNNLQKQLISVEQAAYDNHERAKRLMRELKQLQSEHTVLRNQV 2033
BLAST of centriolin vs. Ensembl Xenopus
Match: CNTRL (centriolin [Source:NCBI gene;Acc:100270771]) HSP 1 Score: 169.088 bits (427), Expect = 5.116e-41 Identity = 119/323 (36.84%), Postives = 196/323 (60.68%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQF 1098
GVRYITE I+ +++L + LNL K G KK ++IE+L+ + VL++ + IEKIEKL+K LREL L+ NKI +++ E++ NLK L++ GN++ IP W ++ K LT +N N S++++S+L LKDL L +S+NPV+ + HYRLY V L+ L LD + V E++ A E+F EL+++ L + +++E++ + K+ + QD+ + L ++ + K+LE+ +++K+ +LK+K+ +L RACQK YELEQ++AF KIDAKF+ L ++E G+ Y+GK ++
Sbjct: 10 GVRYITESLIQKQTKQENLAYVTSLNLCLAKEGGKKFKFIENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIEHFEHMQNLKKLNLAGNEIEHIPVWVGKKLKSLTALNLKENRISSLQDVSRLKPLKDLTTLSLSDNPVSNLPHYRLYTVFHLRSLNSLDAQPVTNQERQEAHERFNLEELEKLERELEKKISEIDELQNQKAKITGELQNQDELNRSLKQEALQQKKSYKELEQEMETKNEILKQKTVELKRACQKQYELEQELAFYKIDAKFEPLGYFESEVKE----------DVPGESPYIGKARY 322 HSP 2 Score: 117.857 bits (294), Expect = 1.691e-25 Identity = 200/938 (21.32%), Postives = 423/938 (45.10%), Query Frame = 1
Query: 3427 QQQAMPPNNSP----LPGATYIPNGFL--------------PQIHNSHSTPILNTVPYSSI---VTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKR-----DELKTQSNSVSKQLHESKCELQSIKERLIMIEAQC-DERTS------EIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQ--NNVSKEDNKLEKILKNSSFELAQ----LKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRD--------------LAALRQN--------------HQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRI 6039
Q+ MPP S LP T P G + P P+ + Y T + AG L CNVP HH LE+ + KS K + + L+EDI +DL++ + + K+ E+ + + N+ +I +L E E +SL H ++ DEI ++ + +++ EL AD L ++ + +TT+ + K+ A+K+ + EELE++++E + +L KA +L ++Q L + E ++ +I S++++KD+EFQ + ++I L L +D+ + + +Q L E + LL + + L R+ +V Q+ + M+ +G++ + + I+ + ++++ + + A ++E ++K LE+L +K +L + + + ++K+ I ++E + L S++ KL + +H+ M++++ +L + ++ ++ ++E I + +E + L +R E+++ RQ + D + L +++ ++++L +K+ ++ ++LE L +Q +TL A E + + EK+ SE IKR D+L Q +S+ + E Q ++ +L +++ + D R ++R + + + E LQ I ++ + L + R++++ + L + I +K E++ L F Q V ++ + E+ LK S+ +L + L+ E+ + +LE +K++ L++ A + E+ LEE ++ + EQ R+ ++ LA + ++ LA+ R+N + E + +E + + + K++ +E+ A D RA L +L Q + ++ +LRN++
Sbjct: 1161 QRHFMPPAGSVIYTVLPDGTPAPQGTVVYGPPPPSSGRPVAPGTVIYGPPPVGTQIIYGPPPPHFTIPVIPAGVLHCNVPGHHNLENELTR------LEDIIDHLKSRRHKEKRSKERLQEDI----DDLEHQKEILRKEVEELRVSGQRRKRKNFVD----GHIGTLITELEL---------EKSLQH----HDEIEDEIGCIEKTLLKRRAELREADRLLAEAEAELQSTRAKTTDIIEKYTCAKKHLSTTESDAEELERRAQETARQLVKADQQLRMLQRSACDLEQHRAEQESMLTEINSVVSEKDSEFQALGKKIDTMTESLQKLHADIQVVAAKEANHLQALKEAESLLQEKKAVLERIDEQVYAQQQDIAGMDRLLGQKKEELHLLQDHIDHKKADLKEVLRDGELDVADCRQEIQEVKSLLEDLSAQKGELNAQVSEKKAQLGRLKQEILQEEDNLQTLASQINKLKSELKHVLEMVQLENNELQGLKLQHNQKVDEMENIQTTLLEGKLELENLQRTSQRLNGEVERQRQVLEKDHREMELLMTQMHTLQENVASLGSDKARVEESSQQLEKKL-------AQATKTLAATEENNRAASSNAEKLASE-----IKRLQKEIDQLHKQKHSLRQ---EGSVVQQQVQGKLNLLKDELNDTREGAWLAPQDLRNATRARDEMLREKTTLQAAIEESSARYKSLQDKEARKEQQLSHLQRAIEEK--EVRFL----FGPQVLKQVLRDLDIQEQQLKESTAKLKEHRQALEWELANRKTSLEMLNSKVNALEERALQLQQEEKWSAALEESLRSTRHQLEEKEQALREKASELAEMQKEAEISKADSGRVREQLASQRKNDEKRILLLKDAVKKQRAEYEQAMQEEKQEKNNLQKQLISVEQAAYDNHERAKRLMRELKQLQSEHTVLRNQV 2050
BLAST of centriolin vs. Ensembl Xenopus
Match: lrrc23 (leucine rich repeat containing 23 [Source:NCBI gene;Acc:549279]) HSP 1 Score: 70.0922 bits (170), Expect = 1.397e-11 Identity = 55/154 (35.71%), Postives = 85/154 (55.19%), Query Frame = 1
Query: 193 RIKKLNLDCGKGDKKIRYIEHLD--NLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILD 648
R++ LNL ++R +E L+ NL+++ L +R + + L+ L +LRELYL +N I RL+GLE L+NL L +R NQL S+ F+ + L +N NM ++E+ KL+ L L L + ENP YR+ ++ L L LD
Sbjct: 175 RLETLNLI----GNELRDLEGLECSNLSSLHTLELRSNQLLSTAGLN-LPSLRELYLGQNNISRLEGLEALVNLTTLHLRDNQLESL-DGFSEHLQALQYLNLRSNMVAKLQEVQKLYCLPRLRALVLRENPCEEEEGYRMETLIALPQLERLD 322
BLAST of centriolin vs. Ensembl Xenopus
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:448394]) HSP 1 Score: 66.2402 bits (160), Expect = 2.703e-10 Identity = 50/156 (32.05%), Postives = 85/156 (54.49%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
+++I + D L + L L G KI +++L+ L N+TVLS++ + + KIE L L NLRELYLS+N I ++GLEN L LD+ N++ I + + L + + N+ ++ ++ +L L + + NP+ A YR I++ L
Sbjct: 205 LRVIENLDSLRELDSLFL----GKNKITKLQNLETLTNLTVLSVQSNRLTKIEGLQNLVNLRELYLSDNGIQVIEGLENNNKLTTLDLASNRIKRIEN--IKHLSELQEFWMNDNLVENWSDLEELSGAPGLQTVYLERNPLQKDAQYRRKIMLAL 354 HSP 2 Score: 53.1434 bits (126), Expect = 3.344e-6 Identity = 61/210 (29.05%), Postives = 104/210 (49.52%), Query Frame = 1
Query: 157 FIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEEN----ELDRMSSRL--LETEKQLEEMKE 768
IK+I + + L + +L+L D +IR I +L+ L ++ +L + F+ + +IE L+ L +L+ LYL NKI R++ L L++L++ N+L I + + R L + +N I ++ L TL +L L V N + I + + +R Y L+D IE E N LD S+R+ +E K L E++E
Sbjct: 116 LIKLIENLEQLVTLTELDL----YDNQIRKIGNLETLRDLQILDLSFNLLRRIEGLESLSHLQRLYLVNNKISRIENFGTLTQLRLLELGSNRLRVIENLDSLR--ELDSLFLGKN---KITKLQNLETLTNLTVLSVQSNRLTKIEGLQNLVNLRELY---------LSDNGIQVIEGLENNNKLTTLDLASNRIKRIENIKHLSELQE 307
BLAST of centriolin vs. Ensembl Mouse
Match: Cntrl (centriolin [Source:MGI Symbol;Acc:MGI:1889576]) HSP 1 Score: 192.971 bits (489), Expect = 3.216e-51 Identity = 129/324 (39.81%), Postives = 202/324 (62.35%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L +K LNL K G KK RYIE+L+ + VL++ ++ I KIEK+DKL LREL LS NKI +++GLEN+ NL+ L++ GN++ IP WF ++ K L +N N S++++SKL L+DL L + +NPV A+ HY +I+ L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q K ++ QD+ K L ++ + ++LE +L +K LLK+K+ +L RACQK YELEQ++AF KIDAKF+ L+ + SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELESDLSTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYY---------PSEYAEIDKYPDESPYIGKSRY 393
BLAST of centriolin vs. Ensembl Mouse
Match: Cntrl (centriolin [Source:MGI Symbol;Acc:MGI:1889576]) HSP 1 Score: 193.741 bits (491), Expect = 1.175e-48 Identity = 130/327 (39.76%), Postives = 204/327 (62.39%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L +K LNL K G KK RYIE+L+ + VL++ ++ I KIEK+DKL LREL LS NKI +++GLEN+ NL+ L++ GN++ IP WF ++ K L +N N S++++SKL L+DL L + +NPV A+ HY +I+ L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q K ++ QD+ K L ++ QK + E+++ +L +K LLK+K+ +L RACQK YELEQ++AF KIDAKF+ L+ + SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELE---SDLSTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYP---------SEYAEIDKYPDESPYIGKSRY 393 HSP 2 Score: 130.954 bits (328), Expect = 1.338e-29 Identity = 208/939 (22.15%), Postives = 429/939 (45.69%), Query Frame = 1
Query: 3415 PQFVQQQAMPPNNSPLPG--ATYIPNGFLPQIHNSH--------------STPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKH-KSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNN-ISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQN-----EKKELESNLKILRKQESQVHE--TLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNK-------LEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKRVA---------------------KEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P ++ +P + SP+P A Y P+ LP ++SH PI+ P ++ + AG CN+PEHH LE+ ++ +H KS + +++ K+ ++ +D L DI +DL +Q K+ ++ + + ++D ++ + +L E E +SL H + DEI ++ + +++ EL AD L ++ +E+T + K DA++N + + E LEK+++E +L L KA +L ++Q + L K+ EE++ +I ++ KD +FQ +NE+ + +L SL+ D+ A +Q+L E + LL R EL LK++V Q+ L ++S++G R + + + +++ + ++E A ++K LE L +K +L I + + +++ ++K+E++ V+ +L + + +++ +L+++ +L + ++ ++V+LE+ + ++ +E + L +++ E+++ RQ + D +R++ + ++++ + LSKEK LQ EKK + + +ES E L LE V + R ELE++ +K + L ++ V +QL + + S++E L + D ++ + Q+ L E +LQ+ I + E + ++++ L EI + + E LQ +E+ K LE+ + EL KS + + L ++ A+ +L L+++ E++I LE ++ Q + EQ+ S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +L+Q +++Y+ L+ ++
Sbjct: 1244 PGYIMYTVLP-DGSPVPQGVALYAPSPPLP--NSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVP-LVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDI----DDL----LQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEI---------EKSLKH----HEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLA-------LHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEE-------ERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVA 2143
BLAST of centriolin vs. Ensembl Mouse
Match: Cntrl (centriolin [Source:MGI Symbol;Acc:MGI:1889576]) HSP 1 Score: 193.741 bits (491), Expect = 1.205e-48 Identity = 130/327 (39.76%), Postives = 204/327 (62.39%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L +K LNL K G KK RYIE+L+ + VL++ ++ I KIEK+DKL LREL LS NKI +++GLEN+ NL+ L++ GN++ IP WF ++ K L +N N S++++SKL L+DL L + +NPV A+ HY +I+ L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q K ++ QD+ K L ++ QK + E+++ +L +K LLK+K+ +L RACQK YELEQ++AF KIDAKF+ L+ + SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELE---SDLSTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYP---------SEYAEIDKYPDESPYIGKSRY 393 HSP 2 Score: 131.339 bits (329), Expect = 1.084e-29 Identity = 208/939 (22.15%), Postives = 429/939 (45.69%), Query Frame = 1
Query: 3415 PQFVQQQAMPPNNSPLPG--ATYIPNGFLPQIHNSH--------------STPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKH-KSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNN-ISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQN-----EKKELESNLKILRKQESQVHE--TLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNK-------LEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKRVA---------------------KEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P ++ +P + SP+P A Y P+ LP ++SH PI+ P ++ + AG CN+PEHH LE+ ++ +H KS + +++ K+ ++ +D L DI +DL +Q K+ ++ + + ++D ++ + +L E E +SL H + DEI ++ + +++ EL AD L ++ +E+T + K DA++N + + E LEK+++E +L L KA +L ++Q + L K+ EE++ +I ++ KD +FQ +NE+ + +L SL+ D+ A +Q+L E + LL R EL LK++V Q+ L ++S++G R + + + +++ + ++E A ++K LE L +K +L I + + +++ ++K+E++ V+ +L + + +++ +L+++ +L + ++ ++V+LE+ + ++ +E + L +++ E+++ RQ + D +R++ + ++++ + LSKEK LQ EKK + + +ES E L LE V + R ELE++ +K + L ++ V +QL + + S++E L + D ++ + Q+ L E +LQ+ I + E + ++++ L EI + + E LQ +E+ K LE+ + EL KS + + L ++ A+ +L L+++ E++I LE ++ Q + EQ+ S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +L+Q +++Y+ L+ ++
Sbjct: 1245 PGYIMYTVLP-DGSPVPQGVALYAPSPPLP--NSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVP-LVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDI----DDL----LQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEI---------EKSLKH----HEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLA-------LHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEE-------ERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVA 2144
BLAST of centriolin vs. Ensembl Mouse
Match: Cntrl (centriolin [Source:MGI Symbol;Acc:MGI:1889576]) HSP 1 Score: 193.741 bits (491), Expect = 1.205e-48 Identity = 130/327 (39.76%), Postives = 204/327 (62.39%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L +K LNL K G KK RYIE+L+ + VL++ ++ I KIEK+DKL LREL LS NKI +++GLEN+ NL+ L++ GN++ IP WF ++ K L +N N S++++SKL L+DL L + +NPV A+ HY +I+ L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q K ++ QD+ K L ++ QK + E+++ +L +K LLK+K+ +L RACQK YELEQ++AF KIDAKF+ L+ + SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELE---SDLSTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYP---------SEYAEIDKYPDESPYIGKSRY 393 HSP 2 Score: 131.339 bits (329), Expect = 1.084e-29 Identity = 208/939 (22.15%), Postives = 429/939 (45.69%), Query Frame = 1
Query: 3415 PQFVQQQAMPPNNSPLPG--ATYIPNGFLPQIHNSH--------------STPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKH-KSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNN-ISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQN-----EKKELESNLKILRKQESQVHE--TLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNK-------LEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKRVA---------------------KEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P ++ +P + SP+P A Y P+ LP ++SH PI+ P ++ + AG CN+PEHH LE+ ++ +H KS + +++ K+ ++ +D L DI +DL +Q K+ ++ + + ++D ++ + +L E E +SL H + DEI ++ + +++ EL AD L ++ +E+T + K DA++N + + E LEK+++E +L L KA +L ++Q + L K+ EE++ +I ++ KD +FQ +NE+ + +L SL+ D+ A +Q+L E + LL R EL LK++V Q+ L ++S++G R + + + +++ + ++E A ++K LE L +K +L I + + +++ ++K+E++ V+ +L + + +++ +L+++ +L + ++ ++V+LE+ + ++ +E + L +++ E+++ RQ + D +R++ + ++++ + LSKEK LQ EKK + + +ES E L LE V + R ELE++ +K + L ++ V +QL + + S++E L + D ++ + Q+ L E +LQ+ I + E + ++++ L EI + + E LQ +E+ K LE+ + EL KS + + L ++ A+ +L L+++ E++I LE ++ Q + EQ+ S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +L+Q +++Y+ L+ ++
Sbjct: 1245 PGYIMYTVLP-DGSPVPQGVALYAPSPPLP--NSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVP-LVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDI----DDL----LQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEI---------EKSLKH----HEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLA-------LHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEE-------ERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVA 2144
BLAST of centriolin vs. Ensembl Mouse
Match: Cntrl (centriolin [Source:MGI Symbol;Acc:MGI:1889576]) HSP 1 Score: 132.109 bits (331), Expect = 6.365e-30 Identity = 207/929 (22.28%), Postives = 425/929 (45.75%), Query Frame = 1
Query: 3445 PNNSPLPG--ATYIPNGFLPQIHNSH--------------STPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKH-KSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNN-ISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQN-----EKKELESNLKILRKQESQVHE--TLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNK-------LEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKRV---------------------AKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P+ SP+P A Y P+ LP ++SH PI+ P ++ + AG CN+PEHH LE+ ++ +H KS + +++ K+ ++ +D L DI +DL +Q K+ ++ + + ++D ++ + +L E E +SL H + DEI ++ + +++ EL AD L ++ +E+T + K DA++N + + E LEK+++E +L L KA +L ++Q + L K+ EE++ +I ++ KD +FQ +NE+ + +L SL+ D+ A +Q+L E + LL R EL LK++V Q+ L ++S++G R + + + +++ + ++E A ++K LE L +K +L I + + +++ ++K+E++ V+ +L + + +++ +L+++ +L + ++ ++V+LE+ + ++ +E + L +++ E+++ RQ + D +R++ + ++++ + LSKEK LQ EKK + + +ES E L LE V + R ELE++ +K + L ++ V +QL + + S++E L + D ++ + Q+ L E +LQ+ I + E + ++++ L EI + + E LQ +E+ K LE+ + EL KS + + L ++ A+ +L L+++ E++I LE ++ Q + EQ+ S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +L+Q +++Y+ L+ ++
Sbjct: 700 PDGSPVPQGVALYAPSPPLP--NSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVP-LVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDI----DDL----LQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEI---------EKSLKH----HEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLA-------LHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEE-------ERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVA 1590
BLAST of centriolin vs. UniProt/SwissProt
Match: sp|A2AL36|CNTRL_MOUSE (Centriolin OS=Mus musculus OX=10090 GN=Cntrl PE=1 SV=2) HSP 1 Score: 193.741 bits (491), Expect = 8.432e-48 Identity = 130/327 (39.76%), Postives = 204/327 (62.39%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L +K LNL K G KK RYIE+L+ + VL++ ++ I KIEK+DKL LREL LS NKI +++GLEN+ NL+ L++ GN++ IP WF ++ K L +N N S++++SKL L+DL L + +NPV A+ HY +I+ L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q K ++ QD+ K L ++ QK + E+++ +L +K LLK+K+ +L RACQK YELEQ++AF KIDAKF+ L+ + SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELE---SDLSTKKELLKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYP---------SEYAEIDKYPDESPYIGKSRY 393 HSP 2 Score: 131.339 bits (329), Expect = 7.586e-29 Identity = 208/939 (22.15%), Postives = 429/939 (45.69%), Query Frame = 1
Query: 3415 PQFVQQQAMPPNNSPLPG--ATYIPNGFLPQIHNSH--------------STPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKH-KSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNN-ISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQN-----EKKELESNLKILRKQESQVHE--TLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNK-------LEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKRVA---------------------KEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P ++ +P + SP+P A Y P+ LP ++SH PI+ P ++ + AG CN+PEHH LE+ ++ +H KS + +++ K+ ++ +D L DI +DL +Q K+ ++ + + ++D ++ + +L E E +SL H + DEI ++ + +++ EL AD L ++ +E+T + K DA++N + + E LEK+++E +L L KA +L ++Q + L K+ EE++ +I ++ KD +FQ +NE+ + +L SL+ D+ A +Q+L E + LL R EL LK++V Q+ L ++S++G R + + + +++ + ++E A ++K LE L +K +L I + + +++ ++K+E++ V+ +L + + +++ +L+++ +L + ++ ++V+LE+ + ++ +E + L +++ E+++ RQ + D +R++ + ++++ + LSKEK LQ EKK + + +ES E L LE V + R ELE++ +K + L ++ V +QL + + S++E L + D ++ + Q+ L E +LQ+ I + E + ++++ L EI + + E LQ +E+ K LE+ + EL KS + + L ++ A+ +L L+++ E++I LE ++ Q + EQ+ S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +L+Q +++Y+ L+ ++
Sbjct: 1245 PGYIMYTVLP-DGSPVPQGVALYAPSPPLP--NSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVP-LVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDI----DDL----LQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEI---------EKSLKH----HEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLA-------LHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEE-------ERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVA 2144
BLAST of centriolin vs. UniProt/SwissProt
Match: sp|Q7Z7A1|CNTRL_HUMAN (Centriolin OS=Homo sapiens OX=9606 GN=CNTRL PE=1 SV=2) HSP 1 Score: 187.578 bits (475), Expect = 5.983e-46 Identity = 123/327 (37.61%), Postives = 192/327 (58.72%), Query Frame = 1
Query: 133 GVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKK---QKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQA-YMGKGQF 1098
GVRYITE IK + +D+L IK LNL K G KK +YIE+L+ + VL++ ++ I KIEKLDKL LREL LS NKI +++G+EN+ NL+ L++ GN++ IP W ++ K L +N N S+++ISKL L+DL+ L + ENPV + HY + + L+ L L+ + V +++ A E+F E++R+ L + + EE+K Q + ++ QD+ K L ++ QK + E++K + RACQK YELEQ++AF KIDAKF+ L+ + P SE+++I D++ Y+GK ++
Sbjct: 79 GVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELT---RACQKQYELEQELAFYKIDAKFEPLNYY--P-------SEYAEIDKAPDESPYIGKSRY 393 HSP 2 Score: 105.145 bits (261), Expect = 6.790e-21 Identity = 211/941 (22.42%), Postives = 435/941 (46.23%), Query Frame = 1
Query: 3397 SAPSNNPQFVQQQAMPPNNSPLPGATYI---PNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLED---HFQNNGKHKSSWKLKQKF----KSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQ------DLLN-NISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSR---QVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNE----KKELESNLKILRKQE--SQVHET-LTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIF--DLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIF--ELEEIIKQQENNAHHYEQENRKLSNHLAVINR-------DLAALRQNHQFEMDNKDKELSRLRKR---------------------VAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIV 6042
P + +P N+ PL T + P P ++ P ++P+ + G L CNVPEHH LE+ ++ +H S K ++++ K SEK M E++H +DL E L ++++L+ T Q D ++ N+ SL E E +SL H + DEI ++ + +++ EL AD L ++ + +E+T + K DA+++ + + EELE++++E ++ L KA +L +Q + L K+ EE++ +I I+ KD++FQ ++++ + +L L+ D+ MA +Q+L E + LL R EL +LK++V Q+ + ++ +G + + + + +++ Q RL + +E+ RE L LE L +K +L I + + +K+ I+K+E++ V+ ++ K + ++I ML+++ +L + ++ R+ +LE+ ++ +E + L +++ EI+ +Q + D +R+ + +++ + LSKEK LQ + +K+L ++L E S++ ++ L LE V + + EL++++ +K S L +++ +QL E + + S++E L ++ + ++ + Q L E +LQ I F++ E + ++++ L EI + +++KL+++++ LQ E++KLE + QL+ E+T++ L+ +K+ L + ++ E++ + LE+ + Q + EQ+ + S L + + D + LR E +K+++ L++ + KE+ +E +A+D RA L +LNQ + +Y L+ ++
Sbjct: 1255 PVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGP--PPPNFSIPFIPM--------GVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEM-------EELHHNIDDL----------LQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEI---------EKSLKH----HEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSL---LEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLS-------LHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEI--EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV--LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMA 2141
BLAST of centriolin vs. UniProt/SwissProt
Match: sp|Q28CU0|LRC23_XENTR (Leucine-rich repeat-containing protein 23 OS=Xenopus tropicalis OX=8364 GN=lrrc23 PE=2 SV=1) HSP 1 Score: 71.2478 bits (173), Expect = 2.913e-11 Identity = 55/154 (35.71%), Postives = 85/154 (55.19%), Query Frame = 1
Query: 193 RIKKLNLDCGKGDKKIRYIEHLD--NLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILD 648
R++ LNL ++R +E L+ NL+++ L +R + + L+ L +LRELYL +N I RL+GLE L+NL L +R NQL S+ F+ + L +N NM ++E+ KL+ L L L + ENP YR+ ++ L L LD
Sbjct: 172 RLETLNLI----GNELRDLEGLECSNLSSLHTLELRSNQLLSTAGLN-LPSLRELYLGQNNISRLEGLEALVNLTTLHLRDNQLESL-DGFSEHLQALQYLNLRSNMVAKLQEVQKLYCLPRLRALVLRENPCEEEEGYRMETLIALPQLERLD 319
BLAST of centriolin vs. UniProt/SwissProt
Match: sp|Q32PL1|PP1R7_DANRE (Protein phosphatase 1 regulatory subunit 7 OS=Danio rerio OX=7955 GN=ppp1r7 PE=2 SV=1) HSP 1 Score: 67.781 bits (164), Expect = 3.498e-10 Identity = 56/177 (31.64%), Postives = 87/177 (49.15%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGK------------------GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I IA+ DHL ++ L L + G KI +++LD L+N+TVLSI+ + I K+E L L NLRELYLS N I ++GLEN L LD+ N++ I + +LT + + N ++ ++ +L K L + + NP+ YR I++ L
Sbjct: 161 IASIANLDHLTSLQMLELGSNRIRVIENLDSLSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLVNLRELYLSHNGIEVMEGLENNKKLSTLDIAANRIKKIEN-----ISHLTDLKEFWMNDNQIENWADLDELKNAKGLETVYLERNPLQKDPQYRRKIMLAL 332
BLAST of centriolin vs. UniProt/SwissProt
Match: sp|Q3UM45|PP1R7_MOUSE (Protein phosphatase 1 regulatory subunit 7 OS=Mus musculus OX=10090 GN=Ppp1r7 PE=1 SV=2) HSP 1 Score: 67.781 bits (164), Expect = 4.241e-10 Identity = 52/159 (32.70%), Postives = 87/159 (54.72%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I+ I + D L ++ L L G KI +++LD L N+TVLS++ + + KIE L L NLRELYLS N I ++GLEN L +LD+ N++ I + +LT++ + N+ +S ++ +L + L + + NP+ YR +++ L
Sbjct: 199 IRAIENIDTLTNLESLFL----GKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIEN-----ISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLAL 348
BLAST of centriolin vs. TrEMBL
Match: H6WA31 (Centriolin (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 696.812 bits (1797), Expect = 0.000e+0 Identity = 394/404 (97.52%), Postives = 396/404 (98.02%), Query Frame = 1
Query: 379 LDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQFITKKEVEMLMERKRMKQGHSKKEQEENNGRNSTQKLKEDFVDSLNEKVKEKLTELNQINKEISEKNKIVDNLNNNIDHKELFYDSNTPTKSLIPNFHRADRPRSALASFXXXXXXXXXXXXXXXXXETESINKHNEHSNTTDLFLEKVENLTEMQREAEELRRQ 1590
LD N + +ILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKDLLDLDVSENPVAAIAHYRLYIVMRLKYLLILDNREVL DEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQLEENLKSKDLLLKKKSEDLFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQFITKKEVEMLMERKRMKQGHSKKEQEENNGRNSTQKLKEDFVDSLNEKVKEKLTELNQINKEISEKNKI DNLNNNIDHKELFYDSNTPTKSLIPNFHRADRPRSALASFNRLSPLRTLLNRPRRLSETESINKHNEHSNTTDLFLEKVENLTEMQREAEELRRQ
Sbjct: 5 LDKKHNKTSFQILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKDLLDLDVSENPVAAIAHYRLYIVMRLKYLLILDNREVLVDEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQLEENLKSKDLLLKKKSEDLFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQFITKKEVEMLMERKRMKQGHSKKEQEENNGRNSTQKLKEDFVDSLNEKVKEKLTELNQINKEISEKNKIFDNLNNNIDHKELFYDSNTPTKSLIPNFHRADRPRSALASFNRLSPLRTLLNRPRRLSETESINKHNEHSNTTDLFLEKVENLTEMQREAEELRRQ 408
BLAST of centriolin vs. TrEMBL
Match: A0A1S3JJS6 (centriolin isoform X2 OS=Lingula unguis OX=7574 GN=LOC106173545 PE=4 SV=1) HSP 1 Score: 244.202 bits (622), Expect = 1.094e-60 Identity = 215/901 (23.86%), Postives = 455/901 (50.50%), Query Frame = 1
Query: 3472 TYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGS-------LFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDS-------LKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSL----------REETEFVTRETIASTSESLGH-MRARKSQLS---DEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQE-------NNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIVIFGRFLDKE 6069
Y+P G +H S + P K A LFCNVPEHH +ED+ + +LKQK K ++ ++ ++ L+ ++ R ++L+ +++ + +Q + + ++L ++ L + L RE E ++ +A + + R RKS+L+ DEI ++ + +++ EL AD L+ + + Q T+ ++D AR+ + + EE+E++S+EA ++L +A +++ +Q E +L K E + I +I+ KD EF+ ++E++ +L+ ++ +L +A E+ +E + L + + LL + R EL ++K+++ + L+ ++ +G R+ + + + R + N+L++E ++E + +E +L+ + L+ ++ L I + + + +KE+I + E+S +L S + K + +H+ M++M++ +LD+V ++ ++L +LER ++ + + + + +K E ++++QT+ E + L+ +KE +E SI+TL+KEK ++Q K + + L++ Q+ + + A + K + T+L+++ E T ++ L+ + ++ + K EL+ +KE L E + ++ ++++ +E++++QD IR + + +E + ++++ L E+ +K E + +++ + ++ + +E+ KL ++L N EL +K+E K + L+ + +L Q KK + TE+K ELE+ + Q E N E++ KL + L + R L Q E +L++ A+EI LE +A+D C RAN LS DLN+ R++Y+ + +++ LDKE
Sbjct: 1245 AYVPVGHPIAVHPSGPVQYVPVTPGPGQPPDGQKMAAVNLPGQEVLFCNVPEHHDMEDYIAQ--LQEKIKELKQKIKKLEKRETLSAEAERSAVKRLRAELEDRRDELEGLDLAMERQKASLRHMKEVEEKLKEEREGALKELEELKKTNAKTNRRREFLEGRSQYDVADSDYEYDYNPRQRKSRLNYLEDEIQCLEETLAKRRAELREADRLLQECQGDLQDARNQAKTTVQQYDQAREGLTTTVQQAEEIERRSKEAGVQLVQAQDQIEDLQKEIRQLDMEKAKKEATLQGILKVISTKDEEFRNLDEQVKDLEERLDQVEGELGLAEEREKETLASLKDCETLLENRRTELGKIKSQIDSERTQLENLDHQVGRRSTELQLVEESLARKQGELNKLMREAETEASNRHKEIQELRLTSQELQTQQRTLQADIADKQDQLQAIKEDIQQNEESLQILTSTVSKSRAELKHVVDMVKMEKSELDQVREQHGAKLKELERTQIALREEKEDLEYMQGETGKKQVECERLKQTLETQRETTESLKLEKELLEDSINTLAKEKDLIQESYKSYDDKVNQLKRAHLQLEDGILAGQRKQERLETQLKEIEKEVTEATADKEALERDLKTYTQHIKGKKSELKGLKENLNETEQKKEQMEKQLKETRMATDGALVELQRVQDSIRQSEQTQEECFKQQTQKQDLIRHLVTEVEEKEAEHQRMQQVLHRVKKELEREETKLSRLLSNGRLELENIKTEAAMKQDELDQNDKQLKQFKKQMEELQHTEEKFVELEQKVSQLETAVSEASNQRLSLERDQDKLLSELEEVKRHLHVTSQ-----------EYEQLQQNSAREIADLESVAQDHCRRANRLSQDLNELRQEYIEAKRKLMSQAEILDKE 2132 HSP 2 Score: 216.468 bits (550), Expect = 3.141e-52 Identity = 125/325 (38.46%), Postives = 221/325 (68.00%), Query Frame = 1
Query: 130 PGVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMS-EHSQISSTGDQAYMGKGQF 1098
PGVRYIT++ I+ + E HLD++ LNL K G KKI+YIE+LD L + VL++ + IEK+EKL+KL LREL LS N+I +++G+E L L++L++ GN + S+PHW ++ + L I ++N S+ E++KL +L+DL L V+ENPV + H LY++ L+ L +LD +++ +E++ A ++F+++E++ + +L +T+++LEE+++ K + ++++ ++ KK + E+IK++E +++KD LLK+K+ +L +ACQK+YELEQ++AF KIDAKF+ ++G + P N E S++ + + Y+G+ ++
Sbjct: 57 PGVRYITDDLIRRVTKEQHLDQVTVLNLTLSKEGGKKIKYIENLDGLRRLQVLNLSCNMIEKMEKLEKLTKLRELNLSFNRISKIEGIETLAALQVLNLTGNNIESLPHWLGKKLRSLRVIRLAKNKLQSLSELAKLKSLQDLSQLTVTENPVTELPHAHLYLIFHLRSLEVLDGQQLDIEEREEADQRFQQDEIENLERQLEDTQRRLEELQDEHNKSVHEIQEKEKQERSRKKKAGAAEEKIKEMEREIQTKDDLLKRKTAELTKACQKHYELEQELAFFKIDAKFE----NLGKIPTPGNGDVEESELGA--ESPYIGRARY 375
BLAST of centriolin vs. TrEMBL
Match: A0A1S3JIG3 (centriolin isoform X1 OS=Lingula unguis OX=7574 GN=LOC106173545 PE=4 SV=1) HSP 1 Score: 240.35 bits (612), Expect = 1.947e-59 Identity = 218/906 (24.06%), Postives = 460/906 (50.77%), Query Frame = 1
Query: 3472 TYIPNGFLPQIHNSHSTPILNTVPYSS-----------IVTSEMKNAGSLFCNVPEHHYLEDHF-QNNGKHKSSWKLKQKFKSDSEKYMMTLDS-------LKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSL----------REETEFVTRETIASTSESLGH-MRARKSQLS---DEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQE-------NNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIVIFGRFLDKE 6069
Y+P G +H S P+ VP + + + LFCNVPEHH +ED+ Q K K +LKQK K ++ ++ ++ L+ ++ R ++L+ +++ + +Q + + ++L ++ L + L RE E ++ +A + + R RKS+L+ DEI ++ + +++ EL AD L+ + + Q T+ ++D AR+ + + EE+E++S+EA ++L +A +++ +Q E +L K E + I +I+ KD EF+ ++E++ +L+ ++ +L +A E+ +E + L + + LL + R EL ++K+++ + L+ ++ +G R+ + + + R + N+L++E ++E + +E +L+ + L+ ++ L I + + + +KE+I + E+S +L S + K + +H+ M++M++ +LD+V ++ ++L +LER ++ + + + + +K E ++++QT+ E + L+ +KE +E SI+TL+KEK ++Q K + + L++ Q+ + + A + K + T+L+++ E T ++ L+ + ++ + K EL+ +KE L E + ++ ++++ +E++++QD IR + + +E + ++++ L E+ +K E + +++ + ++ + +E+ KL ++L N EL +K+E K + L+ + +L Q KK + TE+K ELE+ + Q E N E++ KL + L + R L Q E +L++ A+EI LE +A+D C RAN LS DLN+ R++Y+ + +++ LDKE
Sbjct: 1245 AYVPVGHPIAVHPS--GPV-QYVPVTPGPGQPPGDGQKMAAVNLPGQEVLFCNVPEHHDMEDYIAQLQEKIK---ELKQKIKKLEKRETLSAEAERSAVKRLRAELEDRRDELEGLDLAMERQKASLRHMKEVEEKLKEEREGALKELEELKKTNAKTNRRREFLEGRSQYDVADSDYEYDYNPRQRKSRLNYLEDEIQCLEETLAKRRAELREADRLLQECQGDLQDARNQAKTTVQQYDQAREGLTTTVQQAEEIERRSKEAGVQLVQAQDQIEDLQKEIRQLDMEKAKKEATLQGILKVISTKDEEFRNLDEQVKDLEERLDQVEGELGLAEEREKETLASLKDCETLLENRRTELGKIKSQIDSERTQLENLDHQVGRRSTELQLVEESLARKQGELNKLMREAETEASNRHKEIQELRLTSQELQTQQRTLQADIADKQDQLQAIKEDIQQNEESLQILTSTVSKSRAELKHVVDMVKMEKSELDQVREQHGAKLKELERTQIALREEKEDLEYMQGETGKKQVECERLKQTLETQRETTESLKLEKELLEDSINTLAKEKDLIQESYKSYDDKVNQLKRAHLQLEDGILAGQRKQERLETQLKEIEKEVTEATADKEALERDLKTYTQHIKGKKSELKGLKENLNETEQKKEQMEKQLKETRMATDGALVELQRVQDSIRQSEQTQEECFKQQTQKQDLIRHLVTEVEEKEAEHQRMQQVLHRVKKELEREETKLSRLLSNGRLELENIKTEAAMKQDELDQNDKQLKQFKKQMEELQHTEEKFVELEQKVSQLETAVSEASNQRLSLERDQDKLLSELEEVKRHLHVTSQ-----------EYEQLQQNSAREIADLESVAQDHCRRANRLSQDLNELRQEYIEAKRKLMSQAEILDKE 2133 HSP 2 Score: 216.468 bits (550), Expect = 2.913e-52 Identity = 125/325 (38.46%), Postives = 221/325 (68.00%), Query Frame = 1
Query: 130 PGVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMS-EHSQISSTGDQAYMGKGQF 1098
PGVRYIT++ I+ + E HLD++ LNL K G KKI+YIE+LD L + VL++ + IEK+EKL+KL LREL LS N+I +++G+E L L++L++ GN + S+PHW ++ + L I ++N S+ E++KL +L+DL L V+ENPV + H LY++ L+ L +LD +++ +E++ A ++F+++E++ + +L +T+++LEE+++ K + ++++ ++ KK + E+IK++E +++KD LLK+K+ +L +ACQK+YELEQ++AF KIDAKF+ ++G + P N E S++ + + Y+G+ ++
Sbjct: 57 PGVRYITDDLIRRVTKEQHLDQVTVLNLTLSKEGGKKIKYIENLDGLRRLQVLNLSCNMIEKMEKLEKLTKLRELNLSFNRISKIEGIETLAALQVLNLTGNNIESLPHWLGKKLRSLRVIRLAKNKLQSLSELAKLKSLQDLSQLTVTENPVTELPHAHLYLIFHLRSLEVLDGQQLDIEEREEADQRFQQDEIENLERQLEDTQRRLEELQDEHNKSVHEIQEKEKQERSRKKKAGAAEEKIKEMEREIQTKDDLLKRKTAELTKACQKHYELEQELAFFKIDAKFE----NLGKIPTPGNGDVEESELGA--ESPYIGRARY 375
BLAST of centriolin vs. TrEMBL
Match: A0A1S3JIC2 (centriolin isoform X3 OS=Lingula unguis OX=7574 GN=LOC106173545 PE=4 SV=1) HSP 1 Score: 240.35 bits (612), Expect = 1.957e-59 Identity = 218/906 (24.06%), Postives = 460/906 (50.77%), Query Frame = 1
Query: 3472 TYIPNGFLPQIHNSHSTPILNTVPYSS-----------IVTSEMKNAGSLFCNVPEHHYLEDHF-QNNGKHKSSWKLKQKFKSDSEKYMMTLDS-------LKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSL----------REETEFVTRETIASTSESLGH-MRARKSQLS---DEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQE-------NNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIVIFGRFLDKE 6069
Y+P G +H S P+ VP + + + LFCNVPEHH +ED+ Q K K +LKQK K ++ ++ ++ L+ ++ R ++L+ +++ + +Q + + ++L ++ L + L RE E ++ +A + + R RKS+L+ DEI ++ + +++ EL AD L+ + + Q T+ ++D AR+ + + EE+E++S+EA ++L +A +++ +Q E +L K E + I +I+ KD EF+ ++E++ +L+ ++ +L +A E+ +E + L + + LL + R EL ++K+++ + L+ ++ +G R+ + + + R + N+L++E ++E + +E +L+ + L+ ++ L I + + + +KE+I + E+S +L S + K + +H+ M++M++ +LD+V ++ ++L +LER ++ + + + + +K E ++++QT+ E + L+ +KE +E SI+TL+KEK ++Q K + + L++ Q+ + + A + K + T+L+++ E T ++ L+ + ++ + K EL+ +KE L E + ++ ++++ +E++++QD IR + + +E + ++++ L E+ +K E + +++ + ++ + +E+ KL ++L N EL +K+E K + L+ + +L Q KK + TE+K ELE+ + Q E N E++ KL + L + R L Q E +L++ A+EI LE +A+D C RAN LS DLN+ R++Y+ + +++ LDKE
Sbjct: 1245 AYVPVGHPIAVHPS--GPV-QYVPVTPGPGQPPGDGQKMAAVNLPGQEVLFCNVPEHHDMEDYIAQLQEKIK---ELKQKIKKLEKRETLSAEAERSAVKRLRAELEDRRDELEGLDLAMERQKASLRHMKEVEEKLKEEREGALKELEELKKTNAKTNRRREFLEGRSQYDVADSDYEYDYNPRQRKSRLNYLEDEIQCLEETLAKRRAELREADRLLQECQGDLQDARNQAKTTVQQYDQAREGLTTTVQQAEEIERRSKEAGVQLVQAQDQIEDLQKEIRQLDMEKAKKEATLQGILKVISTKDEEFRNLDEQVKDLEERLDQVEGELGLAEEREKETLASLKDCETLLENRRTELGKIKSQIDSERTQLENLDHQVGRRSTELQLVEESLARKQGELNKLMREAETEASNRHKEIQELRLTSQELQTQQRTLQADIADKQDQLQAIKEDIQQNEESLQILTSTVSKSRAELKHVVDMVKMEKSELDQVREQHGAKLKELERTQIALREEKEDLEYMQGETGKKQVECERLKQTLETQRETTESLKLEKELLEDSINTLAKEKDLIQESYKSYDDKVNQLKRAHLQLEDGILAGQRKQERLETQLKEIEKEVTEATADKEALERDLKTYTQHIKGKKSELKGLKENLNETEQKKEQMEKQLKETRMATDGALVELQRVQDSIRQSEQTQEECFKQQTQKQDLIRHLVTEVEEKEAEHQRMQQVLHRVKKELEREETKLSRLLSNGRLELENIKTEAAMKQDELDQNDKQLKQFKKQMEELQHTEEKFVELEQKVSQLETAVSEASNQRLSLERDQDKLLSELEEVKRHLHVTSQ-----------EYEQLQQNSAREIADLESVAQDHCRRANRLSQDLNELRQEYIEAKRKLMSQAEILDKE 2133 HSP 2 Score: 216.468 bits (550), Expect = 2.978e-52 Identity = 125/325 (38.46%), Postives = 221/325 (68.00%), Query Frame = 1
Query: 130 PGVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMS-EHSQISSTGDQAYMGKGQF 1098
PGVRYIT++ I+ + E HLD++ LNL K G KKI+YIE+LD L + VL++ + IEK+EKL+KL LREL LS N+I +++G+E L L++L++ GN + S+PHW ++ + L I ++N S+ E++KL +L+DL L V+ENPV + H LY++ L+ L +LD +++ +E++ A ++F+++E++ + +L +T+++LEE+++ K + ++++ ++ KK + E+IK++E +++KD LLK+K+ +L +ACQK+YELEQ++AF KIDAKF+ ++G + P N E S++ + + Y+G+ ++
Sbjct: 57 PGVRYITDDLIRRVTKEQHLDQVTVLNLTLSKEGGKKIKYIENLDGLRRLQVLNLSCNMIEKMEKLEKLTKLRELNLSFNRISKIEGIETLAALQVLNLTGNNIESLPHWLGKKLRSLRVIRLAKNKLQSLSELAKLKSLQDLSQLTVTENPVTELPHAHLYLIFHLRSLEVLDGQQLDIEEREEADQRFQQDEIENLERQLEDTQRRLEELQDEHNKSVHEIQEKEKQERSRKKKAGAAEEKIKEMEREIQTKDDLLKRKTAELTKACQKHYELEQELAFFKIDAKFE----NLGKIPTPGNGDVEESELGA--ESPYIGRARY 375
BLAST of centriolin vs. TrEMBL
Match: A0A1S3JJ59 (centriolin isoform X4 OS=Lingula unguis OX=7574 GN=LOC106173545 PE=4 SV=1) HSP 1 Score: 238.424 bits (607), Expect = 7.336e-59 Identity = 216/899 (24.03%), Postives = 456/899 (50.72%), Query Frame = 1
Query: 3472 TYIPNGFLPQIHNSHSTPILNTVPYSS-----------IVTSEMKNAGSLFCNVPEHHYLEDHF-QNNGKHKSSWKLKQKFKSDSEKYMMTLDS-------LKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSL----------REETEFVTRETIASTSESLGH-MRARKSQLS---DEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIVIFGRFLDKE 6069
Y+P G +H S P+ VP + + + LFCNVPEHH +ED+ Q K K +LKQK K ++ ++ ++ L+ ++ R ++L+ +++ + +Q + + ++L ++ L + L RE E ++ +A + + R RKS+L+ DEI ++ + +++ EL AD L+ + + Q T+ ++D AR+ + + EE+E++S+EA ++L +A +++ +Q E +L K E + I +I+ KD EF+ ++E++ +L+ ++ +L +A E+ +E + L + + LL + R EL ++K+++ + L+ ++ +G R+ + + + R + N+L++E ++E + +E +L+ + L+ ++ L I + + + +KE+I + E+S +L S + K + +H+ M++M++ +LD+V ++ ++L +LER ++ + + + + +K E ++++QT+ E + L+ +KE +E SI+TL+KEK ++Q K + + L++ Q+ + + A + K + T+L+++ E T ++ L+ + ++ + K EL+ +KE L E + ++ ++++ +E++++QD IR + + +E + ++++ L E+ +K E + +++ + ++ + +E+ KL ++L N EL +K+E K + L+ + +L Q KK + TE+K ELE+ + Q E E N++LS + R+ L+QN A+EI LE +A+D C RAN LS DLN+ R++Y+ + +++ LDKE
Sbjct: 1245 AYVPVGHPIAVHPS--GPV-QYVPVTPGPGQPPGDGQKMAAVNLPGQEVLFCNVPEHHDMEDYIAQLQEKIK---ELKQKIKKLEKRETLSAEAERSAVKRLRAELEDRRDELEGLDLAMERQKASLRHMKEVEEKLKEEREGALKELEELKKTNAKTNRRREFLEGRSQYDVADSDYEYDYNPRQRKSRLNYLEDEIQCLEETLAKRRAELREADRLLQECQGDLQDARNQAKTTVQQYDQAREGLTTTVQQAEEIERRSKEAGVQLVQAQDQIEDLQKEIRQLDMEKAKKEATLQGILKVISTKDEEFRNLDEQVKDLEERLDQVEGELGLAEEREKETLASLKDCETLLENRRTELGKIKSQIDSERTQLENLDHQVGRRSTELQLVEESLARKQGELNKLMREAETEASNRHKEIQELRLTSQELQTQQRTLQADIADKQDQLQAIKEDIQQNEESLQILTSTVSKSRAELKHVVDMVKMEKSELDQVREQHGAKLKELERTQIALREEKEDLEYMQGETGKKQVECERLKQTLETQRETTESLKLEKELLEDSINTLAKEKDLIQESYKSYDDKVNQLKRAHLQLEDGILAGQRKQERLETQLKEIEKEVTEATADKEALERDLKTYTQHIKGKKSELKGLKENLNETEQKKEQMEKQLKETRMATDGALVELQRVQDSIRQSEQTQEECFKQQTQKQDLIRHLVTEVEEKEAEHQRMQQVLHRVKKELEREETKLSRLLSNGRLELENIKTEAAMKQDELDQNDKQLKQFKKQMEELQHTEEKFVELEQKVSQLETAVS--EASNQRLS-----LEREYEQLQQNS------------------AREIADLESVAQDHCRRANRLSQDLNELRQEYIEAKRKLMSQAEILDKE 2112 HSP 2 Score: 216.468 bits (550), Expect = 3.096e-52 Identity = 125/325 (38.46%), Postives = 221/325 (68.00%), Query Frame = 1
Query: 130 PGVRYITEEFIKIIAHEDHLDRIKKLNLDCGK-GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMS-EHSQISSTGDQAYMGKGQF 1098
PGVRYIT++ I+ + E HLD++ LNL K G KKI+YIE+LD L + VL++ + IEK+EKL+KL LREL LS N+I +++G+E L L++L++ GN + S+PHW ++ + L I ++N S+ E++KL +L+DL L V+ENPV + H LY++ L+ L +LD +++ +E++ A ++F+++E++ + +L +T+++LEE+++ K + ++++ ++ KK + E+IK++E +++KD LLK+K+ +L +ACQK+YELEQ++AF KIDAKF+ ++G + P N E S++ + + Y+G+ ++
Sbjct: 57 PGVRYITDDLIRRVTKEQHLDQVTVLNLTLSKEGGKKIKYIENLDGLRRLQVLNLSCNMIEKMEKLEKLTKLRELNLSFNRISKIEGIETLAALQVLNLTGNNIESLPHWLGKKLRSLRVIRLAKNKLQSLSELAKLKSLQDLSQLTVTENPVTELPHAHLYLIFHLRSLEVLDGQQLDIEEREEADQRFQQDEIENLERQLEDTQRRLEELQDEHNKSVHEIQEKEKQERSRKKKAGAAEEKIKEMEREIQTKDDLLKRKTAELTKACQKHYELEQELAFFKIDAKFE----NLGKIPTPGNGDVEESELGA--ESPYIGRARY 375
BLAST of centriolin vs. Ensembl Cavefish
Match: drc3 (dynein regulatory complex subunit 3 [Source:ZFIN;Acc:ZDB-GENE-061103-349]) HSP 1 Score: 72.0182 bits (175), Expect = 3.586e-12 Identity = 61/189 (32.28%), Postives = 106/189 (56.08%), Query Frame = 1
Query: 232 KKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMK--ENQLKLQKD 792
KKI I+HL ++T L + ++IEKI+ L+KL NL L LS NKI ++GLE L+ L+ L + NQ+ +I T ++L ++ N+ I+ + L K+L L+++ NP+ +Y++++V L L+ LD R V ++ A+ E++ M+ L+ ++ +E K E +L+L KD
Sbjct: 53 KKILQIDHLWEFTSLTKLQLNNNSIEKIQGLEKLTNLLWLDLSFNKIKMIEGLEALVKLQTLSLSNNQIPAIEKMDT--LEHLEILSLGENVISQIDNVIYLRRFKNLRSLNLARNPICQETNYKIFVVAYLPDLVYLDFRLVDEQTRERAL-----TEINVMTDNELKEKRAMEAQKITEQELQLHKD 234
BLAST of centriolin vs. Ensembl Cavefish
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:111191999]) HSP 1 Score: 68.1662 bits (165), Expect = 3.191e-11 Identity = 54/159 (33.96%), Postives = 85/159 (53.46%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I+II + D L + L L G KI +++LD L+N+TVLSI+ + I K+E L + NLRELYLS N I ++GLEN L LD+ N++ I + +LT + + N ++ ++ +L K L + + NP+ YR I++ L
Sbjct: 184 IRIIENLDALTSLDSLFL----GTNKITKLQNLDGLHNLTVLSIQSNRITKLEGLQNMVNLRELYLSHNGIEVIEGLENNKKLTTLDIAANRIKKIEN-----ISHLTDLQEFWMNDNQIENWSDLDELKNAKGLETVYLERNPLQKDPQYRRKIMLAL 333 HSP 2 Score: 58.151 bits (139), Expect = 4.913e-8 Identity = 45/130 (34.62%), Postives = 70/130 (53.85%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLK 549
I IA+ +HL + L L G +IR IE+LD L ++ L + + I K++ LD L NL L + N+I +L+GL+N++NL+ L + N + I K LT ++ + N IE IS L L+
Sbjct: 162 ISSIANLEHLTSLHMLEL----GSNRIRIIENLDALTSLDSLFLGTNKITKLQNLDGLHNLTVLSIQSNRITKLEGLQNMVNLRELYLSHNGIEVIEGL--ENNKKLTTLDIAANRIKKIENISHLTDLQ 285
BLAST of centriolin vs. Ensembl Cavefish
Match: drc3 (dynein regulatory complex subunit 3 [Source:ZFIN;Acc:ZDB-GENE-061103-349]) HSP 1 Score: 66.2402 bits (160), Expect = 2.669e-10 Identity = 62/186 (33.33%), Postives = 101/186 (54.30%), Query Frame = 1
Query: 235 KIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKD 792
KI I+HL ++T L + ++IEKI+ L+KL NL L LS NKI ++GLE L+ L+ L + NQ+ +I T ++L ++ N+ I+ + L K+L L+++ NP+ +Y++++V L L+ LD R L DE+ NEL R +E +K + E +L+L KD
Sbjct: 42 KILQIDHLWEFTSLTKLQLNNNSIEKIQGLEKLTNLLWL-LSFNKIKMIEGLEALVKLQTLSLSNNQIPAIEKMDT--LEHLEILSLGENVISQIDNVIYLRRFKNLRSLNLARNPICQETNYKIFVVAYLPDLVYLDFR--LVDEQT--------NELK--EKRAMEAQK----ITEQELQLHKD 208
BLAST of centriolin vs. Ensembl Cavefish
Match: lrrc23 (leucine rich repeat containing 23 [Source:NCBI gene;Acc:103047179]) HSP 1 Score: 58.9214 bits (141), Expect = 2.436e-8 Identity = 45/138 (32.61%), Postives = 75/138 (54.35%), Query Frame = 1
Query: 196 IKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXV-SENPVAAIAHYR 606
++ LNL G G +++ +E+ L N+ L +R +++E + + L NLR LYL++NKI +L+GLE L L L +RGNQL ++ + K L +N N+ S + + L + L V + NP + + YR
Sbjct: 152 LESLNL-TGNGIQRVSGLEY-HRLTNLVTLELRGNSLETTDGI-YLPNLRNLYLAQNKIKQLEGLEKLERLTTLHLRGNQLETL-DGLSPSMKSLQYLNIRDNLIASRKALQSLLGVAQTLQAIVLTGNPFSDMEDYR 285
BLAST of centriolin vs. Ensembl Cavefish
Match: lrguk (leucine rich repeats and guanylate kinase domain containing [Source:NCBI gene;Acc:103023555]) HSP 1 Score: 55.0694 bits (131), Expect = 1.035e-6 Identity = 49/169 (28.99%), Postives = 82/169 (48.52%), Query Frame = 1
Query: 283 LSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRC--------------------KYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSR 729
L + +++I +I+ ++K +L ++ NKI R+ GL NL LK L +RGN + I + T R L INF NM I+E+S L + L +L++ NPV YR+ ++ L L LD V A +K A+ +++ L+ +++R
Sbjct: 118 LILDYNSITEIKGVEKCSSLIHFSIAHNKISRISGLNNL-PLKHLCLRGNLIKKIENLHTLRALQFLDISSNRIHSLSGLQNLPLLGSINFESNMISEIKEVSYLHDILLLRELNLKRNPVQEQPDYRMMVIFLLNRLTELDELAVTAVDKVTAVNKYDP-PLEVVAAR 284
BLAST of centriolin vs. Ensembl Sea Lamprey
Match: ppp1r7 (protein phosphatase 1, regulatory (inhibitor) subunit 7 [Source:NCBI gene;Acc:560323]) HSP 1 Score: 64.3142 bits (155), Expect = 9.784e-11 Identity = 47/140 (33.57%), Postives = 77/140 (55.00%), Query Frame = 1
Query: 226 GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYL 636
G KI +++LD+L N+TVLSI+ + I KIE L L NL+ELYLS N I ++GLEN L LD+ N++ I + +LT++ + N + ++ +L + L + + NP+ YR I++ L ++
Sbjct: 196 GKNKITKLQNLDSLTNLTVLSIQSNRITKIEGLSSLVNLQELYLSHNGIEVIEGLENNKKLTTLDIAANRVRRIEN-----VGHLTELQEFWMNDNQISNWNDVDELKNARGLQTVYLERNPLQRDPQYRRKIMLALPWV 330 HSP 2 Score: 53.1434 bits (126), Expect = 4.088e-7 Identity = 29/73 (39.73%), Postives = 48/73 (65.75%), Query Frame = 1
Query: 229 DKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSI 447
D ++ IE+LD L N+ +L I F+ + KIE LD L +R+L+L NKI +++ L +L L++L+V N++ I
Sbjct: 109 DNVLKKIENLDTLVNLEMLDISFNVLRKIEGLDTLRKVRKLFLVSNKITKIENLNSLTELRMLEVASNRIRVI 181
BLAST of centriolin vs. Ensembl Sea Lamprey
Match: LRRC49 (leucine rich repeat containing 49 [Source:HGNC Symbol;Acc:HGNC:25965]) HSP 1 Score: 53.1434 bits (126), Expect = 6.946e-7 Identity = 53/198 (26.77%), Postives = 92/198 (46.46%), Query Frame = 1
Query: 157 FIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLK----------------------XXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIA 684
I+ H HL R+ L+L ++ I L NL ++ VL + + I KI L+ L L L L N+I+R++ L +L L++L++ GNQ+ + R L ++N RN S++E+ L +L+ L ++ + NP+A A YR + + L LD + V +E+++A
Sbjct: 63 LIRRAQHLSHLRRLVFLDLYA----NELEEISGLYNLRSLRVLMLGKNRIRKITSLESLTKLDVLDLHGNQIVRIENLSHLSELRVLNLAGNQITHVDS--LRGLHSLAELNLRRNNISSMKEVDCLPSLQRLFLSYNNIANFDGIVCLREAPSLCEVALDGNPLAQEACYRQTALRHMGQLRQLDMKRVTEEERRLA 254
BLAST of centriolin vs. Ensembl Sea Lamprey
Match: cep97 (centrosomal protein 97 [Source:ZFIN;Acc:ZDB-GENE-031030-11]) HSP 1 Score: 52.373 bits (124), Expect = 1.371e-6 Identity = 48/168 (28.57%), Postives = 78/168 (46.43%), Query Frame = 1
Query: 187 LDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPV------AAIAHYRLYIVMRLKYLLILDNREVLADE 672
L +K+LNL I IE L +L ++ L++ ++I+ IE L+ +L + LS+N I L + L NL+ L + GN + S+ T L ++ + N + E+S L L+ L L V +NP A +R Y++ L +LD V E
Sbjct: 78 LSSLKQLNLP----RNSIPAIEGLKDLCHLQWLNLAGNSIKTIEHLNGCTSLTYVDLSDNNISHLGDMSKLSNLRTLLLHGNMVTSLRTAPTHLPPQLGILSLAENEITDLTEMSHLSCLRSLEQLSVMKNPCMLSAPSAPACDHRPYVLSWCLTLRVLDGHVVTQKE 241
BLAST of centriolin vs. Ensembl Sea Lamprey
Match: lrrc6 (leucine rich repeat containing 6 [Source:NCBI gene;Acc:432388]) HSP 1 Score: 50.8322 bits (120), Expect = 2.739e-6 Identity = 50/177 (28.25%), Postives = 83/177 (46.89%), Query Frame = 1
Query: 283 LSIRFHAIEKIEKLDKLC-NLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQ 810
LS+ IE+++ LD C +L+ LYL N I R++ L L L+ +++ N + I + + C+ L K++ + N + + L L +L + NP A YR Y+V L L LD +E+ E+ A EL+ R+LE E + + Q A+Q+Q
Sbjct: 23 LSLHQQQIERLQHLDVWCRHLKTLYLHNNVIPRIENLSRLKELEYINLALNNVERIEN--LQGCESLQKLDLTVNFVGELSSVETLRHNPLLEELFLVGNPCADFEGYRPYVVATLPQLKRLDGQEIERSERIRA-----HQELEWTRRRVLEQEAEYLARRAQQKLSYAGVARQNQ 192
BLAST of centriolin vs. Ensembl Sea Lamprey
Match: LRRC9 (leucine rich repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:19848]) HSP 1 Score: 50.0618 bits (118), Expect = 6.246e-6 Identity = 57/229 (24.89%), Postives = 101/229 (44.10%), Query Frame = 1
Query: 115 ILMNPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHW--FTRRCKY---LTKINFSRNMFDSI-EEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKL 783
+L PP VR R K ++LD + + + +LN+ITVL++ +++ +++ +++L LR L +S N++ RLD L ++ +L+ LDV NQL ++ +R C +++ +R+ S+ L TL NP + RL V +L+ L LD + +E A+ Q + +S LL E + L L
Sbjct: 122 VLSMPPTVR----------------PRPKLISLD----EASLLSLTKTSSLNHITVLNLHGNSLTRLKDINRLVFLRRLVVSFNELARLDDLTHMPSLEYLDVSHNQLGTLEGMKDLSRLCHLDISWNRLSCARDAAGSLRRHAGALVTLD------TRHNPWLKLECARLRFVGQLRSLASLDGVPITEEEVAAALRQAASSH---ISQALLLAHACTEAARPRCLSL 321
BLAST of centriolin vs. Ensembl Nematostella
Match: EDO29833 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2I2]) HSP 1 Score: 115.161 bits (287), Expect = 1.511e-29 Identity = 61/131 (46.56%), Postives = 90/131 (68.70%), Query Frame = 1
Query: 130 PGVRYITEEFIKIIAHEDHLDRIKKLNLDCGKG-DKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSI 519
GV YI+E IK ++ E++L IK LNL GK +KK RY+E+LDNL N++ L I H IEKIEKLDKL LREL LS N I +L+GLE+L++L++L++ NQ+ ++P ++ + L +F+ N +S+
Sbjct: 14 AGVAYISENLIKRLSKEENLANIKSLNLALGKDLNKKFRYLENLDNLKNLSALHISNHMIEKIEKLDKLTQLRELNLSRNSITKLEGLESLVHLQVLNISRNQIQTLPAPLMKKLRELRVFHFAYNSLESV 144
BLAST of centriolin vs. Ensembl Nematostella
Match: EDO33841 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR20]) HSP 1 Score: 72.4034 bits (176), Expect = 1.387e-12 Identity = 63/197 (31.98%), Postives = 114/197 (57.87%), Query Frame = 1
Query: 523 EISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAK-----QDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQF 1098
EI+KL L+DL ++ + NP++ +AH LY + +L+ L LD + V+ DE+ A ++F ++E+ R+ + L K + + E + + + K Q Q +KD Q++ K+L+ L +K+ +L K+++L RAC+K + LEQ++AF K+DAKF+ H+G L P+ +E ++ + AY+GK +
Sbjct: 113 EITKLRPLQDLTEISMVGNPMSTLAHSHLYAIFQLRSLTTLDKQTVMDDERVAADDRFGQDEIRRLEAELNRQNKLYDALFEEKHSVSTELDKVSRLHQQQKEKDTQLAQRN-----KELQRELNAKEEILASKTKELSRACEKQFRLEQELAFYKLDAKFE----HLGKLPWPEG-AEFPEVED-DEAAYIGKAGY 298
BLAST of centriolin vs. Ensembl Nematostella
Match: EDO49856 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REV6]) HSP 1 Score: 63.5438 bits (153), Expect = 3.379e-10 Identity = 49/155 (31.61%), Postives = 88/155 (56.77%), Query Frame = 1
Query: 265 LNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSR 729
L+ + +L +R + + ++ L NLRELYL+ N I +++GL+ L +L L +R NQ++S+ F+ K L +N N S +E+ KL L L L + ENPV+ YR+ +++ L+ L LD E DE++ A E + + + + ++++
Sbjct: 164 LSRLAILELRGNKLMTTTGMN-LENLRELYLAANTIRKVEGLDRLEHLTKLHLRDNQIDSL-EGFSENMKNLQYLNLRGNSISSNKEVQKLKCLPLLRALVLMENPVSDEDDYRIEVLIALRRLERLDKDEYTEDERQEAEEIYNQRQEEELAAQ 316
BLAST of centriolin vs. Ensembl Nematostella
Match: EDO48550 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJB1]) HSP 1 Score: 56.6102 bits (135), Expect = 9.539e-8 Identity = 40/139 (28.78%), Postives = 74/139 (53.24%), Query Frame = 1
Query: 283 LSIRFHAIEKIEKLDKLC-NLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQF 696
+S+ IE++E LDKLC +L+ LYL N I +++ + L L+ +++ N + I + C+ L K++ + N D + I L L ++ ++ NP YR Y++ L L LD +EV E+ +A++++
Sbjct: 23 ISLHQQEIERLELLDKLCRDLKILYLQSNLIPKIENVSRLKKLEYINLALNNITRIENL--EGCESLKKLDLTVNFVDELTSIKSLKCNIHLQEMFLTGNPCTDYDGYREYVIATLTQLKWLDGKEVEKSERILALQEY 159
BLAST of centriolin vs. Ensembl Nematostella
Match: EDO44937 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU20]) HSP 1 Score: 55.4546 bits (132), Expect = 1.126e-7 Identity = 37/110 (33.64%), Postives = 65/110 (59.09%), Query Frame = 1
Query: 229 DKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLK 549
D +I IE+LD L N+ +L + F+ I+ IE L+ L L +LYL +NKI R++GLE+L L ++++ N++ + ++LTK+ +N ++ +S L +LK
Sbjct: 80 DNQISKIENLDRLVNLRILDLSFNVIKVIENLNSLTKLEKLYLVQNKIGRIEGLEHLTELTMVELGANKIRVLEGL-----EHLTKLESLFVGKNKITELQNLSGLCSLK 184 HSP 2 Score: 50.447 bits (119), Expect = 4.247e-6 Identity = 44/159 (27.67%), Postives = 83/159 (52.20%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYL 636
I+++ +HL +++ L + G KI +++L L ++ VLSI+ + I +++ L+ L +L ELY+S N I + GLE+L L LD+ N++ I + L + F+ N + E++ +L L + + NP++ YR + + L L
Sbjct: 149 IRVLEGLEHLTKLESLFV----GKNKITELQNLSGLCSLKVLSIQSNRIVELKGLEHLDSLEELYISHNGIEEIKGLESLTKLNTLDLASNRIKRISN--VGHLLNLEEFWFNDNQLEHWEDLDELAKCPKLHTVYLERNPLSRDTAYRRKVKLALPAL 301
BLAST of centriolin vs. Ensembl Medaka
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:101158055]) HSP 1 Score: 66.6254 bits (161), Expect = 8.434e-11 Identity = 53/159 (33.33%), Postives = 86/159 (54.09%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I++I + D L + L L G KI +++LD L+N++VLSI+ + I KIE L L NL+ELYLS N I ++GLEN L LD+ N++ I + +LT++ + N ++ ++ +L K L + + NP+ YR I++ L
Sbjct: 184 IRVIENLDGLTSLTSLFL----GTNKINKLQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEGLENNKKLTTLDIAANRVKKIEN-----ISHLTELQEFWMNDNQIENWSDLDELKNAKSLETVYLERNPLQKDPQYRRKIMLAL 333 HSP 2 Score: 60.4622 bits (145), Expect = 8.975e-9 Identity = 46/136 (33.82%), Postives = 73/136 (53.68%), Query Frame = 1
Query: 142 YITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLK 549
++ I IA+ +H ++ L L G +IR IE+LD L ++T L + + I K++ LD L NL L + N+I +++GL+NL+NLK L + N + I K LT ++ + N IE IS L L+
Sbjct: 156 FLVHNKITGIANLEHFSFLEMLEL----GSNRIRVIENLDGLTSLTSLFLGTNKINKLQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEGL--ENNKKLTTLDIAANRVKKIENISHLTELQ 285
BLAST of centriolin vs. Ensembl Medaka
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:101158055]) HSP 1 Score: 63.1586 bits (152), Expect = 1.465e-9 Identity = 53/159 (33.33%), Postives = 86/159 (54.09%), Query Frame = 1
Query: 160 IKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKIN---FSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRL 627
I++I + D L + L L G KI +++LD L+N++VLSI+ + I KIE L L NL+ELYLS N I ++GLEN L LD+ N++ I + +LT++ + N ++ ++ +L K L + + NP+ YR I++ L
Sbjct: 223 IRVIENLDGLTSLTSLFL----GTNKINKLQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEGLENNKKLTTLDIAANRVKKIEN-----ISHLTELQEFWMNDNQIENWSDLDELKNAKSLETVYLERNPLQKDPQYRRKIMLAL 372 HSP 2 Score: 57.7658 bits (138), Expect = 7.614e-8 Identity = 46/136 (33.82%), Postives = 73/136 (53.68%), Query Frame = 1
Query: 142 YITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLK 549
++ I IA+ +H ++ L L G +IR IE+LD L ++T L + + I K++ LD L NL L + N+I +++GL+NL+NLK L + N + I K LT ++ + N IE IS L L+
Sbjct: 195 FLVHNKITGIANLEHFSFLEMLEL----GSNRIRVIENLDGLTSLTSLFLGTNKINKLQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEG--LENNKKLTTLDIAANRVKKIENISHLTELQ 324
BLAST of centriolin vs. Ensembl Medaka
Match: lrguk (leucine rich repeats and guanylate kinase domain containing [Source:NCBI gene;Acc:101165778]) HSP 1 Score: 59.6918 bits (143), Expect = 3.085e-8 Identity = 50/165 (30.30%), Postives = 90/165 (54.55%), Query Frame = 1
Query: 235 KIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSR 729
I I L+ +T LS+ + I +I LD L L L L N++ ++DGLEN+ +L++LD+ N++ + + + L IN +N I+E + L L DL++ ENP+ +YRL ++ L++L +LD V A+EK + +++ +D +++R
Sbjct: 127 SISEITGLEQCYRLTHLSLAHNKISRISGLDGL-PLTYLCLRGNQLQKIDGLENVKSLQVLDLSLNRVTCL--TGLQSLQLLCSINLEKNQISEIDECKHIHNLLLLRDLNLLENPLQEQPNYRLAVIFLLQHLTMLDQEVVTAEEKVTSANKYDP-PMDLVAAR 287
BLAST of centriolin vs. Ensembl Medaka
Match: drc3 (dynein regulatory complex subunit 3 [Source:NCBI gene;Acc:101162841]) HSP 1 Score: 54.6842 bits (130), Expect = 9.904e-7 Identity = 51/174 (29.31%), Postives = 90/174 (51.72%), Query Frame = 1
Query: 238 IRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEE 759
I+ I+ L ++ L + + I+KI+ LD L NL L LS N+I ++ GL +L LK+L++ NQ+ I + T LT N+ + +E + L K L+ + + N + Y+ +IV L +LDN+ +L + K+ A +++++ R E++KQL E
Sbjct: 48 IQRIDSLQEYTSLVRLDLNNNLIKKIQGLDSLINLTWLNLSFNRIEKIQGLTSLQKLKVLNLSNNQITVIENMDT--LDNLTHFFIGCNLLNQLENVLYLKRFKKLVHIYMKGNLFSNEDDYQFFIVAFFPNLTVLDNKLILQELKEKASSKYQDDIEKRNQE---ESQKQLAE 216
BLAST of centriolin vs. Ensembl Medaka
Match: lrrc23 (leucine rich repeat containing 23 [Source:NCBI gene;Acc:105354421]) HSP 1 Score: 53.5286 bits (127), Expect = 1.273e-6 Identity = 44/137 (32.12%), Postives = 72/137 (52.55%), Query Frame = 1
Query: 268 NNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTL-KXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEK 675
N+ L +R + +E + L+ L NL+ LYL++N I L+GL+ L +L IL +R N+L ++ + K L +N N+ + + + + K L L +SENP+ A A YR ++ L L LD V E+
Sbjct: 165 GNLLTLELRGNHLETTDGLN-LPNLQRLYLADNGIKHLEGLDKLESLAILHIRDNKLETL-EGLSPNMKCLQYLNVRGNLIAEEKALQSIGLVAKSLQALVLSENPLVATADYRPNVLTLLPQLKRLDKEPVTPAER 299
BLAST of centriolin vs. Planmine SMEST
Match: SMESG000006866.1 (SMESG000006866.1) HSP 1 Score: 4118.15 bits (10679), Expect = 0.000e+0 Identity = 2141/2158 (99.21%), Postives = 2145/2158 (99.40%), Query Frame = 1
Query: 121 MNPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQXXXXXXXXXXXXXXXXXXXFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQFITKKEVEMLMERKRMKQGHSKKEQEENNGRNSTQKLKEDFVDSLNEKVKEKLTELNQINKEISEKNKIVDNLNNNIDHKELFYDSNTPTKSLIPNFHRADRPRSALASFXXXXXXXXXXXXXXXXXETESINKHNEHSNTTDLFLEKVENLTEMQREAEELRRQMESTEKESNRQQKDIEFLRSQFEKFKVADPNLANHIENEMKEKELHVDENLKLYDNLSKRLDQLSMEIEKSMNDIKEIEAKLLEENVFFTNDMKDKINTALSQLTQSVPNRINQDFKKVLDKCKYAEFENQKLQQKLIDQSKEIDALQHQLQNEGALSSRRSARSIDDEVEILRKELNRLRQDAVAAKDDLESEIEMEKVVNDXXXXXXXXXXXXXXXXXXXXXXXXXKHEKLIDQMKGDHYLMQEAIEREMMNFQDNVMHRIKIAASENQIEHLEKSKNPIDKALLNLIKSTTIEDKPPDTPADPEISKITEDLDHIKIQLTDINRKISIPSTITPLETSIGPKGFSRERDSQTLPIKKMLSKSNEIYKDELNDMKSKIRSLQDSLSKAMKMRKAQNKHKPSTNIKFTPKMSKETLYDISSSEDIQSTPKVRAHSQDRIPRKFKSVTPTAKKWNSMQQNISSDEQRVFDAIQDELQELIQHLNLSEYRNNQRIEEAMNRLSGFEHEYQSSREDRFSKERYDHIDQEKENLEEFLRETMSRVERCQEDIKQLNDKLGSNFRNSKQESDNNTYTSEMEKMAGILQSQKAEIERLNTILENLMKSAPSNNPQFVQQQAMPPNNSPLPGATYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIVIFGRFLDKESTCLAQEHFIEQQNLFKEYMQPNNSRISSNWENNGKAPGNDLPIGVESAILAEHQRHXXXXXXXXKDNIASATQASQNAQFNFDTLSGNKTFDNNLKWNTGSSGLGSTLDHTGNSLDTFENEKLKKALHSQFNEDVEKINSENSKSEIRCHQLRAEIDNLKSDFPSDKFPLSQSD 6594
MNPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKDLLDLDVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQLEENLKSKDLLLKKKSEDLFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQFITKKEVEMLMERKRMKQGHSKKEQEENNGRNSTQKLKEDFVDSLNEKVKEKLTELNQINKEISEKNKIVDNLNNNIDHKELFYDSNTPTKSLIPNFHRADRPRSALASFNRLSPLRTLLNRPRRLSETESINKHNEHSNTTDLFLEKVENLTEMQREAEELRRQMESTEKESNRQQKDIEFLRSQFEKFKVADPNLANHIENEMKEKELHVDENLKLYDNLSKRLDQLSMEIEKSMNDIKEIEAKLLEENVFFTNDMKDKINTALSQLTQSVPNRINQDFKKVLDKCKYAEFENQKLQQKLIDQSKEIDALQHQLQNEGALSSRRSARSIDDEVEILRKELNRLRQDAVAAKDDLESEIEMEKVVNDELQKQLEELKQNEEILTENLEILQNKHEKLIDQMKGDHYLMQEAIEREMMNFQDNVMHRIKIAASENQIEHLEKSKNPIDKALLNLIKSTTIEDKPPDTPADPEISKITEDLDHIKIQLTDINRKISIPSTITPLETSIGPKGFSRERDSQTLPIKKMLSKSNEIYKDELNDMKSKIRSLQDSLSKAMKMRKAQNKHKPSTNIKFTPKMSKETLYDISSSEDIQSTPKVRAHSQDRIPRKFKSVTPTAKKWNSMQQNISSDEQRVFDAIQDELQELIQHLNLSEYRNNQRIEEAMNRLSGFEHEYQSSREDRFSKERYDHIDQEKENLEEFLRETMSRVERCQEDIKQLNDKLGSNFRNSKQESDNNTYTSEMEKMAGILQSQKAEIERLNTILENLMKSAPSNNPQFVQQQAMPPNNSPLPGATYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHK+NEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFTQIQEQTTETLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEI+KIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKER+IMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNR CLAQEHFIEQQNLFKEYMQPNNSRISSNWENNGKAPGNDLPIGVESAILAEHQRHLQNQLNLLKDNIASATQASQNAQFNFDTLSGNKTFDNNLKWNTGSSGLGSTLDHTGNSLDTFENEKLKKALHSQFNED+EKINSENSKSEIRCHQLRAEIDNLKSDFPSDKFPLSQSD
Sbjct: 1 MNPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKDLLDLDVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQIKQLEENLKSKDLLLKKKSEDLFRACQKYYELEQDIAFIKIDAKFDLLSNHIGPLEEPDNMSEHSQISSTGDQAYMGKGQFITKKEVEMLMERKRMKQGHSKKEQEENNGRNSTQKLKEDFVDSLNEKVKEKLTELNQINKEISEKNKIVDNLNNNIDHKELFYDSNTPTKSLIPNFHRADRPRSALASFNRLSPLRTLLNRPRRLSETESINKHNEHSNTTDLFLEKVENLTEMQREAEELRRQMESTEKESNRQQKDIEFLRSQFEKFKVADPNLANHIENEMKEKELHVDENLKLYDNLSKRLDQLSMEIEKSMNDIKEIEAKLLEENVFFTNDMKDKINTALSQLTQSVPNRINQDFKKVLDKCKYAEFENQKLQQKLIDQSKEIDALQHQLQNEGALSSRRSARSIDDEVEILRKELNRLRQDAVAAKDDLESEIEMEKVVNDELQKQLEELKQNEEILTENLEILQNKHEKLIDQMKGDHYLMQEAIEREMMNFQDNVMHRIKIAASENQIEHLEKSKNPIDKALLNLIKSTTIEDKPPDTPADPEISKITEDLDHIKIQLTDINRKISIPSTITPLETSIGPKGFSRERDSQTLPIKKMLSKSNEIYKDELNDMKSKIRSLQDSLSKAMKMRKAQNKHKPSTNIKFTPKMSKETLYDISSSEDIQSTPKVRAHSQDRIPRKFKSVTPTAKKWNSMQQNISSDEQRVFDAIQDELQELIQHLNLSEYRNNQRIEEAMNRLSGFEHEYQSSREDRFSKERYDHIDQEKENLEEFLRETMSRVERCQEDIKQLNDKLGSNFRNSKQESDNNTYTSEMEKMAGILQSQKAEIERLNTILENLMKSAPSNNPQFVQQQAMPPNNSPLPGATYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKKNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFTQIQEQTTETLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEINKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERVIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNR-------------CLAQEHFIEQQNLFKEYMQPNNSRISSNWENNGKAPGNDLPIGVESAILAEHQRHLQNQLNLLKDNIASATQASQNAQFNFDTLSGNKTFDNNLKWNTGSSGLGSTLDHTGNSLDTFENEKLKKALHSQFNEDIEKINSENSKSEIRCHQLRAEIDNLKSDFPSDKFPLSQSD 2145
BLAST of centriolin vs. Planmine SMEST
Match: SMESG000006866.1 (SMESG000006866.1) HSP 1 Score: 2465.26 bits (6388), Expect = 0.000e+0 Identity = 1240/1257 (98.65%), Postives = 1244/1257 (98.97%), Query Frame = 1
Query: 2824 MSKETLYDISSSEDIQSTPKVRAHSQDRIPRKFKSVTPTAKKWNSMQQNISSDEQRVFDAIQDELQELIQHLNLSEYRNNQRIEEAMNRLSGFEHEYQSSREDRFSKERYDHIDQEKENLEEFLRETMSRVERCQEDIKQLNDKLGSNFRNSKQESDNNTYTSEMEKMAGILQSQKAEIERLNTILENLMKSAPSNNPQFVQQQAMPPNNSPLPGATYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKRNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFXXXXXXXXXXLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEIDKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERLIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNRIVIFGRFLDKESTCLAQEHFIEQQNLFKEYMQPNNSRISSNWENNGKAPGNDLPIGVESAILAEHQRHXXXXXXXXKDNIASATQASQNAQFNFDTLSGNKTFDNNLKWNTGSSGLGSTLDHTGNSLDTFENEKLKKALHSQFNEDVEKINSENSKSEIRCHQLRAEIDNLKSDFPSDKFPLSQSD 6594
MSKETLYDISSSEDIQSTPKVRAHSQDRIPRKFKSVTPTAKKWNSMQQNISSDEQRVFDAIQDELQELIQHLNLSEYRNNQRIEEAMNRLSGFEHEYQSSREDRFSKERYDHIDQEKENLEEFLRETMSRVERCQEDIKQLNDKLGSNFRNSKQESDNNTYTSEMEKMAGILQSQKAEIERLNTILENLMKSAPSNNPQFVQQQAMPPNNSPLPGATYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHK+NEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFTQIQEQTTETLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEI+KIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKER+IMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNR CLAQEHFIEQQNLFKEYMQPNNSRISSNWENNGKAPGNDLPIGVESAILAEHQRHLQNQLNLLKDNIASATQASQNAQFNFDTLSGNKTFDNNLKWNTGSSGLGSTLDHTGNSLDTFENEKLKKALHSQFNED+EKINSENSKSEIRCHQLRAEIDNLKSDFPSDKFPLSQSD
Sbjct: 1 MSKETLYDISSSEDIQSTPKVRAHSQDRIPRKFKSVTPTAKKWNSMQQNISSDEQRVFDAIQDELQELIQHLNLSEYRNNQRIEEAMNRLSGFEHEYQSSREDRFSKERYDHIDQEKENLEEFLRETMSRVERCQEDIKQLNDKLGSNFRNSKQESDNNTYTSEMEKMAGILQSQKAEIERLNTILENLMKSAPSNNPQFVQQQAMPPNNSPLPGATYIPNGFLPQIHNSHSTPILNTVPYSSIVTSEMKNAGSLFCNVPEHHYLEDHFQNNGKHKSSWKLKQKFKSDSEKYMMTLDSLKEDIHKKNEDLDNVEIQISKQTNEIGRLNYQIDQLNYTKQDLLNNISSLREETEFVTRETIASTSESLGHMRARKSQLSDEINKMDSLIREKKDELYRADNELKNSKIYFTQIQEQTTETLIKHDDARKNHKKVILECEELEKKSREASLELAKAMNELNIVQNETSKLTSSKMNLEEVVVKIQSIINQKDNEFQKINEEISRAAHQLNSLKSDLNMATEQNREKMQMLSEGDQLLSDTRLELNRLKNEVVLNQEHLQKMESDIGERNAAIDIANSEIERSRQVHNRLIQEYQSEQARIKREFSDLKFELENLKDEKNDLMCTIENSRMKNIQMKENIDKQEQSQMVLQSELEKLNCQTQHIDSMLRMKQGQLDKVLAEYQSRLVDLERIDEETHKQHVESKKLDADIKRKATEINKIRQTIAIDSEGFQRLQFDKESIEMSISTLSKEKSILQNEKKELESNLKILRKQESQVHETLTALEAKVSQSRTELEKMHSEKCSETIKRDELKTQSNSVSKQLHESKCELQSIKERVIMIEAQCDERTSEIRKKMQLQSNLNIEIRKLQDQIRLANISFDELNSEAQRRKEKCNGLDKEITKKNDEIKLLEKKIFDLQNNVSKEDNKLEKILKNSSFELAQLKSEITEKLENLEASGTKLHQLKKDAAIKEFTEQKIFELEEIIKQQENNAHHYEQENRKLSNHLAVINRDLAALRQNHQFEMDNKDKELSRLRKRVAKEIFQLEKLAEDQCNRANSLSDDLNQARRDYMLLRNR-------------CLAQEHFIEQQNLFKEYMQPNNSRISSNWENNGKAPGNDLPIGVESAILAEHQRHLQNQLNLLKDNIASATQASQNAQFNFDTLSGNKTFDNNLKWNTGSSGLGSTLDHTGNSLDTFENEKLKKALHSQFNEDIEKINSENSKSEIRCHQLRAEIDNLKSDFPSDKFPLSQSD 1244
BLAST of centriolin vs. Planmine SMEST
Match: SMESG000013624.1 (SMESG000013624.1) HSP 1 Score: 68.9366 bits (167), Expect = 1.227e-11 Identity = 54/162 (33.33%), Postives = 86/162 (53.09%), Query Frame = 1
Query: 274 ITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEE 759
+ L +R + + + + L+ L+LS+N+I ++ GLENL++L +L +R N+L+ + FT + L +N N +IEEI KL L L L +S NPVA + YRL + L+ L+ LD L DE++ EQ + R+ +LE K E
Sbjct: 184 LVSLELRGNRLTDTSGFENMGKLKNLFLSKNQITKICGLENLISLSVLHLRDNELSEL-EGFTDDLQSLQYLNLRGNHVQAIEEIKKLKQLSLLRALILSGNPVAELDEYRLETLTTLRKLVRLDKDNFL-DEERTEAEQIYK---QRLHDEMLENRKSFTE 340
BLAST of centriolin vs. Planmine SMEST
Match: SMESG000011491.1 (SMESG000011491.1) HSP 1 Score: 64.6994 bits (156), Expect = 7.286e-10 Identity = 55/211 (26.07%), Postives = 100/211 (47.39%), Query Frame = 1
Query: 226 GDKKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRLLETEKQLEEMKENQLKLQKDHAKQDQYQKDLNKKQKSNIEQI 858
G +I IE L++L + VL + ++I+ IE ++ L +LR L L+ N I L L L +L +++R N + S+ + C L +I S N I + S L L L +L + NP+++ R ++ L +LD +++ D++ A + EL S+ L Q + + Q +H ++ K+ K +N ++I
Sbjct: 173 GRNRISKIEGLESLTRLDVLDLHANSIQVIENINHLSDLRVLNLAGNVITCLTNLRGLYSLSEVNIRRNCVESVIDINSTNCPNLQRIFLSFNHLGRISDFSCLIDLGSLNELSIDNNPISSNGSSRSAVIFNFPQLNLLDTKQITEDDRNKAKQIINRLELGSKSNSGLSRHIQGNNSRTSNSSQQSNHIQRFHSLKERQKGSLNNSQRI 383
BLAST of centriolin vs. Planmine SMEST
Match: SMESG000061668.1 (SMESG000061668.1) HSP 1 Score: 60.077 bits (144), Expect = 8.241e-9 Identity = 53/155 (34.19%), Postives = 80/155 (51.61%), Query Frame = 1
Query: 232 KKIRYIEHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHWFTRRCKYLTKINFSRNMFDSIEEISKLWTLKXXXXXXVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQF 696
K I I +L ++T L + + IEKIE LD+L +L L LS NKI ++GLENL+ L L + N++N I + K L +F +N+ SIE + L K L L++S NP+ Y +I L+ LD + V E + E++
Sbjct: 72 KNILKINNLWAFKSLTKLQLVNNIIEKIENLDRLVHLEWLDLSFNKIEVIEGLENLVKLTDLSLYCNRINVIEN--MDNLKELNVFSFGKNLLTSIENVLYLRKFKKLQSLNLSGNPICHSDEYFSFIFAFFPNLMFLDYKLVTKMEHQACYEKY 224 The following BLAST results are available for this feature:
BLAST of centriolin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of centriolin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of centriolin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of centriolin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of centriolin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of centriolin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of centriolin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of centriolin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of centriolin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of centriolin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of centriolin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of centriolin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of centriolin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of centriolin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012954 ID=SMED30012954|Name=centriolin|organism=Schmidtea mediterranea sexual|type=transcript|length=6702bpback to top protein sequence of SMED30012954-orf-1 >SMED30012954-orf-1 ID=SMED30012954-orf-1|Name=SMED30012954-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2159bp MNPPGVRYITEEFIKIIAHEDHLDRIKKLNLDCGKGDKKIRYIEHLDNLNback to top Aliases
The feature 'centriolin' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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