trimeric intracellular cation channel type 1B.1 isoform X1

Overview


Name	trimeric intracellular cation channel type 1B.1 isoform X1
Smed ID	SMED30012938
Length (bp)	1213

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of trimeric intracellular cation channel type 1B.1 isoform X1 (SMED30012938) t-SNE clustered cells

Violin plots show distribution of expression levels for trimeric intracellular cation channel type 1B.1 isoform X1 (SMED30012938) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of trimeric intracellular cation channel type 1B.1 isoform X1 (SMED30012938) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012938

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30012938	h1SMcG0011811	dd_Smed_v4_3001_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30012938	h1SMcG0011811	dd_Smed_v4_3001_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior side	SMED30012938	h1SMcG0011811	dd_Smed_v4_3001_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30012938	h1SMcG0011811	dd_Smed_v4_3001_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30012938	h1SMcG0011811	dd_Smed_v6_3001_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30012938	h1SMcG0011811	OX_Smed_1.0.19304	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
Match: TMEM38B (transmembrane protein 38B [Source:HGNC Symbol;Acc:HGNC:25535])

HSP 1 Score: 114.39 bits (285), Expect = 2.178e-28
Identity = 68/248 (27.42%), Postives = 125/248 (50.40%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRV-SSILVGIKDPFLPFETLICGIFFG 791
            MD+ + D +A    +  MFP+F+I HYL+  + +++  PG  A + ++P++SW   +L CF G  +S   + EP +  L  H N++ AS  WY+  + P DLV +  S++PV L+ S  KE+ RT  +  G+  A   + + ++V +++G A+G G  I         G  +  G+  L  ++  K +L  +++F  +  Q + +    +     IF++  ++           F PFE  +  + FG
Sbjct:    1 MDSPW-DELALAFSRTSMFPFFDIAHYLVSVMAVKR-QPGAAALAWKNPISSWFTAMLHCFGGGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEVTRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTLSWMLFG 246

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
Match: TMEM38A (transmembrane protein 38A [Source:HGNC Symbol;Acc:HGNC:28462])

HSP 1 Score: 112.849 bits (281), Expect = 7.927e-28
Identity = 66/235 (28.09%), Postives = 119/235 (50.64%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRV-SSILVGIKDPFLPFETLICGIFFGG 794
            ++ +FP F++  Y I+S+   +  PG    SR+HP+ASW   +L CF    +++  +GEPL+     + +++ AS  WYL+ + P DL +K   F+PV L+    KE+ R + + +GI  A   +   + V ++ G  KG G  +         G  +   N +L+ +F  K SL  AI+F +++ + +P+  + +     +F++  +V  +       PF   E  IC + FG 
Sbjct:   18 RVPLFPVFDLS-YFIVSILYLKYEPGAVELSRRHPIASWLCAMLHCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFVMIATGWVKGSGVALMSNFEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTLFMVSCKVFLTATHSHSSPFDALEGYICPVLFGS 251

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
Match: TMEM38B (transmembrane protein 38B [Source:HGNC Symbol;Acc:HGNC:25535])

HSP 1 Score: 81.2629 bits (199), Expect = 6.043e-17
Identity = 50/192 (26.04%), Postives = 91/192 (47.40%), Query Frame = 3

Query:  219 ILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRV-SSILVGIKDPFLPFETLICGIFFG 791
            +L CF G  +S   + EP +  L  H N++ AS  WY+  + P DLV +  S++PV L+ S  KE+ RT  +  G+  A   + + ++V +++G A+G G  I         G  +  G+  L  ++  K +L  +++F  +  Q + +    +     IF++  ++           F PFE  +  + FG
Sbjct:    1 MLHCFGGGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEVTRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTLSWMLFG 192

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
Match: TMEM38A (transmembrane protein 38A [Source:HGNC Symbol;Acc:HGNC:28462])

HSP 1 Score: 75.485 bits (184), Expect = 3.531e-16
Identity = 37/108 (34.26%), Postives = 63/108 (58.33%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKEL 416
            ++ +FP F++  Y I+S+   +  PG    SR+HP+ASW   +L CF    +++  +GEPL+     + +++ AS  WYL+ + P DL +K   F+PV L+    KE+
Sbjct:    4 RVPLFPVFDL-SYFIVSILYLKYEPGAVELSRRHPIASWLCAMLHCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEV 110

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
Match: TMEM38B (transmembrane protein 38B [Source:HGNC Symbol;Acc:HGNC:25535])

HSP 1 Score: 65.4698 bits (158), Expect = 4.368e-12
Identity = 40/153 (26.14%), Postives = 75/153 (49.02%), Query Frame = 3

Query:  249 SNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLI 707
            S   + EP +  L  H N++ AS  WY+  + P DLV +  S++PV L+ S  KE+ RT  +  G+  A   + + ++V +++G A+G G  I         G  +  G+  L  ++  K +L  +++F  +  Q + +    +     IF++
Sbjct:    2 SCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEVTRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIV 154

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Celegans
Match: tric-1B.1 (Trimeric intracellular cation channel type 1B.1 [Source:UniProtKB/Swiss-Prot;Acc:Q9NA75])

HSP 1 Score: 192.586 bits (488), Expect = 2.774e-58
Identity = 93/263 (35.36%), Postives = 160/263 (60.84%), Query Frame = 3

Query:   87 LYQLEMFPYFNICHYLIISLHMRQ-IAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANN 869
            L++L+M+PYF++ HYL++ + +R  +      FSR+HPL+ W +++LMCFA +F++NF +GEP++ P K H+++I A++ WYL+ Y PFD ++KI    PV  V+++ KE+ R   V  G++ AAK +P+S++V + VG AKG G  I   +     G    + N LL P+F  K  +  A +  +EK    +      ++L  V F +YF++S++++ + DPF P E L C IF GG+ + +       AA ++++   A++
Sbjct:   21 LHRLKMYPYFDVAHYLLMIIEVRDDLGSAASIFSRKHPLSCWLSSMLMCFADAFLANFLLGEPVIAPFKRHDDIILATIIWYLVFYAPFDGIYKIAKITPVKCVLAVMKEVKRAYKVSHGVSHAAKLYPNSYIVQVLVGTAKGAGSGIVRTLEQLVRGVWLPTHNELLRPSFATKACVVAASVLALEKSGTYLTAPHDLVYLVIVGFFVYFKLSAVILHVTDPFAPIENLFCAIFMGGIWDAV---SRALAASRDRRAAGAHS 280

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Celegans
Match: tric-1B.2 (Trimeric intracellular cation channel type 1B.2 [Source:UniProtKB/Swiss-Prot;Acc:Q9NA73])

HSP 1 Score: 188.348 bits (477), Expect = 2.049e-56
Identity = 93/283 (32.86%), Postives = 168/283 (59.36%), Query Frame = 3

Query:   36 NH*SIMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQ-IAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKE--KQAAEKNKKYTEANNL 872
            +H +++DA        Y+ +L+++PYF+  HY++  L +R  + P   +FSR+HP + W + +LM FAGSF+S F +GEP++ PLK H +++  S+ WYL+ Y PFD+VF++ ++ PV L +S+ KE+ RT  +  G+  A + +P+S+LV + VG+AKG G  +   +     G    + + +L P+F  K  +  +I+F +E+    V      ++L  V F IYF+++S+ + + D  +P E ++C +F GG+++   +  +  K+A   N+  +E   L
Sbjct:   11 DHDTLIDA------GGYVQKLKLYPYFDAAHYVLTCLSVRHDLGPDAISFSRKHPFSCWLSCMLMSFAGSFLSCFLLGEPIISPLKQHADILLGSIVWYLVFYSPFDVVFRLATWFPVKLGLSVLKEVQRTHKIAAGVKHAVRIYPESYLVQILVGVAKGAGSGVVKIVEQLARGTWHPTNHEILRPSFTTKACVIASIVFTLERHSMYVTAPHDLVYLCVVGFFIYFKLASLCLSVHDVLMPIENVLCAVFMGGIIDAFAKAVDATKKAIHSNRVLSEEEIL 287

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
Match: CG4239 (gene:FBgn0030745 transcript:FBtr0074269)

HSP 1 Score: 198.749 bits (504), Expect = 8.940e-61
Identity = 103/268 (38.43%), Postives = 165/268 (61.57%), Query Frame = 3

Query:   75 VAKYLYQLEMFPYFNICHYLIISLHMRQIAPGN-KAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETL-KEMKEKQAAEKNKKYTEANN 869
            VA  + +L+MFP+F+I H L+ +L +R+    N +AFSR+HPLA W +T+L+ FAG  ++N  +GEP++ PLK    L+  +  WY++ Y PFD+ +K+  F+PV +V S  KE+YR K V+ G+  AAK +P+++++ + +G  KG G      I     G    +    + P+F  K SL  +I+F ++K    +    + ++   VIFL+YF++SSIL+GI DPFLP E L C IFFGG+ ++L K +   QA + + K  + +N
Sbjct:    9 VANQVIKLKMFPFFDIAHSLLAALAVREDLGANAQAFSRKHPLACWLSTMLVIFAGGMVANGLLGEPILAPLKNTGQLLVGTAVWYVVFYTPFDIGYKVAKFLPVKIVASAMKEIYRAKKVYDGVGHAAKLYPNAWIIMIIIGTLKGNGAGFTKLIERLIRGAWTPTAMEFMQPSFYTKASLLASIIFVLDKKTDWISAPHALVYFGIVIFLVYFKLSSILLGIHDPFLPLENLCCAIFFGGIWDSLAKILGRGQAKDGDSKDVKKSN 276

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
Match: CG4239 (gene:FBgn0030745 transcript:FBtr0340314)

HSP 1 Score: 198.749 bits (504), Expect = 8.940e-61
Identity = 103/268 (38.43%), Postives = 165/268 (61.57%), Query Frame = 3

Query:   75 VAKYLYQLEMFPYFNICHYLIISLHMRQIAPGN-KAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETL-KEMKEKQAAEKNKKYTEANN 869
            VA  + +L+MFP+F+I H L+ +L +R+    N +AFSR+HPLA W +T+L+ FAG  ++N  +GEP++ PLK    L+  +  WY++ Y PFD+ +K+  F+PV +V S  KE+YR K V+ G+  AAK +P+++++ + +G  KG G      I     G    +    + P+F  K SL  +I+F ++K    +    + ++   VIFL+YF++SSIL+GI DPFLP E L C IFFGG+ ++L K +   QA + + K  + +N
Sbjct:    9 VANQVIKLKMFPFFDIAHSLLAALAVREDLGANAQAFSRKHPLACWLSTMLVIFAGGMVANGLLGEPILAPLKNTGQLLVGTAVWYVVFYTPFDIGYKVAKFLPVKIVASAMKEIYRAKKVYDGVGHAAKLYPNAWIIMIIIGTLKGNGAGFTKLIERLIRGAWTPTAMEFMQPSFYTKASLLASIIFVLDKKTDWISAPHALVYFGIVIFLVYFKLSSILLGIHDPFLPLENLCCAIFFGGIWDSLAKILGRGQAKDGDSKDVKKSN 276

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
Match: CG4239 (gene:FBgn0030745 transcript:FBtr0074270)

HSP 1 Score: 198.749 bits (504), Expect = 8.940e-61
Identity = 103/268 (38.43%), Postives = 165/268 (61.57%), Query Frame = 3

Query:   75 VAKYLYQLEMFPYFNICHYLIISLHMRQIAPGN-KAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETL-KEMKEKQAAEKNKKYTEANN 869
            VA  + +L+MFP+F+I H L+ +L +R+    N +AFSR+HPLA W +T+L+ FAG  ++N  +GEP++ PLK    L+  +  WY++ Y PFD+ +K+  F+PV +V S  KE+YR K V+ G+  AAK +P+++++ + +G  KG G      I     G    +    + P+F  K SL  +I+F ++K    +    + ++   VIFL+YF++SSIL+GI DPFLP E L C IFFGG+ ++L K +   QA + + K  + +N
Sbjct:    9 VANQVIKLKMFPFFDIAHSLLAALAVREDLGANAQAFSRKHPLACWLSTMLVIFAGGMVANGLLGEPILAPLKNTGQLLVGTAVWYVVFYTPFDIGYKVAKFLPVKIVASAMKEIYRAKKVYDGVGHAAKLYPNAWIIMIIIGTLKGNGAGFTKLIERLIRGAWTPTAMEFMQPSFYTKASLLASIIFVLDKKTDWISAPHALVYFGIVIFLVYFKLSSILLGIHDPFLPLENLCCAIFFGGIWDSLAKILGRGQAKDGDSKDVKKSN 276

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
Match: CG4239 (gene:FBgn0030745 transcript:FBtr0074268)

HSP 1 Score: 198.749 bits (504), Expect = 8.940e-61
Identity = 103/268 (38.43%), Postives = 165/268 (61.57%), Query Frame = 3

Query:   75 VAKYLYQLEMFPYFNICHYLIISLHMRQIAPGN-KAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETL-KEMKEKQAAEKNKKYTEANN 869
            VA  + +L+MFP+F+I H L+ +L +R+    N +AFSR+HPLA W +T+L+ FAG  ++N  +GEP++ PLK    L+  +  WY++ Y PFD+ +K+  F+PV +V S  KE+YR K V+ G+  AAK +P+++++ + +G  KG G      I     G    +    + P+F  K SL  +I+F ++K    +    + ++   VIFL+YF++SSIL+GI DPFLP E L C IFFGG+ ++L K +   QA + + K  + +N
Sbjct:    9 VANQVIKLKMFPFFDIAHSLLAALAVREDLGANAQAFSRKHPLACWLSTMLVIFAGGMVANGLLGEPILAPLKNTGQLLVGTAVWYVVFYTPFDIGYKVAKFLPVKIVASAMKEIYRAKKVYDGVGHAAKLYPNAWIIMIIIGTLKGNGAGFTKLIERLIRGAWTPTAMEFMQPSFYTKASLLASIIFVLDKKTDWISAPHALVYFGIVIFLVYFKLSSILLGIHDPFLPLENLCCAIFFGGIWDSLAKILGRGQAKDGDSKDVKKSN 276

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
Match: CG33061 (gene:FBgn0053061 transcript:FBtr0113448)

HSP 1 Score: 72.0182 bits (175), Expect = 7.190e-14
Identity = 62/270 (22.96%), Postives = 118/270 (43.70%), Query Frame = 3

Query:   87 LYQLEMFPYFNICHYLIISLHMRQ-----------IAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVP----LGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKK 851
            L QL     F I HY +IS  +R               GNK    Q P   W A +L+ +AG  + N  +G   + PL    +++ +SL WY + Y PFDL   + S +   ++ +    + + +++  G+ +AA+ + ++ +  L VG   G G ++  P+A   +   + +    L  +   K +L ++++F +E + K P    +   Q+ +  ++    F+  S+           E  I    FGGL   L +  ++    K ++
Sbjct:    7 LRQLPNHLIFRILHYSLISQQLRDELVVSAGSFRLKGGGNKVLEWQ-PFVLWLANLLLNYAGDILGNLLLGSLPLEPLCNTADVMLSSLIWYCIFYCPFDLAHAVTSTLAFRILATAMSTISQVQLIDRGVHLAAQVYGNAPIPMLVVGTVMGSGAEVLKPVASLLINRCQHNQMAYLKLSNTSKVALFISLLFMLE-VYKSPIIMGINRHQLMVYILVMTTAFKFLSLCYRTDHIIWLLEQHIRYTLFGGLSRDLTKFFQRLLEPKVQR 274

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Zebrafish
Match: tmem38a (transmembrane protein 38A [Source:NCBI gene;Acc:393874])

HSP 1 Score: 109.768 bits (273), Expect = 7.450e-27
Identity = 72/257 (28.02%), Postives = 129/257 (50.19%), Query Frame = 3

Query:   48 IMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIH---ASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRV-SSILVGIKDPFLPFETLICGIFFGGLMET 806
            ++D      +A+Y  ++ MFP F++ +Y++  L+++   PG    SR+ P+ASW   +L CF    +++  +G   V P+ Y  N  H   AS  WYL+ + P +L +K  +F+PV LV+   KE+ RT+ +  G+  A   +   +L+ +  G  KG G  +         G  +   N +LN +F  K SL  AI+F +++   +P+  S +     +F++  +V  +       PF   E+ +C + FG  + T
Sbjct:    3 VLDVLNLGEIAQYFSKMAMFPVFDVAYYIVSILYLKY-EPGAVEVSRRSPVASWLCAMLYCFGSYILADIMLG---VCPIDYFHNNSHILLASAVWYLIFFCPLNLFYKCVAFMPVKLVLVALKEVVRTRKIAAGVHHAHHAYHHGWLIMVITGYVKGSGVALMSNFEQLLRGVWKPETNEVLNMSFPTKASLYGAILFTLQEAHVLPVSKSTLICLFTLFMVSSKVFMTARHSHGSPFALIESWVCHVLFGSPLGT 255

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Zebrafish
Match: CABZ01079427.1 (pep chromosome:GRCz11:21:566286:588858:-1 gene:ENSDARG00000100549.2 transcript:ENSDART00000168983.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01079427.1)

HSP 1 Score: 92.4337 bits (228), Expect = 8.691e-21
Identity = 59/235 (25.11%), Postives = 117/235 (49.79%), Query Frame = 3

Query:   87 LYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKD-PFLPFETLICGIFF 788
            L +L MFPYF++ HY+I  + +R+  PG+   S   PL    ++  + F G  +  F + +  ++ + +   ++      YL+ Y P D+V+ + S +P+ LV++  KE+ RT  V  G++ A  ++ D+  V ++VG AKG G  +         G  +   N LL  ++  K +L  A++F +++ + +P+ +  +     +F +  +   +L+G    P    E+ +    F
Sbjct:   16 LSKLPMFPYFDMAHYIISVMSLRE-QPGSLCVSTYSPLCCLFSSNNVAFGGLELLCFQLSDAALLLISHSRTVLLCVTKMYLVFYCPLDVVYSLASLLPLRLVLTAMKEVTRTWKVLSGVSQAGSKYSDALFVMVAVGWAKGAGGGLISNFEQLVRGVWKPETNELLKMSYPTKVTLLGAVVFSLQQCRYLPIQTHHLIFIYTLFTVTNKTRMMLLGSSSHPLSSLESFLYKTLF 249

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Xenopus
Match: tmem38b (transmembrane protein 38B [Source:NCBI gene;Acc:548881])

HSP 1 Score: 135.576 bits (340), Expect = 1.949e-36
Identity = 80/253 (31.62%), Postives = 132/253 (52.17%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILV-GIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNK 848
            QL MFP+F   HYL   +  R+ A      SR  PLASW +++L CF G  +S+  + EP V  L    ++I AS  WY++ YFP+DL +    F+P+ L+++  KE+ RT  +  G+A A   + D+ LV +++G A+G G  +         G  +   N  L  ++ VK +L  A++F ++  Q +P+    +     +FLI  +V+ +L      PFLP ET +  I F    +   E++E  ++  +K
Sbjct:   13 QLSMFPFFETAHYLTSVMSAREQAGAVDVASRS-PLASWFSSMLYCFGGGILSSILLAEPPVGILSNTTSIILASAVWYMVYYFPYDLFYNCFFFLPIRLILAGMKEVTRTWKILSGVAHAHSHYKDAMLVMITIGWARGAGGGLISNFEQLVRGVWKPESNEFLKMSYPVKVTLIGAVLFTLQHGQYLPISRHNLMFIYTLFLILIKVTMMLTRSTASPFLPLETSLQHILFSR-QQIPAEVRESPSSSGDK 263

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Xenopus
Match: tmem38a (transmembrane protein 38A [Source:NCBI gene;Acc:394592])

HSP 1 Score: 103.605 bits (257), Expect = 1.854e-24
Identity = 65/238 (27.31%), Postives = 122/238 (51.26%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFL----IYFRVSSILVGIKDPFLPFETLICGIFFGG 794
            +L +FP F++ +Y+I  L+++   PG    S++ P+ASW   +L CF    +++  +GE  +     + N++ AS  WYL  + P ++ +KI SF+P+ LV+   KE+ R + + +GI  A   +   +++ + +G  KG G  +   +     G  +   N +L+ +F  K SL  AI+F +++   +P+  + +     +F+    IY   +        PF  FE+ IC + FG 
Sbjct:   18 KLPVFPLFDVAYYIISILYLKY-EPGAVDLSKRSPVASWLCAMLYCFGSYILADVLLGESPIHYFSNNANILLASAVWYLTFFCPLNIFYKIVSFLPLKLVLVGMKEVVRVRKIAMGIHHAHHHYHHGWVIMVLIGWVKGSGVALMSNLEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQAHWLPISKAYLIFFFTLFMAICKIYMTATH---SHGSPFAIFESGICCVLFGA 251

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
Match: Tmem38a (transmembrane protein 38A [Source:MGI Symbol;Acc:MGI:1921416])

HSP 1 Score: 114.005 bits (284), Expect = 2.003e-28
Identity = 73/285 (25.61%), Postives = 133/285 (46.67%), Query Frame = 3

Query:   48 IMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRV-SSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANNLPPKCADGQG 899
            +M A     +A    ++ +FP F++  Y I+S+   +  PG    SR+HP+ASW   +L CF    +++  +GEP++       +++ AS  WYL+ + P DL +K   F+PV L+    KE+ R + + +GI  A   +   + + ++ G  KG G  +   +     G  +   N +L+ +F  K SL  AI+F +++ + +P+  + +     +F++  +V  +       PF   E  IC + FG             A       T+ + LP K  +  G
Sbjct:    3 LMSALSLGELALSFSRVPLFPVFDLS-YFIVSIIYLKYEPGAVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKGSGVALLSNVEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFVFTMFMVSCKVFLTATHSHSSPFDILEGYICPVLFGATWGGDHHHDNHGAPHGMGLGTQHSGLPAKAKEELG 286

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
Match: Tmem38b (transmembrane protein 38B [Source:MGI Symbol;Acc:MGI:1098718])

HSP 1 Score: 112.849 bits (281), Expect = 4.644e-28
Identity = 72/259 (27.80%), Postives = 130/259 (50.19%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKD---PFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTE 860
            +  MFP+F+I HYL+  + ++Q  PG  A +  +PLASW + +L CF G  +S   + E  +  L  H N++ AS  WY++ + P DLV +  S+ P+  + +  KE+ RT  +  G++ A   + ++++V + VG A+G G  +         G  +  G+  L  +F  K +L  +IMF  +  + + +    +     IFL+  +V+ ++   KD      PFE  +  + FG         +++Q    ++K TE
Sbjct:   14 RTSMFPFFDIAHYLVSVMALKQ-RPGAVAAAWNNPLASWLSAMLHCFGGGILSCMLLAESPLKFLTNHTNILLASSIWYIVFFCPRDLVSQGYSYQPIQFLAAGMKEVTRTWKIVGGVSDANSYYRNAWIVMIVVGWARGAGGAVVTACEQLLKGDWKPEGDEWLKMSFPCKITLLGSIMFTFQHTRHLAISKHDLMFLYTIFLVTIKVTMMMT--KDTAVTLTPFEDTLTRMLFG--------RRQQQQFSSSEKKTE 261

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
Match: Tmem38a (transmembrane protein 38A [Source:MGI Symbol;Acc:MGI:1921416])

HSP 1 Score: 82.4185 bits (202), Expect = 2.816e-18
Identity = 42/139 (30.22%), Postives = 76/139 (54.68%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAK 509
            ++ +FP F++  Y I+S+   +  PG    SR+HP+ASW   +L CF    +++  +GEP++       +++ AS  WYL+ + P DL +K   F+PV L+    KE+ R + + +GI  A   +   + + ++ G  K
Sbjct:   18 RVPLFPVFDL-SYFIVSIIYLKYEPGAVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVK 155

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
Match: Tmem38b (transmembrane protein 38B [Source:MGI Symbol;Acc:MGI:1098718])

HSP 1 Score: 70.8626 bits (172), Expect = 4.266e-14
Identity = 44/154 (28.57%), Postives = 78/154 (50.65%), Query Frame = 3

Query:  156 QIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSL 617
             +  G  A +  +PLASW + +L CF G  +S   + E  +  L  H N++ AS  WY++ + P DLV +  S+ P+  + +  KE+ RT  +  G++ A   + ++++V + VG A+G G  +         G  +  G+  L  +F  K +L
Sbjct:   10 SVLSGAVAAAWNNPLASWLSAMLHCFGGGILSCMLLAESPLKFLTNHTNILLASSIWYIVFFCPRDLVSQGYSYQPIQFLAAGMKEVTRTWKIVGGVSDANSYYRNAWIVMIVVGWARGAGGAVVTACEQLLKGDWKPEGDEWLKMSFPCKITL 163

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
Match: Tmem38a (transmembrane protein 38A [Source:MGI Symbol;Acc:MGI:1921416])

HSP 1 Score: 52.7582 bits (125), Expect = 3.000e-8
Identity = 27/93 (29.03%), Postives = 49/93 (52.69%), Query Frame = 3

Query:   48 IMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCW 326
            +M A     +A    ++ +FP F++  Y I+S+   +  PG    SR+HP+ASW   +L CF    +++  +GEP++       +++ AS  W
Sbjct:    3 LMSALSLGELALSFSRVPLFPVFDL-SYFIVSIIYLKYEPGAVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVW 94

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
Match: sp|Q9NA75|T38B1_CAEEL (Trimeric intracellular cation channel type 1B.1 OS=Caenorhabditis elegans OX=6239 GN=tric-1B.1 PE=1 SV=2)

HSP 1 Score: 192.586 bits (488), Expect = 3.529e-57
Identity = 93/263 (35.36%), Postives = 160/263 (60.84%), Query Frame = 3

Query:   87 LYQLEMFPYFNICHYLIISLHMRQ-IAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANN 869
            L++L+M+PYF++ HYL++ + +R  +      FSR+HPL+ W +++LMCFA +F++NF +GEP++ P K H+++I A++ WYL+ Y PFD ++KI    PV  V+++ KE+ R   V  G++ AAK +P+S++V + VG AKG G  I   +     G    + N LL P+F  K  +  A +  +EK    +      ++L  V F +YF++S++++ + DPF P E L C IF GG+ + +       AA ++++   A++
Sbjct:   21 LHRLKMYPYFDVAHYLLMIIEVRDDLGSAASIFSRKHPLSCWLSSMLMCFADAFLANFLLGEPVIAPFKRHDDIILATIIWYLVFYAPFDGIYKIAKITPVKCVLAVMKEVKRAYKVSHGVSHAAKLYPNSYIVQVLVGTAKGAGSGIVRTLEQLVRGVWLPTHNELLRPSFATKACVVAASVLALEKSGTYLTAPHDLVYLVIVGFFVYFKLSAVILHVTDPFAPIENLFCAIFMGGIWDAV---SRALAASRDRRAAGAHS 280

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
Match: sp|Q9NA73|T38B2_CAEEL (Trimeric intracellular cation channel type 1B.2 OS=Caenorhabditis elegans OX=6239 GN=tric-1B.2 PE=1 SV=2)

HSP 1 Score: 188.348 bits (477), Expect = 2.607e-55
Identity = 93/283 (32.86%), Postives = 168/283 (59.36%), Query Frame = 3

Query:   36 NH*SIMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQ-IAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQK-VPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKE--KQAAEKNKKYTEANNL 872
            +H +++DA        Y+ +L+++PYF+  HY++  L +R  + P   +FSR+HP + W + +LM FAGSF+S F +GEP++ PLK H +++  S+ WYL+ Y PFD+VF++ ++ PV L +S+ KE+ RT  +  G+  A + +P+S+LV + VG+AKG G  +   +     G    + + +L P+F  K  +  +I+F +E+    V      ++L  V F IYF+++S+ + + D  +P E ++C +F GG+++   +  +  K+A   N+  +E   L
Sbjct:   11 DHDTLIDA------GGYVQKLKLYPYFDAAHYVLTCLSVRHDLGPDAISFSRKHPFSCWLSCMLMSFAGSFLSCFLLGEPIISPLKQHADILLGSIVWYLVFYSPFDVVFRLATWFPVKLGLSVLKEVQRTHKIAAGVKHAVRIYPESYLVQILVGVAKGAGSGVVKIVEQLARGTWHPTNHEILRPSFTTKACVIASIVFTLERHSMYVTAPHDLVYLCVVGFFIYFKLASLCLSVHDVLMPIENVLCAVFMGGIIDAFAKAVDATKKAIHSNRVLSEEEIL 287

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
Match: sp|Q3KQE5|T38BA_XENLA (Trimeric intracellular cation channel type B-A OS=Xenopus laevis OX=8355 GN=tmem38b-a PE=2 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 8.304e-36
Identity = 76/252 (30.16%), Postives = 134/252 (53.17%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILV-GIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKN 845
            QL MFP+F++ HY++  +  R+ A G    + + P+ASW + +L CF G  +S+  + EP +  L    N++ AS  WY++ YFP+DL +    F+P+ L+I+  KE+ RT  +  G+  A   + D+ LV +++G A+G G  +         G  +   N  L  ++ VK +L  A++F ++    +P+    + L   +FL+  +V+ +L      PFLP ET +  I FG   +  K  + +Q+A  +
Sbjct:   13 QLSMFPFFDMAHYVVSVMSAREQA-GALDIAARSPMASWFSAMLYCFGGGILSSILLAEPPIAVLSNTTNIMLASTIWYMVYYFPYDLFYNCFFFLPIRLIIAGMKEVTRTWKILSGVTHAHSHYKDALLVMITIGWARGAGGGLISNFEQLVRGVWKPESNEFLKMSYPVKVTLIGAVLFTLQHGHYLPISRHNLMLIYTMFLVLIKVTMMLTHSTASPFLPLETPLQRILFG---QRQKPSEVRQSASSS 260

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
Match: sp|Q28FA9|TM38B_XENTR (Trimeric intracellular cation channel type B OS=Xenopus tropicalis OX=8364 GN=tmem38b PE=2 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 1.033e-35
Identity = 80/253 (31.62%), Postives = 132/253 (52.17%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILV-GIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNK 848
            QL MFP+F   HYL   +  R+ A      SR  PLASW +++L CF G  +S+  + EP V  L    ++I AS  WY++ YFP+DL +    F+P+ L+++  KE+ RT  +  G+A A   + D+ LV +++G A+G G  +         G  +   N  L  ++ VK +L  A++F ++  Q +P+    +     +FLI  +V+ +L      PFLP ET +  I F    +   E++E  ++  +K
Sbjct:   13 QLSMFPFFETAHYLTSVMSAREQAGAVDVASRS-PLASWFSSMLYCFGGGILSSILLAEPPVGILSNTTSIILASAVWYMVYYFPYDLFYNCFFFLPIRLILAGMKEVTRTWKILSGVAHAHSHYKDAMLVMITIGWARGAGGGLISNFEQLVRGVWKPESNEFLKMSYPVKVTLIGAVLFTLQHGQYLPISRHNLMFIYTLFLILIKVTMMLTRSTASPFLPLETSLQHILFSR-QQIPAEVRESPSSSGDK 263

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
Match: sp|Q6GN30|T38BB_XENLA (Trimeric intracellular cation channel type B-B OS=Xenopus laevis OX=8355 GN=tmem38b-b PE=1 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 6.607e-35
Identity = 78/253 (30.83%), Postives = 132/253 (52.17%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILV-GIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNK 848
            QL MFP+F++ HYL   +  R+ A G    +   P+ASW + +L CF G  +S+  + EP V  L    N++ AS  WY++ YFP+DL +    F+P+ L+ +  KE+ RT  +  GI  A   + D++LV +++G A+G G  +         G  +   N  L  ++ VK +L  A++F ++    +P+    +     +FL+  +V+ +L      PFLP ET +  I F GL +   E++E  ++   K
Sbjct:   13 QLSMFPFFDMAHYLASVMSAREQA-GALDIASHSPMASWFSAMLHCFGGGILSSILLAEPPVGILANTTNIMLASAIWYMVYYFPYDLFYNCFFFLPIRLIAAGMKEVTRTWKILSGITHAHSHYKDAWLVMITIGWARGAGGGLISNFEQLVRGVWKPESNEFLKMSYPVKVTLIGAVLFTLQHGHYLPISRHNLMFIYTMFLVSIKVTMMLTHSAGSPFLPLETPLHRILF-GLRQNQAEVRESPSSSGAK 263

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
Match: A0A1S3IM38 (trimeric intracellular cation channel type 1B.1 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106165051 PE=4 SV=1)

HSP 1 Score: 236.498 bits (602), Expect = 7.666e-72
Identity = 106/274 (38.69%), Postives = 179/274 (65.33%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAP--GNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEAN 866
            MD +    +A  + +L+M+PYF++CHY++++L +R+ +P  G++AFSR+HPL+ W +T+LMCF GS ++N  +GEP ++  K H+ ++ A++ WY++NY PFD++++   F+PV +VIS+ KE+ R K VH G+ V A+ +PD++L+ + +G+ KG G  +         G    + N LL P+F  K  +A A++F +E++  +    + I    VIF IYFR+SS+L+GI DPFLPFE L C +F GG+ + L+ +KE+       K ++ +
Sbjct:    1 MDPQTFMNIATTVSKLKMWPYFDVCHYILMALAVREDSPQTGSQAFSRKHPLSCWVSTMLMCFGGSILANLMLGEPCIVAFKRHDMVLTATVVWYIINYSPFDILYRAAKFLPVRVVISVLKEVLRAKKVHQGVVVTAQLYPDAYLLMVIIGVVKGSGSYVIKNFERLVRGLWIPTTNELLQPSFTTKACIAAALIFVLERMNYLTAPHAVIHFGIVIFFIYFRLSSLLLGIHDPFLPFENLFCAVFMGGMWDALRRVKEEVKENGTTKDSKQD 274

[Close]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
Match: A0A1S3IL35 (trimeric intracellular cation channel type 1B.1 isoform X3 OS=Lingula unguis OX=7574 GN=LOC106165051 PE=4 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 5.579e-71
Identity = 106/274 (38.69%), Postives = 178/274 (64.96%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAP--GNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEAN 866
            MD +    +A  + +L+M+PYF++CHY++++L +R+ +P  G++AFSR+HPL+ W +T+LMCF GS ++N  +GEP ++  K H+ ++ A++ WY++NY PFD++++   F+PV +VIS+ KE+ R K VH G+ V A+ +PD++L+ + +G+ KG G            G    + N +L PTF  K  +A A++F +E++  +    + I    VIF IYFR+SS+L+GI DPFLPFE L C +F GG+ + L+ +KE+       K ++ +
Sbjct:    1 MDPQTFMNIATTVSKLKMWPYFDVCHYILMALAVREDSPQTGSQAFSRKHPLSCWVSTMLMCFGGSILANLMLGEPCIVAFKRHDMVLTATVVWYIINYSPFDILYRAAKFLPVRVVISVLKEVLRAKKVHQGVVVTAQLYPDAYLLMVIIGVVKGGGAAFMRSFERMVRGVWIPTVNEILLPTFTTKACIAAALIFVLERMNYLTAPHAVIHFGIVIFFIYFRLSSLLLGIHDPFLPFENLFCAVFMGGMWDALRRVKEEVKENGTTKDSKQD 274

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
Match: A0A1I8J9J2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007434g1 PE=4 SV=1)

HSP 1 Score: 226.868 bits (577), Expect = 5.060e-68
Identity = 102/250 (40.80%), Postives = 166/250 (66.40%), Query Frame = 3

Query:   75 VAKYLYQLEMFPYFNICHYLIISLHMRQI---APGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKE 815
            V+K L ++ M+P+F+  HY+++   +++    + G  AFSR+HP A W A++LMCF+GS + N  IGEPLV P K+H +++ A+  WY++NYFPFDL +K+  F PV+LV+ + KE++RT+ ++ G+ VA K +P+++L+ +++G+ KG G            G    + N  L P+F  K S+ +++ F +EK+  VP     IFL A++FL+YF++SS+++GI DPFLPFE + C +F GGL + LK 
Sbjct:   12 VSKTLQRVNMYPFFDAAHYILMCSIVKEDTAQSAGTSAFSRRHPFACWLASMLMCFSGSILGNLLIGEPLVTPFKHHRDILLATAIWYVINYFPFDLAYKVAKFAPVHLVVCIVKEVHRTRKIYDGVGVAYKLYPNAYLIVIAIGVFKGSGYLEMRLFERLIRGIWIPASNEFLQPSFATKASVFISLAFLLEKIGNVPSTHENIFLGAIMFLVYFKLSSMIIGIHDPFLPFENIFCSLFLGGLADALKR 261

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
Match: R7TM38 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_21604 PE=4 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 1.158e-67
Identity = 109/272 (40.07%), Postives = 170/272 (62.50%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQ-----IAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEM--KEKQAAEKN 845
            MD +    +A  + +L M+PYF+I HY+++S+ +R+        G   FSR+HP + W AT+LMCFAGS ++N  IGEPL+ P K H+ ++ A+  WY++NY PFD+++K+C F+P  LVIS  KE+ R   VH  +  A K +P S+L+ +++G+ KG G            G    S N +L P+FN KG LA +I+F +E+   +    + IF   VIF +YF++SS+L+GI D F+PFE L C +F GG+ + LK++  + ++ AE+N
Sbjct:    1 MDPQTFLDIATVVTKLRMYPYFDIAHYILMSMSVREDNHPPSTSGTHLFSRKHPFSCWIATMLMCFAGSIVANLLIGEPLITPFKDHQAVMTATAVWYVINYSPFDVIYKLCRFLPFKLVISCMKEVQRVHKVHHAVVFAMKNYPGSYLIIVTMGVLKGAGYTFMRTFERLLRGVWIPSSNEILQPSFNTKGCLAASILFILERKGLIDAPHAVIFFGVVIFFVYFKLSSLLLGIHDLFVPFENLFCAVFMGGIWDALKQVLSRGEKKAEEN 272

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
Match: A0A1S3IK28 (trimeric intracellular cation channel type 1B.1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106165051 PE=4 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 2.078e-67
Identity = 102/274 (37.23%), Postives = 174/274 (63.50%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAP--GNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEAN 866
            MD +    +A  + +L+M+PYF++CHY++++L +R+ +P  G++AFSR+HPL+ W +T+LMCF GS ++N  +GEP ++  K H+ ++ A++ WYL+NY P D+ +K    +P+ +V  LA E+ R K VH G+A+ AK  P+++L+ + + +++G G  +         G    + N LL P+F  K  +A A++F +E++  +    + I    VIF IYFR+SS+L+GI DPFLPFE L C +F GG+ + L+ +KE+       K ++ +
Sbjct:    1 MDPQTFMNIATTVSKLKMWPYFDVCHYILMALAVREDSPQTGSQAFSRKHPLSCWVSTMLMCFGGSILANLMLGEPCIVAFKRHDMVLTATVVWYLINYSPMDICYKTMRLLPLRVVAFLAVEIRRAKQVHDGVAITAKLHPNAYLLMIIIAVSRGSGSYVIKNFERLVRGLWIPTTNELLQPSFTTKACIAAALIFVLERMNYLTAPHAVIHFGIVIFFIYFRLSSLLLGIHDPFLPFENLFCAVFMGGMWDALRRVKEEVKENGTTKDSKQD 274

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Cavefish
Match: TMEM38B (transmembrane protein 38B [Source:NCBI gene;Acc:103038263])

HSP 1 Score: 136.346 bits (342), Expect = 1.367e-36
Identity = 76/237 (32.07%), Postives = 129/237 (54.43%), Query Frame = 3

Query:   75 VAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIF 785
            +A+ L  L MFPYF+  HY++  + +R+  PG    SR+ P A W +++L CF G+ +S   + E  V PL    N++ ASL WYL+ Y P D V+   + +PV LV++  KE+ RT  V  G+A A K++ D   V ++VG AKG G  +         G  +   N LL  ++  K +L  A++F +++ + +PL +  + L   +F++  +   +L+G      PF+++   +F
Sbjct:   12 LAEGLAGLPMFPYFDTAHYIVSVMALRE-QPGALEVSRRSPFACWFSSMLYCFGGAILSGIILAEAPVAPLANSTNVLLASLMWYLVFYCPLDAVYSCAAVLPVRLVLTGMKEVTRTWKVLSGVAQARKKYEDGLFVMIAVGWAKGAGGGLISNFEQLVRGIWKPETNELLKMSYPTKVTLIGAVLFSLQQCRYLPLQTPDLMLIYTVFIVVNKTRMMLMGSSSS--PFDSVESALF 245

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Cavefish
Match: tmem38a (transmembrane protein 38A [Source:NCBI gene;Acc:103041894])

HSP 1 Score: 108.227 bits (269), Expect = 3.221e-26
Identity = 69/256 (26.95%), Postives = 128/256 (50.00%), Query Frame = 3

Query:   48 IMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIH---ASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIK----DPFLPFETLICGIFFGG 794
            ++D      +A+Y  ++ MFP F++ +Y++  L+++   PG+   SR+ P+ASW   +L CF    +++  +G     P+ Y  N  H   AS  WYL+ + PF+L +K  +F+P+ LV+   KE+ RT+ +  G+  A   +   + + +  G  KG G  +         G      N +L+ +F  K SL  AI+F +++   +P+  S +     IF ++   S +++  +     PF   E+ +C + FG 
Sbjct:    3 VLDILNLGEIAQYFSKMAMFPVFDVAYYIVSILYLKY-EPGSVEVSRKSPVASWLCAMLYCFGSYILADIMLGHS---PIDYFHNNSHILLASAVWYLIFFCPFNLFYKCVAFLPIKLVLVAMKEVVRTRKIAAGVHHAHHAYHHGWFIMVITGYVKGSGVALMSNFEQLLRGVWRPETNEILSMSFPTKASLYGAILFTLQESHWLPVSKSTLI---CIFTLFMATSKVIMTARHSHGSPFALIESWVCHLLFGS 251

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Cavefish
Match: tmem38a (transmembrane protein 38A [Source:NCBI gene;Acc:103041894])

HSP 1 Score: 107.457 bits (267), Expect = 3.409e-26
Identity = 69/256 (26.95%), Postives = 128/256 (50.00%), Query Frame = 3

Query:   48 IMDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIH---ASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIK----DPFLPFETLICGIFFGG 794
            ++D      +A+Y  ++ MFP F++ +Y++  L+++   PG+   SR+ P+ASW   +L CF    +++  +G     P+ Y  N  H   AS  WYL+ + PF+L +K  +F+P+ LV+   KE+ RT+ +  G+  A   +   + + +  G  KG G  +         G      N +L+ +F  K SL  AI+F +++   +P+  S +     IF ++   S +++  +     PF   E+ +C + FG 
Sbjct:    3 VLDILNLGEIAQYFSKMAMFPVFDVAYYIVSILYLKY-EPGSVEVSRKSPVASWLCAMLYCFGSYILADIMLGHS---PIDYFHNNSHILLASAVWYLIFFCPFNLFYKCVAFLPIKLVLVAMKEVVRTRKIAAGVHHAHHAYHHGWFIMVITGYVKGSGVALMSNFEQLLRGVWRPETNEILSMSFPTKASLYGAILFTLQESHWLPVSKSTLI---CIFTLFMATSKVIMTARHSHGSPFALIESWVCHLLFGS 251

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Sea Lamprey
Match: tmem38a (transmembrane protein 38A [Source:NCBI gene;Acc:393874])

HSP 1 Score: 93.5893 bits (231), Expect = 1.059e-22
Identity = 52/156 (33.33%), Postives = 85/156 (54.49%), Query Frame = 3

Query:  327 YLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVS-SILVGIKDPFLPFETLICGIFFG 791
            Y++ YFP DL +++CS +PV L +   KE+ R + +  G+A A   +   ++V ++VGIAKG G  +   +     G  + + N LLN +F  K +L  A++F +E    +PL    + L   IFL+  +V+ + +     PF P ET +CG  FG
Sbjct:    1 YMVFYFPKDLYYRLCSLLPVKLFVVAGKEVTRVRKIAAGVAHAHHVYKRGYVVMVAVGIAKGAGSGLLANLEQLLRGVWKPNTNELLNMSFPTKATLLGAVLFTVEAAGWLPLSEEFLILIVTIFLVTTKVTLTAMHSHASPFDPIETPLCGFLFG 156

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Nematostella
Match: EDO31306 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYB0])

HSP 1 Score: 127.487 bits (319), Expect = 3.314e-34
Identity = 73/249 (29.32%), Postives = 125/249 (50.20%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAE 839
            Q+ MFP     H+ I+SL +R        F++ +PLA W + ++  FAGSF+ +FF+G P+V+PLK    +   +  WYL+ Y PFD+  K     P +L + + KE +R K +  G+++  + +P   LV + VGI KG G  +  P+A    G  + + +  L P+F  K S+  +I++ +     + + +  +     +     +VS  ++  +DPFL  E  +    FG   ET      K+  E
Sbjct:   17 QIPMFPVLQCVHFTIVSLKLRM--KLGTGFAQSNPLACWISAVISNFAGSFLISFFLGLPMVLPLKDVRAVAAMTTIWYLVFYCPFDIFNKFFMLQPAWLSLVVLKEAHRAKAILGGVSMGLEHYPTDLLVVVLVGIFKGAGALLVQPVAAVVQGSLDVTSHEALKPSFTTKASIVASILYTLVLKGIISISTECLCFGVFLVFALIKVSLHVMDAQDPFLHVEKALSPFCFGSPKETASTSDSKKKKE 263

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Medaka
Match: TMEM38B (transmembrane protein 38B [Source:NCBI gene;Acc:101173876])

HSP 1 Score: 141.739 bits (356), Expect = 1.080e-38
Identity = 90/321 (28.04%), Postives = 155/321 (48.29%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVG-IKDPFLPFETLICGIFFGG---LMETLKEMKE----KQAAEKNKKYTEANNLPPKCADGQGXXXXXXXXXXXXSFVDKDVETETDYHENSK 989
            M+  Y D ++  L  L MFPYF++ HY++  + +R+  PG    SR  PLA W +++L CF G+ +S   + EP V PL     ++ AS+ WYL+ Y P D+V+   + +P+ LV+S  KE+ RT  V  G+  A +++ DS LV +++G A+G G  +         G  +   N LL  ++  K +L  A++F +++   +P+    + L   IF++  +   +L G    PF   E+++    F G         E KE       A++  K   ++  P    +G+             S   K+  T +D  ++ K
Sbjct:    1 MELLYLDELSHGLANLSMFPYFDMAHYIVSVMALRE-QPGALEVSRASPLACWFSSMLYCFGGAVLSGIMLAEPPVAPLSNGTGVLLASIVWYLIFYCPKDVVYSSAALLPLRLVLSGMKEVTRTWKVLGGVTQARQKYKDSLLVMIAIGWARGAGGGLISNFEQLVRGVWKPETNELLKMSYPTKITLIGAVLFTLQQTHYLPVQKHHLMLVYTIFIVVNKSRIMLTGSSSSPFATIESVLYKTLFAGHSPYSALTGEAKEACINNDNAKREAKENGSSRSPSAAVEGRS-----------SSLRAKEESTSSDTKDSKK 309

[Close]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Medaka
Match: TMEM38B (transmembrane protein 38B [Source:NCBI gene;Acc:101173876])

HSP 1 Score: 141.354 bits (355), Expect = 1.162e-37
Identity = 90/321 (28.04%), Postives = 155/321 (48.29%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVG-IKDPFLPFETLICGIFFGG---LMETLKEMKE----KQAAEKNKKYTEANNLPPKCADGQGXXXXXXXXXXXXSFVDKDVETETDYHENSK 989
            M+  Y D ++  L  L MFPYF++ HY++  + +R+  PG    SR  PLA W +++L CF G+ +S   + EP V PL     ++ AS+ WYL+ Y P D+V+   + +P+ LV+S  KE+ RT  V  G+  A +++ DS LV +++G A+G G  +         G  +   N LL  ++  K +L  A++F +++   +P+    + L   IF++  +   +L G    PF   E+++    F G         E KE       A++  K   ++  P    +G+             S   K+  T +D  ++ K
Sbjct:   98 MELLYLDELSHGLANLSMFPYFDMAHYIVSVMALRE-QPGALEVSRASPLACWFSSMLYCFGGAVLSGIMLAEPPVAPLSNGTGVLLASIVWYLIFYCPKDVVYSSAALLPLRLVLSGMKEVTRTWKVLGGVTQARQKYKDSLLVMIAIGWARGAGGGLISNFEQLVRGVWKPETNELLKMSYPTKITLIGAVLFTLQQTHYLPVQKHHLMLVYTIFIVVNKSRIMLTGSSSSPFATIESVLYKTLFAGHSPYSALTGEAKEACINNDNAKREAKENGSSRSPSAAVEGRS-----------SSLRAKEESTSSDTKDSKK 406

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Medaka
Match: TMEM38B (transmembrane protein 38B [Source:NCBI gene;Acc:101173876])

HSP 1 Score: 132.88 bits (333), Expect = 1.040e-34
Identity = 71/219 (32.42%), Postives = 121/219 (55.25%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLI 707
            M+  Y D ++  L  L MFPYF++ HY++  + +R+  PG    SR  PLA W +++L CF G+ +S   + EP V PL     ++ AS+ WYL+ Y P D+V+   + +P+ LV+S  KE+ RT  V  G+  A +++ DS LV +++G A+G G  +         G  +   N LL  ++  K +L  A++F +++   +P+    + L   IF++
Sbjct:   98 MELLYLDELSHGLANLSMFPYFDMAHYIVSVMALRE-QPGALEVSRASPLACWFSSMLYCFGGAVLSGIMLAEPPVAPLSNGTGVLLASIVWYLIFYCPKDVVYSSAALLPLRLVLSGMKEVTRTWKVLGGVTQARQKYKDSLLVMIAIGWARGAGGGLISNFEQLVRGVWKPETNELLKMSYPTKITLIGAVLFTLQQTHYLPVQKHHLMLVYTIFIV 315

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Medaka
Match: tmem38a (transmembrane protein 38A [Source:NCBI gene;Acc:101165047])

HSP 1 Score: 110.923 bits (276), Expect = 1.916e-27
Identity = 69/240 (28.75%), Postives = 123/240 (51.25%), Query Frame = 3

Query:   78 AKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVS-SILVGIKDPFLPFETLICGIFFGG 794
            A+   ++ MFP F++ +Y++  L+++   PG+   SR+ P+ASW   +L CF    +++  +G   +   +++ +++ AS  WYL+ Y P +L +K  +F+PV LV+   KE+ RT+ +  G+  A   +   F + + VG  KG G  +         G      N +LN +F  K SL  AI+F M++   +P+  S + L   +F+   +V  +       PF   E+ IC + FG 
Sbjct:   14 AQAFSKMGMFPVFDLAYYIVSILYLKY-EPGSVEVSRRSPVASWLCAMLYCFGSYILADILLGSSPIDYFQHNSHILLASAVWYLIFYCPLNLFYKCVAFLPVKLVLVALKEVVRTRKIAAGVHHAHHAYHHGFFIMVIVGYVKGSGVALISNFEQLLRGVWRPETNEILNMSFPTKASLYGAILFTMQEAHWLPVSKSTLILVFTLFMATIKVVMTARHSHGSPFTLIESWICHLLFGS 252

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST
Match: SMESG000016165.1 (SMESG000016165.1)

HSP 1 Score: 620.928 bits (1600), Expect = 0.000e+0
Identity = 315/315 (100.00%), Postives = 315/315 (100.00%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANNLPPKCADGQGXXXXXXXXXXXXSFVDKDVETETDYHENSKKE 995
            MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANNLPPKCADGQGDIEDIIDTENDESFVDKDVETETDYHENSKKE
Sbjct:    1 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANNLPPKCADGQGDIEDIIDTENDESFVDKDVETETDYHENSKKE 315

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BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST
Match: SMESG000018720.1 (SMESG000018720.1)

HSP 1 Score: 216.853 bits (551), Expect = 1.256e-67
Identity = 100/263 (38.02%), Postives = 171/263 (65.02%), Query Frame = 3

Query:   51 MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAP--GNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQA 833
            MD      +A  + + ++FP+FN C+Y+++S+ +R+  P  GN  FSR+HP ASW AT++MCFAG+ ++ F +G+ ++  L+  ++++ A+ CWY++NY PFD+ +K+   +PV L++ + KE+ RTK ++ G+ +A+ + P + L+WL +G+ KG G      +     G    + N  L P+F  K SL+V+++F +  LQK+ +GS+  FL A++FLIYFR+  +L GI DP+ P E ++CGIFFGGL++  +    K +
Sbjct:    1 MDQSIIQDIANSVVKYKLFPFFNGCNYILMSMAVREDTPQSGNILFSRRHPFASWFATMIMCFAGNILAAFLLGDSILSTLEDFKDILLATACWYIVNYSPFDIFYKLNRLMPVRLLLCILKEIQRTKKIYHGVHMASSKHPRNILLWLIIGMVKGSGYSQLKILERLIRGVWLPASNEFLKPSFTTKASLSVSLLFVLVHLQKIAIGSNLDFLIAMVFLIYFRIIILLFGIHDPYAPLENIVCGIFFGGLVDAARNAWGKSS 263

[Close]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST
Match: SMESG000018720.1 (SMESG000018720.1)

HSP 1 Score: 194.897 bits (494), Expect = 1.780e-59
Identity = 92/239 (38.49%), Postives = 154/239 (64.44%), Query Frame = 3

Query:  138 ISLHMRQIAP--GNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNK 848
            +S+ +R+  P  GN  FSR+HP ASW AT++MCFAG+ ++ F +G+ ++  L+  ++++ A+ CWY++NY PFD+ +K+   +PV L++ + KE+ RTK ++ G+ +A+ + P + L+WL +G+ KG G      +     G    + N  L P+F  K SL+V+++F +  LQK+ +GS+  FL A++FLIYFR+  +L GI DP+ P E ++CGIFFGGL++  +    K +    K
Sbjct:    1 MSMAVREDTPQSGNILFSRRHPFASWFATMIMCFAGNILAAFLLGDSILSTLEDFKDILLATACWYIVNYSPFDIFYKLNRLMPVRLLLCILKEIQRTKKIYHGVHMASSKHPRNILLWLIIGMVKGSGYSQLKILERLIRGVWLPASNEFLKPSFTTKASLSVSLLFVLVHLQKIAIGSNLDFLIAMVFLIYFRIIILLFGIHDPYAPLENIVCGIFFGGLVDAARNAWGKSSKTDLK 239

[Close]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST
Match: SMESG000007025.1 (SMESG000007025.1)

HSP 1 Score: 185.652 bits (470), Expect = 6.740e-56
Identity = 88/263 (33.46%), Postives = 150/263 (57.03%), Query Frame = 3

Query:   93 QLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKEMKEKQAAEKNKKYTEANNLPPK 881
            ++EMFP+ + CHY ++S+ +R+ AP    FS+ HP A W ATI M FAG+ IS+  +G+ L+ PL+   +++ A+LCWY++N+ P+D V+KIC  +P+ + I + KE  RT  +H GI  A K++ ++FLVW+ VG  +G G      +    +  Q ++ +    P    K  L+V+I+F  +      L   +++   +IFLIY R++ +L+ I DPF+P E   CG+ F   +E + ++ +      + K    N    +
Sbjct:    8 KIEMFPFIDACHYTLMSMAVREDAPQLNMFSKNHPFACWIATIFMSFAGNIISSTLLGDSLLDPLQDIRSILLATLCWYIINFSPYDFVYKICCIMPIRISICIIKEFQRTFKIHYGILSANKKYENAFLVWIIVGTMRGAGSSFMRTVIAILIHSQPSALSGFKIPA-TSKACLSVSILFTFQVFFGNSLSQEKVYTVGLIFLIYIRLTILLLSIHDPFIPIENFFCGLLFESPLEKIHKVYKTMLTSTDDKTITENTTSQR 269

[Close]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST
Match: SMESG000030409.1 (SMESG000030409.1)

HSP 1 Score: 172.94 bits (437), Expect = 4.055e-51
Identity = 93/263 (35.36%), Postives = 151/263 (57.41%), Query Frame = 3

Query:   69 DVVAKYLYQLEMFPYFNICHYLIISLHMRQI-APGNKAFSRQHPLASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPFDLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVGIAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKLQKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLMETLKE-MKEKQAAEKNKK 851
            D ++  LY L M PYFNI ++++ISL  +      N +F + HPLA++  T+++ FAGS I NF  G+ L++ L+    L HAS+ WYL++Y P D+ +K+C+ +P++ +I + KEL R K +  GI  A  RFP S+LVW+  G  KG G +  + IA   + G   + N LL P++  K S  ++  + M+ +         +F++AV+ L YFR+  I  G  +PF   E ++  + FGGL + + +   +K  A + KK
Sbjct:    3 DDLSYNLYSLNMHPYFNISNFILISLLTKDTFRKDNISFIKSHPLANYILTMILSFAGSIIINFLYGDSLILILQNPTGLFHASIIWYLIHYCPGDIAYKLCNILPIFTIICVMKELQRCKNIFSGIDEAVVRFPGSYLVWIVAGTMKGSGTNWIVGIASVVINGVNKANNELLAPSYVTKMSFLISCAYLMKGMFSNYFTVQILFMSAVLVLTYFRLLIIFSGASNPFRKIENILSFVLFGGLADQISQSFWQKSMATETKK 265

The following BLAST results are available for this feature:

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Celegans
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Zebrafish
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Xenopus
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Cavefish
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Sea Lamprey
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Yeast
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Nematostella
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Medaka
BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TMEM38B	2.178e-28	27.42	transmembrane protein 38B [Source:HGNC Symbol;Acc:...	[more]
TMEM38A	7.927e-28	28.09	transmembrane protein 38A [Source:HGNC Symbol;Acc:...	[more]
TMEM38B	6.043e-17	26.04	transmembrane protein 38B [Source:HGNC Symbol;Acc:...	[more]
TMEM38A	3.531e-16	34.26	transmembrane protein 38A [Source:HGNC Symbol;Acc:...	[more]
TMEM38B	4.368e-12	26.14	transmembrane protein 38B [Source:HGNC Symbol;Acc:...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
tric-1B.1	2.774e-58	35.36	Trimeric intracellular cation channel type 1B.1 [...	[more]
tric-1B.2	2.049e-56	32.86	Trimeric intracellular cation channel type 1B.2 [...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG4239	8.940e-61	38.43	gene:FBgn0030745 transcript:FBtr0074269	[more]
CG4239	8.940e-61	38.43	gene:FBgn0030745 transcript:FBtr0340314	[more]
CG4239	8.940e-61	38.43	gene:FBgn0030745 transcript:FBtr0074270	[more]
CG4239	8.940e-61	38.43	gene:FBgn0030745 transcript:FBtr0074268	[more]
CG33061	7.190e-14	22.96	gene:FBgn0053061 transcript:FBtr0113448	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
tmem38a	7.450e-27	28.02	transmembrane protein 38A [Source:NCBI gene;Acc:39...	[more]
CABZ01079427.1	8.691e-21	25.11	pep chromosome:GRCz11:21:566286:588858:-1 gene:ENS...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
tmem38b	1.949e-36	31.62	transmembrane protein 38B [Source:NCBI gene;Acc:54...	[more]
tmem38a	1.854e-24	27.31	transmembrane protein 38A [Source:NCBI gene;Acc:39...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tmem38a	2.003e-28	25.61	transmembrane protein 38A [Source:MGI Symbol;Acc:M...	[more]
Tmem38b	4.644e-28	27.80	transmembrane protein 38B [Source:MGI Symbol;Acc:M...	[more]
Tmem38a	2.816e-18	30.22	transmembrane protein 38A [Source:MGI Symbol;Acc:M...	[more]
Tmem38b	4.266e-14	28.57	transmembrane protein 38B [Source:MGI Symbol;Acc:M...	[more]
Tmem38a	3.000e-8	29.03	transmembrane protein 38A [Source:MGI Symbol;Acc:M...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9NA75\|T38B1_CAEEL	3.529e-57	35.36	Trimeric intracellular cation channel type 1B.1 OS...	[more]
sp\|Q9NA73\|T38B2_CAEEL	2.607e-55	32.86	Trimeric intracellular cation channel type 1B.2 OS...	[more]
sp\|Q3KQE5\|T38BA_XENLA	8.304e-36	30.16	Trimeric intracellular cation channel type B-A OS=...	[more]
sp\|Q28FA9\|TM38B_XENTR	1.033e-35	31.62	Trimeric intracellular cation channel type B OS=Xe...	[more]
sp\|Q6GN30\|T38BB_XENLA	6.607e-35	30.83	Trimeric intracellular cation channel type B-B OS=...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3IM38	7.666e-72	38.69	trimeric intracellular cation channel type 1B.1 is...	[more]
A0A1S3IL35	5.579e-71	38.69	trimeric intracellular cation channel type 1B.1 is...	[more]
A0A1I8J9J2	5.060e-68	40.80	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
R7TM38	1.158e-67	40.07	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A1S3IK28	2.078e-67	37.23	trimeric intracellular cation channel type 1B.1 is...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
TMEM38B	1.367e-36	32.07	transmembrane protein 38B [Source:NCBI gene;Acc:10...	[more]
tmem38a	3.221e-26	26.95	transmembrane protein 38A [Source:NCBI gene;Acc:10...	[more]
tmem38a	3.409e-26	26.95	transmembrane protein 38A [Source:NCBI gene;Acc:10...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
tmem38a	1.059e-22	33.33	transmembrane protein 38A [Source:NCBI gene;Acc:39...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO31306	3.314e-34	29.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
TMEM38B	1.080e-38	28.04	transmembrane protein 38B [Source:NCBI gene;Acc:10...	[more]
TMEM38B	1.162e-37	28.04	transmembrane protein 38B [Source:NCBI gene;Acc:10...	[more]
TMEM38B	1.040e-34	32.42	transmembrane protein 38B [Source:NCBI gene;Acc:10...	[more]
tmem38a	1.916e-27	28.75	transmembrane protein 38A [Source:NCBI gene;Acc:10...	[more]

BLAST of trimeric intracellular cation channel type 1B.1 isoform X1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000016165.1	0.000e+0	100.00	SMESG000016165.1	[more]
SMESG000018720.1	1.256e-67	38.02	SMESG000018720.1	[more]
SMESG000018720.1	1.780e-59	38.49	SMESG000018720.1	[more]
SMESG000007025.1	6.740e-56	33.46	SMESG000007025.1	[more]
SMESG000030409.1	4.055e-51	35.36	SMESG000030409.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30012938 ID=SMED30012938|Name=trimeric intracellular cation channel type 1B.1 isoform X1|organism=Schmidtea mediterranea sexual|type=transcript|length=1213bp
TCAAATTATTTCTTTATTAATACTTAATATTATTTAACCACTAAAGTATA
ATGGACGCTAAGTATGCTGATGTTGTGGCCAAGTATTTGTATCAACTTGA
AATGTTTCCATATTTCAATATTTGCCATTATTTAATAATTAGTCTTCATA
TGCGTCAAATCGCACCAGGGAATAAAGCATTTTCACGACAACATCCTCTT
GCAAGTTGGTCAGCGACAATTTTAATGTGTTTCGCTGGTAGTTTTATATC
AAATTTTTTTATTGGTGAACCATTAGTTATACCATTAAAGTATCATGAAA
ATTTAATTCACGCGTCCTTATGTTGGTATTTAATGAATTATTTCCCTTTT
GATCTCGTATTCAAAATATGCTCATTTGTGCCGGTTTATTTGGTAATCAG
TCTAGCAAAAGAGTTATATCGTACCAAAATGGTACACATAGGAATTGCAG
TAGCTGCAAAGCGGTTTCCAGATTCTTTTCTTGTCTGGCTATCCGTCGGT
ATTGCAAAAGGTTGCGGTGAAGATATATTTTTACCGATTGCCTATTCATG
CATGGGTGGTCAAGAAGCCAGCGGAAATTTCTTATTGAATCCGACCTTTA
ATGTCAAAGGCAGCCTTGCAGTAGCAATAATGTTTGGAATGGAAAAGTTG
CAAAAAGTTCCGCTGGGATCATCTCAGATATTTCTAGCTGCAGTCATATT
TCTCATTTATTTCAGGGTGTCATCGATTCTCGTTGGTATCAAAGATCCTT
TTCTTCCTTTTGAAACATTGATTTGTGGAATTTTTTTCGGTGGTCTAATG
GAAACATTGAAAGAAATGAAAGAGAAGCAAGCTGCAGAAAAGAATAAAAA
GTATACCGAAGCAAATAATCTACCTCCAAAATGTGCTGATGGTCAAGGAG
ACATCGAGGACATAATTGACACTGAGAACGATGAGAGTTTTGTTGACAAA
GATGTCGAAACTGAAACCGACTACCACGAGAACTCTAAGAAAGAATTGAT
CAATAATTACTATTTGATCGATATTACTCGCCAGTGATGTGCAGTATAAA
TTATTGGATTTTAATTTTTTTGTGGTGCACATCGAATTGTTTGTCTCAGC
GAGTAAATTCAATTTCTACAGCACCTTCTGTTTCAAGCATTAATGTTTGT
TGTTTTTTTTCAATTTATGGTGTTTTTAACTGCTCTGTTGTCATTTTGTG
TTTTACACTCGCA

protein sequence of SMED30012938-orf-1

>SMED30012938-orf-1 ID=SMED30012938-orf-1|Name=SMED30012938-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=329bp
MDAKYADVVAKYLYQLEMFPYFNICHYLIISLHMRQIAPGNKAFSRQHPL
ASWSATILMCFAGSFISNFFIGEPLVIPLKYHENLIHASLCWYLMNYFPF
DLVFKICSFVPVYLVISLAKELYRTKMVHIGIAVAAKRFPDSFLVWLSVG
IAKGCGEDIFLPIAYSCMGGQEASGNFLLNPTFNVKGSLAVAIMFGMEKL
QKVPLGSSQIFLAAVIFLIYFRVSSILVGIKDPFLPFETLICGIFFGGLM
ETLKEMKEKQAAEKNKKYTEANNLPPKCADGQGDIEDIIDTENDESFVDK
DVETETDYHENSKKELINNYYLIDITRQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0034220	ion transmembrane transport
GO:0098655	cation transmembrane transport
GO:0015672	monovalent inorganic cation transport
GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0071805	potassium ion transmembrane transport

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal
PLANA:0000418	head
PLANA:0002056	medial muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR007866	TRIC_channel

Vocabulary: **molecular function**
Term	Definition
GO:0005261	cation channel activity
GO:0005267	potassium channel activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Main menu

trimeric intracellular cation channel type 1B.1 isoform X1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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