Cytochrome P450 2K1-like protein

Query:    2 MILVVLFCITVYVFYKFYL-RKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAP-FQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            +++ +L C+TV V    +  RK+   LP    P       LP +GN L +++   +  L  + E+YGP+++I +G + ++VL  +D + ++L +Q   FSGR        + K  G++F + E     R F++  LRDFG GK+  E  +  E   ++  ++   G NI+ T  +S    N+IS  +    F+  D+  L +++ +  I +    ++    ++ +F      S+M        +  Q +    DFI   VE H +R    N  +D ID+FL+         + N  F    +V     LF+ G ET + TL + FLLL  HPE++ K+ +EI + IG  R P   D+  + Y +AV+ EI R+  V+P+S+A RV ++     FF+P  + ++P L +  RDPS +  P DF P+HFLNE G ++     VPF +GKR C GE LARME F+   + +Q F +  S   K +D
Sbjct:    7 LLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTP-------LPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTST--GQLYEMFS-----SVMKHLPGPQQQAFQLLQGLEDFIAKKVE-HNQRTLDPNSPRDFIDSFLIRMQ--EEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDID 472          

Query:  155 APFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVA-DVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDR-TTDFIGSIVEDHRKRFCPENESQDLIDAFLL--EQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLN 1507
             P   L  L   YG I+S  IG   ++VL+++  + ++L +Q   FS R        + K+ G++F      W  QR F+   LR FG GK   E  +  E + +  E++           ++S A  N+I      + F+  +     ++  +     +  +   L++N+ P   + P         F P + ++ I++  T F+  I++DH++    EN  QD ID +LL  E+ R N+ NS   SF +  +  +I +LF+AG +TT N+L W  L ++++P++Q K+ +EI + IG  R P++ DK  + Y +A + E+ R + V+PL+I H   EN  + G+ +P  +++ PNL++ HRDP++W+KP DFYP  FL++ G    K   +PFG+GKR C+GE LA+ME F++ VS +Q F+ +L ++SKK     LL G  G    P  H  N
Sbjct:  102 GPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLP---------FGPFKELRQIEKDITSFLKKIIKDHQESLDREN-PQDFIDMYLLHMEEERKNNSNS---SFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKK----PLLTGRFGLTLAP--HPFN 538          

Query:   59 RKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAP-FQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            RK+   LP    P       LP +GN L +++   +  L  + E+YGP+++I +G + ++VL  +D + ++L +Q   FSGR        L K  G+ F + E     R F++  LR FG GK+  E  +  E   ++  ++  +G NI+ T  +S    N+IS  +    F+  D+  L +++ +     +        +   +++ F   S+M        +  + +    DFI   VE H +R    N  +D ID+FL+         + N  F    +V     LF AG ET + TL + FLLL  HPE++ K+ +EI + IG  R P   D+  + Y +AV+ EI R+  +LP+ +AHRV ++     FF+P  + +FP L +  RDP  +  P DF P+HFL++ G ++     VPF +GKR C GE LARME F+   + +Q F        K +D
Sbjct:   27 RKSRGKLPPGPTP-------LPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMM-----LGSFQFTATSTGQLYEMFS--SVMKHLPGPQQQAFKELQGLEDFIAKKVE-HNQRTLDPNSPRDFIDSFLIRMQ--EEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDID 472          

Query:   59 RKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLND----LREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            RK+   LP    P       LP +GN L +++   +++ D      E YGP+++I +G + ++VL  +D + ++L +Q   FSGR        + K  G+ F + E       F +  LRDFG GK+  E  +  E   +++ I+  +G NI+ T  +S    N+IS  +    F+  D+  L ++  +  I +    ++    ++ +F      S+M        +  + +    DFI   VE H +R    N  QD ID+FL+  H      + N  F    ++     LF+AG ET + TL + FLLL  HPE++ K+ +EI + IG  R P   D+  + Y +AV+ EI R+  V+P+S+A RV ++     FF+P  + +FP L +  RDPS +  P DF P+HFL++ G ++     VPF +GKR C GE LARME F+   + +Q F +  S   K +D
Sbjct:   27 RKSRGKLPPGPTP-------LPFIGNYLQLNT---EHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTST--GQLYEMFS-----SVMKHLPGPQQQAFKLLQGLEDFIAKKVE-HNQRTLDPNSPQDFIDSFLI--HMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDID 472          

Query:    8 LVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPF-QYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSL-VMNVFPIF-DWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFL--LEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNG 1465
            +V++ C++  + +  + +   S     L P P     LPI+GN+L +      +   +  + YGP++++  G   I+V + Y+ + ++L + G  FSGR  +  ++ + K  GI+  + + W   R F+L  LR+FG GK+  E+ V  E   +V+E++       + T ++  A  N+I   + ++ F+  D+N L ++K   +  R+ +   + V N FP+  D FP             ++++ +  T  +I   V++H+      N  +D ID FL  +EQ + N    +   F    +V  +++LF+AG ETT+ TL +  LLL  HPE+  K+++EI   IG  R P M D+  + Y  AV+ EI RYS ++P  + H V  +     + +P  + +   L +   D   +  P  F P HFL++NGN++     +PF  GKR C GE LARME F+ + + LQ F++   D+ K L+T  +  G
Sbjct:    5 VVLVLCLSFMLLFSLWRQ---SCRRRKLPPGPT---PLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTH---------NKVLKNVALTRSYIREKVKEHQASL-DVNNPRDFIDCFLIKMEQEKDN----QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAP--FQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWA-NVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREF----ENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPEN---ESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDES 1432
            +I+++L  +T+Y  Y+ Y ++       +  P P     LP+ GNLL++++ P  ++      +KYG +Y+  IG    I++N +D I ++     +T++ +    + T     + GI+  +   W   R F L  +RDFG GK   +  +  E++ +   +  K G   +  ++   A  N+++  +    F    EN  + + ++I S  +I     +  L MN+ PIF      SL    Y  P++  +  D T  F    +E HR R   E+   ES D ++ FL EQ R  S    + ++++ Q++ +  +L+ AG  TT NT++W    +  HPE+Q KI +E+ K IG  R  T  DK  L Y  A ++E  R   +LPL++ H    +  I+GF +P  + +   +     +  V+  PY F P+ F++ENG  +   EL PF +GKR C GE LARME F+ + +FL ++ I  S E 
Sbjct:    2 IIILLLTFLTIYFVYELYWKR------RNFPPGPCP---LPVFGNLLSIANPPPGYKAFERWTKKYGDVYTFWIGNTPHIMINTWDKIKETFIRDADTYTNKVVLPMVTLSRGGEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYRFMGPKENEYQELKHIIDSPAEIFGKLHI-FLAMNI-PIFAKLLPESL----YEGPIKTFR--DTTLAFFNKQIEAHRHRIDFEDLNSESTDFVETFLKEQKRRES-EGDSETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLITTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFIDENGKLKKVDELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIHPSKEG 470          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNV--SSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDL-AKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIF--DWFPRISLMLIYYFHPMRIIQTI-----DRTTDFIGSIVEDHRKRF-CPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDES 1432
            +IL+V      ++F++ Y ++ +  LP    PIP     LP +GN+L +  +   ++   +  +KYG +Y+  +G    +++++YD++  +    G+T+  ++     + +   + GI+  +   W+T R F L  LRDFG GK   +  +  E+E + K+   + G   + + +++ A  N+I+  I    FE + E     ++ + +    A         F ++   + P++  +L     P R +  +     D    F  + +E+HRK+      ES D  +A+L EQ +  +L  +   F++ Q+     +L+LAG  TT  T++WT   +  HP++  K+ +E  + +G  R  TM DK +L Y  AVL+E  R + ++P+++ H   ++  ING+ V   + +   +     D  ++  PY F P+ F++ENG      +L+PF +GKRQC GE LARME F+ + +F  ++ IS S + 
Sbjct:    2 IILLVFTAFLAFLFHELYWKRRN--LPPG--PIP-----LPFMGNILTMLLNKPGYECFRNCTKKYGDVYTFWMGKTPFVMISSYDLLKDTFVRDGDTYKDKYPQPLNQKIRGGNYGIVESNGHLWSTHRRFALTTLRDFGLGKDLMQEKILIEVEDIFKKFDAQLGLEQDVSVVMNNAIANVINQNIFGYRFEGDKEEDFKKLRELMEYQETA------FATFKVYVEAFIPKVGALL-----PGRSLNELLEEWRDNFYTFFDTQIENHRKKIDFDSQESLDYAEAYLKEQRKQEAL-GEFELFSNKQLSNTCLDLWLAGLSTTNTTVNWTICYVLNHPDVLQKMNEEFDQVVGSDRLVTMGDKNNLPYFNAVLNESQRCANIVPINLFHATTKDTVINGYPVKKGTGVIAQISTVMLDEKIFPDPYKFNPDRFIDENGKPIKIEQLIPFSIGKRQCPGEGLARMEMFLFLANFFNRYKISPSSKG 468          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQ-YLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDL---AKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIK-LKNGRNIETTKLVSFATVNMISD--FIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVEL---VPFGLGKRQCLGEALARMEEFIVVVSFLQKF 1408
            M + +L  +   +FY F+     S  P    P+P     LP +GN+        Q Y + L + YGP ++I I +   IVL +Y+ I  +   QG+TF+ R A+   + L      +GIL  D + W  QR  +L++LRDFG G+   E  V R + +M+ +++ + + +N++    +     N+I++  F    ++E++++   +V    + +  +     L+++ FP   W   + ++    +H   I   I     FI   V    K++  E+E ++ + A++ +  +     + N       +   + + +LAG ETT+N+L W    +  +PE+Q K+R EI   +G  R P+M+DK ++ Y QAV+ E+ R S ++P   +H+  E   I+G  VPA S++F  L++  R+ +V++ P  F P  +L  +G    K  L   +PF +GKR C+GE LARME F++  + +QK+
Sbjct:    1 MSVFILAFVIFIIFYVFHFYWKVSKYPK--GPLP-----LPFIGNIHQFPPDNVQKYFDVLSKTYGPCFTIWIPFP-AIVLTDYEHIKDAFVNQGDTFTYR-AHRSPETLLPVHDHTGILASDGDHWRLQRRTSLKILRDFGLGRNLMEEQVIRSVHEMLIQLENINDKKNVDVFWPIQLCVGNVINETLFGFHYKYEDSEKFKTFVKIVDKHLRHLQGKMPLLVSAFP---WLKHVPIVGDIGYH--NIKNNISSYHTFIEEEVATQVKKYDGESEPENFVHAYMQQMKQ-----TGNPGLDITNLCATVLDFWLAGMETTSNSLRWHLAFMMKYPEVQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPFLGSHQCKEETEIHGNRVPAGSLVFAQLWSVMRNDTVFEDPETFNPSRYLQSDGKTFDKAVLEKTIPFSIGKRNCVGEGLARMELFLIFSALIQKY 460          

Query:   17 LFCITVYVFYKFYLRKTSSALPSHLKPIP-VVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDS-GILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLK---NGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMN-VFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHR---KRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTM--NDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDE 1429
            L CIT+Y  Y+   ++    LP+   P+P +V+G +P   N+ NV    FQ     +++YG I+++ IG   ++++++   I K   +  ++FS RW N  T  + + S GI+  D   W  QR F L  LRDFG GK   E ++  E+  ++  ++     +G+ +     ++    N+I++ +    F N D + ++ +  + D     D +  VM  +   +  FP  S + I      R++   +   +F+ + +E HR   K    E E +DL  A+++E  +          F D Q+  L+ +LF AG ETT  TL W FLL+A + ++Q  ++ E+      I  P +    +  L Y QA ++EI R + +LP+++   V E+  I+G+      ++ P +     DP +++ P +F P  FL+E+ N +   E +PF +G+RQCLGE+LAR E ++V  + +Q F+  ++D+
Sbjct:   38 LTCITLYAIYELNYKR--RRLPN--GPVPWLVAGNMPSFINVNNVDVL-FQ---SWKQQYGGIFTVWIGPIPLVMVSDLPTIKKYFIQHADSFSNRWRNFVTDSIMEGSNGIVQIDGNKWREQRRFALHTLRDFGVGKPLMEQMITLEVTSLMNHMEKSCGLDGKELHLCPSIAVCVGNIINNMLFGLRF-NQDNSYMHRLHQLLD-----DQSHTVMQPIMGAYIAFPVTSKIPIINGEWNRLMGIKNELLEFLETQIEGHRMNWKDEMIEQEPEDLTYAYMIEVEKRKRNGEDVGFFDDQQLKMLLLDLFFAGMETTVTTLKWAFLLMAKNQKVQKNVQAELDS----IGQPMIEIQHRTRLPYVQATINEIQRIANILPINLLRTVAEDIEIDGYNFKKGDLIIPQISILMNDPEIFENPEEFNPSRFLDEDNNVKKIDEFLPFSIGRRQCLGESLARAELYLVFANLIQNFNFEVADD 501          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQ-YLNDLREKYGPIYSIQIGWKNI--IVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAK---DSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEI-KLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQD--IARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVEL---VPFGLGKRQCLGEALARMEEFIVVVSFLQKF 1408
            IL+V F +++ V+  ++  K S        P P     LP +GN+L + S   Q YL+DL + YGP +++   W  +  IVL +Y+ + ++   QG+ F  R A+   + L +   ++G+LF + + W  QR   L++LRDFG G+   E  V R + +M+ ++ ++ + +N++    +     N+I++ +    ++  D         + D  +  V      +M+ FP    FP I  +    +H  RI + I    +FI   V    K +  E+E ++ + A++ +  +     S N +     +   + + +LAG ETT+N+L W    +  +PEIQ K+R EI   +G  R P+M+DK ++ Y QAV+ E+ R S ++P+   H   ++  + G  +P  +++F  +++  ++  V+++   F P+ +L  +G    K  L   +PF +GKR C+GE LARME F++  + +QK+
Sbjct:    3 ILIVAFLVSITVYIAYFYWKVSKYPKG---PFP-----LPFIGNILQIPSENIQEYLDDLSKTYGPCFTL---WTPLPAIVLTDYEHVKEAFVTQGDAFIYR-ADRPPETLLQPHLNTGVLFSNGDNWRFQRRTALKILRDFGLGRNLMEEQVMRSVHEMLAQLERIADKKNVDMFWPIQLCVGNVINESLFSYHYKYEDSKKFETFVKVLDKHLKTVQGKTIFLMSAFPWLKHFPVIGEL---GYH--RIKKNIQSYQEFINDEVTSQIKHYDGESEPENFVHAYMQQMKQ-----SGNPNLDMNNLCASVIDFWLAGMETTSNSLRWHLAFMMKYPEIQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPILGTHTNRDDILLKGKKIPTGTLVFAQIWSVLKNDPVFEESSKFNPDRYLMADGKTINKSVLERTIPFSVGKRNCVGEGLARMELFLIFSALIQKY 460          

Query:   89 LKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGF-----GKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNS-------LNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSD 1426
            L+ +P    GLP++G LL + S       +L ++YG ++S ++G +  +V+++Y +I +  + +   F+GR    F + L    GI+    + W  QR F    LR FG      GKQ  +  +  E+ + +  +   +G+ ++ + ++S A  N+I   +M   F  +D         I++  R+  +++++  +  P    FP IS          +I Q       F   +++DH++ F P N  +DL+D +L E  +  +        + KNH   + Q+V++I +LF AG ET   TL W  + +  +P+   +++DE+ + +G  R PT+ D + L   ++ + E  R S+++PL+  H    +  +NG+ +PA S + P + + H DP++W+KP +F P  F++  G  +     +PFG+G+R CLG+ LARME F+   SF+  F I+L +
Sbjct:   50 LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTV--DYIPTMQCFPSISTA------KNKIAQNRAEMQRFYQDVIDDHKRSFDPNN-IRDLVDFYLCEIEKAKAEGTDAELFDGKNH---EEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493          

Query:   89 LKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGF-----GKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNS-------LNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSD 1426
            L+ +P    GLP++G LL + S       +L ++YG ++S ++G +  +V+++Y +I +  + +   F+GR    F + L    GI+    + W  QR F    LR FG      GKQ  +  +  E+ + +  +   +G+ ++ + ++S A  N+I   +M   F  +D         I++  R+  +++++  +  P    FP IS          +I Q       F   +++DH++ F P N  +DL+D +L E  +  +        + KNH   + Q+V++I +LF AG ET   TL W  + +  +P+   +++DE+ + +G  R PT+ D + L   ++ + E  R S+++PL+  H    +  +NG+ +PA S + P + + H DP++W+KP +F P  F++  G  +     +PFG+G+R CLG+ LARME F+   SF+  F I+L +
Sbjct:   50 LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTV--DYIPTMQCFPSISTA------KNKIAQNRAEMQRFYQDVIDDHKRSFDPNN-IRDLVDFYLCEIEKAKAEGTDAELFDGKNH---EEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493          

Query:   11 VVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLN----VSSAPFQYL------NDLREKYGPIYSIQIGWKNIIVLNNYDVINK-SLKEQGNTFSGRWANVFTK--DLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIM-KREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTT-DFIGSIVEDHRKRFC--PENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIR---WPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISL 1420
             ++F   + + +  Y   +S+  P +  P P     +P +GN L      S+   Q++       D R     +  +++G + ++V   ++++ +  L+E    F GR  N F +   +    GI   D + W   R F ++ +R+ G+G+   E+ +  E E+++ +++    + IE    ++ + +N++   I  KR     D  +  ++  +   +++ D+   ++  FP   W   ++     Y     +IQ ++     F    +E+HR++    P     DLI A+L E  +  S   ++ +F + Q+V  I + F+AG +TT+NT++   ++LA+ P++Q K+  +++  +       +P ++ +++ +Y  A + E+ R+  + P++   R L    + G+ +P ++ +  +L + H D   WK P +F PE F++  G        +PFG+G+R+CLG+ALAR   F  +V  +Q FS+ L
Sbjct:    3 ALIFLCAILIGFVIYSLISSARRPKNFPPGPRF---VPWLGNTLQFRKEASAVGGQHILFERWAKDFRSD---LVGLKLGREYVVVALGHEMVKEVQLQE---VFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFP---WLRHVAPDRTGY----NLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEM-KDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVL 475          

Query:    8 LVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSA--------------PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDS--GILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIK---LKNG---RNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMN-DKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSI 1414
            ++ +FC T+       +RK     P    P P      PIVG+ L VS                  QY+N     YG  Y ++IG   +++    D I++ +  +     GR   +F +    +S  G+L  D E W  QR F LR L++FGF +    ++V+ E   +++++K   LK+G     IE   L S   +N +   +  R +E     I  ++++  ++ +  D+      V  +F  FP +  +   +      +++      F+   +E HR  +   +E +DL+D++L  Q   +  N +   F+D  ++ +  ++FLAG ETT  +L + F+ L + PEIQ +   EI + +G  R P  + D+  L YC+A+  E  R   +    I HR + +  ++G+ +P D+++         +P  +  P  F P+ +L  +G+ +      PFG G+ +C+G+ L R   F+   + LQ F +
Sbjct:    5 VIWIFCATLLAILFGGVRK-----PKRFPPGPAW---YPIVGSALQVSQLRCRLGMFCKVIDVFARQYVN----PYG-FYGLKIGKDKVVIAYTNDAISEMMTNE--DIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDM------VGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQ---DEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLF-DGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:    8 LVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSA--------------PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDS--GILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIK---LKNG---RNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMN-DKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSI 1414
            ++ +FC T+       +RK     P    P P      PIVG+ L VS                  QY+N     YG  Y ++IG   +++    D I++ +  +     GR   +F +    +S  G+L  D E W  QR F LR L++FGF +    ++V+ E   +++++K   LK+G     IE   L S   +N +   +  R +E     I  ++++  ++ +  D+      V  +F  FP +  +   +      +++      F+   +E HR  +   +E +DL+D++L  Q   +  N +   F+D  ++ +  ++FLAG ETT  +L + F+ L + PEIQ +   EI + +G  R P  + D+  L YC+A+  E  R   +    I HR + +  ++G+ +P D+++         +P  +  P  F P+ +L  +G+ +      PFG G+ +C+G+ L R   F+   + LQ F +
Sbjct:    5 VIWIFCATLLAILFGGVRK-----PKRFPPGPAW---YPIVGSALQVSQLRCRLGMFCKVIDVFARQYVN----PYG-FYGLKIGKDKVVIAYTNDAISEMMTNE--DIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDM------VGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQ---DEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLF-DGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  128 VGNLLNV-SSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIAR-VADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSK-NHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            +GNLL +  SAPF+     R+ YG + ++ +G + ++VL  Y+ + ++L +Q + F+ R    F   + K  G+   + E W   R FTL  LRDFG G++  E  +  E   ++K  +    + ++ T   S    N+I   +  + F+  D+N L +++ I  + R ++     + N+FP         +M  +      I++ ++    FI + V++H +R    + S D ID FL+   RL     K +  F    ++  +  LF+AG ETT+ TL +  +LL  HP+IQ +++ EI + IG  R PTM D+KSL +  AV+ E+ RY  ++PLS+ H  +++ +  G+ +P D+++ P L++  RD   W+ P+ F PEHFL+ NGN++     +PF  GKR C+GE+LARME F+ +VS LQKFS S  +    +D
Sbjct:   40 IGNLLTLDKSAPFKSFMKWRKTYGSVMTVHLGPQRMVVLVGYETVKEALVDQADDFAPRAPIPFMNRIVKGYGLAISNGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLRFLSSPWGQLYNIFP--------QVMESFSSRHHAILKDVENIRTFIRNKVKEHEQRLDFSDPS-DFIDCFLI---RLTQEKDKLDTEFHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGHWETPWTFNPEHFLDSNGNFKKNPAFMPFSAGKRVCVGESLARMEIFLFIVSLLQKFSFSSPNGPDSID 469          

Query:   92 KPIPVVSGGLPIVGNLLNV-SSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLE-QHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESK 1435
            K +P     LP +GN+ N+ +S P   L  + + YG I+S+++G  N +V+N Y ++ K L +QGN+F  R  N  T+ ++K  G+ F +   W   R FTL  L+ FG GK+  E ++  E + + + I   NG       +++    N+I   +  R FE  D+  L ++  I    ++   V   +   FP + D  P     L   FH +R          FI   V+ HR  + P +  +D ID +L E + + + L +    F D  +   + +LF+AG ETT+ TL W F+ +  +PEIQ K++ EI K +G  R P+M+D+  + Y  AV+ EI R   V+PLS+     E+  + G+F+P  + + PNL +   D + WK  + F P++FLN  G ++     +PF LGKR C GE+LARME F+   SFLQ FS+S  DE++
Sbjct:   43 KNLPPGPTPLPFIGNVFNLDTSQPHIDLTKMSDHYGNIFSLRLGSLNTVVVNTYSMVKKVLNDQGNSFMYRPVNDITERISKCQGLTFNNGYSWKQHRRFTLSTLKFFGVGKRSLEFIIMEEYKFLHQSIMDTNGLPFNPHYIINNGVSNIICSMVFGRRFEYTDQRFLNMLSLISKALKLQTSVFIQLYAAFPRLMDLLPGPHKELFSCFHQVRA---------FIKEEVDKHRADWDPSS-PRDFIDCYLTEIEKKKDDLEA---GFHDEGLQYAVLDLFVAGTETTSTTLLWAFVYMMKYPEIQEKVQAEIDKVVGRYRRPSMDDRPCMPYTDAVIHEIQRMGNVVPLSVPRMTNEDTILEGYFIPKGTQIIPNLTSVLFDQTKWKTQHSFDPQNFLNAQGKFEKPEAFIPFSLGKRSCPGESLARMELFLFFTSFLQSFSLSAPDETQ 481          

Query:  128 VGNLLNV-SSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIAR-VADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSK-NHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            +GNLL +  SAPF+     R+ YG + ++ +G + ++VL  Y+ + ++L +Q + F+ R    F   + K  G+   + E W   R FTL  LRDFG G++  E  +  E   ++K  +    + ++ T   S    N+I   +  + F+  D+N L +++ I  + R ++     + N+FP         +M  +      I++ ++    FI + V++H +R    + S D ID FL+   RL     K +  F    ++  +  LF+AG ETT+ TL +  +LL  HP+IQ +++ EI + IG  R PTM D+KSL +  AV+ E+ RY  ++PLS+ H  +++ +  G+ +P D+++ P L++  RD   W+ P+ F PEHFL+ NGN++     +PF  GKR C+GE+LA ME F+  VS LQKF+ S  +    +D
Sbjct:   40 IGNLLTLDKSAPFKSFMKWRKTYGSVMTVHLGPQRMVVLVGYETVKEALVDQADDFAPRAPIPFMNRIVKGYGLAISNGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLRFLSSPWGQLYNIFP--------QVMESFSSRHHAILKDVENIRTFIRNKVKEHEQRLDFSDPS-DFIDCFLI---RLTQEKDKLDTEFHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGQWETPWTFNPEHFLDSNGNFKKNPAFMPFSAGKRSCVGESLASMELFLFTVSLLQKFTFSSPNGPDGID 469          

Query:   11 VVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVS--GGL---PIV-----------GNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKE----IKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVA---DVNS--LVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRT----TDFIGSIVEDHRKRFCPENESQDLIDAFLLEQ-HRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            ++ F +  YV  ++   +T + +P   KP P+V   GG    P +             +++   +P   L ++ + YG I+SI +G + ++VL  YD +  ++     TFS R        + K  GI+F      W T R F    LR FGFG+   E  ++  +  +  E    I+      I+ T L+S A  N+IS   + + F + D+      ++++D+        VN+  L++NVFP   W          Y+ P  + + + R     T F+  I+  HR    PEN  +D ID +L+E   +    +S+ + F++  +  +I +LF+AG +TT N++ W+ L ++++P++Q K++ EI   +G  R P++ DK SL Y +A + E+ R + V+PLSI H   E     GF +P  +++ PNL++ HRDP+VW+ P DF P  FL++ G    K   +PFGLG+R C+GE LA+ME F++  S +Q F+
Sbjct:   21 LIAFVLVFYVLQEYQWHQTYANIPPGPKPWPIVGNFGGFLVPPFILKRFVKNSKEFAKVVSNPLSPQAGLIEMSKLYGNIFSIFVGPQLMVVLTGYDAVRDAMLNHTETFSDRPHIPLVTIITKRKGIVFAPYGPLWRTNRRFCHSTLRSFGFGRMSLEPCIHEGLAIIKTELQSLIETAGPSGIDLTPLISNAVSNIISLMSLGQRFHHEDKEF----RNMRDLMSHGLEISVNTSILLVNVFP---WL---------YYLPFGVFKELRRAELDITAFLKRIIARHRATLDPEN-PRDFIDMYLVEMLAKQKEGSSEENLFSEDDLFYIIGDLFIAGTDTTTNSMLWSILYMSLYPDVQEKVQKEIDAVVGSERVPSLTDKSSLPYTEATIMEVIRMTVVVPLSIPHMASETTEFRGFTIPKGTVIIPNLWSVHRDPTVWENPDDFNPSRFLDDQGKILRKDCFIPFGLGRRVCMGEQLAKMELFLMFTSLMQTFT 501          

Query:  119 LPIVGNLLNVS-SAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWF-PRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQ--KFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTL 1504
            LP+VGNLL +  + PF     L + YG ++ + +G +  +VL  Y  + ++L      F  R        +  + GILF + E W   R F L  LRDFG GK+ +E  +  EI  +  E     G+  +TT+ V++A  N+IS  +    FE  D     ++    +  RV    S+ M ++ IF W  P +    I   +   IIQ+  + T  I +++E         N+ +  +D+FL+ +        K+  F +  ++  ++ LF+AG +TT  TL W  +L+A +P IQ ++++EI + IG  R P + D+K L Y  AV+ EI R + ++PLS+ HR   + + NG+F+   + + P L +  +D S W+KP  FYPEHFL+E G +  +   +PF  G+R CLGE+LARME F+   S LQ  +F+        +LD    L G  G    P+ H L
Sbjct:   51 LPLVGNLLTLDLTRPFDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVG--GSISMWLYDIFPWLGPFLKNKRIIVEN---IIQSRVQMTKLITALLET-----LNPNDPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELD----LKGIVGITLNPSPHKL 501          

Query:   23 CITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNL--LNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVM-NVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            CI ++  + F   K S   P   KP       LP++GNL  +N+   P+    +L +KYGP++S+Q+G K  +VL   D +  +L    + FSGR     ++  +K +GI+F + E W   R FTL  LRDFG GK+  E+ +  E + +V+  K   G+  + T +++ A  N+I   ++   F+  D   L +IKS+ D  R      +V+ N FP I  W P             RI  +     +F+  I    RK     N+ +DL+DAFL++Q    S ++K   F D  +  LI  LF AG ETT+ TL W  LL+  +PEIQ K++DEI + +G    P    +K + Y  AV+ EI R++ ++P  + H    + +  G+F+P  + +FP L +  RD + +KKP +FYPEHFL+  GN+      +PF  GKR C GE LA+ME F+     LQ F+
Sbjct:   13 CIFLFKVF-FGGEKESQNFPPGPKP-------LPLIGNLHIMNMKK-PYLTFMELAKKYGPVFSVQLGTKKTVVLCGTDAVKDALINYADEFSGRPKTPLSEQASKGNGIIFANGENWKVMRRFTLSTLRDFGMGKKTIEDRISEESDCLVETFKSHKGKPFDNTLILNAAVANIIVHILLNHRFDYQDPTFLKLIKSVNDNVRNGARPIIVLYNAFPSIIRWIPGTH---------KRIFASSQNFFNFLKEIFM-KRKDQLDVNDQRDLVDAFLVKQQEEKSSSTK--FFHDENLKVLIGNLFGAGMETTSTTLRWGILLMMKYPEIQKKVQDEIDRVMGSTE-PRPEHRKQMPYTDAVIHEIQRFADLVPNGVPHATTTDVTFRGYFLPKGTQVFPLLTSVLRDKAYFKKPDEFYPEHFLDSEGNFLKNEAFLPFSAGKRICAGETLAKMELFLFFTKLLQNFT 457          

Query:   23 CITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVS-SAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVM--NVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            CI ++ F+ +   K S   P   KP       LP++GNL  ++   P+    +L EKYGP++S+ +G    +VL   D +  +L    + FSGR      +   K +GI+F D E W   R FT+  LRDFG GK+  E+ +  E   +V+  K   G+  + T +++ A  N+I   ++K  FE  D  +L +IK + +  R      +VM  N FP I  W P             RI        + +  I  +HR +    N+ +DLID FL++Q    S ++K   F D  +  LI  LF AG ETT+ TL W  LL+  +PEIQ K++DEI + IG    P +  +K + Y  AV+ EI R++ ++P  + H    + +  G+F+P  + + P L +  RD + +KKP +FYPEHFL+  GN+      +PF  GKR C GE LA+ME F+     LQ F+
Sbjct:   16 CIFLFKFF-YGGEKGSQNFPPGPKP-------LPLIGNLHMINMKKPYLTFMELAEKYGPVFSVHLGANKAVVLCGTDAVKDALINYADEFSGRPKTPLFEQTFKGNGIVFADGENWKVMRRFTISTLRDFGMGKKTIEDRIIEESCCLVETFKSHKGKPFDNTMILNAAVANIIVHILLKHRFEYQDPTLLKLIKGVNENVRNG-ARPIVMLYNAFPSIIQWIPGTH---------KRIFANTQNFFNILKEIFIEHRDQL-DVNDQRDLIDTFLVKQQEEKSSSTK--FFHDENLKVLIGNLFAAGMETTSTTLRWGILLMMKYPEIQKKVQDEIDRVIGSAE-PRLEHRKLMPYTDAVVHEIQRFANLVPNGLPHATTTDVTFRGYFIPKGTQVIPLLTSVLRDKAYFKKPEEFYPEHFLDSKGNFLKNEAFLPFSAGKRTCAGETLAKMELFLFFTKLLQNFT 460          

Query:   23 CITVY-VFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNL--LNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGR-----WANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVM--NVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            CI +Y VFY     K S   P   KP       LP++GNL  +N+   PF    +L EKYGP++S+Q+G K ++VL   D +  +L    + FSGR     +    T  +   SG++F D E W   R FTL  LRDFG GK+  E+ +  E   +V+  K   G+  + T +++ +  N+I   ++   FE  D  +L +IKS+ +  R+     +VM  N +P I  W P  S   IY        +      +F+     +HR +    N+ +DLID FL++Q    S ++K   F D  +  L+S LF AG ETT+ TL W  LL+  +P+IQ K++DEI + IG    P +  +K + Y  AV+ EI R++ + P  + H    + +  G+F+P  + + P L +  RD + +KKP +FYPEHFL+  G +      +PF  GKR C GE LA+ME F+     LQ F+
Sbjct:   13 CIFLYKVFYGG--EKESQNFPPGPKP-------LPLIGNLHIMNMKK-PFLTFMELAEKYGPVFSVQLGTKKVVVLCGTDAVKDALVNHADEFSGRPKIPIYVFSLTHVIPICSGVIFADGENWKVMRRFTLSTLRDFGMGKKTLEDRIGEESGCLVETFKSHEGKPFDNTMILNASVANIIVHILLNHRFEYQDPTLLKLIKSVSENVRIGG-RPIVMLYNTYPSIMQWVPG-SHKSIY--------ENSQNLLNFLKETFTEHRHQL-DVNDQRDLIDTFLVKQQEEKSSSTK--FFHDENLTILLSNLFGAGMETTSTTLRWGILLMMKYPDIQKKVQDEIDQVIGSAE-PRLEHRKQMPYTDAVIHEIQRFANLAPNGLPHATTTDVTFRGYFIPKGTQVIPVLTSVLRDKAYFKKPEEFYPEHFLDSEGKFLKNEAFLPFSAGKRICAGETLAKMELFLFFTKLLQNFT 462          

Query:   23 CITVY-VFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNL--LNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVM--NVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            CI +Y VFY    +  S   P   KP       LP++GNL  +N+      ++ +L EKYGP++S+ +G    +VL   D +  +L    + FSGR      +   K +GI+F D E W   R FT+  LRDFG GK+  E+ +  E   +V+  K   G+  + T +++ A  N+I   ++K  FE  D  +L +IK + +  R      +VM  N FP I  W P             RI        + +  I  +HR +    N+ +DLID FL++Q    S ++K   F D  +  LI  LF AG ETT+ TL W  LL+  +PEIQ K++DEI + IG    P +  +K + Y  AV+ EI R++ ++P  + H    + +  G+F+P  + + P L +  RD + +KKP +FYPEHFL+  GN+      +PF  GKR C GE LA+ME F+     LQ F+
Sbjct:   13 CIFLYKVFYGG--KGASQNFPPGPKP-------LPLIGNLHMMNMKKPHLTFM-ELAEKYGPVFSVHLGANKAVVLCGTDAVKDALINYADEFSGRPKTPLFEQTFKGNGIVFADGENWKVMRRFTISTLRDFGMGKKTIEDRIIEESCCLVETFKSHKGKPFDNTMILNAAVANIIVHILLKHRFEYQDPTLLKLIKGVNENVRNG-ARPIVMLYNAFPSIIQWIPGTH---------KRIFANTQNFFNILKEIFIEHRDQL-DVNDQRDLIDTFLVKQQEEKSSSTK--FFHDENLKVLIGNLFAAGMETTSTTLRWGILLMMKYPEIQKKVQDEIDRVIGSAE-PRLEHRKLMPYTDAVVHEIQRFANLVPNGLPHATTTDVTFRGYFIPKGTQVIPLLTSVLRDKAYFKKPEEFYPEHFLDSKGNFLKNEAFLPFSAGKRTCAGETLAKMELFLFFTKLLQNFT 457          

Query:   23 CITVY-VFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNL--LNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVM--NVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            CI +Y VFY    +  S   P   KP       LP++GNL  +N+      ++ +  +KYGP++SIQ+G    IVL   D +  +L   G+ FSGR        ++K  G++F D E W   R F L  LRDFG G++  E+ +  E   +V+  K    +  + T +++ A  N+I   ++   FE  D  ++ +IKS+ +  ++A  + +VM  N +P I  W P              + +   + ++F+       R +    N+ +DLIDAFL++Q    S  S    F D  +  L+ +LF AG ETT+ TL W  L++  +P+IQ K++DEI + IG    P +  +K + Y  AV+ EI R++ ++P+ + H + E+ +  G+F+P  + + P L +  +D   ++KP +FYPEHFL+  GN+      +PF +GKR C+GE LA+ME F+     LQ F+
Sbjct:   13 CIFLYKVFYGG--KGASQNFPPGPKP-------LPLIGNLHMMNMKKPHLTFM-EFSKKYGPVFSIQLGLNKAIVLCGADAVKDALINHGDEFSGRPKIPVFDQISKGYGVVFADGENWKVMRRFALSTLRDFGMGRKTIEDTIVEESGCLVETFKSHEAKPFDNTLILNAAVANIIVHILLNHRFEYQDPTLIKLIKSVSENVKIAG-SPIVMLYNTYPSIMGWIPGSH---------KTVFENFQKLSNFLKETFTKRRDQL-DVNDQRDLIDAFLVKQQEEKS--SSKKFFHDENLKVLLGDLFAAGMETTSTTLRWGILMMMKYPDIQKKVQDEIDRVIGSAE-PRLEHRKQIPYTDAVIHEIQRFANLVPIVLPHSITEDVTFRGYFLPKGTQVIPLLISVMQDKDYFQKPEEFYPEHFLDSKGNFVKNEAFLPFSVGKRSCVGETLAKMELFLFFTKLLQNFT 457          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQY-LNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSG----ILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQD-IARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKK 1438
            I  V+F + V + ++ + R TS   P    P+P      P++GNLL V      Y L  L+ +YG ++S+Q+GWK ++V+N    + + L   G   + R      + L    G    +L      W  QR F++  LR+FG GK+  E+ V +E   +      + G+ I    +++ A  N+I+  I  R FE  D  ++ + K ++D +  ++ +   V+N+FPI    P +         P ++ Q        + +++ ++R  + P+   ++L DAFL E  ++    +   SF D  +  ++ +LF AG  TT+ TLSW  LL+ +HP++Q +++ EI   IG +R P M D+  + Y  AV+ E+ R+  + PL++      +  +  F +P  SIL PN+ +  +D +VW+KP  F+PEHFL+  G++      +PF  G+R CLGE LARME F+     LQ FS S+ +   +
Sbjct:   14 IFTVIFILLVDLMHR-HQRWTSRYPPG---PVP-----WPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIPEVLNMFPILLRIPGL---------PGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKG--NAESSFNDENLRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPEMADQARMPYTNAVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSVPNGQPR 477          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQY-LNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSG----ILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSI-QDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTL 1504
            I  V+F + V + ++   R TS   P    P+P      P++GNLL V      Y L  L+ +YG ++S+Q+ WK ++V+N    + + L   G   + R      + L    G    +L      W  QR F++  LR+FG GK+  E+ V +E   +      + G+ I    +++ +T N+I+  I  R FE  D  ++ ++K + Q +  V+ +   V+N FPI    PR++          + +Q        + +++ ++R  + P    ++L DAFL E  +  +  +   SF D  ++ ++ +LF AG  TT+ TLSW  +L+ +HP++Q +++ EI + IG +R P M D+  + Y  AV+ E+ R+  ++P+++      +  +  F +P  +IL PN+ +  +D SVW+KP  F+PEHFL+  G++      +PF  G+R CLGEALARME F+     LQ+FS S+ D   +       +G  G    P+ + L
Sbjct:   14 IFTVIFILLVDLTHQ-RQRWTSRYPPG---PVP-----WPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMAWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLA---------DKALQGQKSFIAILDNLLTENRTTWDPVQAPRNLTDAFLAEIEK--AKGNPESSFNDENLLMVVRDLFGAGMLTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPVNLPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSVPDGQPQPSN----SGVYGILVAPSPYQL 495          

Query:   11 VVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSS-APFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSI-QDIARVADVNSLVMNVF-PIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHS-FTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            V+L       F  F + ++      H  P P     LP +GNLL +           L+EKYG ++++ +G + +++L   D I ++L  Q   FSGR        + +  G++F   E W T R F+L  +RDFG GK+  E  +  E + +V+E+K   G  +  T        N+I   +    F+  D   L+++  I Q  + ++ ++S V  +F  I  +FP             +I + +    D+IG  VE HR    P +  +D ID +LL   R+    S +H+ F    +V  +  LF AG ETT+ TL ++FL++  +P +  K++ EI + IG  R PT++D+  + Y  AV+ EI R++ + P+ + H+V ++    G+ +P ++ ++P L +   DP  +++P  F PEHFL+ NG  +     +PF  GKR CLGE +AR E F+   + LQ FS++     + +D   L+  + G  + P  + ++F
Sbjct:    5 VLLLLALTTGFLIFLVSQSQPKTHGHFPPGP---RPLPFLGNLLQMDRRGLLSSFIQLQEKYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFPGAH---------RQISKNLQEILDYIGHSVEKHRATLDP-SAPRDFIDTYLL---RMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFLDANGALKTNEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLASPVAPENID---LIPNNSGATKTPPQYQIHF 489          

Query:   11 VVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQY-LNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLA---KDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQD-IARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSD 1426
            V +F +   +      R+ S        P+P      P++GNLL V      Y L  L+ +YG ++S+Q+ WK ++V+N    + + L   G   + R      + L    +  G++F      W  QR F+L  LR+FG G++  E  V +E   +      + G+ I    ++  AT N+I+  I  R FE  D  ++ ++K ++D +  ++ +   V+N FPI    PR++          + +Q+       + +++ ++R  + P    ++L DAFL E  +  +  +   SF D  +  ++ +LF AG  TT+ TLSW  LL+ +HP++Q +++ EI + IG +R P M D+  + Y  AV+ E+ R+  ++PL +      +  +  F +P  +IL PN+ + H D +VW+KP  F+PEHFL+  G++      + F  G+R CLGE LARME F+     LQ+FS S+ D
Sbjct:   12 VAIFTVIFILLVDLMHRRQSWTSCYPPGPVP-----WPVLGNLLQVDLNNMPYSLYKLQNRYGDVFSLQMAWKPMVVINRMKAMKEVLLTCGEDTADRPPVPIFEHLGFKPRSQGMIFAPYGPEWREQRRFSLSSLRNFGLGRKSLEEWVIKEAGHLCDAFTTQAGQYINPNTMLKKATCNVIASLIFARRFEYEDPYLIRMLKVLEDSLTELSGLIPEVINTFPILLHIPRLA---------DKFLQSQKSFIAIVDNLLTENRTTWDPAQSPRNLTDAFLAEIEK--AKGNPESSFNDENLRMVVIDLFTAGILTTSTTLSWALLLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPLHLPRITSRDIEVQDFLIPKGTILLPNMSSVHMDDTVWEKPLRFHPEHFLDAQGHFVKHEAFITFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPD 473          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQY-LNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSG----ILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDI-ARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQL 1456
            I  V+F + V + ++ +   TS   P    P+P      P++GNLL V      Y L  L+ +YG ++S+Q+GWK ++V+N    + + L   G   + R      + L    G    +L      W  QR F++  LR+FG GK+  E+ V +E   +      + G++I    +++ A  N+I+  I  R FE  D  ++ ++K +++    ++     V+N FPIF   P ++ M         + Q        + +++ ++R  + P+   ++L DAFL E  +  +  +   SF D  +  ++ +LF AG  TT+ TLSW  LL+ +HP++Q +++ EI   IG ++ P M D+  + Y  AV+ E+ R+  + PL +      +  +  F V   S L PN+ +  +D +VW+KP  F+PEHFL+  G++      +PF  G R CLGEALARME F+     LQ+FSIS+ D   +   +++
Sbjct:   14 IFTVIFILLVDLMHR-HQHWTSRCPPG---PVP-----WPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTEISGFIPGVLNEFPIFLRIPGLADM---------VFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTDAFLAEIEK--AKGNPESSFNDENLRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVQHPEMADQARMPYTNAVIHEVQRFGDIAPLPLPRITSRDIEVQDFLVTKGSTLIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGHRSCLGEALARMELFLFFTCLLQRFSISVPDGQPQPSNYRV 483          

Query:    2 MILVVLFCITVYVFYKFYL-RKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAP-FQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            +++ +L C+TV V    +  RK+   LP    P       LP +GN L +++   +  L  + E+YGP+++I +G + ++VL  +D + ++L +Q   FSGR        + K  G++F + E     R F++  LRDFG GK+  E  +  E   ++  ++   G NI+ T  +S    N+IS  +    F+  D+  L +++ +  I +    ++    ++ +F      S+M        +  Q +    DFI   VE H +R    N  +D ID+FL+         + N  F    +V     LF+ G ET + TL + FLLL  HPE++ K+ +EI + IG  R P   D+  + Y +AV+ EI R+  V+P+S+A RV ++     FF+P  + ++P L +  RDPS +  P DF P+HFLNE G ++     VPF +GKR C GE LARME F+   + +Q F +  S   K +D
Sbjct:    7 LLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTP-------LPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTST--GQLYEMFS-----SVMKHLPGPQQQAFQLLQGLEDFIAKKVE-HNQRTLDPNSPRDFIDSFLIRMQ--EEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDID 472          

Query:   80 PSHLKPIPVVSGGLPIVGNLLNV-SSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDI--------ARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLIS---ELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSI 1414
            P  L P P     +P +GNLL V + A FQ    LREKYGP++++ +G + +++L  ++ + ++L ++ + FSGR      +   +  G+   + E W   R F+L +LRDFG GK+  E  +  E   +++E +   G  I+ T  +S    N+IS  +    F+  D+  L +++ I +         A++ D+ S VM   P                   RI   I+   DFI + V+ +     P+N  +D ID FL++ H+      KN+  T++ +  L+     LF AG ET ++TL + FLL+  HPE+QTKI +EI++ IG  R P+++D+  + +  AV+ EI R + ++P+ + H V+ +    G+ +P  + +FP L +  +DP  +  P DFYP+HFL+E G ++     VPF  GKR CLGEA+ARME F+   S LQ FS+
Sbjct:   30 PGRLPPGPT---PIPFLGNLLQVRTDATFQSFLKLREKYGPVFTVYMGPRPVVILCGHEAVKEALVDRADEFSGRGELASVERNFQGHGVALANGERWRILRRFSLTILRDFGMGKRSIEERIQEEAGYLLEEFRKTKGAPIDPTFFLSRTVSNVISSVVFGSRFDYEDKQFLSLLRMINESFIEMSTPWAQLYDMYSGVMQYLP---------------GRHNRIYYLIEELKDFIAARVKVNEASLDPQN-PRDFIDCFLIKMHQ-----DKNNPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLIMKHPEVQTKIYEEINQVIGPHRIPSVDDRVKMPFTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPKGTDVFPLLGSVLKDPKYFCHPDDFYPQHFLDEQGRFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSILQNFSL 462          

Query:   44 YKFYLRKTSSALPSHLKPIPVVSG-GLPIVGNLLNVSSAPFQ----------------YLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVA-DVNSLVMNVFPIFDWFPRISLMLIYY--FHPMRIIQTIDRT-TDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDT 1447
            + +  R     +P    P PVV   G  ++   L   S P++                 L DL   YG I+S  IG   ++VLN++  + ++L +Q   FS R     T  + K  GI+F      W  QR F+   LR FG GK   E  +  E   + +E++           +V+ A  N+I      R F+  +     ++  +     V  +   L++N   I  W        +YY  F P + ++ I++  T F+  I++DHR+    EN  QD ID +LL        N+ N  F +  +  +I +LF+AG +TT N+L W  L +++HP IQ KI +EI++ IG  R P++ DK  + Y +A + E+ R STV+PLSI H   E   + GF +P  +I+ PNL++ HRDP++W+KP DFYP+ FL++ G    K   +PFG+GKR C+GE LA+ME F++ VS +Q F+  L  +SK + T
Sbjct:   48 WSWLWRLPERGIPPGPAPWPVVGNFGFVLLPRFLRRKSWPYRRARNGGMNASGQGVQLLLADLGRVYGNIFSFLIGHYLVVVLNDFHSVREALVQQAEVFSDRPRVPLTSIMTKGKGIVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFRYVKEEMQKHGDAPFNPFPIVNNAVSNIICSLCFGRRFDYTNSEFKQMLNFMSRALEVCLNTQLLLVN---ICSW--------LYYLPFGPFKELRQIEKDLTLFLKKIIKDHRESLDVEN-PQDFIDMYLLHVEE-EKKNNSNSGFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLHPNIQEKIHEEIARVIGADRAPSLTDKAQMPYTEATIMEVQRLSTVVPLSIPHMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEKPNDFYPDRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVLPKDSKPILT 524          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQY-LNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLA---KDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQD-IARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISL 1420
            I  V+F + V + ++   R TS   P    P+P      P++GNLL V      Y +  L+ +YG ++S+Q+GWK ++V+N    + + L   G   + R      + +    K  G++       W  QR F++  LR+FG GK+  E  V  E   +   +  + GR ++   L++ A  N+I+  I  R F+  D + + V+K +++ +     +   V+N+FP+     RI  +    F   +   T+      + ++V +H+K + P+   +DL DAFL E  +  +  +   SF D  +  ++++LF AG  TT+ TL+W  LL+ +HP++Q +++ EI + IG +R P M D+  + +  AV+ E+ R++ ++P+++ H+   +  + GF +P  + L PNL +  +D +VW+KP  F+PEHFL+  GN+      +PF  G+R CLGE LARME F+     LQ+FS S+
Sbjct:   14 IFTVIFILLVDLMHR-RQRWTSRYPPG---PVP-----WPVLGNLLQVDLCNMPYSMYKLQNRYGDVFSLQMGWKPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEWREQRRFSVSTLRNFGVGKKSLEQWVTDEASHLCDALTAEAGRPLDPYTLLNKAVCNVIASLIYARRFDYGDPDFIKVLKILKESMGEQTGLFPEVLNMFPVLL---RIPGLADKVFPGQKTFLTM------VDNLVTEHKKTWDPDQPPRDLTDAFLAEIEK--AKGNPESSFNDANLRLVVNDLFGAGMVTTSITLTWALLLMILHPDVQCRVQQEIDEVIGQVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471          

Query:   98 IPVVSGGLPIVGNLLNVSSAPF-QYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSL-VMNVFP-IFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNG 1465
            +P      PI+GN+L + +    + L    E YGP++++ +G K  +VL+ Y+ + ++L + G  F+GR +    + ++K  GI F + + W   R F+L  LR+FG GK+  E+ +  E   +V+E++  N    + T ++  A  N+I   I    F+  DE  L +++S+ +  R+     L V N FP + D+FP I   L+         +  D   +FI   V++H+K     N  +D ID FL++  + N+L      FT   +V  +S+LF AG ETT+ TL ++ LLL  HPE+  ++++EI + IG  R P M D+  + Y  AV+ EI R+  +LP ++ H V  +     +F+P  + +  +L +   D   +  P  F P HFL+E+GN++     +PF  GKR C+GE LARME F+ + S LQ F +    E K LD   ++NG
Sbjct:   29 LPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVYLGMKPTVVLHGYEAVKEALVDLGEEFAGRGSVPILEKVSKGLGIAFSNAKTWKEMRRFSLMTLRNFGMGKRSIEDRIQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHNRFDYKDEEFLKLMESLNENVRILSSPWLQVYNNFPALLDYFPGIHKTLL---------KNADYIKNFIMEKVKEHQK-LLDVNNPRDFIDCFLIKMEQENNL-----EFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPEVAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTRDVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGKRMCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNG 472          

Query:   50 FYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNE--NGN--YQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            FY  +  +++P  LK  P+   GLPI+G +  +      YL  L +K+GPI+ I++G +++++L+NYD+I K+L + G  FSGRW       +  DSGI+FKD + W+TQRSF L+VLRDFG GK  + ++V  E   +++E++   G+ I+ +K++   T N+IS FIM + FE  +  I  + K + +  +  D+  L+  +FP  D       ++I +    +    I    ++    +++H K     +E +DL+D FL++Q++L   N    SF DWQ++R   ELF AGYETT+ TL W+FL ++ H +IQ K+ +EI + IG  R PTMNDKKS+NY QAV+DEIFR S+V PL++ HR L +A+I+G+F+P ++++FPNLYACH D  +W+KP  FYPEHFL E  NGN  Y P+ EL+ F +GKRQCLGE+LARME FI   S LQ+F + L  E  + +  + L G  G  RG  ++   F
Sbjct:   17 FYGFQKRNSIPKGLKETPI-EYGLPILGIIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEI---QNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIF 503          

Query:   26 ITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFL----NENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            I  Y F + + R+   ++P+ LK  P+   G PI+G +  +      YL +L  K+GPI+ I++G +++++L NY  I K+L +    FSGRW       +  DSGI+FKD   W+TQRSF L+VLRDFG GK  ++++V  E   ++ E+    G  I+ +K++   T N+IS FIM + F+ +D  I ++  +I   ++ +D+   +  +FPIFD    IS   ++    +++   ++R        +E+H+      +E  DLID FLLEQ+RL+       SFTD Q++ +  E+F AGYETT+ TL W+ L ++ + +IQ K+ +EI   IG  R PTMNDKKSLNY QAV+DEI R S+V PL I HR   + S++ +F+P +S++F N YACH DP +W KP +FYPEHFL    N+   Y P+ EL+PFG+GKRQC+GE+LARME FI  VS LQ++ +  S+        + L G+ G  R   I    F
Sbjct:   12 IIWYCFSRVFKRR---SIPNGLKETPI-EYGWPILGIIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERV---FHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIF 503          

Query:  176 DLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQ--GNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQ-TIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLN-ENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDES-KKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            D R++YG + S ++G +  +VLN+Y  + ++L  Q  G+ FSGR  + +   L    GI+  + E W   R F L+VLRDFGF +   E+ +++E++ +  +        ++TT+++  A  N+IS  +      + D+     + + Q+  +  D+   +   FP+    P +  +L      + ++Q  +  T  F    ++ HR +    +   D +DAFL+EQ +LN    K+H+F D+Q+ R ++ELF+AG +TT+NT+ W  L   ++PE Q +++ EI  +IG  R P   D+K + Y  A +DE+ R++T+ P ++ HR   +    G+ + +D ++  NLY  H DP +W  P  F PE FL  + G YQP   LVPFG+GKR CLGE+LAR E F+ +   LQ+ S  L  +S K L+  ++  GS G    P  H + F
Sbjct:   70 DWRKRYGDLVSYRLGARRFVVLNSYAAVKEALASQEFGDVFSGRMNSNYINSLTHGKGIVSSEGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISVMLFGYRAGSQDDRFEAFLAATQENLQGGDLARFIPVGFPLLYQIPGVMRLLELLGVDVYVVQRNLKVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNG-RKKDHTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEIDAQIGRNRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCTRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTGEYQPNEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARLHPDSVKNLEDIKI--GSDGIVHAPGAHRIIF 516          

Query:  176 DLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQ--GNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQ-TIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLN-ENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDES-KKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            D R++YG + S ++G +  +VLN+Y  + ++L  Q  G+ FSGR  + +   L    GI+  + E W   R F L+VLRDFGF +   E+ +++E++ +  +        ++TT+++  A  N+IS  +      + D+     + + Q+  +  D+   +   FP+    P +  +L      + ++Q  +  T  F    ++ HR +    +   D +DAFL+EQ +LN    K+H+F D+Q+ R ++ELF+AG +TT+NT+ W  L   ++PE Q +++ EI  +IG  R P   D+K + Y  A +DE+ R++T+ P ++ HR   +    G+ + +D ++  NLY  H DP +W  P  F PE FL  + G YQP   LVPFG+GKR CLGE+LAR E F+ +   LQ+ S  L  +S K L+  ++  GS G    P  H + F
Sbjct:   70 DWRKRYGDLVSYRLGARRFVVLNSYAAVKEALVSQEFGDVFSGRMNSNYINSLTHGKGIVSSEGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISMMLFGYRAGSQDDRFEAFLAATQENLQGGDLARFIPVGFPLLYQIPGVMRLLELLGVDVYVVQRNLKVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNG-RKKDHTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEIDAQIGRDRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCPRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTGEYQPNEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARLHPDSVKNLEDIKI--GSDGIVHAPGAHRIIF 516          

Query:   14 VLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGT 1477
            V  C++V  F  F         P +  P P    G+P +G +  + + P + +     KYGP+ S+++G ++++VLNN++ I K+L  QG  FSGR        +    G+   D  + W TQR F    LR FG GK+  E+ +  E+E +   I+  NG+  +   ++  A  N     +M R F+ ++E    +I ++  +      NS ++ V     + P +  +  + +   + +  I+     +  IV +H  RF  +++ +D +DAF+ EQ +    N K+ SFTD Q+++ + +LF+AG ETT +TL W+ L L  +PE Q K+R EI K  G  R P M+DK  + Y  A + E+FRY T++PLS+ H   ++ S+NG+ +P  + + PNL+A H DP VW +P  F PE  L+E GN+     ++PF +G RQCLGE LARME FI +VS +QKF   L D ++  +  ++ NGS GT
Sbjct:    9 VSVCLSVVFFTGFLALCCWYKRPKNFPPGP---RGVPFLGVIPFLGNYPARVMQKWSRKYGPVMSVRMGSRDLVVLNNHENIQKALVMQGQIFSGRPNMPALTQVTDGLGLATIDYTDHWKTQRRFGQTTLRGFGVGKRSMEDRIVEEVEYLNNAIRSHNGKPFDILGILGNAVSNNTCSVVMGRRFDYDNERFKKIIATLSGLFTNPKSNSTIILVL----FMPFLMKIPPFSWINNKRVDGINEIKRLLREIVHEHELRF-DKDDVRDFMDAFIAEQKK----NDKHSSFTDLQLLQYVRDLFVAGTETTTSTLRWSILCLIHNPEKQEKLRKEIYKVTGQDRVPAMSDKAQMPYTCAFMQEVFRYRTLVPLSLFHATNDDVSLNGYRIPKGTTVLPNLWAVHNDPDVWDEPSKFKPERHLDEKGNFVQSKHVIPFSVGPRQCLGEQLARMEIFIFLVSMVQKFEF-LPDPNEP-NLPEIENGSCGT 483          

Query:  149 SSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNS-LNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNG 1465
              APF+      E YGP+ +  +G +  +VL  YD + ++L +  + F GR    F     K  G++  + E W   R FTL  LRDFG G++  E  +  E + +++ ++       + T  +S A  N+I   +  + F   D N L +++ I  + R    +        +++ FPR+  +L      +  I  ID    F    V+ H++   P+N  +D ID FL+   RLN   +  N  F    +   +  LFLAG ETT+ T+ +  +LL  HPEIQ +++ EI   IG  R P M D+KSL +  AV+ E+ RY  ++PL++ H  + + +  G+ +P D+++ P L++  RD   W+ P+ F P+HFL+ NGN++     +PF  GKR C+GE+LARME F+ +VS LQ F+ S       +DT   ++G
Sbjct:   47 GKAPFKTFLKWSETYGPVMTAYLGPQRTVVLVGYDAVKEALIDNADDFVGRAPIPFVMRALKGYGLVISNGERWRQLRRFTLTTLRDFGMGRKTMEGWIQEESKHLLEAVRETKSVPFDPTFPLSRAVSNVICALVFGQRFSYEDNNFLRLLQIIGGVLRFGSSS-----WGQLYNLFPRLVELLPG--KQLHFIDDIDELRRFAMLKVQKHQETLDPDN-PRDFIDCFLI---RLNQEKDMPNTEFHYDNMTATVMNLFLAGTETTSTTIRYALMLLIKHPEIQERMQKEIDSVIGQERSPMMEDRKSLPFTDAVIHEVQRYVDLVPLNVPHYAVRDITFRGYTIPKDTVILPMLHSVLRDKDHWESPWTFNPKHFLDNNGNFKKNPAFMPFSAGKRACVGESLARMELFMFIVSLLQNFTFSCPGGPDSMDTSPGVSG 475          

Query:   56 LRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVN-SLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            LR  SS   S   P P++      VGN+         ++  +  KYG I S+ +G K  I+LN   V  ++  + G  FSGR +    + + K  GI+       W  QR F L  LRDFG GK+  E  V  E   ++KE+  + G+       +  +  N+I   +    FE +D     +++ I +  R +    + + N+ PI  +FP     + +    +R          F+   VE HRK   PEN  +D IDA+L+E ++  S  +++ +F +  ++R  ++LF+AG ETTANTL W  + +  HP++Q +  +EI + +GF R+P+M+D+  L Y  A + EI RY+ ++PL + H+  +   + G+ +PA + +  NL A   D   WK P  F PE+FL+E G +      +PF LG R CLGE LAR E FI   S +Q+   S
Sbjct:   30 LRLNSSRSRSPPGPKPLL-----FVGNMPQFIKDKMGFIRSM-PKYGEISSLYLGRKPTIILNTMQVAKEAFVQNGTIFSGRPSLPLVRWVNKGYGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEAHFLIKEMLKQEGKAFYPIHPIMNSVSNIICSIVFGDRFEYDDRRFAKLLEIINENIRFSGSPVAQIFNLVPIIKYFPGPHQKIWHNLQSLR---------KFMSEEVEKHRKSLDPEN-LRDFIDAYLVEMNKQES--NEDSTFHEENMLRSTTDLFIAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGFDRFPSMDDRAQLPYTHATVHEIQRYANIVPLGVVHQTTQPTKLRGYHIPAGTNIMSNLTAILTDKDHWKYPDTFNPENFLDEKGQFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQQLKFS 467          

Query:   11 VVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVS--GGL---PIV-------GNLLNVSSAPFQ---YLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREI----EKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENI---LYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDR-TTDFIGSIVEDHRKRFCPENESQDLIDAFLLE---QHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSD 1426
            + +F +  ++F  F   +    +P    P+PVV   G L   P V       G+  N  + P      L  L   YG +YSI +G + ++VLN Y+++  ++      FS R        L K  GI+F      W  QR F    LR+FG GK   E  ++        +++K  +      ++ T L+S A  N+IS   + + F + DE     L ++ S  +I+   +  +L++N+FP   + P         F   + ++ ++R  T F+  I+  HR    PEN  +D ID +L+E   Q +   L  +   F++  +  +I +LF+AG +TT N++ W  L ++++P++Q K++ EI   +G  R P++ DK +L Y +A + E+ R + V+PLSI H   +     G+ +P  +++ PNL++ HRDP+VW+ P DF P  FL+E G        +PFG+G+R C+GE LA+ME F++  S +Q F+ SL +
Sbjct:   25 LAVFLVVFFLFRHFGRTRRFLNIPPGPTPLPVVGNFGSLVVPPFVLKLFARRGDYENSQAHPLSPQVGLMQLSRLYGNVYSIFVGNQLLVVLNGYEMVKDAMTNYAEVFSDRPDIPLVSILTKRKGIVFAPYGTVWRRQRKFCHTALRNFGLGKLSLEPCIHEGFTIVKAELLKRSQEAGAAGMDLTPLISNAVSNVISSISLGQRFHHQDEEFRTQLNLMASGLEIS--VNSPALLINIFPWLYYLP---------FGVFKQLRKVERDITAFLKKIIAKHRATLDPEN-PRDFIDIYLIEMLAQEKAAEL--EEGGFSEEYLFFIIGDLFIAGTDTTTNSILWLVLYMSLYPDVQEKVQKEIDAVVGSGRLPSLTDKGTLPYTEATIMEVQRMTVVVPLSIPHMASKTTEFRGYTIPKGTVIIPNLWSVHRDPTVWENPDDFCPSRFLDEQGQLLRSEYFIPFGIGRRVCMGEQLAKMELFLMFTSMMQAFTFSLPE 509          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQ-YLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSI-QDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQL 1456
            IL++ F + + +F +   RK     P +  P P     LP+ GN  N+       +L  +  KYG IYS+Q+G  + +V+N+Y ++ ++L +Q  TF+ R  N     + K  GI F +   W  QR FTL  L+ FG GK+  E+ + +E + + + I    G +      ++ A  N+I   +  R FE  D+  L ++  I + I     V + + N FP F     + LM   +     +     +   F+   +E HR  + P +  +D ID +L E  +    + +   F    +   + +LF+AG ETT+ TL W F+ +  +PEIQ K++ EI + IG  R P+M D+ ++ Y  AV+ E+ R   ++PL++     +  ++ G+ +P  + + PNL +   D + WK P+ F P++FLN  G +      +PF  GKR CLGE+LARME FI   S LQ F+ S    SK    F+ 
Sbjct:   19 ILLLSFIVFLLIFDQLKNRK-----PKNFPPGPT---SLPLFGNFFNLDHKQLHIHLTKMSRKYGRIYSLQLGGTHFVVVNSYSLVKEALVDQAETFADRPPNAVFHKINKCQGIAFNNGYSWKQQRRFTLSTLKSFGIGKRNLESSITQEFDFLHQAIINMKGESFNPHFFINNAVSNIICSLVFGRRFEYTDKKFLTMLSLISRAIQLEGSVWAQLYNAFPHF-----MGLMPGPH---QEMFSNFKQVEVFLNEEIEKHRAEWDPSS-PRDYIDCYLSEIEKRR--DDEEAGFNTEGLCYSVLDLFVAGTETTSTTLLWAFVFMMKYPEIQEKVQAEIDRVIGHSRQPSMADRPNMPYTDAVIHEVQRRGNIVPLNVPRMSTKETTLGGYSIPKGTQIIPNLTSVLFDETQWKSPHSFDPQNFLNNQGEFIRPDAFIPFSAGKRLCLGESLARMELFIFFTSLLQAFTFSPPAGSKSTLDFEF 485          

Query:    5 ILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIAR-VADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            + +V+  ++++V   F +  + +  P   KP       LP +GNL      P  Y+  +  KYG + S+ +G    IVLN   +  ++  + G  FSGR +   T+ L K  GI+       W  QR F L  LRDFG GK+  E  V  E   ++KE+  + G+    +  +  A  N+I   I    F+ +D+    ++  + D  R V    + + N+ P    FP             ++ +      +FI  +VE+HRK    EN  +D IDA+L+E  +  S  +++ +F    ++R I++LF AG ETTANTL W  + +  +P++Q +  +EI + +GF R+P+ ND+  L Y  A + EI R + + PL + H   +   + GF +PA + + PNL A   D   WK P  F PE+FL+E G +      + F LG R CLGE LAR E FI   S LQ+   S
Sbjct:   15 LALVVGLLSLFVLEIFRMNSSRNQSPPGPKP-------LPFLGNLPQFIKDPMTYIRSM-PKYGELCSMYLGRNPTIVLNTMQIAKEAFVQNGAVFSGRPSMPLTRWLNKGYGIVMAPYSNSWRQQRRFALHTLRDFGLGKKTVEERVAEEARYLIKEMLKEEGKPFYPSHPIMNAVSNIICSIIFGDRFDYDDKRFAKLLDILNDNVRLVGSPLAQIFNLLPFMKHFPGPH---------QKVWENDVALKEFIFEVVEEHRKTLDQEN-LRDFIDAYLVEMMKQES--NEDSTFHKENMLRSITDLFGAGTETTANTLRWGLIYMMDNPDVQERCHEEIVRVLGFDRFPSTNDRSHLPYTYATVHEIQRNANIAPLGVMHTTTQPTQLQGFHIPAGTDIVPNLTAILNDQEHWKYPDMFNPENFLDEKGQFCKNDSFLAFSLGPRVCLGETLARTELFIFFTSLLQQLRFS 467          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENND---ENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRII-QTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSD 1426
            +I + +FCI   V         ++  P    P P V   +P +GN+ ++   P   L+++ ++YG + S+ +G  +++ ++ Y  + + L  QG+ F+ R    F K +    GI+F    ++W   R FTL  LR+FG GK   E  +  E+  +++  K K G   +    ++ A  N+I   +  + +E +D   ++ L+++++  ++   + +   + N+FP    FP           P +II +++ ++  FI  I+ +      P  +   LIDA+L    +L   ++ N SF++  ++ L  +LF+AG ETT+ TL W  L + +HPEIQ +  +EI K +G  R P M D+ SL Y  AV+ EI R+S ++P    H    +     + +P  +I+  N+ +   D + WK PY+F PE+FL+E+G +      +PF  G R CLGE LA+ME F+   S LQ F     D
Sbjct:   24 LISLAIFCIIFLVLRAILQEVKATKRPLDFPPGPKV---IPFLGNV-SLFKKPDVALDEVTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQK-GSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVEN--NLQLQSGLLGTLCNIFPFLMDFPG----------PQQIIFKSMAKSKQFIRDIISERHATRDP-IKPMCLIDAYL---SQLEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLDEDGKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPD 482          

Query:   50 FYLRKTSSALPSHLKPIPVVSGGLPIVGNL--LNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWA-NVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVN-SLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPF-GLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            ++LR+     P    P P    GLP+VGNL  L++ + P   L+ L E YGPIYS+ +G   ++VL   ++I ++L  Q   F  R    VF K L    G+L      W  +R FTL +LR+FG G +  E  +  E E +V+ I+ K  +  +    ++ +  N+I        ++ N++  + ++  I +   ++  + S + N FP+  +FP             RI +       FI + +E+H      + E +D +DAF+    R+    + + +F+D  ++   + LF+AG ETT+ TL W  LL+  +P++Q ++++EI + +G  R P   D+  + Y  A + EI RY+ +LP++  H    +  + G+F+P  + +   +++  R+ S+W+ P  F P HFL+ +GN+  + + + F  +G R CLG+ LARME F+   + LQ+FS
Sbjct:   31 WWLRREQRGFP----PGPR---GLPLVGNLFQLDLKALP-ASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDRPEIPVFKKSLGNYEGLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWSQIFNSFPVLKYFPGPH---------QRINKNKVVLNAFIQARIEEHDMARI-QGEPRDYLDAFI--DKRIEDSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFLDIDGNFYNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRFS 469          

Query:  146 VSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGR-WANVFTKDLAKDSGI-LFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKF 1408
            + + P   + +L +KYG + +I +G   +++++ Y+ + + L  +G+ F+ R    +FTK L ++ GI L    + W  QR F L  LR+FGFGK    + +  E + +++  K +     +    ++ A  N+I   + +  ++ ++E    +   ++ + ++ A+   ++ NVFP     P      +++ H         +    +  IV +HR     ++  +DLID++L +  +    ++ N SFT   +++++ ELF+ G ETT+NTL W  L + ++P+IQ +   EI + +G  R P M D++SL Y  AV+ EI R+  VLPL + H   ++   N +  P  + +  NL +   D   WK P  F P+HFL+++G        +PF  G R CLGE+LA+ME F+   S LQ F
Sbjct:   55 ICNNPHIAMQELAKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTK-LTQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFK-QETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPFLLKLPG-PWQKVFHIH--------SKLQCLLNDIVSEHRATK-DQHNPRDLIDSYLAQIDK--EKDNPNSSFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFLDKDGQCIQSDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHF 464          

Query:  122 PIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEF---WATQRSFTLRVLRDFGF------GKQCA-ENVVYREIEKMVKEIKLKNGR--NIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTID-RTTDFIGSIVEDHRKRFCPENESQDLIDAFLL----EQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPK--VELVP-FGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            PIVGN+L +   P   L  + ++YG ++ + +G   ++VL+  + I ++L + G+ F+GR    ++  L  +   L   + +   W   +      LR+F        G  C  E  V  E E+++   K    +    +    ++ A  N++   +  + + + D   L ++   ++ ++++   +LV + FP     P   L         R ++ +  R   F+   +++H   +  +   +D+ DA +     ++H L  +       +D +VV    ++F AG++T    L+W  L L IHP++Q K++ EI + IG  R P   D+ +L   +A L E+FR+S  +P +I H   ++  +NG F+P D+ +F NL+  + DP+VW  P  F P+ FL+ +G    K  VE V  FGLGKR+CLG+ +AR E F+V+V+ LQ  S
Sbjct:   65 PIVGNILQLWPDPHLKLTRMCDRYGDVFRVHLGSVPVVVLSGLETIKRALVKNGDAFAGR-PPFYSLSLVGNGDTLTFTRAYDGCWKAHKRLARSALRNFCAAPARREGYACLLEECVCEEAERLLLACKGGGAQPGGFDPVPSITCAVANVMCALVFGKRYPHGDPTFLQIVGFNEEASQLSGAGNLV-DFFPFLRHVPNAQL---------RALKVLSARLLAFMEGHIKEHYSSY-QKGHVRDITDALIAMCAEQEHALREVG-----LSDERVVATALDIFGAGFDTIITGLTWCLLYLCIHPDVQHKLQREIDETIGRDRTPRFEDRANLRRVEAFLTEMFRHSAFVPFTIPHSTTQDVVLNGMFIPRDTCVFVNLHQVNHDPTVWSDPERFDPDRFLSHDGKEVNKEMVEKVQIFGLGKRRCLGDMVARQELFVVLVTLLQGLS 497          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSAL-PSHLKPIPVVSGGLPIVGNLLNVSSA-PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGI-LFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKF 1408
            +I + L C+ V++  +  L+   S + P    P P     LP++GN+   S   P   + +L +KYG + +I +G   +++++ Y  + + L  +G+ F+ R        L  + GI L    + W  QR F L  LR+FGFGK    + +  E   +++  K +     +   +++ A  N+I   +    ++ N+E    +   ++ + ++ A+   ++ NVFP     P      +++ H         +    +  IV +HR     ++  +DLID++L   H     ++ N SFTD  ++ L+ ELF+ G ETT+NTL W  L + ++P+IQ +  +EI K +G  R P M D++SL Y  AV+ EI R+  +LP  + H   ++   N +  P  + +  NL +   D   WK P+ F P++FL+++G        +PF  G   C GE+LA+ME F+   S LQ F
Sbjct:    5 LISLALICM-VFLTVRAALQVVGSTICPVGFSPGP---KPLPLLGNITAFSCKNPHIGMQELAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKLTHNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFK-QETSEFDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFPFLIKLPG-PWQKVFHIH--------TKLQCLLKDIVSEHRATK-DQHNPRDLIDSYL--AHIDKEKDNPNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFLDKDGQCIKSDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHF 460          

Query:  875 NHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDE--------ISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASIN-GFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSI 1414
            +  FT+ ++   +     A  + +++   W F ++A  P++  KIR+E        +S E+       ++  + + Y   V+ E  RY   + L + + V +N  ++  +  P  ++L P LY    DP V++ P +F PE ++  +   + K   + FG G   CLG+        I   + L KF++
Sbjct:  318 HREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELN------LDLIEKMKYTNMVIKETLRYRPPV-LMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYV----MITFAALLGKFAL 495          

Query:  122 PIVGNLLNVSSAPFQYLNDLREKYG-PIYSIQIGWKNIIVLNNYDVINKSL-KEQGNTFSGRWANVFTKDLAKD--SGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTD----FIGSIVEDHRKRFCPENESQDLIDAFL--LEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLD 1444
            P VGN   +     + L  L ++YG  ++ +Q+  K  ++++N  +  + L K+ G   + R +      ++++  S I  K    W  QR      LR +G G +  E ++ +E++ +        G  ++T   ++ + +N+I   +  + +  +D     ++ + + +A++A   +            P I +  + +F P+++++ +  T       I   + +HR+ +  E E +DL DA L  LE  +    N+     T+  ++  I+++F+AG+ETT   L W FL +A +PE+Q +I  E+   I F R P + D+KSL Y +A + E+ R S V PL I  +  +  +I G+ +P ++ ++ NL+A H D + W  PY F P  FL E  N      ++PFG G R C+GE+LA+ME F+ V   L +F ++L  +   ++
Sbjct:   36 PFVGNFPQIGPVLHKSLTSLGKQYGRGVFQVQLLGKRFVIIDNIKLARQVLLKKNGRDVADRTSAYVIDAISRNGCSVIFGKYSPTWKLQRRVVHSALRMYGSGVRILEALILQEVDNLCDIFANSQGAPVDTKLPLTLSVMNVICALVFGKRYGLDDAEFTDIVATTESMAKLASPEN------------PLIYMPWLRFF-PLQVVKKMKETVTARDRLIQRKITEHRETY-KEGEIRDLTDALLKSLEDAKQED-NNAMSLLTEDHLLIAINDVFMAGFETTTTALRWIFLYVAAYPEVQARIHQELDDVISFGRDPLIADRKSLPYLEATILEVLRISPVFPL-IRRKARKQLNIGGYCIPEETFVYVNLWAIHHDEAEWVDPYKFRPSRFL-EGTNSASAYSMLPFGAGVRVCVGESLAKMELFLFVSRLLHRFKLNLKGQCPDME 469          

Query:  128 VGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGR--WANVFTKDLAKDSGILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLN--SKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKV--ELVPFGLGKRQCLGEALARMEEFIVVVSFLQKF 1408
            +GNL  +S        +L + YG +Y + +G K  IVL+  D I ++L  Q   F+GR          L +  G+   D  E W   R      ++ +G  +   ++V+  E+ ++   ++   G+  + T+    A  N+I   +    ++ +D   L V +    ++R+    +LV N+FP       ++ +L +      +IQ      + +    ++H K F PEN  +D  DA L  +      +  SK H      ++  ++ LF+AG ETT+ TL W  + L  +P++Q ++  EI   IG   +P ++ +K L   +A   E  R + + PL+I H+  E +++ GF +P  + +F NL++ H DP+VWK P+ F  + FL+E G ++  V    +PFG G R CLGE LAR E F+ +   LQ+F
Sbjct:   37 IGNLNLLSKQMHLSFTELEKTYGKVYRLYLGHKLAIVLSG-DAIKEALVRQPRNFAGRPVLNPQLKSALNRGPGLTVMDYGETWKLFRKLGHSTIKVYGENR--LQDVIKDEVLELCNRLESSAGKPFDITQQSGIAVTNVICTKLFGTRYQIDDPEFLRVYEIHDKLSRIGFGGNLVTNIFP------SLASILPFSEKQRDLIQIGQERYEILERKYQEHVKTFDPEN-IRDYTDALLKAKQDAEQEDKSSKEHLQESTIIMAGLATLFIAGSETTSTTLGWAVIYLLHNPDVQERLHKEIDDVIGRDAFPQLSKRKELPVLEAFTAETLRLANLAPLAIPHKARERSTLQGFEIPEGTTVFANLWSLHHDPTVWKDPFTFNLDRFLDEEGKFKAPVGGTFLPFGAGPRVCLGEVLARSELFLFLSRMLQRF 460          

Query:  128 VGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDS-GILFKDKEFWATQRSFTLRVLRDFGF-----GKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRF----CPENESQDLIDAFLLEQHRLNSL-NSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIR---DEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVE--LVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSD 1426
            +GNL  +SS P   L  L + YGPIY++ +G +  +VLN+YD+  ++L ++GN F+GR  +      ++D  G+ F++  +  T R     +++   F       +  + ++ +E++ + K + +   ++ +    V+FA  N++        ++  ++    +++S+          S + + FP   + P        +    R+ + +    D +     DH K           ++DL  A + E ++ N   NS++ + T   V+  ++++ +AG ET   TL W    L  +P++Q + +   D++S+ +  + W     +K L Y +A + E+ R + V+PL+I H  + + ++ G+ +P  + +  NL+A   DP VW  P +F PE FL+  G +         P+G+G R C GE LARME F+  V  L+ F    S+
Sbjct:   39 IGNLHLLSSKPHLDLTRLGDIYGPIYTLNMGSQLAVVLNSYDIAKEALMKRGNAFAGRPHHFVGSKFSRDGKGVGFQN--YTPTLRRQQKTIMKTVKFFDTLKTGESLQEIITKEVDYLCKRLLIFGDQSFDPRHEVTFAAGNVVGRITFGERYKGGNKEFWQLMESLTIFVEGLTATSFI-DAFPFLKYVP--------FSMVKRVEKAVKLRDDVLNDKFRDHLKNLQNSTISTTTNRDLTYALIDEANKTNCFANSQSDALTIDHVIMTMNDMIMAGSETPTMTLLWILYFLVKYPDVQVRAQEQVDDVSRNVQPLAW---EGRKRLPYLEAFIAEVLRITGVMPLAIQHLAMADTALAGYHIPKGTTVIVNLWAMGHDPKVWDAPMEFRPERFLDSRGGFSTASTEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRASE 473          

Query:  137 LLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSG--ILFKD-KEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENES--QDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVEL--VPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISL 1420
            +L +   P   L +L + YG ++ +++G   I+V+N+ +   ++L  + N F+GR   ++T  L   +G  I F D    W  QR      LR FG G +  E  +  E ++++K + L  GR       V+ A +N+I  F+    ++ +D     V+   +   +     SLV + FP     P   L         R I+   +  D +  + + +++          +DL DA LL  ++ +   S     T+  ++  ++++F AG ETTA ++ W+ + L  +P++Q ++  +I + +G  R P ++D+++L   +A + E+ R S+++PL   H    +  + G+ VP D+I+  N++  H DP  W  P +F P  FL++ G +     L  +PF  G+R CL E+L +M+ F+ +   L KF  S+
Sbjct:    1 MLQMGPTPHLGLTELAKSYGEVFRLKVGSHRIVVVNSIEAAREALVRRANDFAGR-PMLYTASLISRNGTDIAFGDFGPLWKQQRKIAHSALRMFGSGLKPLEEKITVEADELIKRLSLVEGRAHNPKDDVNLAVLNIICSFVFGSRYDMDDPEFHTVVDYTEQFVQGFRAASLV-DYFPWLRHLPNKGL---------RQIKEACQNRDVV--LQKKYQEHLVTYEHGVIRDLTDA-LLSANKASQEESAYLPMTEDHIIMTMNDIFSAGLETTATSILWSLVYLIRNPKVQEQLHQQIDEVVGRDRAPELSDRENLPLIEATIAEVLRSSSLVPLLFPHSTTTDTHLRGYEVPKDTIVLFNVWNMHHDPQRWSNPDEFDPTRFLDDKGKFICPATLSYLPFSAGRRVCLAESLGKMQLFLFISRLLHKFRFSV 421          

Query:   98 IPVVSGGLPIVGNLLNVSSAPFQY-LNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQG-NTFSGR-------WANVFTKDLAKDS---GILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHS-FTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVE--LVPFGLGKRQCLGEALARMEEFIVVVSFLQKFS 1411
            +P     LP++GNLL++ S+   + L +L + +G I  I++    I+V+ +  +  + L  +  N F+GR       + +   KD+A +    G+++K K   +  R +        G       + + +E+ K+  ++    G  +++        +N+I  F+  + F+  D      ++ +        +++ +++ FP    FP   L     F   RI +  D+    +G+I+  H++ F  EN  +DL DAFL  +  +   + K     TD +V  ++ +++LAG ETT  +L W    L  + E+Q++++  I   IG  R P M+D++ L Y +A++ E+ R S  +PL + H+ + + +I+G+ +P  + +  NL+A H DP  W +P  F P+ F+NE+G ++   +   +PF  G+R CLGE+LA+ME F+++   LQ+F+
Sbjct:    1 MPPGPTPLPLIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLRKY----FPSLG-------DTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLSGKAFDKEDPEFSETLELVTKTVDTLSMSASILDAFPFLIHFP---LQASKNFK--RIAELRDK---LMGNILTFHKETFN-ENHIRDLTDAFLKAKLDIEREDKKAAGEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIG-DRRPLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFINEDGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQFT 432          

Query:  128 VGNLLNVSSA-PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            +GNLL +    PF+ + +L + YGP+ +I +GW+  + L  YD + ++L +Q + F GR    F     +  GI   + E W   R F L  LRDFG G++  E  +  E   +   I    G+  + T L+S A  N+I   +    F  +D+  L ++K I +I          + N+FP   W     LM     H   I   I+   +F    +++H+    P +  +D ID FLL   +    ++    F    ++ ++  LFLAG ETT++T+ +   +L  HP+IQ K+++EI   IG  R P+M D+KSL +  AV+ E+ R+  + P S+ H  L++ S  G+ +P D+++FP L++  R+  +W  P+ F P++FL++NGN++     VPF  GKR C+GE+LARME F+ +VS LQ F+ S
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTYGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAHINSLKGKPFDPTFLLSCAVSNVICCLVYGERFNYDDKQFLELLKMISEILGFNGGPKGAMYNLFP---W-----LMERLPGHQHTIFGYIEDIRNFAKKKIQEHKDTLDPSS-PRDFIDCFLLRMDQ--EKDNPTSEFHYENLLAMVQNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEDRKSLPFTDAVIHEVQRFMDLAPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLDQNGNFKKNPGFVPFSAGKRACVGESLARMELFVFIVSLLQNFTFS 460          

Query:  128 VGNLLNVSSA-PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            +GNLL +    PF+ + +L + YGP+ +I +GW+  + L  YD + ++L +Q + F GR    F     +  GI   + E W   R F L  LRDFG G++  E  +  E   +   I    G+  + T L+S A  N+I   +    F  +D+  L ++K I +I          + N+FP   W     LM     H   I   I+   +F    +++H+    P +  +D ID FLL   +    ++    F    +V  +  LFLAG ETT++T+ +   +L  HP+IQ K+++EI   IG  R P+M D+KSL +  AV+ E+ R+  + P S+ H  L++ S  G+ +P D+++FP L++  R+  +W  P+ F P++FL++NGN++     VPF  GKR C+GE+LARME F+ +VS LQ F+ S
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTYGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAHINSLKGKPFDPTFLLSCAVSNVICCLVYGERFNYDDKQFLELLKMISEILGFNGGPKGAMYNLFP---W-----LMERLPGHQHTIFGYIEDIRNFAKKKIQEHKDTLDPSS-PRDFIDCFLLRMDQ--EKDNPTSEFHYENLVSTVLNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEDRKSLPFTDAVIHEVQRFMDLAPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLDQNGNFKKNPGFVPFSAGKRACVGESLARMELFVFIVSLLQNFTFS 460          

Query:  128 VGNLLNVSSA-PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARV-ADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            +GNLL +    PF+ + +L + YGP+ +I +GW+  + L  YD + ++L +Q + F GR    F     +  GI   + E W   R F L  LRDFG G++  E  +  E   +   I    G+  + T L+S A  N+I   +    F  +D+  L ++K I +I          + N+FP   W     LM     H   I   I+   +F    +++H+    P +  +D ID FLL   +    ++    F    +V  +  LFLAG ETT++T+ +   +L  HP+IQ K+++EI   IG  R P+M ++KSL +  AV+ E+ R+  + P S+ H  L++ S  G+ +P D+++FP L++  R+  +W  P+ F P++FL++NGN++     VPF  GKR C+GE+LARME F+ +VS LQ F+ S
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTYGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAHINSLKGKPFDPTFLLSCAVSNVICCLVYGERFNYDDKQFLELLKMISEILGFNGGPKGAMYNLFP---W-----LMERLPGHQHTIFGYIEDIRNFAKKKIQEHKDTLDPSS-PRDFIDCFLLRMDQ--EKDNPTSEFHYENLVSTVLNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEERKSLPFTDAVIHEVQRFMDLTPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLDQNGNFKKNPGFVPFSAGKRACVGESLARMELFVFIVSLLQNFTFS 460          

Query:  128 VGNLLNVSSA-PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            +GNLL +    PF+ + +L + +GP+ +I +GW+  + L  YD + ++L +Q + F GR    F     +  GI   + E W   R F L  LRDFG G++  E  +  E   +  +I    G+  + T ++S    N+I   +    F  +D+  L +++ I ++ R    NS  M    +++ FP +   L    H   I   I+    F  + +++H+ +  P +  +D ID FLL   +    ++    F    +V  +  LFLAG ETT++T+ +   +L  HP+IQ K+++EI   IG  R P+M ++KSL +  AV+ E+ R+  + P S+ H  L++ S  G+ +P D+++FP L++  R+  +W  P+ F P++FL++NGN++     VPF  GKR C+GE+LARME F+ +VSFLQ F+ S
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTHGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAKINTFKGKPFDPTFILSCTVSNVICCLVYGERFNYDDKQFLELLQIISEVPRF---NSSPMGA--MYNLFPWLMERLPGRQH--TIFGYIEDIRKFAKNKIQEHKDKLDPSS-PRDFIDCFLLRMDQ--EKDNPTSEFHYENLVSTVLNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEERKSLPFTDAVIHEVQRFMDLTPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLDQNGNFKKNPGFVPFSAGKRACVGESLARMELFLFIVSFLQDFTFS 460          

Query:  128 VGNLLNVSSA-PFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSIS 1417
            +GNLL +    PF+ + +L + +GP+ +I +GW+  + L  YD + ++L +Q + F GR    F     +  GI   + E W   R F L  LRDFG G++  E  +  E   +  +I    G+  + T ++S    N+I   +    F  +D+  L +++ I ++ R    NS  M    +++ FP +   L    H   I   I+    F  + +++H+ +  P +  +D ID FLL   +    ++    F    +V  +  LFLAG ETT++T+ +   +L  HP+IQ K+++EI   IG  R P+M ++KSL +  AV+ E+ R+  + P S+ H  L++ S  G+ +P D+++FP L++  R+  +W  P+ F P++FL++NGN++     VPF  GKR C+GE+LARME F+ +VSFLQ F+ S
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTHGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAKINTFKGKPFDPTFILSCTVSNVICCLVYGERFNYDDKQFLELLQIISEVPRF---NSSPMGA--MYNLFPWLMERLPGRQH--TIFGYIEDIRKFAKNKIQEHKDKLDPSS-PRDFIDCFLLRMDQ--EKDNPTSEFHYENLVSTVLNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEERKSLPFTDAVIHEVQRFMDLTPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLDQNGNFKKNPGFVPFSAGKRACVGESLARMELFLFIVSFLQDFTFS 460          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNFDELVH 1525
            MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNFDELVH
Sbjct:    1 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNFDELVH 508          

Query:   14 VLFCITVYVFYKFYL----RKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGN----YQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            + +C+T  + + ++L    RK    +P  LK IP+ SG LPI+G +  +      YL  L  K GPI+ I++G + I+VLNNY++I K+L +  N FSGRW+  F K++  DSGI+FKD + WATQRSF L+VLRDFG GK  +  +V  E    + E+   +G+ ++ ++L+   T N+IS FIM + F  +D NI  + ++I +  +  D+  L++ +FP FD    I   LIY        ++  +  ++ G  +E+HR      +E +DL+D FL++QH L        SF DWQ++R   ELF+AGYETT+ TL+W  L ++ +P+IQ K+  EIS+ IG  R PTMNDKK+LNY QAV+DE+ R S+V P+ + HR  ++A+INGF++P DS++FPNLYACH DP +W+ P  FYPEHFL+ + N    YQP+ EL+PF +GKRQCLGE+LAR E FI  VS +Q+F IS ++E  +    Q + G+ G  R   I    F
Sbjct:    3 LCYCVTFILIFLYFLYWVCRK--PPIPKGLKEIPMESG-LPIIGAIHKIEPPMHHYLLKLGRKLGPIFRIKLGMRKIVVLNNYEMIKKALIDDANNFSGRWSQRFIKEITHDSGIIFKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNIQLIEETINNSTKNKDIIQLILLMFPCFDNSSLIC-QLIYLLTSKW--KSFVKIQNYFGEEIEEHRTNLDLTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRTSVELFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEDKYSQTIIGNEGVIRTSDIKNFLF 503          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSG--GLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGN----YQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGP 1489
            +++ +   I +Y   KF+  +++S      K + ++ G  G P++GN+ + +   +  L    + YG ++   +G ++I++L++  ++ K+LKEQGN FSGR+ N   K   ++SGILF +KE+WATQRSF L+VLRDFGFGKQ ++ +V  E   ++K+I+ + G+ +    L   ATVN+I+  +M   FE++ ++   + K I+   +  +    +  ++PI D  P I+  L+++    +   T   T+ FI +I++DH+KRF  ENE +D ID FL EQH+LN    KNH+FTD Q++R++ ELF AGYETT+ TLSW+ LLLA HP IQ K+  EI   +G  + P   DKK L Y QAV+DEI R STV+PLSI+HRV EN  ++G ++P DSI+FPNL+ACHRD +VW+KP++FYPEHFLN N +    Y P+ ELVPF +GKRQCLGE LAR+E FI +   +QKF I   +E  + +  ++  G+ G  R P
Sbjct:    5 VLIFITLGIALYFIKKFFFNQSAS------KNLNLLQGPTGWPLIGNINSFNEPLWMVLYKYSKHYGSLFKYTMGRRDIVILSSSKMLFKTLKEQGNNFSGRFQNFLIKARTRNSGILFTEKEWWATQRSFALKVLRDFGFGKQRSQEIVSNECMILLKDIEEECGKVVSARSLFPKATVNVIAKLVMNMRFESDSKDFTELTKLIEKAIQNNNFILTLFQMYPILDNMPFIAPFLLWWSGRNK---TAKITSKFINNIIDDHKKRFNIENEGEDFIDIFLKEQHKLNEEKVKNHTFTDQQLIRVVLELFFAGYETTSTTLSWSMLLLAKHPNIQEKVYQEIVDLLGTEKLPNFADKKCLQYTQAVMDEILRVSTVVPLSISHRVFENTEVDGVYIPKDSIIFPNLFACHRDENVWEKPFEFYPEHFLNINNSGQLKYTPRDELVPFSIGKRQCLGEGLARIEFFIFLTGIIQKFKIRFENEISEEEFAKITRGTDGGIRAP 497          

Query:   14 VLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRW-ANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFL----NENGNYQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGPAIHTLNF 1510
            V F +    FY +  +KT   +P  LK IPV SG LPI+G +  +     +Y   L  K GPI+ I++G + I+VLNNY++I K+L +  N FSGRW   VFT D A DSGI+FKD   WA QRSF L+VLRDFG GK  +  ++  E    + E+   +G+ +E ++L+   T N+IS FIM + F  +D  + ++ K+I ++ +  D+  L++ +FP FD     S ++       +   TI+   ++    +E+HR      +E +DL+D FL++Q +L        SF DWQ++R   E+F+AGYETT+ TL+W  L ++ +P+IQ K+  EIS+ IG  R PTMNDKK+LNY QAV+DE+ R S+V+P+++ HR   +A+INGF++P DS++FPNLYACH DP +W+ P  FYPEHFL    NE   YQP+ EL+PF +GKRQCLGE+LAR E FI  VS +Q+F IS ++E  +    Q + G+ G  R   I    F
Sbjct:    7 VTFILISLFFYYWTFKKTQ--IPKGLKEIPVESG-LPIIGAIHKIEMPISRYFQKLSRKLGPIFRIKLGMRKIVVLNNYEMIKKTLIDDANNFSGRWLPKVFT-DAAHDSGIMFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNFLDELDTLSGQIVEFSELIPIYTTNIISRFIMNKRFTRDDPKVQFIGKTITNLTKSKDILQLILIMFPCFDTSSLFSKLVFLLNTKWKRFVTIE---NYFWEEIEEHRTNLDLTSEGEDLMDRFLIKQRQLKQSTGNVESFVDWQLIRNSVEIFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVVPMALIHRTFYDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNEISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEEKYLQTIIGNEGHIRTSDITKFKF 503          

Query:    2 MILVVLFCITVYVFYKFYLRKTSSALPSHLKPIPVVSGGLPIVGNLLNVSSAPFQYLNDLREKYGPIYSIQIGWKNIIVLNNYDVINKSLKEQGNTFSGRWANVFTKDLAKDSGILFKDKEFWATQRSFTLRVLRDFGFGKQCAENVVYREIEKMVKEIKLKNGRNIETTKLVSFATVNMISDFIMKREFENNDENILYVIKSIQDIARVADVNSLVMNVFPIFDWFPRISLMLIYYFHPMRIIQTIDRTTDFIGSIVEDHRKRFCPENESQDLIDAFLLEQHRLNSLNSKNHSFTDWQVVRLISELFLAGYETTANTLSWTFLLLAIHPEIQTKIRDEISKEIGFIRWPTMNDKKSLNYCQAVLDEIFRYSTVLPLSIAHRVLENASINGFFVPADSILFPNLYACHRDPSVWKKPYDFYPEHFLNENGN----YQPKVELVPFGLGKRQCLGEALARMEEFIVVVSFLQKFSISLSDESKKLDTFQLLNGSRGTFRGP 1489
            +I+V+   + +Y   K   R    ++P  LKP+   SG  P++GNL  +    + +L     KYGP++   +G ++I+V+++  +++K+LKE+G  FSGRW N+    L  +SGILF D E+WATQRSF L+VL+DFGFGKQ +  ++  E   ++KEI+   G+ I    L    TVN+I+   M   FE +  N  ++  +++ +A+  +    ++ ++PI + +PRI+ +L+ +       Q  +       +I+E+H+KRF  ENE +D ID FL E++ L++    NH+FTDWQ+VR+I ELF+AGYETT+ TL+WT +L+A + EIQ K+  EI   IG  R P ++DKKSL Y QAV+DEIFR ++V+PLS+ HR+LEN+ ING F+P +SI+FPNLYACHRD  VWK+P++FYPEHFL E  N    Y P  ELVPF +GKRQCLGEALARME FI   S +Q+F +    E       ++  G+ GT R P
Sbjct:    7 VIVVIALALPIYFLSKLMTR---PSIPKGLKPLQGPSG-WPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAITLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGRE---QEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWTMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTEESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAP 499