2-oxoisovalerate dehydrogenase subunit alpha
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012717 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Human
Match: BCKDHA (branched chain keto acid dehydrogenase E1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:986]) HSP 1 Score: 512.301 bits (1318), Expect = 1.710e-179 Identity = 241/384 (62.76%), Postives = 299/384 (77.86%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HYLL+QGWW E +EK WR ++R+ V++A E+ E+ PNP LF DVY +MP +L KQ
Sbjct: 42 QQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQ 423
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Human
Match: AC011462.1 (novel protein) HSP 1 Score: 512.301 bits (1318), Expect = 5.524e-179 Identity = 241/384 (62.76%), Postives = 299/384 (77.86%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HYLL+QGWW E +EK WR ++R+ V++A E+ E+ PNP LF DVY +MP +L KQ
Sbjct: 76 QQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQ 457
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Human
Match: BCKDHA (branched chain keto acid dehydrogenase E1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:986]) HSP 1 Score: 497.278 bits (1279), Expect = 1.318e-173 Identity = 241/409 (58.92%), Postives = 299/409 (73.11%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTY-------------------------RVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTY R+G HSTSDDS AYRSVDE+++WDK D+PISRL+HYLL+QGWW E +EK WR ++R+ V++A E+ E+ PNP LF DVY +MP +L KQ
Sbjct: 20 QQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYSSSPILPPDPHSREPTLTWGPLPLCRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQ 426
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Human
Match: BCKDHA (branched chain keto acid dehydrogenase E1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:986]) HSP 1 Score: 372.474 bits (955), Expect = 2.167e-126 Identity = 188/318 (59.12%), Postives = 225/318 (70.75%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKH 1076
Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP+ GRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK
Sbjct: 42 QQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPH-----------------------------GRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQ 328
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Human
Match: BCKDHA (branched chain keto acid dehydrogenase E1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:986]) HSP 1 Score: 205.297 bits (521), Expect = 6.451e-63 Identity = 106/210 (50.48%), Postives = 135/210 (64.29%), Query Frame = 3
Query: 201 KFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREA-------------------------------GVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEG 737
+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREA GV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEG
Sbjct: 2 EFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAEARPHHVAQAGLQLLGSSDPPTSASQSAGITGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEG 211
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Celegans
Match: bckd-1A (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O45924]) HSP 1 Score: 464.537 bits (1194), Expect = 2.485e-161 Identity = 228/426 (53.52%), Postives = 290/426 (68.08%), Query Frame = 3
Query: 72 IMHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIE--------GISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQ-NGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
+MH + L SR +S V D + S+Y H K F +E + +YRV N G ++ + DPN ++T ++M+K MT LNI DRI+YDSQRQGRISFYMT+FGEEG +GSA AL+ DL++GQYREAGV LWRGYT+E +NQCYGN +D GKGRQMP+H+ K+ N +ISSPL TQL A G+AYAFK+ + N V YFGDGAASEGDAHAA NF++TL CP+IFFCRNNGYAISTPTSEQY GDGIA + YG+ IRVDGND+ AVYNATK AR + + NRPVLIEAMTYR+G HSTSDDS AYRS DE+ W D+PI+R K Y+ +GWW+E +E W+ E +K V+ EK + +LFEDVYD++P RL +Q + + + + K+ +P
Sbjct: 1 MMH--RALLNASRRVATVRSMASTVEGDAFRLSEYSSKYLGHRKAAFTEKLEIVNADDTPALPIYRVTNAVGDVIDKSQDPNFDEQTSLKMYKTMTQLNIMDRILYDSQRQGRISFYMTSFGEEGNHVGSAAALEPQDLIYGQYREAGVLLWRGYTMENFMNQCYGNADDLGKGRQMPMHFGTKERNFVTISSPLTTQLPQAVGSAYAFKQQKDNNRIAVVYFGDGAASEGDAHAAFNFAATLKCPIIFFCRNNGYAISTPTSEQYGGDGIAGKGPAYGLHTIRVDGNDLLAVYNATKEARRVALT-NRPVLIEAMTYRLGHHSTSDDSTAYRSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEMEWQKEVKKRVLTEFAAAEKRKKAHYHDLFEDVYDELPLRLRRQRDELDAHVAEYKEHYP 423
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Celegans
Match: bckd-1A (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O45924]) HSP 1 Score: 464.151 bits (1193), Expect = 3.051e-161 Identity = 217/383 (56.66%), Postives = 278/383 (72.58%), Query Frame = 3
Query: 177 RSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQ-NGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
++ +T L+ + D + +YRV N G ++ + DPN ++T ++M+K MT LNI DRI+YDSQRQGRISFYMT+FGEEG +GSA AL+ DL++GQYREAGV LWRGYT+E +NQCYGN +D GKGRQMP+H+ K+ N +ISSPL TQL A G+AYAFK+ + N V YFGDGAASEGDAHAA NF++TL CP+IFFCRNNGYAISTPTSEQY GDGIA + YG+ IRVDGND+ AVYNATK AR + + NRPVLIEAMTYR+G HSTSDDS AYRS DE+ W D+PI+R K Y+ +GWW+E +E W+ E +K V+ EK + +LFEDVYD++P RL +Q + + + + K+ +P
Sbjct: 41 KAAFTEKLEIVNADDTPALPIYRVTNAVGDVIDKSQDPNFDEQTSLKMYKTMTQLNIMDRILYDSQRQGRISFYMTSFGEEGNHVGSAAALEPQDLIYGQYREAGVLLWRGYTMENFMNQCYGNADDLGKGRQMPMHFGTKERNFVTISSPLTTQLPQAVGSAYAFKQQKDNNRIAVVYFGDGAASEGDAHAAFNFAATLKCPIIFFCRNNGYAISTPTSEQYGGDGIAGKGPAYGLHTIRVDGNDLLAVYNATKEARRVALT-NRPVLIEAMTYRLGHHSTSDDSTAYRSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEMEWQKEVKKRVLTEFAAAEKRKKAHYHDLFEDVYDELPLRLRRQRDELDAHVAEYKEHYP 422
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Celegans
Match: pdha-1 (Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P52899]) HSP 1 Score: 134.42 bits (337), Expect = 1.234e-34 Identity = 105/343 (30.61%), Postives = 161/343 (46.94%), Query Frame = 3
Query: 279 DNDPNIS----KETLIEMFKKMTLLNIFDRIMYDSQRQGRI-SFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGN--KNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAI------STPTSEQY-RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPR 1262
DN PN S +E ++ ++ M ++ + + ++ +I F G+E +G A+ + D V YR G G T+ +L + G N GKG M + YT N + + +G Q AG A A K R Q +C V +GDGAA++G A N + D P++F C NNG+ + S+ ++E Y RGD + I VDG DI AV ATK A+ C + P+++E TYR HS SD +YR+ +EI K +PI+ K ++ +E E K E RK V +A++ + P L+ D+Y P +
Sbjct: 41 DNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMTEGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHM-YTK---NFYGGNGIVGAQQPLGAGVALAMKYREQKNVC-VTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGMGTTAERSSASTEYYTRGDYVPG---------IWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEALKIATSDGVLPPEALYADIYHNTPAQ 369
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Celegans
Match: pdha-1 (Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P52899]) HSP 1 Score: 134.42 bits (337), Expect = 1.234e-34 Identity = 105/343 (30.61%), Postives = 161/343 (46.94%), Query Frame = 3
Query: 279 DNDPNIS----KETLIEMFKKMTLLNIFDRIMYDSQRQGRI-SFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGN--KNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAI------STPTSEQY-RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPR 1262
DN PN S +E ++ ++ M ++ + + ++ +I F G+E +G A+ + D V YR G G T+ +L + G N GKG M + YT N + + +G Q AG A A K R Q +C V +GDGAA++G A N + D P++F C NNG+ + S+ ++E Y RGD + I VDG DI AV ATK A+ C + P+++E TYR HS SD +YR+ +EI K +PI+ K ++ +E E K E RK V +A++ + P L+ D+Y P +
Sbjct: 41 DNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMTEGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHM-YTK---NFYGGNGIVGAQQPLGAGVALAMKYREQKNVC-VTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGMGTTAERSSASTEYYTRGDYVPG---------IWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEALKIATSDGVLPPEALYADIYHNTPAQ 369
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Celegans
Match: pdha-1 (Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P52899]) HSP 1 Score: 134.42 bits (337), Expect = 1.234e-34 Identity = 105/343 (30.61%), Postives = 161/343 (46.94%), Query Frame = 3
Query: 279 DNDPNIS----KETLIEMFKKMTLLNIFDRIMYDSQRQGRI-SFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGN--KNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAI------STPTSEQY-RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPR 1262
DN PN S +E ++ ++ M ++ + + ++ +I F G+E +G A+ + D V YR G G T+ +L + G N GKG M + YT N + + +G Q AG A A K R Q +C V +GDGAA++G A N + D P++F C NNG+ + S+ ++E Y RGD + I VDG DI AV ATK A+ C + P+++E TYR HS SD +YR+ +EI K +PI+ K ++ +E E K E RK V +A++ + P L+ D+Y P +
Sbjct: 41 DNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMTEGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHM-YTK---NFYGGNGIVGAQQPLGAGVALAMKYREQKNVC-VTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGMGTTAERSSASTEYYTRGDYVPG---------IWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEALKIATSDGVLPPEALYADIYHNTPAQ 369
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Fly
Match: CG8199 (gene:FBgn0037709 transcript:FBtr0082067) HSP 1 Score: 458.759 bits (1179), Expect = 7.906e-159 Identity = 213/399 (53.38%), Postives = 285/399 (71.43%), Query Frame = 3
Query: 132 FSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRAS-GYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
FSS S D FPG+++ + + L + P D I +YRV++++G I + DP + +E + +MF+ M LLN D+I+Y+SQRQGRISFYMTNFGEE + +GSA AL+ DL++GQYREAGV +WRG+ I+ ++QCYGN +D G+G+QMPVHY +++ N +ISSPL TQ+ A GAAYA K R N C VCYFG+GAASEGDAHAA NF++TL CP I FCRNNG+AISTP+ EQY+GDGIA R GYG+ IRVDG D+FAVYNA KAAR + EN+PV+ EA+ YRVG HSTSDDS AYR +EI W+ ++PIS+LK Y++++GW+ E E + + RK V+K I +EK PN E+FE VY +MP L +Q S+ + +K+ +P
Sbjct: 35 FSSKPSEDYANFPGAKAPFVSKLNLIQPEDYAPIPIYRVMDQDGYIADETQDPQLGREVVEKMFRDMVLLNTMDKILYESQRQGRISFYMTNFGEEASHIGSAAALEMRDLIYGQYREAGVLVWRGFRIDQFIDQCYGNTDDLGRGKQMPVHYGSRELNFVTISSPLSTQMPQAVGAAYAMKLRPNNDACVVCYFGEGAASEGDAHAAFNFAATLGCPAILFCRNNGFAISTPSHEQYKGDGIAGRGPMGYGITTIRVDGTDVFAVYNAMKAAREYVLKENKPVVFEALAYRVGHHSTSDDSTAYRPAEEIEIWNSVEHPISKLKRYMVHKGWFDETVENEYVKDIRKKVLKQIAVSEKKLKPNWREMFEGVYAEMPDHLIEQRSELEKHIEAHKEHYP 433
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Fly
Match: Pdha (gene:FBgn0028325 transcript:FBtr0070710) HSP 1 Score: 110.923 bits (276), Expect = 1.012e-26 Identity = 84/286 (29.37%), Postives = 131/286 (45.80%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY-DKMPPRL 1265
G+E +G A+ D + YR G G + G+L + G + +G+ +H N + + +G Q+ AG A K NG + +GDGAA++G A N + P+IF C NN Y + T + +R G + I VDG D+ AV +AT+ A N VN + P+++E TYR HS SD +YR+ +EI + +PI+ K + G + E K + RK V +A + A L+ DVY + + P+L
Sbjct: 29 GQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAP--NFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTR--GDALPGIWVDGMDVLAVRSATEFAINY-VNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKL 309
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Fly
Match: Pdha (gene:FBgn0028325 transcript:FBtr0070708) HSP 1 Score: 111.309 bits (277), Expect = 1.918e-26 Identity = 84/286 (29.37%), Postives = 131/286 (45.80%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY-DKMPPRL 1265
G+E +G A+ D + YR G G + G+L + G + +G+ +H N + + +G Q+ AG A K NG + +GDGAA++G A N + P+IF C NN Y + T + +R G + I VDG D+ AV +AT+ A N VN + P+++E TYR HS SD +YR+ +EI + +PI+ K + G + E K + RK V +A + A L+ DVY + + P+L
Sbjct: 100 GQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAP--NFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTR--GDALPGIWVDGMDVLAVRSATEFAINY-VNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKL 380
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Fly
Match: Pdha (gene:FBgn0028325 transcript:FBtr0070709) HSP 1 Score: 111.309 bits (277), Expect = 1.918e-26 Identity = 84/286 (29.37%), Postives = 131/286 (45.80%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY-DKMPPRL 1265
G+E +G A+ D + YR G G + G+L + G + +G+ +H N + + +G Q+ AG A K NG + +GDGAA++G A N + P+IF C NN Y + T + +R G + I VDG D+ AV +AT+ A N VN + P+++E TYR HS SD +YR+ +EI + +PI+ K + G + E K + RK V +A + A L+ DVY + + P+L
Sbjct: 100 GQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAP--NFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTR--GDALPGIWVDGMDVLAVRSATEFAINY-VNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKL 380
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Fly
Match: Pdha (gene:FBgn0028325 transcript:FBtr0070711) HSP 1 Score: 111.694 bits (278), Expect = 2.851e-26 Identity = 84/286 (29.37%), Postives = 131/286 (45.80%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY-DKMPPRL 1265
G+E +G A+ D + YR G G + G+L + G + +G+ +H N + + +G Q+ AG A K NG + +GDGAA++G A N + P+IF C NN Y + T + +R G + I VDG D+ AV +AT+ A N VN + P+++E TYR HS SD +YR+ +EI + +PI+ K + G + E K + RK V +A + A L+ DVY + + P+L
Sbjct: 144 GQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVLAELTGVQGGCARGKGGSMHMYAP--NFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTR--GDALPGIWVDGMDVLAVRSATEFAINY-VNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPKL 424
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Zebrafish
Match: bckdha (branched chain keto acid dehydrogenase E1 subunit alpha [Source:ZFIN;Acc:ZDB-GENE-050522-376]) HSP 1 Score: 534.643 bits (1376), Expect = 0.000e+0 Identity = 241/392 (61.48%), Postives = 304/392 (77.55%), Query Frame = 3
Query: 147 SIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
S + PQFPG+ +E+ HL+F+ P I GI VYRV++R+GQI+ DP +SKET++ ++KMTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD +DLVFGQYREAGV ++RG+ ++ + QCY N +D GKGRQMPVHY +KD N +ISSPL TQ+ AAGAAYA KR +CYFG+GAASEGDAHA NFS+TL+CP+IFFCRNNGYAISTPT+EQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+ + WW E EE+ WR ++RKLV++A E+ E+ PNP +F DVYD+M P + KQ + + + K+ +P
Sbjct: 49 SDEKPQFPGASAEFIDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPQLSKETVLNFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHIGSAAALDPSDLVFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGSKDLNFVTISSPLATQIPQAAGAAYAVKRENANRVVICYFGEGAASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGLMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFERAERRLKPNPDLMFTDVYDEMVPHIAKQKDSMWRHVQQYKEHYP 440
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Zebrafish
Match: bckdha (branched chain keto acid dehydrogenase E1 subunit alpha [Source:ZFIN;Acc:ZDB-GENE-050522-376]) HSP 1 Score: 534.643 bits (1376), Expect = 0.000e+0 Identity = 241/392 (61.48%), Postives = 304/392 (77.55%), Query Frame = 3
Query: 147 SIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
S + PQFPG+ +E+ HL+F+ P I GI VYRV++R+GQI+ DP +SKET++ ++KMTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD +DLVFGQYREAGV ++RG+ ++ + QCY N +D GKGRQMPVHY +KD N +ISSPL TQ+ AAGAAYA KR +CYFG+GAASEGDAHA NFS+TL+CP+IFFCRNNGYAISTPT+EQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+ + WW E EE+ WR ++RKLV++A E+ E+ PNP +F DVYD+M P + KQ + + + K+ +P
Sbjct: 49 SDEKPQFPGASAEFIDHLEFIQPNVISGIPVYRVMDRQGQIINPSEDPQLSKETVLNFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHIGSAAALDPSDLVFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGSKDLNFVTISSPLATQIPQAAGAAYAVKRENANRVVICYFGEGAASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGLMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFERAERRLKPNPDLMFTDVYDEMVPHIAKQKDSMWRHVQQYKEHYP 440
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Zebrafish
Match: pdha1a (pyruvate dehydrogenase E1 alpha 1 subunit a [Source:ZFIN;Acc:ZDB-GENE-040426-2719]) HSP 1 Score: 129.028 bits (323), Expect = 1.706e-32 Identity = 95/295 (32.20%), Postives = 137/295 (46.44%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKM----PP 1259
G+E +G ++ +D + YR G L RG T+ ++ + G + KG+ +H K + + + +G Q+ AG A A K + +N LC VC +GDGAA++G N +S P IF C NN Y + T S Y RGD I +RVDG D+ V ATK A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK +L+ S E K E R K IE + A +P ED+ + + PP
Sbjct: 99 GQEACAVGIEAGINLSDHLITAYRAHGYTLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--HFYGGNGIVGAQVPLGAGVALACKYQGKNELC-VCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISLLKDRMLSNNMASVEELKEIDVEVR----KEIEDAAQFATTDPEPPLEDLCNHIFYNDPP 377
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Zebrafish
Match: pdha1a (pyruvate dehydrogenase E1 alpha 1 subunit a [Source:ZFIN;Acc:ZDB-GENE-040426-2719]) HSP 1 Score: 129.028 bits (323), Expect = 1.706e-32 Identity = 95/295 (32.20%), Postives = 137/295 (46.44%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKM----PP 1259
G+E +G ++ +D + YR G L RG T+ ++ + G + KG+ +H K + + + +G Q+ AG A A K + +N LC VC +GDGAA++G N +S P IF C NN Y + T S Y RGD I +RVDG D+ V ATK A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK +L+ S E K E R K IE + A +P ED+ + + PP
Sbjct: 99 GQEACAVGIEAGINLSDHLITAYRAHGYTLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--HFYGGNGIVGAQVPLGAGVALACKYQGKNELC-VCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISLLKDRMLSNNMASVEELKEIDVEVR----KEIEDAAQFATTDPEPPLEDLCNHIFYNDPP 377
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Zebrafish
Match: pdha1a (pyruvate dehydrogenase E1 alpha 1 subunit a [Source:ZFIN;Acc:ZDB-GENE-040426-2719]) HSP 1 Score: 129.028 bits (323), Expect = 1.880e-32 Identity = 95/295 (32.20%), Postives = 137/295 (46.44%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKM----PP 1259
G+E +G ++ +D + YR G L RG T+ ++ + G + KG+ +H K + + + +G Q+ AG A A K + +N LC VC +GDGAA++G N +S P IF C NN Y + T S Y RGD I +RVDG D+ V ATK A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK +L+ S E K E R K IE + A +P ED+ + + PP
Sbjct: 116 GQEACAVGIEAGINLSDHLITAYRAHGYTLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--HFYGGNGIVGAQVPLGAGVALACKYQGKNELC-VCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISLLKDRMLSNNMASVEELKEIDVEVR----KEIEDAAQFATTDPEPPLEDLCNHIFYNDPP 394
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Xenopus
Match: h6pd (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [Source:Xenbase;Acc:XB-GENE-988586]) HSP 1 Score: 523.857 bits (1348), Expect = 0.000e+0 Identity = 241/405 (59.51%), Postives = 310/405 (76.54%), Query Frame = 3
Query: 60 IIEKIMHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
+ + ++ +F FL+T R I +F+S + PQFPG+ +++ L+F+ P I GI +YRV++R+GQI+ DP I KE +++ + MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ DLVFGQYREAGV ++RGY ++ + QCYGN +D GKG+QMPVHY KD N +ISSPL TQ+ A GAAY+FKR +CYFG+GAASEGDAHAA NFS+TL+CP++FFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+L++GWW E +EKIWR ++RK+V++A E+ E+ P +F DVY +MP +L KQ
Sbjct: 3 LFKYLLSSFYLFLYTRR--IRAVEFTSLE--EKPQFPGASADFVDSLEFIQPNVISGIPIYRVMDRQGQIINPSEDPKIPKEKVLKFYHTMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALNDTDLVFGQYREAGVLMYRGYPLDLFMAQCYGNASDPGKGKQMPVHYGCKDLNFVTISSPLATQIPQAVGAAYSFKRENADRAVICYFGEGAASEGDAHAAFNFSATLECPVLFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLHKGWWDEEQEKIWRKKSRKMVMEAFEEAERKHKPKVEHMFSDVYSEMPAQLRKQ 403
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Xenopus
Match: h6pd (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [Source:Xenbase;Acc:XB-GENE-988586]) HSP 1 Score: 520.39 bits (1339), Expect = 0.000e+0 Identity = 236/384 (61.46%), Postives = 300/384 (78.12%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q++F+S + PQFPG+ +++ L+F+ P I GI +YRV++R+GQI+ DP I KE +++ + MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ DLVFGQYREAGV ++RGY ++ + QCYGN +D GKG+QMPVHY KD N +ISSPL TQ+ A GAAY+FKR +CYFG+GAASEGDAHAA NFS+TL+CP++FFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+L++GWW E +EKIWR ++RK+V++A E+ E+ P +F DVY +MP +L KQ
Sbjct: 30 QSEFTSLE--EKPQFPGASADFVDSLEFIQPNVISGIPIYRVMDRQGQIINPSEDPKIPKEKVLKFYHTMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALNDTDLVFGQYREAGVLMYRGYPLDLFMAQCYGNASDPGKGKQMPVHYGCKDLNFVTISSPLATQIPQAVGAAYSFKRENADRAVICYFGEGAASEGDAHAAFNFSATLECPVLFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLHKGWWDEEQEKIWRKKSRKMVMEAFEEAERKHKPKVEHMFSDVYSEMPAQLRKQ 411
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Xenopus
Match: h6pd (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [Source:Xenbase;Acc:XB-GENE-988586]) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 236/384 (61.46%), Postives = 300/384 (78.12%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q++F+S + PQFPG+ +++ L+F+ P I GI +YRV++R+GQI+ DP I KE +++ + MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ DLVFGQYREAGV ++RGY ++ + QCYGN +D GKG+QMPVHY KD N +ISSPL TQ+ A GAAY+FKR +CYFG+GAASEGDAHAA NFS+TL+CP++FFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+L++GWW E +EKIWR ++RK+V++A E+ E+ P +F DVY +MP +L KQ
Sbjct: 9 QSEFTSLE--EKPQFPGASADFVDSLEFIQPNVISGIPIYRVMDRQGQIINPSEDPKIPKEKVLKFYHTMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALNDTDLVFGQYREAGVLMYRGYPLDLFMAQCYGNASDPGKGKQMPVHYGCKDLNFVTISSPLATQIPQAVGAAYSFKRENADRAVICYFGEGAASEGDAHAAFNFSATLECPVLFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLHKGWWDEEQEKIWRKKSRKMVMEAFEEAERKHKPKVEHMFSDVYSEMPAQLRKQ 390
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Xenopus
Match: h6pd (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [Source:Xenbase;Acc:XB-GENE-988586]) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 238/393 (60.56%), Postives = 303/393 (77.10%), Query Frame = 3
Query: 96 LFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
LF + I ++F+S + PQFPG+ +++ L+F+ P I GI +YRV++R+GQI+ DP I KE +++ + MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ DLVFGQYREAGV ++RGY ++ + QCYGN +D GKG+QMPVHY KD N +ISSPL TQ+ A GAAY+FKR +CYFG+GAASEGDAHAA NFS+TL+CP++FFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+L++GWW E +EKIWR ++RK+V++A E+ E+ P +F DVY +MP +L KQ
Sbjct: 8 LFFRKLYITGSEFTSLE--EKPQFPGASADFVDSLEFIQPNVISGIPIYRVMDRQGQIINPSEDPKIPKEKVLKFYHTMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALNDTDLVFGQYREAGVLMYRGYPLDLFMAQCYGNASDPGKGKQMPVHYGCKDLNFVTISSPLATQIPQAVGAAYSFKRENADRAVICYFGEGAASEGDAHAAFNFSATLECPVLFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLHKGWWDEEQEKIWRKKSRKMVMEAFEEAERKHKPKVEHMFSDVYSEMPAQLRKQ 398
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Xenopus
Match: h6pd (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [Source:Xenbase;Acc:XB-GENE-988586]) HSP 1 Score: 519.235 bits (1336), Expect = 0.000e+0 Identity = 236/384 (61.46%), Postives = 300/384 (78.12%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q++F+S + PQFPG+ +++ L+F+ P I GI +YRV++R+GQI+ DP I KE +++ + MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ DLVFGQYREAGV ++RGY ++ + QCYGN +D GKG+QMPVHY KD N +ISSPL TQ+ A GAAY+FKR +CYFG+GAASEGDAHAA NFS+TL+CP++FFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+L++GWW E +EKIWR ++RK+V++A E+ E+ P +F DVY +MP +L KQ
Sbjct: 14 QSEFTSLE--EKPQFPGASADFVDSLEFIQPNVISGIPIYRVMDRQGQIINPSEDPKIPKEKVLKFYHTMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALNDTDLVFGQYREAGVLMYRGYPLDLFMAQCYGNASDPGKGKQMPVHYGCKDLNFVTISSPLATQIPQAVGAAYSFKRENADRAVICYFGEGAASEGDAHAAFNFSATLECPVLFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLHKGWWDEEQEKIWRKKSRKMVMEAFEEAERKHKPKVEHMFSDVYSEMPAQLRKQ 395
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Mouse
Match: Bckdha (branched chain ketoacid dehydrogenase E1, alpha polypeptide [Source:MGI Symbol;Acc:MGI:107701]) HSP 1 Score: 508.449 bits (1308), Expect = 3.316e-178 Identity = 235/374 (62.83%), Postives = 294/374 (78.61%), Query Frame = 3
Query: 153 DTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ +E +++ ++ MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL++ DLVFGQYREAGV ++R Y +E ++QCYGN ND GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+ YLLNQGWW E +EK WR ++RK V++A E+ E+ PNP LF DVY +MP +L +Q
Sbjct: 51 DKPQFPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKFYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLELFMSQCYGNVNDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRIVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVYQEMPAQLRRQ 424
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Mouse
Match: Bckdha (branched chain ketoacid dehydrogenase E1, alpha polypeptide [Source:MGI Symbol;Acc:MGI:107701]) HSP 1 Score: 138.658 bits (348), Expect = 2.981e-39 Identity = 63/82 (76.83%), Postives = 71/82 (86.59%), Query Frame = 3
Query: 753 MNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTY 998
NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTY
Sbjct: 1 FNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTY 82
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Mouse
Match: Pdha1 (pyruvate dehydrogenase E1 alpha 1 [Source:MGI Symbol;Acc:MGI:97532]) HSP 1 Score: 122.865 bits (307), Expect = 2.409e-30 Identity = 90/290 (31.03%), Postives = 126/290 (43.45%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPP 1259
G+E +G ++ D + YR G RG + +L + G + KG+ +H K N + + +G Q+ AG A A K N + +GDGAA++G A N ++ P IF C NN Y + T S Y RGD I +RVDG DI V ATK A C + P+L+E TYR HS SD ++YR+ +EI +PI LK ++N S E K E RK + A + P EL +Y PP
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPG---------LRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPP 374
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Mouse
Match: Pdha2 (pyruvate dehydrogenase E1 alpha 2 [Source:MGI Symbol;Acc:MGI:97533]) HSP 1 Score: 115.931 bits (289), Expect = 6.834e-28 Identity = 96/356 (26.97%), Postives = 158/356 (44.38%), Query Frame = 3
Query: 219 DIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNF-----GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDV----YDKMPP 1259
DI+ +YR+ ++ P + T E K + + R+ + + + F + F G+E +G ++ D V YR G RG +++ +L + G K KG+ +H K N + + +G Q+ AG A+A K +NG + +GDGAA++G A N S+ P +F C NN Y + T S + G+ + +RV+G DI V ATK A + C + P+++E TYR HS SD ++YRS +E+ +PI L+ +++ + E K E V K +E + A +P ED+ Y + PP
Sbjct: 38 DIKKCDLYRL---------EEGPPTSTVLTRAEALKYYRTMQVIRRMELKADQLYKQKF-IRGFCHLCDGQEACCVGLEAGINPTDHVITSYRAHGFCYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYGK--NFYGGNGIVGAQVPLGAGVAFACKYLKNGQVCLALYGDGAANQGQVFEAYNMSALWKLPCVFICENNLYGMGT--SNERSAASTDYHKKGFIIPGLRVNGMDILCVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGISYRSREEVHNVRSKSDPIMLLRERIISNNLSNIEELK----EIDADVKKEVEDAAQFATTDPEPAVEDIANYLYHQDPP 375
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. UniProt/SwissProt
Match: sp|Q8HXY4|ODBA_MACFA (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Macaca fascicularis OX=9541 GN=BCKDHA PE=2 SV=1) HSP 1 Score: 514.612 bits (1324), Expect = 7.778e-180 Identity = 243/384 (63.28%), Postives = 299/384 (77.86%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HYLL+QGWW E +EK WR ++RK V+KA E+ E+ PNP LF DVY +MP +L KQ
Sbjct: 42 QQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMKAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQ 423
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. UniProt/SwissProt
Match: sp|A5A6H9|ODBA_PANTR (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Pan troglodytes OX=9598 GN=BCKDHA PE=2 SV=1) HSP 1 Score: 512.686 bits (1319), Expect = 4.812e-179 Identity = 243/393 (61.83%), Postives = 302/393 (76.84%), Query Frame = 3
Query: 96 LFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
L S + Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+P+SRL+HYLL+QGWW E +EK WR ++RK V++A E+ E+ PNP LF DVY +MP +L KQ
Sbjct: 33 LARSHPRRQQQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPVSRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQ 423
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. UniProt/SwissProt
Match: sp|P12694|ODBA_HUMAN (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2) HSP 1 Score: 512.301 bits (1318), Expect = 8.213e-179 Identity = 241/384 (62.76%), Postives = 299/384 (77.86%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
Q +FSS D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ KE +++++K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HYLL+QGWW E +EK WR ++R+ V++A E+ E+ PNP LF DVY +MP +L KQ
Sbjct: 42 QQQFSS--LDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQLRKQ 423
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. UniProt/SwissProt
Match: sp|P50136|ODBA_MOUSE (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Bckdha PE=1 SV=1) HSP 1 Score: 507.294 bits (1305), Expect = 6.624e-177 Identity = 234/374 (62.57%), Postives = 294/374 (78.61%), Query Frame = 3
Query: 153 DTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ +E +++ ++ MTLLN DRI+Y+SQR+GRISFYMTN+GEEG +GSA AL++ DLVFGQYREAGV ++R Y +E ++QCYGN ND GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+ YLLNQGWW E +EK WR ++RK V++A E+ E+ PNP LF DVY +MP +L +Q
Sbjct: 47 DKPQFPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKFYRSMTLLNTMDRILYESQREGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLELFMSQCYGNVNDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRIVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIKSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVYQEMPAQLRRQ 420
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. UniProt/SwissProt
Match: sp|P11960|ODBA_RAT (2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (Fragment) OS=Rattus norvegicus OX=10116 GN=Bckdha PE=1 SV=1) HSP 1 Score: 506.523 bits (1303), Expect = 1.034e-176 Identity = 234/374 (62.57%), Postives = 294/374 (78.61%), Query Frame = 3
Query: 153 DTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQ 1274
D PQFPG+ +E+ L+F+ P I GI +YRV++R+GQI+ DP++ +E ++++++ MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL++ DLVFGQYREAGV ++R Y +E + QCYGN +D GKGRQMPVHY K+ + +ISSPL TQ+ A GAAYA KR +CYFG+GAASEGDAHA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R GYG+ IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+ YLLNQGWW E +EK WR ++RK V++A E+ E+ PNP LF DVY +MP +L +Q
Sbjct: 46 DKPQFPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKLYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLELFMAQCYGNVSDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANQIVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVYQEMPAQLRRQ 419
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. TrEMBL
Match: V4AHL2 (2-oxoisovalerate dehydrogenase subunit alpha OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_202459 PE=3 SV=1) HSP 1 Score: 552.362 bits (1422), Expect = 0.000e+0 Identity = 245/393 (62.34%), Postives = 315/393 (80.15%), Query Frame = 3
Query: 153 DTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPTAY 1331
+ P+FPGS+SE+ + LKF+ P ++GI VYR L R+G+I+ DP + ET+I+M+K MTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD+ D+VFGQYREAGV +WRG+T++ ++QCYGN+ND GKGRQMPVHY +K+ N +ISSPL TQ+ AAGAAYA+KR +NGLC +CYFG+GAASEGDAHAA NF++ LDCP+IFFCRNNGYAISTP +QYRGDGIASR GYGM +RVDGND+FAVYNA K+AR++CV +NRPVLIEAMTYR+G HSTSDDS AYRSVDE+S+WDK DNPISRL++Y+ N +W E +EK W+ +ARKLV+K+ + E PNP E+F DVYD +P L +Q ++ + + + K+ +P +
Sbjct: 48 ERPEFPGSKSEFISKLKFIDPDKVDGIPVYRALGRDGKILEDSEDPKLDSETVIKMYKDMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHIGSAAALDQKDMVFGQYREAGVLMWRGFTLDQFMDQCYGNENDIGKGRQMPVHYGSKEMNFMTISSPLATQMPQAAGAAYAYKRAKNGLCVICYFGEGAASEGDAHAAFNFAAVLDCPVIFFCRNNGYAISTPVKDQYRGDGIASRGIGYGMPTVRVDGNDVFAVYNAVKSARDMCVAQNRPVLIEAMTYRIGHHSTSDDSSAYRSVDEVSYWDKQDNPISRLRNYMTNNNFWDEEKEKAWKLKARKLVMKSFAEAENRKRPNPEEMFNDVYDILPKHLEEQKNEMKAHVKQYKENYPLEH 440
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. TrEMBL
Match: A0A2T7NW70 (2-oxoisovalerate dehydrogenase subunit alpha OS=Pomacea canaliculata OX=400727 GN=C0Q70_13063 PE=3 SV=1) HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0 Identity = 245/420 (58.33%), Postives = 317/420 (75.48%), Query Frame = 3
Query: 63 IEKIMHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
++K+ H F + A++ D P+FPGSRS Y L+FL P EGI VYRVLNREG I+ + DP +S+ + +M+ MTLLN DR++Y+SQRQGRISFYMTN+GEEG +GSA ALD DL+FGQYREAGV +WRGYT++ +NQCYGN+ND GKGRQMPVHY ++D N +ISSPL TQ+ A+GAAYA K Q GL +C+FG+GAASEGDAHAA+NF++ LDCP+IFFCRNNGYAISTPT +QYRGDGIA+R GYG+ +RVDGND+FAVYNATKAAR++C+ +NRPVLIEAMTYR+G HSTSDDS AYRSVDE+S+WD+ DNPI+RL+H+++ Q WW++ E+ W+ E+RK+V+KA + E P+P +F DVY M P L +QM + ++K+ +P
Sbjct: 20 VQKVAACGIHHTFAQQGSQSTARYE-----DKPEFPGSRSRYVHKLEFLDPDSQEGIPVYRVLNREGTIIDESQDPKLSRAIVEKMYHDMTLLNTMDRVLYESQRQGRISFYMTNYGEEGTHVGSAAALDSKDLIFGQYREAGVLMWRGYTLDQFMNQCYGNQNDLGKGRQMPVHYGSRDLNFVTISSPLATQMPQASGAAYALKLQQKGLVAICFFGEGAASEGDAHAALNFAAVLDCPIIFFCRNNGYAISTPTKDQYRGDGIAARGRGYGIPTVRVDGNDVFAVYNATKAARDICLTQNRPVLIEAMTYRIGHHSTSDDSSAYRSVDEVSYWDQQDNPITRLRHFMVLQKWWNDDAEQNWKMESRKMVMKAFAEAEGRKKPSPDSMFHDVYTDMHPSLKEQMQAMKKHVTEHKEHYP 434
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. TrEMBL
Match: A0A3Q1FVC0 (2-oxoisovalerate dehydrogenase subunit alpha OS=Acanthochromis polyacanthus OX=80966 PE=3 SV=1) HSP 1 Score: 545.043 bits (1403), Expect = 0.000e+0 Identity = 254/436 (58.26%), Postives = 319/436 (73.17%), Query Frame = 3
Query: 15 LCFVYVNQLLKYTA*IIEKIMHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
LCF V Q K +H F + Q F S S++ PQFPG+ +E+ HL+F+ P I GI +YRV++R+G+I+ DP +SKET++ ++KMTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD NDLVFGQYREAGV ++RG+ ++ + QCY N +D GKGRQMPVHY ++D N +ISSPL TQL AAGAAYA KR +CYFG+GAASEGDAHA +NFS+TL+CP+IFFCRNNGYAISTPT+EQYRGDGIA+R GYGM IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+ +GWWSE +E+ WR ++RK V++A E+ EK PNP LF DVY +M P L KQ + + + K+ +P
Sbjct: 13 LCFHAVRQTAG------RKASRLLQHRTFRVTAVHQQQPFDS--SLEKPQFPGASAEFVDHLEFIQPNVISGIPIYRVMDRQGKIVNPSEDPQLSKETVLNFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDPNDLVFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGSRDLNFVTISSPLATQLPQAAGAAYALKRENENRAVICYFGEGAASEGDAHAGLNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMTARGWWSEDDERSWRKQSRKTVMEAFERAEKRLKPNPELLFTDVYQEMTPNLEKQRESLWRHVQQYKEHYP 440
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. TrEMBL
Match: C3ZXF5 (2-oxoisovalerate dehydrogenase subunit alpha OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_224333 PE=3 SV=1) HSP 1 Score: 544.658 bits (1402), Expect = 0.000e+0 Identity = 247/390 (63.33%), Postives = 305/390 (78.21%), Query Frame = 3
Query: 153 DTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
D PQFPGSRSE+T L+F+ P GI VYRVL+R+G+I+ D DP +SKE + +M+ KMTLLN DRI+Y+SQRQGRISFYMTN+GEE +GSA AL+ D+VFGQYREAGV ++RG+T++ +NQCYGN D G+GRQMPVHY +K+ N +ISSPLGTQ+ A+GAAYA KR+ LC +CYFGDGAASEGDAHAA NF++TL+CP+IFFCRNNGYAISTPTSEQYRGDGIA+R YGMA +RVDGND FAVYNA KAAR L VNENRPVLIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PI RL+HY++NQGWW +EK W +AR V++A ++ EK P P ELF D Y +M P L +Q + + + + +P
Sbjct: 18 DKPQFPGSRSEFTKKLEFITPDVYNGIPVYRVLDRQGKIIEADQDPKLSKEAVYDMYHKMTLLNTMDRILYESQRQGRISFYMTNYGEEATHMGSAAALNPGDVVFGQYREAGVLMYRGFTLDQFMNQCYGNAEDAGRGRQMPVHYGSKELNFVTISSPLGTQMPQASGAAYALKRSGKRLCVICYFGDGAASEGDAHAAFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPSYGMATLRVDGNDAFAVYNAVKAARELAVNENRPVLIEAMTYRIGHHSTSDDSTAYRSVDEVNYWDKQDHPIGRLRHYMVNQGWWDMEKEKAWMKQARNEVMQAFQRAEKKKKPPPSELFYDTYREMLPHLQQQREQMRKHVAQYPENYP 407
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. TrEMBL
Match: A0A2C9JEY2 (2-oxoisovalerate dehydrogenase subunit alpha OS=Biomphalaria glabrata OX=6526 GN=106055402 PE=3 SV=1) HSP 1 Score: 544.658 bits (1402), Expect = 0.000e+0 Identity = 248/435 (57.01%), Postives = 327/435 (75.17%), Query Frame = 3
Query: 36 QLLKYTA*IIEKIMHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPTAYETP 1340
Q LK + II + + + + +R K F + +S++ I P FPGSRSE+ + L+F+ P + EGI VYR LN +G + DP + + T+++M+K MTLLN DR++YDSQRQGRISFYMTN+GEEG +GSA ALD DL++GQYREAGV +WRG+ ++ ++QCYGN D GKGRQMPVHY +++ N +ISS L TQ+ A+G+AYAFKR QNGLC +CYFG+GAASEGDAHAA NF++ L+CP+IFFCRNNGYAISTPT +QYRGDGIASRA+GYGM +RVDGND+FAVYNATK AR +C++++RPVLIEAMTYR+G HSTSDDS AYRSVDE+S WDK DNPISR + Y++NQG W + +E+ W+ ++RK+V+KA E P LFEDVYD+MP L +QM+ + + + K+ +P + P
Sbjct: 8 QALKISNSIIPQYLQSSSALI--NRVKCF-SYYSTSAEIGKPNFPGSRSEFISKLEFIDPDNAEGIPVYRALNADGNFIDASQDPKLDESTVLKMYKDMTLLNTMDRVLYDSQRQGRISFYMTNYGEEGTHIGSAAALDPKDLIYGQYREAGVLMWRGFPLQQFMHQCYGNAKDIGKGRQMPVHYGSRELNFVTISSTLATQMPQASGSAYAFKRKQNGLCVICYFGEGAASEGDAHAAFNFAAVLNCPIIFFCRNNGYAISTPTKDQYRGDGIASRAAGYGMLSVRVDGNDVFAVYNATKKAREMCISQSRPVLIEAMTYRIGHHSTSDDSSAYRSVDEVSHWDKTDNPISRFRRYMMNQGLWDDDKEQQWKLDSRKMVMKAFAAAESEKRGRPESLFEDVYDEMPDHLKQQMNSMKNHVKQYKEHYPLEHYQP 439
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Cavefish
Match: bckdha (branched chain keto acid dehydrogenase E1 subunit alpha [Source:NCBI gene;Acc:103041479]) HSP 1 Score: 540.806 bits (1392), Expect = 0.000e+0 Identity = 247/408 (60.54%), Postives = 311/408 (76.23%), Query Frame = 3
Query: 99 FTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
F ++ +FQ F S S + PQFPG+ +E+ HL+F+ P I GI +YRV++R+GQI+ DPN+SKET++ ++KMTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++RG+ ++ + QCY N +D GKGRQMPVHY KD N +ISSPL TQ+ AAGAAYA KR +CYFG+GAASEGDAHA NFS+TL+CP+IFFCRNNGYAISTPT+EQYRGDGIA+R GYGM IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+ + WW E EE+ WR ++RKLV++A E+ E+ P+P +F DVYD+M P L KQ + + + K+ +P
Sbjct: 35 FRTQGALFQQPFDS--SAEKPQFPGASAEFVDHLEFIQPNVISGIPIYRVMDRQGQIINPSEDPNLSKETVLNFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDPTDLVFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGCKDLNFVTISSPLATQIPQAAGAAYAVKRENANRAVICYFGEGAASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFERAERRLKPHPDLMFTDVYDQMTPGLEKQKEAMWRHVQQYKEHYP 440
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Cavefish
Match: bckdha (branched chain keto acid dehydrogenase E1 subunit alpha [Source:NCBI gene;Acc:103041479]) HSP 1 Score: 476.863 bits (1226), Expect = 6.926e-167 Identity = 218/344 (63.37%), Postives = 269/344 (78.20%), Query Frame = 3
Query: 291 NISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFP 1322
++SKET++ ++KMTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA ALD DLVFGQYREAGV ++RG+ ++ + QCY N +D GKGRQMPVHY KD N +ISSPL TQ+ AAGAAYA KR +CYFG+GAASEGDAHA NFS+TL+CP+IFFCRNNGYAISTPT+EQYRGDGIA+R GYGM IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+ + WW E EE+ WR ++RKLV++A E+ E+ P+P +F DVYD+M P L KQ + + + K+ +P
Sbjct: 26 SLSKETVLNFYQKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDPTDLVFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGCKDLNFVTISSPLATQIPQAAGAAYAVKRENANRAVICYFGEGAASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFERAERRLKPHPDLMFTDVYDQMTPGLEKQKEAMWRHVQQYKEHYP 369
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Cavefish
Match: pdha1a (pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like [Source:NCBI gene;Acc:103026590]) HSP 1 Score: 132.88 bits (333), Expect = 6.175e-34 Identity = 97/295 (32.88%), Postives = 136/295 (46.10%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKM----PP 1259
G+E +G ++ D + YR G L RG T+ ++ + G + KG+ +H K N + + +G Q+ AG A A K + +N LC VC +GDGAA++G N +S P IF C NN Y + T S Y RGD I +RVDG D+ V ATK A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK +LN S E K E R K IE + A +P ED+ + + PP
Sbjct: 99 GQEACAVGIEAGINLTDHLITAYRAHGYTLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--NFYGGNGIVGAQVPLGAGVALACKYQGKNELC-VCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISMLKDRMLNNNMASVEELKEIDVEVR----KEIEDAAQFATTDPEPPLEDLCNHIFCNEPP 377
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Cavefish
Match: pdha1a (pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like [Source:NCBI gene;Acc:103026590]) HSP 1 Score: 132.88 bits (333), Expect = 6.825e-34 Identity = 97/295 (32.88%), Postives = 136/295 (46.10%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKM----PP 1259
G+E +G ++ D + YR G L RG T+ ++ + G + KG+ +H K N + + +G Q+ AG A A K + +N LC VC +GDGAA++G N +S P IF C NN Y + T S Y RGD I +RVDG D+ V ATK A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK +LN S E K E R K IE + A +P ED+ + + PP
Sbjct: 106 GQEACAVGIEAGINLTDHLITAYRAHGYTLTRGGTVREIMAELTGRRGGIAKGKGGSMHMYTK--NFYGGNGIVGAQVPLGAGVALACKYQGKNELC-VCLYGDGAANQGQIFETYNMASLWKLPCIFICENNKYGMGTSVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATKFAAEHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISMLKDRMLNNNMASVEELKEIDVEVR----KEIEDAAQFATTDPEPPLEDLCNHIFCNEPP 384
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Cavefish
Match: pdha1b (pyruvate dehydrogenase E1 alpha 1 subunit b [Source:ZFIN;Acc:ZDB-GENE-040718-96]) HSP 1 Score: 105.531 bits (262), Expect = 1.605e-24 Identity = 90/294 (30.61%), Postives = 130/294 (44.22%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKM----PP 1259
G+E +G ++ D + YR G RG +++ +L + G K KG+ +H K + + + +G Q+ AG A A + N V +GDGAA++G A N +S P IF C NN Y + T S Y RGD I +RVDG D+ V ATK A + C + P+L+E TYR HS SD L + EI +PIS LK ++N S E K E R K IE+ + A +P +D+ + + PP
Sbjct: 81 GQEACAMGIEAGINPTDHLITAYRAHGYTYTRGVSVKEILAELTGRKGGVAKGKGGSMHMYAK--HFYGGNGIVGAQVPLGAGVALACQYKGNNEVCVTLYGDGAANQGQIFEAFNMASLWKLPCIFICENNKYGMGTSVERASASTDYYKRGDFIPG---------LRVDGMDVLCVREATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGLP--NTVEIQEVRSKSDPISMLKDRMINNNMASLEEIKEIDAEVR----KEIEEAAQFATSDPEPPLDDLCNHIFYNEPP 357
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Sea Lamprey
Match: bckdha (branched chain keto acid dehydrogenase E1 subunit alpha [Source:ZFIN;Acc:ZDB-GENE-050522-376]) HSP 1 Score: 516.924 bits (1330), Expect = 0.000e+0 Identity = 237/382 (62.04%), Postives = 301/382 (78.80%), Query Frame = 3
Query: 153 DTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQL----LHAA-GAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSK 1283
D P FPG+ +EY+ ++F+ P I GI VYRV++R+GQI+ DP + KET+++M+KKMTLLN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ +DLVFGQYREAGV +WR + ++ ++QCYGN +D GKGRQMPVHY + + N +ISSPL TQ+ HAA GAAYA+KR N +CYFG+GAASEGDAHA NFS+TL+CP+IFFCRNNGYAISTPT EQYRGDGIA+R GYG+ IRVDGND+FAVYNAT+ AR V+EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL++Y+L + W++ EK WR ++RKLV++A EK EK P+P ELF DVY +M P + +QM +
Sbjct: 4 DKPLFPGASAEYSDTMEFIQPNVIAGIPVYRVMDRQGQIINPKEDPKLDKETVLKMYKKMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHMGSAAALEPHDLVFGQYREAGVLMWRDFPLDMFMSQCYGNVDDPGKGRQMPVHYGSNELNFVTISSPLATQIPQARTHAAVGAAYAYKRANNDRVVICYFGEGAASEGDAHAGFNFSATLECPVIFFCRNNGYAISTPTDEQYRGDGIAARGPGYGILSIRVDGNDVFAVYNATREARRRAVSENQPTLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRNYMLRESMWNDSLEKDWRKQSRKLVLEAFEKAEKRLKPSPSELFHDVYKEMTPHIQRQMDE 385
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Yeast
Match: PDA1 (E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex; catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose; PDH complex is concentrated in spots within the mitochondrial matrix, often near the ERMES complex and near peroxisomes [Source:SGD;Acc:S000000980]) HSP 1 Score: 153.68 bits (387), Expect = 3.249e-42 Identity = 106/358 (29.61%), Postives = 172/358 (48.04%), Query Frame = 3
Query: 213 PTDIEGISVYRVLNREGQIMGQDNDP-----NISKETLIEMFKKMTLLNIFDRIMYDSQRQGRI-SFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKN--DFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPME----LFEDVYDK 1250
P DIEG ++ E +P SK TL++M+K M ++ + + +I F + G+E +G A+ K D + YR G RG +++ +L + G + +GKG M ++ + + +G Q+ AG A+A + C+ +GDGA+++G + N + + P++F C NN Y + T S R G + ++V+G DI AVY A+K A++ C++ P+++E TYR G HS SD YR+ DEI ++PI+ LK +L++ G +E E K + ARK V + +E + A P P LFEDVY K
Sbjct: 44 PEDIEGSDTVQIELPESSFESYMLEPPDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLY----APGFYGGNGIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVFCCENNKYGMGTAASRSSAMTEYFKR--GQYIPGLKVNGMDILAVYQASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDKSARKYVDEQVELAD--AAPPPEAKLSILFEDVYVK 393
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Nematostella
Match: EDO43057 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZV6]) HSP 1 Score: 498.819 bits (1283), Expect = 5.901e-175 Identity = 230/407 (56.51%), Postives = 300/407 (73.71%), Query Frame = 3
Query: 111 SKIFQAKFSSNVSIDTPQFPGSRS-EYTTHLKFLFPTDIEGI-SVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPT 1325
++ + + N+ D P++PG+ + +T L+F+ P D +GI VYRV++R+G+I+ +DP + + T+++M+KKMTLLN DRI+Y+SQRQGRISFYMTN+GEE GSA AL+ DL+ GQYREAGV +WRG+T+ +NQCY N++D GKGRQMPVHY +K+ N +ISS L TQ+ A+GAAYA KR G C +CYFGDGAASEGDAH+A NF++TLD P+IFFCRNNGYAISTPT EQYRGDGIA R YGM IRVDGNDIFAVYN TK AR + VNENRPVL+EAMTYR+G HSTSDDS YRS+ E+++WDK D+PISRL++Y+ ++GWW + +E+ W+ EAR V++A EK P ELF DVY + P L +Q + + K +PT
Sbjct: 32 TRFISSDSTENIFKDKPRYPGAMNCSFTEKLEFVDPMDPQGIIPVYRVMDRQGKIIIDSHDPKLPEGTIVDMYKKMTLLNTMDRILYESQRQGRISFYMTNYGEEATHFGSAAALEMEDLIMGQYREAGVLMWRGFTLADFMNQCYANQHDAGKGRQMPVHYGSKELNFVTISSTLATQMPQASGAAYALKRQGKGNCVMCYFGDGAASEGDAHSAFNFAATLDAPVIFFCRNNGYAISTPTREQYRGDGIACRGRSYGMLAIRVDGNDIFAVYNVTKKAREIAVNENRPVLVEAMTYRIGHHSTSDDSSVYRSLKEVNYWDKEDHPISRLRYYMEDKGWWDQDQEQQWKKEARLQVMQAFADAEKALKPPVKELFLDVYKEFTPHLQEQYKECVDHVAKYPHEYPT 438
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Nematostella
Match: EDO33561 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRY1]) HSP 1 Score: 132.109 bits (331), Expect = 3.884e-34 Identity = 95/285 (33.33%), Postives = 135/285 (47.37%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAIST------PTSEQY-RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY 1244
G+E +G ++DKND V YR G RG + +L + G K +G+ +H + + + +G Q+ AG A A K NG + +GDGAA++G N + + P IF C NNGY + T T+E Y RGD I IRVDG D+ V ATK A + + P+L+E TYR HS SD +YRS DEI K +PI+ L+ LL+ G S + K EA+ + +A+E + P +LF VY
Sbjct: 99 GQEACCVGMEASIDKNDSVITAYRCHGWTYMRGRSAREVLCELTGRKTGCTQGKGGSMHMYGHE--YYGGNGIVGAQVPLGAGIALAHKLRGNGRICLTLYGDGAANQGQLFETYNMAKLWNLPCIFICENNGYGMGTSVERAAATTEYYSRGDYIPG---------IRVDGMDVLTVREATKWAVDYARSGKGPILMELKTYRYYGHSMSDPGTSYRSRDEIQSVRKTRDPITGLREKLLDSGLASTDDIKKIEQEAKAEIDEAVECAKNDPEPPLDDLFMHVY 372
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Nematostella
Match: EDO47218 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMW9]) HSP 1 Score: 49.2914 bits (116), Expect = 3.062e-6 Identity = 41/127 (32.28%), Postives = 60/127 (47.24%), Query Frame = 3
Query: 630 LGTQLLHAAGAAYAFKR-NQNGLCTVCYFGDGAASEGDAHAAMNFSS--TLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYR 1001
LG L A G AY K ++ C GDG ++EG AM+F+S LD + F N S PT+ Q++ D RA +G I +DG+D+ AV A A + +P + A T++
Sbjct: 125 LGQGLSCACGMAYMGKHIDKASYRVFCLLGDGESAEGAVWEAMSFASFYKLDNLVAIFDVNR-LGQSQPTALQHKMDVYRQRAEAFGWNAIVIDGHDVEAVCRAFHEAE---ITTGKPTCLLAKTFK 247
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Medaka
Match: bckdha (branched chain keto acid dehydrogenase E1 subunit alpha [Source:NCBI gene;Acc:101166649]) HSP 1 Score: 527.709 bits (1358), Expect = 0.000e+0 Identity = 240/401 (59.85%), Postives = 305/401 (76.06%), Query Frame = 3
Query: 123 QAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPT 1325
Q F S S++ PQFPG+ +++ HL+F+ P I GI VYRV++R+G I+ DP +SKET++ ++KMT+LN DRI+Y+SQRQGRISFYMTN+GEEG +GSA AL+ D+VFGQYREAGV ++RG+ ++ + QCY N +D GKGRQMPVHY KD N +ISSPL TQ+ AAGAAYA KR +CYFG+GAASEGDAHA NFS+TL+CP+IFFCRNNGYAISTPT+EQYRGDGIA+R GYGM IRVDGND+FAVYNATK AR V EN+P LIEAMTYR+G HSTSDDS AYRSVDE+++WDK D+PISRL+HY+ +GWWSE +E+ WR ++RK V++A E+ E+ PNP LF DVY +M P L +Q + + + K+ +P
Sbjct: 46 QQPFDS--SLEKPQFPGASADFVDHLEFIQPNVISGIPVYRVMDRQGNIINPSQDPQLSKETVLNFYQKMTMLNTMDRILYESQRQGRISFYMTNYGEEGTHIGSAAALEPTDMVFGQYREAGVLMYRGFPLDLFMAQCYANADDLGKGRQMPVHYGCKDLNFVTISSPLATQIPQAAGAAYALKRENLNRAVICYFGEGAASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMTARGWWSEDDERSWRKQSRKTVMEAFERAERRLKPNPELLFTDVYQEMTPGLSRQRDSMWRHVQQYKEHYPV 444
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Medaka
Match: pdha1a (pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:NCBI gene;Acc:101165911]) HSP 1 Score: 132.109 bits (331), Expect = 1.026e-33 Identity = 87/283 (30.74%), Postives = 130/283 (45.94%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPP 1259
G+E +G +++ +D + YR G RG T++ ++ + G + KG+ +H K N + + +G Q+ AG A A K N VC +GDGAA++G N +S P+IF C NN Y + T R G + +RVDG D+ V AT+ A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK LL+ S E K+ E RK + A + P EL ++ PP
Sbjct: 92 GQEACAVGIEASINMSDHLITAYRAHGYTYTRGGTVKKIMAELTGRRGGIAKGKGGSMHMYCK--NFYGGNGIVGAQVPLGAGVALACKYQGNNELCVCLYGDGAANQGQIFETYNMASLWKLPVIFICENNRYGMGTSVERAAASTDYYKR--GEFIPGLRVDGMDVLCVREATRFAAEHCRSGKGPILMELQTYRYHGHSMSDPGISYRTREEIQEVRSKSDPISLLKDRLLSNNMASVEELKVIDVEVRKEIEDAAQFATTDPEPPLDELCNHMFSNNPP 370
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Medaka
Match: pdha1a (pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:NCBI gene;Acc:101165911]) HSP 1 Score: 131.724 bits (330), Expect = 1.356e-33 Identity = 87/283 (30.74%), Postives = 130/283 (45.94%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPP 1259
G+E +G +++ +D + YR G RG T++ ++ + G + KG+ +H K N + + +G Q+ AG A A K N VC +GDGAA++G N +S P+IF C NN Y + T R G + +RVDG D+ V AT+ A C + P+L+E TYR HS SD ++YR+ +EI +PIS LK LL+ S E K+ E RK + A + P EL ++ PP
Sbjct: 96 GQEACAVGIEASINMSDHLITAYRAHGYTYTRGGTVKKIMAELTGRRGGIAKGKGGSMHMYCK--NFYGGNGIVGAQVPLGAGVALACKYQGNNELCVCLYGDGAANQGQIFETYNMASLWKLPVIFICENNRYGMGTSVERAAASTDYYKR--GEFIPGLRVDGMDVLCVREATRFAAEHCRSGKGPILMELQTYRYHGHSMSDPGISYRTREEIQEVRSKSDPISLLKDRLLSNNMASVEELKVIDVEVRKEIEDAAQFATTDPEPPLDELCNHMFSNNPP 374
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000041277.1 (pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:NCBI gene;Acc:101174054]) HSP 1 Score: 104.76 bits (260), Expect = 3.996e-24 Identity = 86/290 (29.66%), Postives = 126/290 (43.45%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPP 1259
G+E G A++ +D + YR G RG +++ +L + G K KG+ +H + + + +G Q+ AG A A N V +GDGAA++G N ++ P IF C NN Y + T S Y RGD I +RVDG D+ V AT+ A C P+++E TYR HS SD ++YR+ +EI +PIS LK +L S E K RK V +A + P EL + ++ PP
Sbjct: 99 GQEACAAGIEAAINLSDHLITAYRAHGFTYTRGVSVKEILAELTGRKGGVAKGKGGSMHMYAP--HFYGGNGIVGAQVPVGAGIALACSYQGNNQLCVTLYGDGAANQGQIFETFNMAALWKLPCIFICENNKYGMGTAVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATRFAAEHCRAGKGPIVMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISMLKERMLANNMASAEEFKEIDIAIRKEVEEAAQFATLDPEPPLDELCDHIFHNEPP 377
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Medaka
Match: ENSORLT00000029291.1 (pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Source:NCBI gene;Acc:101174054]) HSP 1 Score: 104.375 bits (259), Expect = 5.870e-24 Identity = 86/290 (29.66%), Postives = 126/290 (43.45%), Query Frame = 3
Query: 411 GEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPT-----SEQY--RGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPP 1259
G+E G A++ +D + YR G RG +++ +L + G K KG+ +H + + + +G Q+ AG A A N V +GDGAA++G N ++ P IF C NN Y + T S Y RGD I +RVDG D+ V AT+ A C P+++E TYR HS SD ++YR+ +EI +PIS LK +L S E K RK V +A + P EL + ++ PP
Sbjct: 106 GQEACAAGIEAAINLSDHLITAYRAHGFTYTRGVSVKEILAELTGRKGGVAKGKGGSMHMYAP--HFYGGNGIVGAQVPVGAGIALACSYQGNNQLCVTLYGDGAANQGQIFETFNMAALWKLPCIFICENNKYGMGTAVERAAASTDYYKRGDFIPG---------LRVDGMDVLCVREATRFAAEHCRAGKGPIVMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPISMLKERMLANNMASAEEFKEIDIAIRKEVEEAAQFATLDPEPPLDELCDHIFHNEPP 384
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Planmine SMEST
Match: SMESG000021408.1 (SMESG000021408.1) HSP 1 Score: 899.812 bits (2324), Expect = 0.000e+0 Identity = 426/428 (99.53%), Postives = 426/428 (99.53%), Query Frame = 3
Query: 75 MHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPTAYETPKPITNE 1358
MHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKV LPNPMELFEDVYDKMP RLYKQMSKQYSFMVKNKDLFPTAYETPKPITNE
Sbjct: 1 MHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVPLPNPMELFEDVYDKMPQRLYKQMSKQYSFMVKNKDLFPTAYETPKPITNE 428
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Planmine SMEST
Match: SMESG000021409.1 (SMESG000021409.1) HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0 Identity = 279/402 (69.40%), Postives = 328/402 (81.59%), Query Frame = 3
Query: 144 VSIDTPQFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPTAYETPKPI 1349
S D P FP SRSEYT+ L F++PTDI+GI +YRVL+ G + DP SKE I++ K MTLLN DRI+YDSQRQGRISFYMT++GEEG Q+GSA AL+ DL+FGQYREAGVGLWRG+T+E MLNQCYGNK D KG+QMP+HY NK N FSISS LGTQ+ HA GAAYAFKR QNG C +CYFGDGA+S GDAHAA+NFS+TLDCP+I CRNN YAISTP EQYRGDGI SR GYG+A IRVDGND+ AVYNATKAAR LCVNENRPVLIEAMTYR+GSHSTSDDSLAYRSVDE++WWDKHDNPI R K YL + WWS+ EE+ WR+E+RKLVV+AIEK EK LPNP+ LFEDVYD+MP R+ QM+K Y+F+ +NK+ +P +Y++P+ I
Sbjct: 26 TSADKPNFPQSRSEYTSQLNFIYPTDIKGIPLYRVLDGNGNLREDGLDPKFSKEFSIKIIKTMTLLNTMDRILYDSQRQGRISFYMTHYGEEGVQIGSAAALNDGDLIFGQYREAGVGLWRGFTLEEMLNQCYGNKYDSNKGKQMPIHYANKKLNYFSISSVLGTQMPHAVGAAYAFKRAQNGKCVICYFGDGASSVGDAHAALNFSATLDCPVIMLCRNNLYAISTPVHEQYRGDGIGSRGIGYGIATIRVDGNDLIAVYNATKAARELCVNENRPVLIEAMTYRIGSHSTSDDSLAYRSVDEVTWWDKHDNPILRFKFYLKQKNWWSDKEEEAWRNESRKLVVQAIEKAEKTNLPNPLILFEDVYDEMPTRIRSQMNKHYTFLKRNKEHYPISYDSPEKI 427
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Planmine SMEST
Match: SMESG000021412.1 (SMESG000021412.1) HSP 1 Score: 424.861 bits (1091), Expect = 7.601e-146 Identity = 194/396 (48.99%), Postives = 275/396 (69.44%), Query Frame = 3
Query: 162 QFPGSRSEYTTHLKFLFPTDIEGISVYRVLNREGQIMGQDNDPNISKETLIEMFKKMTLLNIFDRIMYDSQRQGRISFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFKRNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVYDKMPPRLYKQMSKQYSFMVKNKDLFPTAYETPKPI 1349
FP + YT LKF + ++++L+ GQ++ + + I++E L++M + M +LN FD + + Q++ IS Y T+FGEEG Q+GSA AL +ND+VF QYRE GVGLWRG+ +E MLNQ + NK+D +G+QMP+HY+NKD N FSISSPLGTQ+ A G +Y K + +CYFG+G AS GDA A+NF++TL+CP+IFFCRNNGYAISTPT EQY GDG+A+R G+G++ ++VDGND AVY ATK AR + +N+PVLIEAMTYRVG+H+T + +AYR +DE+ +W+ +DNP+ R + +L+++ WS+ + KI+ E R + IE+ + + NP+ LFEDVYD M P L KQM K F+ N++ +P +E P PI
Sbjct: 34 HFPPPETIYTNKLKFYDCLNKWNFPIFQILDTNGQLIDPNQEIGITQEDLVKMMQTMIILNTFDILANELQQKKIISLYATSFGEEGLQIGSAAALAENDMVFTQYREPGVGLWRGFDMEDMLNQLFANKDDINRGKQMPIHYSNKDINFFSISSPLGTQMPQAVGYSYMNKIQKKKQGVICYFGEGTASVGDAFVALNFAATLECPIIFFCRNNGYAISTPTDEQYHGDGLAARGCGFGISTLKVDGNDPLAVYLATKTAREFSIEQNQPVLIEAMTYRVGNHTTDEHGIAYRCMDEVKYWELNDNPLLRFQTFLIDRKLWSKEKNKIFHKECRDKINFLIERAQNKSYGNPLVLFEDVYDSMNPILKKQMEKFSKFLALNREHYPGNFENPNPI 429
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Planmine SMEST
Match: SMESG000073271.1 (SMESG000073271.1) HSP 1 Score: 121.324 bits (303), Expect = 1.579e-30 Identity = 87/311 (27.97%), Postives = 139/311 (44.69%), Query Frame = 3
Query: 318 MFKKMTLLNIFDRIMYDSQRQGRI-SFYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY 1244
M KKM + + + + ++ I F + G+E +G AL D + YR G + RG +I ++ + G K +G+ +H K N + + +G Q+ AG A A K + NG+C Y GDGAA++G A N + + P IF C NN + + T S + + G + I VDG D+ V A + C + P+++E TYR HS SD +YR+ +E+ K +PI+ L + + K E + V A+E + PNP+E + VY
Sbjct: 1 MLKKMFQIRRMETVCGNLYKEKLIRGFCHLSSGQEAVAVGIEAALIPADSIITSYRCHGFTMTRGASIHSIIAELMGKKTGVSEGKGGSMHMYGK--NYYGGNGIVGAQVPLGAGIALAHKYKKDNGVCITLY-GDGAANQGQVFEAYNIAKLWNLPCIFICENNHFGMGT--SAKRSSASVNYYTRGDYIPGIWVDGMDVLTVREALRFCTKWCRDGFGPIIVEMETYRYSGHSMSDPGTSYRTREEVQAVRKEKDPITLFTKALQSANLLDDETSKKIEKEVKDEVNAAMELCKSDPEPNPIEAYTHVY 306
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Planmine SMEST
Match: SMESG000073271.1 (SMESG000073271.1) HSP 1 Score: 119.013 bits (297), Expect = 9.132e-30 Identity = 82/285 (28.77%), Postives = 128/285 (44.91%), Query Frame = 3
Query: 393 FYMTNFGEEGAQLGSAVALDKNDLVFGQYREAGVGLWRGYTIEGMLNQCYGNKNDFGKGRQMPVHYTNKDANIFSISSPLGTQLLHAAGAAYAFK-RNQNGLCTVCYFGDGAASEGDAHAAMNFSSTLDCPMIFFCRNNGYAISTPTSEQYRGDGIASRASGYGMACIRVDGNDIFAVYNATKAARNLCVNENRPVLIEAMTYRVGSHSTSDDSLAYRSVDEISWWDKHDNPISRLKHYLLNQGWWSEGEEKIWRDEARKLVVKAIEKTEKVALPNPMELFEDVY 1244
F + G+E +G AL D + YR G + RG +I ++ + G K +G+ +H K N + + +G Q+ AG A A K + NG+C Y GDGAA++G A N + + P IF C NN + + T S + + G + I VDG D+ V A + C + P+++E TYR HS SD +YR+ +E+ K +PI+ L + + K E + V A+E + PNP+E + VY
Sbjct: 23 FCHLSSGQEAVAVGIEAALIPADSIITSYRCHGFTMTRGASIHSIIAELMGKKTGVSEGKGGSMHMYGK--NYYGGNGIVGAQVPLGAGIALAHKYKKDNGVCITLY-GDGAANQGQVFEAYNIAKLWNLPCIFICENNHFGMGT--SAKRSSASVNYYTRGDYIPGIWVDGMDVLTVREALRFCTKWCRDGFGPIIVEMETYRYSGHSMSDPGTSYRTREEVQAVRKEKDPITLFTKALQSANLLDDETSKKIEKEVKDEVNAAMELCKSDPEPNPIEAYTHVY 302 The following BLAST results are available for this feature:
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of 2-oxoisovalerate dehydrogenase subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012717 ID=SMED30012717|Name=2-oxoisovalerate dehydrogenase subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=1486bpback to top protein sequence of SMED30012717-orf-1 >SMED30012717-orf-1 ID=SMED30012717-orf-1|Name=SMED30012717-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=429bp MHTFKHFLFTSRSKIFQAKFSSNVSIDTPQFPGSRSEYTTHLKFLFPTDIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
