Kinase

Overview
NameKinase
Smed IDSMED30012688
Length (bp)897
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Kinase (SMED30012688) t-SNE clustered cells

Violin plots show distribution of expression levels for Kinase (SMED30012688) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kinase (SMED30012688) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kinase (SMED30012688) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30012688

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30012688h1SMcG0007377 dd_Smed_v4_13774_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30012688h1SMcG0007377 dd_Smed_v4_13774_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30012688h1SMcG0007377 dd_Smed_v4_13774_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Kinase vs. Ensembl Human
Match: STK17A (serine/threonine kinase 17a [Source:HGNC Symbol;Acc:HGNC:11395])

HSP 1 Score: 97.0561 bits (240), Expect = 3.343e-22
Identity = 59/230 (25.65%), Postives = 114/230 (49.57%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDL--KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + ++ HE+ +L+L + +P++IN+     V ET    I +L Y   G++  +   ++        ++ +   + + V FL +  ++H D+K +NIL+ S +   D+K++DF  +       E  E  GT  Y+APE+   +  S   D+WSIGV+ Y + T   PF   +K   ++ N      +Y  +      +   + +  + V + ++R +AE+CL+  WL
Sbjct:   96 RKGQDCRMEIIHEIAVLELAQDNPWVINLHE---VYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFL-NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWL 321
[Close]
BLAST of Kinase vs. Ensembl Human
Match: STK17A (serine/threonine kinase 17a [Source:HGNC Symbol;Acc:HGNC:11395])

HSP 1 Score: 97.0561 bits (240), Expect = 3.343e-22
Identity = 59/230 (25.65%), Postives = 114/230 (49.57%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDL--KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + ++ HE+ +L+L + +P++IN+     V ET    I +L Y   G++  +   ++        ++ +   + + V FL +  ++H D+K +NIL+ S +   D+K++DF  +       E  E  GT  Y+APE+   +  S   D+WSIGV+ Y + T   PF   +K   ++ N      +Y  +      +   + +  + V + ++R +AE+CL+  WL
Sbjct:   96 RKGQDCRMEIIHEIAVLELAQDNPWVINLHE---VYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFL-NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWL 321
[Close]
BLAST of Kinase vs. Ensembl Human
Match: PHKG2 (phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931])

HSP 1 Score: 94.3597 bits (233), Expect = 3.869e-22
Identity = 58/202 (28.71%), Postives = 104/202 (51.49%), Query Frame = 3 
Query:   99 LYQRIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNK 686
            +++   ++ A+ +  +  E +  +   + +E    E  IL+     P+II +I     + +   F++    ++G+L  YL +   L   + +SI  +L +AV FL + +I+HRD+K ENIL++ +     ++L DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R +
Sbjct:   42 VHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDS--YESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN---MQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQ 238
[Close]
BLAST of Kinase vs. Ensembl Human
Match: PHKG2 (phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931])

HSP 1 Score: 94.3597 bits (233), Expect = 5.027e-22
Identity = 58/202 (28.71%), Postives = 104/202 (51.49%), Query Frame = 3 
Query:   99 LYQRIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNK 686
            +++   ++ A+ +  +  E +  +   + +E    E  IL+     P+II +I     + +   F++    ++G+L  YL +   L   + +SI  +L +AV FL + +I+HRD+K ENIL++ +     ++L DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R +
Sbjct:   42 VHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLID--SYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN---MQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQ 238
[Close]
BLAST of Kinase vs. Ensembl Human
Match: STK33 (serine/threonine kinase 33 [Source:HGNC Symbol;Acc:HGNC:14568])

HSP 1 Score: 96.2857 bits (238), Expect = 9.971e-22
Identity = 61/176 (34.66%), Postives = 97/176 (55.11%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSS------AFFFDVKLIDFENAVAYNPLSEP--SERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            KA S A + +E E+ ILK   K  +II++  E   +  K+ ++++  C++G+LK  L++      ++ + I  +L  A+ +L +  I+HRD+K ENI++ SS          ++K+ DF  AV     SE      CGT  Y+APE+   + YS   DIWSIGVV+Y L   + PF
Sbjct:  110 KAGSSAVKLLEREVNILKSV-KHEHIIHL--EQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPF 282
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: par-1 (Serine/threonine-protein kinase par-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW45])

HSP 1 Score: 89.7373 bits (221), Expect = 1.061e-19
Identity = 73/251 (29.08%), Postives = 123/251 (49.00%), Query Frame = 3 
Query:  114 FYKIAIYVNFIKNELVIVKA------NSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRN--KHSEYVRNSK---DFRFNYKHQTLRKHF-----QFRELLENIFVSQYKNRW 812
            F K+ +  + I    V +K       N  + +++  E+KI+K  +      NI+    V ET+Q  +++L Y   G++  YL  H  +   + ++    +  AV++L S +IIHRD+K EN+L++      ++K+ DF  +  ++  ++    CG+  Y APE+F    Y    VD+WS+GV+LY L +   PF  +N  +  E V   K    F  +   + L K F     Q R  L+NI     K+RW
Sbjct:  117 FAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHP----NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQD---MNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIM----KDRW 356
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: par-1 (Serine/threonine-protein kinase par-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW45])

HSP 1 Score: 89.7373 bits (221), Expect = 1.061e-19
Identity = 73/251 (29.08%), Postives = 123/251 (49.00%), Query Frame = 3 
Query:  114 FYKIAIYVNFIKNELVIVKA------NSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRN--KHSEYVRNSK---DFRFNYKHQTLRKHF-----QFRELLENIFVSQYKNRW 812
            F K+ +  + I    V +K       N  + +++  E+KI+K  +      NI+    V ET+Q  +++L Y   G++  YL  H  +   + ++    +  AV++L S +IIHRD+K EN+L++      ++K+ DF  +  ++  ++    CG+  Y APE+F    Y    VD+WS+GV+LY L +   PF  +N  +  E V   K    F  +   + L K F     Q R  L+NI     K+RW
Sbjct:  117 FAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHP----NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQD---MNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIM----KDRW 356
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: par-1 (Serine/threonine-protein kinase par-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW45])

HSP 1 Score: 89.7373 bits (221), Expect = 1.061e-19
Identity = 73/251 (29.08%), Postives = 123/251 (49.00%), Query Frame = 3 
Query:  114 FYKIAIYVNFIKNELVIVKA------NSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRN--KHSEYVRNSK---DFRFNYKHQTLRKHF-----QFRELLENIFVSQYKNRW 812
            F K+ +  + I    V +K       N  + +++  E+KI+K  +      NI+    V ET+Q  +++L Y   G++  YL  H  +   + ++    +  AV++L S +IIHRD+K EN+L++      ++K+ DF  +  ++  ++    CG+  Y APE+F    Y    VD+WS+GV+LY L +   PF  +N  +  E V   K    F  +   + L K F     Q R  L+NI     K+RW
Sbjct:  117 FAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHP----NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQD---MNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIM----KDRW 356
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: par-1 (Serine/threonine-protein kinase par-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW45])

HSP 1 Score: 89.7373 bits (221), Expect = 1.061e-19
Identity = 73/251 (29.08%), Postives = 123/251 (49.00%), Query Frame = 3 
Query:  114 FYKIAIYVNFIKNELVIVKA------NSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRN--KHSEYVRNSK---DFRFNYKHQTLRKHF-----QFRELLENIFVSQYKNRW 812
            F K+ +  + I    V +K       N  + +++  E+KI+K  +      NI+    V ET+Q  +++L Y   G++  YL  H  +   + ++    +  AV++L S +IIHRD+K EN+L++      ++K+ DF  +  ++  ++    CG+  Y APE+F    Y    VD+WS+GV+LY L +   PF  +N  +  E V   K    F  +   + L K F     Q R  L+NI     K+RW
Sbjct:  117 FAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHP----NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQD---MNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIM----KDRW 356
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: par-1 (Serine/threonine-protein kinase par-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TW45])

HSP 1 Score: 89.7373 bits (221), Expect = 1.061e-19
Identity = 73/251 (29.08%), Postives = 123/251 (49.00%), Query Frame = 3 
Query:  114 FYKIAIYVNFIKNELVIVKA------NSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRN--KHSEYVRNSK---DFRFNYKHQTLRKHF-----QFRELLENIFVSQYKNRW 812
            F K+ +  + I    V +K       N  + +++  E+KI+K  +      NI+    V ET+Q  +++L Y   G++  YL  H  +   + ++    +  AV++L S +IIHRD+K EN+L++      ++K+ DF  +  ++  ++    CG+  Y APE+F    Y    VD+WS+GV+LY L +   PF  +N  +  E V   K    F  +   + L K F     Q R  L+NI     K+RW
Sbjct:  117 FAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHP----NIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQD---MNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIM----KDRW 356
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: inaC (gene:FBgn0004784 transcript:FBtr0087047)

HSP 1 Score: 88.9669 bits (219), Expect = 2.210e-19
Identity = 66/235 (28.09%), Postives = 113/235 (48.09%), Query Frame = 3 
Query:  135 VNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSER---CGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR--ELLENIFVSQYKNRWSAEK 824
            V  ++ +++I    +D  E   +E KIL L  + P+++++    C +   + F ++ YCK GDL  ++ ++     S     A  +  A+ FL    II+RD+K +NIL++       VKL+DF   ++   ++E       CGT  Y+APE+   + YS   D WS GV+L+     Q PF + +  +   RN KD     K     KHF     +++ +    +  NR  A +
Sbjct:  399 VKVLRKDVII---QTDDMELPMNEKKILALSGRPPFLVSM--HSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGH---VKLVDF--GLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF-EGDDETTVFRNIKD-----KKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGR 617
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0343587)

HSP 1 Score: 87.4261 bits (215), Expect = 2.847e-19
Identity = 57/187 (30.48%), Postives = 96/187 (51.34%), Query Frame = 3 
Query:  189 EQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENF------YSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNY 731
            E    E+ IL+     PYII++  +   +     F++   C +G+L  YL     L   + ++I   +F+ V+++ + SI+HRD+K ENIL++ +    +VK+ DF  A       + +  CGT GY+APE    N       YS  VDIW+ GV+++ L     PF  R K    +RN  + ++++
Sbjct:   72 EATRQEISILRQVMGHPYIIDL--QDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDEN---HNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHR-KQMVMLRNIMEGKYSF 252
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0090002)

HSP 1 Score: 87.4261 bits (215), Expect = 3.334e-19
Identity = 57/187 (30.48%), Postives = 96/187 (51.34%), Query Frame = 3 
Query:  189 EQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENF------YSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNY 731
            E    E+ IL+     PYII++  +   +     F++   C +G+L  YL     L   + ++I   +F+ V+++ + SI+HRD+K ENIL++ +    +VK+ DF  A       + +  CGT GY+APE    N       YS  VDIW+ GV+++ L     PF  R K    +RN  + ++++
Sbjct:   72 EATRQEISILRQVMGHPYIIDL--QDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDEN---HNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHR-KQMVMLRNIMEGKYSF 252
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: PhKgamma (gene:FBgn0011754 transcript:FBtr0343648)

HSP 1 Score: 87.4261 bits (215), Expect = 3.334e-19
Identity = 57/187 (30.48%), Postives = 96/187 (51.34%), Query Frame = 3 
Query:  189 EQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENF------YSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNY 731
            E    E+ IL+     PYII++  +   +     F++   C +G+L  YL     L   + ++I   +F+ V+++ + SI+HRD+K ENIL++ +    +VK+ DF  A       + +  CGT GY+APE    N       YS  VDIW+ GV+++ L     PF  R K    +RN  + ++++
Sbjct:   72 EATRQEISILRQVMGHPYIIDL--QDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDEN---HNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHR-KQMVMLRNIMEGKYSF 252
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: PKD (gene:FBgn0038603 transcript:FBtr0330313)

HSP 1 Score: 87.4261 bits (215), Expect = 6.417e-19
Identity = 55/194 (28.35%), Postives = 99/194 (51.03%), Query Frame = 3 
Query:  276 ETKQRFIILPYCKEGDLKTYLNKHSELHISQ--IKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRK-HFQFRELLENIFVSQYKNRWSAEKCLQSNWLH 848
            ET +R  ++    +GD+   +  H+   +S+   K +   +  A+K+L S +I+H D+K EN+L++S A F  VKL DF  A      S      GT  Y+APE+     Y+  +D+WS+GV++Y   +  FPF +    ++ ++N+    F Y     ++      +L+ N+   + + R++ +K L   WL 
Sbjct:  610 ETPERIFVVMEKLKGDMLEMILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEEEDINDQIQNAA---FMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQ 800
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: stk17a (serine/threonine kinase 17a [Source:ZFIN;Acc:ZDB-GENE-030131-5556])

HSP 1 Score: 100.138 bits (248), Expect = 1.057e-23
Identity = 57/237 (24.05%), Postives = 119/237 (50.21%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDL--KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRK-HFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLDPLDVL 869
            +   D + ++ HE+ +L+L    P ++N+      +   +  ++L Y   G++  +   ++       ++K +   + + V FL + +++H D+K +NIL+ S +   D+K++DF  +   +   E  E  GT  Y+APE+ +    S   D+WSIGV++Y + T   PF   +K   ++ N      +Y  + L +        ++++ + + +NR +AE CL+  WL  +  D++
Sbjct:   80 RKGQDCRTEIIHEIAVLELAAACPRVVNL--HEVYEMPSEMVLVLEYAAGGEIFNQCVADRDEAFTEQEVKRLMKQILEGVSFLHNNNVVHLDLKPQNILLTSESPLGDIKIVDFGLSRLLSNSHEVREIMGTPEYVAPEVLNYEPISTATDMWSIGVLVYVMLTGISPFLGDDKQETFL-NISQINISYSEEELEQLDGSAIRFIKSLLIKEPENRATAEDCLKHQWLQTEEQDLI 313
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: stk17b (serine/threonine kinase 17b (apoptosis-inducing) [Source:ZFIN;Acc:ZDB-GENE-040426-1499])

HSP 1 Score: 98.5969 bits (244), Expect = 2.909e-23
Identity = 59/230 (25.65%), Postives = 108/230 (46.96%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFII-LPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWLHL 851
            +   D +  V HE+ +L+  + +P ++N+     V ET    ++ L +   G++  +      L   QI  +   + + +  L   S++H D+K +NIL+ S +   D+K++DF  A       E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   ++ N       Y  +T  +  +   + +  + V   ++R SA  C+   WL L
Sbjct:   67 RRGRDCRADVIHEIAVLEAAKNNPRVVNLN---AVYETDYDLVLMLEFAAGGEIFNHCVSDELLPEGQITRLIRQMLEGIHLLHQSSVVHLDLKPQNILLTSLSPLGDIKIVDFGLARRLGSAGELREILGTPEYVAPEILNYEPITTATDLWSVGVITYMLVTGESPFAGDDKQETFL-NVSQVNVEYSRETFSRVSELAVDFIRKLLVKAPEDRPSAADCMTHPWLWL 292
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: stk17b (serine/threonine kinase 17b (apoptosis-inducing) [Source:ZFIN;Acc:ZDB-GENE-040426-1499])

HSP 1 Score: 98.5969 bits (244), Expect = 2.909e-23
Identity = 59/230 (25.65%), Postives = 108/230 (46.96%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFII-LPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWLHL 851
            +   D +  V HE+ +L+  + +P ++N+     V ET    ++ L +   G++  +      L   QI  +   + + +  L   S++H D+K +NIL+ S +   D+K++DF  A       E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   ++ N       Y  +T  +  +   + +  + V   ++R SA  C+   WL L
Sbjct:   67 RRGRDCRADVIHEIAVLEAAKNNPRVVNLN---AVYETDYDLVLMLEFAAGGEIFNHCVSDELLPEGQITRLIRQMLEGIHLLHQSSVVHLDLKPQNILLTSLSPLGDIKIVDFGLARRLGSAGELREILGTPEYVAPEILNYEPITTATDLWSVGVITYMLVTGESPFAGDDKQETFL-NVSQVNVEYSRETFSRVSELAVDFIRKLLVKAPEDRPSAADCMTHPWLWL 292
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: stk17al (serine/threonine kinase 17a like [Source:ZFIN;Acc:ZDB-GENE-061103-427])

HSP 1 Score: 95.9005 bits (237), Expect = 3.122e-22
Identity = 59/235 (25.11%), Postives = 109/235 (46.38%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDL---KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWLHLDPL 860
            +   D +  + +E+ +L+  E +PY++ +     V ET    I++  C  G     +   +         +  +A  +   V  L   +I+H D+K +NIL+ S+    D++++DF  +   + +SE  E  GT  Y+APE+ D    S   D+WSIGV+ Y + T + PF    K   ++ N      +Y     +         ++++ +   + R + E+CL  +WL LD L
Sbjct:   60 RKGQDCRGDILNEIAVLESAEANPYVVGLHE---VYETTSEIILVLECAAGGEIFNQCVADNDEAFTEKDVIRLARQILMGVSCLHQNNIVHLDLKPQNILLTSAQPLGDIRIVDFGLSRRVDSVSEVREILGTPEYVAPEILDYEPISTATDMWSIGVLTYVMLTGESPFLGEEKQETFL-NISQVNVDYSQDVFQGISDLAVNFIQSLLIKNPRKRSTVEQCLNHSWLRLDSL 290
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: phkg2 (phosphorylase kinase, gamma 2 (testis) [Source:ZFIN;Acc:ZDB-GENE-040426-825])

HSP 1 Score: 95.9005 bits (237), Expect = 3.941e-22
Identity = 68/240 (28.33%), Postives = 120/240 (50.00%), Query Frame = 3 
Query:  153 ELVIVKANSDAQEQVEH-------ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCL 830
            +++ + A    ++Q+E        E+ +L L +  P II +I     + T   F++    + G+L  YL +   L   + +S+   L +AV++L +++I+HRD+K ENIL++       +KL DF  +V   P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R K    +R   + R+ +       +    ++L+  + V +   R +AE+ L
Sbjct:   53 KIIEITAEKMTEQQLEEVKSSTLKEIHVLNLVKGHPSIITLIDS--YESTAFIFLVFDLMRRGELFDYLTEKVTLSEKETRSMMRALLEAVQYLHALNIVHRDLKPENILLDDQGH---LKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCSMDETHEGYGKEVDLWACGVILFTLLAGSPPFWHR-KQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLISRLLVVEPTLRLTAEQAL 286
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: xpo5 (exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328])

HSP 1 Score: 92.4337 bits (228), Expect = 7.596e-21
Identity = 66/217 (30.41%), Postives = 108/217 (49.77%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCLQ 833
            E++IL      P II++I     + +   F++    K G+L  YL +   L   + + I  +L +AV +L S +I+HRD+K ENIL++      ++KL DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+++ L     PF  R K    +R   D RF +       +    ++L+  +     + R +AE+ LQ
Sbjct:   42 EMEILHHVSNHPSIISLIDS--YESSTFIFLVFDLMKRGELFDYLTEKVTLSEKETRCIMRSLLEAVTYLHSNNIVHRDLKPENILMDDC---LNIKLSDFGFSCILKPTEKLRELCGTPGYLAPEILKCSMDETHPGYGREVDLWACGVIMFTLLAGSPPFWHR-KQMLMLRMIMDGRFQFGSPEWDDRSSTVKDLICRLLEVCPEKRLTAEQALQ 252
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: xpo5 (exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328])

HSP 1 Score: 92.4337 bits (228), Expect = 8.357e-21
Identity = 66/217 (30.41%), Postives = 108/217 (49.77%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCLQ 833
            E++IL      P II++I     + +   F++    K G+L  YL +   L   + + I  +L +AV +L S +I+HRD+K ENIL++      ++KL DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+++ L     PF  R K    +R   D RF +       +    ++L+  +     + R +AE+ LQ
Sbjct:   37 EMEILHHVSNHPSIISLIDS--YESSTFIFLVFDLMKRGELFDYLTEKVTLSEKETRCIMRSLLEAVTYLHSNNIVHRDLKPENILMDDC---LNIKLSDFGFSCILKPTEKLRELCGTPGYLAPEILKCSMDETHPGYGREVDLWACGVIMFTLLAGSPPFWHR-KQMLMLRMIMDGRFQFGSPEWDDRSSTVKDLICRLLEVCPEKRLTAEQALQ 247
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: xpo5 (exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328])

HSP 1 Score: 92.0485 bits (227), Expect = 1.295e-20
Identity = 66/217 (30.41%), Postives = 108/217 (49.77%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCLQ 833
            E++IL      P II++I     + +   F++    K G+L  YL +   L   + + I  +L +AV +L S +I+HRD+K ENIL++      ++KL DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+++ L     PF  R K    +R   D RF +       +    ++L+  +     + R +AE+ LQ
Sbjct:   74 EMEILHHVSNHPSIISLIDS--YESSTFIFLVFDLMKRGELFDYLTEKVTLSEKETRCIMRSLLEAVTYLHSNNIVHRDLKPENILMDDC---LNIKLSDFGFSCILKPTEKLRELCGTPGYLAPEILKCSMDETHPGYGREVDLWACGVIMFTLLAGSPPFWHR-KQMLMLRMIMDGRFQFGSPEWDDRSSTVKDLICRLLEVCPEKRLTAEQALQ 284
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: xpo5 (exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328])

HSP 1 Score: 92.0485 bits (227), Expect = 1.435e-20
Identity = 66/217 (30.41%), Postives = 108/217 (49.77%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCLQ 833
            E++IL      P II++I     + +   F++    K G+L  YL +   L   + + I  +L +AV +L S +I+HRD+K ENIL++      ++KL DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+++ L     PF  R K    +R   D RF +       +    ++L+  +     + R +AE+ LQ
Sbjct:   77 EMEILHHVSNHPSIISLIDS--YESSTFIFLVFDLMKRGELFDYLTEKVTLSEKETRCIMRSLLEAVTYLHSNNIVHRDLKPENILMDDC---LNIKLSDFGFSCILKPTEKLRELCGTPGYLAPEILKCSMDETHPGYGREVDLWACGVIMFTLLAGSPPFWHR-KQMLMLRMIMDGRFQFGSPEWDDRSSTVKDLICRLLEVCPEKRLTAEQALQ 287
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: xpo5 (exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328])

HSP 1 Score: 92.0485 bits (227), Expect = 1.711e-20
Identity = 66/217 (30.41%), Postives = 108/217 (49.77%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCLQ 833
            E++IL      P II++I     + +   F++    K G+L  YL +   L   + + I  +L +AV +L S +I+HRD+K ENIL++      ++KL DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+++ L     PF  R K    +R   D RF +       +    ++L+  +     + R +AE+ LQ
Sbjct:   77 EMEILHHVSNHPSIISLIDS--YESSTFIFLVFDLMKRGELFDYLTEKVTLSEKETRCIMRSLLEAVTYLHSNNIVHRDLKPENILMDDC---LNIKLSDFGFSCILKPTEKLRELCGTPGYLAPEILKCSMDETHPGYGREVDLWACGVIMFTLLAGSPPFWHR-KQMLMLRMIMDGRFQFGSPEWDDRSSTVKDLICRLLEVCPEKRLTAEQALQ 287
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Stk17b (serine/threonine kinase 17b (apoptosis-inducing) [Source:MGI Symbol;Acc:MGI:2138162])

HSP 1 Score: 93.2041 bits (230), Expect = 4.125e-21
Identity = 58/231 (25.11%), Postives = 115/231 (49.78%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDL-KTYLNKHSELHISQ--IKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQF-RELLENIFVSQYKNRWSAEKCLQSNWLH 848
            +   D + ++ HE+ +L+L    P++IN+      +   +  ++L Y   G++    L + +E+ +S+  +  +   + + V +L   +I+H D+K +NIL++S     D+K++DF  +      SE  E  GT  Y+APE+ + +  +   D+W+IG++ Y L T   PF   +    Y+ N      +Y  +      Q   + ++++ V   + R +AE CL  +WL 
Sbjct:   68 RRGQDCRAEILHEIAVLELARSCPHVINL--HEVYENATEIILVLEYAAGGEIFNLCLPELAEM-VSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYL-NISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQ 294
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Phkg2 (phosphorylase kinase, gamma 2 (testis) [Source:MGI Symbol;Acc:MGI:1916211])

HSP 1 Score: 91.6633 bits (226), Expect = 1.905e-20
Identity = 56/193 (29.02%), Postives = 100/193 (51.81%), Query Frame = 3 
Query:  126 AIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNK 686
            A+ +  +  E + ++   + ++    E+ IL+     P+II +I     + +   F++    ++G+L  YL +   L   + +SI  +L +AV FL + +I+HRD+K ENIL++ +     ++L DF  +       +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R +
Sbjct:   51 AVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLID--SYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN---MQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQ 238
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Phkg2 (phosphorylase kinase, gamma 2 (testis) [Source:MGI Symbol;Acc:MGI:1916211])

HSP 1 Score: 91.6633 bits (226), Expect = 1.905e-20
Identity = 56/193 (29.02%), Postives = 100/193 (51.81%), Query Frame = 3 
Query:  126 AIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNK 686
            A+ +  +  E + ++   + ++    E+ IL+     P+II +I     + +   F++    ++G+L  YL +   L   + +SI  +L +AV FL + +I+HRD+K ENIL++ +     ++L DF  +       +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R +
Sbjct:   51 AVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLID--SYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN---MQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQ 238
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Stk33 (serine/threonine kinase 33 [Source:MGI Symbol;Acc:MGI:2152419])

HSP 1 Score: 88.9669 bits (219), Expect = 9.851e-20
Identity = 55/177 (31.07%), Postives = 98/177 (55.37%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSS------AFFFDVKLIDFENAV-AYNPLSEP--SERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            KA S A + +E E+ ILK      +II++  E   +  ++ ++++  C++G+LK  +++      ++ + I  +L  A+ +L +  I+HRD+K ENI++ SS          ++K+ DF  +V  +   SE      CGT  Y+APE+ + + YS   DIWSIGV+++ L   + PF
Sbjct:   23 KAGSSAMKLLEREVSILKTVNHQ-HIIHL--EQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINAHDYSQQCDIWSIGVIMFILLCGEPPF 196
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Stk33 (serine/threonine kinase 33 [Source:MGI Symbol;Acc:MGI:2152419])

HSP 1 Score: 88.5817 bits (218), Expect = 2.743e-19
Identity = 55/177 (31.07%), Postives = 98/177 (55.37%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSS------AFFFDVKLIDFENAV-AYNPLSEP--SERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            KA S A + +E E+ ILK      +II++  E   +  ++ ++++  C++G+LK  +++      ++ + I  +L  A+ +L +  I+HRD+K ENI++ SS          ++K+ DF  +V  +   SE      CGT  Y+APE+ + + YS   DIWSIGV+++ L   + PF
Sbjct:  146 KAGSSAMKLLEREVSILKTVNHQ-HIIHL--EQVFESPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIYMAPEVINAHDYSQQCDIWSIGVIMFILLCGEPPF 319
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q9GM70|ST17A_RABIT (Serine/threonine-protein kinase 17A OS=Oryctolagus cuniculus OX=9986 GN=STK17A PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 2.669e-22
Identity = 60/230 (26.09%), Postives = 116/230 (50.43%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDL--KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + ++ HE+ +L+L + +P++IN+     V ET    I +L Y   G++  +   ++    +   ++ +   + + V FL +  ++H D+K +NIL+ S +   D+K++DF  +       E  E  GT  Y+APE+   +  S   D+WSIGV+ Y + T   PF   NK   ++ N      +Y  +      +   + ++ + V + ++R +AE+CL+  WL
Sbjct:   79 RKGQDCRMEIIHEIAVLELAQDNPWVINLHE---VYETSSEMILVLEYAAGGEISDQCVADRDEAFNEKDVQRLMRQILEGVHFLHTHDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRIVKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGDNKQETFL-NISQMNLSYSEEEFDTVSESAVDFIKKLLVKKPEDRATAEECLKHPWL 304
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q9UEE5|ST17A_HUMAN (Serine/threonine-protein kinase 17A OS=Homo sapiens OX=9606 GN=STK17A PE=1 SV=2)

HSP 1 Score: 97.0561 bits (240), Expect = 1.606e-21
Identity = 59/230 (25.65%), Postives = 114/230 (49.57%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDL--KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + ++ HE+ +L+L + +P++IN+     V ET    I +L Y   G++  +   ++        ++ +   + + V FL +  ++H D+K +NIL+ S +   D+K++DF  +       E  E  GT  Y+APE+   +  S   D+WSIGV+ Y + T   PF   +K   ++ N      +Y  +      +   + +  + V + ++R +AE+CL+  WL
Sbjct:   96 RKGQDCRMEIIHEIAVLELAQDNPWVINLHE---VYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFL-NISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWL 321
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|F4IRW0|ATG1C_ARATH (Serine/threonine-protein kinase ATG1c OS=Arabidopsis thaliana OX=3702 GN=ATG1C PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 9.005e-21
Identity = 54/173 (31.21%), Postives = 91/173 (52.60%), Query Frame = 3 
Query:  153 ELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            E+ + + N   QE +  E+ IL+     P II +I    +K   +  ++L YCK GDL  Y+ +H  +  +  K     L   ++ L+  +IIHRD+K +N+L++++    D+K+ DF  A +  P       CG+  Y+APE+     Y    D+WS+G +L+ L T + PF
Sbjct:   42 EIAMDRLNKKLQESLMSEIFILRRINH-PNIIRLID--MIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADLKIADFGFARSLQPRGLAETLCGSPLYMAPEIMQLQKYDAKADLWSVGAILFQLVTGRTPF 211
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q9BYT3|STK33_HUMAN (Serine/threonine-protein kinase 33 OS=Homo sapiens OX=9606 GN=STK33 PE=1 SV=1)

HSP 1 Score: 95.1301 bits (235), Expect = 1.128e-20
Identity = 61/176 (34.66%), Postives = 97/176 (55.11%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSS------AFFFDVKLIDFENAVAYNPLSEP--SERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            KA S A + +E E+ ILK   K  +II++  E   +  K+ ++++  C++G+LK  L++      ++ + I  +L  A+ +L +  I+HRD+K ENI++ SS          ++K+ DF  AV     SE      CGT  Y+APE+   + YS   DIWSIGVV+Y L   + PF
Sbjct:  151 KAGSSAVKLLEREVNILKSV-KHEHIIHL--EQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPF 323
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|P15735|PHKG2_HUMAN (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 1.131e-20
Identity = 58/202 (28.71%), Postives = 104/202 (51.49%), Query Frame = 3 
Query:   99 LYQRIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNK 686
            +++   ++ A+ +  +  E +  +   + +E    E  IL+     P+II +I     + +   F++    ++G+L  YL +   L   + +SI  +L +AV FL + +I+HRD+K ENIL++ +     ++L DF  +    P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R +
Sbjct:   42 VHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLID--SYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN---MQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQ 238
[Close]
BLAST of Kinase vs. TrEMBL
Match: M4BFH8 (Protein kinase domain-containing protein OS=Hyaloperonospora arabidopsidis (strain Emoy2) OX=559515 PE=3 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 4.947e-24
Identity = 73/233 (31.33%), Postives = 113/233 (48.50%), Query Frame = 3 
Query:  159 VIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRE----LLENIFVSQYKNRWSAEKCLQSNWL 845
             + K +S A +Q++ E+++L+   K P II I  E       +  ++  Y   G+L  Y+     L   +  +I   +  AV +L +  IIHRD+K ENI++ S +   DVK+IDF  A   +   E +   GT GY+APEM     YS  VD+W++G+++Y L     PF D    S  + N K  R  +  +  R      E    LL  +      NR+SAE+ L   W+
Sbjct:   34 AVEKEHSGAMQQLQVEIQVLQSL-KHPNIIRI--EDVYLSGSKICMVTEYMGGGELFDYVVDRGTLSEVEASTIVRQITSAVDYLHTRGIIHRDLKPENIMLTSKSRGADVKIIDFGLAKLLDADGETASFLGTRGYLAPEMLQRQAYSMSVDMWALGIIVYILLCGCLPFDD---ESSKIANDKAARARFGLRFPRWANGLSESAKDLLRQLLEVDSANRYSAEQTLAHPWV 260
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A4W5LLC5 (Protein kinase domain-containing protein OS=Hucho hucho OX=62062 PE=3 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 3.049e-23
Identity = 59/227 (25.99%), Postives = 108/227 (47.58%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + +V HE+ +L+    +P ++N+  +   +      ++L Y   G++  Y +    L   QI  +   + + V  L   S++H D+K +NIL+ S A   D+K++DF  A     + E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   Y+ N      +Y  +   +  +   + +  + V   ++R SA  C+   WL
Sbjct:   67 RQGRDCRAEVVHEMAVLEAARNNPRVVNL--QAAYETDHDIILLLEYAAGGEIFDYCDCDELLPEGQITRLIRQMLEGVHLLHQTSVVHLDLKPQNILLTSLAPLGDIKIVDFGLARKLGTVGELREILGTPEYVAPEILNYEPITTATDLWSVGVITYMLVTGESPFAGDDKQETYL-NVSQVNVDYSQEAFSRVSELAVDFIRKLLVKTPEDRPSAADCMTHPWL 290
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A060XX95 (Protein kinase domain-containing protein OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00031984001 PE=3 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 3.379e-23
Identity = 59/227 (25.99%), Postives = 108/227 (47.58%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + +V HE+ +L+    +P ++N+  +   +      ++L Y   G++  Y +    L   QI  +   + + V  L   S++H D+K +NIL+ S A   D+K++DF  A     + E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   Y+ N      +Y  +   +  +   + +  + V   ++R SA  C+   WL
Sbjct:   67 RQGRDCRAEVVHEMAVLEAARNNPRVVNL--QAAYETDHDIILLLEYAAGGEIFDYCDCDELLPEGQITRLIRQMLEGVHLLHQTSVVHLDLKPQNILLTSLAPLGDIKIVDFGLARKLGTVGELREILGTPEYVAPEILNYEPITTATDLWSVGVIAYMLVTGESPFAGDDKQETYL-NVSQVNVDYSQEAFSRVSELAVDFIRKLLVKTPEDRSSAADCMTHPWL 290
[Close]
BLAST of Kinase vs. TrEMBL
Match: C0H9H7 (Serine/threonine-protein kinase 17B OS=Salmo salar OX=8030 GN=ST17B PE=2 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 7.478e-23
Identity = 59/227 (25.99%), Postives = 108/227 (47.58%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + +V HE+ +L+    +P ++N+  +   +      ++L Y   G++  Y +    L   QI  +   + + V  L   S++H D+K +NIL+ S A   D+K++DF  A     + E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   Y+ N      +Y  +   +  +   + +  + V   ++R SA  C+   WL
Sbjct:   67 RQGRDCRAEVVHEMAVLEAACNNPRVVNL--QAAYETDHDIILLLEYAAGGEIFDYCDCDELLPEGQITRLIRQMLEGVHLLHQTSVVHLDLKPQNILLTSLAPLGDIKIVDFGLARKLGTVGELREILGTPEYVAPEILNYEPITTATDLWSVGVIAYMLVTGESPFAGDDKQETYL-NVSQVNVDYSQEAFSRVSELAVDFIRKLLVKTPEDRSSAADCMTHPWL 290
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A182FKF6 (Protein kinase domain-containing protein OS=Anopheles albimanus OX=7167 PE=4 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 8.581e-23
Identity = 68/228 (29.82%), Postives = 120/228 (52.63%), Query Frame = 3 
Query:  195 VEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSER-------CGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLD 854
            +  EL +L L  + PYI+ I  +  +K   +  I + Y + GDL ++L +H  L   Q++     L  A+++L +  I+HRD+KCEN+L++++   F+VKL DF    A     +P++R       CG+F Y APE+     Y+    D+W++GV+LY LF +  PF  + +     + ++ ++F   H +     + + L+ N+       RW+ E+ L  +WL  D
Sbjct:   67 LPRELTVL-LHVRHPYIVRI--QAIIKCRSKVCIFMRYAEMGDLLSFLVQHGPLREPQMRIWCRQLALAIQYLHTSGIVHRDLKCENVLLSAN---FNVKLTDF--GFARYVTEQPNQRVQMSSTFCGSFDYSAPELLKGQPYNPKASDVWALGVLLYILFNKSVPFKGKTRQVYQQQMARAWKFR-SHVSSTLSPEVKSLIRNLLEPNPLVRWTIEEVLVCDWLVQD 285
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: phkg2 (phosphorylase kinase catalytic subunit gamma 2 [Source:NCBI gene;Acc:103041098])

HSP 1 Score: 93.9745 bits (232), Expect = 2.002e-21
Identity = 67/244 (27.46%), Postives = 119/244 (48.77%), Query Frame = 3 
Query:  120 KIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCL 830
            ++A+ V  I  E + V+   + +     E+ +L + +  P II ++     +     F++    + G+L  YL +   L   + + +   L +AV++L S++I+HRD+K ENIL++       +KL DF  +V   P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R K    +R   + R+ +       +    ++L+  + V     R +AE+ L
Sbjct:   48 ELAVKVIEITAEKMTVQQLEEVKSSTLKEIHVLNVLKGHPSIITLVDS--YESATFIFLVFDLMRRGELFDYLTEKVTLSEKETRYMMRALLEAVQYLHSLNIVHRDLKPENILLDDQGH---IKLSDFGFSVQLRPGQKLRELCGTPGYLAPEILKCSMDETHEGYGKEVDLWACGVILFTLLAGSPPFWHR-KQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLISRLLVVDPPLRLTAEQAL 285
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: phkg2 (phosphorylase kinase catalytic subunit gamma 2 [Source:NCBI gene;Acc:103041098])

HSP 1 Score: 93.9745 bits (232), Expect = 2.002e-21
Identity = 67/244 (27.46%), Postives = 119/244 (48.77%), Query Frame = 3 
Query:  120 KIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCL 830
            ++A+ V  I  E + V+   + +     E+ +L + +  P II ++     +     F++    + G+L  YL +   L   + + +   L +AV++L S++I+HRD+K ENIL++       +KL DF  +V   P  +  E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R K    +R   + R+ +       +    ++L+  + V     R +AE+ L
Sbjct:   48 ELAVKVIEITAEKMTVQQLEEVKSSTLKEIHVLNVLKGHPSIITLVDS--YESATFIFLVFDLMRRGELFDYLTEKVTLSEKETRYMMRALLEAVQYLHSLNIVHRDLKPENILLDDQGH---IKLSDFGFSVQLRPGQKLRELCGTPGYLAPEILKCSMDETHEGYGKEVDLWACGVILFTLLAGSPPFWHR-KQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLISRLLVVDPPLRLTAEQAL 285
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: stk17b (serine/threonine kinase 17b [Source:NCBI gene;Acc:103028616])

HSP 1 Score: 93.2041 bits (230), Expect = 2.314e-21
Identity = 57/228 (25.00%), Postives = 105/228 (46.05%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIIL-PYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +   D + +V HE+ +L+  + +P ++N+       ET+   ++L  Y   G++  +      L   Q+  +     + +  L   +++H D+K +NIL+ S     D+KL+DF  A       E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   ++ N      +Y  +   +  +     +  + V   ++R SA  CL   WL
Sbjct:   67 RRGRDCKAEVIHEMAVLEAAKSNPRVVNLH---AAYETEHDIVLLLEYAAGGEIFEHCVSDELLSEGQVIRLIRQTLEGIHQLHQSNVVHLDLKPQNILLTSLNPLGDIKLVDFGLARRLGSAGELREILGTPEYVAPEILNYEPITTASDLWSVGVITYMLITGESPFAGEDKQQTFL-NVSQVNVDYSKEAFARVSELAVHFIRKLLVKAPEDRPSAADCLSHPWL 290
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: rskra (putative serine/threonine-protein kinase F31E3.2 [Source:NCBI gene;Acc:103030447])

HSP 1 Score: 92.8189 bits (229), Expect = 6.217e-21
Identity = 53/166 (31.93%), Postives = 79/166 (47.59%), Query Frame = 3 
Query:  231 KSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSER----CGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKD 716
            + P+++++  E C +  +  FI+  YC  GDL TY     +    +I+  A  L  A+ FL    IIHRD+K ENIL+        ++L DF      +   E  ER    CGT  Y+APE+     Y    D WS+G+++Y L   +FP      HS  +    D
Sbjct:  144 RHPFLLSL--EDCWQSQRHLFIMCEYCSTGDLYTYWTLTGQFDEKEIRVFAAELGSALGFLHDFGIIHRDVKMENILLTEQGH---LRLADF----GLSRRLECGERAFTICGTIQYMAPEVLSGGPYGHAADWWSLGILIYALAAGEFPVPPEADHSNMLTTVTD 300
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: rskrb (ribosomal protein S6 kinase related [Source:NCBI gene;Acc:103046934])

HSP 1 Score: 91.2781 bits (225), Expect = 2.403e-20
Identity = 55/193 (28.50%), Postives = 93/193 (48.19%), Query Frame = 3 
Query:  147 KNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRF 725
            K+E++ +     ++E+V     I++   + P++ ++  + C +  +  +I+  YC  GDL TY     +   + +K  A  L  A+ FL    IIHRD+K ENIL+        ++L DF  +            CGT  Y+APE+     YS   D WS+G++L+ L T +FP      H   +R  + F +
Sbjct:  126 KSEILRLGVLDQSKEEV-----IVQRQVRHPFVHDL--QDCWQTQRHLYIMCDYCSTGDLYTYWVMIGQFGENAVKVFAAELGSALGFLHDFGIIHRDVKMENILLTDQG---HLRLADFGLSRRLERGGRAFTICGTIQYMAPEVLSGGPYSHAADWWSLGILLFALATGKFPVPPEPDHCSMLRKVRSFPY 308
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: phkg1b (phosphorylase kinase, gamma 1b (muscle) [Source:ZFIN;Acc:ZDB-GENE-050522-52])

HSP 1 Score: 99.7525 bits (247), Expect = 3.159e-24
Identity = 64/216 (29.63%), Postives = 113/216 (52.31%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLR-KHFQFRELLENIFVSQYKNRWSAEKCL 830
            E+ ILK     P+II +I     + +   F++    K G+L  YL +   L     +SI  ++F+ V FL + +I+HRD+K ENIL++ +    +++L DF  ++   P     E CGT GY++PE+     DE+   +G  VD+W+ GV++Y L     PF  R K    +R   D ++++       +    ++L+  + V + + R++AE+ L
Sbjct:   78 EVDILKAVSGHPHIITLID--AYESSTFFFLVFDLMKRGELFDYLTEKVALSEKDTRSIMRSIFEVVHFLHAKNIVHRDLKPENILLDDN---MNIRLSDFGFSMQLRPGERLRELCGTPGYLSPELLKCSMDESHPGYGKEVDLWACGVIMYTLLAGSPPFWHR-KQMTMLRLIMDGKYDFSTPEWEDRSDTVKDLISRLLVVEPEKRFTAEQAL 287
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: stk17b (serine/threonine kinase 17b (apoptosis-inducing) [Source:ZFIN;Acc:ZDB-GENE-040426-1499])

HSP 1 Score: 98.9821 bits (245), Expect = 4.456e-24
Identity = 65/250 (26.00%), Postives = 115/250 (46.00%), Query Frame = 3 
Query:  108 RIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDLKTYLNKHSELHISQI--KSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRK-HFQFRELLENIFVSQYKNRWSAEKCLQSNWL 845
            R   ++A  + F    L   +   D +  V HE+ IL+     P+II++       ET    I +L Y   G++        E   +++  + +   + + V FL    ++H D+K +NIL+ S++   D+K++DF  +   N   E  E  GT  Y+APE+ +    S   D+WS+GV+ Y + T + PF   +K   ++ N      +Y+ +       Q    ++ + V     R +AE CL+  WL
Sbjct:   10 RRCVEVATGIEFAAKFLRKRRKGQDCRADVTHEMAILEAARSCPHIIDLHDAF---ETPTEIILVLEYAVGGEIFNQCVAEGEDAFTEVDVRRLMRQILEGVAFLHRNDVVHLDLKPQNILLTSASPLGDIKIVDFGLSRRVNSAEELREIMGTPEYVAPEVLNYEPISKATDMWSVGVLAYVMLTGESPFLGEDKQETFL-NVSQLNVSYEPEVFEGVSVQAVAFIQQLLVKAPHRRATAEHCLRHPWL 255
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: stk33 (serine/threonine kinase 33 [Source:ZFIN;Acc:ZDB-GENE-040724-242])

HSP 1 Score: 90.1225 bits (222), Expect = 2.811e-21
Identity = 73/258 (28.29%), Postives = 119/258 (46.12%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAF-----FFDVKLIDF------ENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEY---VRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLD------PLDVLNKL 878
            +A S     +E E+ ILK  +      NII    V ET +R ++++  C+ G+L+  L +   L  ++ + +A +L  A+ +L    I+HRD+K ENIL  SS         D+++ DF      E   A + L  P   CGT  Y+A E+     YS   D+WSIGV+LY L   + PF   ++   +   ++    F      +        +ELL  +      +R +A + L  +W+  D      PL+VL  +
Sbjct:   40 RAGSSGVRLLEREVVILKRVQHQ----NIIHLEEVLETHKRVYLVMELCELGELRAVLEQRKRLSEAEARHVAHSLAGAIAYLHKHDIVHRDLKLENILAKSSEPHEGIDHLDIRVTDFGLSAVREGNGAASMLQSP---CGTPIYMAAEVIQSQDYSQQCDVWSIGVILYMLLCGEPPFMAHSQEKLFELIIKGELSFTQPAWEEVSES---AKELLRGLLKVDPAHRLTASELLHDHWVTGDTSSLGRPLNVLEMM 287
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: rps6ka5 (ribosomal protein S6 kinase, polypeptide 5 [Source:ZFIN;Acc:ZDB-GENE-130530-693])

HSP 1 Score: 91.6633 bits (226), Expect = 3.272e-21
Identity = 53/170 (31.18%), Postives = 80/170 (47.06%), Query Frame = 3 
Query:  186 QEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDF--------ENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            +   + E+  LKLC   P I+NII      +T   ++++   K G+L   + K S    ++   I   L  A  F+    ++HRD+K EN+L         +K+IDF        +NA    PL  P   C T  Y APE+     Y    D+WS+GV+LY + + Q PF
Sbjct:  147 EANTQREIAALKLCHAHPNIVNIID--VYHDTLHTYLVMELLKGGELLERIKKRSHFSETEASRIMRKLVSATSFMHDTGVVHRDLKPENLLFADDTEGAAIKVIDFGFARLKPQDNA----PLKTP---CFTLQYAAPELLQHAGYDESCDVWSLGVILYTMLSGQVPF 307
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897])

HSP 1 Score: 83.5741 bits (205), Expect = 2.154e-18
Identity = 68/270 (25.19%), Postives = 132/270 (48.89%), Query Frame = 3 
Query:   81 QIDNYYLYQRI----FYKIAIYVNFIKNELVIVK------ANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFG-VDIWSIGVVLYYLFTRQFPFGDRN--KHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHL 851
            ++ NY L + I    F K+ +  + +  + V VK       N+ + +++  E++I+K+    P I+ +   I +++T   ++++ Y   G++  YL  H  +   + ++    +  AV++     I+HRD+K EN+L+++     ++K+ DF  +  +   S+    CG+  Y APE+F    Y    VD+WS+GV+LY L +   PF  +N  +  E V   K +R  +   T         LL+   V     R S E+ ++  W+++
Sbjct:   64 RVGNYRLLKTIGKGNFAKVKLAKHTLTGQEVAVKIIDKTQLNTSSLQKLFREVRIMKVLNH-PNIVKLFEVIEMEKT--LYLVMEYSSGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDAD---MNIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK-YRIPFYMST-----DCENLLKRFLVLHPLKRGSLEQIMKDRWMNV 321
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: RAD53 (DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074])

HSP 1 Score: 92.4337 bits (228), Expect = 2.121e-21
Identity = 61/237 (25.74%), Postives = 109/237 (45.99%), Query Frame = 3 
Query:  189 EQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF-------------DENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLDPL 860
            + V  EL++L+     P I+ + G    ++T+  ++++ +   GDL  ++  H  +     + I+  +  A+K++ S+ I HRD+K +NILI        VK+ DF  A      S     CGT  Y+APE+              + N YS  VD+WS+G ++Y + T   PF    +   Y +  +        +  R   + R+ ++++      NR +A K L   W+ + PL
Sbjct:  239 DGVTRELEVLQKLNH-PRIVRLKG--FYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQDDPVL-VKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKMSPL 471
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 87.0409 bits (214), Expect = 1.219e-19
Identity = 59/170 (34.71%), Postives = 90/170 (52.94%), Query Frame = 3 
Query:  237 PYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSER----CGTFGYIAPE--MFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVR-NSKDFRF 725
            P I+  I   C ++    +I+L  C  G L   L +   L   +++     +  A+K++ S  +IHRD+K  NI  +S+   +++K+ DF  A     L+  SER    CGT  YIAPE  M   + +SF VDIWS+GV+LY L   + PF  R+ ++ Y R   +DF F
Sbjct:  139 PNIVQFID--CFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSN---YNLKIGDFGLAAV---LANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSF 300
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: KIN1 (Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication [Source:SGD;Acc:S000002529])

HSP 1 Score: 85.8853 bits (211), Expect = 3.228e-19
Identity = 57/204 (27.94%), Postives = 101/204 (49.51%), Query Frame = 3 
Query:  237 PYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWL 845
            P+I  +  E+C   +   +++  Y   G L  Y+ +H  +   Q +  A  +  A+ +L + +I+HRD+K ENI+I+ S+   ++K+IDF  +  Y+   +    CG+  + APE+   N Y+   VD+WS GVVL+ L   + PF D N  S      K  +  Y         +   LL  + V   K R + ++ ++ +W+
Sbjct:  204 PHICRLF-EMCTL-SNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSS---EIKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENS-SVLHEKIKQGKVEYPQHL---SIEVISLLSKMLVVDPKRRATLKQVVEHHWM 398
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: KIN2 (Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086])

HSP 1 Score: 83.1889 bits (204), Expect = 2.936e-18
Identity = 48/150 (32.00%), Postives = 81/150 (54.00%), Query Frame = 3 
Query:  237 PYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRN 683
            P+I  +  E+C   +   +++  Y   G L  Y+ +H  L     +  A  +  A+++L + +I+HRD+K ENI+I+SS    ++K+IDF  +  ++   +    CG+  + APE+     Y+   VDIWS G+VLY L   + PF D N
Sbjct:  183 PHICRLF-EMCTM-SNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSG---EIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDEN 327
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 81.2629 bits (199), Expect = 6.534e-18
Identity = 57/183 (31.15%), Postives = 94/183 (51.37%), Query Frame = 3 
Query:  159 VIVKANSDAQEQVEH---ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEY 698
            V+ K      +QVEH   E ++LKL E  P++I + G    ++ +  F+++ Y + G+L + L K         K  A  +  A+++L + +II+RD+K ENIL++ +     +K+ DF  A     ++     CGT  YIAPE+     Y+  VD WS+GV++Y +     PF D      Y
Sbjct:  100 VLKKQQVVKMKQVEHTNDERRMLKLVEH-PFLIRMWG--TFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGH---IKITDFGFAKEVQTVT--WTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTY 274
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO47961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKT6])

HSP 1 Score: 96.6709 bits (239), Expect = 1.169e-23
Identity = 55/185 (29.73%), Postives = 93/185 (50.27%), Query Frame = 3 
Query:  291 FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSF-GVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNW 842
            ++IL   + GDL  Y+NK++ L   + + I       + +     ++HRD+KCEN+L++++     +K+ DF  A   +  +     CG++ Y +PE+   + Y     DIWS+GVVLY L   + PFGD +  +   R  +  RF+ K        + REL+  +     K R +AE+ L   W
Sbjct:   82 YLILELAEGGDLLEYINKNALLPEERARVIFCQFVATMAYCHKERVVHRDLKCENLLLDANG---RLKITDFGFACNTHKTNILQTFCGSYAYCSPEILRGDLYDGQASDIWSMGVVLYALVCARLPFGDDDLRAIMNREPRKLRFSKKTSK-----ECRELIRKMLALDEKKRPTAEELLHEPW 258
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO40703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6E0])

HSP 1 Score: 90.8929 bits (224), Expect = 2.567e-21
Identity = 55/173 (31.79%), Postives = 93/173 (53.76%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILIN--SSAFFFDVKLIDFENAVAYNPLSEPS---ERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPF 671
            KA S A + +E E+ I+K      ++I++  E   + +K+ ++++  C  G L   L +       +  ++   L  AV +L  + I+HRD+K ENIL++  +     +VK+ DF  ++    +   S     CGT  Y+APE+ D+  YS   D+WSIGV++Y LFT + PF
Sbjct:   62 KAGSSAVKLLEREVMIMKKIYHE-HLIHL--EEIYETSKRMYLVMELCDAGGLDKMLERKKRFTEKETWTVIKQLVSAVAYLHDLDIVHRDLKLENILLSHPTGNELLNVKITDFGLSIVKGGVGSDSMMQSVCGTPMYMAPEVIDDLGYSQQCDVWSIGVIMYTLFTGRPPF 231
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO46091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR18])

HSP 1 Score: 88.1965 bits (217), Expect = 1.686e-20
Identity = 63/228 (27.63%), Postives = 115/228 (50.44%), Query Frame = 3 
Query:  180 DAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRF-IILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILIN--SSAFFFDVKLIDFENAVAYNPLSEPSER--CGTFGYIAPEMFDENFY-SFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWL 845
            +A  QV+H+           Y+I++I    V E+ +RF ++L   + GDL   L K  +LH ++ + I   +   V       I HRD+K ENIL++  +     D     +    +   ++ P     CG++ Y APE+     Y +   D+WS+GVVL+ + T +FPF D+++  + +R++   +F+Y   + R   Q +EL++N+  +  K+R + E+     W+
Sbjct:   58 EALRQVDHK-----------YVISLIE---VLESSKRFYLVLELAQNGDLLQLLQKKKQLHENEARKIFKKIVKGVLHCHRKGIAHRDLKLENILLSRKNEPIISDFGFARYVGGSSDTCMTRPRSNTFCGSYAYAAPEILQGIPYDATSSDVWSLGVVLFAMVTGRFPFDDQDRR-QLLRHTLAGKFSYPKGSARLSDQLKELVKNMLTADIKSRLTLEEVYDHPWI 270
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO44594 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV77])

HSP 1 Score: 88.5817 bits (218), Expect = 5.394e-20
Identity = 67/234 (28.63%), Postives = 109/234 (46.58%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF------DENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRK-HFQFRELLENIFVSQYKNRWSAEKCLQSNWLH 848
            +  SD       E+ IL   +    II +  E   + T   F++     +G+L  YL +   L   Q + I  ++F+AV ++   +++HRD+K ENIL++      +VK+ DF  AV         E CGT GY+APE+       D   Y+  VD+W+ GV+LY L     PF  R +    +RN  + ++N+            + L++ + V   K R +A   L+  WL 
Sbjct:   60 QGGSDIIATTRDEVNILLSLQGHKNIIRL--EDVFESTAFFFLVFEIAPKGELFDYLTEKVTLSEKQTRRIMLSIFEAVDYMHYHNVVHRDLKPENILLDEE---INVKISDFGFAVELKEGETLRELCGTPGYLAPEVLQCSMFPDAPGYTKEVDMWACGVILYTLLCGFPPFWHR-RQVVMLRNIMNGKYNFSSPEWEDVSNDAKNLIKKLLVVHPKERITASDALKHPWLQ 287
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO33625 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRN4])

HSP 1 Score: 86.6557 bits (213), Expect = 1.787e-19
Identity = 56/197 (28.43%), Postives = 95/197 (48.22%), Query Frame = 3 
Query:  276 ETKQR-FIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSER------CGTFGYIAPEMFDENFYSFGV-DIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNW 842
            ET  R +IIL     GDL  Y+  +  +  ++ +     L DAV++L +  ++HRD+KCENIL+N         + DF  A   + +++  +R      CG++ Y  PE+     Y   + DIWS+GVVLY + +   PF D N      + S+D  F+ + +      + ++L+  + V+  K R       +  W
Sbjct:  129 ETSSRIYIILDLADNGDLLEYIRSNGAIPENEARLFYHQLVDAVEYLHNKGVVHRDLKCENILLNRDNRIL---ISDFGFARTQHVMADTGKRRLSQTFCGSYAYAPPEILRGIAYDGTLADIWSLGVVLYTMVSASLPFDDTNLKVLLEQVSRDVVFSRRKKI---SDEVKDLVRRMLVADVKTRIDLASIRRHPW 319
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: phkg2 (phosphorylase kinase catalytic subunit gamma 2 [Source:NCBI gene;Acc:101165598])

HSP 1 Score: 97.4413 bits (241), Expect = 8.880e-23
Identity = 69/244 (28.28%), Postives = 119/244 (48.77%), Query Frame = 3 
Query:  120 KIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCL 830
            ++A+ +  I  E +  +   + +     E+ +L + +  P II +I     + T   F++    + G+L  YL +   L   + +SI   L +AV++L S++I+HRD+K ENIL++       +KL DF  +V   P     E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R K    +R   + R+ +       +    ++L+  + V     R +AE+ L
Sbjct:   32 ELAVKIIEITAEKMTAQQLEEVKSSTLKEIHLLNMVKGHPSIITLIDS--YESTTFIFLVFDLMRRGELFDYLTEKVTLSEKETRSIMRALLEAVQYLHSLNIVHRDLKPENILLDDHGH---IKLSDFGFSVQLEPGKNLRELCGTPGYLAPEILKCSMDEMHPGYGKEVDLWACGVILFTLLAGSPPFWHR-KQMLMLRLIMEGRYQFSSPEWDDRSDTVKDLISRLLVVDSAARLTAEQAL 269
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: phkg2 (phosphorylase kinase catalytic subunit gamma 2 [Source:NCBI gene;Acc:101165598])

HSP 1 Score: 97.4413 bits (241), Expect = 9.765e-23
Identity = 69/244 (28.28%), Postives = 119/244 (48.77%), Query Frame = 3 
Query:  120 KIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMF----DENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTL-RKHFQFRELLENIFVSQYKNRWSAEKCL 830
            ++A+ +  I  E +  +   + +     E+ +L + +  P II +I     + T   F++    + G+L  YL +   L   + +SI   L +AV++L S++I+HRD+K ENIL++       +KL DF  +V   P     E CGT GY+APE+     DE    +G  VD+W+ GV+L+ L     PF  R K    +R   + R+ +       +    ++L+  + V     R +AE+ L
Sbjct:   49 ELAVKIIEITAEKMTAQQLEEVKSSTLKEIHLLNMVKGHPSIITLID--SYESTTFIFLVFDLMRRGELFDYLTEKVTLSEKETRSIMRALLEAVQYLHSLNIVHRDLKPENILLDDHGH---IKLSDFGFSVQLEPGKNLRELCGTPGYLAPEILKCSMDEMHPGYGKEVDLWACGVILFTLLAGSPPFWHR-KQMLMLRLIMEGRYQFSSPEWDDRSDTVKDLISRLLVVDSAARLTAEQAL 286
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: stk17b (serine/threonine kinase 17b [Source:NCBI gene;Acc:101163368])

HSP 1 Score: 93.5893 bits (231), Expect = 1.712e-21
Identity = 58/220 (26.36%), Postives = 103/220 (46.82%), Query Frame = 3 
Query:  192 QVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +V HE+ +L+L   +  ++N+       ET    + IL Y   G++         L   QI  +     + V  L   +++H D+K +NIL+ S     D+K++DF  A     + E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   Y+ N      +Y  +   K  +   + ++ + V   ++R +A +C+   WL
Sbjct:   76 EVIHEMAVLELARNNARVVNLH---SAHETDHDIVLILEYAAGGEIFDLCVSEEMLPEPQITRLIRQTLEGVHNLHQSNLVHLDLKPQNILLTSQLPPGDIKIVDFGLARRLGAVGELREILGTPEYVAPEVLNYEPITTATDMWSVGVIAYMLVTGESPFAGDDKQETYL-NVSQVNVDYSKEAFSKVSELAVDFIQKLLVKAPEDRPTAAECMTHPWL 291
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: stk17b (serine/threonine kinase 17b [Source:NCBI gene;Acc:101163368])

HSP 1 Score: 93.2041 bits (230), Expect = 2.765e-21
Identity = 58/220 (26.36%), Postives = 103/220 (46.82%), Query Frame = 3 
Query:  192 QVEHELKILKLCEKSPYIINIIGEICVKETKQRFI-ILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNWL 845
            +V HE+ +L+L   +  ++N+       ET    + IL Y   G++         L   QI  +     + V  L   +++H D+K +NIL+ S     D+K++DF  A     + E  E  GT  Y+APE+ +    +   D+WS+GV+ Y L T + PF   +K   Y+ N      +Y  +   K  +   + ++ + V   ++R +A +C+   WL
Sbjct:   76 EVIHEMAVLELARNNARVVNLHS---AHETDHDIVLILEYAAGGEIFDLCVSEEMLPEPQITRLIRQTLEGVHNLHQSNLVHLDLKPQNILLTSQLPPGDIKIVDFGLARRLGAVGELREILGTPEYVAPEVLNYEPITTATDMWSVGVIAYMLVTGESPFAGDDKQETYL-NVSQVNVDYSKEAFSKVSELAVDFIQKLLVKAPEDRPTAAECMTHPWL 291
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: stk17al (serine/threonine-protein kinase 17A [Source:NCBI gene;Acc:101163818])

HSP 1 Score: 89.3521 bits (220), Expect = 6.409e-20
Identity = 58/246 (23.58%), Postives = 112/246 (45.53%), Query Frame = 3 
Query:  168 KANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDL---KTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFR-ELLENIFVSQYKNRWSAEKCLQSNW------LHLDPLDVLNK 875
            +   D +  + +E+ +L+  + +PY++ +     V ET    I++  C  G     +   +         +  +A  +   V FL   +++H D+K +NIL+  +    D++++DF  +   + + E  E  GT  Y+APE+      S   D+WSIGV+ Y + T + PF    K   ++ N      +Y   T         + ++++ V   + R +AE+CL+  W      LH+ P   L++
Sbjct:   59 RKGEDCRMDIMNEIAVLESAKANPYVVALHE---VYETTSEIILVLECAAGGEIFNQCVADNDEAFTEKDVIRLAKQILTGVAFLHRNNVVHLDLKPQNILLTCAKPLGDIRIVDFGLSRRMDNVREVREILGTPEYVAPEVLSYEPISTATDMWSIGVLTYVMLTGESPFLGDEKQQTFL-NISQVNVDYSQDTFEGISSLAVDFIKSLLVKNPRKRATAEECLRHPWLNSHQHLHMRPASSLDE 300
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000068045.1 (SMESG000068045.1)

HSP 1 Score: 582.022 bits (1499), Expect = 0.000e+0
Identity = 283/283 (100.00%), Postives = 283/283 (100.00%), Query Frame = 3 
Query:   33 MRILTTLNEESNKDFPQIDNYYLYQRIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLDPLDVLNKLM 881
            MRILTTLNEESNKDFPQIDNYYLYQRIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLDPLDVLNKLM
Sbjct:    1 MRILTTLNEESNKDFPQIDNYYLYQRIFYKIAIYVNFIKNELVIVKANSDAQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWLHLDPLDVLNKLM 283
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000016872.1 (SMESG000016872.1)

HSP 1 Score: 101.679 bits (252), Expect = 5.392e-25
Identity = 73/237 (30.80%), Postives = 106/237 (44.73%), Query Frame = 3 
Query:  189 EQVEHELKILKLCEKSPYIINI----IGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHF------------------QFRELLENIFVSQYKNRWSAEKCLQ 833
            EQ   EL IL   + S Y + I    IGE+         ++L Y +   L  Y +K   L I ++  +   LF A+KFLK   IIHRDIK ENIL    +  FDVK+ DF  +           +CGT  Y+APE+     ++  +DIWS+GV LY L T   PF   +  +  + N        KH+ + K +                  ++    E  FV +  +R S E C++
Sbjct:   54 EQYRDELLILNTLKNSEYFVRIETGFIGEM------GPTLVLEYMEGYTLNYYTDKKHLLTIKKMVEVTIKLFKALKFLKKSEIIHRDIKPENILTTCKSLDFDVKIGDFGLSAQLPTCKFMKGQCGTVHYMAPEVIMMRTHTIAIDIWSMGVTLYRLVTSTLPFHHYDSEALNINNVVQLVCPTKHEIIVKIYRIFLWNPIQAYKSVNIVGKYFRFFERAFVVEPSHRISVESCVK 284
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000056960.1 (SMESG000056960.1)

HSP 1 Score: 98.5969 bits (244), Expect = 7.327e-24
Identity = 64/224 (28.57%), Postives = 108/224 (48.21%), Query Frame = 3 
Query:  204 ELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLN----KHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILI------NSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIGVVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLENIFVSQYKNRWSAEKCLQSNWL 845
            E+KIL+  +    ++ ++    +    + F+ +P+   GDL+ +      K  +   SQI+ I   L   + FLKS +IIHRD+K ENI++      + +  F ++KLIDFE AV Y+P   P +  GT  Y APE+       F VDIWS+  VL+ + T          +  + +N+       +H  ++++ +   LL  +       R S E C+   W+
Sbjct:   60 EIKILENIQHCKTVVELVDSF-ITPNDEVFLQMPFYATGDLEKFTAALKMKKRKFTDSQIRQIMMQLLQTLLFLKSQNIIHRDVKLENIIVKDVYYKSKTKLFINIKLIDFECAVIYDPQFPPQDNVGTNQYKAPEVLTNKPQDFKVDIWSLATVLFSMKT----------NVCFDKNTA-----LRHPVIKRNKKLLNLLSGMLEENPLKRLSVEACISHPWM 267
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000038340.1 (SMESG000038340.1)

HSP 1 Score: 95.1301 bits (235), Expect = 3.766e-22
Identity = 59/174 (33.91%), Postives = 95/174 (54.60%), Query Frame = 3 
Query:  186 QEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEM----FDENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKH 689
            + +   E++IL+L    PYII +      +     F+I   C +G+L  +LN    L   + + I   +F+AV F+ S +I+HRD+K ENIL++ +    ++K+ DF  AV  + L E  E  GT GY+APE     +++N   +G  VD+W+ GV++Y L     PF  R +H
Sbjct:   65 RAECHREVEILRLVAGQPYIIEL--HDFYESEVYMFLIFELCPKGELFDHLNARVTLSEKRTRLIMSQIFEAVTFIHSKNIVHRDLKPENILLDDN---LNIKITDFGLAVKTDNLEELKEIRGTPGYLAPEALAVGYNDNQPPYGQPVDVWACGVIMYTLLVGCPPFWHRKQH 233
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000038340.1 (SMESG000038340.1)

HSP 1 Score: 95.1301 bits (235), Expect = 4.761e-22
Identity = 59/174 (33.91%), Postives = 95/174 (54.60%), Query Frame = 3 
Query:  186 QEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKTYLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFFFDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEM----FDENFYSFG--VDIWSIGVVLYYLFTRQFPFGDRNKH 689
            + +   E++IL+L    PYII +      +     F+I   C +G+L  +LN    L   + + I   +F+AV F+ S +I+HRD+K ENIL++ +    ++K+ DF  AV  + L E  E  GT GY+APE     +++N   +G  VD+W+ GV++Y L     PF  R +H
Sbjct:   65 RAECHREVEILRLVAGQPYIIEL--HDFYESEVYMFLIFELCPKGELFDHLNARVTLSEKRTRLIMSQIFEAVTFIHSKNIVHRDLKPENILLDDN---LNIKITDFGLAVKTDNLEELKEIRGTPGYLAPEALAVGYNDNQPPYGQPVDVWACGVIMYTLLVGCPPFWHRKQH 233
The following BLAST results are available for this feature:
BLAST of Kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
STK17A3.343e-2225.65serine/threonine kinase 17a [Source:HGNC Symbol;Ac... [more]
STK17A3.343e-2225.65serine/threonine kinase 17a [Source:HGNC Symbol;Ac... [more]
PHKG23.869e-2228.71phosphorylase kinase catalytic subunit gamma 2 [So... [more]
PHKG25.027e-2228.71phosphorylase kinase catalytic subunit gamma 2 [So... [more]
STK339.971e-2234.66serine/threonine kinase 33 [Source:HGNC Symbol;Acc... [more]
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BLAST of Kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
par-11.061e-1929.08Serine/threonine-protein kinase par-1 [Source:Uni... [more]
par-11.061e-1929.08Serine/threonine-protein kinase par-1 [Source:Uni... [more]
par-11.061e-1929.08Serine/threonine-protein kinase par-1 [Source:Uni... [more]
par-11.061e-1929.08Serine/threonine-protein kinase par-1 [Source:Uni... [more]
par-11.061e-1929.08Serine/threonine-protein kinase par-1 [Source:Uni... [more]
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BLAST of Kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inaC2.210e-1928.09gene:FBgn0004784 transcript:FBtr0087047[more]
PhKgamma2.847e-1930.48gene:FBgn0011754 transcript:FBtr0343587[more]
PhKgamma3.334e-1930.48gene:FBgn0011754 transcript:FBtr0090002[more]
PhKgamma3.334e-1930.48gene:FBgn0011754 transcript:FBtr0343648[more]
PKD6.417e-1928.35gene:FBgn0038603 transcript:FBtr0330313[more]
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BLAST of Kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk17a1.057e-2324.05serine/threonine kinase 17a [Source:ZFIN;Acc:ZDB-G... [more]
stk17b2.909e-2325.65serine/threonine kinase 17b (apoptosis-inducing) [... [more]
stk17b2.909e-2325.65serine/threonine kinase 17b (apoptosis-inducing) [... [more]
stk17al3.122e-2225.11serine/threonine kinase 17a like [Source:ZFIN;Acc:... [more]
phkg23.941e-2228.33phosphorylase kinase, gamma 2 (testis) [Source:ZFI... [more]
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BLAST of Kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
xpo57.596e-2130.41exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328][more]
xpo58.357e-2130.41exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328][more]
xpo51.295e-2030.41exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328][more]
xpo51.435e-2030.41exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328][more]
xpo51.711e-2030.41exportin 5 [Source:Xenbase;Acc:XB-GENE-5947328][more]
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BLAST of Kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Stk17b4.125e-2125.11serine/threonine kinase 17b (apoptosis-inducing) [... [more]
Phkg21.905e-2029.02phosphorylase kinase, gamma 2 (testis) [Source:MGI... [more]
Phkg21.905e-2029.02phosphorylase kinase, gamma 2 (testis) [Source:MGI... [more]
Stk339.851e-2031.07serine/threonine kinase 33 [Source:MGI Symbol;Acc:... [more]
Stk332.743e-1931.07serine/threonine kinase 33 [Source:MGI Symbol;Acc:... [more]
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BLAST of Kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9GM70|ST17A_RABIT2.669e-2226.09Serine/threonine-protein kinase 17A OS=Oryctolagus... [more]
sp|Q9UEE5|ST17A_HUMAN1.606e-2125.65Serine/threonine-protein kinase 17A OS=Homo sapien... [more]
sp|F4IRW0|ATG1C_ARATH9.005e-2131.21Serine/threonine-protein kinase ATG1c OS=Arabidops... [more]
sp|Q9BYT3|STK33_HUMAN1.128e-2034.66Serine/threonine-protein kinase 33 OS=Homo sapiens... [more]
sp|P15735|PHKG2_HUMAN1.131e-2028.71Phosphorylase b kinase gamma catalytic chain, live... [more]
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BLAST of Kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
M4BFH84.947e-2431.33Protein kinase domain-containing protein OS=Hyalop... [more]
A0A4W5LLC53.049e-2325.99Protein kinase domain-containing protein OS=Hucho ... [more]
A0A060XX953.379e-2325.99Protein kinase domain-containing protein OS=Oncorh... [more]
C0H9H77.478e-2325.99Serine/threonine-protein kinase 17B OS=Salmo salar... [more]
A0A182FKF68.581e-2329.82Protein kinase domain-containing protein OS=Anophe... [more]
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BLAST of Kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
phkg22.002e-2127.46phosphorylase kinase catalytic subunit gamma 2 [So... [more]
phkg22.002e-2127.46phosphorylase kinase catalytic subunit gamma 2 [So... [more]
stk17b2.314e-2125.00serine/threonine kinase 17b [Source:NCBI gene;Acc:... [more]
rskra6.217e-2131.93putative serine/threonine-protein kinase F31E3.2 [... [more]
rskrb2.403e-2028.50ribosomal protein S6 kinase related [Source:NCBI g... [more]
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BLAST of Kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
phkg1b3.159e-2429.63phosphorylase kinase, gamma 1b (muscle) [Source:ZF... [more]
stk17b4.456e-2426.00serine/threonine kinase 17b (apoptosis-inducing) [... [more]
stk332.811e-2128.29serine/threonine kinase 33 [Source:ZFIN;Acc:ZDB-GE... [more]
rps6ka53.272e-2131.18ribosomal protein S6 kinase, polypeptide 5 [Source... [more]
MARK32.154e-1825.19microtubule affinity regulating kinase 3 [Source:H... [more]
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BLAST of Kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
RAD532.121e-2125.74DNA damage response protein kinase; required for c... [more]
CDC51.219e-1934.71Polo-like kinase; controls targeting and activatio... [more]
KIN13.228e-1927.94Serine/threonine protein kinase involved in regula... [more]
KIN22.936e-1832.00Serine/threonine protein kinase involved in regula... [more]
TPK26.534e-1831.15cAMP-dependent protein kinase catalytic subunit; p... [more]
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BLAST of Kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO479611.169e-2329.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO407032.567e-2131.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO460911.686e-2027.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO445945.394e-2028.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO336251.787e-1928.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
phkg28.880e-2328.28phosphorylase kinase catalytic subunit gamma 2 [So... [more]
phkg29.765e-2328.28phosphorylase kinase catalytic subunit gamma 2 [So... [more]
stk17b1.712e-2126.36serine/threonine kinase 17b [Source:NCBI gene;Acc:... [more]
stk17b2.765e-2126.36serine/threonine kinase 17b [Source:NCBI gene;Acc:... [more]
stk17al6.409e-2023.58serine/threonine-protein kinase 17A [Source:NCBI g... [more]
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BLAST of Kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000068045.10.000e+0100.00SMESG000068045.1[more]
SMESG000016872.15.392e-2530.80SMESG000016872.1[more]
SMESG000056960.17.327e-2428.57SMESG000056960.1[more]
SMESG000038340.13.766e-2233.91SMESG000038340.1[more]
SMESG000038340.14.761e-2233.91SMESG000038340.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30012688 ID=SMED30012688|Name=Kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=897bp
ACTGTTGGATTGTTTAAATTATATTCGACTTCATGAGAATTCTGACAACC
CTTAACGAAGAATCAAACAAAGATTTCCCACAAATAGACAATTACTATTT
GTATCAGAGGATTTTCTATAAAATCGCCATCTATGTGAATTTTATTAAAA
ATGAACTTGTAATCGTCAAAGCCAACTCTGATGCCCAAGAACAAGTCGAA
CACGAATTGAAAATTTTGAAACTTTGTGAAAAAAGTCCCTACATTATTAA
CATTATCGGAGAGATTTGTGTTAAAGAAACCAAGCAGCGATTCATAATTC
TGCCGTATTGCAAAGAGGGAGATTTGAAAACCTATTTAAACAAGCACAGT
GAATTACACATTTCCCAAATCAAATCGATTGCCGGCAATCTGTTTGATGC
GGTGAAATTTTTGAAATCGGTCTCGATTATCCACCGAGACATCAAATGTG
AAAACATCCTCATTAATTCTTCGGCGTTCTTTTTCGATGTGAAGCTGATA
GACTTTGAGAACGCTGTTGCATACAATCCGTTGTCGGAACCGAGTGAAAG
ATGTGGCACTTTTGGATATATTGCACCTGAAATGTTCGATGAAAACTTCT
ATTCGTTTGGAGTTGATATTTGGTCAATTGGTGTTGTGCTGTACTATCTG
TTCACTAGACAGTTTCCTTTTGGAGACAGAAACAAACACAGTGAATACGT
AAGGAACTCGAAAGATTTCAGATTCAACTACAAACATCAAACGTTGAGAA
AACATTTTCAGTTTCGAGAGTTGTTGGAAAATATTTTCGTATCTCAATAT
AAAAATCGCTGGTCAGCAGAGAAATGTCTCCAGTCAAATTGGCTACATTT
GGATCCATTGGATGTTCTCAACAAATTGATGTAAATATTCCTGTATA
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protein sequence of SMED30012688-orf-1

>SMED30012688-orf-1 ID=SMED30012688-orf-1|Name=SMED30012688-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=284bp
MRILTTLNEESNKDFPQIDNYYLYQRIFYKIAIYVNFIKNELVIVKANSD
AQEQVEHELKILKLCEKSPYIINIIGEICVKETKQRFIILPYCKEGDLKT
YLNKHSELHISQIKSIAGNLFDAVKFLKSVSIIHRDIKCENILINSSAFF
FDVKLIDFENAVAYNPLSEPSERCGTFGYIAPEMFDENFYSFGVDIWSIG
VVLYYLFTRQFPFGDRNKHSEYVRNSKDFRFNYKHQTLRKHFQFRELLEN
IFVSQYKNRWSAEKCLQSNWLHLDPLDVLNKLM*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0018105peptidyl-serine phosphorylation
GO:0018107peptidyl-threonine phosphorylation
GO:0035556intracellular signal transduction
GO:0046777protein autophosphorylation
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
GO:0005737cytoplasm
GO:0048471perinuclear region of cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 29..271
e-value: 2.6E-40
score: 149.9
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 46..271
e-value: 1.4E-45
score: 155.7
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 1..271
score: 31.792
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 11..267
e-value: 5.4E-22
score: 75.7
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 28..281
e-value: 5.1E-51
score: 175.8
NoneNo IPR availablePANTHERPTHR24347:SF412CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE Icoord: 38..272
NoneNo IPR availablePANTHERPTHR24347SERINE/THREONINE-PROTEIN KINASEcoord: 38..272
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 132..144
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 28..272