Phospholipid-transporting ATPase

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF-----PKIIA--NSDKDFEIIN-QTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMS-------QIRE--DIEKSLFDSKRENNEKTCKHKEFV----LVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            +ESPDE ALV       F L  RT +++ +    +   + + +L TL FDS+RK MSV+V+   TGEI +  KGADSV+      P  +   N +K    I  +T+  +  YA +GLRTL + K++++E ++++W     + E +L N +  + E    +E+ L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK+ETA++IA+S RL +Q +TV  I+ E++    ++++       Q RE    ++ LF  +  +   +   +  V    LVIDG +L+ I    +L+++FL +  +C  V+CCR TP+QK  +V LV+    V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAIT+FK+LK+L+LVHGH  Y +LARM +   YKN+    ++F+YQ   GFS+S  ID    + F+L  T LPP++FGV DKD S E LLA P++Y +G NS+ Y    FW +++D+ +QSL+ F +P L Y  ++I +  FG    +  +  +  H  +E + W++FH  + +G+  + ++L   + N+ CV+   CN+  NPY V+   +S    YL+  L+  ++L PR
Sbjct:  691 AESPDEAALVHAAHAYSFTLVSRTPEQVTV-RLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQG-KLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSF-LMYFLVSLLYNATCVI---CNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPR 1285          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLE-EVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC----DSENEE 1469
             N+I+T+KY   +F+  N+FEQ  R++NL+F+   +LNFIP V AF    ++IPI  IL VT IKD  EDLRRY SD+ +NNR  L Y +    +    WKD+ VGD I++   E +PAD+L+ +SSDP+G+C +ET  +DGET LKQR V+K         E E+F N     E  N  + KF G  +     ++     C +L+LR   +RNT    GIVIYAG++TK  +NN   R+KRS +E ++N+D+  C+GILI++C++  +G S +   F +        +N + +    L GF  F T II+ Q +IPI+LY+++ELVK  Q+  ++NDL LYDE  D  I  +A NI EDLGQI+ +F DKTGTLT+N+M+FR  +I G  Y  +EN  RL      DS+ EE
Sbjct:   40 GNQIKTSKYTVLSFVPKNIFEQLHRFANLYFVGIAVLNFIPVVNAFQPEVSMIPICVILAVTAIKDAWEDLRRYKSDKVINNRECLIYSRKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV-CEKPNNHLNKFKG--YMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSA-LGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEE 448          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF-----PKIIA--NSDKDFEIIN-QTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMS-------QIRE--DIEKSLFDSKRENNEKTCKHKEFV----LVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKL 3653
            +ESPDE ALV       F L  RT +++ +    +   + + +L TL FDS+RK MSV+V+   TGEI +  KGADSV+      P  +   N +K    I  +T+  +  YA +GLRTL + K++++E ++++W     + E +L N +  + E    +E+ L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK+ETA++IA+S RL +Q +TV  I+ E++    ++++       Q RE    ++ LF  +  +   +   +  V    LVIDG +L+ I    +L+++FL +  +C  V+CCR TP+QK  +V LV+    V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAIT+FK+LK+L+LVHGH  Y +LARM +   YKN+    ++F+YQ   GFS+S  ID    + F+L  T LPP++FGV DKD S E LLA P++Y +G NS+ Y    FW +++D+ +QSL+ F +P L Y  ++I +  FG    +  +  +  H  +E + W++FH  + +G+  + ++L   + N+ CV+   CN+  NPY V+   +S    YL+  L+  ++L PR            S+  +A ++I+KL
Sbjct:  719 AESPDEAALVHAAHAYSFTLVSRTPEQVTV-RLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQG-KLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSF-LMYFLVSLLYNATCVI---CNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA-QKIDKL 1337          

Query:  195 IYPSN--FYIPLTDESKK-VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLE-EVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC----DSENEE 1469
            ++P+N  F+    + S++   NR  TTKY  + F+  NLFEQF R++NL+F+F VILN++P +  F++   ++P+  +L V +IKDG+ED +R+  D+ +N   +  Y++    +    WKD+ VGD I++   E +PAD+L+ +SSDP+G+C +ET  +DGET LKQR V+K         E E+F N     E  N  + KF G  +     ++     C +L+LR   +RNT    GIVIYAG++TK  +NN   R+KRS +E ++N+D+  C+GILI++C++  +G S +   F +        +N + +    L GF  F T II+ Q +IPI+LY+++ELVK  Q+  ++NDL LYDE  D  I  +A NI EDLGQI+ +F DKTGTLT+N+M+FR  +I G  Y  +EN  RL      DS+ EE
Sbjct:   48 VFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV-CEKPNNHLNKFKG--YMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSA-LGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEE 476          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF------PKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQ---------IREDIEKS------LFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
            +ESPDE ALV         L +R  D++ +      + + +E+L TL FDS+RK MSV+++   T EI++  KGADSV+         + A      +I ++T+  +  YA+ GLRTL + KR+L++ EY  W ++  + E +L N+E  + +    +E+NL L+GA G+ED+LQ+ VPE +   ++AG+ IW+LTGDK+ETA++IAY+ +L   +E V  ++  S+     ++ Q         ++   EK+       F S    +  T   +   LVIDG SL+  L  + L+++FL +A  C  V+CCR TP+QK  VV LV+   +  TLAIGDGANDV+MIQ AD+G+G+SG+EG QA +ASDFA+ KF+YL+RL+++HGH  Y +LA M L  FYKN +   ++F++Q   GFS S  IDQ   + F+L+ + LPP++ GV D+D    +LL NPQ+Y +G N + YRPR FW  + D+ +QSLV F++P L Y+++ + +  +G   V+  ++    H+ IE++ W+  +W  C G   + F+    I N+ C         NPY  +   +     YL   ++   +L PRL  +  
Sbjct:  695 AESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKN-LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITC-GFSVLLFFTVALIYNASCATCYP--PSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSL 1295          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLC----CDSENEEL 1472
             +NR++TTKY   +F+  NLFEQF R +N++F+F  +LNF+P V AF  G A+ P+LFIL +T  +D  ED  R+ SD  +N+   L + +   ++    WK+I VGD ++L   E  PAD+L+  SSDP G+C IET ++DGET LK+R V++      +    +      E E  N  + +F G I  H  GK    L   NL+LR   LRNT+ V GIVIYAG++TK  +NN   R+KRS LE Q+N D+L C+ +L+ + + + +G   ++  + + +++ ++  +              F T IIV Q +IPI+LY+++E+VKA Q+  I  D+ LYDE  D ++  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  ++ G  Y  + N  RL      DSE EE+
Sbjct:   60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGCII-HDNGKKA-GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEV 471          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF------PKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQ---------IREDIEKS------LFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
            +ESPDE ALV         L +R  D++ +      + + +E+L TL FDS+RK MSV+++   T EI++  KGADSV+         + A      +I ++T+  +  YA+ GLRTL + KR+L++ EY  W ++  + E +L N+E  + +    +E+NL L+GA G+ED+LQ+ VPE +   ++AG+ IW+LTGDK+ETA++IAY+ +L   +E V  ++  S+     ++ Q         ++   EK+       F S    +  T   +   LVIDG SL+  L  + L+++FL +A  C  V+CCR TP+QK  VV LV+   +  TLAIGDGANDV+MIQ AD+G+G+SG+EG QA +ASDFA+ KF+YL+RL+++HGH  Y +LA M L  FYKN +   ++F++Q   GFS S  IDQ   + F+L+ + LPP++ GV D+D    +LL NPQ+Y +G N + YRPR FW  + D+ +QSLV F++P L Y+++ + +  +G   V+  ++    H+ IE++ W+  +W  C G   + F+    I N+ C         NPY  +   +     YL   ++   +L PRL  +  
Sbjct:  695 AESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKN-LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITC-GFSVLLFFTVALIYNASCATCYP--PSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSL 1295          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLC----CDSENEEL 1472
             +NR++TTKY   +F+  NLFEQF R +N++F+F  +LNF+P V AF  G A+ P+LFIL +T  +D  ED  R+ SD  +N+   L + +   ++    WK+I VGD ++L   E  PAD+L+  SSDP G+C IET ++DGET LK+R V++      +    +      E E  N  + +F G I  H  GK    L   NL+LR   LRNT+ V GIVIYAG++TK  +NN   R+KRS LE Q+N D+L C+ +L+ + + + +G   ++  + + +++ ++  +              F T IIV Q +IPI+LY+++E+VKA Q+  I  D+ LYDE  D ++  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  ++ G  Y  + N  RL      DSE EE+
Sbjct:   60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGCII-HDNGKKA-GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEV 471          

Query: 1461 NEELHNNP----HILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFD-YGVXXXXXXXXXXXXXDTDPIPKDLI----------------KAVFEKAESLQSVSSYPKSNITADNFPHRHLTN---EELS--PLIL-----SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI-IANSD------KDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEK---------SLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIK 3590
            +E + N P    +I+   +  AICNT +++  NQ  +K+ H       + ++     +I+S F  + V     P L    E +  +P   +                + V +  ES Q  SS      T        L N   E L   PL       +ESPDE ALV         L  RT +++++ +      + +++L  LPFDS+RK MSV+V+   + ++ +  KGADSV+   + +A+ D      +   +  +T+  +  YA  GLRTL + K+++++ EY +W       E ++ N E  + E    +E+ L L+GA G+ED+LQE VPE +E   +AGI IW+LTGDK+ETA++IAY+ +L   ++ +  ++ +S+     +MS I ++++K         SL +   +            L+I G +L   L  + L+++FL +  +C  VVCCR TP+QK EVV LV+ + +V TLAIGDGANDV+MIQ ADIGIGVSG+EG QA +ASDFA+++FK+L +L+LVHGH  Y +L+ M L  FYKN+    ++F+YQ   GFS +   D    + F+L+ T  PP+I+GV +KD S E L+  P++Y +G  S+ Y P  FW T+LD+ +QSLV F VP   Y  ++  +  FG    +  +  +  H++IES+  +  H  + IG++ + ++L   +  ++CV    CN   NPY ++   M     YL+  L+T+I+L PR + +
Sbjct:  571 DETIQNPPMETLYIIDFFIALAICNTVVVSAPNQPRQKIRHPSLGGLPIKSLE----EIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQVCESPQCSSSSACCTETEKQHGDAGLLNGKAESLPGQPLACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMV-DFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFAL-QESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSI-LSYFLFAIVFGAMCVT---CNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYR 1318          

Query:  219 PLTDESKK-----VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL 1445
            P  DE +K     VNNRIRTTKY   NF+  NLFEQF R +NL+F+F V+LN++P V AF +   ++P++ +L +  IKDG+ED R+Y  D+ +NN     Y +   ++    WKD++VGD I+LS  E IPAD+++ +S+DP G+C IET  +DGE+ LKQR V++      + ++    +   E E+ N  + +F G  F     K    L+  NL+LR   +RNT  V GIV+YAG++TK  +NN   R+KRS LE + N D+L C+ +L+I+C+   +G   +L  + K+        +  +I  + L GF  FWT II+ Q +IPI+LY+++E+VK  QI  I +D+  Y+E MD  +  +A NI EDLGQI+ +F DKTGTLT+N+M+FR  S+ G +Y  EEN  RL
Sbjct:   59 PFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPNNDLSRFRG--FLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPL-LAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRL 469          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNAT-GEISLNCKGADSVMFP---KIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWS-VFHWAICIGTLGIGFYLELFILNSLCVVLLDCNT--DNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            SESPDE ALV      G  L +R  D +I++       + Y++L TLPFD+ RK MSVI+++++    I +  KGAD+ + P   +  + S +  E+I +++  +  YA  GLRTL +  +I  E EY+ W+E   + E ++++ E  + E     E +L+L+G   +ED+LQ+ VPE +   +EAGI +W+LTGDK ETA++IAYS+RLFS +  +  I       + +++++  + I ++   S    +        F LV++  ++S  L    L E F+ +   C  V+CCR TP+QK ++V L K + + + LAIGDGANDV+MIQ AD+GIG+SG+EG QA ++SDFA+ +F++L  L+LVHGH +Y +LA+  L  FYKN ++  V+F+YQI +GFS    ID V  ++++LI T +PP++FG  D+D S E+LL  P++Y  G   K YR   FW  +LD++WQSLV+F +    Y  + + M  FG + V+ ++I    H+ +  ++W+    W++ +  L   F++   + N             D P  V   + S  + ++ + +S  + L PR ++
Sbjct:  768 SESPDELALVEAAREYGIRLLRRRFDDVIVYLRHSTSSVKYKVLHTLPFDADRKRMSVIIRESSGLKRIIVLTKGADATVIPVLSEAFSTSARGEEVIFKSQEHLTQYAKEGLRTLCLSMKIWTEEEYQGWKEKHEEAELDMMDKETMLAESTLRAEQDLELLGVTAIEDRLQDGVPECIHSLREAGIRVWVLTGDKIETAVNIAYSSRLFSPSMDLLNIGANGVRAVSDLLTEHLKRIARAYEVSADAADS-------FGLVLNASTMSYCLDPHNL-ERFVKLLRGCRSVLCCRATPLQKAQLVNLAKNHLKGKVLAIGDGANDVSMIQGADVGIGLSGQEGMQAVMSSDFAMARFRFLSNLLLVHGHWNYYRLAQTILYFFYKNAMLVFVIFWYQIFNGFSAQVPIDPVYLMVYNLIFTSVPPLLFGCLDQDASAELLLDCPRLYEQGRLGKRYRWYSFWINMLDAVWQSLVVFFICYFTYRGSNVDMWTFGHLLVTQLIIVNTFHLALFVQYWTWPMFWSMFLSVL--LFFICALLYNGFVTANWTWTNVKDPPSMVSLKSFSSLEFWMALIISVVLCLTPRYVL 1346          

Query:  237 KKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLD---NNSTNLE--EVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQH----LNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNK---IQNVIFITSNFT--------VIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            K   NRI TTKY    FI  NLFEQ  R +NL+FIF VILN I  +GAF +  +++PI F+L +T IKD  ED RRY SD+ +N+     +D     +   +W++I VGD + LS  E IPAD+L+  SSD +G+C++ET ++DGE+ LKQR  ++S+    N +  LE      NY    E     +YKF G++     G  +      L   N++LR  +++NT+ V GIV+YAG  TK  +NN   R+KRS LE   NVD+L  +  L+ +C++  +    +LR F+    +  ++FI  N +          Y    + +  FW+ IIV Q +IPI+LY+++E +K  Q+  ++ D  +Y + +DK++  +A NITE+LGQI+ +  DKTGTLT+N+M+FR  S+ G +Y
Sbjct:  102 KYCGNRISTTKYSVLTFIPKNLFEQLHRAANLYFIFIVILNMI--IGAFGKYISVLPIAFVLGITAIKDAFEDYRRYKSDQKINHSTCRVWDASQQRYRKLEWQNILVGDFVHLSHDEIIPADILLLRSSDVNGVCYVETCNLDGESNLKQRQAIRSMGKYHNANVPLEYSPAEFNYRIACEQPTTDVYKFEGRLEAIEGGPPLAREFTILAKENVLLRGCVVKNTDFVEGIVLYAGKDTKAMLNNNGPRYKRSSLEKMTNVDILWSVCTLLALCVIGAVLSGVWLRTFSTPYIVPFLVFIHPNSSYHNNNDSQYKYSPSYESWFSFWSYIIVLQVMIPISLYVSIEFIKIFQVWFMSQDRNMYYDKVDKRLQCRALNITEELGQIQYVMSDKTGTLTENQMVFRRCSVNGNDY 513          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQ--------NETVKXXXXXXXXXXXNVMSQI-----------REDIEKSLFDSKRENNEKT---------------CKHKE--FVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGE-------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVV--LLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLG 3656
            ++SPDE AL       G+    RT   + I      +   +E+L  L F++ RK MSVIVK    G+I L CKGAD ++  +I  ++ +       T   +  +A+ GLRTL +G + L+   +  W+  + K    + + E+ +  LY+ IE +L L+GA  +EDKLQ+ VPE +    EA I IW+LTGDK ETAI+IAYS RL +         +            +  N   QI           R +IE    +S+  ++ ++                +H+     LVI+G SL+  L    L+  FL +A  CN V+CCR TP+QK +VV LVK+  +  TL+IGDGANDV+MI+TA IG+G+SG+EG QA LASD++I +FKYL+RL+LVHG  SY ++A+     FYKN   +L  F+Y    G+S     D V    ++L  T LP +  G  D+D  D   L  P++YL G  +  +  R F  ++L  ++ SLVIF +P   ++N   + G+           + + +V+ +   I  ++ +W+     +  G+L + ++L  F+L     V  ++  ++   Y V   TM     +  I + + + L P +L + F +++  S F +  R   K+G
Sbjct:  508 AQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEE--THELLAILDFNNDRKRMSVIVK-GPDGKIRLYCKGADMMIMQRIHPSTSQIMR--TSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFAL-GPRLERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGSL-VLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS-FADRLRIRKKMG 1149          

Query:  237 KKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEV--EASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIY----------------DVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNIT--EDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            K  +N I+T+KY    FI  NLFEQF+R +N +F+  +IL FIP++ + +  +  +P++ +L  + IKDG +D +R+ SDRNVN R    Y       C   W ++ VGD+I++ S + + ADLL+  +S+P G+CFIETM++DGET LK R  +        +L+ + + +  E+  E  N ++ KFNGK+   +H  G     +N  N++LR  IL+NT    G+V++AG  TK+ MN+ + +FKR+ L+  LN+ ++  +  LI +C++  I C+ +           + T  +  IY                 + L  F+QF++ II+  +++PI+LY+++E+++    L I  D  +Y E+ +K +  KA+  T  E+LGQ++ +F DKTGTLT N M F   +I G +Y
Sbjct:   35 KYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRK--SYVVRNGSLCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITR-FDGEIICEPPNNKLDKFNGKLIWNNHEYG-----VNNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWE----------YQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISY 432          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQ--------NETVKXXXXXXXXXXXNVMSQI-----------REDIEKSLFDSKRENNEKT---------------CKHKE--FVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGE-------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVV--LLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLG 3656
            ++SPDE AL       G+    RT   + I      +   +E+L  L F++ RK MSVIVK    G+I L CKGAD ++  +I  ++ +       T   +  +A+ GLRTL +G + L+   +  W+  + K    + + E+ +  LY+ IE +L L+GA  +EDKLQ+ VPE +    EA I IW+LTGDK ETAI+IAYS RL +         +            +  N   QI           R +IE    +S+  ++ ++                +H+     LVI+G SL+  L    L+  FL +A  CN V+CCR TP+QK +VV LVK+  +  TL+IGDGANDV+MI+TA IG+G+SG+EG QA LASD++I +FKYL+RL+LVHG  SY ++A+     FYKN   +L  F+Y    G+S     D V    ++L  T LP +  G  D+D  D   L  P++YL G  +  +  R F  ++L  ++ SLVIF +P   ++N   + G+           + + +V+ +   I  ++ +W+     +  G+L + ++L  F+L     V  ++  ++   Y V   TM     +  I + + + L P +L + F +++  S F +  R   K+G
Sbjct:  508 AQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEE--THELLAILDFNNDRKRMSVIVK-GPDGKIRLYCKGADMMIMQRIHPSTSQIMR--TSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFAL-GPRLERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGSL-VLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS-FADRLRIRKKMG 1149          

Query:  237 KKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEV--EASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIY----------------DVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNIT--EDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            K  +N I+T+KY    FI  NLFEQF+R +N +F+  +IL FIP++ + +  +  +P++ +L  + IKDG +D +R+ SDRNVN R    Y       C   W ++ VGD+I++ S + + ADLL+  +S+P G+CFIETM++DGET LK R  +        +L+ + + +  E+  E  N ++ KFNGK+   +H  G     +N  N++LR  IL+NT    G+V++AG  TK+ MN+ + +FKR+ L+  LN+ ++  +  LI +C++  I C+ +           + T  +  IY                 + L  F+QF++ II+  +++PI+LY+++E+++    L I  D  +Y E+ +K +  KA+  T  E+LGQ++ +F DKTGTLT N M F   +I G +Y
Sbjct:   35 KYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRK--SYVVRNGSLCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITR-FDGEIICEPPNNKLDKFNGKLIWNNHEYG-----VNNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWE----------YQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISY 432          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQ--------NETVKXXXXXXXXXXXNVMSQI-----------REDIEKSLFDSKRENNEKT---------------CKHKE--FVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGE-------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVV--LLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLG 3656
            ++SPDE AL       G+    RT   + I      +   +E+L  L F++ RK MSVIVK    G+I L CKGAD ++  +I  ++ +       T   +  +A+ GLRTL +G + L+   +  W+  + K    + + E+ +  LY+ IE +L L+GA  +EDKLQ+ VPE +    EA I IW+LTGDK ETAI+IAYS RL +         +            +  N   QI           R +IE    +S+  ++ ++                +H+     LVI+G SL+  L    L+  FL +A  CN V+CCR TP+QK +VV LVK+  +  TL+IGDGANDV+MI+TA IG+G+SG+EG QA LASD++I +FKYL+RL+LVHG  SY ++A+     FYKN   +L  F+Y    G+S     D V    ++L  T LP +  G  D+D  D   L  P++YL G  +  +  R F  ++L  ++ SLVIF +P   ++N   + G+           + + +V+ +   I  ++ +W+     +  G+L + ++L  F+L     V  ++  ++   Y V   TM     +  I + + + L P +L + F +++  S F +  R   K+G
Sbjct:  543 AQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEE--THELLAILDFNNDRKRMSVIVK-GPDGKIRLYCKGADMMIMQRIHPSTSQIMR--TSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFAL-GPRLERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGSL-VLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS-FADRLRIRKKMG 1184          

Query:  237 KKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEV--EASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIY----------------DVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNIT--EDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            K  +N I+T+KY    FI  NLFEQF+R +N +F+  +IL FIP++ + +  +  +P++ +L  + IKDG +D +R+ SDRNVN R    Y       C   W ++ VGD+I++ S + + ADLL+  +S+P G+CFIETM++DGET LK R  +        +L+ + + +  E+  E  N ++ KFNGK+   +H  G     +N  N++LR  IL+NT    G+V++AG  TK+ MN+ + +FKR+ L+  LN+ ++  +  LI +C++  I C+ +           + T  +  IY                 + L  F+QF++ II+  +++PI+LY+++E+++    L I  D  +Y E+ +K +  KA+  T  E+LGQ++ +F DKTGTLT N M F   +I G +Y
Sbjct:   70 KYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRK--SYVVRNGSLCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITR-FDGEIICEPPNNKLDKFNGKLIWNNHEYG-----VNNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWE----------YQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISY 467          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQ--------NETVKXXXXXXXXXXXNVMSQI-----------REDIEKSLFDSKRENNEKT---------------CKHKE--FVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGE-------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVV--LLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLG 3656
            ++SPDE AL       G+    RT   + I      +   +E+L  L F++ RK MSVIVK    G+I L CKGAD ++  +I  ++ +       T   +  +A+ GLRTL +G + L+   +  W+  + K    + + E+ +  LY+ IE +L L+GA  +EDKLQ+ VPE +    EA I IW+LTGDK ETAI+IAYS RL +         +            +  N   QI           R +IE    +S+  ++ ++                +H+     LVI+G SL+  L    L+  FL +A  CN V+CCR TP+QK +VV LVK+  +  TL+IGDGANDV+MI+TA IG+G+SG+EG QA LASD++I +FKYL+RL+LVHG  SY ++A+     FYKN   +L  F+Y    G+S     D V    ++L  T LP +  G  D+D  D   L  P++YL G  +  +  R F  ++L  ++ SLVIF +P   ++N   + G+           + + +V+ +   I  ++ +W+     +  G+L + ++L  F+L     V  ++  ++   Y V   TM     +  I + + + L P +L + F +++  S F +  R   K+G
Sbjct:  543 AQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEE--THELLAILDFNNDRKRMSVIVK-GPDGKIRLYCKGADMMIMQRIHPSTSQIMR--TSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFAL-GPRLERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGSL-VLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS-FADRLRIRKKMG 1184          

Query:  237 KKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEV--EASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIY----------------DVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNIT--EDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            K  +N I+T+KY    FI  NLFEQF+R +N +F+  +IL FIP++ + +  +  +P++ +L  + IKDG +D +R+ SDRNVN R    Y       C   W ++ VGD+I++ S + + ADLL+  +S+P G+CFIETM++DGET LK R  +        +L+ + + +  E+  E  N ++ KFNGK+   +H  G     +N  N++LR  IL+NT    G+V++AG  TK+ MN+ + +FKR+ L+  LN+ ++  +  LI +C++  I C+ +           + T  +  IY                 + L  F+QF++ II+  +++PI+LY+++E+++    L I  D  +Y E+ +K +  KA+  T  E+LGQ++ +F DKTGTLT N M F   +I G +Y
Sbjct:   70 KYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRK--SYVVRNGSLCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITR-FDGEIICEPPNNKLDKFNGKLIWNNHEYG-----VNNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWE----------YQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISY 467          

Query: 1830 PLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEII--NQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            PL  +ESPDE ALV         L  R+ +++++          YEILK LPFDS RKCMS++V+   + EI L  KGADS + P ++  S    E I   QT+  +  YA  GLR LVM KR LN  +Y  W     ++E +L N E  +++ +  +ESNL L+GA G+ED+LQ+ VPE +     AGI++W+LTGDK ETAI+IAYS +LF+Q   +  ++  S       ++    D+E     S     + + + K+  LV+DG +L+ IL    +L   FL ++  C  V+CCR TP+QK  +V +VK+   +RTLAIGDGANDV+MIQ AD+G+G+SG+EG QA +A+DF + +F+YL+RL+L HG+  YD+L+RM L  FYKN     ++F+YQ+  GFS    +DQ+  ++++LI T LPP+  GV+DK  ++++LL NP +Y  G     YRP DFW  +LD+L+QSLVIF V    Y  +++ + EFG    +  + A   H  IE R W+V H    + +LG  FYL   + +S+C   ++C    + Y V+    +    +L+I LST +++ PRLL+
Sbjct:  874 PLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQ-SLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLG-SFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLL 1458          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYF----EVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLR-------------LCCDSENEELHN-------NPH---ILQLLLLSAICNTTIIAKSNQRE 1556
            V N+IRTTKY   +FI  NL EQF R +NL+FIF V+LN++PE+ AF +  A+IP+LF+L VT +KD  ED RR  SD+ +NN     YD     +   KW+++ VGD++ LS+ E +PAD+L+  +SDP G+C+I+T D+DGET LK+R V++  +     ++ +F    F    E +A   ++Y+F+G +  H  G+ V  ++   L+LR++ L+NT+ + GIV+YAG++TK  +NN   R+KRS +E Q+N+D++ C+ IL+I+C++  IGC  +L  F          +  T      ++    FWT I++ Q +IP++LY+T+EL K  Q+ HI N++ L+D   +K+ + +A NITE+LGQI+ +F DKTGTLT+N+MIFR   + G +Y    ++L              +  D+ N ++          PH   I + L++ AICNT I+  +  R+
Sbjct:  251 VGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFE----EMQSIFVPSKFVSRVEADAPTTKLYRFHGALI-HPTGERVP-ISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLT----ANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRD 705          

Query: 1830 PLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEII--NQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            PL  +ESPDE ALV         L  R+ +++++          YEILK LPFDS RKCMS++V+   + EI L  KGADS + P ++  S    E I   QT+  +  YA  GLR LVM KR LN  +Y  W     ++E +L N E  +++ +  +ESNL L+GA G+ED+LQ+ VPE +     AGI++W+LTGDK ETAI+IAYS +LF+Q   +  ++  S       ++    D+E     S     + + + K+  LV+DG +L+ IL    +L   FL ++  C  V+CCR TP+QK  +V +VK+   +RTLAIGDGANDV+MIQ AD+G+G+SG+EG QA +A+DF + +F+YL+RL+L HG+  YD+L+RM L  FYKN     ++F+YQ+  GFS    +DQ+  ++++LI T LPP+  GV+DK  ++++LL NP +Y  G     YRP DFW  +LD+L+QSLVIF V    Y  +++ + EFG    +  + A   H  IE R W+V H    + +LG  FYL   + +S+C   ++C    + Y V+    +    +L+I LST +++ PRLL+
Sbjct:  874 PLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQ-SLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLG-SFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLL 1458          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYF----EVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLR-------------LCCDSENEELHN-------NPH---ILQLLLLSAICNTTIIAKSNQRE 1556
            V N+IRTTKY   +FI  NL EQF R +NL+FIF V+LN++PE+ AF +  A+IP+LF+L VT +KD  ED RR  SD+ +NN     YD     +   KW+++ VGD++ LS+ E +PAD+L+  +SDP G+C+I+T D+DGET LK+R V++  +     ++ +F    F    E +A   ++Y+F+G +  H  G+ V  ++   L+LR++ L+NT+ + GIV+YAG++TK  +NN   R+KRS +E Q+N+D++ C+ IL+I+C++  IGC  +L  F          +  T      ++    FWT I++ Q +IP++LY+T+EL K  Q+ HI N++ L+D   +K+ + +A NITE+LGQI+ +F DKTGTLT+N+MIFR   + G +Y    ++L              +  D+ N ++          PH   I + L++ AICNT I+  +  R+
Sbjct:  251 VGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFE----EMQSIFVPSKFVSRVEADAPTTKLYRFHGALI-HPTGERVP-ISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLT----ANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRD 705          

Query: 1830 PLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEII--NQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            PL  +ESPDE ALV         L  R+ +++++          YEILK LPFDS RKCMS++V+   + EI L  KGADS + P ++  S    E I   QT+  +  YA  GLR LVM KR LN  +Y  W     ++E +L N E  +++ +  +ESNL L+GA G+ED+LQ+ VPE +     AGI++W+LTGDK ETAI+IAYS +LF+Q   +  ++  S       ++    D+E     S     + + + K+  LV+DG +L+ IL    +L   FL ++  C  V+CCR TP+QK  +V +VK+   +RTLAIGDGANDV+MIQ AD+G+G+SG+EG QA +A+DF + +F+YL+RL+L HG+  YD+L+RM L  FYKN     ++F+YQ+  GFS    +DQ+  ++++LI T LPP+  GV+DK  ++++LL NP +Y  G     YRP DFW  +LD+L+QSLVIF V    Y  +++ + EFG    +  + A   H  IE R W+V H    + +LG  FYL   + +S+C   ++C    + Y V+    +    +L+I LST +++ PRLL+
Sbjct:  874 PLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQ-SLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLG-SFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLL 1458          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYF----EVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLR-------------LCCDSENEELHN-------NPH---ILQLLLLSAICNTTIIAKSNQRE 1556
            V N+IRTTKY   +FI  NL EQF R +NL+FIF V+LN++PE+ AF +  A+IP+LF+L VT +KD  ED RR  SD+ +NN     YD     +   KW+++ VGD++ LS+ E +PAD+L+  +SDP G+C+I+T D+DGET LK+R V++  +     ++ +F    F    E +A   ++Y+F+G +  H  G+ V  ++   L+LR++ L+NT+ + GIV+YAG++TK  +NN   R+KRS +E Q+N+D++ C+ IL+I+C++  IGC  +L  F          +  T      ++    FWT I++ Q +IP++LY+T+EL K  Q+ HI N++ L+D   +K+ + +A NITE+LGQI+ +F DKTGTLT+N+MIFR   + G +Y    ++L              +  D+ N ++          PH   I + L++ AICNT I+  +  R+
Sbjct:  251 VGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFE----EMQSIFVPSKFVSRVEADAPTTKLYRFHGALI-HPTGERVP-ISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLT----ANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRD 705          

Query: 1830 PLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEII--NQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            PL  +ESPDE ALV         L  R+ +++++          YEILK LPFDS RKCMS++V+   + EI L  KGADS + P ++  S    E I   QT+  +  YA  GLR LVM KR LN  +Y  W     ++E +L N E  +++ +  +ESNL L+GA G+ED+LQ+ VPE +     AGI++W+LTGDK ETAI+IAYS +LF+Q   +  ++  S       ++    D+E     S     + + + K+  LV+DG +L+ IL    +L   FL ++  C  V+CCR TP+QK  +V +VK+   +RTLAIGDGANDV+MIQ AD+G+G+SG+EG QA +A+DF + +F+YL+RL+L HG+  YD+L+RM L  FYKN     ++F+YQ+  GFS    +DQ+  ++++LI T LPP+  GV+DK  ++++LL NP +Y  G     YRP DFW  +LD+L+QSLVIF V    Y  +++ + EFG    +  + A   H  IE R W+V H    + +LG  FYL   + +S+C   ++C    + Y V+    +    +L+I LST +++ PRLL+
Sbjct:  874 PLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQ-SLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLG-SFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLL 1458          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYF----EVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLR-------------LCCDSENEELHN-------NPH---ILQLLLLSAICNTTIIAKSNQRE 1556
            V N+IRTTKY   +FI  NL EQF R +NL+FIF V+LN++PE+ AF +  A+IP+LF+L VT +KD  ED RR  SD+ +NN     YD     +   KW+++ VGD++ LS+ E +PAD+L+  +SDP G+C+I+T D+DGET LK+R V++  +     ++ +F    F    E +A   ++Y+F+G +  H  G+ V  ++   L+LR++ L+NT+ + GIV+YAG++TK  +NN   R+KRS +E Q+N+D++ C+ IL+I+C++  IGC  +L  F          +  T      ++    FWT I++ Q +IP++LY+T+EL K  Q+ HI N++ L+D   +K+ + +A NITE+LGQI+ +F DKTGTLT+N+MIFR   + G +Y    ++L              +  D+ N ++          PH   I + L++ AICNT I+  +  R+
Sbjct:  251 VGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFE----EMQSIFVPSKFVSRVEADAPTTKLYRFHGALI-HPTGERVP-ISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLT----ANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRD 705          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCY 3281
            + SPDE ALV      G+    RT   + I     RK   YE+L  L F S RK MS+IV+     +I L CKGAD+V++ ++ A   + F    QT   +  +AS+GLRTL +    +  + Y++W +T  K    L N E+++++  +LIE+NL L+GA  +ED+LQ+ VPE +    +AGI IW+LTGDK+ETAI+I YS RL S +  +              +   RE I +   + K      + K     LVIDG +L   L+ D L+ +F  +   C  V+CCR +P+QK EVV +V +     TLAIGDGANDV MIQ A++GIG+SG EG QA  ASD++I +F+YL+RL+LVHG  +Y +++++ L  FYKN+ + ++  ++ + SG+S     ++ T  +++++ T +PP   G+++K  + E ++  P +Y T  N+K++  + FW  I ++L  S+ +F +P   Y
Sbjct:  480 AASPDERALVEGAQKFGYIFDTRTPKYVEINALGVRK--RYEVLNVLEFTSSRKRMSLIVR-TPENKIKLFCKGADTVIYERL-APQGQAFR--EQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDI-------IILNEESLDATREVIHRHYGEFK----SSSAKDANVALVIDGTTLKYALSCD-LRNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAY 941          

Query:  234 SKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDN--NSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHN-------NPHILQLLLLSAICNTTI 1532
            +K  NNRI T KY F +F+   LFEQF+RYSN FF+   IL  IPEV    + T ++P++FIL V+ IK+ +ED++R+ +D  +N+R + R D     +C  +W +++VGD+IK+      PADL++  SS+P  MCFIET ++DGET LK R  + +      + +L+ +      E E  N+ +Y+FNG +     GK    L    ++ R  ILRNT  V GIV+Y+G +TK+  N+  A  KRS ++   N  +LM   ILI +CI++G+   F+ R  ++    + +T   T      L  F       I++ ++IPI+L +TLELV+  Q + I  D+ +Y E  +     +  N+ E+LG +K +F DKTGTLT N M F+  SI G  Y  E          E++ + N       +  I + L L ++C+T I
Sbjct:   44 TKYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRSIERLDS--GSWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGR--IECELPNRHLYEFNGVL--RETGKPPAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDWYLGLTDFKTKSLGYNLLTF------FILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVYTAERT------PEESQLVQNILGRHETSAVIEEFLELLSVCHTVI 467          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPK---IIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETV----KXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKT----CKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPRL---LIKGFLMES 3608
            + SPDE AL+      GF + +RT  + +         + +E+L  L FDS R+ MS+IV+   T EI +  KGADS +  K   + +       I  +T+ D+  YA +GLRTL   K++++E E+K W  +  +    +   E  + E  + IE+NL L+GA G+ED+LQE VPE ++  + AG+ +W+LTGDK ETA++IAYS +L    + V           +  + + +S++R        D +      T           LVIDG +L++ L+ D L E+F+ +   C  V+CCR TP+QK  VV ++++   V TLA+GDGANDVNMIQ AD+GIGVSG+EG QA +ASDFAIT+FK+L+RL+LVHGH  Y +LA M +  FYKN+    ++F+YQ   GFS +  ID    + F+L  T  PPI+FG+ DK+ SD  LL+ P++Y  G +S+ YR   FW  ILD+ +QSLV F +P   Y +++I +  FG    +  +  +  H+ IE + W+V HW I +G++ + F L L   +++C+    CN   +PY ++H  M+    YL+  L+T ++L PR    ++KG L  S
Sbjct:  654 AHSPDEAALIHAAKAYGFTMVERT-PRYVTVKLPNETLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVESAAKRIAVRTQKDLDMYARDGLRTLCFAKKVISEQEFKAWFTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMALSED-LVEQFVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLVYFILTL-AYSAICI---SCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPS 1251          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFE----VEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC----DSENEE--LHNNPHILQLLLLSAI----------CNTTIIAKSNQREK 1559
             N I+T KYR ++F+ +NLFEQF R +N++F+   ILNFIP V AF    A+IPI  IL +T +KDG ED RRY +D+ +NN P   + + L  F   +WKD+ VGD +K+ S E IPAD+L+ ++SDP+G+C +ET ++DGET LKQR V+       + L E F+   F+     E  N  +  F G  F  R  K        +L+LR   +RNT++  GIV+YAG++TK  +NN   R+KRS +E ++N D+L C+ +L  +C++  +G + +L  F+ + + I   SN   I    L GF  F+T II+ Q +IP++LY+++ELVK  QI  IT D  LYD+ +D ++  +A NITEDLGQI+ +F DKTGTLT+N+M+F+  +I G  Y  EEN  RL       +E EE  ++    +  L  L  +           NT + A S +R K
Sbjct:   48 GNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGF----STLGEPFQPQTFDSTVVCENPNNNLNLFKG--FIERPDKRRSGFGIDSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFSTMPSYIVPDSNGNYISSA-LAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEENAARLAVINGGGNEEEEVTIYQKTKLPPLFPLEELQDDHTGHKNHANTQVAAASRRRSK 498          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPK---IIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETV----KXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKT----CKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPRL---LIKGFLMES 3608
            + SPDE AL+      GF + +RT  + +         + +E+L  L FDS R+ MS+IV+   T EI +  KGADS +  K   + +       I  +T+ D+  YA +GLRTL   K++++E E+K W  +  +    +   E  + E  + IE+NL L+GA G+ED+LQE VPE ++  + AG+ +W+LTGDK ETA++IAYS +L    + V           +  + + +S++R        D +      T           LVIDG +L++ L+ D L E+F+ +   C  V+CCR TP+QK  VV ++++   V TLA+GDGANDVNMIQ AD+GIGVSG+EG QA +ASDFAIT+FK+L+RL+LVHGH  Y +LA M +  FYKN+    ++F+YQ   GFS +  ID    + F+L  T  PPI+FG+ DK+ SD  LL+ P++Y  G +S+ YR   FW  ILD+ +QSLV F +P   Y +++I +  FG    +  +  +  H+ IE + W+V HW I +G++ + F L L   +++C+    CN   +PY ++H  M+    YL+  L+T ++L PR    ++KG L  S
Sbjct:  654 AHSPDEAALIHAAKAYGFTMVERT-PRYVTVKLPNETLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVESAAKRIAVRTQKDLDMYARDGLRTLCFAKKVISEQEFKAWFTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMALSED-LVEQFVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLVYFILTL-AYSAICI---SCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPS 1251          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFE----VEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC----DSENEE--LHNNPHILQLLLLSAI----------CNTTIIAKSNQREK 1559
             N I+T KYR ++F+ +NLFEQF R +N++F+   ILNFIP V AF    A+IPI  IL +T +KDG ED RRY +D+ +NN P   + + L  F   +WKD+ VGD +K+ S E IPAD+L+ ++SDP+G+C +ET ++DGET LKQR V+       + L E F+   F+     E  N  +  F G  F  R  K        +L+LR   +RNT++  GIV+YAG++TK  +NN   R+KRS +E ++N D+L C+ +L  +C++  +G + +L  F+ + + I   SN   I    L GF  F+T II+ Q +IP++LY+++ELVK  QI  IT D  LYD+ +D ++  +A NITEDLGQI+ +F DKTGTLT+N+M+F+  +I G  Y  EEN  RL       +E EE  ++    +  L  L  +           NT + A S +R K
Sbjct:   48 GNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGF----STLGEPFQPQTFDSTVVCENPNNNLNLFKG--FIERPDKRRSGFGIDSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFSTMPSYIVPDSNGNYISSA-LAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEENAARLAVINGGGNEEEEVTIYQKTKLPPLFPLEELQDDHTGHKNHANTQVAAASRRRSK 498          

Query: 1851 PDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF--EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
            PDE ALV+     G  L  R+ +++++        +   +L  LPF S RK MSV+V+   TGE+ +  KGAD+V+  ++   ++ DF  E++  T+  +  YA  GLRTL + K++L E EY+ W +     E ++ N E  + E  + +E++L L+GA G+ D+LQE VPE +E  +EAGI +W+LTGDK+ETAI+IA++ +L    + +   +C+S+      + +++ ++++    +K +  E  C   + VLVIDG +L   L   EL+  FL +   C  V+CCR TP+QK +VV LV+   EV TLAIGDGANDV+MIQ AD+G+G+SG+EG QA ++SDFAI++FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F+YQ   GFS S   +    + F+L+ T +PP+++GV DKD S E LL  P +Y +G NS+ Y P  FW  ILD+ +QSLV F +P   Y  ++I +  F        ++ +  H +IESR  +  H ++ I + G+ +Y  + + +  CV    CN+  NPY +    MS    YL+  L+T ++L PR+L + F
Sbjct:  586 PDEAALVQAAKAYGCTLLGRSPEQVLV-AVPGTGPLSISLLHVLPFHSARKRMSVVVRHPLTGEVVVYTKGADNVIM-ELAKQAEDDFSREVMELTQRHLDQYAREGLRTLCVAKKVLGEQEYEAWMKRHEYAETSIENREELLLESAERLETDLTLLGATGIVDRLQEEVPETIEALQEAGIKVWVLTGDKQETAINIAFACKLLRPTDHILMANCDSKEACEARLQELQLEVQQV---TKADEPEGDCI-SDCVLVIDGRTLDYAL-QKELQGAFLDLTCCCRSVICCRSTPLQKSQVVRLVRDKLEVMTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMSSDFAISRFKFLRKLILVHGHWCYARLANMILYFFYKNVMYVNLLFWYQFFCGFSGSTMTNSWVLIFFNLLFTSVPPLVYGVLDKDVSAETLLKLPDLYKSGQNSQAYLPTTFWLNILDAFYQSLVCFFIPYFAYAGSDIGVFSFASPINGSALLIILLHQVIESRTLTWIHASLLIFS-GLFYYAFVLLFSITCVT---CNSPTNPYGIETKMMSEPLYYLVCVLTTVLALLPRMLSRAF 1159          

Query:  444 GVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNY--YFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL 1445
             +ED RRY  D+ +NN     Y      +   +W ++ VGD+++L   E IPAD+++ +SSD +G+C IET ++DGET LKQR V++ L       E V +N+    E E  N  + +F G  F    GK    L+  NL+LR   +RNT  V GIV+YAG++TK   NN   R+KRS LE +LN+D+L  + +L+++C +  IG   +L   +++++ IF+  + T      L  F  FWT IIV Q +IPI+LY+++E+VK  QI  I NDL LY+  +D  +  +A NITEDLGQI+ +F DKTGTLT+N M+FR  ++ G  Y   EN + L
Sbjct:    2 AMEDYRRYRYDKKINNTLTHVYSGKQQRYVERRWAEVCVGDLVRLCCNEIIPADMVLLHSSDSNGVCHIETANLDGETNLKQRQVVRDLTQQGA--EFVPENFSSRIECENPNNDLRRFRG--FMEHPGKVRVGLHSENLLLRSCTVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNLDVLWSVALLLLMCFIAAIGHGLWL---SELEDPIFMIPDNT---HPALAAFYMFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIQNDLDLYNPVLDTGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVAGTEYPHHENAVSL 327          

Query: 1851 PDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF--EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
            PDE ALV+     G  L  R+ +++++        +   +L  LPF S RK MSV+V+   TGE+ +  KGAD+V+  ++   ++ DF  E++  T+  +  YA  GLRTL + K++L E EY+ W +     E ++ N E  + E  + +E++L L+GA G+ D+LQE VPE +E  +EAGI +W+LTGDK+ETAI+IA++ +L    + +   +C+S+      + +++ ++++    +K +  E  C   + VLVIDG +L   L   EL+  FL +   C  V+CCR TP+QK +VV LV+   EV TLAIGDGANDV+MIQ AD+G+G+SG+EG QA ++SDFAI++FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F+YQ   GFS S   +    + F+L+ T +PP+++GV DKD S E LL  P +Y +G NS+ Y P  FW  ILD+ +QSLV F +P   Y  ++I +  F        ++ +  H +IESR  +  H ++ I + G+ +Y  + + +  CV    CN+  NPY +    MS    YL+  L+T ++L PR+L + F
Sbjct:  719 PDEAALVQAAKAYGCTLLGRSPEQVLV-AVPGTGPLSISLLHVLPFHSARKRMSVVVRHPLTGEVVVYTKGADNVIM-ELAKQAEDDFSREVMELTQRHLDQYAREGLRTLCVAKKVLGEQEYEAWMKRHEYAETSIENREELLLESAERLETDLTLLGATGIVDRLQEEVPETIEALQEAGIKVWVLTGDKQETAINIAFACKLLRPTDHILMANCDSKEACEARLQELQLEVQQV---TKADEPEGDCI-SDCVLVIDGRTLDYAL-QKELQGAFLDLTCCCRSVICCRSTPLQKSQVVRLVRDKLEVMTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMSSDFAISRFKFLRKLILVHGHWCYARLANMILYFFYKNVMYVNLLFWYQFFCGFSGSTMTNSWVLIFFNLLFTSVPPLVYGVLDKDVSAETLLKLPDLYKSGQNSQAYLPTTFWLNILDAFYQSLVCFFIPYFAYAGSDIGVFSFASPINGSALLIILLHQVIESRTLTWIHASLLIFS-GLFYYAFVLLFSITCVT---CNSPTNPYGIETKMMSEPLYYLVCVLTTVLALLPRMLSRAF 1292          

Query:  249 NRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNY--YFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL 1445
            N++RTTKY F +FI  NLFEQ  R++N++F+F   LNF+P V AF    +IIPI+F++ +T IKD  ED RR  SD+ VNNR    YD+    +   +W ++ VGD+++L   E IPAD+++ +SSD +G+C IET ++DGET LKQR V++ L       E V +N+    E E  N  + +F G  F    GK    L+  NL+LR   +RNT  V GIV+YAG++TK   NN   R+KRS LE +LN+D+L  + +L+++C +  IG   +L   +++++ IF+  + T      L  F  FWT IIV Q +IPI+LY+++E+VK  QI  I NDL LY+  +D  +  +A NITEDLGQI+ +F DKTGTLT+N M+FR  ++ G  Y   EN + L
Sbjct:   70 NKVRTTKYTFLSFIPKNLFEQLHRFANVYFVFLSALNFVPIVNAFQPEISIIPIIFVMSITAIKDLWEDQRRRKSDQQVNNRFCDVYDRKQQRYVERRWAEVCVGDLVRLCCNEIIPADMVLLHSSDSNGVCHIETANLDGETNLKQRQVVRDLTQQGA--EFVPENFSSRIECENPNNDLRRFRG--FMEHPGKVRVGLHSENLLLRSCTVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNLDVLWSVALLLLMCFIAAIGHGLWL---SELEDPIFMIPDNT---HPALAAFYMFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIQNDLDLYNPVLDTGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVAGTEYPHHENAVSL 460          

Query: 1851 PDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF--EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
            PDE ALV+     G  L  R+ +++++        +   +L  LPF S RK MSV+V+   TGE+ +  KGAD+V+  ++   ++ DF  E++  T+  +  YA  GLRTL + K++L E EY+ W +     E ++ N E  + E  + +E++L L+GA G+ D+LQE VPE +E  +EAGI +W+LTGDK+ETAI+IA++ +L    + +   +C+S+      + +++ ++++    +K +  E  C   + VLVIDG +L   L   EL+  FL +   C  V+CCR TP+QK +VV LV+   EV TLAIGDGANDV+MIQ AD+G+G+SG+EG QA ++SDFAI++FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F+YQ   GFS S   +    + F+L+ T +PP+++GV DKD S E LL  P +Y +G NS+ Y P  FW  ILD+ +QSLV F +P   Y  ++I +  F        ++ +  H +IESR  +  H ++ I + G+ +Y  + + +  CV    CN+  NPY +    MS    YL+  L+T ++L PR+L + F
Sbjct:  723 PDEAALVQAAKAYGCTLLGRSPEQVLV-AVPGTGPLSISLLHVLPFHSARKRMSVVVRHPLTGEVVVYTKGADNVIM-ELAKQAEDDFSREVMELTQRHLDQYAREGLRTLCVAKKVLGEQEYEAWMKRHEYAETSIENREELLLESAERLETDLTLLGATGIVDRLQEEVPETIEALQEAGIKVWVLTGDKQETAINIAFACKLLRPTDHILMANCDSKEACEARLQELQLEVQQV---TKADEPEGDCI-SDCVLVIDGRTLDYAL-QKELQGAFLDLTCCCRSVICCRSTPLQKSQVVRLVRDKLEVMTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMSSDFAISRFKFLRKLILVHGHWCYARLANMILYFFYKNVMYVNLLFWYQFFCGFSGSTMTNSWVLIFFNLLFTSVPPLVYGVLDKDVSAETLLKLPDLYKSGQNSQAYLPTTFWLNILDAFYQSLVCFFIPYFAYAGSDIGVFSFASPINGSALLIILLHQVIESRTLTWIHASLLIFS-GLFYYAFVLLFSITCVT---CNSPTNPYGIETKMMSEPLYYLVCVLTTVLALLPRMLSRAF 1296          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL 1445
            NN IRTTKY   +FI +NLF+QF R +NL+F+F V+LN++P V AF +   +IP+  +L V   KD +ED RRY  D+ +NN     Y      +   +W ++ VGD+++L   E IPAD+++ +SSD +G+C IET ++DGET LKQR V++ L            +   E E  N  + +F G  F    GK    L+  NL+LR   +RNT  V GIV+YAG++TK   NN   R+KRS LE +LN+D+L  + +L+++C +  IG   +L   +++++ IF+  + T      L  F  FWT IIV Q +IPI+LY+++E+VK  QI  I NDL LY+  +D  +  +A NITEDLGQI+ +F DKTGTLT+N M+FR  ++ G  Y   EN + L
Sbjct:   73 NNSIRTTKYTLISFIPMNLFQQFHRAANLYFLFLVLLNWVPAVEAFQKEITMIPLAVVLTVIAFKDAMEDYRRYRYDKKINNTLTHVYSGKQQRYVERRWAEVCVGDLVRLCCNEIIPADMVLLHSSDSNGVCHIETANLDGETNLKQRQVVRDLTQQGAEFVPENFSSRIECENPNNDLRRFRG--FMEHPGKVRVGLHSENLLLRSCTVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNLDVLWSVALLLLMCFIAAIGHGLWL---SELEDPIFMIPDNT---HPALAAFYMFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIQNDLDLYNPVLDTGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVAGTEYPHHENAVSL 464          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNN---RPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDH----RIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEEN---------------DLRLCC--------------DSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFF-----------------DYGVXXXXXXXXXXXXXDTDPIPKDLIKAV--FEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLIL---SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFP----KIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            NNRI+TTKY   NFI  NLFEQF R +NL+F+F V LN++P V AF +   ++P++ +L +  IKDG+ED R+Y  D+ +NN   +   R +K   E C   WKD++VG  I+L   E IPAD+++ +SSDP G+C IET  +DGET LKQR V+K    +     E F     + E     I  F G   DH    +IG S Q     NL+LR  I+RNT  V GIV+YAG++TK  +NN   R+KRS LE +LN D+L  + +LI +C+   IG   +L GF +   +  I           L GF  FWT II+ Q +IPI+LY+++E+VK  QI  I ND   Y E  D  I+ +A NI EDLGQ++ +F DKTGTLT+N+M+FR  SI G  Y  E N               D RL                ++E+  L  + +I+   L  AICNT +++  NQ  +K+       T + ++       Q F                  + G +   +       +   P  +   K++   + A SL S +      +   NF       ++ +   L   +ESPDE ALV         L  RT D++ +   F    + +++L  LPFDS+RK MSVI++   T ++ +  KGADS +       +I    K+ +++ Q   D   YA  GLRTL + K+++ ++EY +W ++    E ++ N E  + E    +E+ L L+GA G+ED+LQE VP+ +E  ++AGINIW+LTGDK+ETA++IAY+ RL   ++ +  ++        N  S  ++D              K+  H  F LVIDG +L + +  + L+ +FL +   C  V+CCR TP+QK +VV LV+   +V  LAIGDGANDV+MIQ ADIG+G+SG+EG QA ++SDFA++ FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F+YQ   GFS +   D    ++F+L+ T +PPII+G+ DKD S E L A P++Y +G  S+ YR   FW TILD+ +QSL  F +P   Y  +++ +  FG   ++  +  +  H++IES+  +  HW +   ++   F   L    +   V ++CN   NPY ++   +     YL+  LS  I+L PR
Sbjct:   45 NNRIQTTKYTLLNFIPRNLFEQFHRAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEKKYKESC---WKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQVVKGYSMDDEFDPEKFSGR-IQCENPTSDISSFKG-FLDHPNKEKIGLSKQ-----NLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPE-SPIFSIPEPGGQHTSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANGKVLFTKYTEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETS-YIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSNFGSKLSFFTRGKLASPTAELADKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAESPDEAALVHAARAYNCTLQSRTPDQVTVELGFIGP-LTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLITDAVITMVKKNIQMLTQKHLD--DYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLLEHSDKLFNLNEIDSLGKPNAFSSGQQD--------------KSGLH--FGLVIDGGTLEIAM-HESLQSKFLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYIGSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWIVMGASIAAYFAFSL----AFGAVCINCNPPANPYWIVQNHVRDPAFYLVCLLSIFIALLPR 1182          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRY--SNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNN---RPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDH----RIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEEND----LRLCCDSENEELHN--------------------------NP-----------------HILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFF-----------------DYGVXXXXXXXXXXXXXDTDPIPKDLIKAV--FEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLIL---SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSD----KDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            NNRI+TTKY   NFI  NLFEQF R+  +NL+F+F V LN++P V AF +   ++P++ +L +  IKDG+ED R+Y  D+ +NN   +   R +K   E C   WKD++VG  I+L   E IPAD+++ +SSDP G+C IET  +DGET LKQR V+K     S    E F     + E     I  F G   DH    +IG S Q     NL+LR  I+RNT  V GIV+YAG++TK  +NN   R+KRS LE +LN D+L  + +LI +C+   IG   +L GF +   +  I           L GF  FWT II+ Q +IPI+LY+++E+VK  QI  I ND   Y E  D  I+ +A NI EDLGQ++ +F DKTGTLT+N+M+FR  SI G  Y  E N      R C     + +H+                          NP                 +I+   L  AICNT +++  NQ  +K+       T + ++       Q F                  + G +   +       +   P  +   K++   + A SL S +      +   NF       ++ +   L   +ESPDE ALV         L  RT D++ +   F    + +++L  LPFDS+RK MSVI++   T ++ +  KGADS +   I   S+    K+ +++ Q   D   YA  GLRTL + K+++ ++EY +W ++    E ++ N E  + E    +E+ L L+GA G+ED+LQE VP+ +E  ++AGINIW+LTGDK+ETA++IAY+ RL   ++ +  ++        N  S  ++D              K+  H  F LVIDG +L + +  + L+ +FL +   C  V+CCR TP+QK +VV LV+   +V  LAIGDGANDV+MIQ ADIG+G+SG+EG QA ++SDFA++ FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F+YQ   GFS +   D    ++F+L+ T +PPII+G+ DKD S E L A P++Y +G  S+ YR   FW TILD+ +QSL  F +P   Y  +++ +  FG   ++  +  +  H++IES+  +  HW +   ++   F   L    +   V ++CN   NPY ++   +     YL+  LS  I+L PR
Sbjct:   63 NNRIQTTKYTLLNFIPRNLFEQFHRWVAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEKKYKESC---WKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQVVKGY---SMFDPEKFSGR-IQCENPTSDISSFKG-FLDHPNKEKIGLSKQ-----NLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPE-SPIFSIPEPGGQHTSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANGKVLVYRRCHVPHIQHMHSEWLYVFSCQEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETSYIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSNFGSKLSFFTRGKLASPTAELADKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAESPDEAALVHAARAYNCTLQSRTPDQVTVELGFIGP-LTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLIAMTSEAMVKKNIQMLTQKHLD--DYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLLEHSDKLFNLNEIDSLGKPNAFSSGQQD--------------KSGLH--FGLVIDGGTLEIAM-HESLQSKFLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYIGSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWIVMGASIAAYFAFSL----AFGAVCINCNPPANPYWIVQNHVRDPAFYLVCLLSIFIALLPR 1218          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRY--SNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNN---RPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDH----RIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEEN----------------------------------DLRLCC--------------DSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFF-----------------DYGVXXXXXXXXXXXXXDTDPIPKDLIKAV--FEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLIL---SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVM------FPKIIA-------NSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFD-SKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            NNRI+TTKY   NFI  NLFEQF R+  +NL+F+F V LN++P V AF +   ++P++ +L +  IKDG+ED R+Y  D+ +NN   +   R +K   E C   WKD++VG  I+L   E IPAD+++ +SSDP G+C IET  +DGET LKQR V+K    +     E F     + E     I  F G   DH    +IG S Q     NL+LR  I+RNT  V GIV+YAG++TK  +NN   R+KRS LE +LN D+L  + +LI +C+   IG   +L GF +   +  I           L GF  FWT II+ Q +IPI+LY+++E+VK  QI  I ND   Y E  D  I+ +A NI EDLGQ++ +F DKTGTLT+N+M+FR  SI G  Y  E N                                  D RL                ++E+  L  + +I+   L  AICNT +++  NQ  +K+       T + ++       Q F                  + G +   +       +   P  +   K++   + A SL S +      +   NF       ++ +   L   +ESPDE ALV         L  RT D++ +   F    + +++L  LPFDS+RK MSVI++   T ++ +  KGADS +      +P  +         +DK+ +++ Q   D   YA  GLRTL + K+++ ++EY +W ++    E ++ N E  + E    +E+ L L+GA G+ED+LQE VP+ +E  ++AGINIW+LTGDK+ETA++IAY+ RL   ++                           LF+ SK E          F LVIDG +L + +  + L+ +FL +   C  V+CCR TP+QK +VV LV+   +V  LAIGDGANDV+MIQ ADIG+G+SG+EG QA ++SDFA++ FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F+YQ   GFS +   D    ++F+L+ T +PPII+G+ DKD S E L A P++Y +G  S+ YR   FW TILD+ +QSL  F +P   Y  +++ +  FG   ++  +  +  H++IES+  +  HW +   ++   F   L    +   V ++CN   NPY ++   +     YL+  LS  I+L PR ++
Sbjct:   75 NNRIQTTKYTLLNFIPRNLFEQFHRWVAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEKKYKESC---WKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQVVKGYSMDDEFDPEKFSGR-IQCENPTSDISSFKG-FLDHPNKEKIGLSKQ-----NLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPE-SPIFSIPEPGGQHTSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANGKVLFTKYTAKYNMKYKRFAMNPNIRYFEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETS-YIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSNFGSKLSFFTRGKLASPTAELADKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAESPDEAALVHAARAYNCTLQSRTPDQVTVELGFIGP-LTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLISPYPSCVPAPRPVQKKTDKNIQMLTQKHLD--DYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLLEHSD--------------------------KLFNLSKHEKVNAKLSGLHFGLVIDGGTLEIAM-HESLQSKFLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYIGSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWIVMGASIAAYFAFSL----AFGAVCINCNPPANPYWIVQNHVRDPAFYLVCLLSIFIALLPRYVL 1236          

Query:  249 NRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLE-EVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHN---------------------------------------NPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGG---KIQSFFDYGVXXXXXXXXXXXXXDTDP-IPKDLIKAVFEKAESLQSVSSYPKSNITA--------------DNFPHRHLTNEELSPLIL--------------SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI-------IANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRE--NNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            N+I+TTKY F+ FI  NLFEQF R++N++F+    LNF+P V AF    AIIPI  IL +T IKD  ED RR+ SD+ +N    L Y++  N+F    WKD+ VGD +KL   E IPAD+L+ + SD +G+C IET ++DGET LKQR V+K         + E F+N     E  N  + KF G                 +L+LR   +RNT EV GIV+YAG++TK  +NN   R+KRS +E Q+N+++  C+GIL I+C++  +G   +   F  I  +  +           L GF  F T II+ Q +IPI+LY+++ELVK  QI  I +DL LYDE +D  +  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  +I G  +  +EN  +  C S   EL N                                       +P+I    L  AICNT +++ + +  +++  V    T    + S+G    K Q  F     L        S   +DP  P         K   +  V S  K NI++              D+   ++  +  L  +I               +ESPDE ALV       F L  RT D++ +    +   + +++L TL FDS+RK MSV+V+   T EI +  KGADSV+   +       I++  K  ++  +T+  +  YA +GLRTL + K++L+E+E+++W     + E  + N E  + E    +E+NL L+GA G+ED+LQE VP+ +   +EAGINIW+LTGDK+ETA++IAYS +L  Q +T                    E  ++ LF   +   ++E      +  LVIDG +L+VI     L+ +FL ++  C  V+CCR TP+QK  VV LV+   +V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAI++FK+LK+L+LVHGH  Y +LA M +  FYKN+    ++F+YQ+  GFS +  ID    + F+L  T +PP++FG+ DKD S E L++ P +Y +G   K Y+   FW  I+D+ +QSLV F +P   Y  T+I +  FG    +  +  +  H+ IE + W++ HW   + ++ I +++     N++CV+   CN   NPY ++   MS    Y++  ++  I+L PR
Sbjct:   61 NKIKTTKYTFFTFIPKNLFEQFHRFANVYFVAVAALNFVPVVNAFQPAIAIIPICIILAITAIKDIWEDFRRFKSDKEINYMSCLVYNRNSNDFVEKCWKDVCVGDFVKLLCNEIIPADILLLFCSDQNGICHIETANLDGETNLKQRQVVKGFCKQGMAFDPESFRNTIV-CEKPNNNLNKFKG-------------FGNESLLLRGCTVRNTEEVVGIVVYAGHETKAMLNNSGPRYKRSKIERQMNINVFFCVGILFIMCLIGALGYGIWTSKF-VIPPLFDVPEADGSYLSPALAGFYMFLTMIILLQILIPISLYVSIELVKLGQIYLIHSDLDLYDEEIDLSVQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGYEFSHQENG-KWQCFSSVSELKNIGEKDVTPDHMLLAKVREASVKFAAVSPLVSQSNIRAASSPYI-DFFLALAICNTVVVSTATEPRQRVSPVMGSVTIPPLLKSSGSSLEKFQHLFQRLKLLSFSQSSSTSPSSSDPGTPTS------SKNNKVSPVPSADKDNISSSSSGEAECQSSGKDDSSVSKNSADNCLEEMIATVSSLHIEDDFCYEAESPDEAALVHAARAYSFTLMSRTPDQVTV-RLPQGTLLTFDLLYTLGFDSVRKRMSVVVRHPITREIIVYTKGADSVIMDLLDDPSKANISDEKKLRKMQARTQRHLDWYARDGLRTLCIAKKVLSEDEFERWSNFREEAEAAIENREELLMETAQHLETNLSLLGATGIEDRLQEGVPDTIASLREAGINIWVLTGDKQETAVNIAYSCQLLDQYDTF-----------------FPEKKKRGLFKRSKAPVSHELEAVRPQVGLVIDGRTLNVIFQGG-LETKFLELSRHCRSVLCCRATPLQKSMVVKLVRDKLKVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAISRFKHLKKLLLVHGHWCYTRLANMVIYFFYKNVAYVNLLFWYQLFCGFSGTTMIDYWQMIFFNLFFTSVPPLVFGILDKDISAETLMSLPHLYKSGQQCKSYKMSTFWIAIVDAFYQSLVCFFIPYFTYQGTDIDVLSFGTPINTIALFTILMHLAIEIKTWTILHWVTIVVSI-ICYFVVSLAYNAICVL---CNEPANPYWIMEMQMSDPLFYIVCIITPVIALLPR 1206          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI-------IANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRE----------NNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLG-------IRKWTTNVSETI-KHDPHIFDYKNS 3728
            +ESPDE ALV       F L  RT D++ +    +   + +++L TL FDS+RK MSV+V+   T EI +  KGADSV+   +       I++  K  ++  +T+  +  YA +GLRTL + K++L+E+E+++W     + E  + N E  + E    +E+NL L+GA G+ED+LQE VP+ +   +EAGINIW+LTGDK+ETA++IAYS +L  Q +TV  I+ ES+    +++    ED++K   + K+           ++E      +  LVIDG +L+VI     L+ +FL ++  C  V+CCR TP+QK  VV LV+   +V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAI++FK+LK+L+LVHGH  Y +LA M +  FYKN+    ++F+YQ+  GFS +  ID    + F+L  T +PP++FG+ DKD S E L++ P +Y +G   K Y+   FW  I+D+ +QSLV F +P   Y  T+I +  FG    +  +  +  H+ IE + W++ HW   + ++ I +++     N++CV+   CN   NPY ++   MS    Y++  ++  I+L PR  I+        +    A ++++KLG       I++W   + E++ +  P+ FD+ +S
Sbjct:  693 AESPDEAALVHAARAYSFTLMSRTPDQVTV-RLPQGTLLTFDLLYTLGFDSVRKRMSVVVRHPITREIIVYTKGADSVIMDLLDDPSKANISDEKKLRKMQARTQRHLDWYARDGLRTLCIAKKVLSEDEFERWSNFREEAEAAIENREELLMETAQHLETNLSLLGATGIEDRLQEGVPDTIASLREAGINIWVLTGDKQETAVNIAYSCQLLDQYDTVFTINTESKETCESILDCTLEDVKKFFPEKKKRGLFKRSKAPVSHELEAVRPQVGLVIDGRTLNVIFQGG-LETKFLELSRHCRSVLCCRATPLQKSMVVKLVRDKLKVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAISRFKHLKKLLLVHGHWCYTRLANMVIYFFYKNVAYVNLLFWYQLFCGFSGTTMIDYWQMIFFNLFFTSVPPLVFGILDKDISAETLMSLPHLYKSGQQCKSYKMSTFWIAIVDAFYQSLVCFFIPYFTYQGTDIDVLSFGTPINTIALFTILMHLAIEIKTWTILHWVTIVVSI-ICYFVVSLAYNAICVL---CNEPANPYWIMEMQMSDPLFYIVCIITPVIALLPRYFIRALRGTCVANPLILA-QKLDKLGKEERDLKIQQWKEKIRESMPRAAPNEFDFNSS 1340          

Query:  234 SKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLE-EVFKNYYFEVEASNKQIYKFNGKI-FDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENE 1466
            S+   N+I+TTKY F+ FI  NLFEQF R++N++F+    LNF+P V AF    AIIPI  IL +T IKD  ED RR+ SD+ +N    L Y++  N+F    WKD+ VGD +KL   E IPAD+L+ + SD +G+C IET ++DGET LKQR V+K         + E F+N     E  N  + KF G +  D+  G+     N  +L+LR   +RNT EV GIV+YAG++TK  +NN   R+KRS +E Q+N+++  C+GIL I+C++  +G   +   F  I  +  +           L GF  F T II+ Q +IPI+LY+++ELVK  QI  I +DL LYDE +D  +  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  +I G  +  +EN  RL   +E E
Sbjct:   44 SQYQTNKIKTTKYTFFTFIPKNLFEQFHRFANVYFVAVAALNFVPVVNAFQPAIAIIPICIILAITAIKDIWEDFRRFKSDKEINYMSCLVYNRNSNDFVEKCWKDVCVGDFVKLLCNEIIPADILLLFCSDQNGICHIETANLDGETNLKQRQVVKGFCKQGMAFDPESFRNTIV-CEKPNNNLNKFKGYMQLDN--GQRTGFGN-ESLLLRGCTVRNTEEVVGIVVYAGHETKAMLNNSGPRYKRSKIERQMNINVFFCVGILFIMCLIGALGYGIWTSKF-VIPPLFDVPEADGSYLSPALAGFYMFLTMIILLQILIPISLYVSIELVKLGQIYLIHSDLDLYDEEIDLSVQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGYEFSHQENAKRLEMYNEEE 451          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF-----PKIIANSD---KDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHK---------------EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRK 3665
            +ESPDE ALV       F L  RT +++ +    +   + +++L TL FDS+RK MSV+V+   T EI +  KGADSV+      P   +N D   K   I  +T+  +  YA +GLRTL + K++++E ++++W     + E +L N E  + E    +E++L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK+ETA++IAYS +L  Q +TV  I+ E++    ++++   EDI++  F   ++   K C H+               E  LVIDG +L+ I    +L+ +FL +  +C  V+CCR TP+QK  +V LV+    V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAI +F +LK+L+LVHGH  Y +LARM +  FYKN+    ++F+YQ   GFS S  ID    + F+L  T LPPIIFGV DKD S E LLA P++Y +G NS+ Y    FW ++ D+ +QSL+ F +P L Y  ++I +  FG    +  +  +  H  +E + W+V H  + +G+  + F + L I N+ CV    CN+  NPY V+   +S    YLI  L+  ++L PR  +         S+  +A ++I+KL I K
Sbjct:  689 AESPDEAALVHAARAYSFTLVSRTPEQVTV-RLPQGICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKR--FHEPQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQG-KLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSL-IYNATCVT---CNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKA-QKIDKLPIDK 1311          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQ--NVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL----CCDSENEE 1469
             N+++T+KY   +FI  NLFEQ  R++NL+F+  VILNFIP V AF  G +++P+  IL VT IKD  ED RRY SD+ +NNR  L Y +    + + +W+D+ VGD +++   E +PAD+L+ +SSDPSG+C +ET ++DGET LKQR V+K         +    +     E  N  + KF G  +     ++       +L+LR   +RNT    GIVIYAG++TK  +NN   R+KRS +E ++N D+  C+G+L ++C++  +G S +   F +    +V     NF     + L GF  F T II+ Q +IPI+LY+++ELVK  Q+  + NDL LYDE  D  I  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  +I G  Y  +EN  RL      DS+ EE
Sbjct:   40 GNQVKTSKYTVLSFIPKNLFEQLHRFANLYFVGIVILNFIPVVNAFQPGVSMVPVCAILTVTAIKDAWEDFRRYKSDKVINNRESLVYSRKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHFHSTIVCEKPNNHLSKFKG--YMEHPDQTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNF---LSLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQENAKRLEMPKELDSDGEE 448          

Query: 1809 LTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF-----PKIIANSD---KDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHK---------------EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRK 3665
            L+ +E      +ESPDE ALV       F L  RT +++ +    +   + +++L TL FDS+RK MSV+V+   T EI +  KGADSV+      P   +N D   K   I  +T+  +  YA +GLRTL + K++++E ++++W     + E +L N E  + E    +E++L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK+ETA++IAYS +L  Q +TV  I+ E++    ++++   EDI++  F   ++   K C H+               E  LVIDG +L+ I    +L+ +FL +  +C  V+CCR TP+QK  +V LV+    V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAI +F +LK+L+LVHGH  Y +LARM +  FYKN+    ++F+YQ   GFS S  ID    + F+L  T LPPIIFGV DKD S E LLA P++Y +G NS+ Y    FW ++ D+ +QSL+ F +P L Y  ++I +  FG    +  +  +  H  +E + W+V H  + +G+  + F + L I N+ CV    CN+  NPY V+   +S    YLI  L+  ++L PR  +         S+  +A ++I+KL I K
Sbjct:  706 LSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTV-RLPQGICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKR--FHEPQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQG-KLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSL-IYNATCVT---CNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKA-QKIDKLPIDK 1339          

Query:  183 ENVNIYPSNFYIPLTDESKKV-----NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQ--NVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL----CCDSENEE 1469
            E   +YP+N       + KKV      N I TTKY    F+  NLFEQF R++NL+F+F VILN++P +  F++   I P+  +L++ ++KDG+ED +RY  DR +N+  +  Y++    + + +W+D+ VGD +++   E +PAD+L+ +SSDPSG+C +ET ++DGET LKQR V+K         +    +     E  N  + KF G  +     ++       +L+LR   +RNT    GIVIYAG++TK  +NN   R+KRS +E ++N D+  C+G+L ++C++  +G S +   F +    +V     NF     + L GF  F T II+ Q +IPI+LY+++ELVK  Q+  + NDL LYDE  D  I  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  +I G  Y  +EN  RL      DS+ EE
Sbjct:   44 EQRVVYPNNSMC--HQDWKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHFHSTIVCEKPNNHLSKFKG--YMEHPDQTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNF---LSLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQENAKRLEMPKELDSDGEE 476          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF------EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEK--------------TCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
            +ESPDE ALV        AL  R  D++ +      + + +E+L TL FDSIRK MSV+++   T EI++  KGADSV+   ++  S  D       +I ++T+  +  YA  GLRTL + KR+L++ EY  W ++  + E ++ + E  + +    +E+NL L+GA G+ED+LQE VPE +   ++AG+ IW+LTGDK+ETAI+IAY+ +L    E V  ++ +S+     ++ Q    ++     S  +N+E               T       LVIDG SL+  L    L+++FL +A  C  V+CCR TP+QK  VV LV+   +  TLAIGDGANDV+MIQ AD+G+G+SG+EG QA +ASDFA+ +F+YL+RL++VHGH  Y +LA M L  FYKN +   ++F++Q   GFS S  IDQ   + F+L+ + LP ++ GV DKD   ++LL  PQ+Y +G N + YRPR FW  ++D+ +QSLV F +P L Y+++++ +  +G    +  +     H+ IE++ W+  +W  C G     F+    I N+ C         NPY  +   +     YL   ++   +L PRL  K  
Sbjct:  710 AESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPRSTLQNSESNLSVGFSFNPVSTSTDASPSPSLVIDGRSLAYAL-EKSLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLAC-GFSTFLFFSVALIYNTSCATCYP--PSNPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKAL 1309          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLC----CDSENEEL 1472
             +NR++TTKY   +F+  NLFEQF R +N++F+F  +LNF+P V AF  G A+ P+LFIL VT IKD  ED  R+ SD  +N+   L + +   ++    WK+I VGD ++L   E IPAD+L+  SSDP G+C IET ++DGET LK+R V++      +    +      E E  N  + +F G I  H  G+    L+  NL+LR   +RNT  V GIVIYAG++TK  +NN   R+KRS LE Q+N D+L C+ +L+ + + + +G   ++R + + + +  +  +              F+T IIV Q +IPI+LY+++E+VK  Q+  I  D+ LYDE  D ++  +A NITEDLGQIK +F DKTGTLT+N+M+FR  ++ G  Y  + N  RL      DSE EE+
Sbjct:   64 ADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGYIM-HSNGEKA-GLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEV 475          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI-IANSD-----KDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSL-----FDSKRENNEKTCKHK---EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIK 3590
            +ESPDE ALV         L  RT +++++ +      + + +L  LPFDS+RK MSV+V+   + ++ +  KGADSV+   + +A SD     +   I  +T+  +  YA  GLRTL + K+++++ EY +W       E ++ N E  + E    +E+ L L+GA G+ED+LQE VPE +E   +AGI IW+LTGDK+ETA++IAY+ +L   ++ +  ++ +S+     +MS I E+++K         S R+N  +    +      LVI G +L   L  + L+ +FL +  +C  V+CCR TP+QK EVV LV+ +  V TLAIGDGANDV+MIQ ADIGIGVSG+EG QA +ASDFAI++F++L +L+LVHGH  Y +L+ M L  FYKN+    ++F+YQ   GFS +   D    + F+L+ T +PPII+GV +KD S E LL  P++Y +G  S+ Y P  FW T+LD+ +QSLV F VP   Y  ++I +  FG    +  +  +  H++IES+  +  H  + +G++ + ++       +LCV    CN   NPY ++   M     YL+  L+T ++L PR L +
Sbjct:  777 AESPDEAALVYAARAYRCTLQSRTPEQVMV-DFAALGSLTF*LLHILPFDSVRKRMSVVVRHPLSKQVVVYTKGADSVIMELLSVAASDGTNPEQQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGMLMSAILEELQKRAQVSPELASSRKNFPQPSDAQGQGRAGLVITGKTLEFAL-QESLQRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHLHVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFTFGNPLNTAALFIILLHLVIESKSLTWIHMLVTVGSI-LSYFFFALAFGALCVT---CNPPSNPYGIMRKHMLDPVFYLVCVLTTFVALLPRFLYR 1368          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFIT---SNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRL 1445
            VNNRIRTTKY   NF+  NLFEQF R +NL+F+F V+LN++P V AF +   ++P++ +L +  IKDG+ED R+Y  D+ +NN     Y +   ++  C WK+++VGD I+LS  E IPAD+++ +S+DP G+C IET  +DGE+ LKQR V++      + ++    +   E E+ N  + +F G  F     K    L+  NL+LR   +RNT  V GIV+YAG++TK  +NN   R+KRS LE + N D+L C+ +LI++C+   +G   +L   ++ +N++F      +  VI  V L GF  FWT II+ Q +IPI+LY+++E+VK  QI  I +D+  Y+E MD  I  +A NITEDLGQI+ +F DKTGTLT+N+M+FR  S+ G +Y  EEN  RL
Sbjct:  125 VNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEKFSSRIECESPNNDLSRFRG--FLEHANKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWL---SRYENMLFFNIPEPDGRVISPV-LTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRL 522          

Query:  219 PLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCV-CKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFK-NYYFEVEASNKQIYKFNGKIFDHRIGKSV-QHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTG-----IIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIY--LTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGT-LGIGFYL 3434
            P   E K   N I+  KY  + FI   L+EQFK + NL+F+      F+P +      T   P+ F+L VT+ ++ +++ RR+  D+ +N++    Y K+     V  K  DI VGD+I +   +RIP+D++   +S+ +G CFI T  +DGET  K + V  S       L ++F  + Y   +     I+ F G          + + L+  N +   TI+  +  V G+VIY G +T+  MN    + K  LL+ +L                             N++   +F+      +  V LQGF   W       +++F  IIPI+L + L++ KA     I     + DE++   + V+   I E+LG++  +  DKTGTLT NEM+F+   +   +Y T+  D          E+ +  H+L   L              Q   +    +  S  L    S+  K++      +   ++ I               +  V+E    +   + + +++    +F   + T +  SP       DE ALVR     G  L  R    + +      + + Y IL+  PF S  K M +IV+D +T EI+   KGAD  M   +  N   + E  N         A  GLRTLV+ KR L E +Y+ +E   S+ + ++ +   ++  + + +E  ++L+   G+ED+LQ  V   LE  + AGI IW+LTGDK ETA  IA S+ L S+ + +             V S+    +E + F  K +     C      LVI G SL V L   E   E + +A  C  VVCCRC+P QK  +V L++++   RT AIGDG NDV+MIQ AD GIG+ GKEG QA+LA+DF+IT+F+++ RL++VHG  SY + A +   + ++ +IIS +   +  +  F++         + +  I T + P+   V D+D   E+ +  P++Y  LT   S  ++    W  +L S++Q  ++     L +   E        IS + +++     + +  R W   HW + +   L +G Y+
Sbjct:  122 PEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVVSCSQFVPALKIGYLYTYWAPLGFVLAVTIAREAIDEFRRFQRDKEMNSQ---LYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLK-VAVSCTQRLPALGDLFSISAYVYAQKPQLDIHSFEGTFTREDSDPPIHESLSIENTLWASTIV-ASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLEL-----------------------------NQLTKALFLALVVLSVVMVTLQGFAGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAAYGWMI-----MKDENIPGTV-VRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMD----------EIQS--HVLNSYL--------------QVHSQPSGHNPSSAPLRRSQSSTPKVKKSVSSRIHEAVKAIALCHN----------VTPVYEARAGITGETEFAEAD---QDFSDENRTYQASSP-------DEVALVRWTESVGLTLISRDLASMQL-KTPSGQVLTYCILQMFPFTSESKRMGIIVRDESTAEITFYMKGADVAMSTIVQYNDWLEEECGNM--------AREGLRTLVVAKRTLTEEQYQDFESRYSQAKLSIHDRALKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIH--------VFRPVTSRGEAHLELNAFRRKHD-----C-----ALVISGDSLEVCLRYYE--HELVELACQCPAVVCCRCSPTQKAHIVTLLRQHTRKRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYT-MFPVFSLVLDQDVKPEMAILYPELYKDLTKGRSLSFKTFLIW--VLISIYQGGILMYGALLLF---EDEFVHVVAISFTALILTELLMVALTIRTW---HWLMVVAEFLSLGCYV 1080          

Query:  237 KKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRP--VLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNN-STNLEEVFKNY--YFEVEASNKQIYKFNGKI-FDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCS----------FYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC---------DSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWI--VYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXX-XXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQN-ETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTI---LDSLWQSLVIFA-------VPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIAL 3551
            +  +N + TT+Y    F+   L+EQF R +N +F+   IL+  P +  FN+ + I P++F++ +++ K+ +ED RR+  D  VN+R   V R D    +F   KWK + VGD++K+   +  PADLL+  SS   G+C++ETM++DGET LK   V + LD       ++ F+++    + E  N  +Y F G + +D +    V  L+ + ++LRD+ LRNT+ V G+V++ G+ TKV  N+ ++  KRS +E +++  +     +L++V  ++ +G +          +YLR               T   + +    +   T ++++  +IPI+LY+++ELVK  Q   I  DL +YD         +  N+ E+LGQ+  +  DKTGTLT N+M F   SI G +Y    +++ L           + + EE+ + P          +     +      + +L  V + +       STG K  SF D  +               +P   D++  +      + +V       +  D       T E  SP       DE A +      GF   +RT+  + I      + +   Y++L  L F S RK MSVIV+D   G+I L CKGADS++F ++  N     E    T   +  Y   GLRTL +  R L+E EY  W     K + ++    +  ++++ D++E  L LVGA  +EDKLQ+ VP+ ++   +AG+ IW+LTGDK ETAI+I Y+  L  Q  + +       E    +  +  RE+I   + ++ +    +   H  F L+IDG +L+  L  D++K +FL +A  C  V+CCR +P QK  V  L K+     TLAIGDGANDV MIQ ADIG+G+SG EG QA +ASDF+I +F++L+RL++VHGH  Y ++A+M    FYKN+   L +F+++  +GFS     +    L+F++I T LP I  GV+++D S E+ L  P +Y  G  +  +   D++R I    + ++ S+VIF+       V S C       M   G    +C++ A+   I +   H++     +  G++     +  +I  +L  +L    + N + +L  T++    + + +L
Sbjct:   57 RYTSNYVSTTRYNLITFLPKCLYEQFHRVANFYFLVAAILSVFP-LSPFNKWSMIAPLIFVVGLSMGKEALEDWRRFMQDVKVNSRKATVHRGD---GDFGRRKWKKLRVGDVVKVEKDQFFPADLLLLSSSYEDGICYVETMNLDGETNLK---VKRCLDVTLPLERDDTFQSFSGTIKCEDPNPNLYTFVGNLEYDGQ----VYPLDPSQILLRDSKLRNTSYVYGVVVFTGHDTKVMQNSTKSPSKRSRIEKRMDYIIYTLFALLVLVSFISSLGFAVMTKMHMGDWWYLRPDKP--------ERLTNPRNPFHAWVVHLITAVLLYGYLIPISLYVSIELVKVLQATFINQDLQMYDSESGTPAQARTSNLNEELGQVDTILSDKTGTLTCNQMDFLKCSIAGTSYGVRASEVELAAAKQMAIDLDEEQGEEVTHLPRT-----RGRMHGYAKMPSKTSSDIELETVITATDEGDQTQSTGIKGFSFEDQRLMGGNWL--------NEPNSDDILMFL-----RILAVCHTAIPEVDEDT---GKCTYEAESP-------DEVAFLVAAGEFGFEFTKRTQSSVFISERHSGQPVEREYKVLNVLDFTSKRKRMSVIVRDE-KGQILLLCKGADSIIFERLSKNGKNYLE---ATSKHLNGYGEAGLRTLALSYRKLDETEYSIWNSEFHKAKTSVGADRDEMLEKVSDMMEKELILVGATAVEDKLQKGVPQCIDKLAQAGLKIWVLTGDKMETAINIGYACSLLRQGMKQIYIALRNEEGSSQDPEAAARENILMQIINASQMIKLEKDPHAAFALIIDGKTLTYAL-EDDIKYQFLALAVDCASVICCRVSPKQKALVTRLAKEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNITFGLTLFYFEAFTGFSGQAIYNDSYLLLFNVILTSLPVIALGVFEQDVSSEVCLQFPALYQQGPKNLFF---DWYRIIGWMANGVYASVVIFSLNIGIFHVQSFCSGGQTADMDAMGTAMFTCIIWAVNVQIALTMSHFTWIQHVLIWGSI-----VTWYIFLALFGMLPPKVSGNIFHMLSETLAPAPIFWLTSL 1140          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNN-STNLEEVFKNY--YFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCS----------FYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENE-ELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXD--TDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIV----YEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXX-XXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQN-ETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTI---LDSLWQSLVIFA-------VPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTY-----LIIALSTAISLF 3572
            +N + TT+Y    F+   L+EQF R +N +F+   IL+  P +  FN+ + I P++F++ +++ K+ +ED RR+  D  VN+R      K   +F    WK I VGD++++   E  PADLL+  SS   G+C++ETM++DGET LK   V + LD   +   +E F+N+    + E  N  +Y F G +        V  L+   ++LRD+ LRNT  V G+V++ G+ TKV  N+ ++  KRS +E +++  +     +L+ V  ++ +G +          +YLR  +K ++   +T+    +Y       +   T ++++  +IPI+LY+++E+VK  Q   I  DL LYD         +  N+ E+LGQ+  +  DKTGTLT N+M F   SI G +Y    +++ L    +   +L              + N ++     QR  KL    S    L  V +   +     + GV         +  E+   +P   D++  +F +   + +V       +  D       T E  SP       DE A +      GF   +RT+  + I   F          Y+IL  L F S RK MS IV+D   G+I L CKGADS++F ++   S    E +  T   +  Y   GLRTL +G R L+E EY  W     K + ++    +  ++++ D++E  L LVGA  +EDKLQ+ VP+ ++   +AG+ IW+LTGDK ETAI+I Y+  L  Q  + +       E    N  +  +E I   + ++ +    +   H  F L+IDG +L+  L  D++K +FL +A  C  V+CCR +P QK  V  L K+     TLAIGDGANDV MIQ ADIG+G+SG EG QA +ASDF+I +F++L+RL++VHGH  Y ++A+M    FYKN+   L +F+++  +GFS     +    L+F+++ T LP I  GV+++D   ++ L  P +Y  G  +  +   D++R +    + ++ S+VIF        V S         M   G    +C++ A+   I +   H++     +  G++G  +Y+ L +   L V L    + N + +L   ++    +     L+IA +T   LF
Sbjct:   61 SNYVSTTRYNLLTFLPKCLYEQFHRVANFYFLVAAILSVFP-LSPFNKWSMIAPLVFVVGLSMGKEALEDWRRFMQDVEVNSRKA-SVHKGSGDFGRRTWKRIRVGDIVRVEKDEFFPADLLLLSSSYEDGICYVETMNLDGETNLK---VKRCLDATLALEKDESFQNFSGTIKCEDPNPNLYTFVGNL---ECDGQVYPLDPNQILLRDSKLRNTAYVYGVVVFTGHDTKVMQNSTKSPSKRSRIEKRMDYIIYTLFALLLTVSFISSLGFAVMTKLLMAEWWYLRP-DKPES---LTNPTNPLY----AWVVHLITALLLYGYLIPISLYVSIEVVKVLQAHFINQDLQLYDSESGTPAQARTSNLNEELGQVDTILSDKTGTLTCNQMDFLKCSIAGTSYGVRASEVELAAAKQMAMDLEEKGE--------EVANLSMNKGRTQRYAKLASKTSSDFELETVVTASDEKDQKQNTGVKGFSFEDNRLMNENWLNEPNSDDIL--MFFR---ILAVCHTAIPEVDEDT---GMCTYEAESP-------DEVAFLVASREFGFEFTKRTQSSVFIAERFSSSGQPVDREYKILNLLDFTSKRKRMSAIVRDEE-GQILLLCKGADSIIFERL---SKSGKEYLGATSKHLNVYGEAGLRTLALGYRKLDETEYAAWNSEFHKAKTSVGADRDEMLEKVSDMMEKELILVGATAVEDKLQKGVPQCIDNLAQAGLKIWVLTGDKMETAINIGYACSLLRQGMKQISISLTNVEESSQNSEAAAKESILMQITNASQMIKIEKDPHAAFALIIDGKTLTYAL-KDDVKYQFLALAVDCASVICCRVSPKQKALVTRLAKEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNITFGLTLFYFECFTGFSGQSIYNDSYLLLFNVVLTSLPVISLGVFEQDVPSDVCLQFPALYQQGPKNLFF---DWYRILGWMGNGVYASIVIFTLNLGIFHVQSFRSDGQTADMNAMGTAMFTCIIWAVNVQIALTMSHFTWIQHVMIWGSIG-AWYVFLALYGMLPVKL----SGNIFHMLVEILAPAPIFWLTSLLVIAATTLPYLF 1154          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPV-LRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYF----EVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNK---IQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITN-DLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKW-----IVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFS--------QNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEK--TCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTIL----DSLWQSLVIFAVPSLCYWNTEISMGE-FGIISVS-----CVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKG 3593
             N I TTKY  + F+   LFEQF+R +N++F+    L+  P +   +  T + P+  +L+V+LIK+  ED +R+ +D ++NN  V +  D+   ++    W+ + VGD++K+      PAD+L   S++  G+C++ET ++DGET LK R   K+L+     L    K Y F    + E  N  +Y F G +    + K    L+   L+LR   LRNT  + G V++ G++TKV MN   A  KRS LE +L+  ++    +L+ +C++  IGCS      +K   + N  +   N  +I      GF  F+T + +F SIIPI+LY+++E++K  Q     N DL +Y    +     +  N+ E+LGQ++ +F DKTGTLT N M F   SI G +Y         C  +E E+     H L++                Q E++               STG   +  F++      +P L       +P P DL K +F       +V   P+ + + +   ++            + SPDE ALV      GF  ++RT   + +  +   K      + YEIL  L F+S RK  SV+ +    G + L CKGAD+V+F ++ AN   D   +  T+  +  + S+GLRTL +  + LN   Y  W E   + +  L + E ++ E+ +LIE +L L+G+  +EDKLQE VP  +E    AGI IW+LTGDK ETAI+IAY+  L +         +ET      E   + + +   I+E++++ L  S  E      T    +  LVIDG  L   L    L+   L ++  C  VVCCR +P+QK +V  LV+K  +  TL+IGDGANDV+MIQ A +GIG+SG EG QA +ASDFAI +F++L  L+LVHG  SY ++ ++ +  FYKN+  +L  F++   +GFS  +  D   Q +F+++ T LP I+ G+++KD S  +    P++Y  GI +  ++    WR +      +++QSLV +   +   +    S G+ FG+  VS     C+VIA+   I++ S   + +H+ I +G   + + +  F+    C ++   +  +N Y V++  MS    Y  + L   +SL    + +G
Sbjct:   53 GNSISTTKYNVFTFLPKGLFEQFRRIANIYFLGISCLSMTP-ISPVSPITNVAPLSMVLLVSLIKEAFEDWKRFQNDMSINNSTVEILQDQ---QWVSIPWRKLQVGDIVKIKKDGFFPADILFMSSTNSDGICYVETANLDGETNLKIR---KALERTWDYLVPE-KAYEFKGEIQCEQPNNSLYTFTGNLV---VQKQTLPLSPDQLLLRGCSLRNTEYIVGAVVFTGHETKVMMNAMNAPSKRSTLEKKLDKLIITIFCVLVTMCLIGAIGCSIVTDREDKYLGLHNSDWEYRNGLMI------GFFTFFTLVTLFSSIIPISLYVSIEMIKFIQSTQFINRDLNMYHAETNTPASARTSNLNEELGQVEYIFSDKTGTLTRNLMEFFKCSIGGVSYG--------CGVTEIEKGIAQRHGLKV----------------QEEQR---------------STGAIREKGFNFD-----DPRLMRGAWRNEPNP-DLCKELFRCLAICHTV--LPEGDESPEKIVYQ------------AASPDEAALVTAAKNFGFFFYRRTPTMVYVRESHVEKMGKIQDVAYEILNVLEFNSTRKRQSVVCR-FPDGRLVLYCKGADNVIFERL-ANGMDDVRKV--TREHLEHFGSSGLRTLCLAYKDLNPETYDSWNEKFIQAKSALRDREKKLDEVAELIEKDLILIGSTAIEDKLQEGVPTCIETLSRAGIKIWVLTGDKMETAINIAYACNLINNEMKQFVISSETDAIREAEERGDQVEIARVIKEEVKRELKKSLEEAQHSLHTVAGPKLSLVIDGKCLMYAL-DPSLRVMLLSLSLNCTSVVCCRVSPLQKAQVTSLVRKGAQKITLSIGDGANDVSMIQAAHVGIGISGMEGMQAVMASDFAIAQFRFLTDLLLVHGRWSYLRICKVVMYFFYKNLTFTLTQFWFTFRTGFSGQRFYDDWFQSLFNVVFTALPVIVLGLFEKDVSASLSKRYPELYREGIRNSFFK----WRVVAVWATSAVYQSLVCYLFVTTSSFGAVNSSGKVFGLWDVSTMVFTCLVIAVNVRILLMSNSITRWHY-ITVGGSILAWLVFAFV---YCGIMTPHDRNENVYFVIYVLMSTFYFYFTLLLVPIVSLLGDFIFQG 1114          

Query:  534 VCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKI---------FDHRIGKSVQH--LNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFP-----HRHLTNEELSPLIL-SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDI---------EKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCY-------W---NTEI--SMGEFGIISVSCVVIAMFSHIMIESRHW-SVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRG----KTYLIIALSTAISLFPRL 3581
            VC+ K + VGD++K+ + E IPADLLI  + + +G+C++ET ++DGET LK ++ + S     +       +++ E E  +  +Y  NG +          +   G+ +     + +N++L    LRN+  V G+V+Y G++T++  N      KRS +   LN  +++   +L  +C+ +G+  S Y    N    V  ++ N          G I  +T +I+FQ+++PI+LYIT+++V++ Q   I +D  +YDE +D     K++NI++DLGQI+ +F DKTGTLT N M F+  SI G  Y    N+    C  +   L+ N ++                K +  +KK++   S S S                                   P P+ +     +  + LQS  +Y ++    + F      H  +T+ +   LI  ++SPDE+ALV++    GF L      +  I    + K   + +L  +PF S RK MSVI++D   G I L CKGAD+V+FP++ +  +    II +TK  + +++S G RTL + +R +++ +Y +W+   ++    +     ++ ++ ++IE  L+L+G   +EDKLQE VPE +     AGI +W+LTGDK ETAI+I YS  L   N T+  I   S   +  V + IR  +         ++      ++++  + KH    +VIDG +L+ +L S+++   FL +   C  V+CCR +P QK  VV LVKK   V TLAIGDGANDV+MIQ AD+G+G+ G EG  A++++D+AI +F +L RL+LVHG   Y ++++M    FYKN+I + ++F+YQ  + F  +   D    ++F+L+ T LP II G +D+D    + + NP +Y  GI    +  + FW  +LD ++QSLV F V    +       W   N E    +G F I S +  VI +F  +  E  +  S+  W   IG     F++  FI + +           P    H + SR       + +  L+ A+ L PR 
Sbjct:  322 VCR-KSLLVGDIVKVLADEAIPADLLILSTENSNGVCYVETKNLDGETNLKDKYALCSTKCCKSEYRCSAASFWVECEQPHADLYSLNGVVKAPGAVQSPSESTNGRKIHEEPFSISNVLLCGCTLRNSKWVIGLVLYTGSETRIQKNRGLTPSKRSRITRDLNWTIILNFLLLFAMCLFSGVLRSIY-SAQNNSARVFELSKNSNT---APAHGIISIFTSLILFQNLVPISLYITMDIVRSIQSYFIFSDREMYDEKLDCPCSPKSWNISDDLGQIEYIFSDKTGTLTQNIMSFKKCSINGIRYGKSHNEDT--CIKKRRNLNYNENL--------------SCKVDLDKKKMLETLSLSDS-----------------------------------PNPESITFISSKFVDHLQSNENYIQTEACFEFFKALALCHSVVTDVQDETLIYNAQSPDEEALVKVARDFGFTLLNTKNRRYTIRIRGENK--NFRVLDIIPFTSTRKRMSVIIRDE-DGIIHLICKGADTVIFPRLSSGQNN---IIEKTKKHLASFSSEGFRTLCIARRTIDKQDYLEWKVNFNEANSAIHERNEKVSKVSEMIEQELELLGGTAIEDKLQENVPETIALLAIAGIKLWVLTGDKVETAINIGYSCNLLDPNMTIFRIDANSFGALEEVEAFIRNTLCFNFGYMGTDEEFRFLLKDHSPPSPKH---AIVIDGDALNFVL-SEQVSFLFLMLCKQCKTVLCCRVSPSQKAAVVALVKKSLNVVTLAIGDGANDVSMIQEADVGVGIKGVEGQAASMSADYAIGQFSFLGRLLLVHGRWDYKRMSQMISFFFYKNVIWTFILFWYQFYNEFDGNYIFDYTYVMLFNLLFTSLPVIIAGCFDQDVDASVSMKNPSLYQRGILGLEWNGKRFWSYMLDGIYQSLVCFGVALFVFKFGDFVSWTGRNIECIEDIGLF-ISSPTIFVINIFILMNQERLNLISLITWMFSIGV----FWIWTFIYSEV----------GPSYAFHKSASRTCQTFGFWCVTVLTIALCLLPRF 1299          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNN 491
            +N+IRTTKY   +FI  NL+ QFK  +N FF+F  +L  IP     + G + IP+  IL+ T IKDG+ED RR   D+  NN
Sbjct:  130 SNKIRTTKYTPVSFIPKNLWNQFKNIANAFFLFVTLLQCIPLFCPEHLGLSFIPLSVILLTTAIKDGIEDYRRCVLDKKFNN 211          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMF-----PKIIA--NSDKDFEIIN-QTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMS-------QIRE--DIEKSLFDSKRENNEKTCKHKEFV----LVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKL 3653
            +ESPDE ALV       F L  RT +++ +    +   + + +L TL FDS+RK MSV+V+   TGEI +  KGADSV+      P  +   N +K    I  +T+  +  YA +GLRTL + K++++E ++++W     + E +L N +  + E    +E+ L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK+ETA++IA+S RL +Q +TV  I+ E++    ++++       Q RE    ++ LF  +  +   +   +  V    LVIDG +L+ I    +L+++FL +  +C  V+CCR TP+QK  +V LV+    V TL+IGDGANDV+MIQ ADIGIG+SG+EG QA ++SDFAIT+FK+LK+L+LVHGH  Y +LARM +   YKN+    ++F+YQ   GFS+S  ID    + F+L  T LPP++FGV DKD S E LLA P++Y +G NS+ Y    FW +++D+ +QSL+ F +P L Y  ++I +  FG    +  +  +  H  +E + W++FH  + +G+  + ++L   + N+ CV+   CN+  NPY V+   +S    YL+  L+  ++L PR            S+  +A ++I+KL
Sbjct:  719 AESPDEAALVHAAHAYSFTLVSRTPEQVTV-RLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQG-KLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSF-LMYFLVSLLYNATCVI---CNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA-QKIDKL 1337          

Query:  195 IYPSN--FYIPLTDESKK-VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLE-EVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC----DSENEE 1469
            ++P+N  F+    + S++   NR  TTKY  + F+  NLFEQF R++NL+F+F VILN++P +  F++   ++P+  +L V +IKDG+ED +R+  D+ +N   +  Y++    +    WKD+ VGD I++   E +PAD+L+ +SSDP+G+C +ET  +DGET LKQR V+K         E E+F N     E  N  + KF G  +     ++     C +L+LR   +RNT    GIVIYAG++TK  +NN   R+KRS +E ++N+D+  C+GILI++C++  +G S +   F +        +N + +    L GF  F T II+ Q +IPI+LY+++ELVK  Q+  ++NDL LYDE  D  I  +A NI EDLGQI+ +F DKTGTLT+N+M+FR  +I G  Y  +EN  RL      DS+ EE
Sbjct:   48 VFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV-CEKPNNHLNKFKG--YMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSA-LGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEE 476          

Query:  192 NIYPSNFYIPLTDE-----SKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYY--------FEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGN--------------------QTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEE--NDLRLCCDSEN------EEL---------------HNNPH---ILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFD-YGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSS----YPKS-NITADNFPHR------HLTNEE---------------LSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFE--IINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFS-QNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTC-------------KHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIK 3590
             + P++   P T        ++ NNRIRTTKY   +F+  NL EQF R +NL+FIF V+LN++P + AF +  A+IP+LF+L VT +KD  ED RR+ SD+ +NN     Y++  + +    WKD+ VGD+I LS+ E +PAD+L+  SSD SG+C+I+T  +DGET LKQR V +        +E+V + ++         EVE+   +IY+F+G I  H  G+ V  +   NL+LR+ +L+NT+ + GIV+YAGN                    +TK  +NN   R+KRS LE Q+N D++ C+ ILI++CI+  IGC  +L  F  +++     S+        ++ F+ FWT +I+ Q +IP++LY+TLEL K  Q+ HI +++ LYD  MDK+I+ +A NITE+LGQI+ +F DKTGTLT+N MIFRN +I G +Y   E  N+ + C    N      E+L                 N H   I + LLL A+CNT + +K    +    ++++  T+     S   K     +   V+         +      +P        E +ES++  +S     PK  +I +  F  R      +LT+EE               L P+  +ESPDE ALV         L +RT  ++ +    K + ++++IL  LPFDS RK MSVI +   T EI L CKGADS M P+++   D   +  I+N+T+  + +YA  GLR LVM KR+L++ EY  W     ++E ++ N E +I++ Y+ IE N+ L+GA G+ED+LQE VPE L     AGI +W++TGDK ETAI+IAYS +LFS Q E +K ++   ES    +   +  DIE  L  ++ EN E+ C             K +   LV+DG +L+ IL     L + FL +   CN V+CCR TP+QK  +V +VK+  ++RTLAIGDGANDV+MIQTAD+GIG+SG+EG QA +A+DFA+++FKYL+R +LVHGH SYD+L++M L  FYKN     ++F+YQ   GFS S  IDQ+  ++++L+ T LPPI  GV+D+D    +L  NP +Y  G   + YR   FW T+ DSL+QS+V+F +  + Y  T++ + EFG  + +  +  M  H+ IE+R W++ H A    ++G  F+L     N+ CV   +C    + Y  +  +M R + +L+  L+  +++ PRLL +
Sbjct:  208 TVVPNHIVPPKTPRKVHPNGRRPNNRIRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWVPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKKINNSTCRIYNREHSRYRKVLWKDVRVGDLIHLSNNEVVPADILLLRSSDSSGLCYIDTGHLDGETNLKQRQVARGF------IEKVTQRWFEPSKFRSKIEVESPTTKIYRFHGSIV-HDSGQRVP-VGTDNLLLRECLLKNTDFIEGIVVYAGNVVVRLLQPSQLIVEFIILGHETKALLNNGGPRYKRSSLEKQMNQDVVWCVLILILMCILGAIGCKLWLLAFPDLKSPFREESD-------QIEAFLAFWTYVIILQIMIPLSLYVTLELCKILQVYHIHHNVDLYDSVMDKRIECRALNITEELGQIQYIFSDKTGTLTENRMIFRNCAIAGIDYNHPELENEAQNCNKQGNLSVKVNEQLVTDLNQGVTAEHVFSSRNVHSARIQEFLLLLAVCNTVVCSKHPHHD----NMNASETASPKSRSICDKYSRLEESRSVTPSPPLNAFGADSKRSYVPTLSPIESVENSESMEGQASSRSLRPKLLSIPSIGFLSRKSNSTVNLTDEEKVKLGHAASPLSPSDLKPIYEAESPDELALVDAAYIYKCRLLRRTPTEVTVDVPMKGR-MMFKILNILPFDSTRKRMSVIFRHPTTSEIILYCKGADSSMIPRLVPAEDDSEQTFILNKTQVHLGSYAREGLRVLVMAKRVLSQQEYNDWTTKHQEIELSVDNVEKKIRDSYNYIECNMTLLGATGIEDRLQEGVPETLTALIAAGIVVWVVTGDKPETAINIAYSAKLFSPQMELLKIMARSKESAESTIRCYL-ADIE--LQSNQAENAEEHCSAGCSSRIGPQMPKPQGRALVVDGKTLTYILDRRSNLTKPFLKLTTACNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSRFKYLERFLLVHGHWSYDRLSKMVLYFFYKNATFVFLIFWYQFYCGFSGSVMIDQMYLMLYNLLFTSLPPIAIGVYDQDAPYRLLRDNPYLYKRGRLGRAYRTYSFWMTMADSLYQSVVVFWLCKMAYEGTDVDIFEFGTATTTACMCVMLLHVSIETRSWTIIHAASIFCSIG-AFFLYSLTYNTFCV---NCFGLPSTYWTIQISMHRPQYWLVTLLACVVAVLPRLLFR 1417          

Query:  177 HDENVNIYPSNFYIPLTDESK------KVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYK-------------------------TEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTG--------------GKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVF-----------------EKAESLQSVSSY-PKSNITADNFPHR-------HLTNEELS------------PLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI--IANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQN-ETVKXXXXXXXXXXXNV---MSQIREDIEKSLFDSKRENNEKTC----------KHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLL 3584
             +E   I   N  +P     K      + NN++RTTKY   +F+  NL EQF R +NL+FIF V+LN+ P + AF +  A+IP+LF+L VT +KD  ED RR+ SD+ VNN     Y      +    WK++ VGD+I LS+ E +PAD+L+  +S P+G+C+I+T  +DGET LKQR V ++        E      + EV+A   +IY+F+G +      + V  +   NL+LR+ +L+NT+ V GIV+YAG++TK  +NN   R+KRS LE Q+N D+  C+ +L+I+C++  +GC  +L+ +N+I+    + ++         + F+ FWT II+ Q +IP++LY+TLE+ K  Q+ HI +++ LYD   DK+++ +A NITE+LGQ++ +F DKTGTLT+N MIFR  +I G +Y                           E+ D +L   S   +  +   I + LLL A+CNT +   S+     L++      +++NV +T               G++ S  D    L     +  S         D ++A                   E A+S    SS+ PK NI++  F          +LT+E+ +            P+  +ESPDE ALV         L +R    +I+ +      + YEIL+ LPFDS RK MS+I++   T EI++ CKGADS + P +  I +  +  +IIN+T+  ++ YAS GLR L+M KRIL+ +EY  W     + +    N +++++E Y ++E  L L+GA G+ED+LQE VPE L     +GI +W+LTGDK+ETAI+IA+S +LF+ + E +K ++   ++    +   +++I E  E +  D + + +  T           K     LV+DG SL+ IL     L + FL +  FCN V+CCR TP+QK  +V +VK+  ++RTLAIGDGANDV+MIQTAD+GIG+SG+EG QA +A+DFA++KFKYL+R +LVHGH SYD+LARM L  FYKN     ++F+YQ+  GFS +  IDQ+  ++++L+ T LPP+  GV+D+D  +++L   P +Y  G   K+YR   FW T+ D+L+QSL IF +    Y +T I + EFG    +  +  M  H+ IE + W++ H A  + ++G  FY+   + NSLCV   +C    + Y V+ + +     +L   LS  I+L PRL+
Sbjct:  168 QEERYRIVVPNHTVPPKTPRKEHPNGNRPNNKVRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKRVNNSTCRIYQSEAARYKKVLWKELRVGDLIHLSNNEVVPADILLLRTSAPNGVCYIDTGHLDGETNLKQREVPRTFLKKQEIFEPSKFRSHIEVDAPTTKIYRFHGAMLHPSGAREV--VGTENLLLRECLLKNTDYVEGIVVYAGHETKAMLNNGGPRYKRSALERQMNQDVFWCVLVLVILCVIGAVGCKLWLQAYNQIKEPFKLEASSEST-----EAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDTETDKRVECRALNITEELGQVQYIFSDKTGTLTENRMIFRRCTIAGVDYNHHNLENEGRGAKASAALSVIINPKLKEDLDSQLSEQSTIAQQRHAARIQEFLLLLAVCNTVVC--SHHPHCDLMNASGVIEAVSNVFATSGSARLNSIDCTDRDGQMHSTNDKYERLKESRSVTPSPPLNSHTHNDSLRATHVPSLTPINSVESSPNAEEIAQSCAIKSSFRPKLNISSLPFLGNKRNGNSCNLTDEQKAKLNCSTTLFDSKPIFEAESPDELALVDAAYSYNCRLLKRNPGSVIV-DVPGEGILEYEILQVLPFDSYRKRMSIILRHPHTNEITVYCKGADSSILPNLAPIEDDSEQKQIINRTQQQLHTYASKGLRVLLMAKRILSFSEYTDWLAMHQEYQLLHENRDSKLRESYSMLERKLSLLGATGIEDRLQEGVPETLVSLVASGIVVWVLTGDKQETAINIAFSAKLFNSDMEILKIMARSKKAAEDTIKCYLTEIEECSESNGSDRRSQPSSSTSELLRRTRVNRKKYSRALVVDGKSLTYILDKRSNLTKHFLKLTTFCNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSKFKYLERFLLVHGHWSYDRLARMVLYFFYKNAAFVFLIFWYQLYCGFSGAVMIDQMYLMLYNLLFTSLPPLAIGVYDQDSPEDLLRQKPYLYRKGRLGKVYRSFSFWLTLADALYQSLAIFFICVAVYMDTAIDIWEFGTTVTTICMFVMSCHVAIEIKSWTIIHVASIVISIG-AFYVYSILYNSLCV---NCFGLPSTYWVIQHAIISPTYWLSTLLSIVIALLPRLV 1389          

Query:  177 HDENVNIYPSNFYIPLTDESK------KVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYK-------------------------TEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTG--------------GKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVF-----------------EKAESLQSVSSY-PKSNITADNFPHR-------HLTNEELS------------PLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI--IANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQN-ETVKXXXXXXXXXXXNV---MSQIREDIEKSLFDSKRENNEKTC----------KHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPR---LLIKGFLMESRDSVFYEAHRRINKLG 3656
             +E   I   N  +P     K      + NN++RTTKY   +F+  NL EQF R +NL+FIF V+LN+ P + AF +  A+IP+LF+L VT +KD  ED RR+ SD+ VNN     Y      +    WK++ VGD+I LS+ E +PAD+L+  +S P+G+C+I+T  +DGET LKQR V ++        E      + EV+A   +IY+F+G +      + V  +   NL+LR+ +L+NT+ V GIV+YAG++TK  +NN   R+KRS LE Q+N D+  C+ +L+I+C++  +GC  +L+ +N+I+    + ++         + F+ FWT II+ Q +IP++LY+TLE+ K  Q+ HI +++ LYD   DK+++ +A NITE+LGQ++ +F DKTGTLT+N MIFR  +I G +Y                           E+ D +L   S   +  +   I + LLL A+CNT +   S+     L++      +++NV +T               G++ S  D    L     +  S         D ++A                   E A+S    SS+ PK NI++  F          +LT+E+ +            P+  +ESPDE ALV         L +R    +I+ +      + YEIL+ LPFDS RK MS+I++   T EI++ CKGADS + P +  I +  +  +IIN+T+  ++ YAS GLR L+M KRIL+ +EY  W     + +    N +++++E Y ++E  L L+GA G+ED+LQE VPE L     +GI +W+LTGDK+ETAI+IA+S +LF+ + E +K ++   ++    +   +++I E  E +  D + + +  T           K     LV+DG SL+ IL     L + FL +  FCN V+CCR TP+QK  +V +VK+  ++RTLAIGDGANDV+MIQTAD+GIG+SG+EG QA +A+DFA++KFKYL+R +LVHGH SYD+LARM L  FYKN     ++F+YQ+  GFS +  IDQ+  ++++L+ T LPP+  GV+D+D  +++L   P +Y  G   K+YR   FW T+ D+L+QSL IF +    Y +T I + EFG    +  +  M  H+ IE + W++ H A  + ++G  FY+   + NSLCV   +C    + Y V+ + +     +L   LS  I+L PR   L+IK  +     +     +RR N+ G
Sbjct:  168 QEERYRIVVPNHTVPPKTPRKEHPNGNRPNNKVRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKRVNNSTCRIYQSEAARYKKVLWKELRVGDLIHLSNNEVVPADILLLRTSAPNGVCYIDTGHLDGETNLKQREVPRTFLKKQEIFEPSKFRSHIEVDAPTTKIYRFHGAMLHPSGAREV--VGTENLLLRECLLKNTDYVEGIVVYAGHETKAMLNNGGPRYKRSALERQMNQDVFWCVLVLVILCVIGAVGCKLWLQAYNQIKEPFKLEASSEST-----EAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDTETDKRVECRALNITEELGQVQYIFSDKTGTLTENRMIFRRCTIAGVDYNHHNLENEGRGAKASAALSVIINPKLKEDLDSQLSEQSTIAQQRHAARIQEFLLLLAVCNTVVC--SHHPHCDLMNASGVIEAVSNVFATSGSARLNSIDCTDRDGQMHSTNDKYERLKESRSVTPSPPLNSHTHNDSLRATHVPSLTPINSVESSPNAEEIAQSCAIKSSFRPKLNISSLPFLGNKRNGNSCNLTDEQKAKLNCSTTLFDSKPIFEAESPDELALVDAAYSYNCRLLKRNPGSVIV-DVPGEGILEYEILQVLPFDSYRKRMSIILRHPHTNEITVYCKGADSSILPNLAPIEDDSEQKQIINRTQQQLHTYASKGLRVLLMAKRILSFSEYTDWLAMHQEYQLLHENRDSKLRESYSMLERKLSLLGATGIEDRLQEGVPETLVSLVASGIVVWVLTGDKQETAINIAFSAKLFNSDMEILKIMARSKKAAEDTIKCYLTEIEECSESNGSDRRSQPSSSTSELLRRTRVNRKKYSRALVVDGKSLTYILDKRSNLTKHFLKLTTFCNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSKFKYLERFLLVHGHWSYDRLARMVLYFFYKNAAFVFLIFWYQLYCGFSGAVMIDQMYLMLYNLLFTSLPPLAIGVYDQDSPEDLLRQKPYLYRKGRLGKVYRSFSFWLTLADALYQSLAIFFICVAVYMDTAIDIWEFGTTVTTICMFVMSCHVAIEIKSWTIIHVASIVISIG-AFYVYSILYNSLCV---NCFGLPSTYWVIQHAIISPTYWLSTLLSIVIALLPRLVFLVIKNTISPDDVTRALITYRRDNRRG 1416          

Query:  195 IYPSNFYIPLTDE-----SKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTE--ENDLRLCCDSEN------EEL---------------HNNPH---ILQLLLLSAICNTTIIAKSNQRE--------KKLVHVDSCST--SLTNVTSTGGKIQSFFD--------YGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSS----YPKS-NITADNFPHR------HLTNEE---------------LSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFE--IINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFS-QNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTC-------------KHKEFVLVIDGCSLSVIL-TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDC-NTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIK 3590
            + P++   P T        ++ NNRIRTTKY   +F+  NL EQF R +NL+FIF V+LN++P + AF +  A+IP+LF+L VT +KD  ED RR+ SD+ +NN     Y++  + +    WKD+ VGD+I LS+ E +PAD+L+  SSDPSG+C+I+T  +DGET LKQR V +         E        EVE+   +IY+F+G I  H  G+ V  +   NL+LR+ +L+NT+ + GIV+YAG++TK  +NN   R+KRS LE Q+N D++ C+ ILI++CI+  IGC  +L  F  +++     S+        ++ F+ FWT +I+ Q +IP++LY+TLEL K  Q+ HI +++ LYD  MDK+I+ +A NITE+LGQI+ +F DKTGTLT+N+MIFRN +I G +Y     EN+ + C    N      E+L                 N H   I + LLL A+CNT + +K    +        + L ++ S +   S+  V +   K +S  D          V+         +      +P        E +ES++S +S     PK  +I +  F  R      +LT+EE               L P+  +ESPDE ALV         L +RT  ++ +    K + ++++IL  LPFDS RK MSVI +   T EI L CKGADS   P+++   D   +  I+N+T+  + +YA  G                  W     ++E ++ N E +I++ Y+ IE N+ L+GA G+ED+LQE VPE L     AGI +W++TGDK ETAI+IAYS +LFS Q E +K ++   ES    +   +  DIE  L  ++ EN E+ C             K +   LV+DG +L+ IL     L + FL +   CN V+CCR TP+QK  +V +VK+  ++RTLAIGDGANDV+MIQTAD+GIG+SG+EG QA +A+DFA+++FKYL+R +LVHGH SYD+L++M L  FYKN     ++F+YQ   GFS S  IDQ+  ++++L+ T LPPI  GV+D+D    +L  NP +Y  G   + YR   FW T+ DSL+QS+V+F +  + Y  T++ + EFG  + +  +  M  H+ IE+R W++ H A    ++G  F+L     N+ CV   +C    + Y  +  +M R + +L+  L+  +++ PRLL +
Sbjct:  209 VVPNHIVPPKTSRKVHPNGRRPNNRIRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWVPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKKINNSTCRIYNREHSRYRKVLWKDVRVGDLIHLSNNEVVPADILLLRSSDPSGLCYIDTGHLDGETNLKQRQVARGFIEKQRWFEPSKFRSKIEVESPTTKIYRFHGSIV-HDSGQRVP-VGTDNLLLRECLLKNTDFIEGIVVYAGHETKALLNNGGPRYKRSSLEKQMNQDVVWCVLILILMCILGAIGCKLWLLAFPDLKSPFREESD-------QIEAFLAFWTYVIILQIMIPLSLYVTLELCKILQVYHIHHNVDLYDSVMDKRIECRALNITEELGQIQYIFSDKTGTLTENKMIFRNCAIAGIDYNHPGLENEAQNCNKQGNLSVKVNEQLVRDLNQGVTAEHVFSSRNVHSARIQEFLLLLAVCNTVVCSKHPHHDNMNASGIIEALPNILSSAEEDSVKAVETASPKSRSICDKYSRLEESRSVTPSPPLNAFGADSKRSYVPTLSPIESVENSESMESQASSRSLRPKLLSIPSIGFLRRKSNSTVNLTDEEKVKLGHAASPLSPSDLKPIYEAESPDELALVDAAYIYKCRLLRRTPTEVTVDVPMKGR-MMFKILNILPFDSTRKRMSVIFRHPTTSEIILYCKGADSSTIPRLVPAEDDSEQTFILNKTQVHLGSYAREGXXXXXXXXXXXXXXXXNDWSTKHQEIELSVDNVEKKIRDSYNNIECNMTLLGATGIEDRLQEGVPETLTALIAAGIVVWVVTGDKPETAINIAYSAKLFSPQMELLKIMARSKESAESTIRCYL-ADIE--LQSNQAENAEEHCSAGCSSRIGPQMPKPQGRALVVDGKTLTYILDRRSNLTKPFLKLTTACNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSRFKYLERFLLVHGHWSYDRLSKMVLYFFYKNATFVFLIFWYQFYCGFSGSVMIDQMYLMLYNLLFTSLPPIAIGVYDQDAPYRLLRDNPYLYKRGRLGQAYRTYSFWMTMADSLYQSVVVFWLCKMAYEGTDVDIFEFGTATTTACMCVMLLHVSIETRSWTIIHAASIFCSIG-AFFLYSLTYNTFCV---NCFGLPSTYWTIQISMHRPQYWLVTLLACVVAVLPRLLFR 1416          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY--------KTEENDLR---------------------------------LCCDSENEELHNNP---HILQLLLLSAICNTTIIAKSNQRE---KKLVHVDSCSTSLTNVTSTGGKIQS--FFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF-EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSL--FDSKRENNEK------------------------------------TCKH-KEFVLVIDGCSLSVIL--TSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFG-IISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNT-DNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGF 3596
             +N +RTTKY   +F+  NLFEQF R++NL+F+  V+LN++P++ AF +  A+IP+LF+L VT IKD  ED RRY SD+ VNN     Y+K    +    WK + VGD++ LS  E IPAD+L+  SSD  G+C+IET ++DGET LKQR V++    +S     +      E +  N +IY+F+G I  H  G+ V  +   NL+LRD +L+N + V GIV+YAG +TK  +NN   R+KRS LE  +N D++ C+ IL+++C +  +GC+ +LR F   + VIFI       Y   ++GFI FWT II+ Q +IP++LY+++E++K  Q+ HI  D+ L+DE  +++++ +A NI E+LGQ++ +F DKTGTLT+N M+FR  +I G++Y        + EEND++                                 L  D   ++L  +P    + +  LL A CNT I++K   ++      +++++ S   T+       ++        +  P+     ++   TD       +        L  V+S  +  +T    P     + +L P+  +ESPDE ALV      G  L +RT D + +        I Y +L  LPFDS RK MS+I++   T +  L CKGADS + P +    D+   ++I +T+  +  Y+  GLR L M K++L + EY++W E     E ++   E  +     L+E+NL+L+GA G+ED+LQE VPE +   + AGI IW+LTGDK+ETA++IAYS RLFS +  V  ++  S+      +    E +++ L  F +  E +++                                    + +H K+  LVIDG +LS IL  ++D+L   FL +A  C+ V+CCR TP+QK  VV LVK    V TLAIGDGANDV+MIQ ADIG+G+SG+EG QA +ASDFA+ +F+YL+RL+LVHGH  YD+LAR  +  FYKN     ++F+YQ+  GF+ +  IDQ+  ++++++ T LPP+I G++D+D    +LL  P +Y  G  SK Y    FW  +LD+L+QS++IF VP   Y+++++ + EFG  I  +C  + M  H+ IE + W++ H    + +  + F   L + NS+C    D  T  NPY V+ + MS  + +L + L   IS  PR +++  
Sbjct:   83 ADNAVRTTKYTLLSFVPRNLFEQFHRFANLYFLGIVLLNWVPQINAFGKEVAMIPVLFVLGVTAIKDAFEDHRRYVSDKRVNNSTCRVYNKQSGRYVKTLWKHVRVGDIVHLSCNEVIPADILVLRSSDDQGLCYIETANLDGETNLKQRQVVRGYAQHSDTFHPLSFTSTVECDPPNCKIYRFHGFIC-HPTGEKVP-ITSDNLLLRDCVLKNADFVEGIVVYAGFETKAMLNNNGPRYKRSRLERFMNRDIVWCIVILLVLCSVGAVGCALWLRSFENRKEVIFIPYEQENRYIPAVEGFIAFWTYIIILQVMIPLSLYVSIEIIKLGQVFHIHEDIELFDERSNRRLECRALNIPEELGQVQYIFSDKTGTLTENHMVFRRCTIGGRDYNHHHPSVSEAEENDIKIRSYSCGSKPSKDDTVFTLNPQLQRELSNMEYQLRMDGSGQQLFLSPESQRVQEFFLLMATCNTVIVSKYPHKDIMNSSGLYLNNGSAHPTSPDGCRSPLKPSCLLPSALPSPVARSPAVASTPTDSRASTPTRPHKLALPFLNFVTSPSRRTMTPSPTP-----SPQLQPIYEAESPDEIALVDAASRYGCKLLRRTPDAVTLMLP-GEGLIEYRVLHLLPFDSFRKRMSIILQHPITKQKVLYCKGADSAILPLLAPTKDQVMRQVILRTQQHLNQYSKKGLRVLCMAKKVLEDEEYEEWLEQHKASELSVGEAEERLVSSARLMETNLELLGATGIEDRLQEGVPETIAALRSAGIVIWVLTGDKQETAVNIAYSCRLFSTDMEVITLNARSQEATEETIRFYLEQVDRCLTCFTADMEESQRRRSFSTLLSRLANFLFGRRGPVRSEPVDDTQPKFGASLRHRKKRALVIDGRTLSFILERSADQL---FLRLAQQCSVVLCCRATPLQKACVVNLVKDRLNVLTLAIGDGANDVSMIQAADIGVGISGQEGMQAVMASDFALARFRYLERLLLVHGHWCYDRLARAVVYFFYKNAAFIFILFWYQLYCGFTGAVMIDQLYLMLYNVLFTSLPPLILGIYDQDCPAHLLLKRPALYTPGRKSKTYTKYSFWVNMLDALYQSIIIFFVPFFVYYDSDVDIWEFGTTICTACFCVQML-HVAIECKSWTLMHGMSIVASFFVYFGFAL-LYNSVC---YDSPTLQNPYWVMQHAMSTAQFWLCLLLIPVISCLPRFVVRAL 1277          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF---EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDI----EKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTD-NPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            +ESPDE ALV+     G  L  R+ ++L++         V  +L  LPF S RK MSV+V+   TG++ +  KGAD+V+  ++   S  D    EI+ +T+  +  YA  GLRTL + KR L+E EY+ W +  +  E ++ N E  + E    +E+NL L+GA G+ D+LQE VPE +E  + AGI +W+LTGDK+ETA++IA + +L    + +   +C+S+      + +++ DI    E+ L D     +E       F LVIDG +L   L  D L++ FL +   C  V+CCR TP+QK +VV LV     V +LAIGDGANDV+MIQ AD+G+G+SG+EG QA ++SDFAI++FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F++Q   G+S S   +    + F+L+ T +PP+++GV DKD S   LL+ PQ+Y  G NS+ Y P  FW T+LD+ +QSLV F +P   Y +++I +  FG       ++ +  H +IESR  +  H  + +G+    FY    ++ SL  V   CN   NPY V    MS    Y +  L+T ++L PR
Sbjct:  694 AESPDEAALVQAARAYGCTLLGRSPEQLLVALPGTGPLSV-PLLHLLPFHSARKRMSVVVRHPLTGQVVVYTKGADNVIM-ELAGTSAADGCSREIMEKTQQHLDNYAREGLRTLCVAKRALDEAEYEAWLKRHAFAETSIENREQLLLESAQRLETNLTLLGATGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAVNIACACKLLRPTDQLLTANCDSKEACEARLYELQRDISTSIERGLPDRSAVTSEDQAAVSGFTLVIDGRTLDFALEED-LQKLFLDVTGNCRSVICCRSTPLQKSQVVRLVGDSLGVMSLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDFAISRFKHLRKLLLVHGHWCYTRLANMILYFFYKNVMYVNLLFWFQFFCGYSGSTMTNSWVLIFFNLLFTSVPPLLYGVLDKDVSANTLLSLPQLYKAGQNSQAYLPCTFWLTMLDAFYQSLVCFFIPYFAYADSDIGLFSFGSPINGSALLIILLHQVIESRTLTWIHAVVFLGS--AAFYYTFVLVFSLTCV--TCNPPTNPYGVETRAMSHPSYYFVCGLTTILALLPR 1273          

Query:  231 ESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEEN 1433
            + K   N+IRTTKY F +FI  NLFEQ  R++N++FIF   LNF+P V AF    +IIPI+ ++ VT +KD  ED RR  SDR VNN     YD+    +   +W ++ VGD+++L   E IPAD+++ +SSD +G+C IET ++DGET LKQR V+++L    +       +   E E  N  + +F G  +     K    L+  NL+LR  I+RNT  V GIV+YAG++TK   NN   R+KRS LE +LNVD+L  + IL+++C+   IG   +L  F    + +F+  + T      L GF  FWT IIV Q +IP++LY+++E+VK  QI  I NDL LY+  +D  +  +A NITEDLGQI+ +F DKTGTLT+N M+FR  ++ G  Y   EN
Sbjct:   38 QRKYSGNKIRTTKYTFLSFIPKNLFEQLHRFANVYFIFLAALNFVPIVNAFQPEISIIPIILVMSVTAVKDLWEDQRRRKSDRQVNNLLCDAYDRKQRRYVERRWAEVCVGDVVRLCCNEIIPADMVLLHSSDTNGVCHIETANLDGETNLKQRQVVRNLPQQGSEFTPENFSSRIECENPNDDLRRFRG--YMEHPNKVKVGLHSENLLLRSCIVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNVDVLWSVVILLLMCLTAAIGHGLWLNSFE--DHPVFLIPDDT---HPALAGFYMFWTMIIVLQVLIPVSLYVSIEIVKLGQIYFIQNDLDLYNPKLDSGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVSGTEYPHHEN 431          

Query:  219 PLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCV-CKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFK-NYYFEVEASNKQIYKFNGKIFDHRIGKSV-QHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFW-----TGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQ--LLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIY--LTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGT-LGIGFYL 3434
            P   E K   N I+  KY    F+   L++QFK + NL+F+      F+P +      T   P+ F+L VT++++ V+++RRY  D+ +N++    Y K+     +  K  DI VGD+I +   +RIPAD++   +S+ +G CFI T  +DGET  K +  + +       L ++F  + Y   +     I+ F G          + + L+  N +   T++  +  V G+VIY G +T+  +N  Q++ K  LL+ +LN                             ++   +F+      +  V LQGFI  W       +++F  IIPI+L + L++ K+         L + DE++   + V+   I E++G++  +  DKTGTLT NEM+F+   +   +Y T+  D          E+ +  HI+Q    + SA  N +  A S    K          S+++      K  +                   +  P+ + L      + ES ++   Y   N T                   + SPDE ALVR     G  L  R    L +      + + + IL+  PF S  K M +IV+D ATGEI+   KGAD  M   +  N   + E  N         A  GLRTLV+ K+ L+E +Y+ +E   ++ + +L +   ++  + + +E  ++L+   G+ED+LQ  V   LE  + AGI IW+LTGDK ETA  IA S+ L S+++ +            +V   +    E  L     E N    KH +  LVI G SL V L   E   EF+ +A  C  VVCCRC+P QK ++V L++++   RT AIGDG NDV+MIQ AD GIG+ GKEG QA+LA+DF+IT+FK++ RL++VHG  SY + A +   + ++ MIIS +   +  +  F++         + +  I T + P+   V D+D   E+ L  P++Y  LT   S  ++    W  +L S++Q  ++    +L  ++ E        IS + +V+     + +  R W   HW + +     +G YL
Sbjct:  110 PEKCEEKYPKNAIKNQKYNILTFVPGVLYQQFKFFLNLYFLVVACSQFVPSLKIGYLYTYWAPLGFVLAVTMVREAVDEVRRYRRDKEMNSQ---LYSKLTVRGKIQVKSSDIQVGDLIIVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDWKLKIAV-ACTQRLPALGDLFSVSAYVYAQKPQLDIHSFEGNFTREDCDPPIHESLSIENTLWASTVV-ASGTVIGVVIYTGKETRSVLNTSQSKNKVGLLDLELN-----------------------------RLTKALFLAQVVLSVVMVALQGFIGPWFRNLFRFVVLFSYIIPISLRVNLDMGKSAY-----GWLIMKDENIPGTV-VRTSTIPEEMGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMD----------EIQS--HIIQSYAQVTSAPANGSS-ASSTPSRKPPPSAPKVRKSVSSRIHEAVKAIAL----------------CHNVTPVYESLANGASAEPESTEADRDYSDDNRTYQ-----------------ASSPDEVALVRWTESVGLTLVNRDLTSLQL-KTPAGQILTFCILQIFPFTSESKRMGIIVRDEATGEITFYMKGADVAMASIVQYNDWLEEECGNM--------AREGLRTLVVAKKSLSEEQYQDFESRYNQAKLSLHDRGLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSRSQDI------------HVFRPVSNRGEAHL-----ELNAFRRKH-DCALVISGDSLEVCLRYYE--HEFVELACQCPAVVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFKHIGRLLVVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGFLMVGYATIYT-MFPVFSLVLDQDVKPEMALLYPELYKDLTKGRSLSFKTFLIW--VLISVYQGGILM-YGALVLFDQEFV--HVVAISFTALVLTELLMVALMVRTW---HWLMVVAEFFSLGCYL 1070          

Query:  219 PLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCV-CKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFK-NYYFEVEASNKQIYKFNGKIFDHRIGKSV-QHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFW-----TGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQ--LLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIY--LTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGT-LGIGFYL 3434
            P   E K   N I+  KY    F+   L++QFK + NL+F+      F+P +      T   P+ F+L VT++++ V+++RRY  D+ +N++    Y K+     +  K  DI VGD+I +   +RIPAD++   +S+ +G CFI T  +DGET  K +  + +       L ++F  + Y   +     I+ F G          + + L+  N +   T++  +  V G+VIY G +T+  +N  Q++ K  LL+ +LN                             ++   +F+      +  V LQGFI  W       +++F  IIPI+L + L++ K+         L + DE++   + V+   I E++G++  +  DKTGTLT NEM+F+   +   +Y T+  D          E+ +  HI+Q    + SA  N +  A S    K          S+++      K  +                   +  P+ + L      + ES ++   Y   N T                   + SPDE ALVR     G  L  R    L +      + + + IL+  PF S  K M +IV+D ATGEI+   KGAD  M   +  N   + E  N         A  GLRTLV+ K+ L+E +Y+ +E   ++ + +L +   ++  + + +E  ++L+   G+ED+LQ  V   LE  + AGI IW+LTGDK ETA  IA S+ L S+++ +            +V   +    E  L     E N    KH +  LVI G SL V L   E   EF+ +A  C  VVCCRC+P QK ++V L++++   RT AIGDG NDV+MIQ AD GIG+ GKEG QA+LA+DF+IT+FK++ RL++VHG  SY + A +   + ++ MIIS +   +  +  F++         + +  I T + P+   V D+D   E+ L  P++Y  LT   S  ++    W  +L S++Q  ++    +L  ++ E        IS + +V+     + +  R W   HW + +     +G YL
Sbjct:   88 PEKCEEKYPKNAIKNQKYNILTFVPGVLYQQFKFFLNLYFLVVACSQFVPSLKIGYLYTYWAPLGFVLAVTMVREAVDEVRRYRRDKEMNSQ---LYSKLTVRGKIQVKSSDIQVGDLIIVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDWKLKIAV-ACTQRLPALGDLFSVSAYVYAQKPQLDIHSFEGNFTREDCDPPIHESLSIENTLWASTVV-ASGTVIGVVIYTGKETRSVLNTSQSKNKVGLLDLELN-----------------------------RLTKALFLAQVVLSVVMVALQGFIGPWFRNLFRFVVLFSYIIPISLRVNLDMGKSAY-----GWLIMKDENIPGTV-VRTSTIPEEMGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMD----------EIQS--HIIQSYAQVTSAPANGSS-ASSTPSRKPPPSAPKVRKSVSSRIHEAVKAIAL----------------CHNVTPVYESLANGASAEPESTEADRDYSDDNRTYQ-----------------ASSPDEVALVRWTESVGLTLVNRDLTSLQL-KTPAGQILTFCILQIFPFTSESKRMGIIVRDEATGEITFYMKGADVAMASIVQYNDWLEEECGNM--------AREGLRTLVVAKKSLSEEQYQDFESRYNQAKLSLHDRGLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSRSQDI------------HVFRPVSNRGEAHL-----ELNAFRRKH-DCALVISGDSLEVCLRYYE--HEFVELACQCPAVVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFKHIGRLLVVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGFLMVGYATIYT-MFPVFSLVLDQDVKPEMALLYPELYKDLTKGRSLSFKTFLIW--VLISVYQGGILM-YGALVLFDQEFV--HVVAISFTALVLTELLMVALMVRTW---HWLMVVAEFFSLGCYL 1048          

Query:  219 PLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCV-CKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFK-NYYFEVEASNKQIYKFNGKIFDHRIGKSV-QHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFW-----TGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQ--LLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIY--LTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGT-LGIGFYL 3434
            P   E K   N I+  KY    F+   L++QFK + NL+F+      F+P +      T   P+ F+L VT++++ V+++RRY  D+ +N++    Y K+     +  K  DI VGD+I +   +RIPAD++   +S+ +G CFI T  +DGET  K +  + +       L ++F  + Y   +     I+ F G          + + L+  N +   T++  +  V G+VIY G +T+  +N  Q++ K  LL+ +LN                             ++   +F+      +  V LQGFI  W       +++F  IIPI+L + L++ K+         L + DE++   + V+   I E++G++  +  DKTGTLT NEM+F+   +   +Y T+  D          E+ +  HI+Q    + SA  N +  A S    K          S+++      K  +                   +  P+ + L      + ES ++   Y   N T                   + SPDE ALVR     G  L  R    L +      + + + IL+  PF S  K M +IV+D ATGEI+   KGAD  M   +  N   + E  N         A  GLRTLV+ K+ L+E +Y+ +E   ++ + +L +   ++  + + +E  ++L+   G+ED+LQ  V   LE  + AGI IW+LTGDK ETA  IA S+ L S+++ +            +V   +    E  L     E N    KH +  LVI G SL V L   E   EF+ +A  C  VVCCRC+P QK ++V L++++   RT AIGDG NDV+MIQ AD GIG+ GKEG QA+LA+DF+IT+FK++ RL++VHG  SY + A +   + ++ MIIS +   +  +  F++         + +  I T + P+   V D+D   E+ L  P++Y  LT   S  ++    W  +L S++Q  ++    +L  ++ E        IS + +V+     + +  R W   HW + +     +G YL
Sbjct:  110 PEKCEEKYPKNAIKNQKYNILTFVPGVLYQQFKFFLNLYFLVVACSQFVPSLKIGYLYTYWAPLGFVLAVTMVREAVDEVRRYRRDKEMNSQ---LYSKLTVRGKIQVKSSDIQVGDLIIVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDWKLKIAV-ACTQRLPALGDLFSVSAYVYAQKPQLDIHSFEGNFTREDCDPPIHESLSIENTLWASTVV-ASGTVIGVVIYTGKETRSVLNTSQSKNKVGLLDLELN-----------------------------RLTKALFLAQVVLSVVMVALQGFIGPWFRNLFRFVVLFSYIIPISLRVNLDMGKSAY-----GWLIMKDENIPGTV-VRTSTIPEEMGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMD----------EIQS--HIIQSYAQVTSAPANGSS-ASSTPSRKPPPSAPKVRKSVSSRIHEAVKAIAL----------------CHNVTPVYESLANGASAEPESTEADRDYSDDNRTYQ-----------------ASSPDEVALVRWTESVGLTLVNRDLTSLQL-KTPAGQILTFCILQIFPFTSESKRMGIIVRDEATGEITFYMKGADVAMASIVQYNDWLEEECGNM--------AREGLRTLVVAKKSLSEEQYQDFESRYNQAKLSLHDRGLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSRSQDI------------HVFRPVSNRGEAHL-----ELNAFRRKH-DCALVISGDSLEVCLRYYE--HEFVELACQCPAVVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFKHIGRLLVVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGFLMVGYATIYT-MFPVFSLVLDQDVKPEMALLYPELYKDLTKGRSLSFKTFLIW--VLISVYQGGILM-YGALVLFDQEFV--HVVAISFTALVLTELLMVALMVRTW---HWLMVVAEFFSLGCYL 1070          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDF---EIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDI----EKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESR 3374
            +ESPDE ALV+     G  L  R+ ++L++         V  +L  LPF S RK MSV+V+   TG++ +  KGAD+V+  ++   S  D    EI+ +T+  +  YA  GLRTL + KR L+E EY+ W +  +  E ++ N E  + E    +E+NL L+GA G+ D+LQE VPE +E  + AGI +W+LTGDK+ETA++IA + +L    + +   +C+S+      + +++ DI    E+ L D     +E       F LVIDG +L   L  D L++ FL +   C  V+CCR TP+QK +VV LV     V +LAIGDGANDV+MIQ AD+G+G+SG+EG QA ++SDFAI++FK+L++L+LVHGH  Y +LA M L  FYKN++   ++F++Q   G+S S   +    + F+L+ T +PP+++GV DKD S   LL+ PQ+Y  G NS+ Y P  FW T+LD+ +QSLV F +P   Y +++I +  FG       ++ +  H +IESR
Sbjct:  724 AESPDEAALVQAARAYGCTLLGRSPEQLLVALPGTGPLSV-PLLHLLPFHSARKRMSVVVRHPLTGQVVVYTKGADNVIM-ELAGTSAADGCSREIMEKTQQHLDNYAREGLRTLCVAKRALDEAEYEAWLKRHAFAETSIENREQLLLESAQRLETNLTLLGATGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAVNIACACKLLRPTDQLLTANCDSKEACEARLYELQRDISTSIERGLPDRSAVTSEDQAAVSGFTLVIDGRTLDFALEED-LQKLFLDVTGNCRSVICCRSTPLQKSQVVRLVGDSLGVMSLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDFAISRFKHLRKLLLVHGHWCYTRLANMILYFFYKNVMYVNLLFWFQFFCGYSGSTMTNSWVLIFFNLLFTSVPPLLYGVLDKDVSANTLLSLPQLYKAGQNSQAYLPCTFWLTMLDAFYQSLVCFFIPYFAYADSDIGLFSFGSPINGSALLIILLHQVIESR 1238          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEEN 1433
             N IRTTKY   +FI +NLF+QF R +NL+F+F V+LN++P V AF +   +IP+  +LIV   KD +ED RRY  D+ +NN     Y      +   +W ++ VGD+++L   E IPAD+++ +SSD +G+C IET ++DGET LKQR V+++L    +       +   E E  N  + +F G  +     K    L+  NL+LR  I+RNT  V GIV+YAG++TK   NN   R+KRS LE +LNVD+L  + IL+++C+   IG   +L  F    + +F+  + T      L GF  FWT IIV Q +IP++LY+++E+VK  QI  I NDL LY+  +D  +  +A NITEDLGQI+ +F DKTGTLT+N M+FR  ++ G  Y   EN
Sbjct:   73 GNGIRTTKYTLLSFIPMNLFQQFHRAANLYFLFLVLLNWVPVVEAFQKEITMIPLAVVLIVIAFKDAMEDYRRYRYDQRINNTLTHVYSGKQRRYVERRWAEVCVGDVVRLCCNEIIPADMVLLHSSDTNGVCHIETANLDGETNLKQRQVVRNLPQQGSEFTPENFSSRIECENPNDDLRRFRG--YMEHPNKVKVGLHSENLLLRSCIVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNVDVLWSVVILLLMCLTAAIGHGLWLNSFED--HPVFLIPDDT---HPALAGFYMFWTMIIVLQVLIPVSLYVSIEIVKLGQIYFIQNDLDLYNPKLDSGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVSGTEYPHHEN 461          

Query: 1485 HILQLLLLSAICNTTIIAKSNQ---REKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPK--SNITADNFPHRHLTNEELSPLIL---SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVM---FPKIIANSDKD---FEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETV---------KXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTC-----KHKEFV------LVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLE-LFIL--NSLCVVLLDCNT-DNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIK 3590
            +++   +  AICNT +++  NQ   ++KK   V S    L  +      ++       S            +    P      +  KAE+ + VS  P   S + A +     ++N  L    L   +ESPDE ALV       F L  ++ D++II +      + +++L  + FDS RK MSV+V+   T E+ +  KGAD+V+         NSDKD    ++  +T+AD+  YA +GLRTL + KR L ++EY  W ++  + E  +   E  + E    +E ++ L+GA G+ED+LQ+ VPE +   ++AG+ IW+LTGDK+ETAI+IA+S +L   ++ +         +          +     +R+  E    + + E   +       +++  V      LVIDG +LS  L  D L+E FL +   C  V+CCR TP+QK  VV LV++  +V TLAIGDGANDV+MIQ AD+G+G+SG+EG QA ++SD+A+ +F++L +L+LVHGH  YD+LA M L  FYKN     ++F+YQ   GFS S  IDQ   ++F+L+   LPP++ GV DKD S E LLA P +Y  G NS  YRP  FW T++D+L+QS+V F +P L Y  +++ +  +G    +  + ++  H+ IE++ W+  HW    G++ +   L  LF+L  N++C+   +C    NPY ++   M++   YL+  ++  ++L PRL+ +
Sbjct:  554 NVVDFFITLAICNTVVVSSPNQPRIKKKKASGVTSPMKKLEEMMKKLTPLRLSSVTPSSSFSLHSKAADKSNALYSPAAYRDNLQAKAETGRPVSHPPTPCSPLAAKSLAA-GMSNGVLPTAELRYEAESPDEAALVYAARAYNFTLVSKSPDQVII-DVPHVGRLTFDLLHVMAFDSTRKRMSVVVRHPLTDEMVVYTKGADNVIMDILKPCTGNSDKDKAKAKMHARTQADLNQYAMDGLRTLCIAKRELTDDEYATWAKSHLEAEAAIDCREEMLFESALRLERDMQLLGATGIEDRLQDGVPETIAALRDAGLQIWVLTGDKQETAINIAFSCKLLDASDEIITLNTESLSRGQHRHRTLCSLASTGGVRQAAEAVAPEQELERGGRGAVICDGRYRGTVVTTRRGLVIDGKTLSFALNKD-LEENFLKLTRDCRSVLCCRSTPLQKSMVVKLVREKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDYAMPRFRHLHKLLLVHGHWCYDRLANMVLYFFYKNAAFVTLLFWYQFFCGFSGSSQIDQWYLMLFNLLFCSLPPLVTGVLDKDVSAETLLARPHLYQNGQNSLAYRPILFWVTMMDALYQSMVCFFLPYLAYRGSDVDIFTWGTPITTVSLFSILLHLAIETKTWTWIHW----GSIALSLLLYFLFVLAYNAICI---NCAAPSNPYMIMEILMTQPLFYLVCVVTPLVALLPRLVYR 1283          

Query:  243 VNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIF---DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSI-IPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCC--DSENE 1466
             +N I+TTKY  ++F+  NLFEQF R++N++F+F V+LNF+P V AF  G A++P+ FIL VT +KD  ED RRY SDR +NN P L Y +    F    WKD+ VGD +KL   E IPAD+L+  SSDP G+C +ET ++DGET LK R ++K   +   + + +      E E  N  + KF G +    + ++G     L+  NL+LR   +RNT  V GIV+Y G++TK  +NN   R+KRS LE  +N+D++ C+ ILI++C+   I    ++ G+ +       + + + I  V L GF  FWT II+ Q + IPI+LY+++E+VK  QI  I  D  LYD   D  +  +A NITEDLGQIK +F DKTGTLT+N+M+FR  ++ GK Y    N  RL    DSE++
Sbjct:   48 ASNAIKTTKYTVWSFLPKNLFEQFHRFANVYFVFIVLLNFVPVVNAFQPGLAVLPVAFILAVTAVKDLWEDYRRYHSDREINNAPCLVYCRAQQGFIERCWKDVRVGDFLKLRCNEIIPADVLLMASSDPDGLCHLETANLDGETNLKLRQLVKGFADLDCDFDPMKYTSIVECERPNNDLNKFKGFMLHSNERKVG-----LSKDNLLLRGCTVRNTEYVVGIVVYGGHETKAMLNNNGPRYKRSKLERNMNMDIIWCVIILIVMCLFIAIAHGLWMAGYEENPPFDVASKDGSHISPV-LSGFYMFWTMIIILQQVLIPISLYVSIEIVKIGQIYLIHQDEELYDPESDTPLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVAGKEYSHSNNAQRLAAYQDSESD 455          

Query: 1800 HRHLTNEELSPLIL-SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIRE--DIEKSLFDSKRENN--EKTCKHKEFVLVIDGCSLSVILTSDELK--------------------------------EEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMG-------EFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNS 3455
            H  +  E+   LI  ++SPDE ALV      G+    RT + + I      +  VYE+L  L F+S RK MSVIV+ +  G++ L CKGAD+V+  ++     KD      T+ D+  +A+  LRTL +  + L+E EY  W +   +   +L + E +   +Y+ IE+NL L+GA  +EDKLQ+ VPE +     A I IW+LTGDK+ETA +I Y+  L +++  +         E+  ++S ++E   I++    ++ E +  ++  K K+  ++I G  L+ ILT ++ K                                + F+ +A  C  V+CCR +P QK  VV +V K+ +  TLAIGDGANDVNMI+TA IG+G+SG+EG QA L+SD++  +F++L+RL+LVHG  SY ++ +     FYKN   +LV F++   +GFS     D     +++++ + LP ++ G++D+D SD      P++Y TG  +  +  + F R ++  +  SL+IF +P   +  T  S G        F +++ + + + +   I +++  W+  +     G++ + F + +F L+S
Sbjct:  501 HTVMAEEKEGDLIYQAQSPDEGALVTAARNFGYVFLDRTLESVTIVELGTER--VYELLNILDFNSDRKRMSVIVR-SPEGKLRLYCKGADTVILERL----QKDDPNRESTEKDLNTFAAESLRTLCLSYKDLSEEEYLDWSKKYEQASMSLTDREKKQGLVYEKIETNLKLLGATAIEDKLQDGVPEAIAKLAAAKIKIWVLTGDKQETAENIGYACHLLTEDMQI-----CYGDEVSTMLSDVQECQTIKRDAKGNEEEVDFAKQFLKGKKNAIIITGGCLNGILTDNKQKRLDRLKLPRRRKPREQREEEKQREILKRERIEKRFVSLACACEAVICCRVSPRQKARVVRMVMKHKQAVTLAIGDGANDVNMIKTAHIGVGISGQEGMQAVLSSDYSFAQFRFLERLLLVHGRWSYLRMCKFLQYFFYKNFAFTLVHFWFSFFNGFSAQAVYDDWYITLYNMLYSALPVLVMGLFDQDVSDSKSFKFPELYETGQKNLNFNYKIFGRCLIQGIITSLIIFFIPYGAFLETMRSDGLAPDDYQSFAVVTATSLTLIVNLQIGLDTAFWTYLNTFSIFGSIALYFAI-MFDLHS 1083          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLN-EFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFK-NYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYL----RGFNK----IQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLR 1442
             N I+T KY    F+ +NL EQF+R +N++F+F +IL  IP + +    T  +P++ +L +T IKD V+D+ R+ SD+ +NNR   + + M N  F   KW +I VGD+++L   + +PAD+L+  +++P+ +C++ET ++DGE+ LK +  +    NN T+ +++ + +     EA N ++ K+ G +   +    +  L+   L+LR   +RNT    G+VI+AG  TK+  N+ + +FKR+ ++ Q+N  + M  G+L+++     IG + +     +GF K    I     + S  TV       GF+ FW  II+  +++PI+LY+++E+++  Q   I  DL +Y +  D   + +   + E+LGQI+ +F DKTGTLT N M F+  SI G  +   E+  R
Sbjct:   47 GNYIKTAKYNIVTFLPMNLLEQFQRVANVYFLFLLILQAIPIISSLAWYTTFVPLVIVLSITAIKDAVDDISRHRSDKQINNR---KCEIMQNGSFKEDKWMNIQVGDLLRLKKNDFVPADMLLLSTTEPNSLCYLETAELDGESNLKFKQALTVTHNNLTDEKQLAEFDAIIMSEAPNNRLDKYLGTM---QWKDKMYSLDNDKLLLRGCRIRNTETCHGLVIFAGFDTKIMKNSGETKFKRTQIDKQMNKIVFMIFGMLLVMATGLAIGNTIWEVVHGQGFGKYCSGITGDPAVPSPDTVSEWAVWTGFLNFWGYIILLNTVVPISLYVSVEVIRLGQSFFINWDLRMYFKVNDTPSNARTTTLNEELGQIEYIFTDKTGTLTQNIMTFKKCSISGMAFGGCEDTWR 449          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFS-QNETVKXXXXXXXXXXXNVMSQIRED----------------IEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVN--MIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYW------NTEISMGEFGIISVSCVVIAMFSHIM-IESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIK-HDPHIFDYKNSKFYLGNLEEFKKL 3767
            ++SPDE ALV       F    RT + + +    + +   Y++L  L F++ RK MSVIV+ NA G + L CKGADSV+F ++   +    +++N T   + A+A  GLRTL +  R L+E  +++W+E   +   +L   E  +  +YD IE N+ L+GA  +EDKLQE VPE +     A I IW+LTGDK+    +  Y + L S   + V  I   S   ++  +  I E                 + K             C  +    V +G +L+V L +  LK++FL      +  V  R T            ++   + + + DG    N  +I+TA IG+G+SG+EG QA L+SD++  +F++L+RL+LVHG  SY ++ +     FYKN   +LV F++    GFS     DQ    +F+++ T LP +  GV+D+D +D+  +  P++Y  G  + ++  R+F+  I   ++ S+V+F VP   +        T +S  +   ++VS  +I + S  M +++ +W+  +     G++ + F + +F + S  +  +  +          T+++   +L+IAL+T + + P    +    + R ++  +   R  +   RK      +T++ H  H    + S +   + E F +L
Sbjct:  463 AQSPDEGALVTAARNFDFVFRSRTPETITLHELGEPR--TYQLLAILDFNNFRKRMSVIVR-NAEGRLKLYCKGADSVIFERLHPCNQ---QLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQEGVPETIAKLALANIKIWVLTGDKQAATRAAFYRSSLISIVRKNVHLILMSSLLTVLCFIHPINERSVEPLHGVFISSTLGRLHKMAVVVMVVVIVADCAGR----VCNGVNLAVRLGA-VLKDDFLAAVASNHSSVALRLT----ANSESENTRFVAKQWIGLNDGRPSHNCIVIETAHIGVGISGQEGMQAVLSSDYSFAQFRFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFNKREFFICIGQGIYTSVVLFFVPYAAFVEAVRDDGTGLSDHQSLAVAVSTSLIIVVSLQMGLDTAYWTAINHFFIWGSVAVYFAI-MFAMYSAGLYSIFPSQFRFIGTARNTLNQPSVWLVIALTTIVCIMPIAAFRFLKTDLRPTLSDKTQERYMQRQRRK---QKPQTLRLHRVHRTGSRRSGYAFAHQEGFGEL 1112          

Query:  249 NRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRY--DKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFE----VEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCL-GILIIVCIMTGIGCSF-----------YLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            NRI+T+KY    F+ +NLFEQF+R +N +F+F +IL  IP++ + +  T I+P++ +L +T +KD  E+  R+ SD  VNNR    +   K+ NE    KW ++ VGD+IK+ + + + ADLL+  SS+P  +C+IET ++DGET LK R   ++L   S   +++ K  +F+     E  N ++ +F G ++      +   L+   ++LR  +LRNT    G+V++AG  TK+  N+ + + KR+ ++  +N  +L  + G L+ +  + G+G +            YL   + + + IF              GF+ FW+ II+  +++PI+LY+++E+++      I  D  +Y    D   +V+   + E+LGQI+ +F DKTGTLT N M F   SI G+ Y
Sbjct:    2 NRIKTSKYNVVTFLPVNLFEQFQRVANAYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDASEEYFRHRSDNQVNNRQSQVHINGKLQNE----KWMNVRVGDIIKMENNQFVAADLLLLSSSEPHSLCYIETAELDGETNLKVR---QALPVTSQIADDIDKLAHFDGEVICEPPNNKLDRFTGTLYWR---GNTYSLDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMNTLVLWWIFGFLVCMGSILGLGNTIWESAIGYYFQPYLPWESAVDSAIF-------------SGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYGKRDTPAEVRTTTLNEELGQIEYIFSDKTGTLTQNIMTFNKCSINGRVY 386          

Query:  261 TTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSEN--EELH-NNPH---ILQLLLLSAICNTTI 1532
            T KY    F+   L+EQF R +NLFF+F  +L  IPEV    + T ++P++FIL+V  +K+ +ED +R+ +DR VN +   +  +   ++    W+ + VGD++++++ + +PADL++  SS+P  MC+IET ++DGET LK R  +       T+   +  +   E EA N+ +Y F G I     G     L    ++LR   LRNT  V G+V+Y G+ TK+  N+ +A  KRS ++   N+ +L+ +  L+++ + + IG S +     K    +    N    +     GF  F T II++ ++IPI+L +TLE+VK  Q   I  D  +Y E  +     +  N+ E+LGQ+K +F DKTGTLT N M F+ A++ G  Y   E    +        + LH N+P    I + L++ ++C+T +
Sbjct:    2 TAKYNALTFLPRFLYEQFSRAANLFFLFIALLQQIPEVSPTGRYTTLMPLIFILVVAALKEIIEDYKRHRADREVNKKKTTQVLQN-GDWHTVSWEKVGVGDVLRITNGQNLPADLVMLSSSEPQAMCYIETANLDGETNLKIRQGLPLTAGLQTSDSLLSIDGRIECEAPNRHLYDFTGNI--QLQGHGTVPLGPDQILLRGAQLRNTQWVFGVVVYTGHDTKLMQNSTRAPLKRSNVDRVTNLQILLLVVTLLLMALASAIGSSIWTSAHWKGDWYLGFRDNAPSNF-----GF-NFLTFIILYNNLIPISLLVTLEVVKFIQAFFINWDSEMYHEESNTNAMARTSNLNEELGQVKYIFSDKTGTLTCNVMEFKKATVAGIAYGHNEEPSEVGFQDPALLQNLHSNHPSAGVIYEFLVMMSVCHTAV 422          

Query: 1818 EELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANS 2102
            E+ S +  + SPDE ALVR     GF    RT + ++I +A  ++   +E+L  L F S+R+ MSVIV+   +G++ L CKGAD+ ++ ++  NS
Sbjct:  426 EDGSIVYQASSPDEGALVRAARSLGFTFTVRTPNMVVI-DALGQEQ-NFELLHVLEFTSVRRRMSVIVR-TPSGKLRLYCKGADNAIYERLANNS 517          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQ 3167
            + SPDE ALV    Y G+    R  D  I       K ++Y++L  + F S RK M++IV+     +I + CKGADS++  ++      D +++  T   + +YAS GLRTL++ ++ L+E EY+ ++E       ++I  + +++E+ D     L++VG   +EDKLQ+ V + +   K+AGI +W+LTGDK ETAI+I +S +L                        + + +E  + D   +   +T        V+ G SL  I     + ++FL +A   + ++ CR +P QK ++V L+        TLAIGDGANDVNMI  A IG+G+SG EG QA  ASD+AI +FK+LK L+ VHG  SY K + +    FYKN++  +  F++   S FS     ++    IF++I T  P IIF ++D+  S    + NP+
Sbjct:  371 ASSPDELALVNCGKYFGYFFKGRDDDNNIEVEV-NGKSVIYQLLGVIEFSSDRKRMTIIVR-TPENKIMVLCKGADSIVQARL-----SDSKVLGATVQHLESYASGGLRTLLLAEKELSEAEYQNFKEEYRVAASSMIKRDEKMEEVAD----RLEIVGTTAIEDKLQDDVDKAIFAMKKAGIKVWVLTGDKIETAINIGFSCQL------------------------LNDKMELYVIDGASKEGLRTSG-----TVVSGESLFKI----RITKQFLKLACSSSVLIACRMSPKQKADIVRLIIANNPSLITLAIGDGANDVNMINAAHIGVGISGVEGQQAVSASDYAIGQFKFLKNLLFVHGRESYRKNSYLVCYTFYKNVLFVMPQFWFGFYSAFSGQVFYEKWIYQIFNIIFTAFPIIIFALFDQQKSRHHFMQNPK 769          

Query:  387 QGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQH-LNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENE--ELH----NNP---HILQLLLLSAICNTTI 1532
            Q T ++P++F++ V+ +KD  ED++R+ SD   N R VLR DK    F +  WK++ VG +I++   +  PADL +  S++ +G+ ++ET ++DGET LK +  +      +T     F+      EA N     F G +   +   +V + L+  +++LR T LRNT  V GIVIY G+ +K+  N+ ++R K S    + N  +++   +L++  + +G+     L       + + +    T I D       +F T +++F + +PI+L +TLE+VK         D  +YD +     D+   N+ E LGQ+  +F DKTGTLT N M ++  S+   +Y  +   +    + ++E  E H    N+P   +I   L   AIC+T +
Sbjct:    2 QPTILLPLMFVITVSAVKDIFEDMKRHKSDNVENTRKVLRLDKKTKTFVLDSWKNLRVGQIIQVRQDQYFPADLALLRSANNNGIAYVETKNLDGETNLKHKAAVVDASACTT-----FRG-TLTCEAPN----DFEGTV---KTADNVTYSLDHNSILLRGTSLRNTEWVYGIVIYTGHDSKIMKNSSKSRTKFS----KTNKQIILSFSLLVLHSMNSGLS---ELVKLTTHTSTLLVRMTLTRISD----SVTRFGTWLLLFANFVPISLIVTLEVVK------FLWDAEIYDVAK----DLNTKNLNEQLGQVDYVFSDKTGTLTCNLMEYKKHSVGKYSYGVDGAQITDGVEKDDEIFEAHMNDKNHPNYKNIQNFLTHLAICHTVV 359          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVK-----DNATGEISLNCKGADSVMFPKIIANSDKDFE-IINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLF----------SQNETVKXXXXXXXXXXXNVMSQIREDI------EKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGE---------FGIISVSCVVIAMFSHIMIESRHWSVF 3389
            ++SPDE ALV      GF+   +T+  LII     +K   +EIL  L F+S RK MS IVK             L CKGADS+++ ++   S  + E I+ +T   +  YA+ GLRTL + +R L+ +EY+KW E       +L N E+E++ + D IE  L L+G   +ED+LQ+ VP+ +E   EAGI +W+LTGDK ETAI+I +S  L           +  + VKE   E    +  ++S+  ++       E+ +F++K+++         + +VIDG +L + L  ++++ +FL +   C  V+CCR +P QK  VV LVK   +V TLAIGDG+NDV MIQ+AD+GIG++G+EG QA + SD+AI +F+YL RLVLVHG  SY +LA M    FYKNMI +L +F+Y I + F  S   +    + ++L  T LP I  G+ D+D +D I L  PQ+Y  GI  K +  R F   +LD L+QS++ F  P L Y    I              G+   +  VI+  +++++    W  F
Sbjct:  796 AQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQK--EFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSKYLKEYFNLTGSEEEIFEAKKDHE---FPKGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWF 1337          

Query:  510 DKMLNEFCVCK-----WKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSV---QHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            D+ L     CK     WK + VGD++++ + + IPAD+++  +SD  G C++ET ++DGET LK R  +K  +   T+ +     ++ E E  +  +Y + G +    +       + +   N++LR   LRNT    G+V++ G  TK+ +N+     K+S +  +LN  +++   +L I+C ++GI    Y   ++K     F     T+       GF+ FW  +I++QS++PI+LYI++E++K  Q   I  D+ LY+  +D     K++NI++DLGQ++ +F DKTGTLT N M F+  +I G +Y
Sbjct:  382 DRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVY---YDKKGRSRFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSY 689          

Query:  249 NRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNN 491
            N+IRTTKY    F+  N+  QF  ++N++F+  +IL      G  N G + +P++ I+I+T IKD +ED RR   D  VNN
Sbjct:  194 NKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNN 274          

Query: 1836 ILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNAT-----GEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLF----------SQNETVKXXXXXXXXXXXNVMSQ-IREDI-----EKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWN----TEISMGE-----FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNP-YKVLHYTMSRGKTYLIIALSTAISLFPRLLI 3587
            I ++SPDE ALV      G++    ++  LI+     +K   +++L  L F+S RK MS I+K   +      +  L CKGADSV++ ++   +  D  ++ +T   +  YA+ GLRTL + +R L  +EY++W +T      ++ N E E+ ++ D+IE  L L+G   +ED+LQ+ VP+ +    EAGI +W+LTGDK ETAI+I +S  +           +  E V+E   +    + N++++ +RE       E+ L ++KRE+         F ++IDG +L V L  +E++ +FL +   C  V+CCR +P QK  VV LVKK  +V TLAIGDG+NDV MIQ+AD+G+G++G+EG QA + SD+AI +F+Y+ RLVLVHG   Y +LA M    FYKN+I +L +F+Y I + F  S   +      ++L  T +P I+  V D+D SD + +  PQ+Y  GI  K +    F   +LD ++QS++ F  P L Y      TE  +G       G+   +  V +   ++ +E   W  F    C    G+   L L +      +    ++ N  YK      ++   + ++ +     L PR  I
Sbjct:  839 IKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQK--EFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRL-DRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKFGMSGSEEELKEAKREHG---LPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWF----C----GLFICLSLAVFYGWTGIWTSSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTI 1439          

Query:  474 DRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNG--KIFDHRIGK-SVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            DR +   P  R+ K         WK++ VGD++++ + + IPAD+++  +SD  G C++ET ++DGET LK R  +K      ++ +     ++ E E  +  +Y + G  K  D + G    + +N  NL+LR   LRNT    G+VI+ G+ TK+ +N      K+S +  +LN  +++   +L I+C   GI    Y +   + ++        T+       GF+ FW  +I++QS++PI+LYI++E++K  Q + I  D+ LY+  +D     K++NI++DLGQI+ +F DKTGTLT N M F+  +I G +Y
Sbjct:  427 DRTLQPNPECRFAKDY-------WKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRSRDYFEFG---TIGGSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSY 734          

Query:  249 NRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNN 491
            N+IRTTKY    F   N+  QF  ++N++F+  +IL      G  N G A +P++ I+I+T IKDG+ED RR   D  VNN
Sbjct:  232 NKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNN 312          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNE---KTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCY-WNTEISM-GE------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNP-YKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFY-EAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLK 3770
            + SPDE ALV+     G+    R  + + +      +   Y++L    F+S RK MS I +    G I L CKGAD+V+  ++    D+  + +  T   +  YAS GLRTL +  R ++E EY++W    ++    L N   ++ E  +LIE NL L+GA  +EDKLQ+ VPE +   +EAGI IW+LTGD++ETAI+I  S RL S++  +             +  + R+D E++L +     NE    T       LVIDG SL   L   EL++  L +A  C  V+CCR +P+QK  VV +VK+      LAIGDGANDV+MIQ A +G+G+SG EG QA  ++D A+ +FK+LK+L+LVHG  SY +++   L  FYKN  + +  F+Y   + FS    ++  T   ++L  T  PP + GV+D+  S  +L   PQ+Y  G   + +    FW  I++  + S ++F    L Y +   ++M GE      +G+   +  VI +     + +  W+ F      G+L   F+L  F +     +    N     Y V+ +T   G  +L     T I L    L++ FL +    ++  E +  I ++  +K+  N+S++    PH+  ++N+   +  ++  KK +
Sbjct:  650 AASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFR-FPDGSIKLFCKGADTVILERL---DDEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLI-----------INEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEP-ELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSL--LFWLIFFPI--YASIFPHANISREYYGVVKHTYGSGVFWL-----TLIVLPIFALVRDFLWKYYKRMYEPETYHVIQEM--QKY--NISDS---RPHVQQFQNAIRKVRQVQRMKKQR 1273          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLE-EVFKNYYFEV--EASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQG----------FIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY--KTEE-----------------NDLRLCCDSENEELHNNPHILQLLLLSAICNTTI 1532
            +N I TTKY F  F+   LF++F +Y+NLFF+    +  +P V   N+ T I  +L +LIV+ +K+ +ED++R  SD+ +NN     + +  ++F   +W DI VGD+I++ S E IPAD +I  SS+P G+C+IET ++DGET LK   + +S    +  ++ +  KN   +V  E  N  +Y + G +   D +I      L+   +ILR   LRNT  + G+VI+ G++TK+  N      KR+ +E  +N  ++    +LI++ +++ IG            NVI  T++   +  +YL+G          F+ FW   I+F +++PI+L++T+EL+K +Q   I +DL LY E  D    V+  ++ E+LGQI+ +F DKTGTLT N M F++ SI G  Y  K  E                 +DL+   +  ++E  ++P I   L L A C+T I
Sbjct:  200 DNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLK---IKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQI-----PLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIG------------NVIMSTADAKHLSYLYLEGTNKAGLFFKDFLTFW---ILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLKKKLNDPSDE--DSPIINDFLTLLATCHTVI 637          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXX-XXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCK-HKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVI 3257
            + SPDE A+V+     G +L +R R  + + +    K + YEIL+  PF+S  K M +IV+D    E     KGAD+VM  KI+ ++D         + +    A  GLRTLV+G++ LN+  Y+++++  +    +++N  +   + +   +E +L+L+G  G+EDKLQ+ V   +E  + AGI IW+LTGDK ETA  ++ S +L S+ + V                     I K        N  +  K ++   L+IDG SL + L   E  +EF  +      V+ CRCTP QK +V  +++K    R   IGDG NDV+MIQ AD+G+G+ GKEG QA+LA+DF+IT+F +L  L+L HG  SY + A+++  + ++ +II++    Y I S F    A+ Q   ++ +     + P+     D D  + +    P++Y      K    + F+  +L SL+Q  VI
Sbjct:  592 AASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVM-SKIVESND-------WLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHT-------------------ITKVTRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYE--QEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLF-EPIALYQGWLMVGYATCYTMAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVI 1035          

Query:  195 IYPSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNR--PVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLN-VDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVK---AHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDL-----RLCCDSENEELHNN 1481
            I+P     P+ D ++ V+N +   KY    F+   L+EQFK + NL+F+   +   +P +      + I+P+ F+L VT+ K+ ++D++R   DR  NN    V+  ++ +        KD+ VGD+IK+   +RIPADL++  SS+PSG  FI+T  +DGET  K R       N S N  ++         A  K I+KF GK+       +   L+  N +  +T+L ++      V+Y G  T+  MN   A+ K  LLE ++N +  ++C       C+      S  L  F    N  +               +I     +I+F +IIP++L + L+L K   AHQI H        D+++ + I V+   I EDLG+I+ +  DKTGTLT N+M  +   +   +Y +E  D+     +    S+N+ L+N+
Sbjct:  157 IHPDT--TPVYDRNRYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRNRSIPS------KDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSEN--DLINRISITASAPEKSIHKFLGKV--TYKDSTSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILC------ACVF---ALSILLVAFAGFHNDDW---------------YIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEH--------DKTIPETI-VRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKNDSLNNS 551          

Query: 2118 IINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEIS---MGEFGIISVSCVVIAM---FSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLH-YTMSRGKTYLIIALSTAISLFP 3575
            +I +T   I  +++ GLRTLV   + ++  +Y+ W +   + + +L + + ++ E    IE  L+L+G   +EDKLQ+ V E +E  + AGI +W+LTGDK+ETAI+I YS  L     TV             +++   E+I   +    +E +     H   V+VIDG ++++   +      F+ +    + V+CCR +P QK  +V  ++       TLAIGDGAND+ MIQ+ADIG+G++GKEG QA+  SD++I +F++L +L+ VHG  +Y + ++  L  FYK +        YQ  + FS S   +  +  +F+ + T LP +  G+++KD     LL  P++Y  G  S+ +    F   ++ +   SL+I  +  + +  + +S   M   G+I+ + +V  +      + + +R+W  F   +    L  G +L        C + +  NTD  Y V + +    GK       S  ++L P
Sbjct: 1017 VIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVV------------ILTTTDENIISKMNAVSQEVDSGNIAH--CVVVIDGATMAMFEGNPTYMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLSDNTMYPLGLINFTAIVALINVKSQFVEMHNRNWLAFTSVV----LSCGGWLVW-----CCALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLP 1487          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVN---------------------------------------NRPVLRYDK-----------------MLNEFCVC----KWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFV---MKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNG--KIFDHRIGKSVQH-LNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNN-KQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY 1418
            +NRI +++Y FY+F+   L+ QF + +N +F    +L  IP        T IIP+   + +++ ++  +D RR+  D+  N                                       N P L  D+                 + N++ V     KW+ + VGD + L+  + +PADLL+      +  CF+ETM +DGET LK +     +  L   ++ L  +  N    VE  N  +Y F G  ++ +HR    +++ L   N+I R +ILRNT  V G+VI++G +TK+ MN  K  R K   L+ ++N+ ++  + ++  + + + +G   + + +       ++      +    +       + II++ ++IP++LY+T+E++K  Q   +  D+ +Y    +   + +   I E+LGQ+  +F DKTGTLTDN+MIFR  S+ G ++
Sbjct:  140 DNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANI--NAQVTVEDPNIDLYNFEGNLELKNHRNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAGVAPTIM-------SFIIMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSLCGSSW 588          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEI--------INQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQN-ETVKXXXXXXXXXXXNVMSQIRE--------DIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHY----TMSRGKTYLIIALSTAISLFPR 3578
            +ESPDE ALV+M    G+ L  R+ + + I+       + +++L  L FDS RK MSV+V+  + G + + CKGADS +  ++   S  D  +        +NQ    +  YA +GLRTL M KR L+++EY  W     + E  L + E  ++E    +ESN++L+GA G+ED+LQ+ VPE +   +E G+ +W+LTGDK+ETAI++ Y+++L   + + +   +   +     + S +           I  S   +    + +    +   L+IDG +L   L    L E+FLH+A  C  V+CCR TP+QK  VV LV+   +V TLAIGDGANDV+MIQ AD+GIG++G+EG QA +ASDFAI +F++L +L+LVHGH  YD++ +M L  FYKN +  LV+F+YQ+ +GFS S AID ++ + F+LI T  PPI+ G+ DKD    +L  NPQ+Y  G   ++Y  + FW TILD+L+QS+++F    L +          GI      V+    H+ + +  W+  H     G++ + F   +                 P   +HY    TM+  + + +  + T  +L PR
Sbjct:  671 AESPDEAALVKMACSYGYRLLSRSPNSVTIFIP-GEGVVKFKVLHVLSFDSTRKRMSVVVRRPSDGAVLMYCKGADSAVLTRLTHASYADEAVEGGVKSTLVNQIDRHLTMYARDGLRTLCMAKRELSDSEYHDWLTEHKRAETALQHRERLLQESAQKLESNMELLGATGIEDRLQDGVPETIAKLREGGLKVWVLTGDKQETAINVGYASKLLDASMQKITLNAKNKDECSCQIYSWLNHLKIEPTVSSISGSTSYTTVSFDSRITADQPLGLIIDGPTLIYAL-EKPLNEKFLHLASRCQVVLCCRATPMQKASVVELVRDGLKVMTLAIGDGANDVSMIQMADVGIGITGQEGMQAVMASDFAIARFRFLAQLLLVHGHWCYDRITKMILYFFYKNAMFVLVLFWYQLYNGFSGSNAIDDLSLIFFNLIFTAAPPIVCGILDKDLPATLLKDNPQLYKAGQEGQLYSRKLFWATILDALYQSVILFFACFLLFEGMPADDRMVGITMHQAAVVLASVHLGLMTAQWTWIHHFFLWGSVFLSFIWAIVF-----------GVVQPTHKIHYVSLVTMATKEFWALCVMITVAALLPR 1257          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKI-----FDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYD--VYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEE-NDLRLCCDSENEE 1469
            +N+I+TTKY  ++FI  NLFEQF R++N++F+F V LN++P + AF +  A++P++F+L VT +KD  ED RRY SD+ VNN     Y      +   KWKD+ VGD+IKLSS E IPAD+L+  SSD + +C++ET ++DGET LKQR V+  L            N+  + E  N  IY+F+G I         +GK        NL+LR  I+RNT  V G+V+YAG+ TK  +NN   R K S +E  LN+D++ C+ IL  +C + G+GC  +       QN  F  ++F    +    ++GFI+FWT II+ Q +IP +LY++ ELVK  Q+  I++DL LY E  D+ +  +A NI EDLGQIK +F DKTGTLT+N+M+F+  +I G NY  E   DL     S+ E+
Sbjct:   38 DNKIKTTKYTIWSFIPKNLFEQFHRFANIYFLFIVGLNWVPAINAFGKEIAMLPLIFVLAVTAVKDLFEDRRRYNSDKKVNNTICQVYSSASASYIATKWKDVVVGDIIKLSSNEIIPADILLLNSSDENNICYVETANLDGETNLKQREVVNGLFKEDERFSPRNFNFKLKCETPNNHIYRFHGAIELDDSHTLAVGKE-------NLLLRGCIVRNTKNVEGVVVYAGHDTKAMLNNSGPRSKHSKVERDLNLDVIACVVILFTLCFLGGLGCGIW------TQNNDFFNAHFAPGGESSAPMEGFIRFWTFIIILQVLIPYSLYVSAELVKLGQVFLISSDLQLYHEETDQPVICRALNINEDLGQIKYVFSDKTGTLTENKMVFKKCTIGGVNYPHESAQDLPDAGPSDTED 440          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKREN--NEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVP 3269
            + SPDE ALV+     GF+ + RT   +II NA  ++  VYEIL  L F+S RK MSVIV+    G+I L CKGAD+V+F ++  N       +  T   +  +A  GLRTL +    L+  EY +W +   +   +L N  +++ E  +LIE NL L+GA  +EDKLQE VPE +    +A I IW+LTGDK+ETAI+I Y+ RL +    +              +  IRE + + L    R     E+ C        +D   L  +  +DELK  FL +A  C  V+CCR +P+QK +VV LVK + +   TLAIGDGANDV MIQ A +G+G+SG+EG QA  ASD+AI +F+YL +L+ VHG  SY +LA++ L  FYKN+ + ++  ++ + +GFS     D+    I+++I T +PP+  G++D+  S E +L  P++Y T  N+++Y  + FW  I+ S++ SL++F +P
Sbjct:  474 AASPDEGALVKGAKKLGFSFNVRTPTSVII-NAMGKE-EVYEILNVLEFNSTRKRMSVIVR-TPEGKIKLYCKGADTVVFERMRENQ----LYLETTVKHLEEFAKEGLRTLCIAMSELDPEEYSEWSKIYYQASTSLENRADKVDEAAELIERNLFLLGATAIEDKLQEGVPESIAALADADIKIWVLTGDKQETAINIGYACRLLTGEMKL-------LMCNDETLDGIREWLNEHLRMIGRNGIKCERMC-----CFFVDQVLLQAL--TDELKLNFLDLALCCKAVICCRVSPLQKSQVVRLVKHHVKDSITLAIGDGANDVGMIQAAHVGVGISGQEGLQAASASDYAIAQFRYLNKLLFVHGAWSYQRLAKLILYSFYKNVCLYVIELWFAMENGFSGQILFDKWCIGIYNVIFTSVPPLAIGLFDRTVSSESMLKYPKLYKTSQNAEIYNTKVFWLWIMTSVYHSLLLFYLP 931          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNR--PVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYF----EVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGF-IQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNN----------PHIL--------------QLLLLSAICNTTIIAKSNQREKKLVH 1571
            NN+I T KY F  F+   L EQF RYSN+FF+F  +L  I  V    + T  +P+L +L  + IK+ +ED +R+ +D  VNNR   VLR D  L       W ++ VGD++K+ +    PADL++  SS+P GMC++ET ++DGET LK R +  SL      + ++  + Y     E E  N ++Y F G I     GK    L+   ++LR   LRNT  V G+V Y G+ +K+  N+  A  KRS ++   N+ +L   G+L+ + + + IG  FY+          ++        ++  Q + + F T II++ ++IPI+L +TLE+VK  Q + I  D+ +Y    D     +  N+ E+LGQ+K +F DKTGTLT N M FR  +I G +Y+       +     N+ L NN          P +L              + L L ++C+T +  +  Q   K+++
Sbjct:   15 NNKISTAKYNFLTFLPKFLLEQFSRYSNVFFLFIALLQQIDGVSPTGRYTTAVPLLLVLSCSAIKEIIEDYKRHAADGLVNNRRVKVLR-DNTLQSLL---WIEVQVGDIVKVVNGHFFPADLILLSSSEPMGMCYVETSNLDGETNLKIRQMFNSLSLFIDCISKISGHCYLQGRVECEGPNNRLYDFVGNI--ALTGKKPVPLSADQVLLRGAQLRNTQWVFGLVAYTGHDSKLMQNSTAAPIKRSNVDHTTNIQILFLFGLLMALALCSTIG--FYVWAGEHEHAHWYLGYE-----ELPPQNYGLTFLTFIILYNNLIPISLTVTLEVVKFIQAIFINLDIDMYYAPSDTPAMARTSNLNEELGQVKYIFSDKTGTLTRNVMEFRKVTIGGISYRLSVRPFFVL--QNNDHLKNNSCGEGQSFSDPALLDNLREHHPTASVIREFLTLLSVCHTVVPERDTQNPDKIIY 472          

Query: 1809 LTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDI-------EKSLFDSKRENN--------EKTCK----------HKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKY----LKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTI----LDSLWQSLVIFAV 3266
            + N E   +  ++SPDE ALV      GF   +R+   L I    + +   +E+L  L F++ RK MSVIV+ N   +I L CKGADS+++ ++  +      ++++T  D+  +A+ GLRTLV+  + +   +Y+ W+    K    + N E +++ +Y+ IE NL L+GA  +EDKLQ+ VP+ +     A I IW+LTGDK ETA++I YS +L + + T      E      + M  +RE I       +  L D    NN         +T K          +  F LVI G SL V   + +L+ EFL +A  C  V+CCR TP+QK  VV LVK   +  TLAIGDGANDV+MI+ A IG+G+SG+EG QATLASD++  +F+Y    + RL+LVHG  SY ++ +     FYKN   +L+  +Y   +G+S     D      ++++ T  P +   ++D+D + E  +  P++Y+ G  + M+  R F  ++    L SLW   + + V
Sbjct:  472 IDNAEEGLVYQAQSPDEAALVTAARNFGFVFKERSPTTLTIVAMGQEE--QHELLAILDFNNDRKRMSVIVRQN--DKIKLYCKGADSIIYERLHPSCT---SLMDKTTEDLNKFAAEGLRTLVLAYKDITPQDYQAWKSKYDKACVAMDNREEQVQAVYEEIEKNLILIGATAIEDKLQDGVPDAIATLAAANIKIWVLTGDKPETAVNIGYSCQLLTDDMT------EVFMINGDSMDAVRESINMYKSKVQAGLDDKAAHNNSVSFRKGSRETAKSDSGGKTDGGNAGFGLVITGKSL-VFALNKQLELEFLELACMCKAVICCRVTPLQKALVVQLVKDNKKAVTLAIGDGANDVSMIKAAHIGVGISGQEGMQATLASDYSFAQFRYPLHSIVRLLLVHGRWSYMRMCKFLNYFFYKNFAFTLIQLWYAFFTGYSAQTLYDAWFISFYNVLFTSGPVVFLAIFDQDVNHENCIRYPKLYVPGQQNIMFNKRVFAYSLFYGSLTSLWLYFLAYGV 976          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKML--NEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYY---FEVEASNKQIYKFNGKI-FDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLC--CDSENEELHNNPH 1487
            +N IRT+KY    F+  NLFEQF+R +N++F+  VI+  IPE+ A    +  +P++F++  T IKD  +D+RR+ SDR+VNNR      K L  N     KW  I  GD++K+ + E+IPAD LI  +S+ +G+C+IET ++DGET LK R  +   D N    +E     +      E  N  + KFNGKI FD++       L+  NLILR  +LRNT+ V G V+YAG  +K+ MN+  + FKR+ L+  LN  ++    +L  +CI+  IG + +     +   V     NF  + +V   G   + + I+V  ++IPI+LYI++E+++  Q + I  D  +Y E  D     +   +TE+LGQI+ +F DKTGTLT N M F+  SI GK Y  E   L  C    S   +  +NP+
Sbjct:   25 DNFIRTSKYTIITFLPKNLFEQFQRVANMYFLLQVIIMSIPEITALKPESTAVPLVFVIGFTAIKDAYDDIRRHQSDRDVNNRK----SKALIGNSREEIKWMKIKCGDVLKIDNNEQIPADFLILSTSEENGLCYIETAELDGETNLKCRQPLP--DTNEMGDDEALLAKFKGTVHCEPPNNILDKFNGKIAFDNQ----EYSLDNDNLILRGCVLRNTDWVYGTVVYAGQDSKLMMNSGVSTFKRTNLDRLLNKLIIGIAVLLACICIVLSIGTTIWEELVGQNFQVFLQWPNF-YMNNVVFIGTCHWPSFIMVLNTLIPISLYISVEVIRMGQSIWINWDQYMYYEKKDTPARARTTTLTEELGQIEYIFSDKTGTLTQNVMTFKKCSIHGKMYG-EHAPLLYCIVLQSPLVDFSSNPY 434          

Query: 1842 SESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIRE----DIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWN------------TEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRG 3527
            + SPDE ALV   +  G     +  + + +    +     Y +L  L FDS RK MSVIVK  A G+  +  KGA++ +  ++  +  KD      T   +  YA  GLRTL + +R+    EY+  +  L+K    + + E ++ E+++ +E NL L+GA  +EDKLQ  VPE +E  +EAGI +W+LTGDK++TA++I++S   F                 +++M   R     + E+ L   K++   +    K F L++DG SL  I      KE F+ +  FC  V+CCR +P+QK +VV LVK   E   TLAIGDGAND  MIQ A +GIGV GKEG QA + SD+AI++F++L R++LVHGH  Y + A +    FYKN+      F Y   + FS            +++  T LP +IFG++++    +IL   P +Y     +       F   +    W +LV F    L +                + +  FG    +  VI     + + + +W+     +  G++ + F+L   + NS      D  + + Y+V     + G
Sbjct:  496 ASSPDEKALVEAAVRFGIVYRGKVGEDMEV--QMQGTSHRYTLLHVLEFDSTRKRMSVIVK-TAEGQYLMLTKGAETAILDRL-ESGPKDV-----TADHVDGYAEQGLRTLAVAQRVFTPEEYRDVDAKLTKAGQAINDREQQLAEVFEEVECNLHLLGATAVEDKLQAGVPETIEAMREAGIKVWVLTGDKEQTAVNISHSCGHFKHG--------------MDLMFVTRRSSPSECEQELLQFKQKVQSQ--PDKLFGLIVDGMSLVHIFNGH--KELFIEVCKFCMAVLCCRMSPLQKAQVVQLVKVSKEKPVTLAIGDGANDCGMIQEAHVGIGVMGKEGRQAVMTSDYAISRFRFLARVLLVHGHWYYIRSAILVQYFFYKNVCFITPQFIYAFFNAFSGQPLYHGFLLTCYNIFFTSLPILIFGIFNQHIGGDILQGRPSLYQDVAKNSRLSWVQFIYWVASGYWHALVFFFGGYLMFQGDLFDLLKPISILQNVGIWSFGTFVFAVCVIVSNLKLALVTHYWTWLTHVVTWGSI-LTFFLFAIVFNSFQTTFGDQVSIDMYQVFFTLFNEG 1046          

Query:  192 NIYPSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPV-LRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMK--SLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKI-FDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIV-CIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENE 1466
            N YPSN       + +  +N I T+KY  +NFI  NLFEQF+R +N +F+    +    +V   +   +++          +  G ED  R+  D+ VN+RP  + +D ++ +    + KDI VGD++++   E  P DL++  S DP G C I T ++DGET LK R  +   +  ++   L  +      E +  +  +Y ++G+I F+      +  L   NL+LR   L+N++ V G+ +Y G +TK+ +N  +A  K S +E  +N  +++ L +L++   I TG+    Y +         +   +    +   ++ F+ F   +I++  +IPI+LY+T+EL K    L    D+ +Y+   D+       ++ E+LGQ++ +F DKTGTLT+N+M F+  SI GK YK  EN++ LC D   +
Sbjct:   12 NRYPSNDPDVAIKQKRYADNMIVTSKYTIWNFIPKNLFEQFRRIANFYFLCIGTI----QVRGGSLIKSVVAGTDFYHTKCVAKGYEDYLRHKVDKEVNSRPCGVVFDGIVKDI---QSKDIKVGDIVRVKDNEEFPCDLIVLASDDPEGKCHITTANLDGETNLKVRSAVSRTAFLHSPEKLSSL--QATIECQHPHVDLYGYSGRIIFNANGENEITSLGPQNLLLRGARLKNSDHVFGVAVYTGKETKMALNQAEAPHKFSTVEKTMNTFLIVFLLVLVLQGAICTGLK---YWKESTVPGKAPYANDSGIASFKGVIEDFLVF---LILYNYVIPISLYVTVELQKFIGALFFAWDVKMYNPDTDEPAIANTSDLNEELGQVEYVFTDKTGTLTENDMQFKECSINGKKYK--ENEMELCVDGPGQ 424          

Query: 2778 TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSL-----CYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLG--IGFYLELFILNS 3455
            TLAIGDGAND  MIQ A +GIGV GKEG QA + SD+AI++F++L R++LVHGH  Y + A +    FYKN+      F Y   + FS            +++  T LP +IFG++++    +IL   P +Y     +       F   +    W +LV F    L      + +  + +  FG    +  VI     + + + +W+   W   + T G  + F+L   + NS
Sbjct:   20 TLAIGDGANDCGMIQEAHVGIGVMGKEGRQAVMTSDYAISRFRFLARVLLVHGHWYYIRSAILVQYFFYKNVCFITPQFIYAFFNAFSGQPLYHGFLLTCYNIFFTSLPILIFGIFEQHIGGDILQGRPSLYQDVAKNSRLSWVQFIYWVASGYWHALVFFFGGYLMFQGDLFGSINVGIWSFGTFVFAVCVIVSNLKLALVTHYWT---WLTHVVTWGSILTFFLFAIVFNS 249          

Query:  201 PSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYD-VYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY--KTEENDL---------------RLCCDSENEELHNNP---HILQLLLLSA---ICNTTIIAKSNQREKKLVHVDSCSTSLTNVT-STGGKIQSFFDYGVXXXXXXXXXXXXXDTD----PIPK---DLIK------AVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELS--PLILS-------ESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETV-KXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            P+ F+ P         N I+T KY    FI +NL+EQF R +N++F+   ILNFIP V AF    A+IPI  I+ +T +KDG ED RRY SD+ +NN P L Y +    +   +WKD+ VGD +K+   E +PADLL+ ++SDP+ +C IET ++DGET LKQR  +  L  ++   E    N     E  N  +  F  K F  +  K        +L+LR   +RNT    G V+YAG++TK  +NN   R+KRS LE +LNVD+  C+ +L I+C++  +G   +L+  + + +  F+ S+     D   L  F  F+T II+ Q +IPI+LY+++ELVK  QI  I  D+ LYDE  D ++  ++ NITEDLGQI+ +F DKTGTLT+N+M+FR  SI GK+Y  K    DL               ++     N  L   P   H +   +L +   +    +IA  + +E +++  +     ++    S+ G    + D+ ++L I   + +S+  T      +PK    L+K       VF+  +   S +S  K +  A+    R L    LS  P   S       ESPDE ALV      GF L  RT + + +      + +V+E+L TL FDS RK MSV+V+   TGE  L  KGAD  +  +++    +  +I   T+  +  YA +GLRTL + K+I++  EY+ W     +    +   E  +      +E+ L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK ETA++I Y+ RL  + + V    S   +   ++++    E++ +   D +  N + T   ++  L+IDG +L++ L+ D L++ FL +A  C  V+CCR TP+QK  VV LV+   +V TLA+GDGANDVNMIQ AD+GIG+SG+EG QA +ASDFAIT+FK+LK+L+LVHGH  + +LA M +  FYKN     ++F+YQ   GFS +  ID    + F+L  T  PPI+FG+ DKD S E+L+  P++Y TG  S  Y  R FW ++LD+ +QSLV F VP L Y  +++ +  FG    +  +  +  H+ IE + W+V HW I +G++ + F + L   +++CV    CN   NPY +L   M+    YLI  +ST ++L PR
Sbjct:   42 PNRFFKP---------NAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIYSRTAKHYIERRWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQRNALPGLCTSNDVFEPESFNCTVVCEKPNNNLNHF--KCFVEKPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLWLKNLSDVPS--FLVSDSKGHLDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDYPHKENGKDLSHFIHTFKNAVTQFQKVILYYRNIALCRKPTPKHNVSTSMLDSGDGVLGVVVIAFLHHQETQVIPDEKLLQQISRSERSSSGISDPYMDFFLALAICNSVVVSMATTQRQRVSLPKYFSVLVKRTGSFWKVFDSPKQNGSSTSAHKRSDDANGVQPRALDTVTLSARPAAASGDVCYEAESPDEAALVYAAKTYGFTLLARTPNSVTV-RVPSGEELVFEVLDTLAFDSNRKRMSVLVRHPITGEYVLYTKGADYAIM-ELLGTPGQQKKIAADTQYHLDCYAKDGLRTLCITKKIVSSREYQSWLADRKRALAAIDGREELMMASAVQLETELTLLGATGIEDRLQESVPDTITALREAGIKVWVLTGDKPETALNIGYACRLMEEGDLVINMTSVVFQVTCVSILDCTLEEVRRYHEDPR--NVDTT---QKISLMIDGDTLAIALSPD-LQDRFLDLAKRCRSVLCCRVTPLQKSRVVKLVRDKLKVMTLAVGDGANDVNMIQVADVGIGISGQEGMQAVMASDFAITRFKHLKKLLLVHGHWCHTRLANMIIYFFYKNAAYVNLLFWYQFYCGFSGTAMIDYWLMIFFNLFFTSTPPIMFGIMDKDVSAEMLMGVPELYRTGQGSGEYNFRTFWISMLDAFYQSLVCFFVPYLAYQGSDVDIFTFGTPLNTSSLFIILLHLGIEIKSWTVVHWIIMLGSVALYFIVTL-AYSAICVT---CNPPSNPYWILQNQMADPMFYLICIISTVVALLPR 1191          

Query:  201 PSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYD-VYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEEN--DLRLCCDSENEEL---------HNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVT-STGGKIQSFFDYGVXXXXXXXXXXXXXDTD---------PIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELS--PLILS-------ESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKI---IANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCN-TDNPYKVLHYTMSRGKTYLIIALSTAISLFPR 3578
            P+ F+ P         N I+T KY    FI +NL+EQF R +N++F+   ILNFIP V AF    A+IPI  I+ +T +KDG ED RRY SD+ +NN P L Y K   E    +WKD+ VGD +K+   E +PADLL+ ++SDP+ +C IET ++DGET LKQR       NN     E F N     E  N  +  F  K F  +  K        +L+LR   +RNT    G V+YAG++TK  +NN   R+KRS LE +LNVD+  C+ +L I+C++  +G   +L+  + + +  F+ S+     D   L  F  F+T II+ Q +IPI+LY+++ELVK  QI  I  D+ LYDE  D ++  ++ NITEDLGQI+ +F DKTGTLT+N+M+FR  SI GK+Y  +EN  DL     +    +         + N + +    L  +    +IA  + +E +++  +     ++    S+ G    + D+ ++L I   + +S+  T          PI    +   F   ++  S S++ +S+  A+    R L    LS  P   S       ESPDE ALV      GF L  RT + + +      + +V+E+L TL FDS RK MSV+V+   TGE  L  KGAD  +   +    A   +  +I   T+  +  YA +GLRTL   + I     Y + E  ++                   +E+ L L+GA G+ED+LQE VP+ +   +EAGI +W+LTGDK ETA++I Y+ RL  + + V           ++++    E++ +   D +  N + T   ++  L+IDG +L++ L+ D L++ FL +A  C  V+CCR TP+QK  VV LV+   +V TLA+GDGANDVNMIQ AD+GIG+SG+EG QA +ASDFAIT+FK+LK+L+LVHGH  + +LA M +  FYKN     ++F+YQ   GFS +  ID    + F+L  T  PPI+FG+ DKD S E+L+  P++Y TG  S  Y  R FW ++LD+ +QSLV F VP L Y  +++ +  FG    +  +  +  H+ IE + W+V HW I +G++ + F + L   +++CV    CN   NPY +L   M+    YLI  +ST ++L PR
Sbjct:   54 PNRFFKP---------NAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIYTKHYIER---RWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQR-------NNDVFEPESF-NCTVVCEKPNNNLNHF--KCFVEKPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLWLKNLSDVPS--FLVSDSKGHLDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDYPHKENGKDLSHFIHTFKNAVTQFQKVILYYRNSNRVICCCLRKLSPLVVIAFLHHQETQVIPDEKLLQQISRSERSSSGISDPYMDFFLALAICNSVVVSMATTQRQRVIHLHTPIRLTTLWRAFLPKQNGSSTSAHKRSD-DANGVQPRALDTVTLSARPAAASGDVCYEAESPDEAALVYAAKTYGFTLLARTPNSVTV-RVPSGEELVFEVLDTLAFDSNRKRMSVLVRHPITGEYVLYTKGADYAIMELLGTPYAGDGQQKKIAADTQYHLDCYAKDGLRTL-SEQHISFIWAYGREELMMASAVQ---------------LETELTLLGATGIEDRLQESVPDTITALREAGIKVWVLTGDKPETALNIGYACRLMEEGDLV---------TCVSILDCTLEEVRRYHEDPR--NVDTT---QKISLMIDGDTLAIALSPD-LQDRFLDLAKRCRSVLCCRVTPLQKSRVVKLVRDKLKVMTLAVGDGANDVNMIQVADVGIGISGQEGMQAVMASDFAITRFKHLKKLLLVHGHWCHTRLANMIIYFFYKNAAYVNLLFWYQFYCGFSGTAMIDYWLMIFFNLFFTSTPPIMFGIMDKDVSAEMLMGVPELYRTGQGSGEYNFRTFWISMLDAFYQSLVCFFVPYLAYQGSDVDIFTFGTPLNTSSLFIILLHLGIEIKSWTVVHWIIMLGSVALYFIVTL-AYSAICVT---CNPPSNPYWILQNQMADPMFYLICIISTVVALLPR 1153          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGK--IFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNA---FKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHK----------EFVLVIDGCSLSVILTSDE-------LKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEI-SMGE------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFP----RLLIKGFLMESRDSVFYEAHRRINKLGIRKWTT-NVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDK 3779
            +NRI ++KY F+NFI  NLFEQF+R +N +F+   ++  I +    +  T+ +P+ F++ VT IK G ED  R+ +D ++N  PV   ++   +    +   + VGD++ +   E  P DL++  SS   G CF+ T  +DGE++ K  + +       T  E    +   E E     +YKF G+  I+  +    V+ L   NL+LR   L+NT  +  + +Y G +TK+ +N +    KRS +E  +N  +++ L ILI   ++  +    +    ++ +      +       V ++ F  F   +++F  IIP+++Y+T+E+ K      I  D  ++DE + +   V   ++ E+LGQ++ +F DKTGTLT+N M F                   CC   N  +   PH        AICN  I+              S ++S+  + S+ G  +  ++                       DL         ++Q      K   T ++   R +   + +   +S SPDE ALV  +   G+   +   + + I N     +R    +E+L  L FDS+R+ MSVIV+ +++GE  L CKGADS +FP +++        + Q KA +   A  GLRTL +  R L+E+EY +    L++ +  L + E  + + YD+IE    L+GA  +ED+LQE   + +E   +AG+ +W+LTGDK ETA +  Y+++LF ++  + E            +++ R + E+SL D   + N    + +          +F L+IDG +LS +L  ++        +E FL I   C+ V+CCR  P+QK ++V L+K   E   TLAIGDGANDV+MI  A +GIG+ GKEG QA   SD+AI KFK+LK+++LVHGH  Y ++A +    FYKN+      F YQ   GFS     D     ++++  T LP +++ + ++  + E L   P +Y     + + R   F       ++ +++ F      + NT   S G+      FG +  + +V  +   + +++ HW+  +  +  G+L    +  +F L    ++    N    Y V    +S G  +L I L   +SL P    ++L +     + ++   + H  +   G+ +W+T +   + K        ++S+  LG  E+   L+ D+
Sbjct:   47 DNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLVIFLIQLIIDTPT-SPITSGLPLFFVITVTAIKQGYEDWLRHKADCSLNECPVDVVEQ--GKVVRTQSHKLRVGDIVMVREDETFPCDLILLSSSRYDGTCFVTTTSLDGESSHKTYYAVPDTMAFRTEQEVDSLHATIECEQPQPDLYKFVGRVDIYKDKQEPVVRTLGAENLLLRGATLKNTGHIYAVAVYTGMETKMALNYQSKSQKRSAVEKSMNAFLVVYLCILISKAVINTVLKYAWQWSPDRDEPWYNHRTEIERQRHVVIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFIAWDEEMFDEELGQGAQVNTSDLNEELGQVEYVFTDKTGTLTENNMEFIE-----------------CCVDGNVYI---PH--------AICNGQIL--------------SAASSIDMIDSSPGGYRREYE-----------------------DLFFRALCLCHTVQV-----KEEETVESI-KRGIHQGKSTSFYISSSPDEVALVEGMKRLGYTYLRLKDNYMEILNKDDEIER----FELLHVLNFDSVRRRMSVIVR-SSSGEYLLFCKGADSSIFPLVVSGK------VEQVKARVEQNAVEGLRTLCVAYRRLSESEYLEASHRLTEAKIALQDREQRLAQTYDIIEREFVLLGATAVEDRLQEKAADTIESLHKAGMKVWVLTGDKMETAAATCYASKLFRRSTQILE------------LTKKRTE-EQSLHDVLFDLNRTVLRQRSISGLSVDCLDFGLIIDGATLSGVLKPNQDSAGHGNYREIFLEICRNCSAVLCCRMAPLQKAQIVKLIKSSKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAIPKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLVEQHVTMETLKREPSLYRDIAKNALLRWPAFLYWTCLGVFDAVIFFFGAYFLFDNTTFTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHHWTWINHFVIWGSL---LFYVIFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLITVSLLPDVIKKVLCRAVCPTASENA--QNHDELFPDGVAEWSTLSFGRSCKGT----STESSRLNLGAAEKLPVLRSDR 1152          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGK--IFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNA---FKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHK----------EFVLVIDGCSLSVILTSDE-------LKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEI-SMGE------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIK 3590
            +NRI ++KY F+NFI  NLFEQF+R +N +F+   ++  I +    +  T+ +P+ F++ VT IK G ED  R+ +D ++N  PV   ++   +    +   + VGD++ +   E  P DL++  SS   G CF+ T  +DGE++ K  + +       T  E    +   E E     +YKF G+  I+  +    V+ L   NL+LR   L+NT  +  + +Y G +TK+ +N +    KRS +E  +N  +++ L ILI   ++  +    +    ++ +      +       V ++ F  F   +++F  IIP+++Y+T+E+ K      I  D  ++DE + +   V   ++ E+LGQ++ +F DKTGTLT+N M F                   CC   N  +   PH        AICN  I+              S ++S+  + S+ G  +  ++                       DL         ++Q      K   T ++   R +   + +   +S SPDE ALV  +   G+   +   + + I N     +R    +E+L  L FDS+R+ MSVIV+ +++GE  L CKGADS +FP +++        + Q KA +   A  GLRTL +  R L+E+EY +    L++ +  L + E  + + YD+IE    L+GA  +ED+LQE   + +E   +AG+ +W+LTGDK ETA +  Y+++LF ++  + E            +++ R + E+SL D   + N    + +          +F L+IDG +LS +L  ++        +E FL I   C+ V+CCR  P+QK ++V L+K   E   TLAIGDGANDV+MI  A +GIG+ GKEG QA   SD+AI KFK+LK+++LVHGH  Y ++A +    FYKN+      F YQ   GFS     D     ++++  T LP +++ + ++  + E L   P +Y     + + R   F       ++ +++ F      + NT   S G+      FG +  + +V  +   + +++ HW+  +  +  G+L   FY+ +F L    ++    N    Y V    +S G  +L I L   +SL P ++ K
Sbjct:   47 DNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLVIFLIQLIIDTPT-SPITSGLPLFFVITVTAIKQGYEDWLRHKADCSLNECPVDVVEQ--GKVVRTQSHKLRVGDIVMVREDETFPCDLILLSSSRYDGTCFVTTTSLDGESSHKTYYAVPDTMAFRTEQEVDSLHATIECEQPQPDLYKFVGRVDIYKDKQEPVVRTLGAENLLLRGATLKNTGHIYAVAVYTGMETKMALNYQSKSQKRSAVEKSMNAFLVVYLCILISKAVINTVLKYAWQWSPDRDEPWYNHRTEIERQRHVVIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFIAWDEEMFDEELGQGAQVNTSDLNEELGQVEYVFTDKTGTLTENNMEFIE-----------------CCVDGNVYI---PH--------AICNGQIL--------------SAASSIDMIDSSPGGYRREYE-----------------------DLFFRALCLCHTVQV-----KEEETVESI-KRGIHQGKSTSFYISSSPDEVALVEGMKRLGYTYLRLKDNYMEILNKDDEIER----FELLHVLNFDSVRRRMSVIVR-SSSGEYLLFCKGADSSIFPLVVSGK------VEQVKARVEQNAVEGLRTLCVAYRRLSESEYLEASHRLTEAKIALQDREQRLAQTYDIIEREFVLLGATAVEDRLQEKAADTIESLHKAGMKVWVLTGDKMETAAATCYASKLFRRSTQILE------------LTKKRTE-EQSLHDVLFDLNRTVLRQRSISGLSVDCLDFGLIIDGATLSGVLKPNQDSAGHGNYREIFLEICRNCSAVLCCRMAPLQKAQIVKLIKSSKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAIPKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLVEQHVTMETLKREPSLYRDIAKNALLRWPAFLYWTCLGVFDAVIFFFGAYFLFDNTTFTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHHWTWINHFVIWGSL--LFYV-IFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLITVSLLPDVIKK 1090          

Query:  246 NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGK--IFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNA---FKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHK------------EFVLVIDGCSLSVILTSDE-------LKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXR-TLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEI-SMGE------FGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFL-----MESRDSVFYEAHRRINKLGI 3659
            +NRI ++KY F+NFI  NLFEQF+R +N +F+   ++  I +    +  T+ +P+ F++ VT IK G ED  R+ +D ++N  PV   ++   +    +   + VGD++ +   E  P DL++  SS   G CF+ T  +DGE++ K  + +       T  E    +   E E     +YKF G+  I+  +    V+ L   NL+LR   L+NT  +  + +Y G +TK+ +N +    KRS +E  +N  +++ L ILI   ++  +    +    ++ +      +       V ++ F  F   +++F  IIP+++Y+T+E+ K      I  D  ++DE + +   V   ++ E+LGQ++ +F DKTGTLT+N M F                   CC   N  +   PH        AICN  I++ ++  +     +DS         S GG  +  F   + L     +                   ++ E+++S+               R +   + +   +S SPDE ALV  +   G+   +   + + I N     +R    +E+L  L FDS+R+ MSVIV+ +++GE  L CKGADS +FP +++        + Q KA +   A  GLRTL +  R L+E+EY +    L++ +  L + E  + + YD+IE    L+GA  +ED+LQE   + +E   +AG+ +W+LTGDK ETA +  Y+++LF ++  + E            +++ R + E+SL D   + N    + +            +F L+IDG +LS +L  ++        +E FL I   C+ V+CCR  P+QK ++V L+K   E   TLAIGDGANDV+MI  A +GIG+ GKEG QA   SD+AI KFK+LK+++LVHGH  Y ++A +    FYKN+      F YQ   GFS     D     ++++  T LP +++ + ++  + E L   P +Y     + + R   F       ++ +++ F      + NT   S G+      FG +  + +V  +   + +++ HW+  +  +  G+L    +  +F L    ++    N    Y V    +S G  +L I L   +SL P ++ K          S ++    +HRR  K+G+
Sbjct:   53 DNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLVIFLIQLIIDTPT-SPITSGLPLFFVITVTAIKQGYEDWLRHKADCSLNECPVDVVEQ--GKVVRTQSHKLRVGDIVMVREDETFPCDLILLSSSRYDGTCFVTTTSLDGESSHKTYYAVPDTMAFRTEQEVDSLHATIECEQPQPDLYKFVGRVDIYKDKQEPVVRTLGAENLLLRGATLKNTGHIYAVAVYTGMETKMALNYQSKSQKRSAVEKSMNAFLVVYLCILISKAVINTVLKYAWQWSPDRDEPWYNHRTEIERQRHVVIRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFIAWDEEMFDEELGQGAQVNTSDLNEELGQVEYVFTDKTGTLTENNMEFIE-----------------CCVDGNVYI---PH--------AICNGQILSAASSIDM----IDS---------SPGGYRRDLFFRALCLCHTVQV-------------------KEEETVESIK--------------RGIHQGKSTSFYISSSPDEVALVEGMKRLGYTYLRLKDNYMEILNKDDEIER----FELLHVLNFDSVRRRMSVIVR-SSSGEYLLFCKGADSSIFPLVVSGK------VEQVKARVEQNAVEGLRTLCVAYRRLSESEYLEASHRLTEAKIALQDREQRLAQTYDIIEREFVLLGATAVEDRLQEKAADTIESLHKAGMKVWVLTGDKMETAAATCYASKLFRRSTQILE------------LTKKRTE-EQSLHDVLFDLNRTVLRQRSISGYGLSLDCLDFGLIIDGATLSGVLKPNQDSAGHGNYREIFLEICRNCSAVLCCRMAPLQKAQIVKLIKSSKEHPITLAIGDGANDVSMILEAHVGIGIMGKEGRQAARNSDYAIPKFKHLKKMLLVHGHYYYIRIAELVQYFFYKNVCFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLVEQHVTMETLKREPSLYRDIAKNALLRWPAFLYWTCLGVFDAVIFFFGAYFLFDNTTFTSNGQMFGNWTFGTLVFTVLVFTVTLKLALDTHHWTWINHFVIWGSL---LFYVIFSLLWGGIIWPFLNYQRMYYVFMQMLSSGPAWLSIILLITVSLLPDVIKKVLCRAVCPTASENAQVRSSHRR--KVGL 1121          

Query:  147 MTDCCKISKIHDENVNIYPSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL 3866
            MTDCCKISKIHDENVNIYPSNFYIPLTDESKK+NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNN TNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCD+ENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVSLPIEPILPISIEDTDPIPKDLIKAVFEKAESLQSV+SYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVEDNLINNE+EIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLF+SKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL
Sbjct:    1 MTDCCKISKIHDENVNIYPSNFYIPLTDESKKLNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNLTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDNENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVSLPIEPILPISIEDTDPIPKDLIKAVFEKAESLQSVNSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVEDNLINNESEIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLFNSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL 1240          

Query:  147 MTDCCKISKIHDENVNIYPSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLIKAVFEKAESLQSVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKR------------------------ILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL 3866
            MTDCCKISKIHDENVNIYPSNFYIPLTDESKK+NNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNN TNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCD+ENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVSLPIEPILPISIEDTDPIPKDLIKAVFEKAESLQSV+SYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKR                        ILNENEYKKWEETLSKVEDNLINNE+EIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLF+SKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL
Sbjct:    1 MTDCCKISKIHDENVNIYPSNFYIPLTDESKKLNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNLTNLEEVFKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDNENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLVHVDSCSTSLTNVTSTGGKIQSFFDYGVSLPIEPILPISIEDTDPIPKDLIKAVFEKAESLQSVNSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRVSNLHKINVFNAIIEGKSNNNIIWILNENEYKKWEETLSKVEDNLINNESEIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLFNSKRENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKKLKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL 1264          

Query:  801 KIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSEN--------EELHNNPHILQLLLLS---------AICNTTIIAKSNQREKKLVHV---------DSCSTSLTNV-----TSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLI----------KAVFEKAESLQ---SVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEK--SLFDSKRENNEKTCKHK----EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRK 3665
            K+F+    KS+  L  +NLILR  ILRNT  V GIVIYAGN+TK  +NN Q  FKRS LE Q+N D++ C+GILII+CI   IG   +++ F+ +  V+F + +   + ++ LQGFI FWT +I+FQ+IIP+ LY+T+ELVK HQ+ HIT DL LYD+ +DK+  V+A NITEDLGQI+ +FCDKTGTLT+N M F+ A+I   ++  +  +  L  DS+         ++ H N  I + L +S         A+CNTT+++++    K +V +         +S  ++ TN      TSTG  + S F      P  P   I+I++T  IPK+L           K+V  +   +Q   S+S   + N+     P++   ++ L     SESPDE AL +     G  L QR    + IW  + +K    + L   PFDS RK MSVI+ D  TG I+L CKGAD+V+ P I  N+ +  ++I++   ++  Y+ NGLRTL++ KR L+E ++ +W      VE NL  +E E+  LY  +E ++ L+GA G+ED+LQE VPE LE  ++AGINIW+LTGDK ETAI+IAYS +LF++N+ +        +   N    + ++IEK       ++  N  T K+     E+ L+++G ++SVIL  D + + FL +A  C  VVCCR TP +K  +V +VK   +VRTLAIGDGANDVNMIQTA +GIG+ GKEG QA +ASDFAITKFKYL+RL+LVHGH  YD+LARMSL MFYK+ II LV F++Q+L+GFS S  IDQ++Q++F+L  TGLPP+I G+WDKDF   +L  NPQIY +GI+ K YRPRDFWR I+DS+WQSLVIF +  LCY  TE+SM EFGI+  + ++I  ++++++ESR WSVFHW  C+G+L + ++ E+F+LNSLCVV++DCNTDNPYKV+++TM + KTYL++ L TAI+LFPR+++K  L+ SR S+ YEA RR+  L  R+
Sbjct:   46 KVFEDN-AKSIT-LKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNENLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDMSIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNL-SVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGSLIQKSSSISKLNRYNVNQGKCPYK---DDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCIFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSR--QMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEI-------FTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQ 1035          

Query:  801 KIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDSEN--------EELHNNPHILQLLLLS---------AICNTTIIAKSNQREKKLVHV---------DSCSTSLTNV-----TSTGGKIQSFFDYGVXXXXXXXXXXXXXDTDPIPKDLI----------KAVFEKAESLQ---SVSSYPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEK--SLFDSKRENNEKTCKHK----EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRK 3665
            K+F+    KS+  L  +NLILR  ILRNT  V GIVIYAGN+TK  +NN Q  FKRS LE Q+N D++ C+GILII+CI   IG   +++ F+ +  V+F + +   + ++ LQGFI FWT +I+FQ+IIP+ LY+T+ELVK HQ+ HIT DL LYD+ +DK+  V+A NITEDLGQI+ +FCDKTGTLT+N M F+ A+I   ++  +  +  L  DS+         ++ H N  I + L +S         A+CNTT+++++    K +V +         +S  ++ TN      TSTG  + S F      P  P   I+I++T  IPK+L           K+V  +   +Q   S+S   + N+     P++   ++ L     SESPDE AL +     G  L QR    + IW  + +K    + L   PFDS RK MSVI+ D  TG I+L CKGAD+V+ P I  N+ +  ++I++   ++  Y+ NGLRTL++ KR L+E ++ +W      VE NL  +E E+  LY  +E ++ L+GA G+ED+LQE VPE LE  ++AGINIW+LTGDK ETAI+IAYS +LF++N+ +        +   N    + ++IEK       ++  N  T K+     E+ L+++G ++SVIL  D + + FL +A  C  VVCCR TP +K  +V +VK   +VRTLAIGDGANDVNMIQTA +GIG+ GKEG QA +ASDFAITKFKYL+RL+LVHGH  YD+LARMSL MFYK+ II LV F++Q+L+GFS S  IDQ++Q++F+L  TGLPP+I G+WDKDF   +L  NPQIY +GI+ K YRPRDFWR I+DS+WQSLVIF +  LCY  TE+SM EFGI+  + ++I  ++++++ESR WSVFHW  C+G+L + ++ E+F+LNSLCVV++DCNTDNPYKV+++TM + KTYL++ L TAI+LFPR+++K  L+ SR S+ YEA RR+  L  R+
Sbjct:   20 KVFEDN-AKSIT-LKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNENLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDMSIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNL-SVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGSLIQKSSSISKLNRYNVNQGKCPYK---DDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCIFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSR--QMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEI-------FTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQ 1009          

Query: 1809 LTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQ--TKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVXXXXXXXXXXXXXXYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKXXXXXXXXXXXNVMSQIREDIEKSLFDSK----RENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGXXXXXXXXXXXXRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLL--------DCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNL 3749
            +++++L     SESPDE ALV+    +G+ L QR  + + IWN    + + Y +L+ LPFDS RK MS+IVK   T  I + CKGADS MF     N  KD   I+Q  TK  + AYA  GLR LVMG+R+++++ + +W +   + E  L NNE E+  L   IES++ L+G  G+ED LQ+ V + +E  + AGI +WILTGDK+ETAI+IAYS +LFS+N+ + E+S  S+ +  +++ +   +I KS + ++    R+   +    K+  L +DG +L+  +  DE+K +FLH+A  C  VVC R TPIQK E+V LVK+   ++TLAIGDGANDV+MIQ AD+GIG+ G EG QA +ASDFA+TKFKYLKRL+LVHG   Y+KLAR +L MFYK+ I  L+MF++Q  + FS S  ID +TQ++F++  TGLPPII+G+WDKD   + L+ NP++Y  GIN K Y+P  FW  ILD++WQS VI+ +  + + +++I + EFG I  +C +I    H+ IE+R W+ FH        G+G ++  FIL  L   ++         C +D+PY  +   M R   +L+  ++   ++FPRL I         ++ Y+      KLG        +    ++P + D +N    +G++
Sbjct:  694 ISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF----GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNI-KSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAM-EDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGIGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGIWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFH--------GLGIFIS-FILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIPEEKLG-----KGSNLYFDYEPELVDVRNPSTIIGSV 1334          

Query:  195 IYPSNFYIPLTDESKKVNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNSTNLEEVFKNYYFEVEASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFY-LRGFNK--IQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDS-------------------------------------ENEELHNNPHILQLLLLSAICNTTIIAKSNQREKKLV 1568
            IYPS       ++ K  NN +RT KY    FI +NLFEQF R++N++F+F +ILNF+PE+ AF +  A IP++F+L VT IKD VED RR+ +D+ VN+   L Y     +F   KW     GD IKL + E IPAD+++ +S+D SG+C IET ++DGE+ LKQR V+  ++NN+T   E+  N + EVE  N++IYKFNG IF     IG +++     NL+LR   LRNT EV GIV+YAG +TK  +NN   RFKRS LE Q+N D++ C+ +LII+C+   IG   + +  F +  I+   F  S  TVI +  +Q F+ FWT +I +Q++IP+ LY+T E VK HQ+ HI  DL +YD   +K ++V+A+NI EDLGQI+ +FCDKTGTLT+N M F+ A I G +Y  ++++     D                                      + EE+    ++    LL  ICNTT+++  N+ EK  V
Sbjct:   17 IYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFIKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVM-MENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRK---NNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVLLLIILCLSCSIGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS-LNKNEKHPV 511