Ankyrin-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012522 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 39
Homology
BLAST of Ankyrin-2 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]) HSP 1 Score: 805.053 bits (2078), Expect = 0.000e+0 Identity = 402/775 (51.87%), Postives = 562/775 (72.52%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D+N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH++A+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL
Sbjct: 44 SYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-NLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815 HSP 2 Score: 431.409 bits (1108), Expect = 1.734e-122 Identity = 208/501 (41.52%), Postives = 307/501 (61.28%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDE 4317
W + LD+V L+ P+ +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E + RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + +++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP + + DE
Sbjct: 965 WAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKETESDQDDE 1450
BLAST of Ankyrin-2 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 803.127 bits (2073), Expect = 0.000e+0 Identity = 420/803 (52.30%), Postives = 570/803 (70.98%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ I + N NGLNA+HLAAKEG+ +VQ L+ G SVD AT+KGNT+LHIASLAG+ EVV +L++ ANIN +SQNGFTPLYMAAQENH+DVVK LLE GANQ+ T+DGFTPLAVALQQG+++ V ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+KLL+ + +++ TRDGL+P+HCAARSG + ++ +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS T ++ E ALH+AAR Q E + LL + A +ARARE QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ +++ +LLE TKKGFTPLH+A+KYG + VA+ LLL + +S G +GLTPLHVA +Y++ ++ LLL+ A+ + KNGYTPLH+ AKKN +++ L++ GA N +++G TPLHL S G+ +++ LLLD A+++ ++GLT+LHLAA++++ ++ + L K AD T++GYT L A H+G ++ V LL++ +VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 13 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN-GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAK-LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE 812 HSP 2 Score: 455.292 bits (1170), Expect = 9.063e-132 Identity = 245/613 (39.97%), Postives = 365/613 (59.54%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAEN-------IQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIF--NPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W E LD+V L P+ +GFL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ T+P + + E LA R+I + S GP+++EIPH AALR ERE+VVL+S+NG SWKEH +T+ + + L + E + + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ + L++K GN SPIVTLEPRRRKFH+ IT+T+P+P S + +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V AS +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL + +++D + PCG+++FM++P+ T+ L + IC L+ITLP T++ ++ ++E D+ NP D++ER+ E + +A +G W +L L +E+I +I +++ + +D+++ L W+ +D + + N +E L I R DIV
Sbjct: 920 WGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEGGSFLVLVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKS---------------TRGLVHQAICNLNITLPIY-TKESESDQEQEEEIDMTSEKNPQDEQERI-------EERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWL--ERDGKHATDTNLVE-CLTKINRMDIV 1506
BLAST of Ankyrin-2 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]) HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0 Identity = 408/801 (50.94%), Postives = 570/801 (71.16%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D+N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH++A+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL
Sbjct: 1 MSEEPKEKNAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-NLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 798 HSP 2 Score: 434.876 bits (1117), Expect = 9.140e-125 Identity = 231/614 (37.62%), Postives = 353/614 (57.49%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNID--EEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ P+ +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E + RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + +++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITL P K + D + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 966 WAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITL---PAHKKIEKTDRRQSFASLALRKRYSYLTEPGMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1555
BLAST of Ankyrin-2 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0 Identity = 420/803 (52.30%), Postives = 570/803 (70.98%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ I + N NGLNA+HLAAKEG+ +VQ L+ G SVD AT+KGNT+LHIASLAG+ EVV +L++ ANIN +SQNGFTPLYMAAQENH+DVVK LLE GANQ+ T+DGFTPLAVALQQG+++ V ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+KLL+ + +++ TRDGL+P+HCAARSG + ++ +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS T ++ E ALH+AAR Q E + LL + A +ARARE QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ +++ +LLE TKKGFTPLH+A+KYG + VA+ LLL + +S G +GLTPLHVA +Y++ ++ LLL+ A+ + KNGYTPLH+ AKKN +++ L++ GA N +++G TPLHL S G+ +++ LLLD A+++ ++GLT+LHLAA++++ ++ + L K AD T++GYT L A H+G ++ V LL++ +VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 13 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN-GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAK-LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE 812 HSP 2 Score: 461.07 bits (1185), Expect = 7.986e-134 Identity = 245/606 (40.43%), Postives = 365/606 (60.23%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIF--NPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W E LD+V L P+ +GFL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ T+P + + E LA R+I + S GP+++EIPH AALR ERE+VVL+S+NG SWKEH +T+ + + L + E + + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ + L++K GN SPIVTLEPRRRKFH+ IT+T+P+P S + +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V AS +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL + +++D + PCG+++FM++P+ T+ L + IC L+ITLP T++ ++ ++E D+ NP D++ER+ E + +A +G W +L L +E+I +I +++ + +D+++ L W+ +D + + N +E L I R DIV
Sbjct: 920 WGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKS---------------TRGLVHQAICNLNITLPIY-TKESESDQEQEEEIDMTSEKNPQDEQERI-------EERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWL--ERDGKHATDTNLVE-CLTKINRMDIV 1499
BLAST of Ankyrin-2 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0 Identity = 420/803 (52.30%), Postives = 570/803 (70.98%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ I + N NGLNA+HLAAKEG+ +VQ L+ G SVD AT+KGNT+LHIASLAG+ EVV +L++ ANIN +SQNGFTPLYMAAQENH+DVVK LLE GANQ+ T+DGFTPLAVALQQG+++ V ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+KLL+ + +++ TRDGL+P+HCAARSG + ++ +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS T ++ E ALH+AAR Q E + LL + A +ARARE QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ +++ +LLE TKKGFTPLH+A+KYG + VA+ LLL + +S G +GLTPLHVA +Y++ ++ LLL+ A+ + KNGYTPLH+ AKKN +++ L++ GA N +++G TPLHL S G+ +++ LLLD A+++ ++GLT+LHLAA++++ ++ + L K AD T++GYT L A H+G ++ V LL++ +VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 13 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN-GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAK-LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE 812 HSP 2 Score: 451.825 bits (1161), Expect = 1.107e-130 Identity = 245/618 (39.64%), Postives = 365/618 (59.06%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAG------------FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIF--NPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W E LD+V L P+ +G FL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ T+P + + E LA R+I + S GP+++EIPH AALR ERE+VVL+S+NG SWKEH +T+ + + L + E + + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ + L++K GN SPIVTLEPRRRKFH+ IT+T+P+P S + +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V AS +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL + +++D + PCG+++FM++P+ T+ L + IC L+ITLP T++ ++ ++E D+ NP D++ER+ E + +A +G W +L L +E+I +I +++ + +D+++ L W+ +D + + N +E L I R DIV
Sbjct: 920 WGTENLDNVALSSSPIHSGRASPCLERDNSSFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKS---------------TRGLVHQAICNLNITLPIY-TKESESDQEQEEEIDMTSEKNPQDEQERI-------EERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWL--ERDGKHATDTNLVE-CLTKINRMDIV 1511
BLAST of Ankyrin-2 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 828.935 bits (2140), Expect = 0.000e+0 Identity = 425/779 (54.56%), Postives = 568/779 (72.91%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
E + +FLRAAR+G++EKV E L+A + SNANGLN++HLA+KEG+ EVV+ LI+ VD ATRKGNT+LHIASLAG+ +V++L+E+ AN+NV+S NGFTPLYMAAQENH +VVK LL++GANQA++T+DGFTPLAVALQQG+D+VV +LL+NDS+ KVRLPALHIAAKKDD AA+LL+ ++ N D S SGFTPLHIAAHY + NV +LL+EK A+VN+ A++NI+PLHVA KWG+ M LL+S+ A ++S T+D L+P+HCAARSG + ++ +L+ GA I K+KNGL L MA QGD + +TL+ VD VT+DYLT LHVAAHCG++ A++LL + + N+RALNGFTPLHIACKK + K+VELL+KY+A I +TTE+GLTPLH+AAFMG+ IV LL+ GA+ T++ E LHLAAR NQ + ++L+ + A +A+ARE QTPLHIA R+GN IV LL AGA+ N T+DNY+ LHIAAKEG+ E++ +LL+H TKKGFTPLH+ASKYG ++V R LLL + G + +TPLHVA +YN+ ++ LLL+ A+ KNGYTPLH+ AKKN +E+ L+ A+ NA+S+ GFTPLHL++ G+KEI LL++ +DV +A NGLTA+HL A+++ + + L A+I++KT GYT LH A HFGQ+ VK L++ DV +T T LH AAQQGH VR LL+N N Q G T L +AQ+ Y+++ ETL
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLL-QNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN-GAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVR-LLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 434.491 bits (1116), Expect = 4.236e-125 Identity = 243/619 (39.26%), Postives = 358/619 (57.84%), Query Frame = 1
Query: 2836 DSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS----SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIK---DLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP--------TKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIH 4641
D+V + + FLISF+VDA+GG M+ RH +RI VP P R+ C RK+ P L + E LA RI+ + + GP++LE+PH A+LR ERE+V+L+SD+G WKEH T+ AVQ+ L AE++ + RI RI+T+ P YF++++R++Q++ +G EGG + SSV +VQA+FP+G+L K IK+S+Q + + ++ + GN VA+SPIVT+EPRRRKFH+ ITL +PLP ++ Y+ Q +LRLLCSI+G + P WEDITGT+ LT VSFTTT+SAR WL+DC + ++A +Y E+ +P++ +F VF RR E Q+R C+TDD +KTLE QE+F+LI+ VEVL+ +LE SGN++PIT S +QLSL PFQENRL+F + + D G++ FM +P+I S + L PQ+PICTL I+LP P +K L ++ + + L D E + + ++K +G DW +L L + +I I +E K L +WI K + +N N L+ +LR IGR+DIV++ +
Sbjct: 989 DNVPIGHHVTQPSFLISFLVDARGGAMRGCRHSGVRIIVPPRKASQPIRVTCRYLRKDKLAHPPPLSEGEELASRILEMAPAGAKFLGPVILEVPHFASLRDREREIVILRSDDGQHWKEHQLEATEDAVQEVLNESFDAEDLAQLDDLQTPRITRILTSDFPMYFAVVTRVRQEVHCVGPEGGVIISSVVPRVQAIFPDGSLTKTIKVSVQAQPVPQEMVTRLHGNRVAVSPIVTVEPRRRKFHKPITLCIPLPQSNNRGMLTQYSGQQGQEPPTLRLLCSITGGSAPAQWEDITGTTQLTFTGDEVSFTTTVSARFWLMDCQTPRDAARMAQEVYNEAISIPYMAKFAVFARRTFPVEGQLRVFCMTDDKEDKTLEKQEHFKLIAKSRDVEVLKGKHQFLEFSGNLVPITKSGDQLSLFFLPFQENRLAFMVKTRSNDDNEAATEGRIGFMAEPKIRSDA-------------LPPQQPICTLAISLPEYTGEIKTAPPPKKDLTPFEQRYGSAL---EKDLPEFVHQNVLKG----------IGADWPRLGRALEVPHRDIQHIRQNYPGQECKN--TLKIWIHLKK--EDANQDN-LDQALRQIGRDDIVRSIAY 1576 HSP 3 Score: 311.227 bits (796), Expect = 2.199e-85 Identity = 202/604 (33.44%), Postives = 315/604 (52.15%), Query Frame = 2
Query: 782 LIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMS 2506
L+ D+N N + LH+A+K G E+++ LI ++A V++ TR G + +H A+ +G I+ IL+ENGA++ +S NG T L MA Q + EV K L+ G + T D T ALH+AA + AA +LL+N N + + +GFTPLHIA + +LL++ A++N ++PLH+A G + N+LL GA I T LH AAR+ ++ +L++ A +A+ + PLH+A + + LL A + VT D T LH+AA G +++LLL+ P+++ GFTPLHIA K R++V +LLL + + GLTPLHVA + ++ LL AN + G TPLHL A+ N +V ++LI GA V+AQ+++ TPLH+ S GN +I+ LLL A A+ N + + LH+AA++ + ++ LL AD + T+ G+T LH A +G ++ V++LL++ V+ + T LH+AA + + LLL+N K G T L +A K++ + IA TL + P S
Sbjct: 52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQ-GAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVV-ELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS 653 HSP 4 Score: 126.716 bits (317), Expect = 1.064e-28 Identity = 89/300 (29.67%), Postives = 150/300 (50.00%), Query Frame = 2
Query: 1574 QLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q + A A P + + AA+ G E LL + G LH+ASK G +V R+ L+ + ++ G T LH+A+ ++ +L++ ANVN NG+TPL++ A++N EV K L+ GAN ++ GFTPL + G+ ++ +LL+ ++ + + L ALH+AA+K+ T LL+ E + ++ G+T LH A H+G ++LL+K +VN Q + LH+A + G + LLL ++ + K LT L A + + + + L
Sbjct: 18 QEVQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRE-LIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS----KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLL 312
BLAST of Ankyrin-2 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 828.935 bits (2140), Expect = 0.000e+0 Identity = 425/779 (54.56%), Postives = 568/779 (72.91%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
E + +FLRAAR+G++EKV E L+A + SNANGLN++HLA+KEG+ EVV+ LI+ VD ATRKGNT+LHIASLAG+ +V++L+E+ AN+NV+S NGFTPLYMAAQENH +VVK LL++GANQA++T+DGFTPLAVALQQG+D+VV +LL+NDS+ KVRLPALHIAAKKDD AA+LL+ ++ N D S SGFTPLHIAAHY + NV +LL+EK A+VN+ A++NI+PLHVA KWG+ M LL+S+ A ++S T+D L+P+HCAARSG + ++ +L+ GA I K+KNGL L MA QGD + +TL+ VD VT+DYLT LHVAAHCG++ A++LL + + N+RALNGFTPLHIACKK + K+VELL+KY+A I +TTE+GLTPLH+AAFMG+ IV LL+ GA+ T++ E LHLAAR NQ + ++L+ + A +A+ARE QTPLHIA R+GN IV LL AGA+ N T+DNY+ LHIAAKEG+ E++ +LL+H TKKGFTPLH+ASKYG ++V R LLL + G + +TPLHVA +YN+ ++ LLL+ A+ KNGYTPLH+ AKKN +E+ L+ A+ NA+S+ GFTPLHL++ G+KEI LL++ +DV +A NGLTA+HL A+++ + + L A+I++KT GYT LH A HFGQ+ VK L++ DV +T T LH AAQQGH VR LL+N N Q G T L +AQ+ Y+++ ETL
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLL-QNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN-GAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVR-LLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 434.491 bits (1116), Expect = 4.236e-125 Identity = 243/619 (39.26%), Postives = 358/619 (57.84%), Query Frame = 1
Query: 2836 DSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS----SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIK---DLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP--------TKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIH 4641
D+V + + FLISF+VDA+GG M+ RH +RI VP P R+ C RK+ P L + E LA RI+ + + GP++LE+PH A+LR ERE+V+L+SD+G WKEH T+ AVQ+ L AE++ + RI RI+T+ P YF++++R++Q++ +G EGG + SSV +VQA+FP+G+L K IK+S+Q + + ++ + GN VA+SPIVT+EPRRRKFH+ ITL +PLP ++ Y+ Q +LRLLCSI+G + P WEDITGT+ LT VSFTTT+SAR WL+DC + ++A +Y E+ +P++ +F VF RR E Q+R C+TDD +KTLE QE+F+LI+ VEVL+ +LE SGN++PIT S +QLSL PFQENRL+F + + D G++ FM +P+I S + L PQ+PICTL I+LP P +K L ++ + + L D E + + ++K +G DW +L L + +I I +E K L +WI K + +N N L+ +LR IGR+DIV++ +
Sbjct: 989 DNVPIGHHVTQPSFLISFLVDARGGAMRGCRHSGVRIIVPPRKASQPIRVTCRYLRKDKLAHPPPLSEGEELASRILEMAPAGAKFLGPVILEVPHFASLRDREREIVILRSDDGQHWKEHQLEATEDAVQEVLNESFDAEDLAQLDDLQTPRITRILTSDFPMYFAVVTRVRQEVHCVGPEGGVIISSVVPRVQAIFPDGSLTKTIKVSVQAQPVPQEMVTRLHGNRVAVSPIVTVEPRRRKFHKPITLCIPLPQSNNRGMLTQYSGQQGQEPPTLRLLCSITGGSAPAQWEDITGTTQLTFTGDEVSFTTTVSARFWLMDCQTPRDAARMAQEVYNEAISIPYMAKFAVFARRTFPVEGQLRVFCMTDDKEDKTLEKQEHFKLIAKSRDVEVLKGKHQFLEFSGNLVPITKSGDQLSLFFLPFQENRLAFMVKTRSNDDNEAATEGRIGFMAEPKIRSDA-------------LPPQQPICTLAISLPEYTGEIKTAPPPKKDLTPFEQRYGSAL---EKDLPEFVHQNVLKG----------IGADWPRLGRALEVPHRDIQHIRQNYPGQECKN--TLKIWIHLKK--EDANQDN-LDQALRQIGRDDIVRSIAY 1576 HSP 3 Score: 311.227 bits (796), Expect = 2.199e-85 Identity = 202/604 (33.44%), Postives = 315/604 (52.15%), Query Frame = 2
Query: 782 LIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMS 2506
L+ D+N N + LH+A+K G E+++ LI ++A V++ TR G + +H A+ +G I+ IL+ENGA++ +S NG T L MA Q + EV K L+ G + T D T ALH+AA + AA +LL+N N + + +GFTPLHIA + +LL++ A++N ++PLH+A G + N+LL GA I T LH AAR+ ++ +L++ A +A+ + PLH+A + + LL A + VT D T LH+AA G +++LLL+ P+++ GFTPLHIA K R++V +LLL + + GLTPLHVA + ++ LL AN + G TPLHL A+ N +V ++LI GA V+AQ+++ TPLH+ S GN +I+ LLL A A+ N + + LH+AA++ + ++ LL AD + T+ G+T LH A +G ++ V++LL++ V+ + T LH+AA + + LLL+N K G T L +A K++ + IA TL + P S
Sbjct: 52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQ-GAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVV-ELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS 653 HSP 4 Score: 126.716 bits (317), Expect = 1.064e-28 Identity = 89/300 (29.67%), Postives = 150/300 (50.00%), Query Frame = 2
Query: 1574 QLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q + A A P + + AA+ G E LL + G LH+ASK G +V R+ L+ + ++ G T LH+A+ ++ +L++ ANVN NG+TPL++ A++N EV K L+ GAN ++ GFTPL + G+ ++ +LL+ ++ + + L ALH+AA+K+ T LL+ E + ++ G+T LH A H+G ++LL+K +VN Q + LH+A + G + LLL ++ + K LT L A + + + + L
Sbjct: 18 QEVQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRE-LIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS----KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLL 312
BLAST of Ankyrin-2 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 828.55 bits (2139), Expect = 0.000e+0 Identity = 425/779 (54.56%), Postives = 568/779 (72.91%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
E + +FLRAAR+G++EKV E L+A + SNANGLN++HLA+KEG+ EVV+ LI+ VD ATRKGNT+LHIASLAG+ +V++L+E+ AN+NV+S NGFTPLYMAAQENH +VVK LL++GANQA++T+DGFTPLAVALQQG+D+VV +LL+NDS+ KVRLPALHIAAKKDD AA+LL+ ++ N D S SGFTPLHIAAHY + NV +LL+EK A+VN+ A++NI+PLHVA KWG+ M LL+S+ A ++S T+D L+P+HCAARSG + ++ +L+ GA I K+KNGL L MA QGD + +TL+ VD VT+DYLT LHVAAHCG++ A++LL + + N+RALNGFTPLHIACKK + K+VELL+KY+A I +TTE+GLTPLH+AAFMG+ IV LL+ GA+ T++ E LHLAAR NQ + ++L+ + A +A+ARE QTPLHIA R+GN IV LL AGA+ N T+DNY+ LHIAAKEG+ E++ +LL+H TKKGFTPLH+ASKYG ++V R LLL + G + +TPLHVA +YN+ ++ LLL+ A+ KNGYTPLH+ AKKN +E+ L+ A+ NA+S+ GFTPLHL++ G+KEI LL++ +DV +A NGLTA+HL A+++ + + L A+I++KT GYT LH A HFGQ+ VK L++ DV +T T LH AAQQGH VR LL+N N Q G T L +AQ+ Y+++ ETL
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLL-QNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN-GAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVR-LLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 434.491 bits (1116), Expect = 4.529e-125 Identity = 243/619 (39.26%), Postives = 358/619 (57.84%), Query Frame = 1
Query: 2836 DSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS----SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIK---DLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP--------TKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIH 4641
D+V + + FLISF+VDA+GG M+ RH +RI VP P R+ C RK+ P L + E LA RI+ + + GP++LE+PH A+LR ERE+V+L+SD+G WKEH T+ AVQ+ L AE++ + RI RI+T+ P YF++++R++Q++ +G EGG + SSV +VQA+FP+G+L K IK+S+Q + + ++ + GN VA+SPIVT+EPRRRKFH+ ITL +PLP ++ Y+ Q +LRLLCSI+G + P WEDITGT+ LT VSFTTT+SAR WL+DC + ++A +Y E+ +P++ +F VF RR E Q+R C+TDD +KTLE QE+F+LI+ VEVL+ +LE SGN++PIT S +QLSL PFQENRL+F + + D G++ FM +P+I S + L PQ+PICTL I+LP P +K L ++ + + L D E + + ++K +G DW +L L + +I I +E K L +WI K + +N N L+ +LR IGR+DIV++ +
Sbjct: 989 DNVPIGHHVTQPSFLISFLVDARGGAMRGCRHSGVRIIVPPRKASQPIRVTCRYLRKDKLAHPPPLSEGEELASRILEMAPAGAKFLGPVILEVPHFASLRDREREIVILRSDDGQHWKEHQLEATEDAVQEVLNESFDAEDLAQLDDLQTPRITRILTSDFPMYFAVVTRVRQEVHCVGPEGGVIISSVVPRVQAIFPDGSLTKTIKVSVQAQPVPQEMVTRLHGNRVAVSPIVTVEPRRRKFHKPITLCIPLPQSNNRGMLTQYSGQQGQEPPTLRLLCSITGGSAPAQWEDITGTTQLTFTGDEVSFTTTVSARFWLMDCQTPRDAARMAQEVYNEAISIPYMAKFAVFARRTFPVEGQLRVFCMTDDKEDKTLEKQEHFKLIAKSRDVEVLKGKHQFLEFSGNLVPITKSGDQLSLFFLPFQENRLAFMVKTRSNDDNEAATEGRIGFMAEPKIRSDA-------------LPPQQPICTLAISLPEYTGEIKTAPPPKKDLTPFEQRYGSAL---EKDLPEFVHQNVLKG----------IGADWPRLGRALEVPHRDIQHIRQNYPGQECKN--TLKIWIHLKK--EDANQDN-LDQALRQIGRDDIVRSIAY 1576 HSP 3 Score: 310.842 bits (795), Expect = 2.789e-85 Identity = 202/604 (33.44%), Postives = 315/604 (52.15%), Query Frame = 2
Query: 782 LIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMS 2506
L+ D+N N + LH+A+K G E+++ LI ++A V++ TR G + +H A+ +G I+ IL+ENGA++ +S NG T L MA Q + EV K L+ G + T D T ALH+AA + AA +LL+N N + + +GFTPLHIA + +LL++ A++N ++PLH+A G + N+LL GA I T LH AAR+ ++ +L++ A +A+ + PLH+A + + LL A + VT D T LH+AA G +++LLL+ P+++ GFTPLHIA K R++V +LLL + + GLTPLHVA + ++ LL AN + G TPLHL A+ N +V ++LI GA V+AQ+++ TPLH+ S GN +I+ LLL A A+ N + + LH+AA++ + ++ LL AD + T+ G+T LH A +G ++ V++LL++ V+ + T LH+AA + + LLL+N K G T L +A K++ + IA TL + P S
Sbjct: 52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQ-GAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVV-ELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS 653 HSP 4 Score: 126.331 bits (316), Expect = 1.215e-28 Identity = 89/300 (29.67%), Postives = 150/300 (50.00%), Query Frame = 2
Query: 1574 QLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q + A A P + + AA+ G E LL + G LH+ASK G +V R+ L+ + ++ G T LH+A+ ++ +L++ ANVN NG+TPL++ A++N EV K L+ GAN ++ GFTPL + G+ ++ +LL+ ++ + + L ALH+AA+K+ T LL+ E + ++ G+T LH A H+G ++LL+K +VN Q + LH+A + G + LLL ++ + K LT L A + + + + L
Sbjct: 18 QEVQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRE-LIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS----KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLL 312
BLAST of Ankyrin-2 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 828.55 bits (2139), Expect = 0.000e+0 Identity = 425/779 (54.56%), Postives = 568/779 (72.91%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
E + +FLRAAR+G++EKV E L+A + SNANGLN++HLA+KEG+ EVV+ LI+ VD ATRKGNT+LHIASLAG+ +V++L+E+ AN+NV+S NGFTPLYMAAQENH +VVK LL++GANQA++T+DGFTPLAVALQQG+D+VV +LL+NDS+ KVRLPALHIAAKKDD AA+LL+ ++ N D S SGFTPLHIAAHY + NV +LL+EK A+VN+ A++NI+PLHVA KWG+ M LL+S+ A ++S T+D L+P+HCAARSG + ++ +L+ GA I K+KNGL L MA QGD + +TL+ VD VT+DYLT LHVAAHCG++ A++LL + + N+RALNGFTPLHIACKK + K+VELL+KY+A I +TTE+GLTPLH+AAFMG+ IV LL+ GA+ T++ E LHLAAR NQ + ++L+ + A +A+ARE QTPLHIA R+GN IV LL AGA+ N T+DNY+ LHIAAKEG+ E++ +LL+H TKKGFTPLH+ASKYG ++V R LLL + G + +TPLHVA +YN+ ++ LLL+ A+ KNGYTPLH+ AKKN +E+ L+ A+ NA+S+ GFTPLHL++ G+KEI LL++ +DV +A NGLTA+HL A+++ + + L A+I++KT GYT LH A HFGQ+ VK L++ DV +T T LH AAQQGH VR LL+N N Q G T L +AQ+ Y+++ ETL
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLL-QNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN-GAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVR-LLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 434.491 bits (1116), Expect = 4.529e-125 Identity = 243/619 (39.26%), Postives = 358/619 (57.84%), Query Frame = 1
Query: 2836 DSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS----SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIK---DLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP--------TKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIH 4641
D+V + + FLISF+VDA+GG M+ RH +RI VP P R+ C RK+ P L + E LA RI+ + + GP++LE+PH A+LR ERE+V+L+SD+G WKEH T+ AVQ+ L AE++ + RI RI+T+ P YF++++R++Q++ +G EGG + SSV +VQA+FP+G+L K IK+S+Q + + ++ + GN VA+SPIVT+EPRRRKFH+ ITL +PLP ++ Y+ Q +LRLLCSI+G + P WEDITGT+ LT VSFTTT+SAR WL+DC + ++A +Y E+ +P++ +F VF RR E Q+R C+TDD +KTLE QE+F+LI+ VEVL+ +LE SGN++PIT S +QLSL PFQENRL+F + + D G++ FM +P+I S + L PQ+PICTL I+LP P +K L ++ + + L D E + + ++K +G DW +L L + +I I +E K L +WI K + +N N L+ +LR IGR+DIV++ +
Sbjct: 989 DNVPIGHHVTQPSFLISFLVDARGGAMRGCRHSGVRIIVPPRKASQPIRVTCRYLRKDKLAHPPPLSEGEELASRILEMAPAGAKFLGPVILEVPHFASLRDREREIVILRSDDGQHWKEHQLEATEDAVQEVLNESFDAEDLAQLDDLQTPRITRILTSDFPMYFAVVTRVRQEVHCVGPEGGVIISSVVPRVQAIFPDGSLTKTIKVSVQAQPVPQEMVTRLHGNRVAVSPIVTVEPRRRKFHKPITLCIPLPQSNNRGMLTQYSGQQGQEPPTLRLLCSITGGSAPAQWEDITGTTQLTFTGDEVSFTTTVSARFWLMDCQTPRDAARMAQEVYNEAISIPYMAKFAVFARRTFPVEGQLRVFCMTDDKEDKTLEKQEHFKLIAKSRDVEVLKGKHQFLEFSGNLVPITKSGDQLSLFFLPFQENRLAFMVKTRSNDDNEAATEGRIGFMAEPKIRSDA-------------LPPQQPICTLAISLPEYTGEIKTAPPPKKDLTPFEQRYGSAL---EKDLPEFVHQNVLKG----------IGADWPRLGRALEVPHRDIQHIRQNYPGQECKN--TLKIWIHLKK--EDANQDN-LDQALRQIGRDDIVRSIAY 1576 HSP 3 Score: 310.842 bits (795), Expect = 2.789e-85 Identity = 202/604 (33.44%), Postives = 315/604 (52.15%), Query Frame = 2
Query: 782 LIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMS 2506
L+ D+N N + LH+A+K G E+++ LI ++A V++ TR G + +H A+ +G I+ IL+ENGA++ +S NG T L MA Q + EV K L+ G + T D T ALH+AA + AA +LL+N N + + +GFTPLHIA + +LL++ A++N ++PLH+A G + N+LL GA I T LH AAR+ ++ +L++ A +A+ + PLH+A + + LL A + VT D T LH+AA G +++LLL+ P+++ GFTPLHIA K R++V +LLL + + GLTPLHVA + ++ LL AN + G TPLHL A+ N +V ++LI GA V+AQ+++ TPLH+ S GN +I+ LLL A A+ N + + LH+AA++ + ++ LL AD + T+ G+T LH A +G ++ V++LL++ V+ + T LH+AA + + LLL+N K G T L +A K++ + IA TL + P S
Sbjct: 52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQ-GAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVV-ELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS 653 HSP 4 Score: 126.331 bits (316), Expect = 1.215e-28 Identity = 89/300 (29.67%), Postives = 150/300 (50.00%), Query Frame = 2
Query: 1574 QLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q + A A P + + AA+ G E LL + G LH+ASK G +V R+ L+ + ++ G T LH+A+ ++ +L++ ANVN NG+TPL++ A++N EV K L+ GAN ++ GFTPL + G+ ++ +LL+ ++ + + L ALH+AA+K+ T LL+ E + ++ G+T LH A H+G ++LL+K +VN Q + LH+A + G + LLL ++ + K LT L A + + + + L
Sbjct: 18 QEVQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRE-LIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS----KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLL 312
BLAST of Ankyrin-2 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 827.395 bits (2136), Expect = 0.000e+0 Identity = 425/779 (54.56%), Postives = 568/779 (72.91%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
E + +FLRAAR+G++EKV E L+A + SNANGLN++HLA+KEG+ EVV+ LI+ VD ATRKGNT+LHIASLAG+ +V++L+E+ AN+NV+S NGFTPLYMAAQENH +VVK LL++GANQA++T+DGFTPLAVALQQG+D+VV +LL+NDS+ KVRLPALHIAAKKDD AA+LL+ ++ N D S SGFTPLHIAAHY + NV +LL+EK A+VN+ A++NI+PLHVA KWG+ M LL+S+ A ++S T+D L+P+HCAARSG + ++ +L+ GA I K+KNGL L MA QGD + +TL+ VD VT+DYLT LHVAAHCG++ A++LL + + N+RALNGFTPLHIACKK + K+VELL+KY+A I +TTE+GLTPLH+AAFMG+ IV LL+ GA+ T++ E LHLAAR NQ + ++L+ + A +A+ARE QTPLHIA R+GN IV LL AGA+ N T+DNY+ LHIAAKEG+ E++ +LL+H TKKGFTPLH+ASKYG ++V R LLL + G + +TPLHVA +YN+ ++ LLL+ A+ KNGYTPLH+ AKKN +E+ L+ A+ NA+S+ GFTPLHL++ G+KEI LL++ +DV +A NGLTA+HL A+++ + + L A+I++KT GYT LH A HFGQ+ VK L++ DV +T T LH AAQQGH VR LL+N N Q G T L +AQ+ Y+++ ETL
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLL-QNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN-GAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVR-LLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 2 Score: 433.335 bits (1113), Expect = 9.167e-125 Identity = 241/606 (39.77%), Postives = 353/606 (58.25%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS----SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIK---DLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP--------TKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIH 4641
FLISF+VDA+GG M+ RH +RI VP P R+ C RK+ P L + E LA RI+ + + GP++LE+PH A+LR ERE+V+L+SD+G WKEH T+ AVQ+ L AE++ + RI RI+T+ P YF++++R++Q++ +G EGG + SSV +VQA+FP+G+L K IK+S+Q + + ++ + GN VA+SPIVT+EPRRRKFH+ ITL +PLP ++ Y+ Q +LRLLCSI+G + P WEDITGT+ LT VSFTTT+SAR WL+DC + ++A +Y E+ +P++ +F VF RR E Q+R C+TDD +KTLE QE+F+LI+ VEVL+ +LE SGN++PIT S +QLSL PFQENRL+F + + D G++ FM +P+I S + L PQ+PICTL I+LP P +K L ++ + + L D E + + ++K +G DW +L L + +I I +E K L +WI K + +N N L+ +LR IGR+DIV++ +
Sbjct: 1008 FLISFLVDARGGAMRGCRHSGVRIIVPPRKASQPIRVTCRYLRKDKLAHPPPLSEGEELASRILEMAPAGAKFLGPVILEVPHFASLRDREREIVILRSDDGQHWKEHQLEATEDAVQEVLNESFDAEDLAQLDDLQTPRITRILTSDFPMYFAVVTRVRQEVHCVGPEGGVIISSVVPRVQAIFPDGSLTKTIKVSVQAQPVPQEMVTRLHGNRVAVSPIVTVEPRRRKFHKPITLCIPLPQSNNRGMLTQYSGQQGQEPPTLRLLCSITGGSAPAQWEDITGTTQLTFTGDEVSFTTTVSARFWLMDCQTPRDAARMAQEVYNEAISIPYMAKFAVFARRTFPVEGQLRVFCMTDDKEDKTLEKQEHFKLIAKSRDVEVLKGKHQFLEFSGNLVPITKSGDQLSLFFLPFQENRLAFMVKTRSNDDNEAATEGRIGFMAEPKIRSDA-------------LPPQQPICTLAISLPEYTGEIKTAPPPKKDLTPFEQRYGSAL---EKDLPEFVHQNVLKG----------IGADWPRLGRALEVPHRDIQHIRQNYPGQECKN--TLKIWIHLKK--EDANQDN-LDQALRQIGRDDIVRSIAY 1582 HSP 3 Score: 310.457 bits (794), Expect = 3.362e-85 Identity = 202/604 (33.44%), Postives = 315/604 (52.15%), Query Frame = 2
Query: 782 LIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMS 2506
L+ D+N N + LH+A+K G E+++ LI ++A V++ TR G + +H A+ +G I+ IL+ENGA++ +S NG T L MA Q + EV K L+ G + T D T ALH+AA + AA +LL+N N + + +GFTPLHIA + +LL++ A++N ++PLH+A G + N+LL GA I T LH AAR+ ++ +L++ A +A+ + PLH+A + + LL A + VT D T LH+AA G +++LLL+ P+++ GFTPLHIA K R++V +LLL + + GLTPLHVA + ++ LL AN + G TPLHL A+ N +V ++LI GA V+AQ+++ TPLH+ S GN +I+ LLL A A+ N + + LH+AA++ + ++ LL AD + T+ G+T LH A +G ++ V++LL++ V+ + T LH+AA + + LLL+N K G T L +A K++ + IA TL + P S
Sbjct: 52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQ-GAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVV-ELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS 653 HSP 4 Score: 126.331 bits (316), Expect = 1.351e-28 Identity = 89/300 (29.67%), Postives = 150/300 (50.00%), Query Frame = 2
Query: 1574 QLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q + A A P + + AA+ G E LL + G LH+ASK G +V R+ L+ + ++ G T LH+A+ ++ +L++ ANVN NG+TPL++ A++N EV K L+ GAN ++ GFTPL + G+ ++ +LL+ ++ + + L ALH+AA+K+ T LL+ E + ++ G+T LH A H+G ++LL+K +VN Q + LH+A + G + LLL ++ + K LT L A + + + + L
Sbjct: 18 QEVQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRE-LIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDS----KGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLL 312
BLAST of Ankyrin-2 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0334060) HSP 1 Score: 856.284 bits (2211), Expect = 0.000e+0 Identity = 443/804 (55.10%), Postives = 587/804 (73.01%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMM---SGSEEKKLILDQPEKM 2551
+FLRAAR+GN+E+V E L+ +I + SNANGLNA+HLA+K+G+ VV L+ G VD AT+KGNT+LHIASLAG+ EVV LLLE A++NV+SQNGFTPLYMAAQENH VV++LL GANQ++ T+DGFTPLAVA+QQG+DKVV +LL++D+R KVRLPALHIAAKKDDV AA+LL+ +D N D S SGFTPLHIA+HY N N+A LLI+K ADVN+ AK+NI+PLHVAAKWGK M+ LL+ + N+ + TRDGL+P+HCAARSG E ++ +LLE GA I K+KNGL L MA QG+ + + L+ VD VT+DYLTALHVAAHCG++ A++LL N + NARALNGFTPLHIACKK + K+VELL+++ A I++TTE+GLTPLH+AAFMG IV LL++ AS T++ E LHLAAR NQ + +ILL + A +ARARE QTPLHIA R+GN IV LL GA + TKD YTALHIAAKEG+ E++ +L+E+ DA TKKGFTPLH+ +KYG ++VA QLLL + + ++ G +G+TPLHVA +YN+ ++ LLL+ A+ + KNG+TPLH+ A+KN +++ L++ GA NA+S+ GFTPLHL+S G+ EI LL++ A VNH A+NGLT +HL A+++ ++ E L K A+I T+ GYT LH A HFGQ V+ LLQ +V+A T++G T LH AQQGH IV LLL+++ + N Q G T L +A+K Y+++ ++L +T E S +EEK ++ PE M
Sbjct: 164 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLL-DNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRN-GAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVA-QLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVV-APEAM 963 HSP 2 Score: 436.032 bits (1120), Expect = 2.550e-124 Identity = 234/600 (39.00%), Postives = 347/600 (57.83%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKS-----------ELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTC 4635
FL+SF+VDA+GG M+ RH +R+ +P S PTR+ C + + P L + EALA R++ L + GP+++E+PH A+LR ERE+++L+SDNG +W+EHT ++ + D L E I E Q N + R +T PQYF+++SR++Q++ IG EGG V+S+V QVQAVFP+GAL KKIK+ LQ + +L K G GVA+SPIVT+EPRRRKFH+AITL++P P Y+ T +LRLLCSI+G + WED+TG++PLT + CVSFTTT+SAR WL+DC ++ ++A+ LY+E VPFI +F+VF ++ E ++R C+TDD +KTLE E + ++ VEVLE ++E +GN++P+T S +QL ++ F+ENRL F R+KD G+ FM++P++ G P PQ+PIC L+I LP E D D+ RT + S ++ I +++ +G DW +L +G+ EEI I Q+ D I KD ++ + LE +L++IGR+DI+K C
Sbjct: 1078 FLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGNTPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAK---------GEP-----PQQPICILNIVLP------------EAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNT---DSIARQAQSMIRLYKDKPNYDILS-LETALKNIGRDDIMKKC 1647 HSP 3 Score: 309.686 bits (792), Expect = 2.090e-84 Identity = 221/685 (32.26%), Postives = 336/685 (49.05%), Query Frame = 2
Query: 710 HQSA-SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHI---------------------------------ACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLH--P------------------------------EANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
HQSA G T AA N+ ++ N D+N N + LH+A+K G ++ L+ + A V+S T+ G + +H A+ +G E ++ +LLE+ A + +S+NG T L MA Q + V + L++ G + T D T ALH+AA ++ AA +LL N+ N + + +GFTPLHI A K ++ MV LL++ +I + T GLTPLH AA G +++V++LL+ GA IS T LH+AA+ + +ILL H P A+ NARA TPLHIA + +VE LL GA + T+ T LH+AA G I LL+H PD T +G TPLH+A++ + + R +LL ++ TPLH+A+ + +++ LLL A V+ K+ YT LH+ AK+ EV +LI+ GA ++A ++KGFTPLHL + G+ ++ +LLL ADV+ Q +NG+T LH+A N + LL+ A + G+T LH A Q+ LL+ NA++ G T LHL++Q+GH I LL++++ VNH K GLT + + ++ +N+AE L K
Sbjct: 155 HQSAGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIR-ILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 838
BLAST of Ankyrin-2 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303117) HSP 1 Score: 856.284 bits (2211), Expect = 0.000e+0 Identity = 443/804 (55.10%), Postives = 587/804 (73.01%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMM---SGSEEKKLILDQPEKM 2551
+FLRAAR+GN+E+V E L+ +I + SNANGLNA+HLA+K+G+ VV L+ G VD AT+KGNT+LHIASLAG+ EVV LLLE A++NV+SQNGFTPLYMAAQENH VV++LL GANQ++ T+DGFTPLAVA+QQG+DKVV +LL++D+R KVRLPALHIAAKKDDV AA+LL+ +D N D S SGFTPLHIA+HY N N+A LLI+K ADVN+ AK+NI+PLHVAAKWGK M+ LL+ + N+ + TRDGL+P+HCAARSG E ++ +LLE GA I K+KNGL L MA QG+ + + L+ VD VT+DYLTALHVAAHCG++ A++LL N + NARALNGFTPLHIACKK + K+VELL+++ A I++TTE+GLTPLH+AAFMG IV LL++ AS T++ E LHLAAR NQ + +ILL + A +ARARE QTPLHIA R+GN IV LL GA + TKD YTALHIAAKEG+ E++ +L+E+ DA TKKGFTPLH+ +KYG ++VA QLLL + + ++ G +G+TPLHVA +YN+ ++ LLL+ A+ + KNG+TPLH+ A+KN +++ L++ GA NA+S+ GFTPLHL+S G+ EI LL++ A VNH A+NGLT +HL A+++ ++ E L K A+I T+ GYT LH A HFGQ V+ LLQ +V+A T++G T LH AQQGH IV LLL+++ + N Q G T L +A+K Y+++ ++L +T E S +EEK ++ PE M
Sbjct: 14 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLL-DNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRN-GAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVA-QLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVV-APEAM 813 HSP 2 Score: 436.417 bits (1121), Expect = 1.891e-124 Identity = 234/600 (39.00%), Postives = 347/600 (57.83%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKS-----------ELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTC 4635
FL+SF+VDA+GG M+ RH +R+ +P S PTR+ C + + P L + EALA R++ L + GP+++E+PH A+LR ERE+++L+SDNG +W+EHT ++ + D L E I E Q N + R +T PQYF+++SR++Q++ IG EGG V+S+V QVQAVFP+GAL KKIK+ LQ + +L K G GVA+SPIVT+EPRRRKFH+AITL++P P Y+ T +LRLLCSI+G + WED+TG++PLT + CVSFTTT+SAR WL+DC ++ ++A+ LY+E VPFI +F+VF ++ E ++R C+TDD +KTLE E + ++ VEVLE ++E +GN++P+T S +QL ++ F+ENRL F R+KD G+ FM++P++ G P PQ+PIC L+I LP E D D+ RT + S ++ I +++ +G DW +L +G+ EEI I Q+ D I KD ++ + LE +L++IGR+DI+K C
Sbjct: 928 FLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGNTPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAK---------GEP-----PQQPICILNIVLP------------EAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNT---DSIARQAQSMIRLYKDKPNYDILS-LETALKNIGRDDIMKKC 1497 HSP 3 Score: 305.834 bits (782), Expect = 3.143e-83 Identity = 217/679 (31.96%), Postives = 332/679 (48.90%), Query Frame = 2
Query: 725 GFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHI---------------------------------ACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLH--P------------------------------EANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
G T AA N+ ++ N D+N N + LH+A+K G ++ L+ + A V+S T+ G + +H A+ +G E ++ +LLE+ A + +S+NG T L MA Q + V + L++ G + T D T ALH+AA ++ AA +LL N+ N + + +GFTPLHI A K ++ MV LL++ +I + T GLTPLH AA G +++V++LL+ GA IS T LH+AA+ + +ILL H P A+ NARA TPLHIA + +VE LL GA + T+ T LH+AA G I LL+H PD T +G TPLH+A++ + + R +LL ++ TPLH+A+ + +++ LLL A V+ K+ YT LH+ AK+ EV +LI+ GA ++A ++KGFTPLHL + G+ ++ +LLL ADV+ Q +NG+T LH+A N + LL+ A + G+T LH A Q+ LL+ NA++ G T LHL++Q+GH I LL++++ VNH K GLT + + ++ +N+AE L K
Sbjct: 11 GNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIR-ILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 688 HSP 4 Score: 280.026 bits (715), Expect = 2.830e-75 Identity = 193/556 (34.71%), Postives = 291/556 (52.34%), Query Frame = 2
Query: 905 NSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCE-NALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLL-----LSAKVN----PNSLGHHG-----------------------LTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
N DG + AAR+G +L L+N DI + NGL AL +A++ V L+ +G VD+ T TALH+A+ G ++LL++N +VN ++ NGFTPL++A ++ +V LL+ A+ + TE G TPL +A G ++V +LL+ S T K ALH+AA+ + + LLL + N + ++ TPLHIA GN +I L+ GAD N K N + LH+AAK G+ + LLLE +AKT+ G TPLH A++ G QV LL +SAK P + G LT LHVA + H + +LLLD A+ N NG+TPLH+ KKN ++V +LL+ GA+++A ++ G TPLH+ + G I+ LL +A + G T LHLAA N+TDI+ LL+ A + + + T LH A G + V +LLQ V+A T T+LH+AA++G + +L++N ++ K+G T L + K ++ +A+ L
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE-----SDTRGKVRLPALHIAAKKDDVKA-ATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLL 554
BLAST of Ankyrin-2 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303115) HSP 1 Score: 855.899 bits (2210), Expect = 0.000e+0 Identity = 443/804 (55.10%), Postives = 587/804 (73.01%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMM---SGSEEKKLILDQPEKM 2551
+FLRAAR+GN+E+V E L+ +I + SNANGLNA+HLA+K+G+ VV L+ G VD AT+KGNT+LHIASLAG+ EVV LLLE A++NV+SQNGFTPLYMAAQENH VV++LL GANQ++ T+DGFTPLAVA+QQG+DKVV +LL++D+R KVRLPALHIAAKKDDV AA+LL+ +D N D S SGFTPLHIA+HY N N+A LLI+K ADVN+ AK+NI+PLHVAAKWGK M+ LL+ + N+ + TRDGL+P+HCAARSG E ++ +LLE GA I K+KNGL L MA QG+ + + L+ VD VT+DYLTALHVAAHCG++ A++LL N + NARALNGFTPLHIACKK + K+VELL+++ A I++TTE+GLTPLH+AAFMG IV LL++ AS T++ E LHLAAR NQ + +ILL + A +ARARE QTPLHIA R+GN IV LL GA + TKD YTALHIAAKEG+ E++ +L+E+ DA TKKGFTPLH+ +KYG ++VA QLLL + + ++ G +G+TPLHVA +YN+ ++ LLL+ A+ + KNG+TPLH+ A+KN +++ L++ GA NA+S+ GFTPLHL+S G+ EI LL++ A VNH A+NGLT +HL A+++ ++ E L K A+I T+ GYT LH A HFGQ V+ LLQ +V+A T++G T LH AQQGH IV LLL+++ + N Q G T L +A+K Y+++ ++L +T E S +EEK ++ PE M
Sbjct: 164 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLL-DNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRN-GAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVA-QLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVV-APEAM 963 HSP 2 Score: 435.647 bits (1119), Expect = 2.882e-124 Identity = 234/600 (39.00%), Postives = 347/600 (57.83%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKS-----------ELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTC 4635
FL+SF+VDA+GG M+ RH +R+ +P S PTR+ C + + P L + EALA R++ L + GP+++E+PH A+LR ERE+++L+SDNG +W+EHT ++ + D L E I E Q N + R +T PQYF+++SR++Q++ IG EGG V+S+V QVQAVFP+GAL KKIK+ LQ + +L K G GVA+SPIVT+EPRRRKFH+AITL++P P Y+ T +LRLLCSI+G + WED+TG++PLT + CVSFTTT+SAR WL+DC ++ ++A+ LY+E VPFI +F+VF ++ E ++R C+TDD +KTLE E + ++ VEVLE ++E +GN++P+T S +QL ++ F+ENRL F R+KD G+ FM++P++ G P PQ+PIC L+I LP E D D+ RT + S ++ I +++ +G DW +L +G+ EEI I Q+ D I KD ++ + LE +L++IGR+DI+K C
Sbjct: 1109 FLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGNTPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAK---------GEP-----PQQPICILNIVLP------------EAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNT---DSIARQAQSMIRLYKDKPNYDILS-LETALKNIGRDDIMKKC 1678 HSP 3 Score: 309.301 bits (791), Expect = 3.033e-84 Identity = 221/685 (32.26%), Postives = 336/685 (49.05%), Query Frame = 2
Query: 710 HQSA-SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHI---------------------------------ACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLH--P------------------------------EANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
HQSA G T AA N+ ++ N D+N N + LH+A+K G ++ L+ + A V+S T+ G + +H A+ +G E ++ +LLE+ A + +S+NG T L MA Q + V + L++ G + T D T ALH+AA ++ AA +LL N+ N + + +GFTPLHI A K ++ MV LL++ +I + T GLTPLH AA G +++V++LL+ GA IS T LH+AA+ + +ILL H P A+ NARA TPLHIA + +VE LL GA + T+ T LH+AA G I LL+H PD T +G TPLH+A++ + + R +LL ++ TPLH+A+ + +++ LLL A V+ K+ YT LH+ AK+ EV +LI+ GA ++A ++KGFTPLHL + G+ ++ +LLL ADV+ Q +NG+T LH+A N + LL+ A + G+T LH A Q+ LL+ NA++ G T LHL++Q+GH I LL++++ VNH K GLT + + ++ +N+AE L K
Sbjct: 155 HQSAGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIR-ILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 838
BLAST of Ankyrin-2 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0344223) HSP 1 Score: 855.899 bits (2210), Expect = 0.000e+0 Identity = 443/804 (55.10%), Postives = 587/804 (73.01%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMM---SGSEEKKLILDQPEKM 2551
+FLRAAR+GN+E+V E L+ +I + SNANGLNA+HLA+K+G+ VV L+ G VD AT+KGNT+LHIASLAG+ EVV LLLE A++NV+SQNGFTPLYMAAQENH VV++LL GANQ++ T+DGFTPLAVA+QQG+DKVV +LL++D+R KVRLPALHIAAKKDDV AA+LL+ +D N D S SGFTPLHIA+HY N N+A LLI+K ADVN+ AK+NI+PLHVAAKWGK M+ LL+ + N+ + TRDGL+P+HCAARSG E ++ +LLE GA I K+KNGL L MA QG+ + + L+ VD VT+DYLTALHVAAHCG++ A++LL N + NARALNGFTPLHIACKK + K+VELL+++ A I++TTE+GLTPLH+AAFMG IV LL++ AS T++ E LHLAAR NQ + +ILL + A +ARARE QTPLHIA R+GN IV LL GA + TKD YTALHIAAKEG+ E++ +L+E+ DA TKKGFTPLH+ +KYG ++VA QLLL + + ++ G +G+TPLHVA +YN+ ++ LLL+ A+ + KNG+TPLH+ A+KN +++ L++ GA NA+S+ GFTPLHL+S G+ EI LL++ A VNH A+NGLT +HL A+++ ++ E L K A+I T+ GYT LH A HFGQ V+ LLQ +V+A T++G T LH AQQGH IV LLL+++ + N Q G T L +A+K Y+++ ++L +T E S +EEK ++ PE M
Sbjct: 164 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLL-DNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRN-GAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVA-QLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVV-APEAM 963 HSP 2 Score: 436.417 bits (1121), Expect = 1.814e-124 Identity = 234/600 (39.00%), Postives = 347/600 (57.83%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKS-----------ELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTC 4635
FL+SF+VDA+GG M+ RH +R+ +P S PTR+ C + + P L + EALA R++ L + GP+++E+PH A+LR ERE+++L+SDNG +W+EHT ++ + D L E I E Q N + R +T PQYF+++SR++Q++ IG EGG V+S+V QVQAVFP+GAL KKIK+ LQ + +L K G GVA+SPIVT+EPRRRKFH+AITL++P P Y+ T +LRLLCSI+G + WED+TG++PLT + CVSFTTT+SAR WL+DC ++ ++A+ LY+E VPFI +F+VF ++ E ++R C+TDD +KTLE E + ++ VEVLE ++E +GN++P+T S +QL ++ F+ENRL F R+KD G+ FM++P++ G P PQ+PIC L+I LP E D D+ RT + S ++ I +++ +G DW +L +G+ EEI I Q+ D I KD ++ + LE +L++IGR+DI+K C
Sbjct: 1078 FLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGNTPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAK---------GEP-----PQQPICILNIVLP------------EAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNT---DSIARQAQSMIRLYKDKPNYDILS-LETALKNIGRDDIMKKC 1647 HSP 3 Score: 309.301 bits (791), Expect = 3.108e-84 Identity = 221/685 (32.26%), Postives = 336/685 (49.05%), Query Frame = 2
Query: 710 HQSA-SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHI---------------------------------ACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLH--P------------------------------EANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
HQSA G T AA N+ ++ N D+N N + LH+A+K G ++ L+ + A V+S T+ G + +H A+ +G E ++ +LLE+ A + +S+NG T L MA Q + V + L++ G + T D T ALH+AA ++ AA +LL N+ N + + +GFTPLHI A K ++ MV LL++ +I + T GLTPLH AA G +++V++LL+ GA IS T LH+AA+ + +ILL H P A+ NARA TPLHIA + +VE LL GA + T+ T LH+AA G I LL+H PD T +G TPLH+A++ + + R +LL ++ TPLH+A+ + +++ LLL A V+ K+ YT LH+ AK+ EV +LI+ GA ++A ++KGFTPLHL + G+ ++ +LLL ADV+ Q +NG+T LH+A N + LL+ A + G+T LH A Q+ LL+ NA++ G T LHL++Q+GH I LL++++ VNH K GLT + + ++ +N+AE L K
Sbjct: 155 HQSAGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIR-ILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 838
BLAST of Ankyrin-2 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303121) HSP 1 Score: 855.514 bits (2209), Expect = 0.000e+0 Identity = 443/804 (55.10%), Postives = 587/804 (73.01%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMM---SGSEEKKLILDQPEKM 2551
+FLRAAR+GN+E+V E L+ +I + SNANGLNA+HLA+K+G+ VV L+ G VD AT+KGNT+LHIASLAG+ EVV LLLE A++NV+SQNGFTPLYMAAQENH VV++LL GANQ++ T+DGFTPLAVA+QQG+DKVV +LL++D+R KVRLPALHIAAKKDDV AA+LL+ +D N D S SGFTPLHIA+HY N N+A LLI+K ADVN+ AK+NI+PLHVAAKWGK M+ LL+ + N+ + TRDGL+P+HCAARSG E ++ +LLE GA I K+KNGL L MA QG+ + + L+ VD VT+DYLTALHVAAHCG++ A++LL N + NARALNGFTPLHIACKK + K+VELL+++ A I++TTE+GLTPLH+AAFMG IV LL++ AS T++ E LHLAAR NQ + +ILL + A +ARARE QTPLHIA R+GN IV LL GA + TKD YTALHIAAKEG+ E++ +L+E+ DA TKKGFTPLH+ +KYG ++VA QLLL + + ++ G +G+TPLHVA +YN+ ++ LLL+ A+ + KNG+TPLH+ A+KN +++ L++ GA NA+S+ GFTPLHL+S G+ EI LL++ A VNH A+NGLT +HL A+++ ++ E L K A+I T+ GYT LH A HFGQ V+ LLQ +V+A T++G T LH AQQGH IV LLL+++ + N Q G T L +A+K Y+++ ++L +T E S +EEK ++ PE M
Sbjct: 14 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLL-DNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRN-GAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVA-QLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVV-APEAM 813 HSP 2 Score: 436.417 bits (1121), Expect = 1.916e-124 Identity = 234/600 (39.00%), Postives = 347/600 (57.83%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNL--AENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKS-----------ELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTC 4635
FL+SF+VDA+GG M+ RH +R+ +P S PTR+ C + + P L + EALA R++ L + GP+++E+PH A+LR ERE+++L+SDNG +W+EHT ++ + D L E I E Q N + R +T PQYF+++SR++Q++ IG EGG V+S+V QVQAVFP+GAL KKIK+ LQ + +L K G GVA+SPIVT+EPRRRKFH+AITL++P P Y+ T +LRLLCSI+G + WED+TG++PLT + CVSFTTT+SAR WL+DC ++ ++A+ LY+E VPFI +F+VF ++ E ++R C+TDD +KTLE E + ++ VEVLE ++E +GN++P+T S +QL ++ F+ENRL F R+KD G+ FM++P++ G P PQ+PIC L+I LP E D D+ RT + S ++ I +++ +G DW +L +G+ EEI I Q+ D I KD ++ + LE +L++IGR+DI+K C
Sbjct: 959 FLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIGPVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGNTPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAK---------GEP-----PQQPICILNIVLP------------EAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNT---DSIARQAQSMIRLYKDKPNYDILS-LETALKNIGRDDIMKKC 1528 HSP 3 Score: 305.449 bits (781), Expect = 3.875e-83 Identity = 217/679 (31.96%), Postives = 332/679 (48.90%), Query Frame = 2
Query: 725 GFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-----------------------------ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHI---------------------------------ACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLH--P------------------------------EANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
G T AA N+ ++ N D+N N + LH+A+K G ++ L+ + A V+S T+ G + +H A+ +G E ++ +LLE+ A + +S+NG T L MA Q + V + L++ G + T D T ALH+AA ++ AA +LL N+ N + + +GFTPLHI A K ++ MV LL++ +I + T GLTPLH AA G +++V++LL+ GA IS T LH+AA+ + +ILL H P A+ NARA TPLHIA + +VE LL GA + T+ T LH+AA G I LL+H PD T +G TPLH+A++ + + R +LL ++ TPLH+A+ + +++ LLL A V+ K+ YT LH+ AK+ EV +LI+ GA ++A ++KGFTPLHL + G+ ++ +LLL ADV+ Q +NG+T LH+A N + LL+ A + G+T LH A Q+ LL+ NA++ G T LHL++Q+GH I LL++++ VNH K GLT + + ++ +N+AE L K
Sbjct: 11 GNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIR-ILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEK 688 HSP 4 Score: 280.026 bits (715), Expect = 3.254e-75 Identity = 203/584 (34.76%), Postives = 295/584 (50.51%), Query Frame = 2
Query: 905 NSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCE-NALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLL-----LSAKVN----PNSLGHHG-----------------------LTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTK-----------TQMG----------------------YTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLN 2458
N DG + AAR+G +L L+N DI + NGL AL +A++ V L+ +G VD+ T TALH+A+ G ++LL++N +VN ++ NGFTPL++A ++ +V LL+ A+ + TE G TPL +A G ++V +LL+ S T K ALH+AA+ + + LLL + N + ++ TPLHIA GN +I L+ GAD N K N + LH+AAK G+ + LLLE +AKT+ G TPLH A++ G QV LL +SAK P + G LT LHVA + H + +LLLD A+ N NG+TPLH+ KKN ++V +LL+ GA+++A ++ G TPLH+ + G I+ LL +A + G T LHLAA N+TDI+ LL+ A + + +++G YTALH A GQ + +L++ ++A T G T LHL A+ GHI + +LLL E DV+ Q K G+T L VA HY N
Sbjct: 5 NGAQGDGNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE-----SDTRGKVRLPALHIAAKKDDVKA-ATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVA--CHYNN 580
BLAST of Ankyrin-2 vs. Ensembl Zebrafish
Match: ank2b (ankyrin 2b, neuronal [Source:ZFIN;Acc:ZDB-GENE-041010-165]) HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0 Identity = 422/803 (52.55%), Postives = 565/803 (70.36%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ + SN NGLNA+HLAAKEG+ ++VQ L+ G SVD AT+KGNT+LHIASLAG+ +VV +L + ANIN +SQNGFTPLYMA+QENHLDVV+ LLE G NQ+I T+DGFTPLA+ALQQG+++VV ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+ LL+ + A +++ TRDGL+P+HCAARSG + + +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELLIKY A I + TE+GLTP+H+AAFMG IV +LL+NGAS + ++ E ALH+AAR Q E + LL + A +ARARE+QTPLHIA R+G IV+ LL A P+ T + YT LHIAA+EG +++ +LLE TKKGFTPLH+ASKYG ++VA+ LLL + P+S G +GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +E+ L+ GA N Q+++G P+HL S G+ E+ LLL A VN ++GLT+LHLAA++++ + E L+K A++ +T++GYT L A H+G + V LL+ VN +T G T LH AAQQG+ I+ +LL N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 23 SFLRAARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRN-GAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAK-LLLQRRAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRGAQVNVTTKSGLTSLHLAAQEDKVGVGEILVKQGANLDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAITVNGNTALAIARRLGYISVVDTLRVVTEEIVTTTTTVTEKHKLNVPETMTE 822 HSP 2 Score: 446.432 bits (1147), Expect = 2.552e-129 Identity = 239/629 (38.00%), Postives = 358/629 (56.92%), Query Frame = 1
Query: 2815 NDWEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-DANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLG-NQLELSLRDIGREDIVKTCIHDI--SIVDESERKFAE 4683
+ WE E LD++ L P +GFL+SF+VDA+GG M+ RH +R+ +P PTR+ C L ++ T+P + + + LA R+I + S GP+++EIPH AALR ERE+V+L+S+ G SWKEH +T+ + L + E + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V +VQAVFPEGAL K+I++ LQ + ++++ GN SPIVTLEPRRRKFH+ IT+T+P+P S D +T +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V A+ +Y E VP++ +F++F + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL+ + +I+D + PCG+++F ++PR + L +C L+I+LP L D+ +P D+ +R E + +A +G W +L L +I +I ++ + +D+++ + LW K+ + N N L +L I R DIV I S D S +AE
Sbjct: 917 DSWETENLDNIALSSSPAHSGFLVSFMVDARGGAMRGCRHNGLRLIIPPRKCSAPTRVTCRLVKRHRLATMPPMVEGDGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVILRSETGESWKEHHCEYTEEELNQVLNGMDERLDPPEELEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPEVQAVFPEGALTKRIRVGLQTQPMSVDVVRNMLGNKATFSPIVTLEPRRRKFHKPITMTIPVPKSSADPALGSFGGGETPTLRLLCSITGGTTPAQWEDITGTTPLTFTNDCVSFTTNVSARFWLIDCRQVQESVNFATLMYREIICVPYMAKFVIFAKTHDPIEARLRCFCMTDDKMDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHVFSFYAFKENRLALFIKIRDNTQEPCGRLSFTKEPRS---------------FRTLSHGAVCNLNISLPAYSKAAFL---------DIAVDPQDEADR-------KESRLAVIANHLGFSWSELARELEFSDVQINQIRNENPNSLQDQSHALIRLW----KEREGKNASENSLMKTLTKINRMDIVHLIETKIIQSSQDHSSHTYAE 1510 HSP 3 Score: 275.404 bits (703), Expect = 5.003e-74 Identity = 190/616 (30.84%), Postives = 306/616 (49.68%), Query Frame = 2
Query: 812 PAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPL-----------------------------HIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGA----------DP-----------------------NMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
P ++ T AA+ G + + + ++ + ++GL+ +H AA+ G +++ LL G+ + +K G TAL +A+ Q +V K L +G +++A + + T L++A+ +++ LL+N N + +GFTPL HIA +K +K LL++ + + +++G TPLHIAA G+ + +LL GA++ T LH+A++ LLL A +A+ R+ TPLH A R G+ + VE LL GA P + VT D TALH+AA G + +++LLL+ + P+A+ GFTPLHIA K RV+V +LL+ ++ GLTP+HVA + H ++ LLL A+ + G T LH+ A+ +EV + L+ GA V+A++++ TPLH+ S G EI++LLL A + NG T LH+AA + D+ LL+ A S T+ G+T LH A +G ++ K+LLQ+ ++ G T LH+AA + + LLLD + K G T L +A K++ + IA TL
Sbjct: 16 PKSDSNTSFLRAARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVH-LLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVM-ELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTL 629 HSP 4 Score: 169.474 bits (428), Expect = 1.662e-41 Identity = 115/346 (33.24%), Postives = 175/346 (50.58%), Query Frame = 2
Query: 1487 PEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTP-----------------------------LHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVA 2437
P A+ ++ T A R GN V + L G D ++ ALH+AAKEG ++ + LL D+ TKKG T LHIAS G+ V + +L N N+ +G TPL++A+ NH +++ LL+ N + ++G+TP LH+ A+K+ + LL+ N + QS+ GFTPLH+ + GN + LLL+ A V+ A NG+T LH+A+++ T++V LL A I KT+ G T LH A G V++LL++ + A+T G + LH+AAQ H+ V+ LL ++ V+ LTAL VA
Sbjct: 9 PTAHNQPPKSDSNTSFLRAARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVK-ILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVA 353
BLAST of Ankyrin-2 vs. Ensembl Zebrafish
Match: ank2b (ankyrin 2b, neuronal [Source:ZFIN;Acc:ZDB-GENE-041010-165]) HSP 1 Score: 797.734 bits (2059), Expect = 0.000e+0 Identity = 422/804 (52.49%), Postives = 565/804 (70.27%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLG-HHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ + SN NGLNA+HLAAKEG+ ++VQ L+ G SVD AT+KGNT+LHIASLAG+ +VV +L + ANIN +SQNGFTPLYMA+QENHLDVV+ LLE G NQ+I T+DGFTPLA+ALQQG+++VV ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+ LL+ + A +++ TRDGL+P+HCAARSG + + +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELLIKY A I + TE+GLTP+H+AAFMG IV +LL+NGAS + ++ E ALH+AAR Q E + LL + A +ARARE+QTPLHIA R+G IV+ LL A P+ T + YT LHIAA+EG +++ +LLE TKKGFTPLH+ASKYG ++VA+ LLL + P+S G +GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +E+ L+ GA N Q+++G P+HL S G+ E+ LLL A VN ++GLT+LHLAA++++ + E L+K A++ +T++GYT L A H+G + V LL+ VN +T G T LH AAQQG+ I+ +LL N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 35 SFLRAARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRN-GAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAK-LLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRGAQVNVTTKSGLTSLHLAAQEDKVGVGEILVKQGANLDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAIT-NGNTALAIARRLGYISVVDTLRVVTEEIVTTTTTVTEKHKLNVPETMTE 834 HSP 2 Score: 423.32 bits (1087), Expect = 3.289e-120 Identity = 218/562 (38.79%), Postives = 325/562 (57.83%), Query Frame = 1
Query: 2815 NDWEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRII-------------HLNASTQSLD--------------------GPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-DANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSEL 4395
+ WE E LD++ L P +GFL+SF+VDA+GG M+ RH +R+ +P PTR+ C L ++ T+P + + + LA R+I HL + L+ GP+++EIPH AALR ERE+V+L+S+ G SWKEH +T+ + L + E + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V +VQAVFPEGAL K+I++ LQ + ++++ GN SPIVTLEPRRRKFH+ IT+T+P+P S D +T +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V A+ +Y E VP++ +F++F + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL+ + +I+D + PCG+++F ++PR S + +G V C L+I+LP + + +E ++ + DD E +I+K+ L
Sbjct: 923 DSWETENLDNIALSSSPAHSGFLVSFMVDARGGAMRGCRHNGLRLIIPPRKCSAPTRVTCRLVKRHRLATMPPMVEGDGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVILRSETGESWKEHHCEYTEEELNQVLNGMDERLDPPEELEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPEVQAVFPEGALTKRIRVGLQTQPMSVDVVRNMLGNKATFSPIVTLEPRRRKFHKPITMTIPVPKSSADPALGSFGGGETPTLRLLCSITGGTTPAQWEDITGTTPLTFTNDCVSFTTNVSARFWLIDCRQVQESVNFATLMYREIICVPYMAKFVIFAKTHDPIEARLRCFCMTDDKMDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHVFSFYAFKENRLALFIKIRDNTQEPCGRLSFTKEPR--SFRTLSHGAV-------------CNLNISLPAYSKESDSDQEPDEETSRTLGKYDDDTETTETSILKTHL 1469 HSP 3 Score: 241.891 bits (616), Expect = 1.820e-63 Identity = 178/558 (31.90%), Postives = 279/558 (50.00%), Query Frame = 2
Query: 1010 KSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTT--------------------MKCEN---------ALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTP---------------------------------LHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
KS + + L+ A G+ +V + L G+D+ + L ALH+AA G+++ + LL +V++ G T LHIA Q +V++L K A+IN+ ++ G TPL++A+ ++V LL+NG + S T + EN ALH+AAR + ++ LLL + N + +++ TPLHIA GN ++ LLN GA + ++ T LH+A+K G + LLL+ + DAKT+ G TPLH A++ G A +LLL + +GL+P LHVA + HY + +LLLD AN N NG+TPLH+ KKN ++V +LLI GA + A ++ G TP+H+ + G+ I+ LLL A + G TALH+AA + ++V LL+ A + + + T LH A G+ + V++LLQ +A T G T LH+AA++GH+ + +LL+ + K+G T L VA K L +A+ L + P+
Sbjct: 29 KSDSNTSFLRAARAGNIDKVLEYL-KGGVDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKS-AALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGH-DTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPD 583
BLAST of Ankyrin-2 vs. Ensembl Zebrafish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 787.719 bits (2033), Expect = 0.000e+0 Identity = 405/779 (51.99%), Postives = 554/779 (71.12%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
++LRAAR+GN+EKV ++L+ + ++ N NGLNA+HLA+KEG+ EVV L++ G +VD AT+KGNT+LHIASLAG+ EVV L+ + AN+N +SQNGFTPLYMAAQENHLDVV+ LLE ++Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + + + T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A + + TE+GLTP+H+AAFMG + IV L +GAS + T ++ E ALH+AAR Q + + LL + A + +A+++QT LHIA R+G IV+QLL GA PN T YT LH++A+EG EI+ LLLE A TKKGFTPLH+A+KYG+++VA LLL K P++ G GLTPLHVA +Y++ + LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA N +++G +PLHL + G+ +++ LLL A+VN +NGLT LHLAA+ ++ + E LL A+I +T+ GYT LH A H+G ++ LL+ NA+T G T LH AAQQGH I+ +LL N G TAL +A++ Y+++ +TL VT
Sbjct: 45 SYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQN-GAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVA-NLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVT 820 HSP 2 Score: 411.379 bits (1056), Expect = 1.905e-117 Identity = 225/637 (35.32%), Postives = 344/637 (54.00%), Query Frame = 1
Query: 2860 PVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-----DANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV---KTCIHDISIVDESERKFAETIING 4698
PV +GFL+SF+VDA+GG M+ RH +RI VP PTRI C L ++ P + + E L R++ + + GP+++EIPH ++R ERE++VL+SDNG +WKEH + L + E + + + RI RIIT PQYF+++SR+KQ+ +G EGG + S V+A FP+GAL KKI++ LQ + ++++ GN + SPIVT+EPRRRKFH+ IT+T+P+P S + + P LRLLCSI+G +P WEDITGT+PL+ CVSFTT +SAR WL DC + +E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +E+LE E GNI P+ S +QL F+ENRL F +++D+ PCG+++F+ +P+ + LPQ IC L+ TLPT ++ ++ D+E D + +P + C +++L + VA +G W +L + +EI I ++ + ++++ L W++ K+ + L L + R DIV + I D E+ AE +G
Sbjct: 972 PVHSGFLVSFMVDARGGSMRGSRHDGMRIIVPPRKCPAPTRITCRLAKRHRLAYPPPMVEGEGLVSRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSDNGETWKEHHYDCKVTELTSILNGMDEEMDSPAELEKKRICRIITKDFPQYFAVVSRIKQESDHMGPEGGVLTSEAVPMVKAAFPQGALTKKIRVGLQAQPVPEDMVRTIIGNRASFSPIVTVEPRRRKFHKPITMTIPVPPRSKEAVANGRKGEP----APCLRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTNVSARFWLADCQQISETVGLASQLYRELICVPYLAKFVVFAKMIDHIEFSMRCFCMTDDKVDKTLEQQENFEEVARSKDIEILEGKPIHGECYGNIYPLAKSGQQLIFNFYAFKENRLPFNIKVRDIGQEPCGRISFLREPKT---------------AKGLPQSAICNLNFTLPTH-RKEMESDPDDENDKDRRHTFASLALRKRYSYLADPASSPQSPCE---RTDLRMAIVADHLGLSWTELAREMNFSVDEINHIRTENPNSLTAQSFMLLKKWVSRDG---KNATTDALTAVLTKVNRMDIVTLLEGPIFDYGWFSETSNANAEPAASG 1582 HSP 3 Score: 296.975 bits (759), Expect = 1.006e-80 Identity = 193/551 (35.03%), Postives = 294/551 (53.36%), Query Frame = 2
Query: 944 AARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCE-NALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVAR--------------------------------QLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
AAR+G +L L+ G DI ++NGL AL +A++ EV L+ G +VDA T TALH+A+ G L+ N NVNA++ NGFTPL++A ++ +V L++ + + TE G TPL +A G ++V++LL+N T K ALH+AAR + ++ LLL + N + ++ TPLHIA GN ++ LLN GA + + +++ T LH+A+K G + +LLL+ K +AKTK G TPLH ++ G QV QLLL + + + LT LHVA + HY++ ++++D +AN N NG+TPLH+ KKN ++V +LL+ GA++ A ++ G TP+H+ + G++ I++ L A N G TALH+AA + D+V LL+ A + K + TALH A G+++ V+ LLQK NA T G T LHL+A++GH I LLL+ ++ K+G T L VA K L +A L + P+
Sbjct: 49 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKS-AALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPD 593
BLAST of Ankyrin-2 vs. Ensembl Zebrafish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 787.719 bits (2033), Expect = 0.000e+0 Identity = 405/779 (51.99%), Postives = 554/779 (71.12%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
++LRAAR+GN+EKV ++L+ + ++ N NGLNA+HLA+KEG+ EVV L++ G +VD AT+KGNT+LHIASLAG+ EVV L+ + AN+N +SQNGFTPLYMAAQENHLDVV+ LLE ++Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + + + T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A + + TE+GLTP+H+AAFMG + IV L +GAS + T ++ E ALH+AAR Q + + LL + A + +A+++QT LHIA R+G IV+QLL GA PN T YT LH++A+EG EI+ LLLE A TKKGFTPLH+A+KYG+++VA LLL K P++ G GLTPLHVA +Y++ + LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA N +++G +PLHL + G+ +++ LLL A+VN +NGLT LHLAA+ ++ + E LL A+I +T+ GYT LH A H+G ++ LL+ NA+T G T LH AAQQGH I+ +LL N G TAL +A++ Y+++ +TL VT
Sbjct: 45 SYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQN-GAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVA-NLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVT 820 HSP 2 Score: 411.379 bits (1056), Expect = 1.905e-117 Identity = 225/637 (35.32%), Postives = 344/637 (54.00%), Query Frame = 1
Query: 2860 PVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-----DANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV---KTCIHDISIVDESERKFAETIING 4698
PV +GFL+SF+VDA+GG M+ RH +RI VP PTRI C L ++ P + + E L R++ + + GP+++EIPH ++R ERE++VL+SDNG +WKEH + L + E + + + RI RIIT PQYF+++SR+KQ+ +G EGG + S V+A FP+GAL KKI++ LQ + ++++ GN + SPIVT+EPRRRKFH+ IT+T+P+P S + + P LRLLCSI+G +P WEDITGT+PL+ CVSFTT +SAR WL DC + +E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +E+LE E GNI P+ S +QL F+ENRL F +++D+ PCG+++F+ +P+ + LPQ IC L+ TLPT ++ ++ D+E D + +P + C +++L + VA +G W +L + +EI I ++ + ++++ L W++ K+ + L L + R DIV + I D E+ AE +G
Sbjct: 972 PVHSGFLVSFMVDARGGSMRGSRHDGMRIIVPPRKCPAPTRITCRLAKRHRLAYPPPMVEGEGLVSRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSDNGETWKEHHYDCKVTELTSILNGMDEEMDSPAELEKKRICRIITKDFPQYFAVVSRIKQESDHMGPEGGVLTSEAVPMVKAAFPQGALTKKIRVGLQAQPVPEDMVRTIIGNRASFSPIVTVEPRRRKFHKPITMTIPVPPRSKEAVANGRKGEP----APCLRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTNVSARFWLADCQQISETVGLASQLYRELICVPYLAKFVVFAKMIDHIEFSMRCFCMTDDKVDKTLEQQENFEEVARSKDIEILEGKPIHGECYGNIYPLAKSGQQLIFNFYAFKENRLPFNIKVRDIGQEPCGRISFLREPKT---------------AKGLPQSAICNLNFTLPTH-RKEMESDPDDENDKDRRHTFASLALRKRYSYLADPASSPQSPCE---RTDLRMAIVADHLGLSWTELAREMNFSVDEINHIRTENPNSLTAQSFMLLKKWVSRDG---KNATTDALTAVLTKVNRMDIVTLLEGPIFDYGWFSETSNANAEPAASG 1582 HSP 3 Score: 296.975 bits (759), Expect = 1.006e-80 Identity = 193/551 (35.03%), Postives = 294/551 (53.36%), Query Frame = 2
Query: 944 AARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCE-NALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVAR--------------------------------QLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
AAR+G +L L+ G DI ++NGL AL +A++ EV L+ G +VDA T TALH+A+ G L+ N NVNA++ NGFTPL++A ++ +V L++ + + TE G TPL +A G ++V++LL+N T K ALH+AAR + ++ LLL + N + ++ TPLHIA GN ++ LLN GA + + +++ T LH+A+K G + +LLL+ K +AKTK G TPLH ++ G QV QLLL + + + LT LHVA + HY++ ++++D +AN N NG+TPLH+ KKN ++V +LL+ GA++ A ++ G TP+H+ + G++ I++ L A N G TALH+AA + D+V LL+ A + K + TALH A G+++ V+ LLQK NA T G T LHL+A++GH I LLL+ ++ K+G T L VA K L +A L + P+
Sbjct: 49 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKS-AALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPD 593
BLAST of Ankyrin-2 vs. Ensembl Zebrafish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 785.023 bits (2026), Expect = 0.000e+0 Identity = 405/787 (51.46%), Postives = 554/787 (70.39%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSA--------SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
++LRAAR+GN+EKV ++L+ + ++ N NGLNA+HLA+KEG+ EVV L++ G +VD AT+KGNT+LHIASLAG+ EVV L+ + AN+N +SQNGFTPLYMAAQENHLDVV+ LLE ++Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + + + T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A + + TE+GLTP+H+AAFMG + IV L +GAS + T ++ E ALH+AAR Q + + LL + A + +A+++QT LHIA R+G IV+QLL GA PN T YT LH++A+EG EI+ LLLE A TKKGFTPLH+A+KYG+++VA LLL K P++ G GLTPLHVA +Y++ + LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA N +++G +PLHL + G+ +++ LLL A+VN +NGLT LHLAA+ ++ + E LL A+I +T+ GYT LH A H+G ++ LL+ NA+T G T LH AAQQGH I+ +LL N G TAL +A++ Y+++ +TL VT
Sbjct: 28 SYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVESKMMVNRTTESGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQN-GAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVA-NLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVT 811 HSP 2 Score: 400.208 bits (1027), Expect = 9.400e-113 Identity = 193/474 (40.72%), Postives = 280/474 (59.07%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-----DANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT 4281
FL+SF+VDA+GG M+ RH +RI VP PTRI C L ++ P + + E L R++ + + GP+++EIPH ++R ERE++VL+SDNG +WKEH + L + E + + + RI RIIT PQYF+++SR+KQ+ +G EGG + S V+A FP+GAL KKI++ LQ + ++++ GN + SPIVT+EPRRRKFH+ IT+T+P+P S + + P LRLLCSI+G +P WEDITGT+PL+ CVSFTT +SAR WL DC + +E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +E+LE E GNI P+ S +QL F+ENRL F +++D+ PCG+++F+ +P+ + LPQ IC L+ TLPT
Sbjct: 967 FLVSFMVDARGGSMRGSRHDGMRIIVPPRKCPAPTRITCRLAKRHRLAYPPPMVEGEGLVSRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSDNGETWKEHHYDCKVTELTSILNGMDEEMDSPAELEKKRICRIITKDFPQYFAVVSRIKQESDHMGPEGGVLTSEAVPMVKAAFPQGALTKKIRVGLQAQPVPEDMVRTIIGNRASFSPIVTVEPRRRKFHKPITMTIPVPPRSKEAVANGRKGEPAPC----LRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTNVSARFWLADCQQISETVGLASQLYRELICVPYLAKFVVFAKMIDHIEFSMRCFCMTDDKVDKTLEQQENFEEVARSKDIEILEGKPIHGECYGNIYPLAKSGQQLIFNFYAFKENRLPFNIKVRDIGQEPCGRISFLREPKT---------------AKGLPQSAICNLNFTLPT 1421 HSP 3 Score: 289.271 bits (739), Expect = 5.876e-78 Identity = 192/558 (34.41%), Postives = 292/558 (52.33%), Query Frame = 2
Query: 944 AARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCE-NALHLAARNNQEETFKILL-------LHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVAR--------------------------------QLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
AAR+G +L L+ G DI ++NGL AL +A++ EV L+ G +VDA T TALH+A+ G L+ N NVNA++ NGFTPL++A ++ +V L++ + + TE G TPL +A G ++V++LL+N T K ALH+AAR + ++ +LL + + N TPLHIA GN ++ LLN GA + + +++ T LH+A+K G + +LLL+ K +AKTK G TPLH ++ G QV QLLL + + + LT LHVA + HY++ ++++D +AN N NG+TPLH+ KKN ++V +LL+ GA++ A ++ G TP+H+ + G++ I++ L A N G TALH+AA + D+V LL+ A + K + TALH A G+++ V+ LLQK NA T G T LHL+A++GH I LLL+ ++ K+G T L VA K L +A L + P+
Sbjct: 32 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKMMVNRTTESGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPD 584
BLAST of Ankyrin-2 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 804.283 bits (2076), Expect = 0.000e+0 Identity = 413/805 (51.30%), Postives = 570/805 (70.81%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
M EETK+ + AH ++LRAARSGN+EK ++L+ + ++ N NGLNA+HLA+KEG+ E+V LI+ G VD +T+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + +++ TRDGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L +GAS + T ++ E ALH+AAR Q E + LL + A A+A+++QTPLHI+ R+G IV+QLL GA P+ T YT LH++++EG +++ +LLEH TKKGFTPLH+A+KYG+++V + LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G P+HL + G+ +++ LLL +A+VN ++GLT LHLAA+++R + E L A I T+M YT LH A H+G I+ V LLQ VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT
Sbjct: 1 MSEETKEKAAKPAHRKRKGKKSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQN-GAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVK-LLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVT 802 HSP 2 Score: 434.491 bits (1116), Expect = 1.878e-124 Identity = 234/631 (37.08%), Postives = 356/631 (56.42%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAG-----------FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +G FL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T P + + E LA R++ + S GP+++EIPH ++R ERE++VL+S+NG +WKEH + + L + E + + E + RI RI+T PQYF+++SR+KQ+ IG EGG + S+ +VQA FPEGAL K+I++ LQ + +L++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ SLRLLCSI+G +P WEDITGT+PLT + CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +++D S PCG+++F+++P+ T+ LPQ +C L+ITLPT+ + + DE D + P + C ++++ + VA +G W +L L +EI +I +++ + ++++ L W+ K+ + L L I R DIV
Sbjct: 928 WAADTLDNVNLVSSPVHSGYVSPLPQYDASFLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLATPPPMVEGEGLASRLVEMGPSGAQFLGPVIVEIPHFGSMRSKERELIVLRSENGENWKEHQYDCRVEELTELLNGMDEELDSAEELEKKRICRIVTKDFPQYFAVVSRIKQESNQIGPEGGVLKSTTVPRVQASFPEGALTKRIRVGLQAQPVPDDLVKKVIGNRATFSPIVTVEPRRRKFHKPITMTIPIPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFVNDCVSFTTNVSARFWLGDCHQIPETVSLATQLYRELICVPYMAKFVVFAKMNDPVEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLIFNFYAFKENRLPFSVKVRDHSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPTQKKETESDQDDENEKVDRRQNFVSLALRKRYSYLTEPGMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLTAQSFMLLKKWVVRDG---KNATTDALTNVLTKINRIDIV 1537
BLAST of Ankyrin-2 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 804.283 bits (2076), Expect = 0.000e+0 Identity = 410/798 (51.38%), Postives = 570/798 (71.43%), Query Frame = 2
Query: 95 RIFQMVEETKDSLTEKAHA-FLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
++FQ + ++S +A +LRAARSGN+EK ++L+ + ++ N NGLNA+HLA+KEG+ E+V LI+ G VD +T+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + +++ TRDGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L +GAS + T ++ E ALH+AAR Q E + LL + A A+A+++QTPLHI+ R+G IV+QLL GA P+ T YT LH++++EG +++ +LLEH TKKGFTPLH+A+KYG+++V + LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G P+HL + G+ +++ LLL +A+VN ++GLT LHLAA+++R + E L A I T+M YT LH A H+G I+ V LLQ VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT
Sbjct: 10 QVFQKISSPRNSPKSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQN-GAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVK-LLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVT 804 HSP 2 Score: 434.106 bits (1115), Expect = 3.249e-124 Identity = 234/631 (37.08%), Postives = 356/631 (56.42%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAG-----------FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +G FL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T P + + E LA R++ + S GP+++EIPH ++R ERE++VL+S+NG +WKEH + + L + E + + E + RI RI+T PQYF+++SR+KQ+ IG EGG + S+ +VQA FPEGAL K+I++ LQ + +L++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ SLRLLCSI+G +P WEDITGT+PLT + CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +++D S PCG+++F+++P+ T+ LPQ +C L+ITLPT+ + + DE D + P + C ++++ + VA +G W +L L +EI +I +++ + ++++ L W+ K+ + L L I R DIV
Sbjct: 930 WAADTLDNVNLVSSPVHSGYVSPLPQYDASFLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLATPPPMVEGEGLASRLVEMGPSGAQFLGPVIVEIPHFGSMRSKERELIVLRSENGENWKEHQYDCRVEELTELLNGMDEELDSAEELEKKRICRIVTKDFPQYFAVVSRIKQESNQIGPEGGVLKSTTVPRVQASFPEGALTKRIRVGLQAQPVPDDLVKKVIGNRATFSPIVTVEPRRRKFHKPITMTIPIPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFVNDCVSFTTNVSARFWLGDCHQIPETVSLATQLYRELICVPYMAKFVVFAKMNDPVEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLIFNFYAFKENRLPFSVKVRDHSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPTQKKETESDQDDENEKVDRRQNFVSLALRKRYSYLTEPGMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLTAQSFMLLKKWVVRDG---KNATTDALTNVLTKINRIDIV 1539
BLAST of Ankyrin-2 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0 Identity = 411/801 (51.31%), Postives = 568/801 (70.91%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
M EETK+ + AH ++LRAARSGN+EK ++L+ + ++ N NGLNA+HLA+KEG+ E+V LI+ G VD +T+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + +++ TRDGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L +GAS + T ++ E ALH+AAR Q E + LL + A A+A+++QTPLHI+ R+G IV+QLL GA P+ T YT LH++++EG +++ +LLEH TKKGFTPLH+A+KYG+++V + LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G P+HL + G+ +++ LLL +A+VN ++GLT LHLAA+++R + E L A I T+M YT LH A H+G I+ V LLQ VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL
Sbjct: 1 MSEETKEKAAKPAHRKRKGKKSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQN-GAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVK-LLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTL 798 HSP 2 Score: 446.432 bits (1147), Expect = 1.249e-128 Identity = 234/605 (38.68%), Postives = 354/605 (58.51%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T P + + E LA R++ + S GP+++EIPH ++R ERE++VL+S+NG +WKEH + + L + E + + E + RI RI+T PQYF+++SR+KQ+ IG EGG + S+ +VQA FPEGAL K+I++ LQ + +L++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ SLRLLCSI+G +P WEDITGT+PLT + CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +++D S PCG+++F+++P+ T+ LPQ +C L+ITLPT+ + ++ S L P ER +++ + VA +G W +L L +EI +I +++ + ++++ L W+ K+ + L L I R DIV
Sbjct: 926 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLATPPPMVEGEGLASRLVEMGPSGAQFLGPVIVEIPHFGSMRSKERELIVLRSENGENWKEHQYDCRVEELTELLNGMDEELDSAEELEKKRICRIVTKDFPQYFAVVSRIKQESNQIGPEGGVLKSTTVPRVQASFPEGALTKRIRVGLQAQPVPDDLVKKVIGNRATFSPIVTVEPRRRKFHKPITMTIPIPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFVNDCVSFTTNVSARFWLGDCHQIPETVSLATQLYRELICVPYMAKFVVFAKMNDPVEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLIFNFYAFKENRLPFSVKVRDHSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPTQKKNEKVDRRQNFVS--LALRPQSPCER-------TDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLTAQSFMLLKKWVVRDG---KNATTDALTNVLTKINRIDIV 1503
BLAST of Ankyrin-2 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 802.357 bits (2071), Expect = 0.000e+0 Identity = 406/779 (52.12%), Postives = 561/779 (72.02%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
++LRAARSGN+EK ++L+ + ++ N NGLNA+HLA+KEG+ E+V LI+ G VD +T+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + +++ TRDGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L +GAS + T ++ E ALH+AAR Q E + LL + A A+A+++QTPLHI+ R+G IV+QLL GA P+ T YT LH++++EG +++ +LLEH TKKGFTPLH+A+KYG+++V + LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G P+HL + G+ +++ LLL +A+VN ++GLT LHLAA+++R + E L A I T+M YT LH A H+G I+ V LLQ VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT
Sbjct: 22 SYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQN-GAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVK-LLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVT 797 HSP 2 Score: 440.269 bits (1131), Expect = 1.760e-125 Identity = 210/490 (42.86%), Postives = 308/490 (62.86%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTK 4284
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T P + + E LA R++ + S GP+++EIPH ++R ERE++VL+S+NG +WKEH + + L + E + + E + RI RI+T PQYF+++SR+KQ+ IG EGG + S+ +VQA FPEGAL K+I++ LQ + +L++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ SLRLLCSI+G +P WEDITGT+PLT + CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +++D S PCG+++F+++P+ T+ LPQ +C L+ITLPT+
Sbjct: 939 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLATPPPMVEGEGLASRLVEMGPSGAQFLGPVIVEIPHFGSMRSKERELIVLRSENGENWKEHQYDCRVEELTELLNGMDEELDSAEELEKKRICRIVTKDFPQYFAVVSRIKQESNQIGPEGGVLKSTTVPRVQASFPEGALTKRIRVGLQAQPVPDDLVKKVIGNRATFSPIVTVEPRRRKFHKPITMTIPIPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFVNDCVSFTTNVSARFWLGDCHQIPETVSLATQLYRELICVPYMAKFVVFAKMNDPVEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLIFNFYAFKENRLPFSVKVRDHSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPTQ 1413
BLAST of Ankyrin-2 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 801.586 bits (2069), Expect = 0.000e+0 Identity = 410/796 (51.51%), Postives = 569/796 (71.48%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH---AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
M E D L++++ ++LRAARSGN+EK ++L+ + ++ N NGLNA+HLA+KEG+ E+V LI+ G VD +T+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + + +++ TRDGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L +GAS + T ++ E ALH+AAR Q E + LL + A A+A+++QTPLHI+ R+G IV+QLL GA P+ T YT LH++++EG +++ +LLEH TKKGFTPLH+A+KYG+++V + LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G P+HL + G+ +++ LLL +A+VN ++GLT LHLAA+++R + E L A I T+M YT LH A H+G I+ V LLQ VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT
Sbjct: 1 MAVEDGDCLSDQSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQN-GAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVK-LLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVT 793 HSP 2 Score: 442.58 bits (1137), Expect = 2.571e-127 Identity = 234/620 (37.74%), Postives = 356/620 (57.42%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T P + + E LA R++ + S GP+++EIPH ++R ERE++VL+S+NG +WKEH + + L + E + + E + RI RI+T PQYF+++SR+KQ+ IG EGG + S+ +VQA FPEGAL K+I++ LQ + +L++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ SLRLLCSI+G +P WEDITGT+PLT + CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +++D S PCG+++F+++P+ T+ LPQ +C L+ITLPT+ + + DE D + P + C ++++ + VA +G W +L L +EI +I +++ + ++++ L W+ K+ + L L I R DIV
Sbjct: 919 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLATPPPMVEGEGLASRLVEMGPSGAQFLGPVIVEIPHFGSMRSKERELIVLRSENGENWKEHQYDCRVEELTELLNGMDEELDSAEELEKKRICRIVTKDFPQYFAVVSRIKQESNQIGPEGGVLKSTTVPRVQASFPEGALTKRIRVGLQAQPVPDDLVKKVIGNRATFSPIVTVEPRRRKFHKPITMTIPIPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFVNDCVSFTTNVSARFWLGDCHQIPETVSLATQLYRELICVPYMAKFVVFAKMNDPVEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLIFNFYAFKENRLPFSVKVRDHSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPTQKKETESDQDDENEKVDRRQNFVSLALRKRYSYLTEPGMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLTAQSFMLLKKWVVRDG---KNATTDALTNVLTKINRIDIV 1517
BLAST of Ankyrin-2 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 801.971 bits (2070), Expect = 0.000e+0 Identity = 407/804 (50.62%), Postives = 571/804 (71.02%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 2482
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL + NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH+AA+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T+LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL V
Sbjct: 1 MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVV 801 HSP 2 Score: 433.721 bits (1114), Expect = 2.487e-124 Identity = 233/613 (38.01%), Postives = 351/613 (57.26%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQ-TSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP K +K + + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 948 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKAEKA--DRRQSFASLALRKRYSYLTEPSMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1537
BLAST of Ankyrin-2 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0 Identity = 407/804 (50.62%), Postives = 571/804 (71.02%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 2482
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL + NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH+AA+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T+LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL V
Sbjct: 1 MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVV 801 HSP 2 Score: 433.335 bits (1113), Expect = 3.602e-124 Identity = 233/613 (38.01%), Postives = 351/613 (57.26%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQ-TSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP K +K + + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 945 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKAEKA--DRRQSFASLALRKRYSYLTEPSMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1534
BLAST of Ankyrin-2 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0 Identity = 407/804 (50.62%), Postives = 571/804 (71.02%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 2482
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL + NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH+AA+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T+LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL V
Sbjct: 1 MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVV 801 HSP 2 Score: 433.335 bits (1113), Expect = 3.979e-124 Identity = 233/613 (38.01%), Postives = 351/613 (57.26%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQ-TSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP K +K + + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 966 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKAEKA--DRRQSFASLALRKRYSYLTEPSMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1555
BLAST of Ankyrin-2 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0 Identity = 414/827 (50.06%), Postives = 583/827 (70.50%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKM 2551
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL + NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH+AA+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T+LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL KV T M + + +K ++ PE M
Sbjct: 1 MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL-KVVTEEIMTTTTITEKHKMNVPETM 823 HSP 2 Score: 433.721 bits (1114), Expect = 5.009e-125 Identity = 233/613 (38.01%), Postives = 351/613 (57.26%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQ-TSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP K +K + + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 927 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKAEKA--DRRQSFASLALRKRYSYLTEPSMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1516
BLAST of Ankyrin-2 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0 Identity = 407/804 (50.62%), Postives = 571/804 (71.02%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 2482
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL + NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH+AA+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T+LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL V
Sbjct: 1 MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVV 801 HSP 2 Score: 433.335 bits (1113), Expect = 3.979e-124 Identity = 233/613 (38.01%), Postives = 351/613 (57.26%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQ-TSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP K +K + + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 966 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKAEKA--DRRQSFASLALRKRYSYLTEPSMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1555
BLAST of Ankyrin-2 vs. UniProt/SwissProt
Match: sp|Q12955|ANK3_HUMAN (Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3) HSP 1 Score: 805.053 bits (2078), Expect = 0.000e+0 Identity = 402/775 (51.87%), Postives = 562/775 (72.52%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VVK LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D+N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH++A+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL
Sbjct: 44 SYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-NLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815 HSP 2 Score: 431.409 bits (1108), Expect = 8.325e-122 Identity = 208/501 (41.52%), Postives = 307/501 (61.28%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDE 4317
W + LD+V L+ P+ +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E + RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + +++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +A+ LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP + + DE
Sbjct: 965 WAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKETESDQDDE 1450
BLAST of Ankyrin-2 vs. UniProt/SwissProt
Match: sp|G5E8K5|ANK3_MOUSE (Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1) HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0 Identity = 407/804 (50.62%), Postives = 571/804 (71.02%), Query Frame = 2
Query: 107 MVEETKDSLTEKAH------------AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 2482
M EE K+ + AH ++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL + NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH+AA+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T+LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL V
Sbjct: 1 MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVV 801 HSP 2 Score: 433.335 bits (1113), Expect = 2.783e-123 Identity = 233/613 (38.01%), Postives = 351/613 (57.26%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQ-TSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSN-------DLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEE-DKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T +LRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +I+D S PCG+++F+++P+ T+ LPQ +C L+ITLP K +K + + F++ + P + C ++++ + VA +G W +L L +EI +I +++ ++++ L W+T K+ + L L I R DIV
Sbjct: 966 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLPAHKKAEKA--DRRQSFASLALRKRYSYLTEPSMSPQSPCE---RTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDG---KNATTDALTSVLTKINRIDIV 1555
BLAST of Ankyrin-2 vs. UniProt/SwissProt
Match: sp|O70511|ANK3_RAT (Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE=1 SV=3) HSP 1 Score: 795.808 bits (2054), Expect = 0.000e+0 Identity = 401/786 (51.02%), Postives = 562/786 (71.50%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSA--------SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 2482
++LRAAR+G++EK ++++ + ++ N NGLNA+HLA+KEG+ EVV L++ +VD AT+KGNT+LHIASLAG+ EVV +L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LL+ GA+Q++ T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ TRDGL+P+HC ARSG E ++ +LL+ A I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+VLL N NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG IV+ L+ +GAS + T ++ E ALH+AAR+ Q E + L+ A A+A+++QTPLHI+ R+G IV+QLL GA PN T YT LH++A+EG +++ LL+H TKKGFTPLH+A+KYG+++VA LLL +P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ L++ GA+ NA +++G +HL + G+ +++ LLL NA+VN ++GLT LHLAA+++R ++ E L+ A + +T+MGYT LH H+G I+ V LLQ + VNA+T G T LH AAQQGH I+ +LL N N G TAL +A++ Y+++ +TL V
Sbjct: 44 SYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVR-YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVA-SLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVV 826 HSP 2 Score: 431.024 bits (1107), Expect = 7.301e-122 Identity = 208/488 (42.62%), Postives = 301/488 (61.68%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTS-SLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP 4278
W + LD+V L+ PV +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E LA R++ + + GP+++EIPH ++R ERE++VL+S+NG +WKEH + + + L + E + + E RI RIIT PQYF+++SR+KQ+ IG EGG ++S+ VQA FPEGAL K+I++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S S Y T+ SLRLLCSI+G +P WEDITGT+PLT CVSFTT +SAR WL DC++ E V +AS LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T +QL F+ENRL F +++D S PCG+++F+++P+ T+ LPQ +C L+ITLP
Sbjct: 973 WAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLSELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKVRDTSQEPCGRLSFLKEPKT---------------TKGLPQTAVCNLNITLP 1445
BLAST of Ankyrin-2 vs. UniProt/SwissProt
Match: sp|Q01484|ANK2_HUMAN (Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4) HSP 1 Score: 783.867 bits (2023), Expect = 0.000e+0 Identity = 420/811 (51.79%), Postives = 570/811 (70.28%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSA--------SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ I + N NGLNA+HLAAKEG+ +VQ L+ G SVD AT+KGNT+LHIASLAG+ EVV +L++ ANIN +SQNGFTPLYMAAQENH+DVVK LLE GANQ+ T+DGFTPLAVALQQG+++ V ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+KLL+ + +++ TRDGL+P+HCAARSG + ++ +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS T ++ E ALH+AAR Q E + LL + A +ARARE QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ +++ +LLE TKKGFTPLH+A+KYG + VA+ LLL + +S G +GLTPLHVA +Y++ ++ LLL+ A+ + KNGYTPLH+ AKKN +++ L++ GA N +++G TPLHL S G+ +++ LLLD A+++ ++GLT+LHLAA++++ ++ + L K AD T++GYT L A H+G ++ V LL++ +VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 34 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN-GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAK-LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE 841 HSP 2 Score: 432.18 bits (1110), Expect = 3.634e-122 Identity = 229/571 (40.11%), Postives = 334/571 (58.49%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRII-------------HLNASTQSLD--------------------GPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGD 4431
W E LD+V L P+ +GFL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ T+P + + E LA R+I HL + L+ GP+++EIPH AALR ERE+VVL+S+NG SWKEH +T+ + + L + E + + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ + L++K GN SPIVTLEPRRRKFH+ IT+T+P+P S + +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V AS +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL + +++D + PCG+++FM++P+ T+ L + IC L+ITLP T++ ++ ++E D+ +D+ E +++KS L + EV + D
Sbjct: 949 WGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKS---------------TRGLVHQAICNLNITLPIY-TKESESDQEQEEEIDMTSEKNDETESTETSVLKSHL-VNEVPVLASPD 1502
BLAST of Ankyrin-2 vs. UniProt/SwissProt
Match: sp|Q8C8R3|ANK2_MOUSE (Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV=2) HSP 1 Score: 781.556 bits (2017), Expect = 0.000e+0 Identity = 419/811 (51.66%), Postives = 569/811 (70.16%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSA--------SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ I + N NGLNA+HLAAKEG+ +VQ L+ G SVD AT+KGNT+LHIASLAG+ EVV +L++ ANIN +SQNGFTPLYMAAQENH+DVVK LLE GANQ+ T+DGFTPLAVALQQG+++ V ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M+KLL+ + +++ TRDGL+P+HCAARSG + ++ +LLE A + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS T ++ E ALH+AAR Q E + LL + A +ARARE QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ +++ +LLE TKKGFTPLH+A+KYG + VA+ LLL + +S G +GLTPLHVA +Y++ ++ LLL+ A+ + KNGYTPLH+ AKKN +++ L++ GA N +++G TPLHL S G+ +++ LLLD A+++ ++GLT+LHLAA++++ ++ + L K AD T++GYT L A H+G ++ V LL++ +VNA+T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 34 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRN-GALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAK-LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTE 841 HSP 2 Score: 448.358 bits (1152), Expect = 2.612e-127 Identity = 216/487 (44.35%), Postives = 307/487 (63.04%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP 4278
W E LD+V L P+ +GFL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ T+P + + E LA R+I + S GP+++EIPH AALR ERE+VVL+S+NG SWKEH +T+ + + L + E + + E + RI RIIT PQYF+++SR+KQD IG EGG ++S+V +QVQAVFPEGAL K+I++ LQ + L++K GN SPIVTLEPRRRKFH+ IT+T+P+P S + +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E V AS +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE +++ GN++P+T S + F+ENRL + +++D + PCG+++FM++P+ T+ L + IC L+ITLP
Sbjct: 949 WGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKS---------------TRGLVHQAICNLNITLP 1420
BLAST of Ankyrin-2 vs. TrEMBL
Match: G7Y8Z7 (Ankyrin-2 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_103060 PE=4 SV=1) HSP 1 Score: 889.026 bits (2296), Expect = 0.000e+0 Identity = 444/829 (53.56%), Postives = 605/829 (72.98%), Query Frame = 2
Query: 113 EETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLI----DRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNF--DVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKK-----LILDQPEKMIDHSM 2566
++T+ +LTE FLRAAR+G++ KV E L A + ++SN GL A+HLA+KEG ++V+ LI G D T+KGNT+LHIASLAG L+VV +LL++ AN+N +S GFTPLYMAAQENHL VV +LL+ GANQA+TT+DGFTPLAVALQQG+++VV +LL+ DSRS+ +PALHIAA+KDDVN+ +LL+ + + NV+HQ+ GFTPLHIAAHY NVNVA+ L+++ ADVN+ AKNNITPLH+A+KWG+ EM++LLI+ A V+ TRDGL+P+HCAARSG + +L++ GA+ K++NGLT L M QG+ EV LI +G V+ T D LT LHVA+HCGN A +LL+N C+ NARALNGFTPLHIACKK + ++VELL++Y A I+ TE+GL+PLH+AAF+GS EIV +LL+NG + Q TM+ E ALHLAARN Q E + L+ H A +A+A+++QTPLH+AV G+ +V LL+AGA+PN+ T+D YTA+HIAAKEG E+ RLLL+ P A+TKKGF PLH+A+K GRV+ ARQLL + N+ G + LTPLH+A +YNH ++ELLLD+ A +C NGYTPLH+ AK+N +++ LL+ ++ + NA+S+ GFTPLHL + G+ +++ LLL AD NHQ++NGLT LHLAA++N I LL T AD+S T+ GY++LHTA HFGQ++ V+ LL+ D+N T +G T LHLA QQGH IV LLL+ D N +N+QGLT +A++QH++ I + L VTT ++S EE++ L+L QP+ M +H +
Sbjct: 11 DKTQPNLTEMDQNFLRAARAGSLAKVVELLNAGVNINLSNPIGLTALHLASKEGYVDIVEELIRRGADFDAPTKKGNTALHIASLAGHLQVVQILLDAGANVNRQSVIGFTPLYMAAQENHLAVVDLLLKRGANQALTTEDGFTPLAVALQQGHERVVALLLERDSRSRGGMPALHIAARKDDVNSVALLLNNPEVNVNHQAQHGFTPLHIAAHYGNVNVARPLLDRGADVNYQAKNNITPLHIASKWGRIEMVRLLIAAGALVDCRTRDGLTPLHCAARSGHAELASLLIDAGANPSAKTRNGLTPLHMGAQGNNEEVAHVLILRGASVEDKTGDLLTPLHVASHCGNREVARILLENRCDANARALNGFTPLHIACKKQKIRVVELLLRYGAQIDMITESGLSPLHVAAFIGSPEIVQLLLQNGTYVDQATMRSETALHLAARNRQVEVARALIFH-GATVDAKAKDDQTPLHMAVLTGHVEMVVLLLSAGANPNLTTRDAYTAMHIAAKEGHQEVIRLLLDAHADPVARTKKGFIPLHLAAKRGRVKAARQLLQIQPKSVNTAGQNNLTPLHLAAHYNHLRLVELLLDSGAEADCRAGNGYTPLHIAAKQNHLDIATLLLAHEAEQSQSGNAESRGGFTPLHLAAQEGHTDMVSLLLQHGADPNHQSKNGLTPLHLAAQENHVPIARVLLSTGADVSLVTRAGYSSLHTACHFGQLEMVRFLLEVTHATDINLPTQMGFTPLHLATQQGHSQIVSLLLEMGADGNLRNQQGLTPAHIARRQHFVTIFDILKTVTTT--VVSWEEEQEELDGTLLLQQPDFMREHPL 836 HSP 2 Score: 559.296 bits (1440), Expect = 1.092e-163 Identity = 278/662 (41.99%), Postives = 410/662 (61.93%), Query Frame = 1
Query: 2782 ANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANR----SIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQK------GLNNIDEEFSNDLIFNPD---------DKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDIS-IVDESERKFAETIINGGDP 4707
+ ++ T DWE+E+D+V ++++P+ GFL+SFIVDA+GG++QA R D+R ++P N+V GP RI+C L E + P + D + ACR++ + PI+LEIPH A L + REV+VL+SDNG +WKEH D AVQD + + + + + + + RI+T LPQYF+LI+R++Q++ IG EGGT+ S+V ++VQ VFP GAL+KKI++ LQ+H I + L+ + G V +SPIVT+EPRRRKFH+ ITL +PLP S A + +V + SLRLLCSISG +PTVWEDITG+SPL+ VSFTTT+SAR+WL+DC T E+V++AS +Y ES VP+IG+F+V+ RR + EE Q+RCLC+TDD KTLE QE F L+++GP VEVL++H +W+E++GN++P+ S+EQL L + F ENRL+ R+KDL+ P GK+AF PR ++ L +PQK I L+ +P + +IDE + +PD +K I + EL++ VA VG DW +L LG+ EE I T+ ++AY AL++W + +S GN+L L IGR D+V+ C+ ++S + ER+ A +++ +P
Sbjct: 932 SRMFGETIQSGGDWELEVDNVNIVRKPISTGFLVSFIVDARGGMLQAQRCSDLRFFIPPNAVSGPIRIVCRLLHPERVGSPPPINDGDGFACRVLEMGPVGVRFSAPIVLEIPHYAFLTEKNREVIVLRSDNGETWKEHPLDANDQAVQDTVNGYFDYVDSADELRKRNVHRILTYDLPQYFALITRVRQELILIGPEGGTLTSNVVSEVQVVFPPGALQKKIRVGLQVHCIDQELVSRLLGARVLVSPIVTIEPRRRKFHKPITLKMPLPKSSTATGAGGLAAHSSVDSPSLRLLCSISGGTSPTVWEDITGSSPLSASKNTVSFTTTVSARLWLVDCPNTTEVVELASRVYHESLSVPYIGRFIVYGRRHHPEEAQLRCLCLTDDPIAKTLEQQEGFHLLATGPQVEVLDDHPHWIETAGNLVPVAKSEEQLQLNVRAFHENRLNMLVRVKDLTQPAVGKLAFTLHPR--AVLQSLG----------IPQKRITVLEAHVPDGLSGSISGAVLKTTDIDEVTELSMSQHPDGLVNGFGVPSQKRDFSEVIGRLELDLSNVANSVGSDWPRLATALGITAEEQKMISSSYRTDSERAYAALIIW--QDRAGIESTSGNKLAQVLHQIGRADVVQACMSNVSPVTSPDERRIALRVLDSTEP 1579
BLAST of Ankyrin-2 vs. TrEMBL
Match: A0A4S2MA63 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002880 PE=4 SV=1) HSP 1 Score: 888.256 bits (2294), Expect = 0.000e+0 Identity = 444/829 (53.56%), Postives = 605/829 (72.98%), Query Frame = 2
Query: 113 EETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLI----DRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNF--DVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKK-----LILDQPEKMIDHSM 2566
++T+ +LTE FLRAAR+G++ KV E L A + ++SN GL A+HLA+KEG ++V+ LI G D T+KGNT+LHIASLAG L+VV +LL++ AN+N +S GFTPLYMAAQENHL VV +LL+ GANQA+TT+DGFTPLAVALQQG+++VV +LL+ DSRS+ +PALHIAA+KDDVN+ +LL+ + + NV+HQ+ GFTPLHIAAHY NVNVA+ L+++ ADVN+ AKNNITPLH+A+KWG+ EM++LLI+ A V+ TRDGL+P+HCAARSG + +L++ GA+ K++NGLT L M QG+ EV LI +G V+ T D LT LHVA+HCGN A +LL+N C+ NARALNGFTPLHIACKK + ++VELL++Y A I+ TE+GL+PLH+AAF+GS EIV +LL+NG + Q TM+ E ALHLAARN Q E + L+ H A +A+A+++QTPLH+AV G+ +V LL+AGA+PN+ T+D YTA+HIAAKEG E+ RLLL+ P A+TKKGF PLH+A+K GRV+ ARQLL + N+ G + LTPLH+A +YNH ++ELLLD+ A +C NGYTPLH+ AK+N +++ LL+ ++ + NA+S+ GFTPLHL + G+ +++ LLL AD NHQ++NGLT LHLAA++N I LL T AD+S T+ GY++LHTA HFGQ++ V+ LL+ D+N T +G T LHLA QQGH IV LLL+ D N +N+QGLT +A++QH++ I + L VTT ++S EE++ L+L QP+ M +H +
Sbjct: 11 DKTQPNLTEMDQNFLRAARAGSLAKVVELLNAGVNINLSNPIGLTALHLASKEGYVDIVEELIRRGADFDAPTKKGNTALHIASLAGHLQVVQILLDAGANVNRQSVIGFTPLYMAAQENHLAVVDLLLKRGANQALTTEDGFTPLAVALQQGHERVVALLLERDSRSRGGMPALHIAARKDDVNSVALLLNNPEVNVNHQAQHGFTPLHIAAHYGNVNVARPLLDRGADVNYQAKNNITPLHIASKWGRIEMVRLLIAAGALVDCRTRDGLTPLHCAARSGHAELASLLIDAGANPSAKTRNGLTPLHMGAQGNNEEVAHVLILRGASVEDKTGDLLTPLHVASHCGNREVARILLENRCDANARALNGFTPLHIACKKQKIRVVELLLRYGAQIDMITESGLSPLHVAAFIGSPEIVQLLLQNGTYVDQATMRSETALHLAARNRQVEVARALIFH-GATVDAKAKDDQTPLHMAVLTGHVEMVVLLLSAGANPNLTTRDAYTAMHIAAKEGHQEVIRLLLDAHADPVARTKKGFIPLHLAAKRGRVKAARQLLQIQPKSVNTAGQNNLTPLHLAAHYNHLRLVELLLDSGAEADCRAGNGYTPLHIAAKQNHLDIATLLLAHEAEQSQSGNAESRGGFTPLHLAAQEGHTDMVSLLLQHGADPNHQSKNGLTPLHLAAQENHVPIARVLLSTGADVSLVTRAGYSSLHTACHFGQLEMVRFLLEITHATDINLPTQMGFTPLHLATQQGHSQIVSLLLEMGADGNLRNQQGLTPAHIARRQHFVTIFDILKTVTTT--VVSWEEEQEELDGTLLLQQPDFMREHPL 836 HSP 2 Score: 558.14 bits (1437), Expect = 2.407e-163 Identity = 280/667 (41.98%), Postives = 412/667 (61.77%), Query Frame = 1
Query: 2782 ANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANR----SIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLN-----------NIDEEFSNDLIFNPD---------DKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDIS-IVDESERKFAETIINGGDP 4707
+ ++ T DWE+E+D+V ++++P+ GFL+SFIVDA+GG++QA R D+R ++P N+V GP RI+C L E + P + D + ACR++ + PI+LEIPH A L + REV+VL+SDNG +WKEH D AVQD + + + + + + + RI+T LPQYF+LI+R+KQ++ IG EGGT+ S+V ++VQ VFP GAL+KKI++ LQ+H I + L+ + G V +SPIVT+EPRRRKFH+ ITL +PLP + A + +V + SLRLLCSISG +PTVWEDITG+SPL+ VSFTTT+SAR+WL+DC T E+V++AS +Y ES VP+IG+F+V+ RR + EE Q+RCLC+TDD KTLE QE F L+++GP VEVL++H +W+E++GN++P+ S+EQL L + F ENRL+ R+KDL+ P GK+AF PR ++ L +PQK I L+ +P GL+ +IDE + +PD +K I + EL++ VA VG DW +L LG+ EE I T+ ++AY AL++W + +S GN+L L IGR D+V+ C+ ++S + ER+ A +++ +P
Sbjct: 946 SRMFGETIQSGGDWELEVDNVNIVRKPISTGFLVSFIVDARGGMLQAQRCSDLRFFIPPNAVSGPIRIVCRLLHPERVGSPPPINDGDGFACRVLEMGPVGVRFSAPIVLEIPHYAFLTEKNREVIVLRSDNGETWKEHPLDANDQAVQDTVNGYFDYVDSADELRKRSVHRILTYDLPQYFALITRVKQELILIGPEGGTLTSNVVSEVQVVFPPGALQKKIRVGLQVHCIDQELVSRLLGARVLVSPIVTIEPRRRKFHKPITLKMPLPKSNTATGAGGLAAHSSVDSPSLRLLCSISGGTSPTVWEDITGSSPLSASKNMVSFTTTVSARLWLVDCPNTTEVVELASRVYHESLSVPYIGRFIVYGRRHHPEEAQLRCLCLTDDPIAKTLEQQEGFHLLATGPQVEVLDDHPHWIETAGNLVPVAKSEEQLQLNVRAFHENRLNMLVRVKDLTQPAVGKLAFTLHPR--AVLQSLG----------IPQKRITVLEAHVP-----DGLSGSISGAVLRTTDIDEVTELSMSQHPDGLVNGFGVPSQKGDFSEVIGRLELDLSNVANSVGSDWPRLATVLGLSAEEQKMISSSYRTDSERAYAALIIW--QDRAGIESTTGNKLAQVLHQIGRADVVQACMSNVSPVTSPDERRIALRVLDSTEP 1593
BLAST of Ankyrin-2 vs. TrEMBL
Match: A0A4S2M3X3 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002880 PE=4 SV=1) HSP 1 Score: 888.256 bits (2294), Expect = 0.000e+0 Identity = 444/829 (53.56%), Postives = 605/829 (72.98%), Query Frame = 2
Query: 113 EETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLI----DRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNF--DVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKK-----LILDQPEKMIDHSM 2566
++T+ +LTE FLRAAR+G++ KV E L A + ++SN GL A+HLA+KEG ++V+ LI G D T+KGNT+LHIASLAG L+VV +LL++ AN+N +S GFTPLYMAAQENHL VV +LL+ GANQA+TT+DGFTPLAVALQQG+++VV +LL+ DSRS+ +PALHIAA+KDDVN+ +LL+ + + NV+HQ+ GFTPLHIAAHY NVNVA+ L+++ ADVN+ AKNNITPLH+A+KWG+ EM++LLI+ A V+ TRDGL+P+HCAARSG + +L++ GA+ K++NGLT L M QG+ EV LI +G V+ T D LT LHVA+HCGN A +LL+N C+ NARALNGFTPLHIACKK + ++VELL++Y A I+ TE+GL+PLH+AAF+GS EIV +LL+NG + Q TM+ E ALHLAARN Q E + L+ H A +A+A+++QTPLH+AV G+ +V LL+AGA+PN+ T+D YTA+HIAAKEG E+ RLLL+ P A+TKKGF PLH+A+K GRV+ ARQLL + N+ G + LTPLH+A +YNH ++ELLLD+ A +C NGYTPLH+ AK+N +++ LL+ ++ + NA+S+ GFTPLHL + G+ +++ LLL AD NHQ++NGLT LHLAA++N I LL T AD+S T+ GY++LHTA HFGQ++ V+ LL+ D+N T +G T LHLA QQGH IV LLL+ D N +N+QGLT +A++QH++ I + L VTT ++S EE++ L+L QP+ M +H +
Sbjct: 11 DKTQPNLTEMDQNFLRAARAGSLAKVVELLNAGVNINLSNPIGLTALHLASKEGYVDIVEELIRRGADFDAPTKKGNTALHIASLAGHLQVVQILLDAGANVNRQSVIGFTPLYMAAQENHLAVVDLLLKRGANQALTTEDGFTPLAVALQQGHERVVALLLERDSRSRGGMPALHIAARKDDVNSVALLLNNPEVNVNHQAQHGFTPLHIAAHYGNVNVARPLLDRGADVNYQAKNNITPLHIASKWGRIEMVRLLIAAGALVDCRTRDGLTPLHCAARSGHAELASLLIDAGANPSAKTRNGLTPLHMGAQGNNEEVAHVLILRGASVEDKTGDLLTPLHVASHCGNREVARILLENRCDANARALNGFTPLHIACKKQKIRVVELLLRYGAQIDMITESGLSPLHVAAFIGSPEIVQLLLQNGTYVDQATMRSETALHLAARNRQVEVARALIFH-GATVDAKAKDDQTPLHMAVLTGHVEMVVLLLSAGANPNLTTRDAYTAMHIAAKEGHQEVIRLLLDAHADPVARTKKGFIPLHLAAKRGRVKAARQLLQIQPKSVNTAGQNNLTPLHLAAHYNHLRLVELLLDSGAEADCRAGNGYTPLHIAAKQNHLDIATLLLAHEAEQSQSGNAESRGGFTPLHLAAQEGHTDMVSLLLQHGADPNHQSKNGLTPLHLAAQENHVPIARVLLSTGADVSLVTRAGYSSLHTACHFGQLEMVRFLLEITHATDINLPTQMGFTPLHLATQQGHSQIVSLLLEMGADGNLRNQQGLTPAHIARRQHFVTIFDILKTVTTT--VVSWEEEQEELDGTLLLQQPDFMREHPL 836 HSP 2 Score: 559.296 bits (1440), Expect = 5.090e-163 Identity = 280/667 (41.98%), Postives = 412/667 (61.77%), Query Frame = 1
Query: 2782 ANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANR----SIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLN-----------NIDEEFSNDLIFNPD---------DKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDIS-IVDESERKFAETIINGGDP 4707
+ ++ T DWE+E+D+V ++++P+ GFL+SFIVDA+GG++QA R D+R ++P N+V GP RI+C L E + P + D + ACR++ + PI+LEIPH A L + REV+VL+SDNG +WKEH D AVQD + + + + + + + RI+T LPQYF+LI+R+KQ++ IG EGGT+ S+V ++VQ VFP GAL+KKI++ LQ+H I + L+ + G V +SPIVT+EPRRRKFH+ ITL +PLP + A + +V + SLRLLCSISG +PTVWEDITG+SPL+ VSFTTT+SAR+WL+DC T E+V++AS +Y ES VP+IG+F+V+ RR + EE Q+RCLC+TDD KTLE QE F L+++GP VEVL++H +W+E++GN++P+ S+EQL L + F ENRL+ R+KDL+ P GK+AF PR ++ L +PQK I L+ +P GL+ +IDE + +PD +K I + EL++ VA VG DW +L LG+ EE I T+ ++AY AL++W + +S GN+L L IGR D+V+ C+ ++S + ER+ A +++ +P
Sbjct: 932 SRMFGETIQSGGDWELEVDNVNIVRKPISTGFLVSFIVDARGGMLQAQRCSDLRFFIPPNAVSGPIRIVCRLLHPERVGSPPPINDGDGFACRVLEMGPVGVRFSAPIVLEIPHYAFLTEKNREVIVLRSDNGETWKEHPLDANDQAVQDTVNGYFDYVDSADELRKRSVHRILTYDLPQYFALITRVKQELILIGPEGGTLTSNVVSEVQVVFPPGALQKKIRVGLQVHCIDQELVSRLLGARVLVSPIVTIEPRRRKFHKPITLKMPLPKSNTATGAGGLAAHSSVDSPSLRLLCSISGGTSPTVWEDITGSSPLSASKNMVSFTTTVSARLWLVDCPNTTEVVELASRVYHESLSVPYIGRFIVYGRRHHPEEAQLRCLCLTDDPIAKTLEQQEGFHLLATGPQVEVLDDHPHWIETAGNLVPVAKSEEQLQLNVRAFHENRLNMLVRVKDLTQPAVGKLAFTLHPR--AVLQSLG----------IPQKRITVLEAHVP-----DGLSGSISGAVLRTTDIDEVTELSMSQHPDGLVNGFGVPSQKGDFSEVIGRLELDLSNVANSVGSDWPRLATVLGLSAEEQKMISSSYRTDSERAYAALIIW--QDRAGIESTTGNKLAQVLHQIGRADVVQACMSNVSPVTSPDERRIALRVLDSTEP 1579
BLAST of Ankyrin-2 vs. TrEMBL
Match: A0A4S2M3V6 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002880 PE=4 SV=1) HSP 1 Score: 887.871 bits (2293), Expect = 0.000e+0 Identity = 444/829 (53.56%), Postives = 605/829 (72.98%), Query Frame = 2
Query: 113 EETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLI----DRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNF--DVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKK-----LILDQPEKMIDHSM 2566
++T+ +LTE FLRAAR+G++ KV E L A + ++SN GL A+HLA+KEG ++V+ LI G D T+KGNT+LHIASLAG L+VV +LL++ AN+N +S GFTPLYMAAQENHL VV +LL+ GANQA+TT+DGFTPLAVALQQG+++VV +LL+ DSRS+ +PALHIAA+KDDVN+ +LL+ + + NV+HQ+ GFTPLHIAAHY NVNVA+ L+++ ADVN+ AKNNITPLH+A+KWG+ EM++LLI+ A V+ TRDGL+P+HCAARSG + +L++ GA+ K++NGLT L M QG+ EV LI +G V+ T D LT LHVA+HCGN A +LL+N C+ NARALNGFTPLHIACKK + ++VELL++Y A I+ TE+GL+PLH+AAF+GS EIV +LL+NG + Q TM+ E ALHLAARN Q E + L+ H A +A+A+++QTPLH+AV G+ +V LL+AGA+PN+ T+D YTA+HIAAKEG E+ RLLL+ P A+TKKGF PLH+A+K GRV+ ARQLL + N+ G + LTPLH+A +YNH ++ELLLD+ A +C NGYTPLH+ AK+N +++ LL+ ++ + NA+S+ GFTPLHL + G+ +++ LLL AD NHQ++NGLT LHLAA++N I LL T AD+S T+ GY++LHTA HFGQ++ V+ LL+ D+N T +G T LHLA QQGH IV LLL+ D N +N+QGLT +A++QH++ I + L VTT ++S EE++ L+L QP+ M +H +
Sbjct: 11 DKTQPNLTEMDQNFLRAARAGSLAKVVELLNAGVNINLSNPIGLTALHLASKEGYVDIVEELIRRGADFDAPTKKGNTALHIASLAGHLQVVQILLDAGANVNRQSVIGFTPLYMAAQENHLAVVDLLLKRGANQALTTEDGFTPLAVALQQGHERVVALLLERDSRSRGGMPALHIAARKDDVNSVALLLNNPEVNVNHQAQHGFTPLHIAAHYGNVNVARPLLDRGADVNYQAKNNITPLHIASKWGRIEMVRLLIAAGALVDCRTRDGLTPLHCAARSGHAELASLLIDAGANPSAKTRNGLTPLHMGAQGNNEEVAHVLILRGASVEDKTGDLLTPLHVASHCGNREVARILLENRCDANARALNGFTPLHIACKKQKIRVVELLLRYGAQIDMITESGLSPLHVAAFIGSPEIVQLLLQNGTYVDQATMRSETALHLAARNRQVEVARALIFH-GATVDAKAKDDQTPLHMAVLTGHVEMVVLLLSAGANPNLTTRDAYTAMHIAAKEGHQEVIRLLLDAHADPVARTKKGFIPLHLAAKRGRVKAARQLLQIQPKSVNTAGQNNLTPLHLAAHYNHLRLVELLLDSGAEADCRAGNGYTPLHIAAKQNHLDIATLLLAHEAEQSQSGNAESRGGFTPLHLAAQEGHTDMVSLLLQHGADPNHQSKNGLTPLHLAAQENHVPIARVLLSTGADVSLVTRAGYSSLHTACHFGQLEMVRFLLEITHATDINLPTQMGFTPLHLATQQGHSQIVSLLLEMGADGNLRNQQGLTPAHIARRQHFVTIFDILKTVTTT--VVSWEEEQEELDGTLLLQQPDFMREHPL 836 HSP 2 Score: 558.14 bits (1437), Expect = 1.139e-163 Identity = 280/667 (41.98%), Postives = 412/667 (61.77%), Query Frame = 1
Query: 2782 ANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANR----SIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLN-----------NIDEEFSNDLIFNPD---------DKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDIS-IVDESERKFAETIINGGDP 4707
+ ++ T DWE+E+D+V ++++P+ GFL+SFIVDA+GG++QA R D+R ++P N+V GP RI+C L E + P + D + ACR++ + PI+LEIPH A L + REV+VL+SDNG +WKEH D AVQD + + + + + + + RI+T LPQYF+LI+R+KQ++ IG EGGT+ S+V ++VQ VFP GAL+KKI++ LQ+H I + L+ + G V +SPIVT+EPRRRKFH+ ITL +PLP + A + +V + SLRLLCSISG +PTVWEDITG+SPL+ VSFTTT+SAR+WL+DC T E+V++AS +Y ES VP+IG+F+V+ RR + EE Q+RCLC+TDD KTLE QE F L+++GP VEVL++H +W+E++GN++P+ S+EQL L + F ENRL+ R+KDL+ P GK+AF PR ++ L +PQK I L+ +P GL+ +IDE + +PD +K I + EL++ VA VG DW +L LG+ EE I T+ ++AY AL++W + +S GN+L L IGR D+V+ C+ ++S + ER+ A +++ +P
Sbjct: 932 SRMFGETIQSGGDWELEVDNVNIVRKPISTGFLVSFIVDARGGMLQAQRCSDLRFFIPPNAVSGPIRIVCRLLHPERVGSPPPINDGDGFACRVLEMGPVGVRFSAPIVLEIPHYAFLTEKNREVIVLRSDNGETWKEHPLDANDQAVQDTVNGYFDYVDSADELRKRSVHRILTYDLPQYFALITRVKQELILIGPEGGTLTSNVVSEVQVVFPPGALQKKIRVGLQVHCIDQELVSRLLGARVLVSPIVTIEPRRRKFHKPITLKMPLPKSNTATGAGGLAAHSSVDSPSLRLLCSISGGTSPTVWEDITGSSPLSASKNMVSFTTTVSARLWLVDCPNTTEVVELASRVYHESLSVPYIGRFIVYGRRHHPEEAQLRCLCLTDDPIAKTLEQQEGFHLLATGPQVEVLDDHPHWIETAGNLVPVAKSEEQLQLNVRAFHENRLNMLVRVKDLTQPAVGKLAFTLHPR--AVLQSLG----------IPQKRITVLEAHVP-----DGLSGSISGAVLRTTDIDEVTELSMSQHPDGLVNGFGVPSQKGDFSEVIGRLELDLSNVANSVGSDWPRLATVLGLSAEEQKMISSSYRTDSERAYAALIIW--QDRAGIESTTGNKLAQVLHQIGRADVVQACMSNVSPVTSPDERRIALRVLDSTEP 1579
BLAST of Ankyrin-2 vs. TrEMBL
Match: A0A4S2M4H4 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002880 PE=4 SV=1) HSP 1 Score: 887.871 bits (2293), Expect = 0.000e+0 Identity = 444/829 (53.56%), Postives = 605/829 (72.98%), Query Frame = 2
Query: 113 EETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLI----DRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNF--DVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKK-----LILDQPEKMIDHSM 2566
++T+ +LTE FLRAAR+G++ KV E L A + ++SN GL A+HLA+KEG ++V+ LI G D T+KGNT+LHIASLAG L+VV +LL++ AN+N +S GFTPLYMAAQENHL VV +LL+ GANQA+TT+DGFTPLAVALQQG+++VV +LL+ DSRS+ +PALHIAA+KDDVN+ +LL+ + + NV+HQ+ GFTPLHIAAHY NVNVA+ L+++ ADVN+ AKNNITPLH+A+KWG+ EM++LLI+ A V+ TRDGL+P+HCAARSG + +L++ GA+ K++NGLT L M QG+ EV LI +G V+ T D LT LHVA+HCGN A +LL+N C+ NARALNGFTPLHIACKK + ++VELL++Y A I+ TE+GL+PLH+AAF+GS EIV +LL+NG + Q TM+ E ALHLAARN Q E + L+ H A +A+A+++QTPLH+AV G+ +V LL+AGA+PN+ T+D YTA+HIAAKEG E+ RLLL+ P A+TKKGF PLH+A+K GRV+ ARQLL + N+ G + LTPLH+A +YNH ++ELLLD+ A +C NGYTPLH+ AK+N +++ LL+ ++ + NA+S+ GFTPLHL + G+ +++ LLL AD NHQ++NGLT LHLAA++N I LL T AD+S T+ GY++LHTA HFGQ++ V+ LL+ D+N T +G T LHLA QQGH IV LLL+ D N +N+QGLT +A++QH++ I + L VTT ++S EE++ L+L QP+ M +H +
Sbjct: 11 DKTQPNLTEMDQNFLRAARAGSLAKVVELLNAGVNINLSNPIGLTALHLASKEGYVDIVEELIRRGADFDAPTKKGNTALHIASLAGHLQVVQILLDAGANVNRQSVIGFTPLYMAAQENHLAVVDLLLKRGANQALTTEDGFTPLAVALQQGHERVVALLLERDSRSRGGMPALHIAARKDDVNSVALLLNNPEVNVNHQAQHGFTPLHIAAHYGNVNVARPLLDRGADVNYQAKNNITPLHIASKWGRIEMVRLLIAAGALVDCRTRDGLTPLHCAARSGHAELASLLIDAGANPSAKTRNGLTPLHMGAQGNNEEVAHVLILRGASVEDKTGDLLTPLHVASHCGNREVARILLENRCDANARALNGFTPLHIACKKQKIRVVELLLRYGAQIDMITESGLSPLHVAAFIGSPEIVQLLLQNGTYVDQATMRSETALHLAARNRQVEVARALIFH-GATVDAKAKDDQTPLHMAVLTGHVEMVVLLLSAGANPNLTTRDAYTAMHIAAKEGHQEVIRLLLDAHADPVARTKKGFIPLHLAAKRGRVKAARQLLQIQPKSVNTAGQNNLTPLHLAAHYNHLRLVELLLDSGAEADCRAGNGYTPLHIAAKQNHLDIATLLLAHEAEQSQSGNAESRGGFTPLHLAAQEGHTDMVSLLLQHGADPNHQSKNGLTPLHLAAQENHVPIARVLLSTGADVSLVTRAGYSSLHTACHFGQLEMVRFLLEITHATDINLPTQMGFTPLHLATQQGHSQIVSLLLEMGADGNLRNQQGLTPAHIARRQHFVTIFDILKTVTTT--VVSWEEEQEELDGTLLLQQPDFMREHPL 836 HSP 2 Score: 557.755 bits (1436), Expect = 1.488e-163 Identity = 280/667 (41.98%), Postives = 412/667 (61.77%), Query Frame = 1
Query: 2782 ANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANR----SIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLN-----------NIDEEFSNDLIFNPD---------DKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDIS-IVDESERKFAETIINGGDP 4707
+ ++ T DWE+E+D+V ++++P+ GFL+SFIVDA+GG++QA R D+R ++P N+V GP RI+C L E + P + D + ACR++ + PI+LEIPH A L + REV+VL+SDNG +WKEH D AVQD + + + + + + + RI+T LPQYF+LI+R+KQ++ IG EGGT+ S+V ++VQ VFP GAL+KKI++ LQ+H I + L+ + G V +SPIVT+EPRRRKFH+ ITL +PLP + A + +V + SLRLLCSISG +PTVWEDITG+SPL+ VSFTTT+SAR+WL+DC T E+V++AS +Y ES VP+IG+F+V+ RR + EE Q+RCLC+TDD KTLE QE F L+++GP VEVL++H +W+E++GN++P+ S+EQL L + F ENRL+ R+KDL+ P GK+AF PR ++ L +PQK I L+ +P GL+ +IDE + +PD +K I + EL++ VA VG DW +L LG+ EE I T+ ++AY AL++W + +S GN+L L IGR D+V+ C+ ++S + ER+ A +++ +P
Sbjct: 932 SRMFGETIQSGGDWELEVDNVNIVRKPISTGFLVSFIVDARGGMLQAQRCSDLRFFIPPNAVSGPIRIVCRLLHPERVGSPPPINDGDGFACRVLEMGPVGVRFSAPIVLEIPHYAFLTEKNREVIVLRSDNGETWKEHPLDANDQAVQDTVNGYFDYVDSADELRKRSVHRILTYDLPQYFALITRVKQELILIGPEGGTLTSNVVSEVQVVFPPGALQKKIRVGLQVHCIDQELVSRLLGARVLVSPIVTIEPRRRKFHKPITLKMPLPKSNTATGAGGLAAHSSVDSPSLRLLCSISGGTSPTVWEDITGSSPLSASKNMVSFTTTVSARLWLVDCPNTTEVVELASRVYHESLSVPYIGRFIVYGRRHHPEEAQLRCLCLTDDPIAKTLEQQEGFHLLATGPQVEVLDDHPHWIETAGNLVPVAKSEEQLQLNVRAFHENRLNMLVRVKDLTQPAVGKLAFTLHPR--AVLQSLG----------IPQKRITVLEAHVP-----DGLSGSISGAVLRTTDIDEVTELSMSQHPDGLVNGFGVPSQKGDFSEVIGRLELDLSNVANSVGSDWPRLATVLGLSAEEQKMISSSYRTDSERAYAALIIW--QDRAGIESTTGNKLAQVLHQIGRADVVQACMSNVSPVTSPDERRIALRVLDSTEP 1579
BLAST of Ankyrin-2 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 796.579 bits (2056), Expect = 0.000e+0 Identity = 408/801 (50.94%), Postives = 567/801 (70.79%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKM 2551
++LRAAR+GN+EK ++L+ + ++ N NGLNA+HLA+KEG+ EVV L++ G SVD AT+KGNT+LHIASLAG+ +VV L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LLE+GA+Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVAAK G M+KLL+ + A +++ T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A + + TE+GLTP+H+AAFMG + IV L +GAS + T ++ E ALH+AAR Q + + LL + A + +A+++QT LHIA R+G IV+ LL GA + T YT LH+A +EG E + LLLEH A TKKGFTPLH+A+KYG+++ A+ LLL + P++ G GLTPLHVA +Y++ + LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA NA +++G +PLHL + G+ +++ LLL NA+VN +NGLT LHLAA+++R + E LL A++ T+ GYT LH A H+G ++ V LL+ +N++T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL +T + +K L+ PE M
Sbjct: 46 SYLRAARAGNLEKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQN-GAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAK-LLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTLRGLTDENLTATPPVSEKHKLNVPETM 843 HSP 2 Score: 403.675 bits (1036), Expect = 4.592e-115 Identity = 212/616 (34.42%), Postives = 336/616 (54.55%), Query Frame = 1
Query: 2851 IQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALG---NLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLP-----NWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
+ P+ +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E L R++ + + GP+++EIPH ++R ERE++VL+SDNG +WKEH D +D L + E + + + RI RI+T PQYF+++SR+KQ+ +G EGG + S V+A FP GAL KKI++ LQ + +++ GN + SPIVT+EPRRRKFH+ IT+T+P+P ++ + P LRLLCSI+G +P WEDITGT+PL+ CVSFTT +SAR WL DC + +E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +E+LE +++ GN+ P + S +QL F+ENRL F +++D+ CG+++F+ +P+ ++ LP IC L+ TLPT + + DE + D + +P + C +++L + VA +G W +L + +EI I ++ + ++++ L W++ K+ + L L + R DIV
Sbjct: 963 VSSPIHSGFLVSFMVDARGGSMRGSRHDGMRIIIPPRKCPAPTRITCRLAKRHRLAYPPPMVEGEGLVSRLVEVGPAGAHFLGPVIVEIPHFGSMRGKERELIVLRSDNGDTWKEH---HYDCRGEDLLALLNGMDEELDSPIELEKKRICRIVTKDFPQYFAVVSRIKQESDHMGPEGGVLTSEAVPMVRAAFPPGALTKKIRVGLQAQPVPEEVVRNVIGNRASFSPIVTVEPRRRKFHKPITMTIPVPPRAKEAAANGRKGDP----APCLRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTNVSARFWLADCQQVSETVALATPLYRELICVPYLAKFVVFAKPTDPMEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEILEGKPIYVDCYGNLAPFSKSSQQLIFTFYAFKENRLPFNVKVRDVGQEACGRLSFLREPKS---------------SKGLPHSAICNLNFTLPTHRKEMESDPDDENDNKDRRHTFASFALRKRYSYLTDPSSSPQSPCE---RTDLRMAIVADHLGLSWTELAREMNFSVDEINHIRTENPNSLTAQSFMLLKKWVSRDG---KNATTDALTAGLTKVNRMDIV 1550 HSP 3 Score: 260.766 bits (665), Expect = 1.317e-69 Identity = 182/557 (32.68%), Postives = 282/557 (50.63%), Query Frame = 2
Query: 1010 KSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTT--------------------MKCEN---------ALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVAR--------------------------------QLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
KS + + L+ A G+ E + G+D++ + L ALH+A+ G++ LLK +V+A G T LHIA Q+ +V L+ A++N+ ++ G TPL++AA E+V LL++GAS S T + EN ALH+AAR + ++ LLL + N + ++ TPLHIA GN ++ LLN GA + + +++ T LH+AAK G + +LLL+ K DAKTK G TPLH ++ G QV QLLL V + + + LT LHVA + HY++ ++++D +AN N NG+TPLH+ KKN ++V +LL+ GA++ A ++ G TP+H+ + G++ I++ L A N G TALH+AA + D+V LL+ A + K + TALH A G+ + V++LLQK +A T G T LHLA ++GH LLL++ ++ K+G T L VA K + A+ L + P+
Sbjct: 40 KSDSNASYLRAARAGN-LEKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKS-AALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPD 594
BLAST of Ankyrin-2 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 789.645 bits (2038), Expect = 0.000e+0 Identity = 408/809 (50.43%), Postives = 567/809 (70.09%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSA--------SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKM 2551
++LRAAR+GN+EK ++L+ + ++ N NGLNA+HLA+KEG+ EVV L++ G SVD AT+KGNT+LHIASLAG+ +VV L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LLE+GA+Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVAAK G M+KLL+ + A +++ T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A + + TE+GLTP+H+AAFMG + IV L +GAS + T ++ E ALH+AAR Q + + LL + A + +A+++QT LHIA R+G IV+ LL GA + T YT LH+A +EG E + LLLEH A TKKGFTPLH+A+KYG+++ A+ LLL + P++ G GLTPLHVA +Y++ + LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA NA +++G +PLHL + G+ +++ LLL NA+VN +NGLT LHLAA+++R + E LL A++ T+ GYT LH A H+G ++ V LL+ +N++T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL +T + +K L+ PE M
Sbjct: 10 SYLRAARAGNLEKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQN-GAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAK-LLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTLRGLTDENLTATPPVSEKHKLNVPETM 815 HSP 2 Score: 403.675 bits (1036), Expect = 1.165e-114 Identity = 212/612 (34.64%), Postives = 335/612 (54.74%), Query Frame = 1
Query: 2851 IQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALG---NLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLP-NWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSND---------------LIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
+ P+ +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E L R++ + + GP+++EIPH ++R ERE++VL+SDNG +WKEH D +D L + E + + + RI RI+T PQYF+++SR+KQ+ +G EGG + S V+A FP GAL KKI++ LQ + +++ GN + SPIVT+EPRRRKFH+ IT+T+P+P +A + LRLLCSI+G +P WEDITGT+PL+ CVSFTT +SAR WL DC + +E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +E+LE +++ GN+ P + S +QL F+ENRL F +++D+ CG+++F+ +P+ ++ LP IC L+ TLPT + + DE + D + +P + C +++L + VA +G W +L + +EI I ++ + ++++ L W++ K+ + L L + R DIV
Sbjct: 946 VSSPIHSGFLVSFMVDARGGSMRGSRHDGMRIIIPPRKCPAPTRITCRLAKRHRLAYPPPMVEGEGLVSRLVEVGPAGAHFLGPVIVEIPHFGSMRGKERELIVLRSDNGDTWKEH---HYDCRGEDLLALLNGMDEELDSPIELEKKRICRIVTKDFPQYFAVVSRIKQESDHMGPEGGVLTSEAVPMVRAAFPPGALTKKIRVGLQAQPVPEEVVRNVIGNRASFSPIVTVEPRRRKFHKPITMTIPVPPRAKEAAANGRKGDPAPCLRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTNVSARFWLADCQQVSETVALATPLYRELICVPYLAKFVVFAKPTDPMEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEILEGKPIYVDCYGNLAPFSKSSQQLIFTFYAFKENRLPFNVKVRDVGQEACGRLSFLREPKS---------------SKGLPHSAICNLNFTLPTHRKEMESDPDDENDNKDRRHTFASFALRKRYSYLTDPSSSPQSPCE---RTDLRMAIVADHLGLSWTELAREMNFSVDEINHIRTENPNSLTAQSFMLLKKWVSRDG---KNATTDALTAGLTKVNRMDIV 1533
BLAST of Ankyrin-2 vs. Ensembl Cavefish
Match: ENSAMXT00000017800.2 (pep primary_assembly:Astyanax_mexicanus-2.0:16:21012912:21225385:-1 gene:ENSAMXG00000017269.2 transcript:ENSAMXT00000017800.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 784.252 bits (2024), Expect = 0.000e+0 Identity = 422/806 (52.36%), Postives = 566/806 (70.22%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNN-ITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARAL--NGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ + SN NGLNA+HLAAKEG+ ++VQ L+E G SVD AT+KGNT+LHIASLAG+ EVV +L++ A+IN +SQNGFTPLYMA+QENHLDVV+ LLE G NQ+ T+DGFTPLA+ALQQG+++VV ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+ N ITPLHVA+K G M++LL+ + + +++ TRDGL+P+HCAARSG + + +LLE GA I ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARAL NGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS + ++ E ALH+AAR Q E + LL + A +ARARE+QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ +++ +LLE TKKGFTPLH+ASKYG + VA+ LLL + P+S G +GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +E+ L+ A N +++G TPLHL S G+ ++ LLL A VN ++GLTALHLAA+++R + E L+K A + +T++GYT L A H+G + V LL+ N VNA+T G T LH AAQQG+ I+ +LL N G TAL +A++ Y+++ +TL V + + +K L+ PE M +
Sbjct: 35 SFLRAARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHMDLVQELLERGSSVDSATKKGNTALHIASLAGQAEVVKILVKQGADINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARQNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPILARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALLQNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQVEVVRCLLRN-GAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLDVASVLLEAGASHSLATKKGFTPLHVASKYGSLDVAK-LLLQRRAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYEAETNILTKQGVTPLHLASQEGHSDMAALLLQKGAQVNVPTKSGLTALHLAAQEDRVGVAEILVKNGASMDQQTKLGYTPLIVACHYGNAKMVNFLLKSNASVNAKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAITVNGNTALAIARRLGYISVVDTLRVVAEEIITTTTTVTEKHKLNVPETMTE 837 HSP 2 Score: 406.371 bits (1043), Expect = 7.814e-115 Identity = 215/519 (41.43%), Postives = 305/519 (58.77%), Query Frame = 1
Query: 2821 WEME-LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRII------------HLNASTQSLDG-------------------PILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT 4281
W E LD++ L PV + FL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ T+P + + E LA R+I HL + L+ P+++EIPH AALR ERE+V+L+S+ G SWKEH +T+ + L + E + E R RI RIIT PQYF+++SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ ++ ++++K GN SPIVTLEPRRRKFH+ IT+T+P+P S + T +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SA WLIDC + E V A+ +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE + + GN++P+T S + F+ENRL+ + +I+D + PCG+++FM++PR + L IC L+ITLPT
Sbjct: 906 WGTENLDNIALSSSPVHS-FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCGAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLPVIVEIPHFAALRGKERELVILRSETGESWKEHHCEYTEEELNQILNGMDE-LDPPEELERKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGILSSTVVPQVQAVFPEGALTKRIRVGLQAQSVNMDVVRKILGNKATFSPIVTLEPRRRKFHKPITMTIPIPKSSTDPVLNGFGGDTPTLRLLCSITG-TTPAQWEDITGTTPLTFINDCVSFTTNVSA-FWLIDCRQAQESVNFATQVYREIICVPYMAKFVVFAKTHDPIEARLRCFCMTDDKIDKTLEQQENFTEVARSRDVEVLEGKPIYADCFGNLVPLTKSGQHHLFSFFAFKENRLALFIKIRDNTQEPCGRLSFMKEPRS---------------YRSLAHNAICNLNITLPT 1405 HSP 3 Score: 250.751 bits (639), Expect = 3.243e-66 Identity = 179/561 (31.91%), Postives = 287/561 (51.16%), Query Frame = 2
Query: 1010 KSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTT--------------------MKCEN---------ALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDN-YTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSA----------KVNPNSLGHHG-----------------------LTPLHVATYYNHYEMIELLLDTEANVN--CLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
KS + + L+ A G+ +V + L G+D+ + L ALH+AA G+++ + LL+ +V++ G T LHIA Q+++V++L+K A IN+ ++ G TPL++A+ ++V LL+NG + S T + EN ALH+AAR + ++ LLL + N + +++ TPLHIA GN ++ LLN GA + + N T LH+A+K G + RLLL+ + DAKT+ G TPLH A++ G A +LLL ++P + G LT LHVA + HY + +LLLD AN N L +NG+TPLH+ KKN ++V +LL+ GA++ A ++ G TP+H+ + G+ I+ LLL A + G TALH+AA + ++V LL+ A + + + T LH A G+ + V++LLQ +A T G T LH++A++G + + +LL+ + K+G T L VA K L++A+ L + P+
Sbjct: 29 KSDSNTSFLRAARAGNIDKVLEYL-KGGVDIGTSNQNGLNALHLAAKEGHMDLVQELLERGSSVDSATKKGNTALHIASLAGQAEVVKILVKQGADINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKS-AALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARQNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGH-DTAVELLLERGAPILARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALLQNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQVEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLDVASVLLEAGASHSLATKKGFTPLHVASKYGSLDVAKLLLQRRAPPD 586
BLAST of Ankyrin-2 vs. Ensembl Cavefish
Match: ank3b (ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2]) HSP 1 Score: 770 bits (1987), Expect = 0.000e+0 Identity = 390/765 (50.98%), Postives = 553/765 (72.29%), Query Frame = 2
Query: 179 VEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
+EK ++L++ + ++ N NGLNA+HLA+KEG+ EVV LI+ G +VD AT+KGNT+LHIASLAG+ +VV L+ + AN+N +SQNGFTPLYMAAQENHLDVV+ LL+ G++Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVA+K G M+KLL+ + A +++ T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L++ + VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A I + TE+GLTP+H+AAFMG + IV L+ +GAS + T ++ E ALH+AAR Q E K L+ + A +A+++++QTPLHI+ R+G I++QLL GA P+ T YT LH+AA+EG +++ +LL+ TKKGFTPLH+A+KYG+++VA LLL + P++ G GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA+ NA +++G +PLHL S GN +++ LL+ +A +N ++GLT LHLAA++++ ++ E L+ A + +T+MGYT LH A H+G ++ V LL+ VNA+T + AAQQGH I+ LLL + N G TAL +A++ Y+++ +TL
Sbjct: 1 LEKALDYLKSGVDINICNQNGLNALHLASKEGHVEVVTQLIKMGATVDAATKKGNTALHIASLAGQSDVVKELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRYLLDNGSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVKLLLERGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHEVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVTQLMNHGASPNTTNVRGETALHMAARAGQTEVVKYLVQN-GAYVDAKSKDDQTPLHISSRLGKPEIIQQLLQHGACPDSTTTSGYTPLHLAAREGHKDVASILLDQGASLGITTKKGFTPLHVAAKYGKIEVA-NLLLQKRAPPDASGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMEIATTLLEYGADTNAITRQGISPLHLASQEGNVDMVTLLMARDATINLCNKSGLTPLHLAAQEDQVNVAEVLVNHGATVDPETKMGYTPLHVACHYGNVKMVHFLLKNQAKVNAKTKV------TAAQQGHTHIINLLLQHGAAPNELTVNGNTALSIARRLGYISVVDTL 756 HSP 2 Score: 423.32 bits (1087), Expect = 1.571e-121 Identity = 228/606 (37.62%), Postives = 349/606 (57.59%), Query Frame = 1
Query: 2833 LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTV-QTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQK-----GLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
LD+V L+ P+ +GFL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ + P + + E LA R++ + + GP+++EIPH ++R ERE+++L+S+NG +WKEH A+ + L + E +++ E + RI RIIT PQYF+++SR+KQ+ +G EGG ++S VQA FPEGAL KKI++ LQ + ++K GN SPIVT+EPRRRKFH+ IT+T+P+P S + Y T LRLLCSI+G +P WEDITGT+PLT + CVSFTT +SAR WL DC++ + V +A+ LY E VP++ +F+VF + + E +RC C+TDD +KTLE QENFE ++ +EVLE +++ GN+ P+T + +QL L F+ENRL F +I+D S PCG+++F+ EL + G +PQ +C L+ITLP K T+K ++ + P + C +++L + VA +G W +L + +EI I +++ + ++++ L W+ K+ + L +L I R DIV
Sbjct: 890 LDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHNGMRIIIPPRKCTAPTRITCRLVKRHKLASPPPMVEGEGLASRLVEVGPAGAHFLGPVIVEIPHFGSMRGKERELIILRSENGETWKEHQYDCRTEALNELLNGMDEELESLEELEKKRICRIITKDFPQYFAVVSRIKQESNQMGPEGGVLSSMTVPHVQASFPEGALTKKIRVGLQAQPVPDETVKKILGNRATFSPIVTVEPRRRKFHKPITMTIPVPPLSGEGVTNGYKGDSTPCLRLLCSITGGTSPAQWEDITGTTPLTFVNDCVSFTTNVSARFWLADCHQIPDTVGLATQLYRELICVPYMAKFVVFAKMNDPVESNLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLTPLTKAGQQLLLNFYAFKENRLPFCVKIRDNSQEPCGRLSFLR---------ELKTSKG------IPQTAVCNLNITLPALKKTEKPERRHTFASLALRKRYSYLTEPGMSPQSPCE---RTDLRMAIVADHLGLSWTELAREMDFSVDEINHIRVENPNSLTTQSFMLLKKWVNRDG---KNATTDVLTAALTKINRMDIV 1474 HSP 3 Score: 319.701 bits (818), Expect = 5.923e-88 Identity = 216/640 (33.75%), Postives = 329/640 (51.41%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLL-LSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELL 2077
AAR + + LQ D D+ + +G +H+AA GN V LL+ G +VD R T LH+AS G +V LLLE A I+ K+++G TPL+ A+ H VV++LL+ GA T +G +PL +A Q + VQ+L LH DDV L T LH+AAH + VAK++++K A+ N A N TPLH+A K + ++++LL+ A++ +VT GL+PIH AA G ENI+ L+ +GA + G TAL MA + Q EV K L+ G VDA + D T LH+++ G + LL++ ++ +G+TPLH+A ++ + +L+ A + TT+ G TPLH+AA G E+ N+LL+ A + LH+AA + ++ +LLL A+ +A A+ TPLHIA + I LL GAD N +T+ + LH+A++EG ++ LL+ + K G TPLH+A++ +V VA L+ A V+P + G TPLHVA +Y + +M+ LL +A VN K A++ + LL+ GA N + G T L + G +++ L
Sbjct: 156 AARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVKLLLERGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL-------------LHHEVPVDDVTNDYL-----------------TALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVTQLMNHGASPNTTNVRGETALHMAARAGQTEVVKYLVQNGAYVDAKSKDDQTPLHISSRLGKPEIIQQLLQHGACPDSTTTSGYTPLHLAAREGHKDVASILLDQGASLGITTKKGFTPLHVAAKYGKIEVANLLLQKRAPPDASGKSGLTPLHVAAHYDNQKV-ALLLLDQGASPHAAAKNGYTPLHIAAKKNQMEIATTLLEYGADTNAITRQGISPLHLASQEGNVDMVTLLMARDATINLCNKSGLTPLHLAAQEDQVNVAEVLVNHGATVDPET--KMGYTPLHVACHYGNVKMVHFLLKNQAKVNAKTKV------TAAQQGHTHIINLLLQHGAAPNELTVNGNTALSIARRLGYISVVDTL 756
BLAST of Ankyrin-2 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 768.844 bits (1984), Expect = 0.000e+0 Identity = 401/798 (50.25%), Postives = 555/798 (69.55%), Query Frame = 2
Query: 182 EKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSA--------SGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKM 2551
EK ++L+ + ++ N NGLNA+HLA+KEG+ EVV L++ G SVD AT+KGNT+LHIASLAG+ +VV L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LLE+GA+Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVAAK G M+KLL+ + A +++ T+DGL+P+HC ARSG E ++ +LL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A+V++ N NA+ALNGFTPLHIACKK + K++ELL+K+ A + + TE+GLTP+H+AAFMG + IV L +GAS + T ++ E ALH+AAR Q + + LL A + +A+++QT LHIA R+G IV+ LL GA + T YT LH+A +EG E + LLLEH A TKKGFTPLH+A+KYG+++ A+ LLL + P++ G GLTPLHVA +Y++ + LLLD A+ + KNGYTPLH+ AKKN +E+ L++ GA NA +++G +PLHL + G+ +++ LLL NA+VN +NGLT LHLAA+++R + E LL A++ T+ GYT LH A H+G ++ V LL+ +N++T G T LH AAQQGH I+ +LL + N G TAL +A++ Y+++ +TL +T + +K L+ PE M
Sbjct: 1 EKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVR-YLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAK-LLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTLRGLTDENLTATPPVSEKHKLNVPETM 795 HSP 2 Score: 390.963 bits (1003), Expect = 7.990e-110 Identity = 187/477 (39.20%), Postives = 282/477 (59.12%), Query Frame = 1
Query: 2875 FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALG---NLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLP-----NWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT 4281
FL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ P + + E L R++ + + GP+++EIPH ++R ERE++VL+SDNG +WKEH D +D L + E + + + RI RI+T PQYF+++SR+KQ+ +G EGG + S V+A FP GAL KKI++ LQ + +++ GN + SPIVT+EPRRRKFH+ IT+T+P+P ++ + P LRLLCSI+G +P WEDITGT+PL+ CVSFTT +SAR WL DC + +E V +A+ LY E VP++ +F+VF + + E ++RC C+TDD +KTLE QENFE ++ +E+LE +++ GN+ P + S +QL F+ENRL F +++D+ CG+++F+ +P+ ++ LP IC L+ TLPT
Sbjct: 929 FLVSFMVDARGGSMRGSRHDGMRIIIPPRKCPAPTRITCRLAKRHRLAYPPPMVEGEGLVSRLVEVGPAGAHFLGPVIVEIPHFGSMRGKERELIVLRSDNGDTWKEH---HYDCRGEDLLALLNGMDEELDSPIELEKKRICRIVTKDFPQYFAVVSRIKQESDHMGPEGGVLTSEAVPMVRAAFPPGALTKKIRVGLQAQPVPEEVVRNVIGNRASFSPIVTVEPRRRKFHKPITMTIPVPPRAKEAAANGRKGDPAPC----LRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTNVSARFWLADCQQVSETVALATPLYRELICVPYLAKFVVFAKPTDPMEARLRCFCMTDDKVDKTLEQQENFEEVARSKDIEILEGKPIYVDCYGNLAPFSKSSQQLIFTFYAFKENRLPFNVKVRDVGQEACGRLSFLREPKS---------------SKGLPHSAICNLNFTLPT 1383 HSP 3 Score: 340.502 bits (872), Expect = 6.597e-94 Identity = 226/659 (34.29%), Postives = 345/659 (52.35%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHL 2137
AA GN+ L D N + +H+AAK GN +V+LL++ G +D T+ G T LH + +G +VV +LL+ A I K++NG +PL+MA Q +HL+ V++LL++ T+D T L VA G+ KV ++++D KK + NA +L +GFTPLHIA N V V +LL++ A + ++ +TP+HVAA G E ++K L A+ N+ G + +H AAR+G +++ LL+NGA + K+K+ TAL +A++ +AE+ + L+ KG A T T LH+A G+ A +LL++ +++A GFTPLH+A K Q + +LL++ +A ++ +TGLTPLH+AA ++ + +LL +GAS LH+AA+ NQ E LL A NA R+ +PLH+A + G+ +V LL A+ NM K+ T LH+AA+E R ++ +LL H + DA TK G+TPLH+A YG +++ LL + NS G TPLH A H +I +LL A+ N L NG T L + + I V L RG + ++ P+ E M LD + D A G T +L
Sbjct: 196 AAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVD----------------KKANPNAKAL--------------NGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLE-IGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMV-SFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTL--RG--LTDENLTATPPVSEKHKLNVPETMNEFLDMSDDEGEDAMTGETEKYL 818 HSP 4 Score: 274.248 bits (700), Expect = 1.857e-73 Identity = 182/525 (34.67%), Postives = 291/525 (55.43%), Query Frame = 2
Query: 116 ETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNA-NGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSR---SKVR-LPALHIAAK--KDDV------NAASLLIGSSDDNV------------------------DHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQL 1579
+TKD LT H ARSG+ E+V E L P +S NGL+ +H+A + + VQLL+++ + VD T T+LH+A+ G +V ++++ KAN N K+ NGFTPL++A ++N + V+++LL++GA+ T+ G TP+ VA G++ +V+ L + + + VR ALH+AA+ + DV N A + I + DD + SG+TPLH+A + A LL+E A ++ K TPLHVAAK+G+ E KLL+ ++A ++ + GL+P+H AA + + L+LL++GA +KNG T L +A + +Q E+ TL+ G + +AVT ++ LH+AA G+++ +LL N NVN NG TPLH+A ++ + + E+L+ + A +++ T+TG TPLH+A G+ ++V+ LL+N A I+ T LH AA+ +LL H A+ N T L IA R+G S+V+ L
Sbjct: 251 KTKDGLT-PLHC---GARSGH-EQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQH-RASANELTLNGNTALSIARRLGYISVVDTL 769
BLAST of Ankyrin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 799.66 bits (2064), Expect = 0.000e+0 Identity = 417/809 (51.55%), Postives = 572/809 (70.70%), Query Frame = 2
Query: 134 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLS-AKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
++ A +FLRAAR+GN+E++ + L+ + + N NGLNA+HLA+KEG+ +VV L++ +D AT+ GNT+LHIA+LAG+ ++V +L+E ANIN +SQNGFTPLYMAAQENHL++VK LL+ GANQ++ T+DGFTPLAVALQQG+++VV +LL++D++ KVRLPALHIAA+KDD NAA+LL+ + N D S SGFTPLHIAAHY N+NVA LL+ A V+F A+N ITPLHVAAK G M+KLL+ + A +++ TRDGL+P+HCAARSG E +I +LLE A I K+KNGL+ L MATQG+ + L+ + VD VT+DYLT LHVAAHCG+ A++LL NARALNGFTPLHIACKK + K++ELL+K+ A I++TTE+GLTP+H+A+FMG +V +LL+NGAS + T ++ E LH+A+R Q E K LL A +ARE+QTPLHIA R+G IV+ LL G+DPN T T L+ A++EG +++ LLLE+ TKKGFTPLHIASKYGR++VA LL A +P G +GLTPLHVAT+Y+H ++ LLLD A+ + KNGYTPLH+ AKKN +EV K+L++ GA N +Q+G PLHL + G+ +++ LLL +A ++ + GLTA+HLAA++++ ++ E L K +AD++T T++ YT LH A H+G I+ V LL+ VNA+T G T LH AAQQGH +V LL +E N G TAL +A++ Y+++ +TLS +T P + +K L+ PE M D
Sbjct: 9 SDAATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLL-QHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKT-LLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGYISVVDTLSILTEEPVTGVNTVIEKHKLNVPETMND 815
BLAST of Ankyrin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 791.571 bits (2043), Expect = 0.000e+0 Identity = 414/815 (50.80%), Postives = 573/815 (70.31%), Query Frame = 2
Query: 134 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIG-------SSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
++ A +FLRAAR+GN+E++ + L+ + + N NGLNA+HLA+KEG+ +VV L++ +D AT+ GNT+LHIA+LAG+ ++V +L+E ANIN +SQNGFTPLYMAAQENHL++VK LL+ GANQ++ T+DGFTPLAVALQQG+++VV +LL++D++ KVRLPALHIAA+KDD NAA+LL+ +S ++ + SGFTPLHIAAHY N+NVA LL+ A V+F A+N ITPLHVAAK G M+KLL+ + A +++ TRDGL+P+HCAARSG E +I +LLE A I K+KNGL+ L MATQG+ + L+ + VD VT+DYLT LHVAAHCG+ A++LL NARALNGFTPLHIACKK + K++ELL+K+ A I++TTE+GLTP+H+A+FMG +V +LL+NGAS + T ++ E LH+A+R Q E K LL A +ARE+QTPLHIA R+G IV+ LL G+DPN T T L+ A++EG +++ LLLE+ TKKGFTPLHIASKYGR++VA LLL + + G +GLTPLHVAT+Y+H ++ LLLD A+ + KNGYTPLH+ AKKN +EV K+L++ GA N +Q+G PLHL + G+ +++ LLL +A ++ + GLTA+HLAA++++ ++ E L K +AD++T T++ YT LH A H+G I+ V LL+ VNA+T G T LH AAQQGH +V LL +E N G TAL +A++ Y+++ +TLS +T P + +K L+ PE M D
Sbjct: 8 SDAATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKT-LLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVA-TLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGYISVVDTLSILTEEPVTGVNTVIEKHKLNVPETMND 820
BLAST of Ankyrin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 504.982 bits (1299), Expect = 1.322e-153 Identity = 261/523 (49.90%), Postives = 358/523 (68.45%), Query Frame = 2
Query: 917 RDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
+DGL+P+HCAARSG E ++ ILLE GA I K+KNGL+ L MATQGD E + L+ VD +T+DYLTALHVAAHCG+ A+VLL N N RALNGFTPLHIACKK + +++ELL+KY A I + TE+GLTP+H++AFMG+ IV ILL+ GAS + T ++ E ALH+AAR Q E + LL + A +A+ARE QTPLHIA R+G IV+ LL A P+ T + YT LH+AA+EG +++ +LLEH TKKGFTPLH+ASKYG+++VA LLL +P++ G +GLTPLHVA++Y++ ++ LLLD A+ + KNGYTPLH+ AKK+ +E+ L++ GA NA +++G PLHL + G+ ++ LLL ADVNH ++GL+ LHLAA++++ ++ E L+K A ++ T++GYT L A H+G I+ V LLQ DVN++T G T LH AAQQGH IV LLL N G TAL +A++ Y+++ +TL VT
Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRN-GAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVA-SLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVT 524 HSP 2 Score: 305.449 bits (781), Expect = 4.832e-85 Identity = 185/517 (35.78%), Postives = 289/517 (55.90%), Query Frame = 2
Query: 725 GFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKML 2275
G TPLH AA + V ++L+E+ A + KN ++PLH+A + E +++L+ +A V+ +T D L+ +H AA G +LL+ GA+ ++ NG T L +A + ++ V + L+ G ++AVT LT +HV+A GN+N +LL+ + NA + G T LH+A + Q+++V L++ A +++ TPLHIAA +G EIV +LL++ AS T LH+AAR E+ ILL H A+ ++ TPLH+A + G + LL A P+ K+ T LH+A+ +++ LLL+ P A K G+TPLHIA+K ++++A LL N++ G+ PLH+ H ++ LLL A+VN K+G +PLHL A+++ + V ++L+ GA+VNA ++ G+TPL + GN +++ LL ADVN + +NG T LH AA++ T IV LLK A + T G TAL A G I V L
Sbjct: 6 GLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEH-GASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIA-TTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520 HSP 3 Score: 296.975 bits (759), Expect = 3.011e-82 Identity = 194/540 (35.93%), Postives = 295/540 (54.63%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNA-NGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQL 1777
AARSG+ E+V E L P ++ NGL+ +H+A + + E VQ+L++ VD T T+LH+A+ G +LL+ AN NV++ NGFTPL++A ++N + V+++LL+YGA+ T+ G TP+ V+ GN +V ILL G+S + + G T LH+AA V + L+ A V+ A+ TPLH+AA+ GK E+++LL+ A+ ++ T +G +P+H AAR G E++ ILLE+GA + +K G T L +A++ + EV L+ + DA + LT LHVA+H N A +LL + +A A NG+TPLHIA KK Q ++ L++Y A N+ T G+ PLH+ A G ++ ++LL A ++ T + LHLAA+ ++ +IL+ H A+ NA + TPL +A GN +V LL GAD N TK+ YT LH AA++G I LLL+ +P+ T G T L IA + G + V L
Sbjct: 13 AARSGH-EQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQG---------------------------GASPNATN---VRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKH-GAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520 HSP 4 Score: 296.975 bits (759), Expect = 3.261e-82 Identity = 188/549 (34.24%), Postives = 298/549 (54.28%), Query Frame = 2
Query: 431 QNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELL 2077
Q+G TPL+ AA+ H VV++LLE GA T +G +PL +A Q + + VQ+L+ + R P DD+ +D+ T LH+AAH + AK+L++K A+ N A N TPLH+A K + +++LL+ A++ +VT GL+P+H +A G NI+LILL+ GA + G TAL MA + Q EV ++L+ G VDA + T LH+AA G + ++LL++ + +A NG+TPLH+A ++ + +L+++ A + TT+ G TPLH+A+ G E+ ++LL+ AS LH+A+ + ++ +LLL A+ +A A+ TPLHIA + I LL GA+ N +T+ LH+ A+EG +++ LLL + TK G +PLH+A++ +V VA ++L+ + N+ G TPL VA +Y + +M+ LL A+VN KNGYTPLH A++ + LL+ GA N + G T L + G +++ L
Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLM------QYRAPV-------DDI------------TLDY-----LTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKV-ALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVA-EILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520 HSP 5 Score: 277.33 bits (708), Expect = 5.492e-76 Identity = 186/560 (33.21%), Postives = 301/560 (53.75%), Query Frame = 2
Query: 533 DGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQL-LKTEADISTKT 2209
DG TPL A + G+++VV+ILL+ + I AK + +G +PLH+A ++V ++L++ A V+ + +T LHVAA G K+L+ + AN N +G +P+H A + ++ +LL+ GA I+ +++GLT + ++ + L+ G +A + TALH+AA G LL+N V+A+A TPLHIA + + ++V+LL+++ A ++ T G TPLH+AA G +++ ILL++GAS++ TT K LH+A++ + E LLL A+ +A + TPLH+A N + LL+ GA P+ K+ YT LHIAAK+ + EI+ LLE+ + +A T++G PLH+ ++ G VA LLL+ + N GL+PLH+A + + E+L+ A+VN K GYTPL + I++ L+ GA+VN++++ G+TPLH + G+ I+ LLL A N NG TAL +A +V+ L + TE I++ T
Sbjct: 5 DGLTPLHCAARSGHEQVVEILLEQGAP---------ILAK---------------------TKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVAS-LLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVA-SLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVTEETITSTT 532 HSP 6 Score: 187.578 bits (475), Expect = 5.719e-48 Identity = 107/295 (36.27%), Postives = 166/295 (56.27%), Query Frame = 2
Query: 1613 KDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
+D T LH AA+ G ++ +LLE AKTK G +PLH+A++ V+ Q+L+ + + + LT LHVA + HY ++LLD AN N NG+TPLH+ KKN I V +LL+ GA++ A ++ G TP+H+++ GN I+ +LL A N G TALH+AA +T++V LL+ A + K + T LH A G+++ V++LLQ +A T+ G T LH+AA++GH + +LL++ + K+G T L VA K + +A L + P+
Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECV-QVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPD 297 HSP 7 Score: 187.193 bits (474), Expect = 6.783e-48 Identity = 102/298 (34.23%), Postives = 165/298 (55.37%), Query Frame = 1
Query: 3655 LCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERM-CRTIVKSELN-----IREVALKV------GGDWKKLTINLGMGQEEITRIDLQSGTEED 4512
L +++G P WEDITGT+PLT CVSFTT +SAR WLIDC +T+E V + +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE ++E GN++P+T + +Q +L F+ENRL F +I+D + CG++ FM+D + + LPQ +C L+I LP P +K ++ +P+ ++E + C +I+K+ L I +++L+V D L + + +E++ ++ GT+ D
Sbjct: 959 LMTLTGGTAPAQWEDITGTTPLTFTKQCVSFTTNVSARFWLIDCRQTHEAVNFTTQMYRELVCVPYMAKFVVFAKTHDPVEARLRCFCMTDDKVDKTLEQQENFSEMARSRDVEVLEGKPIYVECFGNLVPLTKAGQQHALSFYAFRENRLPFMVKIRDSNQEACGRLCFMKDAKT---------------ARGLPQAAVCNLNIMLP--PYKKETDS-----------DPEPEEEAVSCTSIIKNILKSPQCQIVKISLRVKLPLLSSEDRHALLLEVAEMKEDLLKVTALLGTDSD 1228 HSP 8 Score: 108.997 bits (271), Expect = 5.942e-24 Identity = 58/155 (37.42%), Postives = 82/155 (52.90%), Query Frame = 1
Query: 2833 LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKE----LYPTL-----------------------------PLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEH 3198
LD+V L P+ +GFL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ L P L P L D E+L RI+ L + GP+++EIPH A+LR ERE+VVL+S+NG +W+EH
Sbjct: 668 LDNVALSSSPIHSGFLVSFMVDARGGSMRGCRHHGLRIVIPPRKCMAPTRVTCRLVKRHRLAALPPVLEGEGLASRVVEVGPSGGQFLGKLHLPNTPPPLNDGESLVSRILQLGPPGTTFLGPVIVEIPHFASLRGKERELVVLRSENGETWREH 822 HSP 9 Score: 92.0485 bits (227), Expect = 1.000e-18 Identity = 51/153 (33.33%), Postives = 85/153 (55.56%), Query Frame = 2
Query: 2003 AQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNI 2461
A Q G TPLH + +G+++++E+LL+ A + + +NGL+ LH+A + + + V+ L++ A + T TALH A H G +T K+LL K + N + G T LH+A ++ I ++ LLL + + GLT + V+ LNI
Sbjct: 1 AHRQDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNI 153
BLAST of Ankyrin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 399.438 bits (1025), Expect = 1.787e-118 Identity = 210/436 (48.17%), Postives = 294/436 (67.43%), Query Frame = 2
Query: 1178 LLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
LL N N RALNGFTPLHIACKK + +++ELL+KY A I + TE+GLTP+H++AFMG+ IV ILL+ GAS + T ++ E ALH+AAR Q E + LL + A +A+ARE QTPLHIA R+G IV+ LL A P+ T + YT LH+AA+EG +++ +LLEH TKKGFTPLH+ASKYG+++VA LLL +P++ G +GLTPLHVA++Y++ ++ LLLD A+ + KNGYTPLH+ AKK+ +E+ L++ GA NA +++G PLHL + G+ ++ LLL ADVNH ++GL+ LHLAA++++ ++ E L+K A ++ T++GYT L A H+G I+ V LLQ DVN++T G T LH AAQQGH IV LLL N G TAL +A++ Y+++ +TL VT
Sbjct: 1 LLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRN-GAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVA-SLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVT 434 HSP 2 Score: 265.774 bits (678), Expect = 2.502e-73 Identity = 162/439 (36.90%), Postives = 243/439 (55.35%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKIL 1477
+A GN+ V LQ P+ +N G A+H+AA+ G EVV+ L+ NG VD R+ T LHIA+ GKLE+V LLL+ A+ + + NG+TPL++AA+E H DV +LLE+GA+ A+TT GFTPL VA + G +V +LL R + A K +G TPLH+A+HY+N VA LL+++ A + AKN TPLH+AAK + E+ L+ A N++TR G++P+H A+ G ++ +LL AD+ H +K+GL+ L +A Q D+ V + L+ G V+A T T L VA H GNI LL++ +VN++ NG+TPLH A ++ + +V LL+K A N T G T L IA +G +V+ L +++ T+ + ++RN E ++L
Sbjct: 55 SAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQ-------RFASPDAAGK-----------------------NGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL----KVVTEETITSTTVSNPSSRNVPETMTEVL 459 HSP 3 Score: 242.276 bits (617), Expect = 1.198e-65 Identity = 150/457 (32.82%), Postives = 253/457 (55.36%), Query Frame = 2
Query: 296 LIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDN----DSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEG 1654
L++ G + ++ G T LHIA ++ V+ LLL+ A+I +++G TP++++A +L++V +LL+ GA+ T G T L +A + G +VV+ LL N D++++ LHIAA+ + LL+ + D +++G+TPLH+AA + +V +L+E A + K TPLHVA+K+GK E+ LL+ + A+ ++ ++GL+P+H A+ + + L+LL+ GA +KNG T L +A + DQ E+ TL+ G + +A+T + LH+ A G+ + A +LL +VN +G +PLH+A ++ + + E+L+K+ AH+N+TT+ G TPL +A G+ ++VN LL++GA + N++ + TPLH A + G+ IV LL GA PN VT + TAL IA + G
Sbjct: 1 LLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLL-QHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADV----------------------------------NSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLG 422 HSP 4 Score: 184.496 bits (467), Expect = 2.145e-47 Identity = 85/208 (40.87%), Postives = 125/208 (60.10%), Query Frame = 1
Query: 3655 LCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP 4278
L +++G P WEDITGT+PLT CVSFTT +SAR WLIDC +T+E V + +Y E VP++ +F+VF + + E ++RC C+TDD +KTLE QENF ++ VEVLE ++E GN++P+T + +Q +L F+ENRL F +I+D + CG++ FM+D + + LPQ +C L+I LP
Sbjct: 835 LMTLTGGTAPAQWEDITGTTPLTFTKQCVSFTTNVSARFWLIDCRQTHEAVNFTTQMYRELVCVPYMAKFVVFAKTHDPVEARLRCFCMTDDKVDKTLEQQENFSEMARSRDVEVLEGKPIYVECFGNLVPLTKAGQQHALSFYAFRENRLPFMVKIRDSNQEACGRLCFMKDAKT---------------ARGLPQAAVCNLNIMLP 1027 HSP 5 Score: 123.25 bits (308), Expect = 2.507e-28 Identity = 54/122 (44.26%), Postives = 80/122 (65.57%), Query Frame = 1
Query: 2833 LDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEH 3198
LD+V L P+ +GFL+SF+VDA+GG M+ RH +RI +P PTR+ C L ++ LP + + E LA R++ + S GP+++EIPH A+LR ERE+VVL+S+NG +W+EH
Sbjct: 577 LDNVALSSSPIHSGFLVSFMVDARGGSMRGCRHHGLRIVIPPRKCMAPTRVTCRLVKRHRLAALPPVLEGEGLASRVVEVGPSGGQFLGPVIVEIPHFASLRGKERELVVLRSENGETWREH 698
BLAST of Ankyrin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006531.1 (pep scaffold:Pmarinus_7.0:GL477280:1359:33855:1 gene:ENSPMAG00000005898.1 transcript:ENSPMAT00000006531.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 359.762 bits (922), Expect = 1.113e-100 Identity = 186/436 (42.66%), Postives = 273/436 (62.61%), Query Frame = 1
Query: 3010 LYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDA-------------NRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLP 4278
L T P L + E+L R++ L S GP+L+EIPH A+LR ERE+VVL+S +G +WKEH N + + D L + E + + E R RI RI+T PQYF+++SR++Q+ +G EGG ++ +V V+A FP+GAL K+IK+ LQ H + ++++K GN A SPIVT+EPRRRKFH+ IT+T+P+P + A + ++P T LRLLCSI+G +P WEDITGT+PLTI VSFTT +SAR WL+ C + E V +A+ LY+E+ VP++ F+VF + E ++RC C+TDD +KTLE QENF ++ VEV+E ++E GN++P+T S +Q S F+ENRL FY +++D++ PCG++ FM+DP+ T+ LPQ+ IC+L+IT+P
Sbjct: 4 LPSTPPPLNEGESLVSRLLQLGPEGTSFIGPVLVEIPHFASLRGRERELVVLRSGDGKTWKEHQNDCKNDDLNDVLNGMDEELDSLEELERKRICRIVTRDFPQYFAVVSRVRQESEVVGPEGGVLSCTVVPDVRASFPQGALTKRIKVGLQAHPVPEDMVRKVLGNKAAFSPIVTVEPRRRKFHKPITMTIPVPQSTSAITAASADTRVNGFSETVPDT--PPPLRLLCSITGGISPAHWEDITGTTPLTITTSTVSFTTNVSARFWLLYCRQPPEAVNLANRLYQEATCVPYLATFVVFSKAVEAVESRLRCFCMTDDRVDKTLEQQENFTEVARSRDVEVMEGKPIYVECFGNLVPLTKSGQQHSFNFYAFKENRLPFYVKVRDVTQEPCGRLCFMKDPKT---------------TRGLPQQAICSLNITIP 422
BLAST of Ankyrin-2 vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]) HSP 1 Score: 80.1073 bits (196), Expect = 5.028e-17 Identity = 55/155 (35.48%), Postives = 81/155 (52.26%), Query Frame = 2
Query: 152 FLRAARSGNVEKVKEFLQADIKPDMSNA--NGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLE-SKANINVKSQNGFTPLYMAAQENHLDVVKVLLE-YGANQAITTDDGFTPLAVALQQGNDKVVQILLDN 604
F A GN+E VK +KPD++ G+ +HLA + EV Q LIENG SV I + LH A+ G L+++ LL K+ +N + + G+TPL+ A E H D +L+E YGA + + G VAL N++V + L+N
Sbjct: 76 FHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVAL---NEQVKKFFLNN 227 HSP 2 Score: 74.3294 bits (181), Expect = 5.022e-15 Identity = 67/224 (29.91%), Postives = 104/224 (46.43%), Query Frame = 2
Query: 1829 PLHVATYYNHYEMIELLLDTEANVNCLYKN--GYTPLHLVAKKNMIEVTKLLIDRGANVNAQS---QKGFTPLHLNSMAGNKEIMELLLDA--NADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKML--LQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDN---EIDV--NHQNKQGLTALEVAQKQHYLN 2458
PLH A N + ++ LL ++ ++ L K+ G PLH E+T L+ + NVN G+TP H+ GN E+++ L D D+N G+T LHLA K ++ + L++ A + K + LH A G ++ +++L L K+ VN Q G T L A +GH LL++ E D+ N K AL K+ +LN
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSL-LLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKS-AVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALNEQVKKFFLN 226 HSP 3 Score: 70.8626 bits (172), Expect = 7.915e-14 Identity = 53/176 (30.11%), Postives = 88/176 (50.00%), Query Frame = 2
Query: 1529 PLHIAVRMGNYSIVEQLLNAGADPNMV---TKDNYTALHIAAKEGRHEISRLLL---EHQCKPDAKTKKGFTPLHIASKYGRVQVARQLL-LSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGAN-VNAQSQKGFTPL 2032
PLH A + V++LL++ P+++ +D LH + HEI+ LL E+ D G+TP HIA G ++V + L K + N + + G+T LH+A +E+ + L++ A+V K PLH A +++ +LL G + VN Q ++G+TPL
Sbjct: 5 PLHQACMENEFFKVQELLHS--KPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPL 178 HSP 4 Score: 63.1586 bits (152), Expect = 3.306e-11 Identity = 49/182 (26.92%), Postives = 87/182 (47.80%), Query Frame = 2
Query: 86 EFFRIFQMVEETKDSLTEK---AHAFLRAARSGNVEKVKEFLQADIK----PDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDI--ATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTD-DGFTPLAVALQQGNDKVVQILLD 601
EFF++ +++ L +K L + S ++ FL + ++ D + +G H+A GN EVV+ L + L D+ T +G T LH+A EV L+E+ A++ +K + PL+ AA L ++++L G + D G+TPL AL +G+ +L++
Sbjct: 14 EFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVE 195 HSP 5 Score: 62.3882 bits (150), Expect = 7.123e-11 Identity = 47/158 (29.75%), Postives = 76/158 (48.10%), Query Frame = 2
Query: 1706 KTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGH---HGLTPLHVATYYNHYEMIELLLDT--EANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLD-ANADVNHQAENGLTALHLAAEKNRTD 2161
K + G PLH + + ++ LLS N N + G TP H+A + E+++ L D + ++N + G T LHL K EV++ LI+ GA+V + + PLH + G+ +++ELL + VN Q + G T L A + D
Sbjct: 32 KDQDGRIPLHWSVSFQAHEIT-SFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGD 188 HSP 6 Score: 60.4622 bits (145), Expect = 2.563e-10 Identity = 61/221 (27.60%), Postives = 92/221 (41.63%), Query Frame = 2
Query: 341 NTSLHIASLAGKLEVVSLLLESKANINV-KSQNGFTPLYMAAQENHLDVVKVLLEYGAN---QAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLIS-QKANVNSVTRDGLSPIHCAARSGFENIILILLE 988
N LH A + + V LL SK ++ + K Q+G PL+ + ++ LL N D G+TP +A GN +VV+ L D K D+N + G T LH+A V++ LIE A V K N PLH AA G ++++LL K+ VN + G +P+ A G + ++L+E
Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDR--------------PLKPDLNKIT--------------NQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVE 195 HSP 7 Score: 59.3066 bits (142), Expect = 6.397e-10 Identity = 60/222 (27.03%), Postives = 92/222 (41.44%), Query Frame = 2
Query: 1229 PLHIACKKIQS-KMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADP--NMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLD 1885
PLH AC + + K+ ELL + + + G PLH + + EI + LL K EN N ++ +P+ + TP HIA +GN +V+ L + P N +T T LH+A + E+S+ L+E+ K K PLH A+ G +++ L K N G TPL A H + LL++
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLS----------KMENV-------NLDD-------YPDDS-------GWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVE 195 HSP 8 Score: 53.1434 bits (126), Expect = 8.938e-8 Identity = 43/159 (27.04%), Postives = 65/159 (40.88%), Query Frame = 2
Query: 1217 NGFTPLHIACKKIQSKMVELLI--KYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADP-NMVTKDNYTALHIAAKEGRHEISRLLLE 1684
+G+TP HIAC ++V+ L K +N T G+T LH+A E+ L++NGAS+ + + NQ PLH A +G+ ++E L G N K +T L A EG + + LL+E
Sbjct: 71 SGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASV----------------------------------RIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVE 195
BLAST of Ankyrin-2 vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374]) HSP 1 Score: 75.0998 bits (183), Expect = 7.107e-14 Identity = 94/349 (26.93%), Postives = 152/349 (43.55%), Query Frame = 2
Query: 230 NANGLNAMHLAAKEGNREVVQLLIENG-LSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGF--TPLYMAAQENHLDVVKVLLEYGANQAITTDDG---FTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLT-ALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKI 1255
++ G + +A +G +VV+ +IE G ++ GNT+LH A+L G +E+V LL+E+ A++N+KS F TPL A+ HLDVVK LL+ GA+ I G F + + +++ +IL + R L IAAKK N A + + +S +G H N K EK AD A N + K +EE ++ +A G + A++ G + +ENG I L + + + ++ + G V+ + D T AL VA G++ ++LL+ + R G T L+ A I
Sbjct: 327 DSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFESVDDESEFDDEEDQKILREIKKR-------LSIAAKK-WTNRAGIH--------NDKSKNGNN-AHTIDQPPFDNTTKAKNEKAADSPSMASN------IDEKAPEEEFYWTDVTSRA--------GKEKLFKASKEGHLPYVGTYVENGGKID------LRSFFESVKCGHEDITSIFLAFGFPVNQTSRDNKTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYAKNSI 638 HSP 2 Score: 64.6994 bits (156), Expect = 1.044e-10 Identity = 39/113 (34.51%), Postives = 65/113 (57.52%), Query Frame = 2
Query: 2102 HQAENGLTALHLAAEKNRTDIVEQLLKTEA-DISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQT--NLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALE 2431
++ G T L +A +K + D+V+++++ DI+ + G TALH A G I+ V++L++ DVN ++ G T L A+ GH+ +V+ LL N D +N +GLTA E
Sbjct: 325 YRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437 HSP 3 Score: 53.1434 bits (126), Expect = 3.929e-7 Identity = 39/115 (33.91%), Postives = 62/115 (53.91%), Query Frame = 2
Query: 1907 LYKN--GYTPLHLVAKKNMIEVTKLLIDRGA-NVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAEN--GLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHT 2236
+Y++ G T L + K +V K +I+ G ++N Q G T LH ++ G+ EI+ELL++ ADVN ++ G T L A+ D+V+ LLK AD + + G TA +
Sbjct: 324 IYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFES 438 HSP 4 Score: 49.6766 bits (117), Expect = 4.013e-6 Identity = 33/105 (31.43%), Postives = 53/105 (50.48%), Query Frame = 2
Query: 1718 GFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVN--CLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFT 2026
G T L IA G+ V ++++ + N + G T LH A H E++ELL++ A+VN + G TPL + ++V K L+ GA+ ++ KG T
Sbjct: 330 GRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLT 434
BLAST of Ankyrin-2 vs. Ensembl Yeast
Match: AKR1 (Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]) HSP 1 Score: 74.3294 bits (181), Expect = 1.067e-13 Identity = 73/234 (31.20%), Postives = 111/234 (47.44%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGL---SVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQN-GFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGN---------DKVVQILLDNDSRS-KVRLPALHIAAKKDDVNAASLL-IGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADV 805
A L+A RSGN E+ Q + + L H A + G+ V+ +I L + D + + T LH AS+ +L VV L+ A++N ++ TPL+ AA+ ++ +V LL++GA+ +T D GF L +++ N + V + LLD D R K R L A + D + A LL G+S D + GFTPLH +V K LI+ AD
Sbjct: 44 ASLKAIRSGNEEESGN-EQVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTE---GFTPLHWGTVKGQPHVLKYLIQDGADF 273 HSP 2 Score: 70.0922 bits (170), Expect = 2.576e-12 Identity = 60/195 (30.77%), Postives = 94/195 (48.21%), Query Frame = 2
Query: 782 LIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGL---SPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQA----EVCKTLINKGI-DVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIA 1342
L+E N D + + +IT LH A+ + ++ L+SQ A+VN+ R G +P+H AAR G+ I+ LL++GAD G L ++ V +++KG+ D+D T+L AA+ G+ LLK ++ GFTPLH K Q +++ LI+ A T+TG IA
Sbjct: 97 LLEVNNDGD--STEHITGLHWASINNRLSVVDFLVSQGADVNA--RAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIA 287 HSP 3 Score: 68.5514 bits (166), Expect = 6.456e-12 Identity = 59/227 (25.99%), Postives = 103/227 (45.37%), Query Frame = 2
Query: 1724 TPLHIASKYGRVQVARQL----LLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGY---TPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGN-KEIMELLLDANA----DVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVR 2368
T H A + G + +++ LL + +S H +T LH A+ N +++ L+ A+VN + G TPLH A+ + + L+ GA+ +GF LHL+ + N ++ +L + + D++ + G T+L AA + + V +LLK A I G+T LH GQ +K L+Q D +T+ G +A + + +R
Sbjct: 75 TRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEH--ITGLHWASINNRLSVVDFLVSQGADVNA--RAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLR 297 HSP 4 Score: 65.0846 bits (157), Expect = 7.801e-11 Identity = 47/138 (34.06%), Postives = 69/138 (50.00%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLS---VDIATR--KGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVA 559
AAR G V V L+ P M++ G N +HL+ N +V ++ N +S +DI R KG TSL A+ G V+ LL+ A+I + GFTPL+ + V+K L++ GA+ TD G A+A
Sbjct: 150 AARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIA 287 HSP 5 Score: 63.929 bits (154), Expect = 1.540e-10 Identity = 57/236 (24.15%), Postives = 100/236 (42.37%), Query Frame = 2
Query: 1490 EANFNARARENQ--TPLHIAVRMGNYSIVEQ-----LLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGF---TPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNH-----YEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKN 2152
+ N N A E+ T H A + G+ + V++ LL D + + ++ T LH A+ R + L+ D + G TPLH A++YG V + LL +P G LH++ ++ Y + ++ +++C G T L A + L+ GA++ +GFTPLH ++ G +++ L+ AD + + G +A E N
Sbjct: 61 QVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIHGKLLEVNNDGD--STEHITGLHWASINNRLSVVDFLVSQGA--DVNARAGALHATPLHWAARYGYVYIV-DFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMN 291 HSP 6 Score: 59.6918 bits (143), Expect = 3.957e-9 Identity = 66/259 (25.48%), Postives = 107/259 (41.31%), Query Frame = 2
Query: 1025 LTALQMATQ-GDQAEVCKTLINKGIDV--DAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEA----NFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLL 1780
LT A Q GD A V + + K ++V D + +++T LH A+ ++ + L+ +VNARA LH TPLH AA G IV+ LLK+GA + T + N LHL+ ++ +L + + + + R + +T L A G+ V +LL GA + + +T LH +G+ + + L++ KT G IA + V R+ L
Sbjct: 74 LTRYHTACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARA----GALHA----------------------------TPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTVYSLREAL 300 HSP 7 Score: 51.6026 bits (122), Expect = 1.039e-6 Identity = 48/175 (27.43%), Postives = 69/175 (39.43%), Query Frame = 2
Query: 596 LDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLL----ISQKANVNSVTRD--GLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDV 1102
++ND S + LH A+ + ++ L+ D A TPLH AA Y V + L++ AD LH++ ML L + K ++ RD G + + AA G + LL+ GA I+ G T L T Q V K LI G D
Sbjct: 100 VNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVN-SSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADF 273
BLAST of Ankyrin-2 vs. Ensembl Yeast
Match: GDE1 (Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes [Source:SGD;Acc:S000006031]) HSP 1 Score: 70.8626 bits (172), Expect = 1.520e-12 Identity = 55/195 (28.21%), Postives = 91/195 (46.67%), Query Frame = 2
Query: 1226 TPLHIACKKIQSKMVELLIKYKAHINSTTET------------GLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARE-NQTPLHIAVRMGNYSIVEQLLNAGADPNMVTK-DNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVA 1768
TPLH +C+ S++ +L+IK N E LTPLH+ + +LL++ +K + LHLA N +LL + N + E ++TPL++A R+ + LL GAD + K +TA+ +AA EG +I +LL+ + D + + G+TP+ A G + +A
Sbjct: 430 TPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDP--NVKLKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIA 622 HSP 2 Score: 55.8398 bits (133), Expect = 5.891e-8 Identity = 62/244 (25.41%), Postives = 106/244 (43.44%), Query Frame = 2
Query: 1598 PNMVTKDNY--TALHIAAKEGRHEISRLLLE--------HQCKPDAKTKKG----FTPLHIASKYGRVQVARQLLLSAKVNPN-SLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGY---TPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKML 2275
P + DNY T LH + + G E+++L+++ ++ D + G TPLH+ + LL S ++PN L L LH+AT +N+Y ++ +LL ++ + Y++ TPL+L + N E L+ GA++ EI E L G TA+ +AA + TDIV+ L+ A+ + + G+T + AV G + M+
Sbjct: 419 PCLFQHDNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQS--LDPNVKLKSSSL--LHLATEWNNYPLLHVLLSSK-RFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADL--------------------EIREKLF------------GWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMV 625 HSP 3 Score: 51.9878 bits (123), Expect = 8.066e-7 Identity = 56/213 (26.29%), Postives = 96/213 (45.07%), Query Frame = 2
Query: 1826 TPLHVATYYNHYEMIELLLDTEANVNCLYK------------NGYTPLHLVAKKNMIEVTKLLIDR-GANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANA-DVNHQAENGL--TALHLAAEKNRTDIVEQLLKTEADISTKTQM-GYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQ 2413
TPLH + Y E+ +L++ N + TPLHL + T++L+ NV +S + LHL + N ++ +LL + D+N+Q +N L T L+LA N + LL AD+ + ++ G+TA+ A G VK+L+ N + + + G T + A +GH+ I ++ + V H + Q
Sbjct: 430 TPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSS---SLLHLATEWNNYPLLHVLLSSKRFDINYQ-DNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMVQIRDELVTHPHSQ 638 HSP 4 Score: 50.8322 bits (120), Expect = 2.041e-6 Identity = 46/199 (23.12%), Postives = 92/199 (46.23%), Query Frame = 2
Query: 1523 QTPLHIAVRMGNYSIVEQLLNAGADPNMVTK------------DNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHH-GLTPLHVATYYNHYEMIELLLDTEANVNCLYK-NGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELL 2077
+TPLH + + G + + ++ + N+ + ++ T LH+ G H + +L P+ K K + LH+A+++ + LL S + + N + TPL++A N +E LL A++ K G+T + + A + ++ KLLI AN + + + G+TP+ + G+ I +++
Sbjct: 429 RTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVL-GAHPKTTEVLLQSLDPNVKLKSS-SLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMV 625 HSP 5 Score: 48.9062 bits (115), Expect = 7.300e-6 Identity = 50/199 (25.13%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 830 TPLHVAAKWGKEEMLKLLIS--QKANV-NSVTRD---------GLSPIHCAARSGFENIILILLEN-GADIQHKSKNGLTALQMATQGDQAEVCKTLIN-KGIDVDAVTMD-YLTALHVAAHCGNINAAEVLLKNNCNVNAR-ALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNIL 1378
TPLH + ++G E+ KL+I ++ N+ N + D L+P+H +LL++ +++ KS + L +AT+ + + L++ K D++ + + T L++A AA LL N ++ R L G+T + +A + + +V+LLI A+ + E G TP+ A G I +++
Sbjct: 430 TPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSS---SLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMV 625
BLAST of Ankyrin-2 vs. Ensembl Yeast
Match: AVO2 (Component of a complex containing the Tor2p kinase and other proteins; complex may have a role in regulation of cell growth [Source:SGD;Acc:S000004672]) HSP 1 Score: 68.1662 bits (165), Expect = 5.244e-12 Identity = 50/163 (30.67%), Postives = 83/163 (50.92%), Query Frame = 2
Query: 1514 RENQTPLHIAVRMGNYSIVEQLLNAGAD--PNMVTKDNYTALHIAAKEGRHEISRLLLE--HQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRG 1990
+E L A+ GN IV++LL D N+ +++ +++LH A+ GR+ I L++ H KT KG T +H+A G Q LL N G +G P+H+A ++Y+ + LL+ A++ + NG TPLH+ + I K+L++ G
Sbjct: 3 KEPSVRLREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEG 165 HSP 2 Score: 67.0106 bits (162), Expect = 1.039e-11 Identity = 47/162 (29.01%), Postives = 85/162 (52.47%), Query Frame = 2
Query: 131 LTEKAHAFLRAARSGNVEKVKEFLQ--ADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVD--IATRKGNTSLHIASLAGKLEVVSLLLESKAN-INVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLD 601
L E + A GN+ VK L+ D+ ++ + NG +++H A+ G + LI+ G I T KGNT +H+A + G + + LLL+ IN + +NG P+++A ++ + +L+ GA+ + +G TPL V L+ G+ +++LL+
Sbjct: 2 LKEPSVRLREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLN 163 HSP 3 Score: 57.3806 bits (137), Expect = 1.288e-8 Identity = 37/127 (29.13%), Postives = 63/127 (49.61%), Query Frame = 2
Query: 1913 KNGYTPLHLVAKKNMIEVTKLLIDRGANVNA--QSQKGFTPLHLNSMAGNKEIMELLLDANAD-VNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQK 2284
+NG++ LH + + LI G + + ++ KG T +HL M G+++ + LLL +NH+ ENG +H+A + + L+ AD+ G T LH + +G I +KMLL +
Sbjct: 38 ENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNE 164 HSP 4 Score: 52.7582 bits (125), Expect = 2.866e-7 Identity = 44/176 (25.00%), Postives = 74/176 (42.05%), Query Frame = 2
Query: 1301 NSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQ--TTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLL---EHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLG 1813
N +E G + LH A++ G I L++ G + T K +HLA E+T +LL N R + P+HIA Y + L+ GAD ++ + T LH+ + G ++LL E + + K + P+ +A + + ++L K LG
Sbjct: 34 NIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKKKGPPLG 209 HSP 5 Score: 52.7582 bits (125), Expect = 3.179e-7 Identity = 45/185 (24.32%), Postives = 82/185 (44.32%), Query Frame = 2
Query: 350 LHIASLAGKLEVVSLLLESKANI--NVKSQNGFTPLYMAAQENHLDVVKVLLEYG--ANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQ 892
L A + G L +V LL ++ N+ S+NG++ L+ A+ + L++ G ++ I T G T + +AL +G+++ + +LL R ++H+ +G P+HIA + LLI AD+ N TPLHV ++G +K+L+++
Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRF-----------------------------INHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNE 164 HSP 6 Score: 51.9878 bits (123), Expect = 6.134e-7 Identity = 40/129 (31.01%), Postives = 60/129 (46.51%), Query Frame = 2
Query: 1013 SKNGLTALQMATQGDQAEVCKTLINKGIDVDAV--TMDYLTALHVAAHCGNINAAEVLLKNNCN-VNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNG 1390
S+NG ++L A+ + +C LI G D + T T +H+A G+ +LL+ +N R NG P+HIAC + + LLI A + G TPLH+ GS + +LL G
Sbjct: 37 SENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEG 165 HSP 7 Score: 48.521 bits (114), Expect = 6.945e-6 Identity = 43/169 (25.44%), Postives = 79/169 (46.75%), Query Frame = 2
Query: 761 NVNVAKLLIEKNADV--NFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSV--TRDGLSPIHCAARSGFENIILILLENGAD-IQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKN---NCNVNARALNGFTPLHIA 1243
N+ + K L+ +N D+ N ++N + LH A+ G+ + LI + + + T G + +H A G E + +LL+ I H+ +NG + +A D + LI G D+ + + T LHV G+I+ ++LL + + N R + P+ +A
Sbjct: 17 NLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVA 185
BLAST of Ankyrin-2 vs. Ensembl Nematostella
Match: EDO45487 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSW5]) HSP 1 Score: 256.914 bits (655), Expect = 4.731e-75 Identity = 161/455 (35.38%), Postives = 242/455 (53.19%), Query Frame = 1
Query: 2827 MELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGA-SWKEHTNLFTDIAVQDALG-------------NLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-DANRSIPYTVQTSSLRLLCSI-------SGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCR-RKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYAR 4122
M++D+V L + PV GFL+SF+VDA+ G M++ + I+I +P S PTRI C L R LP L + EALACR++ + S P+ LE+P+ AALR GERE+VV+K+D+G +W E ++V+D G E+ + +R R +I T +LP+ F+++SR+K+++ +G+ G ++ S+V VQ PEGA+ K+SLQ+ + N V +SP+VTLEP F + +T+T+P P +S +N I SLRLLC S Q W+DITG +PLT+ SFT AR WLI+ + + A +Y + VP++ +F+VF + + E ++R CITDD +KTLE Q F I+ VEV + + GN+ P+ + L L F+ENRLS R
Sbjct: 1 MQVDNVPLYEPPVTGGFLVSFLVDARSGKMESTQT-GIKIVLPPRSCQMPTRITCRLLRINRPTLLPPLREGEALACRVLDIGPSGTRFLQPVYLEVPYFAALRDGERELVVMKTDDGGWNWDE-------VSVEDMKGKCHAICLKIERVKGYKEDSPDAIFPSR-RYAKISTQALPERFAVVSRVKKEIFSVGSRGESIRSAVLPSVQVNVPEGAVASGTKMSLQVQPVDENF--NNLEEWVTVSPVVTLEPADIIFKKPVTVTIPCPVYSGQSNPDI-----QPSLRLLCCFPKEAKAGSAQTPAYQWQDITGNTPLTVIGANASFTIDRPARYWLIETRNPDNVTADARLIYRKLAAVPYLAKFVVFAKLSADGTEARLRVFCITDDKMDKTLEGQTGFVEIARSRDVEVHDGRPIHIRCLGNLAPVQR--DPLHLNFFSFRENRLSVTVR 437
BLAST of Ankyrin-2 vs. Ensembl Nematostella
Match: EDO45486 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSW2]) HSP 1 Score: 163.31 bits (412), Expect = 1.523e-44 Identity = 100/288 (34.72%), Postives = 151/288 (52.43%), Query Frame = 1
Query: 3286 RIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWS-DANRSIPYTVQTSSLRLLCSI-------SGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCR-RKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYAR 4122
R +I T +LP+ F+++SR+K+++ +G+ G ++ S+V VQ PEGA+ K+SLQ+ + N V +SP+VTLEP F + +T+T+P P +S +N I SLRLLC S Q W+DITG +PLT+ SFT AR WLI+ + + A +Y + VP++ +F+VF + + E ++R CITDD +KTLE Q F I+ VEV + + GN+ P+ + L L F+ENRLS R
Sbjct: 11 RYAKISTQALPERFAVVSRVKKEIFSVGSRGESIRSAVLPSVQVNVPEGAVASGTKMSLQVQPVDENF--NNLEEWVTVSPVVTLEPADIIFKKPVTVTIPCPVYSGQSNPDI-----QPSLRLLCCFPKEAKAGSAQTPAYQWQDITGNTPLTVIGANASFTIDRPARYWLIETRNPDNVTADARLIYRKLAAVPYLAKFVVFAKLSADGTEARLRVFCITDDKMDKTLEGQTGFVEIARSRDVEVHDGRPIHIRCLGNLAPVQR--DPLHLNFFSFRENRLSVTVR 289
BLAST of Ankyrin-2 vs. Ensembl Nematostella
Match: EDO38702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC57]) HSP 1 Score: 124.405 bits (311), Expect = 1.168e-29 Identity = 125/488 (25.61%), Postives = 209/488 (42.83%), Query Frame = 2
Query: 728 FTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALH----VAAHC--GNINAAEVLLKNNCN---VNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDI 2164
TPLH+A + + VAK L+E AD+ + +TPLH A G + KLL + R G+ + ++ + + Q TAL +A +G ++ K + KG +V+AV H VA C I +++ + C + L F + I ++ +I+++A I + TPL IAA + V LL++GA I+ + N++ AA ET + L E+Q P+ ++I + + G +V N L + S+LLL++ D+K + TP+H A+K+GRV+ LL N TPLH+A + H +++ LL ++ +TPL A + M+EV +L+D A V+ + TPLHL S G+ E+++LLL A++ G L +A E + ++
Sbjct: 5 MTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLF----------------VAAELRGGWSTVSKMVTDQDREEQ-------TALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVI--------IICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAAL------------EHQKPV--------WTICDDVCLNG----LVGGSNKLILVLRIS------SQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEV 431 HSP 2 Score: 102.064 bits (253), Expect = 2.513e-22 Identity = 122/493 (24.75%), Postives = 211/493 (42.80%), Query Frame = 2
Query: 440 FTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAK-KDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILIL---LENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNN------CN-VNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLD 1885
TPL++A + V K L+E GA+ ++ TPL A +GN V ++L +AA+ + + S ++ +D + + Q+A LH+A + ++AKL +EK A+VN ++ H +E + ++ K S + I F ++++I+ + A I+ + K+ T L +A + + + +TL+ G D+ A ++ ++ AA G + E L++ C+ V L G + I +I S +LL+ A I+S + +TP+H AA G V LLK +I N + TPLH+A G+ ++V++LL G + +T L AA G E++ +LL+ D K TPLH+AS+ G V++ + LLLS K N G L +A +H E+ ++D
Sbjct: 5 MTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLF--------------VAAELRGGWSTVSKMV--TDQDREEQTA-----LHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKS--EKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISS---QLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAI---------------------------------INDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVK-LLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIID 437 HSP 3 Score: 98.2117 bits (243), Expect = 4.153e-21 Identity = 107/434 (24.65%), Postives = 182/434 (41.94%), Query Frame = 2
Query: 1016 KNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGF---------------TPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLL-----HPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRV----QVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTE-ANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAV 2242
K +T L +A V K L+ G D+ ++ + +T LH A GN+ A++L V A G+ T LH+A + + +L ++ A++N+ E+ H + ++E + +++K + K E R F ++++ A R ++ TPL IA + V LL GAD ++ ++ AA EG E LEHQ KP + ++ +++ QLLL +S +TP+H A + + LL + A +N TPLHL A V K L+ RG ++A++ +TPL + G E+ +LLD +A V+ + T LHLA+ + ++V+ LL +A+I+ G L A+
Sbjct: 2 KTQMTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLF-----VAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFH-KTIVVARECIFVMIKVSKLKYLSFCKSEKI----KREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQ-KPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAI 424 HSP 4 Score: 95.5153 bits (236), Expect = 3.872e-20 Identity = 107/443 (24.15%), Postives = 185/443 (41.76%), Query Frame = 2
Query: 1223 FTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNIL-----LKNGAS-----ISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHE---------ISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLL-SAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVN------CL--YKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGN-KEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIA 2464
TPLH+AC + + L++ A + S E +TPLH A G+ + +L L+ G S ++ + + ALHLA + K L L AN NA H + + I + V+K Y + + K R I ++ + + + K TPL IA++ V R LL A + + + A E +E L+ + V CL G L LV + + ++LL+D GA +++++ + TP+H + G + + LL A +N + T LHLAA +V++LL I + +T L A G ++ +LL ++ V+ T LHLA+++GH+ +V+LLL + ++ + G L++A + + +A
Sbjct: 5 MTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAK-LCLEKGANVNAVKESKNKTFHKTIVVARECIFVMI--------KVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDR--NSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRIS----SQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVA 432 HSP 5 Score: 87.0409 bits (214), Expect = 1.934e-17 Identity = 79/356 (22.19%), Postives = 148/356 (41.57%), Query Frame = 2
Query: 245 NAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGK----------------------------------LEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAI------------TTDDGFTPLAVALQQ------------------GNDKVV-------QILLDN----DSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLIN 1087
A+HLA + G+ ++ +L +E G +V+ N + H + + + ++ ++ +A I + ++ TPL +AA++NH+D V+ LL++GA+ A + L AL+ G++K++ Q+LLDN DS++ + +H AAK V L+ ++ + + TPLH+AA + + V K L+ + ++ TPL AA G E+ +L+ + A V+ + +P+H A+R G ++ +LL A+I G L +A + EV +I+
Sbjct: 82 TALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIID 437 HSP 6 Score: 84.3445 bits (207), Expect = 1.140e-16 Identity = 114/451 (25.28%), Postives = 190/451 (42.13%), Query Frame = 2
Query: 242 LNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLL--------ESKANINVKSQNGF--TPLYMAAQENHLDVVKVLLEYGAN-QAI--TTDDGFTPLAVALQQGNDKVVQIL-LDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRD----GLSPIHCAARSGFENIILIL-------LENGADIQHKSKNGLTALQMATQ-GDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARAR 1516
+ +H+A G V + L+E G + + T LH A + G L V LL S + V Q+ T L++A + H D+ K+ LE GAN A+ + + F V ++ ++++ L S K I DV I ++ + TPL IAA N+V+ + L++ AD+ N+ + AA G E L+ + + V ++ D GL G +IL+L L+NGA I K+ +T + A + G VC L ++ T LH+AA G+ + LL ++AR +TPL A + ++ +L+ A ++ T + TPLH+A+ G E+V +LL A+I+ T N L +A ++ +E ++ H + R R
Sbjct: 5 MTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLV-------GGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDHVDWKQAMRNR 448 HSP 7 Score: 66.6254 bits (161), Expect = 4.435e-11 Identity = 49/158 (31.01%), Postives = 85/158 (53.80%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQAD--IKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDN-DSRSKVR 625
AA+ G V V L+ D I D A+ +HLAA G+ VV+ L+ G ++D T L A+ G +EV ++LL+ A ++ + TPL++A++E H+++VK+LL AN +T G L +A++ + +V ++D+ D + +R
Sbjct: 290 AAKFGRVRTVCALLKRDPAIINDEDGASN-TPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDHVDWKQAMR 446
BLAST of Ankyrin-2 vs. Ensembl Nematostella
Match: EDO43690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXV8]) HSP 1 Score: 105.916 bits (263), Expect = 9.556e-25 Identity = 77/242 (31.82%), Postives = 129/242 (53.31%), Query Frame = 2
Query: 152 FLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQG---NDKVVQILLD----NDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKW 856
FL A SG+V++VK+ L + N +GL A+H A + N ++V++L++ G S+D+ +G TSLH A+ G +E+ L+E+ A++ + G PL +A +E+ D++ +E NQ I DD A A+++ ND Q L+ N+S+ K ALH+A+ K + LL+ + ++ + A +TPLH AAH+ + +LL E AD F A+N + + W
Sbjct: 53 FLSAVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEEDMEDLLTDEIE---NQGIDVDD-----ARAVEEKIMLND--AQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVE-INAKDADNWTPLHAAAHWGQKDACELLSENGAD--FNARNKMVGIDHQQNW 281 HSP 2 Score: 89.7373 bits (221), Expect = 3.038e-19 Identity = 70/233 (30.04%), Postives = 112/233 (48.07%), Query Frame = 2
Query: 713 QSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLI-NKGIDVD---AVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASI 1399
Q SG L A +V+ K L+ K AD+N+ + +T LH A +++K+L+ + A+++ +G + +H AA G I L+ENGAD+ + G L +A + D ++ I N+GIDVD AV + +N A+ L NC ++ + LH+A K K++ LL++ IN+ TPLH AA G K+ +L +NGA
Sbjct: 46 QFNSGIVFLS-AVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEEDMEDLLTDEIENQGIDVDDARAVEEKIM-----------LNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADF 266 HSP 3 Score: 83.5741 bits (205), Expect = 3.859e-17 Identity = 71/245 (28.98%), Postives = 113/245 (46.12%), Query Frame = 2
Query: 1694 KPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDA------NADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNK 2410
KP + G L S +V + L A +N ++ GLT LH A +++++++L+D A+++ G+T LH A +E+ K LI+ GA+V A + +G PL L A +++ +LL D + D E + + N+ I E KTEA +ALH A G ++ + +LLQ ++NA+ T LH AA G LL +N D N +NK
Sbjct: 42 KPKIQFNSGIVFLSAVSSGDVDEVKKLLAKGADINYQNV--DGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDL---AEEEDMEDLLTDEIENQGIDVDDARAVEEKIMLNDAQSWLNKNCINESKDKTEA----------SALHVASSKGYLKVIGLLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADFNARNK 271 HSP 4 Score: 80.1073 bits (196), Expect = 5.802e-16 Identity = 58/216 (26.85%), Postives = 97/216 (44.91%), Query Frame = 2
Query: 1142 AAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETF-------------------KILLLHPEANFN------ARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTK 1714
A G+++ + LL ++N + ++G T LH AC +V++L+ A ++ G T LH AA GS EI L++NGA ++ + E L LA + E+ KI+L ++ N ++ + + LH+A G ++ LL G + N DN+T LH AA G+ + LL E+ +A+ K
Sbjct: 56 AVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEEDMEDLLTDEIENQGIDVDDARAVEEKIMLNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADFNARNK 271 HSP 5 Score: 78.5666 bits (192), Expect = 1.906e-15 Identity = 60/216 (27.78%), Postives = 100/216 (46.30%), Query Frame = 2
Query: 1541 AVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLD-------------------------TEANVNCLY----KNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVN 2101
AV G+ V++LL GAD N D TALH A + ++ ++L++ D + +G+T LH A+ G V++A+ L+ + + ++ + G PL +A +M +LL D + N NC+ K + LH+ + K ++V LL+ G +NA+ +TPLH + G K+ ELL + AD N
Sbjct: 56 AVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENG-ADVAAVNNEGELPLDLAE---EEDMEDLLTDEIENQGIDVDDARAVEEKIMLNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADFN 267 HSP 6 Score: 75.485 bits (184), Expect = 1.594e-14 Identity = 71/231 (30.74%), Postives = 108/231 (46.75%), Query Frame = 2
Query: 944 AARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGAS------ISQTTMKCE-NALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTK 1615
A SG + + LL GADI +++ +GLTAL A + ++ K L++KG +D + T+LH AA CG++ A+ L++N +V A G PL +A + M +LL T E + + +E I+L + S I+++ K E +ALH+A+ + LLL NA+ +N TPLH A G E L GAD N K
Sbjct: 56 AVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLA---EEEDMEDLL---------TDEIENQGIDVDDARAVEE--KIMLNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIG-LLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADFNARNK 271 HSP 7 Score: 70.4774 bits (171), Expect = 8.848e-13 Identity = 60/222 (27.03%), Postives = 113/222 (50.90%), Query Frame = 2
Query: 368 AGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDS-----RSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSK 1018
+G ++ V LL A+IN ++ +G T L+ A + + D+VKVL++ GA+ + ++G+T L A G+ ++ + L++N + ++ LP L +A ++D + + I + +VD A + +N A+ + KN K + LHVA+ G +++ LL+ +N+ D +P+H AA G ++ +L ENGAD ++K
Sbjct: 59 SGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELP-LDLAEEEDMEDLLTDEIENQGIDVDDARAVEEKIM--------LNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADFNARNK 271 HSP 8 Score: 57.7658 bits (138), Expect = 1.262e-8 Identity = 36/103 (34.95%), Postives = 55/103 (53.40%), Query Frame = 2
Query: 2138 AAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQ 2446
A D V++LL ADI+ + G TALH A VK+L+ K ++ + N G TSLH AA G + I + L++N DV N +G L++A+++
Sbjct: 56 AVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEE 158
BLAST of Ankyrin-2 vs. Ensembl Nematostella
Match: EDO39113 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB41]) HSP 1 Score: 100.908 bits (250), Expect = 3.956e-24 Identity = 65/185 (35.14%), Postives = 100/185 (54.05%), Query Frame = 2
Query: 1739 ASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGY---TPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLL-DANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQ 2281
A + GR R+LL N N+L G +PLH AT NH +++++LLD A+V+ P+ AK N IE ++L+ GA+VN + G T LH + G+ +++ELLL D DVN + T+LH+AA I++ LL A+I+ K G+TA H A G+ + ++ LL+
Sbjct: 2 ACRDGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLR 186 HSP 2 Score: 88.9669 bits (219), Expect = 5.853e-20 Identity = 56/181 (30.94%), Postives = 93/181 (51.38%), Query Frame = 2
Query: 1154 GNINAAEVLLKNN-CNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHIN---STTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLE 1684
G + LL+ N N+N +GF+PLH A +V++L+ A ++ S + + P+ AA + E +LL+ GA ++ T + ALH A R + ++LL + + N R+N T LH+A +G+ I++ LL GA+ D +TA H+AA+EG E+ + LL
Sbjct: 6 GRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLR 186 HSP 3 Score: 85.1149 bits (209), Expect = 1.128e-18 Identity = 63/214 (29.44%), Postives = 101/214 (47.20%), Query Frame = 2
Query: 359 ASLAGKLEVVSLLLESK-ANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLI-EKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENG 994
A G+ + V LL N+N +GF+PL+ A NH+D+V++LL+ GA+ + S S R+P + AAK + + + +L+ + D V+ + G T LH A + + +LL+ + DVN ++N T LHVAA G ++K L+ AN+ + DG + H AAR G E ++ LL G
Sbjct: 2 ACRDGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDV--------------------------RGSPSIQRIPPIICAAKFNAIESCRVLLRAGAD-VNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188 HSP 4 Score: 81.2629 bits (199), Expect = 2.975e-17 Identity = 55/173 (31.79%), Postives = 92/173 (53.18%), Query Frame = 2
Query: 1871 ELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQ---SQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKT-EADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLL 2377
+LL N+N L +G++PLH N +++ ++L+D GA+V+ + S + P+ + E +LL A ADVN G TALH A + + +VE LL+ + D++ + T+LH A G +K LL ++ A+ N G T+ HLAA++G +++ LL
Sbjct: 13 KLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLL 185 HSP 5 Score: 78.1814 bits (191), Expect = 3.238e-16 Identity = 55/187 (29.41%), Postives = 93/187 (49.73%), Query Frame = 2
Query: 1640 AAKEGRHEISRLLLEHQ-CKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGH---HGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRG-ANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKT 2185
A ++GR + R LL + GF+PLH A+ V + Q+LL A + + G + P+ A +N E +LL A+VN G T LH ++ ++ +LL+ G +VN + T LH+ +M G+ I++ LL A++ + +G TA HLAA + ++++ LL+T
Sbjct: 2 ACRDGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIV-QMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRT 187 HSP 6 Score: 78.1814 bits (191), Expect = 3.495e-16 Identity = 55/187 (29.41%), Postives = 97/187 (51.87%), Query Frame = 2
Query: 845 AAKWGKEEML-KLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHK---SKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNN-CNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNG 1390
A + G+++ + KLL N+N++ DG SP+H A + +I+ +LL+ GAD+ + S + + A + + E C+ L+ G DV+ TALH A G+ E+LL++ +VN + T LH+A + +++ L+ A+I + G T H+AA G +E++ LL+ G
Sbjct: 2 ACRDGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188 HSP 7 Score: 77.411 bits (189), Expect = 5.920e-16 Identity = 55/176 (31.25%), Postives = 89/176 (50.57%), Query Frame = 2
Query: 1964 VTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALH---LAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKN-FDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
V KLL N+N GF+PLH + + +I+++LLDA ADV+ + + + AA+ N + LL+ AD++ G TALH A G + V++LL+ DVN TSLH+AA G I++ LL ++ ++ G TA +A ++ + +TL +
Sbjct: 11 VRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLR 186 HSP 8 Score: 76.2554 bits (186), Expect = 1.388e-15 Identity = 39/117 (33.33%), Postives = 69/117 (58.97%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENG-LSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYG 508
AA+ +E + L+A +++N G A+H A + G+ ++V+LL+ +G + V++ R TSLH+A++ G ++ LL ANI K +GFT ++AA+E +V++ LL G
Sbjct: 72 AAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188 HSP 9 Score: 75.8702 bits (185), Expect = 1.798e-15 Identity = 55/199 (27.64%), Postives = 97/199 (48.74%), Query Frame = 2
Query: 701 NVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNF---PAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKG-IDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIK 1285
N++ A GF+PLH A N+V++ ++L++ ADV+ P+ I P+ AAK+ E + +LL GAD+ + G TAL AT+ +++ + L+ G +DV+ V D T+LHVAA G+ + LL N+ A+ +GFT H+A ++ + ++++ L++
Sbjct: 21 NLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCR---------------------------------VLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLR 186 HSP 10 Score: 67.781 bits (164), Expect = 1.140e-12 Identity = 53/187 (28.34%), Postives = 86/187 (45.99%), Query Frame = 2
Query: 1439 AARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALH---IAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRG 1990
A R+ +++ + LL N N + +PLH A + IV+ LL+AGAD ++ + + AAK E R+LL + G T LH A++ G ++ LL +++ N + T LHVA +I+ LL AN+ +G+T HL A++ EV + L+ G
Sbjct: 2 ACRDGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188 HSP 11 Score: 61.6178 bits (148), Expect = 1.537e-10 Identity = 46/150 (30.67%), Postives = 79/150 (52.67%), Query Frame = 2
Query: 161 AARSGNVEKVKEFLQADIKPDMSNANGLNAMH---LAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLL-ESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILL 598
A + +V+ V+ L A D+ + + + AAK E ++L+ G V+I G T+LH A+ G ++V LLL + + ++NV ++ T L++AA ++K LL GAN +DGFT +A ++G ++V+Q LL
Sbjct: 36 ATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLL 185
BLAST of Ankyrin-2 vs. Ensembl Medaka
Match: ENSORLT00000039458.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458]) HSP 1 Score: 801.971 bits (2070), Expect = 0.000e+0 Identity = 416/803 (51.81%), Postives = 566/803 (70.49%), Query Frame = 2
Query: 149 AFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
+FLRAAR+GN++KV E+L+ + N NGLNA+HLAAKEG+ ++VQ L++ G VD +T+KGNT+LHI+SLAG+ EVV L++ A+IN +SQNGFTPLYMAAQENHLDVV+ LLE G NQ+ T+DGFTPLA+ALQQG+++VV ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M++LL+ + + +++ TRDGL+P+HCAARSG E + +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS + ++ E +LH+AAR Q E + LL + A +ARARE+QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ E + +LLE TKKGFTPLH+ SKYG + VA+ LLL + P+S G +GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ +L+ GA NA +++G TPLHL S G+ ++ LL+ A +N ++GLTALHLAA+++R + E L++ A++ +T++GYT L A H+G + V LLQ VNA+T G T LH AAQQG+ I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 35 SFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRN-GAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAK-LLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYISVVDTLRVVTEEVVTTTTTVTEKHKLNVPETMTE 834 HSP 2 Score: 444.121 bits (1141), Expect = 4.471e-128 Identity = 244/633 (38.55%), Postives = 358/633 (56.56%), Query Frame = 1
Query: 2833 LDSVQLIQRPVRAG-----------FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV---KTCIHDISIVDESERKFAE 4683
LD+V L PV +G FL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T+P + + E LA R+I + S GP+++EIPH A+LR ERE+V+L+S+ G SWKEH T + L + E++ T E R RI RIIT PQYF+ +SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ + N+++K GN SPIVTLEPRRRKFH+ IT+T+P+P + + T +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E + ++ +Y E VP++ +F++F + + E ++RC C+TDD +KTLE QENF ++ VEVLE + + GN++P+T S + F+ENRL+ + +I+D + PCG+++FM++PR + L Q IC L+ITLP+ + L +D P ++ E K E + +A +G W +L +LG +E+I I ++ + D+++ L W ++ Q + L L I R DIV +T ++ + D S +AE
Sbjct: 940 LDNVALSSSPVHSGRCSPCHGDHSSFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCSAPTRITCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFASLRGRERELVILRSETGESWKEHHCEHTQEELNQILNGMDEDLDTPEELERKRICRIITRDFPQYFAAVSRIKQDSHLIGPEGGILSSTVVPQVQAVFPEGALTKRIRVGLQAQPVSVNVVRKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPGSNSDPVLNGFGGYTPTLRLLCSITGGTTPAQWEDITGTTPLTFINDCVSFTTNVSARFWLIDCRQVQESINFSTQVYREIICVPYMAKFVIFAKTHDPIEARLRCFCMTDDKIDKTLEQQENFTEVARSRDVEVLEGKPIYADCFGNLVPLTKSGQHHLFSFYAFKENRLALFIKIRDNTQEPCGRLSFMKEPRN---------------YRALTQNAICNLNITLPSYSKVSRTLEKLD----------PQEEAE-------KREQRLAVIADHLGFSWTELARDLGFSEEKINTIRNENPNSLLDQSHALLNQW--AQREAQHATAEATLVKQLTKINRMDIVHLIETGLNRSTQEDTSSHTYAE 1538 HSP 3 Score: 340.502 bits (872), Expect = 2.062e-94 Identity = 244/775 (31.48%), Postives = 392/775 (50.58%), Query Frame = 2
Query: 119 TKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDS----RSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGN-----------------------------KEIMELLLDANAD--------------------------VNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTV 2266
T+D T A A + G+ + V L+ D K + L A+H+AA++ + + LL++N + D+ ++ G T LHIA+ G + V +LLL A ++ ++NG TPL++A++ + ++V++LL+ G+ T DG TPL A + G++ V++LL+ + R+K L LH+AA+ D V L+ VD + T LH+AAH + V KLL++K A+ N A N TPLH+A K + ++++LL+ A++ +VT GL+PIH AA G NI+L+LL+NGA + G T+L MA + QAEV + L+ G VDA + T LH+A+ G ++LL++ + +A NG+TPLHI+ ++ Q + +L++ A + T+ G TPLH+ + GS ++ +LL+ A LH+AA + ++ +LLL A+ + A+ TPLHIA + I LL GA+ N +TK T LH+A++EG +++ LL+ + + TK G T LH+A++ RV VA ++L+ N + G TPL VA +Y + +M+ LL A+VN KNGYTPLH A++ + +L+ GA NA + G T L + G E M +LD + + + Q +G+ LH + E RTD E+ T T GY ++ H G ++ V
Sbjct: 161 TEDGFTPLAIAL----QQGHNQVVSILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLL-QHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQK-VALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVA-EILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYISVVDTLRVVTEEVVTTTTTVTEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLRELGDDSLPGQYLDGMNYLHFSLEGGRTDSAERSF-------TPTHHGY---YSPRHEGVLEDV 914 HSP 4 Score: 245.358 bits (625), Expect = 7.815e-65 Identity = 175/559 (31.31%), Postives = 281/559 (50.27%), Query Frame = 2
Query: 1010 KSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTT--------------------MKCEN---------ALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYG---------------------------------RVQVARQLLL-SAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
KS + + L+ A G+ +V + L G+D+ + L ALH+AA G+++ + LL V++ G T LHI+ Q+++V+ L+K A IN+ ++ G TPL++AA ++V LL+NG + S T + EN ALH+AAR + ++ LLL + N + +++ TPLHIA GN ++ LLN GA + ++ T LH+A+K G + RLLL+ + DAKT+ G TPLH A++ G V+ + LL A V+ +L + LT LHVA + HY + +LLLD AN N NG+TPLH+ KKN ++V +LL+ GA++ A ++ G TP+H+ + G+ I+ LLL A + G T+LH+AA + ++V LL+ A + + + T LH A G+ + V++LLQ +A T G T LH++A++G + +LL+ + K+G T L V K L++A+ L + P+
Sbjct: 29 KSDSNTSFLRAARAGNIDKVLEYL-KGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKS-AALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY--LTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPD 583
BLAST of Ankyrin-2 vs. Ensembl Medaka
Match: ENSORLT00000031565.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458]) HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0 Identity = 417/809 (51.55%), Postives = 569/809 (70.33%), Query Frame = 2
Query: 131 LTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMID 2557
L++ +FLRAAR+GN++KV E+L+ + N NGLNA+HLAAKEG+ ++VQ L++ G VD +T+KGNT+LHI+SLAG+ EVV L++ A+IN +SQNGFTPLYMAAQENHLDVV+ LLE G NQ+ T+DGFTPLA+ALQQG+++VV ILL+ND++ KVRLPALHIAA+KDD +A+LL+ +D N D QS SGFTPLHIAAHY NVNVA LL+ + A V+F A+N ITPLHVA+K G M++LL+ + + +++ TRDGL+P+HCAARSG E + +LLE GA + ++KNGL+ L MA QGD E K L+ VD VT+DYLTALHVAAHCG+ ++LL N NARALNGFTPLHIACKK + K++ELL+KY A I + TE+GLTP+H+AAFMG IV +LL+NGAS + ++ E +LH+AAR Q E + LL + A +ARARE+QTPLHIA R+G IV+ LL A P+ T + YT LHI+A+EG+ E + +LLE TKKGFTPLH+ SKYG + VA+ LLL + P+S G +GLTPLHVA +Y++ ++ LLLD A+ + KNGYTPLH+ AKKN +++ +L+ GA NA +++G TPLHL S G+ ++ LL+ A +N ++GLTALHLAA+++R + E L++ A++ +T++GYT L A H+G + V LLQ VNA+T G T LH AAQQG+ I+ +LL + N G TAL +A++ Y+++ +TL VT + + +K L+ PE M +
Sbjct: 44 LSDSNTSFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLL-QNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRN-GAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAK-LLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYISVVDTLRVVTEEVVTTTTTVTEKHKLNVPETMTE 849 HSP 2 Score: 444.121 bits (1141), Expect = 4.885e-128 Identity = 244/633 (38.55%), Postives = 358/633 (56.56%), Query Frame = 1
Query: 2833 LDSVQLIQRPVRAG-----------FLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPT-KPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIV---KTCIHDISIVDESERKFAE 4683
LD+V L PV +G FL+SF+VDA+GG M+ RH +RI +P PTRI C L ++ T+P + + E LA R+I + S GP+++EIPH A+LR ERE+V+L+S+ G SWKEH T + L + E++ T E R RI RIIT PQYF+ +SR+KQD IG EGG ++S+V QVQAVFPEGAL K+I++ LQ + N+++K GN SPIVTLEPRRRKFH+ IT+T+P+P + + T +LRLLCSI+G TP WEDITGT+PLT + CVSFTT +SAR WLIDC + E + ++ +Y E VP++ +F++F + + E ++RC C+TDD +KTLE QENF ++ VEVLE + + GN++P+T S + F+ENRL+ + +I+D + PCG+++FM++PR + L Q IC L+ITLP+ + L +D P ++ E K E + +A +G W +L +LG +E+I I ++ + D+++ L W ++ Q + L L I R DIV +T ++ + D S +AE
Sbjct: 955 LDNVALSSSPVHSGRCSPCHGDHSSFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCSAPTRITCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFASLRGRERELVILRSETGESWKEHHCEHTQEELNQILNGMDEDLDTPEELERKRICRIITRDFPQYFAAVSRIKQDSHLIGPEGGILSSTVVPQVQAVFPEGALTKRIRVGLQAQPVSVNVVRKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPGSNSDPVLNGFGGYTPTLRLLCSITGGTTPAQWEDITGTTPLTFINDCVSFTTNVSARFWLIDCRQVQESINFSTQVYREIICVPYMAKFVIFAKTHDPIEARLRCFCMTDDKIDKTLEQQENFTEVARSRDVEVLEGKPIYADCFGNLVPLTKSGQHHLFSFYAFKENRLALFIKIRDNTQEPCGRLSFMKEPRN---------------YRALTQNAICNLNITLPSYSKVSRTLEKLD----------PQEEAE-------KREQRLAVIADHLGFSWTELARDLGFSEEKINTIRNENPNSLLDQSHALLNQW--AQREAQHATAEATLVKQLTKINRMDIVHLIETGLNRSTQEDTSSHTYAE 1553 HSP 3 Score: 339.732 bits (870), Expect = 3.936e-94 Identity = 244/775 (31.48%), Postives = 392/775 (50.58%), Query Frame = 2
Query: 119 TKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDS----RSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGN-----------------------------KEIMELLLDANAD--------------------------VNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTV 2266
T+D T A A + G+ + V L+ D K + L A+H+AA++ + + LL++N + D+ ++ G T LHIA+ G + V +LLL A ++ ++NG TPL++A++ + ++V++LL+ G+ T DG TPL A + G++ V++LL+ + R+K L LH+AA+ D V L+ VD + T LH+AAH + V KLL++K A+ N A N TPLH+A K + ++++LL+ A++ +VT GL+PIH AA G NI+L+LL+NGA + G T+L MA + QAEV + L+ G VDA + T LH+A+ G ++LL++ + +A NG+TPLHI+ ++ Q + +L++ A + T+ G TPLH+ + GS ++ +LL+ A LH+AA + ++ +LLL A+ + A+ TPLHIA + I LL GA+ N +TK T LH+A++EG +++ LL+ + + TK G T LH+A++ RV VA ++L+ N + G TPL VA +Y + +M+ LL A+VN KNGYTPLH A++ + +L+ GA NA + G T L + G E M +LD + + + Q +G+ LH + E RTD E+ T T GY ++ H G ++ V
Sbjct: 176 TEDGFTPLAIAL----QQGHNQVVSILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLL-QHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQK-VALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVA-EILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYISVVDTLRVVTEEVVTTTTTVTEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLRELGDDSLPGQYLDGMNYLHFSLEGGRTDSAERSF-------TPTHHGY---YSPRHEGVLEDV 929
BLAST of Ankyrin-2 vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380]) HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0 Identity = 384/783 (49.04%), Postives = 548/783 (69.99%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVT 2485
+ A +FLRAARSGN++K + ++ I +++N NGLN +HLA+KEG+ ++V L+ +G+ ++ T+KGNT+LHIA+LAG+ +VV+ L+ AN+N +S GF+PLYMAAQENHL+VVK LLE GANQ++ T+DGFTPLAVALQQG++ VV +L++ ++ KVRLPALHIAA+ DD A++L+ +D N D S +GFTPLHIAAHY N++VA+LL+ + A+VNF KN ITPLH+A++ G M++LL+ + A +++ T+D L+P+HCAAR+G II ILLE+GA IQ K+KNGL+ + MA QGD + + L+ ++D +T+D+LT LHVAAHCG+ A+VLL NARALNGFTPLHIACKK + ++LL+K+ A + + TE+GLTPLH+AAFMG IV LL+ GAS + + +K E LH+A+R E + LL + A +ARA+++QTPLH A RMG+ +V+ LL+ A+P+ T +T LHIAA+EG R+LL+ + TKKGFTPLH+ASKYG+V VA +LLL NPN+ G +GLTPLHVA ++N+ ++++LL+ + + +NGYTPLH+ AK+N IEV +L+ GA+ N +S +G TPLHL S G +++ +L+ A+VN +NGLT LHL A++ I + L+K A + ++MGYT LH A H+G I+ VK LLQ+ VNA+T +G T LH AAQQGH IV LLL + N G + L +A++ Y+++ + L VT
Sbjct: 9 DAATSFLRAARSGNLDKALDHIKNGININIANQNGLNGLHLASKEGHVKMVLELLHSGIELEATTKKGNTALHIAALAGQEKVVAELVNYGANVNAQSHKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLL-QNDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLLDRGAQIDAQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRGASPNASNVKVETPLHMASRAGHCEVAQFLLQN-AAQVDARAKDDQTPLHCAARMGHKELVKLLLDHKANPDSATTAGHTPLHIAAREGHIHTIRILLDAGAQQVKMTKKGFTPLHVASKYGKVDVA-ELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSAHSTARNGYTPLHIAAKQNQIEVASVLLQNGASPNCESLQGITPLHLASQEGRPDMVAMLISKQANVNLGNKNGLTPLHLVAQEGHVGIADTLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNAKTRMGYTPLHQAAQQGHTDIVTLLLKHGALPNEITSNGTSPLGIAKRLGYISVIDVLKLVT 788 HSP 2 Score: 395.201 bits (1014), Expect = 3.929e-112 Identity = 218/608 (35.86%), Postives = 342/608 (56.25%), Query Frame = 1
Query: 2836 DSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPL-PNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQ-LSLKITPFQENRLSFYARIKDLSNPPCGKVAFM------EDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQS-GTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKT 4632
D+V + P+ GFL+SF+VDA+GG M+ RH +R+ +P + PTRI C L + + T P L + E LA RII L S+ GP+++EIPH A+L +G+RE+VVL+S+NG+ WKEH N + D ++ L + E++++ E + RI+RII+T P YF+++SR++Q+ IG EGG + S + V+A+FPE A+ K++++ LQ I L+ + GN SP+VT+EPRRRKFH I L +PL P+W ++ R T+SLRLLCS+ G P WEDITGT+ L C SFTT +SAR WL DC RT E V A+ LY+E +P++ +F++F + E ++RC C+TDD +KTLE ENF ++ +E++E LE SGN++PI + +Q S F++NRL +++D + G ++F+ ED Q +C L+IT+P P K + ++++ RT+ + L +RE + +L L G ++I RI +++ + D++ L LW +++ +K+ + L +LR+I R DIV +
Sbjct: 884 DNVSPVASPIHTGFLVSFMVDARGGSMRGSRHHGLRVIIPPRTCAAPTRITCRLVKPQKLTTPPPLVEGEGLASRIISLGPSSMQFLGPVIVEIPHFASLGRGDRELVVLRSENGSVWKEHRNRYGDEVLETILNGMDEDLESQEELEKKRIRRIISTDFPLYFAVVSRIQQESDLIGPEGGRLTSKLVPHVEAIFPESAVTKRVRLGLQAQPIPDELLTRQLGNQATFSPVVTIEPRRRKFHRPIGLRIPLPPSWRESPRDAGEG-DTTSLRLLCSVIGGTAPAQWEDITGTTKLMYAHNCASFTTNVSARFWLADCPRTAEAVTFANLLYKELMAIPYMAKFVIFAKMNEAREGRLRCYCMTDDKMDKTLELHENFSEVARSRDIELMEGMPLHLECSGNLVPIRKATQQPRSFSFQAFRDNRLPVSVKVRDSNKEATGFLSFLRKCTKYED----------------------AQHVLCNLNITMP--PCVK-------------VAGSEERR----RTL--TPLALRERYSALNDPAAELARELQFGVDDINRIRVENPNSLLDQSSTLLNLW--ASREGKKAKM-ESLYTALRNIDRADIVAS 1444
BLAST of Ankyrin-2 vs. Ensembl Medaka
Match: ank1a (ankyrin-1 [Source:NCBI gene;Acc:101174837]) HSP 1 Score: 623.239 bits (1606), Expect = 0.000e+0 Identity = 347/802 (43.27%), Postives = 497/802 (61.97%), Query Frame = 2
Query: 137 EKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTN---LGC------------TSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPE 2497
+ ++FLRAARSGN++K E ++ I + +N NGLNA+HLA+KEG+ ++V L+ NG+ ++ T+KGNT+LHIA+LAG+ +VV+ L+ N+N +SQ GFTPLYMAAQENHL+VVK LLE GANQ+I T+DGFTPLAVALQQG++ VV +L+ ++ KVRLPAL D S +GFTPLHIAAHY N+NVA+LL+ + A+ + +TPLH AA+ G ++++L+ A + + T++GLSPIH MA QGD + K L+ ++D +T+D+LT LHVAAHCG+ A+VLL N+RALNGFTPLHIACKK ++++LL+K+ A I + TE+GLTPLH+A+FMG IV ILL+ GAS S + +K E LH+A+R+ E + LL + A +A+A+++QTPLH A RMG+ +V+ LL A+PN T ++ LHIAA+EG + RLLL+ + + TKKGFTPLH+ASKYG+V VA +LLL NPN+ G +GLTPLHVA ++N+ +++ LL+ + + +NGYT LH+ AK+N +EV L+ GA+ NA+S +G TPLHL S G +I+ LL+ A+VN ++GLT LHL A++ I + L+K A + T+MGYT LH A H+G I+ VK LLQ+ +VN++T + C T LH G+I+++ +L L E +H ++ ET+ ++ V E
Sbjct: 6 DAGNSFLRAARSGNLDKALEHIKNGIDINTANQNGLNALHLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPAL-------------------TDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGAN------DELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIH---------------------------------MAAQGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQN-AAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVA-ELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNSKTRVEYIQCHYKDHYCEYKHTTPLHTHLWLGYISVIDVL-------------KLVTEETVSMKHRMSFPETVDEILDVSE 734 HSP 2 Score: 400.593 bits (1028), Expect = 5.582e-114 Identity = 218/604 (36.09%), Postives = 345/604 (57.12%), Query Frame = 1
Query: 2836 DSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPL-PNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQ-LSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLI---FNPDDKKERMCRTIV-KSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALL-LWITTTKDIQKSNLGNQLELSLRDIGREDIV 4626
D+V + P+ GFL+SF+VDA+GG M+ RH +R+ +P + PTRI C L + + + P L + E LA RII L + GP+++EIPH AAL +G+RE+VVL+S+NG+ WKEH N + D ++ L + E +++ E + RI+RII+T P YF+++SR++Q+ IG EGG++ S + VQA FPE A+ K++++ LQ + L+ K GN SP+VT+EPRRRKFH I L +PL P+W D+ R T+SLRLLCS+ G WEDITGT+ L + C SFTT +SAR WL DC RT E V A+ LY E VP++ +F+VF + E ++RC C+TDD +KTLE ENF ++ +EV+E LE SGN++P+ + +Q F++NRL +++D S P G ++F+ S++ + Q +C L+IT+P T +G + + + +N ++ + + ++EL + +A ++G W +L L + ++I +I +++ + ALL LW T++ +++ + L +L+ I R DI+
Sbjct: 806 DNVSPVASPIHTGFLVSFMVDARGGSMRGSRHNGLRVIIPPRTCAAPTRITCRLVKPQKLTSPPPLVEGEGLASRIISLGPAGMQFLGPVIVEIPHFAALGRGDRELVVLRSENGSVWKEHRNRYGDEVLETILNGMDEELESQEELGKKRIRRIISTDFPLYFAVVSRVQQESDLIGPEGGSLTSKLVPMVQATFPETAVTKRVRLGLQAQPVPDELVAKLLGNQANFSPVVTVEPRRRKFHRPIGLRIPLPPSWRDSPRD-SGEGDTTSLRLLCSVIGGTASAQWEDITGTTKLIYANDCASFTTNVSARFWLADCPRTAEAVSFANLLYRELSAVPYMAKFVVFAKMNELREGRLRCYCMTDDKMDKTLEQHENFAEVARSRDIEVMEGMPLHLECSGNLLPVRKATQQPRCFSFQAFRDNRLPVTVKVRDSSKEPTGFLSFLRK------STKYEDS----------QHVLCNLNITMPPCITMRGSEDRRRTLTPLALRERYNALNEPAMASMSAMERTELKMAVIAEQLGLSWAELARELQLSVDDINKIRVENPNSLLEQSSALLNLW--ATREGKRAKM-ESLYTALKSIDRMDII 1389
BLAST of Ankyrin-2 vs. Ensembl Medaka
Match: ENSORLT00000039903.1 (pep primary_assembly:ASM223467v1:15:18469388:18484014:-1 gene:ENSORLG00000030042.1 transcript:ENSORLT00000039903.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 506.138 bits (1302), Expect = 8.996e-164 Identity = 252/440 (57.27%), Postives = 340/440 (77.27%), Query Frame = 2
Query: 95 RIFQMVEETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTM 1414
++F T DS ++LRAAR+GN+EKV ++L++ ++ ++ N NGLNA+HLA+KEG+ EVV L++ G SVD AT+KGNT+LHI+SLAG+ EVV+ L+ + AN+N +SQNGFTPLYMAAQENHL+VV+ LLE A+Q+I T+DGFTPLAVALQQG+D+VV +LL+ND++ KVRLPALHIAA+KDD AA+LL+ +D N D +S SGFTPLHIAAHY N+NVA LL+ + A V+F A+N+ITPLHVAAK G M+KLL+ + A + + T+DGL+P+HC ARSG E ++ ILL+ GA I K+KNGL+ L MATQGD + L+ + VD VT DYLTALHVAAHCG+ A++++ N NA+ALNGFTPLHIACKK + +++ELL+K+ A I + TE+GLTP+H+AAFMG + IV+ L+ +GAS + T +
Sbjct: 6 QLFNESSRTSDSNA----SYLRAARAGNLEKVLDYLKSGVEINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHISSLAGQAEVVTELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLENSASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLL-QNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFMARNDITPLHVAAKRGNSNMVKLLLDRGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKLIVDKKANPNAKALNGFTPLHIACKKNRVRVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVSALINHGASPNTTNV 440 HSP 2 Score: 214.157 bits (544), Expect = 8.943e-60 Identity = 134/398 (33.67%), Postives = 220/398 (55.28%), Query Frame = 2
Query: 1280 IKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
+K IN + GL LH+A+ G E+V LLK GAS+ T K ALH+++ Q E L+ + AN NA+++ TPL++A + + +V LL A ++ T+D +T L +A ++G ++ LLLE+ D K K LHIA++ + A LLL N + G TPLH+A +Y + + LLL+ A V+ + +N TPLH+ AK+ + KLL+DRGA + A+++ G TPLH + +G+++++E+LLD A + + +NGL+ LH+A + + + V+ LL+ + + T TALH A H G + K+++ K + NA+ G T LH+A ++ + ++ LLL + + + GLT + VA + NI L
Sbjct: 37 LKSGVEINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHISSLAGQAEVVTELVTN-GANVNAQSQNGFTPLYMAAQENHLEVVRFLLENSASQSIATEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAA-ALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFMARNDITPLHVAAKRGNSNMVKLLLDRGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKLIVDKKANPNAKALNGFTPLHIACKKNRVRVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVSAL 428 HSP 3 Score: 208.379 bits (529), Expect = 9.415e-58 Identity = 136/422 (32.23%), Postives = 231/422 (54.74%), Query Frame = 2
Query: 1142 AAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQN 2407
AA GN+ LK+ +N NG LH+A K+ ++V L+K A +++ T+ G T LHI++ G E+V L+ NGA+++ + L++AA+ N E + LL A+ + + TPL +A++ G+ +V LL + + K ALHIAA++ + + LLL++ D ++K GFTPLHIA+ YG + VA LLL+ + + + +TPLHVA + M++LLLD A + K+G TPLH A+ +V ++L+DRGA + ++++ G +PLH+ + + ++LLL + V+ + LTALH+AA + + ++ +A+ + K G+T LH A +++ +++LL+ + A T G T +H+AA GH IV L+++ N N
Sbjct: 24 AARAGNLEKVLDYLKSGVEINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHISSLAGQAEVVTELVTNGANVNAQSQNGFTPLYMAAQENHLEVVR-FLLENSASQSIATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVA-TLLLNRAAAVDFMARNDITPLHVAAKRGNSNMVKLLLDRGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKLIVDKKANPNAKALNGFTPLHIACKKNRVRVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVSALINHGASPNTTN 439 HSP 4 Score: 192.2 bits (487), Expect = 3.485e-52 Identity = 129/380 (33.95%), Postives = 202/380 (53.16%), Query Frame = 2
Query: 1340 AAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 2479
AA G+ E V LK+G I+ NALHLA++ E LL A+ +A ++ T LHI+ G +V +L+ GA+ N +++ +T L++AA+E E+ R LLE+ T+ GFTPL +A + G QV LL ++ G L LH+A + + LLL + N + K+G+TPLH+ A I V LL++R A V+ ++ TPLH+ + GN +++LLLD A + + ++GLT LH A +VE LL A I +KT+ G + LH A + V++LLQ + V+ TN T+LH+AA GH + +L++D + + N + G T L +A K++ + + E L K
Sbjct: 24 AARAGNLEKVLDYLKSGVEINICNQNGLNALHLASKEGHVEVVA-ELLKLGASVDAATKKGNTALHISSLAGQAEVVTELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLENSASQSIATEDGFTPLAVALQQGHDQVVSLLL-----ENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFMARNDITPLHVAAKRGNSNMVKLLLDRGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKLIVDKKANPNAKALNGFTPLHIACKKNRVRVMELLLK 397 HSP 5 Score: 173.326 bits (438), Expect = 1.015e-45 Identity = 113/355 (31.83%), Postives = 184/355 (51.83%), Query Frame = 2
Query: 1496 NFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTP-----------------------------LHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
N ++R ++ A R GN V L +G + N+ ++ ALH+A+KEG E+ LL+ DA TKKG T LHI+S G+ +V +L+ + N N+ +G TPL++A NH E++ LL+ A+ + ++G+TP LH+ A+K+ + LL+ N + +S+ GFTPLH+ + GN + LLL+ A V+ A N +T LH+AA++ +++V+ LL A I KT+ G T LH G Q V++LL + + ++T G + LH+A Q H+ V+LLL +++ V+ LTAL VA + +A+ +
Sbjct: 9 NESSRTSDSNASYLRAARAGNLEKVLDYLKSGVEINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHISSLAGQAEVVTELVTNG-ANVNAQSQNGFTPLYMAAQENHLEVVRFLLENSASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFMARNDITPLHVAAKRGNSNMVKLLLDRGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKLI 362
BLAST of Ankyrin-2 vs. Planmine SMEST
Match: SMESG000026655.1 (SMESG000026655.1) HSP 1 Score: 1711.43 bits (4431), Expect = 0.000e+0 Identity = 865/867 (99.77%), Postives = 867/867 (100.00%), Query Frame = 2
Query: 107 MVEETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMXXXXXXXXXXXXXXXXXXXXXXXXIKDISRNNSLRKPNRPVSIGAFN 2707
MVEETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVC+TLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLL+KNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMSDSEEEGSSLNLNSGSSRSSLNLSIKDISRNNSLRKPNRPVSIGAFN
Sbjct: 1 MVEETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMSDSEEEGSSLNLNSGSSRSSLNLSIKDISRNNSLRKPNRPVSIGAFN 867 HSP 2 Score: 1521.14 bits (3937), Expect = 0.000e+0 Identity = 788/791 (99.62%), Postives = 789/791 (99.75%), Query Frame = 1
Query: 2752 FQGDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPXXXXXXXXXHELTNSIESDAMEEEIAESKIKHEEFKSITXXXXXXXXXXXXXXXXXXXXXXXXXXEAELEKMNPNQDCYLGDXXXXXXXXXXXXXXXXAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI 5124
F GDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSI SELNGTVGSPLTQLLPQKP+CTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPSQKSSSLSSHELTNSIESDAMEEEIAESKIKHEEFKSITEEEERQLKQEKLLDLIDYLDSILPDPEAELEKMNPNQDCYLGDEIQEESIQIENISENQAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI
Sbjct: 866 FNGDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSICSELNGTVGSPLTQLLPQKPLCTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPSQKSSSLSSHELTNSIESDAMEEEIAESKIKHEEFKSITEEEERQLKQEKLLDLIDYLDSILPDPEAELEKMNPNQDCYLGDEIQEESIQIENISENQAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI 1656
BLAST of Ankyrin-2 vs. Planmine SMEST
Match: SMESG000026655.1 (SMESG000026655.1) HSP 1 Score: 1694.09 bits (4386), Expect = 0.000e+0 Identity = 856/858 (99.77%), Postives = 858/858 (100.00%), Query Frame = 2
Query: 134 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMXXXXXXXXXXXXXXXXXXXXXXXXIKDISRNNSLRKPNRPVSIGAFN 2707
TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVC+TLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLL+KNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMSDSEEEGSSLNLNSGSSRSSLNLSIKDISRNNSLRKPNRPVSIGAFN
Sbjct: 70 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMSDSEEEGSSLNLNSGSSRSSLNLSIKDISRNNSLRKPNRPVSIGAFN 927 HSP 2 Score: 1521.14 bits (3937), Expect = 0.000e+0 Identity = 788/791 (99.62%), Postives = 789/791 (99.75%), Query Frame = 1
Query: 2752 FQGDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPXXXXXXXXXHELTNSIESDAMEEEIAESKIKHEEFKSITXXXXXXXXXXXXXXXXXXXXXXXXXXEAELEKMNPNQDCYLGDXXXXXXXXXXXXXXXXAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI 5124
F GDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSI SELNGTVGSPLTQLLPQKP+CTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPSQKSSSLSSHELTNSIESDAMEEEIAESKIKHEEFKSITEEEERQLKQEKLLDLIDYLDSILPDPEAELEKMNPNQDCYLGDEIQEESIQIENISENQAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI
Sbjct: 926 FNGDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSICSELNGTVGSPLTQLLPQKPLCTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPSQKSSSLSSHELTNSIESDAMEEEIAESKIKHEEFKSITEEEERQLKQEKLLDLIDYLDSILPDPEAELEKMNPNQDCYLGDEIQEESIQIENISENQAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI 1716 HSP 3 Score: 225.328 bits (573), Expect = 7.165e-59 Identity = 165/552 (29.89%), Postives = 271/552 (49.09%), Query Frame = 2
Query: 1004 QHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTT--------------------MKCEN---------ALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYG------------------------RVQVAR--------QLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVE-QLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q KS A A + E K + I D + L A+H+AA GN ++L++N +V+ G T LHIA + ++V LL++ KA+IN ++ G TPL++AA ++V +LL+ GA+ + TT + +N ALH+AA+ + +L+ + N + ++ TPLHIA N ++ + L+ AD N K+N T LH+AAK G+ E+ +LL+ + ++ T+ G +P+H A++ G +Q+A Q L++ ++ +++ LT LHVA + + E+LL NVN NG+TPLH+ KK ++ +LLI A++N+ ++ G TPLH+ + G+KEI+ +LL A ++ ALHLAA N+ + + LL EA+ + + + T LH AV G V+ LL D N T T+LH+AA++G I RLLL+++ + + K+G T L +A K + +A L
Sbjct: 66 QKKSTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQL 617
BLAST of Ankyrin-2 vs. Planmine SMEST
Match: SMESG000026655.1 (SMESG000026655.1) HSP 1 Score: 1693.32 bits (4384), Expect = 0.000e+0 Identity = 856/858 (99.77%), Postives = 858/858 (100.00%), Query Frame = 2
Query: 134 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMXXXXXXXXXXXXXXXXXXXXXXXXIKDISRNNSLRKPNRPVSIGAFN 2707
TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVC+TLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLL+KNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMSDSEEEGSSLNLNSGSSRSSLNLSIKDISRNNSLRKPNRPVSIGAFN
Sbjct: 90 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTTVPEMMSGSEEKKLILDQPEKMIDHSMSDSEEEGSSLNLNSGSSRSSLNLSIKDISRNNSLRKPNRPVSIGAFN 947 HSP 2 Score: 1522.29 bits (3940), Expect = 0.000e+0 Identity = 788/791 (99.62%), Postives = 789/791 (99.75%), Query Frame = 1
Query: 2752 FQGDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPXXXXXXXXXHELTNSIESDAMEEEIAESKIKHEEFKSITXXXXXXXXXXXXXXXXXXXXXXXXXXEAELEKMNPNQDCYLGDXXXXXXXXXXXXXXXXAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI 5124
F GDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSI SELNGTVGSPLTQLLPQKP+CTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPSQKSSSLSSHELTNSIESDAMEEEIAESKIKHEEFKSITEEEERQLKQEKLLDLIDYLDSILPDPEAELEKMNPNQDCYLGDEIQEESIQIENISENQAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI
Sbjct: 946 FNGDLGYRHSANLYAITPTPNNDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSICSELNGTVGSPLTQLLPQKPLCTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCRTIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIVDESERKFAETIINGGDPSQKSSSLSSHELTNSIESDAMEEEIAESKIKHEEFKSITEEEERQLKQEKLLDLIDYLDSILPDPEAELEKMNPNQDCYLGDEIQEESIQIENISENQAGKTAKSKYHSTVPGNFDLEELEEEIKPQKKMGLRSESYQI 1736 HSP 3 Score: 224.942 bits (572), Expect = 8.420e-59 Identity = 165/552 (29.89%), Postives = 271/552 (49.09%), Query Frame = 2
Query: 1004 QHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTT--------------------MKCEN---------ALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYG------------------------RVQVAR--------QLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVE-QLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETL 2473
Q KS A A + E K + I D + L A+H+AA GN ++L++N +V+ G T LHIA + ++V LL++ KA+IN ++ G TPL++AA ++V +LL+ GA+ + TT + +N ALH+AA+ + +L+ + N + ++ TPLHIA N ++ + L+ AD N K+N T LH+AAK G+ E+ +LL+ + ++ T+ G +P+H A++ G +Q+A Q L++ ++ +++ LT LHVA + + E+LL NVN NG+TPLH+ KK ++ +LLI A++N+ ++ G TPLH+ + G+KEI+ +LL A ++ ALHLAA N+ + + LL EA+ + + + T LH AV G V+ LL D N T T+LH+AA++G I RLLL+++ + + K+G T L +A K + +A L
Sbjct: 86 QKKSTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQL 637
BLAST of Ankyrin-2 vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1) HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0 Identity = 453/787 (57.56%), Postives = 589/787 (74.84%), Query Frame = 2
Query: 134 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKML--LQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTT 2488
+E H+FLRAAR+GN+ KV +FL+ + N GL+A+HLAAKEG+ +V+ LI+ +D T+KGN++LHIASLAGK EVV +L+E+ AN+N++S NGFTPLYMAAQENHL+VV L+ GA+Q ITT+DGFTPLAVALQQG++++V +LL+ND+RSK RLPALHIA KK+DVNA +LL+ SS+ +V+HQS+SGFTPLHIAAHY N A+LLIE+ ADVNF AKNNITPLHVAAKWG+ M++LLI A V+ TRDGL+P+HC+ARSG + L++NGAD+ K++NGLT+L MA QGD + + L+ K +++ T D+LT LHV AH GN A VLL C+ NARALNGFTPLHIACKK + K+VELL+KY A I +TTETGLTPLH++AF+GSKE VN+LL+ GA+I Q TM+ E ALHLA RNNQ ET K LLL A +A+ARENQTPLH+A ++GN ++ L +G+DPN+ T+DNYTALH+AAKEGR E LLL+ K +A+TK+GFTPLHIA+KY +V VA +LL K NPN+ G +GLTPLHVAT+YNH ++ +LLLD +A+ C KNGYTPLH+ AKKN ++ +L+ A+ NA+S+ GF+PL L S G+ +++ LLL ADVNH+A+NGLT++HL A++++ + L+ ADI+ T YT LHTA HFGQI K L L +N +T LG T LHLAAQQGH+ +V LLL++ D N +N QG TA +A+KQHYLNI E L KVTT
Sbjct: 9 SESNHSFLRAARAGNLSKVIDFLETGTDINTCNDIGLSALHLAAKEGHIVIVKELIKREPRIDATTKKGNSALHIASLAGKFEVVKILVENGANVNLQSTNGFTPLYMAAQENHLEVVTFLINNGADQTITTEDGFTPLAVALQQGHERIVALLLENDNRSKQRLPALHIAVKKNDVNAVNLLLNSSEVDVNHQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDSGALVSCRTRDGLTPLHCSARSGHAQLCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLLDRRCDPNARALNGFTPLHIACKKHKIKIVELLLKYGALIEATTETGLTPLHVSAFIGSKEAVNMLLQKGANIEQGTMRGETALHLATRNNQTETVK-LLLKAGAIPDAKARENQTPLHVATKIGNLELITLFLQSGSDPNVATRDNYTALHVAAKEGRSEAISLLLDSGAKIEAETKRGFTPLHIAAKYDKVGVA-SILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLDNKADPKCKAKNGYTPLHIAAKKNNQDLAIMLLVSDADSNAESRNGFSPLQLASQEGHTDVVSLLLQHKADVNHKAKNGLTSMHLTAQEDKVTVARILVHAGADITPTTTAEYTPLHTAAHFGQINMAKYLISLMDQNQINQKTQLGFTPLHLAAQQGHLQLVNLLLESRADPNIKNNQGWTAAHIARKQHYLNIFEVLRKVTT 793 HSP 2 Score: 577.015 bits (1486), Expect = 1.401e-171 Identity = 285/624 (45.67%), Postives = 413/624 (66.19%), Query Frame = 1
Query: 2815 NDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCR-TIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIV-DESERKFA 4680
+DW+ E ++V ++++PV +GFL+SF+VDA+GG MQA R ++R YVP +S GPTR++C L + + P L D + ACRI+ + + PIL+E+PH A+LR ERE+++L+S+NG +WKEH TD A+Q+++G E + T E NRIQRI+T+ LPQYF+LISR++Q++A IG EG ++SSV QVQAVFPEGAL KK ++ +Q H I ++ + GN VA SPI+++EPRRRKFH+ ITLT+PLP + TSSLRLLCSI+G + P VWEDI+G++PL+ CVSFTTT+SAR+WLIDC + ++A+ +Y ES +VP++GQF+V+ RR + EE Q R L +TDD+ +KTLE QENF+LI+SGPLVEVL N +W+E++GN++P+T + +QLS+ I ENR+SF R+KD+ P GK+A + R + + G+ L QKPI TL+I LP++ ++ + + + + K +C I KSEL++R VA ++GGDW+KL LG+ E + ++E AY L+LW + D+ GN+LE +LRDIGRED+VK C+ +IS V DE E+ A
Sbjct: 1064 SDWDFEPENVPIVRKPVSSGFLVSFMVDARGGCMQAQRFTNLRFYVPPSSALGPTRLVCRLIKPSKMNSPPALNDGDGFACRIMEMGPCNTQFNSPILIEVPHYASLRDREREIIILRSENGETWKEHPIEATDQAIQNSVGLSFERLMTNEEVRANRIQRILTSDLPQYFALISRIRQEVALIGPEGVVMSSSVVPQVQAVFPEGALMKKTRVGIQAHEIPVEIVTRLLGNRVACSPIISIEPRRRKFHKPITLTVPLPKTVNKGMINDPNSGTSSLRLLCSITGGSAPAVWEDISGSTPLSFHKDCVSFTTTVSARLWLIDCPNVQGVAEMATNVYRESTVVPYMGQFVVYGRRHDREEAQFRILGLTDDSVDKTLECQENFQLIASGPLVEVLHNRPHWIETAGNLVPVTKTGDQLSMTIEALNENRISFLVRVKDIQQEPKGKLAILLHQRNQGMGA------GNALGTSAVQKPITTLEICLPSE-----IHPVSDTLRRKKMKTGEFIKTTICTDKIAKSELDLRAVADQIGGDWEKLAAALGISDSEDLHNIRNNSSDEYSAYALLILWRSKRGDLV---CGNELEKALRDIGREDVVKNCMINISFVTDEDEKSQA 1673
BLAST of Ankyrin-2 vs. Planmine SMEST
Match: SMESG000000606.1 (SMESG000000606.1) HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0 Identity = 453/787 (57.56%), Postives = 589/787 (74.84%), Query Frame = 2
Query: 134 TEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCKTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKML--LQKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKVTT 2488
+E H+FLRAAR+GN+ KV +FL+ + N GL+A+HLAAKEG+ +V+ LI+ +D T+KGN++LHIASLAGK EVV +L+E+ AN+N++S NGFTPLYMAAQENHL+VV L+ GA+Q ITT+DGFTPLAVALQQG++++V +LL+ND+RSK RLPALHIA KK+DVNA +LL+ SS+ +V+HQS+SGFTPLHIAAHY N A+LLIE+ ADVNF AKNNITPLHVAAKWG+ M++LLI A V+ TRDGL+P+HC+ARSG + L++NGAD+ K++NGLT+L MA QGD + + L+ K +++ T D+LT LHV AH GN A VLL C+ NARALNGFTPLHIACKK + K+VELL+KY A I +TTETGLTPLH++AF+GSKE VN+LL+ GA+I Q TM+ E ALHLA RNNQ ET K LLL A +A+ARENQTPLH+A ++GN ++ L +G+DPN+ T+DNYTALH+AAKEGR E LLL+ K +A+TK+GFTPLHIA+KY +V VA +LL K NPN+ G +GLTPLHVAT+YNH ++ +LLLD +A+ C KNGYTPLH+ AKKN ++ +L+ A+ NA+S+ GF+PL L S G+ +++ LLL ADVNH+A+NGLT++HL A++++ + L+ ADI+ T YT LHTA HFGQI K L L +N +T LG T LHLAAQQGH+ +V LLL++ D N +N QG TA +A+KQHYLNI E L KVTT
Sbjct: 9 SESNHSFLRAARAGNLSKVIDFLETGTDINTCNDIGLSALHLAAKEGHIVIVKELIKREPRIDATTKKGNSALHIASLAGKFEVVKILVENGANVNLQSTNGFTPLYMAAQENHLEVVTFLINNGADQTITTEDGFTPLAVALQQGHERIVALLLENDNRSKQRLPALHIAVKKNDVNAVNLLLNSSEVDVNHQSSSGFTPLHIAAHYGNEKSAQLLIEQKADVNFQAKNNITPLHVAAKWGRSGMVQLLIDSGALVSCRTRDGLTPLHCSARSGHAQLCEKLIDNGADVMSKTRNGLTSLHMAAQGDFEDTARILLLKRANINETTTDFLTPLHVTAHYGNEKVARVLLDRRCDPNARALNGFTPLHIACKKHKIKIVELLLKYGALIEATTETGLTPLHVSAFIGSKEAVNMLLQKGANIEQGTMRGETALHLATRNNQTETVK-LLLKAGAIPDAKARENQTPLHVATKIGNLELITLFLQSGSDPNVATRDNYTALHVAAKEGRSEAISLLLDSGAKIEAETKRGFTPLHIAAKYDKVGVA-SILLQKKANPNATGKNGLTPLHVATHYNHEKVAQLLLDNKADPKCKAKNGYTPLHIAAKKNNQDLAIMLLVSDADSNAESRNGFSPLQLASQEGHTDVVSLLLQHKADVNHKAKNGLTSMHLTAQEDKVTVARILVHAGADITPTTTAEYTPLHTAAHFGQINMAKYLISLMDQNQINQKTQLGFTPLHLAAQQGHLQLVNLLLESRADPNIKNNQGWTAAHIARKQHYLNIFEVLRKVTT 793 HSP 2 Score: 577.015 bits (1486), Expect = 1.278e-171 Identity = 285/624 (45.67%), Postives = 413/624 (66.19%), Query Frame = 1
Query: 2815 NDWEMELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPTRIICHLQRKELYPTLPLLEDSEALACRIIHLNASTQSLDGPILLEIPHSAALRQGEREVVVLKSDNGASWKEHTNLFTDIAVQDALGNLAENIQTTEYQTRNRIQRIITTSLPQYFSLISRLKQDMAFIGAEGGTVNSSVCTQVQAVFPEGALKKKIKISLQIHNIQRNLIQKYFGNGVAISPIVTLEPRRRKFHEAITLTLPLPNWSDANRSIPYTVQTSSLRLLCSISGQNTPTVWEDITGTSPLTIKDGCVSFTTTISARVWLIDCNRTNEIVQIASTLYEESCIVPFIGQFLVFCRRKNEEECQIRCLCITDDTAEKTLEFQENFELISSGPLVEVLENHTYWLESSGNIIPITNSDEQLSLKITPFQENRLSFYARIKDLSNPPCGKVAFMEDPRIPSISSELNGTVGSPLTQLLPQKPICTLDITLPTKPTQKGLNNIDEEFSNDLIFNPDDKKERMCR-TIVKSELNIREVALKVGGDWKKLTINLGMGQEEITRIDLQSGTEEDKAYVALLLWITTTKDIQKSNLGNQLELSLRDIGREDIVKTCIHDISIV-DESERKFA 4680
+DW+ E ++V ++++PV +GFL+SF+VDA+GG MQA R ++R YVP +S GPTR++C L + + P L D + ACRI+ + + PIL+E+PH A+LR ERE+++L+S+NG +WKEH TD A+Q+++G E + T E NRIQRI+T+ LPQYF+LISR++Q++A IG EG ++SSV QVQAVFPEGAL KK ++ +Q H I ++ + GN VA SPI+++EPRRRKFH+ ITLT+PLP + TSSLRLLCSI+G + P VWEDI+G++PL+ CVSFTTT+SAR+WLIDC + ++A+ +Y ES +VP++GQF+V+ RR + EE Q R L +TDD+ +KTLE QENF+LI+SGPLVEVL N +W+E++GN++P+T + +QLS+ I ENR+SF R+KD+ P GK+A + R + + G+ L QKPI TL+I LP++ ++ + + + + K +C I KSEL++R VA ++GGDW+KL LG+ E + ++E AY L+LW + D+ GN+LE +LRDIGRED+VK C+ +IS V DE E+ A
Sbjct: 1064 SDWDFEPENVPIVRKPVSSGFLVSFMVDARGGCMQAQRFTNLRFYVPPSSALGPTRLVCRLIKPSKMNSPPALNDGDGFACRIMEMGPCNTQFNSPILIEVPHYASLRDREREIIILRSENGETWKEHPIEATDQAIQNSVGLSFERLMTNEEVRANRIQRILTSDLPQYFALISRIRQEVALIGPEGVVMSSSVVPQVQAVFPEGALMKKTRVGIQAHEIPVEIVTRLLGNRVACSPIISIEPRRRKFHKPITLTVPLPKTVNKGMINDPNSGTSSLRLLCSITGGSAPAVWEDISGSTPLSFHKDCVSFTTTVSARLWLIDCPNVQGVAEMATNVYRESTVVPYMGQFVVYGRRHDREEAQFRILGLTDDSVDKTLECQENFQLIASGPLVEVLHNRPHWIETAGNLVPVTKTGDQLSMTIEALNENRISFLVRVKDIQQEPKGKLAILLHQRNQGMGA------GNALGTSAVQKPITTLEICLPSE-----IHPVSDTLRRKKMKTGEFIKTTICTDKIAKSELDLRAVADQIGGDWEKLAAALGISDSEDLHNIRNNSSDEYSAYALLILWRSKRGDLV---CGNELEKALRDIGREDVVKNCMINISFVTDEDEKSQA 1673 The following BLAST results are available for this feature:
BLAST of Ankyrin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ankyrin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Ankyrin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Ankyrin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Ankyrin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012522 ID=SMED30012522|Name=Ankyrin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=5132bpback to top protein sequence of SMED30012522-orf-1 >SMED30012522-orf-1 ID=SMED30012522-orf-1|Name=SMED30012522-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=768bp MELDSVQLIQRPVRAGFLISFIVDAKGGVMQAHRHPDIRIYVPQNSVDGPback to top protein sequence of SMED30012522-orf-2 >SMED30012522-orf-2 ID=SMED30012522-orf-2|Name=SMED30012522-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=872bp MVEETKDSLTEKAHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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