Kunitz-type protease inhibitor

Overview


Name	Kunitz-type protease inhibitor
Smed ID	SMED30012509
Length (bp)	321

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Kunitz-type protease inhibitor (SMED30012509) t-SNE clustered cells

Violin plots show distribution of expression levels for Kunitz-type protease inhibitor (SMED30012509) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kunitz-type protease inhibitor (SMED30012509) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kunitz-type protease inhibitor (SMED30012509) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012509

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30012509		SmedASXL_006185	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30012509		SmedASXL_006185	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
neoblast	SMED30012509		dd_Smed_v4_1446_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30012509	h1SMcG0013308	OX_Smed_1.0.23166	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 66.6254 bits (161), Expect = 6.484e-14
Identity = 29/51 (56.86%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C   +DPG CR    R++Y+   KQCE F YGGC GN NNF+T+EECK+IC
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175

HSP 2 Score: 58.151 bits (139), Expect = 7.446e-11
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C    D G C+A  +RF+++   +QCE F YGGC GN N F+++EECK +C ++
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 107

[Close]

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C   +DPG CR    R++Y+   KQCE F YGGC GN NNF+T+EECK+IC
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175

HSP 2 Score: 58.151 bits (139), Expect = 7.446e-11
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C    D G C+A  +RF+++   +QCE F YGGC GN N F+++EECK +C ++
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 107

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 65.4698 bits (158), Expect = 8.387e-14
Identity = 29/51 (56.86%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C   +DPG CR    R++Y+   KQCE F YGGC GN NNF+T+EECK+IC
Sbjct:  112 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 162

HSP 2 Score: 56.9954 bits (136), Expect = 1.253e-10
Identity = 24/53 (45.28%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C    D G C+A  +RF+++   +QCE F YGGC GN N F+++EECK +C +
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 65.4698 bits (158), Expect = 1.961e-13
Identity = 29/51 (56.86%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C   +DPG CR    R++Y+   KQCE F YGGC GN NNF+T+EECK+IC
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175

HSP 2 Score: 57.7658 bits (138), Expect = 1.455e-10
Identity = 28/53 (52.83%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P D G CRAN  RFYY+ V  +C  F Y GCGGN NNF + +EC   C K
Sbjct:  217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269

HSP 3 Score: 57.3806 bits (137), Expect = 1.705e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C    D G C+A  +RF+++   +QCE F YGGC GN N F+++EECK +C ++
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 107

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 65.4698 bits (158), Expect = 1.961e-13
Identity = 29/51 (56.86%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C   +DPG CR    R++Y+   KQCE F YGGC GN NNF+T+EECK+IC
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175

HSP 2 Score: 57.7658 bits (138), Expect = 1.455e-10
Identity = 28/53 (52.83%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P D G CRAN  RFYY+ V  +C  F Y GCGGN NNF + +EC   C K
Sbjct:  217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269

HSP 3 Score: 57.3806 bits (137), Expect = 1.705e-10
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C    D G C+A  +RF+++   +QCE F YGGC GN N F+++EECK +C ++
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 107

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 63.1586 bits (152), Expect = 9.424e-13
Identity = 27/53 (50.94%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P+D G CR  F R+++D   K C+ F+Y GC GNGNNF + EEC +IC K
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 2 Score: 56.6102 bits (135), Expect = 1.525e-10
Identity = 21/45 (46.67%), Postives = 35/45 (77.78%), Query Frame = 1

Query:  133 PGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            PG C  +F+R++Y++ +++CE F+Y GCGGNGNN+++ E C+  C
Sbjct:  429 PGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 3 Score: 56.6102 bits (135), Expect = 1.681e-10
Identity = 26/57 (45.61%), Postives = 36/57 (63.16%), Query Frame = 1

Query:  100 SSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            S  A C+A  + G C   F RF +D+    C +F+YGGCGGN NNF T++EC + C+
Sbjct:  861 SPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 917

HSP 4 Score: 55.0694 bits (131), Expect = 5.837e-10
Identity = 23/54 (42.59%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P   G C+    R+YYD+V   C  F Y GC GN NNF ++E+C+ +C+ N
Sbjct: 2742 CIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLN 2795

HSP 5 Score: 48.1358 bits (113), Expect = 1.580e-7
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK+ G C     RFY++    +C+ F +GGC GN NNF+ +E+C+S C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 6 Score: 45.8246 bits (107), Expect = 1.083e-6
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P D G C     R++++    QCE F+YG CGGN NNF     C+  CM +
Sbjct: 2177 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCMPH 2230

HSP 7 Score: 45.8246 bits (107), Expect = 1.193e-6
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P +PG C+    R+Y++  +  C  F YGGC GN N+F T +EC+  C +
Sbjct: 1083 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1135

HSP 8 Score: 43.1282 bits (100), Expect = 9.269e-6
Identity = 19/50 (38.00%), Postives = 30/50 (60.00%), Query Frame = 1

Query:  127 KDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            KD G  +    ++Y++  N +CE F + G GGN N F+T+ EC+ IC  +
Sbjct: 2245 KDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTPS 2294

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3g.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 63.1586 bits (152), Expect = 9.464e-13
Identity = 27/53 (50.94%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P+D G CR  F R+++D   K C+ F+Y GC GNGNNF + EEC +IC K
Sbjct:  507 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 559

HSP 2 Score: 56.9954 bits (136), Expect = 1.298e-10
Identity = 26/57 (45.61%), Postives = 36/57 (63.16%), Query Frame = 1

Query:  100 SSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            S  A C+A  + G C   F RF +D+    C +F+YGGCGGN NNF T++EC + C+
Sbjct:  631 SPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 687

HSP 3 Score: 56.6102 bits (135), Expect = 1.624e-10
Identity = 21/45 (46.67%), Postives = 35/45 (77.78%), Query Frame = 1

Query:  133 PGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            PG C  +F+R++Y++ +++CE F+Y GCGGNGNN+++ E C+  C
Sbjct:  208 PGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 4 Score: 55.4546 bits (132), Expect = 4.733e-10
Identity = 23/54 (42.59%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P   G C+    R+YYD+V   C  F Y GC GN NNF ++E+C+ +C+ N
Sbjct: 1986 CIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLN 2039

HSP 5 Score: 48.521 bits (114), Expect = 1.269e-7
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK+ G C     RFY++    +C+ F +GGC GN NNF+ +E+C+S C
Sbjct:  318 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 6 Score: 46.2098 bits (108), Expect = 8.203e-7
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P D G C     R++++    QCE F+YG CGGN NNF     C+  CM +
Sbjct: 1421 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCMPH 1474

HSP 7 Score: 45.8246 bits (107), Expect = 8.952e-7
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P +PG C+    R+Y++  +  C  F YGGC GN N+F T +EC+  C +
Sbjct:  853 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 905

HSP 8 Score: 43.1282 bits (100), Expect = 9.043e-6
Identity = 19/50 (38.00%), Postives = 30/50 (60.00%), Query Frame = 1

Query:  127 KDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            KD G  +    ++Y++  N +CE F + G GGN N F+T+ EC+ IC  +
Sbjct: 1489 KDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTPS 1538

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3f.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 63.1586 bits (152), Expect = 9.465e-13
Identity = 27/53 (50.94%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P+D G CR  F R+++D   K C+ F+Y GC GNGNNF + EEC +IC K
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 568

HSP 2 Score: 56.9954 bits (136), Expect = 1.311e-10
Identity = 26/57 (45.61%), Postives = 36/57 (63.16%), Query Frame = 1

Query:  100 SSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            S  A C+A  + G C   F RF +D+    C +F+YGGCGGN NNF T++EC + C+
Sbjct:  640 SPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 696

HSP 3 Score: 56.6102 bits (135), Expect = 1.640e-10
Identity = 21/45 (46.67%), Postives = 35/45 (77.78%), Query Frame = 1

Query:  133 PGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            PG C  +F+R++Y++ +++CE F+Y GCGGNGNN+++ E C+  C
Sbjct:  208 PGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 4 Score: 55.4546 bits (132), Expect = 4.733e-10
Identity = 23/54 (42.59%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P   G C+    R+YYD+V   C  F Y GC GN NNF ++E+C+ +C+ N
Sbjct: 1995 CIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLN 2048

HSP 5 Score: 48.521 bits (114), Expect = 1.269e-7
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK+ G C     RFY++    +C+ F +GGC GN NNF+ +E+C+S C
Sbjct:  318 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 6 Score: 46.2098 bits (108), Expect = 8.283e-7
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P D G C     R++++    QCE F+YG CGGN NNF     C+  CM +
Sbjct: 1430 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCMPH 1483

HSP 7 Score: 45.8246 bits (107), Expect = 9.491e-7
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P +PG C+    R+Y++  +  C  F YGGC GN N+F T +EC+  C +
Sbjct:  862 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 914

HSP 8 Score: 43.1282 bits (100), Expect = 9.132e-6
Identity = 19/50 (38.00%), Postives = 30/50 (60.00%), Query Frame = 1

Query:  127 KDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            KD G  +    ++Y++  N +CE F + G GGN N F+T+ EC+ IC  +
Sbjct: 1498 KDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTPS 1547

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 63.1586 bits (152), Expect = 9.609e-13
Identity = 27/53 (50.94%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P+D G CR  F R+++D   K C+ F+Y GC GNGNNF + EEC +IC K
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 780

HSP 2 Score: 56.6102 bits (135), Expect = 1.525e-10
Identity = 21/45 (46.67%), Postives = 35/45 (77.78%), Query Frame = 1

Query:  133 PGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            PG C  +F+R++Y++ +++CE F+Y GCGGNGNN+++ E C+  C
Sbjct:  429 PGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 3 Score: 56.6102 bits (135), Expect = 1.731e-10
Identity = 26/57 (45.61%), Postives = 36/57 (63.16%), Query Frame = 1

Query:  100 SSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            S  A C+A  + G C   F RF +D+    C +F+YGGCGGN NNF T++EC + C+
Sbjct:  852 SPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 908

HSP 4 Score: 55.0694 bits (131), Expect = 5.837e-10
Identity = 23/54 (42.59%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P   G C+    R+YYD+V   C  F Y GC GN NNF ++E+C+ +C+ N
Sbjct: 2733 CIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLN 2786

HSP 5 Score: 48.1358 bits (113), Expect = 1.565e-7
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK+ G C     RFY++    +C+ F +GGC GN NNF+ +E+C+S C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 6 Score: 45.8246 bits (107), Expect = 1.072e-6
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P D G C     R++++    QCE F+YG CGGN NNF     C+  CM +
Sbjct: 2168 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCMPH 2221

HSP 7 Score: 45.8246 bits (107), Expect = 1.170e-6
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P +PG C+    R+Y++  +  C  F YGGC GN N+F T +EC+  C +
Sbjct: 1074 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1126

HSP 8 Score: 43.1282 bits (100), Expect = 9.269e-6
Identity = 19/50 (38.00%), Postives = 30/50 (60.00%), Query Frame = 1

Query:  127 KDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            KD G  +    ++Y++  N +CE F + G GGN N F+T+ EC+ IC  +
Sbjct: 2236 KDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTPS 2285

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 63.1586 bits (152), Expect = 9.670e-13
Identity = 27/53 (50.94%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P+D G CR  F R+++D   K C+ F+Y GC GNGNNF + EEC +IC K
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 2 Score: 56.9954 bits (136), Expect = 1.420e-10
Identity = 26/57 (45.61%), Postives = 36/57 (63.16%), Query Frame = 1

Query:  100 SSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            S  A C+A  + G C   F RF +D+    C +F+YGGCGGN NNF T++EC + C+
Sbjct:  861 SPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 917

HSP 3 Score: 56.6102 bits (135), Expect = 1.675e-10
Identity = 21/45 (46.67%), Postives = 35/45 (77.78%), Query Frame = 1

Query:  133 PGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            PG C  +F+R++Y++ +++CE F+Y GCGGNGNN+++ E C+  C
Sbjct:  429 PGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 4 Score: 55.4546 bits (132), Expect = 4.883e-10
Identity = 23/54 (42.59%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P   G C+    R+YYD+V   C  F Y GC GN NNF ++E+C+ +C+ N
Sbjct: 2216 CIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLN 2269

HSP 5 Score: 48.1358 bits (113), Expect = 1.388e-7
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK+ G C     RFY++    +C+ F +GGC GN NNF+ +E+C+S C
Sbjct:  539 CSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 6 Score: 45.8246 bits (107), Expect = 9.417e-7
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P D G C     R++++    QCE F+YG CGGN NNF     C+  CM +
Sbjct: 1651 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCMPH 1704

HSP 7 Score: 45.8246 bits (107), Expect = 9.982e-7
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P +PG C+    R+Y++  +  C  F YGGC GN N+F T +EC+  C +
Sbjct: 1083 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCAR 1135

HSP 8 Score: 43.1282 bits (100), Expect = 9.985e-6
Identity = 19/50 (38.00%), Postives = 30/50 (60.00%), Query Frame = 1

Query:  127 KDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            KD G  +    ++Y++  N +CE F + G GGN N F+T+ EC+ IC  +
Sbjct: 1719 KDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERICTPS 1768

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 62.003 bits (149), Expect = 1.962e-13
Identity = 26/53 (49.06%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            DC  PK+ GRC A F R+ Y+   + CE F YGGC GN NNF++ E+C+  C+
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQACL 106

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 62.003 bits (149), Expect = 1.962e-13
Identity = 26/53 (49.06%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            DC  PK+ GRC A F R+ Y+   + CE F YGGC GN NNF++ E+C+  C+
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQACL 106

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG17380 (gene:FBgn0039077 transcript:FBtr0299867)

HSP 1 Score: 56.225 bits (134), Expect = 3.148e-11
Identity = 26/51 (50.98%), Postives = 30/51 (58.82%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C    +PG C+ NF  F YD  N  C  F YGGCGGN N FQT +EC  +C
Sbjct:   25 CSFIANPGPCKGNFEMFAYDMDNNVCVEFIYGGCGGNPNRFQTKKECILLC 75

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0077556)

HSP 1 Score: 53.9138 bits (128), Expect = 1.290e-10
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  PK PG CR +  R+ Y++    CE+F Y GC    NNF T EEC+  CM+
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQ 93

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0446100)

HSP 1 Score: 53.9138 bits (128), Expect = 1.290e-10
Identity = 24/53 (45.28%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  PK PG CR +  R+ Y++    CE+F Y GC    NNF T EEC+  CM+
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQ 93

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: spint1b (serine peptidase inhibitor, Kunitz type 1 b [Source:ZFIN;Acc:ZDB-GENE-071218-1])

HSP 1 Score: 62.3882 bits (150), Expect = 2.772e-12
Identity = 26/53 (49.06%), Postives = 36/53 (67.92%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            A C  P   G CRA+F  +YYD ++K+C +F+YGGC GN NNF+T ++C   C
Sbjct:  361 AHCTDPPATGPCRAHFHHWYYDPLSKKCHSFTYGGCDGNRNNFETADKCMKNC 413

HSP 2 Score: 50.447 bits (119), Expect = 4.091e-8
Identity = 22/51 (43.14%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK  G CRA+F R+ Y+  +++CE F +GGC  N NN+ +  EC++ C
Sbjct:  235 CLTPKKTGPCRASFIRWNYNAASRRCEQFIFGGCMENSNNYLSETECQNAC 285

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: appa (amyloid beta (A4) precursor protein a [Source:ZFIN;Acc:ZDB-GENE-000616-13])

HSP 1 Score: 61.6178 bits (148), Expect = 4.289e-12
Identity = 25/51 (49.02%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C A  + G CRA   R+YY +  ++C  F YGGCGGN NNF++ E C S+C
Sbjct:  293 CFASAETGPCRAMLSRWYYVREERRCAPFIYGGCGGNRNNFESEEYCLSVC 343

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: wfikkn2a (info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a [Source:ZFIN;Acc:ZDB-GENE-120914-1])

HSP 1 Score: 61.2326 bits (147), Expect = 6.366e-12
Identity = 27/60 (45.00%), Postives = 37/60 (61.67%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            SCG+   A C  P   G C+A   R+ Y    K+C++F YGGCGGN NNF++ E C+ +C
Sbjct:  374 SCGAELAAPCSLPSVQGPCKAYKPRWAYSHALKKCQSFVYGGCGGNENNFESKEACEEMC 433

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 58.9214 bits (141), Expect = 3.141e-11
Identity = 25/52 (48.08%), Postives = 35/52 (67.31%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C   KD G C+A   RFY+D    +CE F YGGC GN NNF+T+++C+ +C+
Sbjct:   42 CALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMCL 93

HSP 2 Score: 55.4546 bits (132), Expect = 5.638e-10
Identity = 23/57 (40.35%), Postives = 37/57 (64.91%), Query Frame = 1

Query:   97 SSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            + + + C    +PG CR    R+++DQ +++C+ F YGGC GN NNF+TI+ C+  C
Sbjct:   95 TENKSPCHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRC 151

HSP 3 Score: 44.669 bits (104), Expect = 3.500e-6
Identity = 22/57 (38.60%), Postives = 31/57 (54.39%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN*SR 285
            C +  D G C  + RR+ ++    +C+ F Y GCGGN NNF     C  +CMK+  R
Sbjct:  205 CMSAVDRGDCDGSERRYVFNPRIGRCQVFRYSGCGGNKNNFIHKRHCMKMCMKDQHR 261

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 58.9214 bits (141), Expect = 3.352e-11
Identity = 25/52 (48.08%), Postives = 35/52 (67.31%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C   KD G C+A   RFY+D    +CE F YGGC GN NNF+T+++C+ +C+
Sbjct:   41 CALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMCL 92

HSP 2 Score: 55.4546 bits (132), Expect = 5.450e-10
Identity = 23/57 (40.35%), Postives = 37/57 (64.91%), Query Frame = 1

Query:   97 SSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            + + + C    +PG CR    R+++DQ +++C+ F YGGC GN NNF+TI+ C+  C
Sbjct:   94 TENKSPCHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRC 150

HSP 3 Score: 44.669 bits (104), Expect = 3.564e-6
Identity = 22/57 (38.60%), Postives = 31/57 (54.39%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN*SR 285
            C +  D G C  + RR+ ++    +C+ F Y GCGGN NNF     C  +CMK+  R
Sbjct:  204 CMSAVDRGDCDGSERRYVFNPRIGRCQVFRYSGCGGNKNNFIHKRHCMKMCMKDQHR 260

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 62.3882 bits (150), Expect = 3.644e-12
Identity = 25/52 (48.08%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C+  K+ G CR    ++YYD   K C  F YGGCGGN N F T +EC+ IC+
Sbjct: 3026 CNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKICI 3077

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 62.3882 bits (150), Expect = 3.896e-12
Identity = 25/52 (48.08%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C+  K+ G CR    ++YYD   K C  F YGGCGGN N F T +EC+ IC+
Sbjct: 2829 CNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKICI 2880

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 62.3882 bits (150), Expect = 3.900e-12
Identity = 25/52 (48.08%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C+  K+ G CR    ++YYD   K C  F YGGCGGN N F T +EC+ IC+
Sbjct: 3009 CNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKICI 3060

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:548483])

HSP 1 Score: 60.077 bits (144), Expect = 1.071e-11
Identity = 27/53 (50.94%), Postives = 36/53 (67.92%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C +PKD G C A+  R+Y++  +K CE F Y GCGGN NNF  +E+C S+C K
Sbjct:  149 CYSPKDEGSCSASVTRYYFNIESKACEEFVYTGCGGNSNNFVKMEDCDSVCKK 201

HSP 2 Score: 56.225 bits (134), Expect = 2.331e-10
Identity = 23/53 (43.40%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P D G C+A    +YYD+  + C+ F YGGC GN N F ++E+C+  C K
Sbjct:   29 CLLPPDEGPCKALIPHYYYDRYTQTCQEFLYGGCDGNSNKFLSMEDCEKFCWK 81

HSP 3 Score: 45.0542 bits (105), Expect = 3.433e-6
Identity = 21/51 (41.18%), Postives = 26/51 (50.98%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C    D G CR   +R+ Y+    +CE F YGGC GN NNF+    C   C
Sbjct:   89 CRMDPDEGPCRGFLKRYAYNMQTMKCEQFYYGGCYGNDNNFKDKASCMDFC 139

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:NCBI gene;Acc:733874])

HSP 1 Score: 60.4622 bits (145), Expect = 1.644e-11
Identity = 26/51 (50.98%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C AP   G CRA+FRR+YYD     C  F+YGGC GN NN+ ++E+C   C
Sbjct:  268 CAAPSLTGPCRASFRRWYYDVTTATCVAFTYGGCRGNKNNYLSVEDCVKNC 318

HSP 2 Score: 53.5286 bits (127), Expect = 3.963e-9
Identity = 21/45 (46.67%), Postives = 33/45 (73.33%), Query Frame = 1

Query:  136 GRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            G CRA+F R+Y+D  ++ C +F+YGGCGG  NN ++++EC   C+
Sbjct:  203 GNCRASFPRWYFDAESQNCISFTYGGCGGTENNHKSVQECADRCI 247

HSP 3 Score: 45.8246 bits (107), Expect = 2.165e-6
Identity = 21/44 (47.73%), Postives = 27/44 (61.36%), Query Frame = 1

Query:  136 GRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            G CRA F R++Y+   + CE F+YGGC GN NN    E C + C
Sbjct:  126 GPCRAAFERWWYNPNTQTCENFTYGGCKGNLNNHIGEEVCMNKC 169

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Match: Tfpi2 (tissue factor pathway inhibitor 2 [Source:MGI Symbol;Acc:MGI:108543])

HSP 1 Score: 65.4698 bits (158), Expect = 8.318e-15
Identity = 29/53 (54.72%), Postives = 36/53 (67.92%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C +PKD G C AN  RFY++  NK CETF+Y GCGGN NNF  ++ C   C+K
Sbjct:   38 CSSPKDEGLCSANVTRFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACVK 90

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Match: Tfpi (tissue factor pathway inhibitor [Source:MGI Symbol;Acc:MGI:1095418])

HSP 1 Score: 66.6254 bits (161), Expect = 3.600e-14
Identity = 31/64 (48.44%), Postives = 42/64 (65.62%), Query Frame = 1

Query:   88 SCGSSSGAD----CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +  ++SGA+    C   +DPG CR   +R+ Y+   KQCE F YGGC GN NNF+T++ECK IC
Sbjct:  108 AVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKIC 171

HSP 2 Score: 56.225 bits (134), Expect = 2.162e-10
Identity = 24/52 (46.15%), Postives = 31/52 (59.62%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C    D G C+A  R ++++    QCE F YGGC GN N F T+EECK  C+
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCI 101

[Close]

Query:   88 SCGSSSGAD----CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +  ++SGA+    C   +DPG CR   +R+ Y+   KQCE F YGGC GN NNF+T++ECK IC
Sbjct:  108 AVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKIC 171

HSP 2 Score: 56.225 bits (134), Expect = 2.162e-10
Identity = 24/52 (46.15%), Postives = 31/52 (59.62%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C    D G C+A  R ++++    QCE F YGGC GN N F T+EECK  C+
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCI 101

[Close]

Query:   88 SCGSSSGAD----CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +  ++SGA+    C   +DPG CR   +R+ Y+   KQCE F YGGC GN NNF+T++ECK IC
Sbjct:  108 AVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKIC 171

HSP 2 Score: 56.225 bits (134), Expect = 2.162e-10
Identity = 24/52 (46.15%), Postives = 31/52 (59.62%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C    D G C+A  R ++++    QCE F YGGC GN N F T+EECK  C+
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCI 101

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Match: Tfpi (tissue factor pathway inhibitor [Source:MGI Symbol;Acc:MGI:1095418])

HSP 1 Score: 66.2402 bits (160), Expect = 5.872e-14
Identity = 31/64 (48.44%), Postives = 42/64 (65.62%), Query Frame = 1

Query:   88 SCGSSSGAD----CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +  ++SGA+    C   +DPG CR   +R+ Y+   KQCE F YGGC GN NNF+T++ECK IC
Sbjct:  108 AVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKIC 171

HSP 2 Score: 55.8398 bits (133), Expect = 3.108e-10
Identity = 24/52 (46.15%), Postives = 31/52 (59.62%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C    D G C+A  R ++++    QCE F YGGC GN N F T+EECK  C+
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCI 101

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DN13|VKT9_ANEVI (U-actitoxin-Avd3l OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.222e-18
Identity = 31/52 (59.62%), Postives = 40/52 (76.92%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            DC  P D GRCRA F R+YY+  +++CE F+YGGCGGN NNF T+EEC+ +C
Sbjct:   20 DCLLPMDVGRCRARFPRYYYNSSSRRCEKFNYGGCGGNANNFHTLEECEKVC 71

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|Q9TWF8|VKT3_ANESU (KappaPI-actitoxin-Avd3d OS=Anemonia sulcata OX=6108 PE=1 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 5.135e-18
Identity = 31/53 (58.49%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
             DC+ PK  GRCRA F R+YY+  +++CE F YGGCGGN NNF T+EEC+ +C
Sbjct:    3 GDCELPKVVGRCRARFPRYYYNLSSRRCEKFIYGGCGGNANNFHTLEECEKVC 55

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DN07|VKT4_ANEVI (U-actitoxin-Avd3g OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 7.526e-18
Identity = 31/52 (59.62%), Postives = 40/52 (76.92%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            DC+ PK  GRCRA F R+YY+  +++CE F+YGGCGGN NNF T+EEC  +C
Sbjct:   20 DCELPKVVGRCRARFPRYYYNSSSRRCEKFNYGGCGGNANNFHTLEECVKVC 71

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P10280|VKT52_ANESU (KappaPI-actitoxin-Avd3a OS=Anemonia sulcata OX=6108 PE=1 SV=2)

HSP 1 Score: 72.7886 bits (177), Expect = 2.940e-17
Identity = 31/53 (58.49%), Postives = 39/53 (73.58%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
             DC+ PK  G CRA F R+YY+  +K+CE F YGGCGGN NNF T+EEC+ +C
Sbjct:    3 GDCELPKVVGPCRARFPRYYYNSSSKRCEKFIYGGCGGNANNFHTLEECEKVC 55

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DN08|VKT53_ANEVI (KappaPI-actitoxin-Avd3e OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 3.174e-17
Identity = 31/52 (59.62%), Postives = 39/52 (75.00%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            DC+ PK  G CRA F R+YY+  +K+CE F YGGCGGN NNF T+EEC+ +C
Sbjct:   20 DCELPKVVGPCRARFPRYYYNSSSKRCEKFIYGGCGGNANNFHTLEECEKVC 71

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: A0A0C2CY52 (Kunitz/Bovine pancreatic trypsin inhibitor domain protein OS=Ancylostoma duodenale OX=51022 GN=ANCDUO_07771 PE=4 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 2.571e-15
Identity = 34/63 (53.97%), Postives = 43/63 (68.25%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            S   +  ADC  PK  GRCRA+FRR+YYD   K+C+ F+YGGC GNGN F T E C+  CM++
Sbjct:    3 SQAEARNADCLLPKRVGRCRASFRRYYYDSEEKKCKMFTYGGCRGNGNRFLTEENCRKECMQD 65

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: A0A4S2L009 (BPTI/Kunitz inhibitor domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010267 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 2.319e-14
Identity = 29/56 (51.79%), Postives = 42/56 (75.00%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            A C  P   G+CRA+F R++YD    +CE F YGGCGGN NNF+++E+C+++CMK+
Sbjct:   28 ASCRLPAVVGQCRASFPRYFYDSKVNRCEPFVYGGCGGNANNFESVEQCENVCMKS 83

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: R4FK61 (KP-Pse-5 OS=Pseudonaja modesta OX=340912 PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.658e-13
Identity = 30/52 (57.69%), Postives = 37/52 (71.15%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C+ P + GRC A+  RFYY+    QC  F YGGCGGN NNF+TI+ECKS C+
Sbjct:   31 CELPAETGRCNAHITRFYYNPRQHQCIKFLYGGCGGNANNFKTIKECKSTCI 82

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: A0A2G9QFZ7 (Uncharacterized protein OS=Lithobates catesbeianus OX=8400 GN=AB205_0191710 PE=4 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.957e-13
Identity = 30/52 (57.69%), Postives = 39/52 (75.00%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            C+ P+DPG C+A+ +R+YYDQ    C+ F YGGC GN NNF+T EECK IC+
Sbjct:  139 CEQPRDPGPCKAHVKRYYYDQETDTCKDFIYGGCEGNRNNFKTEEECKRICI 190

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: A0A0K8TJB8 (Uncharacterized protein (Fragment) OS=Lygus hesperus OX=30085 PE=4 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 2.369e-13
Identity = 31/54 (57.41%), Postives = 40/54 (74.07%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C  P+ PG C+A FRR+Y+D  ++QC  F+YGGC GNGNNFQT EEC+  C +N
Sbjct:  191 CLLPQAPGLCKAAFRRYYFDASSQQCVLFTYGGCMGNGNNFQTKEECEQTCAQN 244

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: wfikkn2a (WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2-like [Source:NCBI gene;Acc:103032076])

HSP 1 Score: 64.3142 bits (155), Expect = 4.978e-13
Identity = 28/60 (46.67%), Postives = 39/60 (65.00%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            SCG+   A C  P   G C+A   R+ Y+ + KQC++F YGGCGGN NNF++ E C+ +C
Sbjct:  368 SCGAELAAPCSLPSLQGPCKAYEPRWAYNHLLKQCQSFVYGGCGGNENNFESKEACEEMC 427

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: appb (amyloid beta A4 protein-like [Source:NCBI gene;Acc:103046668])

HSP 1 Score: 61.2326 bits (147), Expect = 4.925e-12
Identity = 25/53 (47.17%), Postives = 33/53 (62.26%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            A C AP   G CRA   R+Y+     +C  FS+GGCGGN NNF++ E C ++C
Sbjct:  309 AVCWAPPRRGPCRATLSRWYFVAETGRCAPFSFGGCGGNRNNFESEEYCMAVC 361

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: appb (amyloid beta A4 protein-like [Source:NCBI gene;Acc:103046668])

HSP 1 Score: 61.2326 bits (147), Expect = 5.009e-12
Identity = 25/53 (47.17%), Postives = 33/53 (62.26%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            A C AP   G CRA   R+Y+     +C  FS+GGCGGN NNF++ E C ++C
Sbjct:  309 AVCWAPPRRGPCRATLSRWYFVAETGRCAPFSFGGCGGNRNNFESEEYCMAVC 361

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:103023332])

HSP 1 Score: 60.077 bits (144), Expect = 6.849e-12
Identity = 25/51 (49.02%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  P   G CR    R++Y+ + ++CE FSYGGCGGN NNF T +EC  +C
Sbjct:   27 CLLPAVEGPCRGLVSRYFYNTLTQRCEEFSYGGCGGNANNFVTFQECHKMC 77

HSP 2 Score: 53.5286 bits (127), Expect = 1.717e-9
Identity = 23/51 (45.10%), Postives = 30/51 (58.82%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  P + G CRA   R++++    QCE F YGGC GN NNFQ+ + C   C
Sbjct:   87 CRFPSEVGPCRALLSRYFFNMTTMQCEQFYYGGCQGNENNFQSHQSCMEYC 137

HSP 3 Score: 52.373 bits (124), Expect = 3.798e-9
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C    D G+C A+  R+YY+   K CE F+Y GCGG+ NNF + + C  +C +
Sbjct:  147 CQGVLDKGKCSASIPRYYYNSAKKTCEEFTYTGCGGSSNNFVSKQSCMDVCAR 199

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: ENSAMXT00000056342.1 (pep primary_assembly:Astyanax_mexicanus-2.0:25:41015233:41016395:-1 gene:ENSAMXG00000036709.1 transcript:ENSAMXT00000056342.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 7.590e-12
Identity = 24/54 (44.44%), Postives = 35/54 (64.81%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
             C  P D G+C     ++++D   ++C  F YGGCGGNGN F+T EEC++ C+K
Sbjct:   36 HCKLPHDLGKCYNFALKWHFDTSIQECTRFWYGGCGGNGNRFETQEECEARCLK 89

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 61.2326 bits (147), Expect = 6.169e-13
Identity = 24/53 (45.28%), Postives = 36/53 (67.92%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
              C  P  PG CRA F R+++++   +CE+F YGGC  N NNF+T++EC++ C
Sbjct:   25 VTCTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAAC 77

HSP 2 Score: 58.151 bits (139), Expect = 7.337e-12
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            +C +  D G C+ NFRRFYY+   + C  FSY GCGGN NNF + + C S C+
Sbjct:  146 ECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTCL 198

HSP 3 Score: 51.9878 bits (123), Expect = 1.451e-9
Identity = 22/53 (41.51%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C    + GRCRA+  R++Y+     C  F YGGCGGN N F+ +E C   C++
Sbjct:   87 CRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSCIE 139

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 3.785e-12
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            + C    DPG CRA   R +Y++  ++CE F YGGC GNGNNF+++ EC + C
Sbjct:    1 SSCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 2 Score: 56.225 bits (134), Expect = 3.299e-11
Identity = 25/51 (49.02%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C    DPG C A   RF+Y+     CE+F+YGGCGGN NNF +   C S+C
Sbjct:  166 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 216

HSP 3 Score: 46.595 bits (109), Expect = 9.487e-8
Identity = 22/61 (36.07%), Postives = 31/61 (50.82%), Query Frame = 1

Query:   91 CGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C   +   C    + G CRA  RR++++  +  CE F YGGC GN NNF+    C   C+ 
Sbjct:   66 CPLVAPKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHCVH 126

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.5362 bits (140), Expect = 4.325e-12
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  109 ADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            + C    DPG CRA   R +Y++  ++CE F YGGC GNGNNF+++ EC + C
Sbjct:    1 SSCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 2 Score: 56.225 bits (134), Expect = 3.921e-11
Identity = 25/51 (49.02%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C    DPG C A   RF+Y+     CE+F+YGGCGGN NNF +   C S+C
Sbjct:  167 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 217

HSP 3 Score: 46.595 bits (109), Expect = 1.153e-7
Identity = 21/53 (39.62%), Postives = 29/53 (54.72%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C    + G CRA  RR++++  +  CE F YGGC GN NNF+    C   C+ 
Sbjct:   75 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHCVH 127

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005252.1 (pep scaffold:Pmarinus_7.0:GL477257:283672:285029:-1 gene:ENSPMAG00000004785.1 transcript:ENSPMAT00000005252.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 5.701e-10
Identity = 21/51 (41.18%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  P D G C  +  R +++  N  CE+F Y GCGGNGN+F + + C+ +C
Sbjct:   65 CKLPADSGPCEESTYRIHFNASNGLCESFPYSGCGGNGNSFPSTQACQRLC 115

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008261.1 (pep scaffold:Pmarinus_7.0:GL478901:735:1448:1 gene:ENSPMAG00000007479.1 transcript:ENSPMAT00000008261.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.2914 bits (116), Expect = 9.198e-9
Identity = 23/60 (38.33%), Postives = 34/60 (56.67%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +C + +   C  P   G C+A   R+ Y+ + K+C TF YGGC GNGN+F +   C+  C
Sbjct:   12 ACVNETARVCSLPPVQGPCKAWETRWSYNPLGKRCATFLYGGCEGNGNSFASRSACERAC 71

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 64.6994 bits (156), Expect = 1.647e-15
Identity = 30/61 (49.18%), Postives = 37/61 (60.66%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICM 270
            S   S  + C  PK  G CRA   R +++  + +CE F YGGCGGN NNF T+EECK  CM
Sbjct:    5 SAAVSGNSACTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKACM 65

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO31760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX09])

HSP 1 Score: 64.3142 bits (155), Expect = 2.321e-15
Identity = 26/53 (49.06%), Postives = 38/53 (71.70%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            CD PK+PG CRA+ +R+YY+   ++C  F++GGC GN NNF T   C++ CM+
Sbjct:    1 CDLPKNPGVCRASIQRWYYNNETRKCIKFTFGGCHGNANNFPTKSSCRNACMR 53

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 58.151 bits (139), Expect = 4.654e-13
Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +C  PK  G CRA F R++Y+Q +++C+ F YGGC GN NNF++  EC+  C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 58.151 bits (139), Expect = 4.654e-13
Identity = 25/52 (48.08%), Postives = 36/52 (69.23%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +C  PK  G CRA F R++Y+Q +++C+ F YGGC GN NNF++  EC+  C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO41921 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S321])

HSP 1 Score: 55.0694 bits (131), Expect = 6.525e-12
Identity = 25/46 (54.35%), Postives = 31/46 (67.39%), Query Frame = 1

Query:  130 DPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            DPG C+A   RFY++   K+C+ F YGGCGGN N F T  EC+ IC
Sbjct:    1 DPGPCKAYMPRFYFEIEKKECQEFIYGGCGGNENRFFTKRECQRIC 46

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:101174930])

HSP 1 Score: 64.6994 bits (156), Expect = 2.298e-13
Identity = 27/53 (50.94%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  P D G+C A+ RRFYY++  K CE F+Y GCGG+ NNF + E C+ +C+K
Sbjct:  204 CLDPLDKGKCSASMRRFYYNKATKTCEEFAYSGCGGSSNNFVSRESCEDVCLK 256

HSP 2 Score: 56.9954 bits (136), Expect = 1.327e-10
Identity = 24/51 (47.06%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C  PK+ G CRA F  ++++    QCE FSYGGCGGN N F+ +  C   C
Sbjct:  144 CRFPKEEGHCRALFPSYFFNMSTMQCEPFSYGGCGGNSNRFRDLTSCMDFC 194

HSP 3 Score: 55.0694 bits (131), Expect = 5.619e-10
Identity = 21/53 (39.62%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C    D G CR    R++Y+ + ++CE F YGGC GN NNF + ++C+  C +
Sbjct:   84 CLLRVDEGPCRGQIERYFYNTITQKCEVFYYGGCHGNANNFMSFQKCQKTCFR 136

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: COL6A3 (collagen type VI alpha 3 chain [Source:NCBI gene;Acc:101161016])

HSP 1 Score: 60.8474 bits (146), Expect = 7.175e-12
Identity = 26/53 (49.06%), Postives = 29/53 (54.72%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            C  PK  G C     ++YYD  +K C  F YGGC GN N F T EECK  C K
Sbjct: 2639 CQLPKQEGSCAEFALKWYYDTTSKSCTRFWYGGCDGNQNRFDTQEECKEACEK 2691

HSP 2 Score: 46.2098 bits (108), Expect = 9.705e-7
Identity = 21/55 (38.18%), Postives = 30/55 (54.55%), Query Frame = 1

Query:  115 CDAPKDPGR-CRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            C    DPG  C+    ++YY++ N  C  F YGGCGGN N F +   C   C+++
Sbjct: 2551 CSLGFDPGMPCKDYQAKWYYERQNGFCTQFWYGGCGGNDNRFDSEALCLKRCLRS 2605

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: ENSORLT00000029380.1 (pep primary_assembly:ASM223467v1:16:32225490:32229522:1 gene:ENSORLG00000025276.1 transcript:ENSORLT00000029380.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 2.559e-11
Identity = 26/63 (41.27%), Postives = 36/63 (57.14%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            S  S SG  C  P D G C+     +++D    +C  F YGGCGGN N F T EEC+++C++ 
Sbjct:   74 SLASGSGDACRQPLDQGSCQTYAMMWFFDSNETKCAPFWYGGCGGNQNRFSTEEECQTVCLEG 136

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: APP (amyloid-beta A4 protein [Source:NCBI gene;Acc:101162104])

HSP 1 Score: 59.3066 bits (142), Expect = 2.796e-11
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  115 CDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            C A  + G CRA   R+++D+   +C  F YGGCGGN NNF++ E C S+C
Sbjct:  330 CWADAETGPCRALLPRWFFDREEGRCVQFIYGGCGGNRNNFESEEYCMSVC 380

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: wfikkn2a (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:NCBI gene;Acc:101168544])

HSP 1 Score: 58.5362 bits (140), Expect = 4.698e-11
Identity = 26/60 (43.33%), Postives = 36/60 (60.00%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSIC 267
            +CG    A C  P   G C+A   R+ Y    K+C++F YGGCGGN NNF++ E C+ +C
Sbjct:  379 ACGGELAAPCSLPSLQGPCKAYEPRWAYSSTLKKCQSFVYGGCGGNENNFESKEACEQMC 438

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000044322.1 (SMESG000044322.1)

HSP 1 Score: 131.724 bits (330), Expect = 1.571e-41
Identity = 62/63 (98.41%), Postives = 63/63 (100.00%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMKN 276
            SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQ+IEECKSICMKN
Sbjct:   20 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQSIEECKSICMKN 82

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.750e-17
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 1

Query:   97 SSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
             S   +C+ PK  G C A F+RFY++    +CETF YGGCG NGNNFQT +EC+ +C++
Sbjct:   21 ESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 79

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.850e-17
Identity = 29/54 (53.70%), Postives = 40/54 (74.07%), Query Frame = 1

Query:  112 DCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            +C+ PK  G C A F+RFY++    +CETF YGGCG NGNNFQT +EC+ +C++
Sbjct:   24 ECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 77

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000037995.1 (SMESG000037995.1)

HSP 1 Score: 70.0922 bits (170), Expect = 3.346e-17
Identity = 30/59 (50.85%), Postives = 41/59 (69.49%), Query Frame = 1

Query:   97 SSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
             S   +C+ PK  G C A F+RFY++    +CETF YGGCG NGNNFQT +EC+ +C++
Sbjct:   21 ESRLKECNEPKQSGMCMAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 79

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000037994.1 (SMESG000037994.1)

HSP 1 Score: 68.1662 bits (165), Expect = 1.856e-16
Identity = 31/62 (50.00%), Postives = 41/62 (66.13%), Query Frame = 1

Query:   88 SCGSSSGADCDAPKDPGRCRANFRRFYYDQVNKQCETFSYGGCGGNGNNFQTIEECKSICMK 273
            S G S   +C+ PK  G C A F RFY++  +  CE+F YGGC  NGNNF TIEEC++ C++
Sbjct:   16 SLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 77

The following BLAST results are available for this feature:

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
BLAST of Kunitz-type protease inhibitor vs. TrEMBL
BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
BLAST of Kunitz-type protease inhibitor vs. Ensembl Yeast
BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TFPI	6.484e-14	56.86	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	6.484e-14	56.86	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	8.387e-14	56.86	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	1.961e-13	56.86	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	1.961e-13	56.86	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	9.424e-13	50.94	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	9.464e-13	50.94	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	9.465e-13	50.94	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	9.609e-13	50.94	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	9.670e-13	50.94	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG3604	1.962e-13	49.06	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	1.962e-13	49.06	gene:FBgn0031562 transcript:FBtr0346581	[more]
CG17380	3.148e-11	50.98	gene:FBgn0039077 transcript:FBtr0299867	[more]
CG15418	1.290e-10	45.28	gene:FBgn0031554 transcript:FBtr0077556	[more]
CG15418	1.290e-10	45.28	gene:FBgn0031554 transcript:FBtr0446100	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spint1b	2.772e-12	49.06	serine peptidase inhibitor, Kunitz type 1 b [Sourc...	[more]
appa	4.289e-12	49.02	amyloid beta (A4) precursor protein a [Source:ZFIN...	[more]
wfikkn2a	6.366e-12	45.00	info WAP, follistatin/kazal, immunoglobulin, kunit...	[more]
tfpia	3.141e-11	48.08	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
tfpia	3.352e-11	48.08	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
itch	3.644e-12	48.08	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
itch	3.896e-12	48.08	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
itch	3.900e-12	48.08	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
tfpi2	1.071e-11	50.94	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
spint2	1.644e-11	50.98	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tfpi2	8.318e-15	54.72	tissue factor pathway inhibitor 2 [Source:MGI Symb...	[more]
Tfpi	3.600e-14	48.44	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	3.600e-14	48.44	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	3.600e-14	48.44	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	5.872e-14	48.44	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DN13\|VKT9_ANEVI	4.222e-18	59.62	U-actitoxin-Avd3l OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|Q9TWF8\|VKT3_ANESU	5.135e-18	58.49	KappaPI-actitoxin-Avd3d OS=Anemonia sulcata OX=610...	[more]
sp\|P0DN07\|VKT4_ANEVI	7.526e-18	59.62	U-actitoxin-Avd3g OS=Anemonia viridis OX=51769 PE=...	[more]
sp\|P10280\|VKT52_ANESU	2.940e-17	58.49	KappaPI-actitoxin-Avd3a OS=Anemonia sulcata OX=610...	[more]
sp\|P0DN08\|VKT53_ANEVI	3.174e-17	59.62	KappaPI-actitoxin-Avd3e OS=Anemonia viridis OX=517...	[more]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0C2CY52	2.571e-15	53.97	Kunitz/Bovine pancreatic trypsin inhibitor domain ...	[more]
A0A4S2L009	2.319e-14	51.79	BPTI/Kunitz inhibitor domain-containing protein OS...	[more]
R4FK61	1.658e-13	57.69	KP-Pse-5 OS=Pseudonaja modesta OX=340912 PE=2 SV=1	[more]
A0A2G9QFZ7	1.957e-13	57.69	Uncharacterized protein OS=Lithobates catesbeianus...	[more]
A0A0K8TJB8	2.369e-13	57.41	Uncharacterized protein (Fragment) OS=Lygus hesper...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wfikkn2a	4.978e-13	46.67	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-...	[more]
appb	4.925e-12	47.17	amyloid beta A4 protein-like [Source:NCBI gene;Acc...	[more]
appb	5.009e-12	47.17	amyloid beta A4 protein-like [Source:NCBI gene;Acc...	[more]
tfpi2	6.849e-12	49.02	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
ENSAMXT00000056342.1	7.590e-12	44.44	pep primary_assembly:Astyanax_mexicanus-2.0:25:410...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	6.169e-13	45.28	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000005043.1	3.785e-12	47.17	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005038.1	4.325e-12	47.17	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005252.1	5.701e-10	41.18	pep scaffold:Pmarinus_7.0:GL477257:283672:285029:-...	[more]
ENSPMAT00000008261.1	9.198e-9	38.33	pep scaffold:Pmarinus_7.0:GL478901:735:1448:1 gene...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO29819	1.647e-15	49.18	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31760	2.321e-15	49.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	4.654e-13	48.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	4.654e-13	48.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41921	6.525e-12	54.35	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	2.298e-13	50.94	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
COL6A3	7.175e-12	49.06	collagen type VI alpha 3 chain [Source:NCBI gene;A...	[more]
ENSORLT00000029380.1	2.559e-11	41.27	pep primary_assembly:ASM223467v1:16:32225490:32229...	[more]
APP	2.796e-11	47.06	amyloid-beta A4 protein [Source:NCBI gene;Acc:1011...	[more]
wfikkn2a	4.698e-11	43.33	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000044322.1	1.571e-41	98.41	SMESG000044322.1	[more]
SMESG000037999.1	2.750e-17	50.85	SMESG000037999.1	[more]
SMESG000037999.1	2.850e-17	53.70	SMESG000037999.1	[more]
SMESG000037995.1	3.346e-17	50.85	SMESG000037995.1	[more]
SMESG000037994.1	1.856e-16	50.00	SMESG000037994.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30012509 ID=SMED30012509|Name=Kunitz-type protease inhibitor|organism=Schmidtea mediterranea sexual|type=transcript|length=321bp
TCCTCCAAAAAAATTATTTCCTTCAACATGTTCAAATCAAAAAATTGCAT
TTTTACTTTTTTTATTTTATTCTGATTGAAAATACTCAGTTGCGGTTCAA
GTTCTGGTGCCGATTGTGATGCTCCAAAAGATCCTGGGAGATGTCGAGCA
AATTTTCGACGATTTTACTACGACCAAGTCAACAAGCAATGCGAAACATT
TTCATACGGCGGATGTGGAGGAAATGGCAACAATTTTCAGACAATTGAAG
AATGCAAATCCATTTGCATGAAAAACTAAAGCAGAAAATTTATATTTATT
AATTGTATCATTAAAAAATTT

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

Vocabulary: **molecular function**
Term	Definition
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0030414	peptidase inhibitor activity

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region

Vocabulary: **biological process**
Term	Definition
GO:0010466	negative regulation of peptidase activity
GO:0010951	negative regulation of endopeptidase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	TMHMM	TMhelix		coord: 13..35

Main menu

Kunitz-type protease inhibitor

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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