Plastin-2

Overview


Name	Plastin-2
Smed ID	SMED30012493
Length (bp)	666

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Plastin-2 (SMED30012493) t-SNE clustered cells

Violin plots show distribution of expression levels for Plastin-2 (SMED30012493) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Plastin-2 (SMED30012493) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Plastin-2 (SMED30012493) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012493

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30012493	SMESG000007726.1	dd_Smed_v4_11520_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30012493	SMESG000007726.1	dd_Smed_v4_11520_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30012493	SMESG000007726.1	Contig48975	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30012493	SMESG000007726.1	Contig48975	uc_Smed_v2	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Plastin-2 vs. Ensembl Human
Match: PLS3 (plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091])

HSP 1 Score: 150.984 bits (380), Expect = 9.817e-42
Identity = 90/226 (39.82%), Postives = 137/226 (60.62%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + ++   L L +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  405 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 628

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Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + ++   L L +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  405 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 628

[Close]

BLAST of Plastin-2 vs. Ensembl Human
Match: PLS3 (plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091])

HSP 1 Score: 150.599 bits (379), Expect = 9.924e-42
Identity = 90/226 (39.82%), Postives = 137/226 (60.62%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + ++   L L +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  392 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 615

[Close]

BLAST of Plastin-2 vs. Ensembl Human
Match: PLS3 (plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091])

HSP 1 Score: 150.599 bits (379), Expect = 1.013e-41
Identity = 90/226 (39.82%), Postives = 137/226 (60.62%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + ++   L L +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  392 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 615

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BLAST of Plastin-2 vs. Ensembl Human
Match: PLS1 (plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090])

HSP 1 Score: 144.05 bits (362), Expect = 2.954e-39
Identity = 88/225 (39.11%), Postives = 132/225 (58.67%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGL 651
            NW+NS G+   +N  Y D  D LV   +++ +    VNWS V +  + +     ++  NCN  +E GK K    +  ++G+++   +    L L +Q+MR  T+ VL  L  G K  D+  I  WVN TL+ A K + I+SFKD++I+TSLPV+DL+DAI P +V+  +I        D+L +A YA+S+ARKIGA  + LPD +  +  KM+MT+FA LM  GL
Sbjct:  403 NWMNSLGVNPYINHLYSDLADALVIFQLYEMIRV-PVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIII-KWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKGL 625

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BLAST of Plastin-2 vs. Ensembl Celegans
Match: plst-1 (PLaSTin (Actin bundling protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PMA7])

HSP 1 Score: 154.451 bits (389), Expect = 3.059e-45
Identity = 82/219 (37.44%), Postives = 130/219 (59.36%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXX-XXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  +G+V   ++D + PG V W +VVR F   R +  +  NCN  +E GK+    +  + G++I + ++   L L +Q+MR  T+ VL +          DKDI++WVN+ L+ +GK++ I SF+D  I+    V+DL+DAIKP  + +SL+ S     D++ +A YA++  RKIGA  + LP+ I  +  KM++T+FA LM
Sbjct:  125 NWMNSMGVDPYVNWLYADLQNGVVIFQLYDIIRPGMVTWKRVVRTFHKLRGMMDQIQNCNYAVELGKQLRFSLVGIQGKDIYDGNQTLTLALVWQLMRAYTLSVLAQCTQSGDSLPADKDIVAWVNEKLKNSGKSTSIRSFQDPAISDGKVVLDLIDAIKPNVIDHSLVKSGKSNEDKMSNAKYAITCGRKIGAKIYALPEDIVEVKPKMVLTVFACLM 343

[Close]

BLAST of Plastin-2 vs. Ensembl Celegans
Match: plst-1 (PLaSTin (Actin bundling protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PMA7])

HSP 1 Score: 154.451 bits (389), Expect = 3.481e-45
Identity = 83/219 (37.90%), Postives = 131/219 (59.82%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXX-XXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  +G+V   ++D + PG V W +VVR F   R +  +  NCN  +E GK+    +  + G++I + ++   L L +Q+MR  T+ VL +    G     DKDI++WVN+ L+ +GK++ I SF+D  I+    V+DL+DAIKP  + +SL+ S     D++ +A YA++  RKIGA  + LP+ I  +  KM++T+FA LM
Sbjct:  128 NWMNSMGVDPYVNWLYADLQNGVVIFQLYDIIRPGMVTWKRVVRTFHKLRGMMDQIQNCNYAVELGKQLRFSLVGIQGKDIYDGNQTLTLALVWQLMRAYTLSVLAQCTQSGDSLPADKDIVAWVNEKLKNSGKSTSIRSFQDPAISDGKVVLDLIDAIKPNVIDHSLVKSGKSNEDKMSNAKYAITCGRKIGAKIYALPEDIVEVKPKMVLTVFACLM 346

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BLAST of Plastin-2 vs. Ensembl Celegans
Match: Y73B3B.1 (pep chromosome:WBcel235:X:209108:211241:-1 gene:WBGene00022223.1 transcript:Y73B3B.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y73B3B.1)

HSP 1 Score: 97.8265 bits (242), Expect = 9.300e-24
Identity = 56/183 (30.60%), Postives = 100/183 (54.64%), Query Frame = 1

Query:  109 VNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXX-XSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            ++  K +  F S       +G+ +      ++C        G +I + +++  L L +Q+MR  T+ VL +    G  +      ++WVN+ L+ +GK++ I SF+D  I+    V+DL+D+IKP  + +SL+ S     D++ +A YA++  RKIGA  + LP+ I  +  KM++T+FA LM
Sbjct:  170 LDEGKRISKFTSTDGKLNLEGDHSHAARMKRRCAEYRNAYRGRHIYDGNQILTLALVWQLMRAYTLSVLAQYTQSGDSLPTDKDIVAWVNEKLKNSGKSTSIRSFQDPAISDGKVVLDLIDSIKPNVIDHSLVKSGKSNEDKMSNAKYAITCGRKIGAKIYALPEDIVEVKPKMVLTVFACLM 352

[Close]

BLAST of Plastin-2 vs. Ensembl Fly
Match: Fim (gene:FBgn0024238 transcript:FBtr0074442)

HSP 1 Score: 174.866 bits (442), Expect = 5.507e-51
Identity = 89/218 (40.83%), Postives = 134/218 (61.47%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  DGLV   +FD + PG VNWS+V + F   R+  ++  NCN  ++ GK+    +  ++G+++ + +    L L +Q+MR  T+ +L +L   G  I +K+I+ WVN+ L +AGK S++ +F D  IA    VIDL+DAIK GS+ Y L+ +     D L +A YA+SMARKIGA  + LP+ I  +  KM+MT+FA +M
Sbjct:  375 NWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKRFSPLRKFMEKLENCNYAVDLGKQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMM 592

[Close]

BLAST of Plastin-2 vs. Ensembl Fly
Match: Fim (gene:FBgn0024238 transcript:FBtr0074443)

HSP 1 Score: 175.252 bits (443), Expect = 6.700e-51
Identity = 89/218 (40.83%), Postives = 134/218 (61.47%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  DGLV   +FD + PG VNWS+V + F   R+  ++  NCN  ++ GK+    +  ++G+++ + +    L L +Q+MR  T+ +L +L   G  I +K+I+ WVN+ L +AGK S++ +F D  IA    VIDL+DAIK GS+ Y L+ +     D L +A YA+SMARKIGA  + LP+ I  +  KM+MT+FA +M
Sbjct:  400 NWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKRFSPLRKFMEKLENCNYAVDLGKQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMM 617

[Close]

BLAST of Plastin-2 vs. Ensembl Fly
Match: Fim (gene:FBgn0024238 transcript:FBtr0074441)

HSP 1 Score: 174.866 bits (442), Expect = 7.263e-51
Identity = 89/218 (40.83%), Postives = 134/218 (61.47%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  DGLV   +FD + PG VNWS+V + F   R+  ++  NCN  ++ GK+    +  ++G+++ + +    L L +Q+MR  T+ +L +L   G  I +K+I+ WVN+ L +AGK S++ +F D  IA    VIDL+DAIK GS+ Y L+ +     D L +A YA+SMARKIGA  + LP+ I  +  KM+MT+FA +M
Sbjct:  399 NWMNSMGVAPHVNWLYSDLADGLVIFQLFDVIKPGIVNWSRVHKRFSPLRKFMEKLENCNYAVDLGKQLKFSLVGIAGQDLNDGNATLTLALIWQLMRAYTLSILSRLANTGNPIIEKEIVQWVNNRLSEAGKQSQLRNFNDPAIADGKIVIDLIDAIKEGSINYELVRTSGTQEDNLANAKYAISMARKIGARVYALPEDITEVKPKMVMTVFACMM 616

[Close]

BLAST of Plastin-2 vs. Ensembl Zebrafish
Match: pls3 (plastin 3 (T isoform) [Source:ZFIN;Acc:ZDB-GENE-040718-10])

HSP 1 Score: 154.066 bits (388), Expect = 4.217e-43
Identity = 93/228 (40.79%), Postives = 140/228 (61.40%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++K+    V+W+  V N     +L    ++  NCN  +E GK K N  +  + G+++ + +    L L +Q+MR  T+ VLE L  G K  DD  + SWVN TL +AGK+++I++FKD+ I++SL V+DL+DAI+P S+ Y L+        D+L +A YAVSMARKIGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  401 NWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKV-PVDWNNKV-NKPPYPKLGANMKKLENCNYAVELGKTKANFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLENLGDGQKVNDDVIV-SWVNKTLSQAGKSTKISNFKDKEISSSLAVLDLIDAIQPSSINYDLVKRGSLSDGDKLDNAKYAVSMARKIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 625

[Close]

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++K+    V+W+  V N     +L    ++  NCN  +E GK K N  +  + G+++ + +    L L +Q+MR  T+ VLE L  G K  DD  + SWVN TL +AGK+++I++FKD+ I++SL V+DL+DAI+P S+ Y L+        D+L +A YAVSMARKIGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  401 NWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKV-PVDWNNKV-NKPPYPKLGANMKKLENCNYAVELGKTKANFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLENLGDGQKVNDDVIV-SWVNKTLSQAGKSTKISNFKDKEISSSLAVLDLIDAIQPSSINYDLVKRGSLSDGDKLDNAKYAVSMARKIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 625

[Close]

BLAST of Plastin-2 vs. Ensembl Zebrafish
Match: pls1 (plastin 1 (I isoform) [Source:ZFIN;Acc:ZDB-GENE-030131-6205])

HSP 1 Score: 151.754 bits (382), Expect = 3.091e-42
Identity = 91/227 (40.09%), Postives = 136/227 (59.91%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLN-PGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  DGL+ L +++++  P  V+W +V +  +       ++  NCN  +  GKK     +  + GENI     ++ L L +Q+MR  T+KVL  L  G K  D   I +WVN TL++  K S I+SFKD++I+TSLPVIDL+D I P +++Y ++ S      D+L +A YA+S+ARKIG   + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  401 NWMNSLGVSPYVNHLYSDLHDGLIILQLYERIQIP--VDWPRVNKPPYPVLGSNMKKLENCNYAVALGKKEAKFSLVGIGGENINEGSPMHTLALVWQLMRRYTLKVLSDLGDGEKVSDQIII-NWVNSTLKQGDKNSSISSFKDKSISTSLPVIDLIDTIVPKAIKYEMVKSGDMTAEDKLNNAKYAISVARKIGVKVYALPDDLVEVKPKMVMTVFACLMGRGLK 624

[Close]

BLAST of Plastin-2 vs. Ensembl Zebrafish
Match: pls1 (plastin 1 (I isoform) [Source:ZFIN;Acc:ZDB-GENE-030131-6205])

HSP 1 Score: 151.754 bits (382), Expect = 4.272e-42
Identity = 91/227 (40.09%), Postives = 136/227 (59.91%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLN-PGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  DGL+ L +++++  P  V+W +V +  +       ++  NCN  +  GKK     +  + GENI     ++ L L +Q+MR  T+KVL  L  G K  D   I +WVN TL++  K S I+SFKD++I+TSLPVIDL+D I P +++Y ++ S      D+L +A YA+S+ARKIG   + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  438 NWMNSLGVSPYVNHLYSDLHDGLIILQLYERIQIP--VDWPRVNKPPYPVLGSNMKKLENCNYAVALGKKEAKFSLVGIGGENINEGSPMHTLALVWQLMRRYTLKVLSDLGDGEKVSDQIII-NWVNSTLKQGDKNSSISSFKDKSISTSLPVIDLIDTIVPKAIKYEMVKSGDMTAEDKLNNAKYAISVARKIGVKVYALPDDLVEVKPKMVMTVFACLMGRGLK 661

[Close]

BLAST of Plastin-2 vs. Ensembl Zebrafish
Match: lcp1 (lymphocyte cytosolic protein 1 (L-plastin) [Source:NCBI gene;Acc:30583])

HSP 1 Score: 151.369 bits (381), Expect = 4.521e-42
Identity = 88/225 (39.11%), Postives = 139/225 (61.78%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGL 651
            NW+NS G+  +VN  Y D  D LV   +++K+    V+W KV +  +       ++  NCN  +E GKK     +  ++G+++   ++   L L +Q+MR  T+ +LE L  G K ID+  +  WVN+TL +AGK + I+ FKD +I++S+PV+DL+DAI+PGS++Y L+ ++ L D      A YA+SMARKIGA  + LP+ +  +  KM+MT+FA LM  G+
Sbjct:  400 NWMNSLGVNPRVNHLYVDLADALVIFQLYEKIKV-PVDWDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLGDGQKIIDETIV-QWVNETLTQAGKGT-ISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLKAEDLTDEEKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARGM 621

[Close]

BLAST of Plastin-2 vs. Ensembl Xenopus
Match: snx5 (sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018])

HSP 1 Score: 153.295 bits (386), Expect = 3.815e-43
Identity = 90/226 (39.82%), Postives = 148/226 (65.49%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSK-RRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V +   SK     ++  NCN  ++ GK K    +  ++G++++  +    L L +Q+MR  T+ +LE + GGG+K++D+ I++WVN+TL++A K S I+SFKD  I+TS+PV+DL+DAI+PG + Y L+       +++L +A YA+SMARK+GA  + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  309 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VDWNRVNKPPYSKLGENMKKIENCNYAVDLGKNKAKFSLVGIAGQDLKEGNHTLTLALLWQLMRRYTLNILEDI-GGGQKVNDETILTWVNETLKEAEKCSSISSFKDPKISTSMPVLDLIDAIQPGCINYDLLKTEDLDETEKLNNAKYAISMARKVGARVYALPDDLVEVKPKMVMTVFACLMGRGLK 532

[Close]

BLAST of Plastin-2 vs. Ensembl Xenopus
Match: snx5 (sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018])

HSP 1 Score: 153.68 bits (387), Expect = 3.928e-43
Identity = 90/226 (39.82%), Postives = 148/226 (65.49%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSK-RRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V +   SK     ++  NCN  ++ GK K    +  ++G++++  +    L L +Q+MR  T+ +LE + GGG+K++D+ I++WVN+TL++A K S I+SFKD  I+TS+PV+DL+DAI+PG + Y L+       +++L +A YA+SMARK+GA  + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  320 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VDWNRVNKPPYSKLGENMKKIENCNYAVDLGKNKAKFSLVGIAGQDLKEGNHTLTLALLWQLMRRYTLNILEDI-GGGQKVNDETILTWVNETLKEAEKCSSISSFKDPKISTSMPVLDLIDAIQPGCINYDLLKTEDLDETEKLNNAKYAISMARKVGARVYALPDDLVEVKPKMVMTVFACLMGRGLK 543

[Close]

BLAST of Plastin-2 vs. Ensembl Xenopus
Match: snx5 (sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018])

HSP 1 Score: 153.295 bits (386), Expect = 7.246e-43
Identity = 90/226 (39.82%), Postives = 148/226 (65.49%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSK-RRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V +   SK     ++  NCN  ++ GK K    +  ++G++++  +    L L +Q+MR  T+ +LE + GGG+K++D+ I++WVN+TL++A K S I+SFKD  I+TS+PV+DL+DAI+PG + Y L+       +++L +A YA+SMARK+GA  + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  347 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VDWNRVNKPPYSKLGENMKKIENCNYAVDLGKNKAKFSLVGIAGQDLKEGNHTLTLALLWQLMRRYTLNILEDI-GGGQKVNDETILTWVNETLKEAEKCSSISSFKDPKISTSMPVLDLIDAIQPGCINYDLLKTEDLDETEKLNNAKYAISMARKVGARVYALPDDLVEVKPKMVMTVFACLMGRGLK 570

[Close]

BLAST of Plastin-2 vs. Ensembl Xenopus
Match: snx5 (sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018])

HSP 1 Score: 153.295 bits (386), Expect = 9.848e-43
Identity = 90/226 (39.82%), Postives = 148/226 (65.49%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSK-RRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V +   SK     ++  NCN  ++ GK K    +  ++G++++  +    L L +Q+MR  T+ +LE + GGG+K++D+ I++WVN+TL++A K S I+SFKD  I+TS+PV+DL+DAI+PG + Y L+       +++L +A YA+SMARK+GA  + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  383 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VDWNRVNKPPYSKLGENMKKIENCNYAVDLGKNKAKFSLVGIAGQDLKEGNHTLTLALLWQLMRRYTLNILEDI-GGGQKVNDETILTWVNETLKEAEKCSSISSFKDPKISTSMPVLDLIDAIQPGCINYDLLKTEDLDETEKLNNAKYAISMARKVGARVYALPDDLVEVKPKMVMTVFACLMGRGLK 606

[Close]

BLAST of Plastin-2 vs. Ensembl Xenopus
Match: snx5 (sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018])

HSP 1 Score: 153.295 bits (386), Expect = 9.971e-43
Identity = 90/226 (39.82%), Postives = 148/226 (65.49%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSK-RRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V +   SK     ++  NCN  ++ GK K    +  ++G++++  +    L L +Q+MR  T+ +LE + GGG+K++D+ I++WVN+TL++A K S I+SFKD  I+TS+PV+DL+DAI+PG + Y L+       +++L +A YA+SMARK+GA  + LPD +  +  KM+MT+FA LM  GL+
Sbjct:  403 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVP-VDWNRVNKPPYSKLGENMKKIENCNYAVDLGKNKAKFSLVGIAGQDLKEGNHTLTLALLWQLMRRYTLNILEDI-GGGQKVNDETILTWVNETLKEAEKCSSISSFKDPKISTSMPVLDLIDAIQPGCINYDLLKTEDLDETEKLNNAKYAISMARKVGARVYALPDDLVEVKPKMVMTVFACLMGRGLK 626

[Close]

BLAST of Plastin-2 vs. Ensembl Mouse
Match: Lcp1 (lymphocyte cytosolic protein 1 [Source:MGI Symbol;Acc:MGI:104808])

HSP 1 Score: 152.91 bits (385), Expect = 1.228e-42
Identity = 92/228 (40.35%), Postives = 147/228 (64.47%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V  N     +L    ++  NCN  ++ GK +    +  ++G+++   ++   L L +Q+MR  T+ +LE + GGG+K++D  I++WVN TL++A K+S I SFKD  I+TSLPV+DL+DAI+PGS+ Y L+ ++ L D      A YA+SMARKIGA  + LP+ +  +N KM+MT+FA LM  G++
Sbjct:  402 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRV--NKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDI-GGGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMK 625

[Close]

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V  N     +L    ++  NCN  ++ GK +    +  ++G+++   ++   L L +Q+MR  T+ +LE + GGG+K++D  I++WVN TL++A K+S I SFKD  I+TSLPV+DL+DAI+PGS+ Y L+ ++ L D      A YA+SMARKIGA  + LP+ +  +N KM+MT+FA LM  G++
Sbjct:  402 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRV--NKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDI-GGGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMK 625

[Close]

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V  N     +L    ++  NCN  ++ GK +    +  ++G+++   ++   L L +Q+MR  T+ +LE + GGG+K++D  I++WVN TL++A K+S I SFKD  I+TSLPV+DL+DAI+PGS+ Y L+ ++ L D      A YA+SMARKIGA  + LP+ +  +N KM+MT+FA LM  G++
Sbjct:  402 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRV--NKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDI-GGGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMK 625

[Close]

BLAST of Plastin-2 vs. Ensembl Mouse
Match: Pls3 (plastin 3 (T-isoform) [Source:MGI Symbol;Acc:MGI:104807])

HSP 1 Score: 149.058 bits (375), Expect = 2.880e-41
Identity = 89/226 (39.38%), Postives = 136/226 (60.18%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + +    L + +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  405 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGEGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 628

[Close]

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + +    L + +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  405 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKNPAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGEGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 628

[Close]

BLAST of Plastin-2 vs. UniProt/SwissProt
Match: sp|P54680|FIMB_DICDI (Fimbrin OS=Dictyostelium discoideum OX=44689 GN=fimA PE=2 SV=2)

HSP 1 Score: 154.066 bits (388), Expect = 2.430e-42
Identity = 89/220 (40.45%), Postives = 135/220 (61.36%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQG---NCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASL 636
            NW+NS G+   VN  Y  T DGL+ + +FDK+ PG V+  KV  N+   + +  E     NCN  I+ GK C   +  + G+N+ +++K   L + +Q+MR + I +L  L G GK I D DI++W N  L  AGK  +I+ FKD  I+T +P++D+++A++PGSV  +L+++     D L +A  AVS ARK+GA  F LP+ I  +  KM++TLFASL
Sbjct:  387 NWMNSLGVDPFVNNLYEGTYDGLILIQLFDKIYPGLVDHKKV--NYPPYKAMGAEMKKIENCNYAIQLGKDCKYSLVGIDGKNVYDKNKTLTLSILWQLMRGHVISILTALSGSGKPIADADIVNWTNSKLSAAGK-KQISGFKDSTISTGIPILDVIEAVRPGSVDPALVATSGSAEDNLLNAKLAVSTARKVGAVVFALPEDIVEVKPKMVLTLFASL 603

[Close]

BLAST of Plastin-2 vs. UniProt/SwissProt
Match: sp|Q61233|PLSL_MOUSE (Plastin-2 OS=Mus musculus OX=10090 GN=Lcp1 PE=1 SV=4)

HSP 1 Score: 152.91 bits (385), Expect = 8.586e-42
Identity = 92/228 (40.35%), Postives = 147/228 (64.47%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D +D LV   +++K+    V+W++V  N     +L    ++  NCN  ++ GK +    +  ++G+++   ++   L L +Q+MR  T+ +LE + GGG+K++D  I++WVN TL++A K+S I SFKD  I+TSLPV+DL+DAI+PGS+ Y L+ ++ L D      A YA+SMARKIGA  + LP+ +  +N KM+MT+FA LM  G++
Sbjct:  402 NWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKV-PVDWNRV--NKPPYPKLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDI-GGGQKVNDDIIVNWVNTTLKEAQKSSSIASFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDDEEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMK 625

[Close]

BLAST of Plastin-2 vs. UniProt/SwissProt
Match: sp|A7E3Q8|PLST_BOVIN (Plastin-3 OS=Bos taurus OX=9913 GN=PLS3 PE=2 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 1.552e-41
Identity = 91/226 (40.27%), Postives = 137/226 (60.62%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + ++   L L +Q+MR  T+ VLE L  G K  DD  + SWVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  405 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIV-SWVNRTLNEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGTLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 628

[Close]

BLAST of Plastin-2 vs. UniProt/SwissProt
Match: sp|Q6P698|PLSL_DANRE (Plastin-2 OS=Danio rerio OX=7955 GN=lcp1 PE=2 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 3.212e-41
Identity = 88/225 (39.11%), Postives = 139/225 (61.78%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGL 651
            NW+NS G+  +VN  Y D  D LV   +++K+    V+W KV +  +       ++  NCN  +E GKK     +  ++G+++   ++   L L +Q+MR  T+ +LE L  G K ID+  +  WVN+TL +AGK + I+ FKD +I++S+PV+DL+DAI+PGS++Y L+ ++ L D      A YA+SMARKIGA  + LP+ +  +  KM+MT+FA LM  G+
Sbjct:  400 NWMNSLGVNPRVNHLYVDLADALVIFQLYEKIKV-PVDWDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLGDGQKIIDETIV-QWVNETLTQAGKGT-ISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLKAEDLTDEKKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARGM 621

[Close]

BLAST of Plastin-2 vs. UniProt/SwissProt
Match: sp|P13797|PLST_HUMAN (Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4)

HSP 1 Score: 150.984 bits (380), Expect = 4.714e-41
Identity = 90/226 (39.82%), Postives = 137/226 (60.62%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+WSKV +    K     ++  NCN  +E GK      +  + G+++ + ++   L L +Q+MR  T+ VLE L  G K  DD  + +WVN TL +AGK++ I SFKD+ I++SL V+DL+DAI+PG + Y L+ S      D+  +A YAVSMAR+IGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  405 NWMNSLGVNPHVNHLYADLQDALVILQLYERIKV-PVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIV-NWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 628

[Close]

BLAST of Plastin-2 vs. TrEMBL
Match: T1G4W6 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20216114 PE=4 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 3.794e-53
Identity = 96/226 (42.48%), Postives = 144/226 (63.72%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXX-XXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI-----SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLENK 660
            NW+NS G+   V  FY D +DGL+ L +FD +   CVNW KVV+ F S R + ++ GNCN  +E GK+C   +  +SG+NI + DK ++L L +QMMR  T+ +L  +    +    DK+I++W N+ L++AGK+  IT F D+N+ T   VIDLVDAI PGS+ YS +       ++L++A Y + +AR+ GA  + LP+ I  +  KM+MT+FA LMI+ LE +
Sbjct:  395 NWMNSLGVNPFVYHFYSDLSDGLILLQLFDIIKHECVNWDKVVKEFKSNRAMMEKIGNCNYAVELGKECKFTLVGISGKNIHDGDKTHVLALVWQMMRVYTLSILSHIKQSKEGANIDKEIVAWANEKLKEAGKSRSITGFNDKNLTTGKAVIDLVDAISPGSINYSHVKDADTDEEKLENAKYGICVARRNGARIYALPEDIVEVKPKMVMTIFACLMILDLEKR 620

[Close]

BLAST of Plastin-2 vs. TrEMBL
Match: A0A3S4ZW02 (Uncharacterized protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS14695 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 7.281e-53
Identity = 96/215 (44.65%), Postives = 140/215 (65.12%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIV 645
            NW+NS G+   V     D   GL+FL + D L+   V+WSK+VR FD KRR+FQ Q NC+  IE      L + N SGE+IR  D+   LGL FQ+MR  TIK+L +L G G  ++D+D+++W N+ L   G  S + SF+D +I+T +PV++L++AIKP SV  S++S  +  +   A+S ARKIGA  + LP+H+  +N KM+MT+FA LM++
Sbjct:  215 NWMNSMGVAPFVKDLSVDLRTGLIFLQLVDILHTSTVDWSKIVRQFDPKRRIFQMQDNCSYAIEYANMLGLNVVNQSGEDIRTGDRKLTLGLAFQLMRAYTIKMLSRLQGNGYPVEDRDVLTWANERLASVG-ASALVSFRDSSISTGVPVLNLINAIKPNSVDKSMVSKAKEANCRLAISTARKIGARVYALPEHLRDVNPKMVMTVFACLMVL 428

[Close]

BLAST of Plastin-2 vs. TrEMBL
Match: A0A226E7T8 (Plastin-3 OS=Folsomia candida OX=158441 GN=Fcan01_12672 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 1.784e-51
Identity = 95/218 (43.58%), Postives = 135/218 (61.93%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  DGLV   ++D + PG V+W KV + F   R+  ++  NCN  +E GK+    +  ++G++I + +    L L +Q+MR  T+ VL +L   G  I +  II W N  LE AGKTSRI +F+D +I  S+ ++DL+DAIKPG + Y L+S+     D + +A YAVSMARK+GA  + LP+ IA L  KM+MTLFA LM
Sbjct:  401 NWMNSLGVSPHVNWLYSDLADGLVIFQLYDVIKPGIVDWKKVHKKFSKLRKFMEKLENCNYAVELGKQLKFSLVGIAGQDISDCNPTLTLALIWQLMRAYTLSVLSQLASSGDPIVESAIIDWANAKLESAGKTSRIKNFQDSSIRQSIVILDLIDAIKPGIINYELVSTEGTEEDNMANAKYAVSMARKVGARVYALPEDIAELKSKMVMTLFACLM 618

[Close]

BLAST of Plastin-2 vs. TrEMBL
Match: A0A411G7M8 (Putative plastin-2 isoform X2 (Fragment) OS=Cotesia chilonis OX=89804 PE=2 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 2.179e-51
Identity = 97/218 (44.50%), Postives = 134/218 (61.47%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  DGLV   ++D + PG VNW KV   F   R+  ++  NCN  ++ GKK N  +  ++G++I + +    L L +Q+MR  T+ VL  L G   K  +K+I+ WVN  L+ AGKTS I SF+D  I+T  PVIDL+DAIKPG V Y L+ +     D L +A YA+S+ARK GA  + LP+ I  + QKM+MT+FA LM
Sbjct:  412 NWMNSMGVSPHVNWLYSDLADGLVIFQLYDIIKPGTVNWPKVHTKFSKLRKFMEKLENCNYAVDLGKKMNFSLVGIAGQDINDGNATLTLALIWQLMRSYTLSVLSGLVGNSGKTVEKEIVQWVNSKLQAAGKTSSIKSFQDDAISTGRPVIDLIDAIKPGIVNYDLVKTSETEEDNLDNAKYAISLARKCGARVYALPEDITEVKQKMVMTVFACLM 629

[Close]

BLAST of Plastin-2 vs. TrEMBL
Match: A0A1W0X7Q4 (Plastin-1 OS=Hypsibius dujardini OX=232323 GN=BV898_02676 PE=4 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 3.371e-51
Identity = 96/218 (44.04%), Postives = 139/218 (63.76%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D T G++   ++D + PG VNW KVV+NF   R   ++  NCN  +E G++ N  +  ++G++I + +    L L +Q+MR  T+ +L KL   G  I +K+IISWVN  L  AGKTS ITSF+D+ I+ +  VIDL+DAIKPG + YS   +     +++ +A YA+SMARKIGA  + LP+ I  + QKM+MT+FA LM
Sbjct:  399 NWMNSMGVNPYVNYLYGDLTTGVIIFQLYDIIKPGIVNWKKVVKNFHKMRGFMEKVENCNYAVELGRQLNFSLVGIAGQDISDGNPTLTLALVWQLMRAYTLSILTKLARSGNPIVEKEIISWVNKKLSSAGKTSSITSFQDQTISDAAVVIDLIDAIKPGCINYSQTQAAKTTDEKVANAKYAISMARKIGARIYALPEDIVEVKQKMVMTVFACLM 616

[Close]

BLAST of Plastin-2 vs. Ensembl Cavefish
Match: pls3 (plastin 3 (T isoform) [Source:ZFIN;Acc:ZDB-GENE-040718-10])

HSP 1 Score: 155.992 bits (393), Expect = 3.076e-44
Identity = 93/228 (40.79%), Postives = 141/228 (61.84%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++++    V+W+  V N     +L    ++  NCN  ++ GK      +  + G+++ + +    L L +Q+MR  T+ VLE L  G K  DD  + +WVN TL  AGK+++I+SFKD+ I++SLPV+DL+DAI+PGSV Y L+ +      D+L++A YAVSMARKIGA  + LPD +  +  KM+MT+FA LM  G++
Sbjct:  337 NWMNSLGVNPHVNHLYGDLQDALVILQLYERIKV-PVDWNNKV-NKPPYPKLGANMKKLENCNYAVDLGKTTAKFSLVGIGGQDLNDGNPTLTLALVWQLMRRYTLNVLEDLGDGEKVNDDIIV-NWVNKTLAGAGKSTKISSFKDKEISSSLPVLDLIDAIQPGSVHYDLVKTGSLSDQDKLENAKYAVSMARKIGARVYALPDDLVEVKPKMVMTVFACLMGRGMK 561

[Close]

BLAST of Plastin-2 vs. Ensembl Cavefish
Match: pls1 (plastin 1 (I isoform) [Source:ZFIN;Acc:ZDB-GENE-030131-6205])

HSP 1 Score: 152.525 bits (384), Expect = 1.022e-42
Identity = 88/221 (39.82%), Postives = 132/221 (59.73%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLM 639
            NW+NS G+   VN  Y D  DGL+ L +++++    V+W KV R  +       ++  NCN  +E GK+     +  + GENI     ++ L L +Q+MR  T+KVL  +  G K  D   +  WVN TL+K  K S I +FKD++I+TSLPVIDL+D I PG+++  ++        D+L +A YA+S++RKIGA  + LPD +  +N KM+MT+FA LM
Sbjct:  383 NWMNSLGVNPYVNHLYSDLMDGLIILQLYERIQV-PVDWRKVNRPPYSILGSNMKKLENCNYAVELGKREAKFSLVGIGGENINEGSAMHTLALVWQLMRRYTVKVLADIGHGEKVNDQIIV-DWVNSTLQKGQKDSSIKNFKDKSISTSLPVIDLIDTIAPGAIKSEMVKRGDMSPEDKLNNAKYAISVSRKIGAKVYALPDDLVEVNPKMVMTVFACLM 601

[Close]

BLAST of Plastin-2 vs. Ensembl Cavefish
Match: lcp1 (lymphocyte cytosolic protein 1 (L-plastin) [Source:NCBI gene;Acc:30583])

HSP 1 Score: 151.369 bits (381), Expect = 3.269e-42
Identity = 89/226 (39.38%), Postives = 139/226 (61.50%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D  D L+   +++K+    V+W KV +  +       ++  NCN  +E GKK     +  ++G+++   ++   L L +Q+MR  T+ +LE L  G K  DD  +  WVNDTL++A K + I+ FKD +I++S+PV+DL+DAI+PGS++Y LI ++ L D      A YA+SMARKIGA  + LP+ +  +  KM+MT+FA LM  GL+
Sbjct:  398 NWMNSLGVNPRVNHLYGDLADALIIFQLYEKIKV-PVDWDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLGDGQKVNDDTIV-GWVNDTLKQADKKT-ISGFKDGSISSSMPVLDLIDAIQPGSIRYDLIKAEDLSDEEKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARGLK 620

[Close]

BLAST of Plastin-2 vs. Ensembl Sea Lamprey
Match: lcp1 (lymphocyte cytosolic protein 1 (L-plastin) [Source:NCBI gene;Acc:30583])

HSP 1 Score: 153.68 bits (387), Expect = 9.556e-46
Identity = 92/225 (40.89%), Postives = 132/225 (58.67%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL-FQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS------DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV + +F+K+    V+W+KV +    K     ++  NCN  +E GK     +  + G+++ + +    L L +Q+MR  TI+VLE L  G K  D+  + +WVN TL  AGK+S I SFK    A S P  DL+DAI+PGS++Y L+        DRL +A YA+SMARKIGA  + LPD +  +  KM+MT+FA LM  G++
Sbjct:  111 NWMNSLGVNPFVNHLYSDLVDALVIIQLFEKIK-TRVDWNKVNKPPYPKLGANMKKLENCNYAVELGKTTKFSLVGIGGQDLNDGNPTLTLALVWQLMRKYTIQVLEDLGEGEKVNDEIIV-NWVNHTLRDAGKSSSIASFKVPPTALSTPCWDLIDAIQPGSIRYDLVKEEPLTDDDRLDNAKYAISMARKIGARVYALPDDLVEVKPKMVMTMFACLMGRGMK 333

[Close]

BLAST of Plastin-2 vs. Ensembl Yeast
Match: SAC6 (Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536])

HSP 1 Score: 117.087 bits (292), Expect = 7.590e-31
Identity = 68/221 (30.77%), Postives = 123/221 (55.66%), Query Frame = 1

Query:    4 WINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRL--FQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLIS-----SDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIV 645
            W+NS  +   V + + D  DGL+ L  ++K+ PG V++  V +   S   +  F+   N N  ++ G+     +  + G +I + +K+  LGL +Q+MR N    ++ L   G+ + D  I+ W  D + K GK S I SFKD+ ++ +  ++D+++ I PG V Y L++      +R  +A  A+S+ARK+GA  +++P+ I  +  ++I+T  ASLM +
Sbjct:  420 WLNSLDVDPPVISLFDDLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARKLGALIWLVPEDINEVRARLIITFIASLMTL 640

[Close]

BLAST of Plastin-2 vs. Ensembl Nematostella
Match: EDO32484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUX1])

HSP 1 Score: 159.073 bits (401), Expect = 1.195e-45
Identity = 90/226 (39.82%), Postives = 132/226 (58.41%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLENK 660
            NWINS GI   V   Y D  DG++   +FD++ PG VN+ KV +  F       ++  NCN  I         +  + G++I + +K+ IL L +Q MR  T+ VL+K  G  K + + +I+ WVN+ L  AGK + IT  KD  I TS  V+DL+DAIKP ++ YS++++     D   +A YA+SMARK+GA  + LP+ +     KM+MT+FA LM  GL+NK
Sbjct:  370 NWINSLGIKPFVQNLYLDLDDGMILFQLFDQVQPGIVNYDKVNKPPFKKMGAKMKKLENCNYAISVADLLKFSLVGVGGKDINDGNKMLILALLWQTMRAYTLTVLQKCAGSEKPVTEAEIVVWVNEKLSSAGKATTITGMKDPEIKTSKCVLDLIDAIKPKAINYSMVNAGECQEDAFLNAKYAISMARKVGARVYALPEDLVEGKSKMVMTVFACLMARGLKNK 595

[Close]

BLAST of Plastin-2 vs. Ensembl Nematostella
Match: EDO40382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7E1])

HSP 1 Score: 154.066 bits (388), Expect = 1.516e-43
Identity = 91/233 (39.06%), Postives = 132/233 (56.65%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQG------NCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRIT---SFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NWINS G    VN  Y D  DG++   +F+ + PGCV+W K V N + K +  +  G      NCN  ++ GK+ N  +  + G++I    +   LGL +QMMR  T  +L +L      + ++ I+ WVN TL+   KT  I     FKD +I+TSL V+DL+D I P  +  +LI+ D L D      A YA+SMARKIGA  + LP+ +  +  KM++T+FASLM+  LE
Sbjct:  415 NWINSMGCGRYVNWLYSDFFDGIILFKMFEHIRPGCVDWEKKV-NPEGKCKNARMGGKVKCIENCNYAVDLGKQFNFSLIGIQGQDIHEGVQNLTLGLIWQMMRAYTYTLLARLSPDDDHMTEEKIVEWVNKTLQSKKKTHLINKGHGFKDPDISTSLAVLDLIDCISPKMINPALINPDPLSDEDKLPNAQYAISMARKIGAVVYALPEDLVEVKPKMVLTVFASLMLCALE 646

[Close]

BLAST of Plastin-2 vs. Ensembl Nematostella
Match: EDO32486 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUX4])

HSP 1 Score: 101.679 bits (252), Expect = 6.069e-28
Identity = 50/103 (48.54%), Postives = 68/103 (66.02%), Query Frame = 1

Query:  367 WVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISS-----DRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLENK 660
            WVN+ L  AGK + IT  KD  I TS  V+DL+DAIKP ++ YS++++     D   +A YA+SMARK+GA  + LP+ +     KM+MT+FA LM  GLENK
Sbjct:    4 WVNEKLSSAGKATTITGMKDPEIKTSKCVLDLIDAIKPKAINYSMVNAGECQEDAFLNAKYAISMARKVGARVYALPEDLVEGKSKMVMTVFACLMARGLENK 106

[Close]

BLAST of Plastin-2 vs. Ensembl Nematostella
Match: EDO27717 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8H0])

HSP 1 Score: 81.6481 bits (200), Expect = 2.449e-20
Identity = 41/85 (48.24%), Postives = 57/85 (67.06%), Query Frame = 1

Query:  418 FKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKD------ASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            FKD +I+TSL V+DL+D I P  +  +LI+ D L D      A YA+SMARKIGA  + LP+ +  +  KM++T+FASLM+  LE
Sbjct:    1 FKDPDISTSLAVLDLIDCISPKMINPALINPDPLSDEDKLPNAQYAISMARKIGAVVYALPEDLVEVKPKMVLTVFASLMLCALE 85

[Close]

BLAST of Plastin-2 vs. Ensembl Medaka
Match: pls3 (plastin-3 [Source:NCBI gene;Acc:101161915])

HSP 1 Score: 151.369 bits (381), Expect = 2.907e-42
Identity = 91/228 (39.91%), Postives = 139/228 (60.96%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLN-PGCVNWSKVVRNFDSKRRL---FQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   VN  Y D  D LV L +++K+  P  V+W+  V N     +L    ++  NCN  +E G+     +  + G+++ + +    L + +Q+MR  T+ VLE L  G K  DD  +  WVN TL  A K+++I+SFKD+ I+TSL V++L+DAI+PGSV Y LI       +D+L++A YA+SMARKIGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  397 NWMNSLGVNPHVNHLYGDLQDALVILQLYEKIKIP--VDWNNKV-NKPPYPKLGTNMKKLENCNYAVELGRSAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVLEDLGDGDKVNDDIIV-KWVNKTLADAEKSTKISSFKDKEISTSLSVLELIDAIQPGSVNYELIKTSSLSDADKLENAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMGRGMK 620

[Close]

BLAST of Plastin-2 vs. Ensembl Medaka
Match: pls1 (plastin-1 [Source:NCBI gene;Acc:101168586])

HSP 1 Score: 151.369 bits (381), Expect = 3.600e-42
Identity = 91/227 (40.09%), Postives = 134/227 (59.03%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI---------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVG 648
            NW+NS G+   VN  Y+D  DGLV L + +K+    VNW KV    F       ++  NCN  ++ GK   +  +  + GEN+    +V+ L L +Q+MR  T+ VL  L  G K  D   + +WVN TL +  K S+I++FKD+ I+TS+PV DL+D I PG+V++ ++         + D+L +A YA+S+ARKIGA  + LPD +  +N KM+MTLFA LM  G
Sbjct:  403 NWMNSLGVSPSVNHLYWDLCDGLVILQLMEKVKV-PVNWKKVNNPPFSMLGGNMKKLENCNYAVQLGKNVAHFSLVGVGGENLNEGSRVHTLALVWQLMRRYTVMVLSDLGDGEKIGDQIIL-NWVNTTLGQKKKASQISNFKDKLISTSMPVFDLIDCIVPGAVKWDMVKKDARGKMSNEDKLDNAKYAISLARKIGARVYALPDDLVEVNPKMVMTLFACLMGYG 627

[Close]

BLAST of Plastin-2 vs. Ensembl Medaka
Match: pls1 (plastin-1 [Source:NCBI gene;Acc:101168586])

HSP 1 Score: 151.369 bits (381), Expect = 4.639e-42
Identity = 94/227 (41.41%), Postives = 139/227 (61.23%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGKK-CNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI---------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVG 648
            NW+NS G+   VN  Y+D  DGLV L + +K+    VNW KV    F       ++  NCN  ++ GK   +  +  + GEN+    +V+ L L +Q+MR  T+ VL  L G G+KI D+ I++WVN TL +  K S+I++FKD+ I+TS+PV DL+D I PG+V++ ++         + D+L +A YA+S+ARKIGA  + LPD +  +N KM+MTLFA LM  G
Sbjct:  440 NWMNSLGVSPSVNHLYWDLCDGLVILQLMEKVKV-PVNWKKVNNPPFSMLGGNMKKLENCNYAVQLGKNVAHFSLVGVGGENLNEGSRVHTLALVWQLMRRYTVMVLSDL-GDGEKIGDQIILNWVNTTLGQKKKASQISNFKDKLISTSMPVFDLIDCIVPGAVKWDMVKKDARGKMSNEDKLDNAKYAISLARKIGARVYALPDDLVEVNPKMVMTLFACLMGYG 664

[Close]

BLAST of Plastin-2 vs. Ensembl Medaka
Match: ENSORLT00000011106.2 (plastin-3-like [Source:NCBI gene;Acc:101157305])

HSP 1 Score: 150.984 bits (380), Expect = 4.834e-42
Identity = 91/228 (39.91%), Postives = 140/228 (61.40%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKR---RLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLI------SSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   V+  Y D  D +V L +++K+    V+W+  V +   K       ++  NCN  +E GK K    +  + G+++ + +++  L L +Q+MR  T+ +LE L  G    DD  I SWVN TL +A K+S I SFKD++I+TSLPV+DL+DAI+P SV + L+      ++D+L +A YAVSMARKIGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  393 NWMNSLGVTPHVHYIYGDLQDAMVILQLYEKIKVK-VDWNNRVNHPPFKGVGGGHLKKIENCNYAVELGKQKAGFSLVGIGGQDLYDGNEMLTLALMWQLMRRYTLNLLEDLGHGEVAGDDLII-SWVNKTLAEADKSSSIKSFKDKSISTSLPVLDLIDAIQPESVNFELVKRDAESNADKLDNAKYAVSMARKIGAKVYALPEDLVEVKPKMVMTIFACLMGRGMK 618

[Close]

BLAST of Plastin-2 vs. Ensembl Medaka
Match: lcp1 (plastin-2 [Source:NCBI gene;Acc:101162720])

HSP 1 Score: 150.599 bits (379), Expect = 5.249e-42
Identity = 88/226 (38.94%), Postives = 140/226 (61.95%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRN-FDSKRRLFQEQGNCNEVIEAGK-KCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSD------RLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+  +VN  Y D  D LV   +++K+    VNW +V +  +       ++  NCN  +E GK +    +  ++G+++   ++   L L +Q+MR  T+ +LE L  G K  DD  + SWVNDTL  A K + I+SFKD +I++S+PV+DL+DAI+PGS++Y L+ ++      +L +A YA+SMARKIGA  + LP+ +  +  KM+MT+FA LM  G++
Sbjct:  395 NWMNSLGVNPRVNHLYADIDDALVIFQLYEKIKVP-VNWDRVNKPPYPKLGSNMKKLENCNYAVELGKNEAKFSLVGIAGQDLNAGNRTLTLALLWQLMRRYTLNILEDLGDGQKVTDDTIV-SWVNDTLTHAEKNT-ISSFKDMSISSSMPVLDLIDAIQPGSIRYDLVKAEDLTEEEKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARGMK 617

[Close]

BLAST of Plastin-2 vs. Planmine SMEST
Match: SMESG000007726.1 (SMESG000007726.1)

HSP 1 Score: 425.631 bits (1093), Expect = 5.051e-148
Identity = 219/220 (99.55%), Postives = 220/220 (100.00%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLENK 660
            NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCGGGKKIDDKDIISWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAF+LPDHIASLNQKMIMTLFASLMIVGLENK
Sbjct:  395 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCGGGKKIDDKDIISWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFVLPDHIASLNQKMIMTLFASLMIVGLENK 614

[Close]

BLAST of Plastin-2 vs. Planmine SMEST
Match: SMESG000070679.1 (SMESG000070679.1)

HSP 1 Score: 196.052 bits (497), Expect = 1.374e-59
Identity = 103/221 (46.61%), Postives = 145/221 (65.61%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXX--XXXXXXXXXSWVNDTLEKAGKT-SRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   +N  Y D  +G+  L++ D + P  VNW  V   F+  R+LFQ Q NC   I   KK NLK+  +S ENIR  +   +LGLCFQ++R  T ++L+KL      K ++DKDII W N   +  GK+ S I SFKD NI +S P++ L+D+IKP SV YS+I+++ L DA YA+++ARKIGAN + LP H+  LNQKMI+T++A LM+V L+
Sbjct:  318 NWMNSMGVEPYLNYLYSDLRNGIALLHLIDVIQPKTVNWETVTTKFNPMRKLFQMQDNCLAFINYAKKLNLKLVGLSAENIRETETTLVLGLCFQLLRKYTFQLLQKLQPNNFNKSVEDKDIIEWANKKCQSTGKSESVIRSFKDLNIRSSKPILHLIDSIKPNSVDYSMITNNPLDDAKYAITVARKIGANVYALPQHVVDLNQKMILTIYACLMLVDLQ 538

[Close]

BLAST of Plastin-2 vs. Planmine SMEST
Match: SMESG000081113.1 (SMESG000081113.1)

HSP 1 Score: 194.126 bits (492), Expect = 3.007e-58
Identity = 106/215 (49.30%), Postives = 147/215 (68.37%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIV 645
            NW+NS G+   V   Y D  +GLV L + D L PG V W K+VR FD K+++FQ  GNC+ VIE  KK N  I N+S +NI++     +LGLCFQM+R  T+K+L K+     K DDKDII W N   E A KTS+I+SFKD +IATS P++DL+DAI P SV + L++++ L+DA + +S AR+IGA  + LP H+  +NQKM+MT++A LM++
Sbjct:  401 NWMNSMGVTPYVKDIYSDLKNGLVLLQLIDLLQPGIVEWKKIVRVFDPKKKVFQILGNCSYVIEYAKKLNFNIVNLSADNIKDATPNMVLGLCFQMLRSYTMKLLSKVL--PGKKDDKDIIGWANKKTEAANKTSKISSFKDPSIATSKPILDLIDAIVPNSVDFKLLTNEPLQDAKFTISQARRIGARIYALPQHLVDVNQKMVMTVYACLMLL 613

HSP 2 Score: 50.0618 bits (118), Expect = 5.242e-7
Identity = 52/215 (24.19%), Postives = 95/215 (44.19%), Query Frame = 1

Query:   37 NTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVL---------------EKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFK----DRNIATSL-----PVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQK 609
            +  Y    DG++   + +   P  V+  +V+    S + +F++  N    + + +     + N+  E+I    K  ILGL +Q++R   + ++               E L    +   ++ ++ WVN  LEKAG T RIT+FK    D  I + L     P     + + P S+   L ++D +K A   +  A  + A  FI P+ +A + Q+
Sbjct:  149 DELYNKLQDGVLLCKLINSAVPDTVD-ERVMNTGASLKSVFKKNENLCLAVNSAEAIGCCMVNIGPEDIDKGTKHLILGLVWQVIRIGLLGLVNLLHHAELVALLREDETLDDLKQLTPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPADKRDEMLPPISI---LKNTDNMKRAELMLGNASILDARVFIEPEDVAMVTQR 359

[Close]

BLAST of Plastin-2 vs. Planmine SMEST
Match: SMESG000081126.1 (SMESG000081126.1)

HSP 1 Score: 188.734 bits (478), Expect = 3.847e-56
Identity = 102/218 (46.79%), Postives = 148/218 (67.89%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMIVGLE 654
            NW+NS G+   V   Y D  +GLV L + D L PG V WSK+++ FD K+++FQ  GNC+ VIE  KK N  I N+S +NI++     +LGLCFQM+R+ T+ +L  +     K DDKDII W N   E+A K S+I+SFKD +IATS P++DL+DAI P SV + L++++ L+DA + +S AR+IGA  + LP H+  +NQKM+MT++A LM++  +
Sbjct:  398 NWMNSMGVTPYVKDIYSDLKNGLVLLQLIDLLQPGIVEWSKIIKVFDPKKKVFQILGNCSYVIEYAKKLNFNIVNLSADNIKDATPNMVLGLCFQMLRFYTMTLLSSVL--RDKKDDKDIIIWANLKTEQANKYSQISSFKDPSIATSKPILDLIDAIVPNSVDFKLLTNEPLQDAKFTISQARRIGARIYALPQHLVDVNQKMVMTVYACLMMLDFD 613

HSP 2 Score: 50.8322 bits (120), Expect = 2.817e-7
Identity = 52/215 (24.19%), Postives = 95/215 (44.19%), Query Frame = 1

Query:   37 NTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIKVL---------------EKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFK----DRNIATSL-----PVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQK 609
            +  Y    DG++   + +   P  V+  +V+    S + +F++  N    + + +     + N+  E+I    K  ILGL +Q++R   + ++               E L    +   ++ ++ WVN  LEKAG T RIT+FK    D  I + L     P     + + P S+   L ++D +K A   +  A  + A  FI P+ +A + Q+
Sbjct:  146 DELYNKLQDGVLLCKLINSAVPDTVD-ERVMNTGASLKSVFKKNENLCLAVNSAEAIGCCMVNIGPEDIDKGTKHLILGLVWQVIRIGLLGLVNLLHHAELVALLREDETLDDLKQLTPEELLLRWVNYHLEKAGITKRITNFKEDIQDSEIYSHLLYQIAPADKRDEMLPPISI---LKNTDNMKRAELMLGNASILDARVFIEPEDVAMVTQR 356

[Close]

BLAST of Plastin-2 vs. Planmine SMEST
Match: SMESG000048251.1 (SMESG000048251.1)

HSP 1 Score: 105.531 bits (262), Expect = 4.182e-26
Identity = 68/216 (31.48%), Postives = 108/216 (50.00%), Query Frame = 1

Query:    1 NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKRRLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYNTIK--VLEKLCXXXXXXXXXXXXSWVNDTLEKAGKTSRITSFKDRNIATSLPVIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASLNQKMIMTLFASLMI 642
            N++NS  +    N    D  +G +   +F+ L PG  +  K + +FDS R   Q   NC ++++  +   L   N+  E I + DK  ILGL  +MMR    +   +EK           +I+ W N  L K+GK S + SF DR IA       +++++ PG V  S + +++L +A Y VS+A K G   + LP+H    N K +   FA+LM+
Sbjct:  305 NFLNSFDVYPFCNHVLNDCRNGWILGELFEVLRPGYTSGVKFILDFDSNRIHAQRVHNCTKIVKLAQNYVLNTPNLDAEKIADSDKSSILGLIVEMMRAYVCRDNYIEK-----------EILDWANCQLRKSGKQSMMRSFGDRIIAEDNLFAVVLESVAPGLVDRSCLGNNKLLNAYYYVSIAHKAGIPVYTLPEHFVEGNAKFVALAFATLMV 509

The following BLAST results are available for this feature:

BLAST of Plastin-2 vs. Ensembl Human
BLAST of Plastin-2 vs. Ensembl Celegans
BLAST of Plastin-2 vs. Ensembl Fly
BLAST of Plastin-2 vs. Ensembl Zebrafish
BLAST of Plastin-2 vs. Ensembl Xenopus
BLAST of Plastin-2 vs. Ensembl Mouse
BLAST of Plastin-2 vs. UniProt/SwissProt
BLAST of Plastin-2 vs. TrEMBL
BLAST of Plastin-2 vs. Ensembl Cavefish
BLAST of Plastin-2 vs. Ensembl Sea Lamprey
BLAST of Plastin-2 vs. Ensembl Yeast
BLAST of Plastin-2 vs. Ensembl Nematostella
BLAST of Plastin-2 vs. Ensembl Medaka
BLAST of Plastin-2 vs. Planmine SMEST

BLAST of Plastin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PLS3	9.817e-42	39.82	plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]	[more]
PLS3	9.817e-42	39.82	plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]	[more]
PLS3	9.924e-42	39.82	plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]	[more]
PLS3	1.013e-41	39.82	plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]	[more]
PLS1	2.954e-39	39.11	plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090]	[more]

BLAST of Plastin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
plst-1	3.059e-45	37.44	PLaSTin (Actin bundling protein) homolog [Source:...	[more]
plst-1	3.481e-45	37.90	PLaSTin (Actin bundling protein) homolog [Source:...	[more]
Y73B3B.1	9.300e-24	30.60	pep chromosome:WBcel235:X:209108:211241:-1 gene:WB...	[more]

BLAST of Plastin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Fim	5.507e-51	40.83	gene:FBgn0024238 transcript:FBtr0074442	[more]
Fim	6.700e-51	40.83	gene:FBgn0024238 transcript:FBtr0074443	[more]
Fim	7.263e-51	40.83	gene:FBgn0024238 transcript:FBtr0074441	[more]

BLAST of Plastin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pls3	4.217e-43	40.79	plastin 3 (T isoform) [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pls3	4.217e-43	40.79	plastin 3 (T isoform) [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pls1	3.091e-42	40.09	plastin 1 (I isoform) [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
pls1	4.272e-42	40.09	plastin 1 (I isoform) [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
lcp1	4.521e-42	39.11	lymphocyte cytosolic protein 1 (L-plastin) [Source...	[more]

BLAST of Plastin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snx5	3.815e-43	39.82	sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018...	[more]
snx5	3.928e-43	39.82	sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018...	[more]
snx5	7.246e-43	39.82	sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018...	[more]
snx5	9.848e-43	39.82	sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018...	[more]
snx5	9.971e-43	39.82	sorting nexin 5 [Source:Xenbase;Acc:XB-GENE-947018...	[more]

BLAST of Plastin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lcp1	1.228e-42	40.35	lymphocyte cytosolic protein 1 [Source:MGI Symbol;...	[more]
Lcp1	1.228e-42	40.35	lymphocyte cytosolic protein 1 [Source:MGI Symbol;...	[more]
Lcp1	1.228e-42	40.35	lymphocyte cytosolic protein 1 [Source:MGI Symbol;...	[more]
Pls3	2.880e-41	39.38	plastin 3 (T-isoform) [Source:MGI Symbol;Acc:MGI:1...	[more]
Pls3	2.880e-41	39.38	plastin 3 (T-isoform) [Source:MGI Symbol;Acc:MGI:1...	[more]

BLAST of Plastin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P54680\|FIMB_DICDI	2.430e-42	40.45	Fimbrin OS=Dictyostelium discoideum OX=44689 GN=fi...	[more]
sp\|Q61233\|PLSL_MOUSE	8.586e-42	40.35	Plastin-2 OS=Mus musculus OX=10090 GN=Lcp1 PE=1 SV...	[more]
sp\|A7E3Q8\|PLST_BOVIN	1.552e-41	40.27	Plastin-3 OS=Bos taurus OX=9913 GN=PLS3 PE=2 SV=1	[more]
sp\|Q6P698\|PLSL_DANRE	3.212e-41	39.11	Plastin-2 OS=Danio rerio OX=7955 GN=lcp1 PE=2 SV=1	[more]
sp\|P13797\|PLST_HUMAN	4.714e-41	39.82	Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=...	[more]

BLAST of Plastin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
T1G4W6	3.794e-53	42.48	Uncharacterized protein OS=Helobdella robusta OX=6...	[more]
A0A3S4ZW02	7.281e-53	44.65	Uncharacterized protein OS=Protopolystoma xenopodi...	[more]
A0A226E7T8	1.784e-51	43.58	Plastin-3 OS=Folsomia candida OX=158441 GN=Fcan01_...	[more]
A0A411G7M8	2.179e-51	44.50	Putative plastin-2 isoform X2 (Fragment) OS=Cotesi...	[more]
A0A1W0X7Q4	3.371e-51	44.04	Plastin-1 OS=Hypsibius dujardini OX=232323 GN=BV89...	[more]

BLAST of Plastin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
pls3	3.076e-44	40.79	plastin 3 (T isoform) [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pls1	1.022e-42	39.82	plastin 1 (I isoform) [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
lcp1	3.269e-42	39.38	lymphocyte cytosolic protein 1 (L-plastin) [Source...	[more]

BLAST of Plastin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
lcp1	9.556e-46	40.89	lymphocyte cytosolic protein 1 (L-plastin) [Source...	[more]

BLAST of Plastin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
SAC6	7.590e-31	30.77	Fimbrin, actin-bundling protein; cooperates with S...	[more]

BLAST of Plastin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO32484	1.195e-45	39.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40382	1.516e-43	39.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32486	6.069e-28	48.54	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27717	2.449e-20	48.24	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Plastin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pls3	2.907e-42	39.91	plastin-3 [Source:NCBI gene;Acc:101161915]	[more]
pls1	3.600e-42	40.09	plastin-1 [Source:NCBI gene;Acc:101168586]	[more]
pls1	4.639e-42	41.41	plastin-1 [Source:NCBI gene;Acc:101168586]	[more]
ENSORLT00000011106.2	4.834e-42	39.91	plastin-3-like [Source:NCBI gene;Acc:101157305]	[more]
lcp1	5.249e-42	38.94	plastin-2 [Source:NCBI gene;Acc:101162720]	[more]

BLAST of Plastin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000007726.1	5.051e-148	99.55	SMESG000007726.1	[more]
SMESG000070679.1	1.374e-59	46.61	SMESG000070679.1	[more]
SMESG000081113.1	3.007e-58	49.30	SMESG000081113.1	[more]
SMESG000081126.1	3.847e-56	46.79	SMESG000081126.1	[more]
SMESG000048251.1	4.182e-26	31.48	SMESG000048251.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30012493 ID=SMED30012493|Name=Plastin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=666bp
AATTGGATAAATTCTCAAGGTATTTTAACTCAGGTTAATACATTTTACTA
CGACACCACCGATGGTCTTGTTTTTCTGTATATATTTGACAAGTTGAATC
CGGGCTGTGTCAATTGGTCGAAAGTGGTTCGAAATTTTGATTCAAAAAGA
AGATTGTTTCAAGAACAAGGTAATTGCAACGAAGTAATTGAAGCTGGTAA
AAAATGCAATTTGAAAATTCAAAATATGTCCGGAGAAAATATCCGAAATC
GAGACAAAGTTTATATATTGGGACTTTGTTTCCAGATGATGAGATATAAT
ACTATAAAAGTTCTAGAAAAGTTGTGTGGAGGCGGAAAGAAAATCGACGA
TAAGGATATTATTTCTTGGGTAAATGATACTTTGGAAAAGGCAGGTAAAA
CTAGTCGGATAACCAGTTTTAAAGATCGGAATATTGCAACGTCACTGCCT
GTTATAGATTTGGTAGACGCAATCAAACCCGGATCAGTTCAGTATAGTTT
GATTTCGAGTGACCGTTTAAAAGATGCAAGTTATGCCGTTTCTATGGCTC
GTAAAATAGGAGCAAATGCTTTTATTTTACCGGACCATATTGCGAGTCTT
AATCAAAAAATGATAATGACTTTATTTGCTTCTTTGATGATTGTCGGATT
GGAAAATAAATGCTAT

protein sequence of SMED30012493-orf-1

>SMED30012493-orf-1 ID=SMED30012493-orf-1|Name=SMED30012493-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=222bp
NWINSQGILTQVNTFYYDTTDGLVFLYIFDKLNPGCVNWSKVVRNFDSKR
RLFQEQGNCNEVIEAGKKCNLKIQNMSGENIRNRDKVYILGLCFQMMRYN
TIKVLEKLCGGGKKIDDKDIISWVNDTLEKAGKTSRITSFKDRNIATSLP
VIDLVDAIKPGSVQYSLISSDRLKDASYAVSMARKIGANAFILPDHIASL
NQKMIMTLFASLMIVGLENKCY

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0051015	actin filament binding
GO:0005515	protein binding
GO:0003779	actin binding

Vocabulary: **biological process**
Term	Definition
GO:0051017	actin filament bundle assembly

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia

Vocabulary: **INTERPRO**
Term	Definition
IPR036872	CH_dom_sf
IPR039959	Fimbrin/Plastin
IPR001715	CH-domain

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001715	Calponin homology domain	SMART	SM00033	ch_5	coord: 1..99 e-value: 2.4E-4 score: 30.4 coord: 116..215 e-value: 2.5E-10 score: 50.3
IPR001715	Calponin homology domain	PFAM	PF00307	CH	coord: 117..213 e-value: 1.9E-13 score: 50.5 coord: 1..100 e-value: 1.4E-9 score: 38.1
IPR001715	Calponin homology domain	PROSITE	PS50021	CH	coord: 1..101 score: 14.799
IPR001715	Calponin homology domain	PROSITE	PS50021	CH	coord: 114..217 score: 15.125
IPR036872	CH domain superfamily	GENE3D	G3DSA:1.10.418.10		coord: 108..214 e-value: 2.2E-30 score: 106.9
IPR036872	CH domain superfamily	GENE3D	G3DSA:1.10.418.10		coord: 1..107 e-value: 1.2E-19 score: 72.4
IPR036872	CH domain superfamily	SUPERFAMILY	SSF47576	Calponin-homology domain, CH-domain	coord: 1..213
IPR039959	Fimbrin/Plastin	PANTHER	PTHR19961	FIMBRIN/PLASTIN	coord: 1..219
None	No IPR available	PANTHER	PTHR19961:SF18	FI19014P1	coord: 1..219