Importin subunit alpha

Overview
NameImportin subunit alpha
Smed IDSMED30012458
Length (bp)1623
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Importin subunit alpha (SMED30012458) t-SNE clustered cells

Violin plots show distribution of expression levels for Importin subunit alpha (SMED30012458) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Importin subunit alpha (SMED30012458) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Importin subunit alpha (SMED30012458) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30012458

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30012458SMESG000063514.1 SmedASXL_015843SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30012458SMESG000063514.1 SmedASXL_015843SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
cephalic gangliaSMED30012458SMESG000063514.1 dd_Smed_v4_3708_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30012458SMESG000063514.1 dd_Smed_v4_3708_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30012458SMESG000063514.1 dd_Smed_v6_3708_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
zeta neoblastSMED30012458SMESG000063514.1 dd_Smed_v4_3708_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30012458SMESG000063514.1 SMED_02149_V2_1GPL14150PMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30012458SMESG000063514.1 SMED_02149_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012
whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA2 (karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395])

HSP 1 Score: 335.88 bits (860), Expect = 1.417e-108
Identity = 177/483 (36.65%), Postives = 286/483 (59.21%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLE--VLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R + +KN  KD   +RR R + +VE+RKAKK+DQ+ KRRN V     D    +    N +   + ++++I K + S N+   L A  + RKLLS++K PPI++  + G IP  V  +       + FESAWALTNIASG ++ T+AVV  GAIP F+ L++     +SEQ++WAL NIAGD + +RD+++K+G +D +   + +   S L    LR++ W +SNLCR+K+   P   + ++LP L+R  ++  +D     D  WA+SY  D  ++ I  ++   +VP L+  L   E  IVTP+LRAIGN++ GTDEQ    I  G +     LL++    + KE+ W +SNI AG + QIQ  V+  ++  L+ V+   D+K+QKEA WAV+N  +    +  +YL++  +   ++ +L+  +  +++++LDA+  +F  A+K+G+ E      E+ GG+D IE+LQ HE+  +Y  S  ++
Sbjct:   13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRN-VSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVR--LLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLI 492          

HSP 2 Score: 61.2326 bits (147), Expect = 3.052e-9
Identity = 61/280 (21.79%), Postives = 124/280 (44.29%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIA-----GTDEQADAAIK-CGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACV 1148
            CR   +K   PPI+   +   +P LV+++  +  E+L  ++ WA++ +  G N+    VVK G +P  VKL+  S   +   ++ A+ NI   + +   +++  G + V  + +     K  + +   W +SN+   +           L+P +  ++ +  D     +  WA++ Y      + I  L+   ++  L+  L  ++ +I+   L AI N+       G  E+    I+ CG +  +  L +H+N  + K S  ++    +  E + Q  V
Sbjct:  237 CR---NKNPAPPIDAVEQ--ILPTLVRLLHHDDPEVLA-DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTN--PKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKA-DFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVV 507          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA2 (karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395])

HSP 1 Score: 335.88 bits (860), Expect = 1.417e-108
Identity = 177/483 (36.65%), Postives = 286/483 (59.21%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLE--VLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R + +KN  KD   +RR R + +VE+RKAKK+DQ+ KRRN V     D    +    N +   + ++++I K + S N+   L A  + RKLLS++K PPI++  + G IP  V  +       + FESAWALTNIASG ++ T+AVV  GAIP F+ L++     +SEQ++WAL NIAGD + +RD+++K+G +D +   + +   S L    LR++ W +SNLCR+K+   P   + ++LP L+R  ++  +D     D  WA+SY  D  ++ I  ++   +VP L+  L   E  IVTP+LRAIGN++ GTDEQ    I  G +     LL++    + KE+ W +SNI AG + QIQ  V+  ++  L+ V+   D+K+QKEA WAV+N  +    +  +YL++  +   ++ +L+  +  +++++LDA+  +F  A+K+G+ E      E+ GG+D IE+LQ HE+  +Y  S  ++
Sbjct:   13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRN-VSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVR--LLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLI 492          

HSP 2 Score: 61.2326 bits (147), Expect = 3.052e-9
Identity = 61/280 (21.79%), Postives = 124/280 (44.29%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIA-----GTDEQADAAIK-CGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACV 1148
            CR   +K   PPI+   +   +P LV+++  +  E+L  ++ WA++ +  G N+    VVK G +P  VKL+  S   +   ++ A+ NI   + +   +++  G + V  + +     K  + +   W +SN+   +           L+P +  ++ +  D     +  WA++ Y      + I  L+   ++  L+  L  ++ +I+   L AI N+       G  E+    I+ CG +  +  L +H+N  + K S  ++    +  E + Q  V
Sbjct:  237 CR---NKNPAPPIDAVEQ--ILPTLVRLLHHDDPEVLA-DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTN--PKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKA-DFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVV 507          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA3 (karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396])

HSP 1 Score: 333.183 bits (853), Expect = 1.258e-107
Identity = 179/485 (36.91%), Postives = 289/485 (59.59%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+      +E++E S  +   + +++ +  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W+I NLCR+K    P   + E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V+    +LLSH   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +LS  ++ VV ++LD ++ +   A    +        E+ GG++ IE LQ+HE+ DIY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP----QEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGD--EASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEII 481          

HSP 2 Score: 64.3142 bits (155), Expect = 2.753e-10
Identity = 62/295 (21.02%), Postives = 129/295 (43.73%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVI--AGTDEQADAAI--KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDY 1199
            CR   +K   PP+E   +   +P L  ++      IL  ++ WAL+ +  G N+  + V+ +G +P  V L+S    +V   ++ A+ NI   + +   +++   ++    N +     K ++ +   W +SN+         +     L+P+I   + +  D     +  WA+S   I  R D +  L+   ++P     L+ ++ ++V   L  + N++  AG +    A I  +CG +  +  L  H+N  + K +  ++    +G++     C     +IP  +  + G Y
Sbjct:  228 CR---NKDPPPPMETVQE--ILPALCVLIYHTDINILV-DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSH--PKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAK-GDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPC-----LIP--EATQGGTY 506          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA4 (karyopherin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6397])

HSP 1 Score: 332.798 bits (852), Expect = 1.510e-107
Identity = 176/478 (36.82%), Postives = 285/478 (59.62%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR RN+  VE+RK K+++ L KRRN+  +D+ ++    S  +    +++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV    D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D +++  ++ ++  GD+ +QKEAAWA+SN+  S       YL+  NV      +L+  +  VV ++LD +  +   A+   + E   N  E+ GG++ IE LQ HE+ DIY  +++I+
Sbjct:   15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICED----SDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED--EAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEII 481          
BLAST of Importin subunit alpha vs. Ensembl Human
Match: KPNA7 (karyopherin subunit alpha 7 [Source:HGNC Symbol;Acc:HGNC:21839])

HSP 1 Score: 300.827 bits (769), Expect = 2.792e-95
Identity = 169/481 (35.14%), Postives = 276/481 (57.38%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIK-DININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            RR  +K   KD    R+ R   S+E+RKAKK++Q  KRRNI     +    +  S++  K +   + + EI K + S +      A  + RK+LS++KNPP++   + G IP +V+ +  +    L FE+AWALTNIASG ++ T AVV+ GAI   ++L+S S   V EQ++WAL NIAGD  ++RD ++    I  +   ++     +  LR++ W +SNLCR+K+     + + ++LP +  ++ +  D     D  WALSY  D  +  I  ++   ++P L+  +   E  ++TPSLR +GN++ GTDEQ   AI  G++  +  LL H  P + KE+ W LSN+ AG    IQ  +  DV+ PL+ +++NG++K QKEA W V+N A  A     + L+++ V   +V +L+  +  +V+++LD +  +   A+K  + E LC+   E++GGID IE+LQ HE+  I   + +I+
Sbjct:   10 RRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNI-----TSFCPDTPSEKTAKGVAVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLL-ALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLL-QHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRSEKENLCL-LIEELGGIDRIEALQLHENRQIGQSALNII 482          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-3 (Importin subunit alpha-3 [Source:UniProtKB/Swiss-Prot;Acc:Q19969])

HSP 1 Score: 298.516 bits (763), Expect = 7.759e-95
Identity = 170/486 (34.98%), Postives = 276/486 (56.79%), Query Frame = 3
Query:   63 NRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLL---KSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            NR+  YKN  K+ +  +  RN+  V IRK K+E+ + KRRNI      +  IE  S+ +       + N +   +   +S +  + L A    RK+LS  +NPPI+D   +G +P+LV+ ++ + +  L FE+AWALTNIASG ++ T+AVV AGA+P+F++L+SC    V EQS+WAL NI GD   +RD  ++ GI+      +L+F +    +  LR+V W+I NLCR K    PS  ++  +     +++   D     D  WALSY  D  ++ I  +I  ++V  L+  L   + ++ T +LRA+GN++ GTDEQ    +  GV+  +  LL+H   ++ KE+ W +SNI AGN+ Q+Q   D  +M  ++ ++  GD+ +QKEAAWA+SN+  S        ++   V      +LSC ++ ++ ++LD +  +   A +    E   +  E+ GG+D IE+LQ HE+ DIY  +F+I+
Sbjct:    4 NRQAYYKNNAKE-QIGKEKRNEEVVSIRKDKREEAISKRRNI------NTQIEDDSETSTTPPGPFDANLLRLTVAAAQSSDPAEQLTAVQQARKMLSTDRNPPIDDLIGSGILPVLVQCLS-STDPNLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWALGNIIGDGPHFRDYCLELGIL----QPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPA-PSPAVVRTILPALSLLIHHQDTNILIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLAHYKEKINKEAVWFVSNITAGNQQQVQDVFDAGIMPMIIHLLDRGDFPTQKEAAWAISNVTISGRPNQVEQMVKLGVLRPFCAMLSCTDSQIIQVVLDGINNILKMAGEAA--EQVTSEIEECGGLDKIENLQNHENEDIYKLAFEII 474          

HSP 2 Score: 56.6102 bits (135), Expect = 2.621e-8
Identity = 52/277 (18.77%), Postives = 118/277 (42.60%), Query Frame = 3
Query:  393 IPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAI----KCGVIISVGHLLSHKNPRLVKESCWVLSNIIA-----GNESQIQACVDCDVMIPLLDVMRNG 1193
            +P L  ++      IL  ++ WAL+ +  G N+H + V++A  +   V L+     +V   ++ A+ NI   + +   +++  G++  +   +  +  K+   +   W +SN+               ++P+I  ++ +  D     +  WA+S   I  R + +  ++   ++    A L+  + +I+   L  I N++    E A+       +CG +  + +L +H+N  + K +  ++ N  +     GN    Q+      + P+ D    G
Sbjct:  237 LPALSLLIHHQDTNIL-IDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLAHYKEKIN--KEAVWFVSNITAGNQQQVQDVFDAGIMPMIIHLL-DRGDFPTQKEAAWAISNVTISGRPNQVEQMVKLGVLRPFCAMLSCTDSQIIQVVLDGINNILKMAGEAAEQVTSEIEECGGLDKIENLQNHENEDIYKLAFEIIDNFFSSDDETGNVEGAQSSAFGGDVPPVPDAPNGG 509          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-2 (Importin subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:P91276])

HSP 1 Score: 264.233 bits (674), Expect = 1.981e-81
Identity = 172/500 (34.40%), Postives = 282/500 (56.40%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIV-IDDLSDENIEVSSKENVKEIKD---ININEIPKLLKSGNITQ--MLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVK-HGIIDVVKNCILRFWSKLEVL-----RHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEI---NDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSH-KNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADK--IGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E  R   YKN  K  E LRR R + SVEIRK K  D + KRRNIV +D+  +   E+   E +   +    ++ +EI  +L S N ++  M+    S RK LSK KNPPI++    G +  LV+ ++  +NE + +E+AWALTNI SG  + T A V+AG     + L    + Q+SEQ++WA++NIAGDS++ RD ++K HG+       ++    K++ L     R + W  SN+CRHK+ + P    +E+L ++ + +V++    D     D  WA+SY  D  D+ I     + ++P ++A     E  +V P+LR +GNV  G D    A I  G +  +  L+   ++  +VKE CW++SNIIAG + QIQA +D +++  L++V+++GD+K Q EA+WA+SN+A    ++  + +L +NV  A+   L     D++   L+ +  L          ++++  +  E+ GG+D +E LQE +S  IYT+++ I+
Sbjct:   18 EGGRLQQYKNLTK-HEELRRRRTECSVEIRKQKGADMMMKRRNIVDVDEGGNSESELEEPEKISHQQSSTRLSNDEIRAIL-SNNPSEDDMVRCFESLRKSLSKTKNPPIDEVIHCGLLQALVQALS-VENERVQYEAAWALTNIVSGSTEQTIAAVEAGVTIPLIHLSVHQSAQISEQALWAVANIAGDSSQLRDYVIKCHGV-----EALMHLMEKVDQLGDSHVRTIAWAFSNMCRHKNPHAP----LEVLRVLSKGLVKLVQHTDRQVRQDACWAVSYLTDGPDEQIELARESGVLPHVVAFFKEAE-NLVAPALRTLGNVATGNDSLTQAVIDLGSLDEILPLMEKTRSSSIVKECCWLVSNIIAGTQKQIQAVLDANLLPVLINVLKSGDHKCQFEASWALSNLAQGGTNRQVVAMLEDNVVPALCQALLQTNTDMLNNTLETLYTLMLTVQNGYPHKVDILHDQVEENGGLDSLERLQESQSEQIYTQAYRII 504          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: F53B2.5 (pep chromosome:WBcel235:IV:12528529:12531166:-1 gene:WBGene00009956.1 transcript:F53B2.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F53B2.5)

HSP 1 Score: 84.3445 bits (207), Expect = 3.751e-17
Identity = 83/360 (23.06%), Postives = 166/360 (46.11%), Query Frame = 3
Query:  258 ININEIPKLLKSGNITQMLDAATSCRKLLSKQKN----PPIEDFY---KNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVV-KNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVE---INDVACTCDLNWALSYAIDSRDDI--INALIANELV--PVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAI---KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACV-DCDVMIP-LLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLL 1277
             +I+ I  +L+S    Q+  A    RK  + Q +       E FY   KNG +  L     D  +E+    + W +TN+     + T   V +  + + +KL+     ++S Q++WA++NIA D +  +       ++ ++ +N    +       R + W ++N+     T  PS     L+  +  I+++   ++++ C   + W L+  +D+  D   I+ L++   V   +L   +++ +       LR IGN+  G D Q D  +   K  V++++    +  +P    E+ W++SN++AG    +   + D D     ++  +  GD + +KE  W + N+  +A D+H+ YLL
Sbjct:   22 FDISFIISMLESSCRIQLSTALHFFRKAFANQSDLSNIALKEQFYGRIKNGVLNALRNQTLDIDSEV---NAVWIITNMCCISQEVTHLFVNSNCLDILIKLVRSQNARLSSQTVWAIANIAADCSSCKLKCRSPKLLKILARNLQTSYKLDDADRRQLIWCVNNIFSGGRTTMPSPVARSLICALSAILLDTDAVDNMGCGSMILWTLANLVDNSLDTTRIDMLLSQNYVVEHILEKFIDQTDKSCNVSCLRLIGNIAVGNDVQTDLLVDNPKFRVVMNI----AMSSPEHHSEAAWIISNVVAGAPRHVDYIMDDPDAFYEWVMAGIHTGDKRLRKECLWIIGNLLATA-DEHQTYLL 373          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-1 (Importin subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q22560])

HSP 1 Score: 71.2478 bits (173), Expect = 6.781e-13
Identity = 54/208 (25.96%), Postives = 105/208 (50.48%), Query Frame = 3
Query:  903 ELVPVLIANLNRQECEIVTPSLRA-IGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCIN-------AFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +L   L+ANL R +     P ++A I ++I  T    +  I  G++  +   ++     + +E C+++SNI    E  I   +   V+  +  VM   +Y+S++EAA+ + +   SAN KH  Y++   +  A   +L+C +  +V  +LDA+  L     + G++ L  +         E++G  + +E L E +SVDI+ +++ I+
Sbjct:  281 KLCSKLVANL-RNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVN--VSYMSQEVCFIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKHLEYVVELGMLSAFTDLLTCMDVSLVSYILDAIYLLL----QFGEMRLLPDNSNPVAIKLEEIGCREKLEFLCESQSVDIHARAYTII 481          
BLAST of Importin subunit alpha vs. Ensembl Celegans
Match: ima-1 (Importin subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:Q22560])

HSP 1 Score: 71.2478 bits (173), Expect = 6.781e-13
Identity = 54/208 (25.96%), Postives = 105/208 (50.48%), Query Frame = 3
Query:  903 ELVPVLIANLNRQECEIVTPSLRA-IGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCIN-------AFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +L   L+ANL R +     P ++A I ++I  T    +  I  G++  +   ++     + +E C+++SNI    E  I   +   V+  +  VM   +Y+S++EAA+ + +   SAN KH  Y++   +  A   +L+C +  +V  +LDA+  L     + G++ L  +         E++G  + +E L E +SVDI+ +++ I+
Sbjct:  281 KLCSKLVANL-RNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFVN--VSYMSQEVCFIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKHLEYVVELGMLSAFTDLLTCMDVSLVSYILDAIYLLL----QFGEMRLLPDNSNPVAIKLEEIGCREKLEFLCESQSVDIHARAYTII 481          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0301189)

HSP 1 Score: 325.094 bits (832), Expect = 4.898e-105
Identity = 177/483 (36.65%), Postives = 285/483 (59.01%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIV-IDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E NR   +KN  KD + +RR RN+ +VE+RK K+E+ + KRRN+  +D  +DE  ++SS  ++K++             +    Q L A  + RKLLS  KNPPI D  ++  +P+LV+ +  + + +L FE+AWALTNIASG +  T  VV AGA+P+F++L++     V EQ++WAL NI GD    RD ++KHG++  + + I +    +  LR+V W+I NLCR+K    P++ I E+LP +  +++   D     D  WA+SY  D  +D I  +I + +VP LI  L   E ++ T +LRA+GN++ G+DEQ    +    +     LLSH   ++ KE+ W LSNI AGN+SQ+QA ++  ++  +++ +  G++++QKEAAWA+SN+  S N +    L+   V      +LSC +  V+ ++LD +  +   AD    +E   N  E+  G+  IE LQ HE+V+IY  +++I+
Sbjct:    5 EQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAK-------AAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFI-KPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALN-VLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVAD--SHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEII 476          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0082106)

HSP 1 Score: 325.094 bits (832), Expect = 4.898e-105
Identity = 177/483 (36.65%), Postives = 285/483 (59.01%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIV-IDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E NR   +KN  KD + +RR RN+ +VE+RK K+E+ + KRRN+  +D  +DE  ++SS  ++K++             +    Q L A  + RKLLS  KNPPI D  ++  +P+LV+ +  + + +L FE+AWALTNIASG +  T  VV AGA+P+F++L++     V EQ++WAL NI GD    RD ++KHG++  + + I +    +  LR+V W+I NLCR+K    P++ I E+LP +  +++   D     D  WA+SY  D  +D I  +I + +VP LI  L   E ++ T +LRA+GN++ G+DEQ    +    +     LLSH   ++ KE+ W LSNI AGN+SQ+QA ++  ++  +++ +  G++++QKEAAWA+SN+  S N +    L+   V      +LSC +  V+ ++LD +  +   AD    +E   N  E+  G+  IE LQ HE+V+IY  +++I+
Sbjct:    5 EQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAK-------AAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFI-KPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALN-VLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVAD--SHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEII 476          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0082108)

HSP 1 Score: 325.094 bits (832), Expect = 4.898e-105
Identity = 177/483 (36.65%), Postives = 285/483 (59.01%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIV-IDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E NR   +KN  KD + +RR RN+ +VE+RK K+E+ + KRRN+  +D  +DE  ++SS  ++K++             +    Q L A  + RKLLS  KNPPI D  ++  +P+LV+ +  + + +L FE+AWALTNIASG +  T  VV AGA+P+F++L++     V EQ++WAL NI GD    RD ++KHG++  + + I +    +  LR+V W+I NLCR+K    P++ I E+LP +  +++   D     D  WA+SY  D  +D I  +I + +VP LI  L   E ++ T +LRA+GN++ G+DEQ    +    +     LLSH   ++ KE+ W LSNI AGN+SQ+QA ++  ++  +++ +  G++++QKEAAWA+SN+  S N +    L+   V      +LSC +  V+ ++LD +  +   AD    +E   N  E+  G+  IE LQ HE+V+IY  +++I+
Sbjct:    5 EQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAK-------AAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFI-KPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALN-VLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVAD--SHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEII 476          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Kap-alpha3 (gene:FBgn0027338 transcript:FBtr0082107)

HSP 1 Score: 325.094 bits (832), Expect = 4.898e-105
Identity = 177/483 (36.65%), Postives = 285/483 (59.01%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIV-IDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E NR   +KN  KD + +RR RN+ +VE+RK K+E+ + KRRN+  +D  +DE  ++SS  ++K++             +    Q L A  + RKLLS  KNPPI D  ++  +P+LV+ +  + + +L FE+AWALTNIASG +  T  VV AGA+P+F++L++     V EQ++WAL NI GD    RD ++KHG++  + + I +    +  LR+V W+I NLCR+K    P++ I E+LP +  +++   D     D  WA+SY  D  +D I  +I + +VP LI  L   E ++ T +LRA+GN++ G+DEQ    +    +     LLSH   ++ KE+ W LSNI AGN+SQ+QA ++  ++  +++ +  G++++QKEAAWA+SN+  S N +    L+   V      +LSC +  V+ ++LD +  +   AD    +E   N  E+  G+  IE LQ HE+V+IY  +++I+
Sbjct:    5 EQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKLAK-------AAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFI-KPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALN-VLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVAD--SHVEAVANCIEECEGLAKIERLQSHENVEIYKLAYEII 476          
BLAST of Importin subunit alpha vs. Ensembl Fly
Match: Pen (gene:FBgn0267727 transcript:FBtr0079937)

HSP 1 Score: 311.612 bits (797), Expect = 1.306e-99
Identity = 169/482 (35.06%), Postives = 288/482 (59.75%), Query Frame = 3
Query:   63 NRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNN-NVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +R+  YK    + +  R  R++ ++E+RK+KKEDQ+ KRRNI  +DL+    E++ +  V+    ++++EI   + S +  +      S RK+LS+++NPPI+    +G +P+ ++ + +  N +L FE+AWALTNIASG +  T  V++  A+P FV L+   +  ++EQ++WAL NIAGD A  RD+++ H +ID +   ++   + L  LR++ WL+SNLCR+K+ + P    ++ L  +   ++   D+    D  WALSY  D  +  I A++ ++ VP L+  L   E  I+ P+LR++GN++ GTD+Q D  I  G +  +G LL H    +VKE+ W +SNI AGN+ QIQA +   +   L  V+  GD+K+QKEAAWAV+N   S   +  + L+    +    + +L   +   + ++   +  LF  A+K+G  E LC+   E++GG+D +E+LQ+HE+ ++Y K++ I+
Sbjct:    8 SRQGSYKANSINTQDSRMRRHEVTIELRKSKKEDQMFKRRNINDEDLTSPLKELNGQSPVQ----LSVDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGIL-PLINNETPLSFLRNIVWLMSNLCRNKNPS-PPFDQVKRLLPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVTNTTTSGTPEQIVDLIEKYKILKPFIDLLDTKDPRTIKVVQTGLSNLFALAEKLGGTENLCL-MVEEMGGLDKLETLQQHENEEVYKKAYAII 482          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna2 (karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [Source:ZFIN;Acc:ZDB-GENE-040718-22])

HSP 1 Score: 346.28 bits (887), Expect = 5.541e-113
Identity = 187/486 (38.48%), Postives = 288/486 (59.26%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIE-VSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEV-----LRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   +KN  KD   LRR R + +VE+RKAKK++Q+ KRRN+      DE    +  K    + +   + EI   + S N+   + A  + RKLLS++++PPI+     G IP  V  ++   +  + FE+AWALTNIASG +  T AVV+ GAIP F+ L+S     +SEQ++WAL NIAGD + YRD ++KHG I  +    L     L V     LR+V W +SNLCR+K+   P   + ++LP +   +++ +D     D  WA+SY  D  +D I  ++   +VP L+  L   E  IVTPSLR+IGN++ GTDEQ  A ++ G +     LL H+   + KE+ W LSNI AG + QIQ  ++  ++  L++V+R GDYK+QKEA WAV+N  +    +  +YL+  NV   ++ +LS  ++  ++++LDA+  +F   +KIG++E LC+   E+ GG+D IE+LQ HE+  +Y  S +++
Sbjct:   10 RLTQFKNKGKDATELRRRRIEVNVELRKAKKDEQILKRRNV--SSFPDEATSPLQEKSQNCQAQHWTVEEIVNGVNSNNLETQVQATQAARKLLSRERHPPIDRIISAGLIPKFVGFLSLVDSPPIQFEAAWALTNIASGTSDQTSAVVQGGAIPAFISLISSPHAHISEQAVWALGNIAGDGSGYRDRVIKHGAIPPL--LALLAVPDLSVFPAGYLRNVTWTLSNLCRNKNPAPPLEAVKQILPTLI-CLLQHSDKEVLADTCWAISYLTDGPNDRIEVVVNAGVVPRLVQLLASGELSIVTPSLRSIGNIVTGTDEQTQAVLEAGALPMFPALLRHQKSNIQKEASWTLSNITAGRDYQIQEVINAGIVPYLVEVLRRGDYKTQKEAVWAVTNYTSGGTVEQVVYLVQANVLEPLLNLLSTKDSKTILVILDAITNIFLAGEKIGEVEKLCL-MIEECGGLDKIEALQSHENEMVYKASLNLI 489          

HSP 2 Score: 57.7658 bits (138), Expect = 1.943e-8
Identity = 57/276 (20.65%), Postives = 125/276 (45.29%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS--YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAI------KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQ 1133
            CR   +K   PP+E   +   +P L+ ++  +  E+L  ++ WA++ +  G N   E VV AG +P  V+L++     +   S+ ++ NI   + +    +++ G + +    +LR   K  + +   W +SN+   +           ++P + E++    D     +  WA++   +  + + ++  + AN L P L+  L+ ++ + +   L AI N+    ++  +         +CG +  +  L SH+N  + K S  ++    +G E +
Sbjct:  234 CR---NKNPAPPLEAVKQ--ILPTLICLLQHSDKEVLA-DTCWAISYLTDGPNDRIEVVVNAGVVPRLVQLLASGELSIVTPSLRSIGNIVTGTDEQTQAVLEAGALPMFP-ALLRH-QKSNIQKEASWTLSNITAGRDYQIQEVINAGIVPYLVEVLRR-GDYKTQKEAVWAVTNYTSGGTVEQVVYLVQANVLEP-LLNLLSTKDSKTILVILDAITNIFLAGEKIGEVEKLCLMIEECGGLDKIEALQSHENEMVYKASLNLIEKYFSGEEEE 499          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna3 (karyopherin alpha 3 (importin alpha 4) [Source:ZFIN;Acc:ZDB-GENE-030616-541])

HSP 1 Score: 332.798 bits (852), Expect = 8.841e-108
Identity = 178/485 (36.70%), Postives = 291/485 (60.00%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+      +E++E S  ++  + +++ ++ I +   S N    L A  + RKLLS  +NPPI+D  K G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVVK+ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F +    +  LR+V W+I NLCR+K    P   + E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V+     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +LS  ++ VV ++LD ++ +   A +  +        E+ GG++ IE+LQ+HE+ DIY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP----QEESLEDSDVDSDFKGQNVTLDAILQNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKCGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLTHFSTLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGE--EASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEII 481          

HSP 2 Score: 63.929 bits (154), Expect = 2.569e-10
Identity = 62/278 (22.30%), Postives = 123/278 (44.24%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNC-ILRFWSKL------EVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVI--AGTDEQADAAI--KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNE 1127
            CR   +K   PP+E   +   +P L  ++      IL  ++ WAL+ +  G N+  + V+ +G +P  V L+S    +V   ++ A+ NI   + +            VV NC +L  +S L      ++ +   W +SN+         +     L+P+I   + +  D     +  WA+S   I  R D +  L+   ++P     L+ ++ ++V   L  + N++  AG +    A I  +CG +  + +L  H+N  + K +  ++    +G++
Sbjct:  228 CR---NKDPPPPMETVQE--ILPALCVLIYHTDINILV-DTVWALSYLTDGGNEQIQMVIDSGVVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQ---------TQVVLNCDVLTHFSTLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAK-GDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDD 489          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna4 (karyopherin alpha 4 (importin alpha 3) [Source:ZFIN;Acc:ZDB-GENE-030131-5584])

HSP 1 Score: 331.257 bits (848), Expect = 4.415e-107
Identity = 176/478 (36.82%), Postives = 283/478 (59.21%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR R +  VE+RK K+++ L KRRN+  +D+ D++  V    +    ++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV    D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D +++  ++ ++  GD+ +QKEAAWA+SN+  S       YL+   V      +L+  +  VV ++LD +  +   AD   + E   N  E+ GG++ IE LQ HE+ DIY  +++I+
Sbjct:   15 FKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDICDDSDAVGDFRS----QNTSLEAIVQNATSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALGHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIILLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADD--EAETVANLIEECGGLEKIEQLQNHENEDIYKLAYEII 481          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna7 (karyopherin alpha 7 (importin alpha 8) [Source:ZFIN;Acc:ZDB-GENE-040426-2023])

HSP 1 Score: 311.997 bits (798), Expect = 1.126e-99
Identity = 172/478 (35.98%), Postives = 290/478 (60.67%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENV--KEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEV--LRHVCWLISNLCRHKSTNFPS-SGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIY 1481
            R + +KN  K+   LR  R    VE+RKA++ + + KRRNI    L DE   +S + N   +++    I EI   + +    +  +   + RKLLS+++NPP+++  + G +   V+ +  N +  L FE+AW+LTN+ASG + HT+ VV+ GA+P F+ L++     +SEQ++WAL NIAGD + YRD ++  G+I  +   + R      V  LR++ W +SNLCR+K+  FP  S + ++LP I +++   +D +   D  WA+SY  D  ++ I+ +I   ++  L+  L  +E  +VTP+LR+IGN+++G+D Q  AAI  GV+ ++  L+ H+   + KE+ W +SNI AG   QIQ  + C ++ PL+D++RNGD+K+Q+EA WAV+N  +    +  ++L+      AI+ +L   +   V+++LDA+  +F  A+K+G+++ LC+   E+VGG+D IE LQ HE+  +Y
Sbjct:   10 RMSKFKNKGKEPTKLRDRRVAECVELRKAQRVEGIMKRRNIT--SLGDEE-PLSPEFNTDNEQVICTTIEEIVANVNTDCPEKQRNGCQAARKLLSRERNPPLKEIIEAGLLTRFVEFLGRNDDPTLQFEAAWSLTNVASGTSWHTQQVVEHGAVPAFIALLASPLLNISEQAVWALGNIAGDGSSYRDALIDCGVIPAL---LARLTPDAPVGYLRNLTWTLSNLCRNKNP-FPRFSAVQQMLPSIIQLLHH-SDKSILSDACWAISYLTDGPNERIDVIIKAGILTRLVELLGFEELAVVTPALRSIGNIVSGSDLQTQAAIDAGVLSALPKLMRHQKSSVQKEAAWAVSNIAAGPCQQIQQLITCGLLAPLVDLLRNGDFKTQREAVWAVTNYTSGGTVEQVVHLVKCGALEAILNLLQVKDTKTVLVILDAISNIFLAAEKLGEVDKLCL-LVEEVGGLDRIEFLQNHENNAVY 478          
BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Match: kpna5 (karyopherin alpha 5 (importin alpha 6) [Source:NCBI gene;Acc:553205])

HSP 1 Score: 275.404 bits (703), Expect = 2.145e-85
Identity = 161/492 (32.72%), Postives = 282/492 (57.32%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIE-------VSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKN-GTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIG-QLELCINAF----EDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   YKN   + + +RR R +  +++RK K+E+QL KRRN+ +    +  +E       VSS   V   + +   ++ +++ S +  Q L A    RKLLSK+ NPPI++     G +   V+ +  + N  L FE+AWALTNIASG  +HT+ V++ GA+P+F++L++   + V EQ++WAL NIAGD+A+ RD ++  GI+  ++  + +  ++L   R+  W +SNLCR K+     + +   L ++  ++   +D     D  WALSY  D  +D I  +I + +   L+  L   + ++V+P+LRA+GN++ G D Q    + C  +  + HLLS     + KE+CW +SNI AGN +QIQA +D +V   L+++++  +++++KEAAWA++N  +    +   YL++ N    +  +L+  ++ +V + L+ +  +    ++   Q    IN +    E+  G+D IE LQ HE+ +IY K+FD++
Sbjct:   13 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVSLPPGDESMLECPIQDPDVSSTVPVSG-EGVITQDVIQMIFSEDPDQQLIATQKFRKLLSKEPNPPIDEVIGTPGVVNRFVEFLRRSDNCTLQFEAAWALTNIASGTFQHTKVVIETGAVPIFIELLNSEYEDVQEQAVWALGNIAGDNAECRDYVLNCGILPSLQQLLAKS-NRLTTTRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSRLLFS-SDPDVLADACWALSYLSDGPNDKIQTVIDSGVCRRLVELLMHSDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIKKEACWTVSNITAGNRAQIQAVIDSNVFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLNTIKPMCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLI 501          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kpna7 (karyopherin alpha 7 (importin alpha 8) [Source:NCBI gene;Acc:100216104])

HSP 1 Score: 350.132 bits (897), Expect = 2.703e-114
Identity = 178/483 (36.85%), Postives = 298/483 (61.70%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKE---IKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   +KN  KD   LRR R + +VE+RKAKK++Q+ KRRN+       E + +S ++NV +   +  +++ EI + + SG+    L +  + RK+LS+++NPP+ D  + G IP LV  ++ + N  L FE+AWALTNIASG +  T++VV  GAIP F+ L+S     +SEQ++WAL NIAGD   YRD ++   +I  +   ++   + +  LR++ W +SNLCR+K+   P S ++++LP++ +++    D     D  WA+SY  D  +D I+ ++   +V  LI  +   E  I+TPSLR +GN++ GTD+Q  AAI  GV+  +  LL H+ P + KE+ W LSNI AG   QIQ  + C ++ PL+D+++ GD+K+QKEA WAV+N  +    +  + L+   V   ++ +L+  ++  ++++LDA+  +F  A+K+G+ E LC+   E++GG++ IE+LQ H++  +Y  +  ++
Sbjct:   10 RMRKFKNKGKDTAELRRRRVEVNVELRKAKKDEQILKRRNVCFP----EELVLSPEKNVMQSMQVPSLSLEEIVQGMNSGDTENELRSTQAARKMLSRERNPPLNDIIEAGLIPKLVDFLSRHDNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPMYRDSLINCNVIPPLL-ALVNPQTPIGYLRNITWTLSNLCRNKNPYPPMSAVLQILPVLTQLLHH-EDKDILSDTCWAMSYLTDGSNDRIDVVVKTGIVERLIQLMYSPELSILTPSLRTVGNIVTGTDKQTQAAIDVGVLSILPQLLRHQKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSPLVDLLKKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAEKLGEQEKLCL-LVEELGGLEKIEALQTHDNHMVYHAALALI 485          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kpna7 (karyopherin alpha 7 (importin alpha 8) [Source:NCBI gene;Acc:100216104])

HSP 1 Score: 340.887 bits (873), Expect = 3.331e-111
Identity = 173/471 (36.73%), Postives = 293/471 (62.21%), Query Frame = 3
Query:  102 ESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKE---IKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            + LRR R + +VE+RKAKK++Q+ KRRN+       E + +S ++NV +   +  +++ EI + + SG+    L +  + RK+LS+++NPP+ D  + G IP LV  ++ + N  L FE+AWALTNIASG +  T++VV  GAIP F+ L+S     +SEQ++WAL NIAGD   YRD ++   +I  +   ++   + +  LR++ W +SNLCR+K+   P S ++++LP++ +++    D     D  WA+SY  D  +D I+ ++   +V  LI  +   E  I+TPSLR +GN++ GTD+Q  AAI  GV+  +  LL H+ P + KE+ W LSNI AG   QIQ  + C ++ PL+D+++ GD+K+QKEA WAV+N  +    +  + L+   V   ++ +L+  ++  ++++LDA+  +F  A+K+G+ E LC+   E++GG++ IE+LQ H++  +Y  +  ++
Sbjct:    2 DELRRRRVEVNVELRKAKKDEQILKRRNVCFP----EELVLSPEKNVMQSMQVPSLSLEEIVQGMNSGDTENELRSTQAARKMLSRERNPPLNDIIEAGLIPKLVDFLSRHDNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPMYRDSLINCNVIPPLL-ALVNPQTPIGYLRNITWTLSNLCRNKNPYPPMSAVLQILPVLTQLLHH-EDKDILSDTCWAMSYLTDGSNDRIDVVVKTGIVERLIQLMYSPELSILTPSLRTVGNIVTGTDKQTQAAIDVGVLSILPQLLRHQKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSPLVDLLKKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAEKLGEQEKLCL-LVEELGGLEKIEALQTHDNHMVYHAALALI 465          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: acp4 (acid phosphatase 4 [Source:Xenbase;Acc:XB-GENE-960831])

HSP 1 Score: 337.035 bits (863), Expect = 3.348e-109
Identity = 181/486 (37.24%), Postives = 280/486 (57.61%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEV--SSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKL---EVLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   +KN  KD   +RR R + +VE+RKAKK+DQ+ KRRN+      DE         +N +     ++ EI + + S ++   L A  + RKLLS+++ PPI+   + G IP LV  +       + FE+AWALTNIASG +  T+AVV+ G +P F+ L++     +SEQ++WAL NIAGD + YRD+++KHG +  +   +            LR+V W +SNLCR+K+   P   I ++LP L+R  ++  +D     D  WA+SY  D  +D IN ++   LVP ++  L   E  IVTP LR +GN++ GTDEQ    +  G +     LL+H    + KE+ W LSNI AG + QIQ  V+  ++  L++++R  DYK+QKEA WAV+N  +       +YL+  +V   +  +LS  ++  V+++LDA   +F  A+K+G+ E LC+   E+ GG+D IE+LQ HE+  +Y  S  ++
Sbjct:    9 RLTRFKNKGKDTTEMRRRRIEVNVELRKAKKDDQMLKRRNV--STFPDEPTSPLQEKNQNGQTSTQWSVEEIVRGVASSSLEIQLQATQAARKLLSREREPPIDRIIQAGLIPKLVAFLARTDCSPIQFEAAWALTNIASGTSDQTKAVVEGGGVPAFISLLASPHPHISEQAVWALGNIAGDGSAYRDLVIKHGAVGPLLALLADPDLSTLATGYLRNVTWTLSNLCRNKNPAPPLDAIQQILPTLVR--LLHHDDREVLADTCWAVSYLTDGSNDRINVVVGTGLVPRIVQLLGCGELTIVTPCLRTVGNIVTGTDEQTQVVLDAGALSVFAELLTHHKNNIQKEAAWTLSNITAGRQDQIQEVVNHGLIPYLIEILRKADYKTQKEAIWAVTNYTSGGTIDQIIYLVQCSVIEPLSNLLSVKDSKTVLVILDAFTNVFAAAEKLGETEKLCL-MVEECGGLDRIEALQSHENEQVYKASAGLI 489          

HSP 2 Score: 56.6102 bits (135), Expect = 6.738e-8
Identity = 56/275 (20.36%), Postives = 117/275 (42.55%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAI------KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQ 1133
            CR   +K   PP++   +   +P LV+++  +  E+L  ++ WA++ +  G N     VV  G +P  V+L+ C    +    +  + NI   + +   +++  G + V    +     K  + +   W +SN+   +           L+P + EI+ +  D     +  WA++ Y      D I  L+   ++  L   L+ ++ + V   L A  NV A  ++  +         +CG +  +  L SH+N ++ K S  ++    +  + +
Sbjct:  234 CR---NKNPAPPLDAIQQ--ILPTLVRLLHHDDREVLA-DTCWAVSYLTDGSNDRINVVVGTGLVPRIVQLLGCGELTIVTPCLRTVGNIVTGTDEQTQVVLDAGALSVFAELLTHH--KNNIQKEAAWTLSNITAGRQDQIQEVVNHGLIPYLIEILRKA-DYKTQKEAIWAVTNYTSGGTIDQIIYLVQCSVIEPLSNLLSVKDSKTVLVILDAFTNVFAAAEKLGETEKLCLMVEECGGLDRIEALQSHENEQVYKASAGLIEKYFSAEDGE 499          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: kpna3 (karyopherin alpha 3 (importin alpha 4) [Source:NCBI gene;Acc:548814])

HSP 1 Score: 330.102 bits (845), Expect = 1.601e-106
Identity = 176/485 (36.29%), Postives = 290/485 (59.79%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+      +E++E S  +   + +++ +  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F +    +  LR+V W+I NLCR+K    P   + E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V+    +LL+H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +LS  ++ VV ++LD ++ +   A    +        E+ GG++ IE+LQ+HE+ +IY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP----QEESLEDSDVDGDFKSQNVTLEAILQNATSDNPAIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLEADDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSLHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFHNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCSLLSVKDSQVVQVVLDGLKNILIMAGD--EASTIAEIIEECGGLEKIEALQQHENEEIYKLAFEII 481          

HSP 2 Score: 67.3958 bits (163), Expect = 3.192e-11
Identity = 57/271 (21.03%), Postives = 122/271 (45.02%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVI--AGTDEQADAAI--KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNE 1127
            CR   +K   PP+E   +   +P L  ++      IL  ++ WAL+ +  G N+  + V+ +G +P  V L+S    +V   ++ A+ NI   + +   +++   ++    N +     K ++ +   W +SN+         +     L+P+I   + +  D     +  WA+S   I  R D +  L+   ++P   + L+ ++ ++V   L  + N++  AG +    A I  +CG +  +  L  H+N  + K +  ++    +G++
Sbjct:  228 CR---NKDPPPPMETVQE--ILPALCVLIYHTDINILV-DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFHNLLTH--PKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAK-GDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCSLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEALQQHENEEIYKLAFEIIDQYFSGDD 489          
BLAST of Importin subunit alpha vs. Ensembl Xenopus
Match: acp4 (acid phosphatase 4 [Source:Xenbase;Acc:XB-GENE-960831])

HSP 1 Score: 329.331 bits (843), Expect = 4.116e-106
Identity = 176/475 (37.05%), Postives = 276/475 (58.11%), Query Frame = 3
Query:   99 FESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEV--SSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKL---EVLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            ++ +RR R + +VE+RKAKK+DQ+ KRRN+      DE         +N +     ++ EI + + S ++   L A  + RKLLS+++ PPI+   + G IP LV  +       + FE+AWALTNIASG +  T+AVV+ G +P F+ L++     +SEQ++WAL NIAGD + YRD+++KHG +  +   +            LR+V W +SNLCR+K+   P   I ++LP L+R  ++  +D     D  WA+SY  D  +D IN ++   LVP ++  L   E  IVTP LR +GN++ GTDEQ    +  G +     LL+H    + KE+ W LSNI AG + QIQ  V+  ++  L++++R  DYK+QKEA WAV+N  +       +YL+  +V   +  +LS  ++  V+++LDA   +F  A+K+G+ E LC+   E+ GG+D IE+LQ HE+  +Y  S  ++
Sbjct:   22 WQEMRRRRIEVNVELRKAKKDDQMLKRRNV--STFPDEPTSPLQEKNQNGQTSTQWSVEEIVRGVASSSLEIQLQATQAARKLLSREREPPIDRIIQAGLIPKLVAFLARTDCSPIQFEAAWALTNIASGTSDQTKAVVEGGGVPAFISLLASPHPHISEQAVWALGNIAGDGSAYRDLVIKHGAVGPLLALLADPDLSTLATGYLRNVTWTLSNLCRNKNPAPPLDAIQQILPTLVR--LLHHDDREVLADTCWAVSYLTDGSNDRINVVVGTGLVPRIVQLLGCGELTIVTPCLRTVGNIVTGTDEQTQVVLDAGALSVFAELLTHHKNNIQKEAAWTLSNITAGRQDQIQEVVNHGLIPYLIEILRKADYKTQKEAIWAVTNYTSGGTIDQIIYLVQCSVIEPLSNLLSVKDSKTVLVILDAFTNVFAAAEKLGETEKLCL-MVEECGGLDRIEALQSHENEQVYKASAGLI 491          

HSP 2 Score: 55.4546 bits (132), Expect = 1.699e-7
Identity = 56/275 (20.36%), Postives = 117/275 (42.55%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAI------KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQ 1133
            CR   +K   PP++   +   +P LV+++  +  E+L  ++ WA++ +  G N     VV  G +P  V+L+ C    +    +  + NI   + +   +++  G + V    +     K  + +   W +SN+   +           L+P + EI+ +  D     +  WA++ Y      D I  L+   ++  L   L+ ++ + V   L A  NV A  ++  +         +CG +  +  L SH+N ++ K S  ++    +  + +
Sbjct:  236 CR---NKNPAPPLDAIQQ--ILPTLVRLLHHDDREVLA-DTCWAVSYLTDGSNDRINVVVGTGLVPRIVQLLGCGELTIVTPCLRTVGNIVTGTDEQTQVVLDAGALSVFAELLTHH--KNNIQKEAAWTLSNITAGRQDQIQEVVNHGLIPYLIEILRKA-DYKTQKEAIWAVTNYTSGGTIDQIIYLVQCSVIEPLSNLLSVKDSKTVLVILDAFTNVFAAAEKLGETEKLCLMVEECGGLDRIEALQSHENEQVYKASAGLIEKYFSAEDGE 501          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Gm10184 (predicted pseudogene 10184 [Source:MGI Symbol;Acc:MGI:3704480])

HSP 1 Score: 340.117 bits (871), Expect = 2.077e-110
Identity = 181/485 (37.32%), Postives = 288/485 (59.38%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNI--VIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLE--VLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R N +KN  KD   +RR R + +VE+RKAKK++Q+ KRRN+    DD +     +    N +   + ++ +I K + S N+   L A  + RKLLS++K PPI++  + G IP  V  +       + FESAWALTNIASG ++ T+AVV  GAIP F+ L++     +SEQ++WAL NIAGD + +RD+++KHG ID +   + +   S L    LR++ W +SNLCR+K+   P   + ++LP L+R  ++  ND     D  WA+SY  D  ++ I  ++   +VP L+  L   E  IVTP+LRAIGN++ GTDEQ    I  G +     LL++    + KE+ W +SNI AG + QIQ  V+  ++  L+ V+   D+K+QKEAAWA++N  +    +  +YL++  +   ++ +LS  +  ++ ++LDA+  +F  A+K+G+ E      E+ GG+D IE+LQ HE+  +Y  S +++
Sbjct:   13 RLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSP---LQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVR--LLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLI 492          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna2 (karyopherin (importin) alpha 2 [Source:MGI Symbol;Acc:MGI:103561])

HSP 1 Score: 340.117 bits (871), Expect = 2.077e-110
Identity = 181/485 (37.32%), Postives = 288/485 (59.38%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNI--VIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLE--VLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R N +KN  KD   +RR R + +VE+RKAKK++Q+ KRRN+    DD +     +    N +   + ++ +I K + S N+   L A  + RKLLS++K PPI++  + G IP  V  +       + FESAWALTNIASG ++ T+AVV  GAIP F+ L++     +SEQ++WAL NIAGD + +RD+++KHG ID +   + +   S L    LR++ W +SNLCR+K+   P   + ++LP L+R  ++  ND     D  WA+SY  D  ++ I  ++   +VP L+  L   E  IVTP+LRAIGN++ GTDEQ    I  G +     LL++    + KE+ W +SNI AG + QIQ  V+  ++  L+ V+   D+K+QKEAAWA++N  +    +  +YL++  +   ++ +LS  +  ++ ++LDA+  +F  A+K+G+ E      E+ GG+D IE+LQ HE+  +Y  S +++
Sbjct:   13 RLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSP---LQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVR--LLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLI 492          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna4 (karyopherin (importin) alpha 4 [Source:MGI Symbol;Acc:MGI:1100848])

HSP 1 Score: 335.495 bits (859), Expect = 1.063e-108
Identity = 177/478 (37.03%), Postives = 285/478 (59.62%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR RN+  VE+RK K+++ L KRRN+  +D+ ++    S  +    +++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV    D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D +++  ++ ++  GD+ +QKEAAWA+SN+  S       YL+  NV      +L+  +  VV ++LD +  +   A+   Q E   N  E+ GG++ IE LQ HE+ DIY  +++I+
Sbjct:   15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICED----SDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED--QAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEII 481          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna4 (karyopherin (importin) alpha 4 [Source:MGI Symbol;Acc:MGI:1100848])

HSP 1 Score: 335.109 bits (858), Expect = 2.320e-107
Identity = 177/478 (37.03%), Postives = 285/478 (59.62%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR RN+  VE+RK K+++ L KRRN+  +D+ ++    S  +    +++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV    D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D +++  ++ ++  GD+ +QKEAAWA+SN+  S       YL+  NV      +L+  +  VV ++LD +  +   A+   Q E   N  E+ GG++ IE LQ HE+ DIY  +++I+
Sbjct:  117 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICED----SDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED--QAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEII 583          
BLAST of Importin subunit alpha vs. Ensembl Mouse
Match: Kpna3 (karyopherin (importin) alpha 3 [Source:MGI Symbol;Acc:MGI:1100863])

HSP 1 Score: 331.257 bits (848), Expect = 3.722e-107
Identity = 178/485 (36.70%), Postives = 289/485 (59.59%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+      +E++E S  +   + +++ +  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F +    +  LR+V W+I NLCR+K    P   + E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V+    +LLSH   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +LS  ++ VV ++LD ++ +   A    +        E+ GG++ IE LQ+HE+ DIY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP----QEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGD--EASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEII 481          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|P52171|IMA1_XENLA (Importin subunit alpha-1 OS=Xenopus laevis OX=8355 GN=kpna2 PE=1 SV=2)

HSP 1 Score: 355.91 bits (912), Expect = 7.314e-116
Identity = 182/483 (37.68%), Postives = 298/483 (61.70%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKE---IKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   +KN  KD   LRR R + SVE+RKAKK++Q+ KRRN+       E + +S ++N  +   +  +++ EI + + SG+    L +  + RK+LSK++NPP+ D  + G IP LV+ ++ + N  L FE+AWALTNIASG +  T++VV  GAIP F+ L+S     +SEQ++WAL NIAGD   YRD ++   +I  +   +    + L  LR++ W +SNLCR+K+   P S ++++LP++ ++M+   D     D  WA+SY  D  +D I+ ++   LV  LI  +   E  I+TPSLR +GN++ GTD+Q  AAI  GV+  +  LL H+ P + KE+ W LSNI AG   QIQ  + C ++ PL+D+++ GD+K+QKEA WAV+N  +    +  + L+   V   ++ +L+  ++  ++++LDA+  +F  A+K+G+ E LC+   E++GG++ IE+LQ H++  +Y  +  ++
Sbjct:   10 RMRKFKNKGKDTAELRRRRVEVSVELRKAKKDEQILKRRNVCFP----EELILSPEKNAMQSIQVPQLSLEEIVQGMNSGDNENELRSTQAARKMLSKERNPPLNDIIEAGLIPKLVEFLSYHNNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRDALISCNVIPPLLTLV-NPQTPLGYLRNITWTLSNLCRNKNPYPPMSAVLQILPVLTQLMLH-EDKDILSDTCWAMSYLTDGSNDRIDVVVKTGLVERLIQLMYSPELSILTPSLRTVGNIVTGTDKQTQAAIDAGVLSVLPQLLRHQKPSIQKEAAWALSNIAAGPAPQIQQMITCGLLSPLVDLLKKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAEKLGEQEKLCL-LVEELGGLEKIEALQTHDNRMVYHAALALI 485          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|P52170|IMA5_XENLA (Importin subunit alpha-5 OS=Xenopus laevis OX=8355 GN=kpna1 PE=1 SV=2)

HSP 1 Score: 352.443 bits (903), Expect = 1.579e-114
Identity = 179/480 (37.29%), Postives = 300/480 (62.50%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   +KN  KD   LRR R + SVE+RKAKK++Q+ KRRN+ + +    + E ++ ++V ++  +++ EI + + SG+    L    + RK+LS+++NPP+ D  + G IP LV+ ++ + N  L FE+AWALTNIASG +  T++VV  GAIP F+ L+S     +SEQ++WAL NIAGD   YRD ++   +I  +   ++   + L  LR++ W++SNLCR+K+   P S ++++LP++ ++M   +D     D  WA+SY  D  +D I+ ++   +V  LI  +   E  IVTPSLR +GN++ GTD+Q  AAI  GV+  +  LL H+ P + KE+ W +SNI AG   QIQ  + C ++ PL+D++  GD+K+QKEA WAV+N  +    +  + L+   V   ++ +L+  ++  ++++LDA+  +F  A+K+G+ E LC+   E++GG++ IE+LQ H++  +Y  +  ++
Sbjct:   10 RMRKFKNKGKDTAELRRRRVEVSVELRKAKKDEQILKRRNVCLPEELILSPEKNAMQSV-QVPPLSLEEIVQGMNSGDPENELRCTQAARKMLSRERNPPLNDIIEAGLIPKLVEFLSRHDNSTLQFEAAWALTNIASGTSDQTKSVVDGGAIPAFISLISSPHLHISEQAVWALGNIAGDGPLYRDALINCNVIPPLL-ALVNPQTPLGYLRNITWMLSNLCRNKNPYPPMSAVLQILPVLTQLMHH-DDKDILSDTCWAMSYLTDGSNDRIDVVVKTGIVDRLIQLMYSPELSIVTPSLRTVGNIVTGTDKQTQAAIDAGVLSVLPQLLRHQKPSIQKEAAWAISNIAAGPAPQIQQMITCGLLSPLVDLLNKGDFKAQKEAVWAVTNYTSGGTVEQVVQLVQCGVLEPLLNLLTIKDSKTILVILDAISNIFLAAEKLGEQEKLCL-LVEELGGLEKIEALQTHDNHMVYHAALALI 485          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|P52293|IMA1_MOUSE (Importin subunit alpha-1 OS=Mus musculus OX=10090 GN=Kpna2 PE=1 SV=2)

HSP 1 Score: 340.117 bits (871), Expect = 1.453e-109
Identity = 181/485 (37.32%), Postives = 288/485 (59.38%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNI--VIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLE--VLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R N +KN  KD   +RR R + +VE+RKAKK++Q+ KRRN+    DD +     +    N +   + ++ +I K + S N+   L A  + RKLLS++K PPI++  + G IP  V  +       + FESAWALTNIASG ++ T+AVV  GAIP F+ L++     +SEQ++WAL NIAGD + +RD+++KHG ID +   + +   S L    LR++ W +SNLCR+K+   P   + ++LP L+R  ++  ND     D  WA+SY  D  ++ I  ++   +VP L+  L   E  IVTP+LRAIGN++ GTDEQ    I  G +     LL++    + KE+ W +SNI AG + QIQ  V+  ++  L+ V+   D+K+QKEAAWA++N  +    +  +YL++  +   ++ +LS  +  ++ ++LDA+  +F  A+K+G+ E      E+ GG+D IE+LQ HE+  +Y  S +++
Sbjct:   13 RLNRFKNKGKDSTEMRRRRIEVNVELRKAKKDEQMLKRRNVSSFPDDATSP---LQENRNNQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVR--LLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLI 492          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|P52292|IMA1_HUMAN (Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1)

HSP 1 Score: 335.88 bits (860), Expect = 6.806e-108
Identity = 177/483 (36.65%), Postives = 286/483 (59.21%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLE--VLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R + +KN  KD   +RR R + +VE+RKAKK+DQ+ KRRN V     D    +    N +   + ++++I K + S N+   L A  + RKLLS++K PPI++  + G IP  V  +       + FESAWALTNIASG ++ T+AVV  GAIP F+ L++     +SEQ++WAL NIAGD + +RD+++K+G +D +   + +   S L    LR++ W +SNLCR+K+   P   + ++LP L+R  ++  +D     D  WA+SY  D  ++ I  ++   +VP L+  L   E  IVTP+LRAIGN++ GTDEQ    I  G +     LL++    + KE+ W +SNI AG + QIQ  V+  ++  L+ V+   D+K+QKEA WAV+N  +    +  +YL++  +   ++ +L+  +  +++++LDA+  +F  A+K+G+ E      E+ GG+D IE+LQ HE+  +Y  S  ++
Sbjct:   13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRN-VSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVR--LLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLI 492          

HSP 2 Score: 61.2326 bits (147), Expect = 1.465e-8
Identity = 61/280 (21.79%), Postives = 124/280 (44.29%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIA-----GTDEQADAAIK-CGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACV 1148
            CR   +K   PPI+   +   +P LV+++  +  E+L  ++ WA++ +  G N+    VVK G +P  VKL+  S   +   ++ A+ NI   + +   +++  G + V  + +     K  + +   W +SN+   +           L+P +  ++ +  D     +  WA++ Y      + I  L+   ++  L+  L  ++ +I+   L AI N+       G  E+    I+ CG +  +  L +H+N  + K S  ++    +  E + Q  V
Sbjct:  237 CR---NKNPAPPIDAVEQ--ILPTLVRLLHHDDPEVLA-DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTN--PKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKA-DFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVV 507          
BLAST of Importin subunit alpha vs. UniProt/SwissProt
Match: sp|O35343|IMA3_MOUSE (Importin subunit alpha-3 OS=Mus musculus OX=10090 GN=Kpna4 PE=1 SV=1)

HSP 1 Score: 335.495 bits (859), Expect = 7.433e-108
Identity = 177/478 (37.03%), Postives = 285/478 (59.62%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR RN+  VE+RK K+++ L KRRN+  +D+ ++    S  +    +++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV    D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D +++  ++ ++  GD+ +QKEAAWA+SN+  S       YL+  NV      +L+  +  VV ++LD +  +   A+   Q E   N  E+ GG++ IE LQ HE+ DIY  +++I+
Sbjct:   15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICED----SDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAED--QAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEII 481          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A5K4F0D4 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 388.267 bits (996), Expect = 6.656e-126
Identity = 195/481 (40.54%), Postives = 312/481 (64.86%), Query Frame = 3
Query:   60 INRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            + R  LYKN DKD E LRR R D SVE+RKAKK++QLQKRRNI++ +L DE   +  K+ V   + +N + + + ++S +      A   CRK LS+ KNPPI++FYK G + +L   ++   ++ L FE+AWALTNIASGD+ HT AVV +G +P  V+L+S S   ++EQS+WALSNIAGD +K+RD++++ G+++ V   + R W +  V+ +V W++SNLCR++    P + I +LLP++  ++    +     D  WALSYA D+ ++ I+ +I +  VP+L+  L      +++P+LRAIGN++ GTDEQ  A +  G++  V  LL+++   +VKE+CWV+SNI AG+  QI   +  +VM  +L+++  G++++QKEA W +SN  +        YLLN NV  A+  IL+ +E+ VV+++L+ +++L   +D+ GQLE      E  GG+D +E LQ+H +V +Y  ++D++
Sbjct:    1 MERSRLYKNKDKDAEELRRRRTDQSVELRKAKKDEQLQKRRNILLTEL-DETSPLKEKQ-VDTPEHVNYDAVIRDMQSNDRVIRFKAVQLCRKTLSRAKNPPIDEFYKRGAVEILGSSLSSTHDD-LVFEAAWALTNIASGDSSHTAAVVSSGTVPKLVRLLSHSAISIAEQSVWALSNIAGDGSKFRDIVIESGVVEPVLKLLDRVWKQPTVVSNVAWMLSNLCRNRDPPPPRAVIKKLLPVLNRLLQYEGNKNVVVDTAWALSYASDAVNEFIDDIIESGCVPLLLRLLASSSANLISPALRAIGNLVIGTDEQTQAILDAGLLTYVPALLNNEKSTVVKEACWVVSNITAGSVDQIDMVISHNVMPCILEILYKGEFRTQKEACWVISNYISGGTPAQCAYLLNQNVLKALCNILTVSESKVVLMVLEGIKKLLEISDQYGQLEPACIELETCGGLDKLEGLQDHSNVQVYQIAYDLI 478          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A0X3PDU1 (Importin subunit alpha OS=Schistocephalus solidus OX=70667 GN=IMA1 PE=3 SV=1)

HSP 1 Score: 386.341 bits (991), Expect = 3.440e-125
Identity = 193/484 (39.88%), Postives = 305/484 (63.02%), Query Frame = 3
Query:   60 INRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKS-GNITQ--MLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            ++R  LYKN  KD E LRR R D SVE+RKAKK++QLQKRRN++      E ++ +S     +I    +    K++   GN +Q   L A  +CRK LS+ KNPPI++F+  G + LL   + D K++ + FE+AWALTNIASG++ HT+ VV +GA P  ++L+S    +++EQ IWAL NIAGD    RDM+++ G+++     + R W    V+ ++ W++SNLCR+K+ + P   I  LLP++++++     V    D  WALSYA DS +D IN ++A++  P LI  L      +++P+LRAIGN++ G D+Q    +  GV+  +  LL+     ++KESCW+LSN+ AG+  QIQ+ +D  ++  +L++M   ++K QKEA W +SNM N  + + + YLLN NV  A+  +L+ ++  V++L+L+A+R LF  A + GQLE C  + E  GG+D +E LQ+H +  +Y  ++D++
Sbjct:    1 MDRSRLYKNKSKDNEELRRRRIDQSVELRKAKKDEQLQKRRNVL------EGVDETSPLKETQISGTEVINYDKIVSDMGNRSQEVQLQAIQTCRKTLSRAKNPPIDEFFNRGVVRLLTAAL-DAKSDAIVFEAAWALTNIASGESHHTQGVVDSGASPKLIRLLSHKDIRIAEQCIWALGNIAGDGTSQRDMLIRMGVVEPTLRLLDRAWDSPGVVSNIAWMLSNLCRNKNPHPPRETIQRLLPILKKLLGYSKSVDVVVDAAWALSYASDSANDFINDILASDCAPTLIKLLGSGTPGLISPALRAIGNLVLGDDDQTQVIVDAGVLAYMPDLLNSDRSSIIKESCWMLSNVTAGSIPQIQSVIDAKIIPRVLELMLKEEFKIQKEACWVISNMINGGSPEQRAYLLNQNVLAALSKLLTVSDVRVLVLVLEAIRRLFETAHEFGQLEQCCLSLEACGGLDSLEQLQDHNNEQVYQAAYDMI 477          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A0R3X6M7 (Importin subunit alpha OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS9153 PE=3 SV=1)

HSP 1 Score: 379.022 bits (972), Expect = 3.214e-122
Identity = 194/486 (39.92%), Postives = 302/486 (62.14%), Query Frame = 3
Query:   60 INRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVID-----DLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +NR  LYKN  KD + LRR R D SVE+RKAKKE QLQKRRN+V++      L D + E SS          + +EI   +KS ++   L A  +CRK LSK +NPPI++F++ G   +LVK++ D++++ + FE+AWALTNIASGD+ HT  VV+AGA+P  ++L+  S  +++EQ IWAL N+AGD  K+RDM+++ G+++     + R W    V+ +V W++SNLCR+K+ + P S + ELLP    +++  +      D  WALSYA D     I+ ++ +  V +L+ +L      +V+P+LR IGN+I GTD+Q    I CGV+  V  LL+     +VKE+CW+LSNI AGN  QIQ  +D  V+  +LD+MR  D+K QKEA W ++N+    + +   +LLN  V  ++  +L+  +  ++  +L  ++++F  A+   QLE C  A E  G +  +E LQ+H++ +IY +++D +
Sbjct:    3 MNRSRLYKNTGKDNDELRRRRTDQSVELRKAKKEQQLQKRRNVVVELEKTSPLKDHS-ETSSPPP-------SYDEIVADMKSSDVNVALAATQTCRKTLSKLRNPPIDEFFERGAHKILVKLL-DSESDEMIFEAAWALTNIASGDSYHTGGVVEAGAVPKLIRLLHHSDVRIAEQCIWALGNVAGDGTKHRDMVIRQGVVEPSLELLRRSWDSPNVVSNVAWMLSNLCRNKNPDPPLSTVRELLPAFARLLMYPHSTEAVVDTAWALSYASDCGGAFIDEILKSGCVYILVRHLGSDFSNLVSPALRTIGNLILGTDQQTQDTIDCGVMQYVPKLLNSSRSNVVKETCWMLSNITAGNLDQIQTVLDAGVIPKILDIMREADFKVQKEACWVINNIVVGGSPEQLAFLLNLGVLDSLSKMLTVTDPGMIRQVLATLKKIFETAEAYNQLENCCLALERCGALGTLEKLQDHQNEEIYLEAYDFI 479          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A0R3UJ80 (Importin subunit alpha OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS7546 PE=3 SV=1)

HSP 1 Score: 378.637 bits (971), Expect = 4.776e-122
Identity = 193/482 (40.04%), Postives = 299/482 (62.03%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDI--NINEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMT-DNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R  LYKN  KD E LRR R D SVE+RKAKK+ QLQKRRN++ D      ++ +S+    ++K    N ++I   ++S N    L+A   CRKLLS+ KNPPI++F++ G + +LV+ +  D  +  L FE+AWALTNIASG++ HT+ VV++GA P  + L++    +V+EQ IWAL NIAGD   YRDM++K G +      + R W    V+ ++ W++SNLCR+K+ N P   I+ LLP+ + ++          D  WALSYA D   + I+ ++ +  +PVL+  L      +V+P+LRA+GN+I G DEQ    +  GV+     LL    P +VKE+CW+LSNI AGN +QIQA VD +++  ++ ++   ++K QKEA W +SN+ N  + + + YLLNN    A+  +L+ ++  V+ L+L+ ++++F  A + GQLE C  A E  GG++ IE LQ+H + ++Y  ++D +
Sbjct:    3 RSRLYKNSGKDNEELRRRRIDQSVELRKAKKDQQLQKRRNVLRD------VQETSQVESYDLKSAPANYDQIIFEMESPNTLVRLNATRMCRKLLSRAKNPPIDEFFERGAVKVLVRALDFDPSSNELVFEAAWALTNIASGESHHTQGVVESGAAPKLIHLLNHEDVRVAEQCIWALGNIAGDGCSYRDMLIKLGAVPPALQLLERAWDSAGVVSNIAWMLSNLCRNKNPNPPRQTILSLLPVFKRLLEYPLSQEVIVDTAWALSYASDCAGEFIDDILQSGCIPVLVRLLGSNSPNLVSPALRAVGNLILGDDEQTQVVVDSGVLQYAQGLLDFDRPSVVKEACWMLSNITAGNLTQIQAVVDANLVPRIIKLVEEAEFKIQKEACWVISNIVNGGSPEQRAYLLNNGALEALSKLLNVSDARVLKLVLETIKKMFETAKQFGQLEPCCLALELCGGLNSIEQLQDHTNDEVYRIAYDFI 478          
BLAST of Importin subunit alpha vs. TrEMBL
Match: A0A267FVN3 (IBB domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007573g1 PE=4 SV=1)

HSP 1 Score: 379.793 bits (974), Expect = 7.351e-122
Identity = 209/525 (39.81%), Postives = 316/525 (60.19%), Query Frame = 3
Query:   27 ILNLFSR*MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVI----DD----LSDENIEVSSKENVKEIKDIN-------INEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLE---------------VLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEIND--VACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQL-ELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +++  SR  SE  R  LYKN DKD E LRR RND SVE+RKA K DQ+ KRRNI +    DD    L D   + S K  +  ++D N       I++I K +KSG+      A  +CR+ LSK+++PPI++F   G +P LV  +T   N  + FE+AWALTNIASG+ +HT AVV AGA+   ++L++     V+EQ++WAL NIAGD ++ RD  +K GI+  +   + R                     +L +  WL+SNLCR+K+   P+S ++ELLP +  ++   +   V  TC   WALSY  D+ +D+I  +IA+ ++P L+A L+  E  IVTP+LR IGN++ GTD+Q D A+  G +     LL H  P +VKE+ W LSN++AG++ QIQ  +D +++ PL+ ++ NGD+K++KEA WA++NM    ++    YL N NV  A+  +LS  E  +V ++++++  L + A K  Q  ++CI A E  GG+D +E+LQEHE+  +Y  S  ++
Sbjct:   15 VMDSTSRTPSE--RSRLYKNKDKDGEELRRRRNDASVELRKASKTDQMMKRRNIDLAAGDDDEDVALGDGQQQASGKV-LSPLRDANNVLANASIDDICKAMKSGSPADQFAAIQACRRALSKERHPPIDEFVNRGVLPELVVALTKPANHQVVFEAAWALTNIASGEAQHTRAVVNAGALQPLIELLNSEHLNVAEQAVWALGNIAGDGSELRDRAIKAGIVQPLLRLLQRVSRDSAIAASSSSSGSDNSVSLLGNCAWLVSNLCRNKNPPPPASAVLELLPAMAALLQAPHKEVVQDTC---WALSYVTDAVNDLIGQVIASGVLPTLVALLDHTEAAIVTPALRTIGNIVTGTDQQTDTALAAGFLPKCHRLLLHNKPNIVKEAAWALSNVLAGSQPQIQQVIDNNLIPPLIGIVINGDFKAKKEATWALTNMVTGGDEAQISYLANQNVVPALCEMLSVQEAKIVCIVMESLTALLSLAKKYNQADDMCI-AIEGCGGLDKLEALQEHENPRVYEMSLQMI 532          

HSP 2 Score: 61.2326 bits (147), Expect = 4.543e-6
Identity = 57/269 (21.19%), Postives = 115/269 (42.75%), Query Frame = 3
Query:  342 LSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANE-LVPVLIANLNRQECEIV---TPSLRAIGNVIAGTDEQADAAIK---CGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNE 1127
            L + KNPP         +P +  ++     E++  ++ WAL+ +    N     V+ +G +P  V L+  +   +   ++  + NI   + +  D  +  G +      +L   +K  +++   W +SN+               L+P +  I++   D     +  WAL+  +   D+   + +AN+ +VP L   L+ QE +IV     SL A+ ++    ++  D  I    CG +  +  L  H+NPR+ + S  ++      +E
Sbjct:  276 LCRNKNPPPPASAVLELLPAMAALLQAPHKEVVQ-DTCWALSYVTDAVNDLIGQVIASGVLPTLVALLDHTEAAIVTPALRTIGNIVTGTDQQTDTALAAGFLPKCHRLLLH--NKPNIVKEAAWALSNVLAGSQPQIQQVIDNNLIPPLIGIVIN-GDFKAKKEATWALTNMVTGGDEAQISYLANQNVVPALCEMLSVQEAKIVCIVMESLTALLSLAKKYNQADDMCIAIEGCGGLDKLEALQEHENPRVYEMSLQMIEEFFGNDE 540          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna2 (importin subunit alpha-1-like [Source:NCBI gene;Acc:103025752])

HSP 1 Score: 347.051 bits (889), Expect = 3.021e-113
Identity = 186/485 (38.35%), Postives = 288/485 (59.38%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDE-NIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI----LRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   +KN  KD   LRR R + +VE+RKAKK+DQ+ KRRN+ +  L DE    +  K    + +   + EI   + S N+     A  + RKLLS++++PPI+     G IP  V  +  +   I  FE+AWALTNIASG +  T AVV+ GAIP F+ L+S     +SEQ++WAL NIAGD + YRD ++KHG I  + + +    L  ++    LR++ W +SNLCR+K+   P   + ++LP I  ++   ND     D  WA+SY  D  +D I  ++   +VP L+  L   E  IVTPSLR+IGN++ GTDEQ  A +  G +    +LL H    + KE+ W +SNI AG ++QIQ  ++  ++  L++V++ GDYK+QKEA WAV+N  +    +  +YL+  NV   ++ +LS  ++  ++++LDA+  +F   +KIG+ + LC+   E+ GG+D IE+LQ HE+  +Y  S +++
Sbjct:   11 RLTQFKNKGKDTTELRRRRIEVNVELRKAKKDDQIMKRRNVAV--LPDEVTSPLQEKSQNCQAQHWTVEEIVNGVNSNNLETQTQATQAARKLLSRERHPPIDRIISAGLIPRFVGFLGIDSPPI-QFEAAWALTNIASGTSDQTAAVVEGGAIPAFIGLISSPHPHISEQAVWALGNIAGDGSSYRDKVIKHGAIPPLLSLLAVPDLSVFAS-GYLRNLTWTLSNLCRNKNPAPPLEAVRQILPTIIRLLHH-NDKEVLADTCWAVSYLTDGPNDRIEVVVQTGVVPRLVQLLGSGELSIVTPSLRSIGNIVTGTDEQTQAVLDSGALPMFTNLLRHHKNNIQKEAAWAMSNITAGKDTQIQEVINAGLVPHLVEVLKRGDYKTQKEAVWAVTNFTSGGTIEQVIYLVQANVLEPLLNLLSVKDSKTILVILDAISNIFLAGEKIGETDKLCL-MIEECGGLDKIEALQTHENEMVYKASLNLI 489          

HSP 2 Score: 65.4698 bits (158), Expect = 6.234e-11
Identity = 66/285 (23.16%), Postives = 133/285 (46.67%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS--YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNV------IAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDV 1160
            CR   +K   PP+E   +   +P +++++  N  E+L  ++ WA++ +  G N   E VV+ G +P  V+L+      +   S+ ++ NI   + +    ++  G + +  N +LR   K  + +   W +SN+   K T         L+P + E++ +  D     +  WA++   +  + + +I  + AN L P L+  L+ ++ + +   L AI N+      I  TD+      +CG +  +  L +H+N  + K S  ++    +G E + + CV  +V
Sbjct:  234 CR---NKNPAPPLEAVRQ--ILPTIIRLLHHNDKEVLA-DTCWAVSYLTDGPNDRIEVVVQTGVVPRLVQLLGSGELSIVTPSLRSIGNIVTGTDEQTQAVLDSGALPMFTN-LLRH-HKNNIQKEAAWAMSNITAGKDTQIQEVINAGLVPHLVEVL-KRGDYKTQKEAVWAVTNFTSGGTIEQVIYLVQANVLEP-LLNLLSVKDSKTILVILDAISNIFLAGEKIGETDKLCLMIEECGGLDKIEALQTHENEMVYKASLNLIEKYFSGEEEEDE-CVAPEV 507          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: KPNA2 (karyopherin subunit alpha 2 [Source:NCBI gene;Acc:103045972])

HSP 1 Score: 339.732 bits (870), Expect = 2.314e-110
Identity = 189/488 (38.73%), Postives = 289/488 (59.22%), Query Frame = 3
Query:   60 INRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNI--VIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI----LRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE-LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            + R N +KN  KD   LRR R + SVE+RKAKK+DQ+ KRRN+    DD S    E     N +  +  ++ EI   + S ++   L A  + RKLLS++K+PPI+   + G I  LV  +   +   + FE+AWALTNIASG +  T AVV+AGAIP F+ L++     VSEQ+IWAL NIAGD + YRD ++KHG I+ +   +    L  ++    LR+V W +SNLCR+K+   P   + ++LP    +++   D     D  WA+SY  D  ++ I  ++  ++VP L+  L   +  IVTPSLRAIGN++ GTDEQ    +  G +     LL H    + KE+ W LSNI AG +SQIQ  +   ++  L++V++ GD+K+QKEA WA++N  +    +   YL+ + V   ++ +L   ++  V+++LDAV  +F  ADK+G+ E LC+   E+ GG+D IE+LQ HE+  +Y  + +++
Sbjct:    9 VARLNQFKNKGKDANELRRRRIEVSVELRKAKKDDQILKRRNVSCFPDDASSPFYE--QNHNAQSSQHWSVEEIVCGVNSQSLDHQLQATQAARKLLSREKHPPIDSIVEAGLISKLVNFLALFQCPPIQFEAAWALTNIASGTSDQTRAVVEAGAIPAFISLIASPHPHVSEQAIWALGNIAGDGSTYRDKVIKHGAIEPLLALLSVPNLSMYTP-AYLRNVTWTLSNLCRNKNPAPPLLAVQQMLP-ALLLLLHHEDPEVLADTCWAVSYLTDGPNERIEVVVQADIVPRLVQLLACGDITIVTPSLRAIGNIVTGTDEQTQKVLNAGALAVFPTLLCHPKNNIQKEAAWALSNITAGRDSQIQEVISAGLVPILVEVLQQGDFKTQKEAVWAITNYTSGGTVQQVAYLVQSGVLAPLLDLLFVKDSKTVLVILDAVLNIFMAADKMGETEKLCL-MVEECGGLDNIEALQTHENEMVYKAALNLI 491          

HSP 2 Score: 57.7658 bits (138), Expect = 1.651e-8
Identity = 54/276 (19.57%), Postives = 122/276 (44.20%), Query Frame = 3
Query:  342 LSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADA------AIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACV 1148
            L + KNP          +P L+ ++     E+L  ++ WA++ +  G N+  E VV+A  +P  V+L++C    +   S+ A+ NI   + +    ++  G + V    +     K  + +   W +SN+   + +         L+P++ E++ +  D     +  WA++ Y        +  L+ + ++  L+  L  ++ + V   L A+ N+    D+  +         +CG + ++  L +H+N  + K +  ++    +G E + ++ V
Sbjct:  235 LCRNKNPAPPLLAVQQMLPALLLLLHHEDPEVLA-DTCWAVSYLTDGPNERIEVVVQADIVPRLVQLLACGDITIVTPSLRAIGNIVTGTDEQTQKVLNAGALAVFPTLLCH--PKNNIQKEAAWALSNITAGRDSQIQEVISAGLVPILVEVLQQ-GDFKTQKEAVWAITNYTSGGTVQQVAYLVQSGVLAPLLDLLFVKDSKTVLVILDAVLNIFMAADKMGETEKLCLMVEECGGLDNIEALQTHENEMVYKAALNLIEKYFSGEEEEDESVV 506          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna3 (karyopherin subunit alpha 3 [Source:NCBI gene;Acc:103046682])

HSP 1 Score: 335.109 bits (858), Expect = 1.140e-108
Identity = 179/486 (36.83%), Postives = 292/486 (60.08%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDD-LSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+  D+ L D +++   K      +++ ++ I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVVK+ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F +    +  LR+V W+I NLCR+K    P   + E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V+    +LL+H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +LS  ++ VV ++LD ++ +   A +  +        E+ GG++ IE+LQ+HE+ DIY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQDESLEDSDVDADFKG-----QNVTLDAILQNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGE--EASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEII 481          

HSP 2 Score: 66.2402 bits (160), Expect = 4.324e-11
Identity = 57/271 (21.03%), Postives = 122/271 (45.02%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVI--AGTDEQADAAI--KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNE 1127
            CR   +K   PP+E   +   +P L  ++      IL  ++ WAL+ +  G N+  + V+ +G +P  V L+S    +V   ++ A+ NI   + +   +++   ++    N +     K ++ +   W +SN+         +     L+P+I   + +  D     +  WA+S   I  R D +  L+   ++P     L+ ++ ++V   L  + N++  AG +    A I  +CG +  + +L  H+N  + K +  ++    +G++
Sbjct:  228 CR---NKDPPPPMETVQE--ILPALCVLIYHTDINILV-DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLTH--PKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAK-GDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDD 489          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna4 (karyopherin subunit alpha 4 [Source:NCBI gene;Acc:103046926])

HSP 1 Score: 329.331 bits (843), Expect = 1.976e-106
Identity = 176/478 (36.82%), Postives = 282/478 (59.00%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR R +  VE+RK K+++ L KRRN+  +D+ D+    S  +     ++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV    D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D +++  ++ ++  GD+ +QKEAAWA+SN+  S       YL+   V      +L+  +  VV ++LD +  +   AD   + E   N  E+ GG++ IE LQ HE+ DIY  +++I+
Sbjct:   15 FKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDICDD----SDVDGDFRTQNTSLEAIVQNATSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALGHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIILLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADD--EAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEII 481          
BLAST of Importin subunit alpha vs. Ensembl Cavefish
Match: kpna3 (karyopherin subunit alpha 3 [Source:NCBI gene;Acc:103046682])

HSP 1 Score: 325.094 bits (832), Expect = 7.907e-105
Identity = 180/489 (36.81%), Postives = 289/489 (59.10%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDD-LSDENIEVSSKE-NVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVAC--TCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+  D+ L D +++   K   V ++   + +       S N    L A  + RKLLS  +NPPI+D  K+G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVVK+ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F +    +  LR+V W+I NLCR+K    P   + E    +R + V + D+ C    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V+    +LL+H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +LS  ++ VV ++LD ++ +   A +  +        E+ GG++ IE+LQ+HE+ DIY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQDESLEDSDVDADFKGVRVSQLFSHSFHNA----TSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQE----VRGVCVCVKDLNCCILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGE--EASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEII 482          

HSP 2 Score: 64.6994 bits (156), Expect = 1.185e-10
Identity = 56/271 (20.66%), Postives = 122/271 (45.02%), Query Frame = 3
Query:  330 CRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS-YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVI--AGTDEQADAAI--KCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNE 1127
            CR   +K   PP+E   +   + + VK +    N  +  ++ WAL+ +  G N+  + V+ +G +P  V L+S    +V   ++ A+ NI   + +   +++   ++    N +     K ++ +   W +SN+         +     L+P+I   + +  D     +  WA+S   I  R D +  L+   ++P     L+ ++ ++V   L  + N++  AG +    A I  +CG +  + +L  H+N  + K +  ++    +G++
Sbjct:  230 CR---NKDPPPPMETVQEVRGVCVCVKDL----NCCILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLTH--PKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAK-GDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEIIEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDD 490          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: kpna7 (karyopherin alpha 7 (importin alpha 8) [Source:ZFIN;Acc:ZDB-GENE-040426-2023])

HSP 1 Score: 337.035 bits (863), Expect = 2.728e-110
Identity = 170/469 (36.25%), Postives = 278/469 (59.28%), Query Frame = 3
Query:  108 LRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI-LRFWSKLEV--LRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            LR++R D  +E+RKA+K+DQ+ KRRN+   D    +     ++N ++ + +++ EI + + S      L +    RKLLS++++PP+ +    G IP  V+ +       + FE+AWALTNIASG ++ T+AVV  GA+P FV L+S     +SEQ++WAL NIAGD    RD+++K+G ++ +   + +   S L V  LR++ W ISNLCR+K    P   ++ LLP L+R  ++   D     D  WALSY  D  +D I  ++A  +VP L   L   E  ++TP+LR +GN++ GTD+Q  A I  GV+    +LL H+   + KE+ W LSNI AG+  QI A +   ++ PL++V+  G++K+Q+EA WAV+N+ +     H +Y++       ++ +L   ++  V+++LDA+  +F   DK+GQ +      E++GG+D IE LQ HE+  +Y  + +I+
Sbjct:    1 LRQHRKDLCLELRKARKDDQILKRRNVAAMDDEPTSPLQEKQQNGQKAQQMSLEEIVRGVSSNESDVQLQSTQGARKLLSRERHPPLNEIISAGLIPRFVQFLGHEDCSQIQFEAAWALTNIASGTSEQTKAVVDGGAVPAFVALLSSPHAHISEQAVWALGNIAGDGPVLRDLVIKYGAVEPLLALMAMPDLSMLSVSYLRNLTWTISNLCRNKKPPPPEEAVLMLLPALVR--LLHHEDREVQTDATWALSYLSDGPNDRIEMVVAAGVVPRLAQLLASPELTVLTPALRTVGNIVTGTDQQTQAVINTGVLPVFQNLLRHQRSNVQKEAAWALSNITAGHAEQINAVITAGLIPPLVEVLHKGEFKAQREAVWAVTNLTSGGTVDHIVYVVQVGAMEPLLSLLEVKDSSTVLIILDAITNIFQAGDKVGQTDKLCMMVEELGGLDKIEHLQSHENEAVYKAALNII 467          

HSP 2 Score: 63.1586 bits (152), Expect = 6.532e-11
Identity = 59/277 (21.30%), Postives = 125/277 (45.13%), Query Frame = 3
Query:  342 LSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALS--YAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVG------HLLSHKNPRLVKESCWVLSNIIAGNESQIQACV 1148
            L + K PP  +      +P LV+++     E+ T ++ WAL+ ++ G N   E VV AG +P   +L++     V   ++  + NI   + +    ++  G++ V +N +LR   +  V +   W +SN+    +    +     L+P + E++ +  +     +  WA++   +  + D I+  +    + P L++ L  ++   V   L AI N+    D+       C ++  +G      HL SH+N  + K +  ++    + ++S+ +  V
Sbjct:  211 LCRNKKPPPPEEAVLMLLPALVRLLHHEDREVQT-DATWALSYLSDGPNDRIEMVVAAGVVPRLAQLLASPELTVLTPALRTVGNIVTGTDQQTQAVINTGVLPVFQN-LLRH-QRSNVQKEAAWALSNITAGHAEQINAVITAGLIPPLVEVLHK-GEFKAQREAVWAVTNLTSGGTVDHIVYVVQVGAMEP-LLSLLEVKDSSTVLIILDAITNIFQAGDKVGQTDKLCMMVEELGGLDKIEHLQSHENEAVYKAALNIIDKYFSEDDSEAENLV 482          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: kpna4 (karyopherin alpha 4 (importin alpha 3) [Source:ZFIN;Acc:ZDB-GENE-030131-5584])

HSP 1 Score: 324.709 bits (831), Expect = 2.695e-105
Identity = 176/489 (35.99%), Postives = 289/489 (59.10%), Query Frame = 3
Query:   51 MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNI--AGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            ++E +R   +KN  +D E++RR RN+ ++E+RK K+++ L KRRN+  +++ DE       +    +++ ++  I +   S N    L A  + RKLLS  +NPPI+D   +G +P+LV+ +    N  L FE+AWALTNIASG +  T+AVVK+ A+P+F+KL+      V EQ++WAL NI  AGD  + RD ++  G++      +L F +    +  LR+V W+I NLCR+K    P   I E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       YL+  NV      +L+  +  VV ++LD +  +   A +  ++E   +  E+ GG++ IE+LQ+HE+ DIY  +++I+
Sbjct:    7 LAENHRIKSFKNKGRDAETMRRQRNEVTIELRKNKRDEHLLKRRNVPHEEILDE----LDFDGDFRLQNASLEAIVQNAASDNPNVQLSAVQAARKLLSSDRNPPIDDLINSGILPILVQCLEREDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLKLLHSPHQNVCEQAVWALGNIIAAGDGPQCRDYVISLGVV----KPLLAFINPAIPITFLRNVTWVIVNLCRNKDPPPPMETIQEILPALC-VLIHHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHAKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHHLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVRENVIPPFCALLAVKDPQVVQVVLDGLNNILKMAGE--EVETIASVIEECGGLEKIEALQQHENEDIYKLAYEII 484          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005568.1 (pep scaffold:Pmarinus_7.0:GL477092:38612:43101:1 gene:ENSPMAG00000005012.1 transcript:ENSPMAT00000005568.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 209.149 bits (531), Expect = 3.390e-62
Identity = 129/395 (32.66%), Postives = 208/395 (52.66%), Query Frame = 3
Query:  333 RKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHG----IIDVVKNC-ILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            RK+LS++K+PP  D    G +P  V  +  +   +L FE+AWALTNIASG  + T  VV AGA+P  V+L+S     +SEQ++WAL NIAGD A++RD++V  G    ++ +++NC I  F   + +LR++ W +SNLCR+K+     + ++ LLP +  ++    D     D  WALSY  D  ++ I+ + A  + P L+  L      +VTP LRAIGN++ GTDEQ    +K G +     LL H    + KE+ W +SN+ AG   QI+  +   ++  L+ V+            W    + + A    +      + +     +L+  +   V+     VR     A+KIG++E      E+  G++ +E LQ HE+  IY  +  ++
Sbjct:    1 RKMLSREKHPPFNDIIAAGLVPEFVACLDRDDCPLLQFEAAWALTNIASGTGEQTAIVVAAGAVPALVRLVSSPHSHISEQAVWALGNIAGDGAEHRDLVVNSGAVGPLVALLENCNIDEF--HVGLLRNLTWTLSNLCRNKNPAPSVTTVLMLLPTMVRLLHHA-DHEIEADAAWALSYLTDGTNERIHLVQAQGVTPRLVQLLGCDVPAVVTPCLRAIGNMVTGTDEQTQVVLKAGALDMFPMLLRHPKSNIQKEATWAVSNVAAGPIDQIEQIIAAGLVPHLIHVLDKLGQSQYLAPTWVCPIITSDALPSFRFVKQQLDTY--FKNLLARKDRTPVL-----VRCGAKAAEKIGEVENMTLMVEESEGLENLEMLQMHENETIYKTALALL 385          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: kpna6 (karyopherin alpha 6 (importin alpha 7) [Source:ZFIN;Acc:ZDB-GENE-130530-626])

HSP 1 Score: 101.679 bits (252), Expect = 3.086e-25
Identity = 45/158 (28.48%), Postives = 93/158 (58.86%), Query Frame = 3
Query:  927 NLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE 1400
            +L   + ++V+P+LRA+GN++ G D Q    + C  +  + HLLS+    + KE+CW +SNI AG+ +QIQA +D ++   L+++++  +++++KEAAWA++N  +    +   +L+       +  +L+  +  +V + L+ +  +     K+G+ E
Sbjct:   16 SLRHTDVKVVSPALRAVGNIVTGDDMQTQVILNCSALPCLLHLLSNPKESIKKEACWTISNITAGSRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRFLVEQGCIKPLCDLLTVMDAKIVQVALNGLENIL----KLGEQE 169          
BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008519.1 (pep scaffold:Pmarinus_7.0:GL480915:29739:34392:1 gene:ENSPMAG00000007713.1 transcript:ENSPMAT00000008519.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 101.293 bits (251), Expect = 5.117e-25
Identity = 69/176 (39.20%), Postives = 101/176 (57.39%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVI--DDLS-DENIEVSSKENV--KEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIED-FYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQ 575
            R   YKN   + + +RR R +  +++RK K+E QL KRRN+ I  +D+S D  I+  S       E   I I E+ +++ S +    L A    RKLLSK+ NPPI++     G +P  V+ +   +N  L FE+AWALTNIASG +  T  V+ AGA+P+F+ L+S   + V EQ
Sbjct:   18 RMRSYKNKALNPQEMRRRREEEGIQLRKQKREQQLFKRRNVDIPNEDVSMDNGIQDPSVTTTIPGEFSVITI-EMLQMIFSDDPEHQLAATQKFRKLLSKEPNPPIDEVIVSPGVVPRFVEFLKRRENCTLQFEAAWALTNIASGTSTQTRVVITAGAVPIFITLLSSDFEDVQEQ 192          
BLAST of Importin subunit alpha vs. Ensembl Yeast
Match: SRP1 (Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation [Source:SGD;Acc:S000005133])

HSP 1 Score: 285.419 bits (729), Expect = 3.283e-90
Identity = 170/500 (34.00%), Postives = 282/500 (56.40%), Query Frame = 3
Query:   42 SR*MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIV--IDDL-SDENIEVSSKENVKEIKDININEIPKL---LKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKL--YLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTC--ADKIGQ-LELCINA--FEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            S+ + E  R N    G    + LRR R+   VE+RKAK+++ L KRRN +   D   SDE  E S   + +    +   E+P++   L S ++ + L A    R++LS++  PPI+   + G +P LV+ M +N+ E+L  E+AWALTNIASG +  T+ VV A A+P+F++L+   + +V EQ+IWAL N+AGDS  YRD +++   ++ +    L   +K  ++R   W +SNLCR K      S + + LP + +++  + D     D  WA+SY  D   + I A+I   +   L+  L+ +   + TP+LRA+GN++ G D Q    I  GV+ ++  LLS     + KE+CW +SNI AGN  QIQA +D +++ PL+ ++   +YK++KEA WA+SN ++    +  +  YL++      +  +L   +N ++ + LDA+  +     ADK  + L +  NA   E  GG++ I + Q++E+  IY K++ I+
Sbjct:   10 SKFVPEYRRTNFKNKGRFSADELRRRRDTQQVELRKAKRDEALAKRRNFIPPTDGADSDEEDESSVSADQQFYSQLQ-QELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILG--LFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSM-DTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKII 505          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO30648 (Importin subunit alpha [Source:UniProtKB/TrEMBL;Acc:A7T055])

HSP 1 Score: 328.176 bits (840), Expect = 2.025e-106
Identity = 181/489 (37.01%), Postives = 296/489 (60.53%), Query Frame = 3
Query:   51 MSE-INRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKL---LKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKI-GQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            M+E I+R   +KN  KD   +RR RN+ SV++RK+K+++ + KRRNI   D +    E +++ +V     I I  +P +   L+SG+   M  +  S RK+LSK+K+PPI+D    G IP+LVK++      +L FE+AWALTNIASG ++ T+AV + GA+P+FVKL+S   D V+EQ++WAL NIAGD    R+ ++  G +  +   +++  + ++ LR+V W +SNLCR+K+     + + ++LP I  +++  +D     D  WALSY  D  ++ I  ++ + +VP L+  L   E  ++TP+LRAIGN++ G D+Q  A I  G +     LL+HK   ++KE+ W +SN+ AG   QIQA +D  ++  ++D++R GD+K++KEA W ++N  + AN     YLL+ +V   +   L   +   + +LLD ++ L   A KI G L+  ++  E+  GID +E LQE+ +  IY K+  ++
Sbjct:    1 MAENISRIQAFKNKGKDSSEMRRRRNEVSVQLRKSKRDENVLKRRNITDVDSTSPLKEHNNQHSVP----IQILPLPVVVGNLQSGDDNLMFTSVQSVRKMLSKEKSPPIDDVINAGLIPMLVKLLDRFDLPLLQFEAAWALTNIASGTSEQTKAVQEGGAVPMFVKLLSSVHDNVAEQAVWALGNIAGDGPLMRNTVIACGALGPLL-ALIKPSTSIQFLRNVTWTLSNLCRNKNPPPDVTAVQQVLPAIARLILS-DDKEVLADTCWALSYLTDGVNERIQLVLDSGVVPKLVELLGYPEVNVLTPALRAIGNIVTGRDDQTQAVIDTGALFYFRALLTHKKSNIIKEAAWAISNVTAGTAQQIQAVMDSGLVPLIVDILRRGDFKARKEAIWVITNYCSGANPDQVKYLLHCDVIPPLCEQLKIQDQKDIQILLDGLKSLLASASKIEGMLDDTLDKIEESEGIDHLEKLQENGNKQIYLKAKGLI 483          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO38337 (Importin subunit alpha [Source:UniProtKB/TrEMBL;Acc:A7SD78])

HSP 1 Score: 286.189 bits (731), Expect = 3.239e-90
Identity = 162/484 (33.47%), Postives = 270/484 (55.79%), Query Frame = 3
Query:   66 RRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDINI-NEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAF----EDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R   YKN   D   +RR R +  V++RKAK+E+Q+ KRRN+ +   S    E+        + +  +  ++ + + S ++   L A    RK+LSK+ NPPI+D  K G IP  V+ +    N  L FE+AWALTNIASG +  T   V AGA+P F+KL+    ++V EQ++WAL NIAGDSA  RD ++  G++    N + +  ++L + R++ W +SNLCR +      + +   LPL+  ++    D     D  WALSY +D  ++ I A+I + +   L+  L+  +  +V+ +LRA+GN++ G D Q    + C  + ++ HLLS     + KE+CW +SNI AGN  QIQA +D +++  L+DV+   ++K++KEAAWA++N  +    +   Y+++      +  +L+     +V + L+A+  +     +  +     N +    E+  G+D +E LQ H++  IY KSF+I+
Sbjct:    8 RIKAYKNKSLDVSEMRRRREEEGVQLRKAKREEQMFKRRNVEVTRTSSTGSELEELLTSDYMAEGPLFQDMVQAIISDDVEMQLAATQRFRKILSKEPNPPIDDVIKCGVIPKFVEFLQREDNSALQFEAAWALTNIASGTSMQTRETVNAGAVPCFIKLLESPKEEVQEQAVWALGNIAGDSADCRDYVLNCGVLTPFLNLLTKS-TRLSMTRNLVWALSNLCRGRHPPPDFAKVSPCLPLLSRLLFS-TDAEVLADTCWALSYLLDGPNEKIQAVIDSGVCRRLVELLDHNQNSVVSAALRAVGNIVTGDDIQTQVILNCHALPNLLHLLSSTKESIRKEACWTISNITAGNRLQIQAVIDANIIPMLIDVLNKAEFKTRKEAAWAIANATSGGTAEQIRYIVSQGAIRPLCDLLTVLNPKIVQVGLNALDNILKIGQQDSKQSGMPNPYAIMVEEAYGLDKMEFLQGHDNEQIYRKSFEII 489          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO31940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI7])

HSP 1 Score: 280.796 bits (717), Expect = 1.470e-89
Identity = 152/374 (40.64%), Postives = 226/374 (60.43%), Query Frame = 3
Query:   63 NRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWS---KLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLL 1175
            +R   YKN DKD  +LR+ RN+ +VE+RKAK+ED +QKRRN+ +D L DE  E   +++        +N I     S + +  L A  + RKLLSK KNPPI+D  K+G +P+LV+ +    N  L FE+AWALTNIASG ++ T+AVV AGA+P F+KL++     V EQ++WAL NI GD    RD ++ +G++      +L+F +    +  LR+V W++ NLCR+K    P   I E+LP +  +++   D+    D  WALSY  D     I  +I + +V  L+  L+ QE ++ T +LRA+GN++ GTDEQ    +  G +     LL+H   ++ KE+ W LSNI AGN+SQ+Q  +D   +IPL+
Sbjct:    8 SRLRYYKNKDKDVTALRQRRNEVTVELRKAKREDCMQKRRNVPLD-LPDEKDEKFQRKD--------LNAIVMEAGSDDPSVQLGAVQAARKLLSKDKNPPIDDLIKSGILPILVQCLQREDNHSLQFEAAWALTNIASGTSEQTQAVVNAGAVPFFLKLLNSPRQHVCEQAVWALGNIVGDGPVLRDFVIGYGVV----KPLLKFVNPGVPITFLRNVTWVLVNLCRNKEPPPPIDTIREVLPAL-ALLIHHQDLDILVDTVWALSYLTDGGSHQIQLVIESGVVQYLVPLLSHQEIKLQTAALRAVGNIVTGTDEQTQVVLNHGALSHFTGLLTHHKEKIKKEAVWFLSNITAGNQSQVQEVIDAG-LIPLI 366          
BLAST of Importin subunit alpha vs. Ensembl Nematostella
Match: EDO29161 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4F4])

HSP 1 Score: 247.669 bits (631), Expect = 2.904e-77
Identity = 128/377 (33.95%), Postives = 214/377 (56.76%), Query Frame = 3
Query:  381 KNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            ++G +P+LV+ +    N  L FE+AWALTNIASG ++ T+AVV AGA+P F+KL++     V EQ++WAL NI GD    RD ++ +G++      +L+F +     +  +   W ISN+        P   + ++LP +  +++   D+    D  WALSY  D     I  +I + +V  L+  L+ QE ++ T +LRA+GN++ GTDEQ    +  G +     LL+H   ++ KE+ W LSNI AGN+SQ+Q  +D  ++  ++  +  G++++QKEAAWA+SNM  S   +    L++ N    +  +L   +  VV ++LD +  +   A    +  +   A E+ GG+D IE LQ H++ +IY  +F+++
Sbjct:    1 RSGILPILVQCLQREDNHSLQFEAAWALTNIASGTSEQTQAVVNAGAVPFFLKLLNSPRQHVCEQAVWALGNIVGDGPVLRDFVIGYGVV----KPLLKFVNPGVPFQTQKEAAWAISNMTVSGRREQPLLLLFQVLPAL-ALLIHHQDLDILVDTVWALSYLTDGGSHQIQLVIESGVVQYLVPLLSHQEIKLQTAALRAVGNIVTGTDEQTQVVLNHGALSHFTGLLTHHKEKIKKEAVWFLSNITAGNQSQVQEVIDAGLIPLIIQTLETGEFQTQKEAAWAISNMTVSGRREQVAVLVHCNAVEHLCKLLDVRDTQVVQIVLDGLNNILKMAGD--KATVIATAIEEAGGLDKIELLQHHQNEEIYKLAFEMI 370          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna2 (importin subunit alpha-1 [Source:NCBI gene;Acc:101160561])

HSP 1 Score: 357.066 bits (915), Expect = 2.754e-117
Identity = 188/489 (38.45%), Postives = 286/489 (58.49%), Query Frame = 3
Query:   51 MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI----LRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            MSE  R   +KN  KD   LRR R + +VE+RKAKK+DQ+ KRRN+        +      +N +  +   I EI   L SG+    L A  + RKLLS++K+PPI+     G IP  V  +       + FE++WALTNIASG +  T AVV+ GAIP F+ L++     +SEQ++WAL NIAGD +  RD ++KHG +  + + +    L  ++    LR+V W +SNLCR+K+ + P S + +++P LIR  ++  +D     D  WA+SY  D  +D I  +    L+P L+  L  +E  ++TP+LRAIGN++ GTDEQ  A +  G +     LL HK P + KE+ W LSNI AG +SQIQ  +D  ++  L+D++   DYK+QKEA WAV+N  +    +  +YL+  NV   ++ +LS  +   V+++LDA+  +F   DKIG+ +      E+ GG+D IE+LQ HE+  +Y  + +++
Sbjct:    1 MSETPRLTQFKNKGKDANELRRRRVEVNVELRKAKKDDQMFKRRNVAAAPEEATSPLQERTQNCQNSRQWTIEEIVSGLNSGSRESQLQATQAARKLLSREKHPPIDQMISAGLIPKFVAFLGLMDFPPIQFEASWALTNIASGTSDQTAAVVEGGAIPAFINLVTSPHLHISEQAVWALGNIAGDGSALRDRVIKHGAVAPLLSLLAVPDLNVFTP-GFLRNVTWTLSNLCRNKNPSPPISAVQQVMPALIR--LLHHDDREVLADACWAVSYLTDGSNDRIEIVAGTGLIPRLVKLLGFEELPVITPALRAIGNIVTGTDEQTQAVLDAGALFMFPKLLRHKKPNIQKEAAWTLSNITAGKDSQIQEVIDAGLVPYLVDLLVRADYKTQKEAVWAVTNFTSGGTVQQVVYLVQANVLEPLLNLLSSKDCKTVLVILDAITNIFLAGDKIGESDKLSLMIEEFGGLDKIEALQAHENEMVYKAALNLI 486          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna3 (karyopherin subunit alpha 3 [Source:NCBI gene;Acc:101166015])

HSP 1 Score: 337.806 bits (865), Expect = 9.358e-110
Identity = 179/485 (36.91%), Postives = 295/485 (60.82%), Query Frame = 3
Query:   57 EINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            E +R   +KN  +D E++RR+RN+ +VE+RK K+++ L K+RN+      +E++E S  ++  + +++ +++I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LVK +  + N  L FE+AWALTNIASG +  T+AVVK+ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W+I NLCR+K    P   + E+LP +  +++   D+    D  WALSY  D  ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C V++   +LLSH   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+ +QKEAAWA+SN+  S       +L+ +NV      +LS  ++ VV ++LD ++ +   A +  +        E+ GG++ IE LQ+HE+ DIY  +F+I+
Sbjct:    8 ENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP----QEESLEDSDVDSDFKGQNVTLDDILQNATSDNAVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALC-MLIYHTDLNILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLLHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEFLVEHNVIPPFCSLLSVKDSQVVQVVLDGLKNILIMAGQ--EASTIAEIIEECGGLEKIEQLQQHENEDIYKLAFEII 481          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna4 (karyopherin subunit alpha 4 [Source:NCBI gene;Acc:101173644])

HSP 1 Score: 327.405 bits (838), Expect = 8.952e-106
Identity = 174/478 (36.40%), Postives = 282/478 (59.00%), Query Frame = 3
Query:   78 YKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSK---LEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +KN  +D E++RR R +  VE+RK K+++ L KRRN+  +DL ++    S  +     ++ ++  I +   S N    L A  + RKLLS  +NPPI+D  K+G +P+LV  +  + N  L FE+AWALTNIASG ++ T+AVV++ A+P+F++L+      V EQ++WAL NI GD  + RD ++  G++      +L F S    +  LR+V W++ NLCRHK    P   I E+LP +  +++   DV+   D  WALSY  D+ ++ I  +I + +VP L+  L+ QE ++ T +LRA+GN++ GTDEQ    + C  +     LL+H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++ ++  GD+ +QKEAAWA+SN+  S       +L+   V      +L+  +  VV ++LD +  +   AD   + E   N  E+ GG++ +E LQ HE+ DIY  +++I+
Sbjct:   15 FKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDLCED----SDLDGDFRSQNTSLEAIVQNATSDNQGVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV----KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALC-VLIHHTDVSILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAKLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAHLIEKQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADD--EAETIANLIEECGGLEKVEQLQNHENEDIYKLAYEII 481          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: KPNA2 (karyopherin subunit alpha 2 [Source:NCBI gene;Acc:101159727])

HSP 1 Score: 319.701 bits (818), Expect = 8.254e-103
Identity = 173/488 (35.45%), Postives = 283/488 (57.99%), Query Frame = 3
Query:   66 RRNLYKNGDK-DFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDD----LSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHG----IIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            R +L+KN  K   ESLRR R +  VE+RKAKK++Q+ KRR I  DD    L D+N               ++ EI   + S N+   + A  + R  LS++K+PP++     G IP LV  +  ++N  + FE+AWALTNIASG +  T++V+  GA+P FV L+S     +S+Q+IWAL NIAGD A  RD+++ HG    ++ +++   L  +     LR+V W +SNLCRHK+   P + + ++LP++  ++   +D     D   ALS+  D  ++ I  ++  + VP L+  L+ ++  IVTP+LR IGN++ GTDEQ    +  G +     LL + NP + KE+ W +SNI AG  SQIQ  ++  ++  L+D+++ GDYK+Q+EA WAV+N  +        YL++ N    ++ +L   ++ V++++LDA+  +   +   G++E      E +GG+D +E+LQ H++  +Y  S +I+
Sbjct:   11 RIHLFKNKGKCALESLRR-RAEVKVELRKAKKDEQIFKRRAIQQDDPASLLHDKNYRGQC---------WSVEEIVGAVNSQNLEHQVQAVQAARAFLSREKSPPVDGIIAAGLIPTLVGFLALSENPPIQFEAAWALTNIASGTSHQTKSVIAGGAVPAFVSLISSPHQHISQQAIWALGNIAGDGADSRDLVIHHGGLQPLLALLETSDLSVFGS-SYLRNVTWALSNLCRHKNPAPPLASVRQMLPVLAHLLHH-DDREVLADTCRALSHLTDGANERIEMVVDTDCVPRLVQLLSCEDVSIVTPALRTIGNIVTGTDEQTQCVLNAGALAVFPVLLGYPNPNIQKEAAWAVSNITAGKSSQIQEVINAGLVPMLVDILQQGDYKTQREAVWAVTNYTSGGTVDQVAYLVHCNALEPLIQLLHIKDSRVILVILDAIDNILQMSKDTGEVEKVRLLIEGLGGLDTLEALQSHDNEAVYKSSLNII 486          
BLAST of Importin subunit alpha vs. Ensembl Medaka
Match: kpna2 (importin subunit alpha-1 [Source:NCBI gene;Acc:101160561])

HSP 1 Score: 318.546 bits (815), Expect = 9.711e-103
Identity = 167/448 (37.28%), Postives = 259/448 (57.81%), Query Frame = 3
Query:  174 KRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCI----LRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLP-LIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            KRRN+        +      +N +  +   I EI   L SG+    L A  + RKLLS++K+PPI+     G IP  V  +       + FE++WALTNIASG +  T AVV+ GAIP F+ L++     +SEQ++WAL NIAGD +  RD ++KHG +  + + +    L  ++    LR+V W +SNLCR+K+ + P S + +++P LIR  ++  +D     D  WA+SY  D  +D I  +    L+P L+  L  +E  ++TP+LRAIGN++ GTDEQ  A +  G +     LL HK P + KE+ W LSNI AG +SQIQ  +D  ++  L+D++   DYK+QKEA WAV+N  +    +  +YL+  NV   ++ +LS  +   V+++LDA+  +F   DKIG+ +      E+ GG+D IE+LQ HE+  +Y  + +++
Sbjct:    3 KRRNVAAAPEEATSPLQERTQNCQNSRQWTIEEIVSGLNSGSRESQLQATQAARKLLSREKHPPIDQMISAGLIPKFVAFLGLMDFPPIQFEASWALTNIASGTSDQTAAVVEGGAIPAFINLVTSPHLHISEQAVWALGNIAGDGSALRDRVIKHGAVAPLLSLLAVPDLNVFTP-GFLRNVTWTLSNLCRNKNPSPPISAVQQVMPALIR--LLHHDDREVLADACWAVSYLTDGSNDRIEIVAGTGLIPRLVKLLGFEELPVITPALRAIGNIVTGTDEQTQAVLDAGALFMFPKLLRHKKPNIQKEAAWTLSNITAGKDSQIQEVIDAGLVPYLVDLLVRADYKTQKEAVWAVTNFTSGGTVQQVVYLVQANVLEPLLNLLSSKDCKTVLVILDAITNIFLAGDKIGESDKLSLMIEEFGGLDKIEALQAHENEMVYKAALNLI 447          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000063514.1 (SMESG000063514.1)

HSP 1 Score: 978.393 bits (2528), Expect = 0.000e+0
Identity = 507/508 (99.80%), Postives = 507/508 (99.80%), Query Frame = 3
Query:   51 MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIVXXXXXXXXXXXXXXXXXXXXXYHF 1574
            MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKS NITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIVKEFLNGDEEDEENDEPNKAEKYHF
Sbjct:    1 MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSDNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIVKEFLNGDEEDEENDEPNKAEKYHF 508          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000058125.1 (SMESG000058125.1)

HSP 1 Score: 325.865 bits (834), Expect = 2.406e-105
Identity = 177/483 (36.65%), Postives = 285/483 (59.01%), Query Frame = 3
Query:   63 NRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWS---KLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +RRN++KN  KD + +RR R + +VE+RK K+E+ LQKRRN+        ++E    E  + ++  N++EI     + N T  L+A  + RKLLS  KNPPI++  ++G +P+LV+ + ++ +  + FE+AWALTNIASG ++ T AVV+AGA+P+F+KL+  +   V EQ++WAL NI GD    RD  +  G++      +L+F +    +  LR+V W+I NLCR+K        I ELLP +R ++  I D     D  WALSY  D  +D I  +I  ++V  L+  L+  + ++ T +LRA+GN++ GTDEQ    +    +     LL H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+++QKEAAW +SN+  S   +   +++   V      +LS  +  VV ++LD +  +   A+   Q +L     E+ GG+D+IE LQ HE+ +IY  ++DI+
Sbjct:    3 DRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL-------PSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVA----PLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNI-DTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDII 471          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000058125.1 (SMESG000058125.1)

HSP 1 Score: 318.546 bits (815), Expect = 1.237e-102
Identity = 174/479 (36.33%), Postives = 281/479 (58.66%), Query Frame = 3
Query:   75 LYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWS---KLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            ++KN  KD + +RR R + +VE+RK K+E+ LQKRRN+        ++E    E  + ++  N++EI     + N T  L+A  + RKLLS  KNPPI++  ++G +P+LV+ + ++ +  + FE+AWALTNIASG ++ T AVV+AGA+P+F+KL+  +   V EQ++WAL NI GD    RD  +  G++      +L+F +    +  LR+V W+I NLCR+K        I ELLP +R ++  I D     D  WALSY  D  +D I  +I  ++V  L+  L+  + ++ T +LRA+GN++ GTDEQ    +    +     LL H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+++QKEAAW +SN+  S   +   +++   V      +LS  +  VV ++LD +  +   A+   Q +L     E+ GG+D+IE LQ HE+ +IY  ++DI+
Sbjct:    1 MHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL-------PSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVA----PLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNI-DTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDII 465          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000055942.1 (SMESG000055942.1)

HSP 1 Score: 315.849 bits (808), Expect = 4.094e-102
Identity = 174/475 (36.63%), Postives = 279/475 (58.74%), Query Frame = 3
Query:   63 NRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWS---KLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDI 1478
            +RRN++KN  KD + +RR R + +VE+RK K+E+ LQKRRN+        ++E    E  + ++  N++EI     + N T  L+A  + RKLLS  KNPPI++  ++G +P+LV+ + ++ +  + FE+AWALTNIASG ++ T AVV+AGA+P+F+KL+  +   V EQ++WAL NI GD    RD  +  G++      +L+F+       +LR+V W+I NLCR+K        I ELLP +R ++  I D     D  WALSY  D  +D I  +I  ++V  L+  L+  + ++ T +LRA+GN++ GTDEQ    +    +     LL H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+++QKEAAW +SN+  S   +   +++   V      +LS  +  VV ++LD +  +   A+   Q +L     E+ GG+D+IE LQ HE+ +I
Sbjct:    3 DRRNMHKNASKDTDEMRRRRVEGNVELRKNKREETLQKRRNL-------PSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVA----PLLKFFKCRCTNNLLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNI-DTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEI 463          
BLAST of Importin subunit alpha vs. Planmine SMEST
Match: SMESG000058125.1 (SMESG000058125.1)

HSP 1 Score: 309.301 bits (791), Expect = 3.617e-99
Identity = 170/468 (36.32%), Postives = 274/468 (58.55%), Query Frame = 3
Query:  108 LRRNRNDHSVEIRKAKKEDQLQKRRNIVIDDLSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSKQKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTEAVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGIIDVVKNCILRFWS---KLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREIMVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECEIVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWVLSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSANDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLELCINAFEDVGGIDIIESLQEHESVDIYTKSFDIV 1502
            +RR R + +VE+RK K+E+ LQKRRN+        ++E    E  + ++  N++EI     + N T  L+A  + RKLLS  KNPPI++  ++G +P+LV+ + ++ +  + FE+AWALTNIASG ++ T AVV+AGA+P+F+KL+  +   V EQ++WAL NI GD    RD  +  G++      +L+F +    +  LR+V W+I NLCR+K        I ELLP +R ++  I D     D  WALSY  D  +D I  +I  ++V  L+  L+  + ++ T +LRA+GN++ GTDEQ    +    +     LL H   ++ KE+ W LSNI AGN+ Q+QA +D  ++  ++  +  GD+++QKEAAW +SN+  S   +   +++   V      +LS  +  VV ++LD +  +   A+   Q +L     E+ GG+D+IE LQ HE+ +IY  ++DI+
Sbjct:    1 MRRRRVEGNVELRKNKREETLQKRRNL-------PSLEADENEIEEPLQMGNLSEIVANSTNPNPTVRLEAIQAARKLLSSDKNPPIDNLIQSGIMPILVECLDNDAHPNIQFEAAWALTNIASGTSEQTNAVVQAGAVPLFLKLLGSTHSNVCEQAVWALGNIIGDGPTLRDYAISLGVVA----PLLKFLNADVPITFLRNVTWVIVNLCRNKDPPPSPVTISELLPALRFLIQNI-DTNILVDTVWALSYLTDGGNDQIQMVIEADIVRFLVPLLSHNDVKVQTAALRAVGNIVTGTDEQTQYVLNFDALSHFPQLLQHSKEKINKEAVWFLSNITAGNQEQVQAVIDYSLIPLIIYHLDKGDFQTQKEAAWVISNLTISGTPQQVAFVVQQGVIPPFCKMLSVRDAQVVQVVLDGILNILKVAND--QSDLVCTMIEECGGLDLIEQLQHHENGEIYKLAYDII 454          
The following BLAST results are available for this feature:
BLAST of Importin subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KPNA21.417e-10836.65karyopherin subunit alpha 2 [Source:HGNC Symbol;Ac... [more]
KPNA21.417e-10836.65karyopherin subunit alpha 2 [Source:HGNC Symbol;Ac... [more]
KPNA31.258e-10736.91karyopherin subunit alpha 3 [Source:HGNC Symbol;Ac... [more]
KPNA41.510e-10736.82karyopherin subunit alpha 4 [Source:HGNC Symbol;Ac... [more]
KPNA72.792e-9535.14karyopherin subunit alpha 7 [Source:HGNC Symbol;Ac... [more]
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BLAST of Importin subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ima-37.759e-9534.98Importin subunit alpha-3 [Source:UniProtKB/Swiss-... [more]
ima-21.981e-8134.40Importin subunit alpha-2 [Source:UniProtKB/Swiss-... [more]
F53B2.53.751e-1723.06pep chromosome:WBcel235:IV:12528529:12531166:-1 ge... [more]
ima-16.781e-1325.96Importin subunit alpha-1 [Source:UniProtKB/Swiss-... [more]
ima-16.781e-1325.96Importin subunit alpha-1 [Source:UniProtKB/Swiss-... [more]
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BLAST of Importin subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kap-alpha34.898e-10536.65gene:FBgn0027338 transcript:FBtr0301189[more]
Kap-alpha34.898e-10536.65gene:FBgn0027338 transcript:FBtr0082106[more]
Kap-alpha34.898e-10536.65gene:FBgn0027338 transcript:FBtr0082108[more]
Kap-alpha34.898e-10536.65gene:FBgn0027338 transcript:FBtr0082107[more]
Pen1.306e-9935.06gene:FBgn0267727 transcript:FBtr0079937[more]
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BLAST of Importin subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna25.541e-11338.48karyopherin alpha 2 (RAG cohort 1, importin alpha ... [more]
kpna38.841e-10836.70karyopherin alpha 3 (importin alpha 4) [Source:ZFI... [more]
kpna44.415e-10736.82karyopherin alpha 4 (importin alpha 3) [Source:ZFI... [more]
kpna71.126e-9935.98karyopherin alpha 7 (importin alpha 8) [Source:ZFI... [more]
kpna52.145e-8532.72karyopherin alpha 5 (importin alpha 6) [Source:NCB... [more]
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BLAST of Importin subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna72.703e-11436.85karyopherin alpha 7 (importin alpha 8) [Source:NCB... [more]
kpna73.331e-11136.73karyopherin alpha 7 (importin alpha 8) [Source:NCB... [more]
acp43.348e-10937.24acid phosphatase 4 [Source:Xenbase;Acc:XB-GENE-960... [more]
kpna31.601e-10636.29karyopherin alpha 3 (importin alpha 4) [Source:NCB... [more]
acp44.116e-10637.05acid phosphatase 4 [Source:Xenbase;Acc:XB-GENE-960... [more]
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BLAST of Importin subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gm101842.077e-11037.32predicted pseudogene 10184 [Source:MGI Symbol;Acc:... [more]
Kpna22.077e-11037.32karyopherin (importin) alpha 2 [Source:MGI Symbol;... [more]
Kpna41.063e-10837.03karyopherin (importin) alpha 4 [Source:MGI Symbol;... [more]
Kpna42.320e-10737.03karyopherin (importin) alpha 4 [Source:MGI Symbol;... [more]
Kpna33.722e-10736.70karyopherin (importin) alpha 3 [Source:MGI Symbol;... [more]
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BLAST of Importin subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P52171|IMA1_XENLA7.314e-11637.68Importin subunit alpha-1 OS=Xenopus laevis OX=8355... [more]
sp|P52170|IMA5_XENLA1.579e-11437.29Importin subunit alpha-5 OS=Xenopus laevis OX=8355... [more]
sp|P52293|IMA1_MOUSE1.453e-10937.32Importin subunit alpha-1 OS=Mus musculus OX=10090 ... [more]
sp|P52292|IMA1_HUMAN6.806e-10836.65Importin subunit alpha-1 OS=Homo sapiens OX=9606 G... [more]
sp|O35343|IMA3_MOUSE7.433e-10837.03Importin subunit alpha-3 OS=Mus musculus OX=10090 ... [more]
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BLAST of Importin subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K4F0D46.656e-12640.54Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A0X3PDU13.440e-12539.88Importin subunit alpha OS=Schistocephalus solidus ... [more]
A0A0R3X6M73.214e-12239.92Importin subunit alpha OS=Hydatigena taeniaeformis... [more]
A0A0R3UJ804.776e-12240.04Importin subunit alpha OS=Mesocestoides corti OX=5... [more]
A0A267FVN37.351e-12239.81IBB domain-containing protein (Fragment) OS=Macros... [more]
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BLAST of Importin subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna23.021e-11338.35importin subunit alpha-1-like [Source:NCBI gene;Ac... [more]
KPNA22.314e-11038.73karyopherin subunit alpha 2 [Source:NCBI gene;Acc:... [more]
kpna31.140e-10836.83karyopherin subunit alpha 3 [Source:NCBI gene;Acc:... [more]
kpna41.976e-10636.82karyopherin subunit alpha 4 [Source:NCBI gene;Acc:... [more]
kpna37.907e-10536.81karyopherin subunit alpha 3 [Source:NCBI gene;Acc:... [more]
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BLAST of Importin subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna72.728e-11036.25karyopherin alpha 7 (importin alpha 8) [Source:ZFI... [more]
kpna42.695e-10535.99karyopherin alpha 4 (importin alpha 3) [Source:ZFI... [more]
ENSPMAT00000005568.13.390e-6232.66pep scaffold:Pmarinus_7.0:GL477092:38612:43101:1 g... [more]
kpna63.086e-2528.48karyopherin alpha 6 (importin alpha 7) [Source:ZFI... [more]
ENSPMAT00000008519.15.117e-2539.20pep scaffold:Pmarinus_7.0:GL480915:29739:34392:1 g... [more]
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BLAST of Importin subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SRP13.283e-9034.00Karyopherin alpha homolog; forms a dimer with kary... [more]
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BLAST of Importin subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO306482.025e-10637.01Importin subunit alpha [Source:UniProtKB/TrEMBL;A... [more]
EDO383373.239e-9033.47Importin subunit alpha [Source:UniProtKB/TrEMBL;A... [more]
EDO319401.470e-8940.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO291612.904e-7733.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Importin subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kpna22.754e-11738.45importin subunit alpha-1 [Source:NCBI gene;Acc:101... [more]
kpna39.358e-11036.91karyopherin subunit alpha 3 [Source:NCBI gene;Acc:... [more]
kpna48.952e-10636.40karyopherin subunit alpha 4 [Source:NCBI gene;Acc:... [more]
KPNA28.254e-10335.45karyopherin subunit alpha 2 [Source:NCBI gene;Acc:... [more]
kpna29.711e-10337.28importin subunit alpha-1 [Source:NCBI gene;Acc:101... [more]
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BLAST of Importin subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000063514.10.000e+099.80SMESG000063514.1[more]
SMESG000058125.12.406e-10536.65SMESG000058125.1[more]
SMESG000058125.11.237e-10236.33SMESG000058125.1[more]
SMESG000055942.14.094e-10236.63SMESG000055942.1[more]
SMESG000058125.13.617e-9936.32SMESG000058125.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30012458 ID=SMED30012458|Name=Importin subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=1623bp
TAACACATTTGTTTTATTTTGTCATTATTTTAAATTTATTTTCACGTTAG
ATGTCTGAAATTAATCGCAGAAACCTTTATAAGAACGGCGATAAAGATTT
TGAAAGTTTGCGTCGTAATAGAAATGATCACTCTGTTGAAATTAGAAAAG
CCAAAAAAGAAGATCAATTACAGAAAAGAAGAAATATTGTCATTGATGAT
TTGTCGGATGAAAACATAGAAGTATCTTCTAAAGAAAATGTTAAGGAAAT
AAAAGATATAAATATAAATGAAATCCCAAAGTTGTTGAAATCTGGCAATA
TTACACAAATGTTAGATGCAGCTACATCATGCAGAAAACTATTATCAAAA
CAAAAAAATCCACCTATTGAAGATTTTTATAAAAATGGAACAATTCCATT
ATTGGTAAAAATCATGACCGATAATAAAAATGAAATTTTGACTTTTGAAA
GTGCTTGGGCATTAACAAATATCGCATCAGGCGACAATAAACATACTGAA
GCGGTTGTCAAGGCTGGAGCCATTCCAGTATTCGTTAAATTAATGTCTTG
TTCAACTGATCAAGTATCAGAGCAGTCAATATGGGCTTTGAGTAACATTG
CCGGTGACAGTGCCAAATATCGAGACATGATTGTCAAGCATGGGATCATC
GATGTTGTGAAAAACTGTATATTGCGATTCTGGAGTAAGTTGGAAGTATT
GCGTCATGTATGCTGGTTAATCTCGAATCTTTGTCGTCATAAGAGCACGA
ATTTTCCTTCTTCTGGGATAATCGAATTGTTGCCTCTCATCCGAGAAATA
ATGGTTGAAATCAATGATGTTGCCTGCACGTGTGACCTTAATTGGGCGTT
GTCCTATGCTATCGATTCACGTGATGATATAATCAATGCATTGATCGCCA
ATGAATTGGTTCCAGTTCTTATTGCCAATCTGAACAGACAGGAATGTGAA
ATAGTTACTCCATCGTTAAGGGCAATAGGAAATGTTATTGCCGGAACCGA
TGAACAAGCCGATGCTGCTATCAAATGTGGAGTTATCATTTCCGTTGGAC
ACCTGTTATCTCACAAAAACCCCAGATTGGTAAAGGAGAGCTGTTGGGTG
CTTAGTAACATCATTGCCGGAAACGAATCGCAGATCCAAGCCTGTGTAGA
TTGTGACGTGATGATCCCGTTGTTGGATGTAATGAGAAATGGAGATTACA
AGTCTCAGAAAGAGGCCGCGTGGGCAGTAAGTAACATGGCAAACAGCGCT
AATGACAAACACAAATTGTATTTGCTAAATAACAATGTATTCCATGCAAT
TGTTCCTATACTATCATGTAATGAAAATGATGTTGTTATCTTGCTTTTGG
ATGCTGTCCGTGAACTGTTCACCTGTGCTGACAAGATCGGTCAACTTGAA
CTATGCATTAATGCTTTCGAGGATGTTGGGGGCATTGATATCATTGAGAG
TCTTCAGGAACATGAATCAGTCGATATCTATACAAAGAGTTTTGATATCG
TCAAAGAATTTTTGAATGGAGATGAAGAGGATGAAGAAAATGACGAGCCA
AATAAAGCGGAGAAATATCACTTTTAGATTTATGTTAGATGTTTAGAAGT
TTAATAAATGTTATATTATTGAA
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protein sequence of SMED30012458-orf-1

>SMED30012458-orf-1 ID=SMED30012458-orf-1|Name=SMED30012458-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=509bp
MSEINRRNLYKNGDKDFESLRRNRNDHSVEIRKAKKEDQLQKRRNIVIDD
LSDENIEVSSKENVKEIKDININEIPKLLKSGNITQMLDAATSCRKLLSK
QKNPPIEDFYKNGTIPLLVKIMTDNKNEILTFESAWALTNIASGDNKHTE
AVVKAGAIPVFVKLMSCSTDQVSEQSIWALSNIAGDSAKYRDMIVKHGII
DVVKNCILRFWSKLEVLRHVCWLISNLCRHKSTNFPSSGIIELLPLIREI
MVEINDVACTCDLNWALSYAIDSRDDIINALIANELVPVLIANLNRQECE
IVTPSLRAIGNVIAGTDEQADAAIKCGVIISVGHLLSHKNPRLVKESCWV
LSNIIAGNESQIQACVDCDVMIPLLDVMRNGDYKSQKEAAWAVSNMANSA
NDKHKLYLLNNNVFHAIVPILSCNENDVVILLLDAVRELFTCADKIGQLE
LCINAFEDVGGIDIIESLQEHESVDIYTKSFDIVKEFLNGDEEDEENDEP
NKAEKYHF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0042025host cell nucleus
GO:0005737cytoplasm
GO:0005634nucleus
Vocabulary: molecular function
TermDefinition
GO:0061608nuclear import signal receptor activity
GO:0005515protein binding
GO:0008565protein transporter activity
GO:0005488binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000420parapharyngeal region
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR000225Armadillo
IPR002652Importin-a_IBB
IPR024931Importing_su_alpha
IPR032413Arm_3
IPR011989ARM-like
IPR016024ARM-type_fold
Vocabulary: biological process
TermDefinition
GO:0006606protein import into nucleus
GO:0006810transport
GO:0015031protein transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000225ArmadilloSMARTSM00185arm_5coord: 101..143
e-value: 0.42
score: 19.7
coord: 230..270
e-value: 5.3E-5
score: 32.6
coord: 272..312
e-value: 2.5E-5
score: 33.7
coord: 188..228
e-value: 31.0
score: 9.4
coord: 59..99
e-value: 7.1E-8
score: 42.2
coord: 315..355
e-value: 110.0
score: 5.1
coord: 16..57
e-value: 1.8E-4
score: 30.9
IPR000225ArmadilloPFAMPF00514Armcoord: 231..268
e-value: 2.5E-7
score: 30.5
coord: 273..311
e-value: 2.1E-7
score: 30.7
coord: 59..98
e-value: 1.4E-9
score: 37.7
coord: 18..57
e-value: 5.7E-5
score: 23.0
IPR000225ArmadilloPROSITEPS50176ARM_REPEATcoord: 27..70
score: 9.362
IPR000225ArmadilloPROSITEPS50176ARM_REPEATcoord: 70..112
score: 9.677
IPR011989Armadillo-like helicalGENE3DG3DSA:1.25.10.10coord: 1..403
e-value: 3.2E-122
score: 410.0
IPR032413Atypical Arm repeatPFAMPF16186Arm_3coord: 368..414
e-value: 4.1E-13
score: 48.7
NoneNo IPR availablePANTHERPTHR23316IMPORTIN ALPHAcoord: 2..411
NoneNo IPR availablePANTHERPTHR23316:SF11IMPORTIN SUBUNIT ALPHA-8coord: 2..411
IPR016024Armadillo-type foldSUPERFAMILYSSF48371ARM repeatcoord: 3..406