EGR-1

Overview


Name	EGR-1 (AFD29624.1)
Smed ID	SMED30012332
Length (bp)	1460

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of EGR-1 (SMED30012332) t-SNE clustered cells

Violin plots show distribution of expression levels for EGR-1 (SMED30012332) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EGR-1 (SMED30012332) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EGR-1 (SMED30012332) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012332

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 27

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
zeta neoblast	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:29906446 Zeng et al., 2018
pigment cell	SMED30012332	SMESG000034285.1	SmedASXL_008042	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
pigment cell	SMED30012332	SMESG000034285.1	SmedASXL_065460	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
Category 2 cell	SMED30012332	SMESG000034285.1	SmedASXL_008042	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30012332	SMESG000034285.1	SmedASXL_008042	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30012332	SMESG000034285.1	SmedASXL_008042	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
parenchyma	SMED30012332	SMESG000034285.1	SmedASXL_008042	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30012332	SMESG000034285.1	SmedASXL_065460	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30012332	SMESG000034285.1	SmedASXL_065460	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Category 2 cell	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:29100657 Cheng et al., 2018
Category 3 cell	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:29100657 Cheng et al., 2018
neoblast	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:29100657 Cheng et al., 2018
X1 cell	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:29100657 Cheng et al., 2018
epidermis	SMED30012332	SMESG000034285.1	dd_Smed_v4_3935_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30012332	SMESG000034285.1	dd_Smed_v4_3935_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30012332	SMESG000034285.1	dd_Smed_v4_3935_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30012332	SMESG000034285.1	Contig48378	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30012332	SMESG000034285.1	Contig48378	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
zeta neoblast	SMED30012332	SMESG000034285.1	JQ425156	smed_ncbi_20200123	PMID:25017721 van Wolfswinkel et al., 2014
zeta neoblast	SMED30012332	SMESG000034285.1	JQ425156	smed_ncbi_20200123	PMID:25017721 van Wolfswinkel et al., 2014
Category 2 cell	SMED30012332	SMESG000034285.1	dd_Smed_v6_3935_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30012332	SMESG000034285.1	SMED_00244_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30012332	SMESG000034285.1	SMED_00244_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30012332	SMESG000034285.1	SmWIOct06_019211	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30012332	SMESG000034285.1	SmWIOct06_008915	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:22385657 Wagner et al., 2012
neoblast	SMED30012332	SMESG000034285.1	SMED30012332	smed_20140614	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of EGR-1 vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 105.145 bits (261), Expect = 4.318e-24
Identity = 49/85 (57.65%), Postives = 59/85 (69.41%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
             C  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP++CE C + FARSDER RH +IH K   +K +K
Sbjct:  281 GCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEK 365

HSP 2 Score: 52.373 bits (124), Expect = 1.126e-6
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  303 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359

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BLAST of EGR-1 vs. Ensembl Human
Match: EGR1 (early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238])

HSP 1 Score: 106.686 bits (265), Expect = 4.699e-24
Identity = 53/102 (51.96%), Postives = 67/102 (65.69%), Query Frame = 2

Query:  611 RISREEKSKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH
Sbjct:  317 KPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 418

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BLAST of EGR-1 vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 103.99 bits (258), Expect = 8.407e-24
Identity = 49/85 (57.65%), Postives = 59/85 (69.41%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
             C  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP++CE C + FARSDER RH +IH K   +K +K
Sbjct:  243 GCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEK 327

HSP 2 Score: 51.6026 bits (122), Expect = 1.637e-6
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  265 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 321

[Close]

BLAST of EGR-1 vs. Ensembl Human
Match: EGR2 (early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239])

HSP 1 Score: 103.605 bits (257), Expect = 4.319e-23
Identity = 57/120 (47.50%), Postives = 71/120 (59.17%), Query Frame = 2

Query:  590 PLHDPISRISREEKSKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKP 943
            P H P+  I R  K  +  S     ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+ C + FARSDER RHT+IH +   RK   P
Sbjct:  312 PHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAP 431

[Close]

Query:  590 PLHDPISRISREEKSKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKP 943
            P H P+  I R  K  +  S     ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+ C + FARSDER RHT+IH +   RK   P
Sbjct:  312 PHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAP 431

[Close]

BLAST of EGR-1 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 106.301 bits (264), Expect = 1.267e-25
Identity = 51/86 (59.30%), Postives = 60/86 (69.77%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSK 916
            D+ + C    C  +F+R DEL RH +IHTG K   C  C + F RSDH  TH+RTHTGEKPYSC+IC K FAR DERTRHT+IH K
Sbjct:  175 DRPYKCPRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKK 260

[Close]

BLAST of EGR-1 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 106.301 bits (264), Expect = 1.565e-25
Identity = 53/93 (56.99%), Postives = 62/93 (66.67%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            D+ + C    C  +F+R DEL RH +IHTG K   C  C + F RSDH  TH+RTHTGEKPYSC+IC K FAR DERTRHT+IH K    K K
Sbjct:  175 DRPYKCPRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGPGKHK 267

HSP 2 Score: 49.2914 bits (116), Expect = 2.781e-6
Identity = 25/65 (38.46%), Postives = 30/65 (46.15%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICC 862
            K F C  C  RF+R D L  H + HTG K   C  C K F R D R  H + H    P   ++ C
Sbjct:  206 KPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGPGKHKMKC 270

[Close]

BLAST of EGR-1 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 100.138 bits (248), Expect = 3.587e-25
Identity = 51/86 (59.30%), Postives = 60/86 (69.77%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSK 916
            D+ + C    C  +F+R DEL RH +IHTG K   C  C + F RSDH  TH+RTHTGEKPYSC+IC K FAR DERTRHT+IH K
Sbjct:   10 DRPYKCPRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKK 95

[Close]

BLAST of EGR-1 vs. Ensembl Celegans
Match: egrh-1 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:Q18250])

HSP 1 Score: 107.071 bits (266), Expect = 1.012e-24
Identity = 51/92 (55.43%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  644 KSNQLP-PDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            KS+++P  D+ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  TH+RTHTGEKP+SC+IC + FARSDER RHT++H
Sbjct:  363 KSSKMPLQDRPYKCPRDGCDRRFSRSDELTRHIRIHTGQKPFQCRICMRAFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDERKRHTKVH 454

HSP 2 Score: 61.6178 bits (148), Expect = 5.334e-10
Identity = 27/54 (50.00%), Postives = 34/54 (62.96%), Query Frame = 2

Query:  764 CP--YCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            CP   CD+ F RSD    HIR HTG+KP+ C IC + F+RSD  T H R H+ +
Sbjct:  376 CPRDGCDRRFSRSDELTRHIRIHTGQKPFQCRICMRAFSRSDHLTTHVRTHTGE 429

[Close]

BLAST of EGR-1 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 99.3673 bits (246), Expect = 1.087e-24
Identity = 53/93 (56.99%), Postives = 62/93 (66.67%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            D+ + C    C  +F+R DEL RH +IHTG K   C  C + F RSDH  TH+RTHTGEKPYSC+IC K FAR DERTRHT+IH K    K K
Sbjct:   10 DRPYKCPRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGPGKHK 102

[Close]

BLAST of EGR-1 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0330050)

HSP 1 Score: 111.694 bits (278), Expect = 1.458e-25
Identity = 50/93 (53.76%), Postives = 65/93 (69.89%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            ++ + C   NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SC+IC + FARSDE+ RH ++H K  ++K K
Sbjct: 1033 ERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEK 1125

[Close]

BLAST of EGR-1 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0083542)

HSP 1 Score: 111.309 bits (277), Expect = 1.910e-25
Identity = 50/93 (53.76%), Postives = 65/93 (69.89%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            ++ + C   NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SC+IC + FARSDE+ RH ++H K  ++K K
Sbjct: 1033 ERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEK 1125

[Close]

BLAST of EGR-1 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0301615)

HSP 1 Score: 110.153 bits (274), Expect = 3.349e-25
Identity = 50/93 (53.76%), Postives = 65/93 (69.89%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            ++ + C   NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SC+IC + FARSDE+ RH ++H K  ++K K
Sbjct:  564 ERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEK 656

[Close]

BLAST of EGR-1 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0344633)

HSP 1 Score: 109.768 bits (273), Expect = 5.083e-25
Identity = 50/93 (53.76%), Postives = 65/93 (69.89%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            ++ + C   NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SC+IC + FARSDE+ RH ++H K  ++K K
Sbjct:  753 ERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEK 845

[Close]

BLAST of EGR-1 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0083543)

HSP 1 Score: 109.768 bits (273), Expect = 5.083e-25
Identity = 50/93 (53.76%), Postives = 65/93 (69.89%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            ++ + C   NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SC+IC + FARSDE+ RH ++H K  ++K K
Sbjct:  753 ERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEK 845

[Close]

BLAST of EGR-1 vs. Ensembl Zebrafish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:30498])

HSP 1 Score: 108.997 bits (271), Expect = 4.797e-25
Identity = 56/110 (50.91%), Postives = 70/110 (63.64%), Query Frame = 2

Query:  617 SREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            SR  K  +  S   P ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++CEIC + FARSDER RHT+IH +   +K +K
Sbjct:  292 SRMRKYPNRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEK 401

[Close]

Query:  617 SREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            SR  K  +  S   P ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++CEIC + FARSDER RHT+IH +   +K +K
Sbjct:  292 SRMRKYPNRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEK 401

[Close]

BLAST of EGR-1 vs. Ensembl Zebrafish
Match: egr3 (early growth response 3 [Source:ZFIN;Acc:ZDB-GENE-040718-394])

HSP 1 Score: 106.301 bits (264), Expect = 1.692e-24
Identity = 52/86 (60.47%), Postives = 61/86 (70.93%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKP 943
            NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SCE C + FARSDER RH ++H K   +K KKP
Sbjct:  303 NCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLK---QKDKKP 385

HSP 2 Score: 51.2174 bits (121), Expect = 1.864e-6
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  325 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 381

[Close]

BLAST of EGR-1 vs. Ensembl Zebrafish
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 104.76 bits (260), Expect = 2.493e-24
Identity = 51/94 (54.26%), Postives = 65/94 (69.15%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            +K F+C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  TH+RTHTGEKP+SC++C + FARSDER RH R+H K   R ++K
Sbjct:  247 EKPFSCPVESCERRFSRSDELNRHVRIHTGHKPFQCRVCLRCFSRSDHLTTHMRTHTGEKPFSCDVCARRFARSDERKRHMRVHLKQRERMQQK 340

[Close]

BLAST of EGR-1 vs. Ensembl Zebrafish
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 101.293 bits (251), Expect = 6.414e-24
Identity = 60/132 (45.45%), Postives = 77/132 (58.33%), Query Frame = 2

Query:  542 PLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            PLD +   N  N+ L P+  P    +R  K+          ++ + C    C  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SC+ C + FARSDER RHT+IH +   RK
Sbjct:  114 PLDGT---NPQNVPLRPILRPRKYPNRPCKTPVH-------ERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRK 235

[Close]

BLAST of EGR-1 vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 108.227 bits (269), Expect = 1.160e-24
Identity = 54/104 (51.92%), Postives = 68/104 (65.38%), Query Frame = 2

Query:  605 ISRISREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            I + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH
Sbjct:  284 IIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 387

[Close]

BLAST of EGR-1 vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 107.842 bits (268), Expect = 1.246e-24
Identity = 54/104 (51.92%), Postives = 68/104 (65.38%), Query Frame = 2

Query:  605 ISRISREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            I + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH
Sbjct:  257 IIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 360

[Close]

BLAST of EGR-1 vs. Ensembl Xenopus
Match: usp31 (ubiquitin specific peptidase 31 [Source:Xenbase;Acc:XB-GENE-920956])

HSP 1 Score: 105.145 bits (261), Expect = 1.711e-23
Identity = 50/96 (52.08%), Postives = 63/96 (65.62%), Query Frame = 2

Query:  659 PPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            P +K+F C   +C   F R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP+SC++C + FARSDE+ RH ++H K   R  +K
Sbjct:  435 PHEKAFACPVESCIRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDLCGRRFARSDEKKRHGKVHMKQKARTEEK 530

[Close]

BLAST of EGR-1 vs. Ensembl Xenopus
Match: serpinb4 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:Xenbase;Acc:XB-GENE-5787878])

HSP 1 Score: 100.908 bits (250), Expect = 9.518e-23
Identity = 45/75 (60.00%), Postives = 54/75 (72.00%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
             C  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP++C+ C + FARSDER RH +IH
Sbjct:  278 GCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIH 352

HSP 2 Score: 50.8322 bits (120), Expect = 3.123e-6
Identity = 22/53 (41.51%), Postives = 28/53 (52.83%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTH 826
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H
Sbjct:  300 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIH 352

[Close]

BLAST of EGR-1 vs. Ensembl Xenopus
Match: tbl1x (transducin beta like 1 X-linked [Source:Xenbase;Acc:XB-GENE-982285])

HSP 1 Score: 100.523 bits (249), Expect = 1.987e-22
Identity = 48/82 (58.54%), Postives = 57/82 (69.51%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
             C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+ C + FARSDER RHT+IH +   RK
Sbjct:  267 GCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERK 348

[Close]

BLAST of EGR-1 vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 105.145 bits (261), Expect = 3.080e-24
Identity = 49/85 (57.65%), Postives = 59/85 (69.41%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
             C  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP++CE C + FARSDER RH +IH K   +K +K
Sbjct:  281 GCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEK 365

HSP 2 Score: 52.373 bits (124), Expect = 7.866e-7
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  303 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 359

[Close]

BLAST of EGR-1 vs. Ensembl Mouse
Match: Egr1 (early growth response 1 [Source:MGI Symbol;Acc:MGI:95295])

HSP 1 Score: 106.686 bits (265), Expect = 3.594e-24
Identity = 53/102 (51.96%), Postives = 67/102 (65.69%), Query Frame = 2

Query:  611 RISREEKSKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH
Sbjct:  315 KPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 416

[Close]

Query:  611 RISREEKSKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH
Sbjct:  315 KPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 416

[Close]

BLAST of EGR-1 vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 103.99 bits (258), Expect = 5.501e-24
Identity = 49/85 (57.65%), Postives = 59/85 (69.41%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
             C  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP++CE C + FARSDER RH +IH K   +K +K
Sbjct:  243 GCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKSEK 327

HSP 2 Score: 51.6026 bits (122), Expect = 1.124e-6
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  265 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 321

[Close]

BLAST of EGR-1 vs. Ensembl Mouse
Match: Egr2 (early growth response 2 [Source:MGI Symbol;Acc:MGI:95296])

HSP 1 Score: 104.76 bits (260), Expect = 1.164e-23
Identity = 59/131 (45.04%), Postives = 74/131 (56.49%), Query Frame = 2

Query:  545 LDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            L  S  +  T     P H P+  I R  K  +  S     ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+ C + FARSDER RHT+IH +   RK
Sbjct:  294 LPGSGSAAVTATPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERK 424

[Close]

BLAST of EGR-1 vs. UniProt/SwissProt
Match: sp|P26632|EGR1_DANRE (Early growth response protein 1 OS=Danio rerio OX=7955 GN=egr1 PE=2 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 3.621e-24
Identity = 56/110 (50.91%), Postives = 70/110 (63.64%), Query Frame = 2

Query:  617 SREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            SR  K  +  S   P ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++CEIC + FARSDER RHT+IH +   +K +K
Sbjct:  292 SRMRKYPNRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQKDKKAEK 401

[Close]

BLAST of EGR-1 vs. UniProt/SwissProt
Match: sp|A4II20|EGR1_XENTR (Early growth response protein 1 OS=Xenopus tropicalis OX=8364 GN=egr1 PE=2 SV=2)

HSP 1 Score: 108.227 bits (269), Expect = 6.146e-24
Identity = 54/104 (51.92%), Postives = 68/104 (65.38%), Query Frame = 2

Query:  605 ISRISREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            I + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH
Sbjct:  284 IIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIH 387

[Close]

BLAST of EGR-1 vs. UniProt/SwissProt
Match: sp|Q6NTY6|EGR1B_XENLA (Early growth response protein 1-B OS=Xenopus laevis OX=8355 GN=egr1-b PE=2 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.028e-23
Identity = 56/114 (49.12%), Postives = 72/114 (63.16%), Query Frame = 2

Query:  605 ISRISREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            I + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH +   +K  K
Sbjct:  261 IIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK 374

[Close]

BLAST of EGR-1 vs. UniProt/SwissProt
Match: sp|Q6GQH4|EGR1A_XENLA (Early growth response protein 1-A OS=Xenopus laevis OX=8355 GN=egr1-a PE=2 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.128e-23
Identity = 56/114 (49.12%), Postives = 72/114 (63.16%), Query Frame = 2

Query:  605 ISRISREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            I + SR  K  +  S   P ++ + C   +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH +   +K  K
Sbjct:  283 IIKPSRMRKYPNRPSKTPPHERPYGCPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADK 396

[Close]

BLAST of EGR-1 vs. UniProt/SwissProt
Match: sp|O73693|EGR1_TAEGU (Early growth response protein 1 (Fragment) OS=Taeniopygia guttata OX=59729 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 1.816e-23
Identity = 49/84 (58.33%), Postives = 60/84 (71.43%), Query Frame = 2

Query:  689 CPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+IC + FARSDER RHT+IH +   +K +K
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKVEK 84

[Close]

BLAST of EGR-1 vs. TrEMBL
Match: H9CXV3 (EGR-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 700.279 bits (1806), Expect = 0.000e+0
Identity = 388/389 (99.74%), Postives = 388/389 (99.74%), Query Frame = 2

Query:  131 MILDETANDDPTDYVHNSSHNSSFEVHSKQFENLLSIPAYNDHCGFIQNMEFXXXXXXXXXXXXXXXXXXXXXXDHSNDLLQMLQNDPFISTDCRFITDSQSQYFHPYQQYMCRIAXXXXXXXXXYAIYDNSKLKPIPLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKAFIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID 1297
            MILDETANDDPTDYVHNSSHNSSFEVHSKQFENLLSIPAYNDHCGFIQNMEFNGGGYQYSSNNGNYSLLQQLNSDHSNDLLQMLQNDPFISTDCRFITDSQSQYFHPYQQYMCRIANNNFHNVNNYAIYDNSKLKPIPLDSSQISNQTNIKLEPLHDPIS ISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPNANNNTSNNDYTKSAIIDLDSLKSNLPLVQNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKAFIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID
Sbjct:    1 MILDETANDDPTDYVHNSSHNSSFEVHSKQFENLLSIPAYNDHCGFIQNMEFNGGGYQYSSNNGNYSLLQQLNSDHSNDLLQMLQNDPFISTDCRFITDSQSQYFHPYQQYMCRIANNNFHNVNNYAIYDNSKLKPIPLDSSQISNQTNIKLEPLHDPISTISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPNANNNTSNNDYTKSAIIDLDSLKSNLPLVQNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKAFIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID 389

[Close]

BLAST of EGR-1 vs. TrEMBL
Match: I1ZI72 (Early growth response-4 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 1.454e-32
Identity = 67/130 (51.54%), Postives = 92/130 (70.77%), Query Frame = 2

Query:  542 PLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            P++ S I N+ + +    +  + + + EEK+      +   +++F C  CP++F+R+DEL+RHEKIH+G K L CPYCDK F+RSDHR THIRTHTGEKPYSC+IC K FARSDE+ RH RIH K+  +K
Sbjct:  155 PIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 284

[Close]

BLAST of EGR-1 vs. TrEMBL
Match: A0A0B7BZD2 (Uncharacterized protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF216007 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 8.005e-27
Identity = 61/140 (43.57%), Postives = 89/140 (63.57%), Query Frame = 2

Query:  644 KSNQLPP-DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPFVE 1054
            + +++PP ++ ++C   NC  RF+R DEL RH +IHTG K   CP C ++F RSDH  TH RTHTGEKP+SC+IC + FARSDE+ RH ++H K  ++K  K      +     + S +  LD++ S +PLV +   FV+
Sbjct:  143 RPSKIPPHERPYSCLVENCDRRFSRSDELTRHMRIHTGQKPFPCPICGRSFSRSDHLTTHKRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKDAK---LVTSQPVSASSSTMDSLDNIVSTIPLVVSSPSFVD 279

[Close]

BLAST of EGR-1 vs. TrEMBL
Match: A0A3Q3E8P3 (Uncharacterized protein OS=Labrus bergylta OX=56723 PE=4 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 3.430e-25
Identity = 64/137 (46.72%), Postives = 83/137 (60.58%), Query Frame = 2

Query:  530 LKPIPLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPP-DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            L  I   SSQI  Q++       D I++ SR  KS +G+  + PP ++ + C    C  RF+R DEL RH ++HTG K   C  C ++F RSDH  THIRTHTGEKP+SC  C + FARSDER RH +IH +   RK
Sbjct:   50 LSTIKAFSSQIQTQSHTP----QDQIAKTSRSRKSPAGRQCKTPPHERPYACPADGCDRRFSRSDELTRHVRVHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCGECGRKFARSDERKRHAKIHQRQRERK 182

[Close]

BLAST of EGR-1 vs. TrEMBL
Match: G1CSV5 (EGR-like protein 1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 1.114e-24
Identity = 55/118 (46.61%), Postives = 74/118 (62.71%), Query Frame = 2

Query:  551 SSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTR 904
            S++++  T   L  +  P+S IS + + +          K FTC+ C   F R+DEL+RHE+IHTG + L C +CDK F+RSDH  TH+R HTGEKPY C  C + F+RSDER RH R
Sbjct:   74 STKLNPNTKKSLRIISSPLSEISEKSQFRI---------KQFTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIHTGEKPYQCSYCDRLFSRSDERLRHIR 182

HSP 2 Score: 57.3806 bits (137), Expect = 7.547e-6
Identity = 28/63 (44.44%), Postives = 35/63 (55.56%), Query Frame = 2

Query:  731 EKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            EK    IK   C  C K+F R D  + H R HTGE+P +C  C K F RSD  + H RIH+ +
Sbjct:   97 EKSQFRIKQFTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIHTGE 159

[Close]

BLAST of EGR-1 vs. Ensembl Cavefish
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:103035480])

HSP 1 Score: 106.301 bits (264), Expect = 1.553e-24
Identity = 52/86 (60.47%), Postives = 61/86 (70.93%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKP 943
            NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SCE C + FARSDER RH ++H K   +K KKP
Sbjct:  308 NCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLK---QKDKKP 390

HSP 2 Score: 51.2174 bits (121), Expect = 1.513e-6
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  330 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 386

[Close]

BLAST of EGR-1 vs. Ensembl Cavefish
Match: egr4 (early growth response protein 1-B [Source:NCBI gene;Acc:103025429])

HSP 1 Score: 105.145 bits (261), Expect = 2.119e-24
Identity = 59/139 (42.45%), Postives = 80/139 (57.55%), Query Frame = 2

Query:  533 KPIPLDSSQISNQTNIKLEPLHDPISRISREEKSKSG-KSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            +P+ LDS  +S            P +  +   K+  G K+     +K F C   NC  RF+R DEL RH ++HTG +   C  C + F RSDH  TH+RTHTGEKP+SC++C + FARSDER RH R+H K   R ++K
Sbjct:  237 EPLTLDSLLLSGAL---------PATNRAHAPKATGGRKAAGARREKPFPCPVENCERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHIKQRERAQQK 366

[Close]

BLAST of EGR-1 vs. Ensembl Cavefish
Match: egr4 (early growth response protein 1-B [Source:NCBI gene;Acc:103025429])

HSP 1 Score: 104.375 bits (259), Expect = 2.782e-24
Identity = 50/94 (53.19%), Postives = 64/94 (68.09%), Query Frame = 2

Query:  665 DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            +K F C   NC  RF+R DEL RH ++HTG +   C  C + F RSDH  TH+RTHTGEKP+SC++C + FARSDER RH R+H K   R ++K
Sbjct:  234 EKPFPCPVENCERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHIKQRERAQQK 327

[Close]

BLAST of EGR-1 vs. Ensembl Cavefish
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:103036296])

HSP 1 Score: 105.531 bits (262), Expect = 6.256e-24
Identity = 51/92 (55.43%), Postives = 64/92 (69.57%), Query Frame = 2

Query:  644 KSNQLPP-DKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            + ++ PP ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++CEIC + FARSDER RHT+IH
Sbjct:  307 RPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIH 398

[Close]

BLAST of EGR-1 vs. Ensembl Cavefish
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:103046494])

HSP 1 Score: 101.293 bits (251), Expect = 6.576e-23
Identity = 48/82 (58.54%), Postives = 57/82 (69.51%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
             C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+ C + FARSDER RHT+IH +   RK
Sbjct:  302 GCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERK 383

[Close]

BLAST of EGR-1 vs. Ensembl Sea Lamprey
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 99.3673 bits (246), Expect = 9.828e-24
Identity = 48/86 (55.81%), Postives = 58/86 (67.44%), Query Frame = 2

Query:  668 KSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            + F C    C  RF+R DEL RH +IHTG K   C  C ++F RSDH  TH+RTHTGEKP++C+ C + FARSDER RH RIH K 
Sbjct:  170 RPFPCPAEGCDRRFSRTDELTRHIRIHTGHKPFTCRICMRSFSRSDHLTTHVRTHTGEKPFACDFCGRRFARSDERKRHGRIHLKG 255

[Close]

BLAST of EGR-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005004.1 (pep scaffold:Pmarinus_7.0:GL484587:30140:35096:1 gene:ENSPMAG00000004537.1 transcript:ENSPMAT00000005004.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.9593 bits (206), Expect = 1.094e-17
Identity = 41/117 (35.04%), Postives = 68/117 (58.12%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKS 1015
            +K++ CS C  RF +K  L+RHEKIH+G K   C  C   FI+  H   H RTH+GEKPY C+ C + ++R+D+  +H R+  + P+  +      ++ +  D+T      +D+L++
Sbjct:   31 EKAYQCSQCTMRFIQKYLLQRHEKIHSGEKPFTCEQCGMRFIQKYHLERHKRTHSGEKPYECDYCHQYYSRTDQLAKHKRMCHEGPLAGK------HDMNAGDFTAGINGGMDALQA 141

HSP 2 Score: 61.2326 bits (147), Expect = 2.135e-10
Identity = 32/84 (38.10%), Postives = 42/84 (50.00%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            K F C  C + F     L+RH  IHTG K   C  C   FI+    + H + H+GEKP++CE C   F +     RH R HS +
Sbjct:    4 KKFVCERCCAAFRTNYHLQRHVLIHTGEKAYQCSQCTMRFIQKYLLQRHEKIHSGEKPFTCEQCGMRFIQKYHLERHKRTHSGE 87

[Close]

BLAST of EGR-1 vs. Ensembl Sea Lamprey
Match: wt1a (WT1 transcription factor a [Source:ZFIN;Acc:ZDB-GENE-980526-558])

HSP 1 Score: 78.5666 bits (192), Expect = 1.826e-16
Identity = 42/86 (48.84%), Postives = 55/86 (63.95%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGI---KTLCCPYCDKTFIRSDHRRTHIRTHTG---EKPYSCEI--CCKCFARSDERTRHTRIHSKD 919
            +C  RF+R D+L+RH++ HTG+   K   C  CD+ F RSDH +TH RTHTG   EKP+ C    C K FARSDE  RH  +H ++
Sbjct:  207 DCGRRFSRSDQLKRHQRRHTGVTGVKPFQCKMCDRKFARSDHLKTHTRTHTGKPSEKPFVCRWPNCQKKFARSDELVRHHNMHQRN 292

HSP 2 Score: 57.7658 bits (138), Expect = 1.711e-9
Identity = 38/107 (35.51%), Postives = 56/107 (52.34%), Query Frame = 2

Query:  632 SKSGKSNQLPPDKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPY--CDKTFIRSDHRRTHIRTHTGE---KPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            S  G++++ P    + C+   C  R+ +   L+ H + HTG +   C Y  C + F RSD  + H R HTG    KP+ C++C + FARSD    HTR H+  P  K
Sbjct:  161 SGRGRADRRP----YMCNYPGCSKRYFKLSHLQMHCRKHTGERPYQCDYKDCGRRFSRSDQLKRHQRRHTGVTGVKPFQCKMCDRKFARSDHLKTHTRTHTGKPSEK 263

[Close]

BLAST of EGR-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000923.1 (pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 gene:ENSPMAG00000000839.1 transcript:ENSPMAT00000000923.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.633 bits (174), Expect = 1.117e-15
Identity = 30/80 (37.50%), Postives = 43/80 (53.75%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTR 904
            ++ + C +C  RF R     RH ++HTG +   C  C + F +  H   H R HTGE+PY+C  C + FA+    TRH R
Sbjct:   19 ERPYACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHTGERPYACAACGRRFAKPYSLTRHLR 98

HSP 2 Score: 51.6026 bits (122), Expect = 9.638e-9
Identity = 22/58 (37.93%), Postives = 31/58 (53.45%), Query Frame = 2

Query:  740 HTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            HTG +   C  C + F R  +   H R HTGE+PY+C  C + F +      HTR+H+
Sbjct:   16 HTGERPYACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHT 73

HSP 3 Score: 43.1282 bits (100), Expect = 9.085e-6
Identity = 17/35 (48.57%), Postives = 24/35 (68.57%), Query Frame = 2

Query:  809 THIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            ++IR HTGE+PY+C  C + FAR     RH R+H+
Sbjct:   11 SNIRNHTGERPYACGDCGRRFARGANEERHRRVHT 45

[Close]

BLAST of EGR-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004792.1 (pep scaffold:Pmarinus_7.0:GL479046:11287:22931:1 gene:ENSPMAG00000004344.1 transcript:ENSPMAT00000004792.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.7146 bits (182), Expect = 1.465e-15
Identity = 35/81 (43.21%), Postives = 49/81 (60.49%), Query Frame = 2

Query:  677 TCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            TC+   +R +   E  RH +IH G++   C  CDK F + +  +TH+R HTGEKPY CE+C K FA+  +   HTR+H  D
Sbjct:   20 TCACVVTRSSSHAEPLRHARIHKGLRPFICSLCDKAFTQGNQLKTHMRIHTGEKPYVCEVCGKAFAQKCQLVFHTRMHHGD 100

HSP 2 Score: 58.5362 bits (140), Expect = 4.555e-10
Identity = 44/130 (33.85%), Postives = 60/130 (46.15%), Query Frame = 2

Query:  524 SKLKPIPLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTG-EKPYSCEICCKCFARSDERTRHTRIH 910
            S+ KP+    + +  +++   EPL     R +R  K        L P   F CS C   FT+ ++L+ H +IHTG K   C  C K F +      H R H G EKPY C++C   FA S     H R H
Sbjct:   12 SRRKPVCQTCACVVTRSSSHAEPL-----RHARIHKG-------LRP---FICSLCDKAFTQGNQLKTHMRIHTGEKPYVCEVCGKAFAQKCQLVFHTRMHHGDEKPYGCDVCGLRFATSSNLKIHVRKH 126

HSP 3 Score: 55.4546 bits (132), Expect = 4.847e-9
Identity = 34/113 (30.09%), Postives = 46/113 (40.71%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCP----------------------------YCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            +K + C  C  RF     L+ H + H  +  L CP                            +C   F++S    TH R HTGEKPY C  C KCF  S E  +H+R H+ +
Sbjct:  101 EKPYGCDVCGLRFATSSNLKIHVRKHRDVNNLACPVQGNGPSRHHHHYRPVKRHQGHVNWAANFCSIFFLQSSSLITHARKHTGEKPYICNTCGKCFCSSGELKKHSRSHTGE 213

HSP 4 Score: 47.7506 bits (112), Expect = 1.972e-6
Identity = 24/57 (42.11%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  689 CPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEIC 859
            C   F +   L  H + HTG K   C  C K F  S   + H R+HTGE+P+ CEIC
Sbjct:  165 CSIFFLQSSSLITHARKHTGEKPYICNTCGKCFCSSGELKKHSRSHTGERPFICEIC 221

[Close]

BLAST of EGR-1 vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 74.3294 bits (181), Expect = 1.757e-14
Identity = 41/123 (33.33%), Postives = 59/123 (47.97%), Query Frame = 2

Query:  548 DSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSK 916
            D   + NQT   L P  + +  + + + +++ ++      K   C  C   F++   L  H + H G K   C YC K F +  + RTH R HTGEKPYSC+IC K F+R      H   H K
Sbjct:  556 DGDLLFNQTMDILPPKSELVGGVEKPKGTQNTRA-----VKKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQK 673

HSP 2 Score: 65.855 bits (159), Expect = 6.835e-12
Identity = 32/84 (38.10%), Postives = 43/84 (51.19%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEI--CCKCFAR-SDERTRHTRIH 910
            K F C  C  RFT+   LR HE++HTG K   C  CDK F R  +   H+ TH   KP+ C++  C K F +  + +    R H
Sbjct:  619 KPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFH 702

[Close]

BLAST of EGR-1 vs. Ensembl Yeast
Match: MIG1 (Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state [Source:SGD;Acc:S000003003])

HSP 1 Score: 69.707 bits (169), Expect = 2.816e-13
Identity = 38/96 (39.58%), Postives = 56/96 (58.33%), Query Frame = 2

Query:  761 CCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEI--CCKCFARSDERTRHTRIHSKD---PVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQ 1033
             CP C + F R +H+  H+R HTGEKP++C+   C K F+RSDE TRH RIH+       R RKK    +  ++   + ++I DL++   + PL Q
Sbjct:   39 ACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHPRGKRGRKKKVVGSPINSASSSATSIPDLNTANFSPPLPQ 134

[Close]

BLAST of EGR-1 vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 67.3958 bits (163), Expect = 2.434e-12
Identity = 33/83 (39.76%), Postives = 46/83 (55.42%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSK 916
            K + C  C   F+ ++ L +H + H+G K   C  C+K F  S   + HIRTHTGEKP  C+IC K F  S   ++H + H K
Sbjct:  766 KPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQK 848

HSP 2 Score: 57.3806 bits (137), Expect = 2.946e-9
Identity = 30/78 (38.46%), Postives = 41/78 (52.56%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            +C   F ++ +L RH K+H+  K   C  C + F   +    H RTH+GEKPY C IC K FA S     H R H+ +
Sbjct:  744 DCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGE 821

[Close]

BLAST of EGR-1 vs. Ensembl Yeast
Match: MIG3 (Transcriptional regulator; partially nonfunctional in S288C strains but has a major role in catabolite repression and ethanol response in some other strains; involved in response to toxic agents; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genesenvironment [Source:SGD;Acc:S000000830])

HSP 1 Score: 63.1586 bits (152), Expect = 2.863e-11
Identity = 30/61 (49.18%), Postives = 39/61 (63.93%), Query Frame = 2

Query:  764 CPYCDKTFIRSDHRRTHIRTHTGEKPYSCEI--CCKCFARSDERTRHTRIHSKDPVRKRKK 940
            C  C + F R +H++ H RTHTGEKP+ C +  C K F+RSDE  RH R H+K   R+R K
Sbjct:   19 CEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHTKGVQRRRIK 79

[Close]

BLAST of EGR-1 vs. Ensembl Yeast
Match: MIG2 (Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced gene repression; under low glucose conditions relocalizes to mitochondrion, where it interacts with Ups1p, antagonizes mitochondrial fission factor Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth in response to glucose depletion; activated in stochastic pulses of nuclear localization in response to low glucose [Source:SGD;Acc:S000003177])

HSP 1 Score: 62.7734 bits (151), Expect = 3.150e-11
Identity = 29/61 (47.54%), Postives = 38/61 (62.30%), Query Frame = 2

Query:  764 CPYCDKTFIRSDHRRTHIRTHTGEKPYSCEI--CCKCFARSDERTRHTRIHSKDPVRKRKK 940
            C  C + F R +H++ H+RTHTGEKP+ C    C K F+RSDE  RH R H+    R+ KK
Sbjct:   19 CDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQSQRRLKK 79

HSP 2 Score: 51.2174 bits (121), Expect = 1.792e-7
Identity = 25/59 (42.37%), Postives = 34/59 (57.63%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCC--PYCDKTFIRSDHRRTHIRTHTGE 835
            ++ F C  C   F R +  +RH + HTG K   C  P C K+F RSD  + H+RTHTG+
Sbjct:   14 NRPFRCDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQ 72

[Close]

BLAST of EGR-1 vs. Ensembl Nematostella
Match: EDO49112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGT8])

HSP 1 Score: 93.9745 bits (232), Expect = 1.383e-23
Identity = 46/78 (58.97%), Postives = 55/78 (70.51%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
             CP RF+R DEL RH + HTG K   C  C + F RSDH  THIRTHTGEKP++CE C + FARSDER RH +IH ++
Sbjct:   10 TCPRRFSRSDELTRHMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHLRE 87

[Close]

BLAST of EGR-1 vs. Ensembl Nematostella
Match: EDO29702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2W2])

HSP 1 Score: 78.1814 bits (191), Expect = 2.648e-16
Identity = 38/82 (46.34%), Postives = 50/82 (60.98%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   F +  +L+RH KIHTG K   C  C K F RS+  +TH+R H+G+KPY C++C KCF+ S    RH  IHS
Sbjct:   90 KPYKCDECGKCFIQYVDLKRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHS 171

HSP 2 Score: 70.0922 bits (170), Expect = 1.448e-13
Identity = 33/82 (40.24%), Postives = 47/82 (57.32%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   FTR + L+ H +IH+G K   C  C K F  S + + H+  H+G+KPY C++C KCF+ S    +H  IHS
Sbjct:  118 KPYECGECGKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHS 199

HSP 3 Score: 69.707 bits (169), Expect = 2.267e-13
Identity = 34/82 (41.46%), Postives = 49/82 (59.76%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   FT+   L RH +IH+G K   C  C K F +S + +TH+R H+G+KPY C+ C KCF +  +  RH +IH+
Sbjct:   34 KPYRCDECGKGFTQSGALNRHLRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHT 115

HSP 4 Score: 68.1662 bits (165), Expect = 7.761e-13
Identity = 43/123 (34.96%), Postives = 57/123 (46.34%), Query Frame = 2

Query:  680 CSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPF 1048
            C  C   FTR   L+RH  IH+G K   C  C K F +S     H+R H+G+KPY C+ C KCF +S     H RIHS       +KP         D      I    LK +L +   ++P+
Sbjct:   10 CGECGMGFTRHAYLKRHLMIHSGQKPYRCDECGKGFTQSGALNRHLRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSG------QKP------YKCDECGKCFIQYVDLKRHLKIHTGQKPY 120

HSP 5 Score: 67.0106 bits (162), Expect = 1.914e-12
Identity = 34/82 (41.46%), Postives = 45/82 (54.88%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   F +   L+ H +IH+G K   C  C K FI+    + H++ HTG+KPY C  C KCF RS+    H RIHS
Sbjct:   62 KPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIHS 143

HSP 6 Score: 54.299 bits (129), Expect = 2.553e-8
Identity = 27/68 (39.71%), Postives = 37/68 (54.41%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCF 871
            K + C  C   F+    L+RH  IH+G K   C  C K F  S + + H+  H+G+KPY C+ C KCF
Sbjct:  146 KPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCF 213

HSP 7 Score: 48.1358 bits (113), Expect = 2.759e-6
Identity = 27/74 (36.49%), Postives = 40/74 (54.05%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRT---HIRTHTGEKPYSCEICCKCFARS 880
            K + C  C   F+    L++H  IH+G K   C  C K FI   + +T   H+  H+G+KP+ C+ C KCF +S
Sbjct:  174 KPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCFILYRNLKTHLIHLMIHSGQKPHKCDECGKCFHQS 247

[Close]

BLAST of EGR-1 vs. Ensembl Nematostella
Match: EDO38793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBW1])

HSP 1 Score: 72.0182 bits (175), Expect = 1.789e-15
Identity = 33/84 (39.29%), Postives = 49/84 (58.33%), Query Frame = 2

Query:  656 LPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRI 907
            L P+K + C  C   F+  +ELR H  +H   K   C YC ++F  +     HIRTHTGEKP+ CE C K F+++ + ++H +I
Sbjct:   22 LVPNKPYHCGYCSESFSNPNELRNHSIVHANEKPFRCGYCSRSFSGATTLNNHIRTHTGEKPFMCEACGKTFSQASQLSKHQKI 105

[Close]

BLAST of EGR-1 vs. Ensembl Nematostella
Match: EDO43177 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ64])

HSP 1 Score: 73.559 bits (179), Expect = 2.330e-15
Identity = 43/125 (34.40%), Postives = 63/125 (50.40%), Query Frame = 2

Query:  545 LDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
               S +S + N+ ++  HD       EE           PD S TC  C   ++R   L+ H ++HTG K   CP C K+F +  + + H+R H+ EKP+ C IC + FA+S   T H RIHS +
Sbjct:    2 FQGSDMSYRNNVAVQNNHDGRMEDHLEE-----------PDYSITCHVCHKIYSRPSTLKAHLRVHTGKKPFRCPTCQKSFSQDANLKAHLRVHSKEKPFKCHICHRRFAQSSSVTTHMRIHSGE 115

HSP 2 Score: 63.5438 bits (153), Expect = 5.726e-12
Identity = 33/84 (39.29%), Postives = 45/84 (53.57%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSK 916
            +K F C  C  RF +   +  H +IH+G +   C  C + F  S      +RTHTGEKPY C IC   F++S   +RH RI+ K
Sbjct:   87 EKPFKCHICHRRFAQSSSVTTHMRIHSGERPYKCKVCARGFSDSSTLTKRLRTHTGEKPYQCRICGMSFSQSGNLSRHMRIYRK 170

[Close]

BLAST of EGR-1 vs. Ensembl Nematostella
Match: EDO31838 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWT3])

HSP 1 Score: 77.0258 bits (188), Expect = 4.093e-15
Identity = 39/84 (46.43%), Postives = 49/84 (58.33%), Query Frame = 2

Query:  662 PDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            P K   C  C   F +   L+RH KIHTG K   C  C K F RS+  +TH+R H+G+KPY C++C KCF+ S    RH  IHS
Sbjct:  342 PYKPHKCDECGKCFNQSGHLKRHLKIHTGQKPYECGECSKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHS 425

HSP 2 Score: 73.1738 bits (178), Expect = 5.941e-14
Identity = 35/85 (41.18%), Postives = 51/85 (60.00%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            +K + C +C  RFT    ++ H +IH+G K   C  C K F  S + +TH+  H+GEKPY C+ C KCF +S +  RH RIH+ +
Sbjct:  116 EKPYECDDCGKRFTLSGNMKTHLRIHSGKKPYKCDECGKCFTESGNLKTHLMIHSGEKPYKCDECGKCFTQSGDLKRHLRIHTGE 200

HSP 3 Score: 70.8626 bits (172), Expect = 3.592e-13
Identity = 37/85 (43.53%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            +K   C +C  RFTR  +L+ H +IHTG K   C  C K F  S + +TH+R H+G+KPY C+ C KCF  S     H  IHS +
Sbjct:   88 EKPHKCDDCGKRFTRSGDLKTHLRIHTGEKPYECDDCGKRFTLSGNMKTHLRIHSGKKPYKCDECGKCFTESGNLKTHLMIHSGE 172

HSP 4 Score: 68.5514 bits (166), Expect = 1.928e-12
Identity = 46/127 (36.22%), Postives = 61/127 (48.03%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPF 1048
            K + C  C   F+   +L+RH  IHTG K   C  C K F RS   +TH+R HTGEKPY C+ C K F  S     H RIHS       KKP         D       +  +LK++L +   ++P+
Sbjct:   61 KPYKCDECGKCFSESGKLKRHLMIHTGEKPHKCDDCGKRFTRSGDLKTHLRIHTGEKPYECDDCGKRFTLSGNMKTHLRIHSG------KKP------YKCDECGKCFTESGNLKTHLMIHSGEKPY 175

HSP 5 Score: 67.781 bits (164), Expect = 3.578e-12
Identity = 33/82 (40.24%), Postives = 47/82 (57.32%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   FTR + L+ H +IH+G K   C  C K F  S + + H+  H+G+KPY C++C KCF+ S    +H  IHS
Sbjct:  372 KPYECGECSKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHS 453

HSP 6 Score: 67.0106 bits (162), Expect = 6.697e-12
Identity = 34/82 (41.46%), Postives = 46/82 (56.10%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   FT  + L+ H  IH+G K   C  C K F +S + + H+  H+G+KPY C++C KCF RS   T H  IHS
Sbjct:  257 KPYKCDECGKCFTELETLKTHLMIHSGEKPYKCDECGKCFTQSGNLKRHLMIHSGQKPYKCDVCGKCFTRSGALTTHLMIHS 338

HSP 7 Score: 66.6254 bits (161), Expect = 8.650e-12
Identity = 35/84 (41.67%), Postives = 48/84 (57.14%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            K + C  C   FTR  +L+ H  IH+G K   C  C K F  + H  TH+R H+G+KPY C+ C KCF+ S +  RH  IH+ +
Sbjct:    7 KRYNCDECGKCFTRHAQLKEHLVIHSGKKPYKCDECGKCF--TQHANTHLRIHSGKKPYKCDECGKCFSESGKLKRHLMIHTGE 88

HSP 8 Score: 64.3142 bits (155), Expect = 4.496e-11
Identity = 35/86 (40.70%), Postives = 47/86 (54.65%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPY---SCEICCKCFARSDERTRHTRIHS 913
            +K + C  C   FT+   L+RH  IH+G K   C  C K F RS    TH+  H+G+KPY    C+ C KCF +S    RH +IH+
Sbjct:  284 EKPYKCDECGKCFTQSGNLKRHLMIHSGQKPYKCDVCGKCFTRSGALTTHLMIHSGQKPYKPHKCDECGKCFNQSGHLKRHLKIHT 369

HSP 9 Score: 64.3142 bits (155), Expect = 4.699e-11
Identity = 32/85 (37.65%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            +K + C +C  RFT    +++H KIH+G K   C  C K+F    + +TH+  H+G+KPY C+ C KCF   +    H  IHS +
Sbjct:  200 EKPYECDDCGKRFTLSGNMKKHLKIHSGKKPYKCDECGKSFTEHAYLKTHLIIHSGKKPYKCDECGKCFTELETLKTHLMIHSGE 284

HSP 10 Score: 63.1586 bits (152), Expect = 9.586e-11
Identity = 41/128 (32.03%), Postives = 63/128 (49.22%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPF 1048
            +K + C  C   FT+  +L+RH +IHTG K   C  C K F  S + + H++ H+G+KPY C+ C K F        H  IHS       KKP         D       +L++LK++L +   ++P+
Sbjct:  172 EKPYKCDECGKCFTQSGDLKRHLRIHTGEKPYECDDCGKRFTLSGNMKKHLKIHSGKKPYKCDECGKSFTEHAYLKTHLIIHSG------KKP------YKCDECGKCFTELETLKTHLMIHSGEKPY 287

HSP 11 Score: 62.7734 bits (151), Expect = 1.259e-10
Identity = 43/127 (33.86%), Postives = 59/127 (46.46%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPF 1048
            K + C  C   FT    L+ H  IH+G K   C  C K F +S   + H+R HTGEKPY C+ C K F  S    +H +IHS       KKP         D    +  +   LK++L +   K+P+
Sbjct:  145 KPYKCDECGKCFTESGNLKTHLMIHSGEKPYKCDECGKCFTQSGDLKRHLRIHTGEKPYECDDCGKRFTLSGNMKKHLKIHSG------KKP------YKCDECGKSFTEHAYLKTHLIIHSGKKPY 259

HSP 12 Score: 62.3882 bits (150), Expect = 1.654e-10
Identity = 34/82 (41.46%), Postives = 43/82 (52.44%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHS 913
            K + C  C   FT    L+ H  IH+G K   C  C K F   +  +TH+  H+GEKPY C+ C KCF +S    RH  IHS
Sbjct:  229 KPYKCDECGKSFTEHAYLKTHLIIHSGKKPYKCDECGKCFTELETLKTHLMIHSGEKPYKCDECGKCFTQSGNLKRHLMIHS 310

HSP 13 Score: 55.4546 bits (132), Expect = 2.522e-8
Identity = 31/83 (37.35%), Postives = 42/83 (50.60%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSK 916
            K + C  C   F+    L+RH  IH+G K   C  C K F  S + + H+  H+G+KPY C+ C KCF        H  IHS+
Sbjct:  400 KPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCFILYRNLKTHLSIHSR 482

HSP 14 Score: 52.373 bits (124), Expect = 2.603e-7
Identity = 32/84 (38.10%), Postives = 43/84 (51.19%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            K + C  C   FT+      H +IH+G K   C  C K F  S   + H+  HTGEKP+ C+ C K F RS +   H RIH+ +
Sbjct:   35 KPYKCDECGKCFTQ--HANTHLRIHSGKKPYKCDECGKCFSESGKLKRHLMIHTGEKPHKCDDCGKRFTRSGDLKTHLRIHTGE 116

[Close]

BLAST of EGR-1 vs. Ensembl Medaka
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100272163])

HSP 1 Score: 108.227 bits (269), Expect = 8.336e-25
Identity = 56/110 (50.91%), Postives = 70/110 (63.64%), Query Frame = 2

Query:  617 SREEKSKSGKSNQLPPDKSFTC--SNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            SR  K  +  S   P ++ + C    C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++CEIC + FARSDER RHT+IH +   +K +K
Sbjct:  294 SRMRKYPTRPSKTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHLRQKDKKAEK 403

[Close]

BLAST of EGR-1 vs. Ensembl Medaka
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:100272164])

HSP 1 Score: 105.145 bits (261), Expect = 3.199e-24
Identity = 49/85 (57.65%), Postives = 60/85 (70.59%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            NC  RF+R DEL RH +IHTG K   C  C ++F RSDH  THIRTHTGEKP+SCE C + FARSDER RH ++H K   +K+ +
Sbjct:  302 NCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKDKKQAE 386

HSP 2 Score: 51.2174 bits (121), Expect = 1.417e-6
Identity = 23/57 (40.35%), Postives = 30/57 (52.63%), Query Frame = 2

Query:  668 KSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEK 838
            K F C  C   F+R D L  H + HTG K   C +C + F RSD R+ H + H  +K
Sbjct:  324 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 380

[Close]

BLAST of EGR-1 vs. Ensembl Medaka
Match: ENSORLT00000000940.2 (early growth response protein 1 [Source:NCBI gene;Acc:101160576])

HSP 1 Score: 103.99 bits (258), Expect = 1.352e-23
Identity = 58/132 (43.94%), Postives = 77/132 (58.33%), Query Frame = 2

Query:  551 SSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPP-DKSFTCS--NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRK 937
            S+QI  Q    L      +++  + +KS  G+  + PP ++   C    C  RF+R DEL RH ++HTG K   C  C ++F RSDH  THIRTHTGEKP+ C  C + FARSDER RH +IH +   R RK
Sbjct:  247 SAQIQPQGPGGL------LAKSCQSKKSPGGRQCRTPPHERPHVCPADGCERRFSRSDELTRHVRVHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFPCSECGRKFARSDERKRHAKIHQRQ--RDRK 370

[Close]

BLAST of EGR-1 vs. Ensembl Medaka
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:101170128])

HSP 1 Score: 100.908 bits (250), Expect = 1.248e-22
Identity = 48/82 (58.54%), Postives = 57/82 (69.51%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
             C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP++C+ C + FARSDER RHT+IH +   RK
Sbjct:  336 GCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERK 417

[Close]

BLAST of EGR-1 vs. Ensembl Medaka
Match: ENSORLT00000034291.1 (early growth response protein 2b [Source:NCBI gene;Acc:101164744])

HSP 1 Score: 98.5969 bits (244), Expect = 4.770e-22
Identity = 48/85 (56.47%), Postives = 60/85 (70.59%), Query Frame = 2

Query:  686 NCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKK 940
            +C  RF+R DEL RH +IHTG K   C  C + F RSDH  THIRTHTGEKP+SC+ C + FARSDER RH +IH    +R+++K
Sbjct:  310 SCDRRFSRSDELSRHLRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFSCQQCGRKFARSDERRRHMKIH----LRQKEK 390

[Close]

BLAST of EGR-1 vs. Planmine SMEST
Match: SMESG000034285.1 (SMESG000034285.1)

HSP 1 Score: 688.723 bits (1776), Expect = 0.000e+0
Identity = 384/389 (98.71%), Postives = 384/389 (98.71%), Query Frame = 2

Query:  131 MILDETANDDPTDYVHNSSHNSSFEVHSKQFENLLSIPAYNDHCGFIQNMEFXXXXXXXXXXXXXXXXXXXXXXDHSNDLLQMLQNDPFISTDCRFITDSQSQYFHPYQQYMCRIAXXXXXXXXXYAIYDNSKLKPIPLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPXXXXXXXXXDYTKSAIIDLDSLKSNLPLVQNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKAFIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID 1297
            MILDE ANDDPTDYVHNSSHNSS EVHSKQFENLLSIPAYNDHC FIQNMEFNGGGYQYSSNNGNYSLLQQLNSDHSNDLLQMLQNDPFISTDCRFITDSQSQYFHPYQQYMCRIANNNFHNVNNYAIYDNSKLKPIPLDSSQISNQTNIKLE LHDPIS ISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPNANNNTSNNDYTKSAIIDLDSLKSNLPLVQNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKAFIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID
Sbjct:    1 MILDENANDDPTDYVHNSSHNSSCEVHSKQFENLLSIPAYNDHCEFIQNMEFNGGGYQYSSNNGNYSLLQQLNSDHSNDLLQMLQNDPFISTDCRFITDSQSQYFHPYQQYMCRIANNNFHNVNNYAIYDNSKLKPIPLDSSQISNQTNIKLEALHDPISTISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRKRKKPNANNNTSNNDYTKSAIIDLDSLKSNLPLVQNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKAFIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID 389

[Close]

BLAST of EGR-1 vs. Planmine SMEST
Match: SMESG000028801.1 (SMESG000028801.1)

HSP 1 Score: 135.961 bits (341), Expect = 4.374e-36
Identity = 67/130 (51.54%), Postives = 92/130 (70.77%), Query Frame = 2

Query:  542 PLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            P++ S I N+ + +    +  + + + EEK+      +   +++F C  CP++F+R+DEL+RHEKIH+G K L CPYCDK F+RSDHR THIRTHTGEKPYSC+IC K FARSDE+ RH RIH K+  +K
Sbjct:  134 PIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 263

[Close]

BLAST of EGR-1 vs. Planmine SMEST
Match: SMESG000028801.1 (SMESG000028801.1)

HSP 1 Score: 136.346 bits (342), Expect = 6.680e-36
Identity = 67/130 (51.54%), Postives = 92/130 (70.77%), Query Frame = 2

Query:  542 PLDSSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 931
            P++ S I N+ + +    +  + + + EEK+      +   +++F C  CP++F+R+DEL+RHEKIH+G K L CPYCDK F+RSDHR THIRTHTGEKPYSC+IC K FARSDE+ RH RIH K+  +K
Sbjct:  159 PIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 288

[Close]

BLAST of EGR-1 vs. Planmine SMEST
Match: SMESG000042500.1 (SMESG000042500.1)

HSP 1 Score: 138.272 bits (347), Expect = 6.978e-36
Identity = 60/82 (73.17%), Postives = 70/82 (85.37%), Query Frame = 2

Query:  665 DKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIH 910
            +K+F CS C  +FTR+DELRRHEKIH+G K L CPYCDK FIRSDHR+THIRTHTGEKPY+C+IC K FARSDE+ RHT+ H
Sbjct:  265 EKTFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTH 346

HSP 2 Score: 67.0106 bits (162), Expect = 1.007e-11
Identity = 31/69 (44.93%), Postives = 39/69 (56.52%), Query Frame = 2

Query:  713 DELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            D+  + +K+    KT CC  CD  F R D  R H + H+GEKP SC  C KCF RSD R  H R H+ +
Sbjct:  253 DKPVKTKKVVQTEKTFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGE 321

[Close]

BLAST of EGR-1 vs. Planmine SMEST
Match: SMESG000000960.1 (SMESG000000960.1)

HSP 1 Score: 110.923 bits (276), Expect = 3.097e-28
Identity = 55/118 (46.61%), Postives = 74/118 (62.71%), Query Frame = 2

Query:  551 SSQISNQTNIKLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTR 904
            S++++  T   L  +  P+S IS + + +          K FTC+ C   F R+DEL+RHE+IHTG + L C +CDK F+RSDH  TH+R HTGEKPY C  C + F+RSDER RH R
Sbjct:   74 STKLNPNTKKSLRIISSPLSEISEKSQFRI---------KQFTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIHTGEKPYQCSYCDRLFSRSDERLRHIR 182

HSP 2 Score: 57.3806 bits (137), Expect = 2.099e-9
Identity = 28/63 (44.44%), Postives = 35/63 (55.56%), Query Frame = 2

Query:  731 EKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKD 919
            EK    IK   C  C K+F R D  + H R HTGE+P +C  C K F RSD  + H RIH+ +
Sbjct:   97 EKSQFRIKQFTCNTCKKSFYRRDELKRHERIHTGERPLACHFCDKRFMRSDHLSTHVRIHTGE 159

The following BLAST results are available for this feature:

BLAST of EGR-1 vs. Ensembl Human
BLAST of EGR-1 vs. Ensembl Celegans
BLAST of EGR-1 vs. Ensembl Fly
BLAST of EGR-1 vs. Ensembl Zebrafish
BLAST of EGR-1 vs. Ensembl Xenopus
BLAST of EGR-1 vs. Ensembl Mouse
BLAST of EGR-1 vs. UniProt/SwissProt
BLAST of EGR-1 vs. TrEMBL
BLAST of EGR-1 vs. Ensembl Cavefish
BLAST of EGR-1 vs. Ensembl Sea Lamprey
BLAST of EGR-1 vs. Ensembl Yeast
BLAST of EGR-1 vs. Ensembl Nematostella
BLAST of EGR-1 vs. Ensembl Medaka
BLAST of EGR-1 vs. Planmine SMEST

BLAST of EGR-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EGR3	4.318e-24	57.65	early growth response 3 [Source:HGNC Symbol;Acc:HG...	[more]
EGR1	4.699e-24	51.96	early growth response 1 [Source:HGNC Symbol;Acc:HG...	[more]
EGR3	8.407e-24	57.65	early growth response 3 [Source:HGNC Symbol;Acc:HG...	[more]
EGR2	4.319e-23	47.50	early growth response 2 [Source:HGNC Symbol;Acc:HG...	[more]
EGR2	4.319e-23	47.50	early growth response 2 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of EGR-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egrh-2	1.267e-25	59.30	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	1.565e-25	56.99	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	3.587e-25	59.30	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-1	1.012e-24	55.43	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	1.087e-24	56.99	EGR (Early Growth factor Response factor) Homolog ...	[more]

BLAST of EGR-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sr	1.458e-25	53.76	gene:FBgn0003499 transcript:FBtr0330050	[more]
sr	1.910e-25	53.76	gene:FBgn0003499 transcript:FBtr0083542	[more]
sr	3.349e-25	53.76	gene:FBgn0003499 transcript:FBtr0301615	[more]
sr	5.083e-25	53.76	gene:FBgn0003499 transcript:FBtr0344633	[more]
sr	5.083e-25	53.76	gene:FBgn0003499 transcript:FBtr0083543	[more]

BLAST of EGR-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	4.797e-25	50.91	early growth response 1 [Source:NCBI gene;Acc:3049...	[more]
egr1	4.797e-25	50.91	early growth response 1 [Source:NCBI gene;Acc:3049...	[more]
egr3	1.692e-24	60.47	early growth response 3 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
egr4	2.493e-24	54.26	early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
egr2a	6.414e-24	45.45	early growth response 2a [Source:ZFIN;Acc:ZDB-GENE...	[more]

BLAST of EGR-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	1.160e-24	51.92	early growth response 1 [Source:NCBI gene;Acc:1000...	[more]
egr1	1.246e-24	51.92	early growth response 1 [Source:NCBI gene;Acc:1000...	[more]
usp31	1.711e-23	52.08	ubiquitin specific peptidase 31 [Source:Xenbase;Ac...	[more]
serpinb4	9.518e-23	60.00	serpin peptidase inhibitor, clade B (ovalbumin), m...	[more]
tbl1x	1.987e-22	58.54	transducin beta like 1 X-linked [Source:Xenbase;Ac...	[more]

BLAST of EGR-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Egr3	3.080e-24	57.65	early growth response 3 [Source:MGI Symbol;Acc:MGI...	[more]
Egr1	3.594e-24	51.96	early growth response 1 [Source:MGI Symbol;Acc:MGI...	[more]
Egr1	3.594e-24	51.96	early growth response 1 [Source:MGI Symbol;Acc:MGI...	[more]
Egr3	5.501e-24	57.65	early growth response 3 [Source:MGI Symbol;Acc:MGI...	[more]
Egr2	1.164e-23	45.04	early growth response 2 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of EGR-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P26632\|EGR1_DANRE	3.621e-24	50.91	Early growth response protein 1 OS=Danio rerio OX=...	[more]
sp\|A4II20\|EGR1_XENTR	6.146e-24	51.92	Early growth response protein 1 OS=Xenopus tropica...	[more]
sp\|Q6NTY6\|EGR1B_XENLA	1.028e-23	49.12	Early growth response protein 1-B OS=Xenopus laevi...	[more]
sp\|Q6GQH4\|EGR1A_XENLA	1.128e-23	49.12	Early growth response protein 1-A OS=Xenopus laevi...	[more]
sp\|O73693\|EGR1_TAEGU	1.816e-23	58.33	Early growth response protein 1 (Fragment) OS=Taen...	[more]

BLAST of EGR-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H9CXV3	0.000e+0	99.74	EGR-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
I1ZI72	1.454e-32	51.54	Early growth response-4 OS=Schmidtea mediterranea ...	[more]
A0A0B7BZD2	8.005e-27	43.57	Uncharacterized protein (Fragment) OS=Arion vulgar...	[more]
A0A3Q3E8P3	3.430e-25	46.72	Uncharacterized protein OS=Labrus bergylta OX=5672...	[more]
G1CSV5	1.114e-24	46.61	EGR-like protein 1 OS=Schmidtea mediterranea OX=79...	[more]

BLAST of EGR-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr3	1.553e-24	60.47	early growth response 3 [Source:NCBI gene;Acc:1030...	[more]
egr4	2.119e-24	42.45	early growth response protein 1-B [Source:NCBI gen...	[more]
egr4	2.782e-24	53.19	early growth response protein 1-B [Source:NCBI gen...	[more]
egr1	6.256e-24	55.43	early growth response 1 [Source:NCBI gene;Acc:1030...	[more]
egr2b	6.576e-23	58.54	early growth response 2 [Source:NCBI gene;Acc:1030...	[more]

BLAST of EGR-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr4	9.828e-24	55.81	early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
ENSPMAT00000005004.1	1.094e-17	35.04	pep scaffold:Pmarinus_7.0:GL484587:30140:35096:1 g...	[more]
wt1a	1.826e-16	48.84	WT1 transcription factor a [Source:ZFIN;Acc:ZDB-GE...	[more]
ENSPMAT00000000923.1	1.117e-15	37.50	pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 ...	[more]
ENSPMAT00000004792.1	1.465e-15	43.21	pep scaffold:Pmarinus_7.0:GL479046:11287:22931:1 g...	[more]

BLAST of EGR-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
AZF1	1.757e-14	33.33	Zinc-finger transcription factor; involved in diau...	[more]
MIG1	2.816e-13	39.58	Transcription factor involved in glucose repressio...	[more]
ZAP1	2.434e-12	39.76	Zinc-regulated transcription factor; binds to zinc...	[more]
MIG3	2.863e-11	49.18	Transcriptional regulator; partially nonfunctional...	[more]
MIG2	3.150e-11	47.54	Zinc finger transcriptional repressor; cooperates ...	[more]

BLAST of EGR-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49112	1.383e-23	58.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29702	2.648e-16	46.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38793	1.789e-15	39.29	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43177	2.330e-15	34.40	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31838	4.093e-15	46.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of EGR-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	8.336e-25	50.91	early growth response 1 [Source:NCBI gene;Acc:1002...	[more]
egr3	3.199e-24	57.65	early growth response 3 [Source:NCBI gene;Acc:1002...	[more]
ENSORLT00000000940.2	1.352e-23	43.94	early growth response protein 1 [Source:NCBI gene;...	[more]
egr2b	1.248e-22	58.54	early growth response 2 [Source:NCBI gene;Acc:1011...	[more]
ENSORLT00000034291.1	4.770e-22	56.47	early growth response protein 2b [Source:NCBI gene...	[more]

BLAST of EGR-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000034285.1	0.000e+0	98.71	SMESG000034285.1	[more]
SMESG000028801.1	4.374e-36	51.54	SMESG000028801.1	[more]
SMESG000028801.1	6.680e-36	51.54	SMESG000028801.1	[more]
SMESG000042500.1	6.978e-36	73.17	SMESG000042500.1	[more]
SMESG000000960.1	3.097e-28	46.61	SMESG000000960.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30012332
GenBank	AFD29624.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30012332 ID=SMED30012332|Name=EGR-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1460bp
GATCTAATAAAACCATGAAACCGGTTTTTGAATGAGACGCCACGCATTGT
CAGAGTCATTGGTCCGTGACGGTTATTTATTGGTTATAAAACTACCATAA
TTACACTTTTGGTGGTTGTATTTTCACAAAATGATTTTAGACGAGACTGC
TAATGATGATCCAACTGACTATGTTCATAATTCTAGTCATAACTCATCGT
TTGAGGTTCATTCGAAACAATTTGAAAATCTTTTAAGCATTCCAGCATAC
AATGATCACTGTGGATTCATTCAAAACATGGAATTTAATGGTGGAGGTTA
TCAGTATTCCAGCAATAATGGTAATTACAGTCTCCTTCAACAACTGAATT
CAGACCATTCAAATGATTTGCTTCAAATGTTACAAAATGACCCATTCATT
TCTACTGATTGCCGATTCATTACCGATTCGCAGTCGCAATATTTTCATCC
CTACCAGCAATACATGTGTCGGATTGCCAACAATAATTTCCATAACGTAA
ATAATTACGCCATCTATGACAATTCAAAATTGAAGCCCATTCCTCTTGAC
AGTTCTCAAATTTCCAATCAAACAAACATAAAACTTGAACCATTACACGA
TCCGATCAGTAGAATTTCGAGAGAGGAAAAATCAAAATCTGGCAAATCCA
ATCAACTGCCACCCGACAAATCTTTTACCTGTTCGAATTGTCCGAGTCGA
TTTACAAGAAAAGACGAATTGAGACGACACGAAAAAATTCATACCGGTAT
TAAAACTCTCTGTTGCCCATATTGTGATAAAACTTTCATCCGGTCGGATC
ATCGGCGAACTCATATTCGAACACATACCGGCGAGAAGCCTTATTCCTGT
GAGATTTGTTGCAAATGTTTCGCTCGGTCTGATGAGCGGACACGGCACAC
AAGAATTCACAGTAAAGATCCAGTCAGAAAACGAAAGAAACCAAATGCAA
ATAATAATACTAGCAATAATGATTATACCAAAAGTGCAATTATTGATTTG
GATTCTTTGAAGTCCAATCTTCCTTTAGTGCAAAACAAAGAGCCTTTTGT
TGAGTCCTACTATCAAATTCATCCCGAAATCTTTATACGTGAATCTCTCA
AGGACCCCAGCAGATACAATCCGGCCTTCGATAATAACTCATTAATCCGG
AATAAAGACGCTACCACCAAATCAAAGGCCTTCATAAAAATCGAGCCACA
TATTAATGATGCAATTTCAGACATGACTGCAAATATTGCCAAATATTACC
ATTTCAGTGATAAAAGTAGCTCCCCATCAACGGAAATATCAATTGATTAA
TGTTATTTTTAATAAATAATTTTTTATTAATATAATATTTAATTTGATTA
TATTTTTTGGTTCTATTAGTGACAATGAAATATAAACACCGGCTGCCAGT
AATAGTTTCTCTACTATTTTTAATGTTAAATCCGCGTGTGAAAATATTAT
TTTTGGAAGC

protein sequence of SMED30012332-orf-1

>SMED30012332-orf-1 ID=SMED30012332-orf-1|Name=SMED30012332-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=390bp
MILDETANDDPTDYVHNSSHNSSFEVHSKQFENLLSIPAYNDHCGFIQNM
EFNGGGYQYSSNNGNYSLLQQLNSDHSNDLLQMLQNDPFISTDCRFITDS
QSQYFHPYQQYMCRIANNNFHNVNNYAIYDNSKLKPIPLDSSQISNQTNI
KLEPLHDPISRISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRH
EKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARS
DERTRHTRIHSKDPVRKRKKPNANNNTSNNDYTKSAIIDLDSLKSNLPLV
QNKEPFVESYYQIHPEIFIRESLKDPSRYNPAFDNNSLIRNKDATTKSKA
FIKIEPHINDAISDMTANIAKYYHFSDKSSSPSTEISID*

Aliases

The feature 'EGR-1' has the following synonyms


Synonym
EGR-1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000028	Category 2 cell
PLANA:0000035	Category 3 cell
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002075	pigment cell
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036236	Znf_C2H2_sf
IPR015880	Znf_C2H2-like
IPR013087	Znf_C2H2_type
IPR007087	Znf_C2H2

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013087	Zinc finger C2H2-type	SMART	SM00355	c2h2final6	coord: 210..232 e-value: 0.074 score: 22.2 coord: 182..204 e-value: 0.0021 score: 27.3 coord: 238..260 e-value: 0.67 score: 19.0
IPR013087	Zinc finger C2H2-type	PFAM	PF00096	zf-C2H2	coord: 182..204 e-value: 0.0012 score: 19.2 coord: 212..232 e-value: 5.5E-4 score: 20.2
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 211..232
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 240..260
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 184..204
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 238..265 score: 11.115
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 182..209 score: 13.568
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 210..237 score: 14.108
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 210..237 e-value: 2.8E-11 score: 45.1
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 238..263 e-value: 9.8E-10 score: 40.3
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 162..206 e-value: 4.6E-8 score: 34.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 255..281
None	No IPR available	PANTHER	PTHR24384:SF205	ZINC FINGER PROTEIN 977	coord: 179..263
None	No IPR available	PANTHER	PTHR24384	FAMILY NOT NAMED	coord: 178..262
None	No IPR available	PANTHER	PTHR24384	FAMILY NOT NAMED	coord: 179..263
None	No IPR available	PANTHER	PTHR24384:SF205	ZINC FINGER PROTEIN 977	coord: 178..262
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 208..260
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 179..219