DDHD domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012287 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]) HSP 1 Score: 359.762 bits (922), Expect = 4.107e-111 Identity = 243/732 (33.20%), Postives = 360/732 (49.18%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSN--------------------------------LESST------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRR------NPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMN--------------NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
L PEE RWFYK +K +K F GYDSLR+E FR L G +S+T E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + NP K + + + IS S V+ P H+ + +A SI+ A + L +S R + + KD + P +P + L L R+D+ L E S Y S +TSHT+YW L++A FL+ M
Sbjct: 163 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAK-EPTSVSENEGISTIPSPVTS----------PVLSRRHYGESITNIGKA-SILGAASIGKGLGGML--FSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFM 856
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]) HSP 1 Score: 357.066 bits (915), Expect = 5.763e-110 Identity = 244/739 (33.02%), Postives = 360/739 (48.71%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSN--------------------------------LESST------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK---------NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRR------NPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMN--------------NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
L PEE RWFYK +K +K F GYDSLR+E FR L G +S+T E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ N +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + NP K + + + IS S V+ P H+ + +A SI+ A + L +S R + + KD + P +P + L L R+D+ L E S Y S +TSHT+YW L++A FL+ M
Sbjct: 163 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDGSGINYSAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAK-EPTSVSENEGISTIPSPVTS----------PVLSRRHYGESITNIGKA-SILGAASIGKGLGGML--FSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFM 863
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]) HSP 1 Score: 346.665 bits (888), Expect = 6.072e-106 Identity = 203/546 (37.18%), Postives = 295/546 (54.03%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSN--------------------------------LESST------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
L PEE RWFYK +K +K F GYDSLR+E FR L G +S+T E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 163 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQI 684
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]) HSP 1 Score: 332.413 bits (851), Expect = 7.877e-103 Identity = 217/670 (32.39%), Postives = 332/670 (49.55%), Query Frame = 2
Query: 281 EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQY-------------------------------------SCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRR------NPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMN--------------NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q S + + +K+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + NP K + + + IS S V+ P H+ + +A SI+ A + L +S R + + KD + P +P + L L R+D+ L E S Y S +TSHT+YW L++A FL+ M
Sbjct: 24 EPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDVVYHLPPFSLPSLFKWRRYKESTDATGLKRKHSQAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAK-EPTSVSENEGISTIPSPVTS----------PVLSRRHYGESITNIGKA-SILGAASIGKGLGGML--FSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFM 659
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]) HSP 1 Score: 323.939 bits (829), Expect = 1.237e-98 Identity = 176/442 (39.82%), Postives = 261/442 (59.05%), Query Frame = 2
Query: 305 LFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 134 LYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQI 555
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1]) HSP 1 Score: 225.328 bits (573), Expect = 5.660e-63 Identity = 166/544 (30.51%), Postives = 253/544 (46.51%), Query Frame = 2
Query: 113 KIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFR----------------------------ELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIES---QFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQR-LAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFD-YQFKSSDELLLKN-----RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHV-CQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSED 1627
K+ L E RWF+ ++ + ++ F+G DS+ LE K+R E I G +E ++V + ++ + PIYW D D+ +I RG+WF D ++PL L+D IE Q N + + + + S N+ V+ + Y I W ++ + L+ + R K + + RGY+++ +D ++ISHL VVHGIGQ+ I + +++ S ++K Y K R FLP+EWR+ L LD G+ D+IT +R N+T MD++YY S L++ EI GV S+ NR Y +F + NP F G VS+ HSLGSVICYD++ + + + FD Y KS DE L ++ + + E + D + K + +E+Q F V F +GSPL VFL +RG + D+L K +R+FNI+H DPVAYRLEP EY I P IKL ++ D
Sbjct: 55 KVTELKCSEVRWFF---QEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKD--DSKEIRRGSWFSPD-YQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSVIDISLHQKGNAILRYLWAKST-------PLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQY-------SPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQLEF--------------KVKYLFAVGSPLGVFLTMRG------GESTDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRP--IKLFSNTD 550
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1]) HSP 1 Score: 225.328 bits (573), Expect = 8.908e-63 Identity = 166/544 (30.51%), Postives = 253/544 (46.51%), Query Frame = 2
Query: 113 KIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFR----------------------------ELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIES---QFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQR-LAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFD-YQFKSSDELLLKN-----RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHV-CQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSED 1627
K+ L E RWF+ ++ + ++ F+G DS+ LE K+R E I G +E ++V + ++ + PIYW D D+ +I RG+WF D ++PL L+D IE Q N + + + + S N+ V+ + Y I W ++ + L+ + R K + + RGY+++ +D ++ISHL VVHGIGQ+ I + +++ S ++K Y K R FLP+EWR+ L LD G+ D+IT +R N+T MD++YY S L++ EI GV S+ NR Y +F + NP F G VS+ HSLGSVICYD++ + + + FD Y KS DE L ++ + + E + D + K + +E+Q F V F +GSPL VFL +RG + D+L K +R+FNI+H DPVAYRLEP EY I P IKL ++ D
Sbjct: 81 KVTELKCSEVRWFF---QEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKD--DSKEIRRGSWFSPD-YQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSVIDISLHQKGNAILRYLWAKST-------PLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQY-------SPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQLEF--------------KVKYLFAVGSPLGVFLTMRG------GESTDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRP--IKLFSNTD 576
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1]) HSP 1 Score: 224.942 bits (572), Expect = 1.005e-62 Identity = 166/544 (30.51%), Postives = 253/544 (46.51%), Query Frame = 2
Query: 113 KIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFR----------------------------ELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIES---QFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQR-LAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFD-YQFKSSDELLLKN-----RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHV-CQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSED 1627
K+ L E RWF+ ++ + ++ F+G DS+ LE K+R E I G +E ++V + ++ + PIYW D D+ +I RG+WF D ++PL L+D IE Q N + + + + S N+ V+ + Y I W ++ + L+ + R K + + RGY+++ +D ++ISHL VVHGIGQ+ I + +++ S ++K Y K R FLP+EWR+ L LD G+ D+IT +R N+T MD++YY S L++ EI GV S+ NR Y +F + NP F G VS+ HSLGSVICYD++ + + + FD Y KS DE L ++ + + E + D + K + +E+Q F V F +GSPL VFL +RG + D+L K +R+FNI+H DPVAYRLEP EY I P IKL ++ D
Sbjct: 79 KVTELKCSEVRWFF---QEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKD--DSKEIRRGSWFSPD-YQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSVIDISLHQKGNAILRYLWAKST-------PLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQY-------SPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQLEF--------------KVKYLFAVGSPLGVFLTMRG------GESTDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRP--IKLFSNTD 574
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1]) HSP 1 Score: 226.098 bits (575), Expect = 1.076e-62 Identity = 166/544 (30.51%), Postives = 253/544 (46.51%), Query Frame = 2
Query: 113 KIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFR----------------------------ELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIES---QFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQR-LAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFD-YQFKSSDELLLKN-----RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHV-CQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSED 1627
K+ L E RWF+ ++ + ++ F+G DS+ LE K+R E I G +E ++V + ++ + PIYW D D+ +I RG+WF D ++PL L+D IE Q N + + + + S N+ V+ + Y I W ++ + L+ + R K + + RGY+++ +D ++ISHL VVHGIGQ+ I + +++ S ++K Y K R FLP+EWR+ L LD G+ D+IT +R N+T MD++YY S L++ EI GV S+ NR Y +F + NP F G VS+ HSLGSVICYD++ + + + FD Y KS DE L ++ + + E + D + K + +E+Q F V F +GSPL VFL +RG + D+L K +R+FNI+H DPVAYRLEP EY I P IKL ++ D
Sbjct: 142 KVTELKCSEVRWFF---QEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKD--DSKEIRRGSWFSPD-YQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSVIDISLHQKGNAILRYLWAKST-------PLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQY-------SPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQLEF--------------KVKYLFAVGSPLGVFLTMRG------GESTDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRP--IKLFSNTD 637
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1]) HSP 1 Score: 224.172 bits (570), Expect = 1.945e-62 Identity = 166/544 (30.51%), Postives = 253/544 (46.51%), Query Frame = 2
Query: 113 KIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFR----------------------------ELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIES---QFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQR-LAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFD-YQFKSSDELLLKN-----RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHV-CQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSED 1627
K+ L E RWF+ ++ + ++ F+G DS+ LE K+R E I G +E ++V + ++ + PIYW D D+ +I RG+WF D ++PL L+D IE Q N + + + + S N+ V+ + Y I W ++ + L+ + R K + + RGY+++ +D ++ISHL VVHGIGQ+ I + +++ S ++K Y K R FLP+EWR+ L LD G+ D+IT +R N+T MD++YY S L++ EI GV S+ NR Y +F + NP F G VS+ HSLGSVICYD++ + + + FD Y KS DE L ++ + + E + D + K + +E+Q F V F +GSPL VFL +RG + D+L K +R+FNI+H DPVAYRLEP EY I P IKL ++ D
Sbjct: 67 KVTELKCSEVRWFF---QEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQYKVNKDNSKIDPIYWKD--DSKEIRRGSWFSPD-YQPLEMPLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVLAELHVDGYDIRWSSVIDISLHQKGNAILRYLWAKST-------PLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQY-------SPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQLEF--------------KVKYLFAVGSPLGVFLTMRG------GESTDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRP--IKLFSNTD 562
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0339673) HSP 1 Score: 122.865 bits (307), Expect = 4.161e-28 Identity = 131/512 (25.59%), Postives = 221/512 (43.16%), Query Frame = 2
Query: 131 PEETRWFYK-SVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWF---IADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDD------KQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKF------RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
P WFYK SV+ K I+ FS YDS LET NL+ ST I V+ ++ ++ +R P+YW ++ R +WF + + P E+ A +E+++ + + + ++K++ A N ++ + + + + + Q +R K LDD + + HL F+VHGIG + R ++ ++ + ++ H + R+E LPI W +L+ + ID SIT + LR N+T++D+L+Y+S Y +I + V N +Y + R+P F G VS+ HSLGS+I +D+ L K S+E +N+ L S+ + + + S + P T ++ K FF LGSP+ +F+ +RG++ K +D + LP C +NI+H DPVAYR+E L+ + I PV I
Sbjct: 1375 PVVAHWFYKRSVDT--KFIWTPFSHYDSALLETSL----------NLDDSTLIIPVEGGRYDVNIKERTKTPVYW--EGKAIEVRRCSWFYKGVDSKYVPYTEDTAALLEAEYKRS----------AETGEWHQKIMLA-----------NGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRVVKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKM-RSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFN---GGVSLAGHSLGSLILFDL--------------LCHQEPLKESEE---ENKNPDQLPQKQSSQKVQLPTSDPLPKQVSYAMGPEGTGQPVITYTQLIFHPKK----FFALGSPIGMFVTIRGID-KLGLDFH--LP--TCPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLI 1821
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0344863) HSP 1 Score: 101.679 bits (252), Expect = 6.388e-22 Identity = 91/359 (25.35%), Postives = 159/359 (44.29%), Query Frame = 2
Query: 131 PEETRWFYK-SVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWF---IADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDD------KQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKF------RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
P WFYK SV+ K I+ FS YDS LET NL+ ST I V+ ++ ++ +R P+YW ++ R +WF + + P E+ A +E+++ + + + ++K++ A N ++ + + + + + Q +R K LDD + + HL F+VHGIG + R ++ ++ + ++ H + R+E LPI W +L+ + ID SIT + LR N+T++D+L+Y+S Y +I + V N +Y + R+P F G VS+ HSLGS+I +D++
Sbjct: 22 PVVAHWFYKRSVDT--KFIWTPFSHYDSALLETSL----------NLDDSTLIIPVEGGRYDVNIKERTKTPVYW--EGKAIEVRRCSWFYKGVDSKYVPYTEDTAALLEAEYKRS----------AETGEWHQKIMLA-----------NGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRVVKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKM-RSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEF---NGGVSLAGHSLGSLILFDLL 341
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0302595) HSP 1 Score: 101.679 bits (252), Expect = 6.388e-22 Identity = 91/359 (25.35%), Postives = 159/359 (44.29%), Query Frame = 2
Query: 131 PEETRWFYK-SVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWF---IADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDD------KQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKF------RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
P WFYK SV+ K I+ FS YDS LET NL+ ST I V+ ++ ++ +R P+YW ++ R +WF + + P E+ A +E+++ + + + ++K++ A N ++ + + + + + Q +R K LDD + + HL F+VHGIG + R ++ ++ + ++ H + R+E LPI W +L+ + ID SIT + LR N+T++D+L+Y+S Y +I + V N +Y + R+P F G VS+ HSLGS+I +D++
Sbjct: 22 PVVAHWFYKRSVDT--KFIWTPFSHYDSALLETSL----------NLDDSTLIIPVEGGRYDVNIKERTKTPVYW--EGKAIEVRRCSWFYKGVDSKYVPYTEDTAALLEAEYKRS----------AETGEWHQKIMLA-----------NGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRVVKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKM-RSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEF---NGGVSLAGHSLGSLILFDLL 341
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0079641) HSP 1 Score: 102.064 bits (253), Expect = 1.136e-21 Identity = 91/359 (25.35%), Postives = 159/359 (44.29%), Query Frame = 2
Query: 131 PEETRWFYK-SVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWF---IADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDD------KQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKF------RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
P WFYK SV+ K I+ FS YDS LET NL+ ST I V+ ++ ++ +R P+YW ++ R +WF + + P E+ A +E+++ + + + ++K++ A N ++ + + + + + Q +R K LDD + + HL F+VHGIG + R ++ ++ + ++ H + R+E LPI W +L+ + ID SIT + LR N+T++D+L+Y+S Y +I + V N +Y + R+P F G VS+ HSLGS+I +D++
Sbjct: 1375 PVVAHWFYKRSVDT--KFIWTPFSHYDSALLETSL----------NLDDSTLIIPVEGGRYDVNIKERTKTPVYW--EGKAIEVRRCSWFYKGVDSKYVPYTEDTAALLEAEYKRS----------AETGEWHQKIMLA-----------NGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRVVKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKM-RSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFN---GGVSLAGHSLGSLILFDLL 1694
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: rdgB (gene:FBgn0003218 transcript:FBtr0331717) HSP 1 Score: 62.3882 bits (150), Expect = 1.650e-9 Identity = 29/70 (41.43%), Postives = 43/70 (61.43%), Query Frame = 2
Query: 1397 VDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
V +FFM GSPL V L R L+ D LP+ C +++N++H +DP+A RLEPLL + + PV++
Sbjct: 747 VCDFFMFGSPLSVVLAARKLH-----DAKAALPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNV 811
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16]) HSP 1 Score: 355.525 bits (911), Expect = 6.202e-111 Identity = 228/704 (32.39%), Postives = 361/704 (51.28%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL------------------SIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS------CLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSL----SFDYQFKSS------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKG-------KDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
L PEE RWFYK +K +K F G+DSL +E +R + + + ++++ E + V+ L+E DV + C P+YW + + + RG WF T+ P+ E+ ++ IE + + F Q L V +K+ IH+++ S ++WY++ E YLY S R +KL S S G ++ RGY E+ SLDDK + +H+ FV+HGIGQ++ I + L+++ + + +K+Y+ ++ +EFLP+EWR+ L LDG ++SITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE GGKVSII+HSLG VI +DI+ W L + D Q+ S +E+ L ++L +L++ + LK K +FP+ FK V+NFF +G PL VFL LRG+ P N Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y +I PV I N NP ++++ +S ++ S E+ + P H+ + +A SI+ A L + F + +L + G + T + P ++ + + + + R+D+ L E S Y S +TSHT+YW ++A FL+
Sbjct: 85 LGPEEVRWFYKE----DKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYW-NQQERIPVMRGQWFTDATWAPVEEDESELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKD--AIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYSEQ--TEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEERHLLEEVQLTRQRLHELRDQLHG-----------------LKESKPASFPTLKFK----------VENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWC-------NTINPTPYDEIR---PTYLSTSKDTASDMENGSSPSTSPVLARRHYGESITNLGKA-SILGAAS-LGKGIGGILFSHFSRSPSLPSAVDSGMGDSEDSQSTFTFSAIPPSSSSSLFDATVEMEHRIDFELREGMVESRYWSAVTSHTAYWTSHDVALFLL 740
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16]) HSP 1 Score: 355.525 bits (911), Expect = 1.965e-110 Identity = 228/704 (32.39%), Postives = 361/704 (51.28%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL------------------SIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS------CLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSL----SFDYQFKSS------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKG-------KDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
L PEE RWFYK +K +K F G+DSL +E +R + + + ++++ E + V+ L+E DV + C P+YW + + + RG WF T+ P+ E+ ++ IE + + F Q L V +K+ IH+++ S ++WY++ E YLY S R +KL S S G ++ RGY E+ SLDDK + +H+ FV+HGIGQ++ I + L+++ + + +K+Y+ ++ +EFLP+EWR+ L LDG ++SITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE GGKVSII+HSLG VI +DI+ W L + D Q+ S +E+ L ++L +L++ + LK K +FP+ FK V+NFF +G PL VFL LRG+ P N Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y +I PV I N NP ++++ +S ++ S E+ + P H+ + +A SI+ A L + F + +L + G + T + P ++ + + + + R+D+ L E S Y S +TSHT+YW ++A FL+
Sbjct: 120 LGPEEVRWFYKE----DKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYW-NQQERIPVMRGQWFTDATWAPVEEDESELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKD--AIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYSEQ--TEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEERHLLEEVQLTRQRLHELRDQLHG-----------------LKESKPASFPTLKFK----------VENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWC-------NTINPTPYDEIR---PTYLSTSKDTASDMENGSSPSTSPVLARRHYGESITNLGKA-SILGAA-SLGKGIGGILFSHFSRSPSLPSAVDSGMGDSEDSQSTFTFSAIPPSSSSSLFDATVEMEHRIDFELREGMVESRYWSAVTSHTAYWTSHDVALFLL 775
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16]) HSP 1 Score: 345.125 bits (884), Expect = 2.562e-106 Identity = 228/734 (31.06%), Postives = 361/734 (49.18%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL------------------SIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQ---------------------------------YSCLDSNVSQKNRK---VIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSL----SFDYQFKSS------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKG-------KDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
L PEE RWFYK +K +K F G+DSL +E +R + + + ++++ E + V+ L+E DV + C P+YW + + + RG WF T+ P+ E+ ++ IE + + F Q +S + RK IH+++ S ++WY++ E YLY S R +KL S S G ++ RGY E+ SLDDK + +H+ FV+HGIGQ++ I + L+++ + + +K+Y+ ++ +EFLP+EWR+ L LDG ++SITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE GGKVSII+HSLG VI +DI+ W L + D Q+ S +E+ L ++L +L++ + LK K +FP+ FK V+NFF +G PL VFL LRG+ P N Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y +I PV I N NP ++++ +S ++ S E+ + P H+ + +A SI+ A L + F + +L + G + T + P ++ + + + + R+D+ L E S Y S +TSHT+YW ++A FL+
Sbjct: 120 LGPEEVRWFYKE----DKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYW-NQQERIPVMRGQWFTDATWAPVEEDESELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKDVLSHFPPFYLPFLFKWSGYQTGAKSHKRKRCQAIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYSEQ--TEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEERHLLEEVQLTRQRLHELRDQLHG-----------------LKESKPASFPTLKFK----------VENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWC-------NTINPTPYDEIR---PTYLSTSKDTASDMENGSSPSTSPVLARRHYGESITNLGKA-SILGAA-SLGKGIGGILFSHFSRSPSLPSAVDSGMGDSEDSQSTFTFSAIPPSSSSSLFDATVEMEHRIDFELREGMVESRYWSAVTSHTAYWTSHDVALFLL 807
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16]) HSP 1 Score: 345.125 bits (884), Expect = 2.562e-106 Identity = 228/734 (31.06%), Postives = 361/734 (49.18%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL------------------SIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQ---------------------------------YSCLDSNVSQKNRK---VIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSL----SFDYQFKSS------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKG-------KDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
L PEE RWFYK +K +K F G+DSL +E +R + + + ++++ E + V+ L+E DV + C P+YW + + + RG WF T+ P+ E+ ++ IE + + F Q +S + RK IH+++ S ++WY++ E YLY S R +KL S S G ++ RGY E+ SLDDK + +H+ FV+HGIGQ++ I + L+++ + + +K+Y+ ++ +EFLP+EWR+ L LDG ++SITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE GGKVSII+HSLG VI +DI+ W L + D Q+ S +E+ L ++L +L++ + LK K +FP+ FK V+NFF +G PL VFL LRG+ P N Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y +I PV I N NP ++++ +S ++ S E+ + P H+ + +A SI+ A L + F + +L + G + T + P ++ + + + + R+D+ L E S Y S +TSHT+YW ++A FL+
Sbjct: 120 LGPEEVRWFYKE----DKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYW-NQQERIPVMRGQWFTDATWAPVEEDESELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKDVLSHFPPFYLPFLFKWSGYQTGAKSHKRKRCQAIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYSEQ--TEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEERHLLEEVQLTRQRLHELRDQLHG-----------------LKESKPASFPTLKFK----------VENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWC-------NTINPTPYDEIR---PTYLSTSKDTASDMENGSSPSTSPVLARRHYGESITNLGKA-SILGAA-SLGKGIGGILFSHFSRSPSLPSAVDSGMGDSEDSQSTFTFSAIPPSSSSSLFDATVEMEHRIDFELREGMVESRYWSAVTSHTAYWTSHDVALFLL 807
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1b (DDHD domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-040724-18]) HSP 1 Score: 326.635 bits (836), Expect = 4.723e-99 Identity = 232/759 (30.57%), Postives = 356/759 (46.90%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELS------------------IFKGKSNLESST-----------------------------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQY------SCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLS--FDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPRE------------------------------------MNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
L PEE RWFYK +K +K F G+DSL++E +R+ +F+ S E + + V+ L+E D+ + C P+YW + D+ + RG WF T+ PL E +D IE + + F Q + + V K+ IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+D + +H+ FVVHGIGQ++ G I R ++ + + + +K+++ + +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+Y +FC RNP F K GKVSI++HSLG VI +DI+ W +P ++ + + + LL+ +LT L+ D+ D ++ T S+ +P+ FK V+NFF +GSPL VFL LRG+ P + Q+ ILP +CQR+FNI+H +DPVAYRLEPL++K Y I PV I N +P P D P + S + VS E P H+S + +A SIM A + + RF+ + G + +T++ G + M+ +L L +R+D+ L E S Y S +TSHT+YW ++A FL+
Sbjct: 128 LGPEEVRWFYKE----DKRTWKPFVGHDSLKIELAYRKYCELNPEEVKRRDATEEAEDLFESSSGCEEPAVRRQSAAVAAQPVPDSADAGCSADDSVFRSDSVNVDAVCVRGGLYEVDIKGKSCYPVYW-NQQDHIPVMRGQWFTDGTWLPLEEEDSDLIELEHLACFRGQQMKDTFDTEAVATTVDSKD--AIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEAALEDTPPETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEEKHFSDRINE--HVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDEITRGLTKELNRLYMLFCERNPEFAEK-GKVSIVSHSLGCVITFDIMTGW-DPVRFVHEDVPDVMEADVSRQERQLLEELRLTYLRIR------DLEDRLQNFQTSSS-----RPSPALKFK----------VENFFCMGSPLAVFLALRGVRPGSGGTQDHILPTSICQRLFNIFHPTDPVAYRLEPLILKHYSNITPVQIHWY-------NTTSP-TPYDQIRPTLLNPSKENASVSDTESLPSPCTSPPQPRRHYSESITNLGKA-SIMGAA-SIGKGIGGI----LFSRFSRSSGQVGGVEEETSDSEGGTCEKGDENRSVDLDDKPDEKTEEKIEEKTGDTSMSQSASTIMDYSSLELEKRIDFELREGLVESRYWSAVTSHTAYWCSHDVALFLL 840
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824]) HSP 1 Score: 367.081 bits (941), Expect = 1.623e-114 Identity = 244/698 (34.96%), Postives = 354/698 (50.72%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL-----SIFKGKSNLESS-----------TEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKS---SDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKD----------LKTNNIPPGNNPREMN---NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
L PEE RWFYK +K +K F GYDSLR+E +R+L + K +S E E + V+S L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + F Q LD+ +++ ++ H++K S ++W+N+ E YLY S R +KL S S G ++ RGY E+ S +DK DI+H+ FVVHGIGQ++ G I + ++ + + + +K++ PH + +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ E+ G+Q E NR+Y++FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP D + +E LL+ LT + K + R N P+ FK V+NFF +GSPL VFL LRG+ P N Q+ ILPK +C R+FNI+H +DPVAYRLEPL++K Y I PV I N NP ++K P S + +S E + P H+ + +A SI+ A + + F + KD L ++ P M+ + L L R+D+ L E S Y S +TSHT+YW +++A FL+
Sbjct: 141 LSPEEVRWFYKE----DKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYW-NQTDKIPVMRGQWFIDGTWQPLDEEESNLIEQDHLTCFRGQQMQDNLDTEITKPVDDKDASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHF-PHFVTD-HVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGW-NPGQLYEQQEDDDADVQGISYEEEHLLRELYLTKQR-------------LKELEVRLHEVRASLSNAPALKFK----------VENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQI-------HSSNTTNPLPYKNIK-PCFINPSKDTTSMSDTESIPSPSTSPVLPRRHYGESITNIGKA-SILGAAS-IGKGLGGMLFSRFARSSATGTPGCDSKDSAEGEDKKSVLSQSSTGSQALPHSMSGLLDSTLELEHRIDFELREGLVESRYWSAMTSHTAYWSSMDVALFLL 797
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824]) HSP 1 Score: 314.309 bits (804), Expect = 6.377e-97 Identity = 207/601 (34.44%), Postives = 304/601 (50.58%), Query Frame = 2
Query: 383 RGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSD--------ELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKD----------LKTNNIPPGNNPREMN---NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
RG WFI T++PL E ++ IE + F Q LD+ +++ ++ H++K S ++W+N+ E YLY S R +KL S S G ++ RGY E+ S +DK DI+H+ FVVHGIGQ++ G I + ++ + + + +K++ PH + +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ E+ G+Q E NR+Y++FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP D + EL L ++L +L+ + R N P+ FK V+NFF +GSPL VFL LRG+ P N Q+ ILPK +C R+FNI+H +DPVAYRLEPL++K Y I PV I N NP ++K P S + +S E + P H+ + +A SI+ A + + F + KD L ++ P M+ + L L R+D+ L E S Y S +TSHT+YW +++A FL+
Sbjct: 2 RGQWFIDGTWQPLDEEESNLIEQDHLTCFRGQQMQDNLDTEITKPVDDKDASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHF-PHFVTD-HVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGW-NPGQLYEQQEDDDADVQGISYEEEHLLRELYLTKQRLKELEVRLHEV------------------RASLSNAPALKFK----------VENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQI-------HSSNTTNPLPYKNIK-PCFINPSKDTTSMSDTESIPSPSTSPVLPRRHYGESITNIGKA-SILGAA-SIGKGLGGMLFSRFARSSATGTPGCDSKDSAEGEDKKSVLSQSSTGSQALPHSMSGLLDSTLELEHRIDFELREGLVESRYWSAMTSHTAYWSSMDVALFLL 561
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824]) HSP 1 Score: 280.026 bits (715), Expect = 2.233e-83 Identity = 155/384 (40.36%), Postives = 227/384 (59.11%), Query Frame = 2
Query: 92 NPSI-GENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL-----SIFKGKSNLESS-----------TEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPN 1168
+P I GE+ E PEE RWFYK +K +K F GYDSLR+E +R+L + K +S E E + V+S L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + F Q LD+ +++ ++ H++K S ++W+N+ E YLY S R +KL S S G ++ RGY E+ S +DK DI+H+ FVVHGIGQ++ G I + ++ + + + +K++ PH + +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ E+ G+Q E NR+Y++FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP
Sbjct: 11 SPEINGESVWEPGGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYW-NQTDKIPVMRGQWFIDGTWQPLDEEESNLIEQDHLTCFRGQQMQDNLDTEITKPVDDKDASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHF-PHFVTD-HVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGW-NPG 386 HSP 2 Score: 112.849 bits (281), Expect = 3.330e-25 Identity = 84/262 (32.06%), Postives = 123/262 (46.95%), Query Frame = 2
Query: 1355 SNFKTGNLW--KEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKD----------LKTNNIPPGNNPREMN---NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
+ + G L+ +E +V+NFF +GSPL VFL LRG+ P N Q+ ILPK +C R+FNI+H +DPVAYRLEPL++K Y I PV I N NP ++K P S + +S E + P H+ + +A SI+ A + + F + KD L ++ P M+ + L L R+D+ L E S Y S +TSHT+YW +++A FL+
Sbjct: 381 TGWNPGQLYEQQEDDDVENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQI-------HSSNTTNPLPYKNIK-PCFINPSKDTTSMSDTESIPSPSTSPVLPRRHYGESITNIGKA-SILGAA-SIGKGLGGMLFSRFARSSATGTPGCDSKDSAEGEDKKSVLSQSSTGSQALPHSMSGLLDSTLELEHRIDFELREGLVESRYWSAMTSHTAYWSSMDVALFLL 632
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824]) HSP 1 Score: 275.018 bits (702), Expect = 2.044e-80 Identity = 151/379 (39.84%), Postives = 221/379 (58.31%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL-----SIFKGKSNLESS-----------TEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK---------NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPN 1168
L PEE RWFYK +K +K F GYDSLR+E +R+L + K +S E E + V+S L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + F Q LD+ +++ ++ H++K S ++W+N+ E YLY S R +KL S S G ++ RGY E+ S +DK DI+H+ FVVHGIGQ++ G I + ++ + + + +K++ PH + +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ E+ G+Q E NR+Y++FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP
Sbjct: 141 LSPEEVRWFYKE----DKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYW-NQTDKIPVMRGQWFIDGTWQPLDEEESNLIEQDHLTCFRGQQMQDNLDTEITKPVDDKDGEINSQASSHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHF-PHFVTD-HVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGW-NPG 511 HSP 2 Score: 112.464 bits (280), Expect = 6.472e-25 Identity = 84/262 (32.06%), Postives = 123/262 (46.95%), Query Frame = 2
Query: 1355 SNFKTGNLW--KEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKD----------LKTNNIPPGNNPREMN---NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLI 2095
+ + G L+ +E +V+NFF +GSPL VFL LRG+ P N Q+ ILPK +C R+FNI+H +DPVAYRLEPL++K Y I PV I N NP ++K P S + +S E + P H+ + +A SI+ A + + F + KD L ++ P M+ + L L R+D+ L E S Y S +TSHT+YW +++A FL+
Sbjct: 506 TGWNPGQLYEQQEDDDVENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQI-------HSSNTTNPLPYKNIK-PCFINPSKDTTSMSDTESIPSPSTSPVLPRRHYGESITNIGKA-SILGAA-SIGKGLGGMLFSRFARSSATGTPGCDSKDSAEGEDKKSVLSQSSTGSQALPHSMSGLLDSTLELEHRIDFELREGLVESRYWSAMTSHTAYWSSMDVALFLL 757
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824]) HSP 1 Score: 264.618 bits (675), Expect = 8.852e-77 Identity = 152/406 (37.44%), Postives = 221/406 (54.43%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL-----SIFKGKSNLESS-----------TEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQ------------------------------------KNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPN 1168
L PEE RWFYK +K +K F GYDSLR+E +R+L + K +S E E + V+S L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + F Q LD+ +++ K + H++K S ++W+N+ E YLY S R +KL S S G ++ RGY E+ S +DK DI+H+ FVVHGIGQ++ G I + ++ + + + +K++ PH + +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ E+ G+Q E NR+Y++FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP
Sbjct: 141 LSPEEVRWFYKE----DKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYW-NQTDKIPVMRGQWFIDGTWQPLDEEESNLIEQDHLTCFRGQQMQDNLDTEITKPVDDKDVISHLPPFSLPFLFKWSGYKENTKAPCAKRKRCEASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHF-PHFVTD-HVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGW-NPG 538 HSP 2 Score: 101.293 bits (251), Expect = 2.085e-21 Identity = 46/86 (53.49%), Postives = 61/86 (70.93%), Query Frame = 2
Query: 1355 SNFKTGNLW--KEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
+ + G L+ +E +V+NFF +GSPL VFL LRG+ P N Q+ ILPK +C R+FNI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 533 TGWNPGQLYEQQEDDDVENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQI 618
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302]) HSP 1 Score: 366.696 bits (940), Expect = 5.291e-114 Identity = 248/740 (33.51%), Postives = 360/740 (48.65%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL---------------------SIFKGKSNLESST--------------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSS-----------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI------GNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMN--------------NENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
L PEE RWFYK +K +K F GYDSLR+E FR L S G+ + E S E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S SH+ FVVHGIGQ++ G I + ++++ + + +K+++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP L + + DEL + R+L ++++ + + I S T + FK V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + N NP K + D + I+A S V+ P H+ + +A SI+ A + L +S R + KD ++ P +P + L L R+D+ L E S Y S +TSHT+YW L++A FL+ M
Sbjct: 150 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGAQARAAGRDGDRVCGPSSSFGEEDEEDSACGFCPRAAGPEPEMEELVTIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSCFRGQQMQENFDIEVSKSLDGKDAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGW-NPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSI-----SQTPAL-----------KFK----------VENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAK-EPTSVSDSENIAAIPSPVTS----------PVLSRRHYGESITNIGKA-SILGAASIGKGLGGML--FSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGFLDSALELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFM 840
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302]) HSP 1 Score: 358.992 bits (920), Expect = 7.959e-111 Identity = 247/755 (32.72%), Postives = 365/755 (48.34%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL---------------------SIFKGKSNLESST--------------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSS-----------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI------GNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENG----------------IPKSIEDHFSRTFRRFSQATSIMPAVDELQ--------LKFNSLKEYSFLKRFNLFLNILKGKDLKT-----NNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
L PEE RWFYK +K +K F GYDSLR+E FR L S G+ + E S E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S SH+ FVVHGIGQ++ G I + ++++ + + +K+++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP L + + DEL + R+L ++++ + + I S T + FK V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + N NP K + D + I+A S V+ G I K + F R S + P+ D L+ ++ + + FL+ + ++ + P N + ++ + L R+D+ L E S Y S +TSHT+YW L++A FL+ M
Sbjct: 150 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGAQARAAGRDGDRVCGPSSSFGEEDEEDSACGFCPRAAGPEPEMEELVTIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSCFRGQQMQENFDIEVSKSLDGKDAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGW-NPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSI-----SQTPAL-----------KFK----------VENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAK-EPTSVSDSENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFM 868
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302]) HSP 1 Score: 348.977 bits (894), Expect = 9.107e-107 Identity = 246/789 (31.18%), Postives = 366/789 (46.39%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL---------------------SIFKGKSNLESST--------------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQY-------------------------------------SCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSS-----------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI------GNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENG----------------IPKSIEDHFSRTFRRFSQATSIMPAVDELQ--------LKFNSLKEYSFLKRFNLFLNILKGKDLKT-----NNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
L PEE RWFYK +K +K F GYDSLR+E FR L S G+ + E S E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q S + + +K + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S SH+ FVVHGIGQ++ G I + ++++ + + +K+++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP L + + DEL + R+L ++++ + + I S T + FK V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + N NP K + D + I+A S V+ G I K + F R S + P+ D L+ ++ + + FL+ + ++ + P N + ++ + L R+D+ L E S Y S +TSHT+YW L++A FL+ M
Sbjct: 150 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGAQARAAGRDGDRVCGPSSSFGEEDEEDSACGFCPRAAGPEPEMEELVTIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSCFRGQQMQENFDIEVSKSLDGKDVVYHLPPFSLPSLFKWRGYKESTDATGLKRKRSQAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGW-NPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSI-----SQTPAL-----------KFK----------VENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAK-EPTSVSDSENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFM 902
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302]) HSP 1 Score: 121.709 bits (304), Expect = 1.506e-31 Identity = 60/141 (42.55%), Postives = 93/141 (65.96%), Query Frame = 2
Query: 620 KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEI--SHGVQSE 1033
+KL S S G ++ RGY E+ +L+DK S SH+ FVVHGIGQ++ G I + ++++ + + +K+++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E GV+S+
Sbjct: 19 QKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDETLKRKGVKSQ 156
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Sec23ip (Sec23 interacting protein [Source:MGI Symbol;Acc:MGI:2450915]) HSP 1 Score: 107.842 bits (268), Expect = 1.892e-23 Identity = 105/377 (27.85%), Postives = 166/377 (44.03%), Query Frame = 2
Query: 95 PSIGENKIEILHPEETRWFY-KSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVV--KRICVPIYWTDSNDNFDIYRGTWFI-ADT---FEPLIENLADAIESQFMMNFLSLQYS-----CLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDD----KQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKF------RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
P + +N+ E + P WFY K VE K ++ FS DSL LE + ++++ E +++ +D DV R+ +YW + + ++ R TWF DT F P E ++ +E+++ + Q+ + N KVI + S+ EW Q+ R + +K RG + SLD+ + + HL F+VHGIG R + ++ V K H R+EFLP+ W + L +D IT R N T++D+L+Y+S Y I V+ E NR++S+F SRNP F+ GKVS+ HSLGS+I +DI+
Sbjct: 255 PFVLQNQYEPVQP---HWFYCKEVEY--KQLWMPFSVLDSLNLEEIY---------NSVQPDPESVVLGTDGGRYDVYLYDRMRKSVYWEE--EPTEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQT--------RPRVVK------------RGIDD--SLDEIPDGEMPQVDHLVFMVHGIGPVCDLRF-RSIIECVDDFRVVSLKLLQTHFKKSVDEGKVSRVEFLPVHWHSALGGHATGVDRNIKKITLPSIGRFRHFTNETLLDVLFYNSPTYCQAIVEKVEVEINRLHSLFMSRNPNFK---GKVSVAGHSLGSLILFDIL 589 HSP 2 Score: 55.4546 bits (132), Expect = 2.563e-7 Identity = 27/58 (46.55%), Postives = 37/58 (63.79%), Query Frame = 2
Query: 1406 FFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKE 1579
FF LGSP+ + L +RG+ +D+ LP C+ FNIYH DPVAYRLEP++ +
Sbjct: 784 FFALGSPIGMLLTIRGVA---RIDEKYRLP--TCKGFFNIYHPLDPVAYRLEPMIAPD 836
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|O46606|DDHD1_BOVIN (Phospholipase DDHD1 OS=Bos taurus OX=9913 GN=DDHD1 PE=1 SV=1) HSP 1 Score: 351.673 bits (901), Expect = 2.120e-107 Identity = 205/549 (37.34%), Postives = 297/549 (54.10%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGK-----------------------SNLES------------------------STEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
L PEE RWFYK +K +K F GYDSLR+E FR L G S++E + E++ V+ L+E DV + C P+YW S D + RG WFI T++PL E ++ IE + + F Q D VS+ + IH+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 163 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQATGARARAQDPDGDHVCGPASPAGPASSSVEDEDEDRVCGFCPRIAGHGREMEELVNIERVCVRGGLYEVDVTQGECYPVYWNQS-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSRFRGQQMQESFDIEVSKPIDGKDAIHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPNFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLREIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQI 687
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NEL9|DDHD1_HUMAN (Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2) HSP 1 Score: 346.665 bits (888), Expect = 2.916e-105 Identity = 203/546 (37.18%), Postives = 295/546 (54.03%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSN--------------------------------LESST------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK--NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
L PEE RWFYK +K +K F GYDSLR+E FR L G +S+T E + V+ L+E DV + C P+YW + D + RG WFI T++PL E ++ IE + + F Q D VS+ + +H+ K S ++W+++ E YLY S R +KL S S G ++ RGY E+ +L+DK S +H+ FVVHGIGQ++ G I + ++++ + + +++++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP + ++LL K +L D + +S E ++D + + E+ ++ T + K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 163 LGPEEVRWFYKE----DKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQA-DKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGW-NP-------------VRLYEQLLQKEEELPD-ERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFK-VENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQI 684
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80YA3|DDHD1_MOUSE (Phospholipase DDHD1 OS=Mus musculus OX=10090 GN=Ddhd1 PE=1 SV=1) HSP 1 Score: 274.633 bits (701), Expect = 9.262e-82 Identity = 158/405 (39.01%), Postives = 226/405 (55.80%), Query Frame = 2
Query: 572 LQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSS-----------DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI------GNRRNPKKPNDLKIPDIKVISATESEVSC 1720
+ E YLY S R +KL S S G ++ RGY E+ +L+DK S SH+ FVVHGIGQ++ G I + ++++ + + +K+++ H T +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ E+ G+Q E NR+YS+FCSRNP FE KGGKVSI++HSLG VI YDI+ W NP L + + DEL + R+L ++++ + + I S T + FK V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +C R+ NI+H +DPVAYRLEPL++K Y I PV I + + + N NP K + D + I+A S V+
Sbjct: 1 MDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHAT---HVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGW-NPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSI-----SQTPAL-----------KFK----------VENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAK-EPTSVSDSENIAAIPSPVTS 374
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8W5R2|SHGR2_ARATH (Phospholipase SGR2 OS=Arabidopsis thaliana OX=3702 GN=SGR2 PE=1 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 4.320e-29 Identity = 103/353 (29.18%), Postives = 165/353 (46.74%), Query Frame = 2
Query: 146 WFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADT---FEPLIENLADAIESQF---MMNFLSLQYSCL-DSNVS-QKNRKVIHAM--KYSNYLIEWYNLQEAYL-----YDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDD--KQSDISHLCFVVHGIGQRLA-GHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDG-GMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
W+ + E SE + S S+ + E S+ +E + VK L+E D+V+R C P+YW + DN + RG WF + P+ E +++ +E + + S Q S L + + Q + +HA+ + W N+ + Y N + R + S K Q+ +R KE+ +DD Q + HL F+VHGIGQ+ ++ +Q ++ +++ H S R+ F+P +WR L L G +D T + R + + TV D+LYY S +Y I V + NR+Y F RNP + GK+SI HSLGSV+ YDI+
Sbjct: 112 WWKEYAECSEGPKLQVNSKKKSIETPS---EASVSSSLYEVEEERVGVPVKGGLYEVDLVRRHCFPVYW--NGDNRRVLRGHWFARKGGLDWLPIPETVSEQLEVAYRNKVWRRRSFQPSGLFAARIDLQGSSLGLHALFTGEDDTWEAWLNVDPSGFSGIVGYTGNGIKLR-RGYAGSYSPKPTQEELRQQKEE-EMDDYCSQVPVRHLVFMVHGIGQKGEKSNLVDDVGNFRQITAALAERHLTSHQLSTQRVLFIPCQWRKGLKLSGEAAVDKCTLDGVRRFREMLSATVHDVLYYMSPIYCQAIIDSVSKQLNRLYLKFLKRNPDYV---GKISIYGHSLGSVLSYDIL 454 HSP 2 Score: 71.633 bits (174), Expect = 1.944e-11 Identity = 38/76 (50.00%), Postives = 46/76 (60.53%), Query Frame = 2
Query: 1397 VDNFFMLGSPLPVFLVLR------GLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
VD FF +GSPL VFL LR G ++N I C+R+FNI+H DPVAYR+EPL+ KEYL PV I
Sbjct: 673 VDTFFAVGSPLGVFLALRNIRLGIGKGKDYWEEENAIEEMPACRRMFNIFHPYDPVAYRVEPLVCKEYLPERPVII 748
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y6Y8|S23IP_HUMAN (SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1) HSP 1 Score: 108.612 bits (270), Expect = 7.627e-23 Identity = 106/375 (28.27%), Postives = 163/375 (43.47%), Query Frame = 2
Query: 95 PSIGENKIEILHPEETRWFY-KSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVV--KRICVPIYWTDSNDNFDIYRGTWFI-ADT---FEPLIENLADAIESQFMMNFLSLQYS-----CLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTS--LDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKF------RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
P + +N+ E + P WFY K VE K ++ FS +DSL LE + ++++ E +++ +D DV RI YW + + ++ R TWF DT F P E ++ +E+++ + Q+ + N KVI + S+ EW Q+ R + +K RG + D + + HL FVVHGIG R + ++ V K H R+EFLP+ W ++L D +D IT R N T++DIL+Y+S Y I V E N ++++F SRNP F KGG VS+ HSLGS+I +DI+
Sbjct: 259 PFLLQNQYEPVQP---HWFYCKEVEY--KQLWMPFSVFDSLNLEEIY---------NSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEE--EPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQT--------RPRVVK------------RGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRF-RSIIECVDDFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDF--KGG-VSVAGHSLGSLILFDIL 593 HSP 2 Score: 62.7734 bits (151), Expect = 1.232e-8 Identity = 29/58 (50.00%), Postives = 41/58 (70.69%), Query Frame = 2
Query: 1406 FFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKE 1579
FF LGSP+ +FL +RG++ +D+N LP C+ FNIYH DPVAYRLEP+++ +
Sbjct: 786 FFALGSPIAMFLTIRGVD---RIDENYSLP--TCKGFFNIYHPLDPVAYRLEPMIVPD 838
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: K1QJ18 (Phospholipase DDHD1 OS=Crassostrea gigas OX=29159 GN=CGI_10003758 PE=4 SV=1) HSP 1 Score: 390.578 bits (1002), Expect = 7.930e-122 Identity = 243/710 (34.23%), Postives = 374/710 (52.68%), Query Frame = 2
Query: 38 SDTDNLSSFFKSQESLEGNPSI--------GENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMS-NHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI-KLLTSEDEIGNRRNPK-----KPNDLKIPD-IKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL 2116
++ DN S F E+ P + + ++ L PEE RWFYK E + F GYDSLR+E ++R L + + +++ I+V+ L++ DV KR C P+YW S D DI +G WF +PL +N IE++ + FL + + Q++R V+H +K++++ IEW + + YLY + + ++ K K G +++RGYK + +DDK +DISHL FV+HGIGQ++ G+I ++ +L++ + K++ + R EFLP+EWR++L LDG M+D ITP +G+R++ NN+ MDILYY+S LY+ EI+H +Q+E NR++ MFC+RNPYF+ GGKVSI+AHSLG+VI YDII W NP I L +D S E ++ ++++ I + T S K ++ KQ P+ T ++N F LGSPL VFL LRG P+ + I+P +C+R+FNIYH DPVAYRLEPL++K Y I P+ I + + E N+ K KP+ KI D +K + ES ED E + + +E+ + + ++ +D+ L++ R+DY L E + +SYIS+LTSHTSYW D ++A F++ + EL
Sbjct: 40 TEDDNTSEFSADSEARATPPLVRLKNPLFPKKEYVDKLRPEEIRWFYKQEGDKE---WTPFIGYDSLRIECRYRALQTVEDEQEIDNDV--ILVRGGLYQVDVAKRRCTPVYW--SGDLSDITQGLWFYEYNGQPLEDNFGVPIETEHVAKFLGHKIE-EEHPSPQRSRPVLHRIKFTDFYIEWNSPNDTYLYSEAASSRFVRGFKKKLGMQKAGTRLLRGYKYEAVMDDKPADISHLVFVIHGIGQKMETGNIVKRAKELREKVSQMKAKHFCLIENTSQRAEFLPVEWRSSLKLDGDMVDLITPHKMRGMRSLLNNSAMDILYYTSPLYRSEITHSLQNELNRLFEMFCARNPYFQVNGGKVSIVAHSLGAVISYDIITGW-NP-IQL-----YDQFVNSVIEGEQQDSDSSEIKEEIHEARQKA--TAVESILKDVQEKHKQKCGPTLSFT---------IENMFCLGSPLAVFLALRGFRPQGKGTLDHIMPSSLCKRLFNIYHPYDPVAYRLEPLILKHYSTIMPLPIHRFDIKQKEPYNQMKTKAYAAFKPSAEKITDKVKWLKGKES-----EDMSAELKMLEKMEEDVQEIEKSIKERKEVLQEIDQTDLEY-----------------------------------------------RIDYQLREASFSNSYISMLTSHTSYWTDRDVAFFVLSHIHPEL 671
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A267G2H6 (DDHD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026674g1 PE=4 SV=1) HSP 1 Score: 394.815 bits (1013), Expect = 5.721e-121 Identity = 214/553 (38.70%), Postives = 325/553 (58.77%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL---------SIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDN-------FDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNR---------------KVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDI---------IDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKP 1660
L PEE RWFY+ E+ EK F+GYDSLRLE K REL + + +S TEKI+V+ LFEAD+ R C PIYW++ N + RGTWF + ++PL E+LA IE++ + F L+Y +S V ++ + IH+++ ++ + WY+L++ +LY ++ + ++KL + + G ++VRGYK++ +++K +DI+HL FV+HGIGQ++ G I + + L+Q+ + + KK++ ++ R+EFLP+EWR+ L LDG +DSITP + +GLRT+ N++ MD+LYY+S LY+ EI+HG+Q+E +R+YSMFC+R+PYFE GGKVS+I HSLG VI YDI+ W NP + L + Y L D N+ C++ + + ++S K+ K N +NF+ ++N F LGSPL VFL LRG+ PK Q DI+PK + RI+NIYH +DPVAYRLEPL++K Y I PVHI + + ++ P++P
Sbjct: 90 LRPEEIRWFYQ--EEGEKKWLP-FNGYDSLRLECKHRELLCTAAGAAAAAPATGGSGDSHTEKILVRGGLFEADIAARSCRPIYWSEMRVNKMSVKQTAVLTRGTWFRENGWQPLPEDLAAQIEAEHLAKFEGLRYE--ESPVCREGGSSGGGGGASGSSKSKEAIHSLRLTDCHVNWYDLRQVHLYQDSTSRFILQKLGVQ---RTGARLVRGYKDEAKVEEKLADITHLVFVIHGIGQKMRTGAIVKCAFDLRQTCERIKKKFFPDLDSANQRVEFLPVEWRSALTLDGDTVDSITPPNIRGLRTLLNSSAMDVLYYTSPLYRAEITHGLQTELSRLYSMFCARHPYFEPAGGKVSVIGHSLGCVITYDIVMGW-NP-MQLYDQFVHSY--------------LNDKSNDREECQQVLKELDEARKKVTELEYSLLSMAEKQHKSANSCTNFR----------LENLFCLGSPLAVFLALRGIRPKGNGTQEDIVPKSIVNRIYNIYHPADPVAYRLEPLILKHYSTIQPVHIHRVDAMNKPPYHTLPQEP 608
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A0L8GHQ7 (DDHD domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033258mg PE=4 SV=1) HSP 1 Score: 387.111 bits (993), Expect = 4.539e-120 Identity = 229/563 (40.67%), Postives = 329/563 (58.44%), Query Frame = 2
Query: 116 IEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEK--IIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSC-LDSNVSQK-NRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMS-NHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQN---DILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEV-----SCFEDEDEENGIPKSI 1762
IE LHPEE RW Y+ K + + F GYDSLR+E ++RELS+ S+L K I+V+ L+E DVV R C P++WT D D+ RG WF DT++PL E+ + IES + FL +Y C V+ K R+VIH + +S+ +EW N E Y++ ++ + ++ + + K G K+ RGY + +DDK DI+HL FVVHGIGQ++ G+I ++C +L++S + + KK + S R+EFLP+EWR++L LDG ++ ITP KGLRTI N++ MDILYY+S LY+ EI+HG+QSE NR+YS+FC RNPYF GGK+SI AHSLG+VI YDII SW NP I L + + ++L LTD+ + + E S S +++++ + F+ V+N F LGSPL VFL LRG+ P + D N +++P H+C R+FNIYH +DP+AYR+EPL+ K Y I PV I+ D R + D V S++E + S E E E + +PK+I
Sbjct: 135 IEELHPEEVRWMYRHAGKKK---WTPFIGYDSLRIEFRYRELSV----SSLSEDKLKDMIVVRGGLYEVDVVARKCYPLFWT--GDTADVLRGIWFYDDTWQPLEEDTSIRIESDHLGKFLGKKYPCDFSETVNLKVARQVIHHIAFSDCHVEWRNATEVYMFSDSTPSKIVRSVSQTLGFQKSGTKLCRGYCNEARMDDKPPDITHLVFVVHGIGQKMDTGNIIKRCNELRESIERLKKKNFPNLDQSNQRVEFLPVEWRSSLQLDGDTVELITPHSVKGLRTILNSSAMDILYYTSPLYRSEITHGLQSEINRLYSVFCLRNPYFISAGGKISIAAHSLGAVITYDIITSW-NP-IKLYDQFVASLIDEKREQLQDSTHLLTDMDSARARVSE------IESQLSSLQEKQQKGSQALKFR----------VENLFCLGSPLAVFLTLRGV-PLHGCDNNGQPNVIPSHLCHRLFNIYHPADPIAYRIEPLIYKHYASILPVDIQRF---DAPLKRPYSECSGRGSTSDTLVDSSSEHSIASIPESSTETEVESSSLPKTI 666
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A0L8GHR9 (DDHD domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033258mg PE=4 SV=1) HSP 1 Score: 384.8 bits (987), Expect = 5.142e-119 Identity = 232/568 (40.85%), Postives = 328/568 (57.75%), Query Frame = 2
Query: 116 IEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEK--IIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSC-LDSNVSQK-NRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMS-NHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSS---DELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLK--REKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQN---DILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEV-----SCFEDEDEENGIPKSI 1762
IE LHPEE RW Y+ K + + F GYDSLR+E ++RELS+ S+L K I+V+ L+E DVV R C P++WT D D+ RG WF DT++PL E+ + IES + FL +Y C V+ K R+VIH + +S+ +EW N E Y++ ++ + ++ + + K G K+ RGY + +DDK DI+HL FVVHGIGQ++ G+I ++C +L++S + + KK + S R+EFLP+EWR++L LDG ++ ITP KGLRTI N++ MDILYY+S LY+ EI+HG+QSE NR+YS+FC RNPYF GGK+SI AHSLG+VI YDII SW N + QF +S + L + K LQ++ + + S +S L +EKQ K V+N F LGSPL VFL LRG+ P + D N +++P H+C R+FNIYH +DP+AYR+EPL+ K Y I PV I+ D R + D V S++E + S E E E + +PK+I
Sbjct: 135 IEELHPEEVRWMYRHAGKKK---WTPFIGYDSLRIEFRYRELSV----SSLSEDKLKDMIVVRGGLYEVDVVARKCYPLFWT--GDTADVLRGIWFYDDTWQPLEEDTSIRIESDHLGKFLGKKYPCDFSETVNLKVARQVIHHIAFSDCHVEWRNATEVYMFSDSTPSKIVRSVSQTLGFQKSGTKLCRGYCNEARMDDKPPDITHLVFVVHGIGQKMDTGNIIKRCNELRESIERLKKKNFPNLDQSNQRVEFLPVEWRSSLQLDGDTVELITPHSVKGLRTILNSSAMDILYYTSPLYRSEITHGLQSEINRLYSVFCLRNPYFISAGGKISIAAHSLGAVITYDIITSW--------NPIKLYDQFVASLIKQYMELIDEKREQLQDSTHLLTDMDSARARVSEIESQLSSLQEKQQKGSQALKF--------RVENLFCLGSPLAVFLTLRGV-PLHGCDNNGQPNVIPSHLCHRLFNIYHPADPIAYRIEPLIYKHYASILPVDIQRF---DAPLKRPYSECSGRGSTSDTLVDSSSEHSIASIPESSTETEVESSSLPKTI 673
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A2T7P027 (DDHD domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_14447 PE=4 SV=1) HSP 1 Score: 385.956 bits (990), Expect = 5.450e-119 Identity = 244/701 (34.81%), Postives = 376/701 (53.64%), Query Frame = 2
Query: 116 IEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMS-NHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLK---REKQP---NFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDE---IGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSR-----------------TFRRFSQATSI-MPAVDELQLKFNSLKEYSFLKR----FNLFLNILKGKDLKTNNIPPG-NNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL 2116
++ L PEE RWF++S E ++K + F GYDSLR+E ++R L + +L+++ E+I+V L+E DVVK+ C P+YW S D DI RG WF T++PL + A IE + +FL + + ++ ++ VIH +K+ + ++W E Y++ ++ + M+ + S K G ++ RGY+ + +DDK +DI+HL FV+HGIGQ++ +G I R C L+ S+ +K + +S R EFLP+EWR++L LDG ++SITP KG+R I N++ MDILYY+S LY+ EI+H +++E R+Y MFC+R+PYFE GGKVSI+AHSLG+VI YDII W + + QF +S + + D Q+N E++ T K L+ +EKQ + P V+N F +GSPL VFL LRG+ P+ ++P C+R+FNIYH SDPVAYRLEPL++K Y I P+ I L ++ +G R P I ++ +C ED + +G + +E+ + +F A SI + D+L + K+ + L +L+ D + + P + + L RLDY L E + +SY+SLLTSHTSYW ++A FL+ + +L
Sbjct: 50 VDKLRPEEIRWFHRS-ENAKK--WAAFIGYDSLRIECRYRALEV-DSNGDLDAN-ERILVLGGLYEVDVVKKKCFPVYW--SGDVSDIIRGAWFYDCTWQPLEDRYAILIEEDHITHFLGQRLESECTQTTKGHKPVIHNIKFREFHVDWNATNEVYMFSESTSSKFMRSVGKSLGWQKSGTRLHRGYRVEAVMDDKPADITHLVFVIHGIGQKMDSGRIVRCCKDLRGCVVSIERKLFPDLGSSNQRAEFLPVEWRSSLKLDGDTVESITPHKMKGVRNILNSSAMDILYYTSPLYRSEITHSLRAELVRLYHMFCNRHPYFEANGGKVSIVAHSLGNVITYDIITGW--------DPIRLYDQFLTS----VFEGEQVDAQSNNPQVLEELGTTHKRVMELEVLRKHLKEKQAIEESLPF------------QVENLFCVGSPLAVFLALRGIRPQGTGSHAHLMPTSKCRRLFNIYHPSDPVAYRLEPLVLKHYATIMPLPIHLHSASHHSSYVGMPRKAYAPFQGSADGI-------AQKTCTEDGQDSSGKEECLENFVTAGTSHKTEAKSDGKVKGFSFAFLKVANSIGFSSPDKLTYEVGRWLADRKSKKDDNEMSAELKMLQSLDHEAQHAQAAIQYPEPKDIDKTELEYRLDYQLRERSMENSYVSLLTSHTSYWTSRDVALFLLVHLFPQL 712
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1b (DDHD domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-040724-18]) HSP 1 Score: 331.643 bits (849), Expect = 1.084e-101 Identity = 235/759 (30.96%), Postives = 362/759 (47.69%), Query Frame = 2
Query: 2 MDRRLGSYEIIFSDTDNLSSF-FKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFREL-------------------------SIFKGKSNLESST--------------------EKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQ----YSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVK-NVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLL-TSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM 2104
+ RL + S TD L + + S G+ + L PEE RWFYK +K +K F G+DSL++E +R+L + K E+S E + V+ L+E DV ++ P+YW + + + RG WF T+ PL E +D IE + + F Q + + ++ IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ + +D +H+ FVVHGIGQ++ G I R ++ + + + +K+++ T +EFLP+EWR+ L+LDG +DSITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+Y++FCSRNP FE K GKVSI++HSLG VI +DI+ W + + F +Q ++ D + + R+ CEE + + H R+ + F + +K V+NFF +GSPL VFL LRG+ P N Q+ ILP+ +CQR+ NI+H +DPVAYRLEPL++K Y I PV I TS ++ P N LK + V + C P H+ + +A SIM A + + F + + ++ K + + M+N L R+D+ L E S Y S +TSHT+YW ++A FL+ M
Sbjct: 47 LQSRLPGLQHGLSGTDYLDVLGYGPRRSRAGSSRHRGEVVTELGPEEVRWFYKE----DKRTWKPFVGHDSLQIELTYRKLCELNPGKASEQDEWEELGGSGGDSEGVEGQKGQTEASVSKEVAGPAEEIDVDSIDIGVEAVCVRGGLYEVDVKEKESYPVYW-NQQERIPVMRGQWFTDGTWLPLEEEDSDLIELEHLSCFRGHQMKDTFETEAVTTAVDSKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEAAPEDTPPAATHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEEKHFSDRTTE--HVEFLPVEWRSKLSLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDEITRGLTKELNRLYTLFCSRNPEFEEK-GKVSIVSHSLGCVITFDIMTGW--------DPVRFHHQ-EAPDAMETEQRR--------RGCEEQRL--LEELHLTRMRLRDLEDQFQGLKMSSSRTSPPLKFKVENFFCMGSPLAVFLALRGIRPGNNGTQDHILPRSICQRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSSPTPYDQIRPTLLNPLKE-SVSVSDSESLPSPCTS--------PPQNRRHYGESITNLGKA-SIMGAAS-IGKGIGGIFFSRFSRSSGQMEDKVEDKREGSAGCMSQSTSTIMDNSTFELDRRIDFELREGLVESRYWSAVTSHTAYWCSHDIALFLLTFM 767
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:103023862]) HSP 1 Score: 321.242 bits (822), Expect = 4.487e-97 Identity = 175/464 (37.72%), Postives = 269/464 (57.97%), Query Frame = 2
Query: 275 STEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQKN---RKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWG----------NPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
S E + V+ L++ DV + C P+YW + D + RG WFI T+ P+ E+ +D IE + + +F Q +++V K + IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ SL+DK +H+ FVVHGIGQ++ I + L+++ + + +K++A H ++ +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+Y++FCSRNP FE KGGKVSII+HSLG VI YDI+ W P+ +S++ + +++ L ++L +L++ + L+ K P+ FK V+N+F +GSPL VFL LRG+ P + Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 246 SVEAVCVRGGLYQVDVREMECYPVYW-NQQDRIPVMRGQWFIDGTWMPMEEDESDLIEREHLTSFRGQQMQDSFENDVVVKTVDTKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLEDKPPLTTHIVFVVHGIGQKMDKDRIIKNTGMLREAVRKMEEKHFADH--TEEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYALFCSRNPEFEEKGGKVSIISHSLGCVIAYDIMTGWDPVRFCLLEQQEPDEEEMRWMSYE-ERHLLEQVHLTRQRLRELEDKLQG-----------------LEASKPLQLPALKFK----------VENYFCMGSPLAVFLALRGIRPGSTGYQDHIMPKSICKRLFNIFHPTDPVAYRLEPLVLKHYSNIAPVQI 678
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:103023862]) HSP 1 Score: 310.842 bits (795), Expect = 5.564e-93 Identity = 176/496 (35.48%), Postives = 269/496 (54.23%), Query Frame = 2
Query: 275 STEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQ---------------------------------YSCLDSNVSQKNRK---VIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWG----------NPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
S E + V+ L++ DV + C P+YW + D + RG WFI T+ P+ E+ +D IE + + +F Q +S ++ RK IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ SL+DK +H+ FVVHGIGQ++ I + L+++ + + +K++A H ++ +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+Y++FCSRNP FE KGGKVSII+HSLG VI YDI+ W P+ +S++ + +++ L ++L +L++ + L+ K P+ FK V+N+F +GSPL VFL LRG+ P + Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 246 SVEAVCVRGGLYQVDVREMECYPVYW-NQQDRIPVMRGQWFIDGTWMPMEEDESDLIEREHLTSFRGQQMQDSFENDVVVKTVDTKDALSHFPPFYLPFLFKWSGYQTSAKSHKRKRCQAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLEDKPPLTTHIVFVVHGIGQKMDKDRIIKNTGMLREAVRKMEEKHFADH--TEEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYALFCSRNPEFEEKGGKVSIISHSLGCVIAYDIMTGWDPVRFCLLEQQEPDEEEMRWMSYE-ERHLLEQVHLTRQRLRELEDKLQG-----------------LEASKPLQLPALKFK----------VENYFCMGSPLAVFLALRGIRPGSTGYQDHIMPKSICKRLFNIFHPTDPVAYRLEPLVLKHYSNIAPVQI 710
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:103023862]) HSP 1 Score: 294.278 bits (752), Expect = 1.274e-87 Identity = 186/575 (32.35%), Postives = 301/575 (52.35%), Query Frame = 2
Query: 5 DRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEI---LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIF----------KGKSNLESSTEKIIVKSDLFEADVVKRI--CVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRK----------VIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWG----------NPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
D S +++S++D S +S++ + +++E+ L EE RWFYK +K +K F+G+DSL +E +R+ + + + + + A+V+ R+ C P + + G +E A ES ++ +S++ C+ + Q + + IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ SL+DK +H+ FVVHGIGQ++ I + L+++ + + +K++A H ++ +EFLP+EWR+ L LDG +DSITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+Y++FCSRNP FE KGGKVSII+HSLG VI YDI+ W P+ +S++ + +++ L ++L +L++ + L+ K P+ FK V+N+F +GSPL VFL LRG+ P + Q+ I+PK +C+R+FNI+H +DPVAYRLEPL++K Y I PV I
Sbjct: 94 DDGAASDHLLYSESDGNVSPLESRKRARSGAASSRHRLEVVTELGAEELRWFYKE----DKKTWKPFAGHDSLNIELMYRKFCELNPVELDQDHNEDQHQDQEGASAALSEEGKHAAEVMDRVGTCGP-----GSAAGQVEEGA---------SVEAPESAGESDVDVS-ISVEAVCVRGGLYQVDVREMECYPVYWNPIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLEDKPPLTTHIVFVVHGIGQKMDKDRIIKNTGMLREAVRKMEEKHFADH--TEEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYALFCSRNPEFEEKGGKVSIISHSLGCVIAYDIMTGWDPVRFCLLEQQEPDEEEMRWMSYE-ERHLLEQVHLTRQRLRELEDKLQG-----------------LEASKPLQLPALKFK----------VENYFCMGSPLAVFLALRGIRPGSTGYQDHIMPKSICKRLFNIFHPTDPVAYRLEPLVLKHYSNIAPVQI 619
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: sec23ip (SEC23 interacting protein [Source:NCBI gene;Acc:103028985]) HSP 1 Score: 117.857 bits (294), Expect = 1.113e-26 Identity = 102/369 (27.64%), Postives = 163/369 (44.17%), Query Frame = 2
Query: 122 ILHPEETRWFY-KSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSD--LFEADVVKRICVPIYWTDSNDNFDIYRGTWFI---ADT-FEPLIENLADAIESQFMMNFLSLQYS-----CLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSK------FRIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGN 1162
+ P + WFY K VE K ++ FS DSLRLE F ++++ E +I+ +D ++ + R +YW + + ++ R TWF AD+ F P E +D +E+++ + Q+ + N KVI + S EW Q D + +K+ +H + D + + HL F+VHGIG R + +++V K H R+EFLP+ W T L+ D +D IT LR N T++D+L+Y+S Y I V SE NR++++F RNP F+ G VS+ HSLGS+I +D++ + N
Sbjct: 246 VYEPVQPHWFYCKQVEA--KKVWLPFSILDSLRLEETF---------NSIQPDPENVIICTDGGRYDVQLYDRTRTSVYWEE--EPTEVRRCTWFYKGDADSRFIPYSEEFSDKLEAEYKKAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSAMPDEWGTTQ-----DGQTRPRVVKRGVDDDHDEVP-------------DGEMPQVDHLVFMVHGIGPVCDLRF-RSMVECVDDFRTVSLKLLQSHFKKAQDERIISRVEFLPVHWHTALHGDATGVDRRIKKITLPSTGRLRHFTNETLLDVLFYNSPTYCQTIMDTVASEINRLHALFMQRNPDFK---GAVSVAGHSLGSLILFDLLSNQKN 579 HSP 2 Score: 64.6994 bits (156), Expect = 2.898e-10 Identity = 32/68 (47.06%), Postives = 48/68 (70.59%), Query Frame = 2
Query: 1403 NFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
NFF LGSP+ +FL +RG+ +++N LP C+ FNIYH DPVAYR+EP+++ + +++DPV I
Sbjct: 756 NFFALGSPIGMFLTVRGVE---RIEENYRLP--TCKGFFNIYHPLDPVAYRIEPMILPD-VELDPVLI 817
BLAST of DDHD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010367.1 (pep scaffold:Pmarinus_7.0:GL490372:1378:4627:-1 gene:ENSPMAG00000009389.1 transcript:ENSPMAT00000010367.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 99.3673 bits (246), Expect = 5.006e-24 Identity = 42/76 (55.26%), Postives = 54/76 (71.05%), Query Frame = 2
Query: 1379 WKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
W V+NFF +GSPL VFL LRG+ P + + ILPK VC+R+FNI+H +DPVAYRLEPL+++ Y I PV I
Sbjct: 4 WMSGVKVENFFCMGSPLAVFLALRGVRPGSSGSPHHILPKSVCRRLFNIFHPTDPVAYRLEPLILRHYSAIQPVQI 79
BLAST of DDHD domain-containing protein vs. Ensembl Yeast
Match: DDL1 (DDHD domain-containing phospholipase A1; mitochondrial matrix enzyme with sn-1-specific activity, hydrolyzing cardiolipin, PE, PC, PG and PA; implicated in remodeling of mitochondrial phospholipids; antagonistically regulated by Aft1p and Aft2p; in humans, mutations in DDHD1 and DDHD2 genes cause specific types of hereditary spastic paraplegia, while DDL1-defective yeast share similar phenotypes such as mitochondrial dysfunction and defects in lipid metabolism [Source:SGD;Acc:S000005548]) HSP 1 Score: 74.7146 bits (182), Expect = 2.738e-14 Identity = 53/170 (31.18%), Postives = 78/170 (45.88%), Query Frame = 2
Query: 710 DISHLCFVVHGIGQRL---------AGHINRQCYKLKQSYKSVLKKY---YAPHVTSKFRIEFLPIEWRTNL------------NLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
D+ +L VHGIGQ L A +N +K+ Y + K AP S ++ LPI WR ++ N D + +T LR + + ++DIL Y YQ I V S+ N+ Y +F NP F+ GKV ++ HSLGS+I +DI+
Sbjct: 345 DVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFD---GKVHLVGHSLGSMILFDIL 511 HSP 2 Score: 51.6026 bits (122), Expect = 4.225e-7 Identity = 24/76 (31.58%), Postives = 46/76 (60.53%), Query Frame = 2
Query: 1397 VDNFFMLGSPLPVFLVLR----GLNPK--NVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
VDN F +GSP+ + +++ G P+ N +++ + + C+ I+N+YH DP++YR+EPL+ KE + ++
Sbjct: 523 VDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYL 598
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Match: EDO40974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5H0]) HSP 1 Score: 266.929 bits (681), Expect = 9.144e-81 Identity = 183/532 (34.40%), Postives = 279/532 (52.44%), Query Frame = 2
Query: 536 MKYSNYLIEWYNLQEAYLY--DMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSE--DEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPP--GNNPRE-MNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMI 2107
++ Y +EW ++ + +LY D+ S R K+ S+ G +I RGY +D +ISHL FV+HGIGQ L +I + + S + V +K P R+EF P+EWR++L LD G ID+ITP GLR + N T+MDI+YY+S Y+ EI G++ E NR+YS+FC RNP F+ K GKVSIIAHSLGSVI YDI+ W +L++ F + L+N + L++ I D + ST E + FK V+N F +GSPL VFL LRGL P++ V ++ +LPK VC+++ NIYH +DPVAYR+EPL+ +EY + P+ + S + ++ ++ K + KV G KS E+ SR+ S A+ DE+ + +S+ + + + K K+ K+ I G++ R+ + ++ LS+RLDY L E S+Y S +TSH SYW ++A+F+++ +
Sbjct: 4 LQLKGYYVEWKDVTDVWLYWDDIKSRIIRGVGTKIGLGSQ-GVQIHRGYHTDAVPEDCPPEISHLVFVIHGIGQLLHMSNIVKSATDFRSSAEKVHEKN-IPGFPRGQRVEFFPVEWRSSLKLDDGAIDAITPASVSGLRKVLNITMMDIMYYTSPFYRYEIISGLREELNRLYSLFCERNPSFQAKQGKVSIIAHSLGSVIMYDILSLWDTEIRHLSDQEKAGTGFLTESFSFLRNLE-AKLKSQIE------FDQNRRGENGSTA--EDVCQYALKFK----------VENLFSVGSPLAVFLTLRGLRPQDDV-EDHVLPKSVCKKMLNIYHPADPVAYRMEPLISEEYSSVPPIQLHRFDSHKLGYLEEKKPARESGGWKFFNYKV------------------GYSKSSEEPRSRS---GSTASDSDAPEDEIVIVGHSVPQGG--REDQCDGDRGKAKEKKSGWISSWFGSSQRKSVESDGQYLSDRLDYVLREGYMESNYWSAVTSHVSYWTSSDVARFVLENTL 490
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Match: EDO37134 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGQ9]) HSP 1 Score: 105.531 bits (262), Expect = 1.976e-23 Identity = 109/390 (27.95%), Postives = 175/390 (44.87%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSD--LFEADVVKRICVPIYWTDSNDNFDIYRGTWFIAD----TFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKM---SNHSKFGQKIVR-GYK--EKTSLDDKQSDISHLCFVVHGIGQ----RLAGHINRQCYK-LKQSYKSVLKKYYAPHVTSKF--RIEFLPIEWRTNLNLDGGMID----SITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDEL 1225
+ P WFY E ++ FS DS LE +F + ++ E IV +D ++ +V +R+ +YW + D + R TWF P E +A +E++F YS + N Q RK++ + S Y++ L++ N M + S + K+VR G E+ D + I HL FV+HGIG R I +C L+ S+L +++ + RIE+LP++W L+ D +D SI+ K LR N+T++DIL+Y+S Y I V SE + ++F RNP F+ G++S+ HSLGS I +DI+ +PN + S Q +S ++
Sbjct: 17 VEPVRPHWFYMK----ENRVWMPFSHIDSEALEHEFSK----------PTTKEDRIVPTDGGRYDVNVDERVRRAVYWEE--DVSVVRRCTWFFKGDGGVKLVPYKEEMAATLEAEF--------YSAVRQN--QWPRKIV--ISDSEYIL---------LHNTNVMVHFQTCGPTDWSGEDSGWRPKVVRRGVADIEEDIEDGEGHQIDHLVFVIHGIGPIADLRFRNII--ECIDDLRMVTLSMLNEHHQELAKGRTIGRIEYLPVQWHDKLHNDSNGVDERLHSISLKSISKLRDFTNSTLLDILFYTSPTYCQTIVDTVGSEMTNLLALFRKRNPSFK---GQISVCGHSLGSSIMFDILYHQQDPNATKSAKQSPPAQQHNSTQM 364 HSP 2 Score: 61.2326 bits (147), Expect = 1.105e-9 Identity = 31/68 (45.59%), Postives = 46/68 (67.65%), Query Frame = 2
Query: 1406 FFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIK 1609
F LGSP+ +F+ +RG++ V + LP CQ++FNI+H DPVAYRLEPL+ +++ DP+ IK
Sbjct: 514 LFALGSPIGMFMTVRGVDQ---VGPDFKLP--TCQKVFNIFHPFDPVAYRLEPLVDSTFVK-DPIMIK 575
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Match: EDO41887 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S326]) HSP 1 Score: 54.299 bits (129), Expect = 1.706e-7 Identity = 74/324 (22.84%), Postives = 128/324 (39.51%), Query Frame = 2
Query: 713 ISHLCFVVHGIGQRLAGHINRQ----CYKLKQSYKSVLKKYYAPHVTS-KFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNT------------VMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKG--GKVSIIAHSLGSVICYDII-------RSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
I+ L VVHG Q G N+ C LK+S+++V+ +Y V R+ P LN M+ + P T N+ + ++ SS +Y +I + + N +Y F + E G G+V+++ +G+++ YD + RS P + +S E L + + I KHS +L + P+ S F V FF GSP+ + L R + ++ P+ C + +N++H DP A R+EPL++ ++ I PV++
Sbjct: 483 ITTLLLVVHGGSQLDWGQDNQSKHVDCELLKESFQAVINAHYKGAVGRIAIRLVACPSICSKALN----MLSQLCPYSETDSDTASCNSGFSPISSSFPISAIPLMVSSSPVYD-DIVSAMIAATNIVYQEFLRSD---EGHGFSGEVNLLGDCMGTLLAYDALCGTFFRDRSTSIPLNSSFSSNHSSNSLNGEHEQTL------NASPRLERKPRRIKHDNKHSFDAMSLSLDSIPDRDSTFDF--------PVSKFFAFGSPIGLVLAYRKFIQGD--EEKAAPPRPSCNQFYNLFHPFDPSASRIEPLILPQFSHIIPVNV 782
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:101163939]) HSP 1 Score: 324.709 bits (831), Expect = 1.754e-98 Identity = 202/565 (35.75%), Postives = 296/565 (52.39%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRE--------------------------------------------LSIFKGKSN--------LESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYS-CLDSNVSQK---NRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSF----DYQFKSSDE--LL--LKN--RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
L PEE RWFYK +K +K F G+DSL++E FR+ S +G+ + +E + E + V+ L+E D+ ++ C P+YW D+ + RG WFI T+ PL E +D IE + + +F Q +++++ K ++ IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ S +D+ +H+ FVVHGIGQ++ G I + L++ + + K+++ H +EFLP+EWR+ L LDG ++SITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE KGGKVSI+AHSLG VI YDII W L + D ++ S +E LL LKN +L DL+N + E +P+ P K V+NFF +GSPL VFL LRG+ P Q+ ILP +C R+FN++H +DPVAYRLEPL++K Y I PV I
Sbjct: 129 LVPEEVRWFYKE----DKKTWKPFLGHDSLKMELMFRKYCELNPSCSAAVRRKVSGERRESGSTGPESPEPNGAAVPGETASCSAREGRGSSDERDPDGIEINVEPVCVRGGLYEVDIKEKECFPVYWKQ-QDHIPVMRGQWFIDGTWLPLEEEESDLIEEEHLNHFRGQQMQDTIETDLVVKTVDSKDAIHSLKLSRTHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASPEDRPPHTTHIVFVVHGIGQKMDQGRIIKNTGMLREGVRKMEDKHFSKHKDE--HVEFLPVEWRSKLTLDGDTVESITPDKVRGLRDLLNSSAMDIMYYNSPLYRDEITKGLTQELNRLYSLFCSRNPEFEEKGGKVSIVAHSLGCVITYDIITGWDPVRFCLQEHRAVEEETDLRWMSYEEKQLLQQLKNTRSRLLDLENQLVALE------------------ASRPSVPPALKF--------KVENFFCMGSPLAVFLALRGIRPGISCHQDHILPTSICSRLFNVFHPTDPVAYRLEPLILKHYSNIAPVQI 660
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1b (phospholipase DDHD1 [Source:NCBI gene;Acc:101171796]) HSP 1 Score: 318.931 bits (816), Expect = 4.032e-97 Identity = 195/557 (35.01%), Postives = 306/557 (54.94%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELS--IFKG-----------------KSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQ---YSCLDSNVSQKNRK-VIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLL-TSEDEIGNRRNPKKPNDLKIPDIKVISATE 1705
L PEE RWFYK +K +K F+G DSL++E +R + + G KS + E + V+ L+E + ++ C P+YW + ++ + RG WF+ T+ PL E ++ IE + + +F Q S +++ S + K ++++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ ++ S+ +H+ FVVHGIGQ++ G I R ++ + + + ++++ T +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE K GKVSI+AHSLG VI +DI+ W +P + ++ D + + R+L + + D+ D F+ T S++ P+ FK V+NFF +GSPL VFL LRG+ P N Q+ IL +C+R+FN++H +DPVAYRLEPL++K Y I PV I T+ + N+ P + N +K D +S E
Sbjct: 110 LGPEEIRWFYKE----DKRTWKPFAGTDSLKIERLYRRRTEQLDPGSDPAGGDGEQNPVPEEVKSPSDVKAEAVCVRGGLYEVHIREKECCPVYW-NQQESIPVMRGQWFVDGTWLPLEEEDSNPIEMEHLSHFRGQQMRDVSEVETAPSTVDSKDAVYSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLRRGYFEEAVPEETPSETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEERHFPDRTTE--HVEFLPVEWRSKLYLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDEITRGLTQELNRLYSLFCSRNPDFE-KNGKVSIVAHSLGCVITFDIMTGW-DP-VRFHHQQMLDPEKTKIRWPSEEERQLQEQLRVLRLRLRDLEDQFRGLQTSSSVA------VPALKFK----------VENFFCMGSPLAVFLALRGIRPGNNTMQDHILSTSICKRLFNLFHPTDPVAYRLEPLILKHYSNIAPVQIDWYNTTSPTLYNQIRPTRLNLMK--DTSFVSEAE 638
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1b (phospholipase DDHD1 [Source:NCBI gene;Acc:101171796]) HSP 1 Score: 318.931 bits (816), Expect = 4.789e-97 Identity = 195/557 (35.01%), Postives = 306/557 (54.94%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELS--IFKG-----------------KSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQ---YSCLDSNVSQKNRK-VIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPS-NFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLL-TSEDEIGNRRNPKKPNDLKIPDIKVISATE 1705
L PEE RWFYK +K +K F+G DSL++E +R + + G KS + E + V+ L+E + ++ C P+YW + ++ + RG WF+ T+ PL E ++ IE + + +F Q S +++ S + K ++++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ ++ S+ +H+ FVVHGIGQ++ G I R ++ + + + ++++ T +EFLP+EWR+ L LDG +DSITP +G+R + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE K GKVSI+AHSLG VI +DI+ W +P + ++ D + + R+L + + D+ D F+ T S++ P+ FK V+NFF +GSPL VFL LRG+ P N Q+ IL +C+R+FN++H +DPVAYRLEPL++K Y I PV I T+ + N+ P + N +K D +S E
Sbjct: 110 LGPEEIRWFYKE----DKRTWKPFAGTDSLKIERLYRRRTEQLDPGSDPAGGDGEQNPVPEEVKSPSDVKAEAVCVRGGLYEVHIREKECCPVYW-NQQESIPVMRGQWFVDGTWLPLEEEDSNPIEMEHLSHFRGQQMRDVSEVETAPSTVDSKDAVYSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLRRGYFEEAVPEETPSETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEERHFPDRTTE--HVEFLPVEWRSKLYLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDEITRGLTQELNRLYSLFCSRNPDFE-KNGKVSIVAHSLGCVITFDIMTGW-DP-VRFHHQQMLDPEKTKIRWPSEEERQLQEQLRVLRLRLRDLEDQFRGLQTSSSVA------VPALKFK----------VENFFCMGSPLAVFLALRGIRPGNNTMQDHILSTSICKRLFNLFHPTDPVAYRLEPLILKHYSNIAPVQIDWYNTTSPTLYNQIRPTRLNLMK--DTSFVSEAE 638
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:101163939]) HSP 1 Score: 318.546 bits (815), Expect = 6.439e-96 Identity = 202/599 (33.72%), Postives = 292/599 (48.75%), Query Frame = 2
Query: 125 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRE--------------------------------------------LSIFKGKSN--------LESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLI-----------------ENLADAIESQ---------------------FMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYD--MNSMAYRM--KKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSF----DYQFKSSDE--LL--LKN--RKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
L PEE RWFYK +K +K F G+DSL++E FR+ S +G+ + +E + E + V+ L+E D+ ++ C P+YW D+ + RG WFI T+ PL + + D IE+ F+ + Q S +K + IH++K S ++W+++ E YLY S R +KL S S G ++ RGY E+ S +D+ +H+ FVVHGIGQ++ G I + L++ + + K+++ H +EFLP+EWR+ L LDG ++SITP +GLR + N++ MDI+YY+S LY+ EI+ G+ E NR+YS+FCSRNP FE KGGKVSI+AHSLG VI YDII W L + D ++ S +E LL LKN +L DL+N + E +P+ P K V+NFF +GSPL VFL LRG+ P Q+ ILP +C R+FN++H +DPVAYRLEPL++K Y I PV I
Sbjct: 129 LVPEEVRWFYKE----DKKTWKPFLGHDSLKMELMFRKYCELNPSCSAAVRRKVSGERRESGSTGPESPEPNGAAVPGETASCSAREGRGSSDERDPDGIEINVEPVCVRGGLYEVDIKEKECFPVYWKQ-QDHIPVMRGQWFIDGTWLPLEEEESDLIEEEHLNHFRGQQMQDTIETDLVVKTVDSKDVLFHLPPFYLPFLFKWSGYQTSAKTRCHKRKRCQAIHSLKLSRTHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASPEDRPPHTTHIVFVVHGIGQKMDQGRIIKNTGMLREGVRKMEDKHFSKHKDE--HVEFLPVEWRSKLTLDGDTVESITPDKVRGLRDLLNSSAMDIMYYNSPLYRDEITKGLTQELNRLYSLFCSRNPEFEEKGGKVSIVAHSLGCVITYDIITGWDPVRFCLQEHRAVEEETDLRWMSYEEKQLLQQLKNTRSRLLDLENQLVALE------------------ASRPSVPPALKF--------KVENFFCMGSPLAVFLALRGIRPGISCHQDHILPTSICSRLFNVFHPTDPVAYRLEPLILKHYSNIAPVQI 694
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: sec23ip (SEC23 interacting protein [Source:NCBI gene;Acc:101155540]) HSP 1 Score: 114.39 bits (285), Expect = 1.226e-25 Identity = 103/361 (28.53%), Postives = 165/361 (45.71%), Query Frame = 2
Query: 137 ETRWFY-KSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADV--VKRICVPIYWTDSNDNFDIYRGTWFI-ADT---FEPLIENLADAIESQFMMNFLSLQYS-----CLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSV--------LKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDS----ITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDII 1147
+ WFY K VE K+++ FS +DSL+LE + ++++ E +IV++D DV R+ +YW + + ++ R TWF DT F P E+ +D +E+++ + Q+ + N KVI + S+ +W Q D + +K+ +H + D + I HL F+VHGIG + R + ++SV KK H S R+EFLP++W T L+ D +D IT LR N T++D+L+Y+S Y I V E NR+Y++F RNP + G VS+ HSLGS+I +D++
Sbjct: 253 QPHWFYCKKVEL--KSVWLPFSIFDSLQLEETY---------NSVQPDPESVIVRTDGGRYDVQLYDRLRTAVYWEE--EPTEVRRCTWFYKGDTDSRFIPYSEDFSDKLEAEYKRAVSTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSMPDQWGTTQ-----DGETRPRVVKRGIDDDHDEVP-------------DGELHKIDHLVFMVHGIGP-VCDLRFRSMIECVDDFRSVSLKLLHSHFKKSLDEHAVS--RVEFLPVQWHTALHGDATGVDRRIKRITLPSTGRLRHFTNETLLDVLFYNSPTYCQTILDTVALEMNRLYALFLKRNPDYR---GGVSVAGHSLGSLILFDLL 576 HSP 2 Score: 64.6994 bits (156), Expect = 3.383e-10 Identity = 33/68 (48.53%), Postives = 47/68 (69.12%), Query Frame = 2
Query: 1403 NFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHI 1606
NFF LGSP+ +FL +RGL +D++ LP C+ FNIYH DPVAYR+EP+++ + L++ PV I
Sbjct: 744 NFFALGSPIGMFLTVRGLE---KIDESYQLP--TCRGFFNIYHPLDPVAYRIEPMIVPD-LELKPVLI 805
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000014209.1 (SMESG000014209.1) HSP 1 Score: 1450.26 bits (3753), Expect = 0.000e+0 Identity = 705/705 (100.00%), Postives = 705/705 (100.00%), Query Frame = 2
Query: 2 MDRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL 2116
MDRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL
Sbjct: 30 MDRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL 734
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000014209.1 (SMESG000014209.1) HSP 1 Score: 1448.34 bits (3748), Expect = 0.000e+0 Identity = 704/704 (100.00%), Postives = 704/704 (100.00%), Query Frame = 2
Query: 5 DRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL 2116
DRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL
Sbjct: 12 DRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWTDSNDNFDIYRGTWFIADTFEPLIENLADAIESQFMMNFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEIGNRRNPKKPNDLKIPDIKVISATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSIMPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTNNIPPGNNPREMNNENLMLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQMIFEL 715
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000016266.1 (SMESG000016266.1) HSP 1 Score: 396.741 bits (1018), Expect = 1.489e-125 Identity = 224/548 (40.88%), Postives = 327/548 (59.67%), Query Frame = 2
Query: 41 DTDNLSSFFKSQESLEGNPSIGENKIE----ILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWT---DSNDNFDIYRGTWFIADTFEPL-IENLADAIESQFMM----NFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNI-NLNNSLSFDYQFKSSDELLLKNRKLTDL---QNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI 1633
+ N+SS F + LE S E+K L+PE+ RWFYK E ++ F GYDSLRLETKFREL+ S+ ES EKI+V+ DL+E DV+ RI PIYW D ++F I RGTWF +++PL E +A+ IE + + N S +SQK + ++ Y I+WY+ ++Y ++ + +L ++ K G K+ RGYK + ++DK DI+HL FV+HGIGQ++ G I Q K++ + V KK++ + R+EFLP+EWR +L LDG +D ITP KGLR + N+T +DILYYSS +Y+ E+ ++ E NR+YSMFC+R+PYFE KGGKVS IAHSLG+V+ YDI+ +W I +L D + K+S E ++ +DL + + + E ++ + +T ++ NFPSNF G LWK + ++N F +GSPL VFL LRGL P+N+ + ILP+ +C+R+FNI+H +DPV YRLEPL+ + Y I+PV I L ++I
Sbjct: 38 NASNVSSVFNNSVRLESQNSYSESKTSNILLPLYPEKIRWFYK-----ENKLWIPFCGYDSLRLETKFRELTNQSVVSS-ESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLN---KVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQ--LFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKI 574
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000016266.1 (SMESG000016266.1) HSP 1 Score: 370.163 bits (949), Expect = 1.080e-115 Identity = 220/548 (40.15%), Postives = 320/548 (58.39%), Query Frame = 2
Query: 41 DTDNLSSFFKSQESLEGNPSIGENKIE----ILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWT---DSNDNFDIYRGTWFIADTFEPL-IENLADAIESQFMM----NFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNI-NLNNSLSFDYQFKSSDELLLKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNF---PSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI 1633
+ N+SS F + LE S E+K L+PE+ RWFYK E ++ F GYDSLRLETKFREL+ S+ ES EKI+V+ DL+E DV+ RI PIYW D ++F I RGTWF +++PL E +A+ IE + + N S +SQK + ++ Y I+WY+ ++Y ++ + +L ++ K G K+ RGYK + ++DK DI+HL FV+HGIGQ++ G I Q K++ + V KK++ + R+EFLP+EWR +L LDG +D ITP KGLR + N+T +DILYYSS +Y+ E+ ++ E NR+YSMFC+R+PYFE KGGKVS IAHSLG+V+ YDI+ +W I +L D + K+S E NR L ++++ +E + H L + +Q N +NF+ ++N F +GSPL VFL LRGL P+N+ + ILP+ +C+R+FNI+H +DPV YRLEPL+ + Y I+PV I L ++I
Sbjct: 38 NASNVSSVFNNSVRLESQNSYSESKTSNILLPLYPEKIRWFYK-----ENKLWIPFCGYDSLRLETKFRELTNQSVVSS-ESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLN---KVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHE----NR--MQLFSDLNVAKEKV-----HHLELLVLTKAEQENTNRGQTNFR----------LENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKI 555
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000068161.1 (SMESG000068161.1) HSP 1 Score: 253.447 bits (646), Expect = 2.683e-73 Identity = 214/754 (28.38%), Postives = 366/754 (48.54%), Query Frame = 2
Query: 101 IGENKIEILHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFK-GKSNLES-STEKIIVKSDLFEADVVKRICVPIYWTDSNDN----FDIYRGTWFIADTFEPL-IENLADAIESQFMMNFLSLQYSCLDSNVSQKNR---KVIH-----------AMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRLAGHINRQCYKLKQSYKSVLKKYYAPHVT-SKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNINLNNSLSFDYQFKSSDELL-LKNRKLTDLQNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRG--LNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEY----------------LQIDPVHIKLLTS---EDEIGNRRNPKKPNDLKIPDIKVI------SATESEVSCFEDEDEENGIPKSIEDHFSRTFRRFSQATSI--MPAVDELQLKFNSLKEYSFLKRFNLFLNILKGKDLKTN---NIPPGNNPREMNNENL------------------------MLSERLDYTLGEENGISSYISLLTSHTSYWEDLNLAKFLIDQM----IFE 2113
+GE E L RWFY+ EK+++ F+GYDSL+LE R ++ +N + + I+V+ +++ ++++R I++ +S+D+ I RGTWF D+ PL E L++AIE Q L L +C D ++ KV H +M ++Y IEW + + ++ ++ Y + K+ + + G KI RGY E ++DK +I HLCFV+ GIG+ N Y+ V K + + SK +I F+P++W+ +L + + ++I+P + GLR I N++ DILYY++ L+ +I ++SE NR+YS+FC N YF GKVS IAHSLGSVI +DI+ +W P NN F+ + E + N K + +NN+ + + F+ + +++ L F ++N F +GSPL +FL RG L+P + Q D++ H+C+R +NI+H +DP+ YR+EPL+ + Y L + P+ +LL + +D + K+ +IP+ + + TE+ + F + E ++ E H S++ R AT+ ++ ++ + +S Y+ +K +L + +G + N N N + +NN N L RLD+ L + + +SY S ++SH SYW D +L+ F++ Q+ IFE
Sbjct: 9 VGECIAEKLKLSLVRWFYR-----EKSVWTAFTGYDSLQLEENHRSINEMDVTNTNFQRLKDDYILVRGNMYMVNLLRRKMFSIFYIESDDDNEEPLTIIRGTWFHNDSHLPLETELLSNAIEDQH----LKLFGACDDKKKKKETNFVGKVAHKLSKQLKLKVFSMDVNDYHIEWGGMNDVFINKPSTKQYVLDKMGLG---RVGNKICRGYHETALMNDKLPNIDHLCFVIEGIGKTYG---NNTIYEKVSDLMKVTDKIISDTSSYSKQKIAFIPVDWQKSLAFNYDIFENISPDNNPGLRMIVNSSSQDILYYTNPLFYSDIIESLKSELNRVYSIFCRHNDYFVKNNGKVSAIAHSLGSVILFDILSNWS-PQQQYNNWKEFEINSGAKAESSSIFNGKSYETKNNVQKFQ---LHLFQQNDSENRLPIHTIFQF--------------QIENLFFIGSPLAIFLAFRGIKLHPNGL--QEDLIKPHICKRFYNIFHPNDPLVYRIEPLINEYYSKIKPVLIQRPNCEGTLPLPPMSHRLLYTPIIDDGTPYKSWDKRFVSSEIPEFYNVEYSDDENMTENLIKSFSNAGLETK--ETYEMHSSKSSMRGKPATNFYYQKNMNIIERRNDSNVVYT-IKAVSLHDSTSRGSNYNENSLTNTGDRNKLQGLNNMNFSKNSVPSKTIKSEIEPQSDLEIHKTLKWRLDFKLPQNHYENSYFSAISSHESYWTDEDLSFFILSQIHKDPIFE 724 The following BLAST results are available for this feature:
BLAST of DDHD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of DDHD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of DDHD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012287 ID=SMED30012287|Name=DDHD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2316bpback to top protein sequence of SMED30012287-orf-1 >SMED30012287-orf-1 ID=SMED30012287-orf-1|Name=SMED30012287-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=706bp MDRRLGSYEIIFSDTDNLSSFFKSQESLEGNPSIGENKIEILHPEETRWFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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