Talin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012271 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 17
Homology
BLAST of Talin vs. Ensembl Human
Match: TLN1 (talin 1 [Source:HGNC Symbol;Acc:HGNC:11845]) HSP 1 Score: 1010.36 bits (2611), Expect = 0.000e+0 Identity = 852/2769 (30.77%), Postives = 1407/2769 (50.81%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMK-TMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQP--IAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASN------YQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVI--QGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLA-QLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS-----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDTVTD----------------NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVT--GVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFI---GQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + T+VYD CR + +RIP+ +FGLF+SD D + WL+ K + YY L GD + ++ + R L IR +D T KT+ VDDSK++ ++++ IC ++GI+NH+EYSL+ EL E ++ + T TL++ KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G K K+ +LK+FLPKEYVK KG ++KI ++ S+ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ + N + + H G + + + R G++ P + + Q + Q + + L+ ++AL I +++ ++AA LD + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N L E R V + ++E +G L++AAK L A +LL +++P + E + L++A VG+AS LL I SD + +D L+ AK +A+ + ++K SVA + T+ + Q +I AA +TS L++ KVVA +I P+ Q+QL + + V +V+ + Q E ++ + + + +++++L QH+ ++ A D L+ +E + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA K+V A K + + E QQ L +AA + + A I+++L + LE A +Q A +A Q + ++Q AA T +AS Q C E +P ++ + P P+AQ L+ A Q +Q +++ +++A P ++D + L+ +N T+LA+L+ Q+A P + + ++ +Q L + + G+L PLPGET+E + +G+S+KA S +L + N NY G+ +A+++ + L + ARG+AAL S + + DV+D +I + G + R + ++ K++ + ++ V +P +++D + L++ + + + ++ P T + + QS A A NQ +L+ S T L + + + L G+++ + P+ ++ Q+ S LK +S +S+ LL K L + ++ L AA V+DSIN L++ C P Q+ C+++ R+LE ++ L E P PIN+ SY C+ SV E S+ L M I K G+ +F AI S + ++ QA Y +G+ N+ V P + A M+ C S+ ++ AT + S++C + +++P + + + + K VA +T NL+KTI + + + EN +A +L V+ L+ A +NP +I Q GR A I ++ M+E + L++ A AL + + P+ + +T + +L ++ APGQ E L LR+LD+A++ S + + S +++++ +M +++++ + I P+ N + +++ LG V + Y P++ ++ A + L H + +++ TKT+ E+ L ++ + + L E V + +DL ++ AS G + M+ SI ++ +L E P + T + ++ K I TV + N L D RL E+ A E+ +I S + + ++L H +LVT G +Q S A Y +KE I +V +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+F +N E + + A +E I K K LV D + +V + G QE LA A ++V +L VK LG + + E Q +L+NAV+DVA AL D + TK D + LK+S + MV +V L+K+VK++ED +GTRALE + E +R+E + P K + E+ + MTK + +A+ KA+AA + +QED++ AN+ R+AI D++ KE P E AP V ++ + +G+ +++ +++ ++ K + K Q+T S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + ++ + MV + +I AQ +++ KERELE R K IRQ
Sbjct: 1 MVALSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGD---TMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKG-ERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQY----------NRVGKVEH----GSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGD---PAETDYTAVGCAVTTISSN---LTEMSRGVKLLAALLEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAE-----------------PRQNLLQAAGNVGQASGELLQQIGE-----SDTDPHFQDALMQLAKAVASAAA--ALVLKAKSVA-QRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLL-RGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGES------------DLENSRKLLSAAKILADATAKMVEAAKGAAAHPD-SEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVAEQ----IPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSV----VQNLEKDLQEVKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYA--------GI------AARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQR---LAQVAKAVTQA---LNRCVSCLPGQRDVD---NALRAVGDASKRLLSDSLP-----PSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLK---SQLAAAARAVTDSINQLITMCTQQAP-GQKECDNALRELETVRE--LLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLV-EPTQFARANQAIQMA--CQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFA-----SNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPR-EGISQEALHT---QMLTAVQEISHLIEPLAN--AARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMA-LLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYG--RL-ASEAKPAAVAAENEEIGSH-----IKHRVQELGHGCAALVTKAGALQCSPSDA--------------------------YTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMF-----ATAGTLNREGTE----TFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVK------------LGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGD-DPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPA----------------------------KTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLR--------ACKEAAYHP-----EVAPDV--------------RLRALHYGRECANGYLELLDHVLLTLQ--KPSPELKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPRAK-PKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAL---DDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEEQENETVV--VKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2527
BLAST of Talin vs. Ensembl Human
Match: TLN2 (talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]) HSP 1 Score: 974.156 bits (2517), Expect = 0.000e+0 Identity = 835/2763 (30.22%), Postives = 1420/2763 (51.39%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG-QGNVNV-QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL+ + + YY L + + +L +K + R IR +D + KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E+A + G Q Q + G K K +LKEFLPKEY+K +G +K+I +++ S+ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F N H G + + + R GS+ P S Q V V Q + + L+ ++ALM I ++ ++ A +DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + D+E +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N ++ Q T S + +Q+ +++ +++ L QH + + +P+ + +E + +++G++ EMV QA++LA+A ++L + + S + + +D + ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ AA + + A+ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + +L PLPGET+E + +GS+SKA +L N + + G+ +A+E ++++ L + ARG+AA + + + + DV++ +I+ + + +A A L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L++ C P Q+ C+++ R+LE +K L + P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L M++ ++ +++ V +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+F +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D + TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ +DV +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ + + P VSD R + + G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ P
Sbjct: 5 SLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD-ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF----------NRTGKAEH----GSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---ADTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMSLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAAT-TDSELLKQVSAAASVVSQALHDLLQH--VRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKAVADHI-PQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAVESQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGESSKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATAPLIEAVENLTAFA-----SNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVT--AQEMMTKSVTNPEELGGLA-----------SQMTSDYGHL--AFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMF-----ATAGTLNAENSE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALSDLISATKGAASKPVD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTVFQS-----KDV-----------------------PEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQ-----------------ASFHPDVSDEVR----------TRALRFGTECTLGYLDLLEHV--LVILQKPTPEFKQQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLP 2534
BLAST of Talin vs. Ensembl Human
Match: TLN2 (talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]) HSP 1 Score: 454.136 bits (1167), Expect = 1.315e-130 Identity = 479/1703 (28.13%), Postives = 814/1703 (47.80%), Query Frame = 3
Query: 3201 LIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALV----KEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
L+ E L KS++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + +L PLPGET+E + +GS+SKA +L N + + G+ +A+E ++++ L + ARG+AA + + + + DV++ +I+ + + +A A L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L++ C P Q+ C+++ R+LE +K L + P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L M++ ++ +++ V +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+F +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D + TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ +DV +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ + + P VSD R + + G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV K A D D + + V + +I AQ +++ KERELE R K IRQ
Sbjct: 20 LLIETENLRKSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAVESQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGESSKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATAPLIEAVENLTAFA-----SNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVTA--QEMMTKSVTNPEELGGLA-----------SQMTSDYGHL--AFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMF-----ATAGTLNAENSE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALSDLISATKGAASKPVD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTVFQS-----KDV-----------------------PEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQ-----------------ASFHPDVSDEVR----------TRALRFGTECTLGYLDLLEHV--LVILQKPTPEFKQQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQ 1552
BLAST of Talin vs. Ensembl Human
Match: TLN2 (talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]) HSP 1 Score: 419.083 bits (1076), Expect = 1.202e-119 Identity = 440/1574 (27.95%), Postives = 755/1574 (47.97%), Query Frame = 3
Query: 3633 SAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQ---------------AAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+A+E ++++ L + ARG+AA + + + + DV++ +I+ + + +A A L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L++ C P Q+ C+++ R+LE +K L + P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L M++ ++ +++ V +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+FA +G+ +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D + TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ +DV +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ + + P VSD R + + G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQ AAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ
Sbjct: 36 AARETAQALKTLAQAARGVAASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGESSKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATAPLIEAVENLTAFA-----SNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVTA--QEMMTKSVTNPEELGGLA-----------SQMTSDYGHL--AFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGT-----LNAENSE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALSDLISATKGAASKPVD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTVFQS-----KDV-----------------------PEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQ-----------------ASFHPDVSDEVR----------TRALRFGTECTLGYLDLLEHV--LVILQKPTPEFKQQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQVMVTDAGGKILLLERAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQ 1456
BLAST of Talin vs. Ensembl Human
Match: HIP1 (huntingtin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:4913]) HSP 1 Score: 83.5741 bits (205), Expect = 4.694e-15 Identity = 69/236 (29.24%), Postives = 114/236 (48.31%), Query Frame = 3
Query: 7524 IAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALV------KEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGH 8213
+ + E+ ++ IETA +I + KS DTG + + +I+ C S++ A L+ + Q+E+V GR S ++W+ GLISA++ V + D+A VVQG+ + L+ S ++AA TA L+ A +VK+D DS +LQ A V +AT +V K E D D S + ++ R + +Q ++ E EL+ R K +R+ H
Sbjct: 782 LVDKEMAATSAAIETATARIEEMLS-KSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFS--------SMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKH 1008
BLAST of Talin vs. Ensembl Celegans
Match: tln-1 (TaLiN [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUD9]) HSP 1 Score: 467.233 bits (1201), Expect = 2.595e-140 Identity = 340/1050 (32.38%), Postives = 543/1050 (51.71%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTI--SLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLI-----------------------YELDENERMKTMTLKRGKTQI------RDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGR---VGSAQPIAIRNDSKIGQGNVNVQ----PQKFQIRDLSQ-PKRALMIRIGDNLKILKAATEDLDK--HIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQ-----LDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQT------LENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAK 3050
M L + + K I +++ + T++YD + L + ++ E+G+F D + ++ W+DN + +Y + +K+ + +K ++R L +R +D KT+ VD+S+ +++L++ +CNK+GISN+EEYSL+ + L E E ++ + RG I ++ KLE++++KL TD+EL WL H KTLR+ GI E++ L+LRRKYFFSD NVD+RDP+QLNLLYVQ ++ I+ G HPV E A QLA +Q + G+ DK K H + ++ LPKEY K K +KK++A Y++LSG S+ D K Y LCR LKTYG+TFF+VKEK+ KNKLVPRL+G++KE VMRVDE +K++++ WPL VRR+ +A FSLDFGDY D Y +QTT+GEKIAQLI GY+DII+KK++ +D+ + +E + M+E+ VAP+KA +++H I AT G + RG + G+ + AQ A+ G + Q Q+ + +D+ Q P+RAL+ I ++ ++ A +L+ I++ + +D S + ++ + K V L +M AT ++ +E D R+ AIATIG N + N+R + E G+L++A K L AF LN ++N E A N+ A VGE S+ L++++ + + L+ AK +A + +V K S E Q Q +I +A ATS L++ A+VVA +I+ QQQL +A +V SV+N++ + +YQQ + E + ++D L +H + T ++ + + L + R+ G S ++ +A+ + L + + A Q P++ R+R L DA K+ HAT + +EQ +E + L AA + V + T E Q + + LE A +QTA A Q + ++ A K
Sbjct: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAK-LIREKFAMHDVNANEYGIFRLDENPSKSLWMDNGRTFEHYLVRNKDEIE-YKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKIGISNYEEYSLVRDDILMQNGGGGGGGGGQNGGSTWNLKEKE-SRSKSSDRGGGGIYGTMRKKNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPK-FHLDGRDVLPKEYAKNKENEKKVVAMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIG-------SGQHATDGLVAVRGVLRTPQGGQGYGINGAQYGAV-------SGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGAATAQVVQWTAVEEYDD------RVGTAIATIGSNLPDVSRNVRDLGAFM-----EHRERGDLLDATKKLCGAFGKFLN----------------TVNPETEARRNEVFRTA-GHVGETSQHLINVMEAPNEGQQKFD----ERLVQSAKNVATSTAQLVLCAKTISAECDEPQ---VQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLH------DAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAH-QRPEH------------RER--------LLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGQVTNETTQEQQEQHIMQRLEQAAKQTAYDATQTISAANSAKK 970
BLAST of Talin vs. Ensembl Celegans
Match: tln-1 (TaLiN [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUD9]) HSP 1 Score: 491.115 bits (1263), Expect = 1.384e-139 Identity = 370/1157 (31.98%), Postives = 594/1157 (51.34%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTI--SLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLI-----------------------YELDENERMKTMTLKRGKTQI------RDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG--QGNVNVQ----PQKFQIRDLSQ-PKRALMIRIGDNLKILKAATEDL--DKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQ-----LDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQT------LENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQ--ICSEAQEMTEIVLPEVILACTKIRENPIDPN-------AQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQA 3347
M L + + K I +++ + T++YD + L + ++ E+G+F D + ++ W+DN + +Y + +K+ + +K ++R L +R +D KT+ VD+S+ +++L++ +CNK+GISN+EEYSL+ + L E E ++ + RG I ++ KLE++++KL TD+EL WL H KTLR+ GI E++ L+LRRKYFFSD NVD+RDP+QLNLLYVQ ++ I+ G HPV E A QLA +Q + G+ DK K H + ++ LPKEY K K +KK++A Y++LSG S+ D K Y LCR LKTYG+TFF+VKEK+ KNKLVPRL+G++KE VMRVDE +K++++ WPL VRR+ +A FSLDFGDY D Y +QTT+GEKIAQLI GY+DII+KK++ +D+ + +E + M+E+ VAP+KA +++H I AT G + R GV+ + G I N ++ G G + Q Q+ + +D+ Q P+RAL+ I ++ ++ A +L + I++ + +D S + ++ + K V L +M AT ++ +E D R+ AIATIG N + N+R + E G+L++A K L AF LN ++N E A N+ A VGE S+ L++++ + + L+ AK +A + +V K S E Q Q +I +A ATS L++ A+VVA +I+ QQQL +A +V SV+N++ + +YQQ + E + ++D L +H + T ++ + + L + R+ G S ++ +A+ + L + + A Q P++ R+R L DA K+ HAT + +EQ +E + L AA + V + T E Q + + LE A +QTA A Q + ++ A + +Y+ + E+ + T LP +I T IRE+ N AQ+ L+ K+++ +L +++ P V D + S+L+ S TSLADL+ V A
Sbjct: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAK-LIREKFAMHDVNANEYGIFRLDENPSKSLWMDNGRTFEHYLVRNKDEIE-YKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKIGISNYEEYSLVRDDILMQNGGGGGGGGGQNGGSTWNLKEKES-RSKSSDRGGGGIYGTMRKKNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPK-FHLDGRDVLPKEYAKNKENEKKVVAMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIG-------SGQHATDGLVAVR---GVLRTPQGGQGYGI---NGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGAATAQVVQWTAVEEYDD------RVGTAIATIGSNLPDVSRNVRDLGAFM-----EHRERGDLLDATKKLCGAFGKFLN----------------TVNPETEARRNEVFRTA-GHVGETSQHLINVMEAPNEGQQKFD----ERLVQSAKNVATSTAQLVLCAKTISAECDEPQ---VQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLH------DAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAH-QRPEH------------RER--------LLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGQVTNETTQEQQEQHIMQRLEQAAKQTAYDATQTISAANSAKDVIESRSYKENLVYESTQ-TAGHLPNLI---TSIRESQKVDNTPGEKFKAQSRLIRDSYKVLETSVRLFETARTAVPMVSDSHLASSLDQSANRLGTSLADLRTSVNDA 1074 HSP 2 Score: 311.997 bits (798), Expect = 1.267e-84 Identity = 347/1282 (27.07%), Postives = 595/1282 (46.41%), Query Frame = 3
Query: 4392 QQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKS---RASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENV----SSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARL-TETNNVAPLDA-ASAHTLIFQSIKGITDTVTD-NSLNK-DISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGE--EYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEH---RDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNK 8189
Q+ C+++ R+++A+ + + ++P+N+ Y +QSV + S L M + K D+ FC++++ + + + +S + + Y +G+ S SS ++DS SV S N S + ++ EL +DI S ++SS+ QL + + +P+ + L+ VA T +L+ R E+ + A E + QL A P +I+ +G AQ I Q+S EM++ S +++ A + + Q +N + + RL N + +APGQ E L + ++R+ MD ++ K A + + +Q++Q QL++ + + N + E L + V + +++++ A + S + E+ + KTV+EA LAM+ N NV LK D+ + I ++S G ++ M+ +I S A ++ P + A A T + ++ I T + +LN D+ L E R+ A + Q AD+ K V L T I+ ++ ED + I+ G V R+ ++ L S SRGTQ CI AAN+V+ ++ DLDT I+F +NS +D+ P+ KE I K K+LV D + +V QE LA+A NAVR L AVK+ A+++ S S Q L+++AVRDVA AL TK N + + + +LK + + MV +V L+K+V ++E+ +GTRA+E +++A+ E + E+ + EG + +++ +++ + + V+ + A Q+ +E+I+ AN+ R A+ L+ +R TI + + P R V D R +VK L+ ++ + V + ES ++ + AS+ ++ ++ + ++ T L + S A AENELL AAS IE A+ K+A L+PR+ ++++T E E FD II++ I+ A L++ AS +Q+EL QGR QWS GLISAAR+V A+ L D+A +++G+ +RLISA+KQV++ TA LL+AC V++D DS+ N+RLQAAG AV+ A E LV+ A + RD ++ +I + +VN + V+ AQ +++ KEREL R+K
Sbjct: 1375 QRECDAALRRIQAVYH--VTQHANVPLNDNGYFASLQSVSDGSRRLGEAMTGMARHAKGNDTEGFCTSVRDSADALCSLAESASHSAYLVGI-----SHPASSPGRAALIDSSEVARSVESINA-SCQRVESRQLNREELMSDISSITKQSSSLAQLCRIASEKTQNPNVKKHLVGCAMGVASKTSSLVTAFKDLDRMPDAESRCTSSASE-LRQVALQLLHFAD-KPDFAAIQGSISTEGHSAQQPILQSSREMLDSSAQMIQTAKSWASAPQDEATWQRMAVNSRQVSDSIMRLVNAIHEAAPGQMELEAAIGRLSALSGQIERSAMDCYASGNVQKHGANAERQL---LQQVQHIASQLEDKVDDLHNAAVEHG--ERLPKVVQLHCQMVEDLADAACCAAGMTVDSNQQTELFDKCKTVVEAELAMMVASRESGGNPNAVHAHANVKDAAGQLKHAIGDMRQTIAKVSSEQGAVQGMVDTISSSIAHTDVAVSSAHPGSSFADAQTRMTAYLEDIRRTAIEMPTLNTTDLGAASLNLSEKY-RLVAGDVRQAAGMLPEADIGQRLKLAVQ---KLGTSCIETVTVAGGKRAHPED--------------ERIQRQLSSQAGTVVERVEQVLAALHSASRGTQACINAANTVSGIIGDLDTTIMF-----ATSGSLNSSDDRKFPSH----KEAIVKTAKALVEDTKALVAGAASNQEQLAVAAQNAVRTIVNLSDAVKTGAVSLSSENS------------ETQVLVIHAVRDVAAALTSLIQATK-NASGLSLQHPAMGHLKDAAKVMVSNVARLLKTVATVEEKNQQGTRAVEAAVDAIGFEMKQFEH-----------DLNEGAAIPTDFRPEHLQQTAEHVSEITKRVM----------QGADAPQS--EEEIIGVANLSRSAVRSLLAVVR-TIS---NDADTAPQRY------AVLDSGRDVANNVK--------------SLLVSLHTQM---VRNPGQEESRRLLLE-ASKGVSSALSHLVGLCNEM--TGLPHNHEMESAAAQAENELLGAASSIEAASAKLAELRPRQIVQENTQEIVETEFDDNIIISAKGILHAVHTLMRSASNAQRELAMQGRAAAGGT----GTYQWSEGLISAARVVVASVHKLCDAANTLMKGQTTEERLISAAKQVSSSTAQLLVACNVRADPDSQANRRLQAAGQAVRNAAERLVQSAQQEMIARDDRNIAI-------SDRLVNGIAQVMDAQEEVLRKERELGEARHK 2537
BLAST of Talin vs. Ensembl Celegans
Match: tln-1 (TaLiN [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUD9]) HSP 1 Score: 308.916 bits (790), Expect = 1.944e-84 Identity = 346/1279 (27.05%), Postives = 591/1279 (46.21%), Query Frame = 3
Query: 4392 QQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKS---RASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENV----SSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARL-TETNNVAPLDA-ASAHTLIFQSIKGITDTVTD-NSLNK-DISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGE--EYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNK 8189
Q+ C+++ R+++A+ + + ++P+N+ Y +QSV + S L M + K D+ FC++++ + + + +S + + Y +G+ S SS ++DS SV S N S + ++ EL +DI S ++SS+ QL + + +P+ + L+ VA T +L+ R E+ + A E + QL A P +I+ +G AQ I Q+S EM++ S +++ A + + Q +N + + RL N + +APGQ E L + ++R+ MD ++ K A + + +Q++Q QL++ + + N + E L + V + +++++ A + S + E+ + KTV+EA LAM+ N NV LK D+ + I ++S G ++ M+ +I S A ++ P + A A T + ++ I T + +LN D+ L E R+ A + Q AD+ K V L T I+ ++ ED + I+ G V R+ ++ L S SRGTQ CI AAN+V+ ++ DLDT I+F +NS +D+ P+ KE I K K+LV D + +V QE LA+A NAVR L AVK+ A+++ S S Q L+++AVRDVA AL TK N + + + +LK + + MV +V L+K+V ++E+ +GTRA+E +++A+ E + E+ + EG + +++ +++ + + V+ + A Q+ +E+I+ AN+ R A+ L+ +R TI + + P R V D R +VK L+ ++ + V + ES ++ + AS+ ++ ++ + ++ T L + S A AENELL AAS IE A+ K+A L+PR+ ++++T E E FD II++ I+ A L++ AS +Q+EL QGR QWS GLISAAR+V A+ L D+A +++G+ +RLISA+KQV++ TA LL+AC V++D DS+ N+RLQAAG AV+ A E LV+ A + +D D +VN + V+ AQ +++ KEREL R+K
Sbjct: 333 QRECDAALRRIQAVYH--VTQHANVPLNDNGYFASLQSVSDGSRRLGEAMTGMARHAKGNDTEGFCTSVRDSADALCSLAESASHSAYLVGI-----SHPASSPGRAALIDSSEVARSVESINA-SCQRVESRQLNREELMSDISSITKQSSSLAQLCRIASEKTQNPNVKKHLVGCAMGVASKTSSLVTAFKDLDRMPDAESRCTSSASE-LRQVALQLLHFAD-KPDFAAIQGSISTEGHSAQQPILQSSREMLDSSAQMIQTAKSWASAPQDEATWQRMAVNSRQVSDSIMRLVNAIHEAAPGQMELEAAIGRLSALSGQIERSAMDCYASGNVQKHGANAERQL---LQQVQHIASQLEDKVDDLHNAAVEHG--ERLPKVVQLHCQMVEDLADAACCAAGMTVDSNQQTELFDKCKTVVEAELAMMVASRESGGNPNAVHAHANVKDAAGQLKHAIGDMRQTIAKVSSEQGAVQGMVDTISSSIAHTDVAVSSAHPGSSFADAQTRMTAYLEDIRRTAIEMPTLNTTDLGAASLNLSEKY-RLVAGDVRQAAGMLPEADIGQRLKLAVQ---KLGTSCIETVTVAGGKRAHPED--------------ERIQRQLSSQAGTVVERVEQVLAALHSASRGTQACINAANTVSGIIGDLDTTIMF-----ATSGSLNSSDDRKFPSH----KEAIVKTAKALVEDTKALVAGAASNQEQLAVAAQNAVRTIVNLSDAVKTGAVSLSSENS------------ETQVLVIHAVRDVAAALTSLIQATK-NASGLSLQHPAMGHLKDAAKVMVSNVARLLKTVATVEEKNQQGTRAVEAAVDAIGFEMKQFEH-----------DLNEGAAIPTDFRPEHLQQTAEHVSEITKRVM----------QGADAPQS--EEEIIGVANLSRSAVRSLLAVVR-TIS---NDADTAPQRY------AVLDSGRDVANNVK--------------SLLVSLHTQM---VRNPGQEESRRLLLE-ASKGVSSALSHLVGLCNEM--TGLPHNHEMESAAAQAENELLGAASSIEAASAKLAELRPRQIVQENTQEIVETEFDDNIIISAKGILHAVHTLMRSASNAQRELAMQGRAAAGGT----GTYQWSEGLISAARVVVASVHKLCDAANTLMKGQTTEERLISAAKQVSSSTAQLLVACNVRADPDSQANRRLQAAGQAVRNAAERLVQSAQQEMIARDDRNIAISD----RLVNGIAQVMDAQEEVLRKERELGEARHK 1495
BLAST of Talin vs. Ensembl Celegans
Match: tln-1 (TaLiN [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUD9]) HSP 1 Score: 309.301 bits (791), Expect = 6.606e-84 Identity = 347/1282 (27.07%), Postives = 595/1282 (46.41%), Query Frame = 3
Query: 4392 QQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKS---RASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENV----SSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARL-TETNNVAPLDA-ASAHTLIFQSIKGITDTVTD-NSLNK-DISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGE--EYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEH---RDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNK 8189
Q+ C+++ R+++A+ + + ++P+N+ Y +QSV + S L M + K D+ FC++++ + + + +S + + Y +G+ S SS ++DS SV S N S + ++ EL +DI S ++SS+ QL + + +P+ + L+ VA T +L+ R E+ + A E + QL A P +I+ +G AQ I Q+S EM++ S +++ A + + Q +N + + RL N + +APGQ E L + ++R+ MD ++ K A + + +Q++Q QL++ + + N + E L + V + +++++ A + S + E+ + KTV+EA LAM+ N NV LK D+ + I ++S G ++ M+ +I S A ++ P + A A T + ++ I T + +LN D+ L E R+ A + Q AD+ K V L T I+ ++ ED + I+ G V R+ ++ L S SRGTQ CI AAN+V+ ++ DLDT I+F +NS +D+ P+ KE I K K+LV D + +V QE LA+A NAVR L AVK+ A+++ S S Q L+++AVRDVA AL TK N + + + +LK + + MV +V L+K+V ++E+ +GTRA+E +++A+ E + E+ + EG + +++ +++ + + V+ + A Q+ +E+I+ AN+ R A+ L+ +R TI + + P R V D R +VK L+ ++ + V + ES ++ + AS+ ++ ++ + ++ T L + S A AENELL AAS IE A+ K+A L+PR+ ++++T E E FD II++ I+ A L++ AS +Q+EL QGR QWS GLISAAR+V A+ L D+A +++G+ +RLISA+KQV++ TA LL+AC V++D DS+ N+RLQAAG AV+ A E LV+ A + RD ++ +I + +VN + V+ AQ +++ KEREL R+K
Sbjct: 1010 QRECDAALRRIQAVYH--VTQHANVPLNDNGYFASLQSVSDGSRRLGEAMTGMARHAKGNDTEGFCTSVRDSADALCSLAESASHSAYLVGI-----SHPASSPGRAALIDSSEVARSVESINA-SCQRVESRQLNREELMSDISSITKQSSSLAQLCRIASEKTQNPNVKKHLVGCAMGVASKTSSLVTAFKDLDRMPDAESRCTSSASE-LRQVALQLLHFAD-KPDFAAIQGSISTEGHSAQQPILQSSREMLDSSAQMIQTAKSWASAPQDEATWQRMAVNSRQVSDSIMRLVNAIHEAAPGQMELEAAIGRLSALSGQIERSAMDCYASGNVQKHGANAERQL---LQQVQHIASQLEDKVDDLHNAAVEHG--ERLPKVVQLHCQMVEDLADAACCAAGMTVDSNQQTELFDKCKTVVEAELAMMVASRESGGNPNAVHAHANVKDAAGQLKHAIGDMRQTIAKVSSEQGAVQGMVDTISSSIAHTDVAVSSAHPGSSFADAQTRMTAYLEDIRRTAIEMPTLNTTDLGAASLNLSEKY-RLVAGDVRQAAGMLPEADIGQRLKLAVQ---KLGTSCIETVTVAGGKRAHPED--------------ERIQRQLSSQAGTVVERVEQVLAALHSASRGTQACINAANTVSGIIGDLDTTIMF-----ATSGSLNSSDDRKFPSH----KEAIVKTAKALVEDTKALVAGAASNQEQLAVAAQNAVRTIVNLSDAVKTGAVSLSSENS------------ETQVLVIHAVRDVAAALTSLIQATK-NASGLSLQHPAMGHLKDAAKVMVSNVARLLKTVATVEEKNQQGTRAVEAAVDAIGFEMKQFEH-----------DLNEGAAIPTDFRPEHLQQTAEHVSEITKRVM----------QGADAPQS--EEEIIGVANLSRSAVRSLLAVVR-TIS---NDADTAPQRY------AVLDSGRDVANNVK--------------SLLVSLHTQM---VRNPGQEESRRLLLE-ASKGVSSALSHLVGLCNEM--TGLPHNHEMESAAAQAENELLGAASSIEAASAKLAELRPRQIVQENTQEIVETEFDDNIIISAKGILHAVHTLMRSASNAQRELAMQGRAAAGGT----GTYQWSEGLISAARVVVASVHKLCDAANTLMKGQTTEERLISAAKQVSSSTAQLLVACNVRADPDSQANRRLQAAGQAVRNAAERLVQSAQQEMIARDDRNIAI-------SDRLVNGIAQVMDAQEEVLRKERELGEARHK 2172 HSP 2 Score: 196.438 bits (498), Expect = 1.388e-49 Identity = 220/788 (27.92%), Postives = 365/788 (46.32%), Query Frame = 3
Query: 1083 MRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG--QGNVNVQ----PQKFQIRDLSQ-PKRALMIRIGDNLKILKAATEDL--DKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQ-----LDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQT------LENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQ--ICSEAQEMTEIVLPEVILACTKIRENPIDPN-------AQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQA 3347
MRVDE +K++++ WPL VRR+ +A FSLDFGDY D Y +QTT+GEKIAQLI GY+DII+KK++ +D+ + +E + M+E+ VAP+KA +++H I AT G + R GV+ + G I N ++ G G + Q Q+ + +D+ Q P+RAL+ I ++ ++ A +L + I++ + +D S + ++ + K V L +M AT ++ +E D R+ AIATIG N + N+R + E G+L++A K L AF LN ++N E A N+ A VGE S+ L++++ + + L+ AK +A + +V K S E Q Q +I +A ATS L++ A+VVA +I+ QQQL +A +V SV+N++ + +YQQ + E + ++D L +H + T ++ + + L + R+ G S ++ +A+ + L + + A Q P++ R+R L DA K+ HAT + +EQ +E + L AA + V + T E Q + + LE A +QTA A Q + ++ A + +Y+ + E+ + T LP +I T IRE+ N AQ+ L+ K+++ +L +++ P V D + S+L+ S TSLADL+ V A
Sbjct: 1 MRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIG-------SGQHATDGLVAVR---GVLRTPQGGQGYGI---NGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGAATAQVVQWTAVEEYDD------RVGTAIATIGSNLPDVSRNVRDLGAFM-----EHRERGDLLDATKKLCGAFGKFLN----------------TVNPETEARRNEVFRTA-GHVGETSQHLINVMEAPNEGQQKFD----ERLVQSAKNVATSTAQLVLCAKTISAECDEPQ---VQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLH------DAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAH-QRPEH------------RER--------LLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGQVTNETTQEQQEQHIMQRLEQAAKQTAYDATQTISAANSAKDVIESRSYKENLVYESTQ-TAGHLPNLI---TSIRESQKVDNTPGEKFKAQSRLIRDSYKVLETSVRLFETARTAVPMVSDSHLASSLDQSANRLGTSLADLRTSVNDA 709
BLAST of Talin vs. Ensembl Celegans
Match: tln-1 (TaLiN [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUD9]) HSP 1 Score: 308.145 bits (788), Expect = 1.106e-83 Identity = 347/1282 (27.07%), Postives = 595/1282 (46.41%), Query Frame = 3
Query: 4392 QQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKS---RASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENV----SSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARL-TETNNVAPLDA-ASAHTLIFQSIKGITDTVTD-NSLNK-DISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGE--EYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEH---RDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNK 8189
Q+ C+++ R+++A+ + + ++P+N+ Y +QSV + S L M + K D+ FC++++ + + + +S + + Y +G+ S SS ++DS SV S N S + ++ EL +DI S ++SS+ QL + + +P+ + L+ VA T +L+ R E+ + A E + QL A P +I+ +G AQ I Q+S EM++ S +++ A + + Q +N + + RL N + +APGQ E L + ++R+ MD ++ K A + + +Q++Q QL++ + + N + E L + V + +++++ A + S + E+ + KTV+EA LAM+ N NV LK D+ + I ++S G ++ M+ +I S A ++ P + A A T + ++ I T + +LN D+ L E R+ A + Q AD+ K V L T I+ ++ ED + I+ G V R+ ++ L S SRGTQ CI AAN+V+ ++ DLDT I+F +NS +D+ P+ KE I K K+LV D + +V QE LA+A NAVR L AVK+ A+++ S S Q L+++AVRDVA AL TK N + + + +LK + + MV +V L+K+V ++E+ +GTRA+E +++A+ E + E+ + EG + +++ +++ + + V+ + A Q+ +E+I+ AN+ R A+ L+ +R TI + + P R V D R +VK L+ ++ + V + ES ++ + AS+ ++ ++ + ++ T L + S A AENELL AAS IE A+ K+A L+PR+ ++++T E E FD II++ I+ A L++ AS +Q+EL QGR QWS GLISAAR+V A+ L D+A +++G+ +RLISA+KQV++ TA LL+AC V++D DS+ N+RLQAAG AV+ A E LV+ A + RD ++ +I + +VN + V+ AQ +++ KEREL R+K
Sbjct: 712 QRECDAALRRIQAVYH--VTQHANVPLNDNGYFASLQSVSDGSRRLGEAMTGMARHAKGNDTEGFCTSVRDSADALCSLAESASHSAYLVGI-----SHPASSPGRAALIDSSEVARSVESINA-SCQRVESRQLNREELMSDISSITKQSSSLAQLCRIASEKTQNPNVKKHLVGCAMGVASKTSSLVTAFKDLDRMPDAESRCTSSASE-LRQVALQLLHFAD-KPDFAAIQGSISTEGHSAQQPILQSSREMLDSSAQMIQTAKSWASAPQDEATWQRMAVNSRQVSDSIMRLVNAIHEAAPGQMELEAAIGRLSALSGQIERSAMDCYASGNVQKHGANAERQL---LQQVQHIASQLEDKVDDLHNAAVEHG--ERLPKVVQLHCQMVEDLADAACCAAGMTVDSNQQTELFDKCKTVVEAELAMMVASRESGGNPNAVHAHANVKDAAGQLKHAIGDMRQTIAKVSSEQGAVQGMVDTISSSIAHTDVAVSSAHPGSSFADAQTRMTAYLEDIRRTAIEMPTLNTTDLGAASLNLSEK-YRLVAGDVRQAAGMLPEADIGQRLKLAVQ---KLGTSCIETVTVAGGKRAHPED--------------ERIQRQLSSQAGTVVERVEQVLAALHSASRGTQACINAANTVSGIIGDLDTTIMF-----ATSGSLNSSDDRKFPSH----KEAIVKTAKALVEDTKALVAGAASNQEQLAVAAQNAVRTIVNLSDAVKTGAVSLSSENS------------ETQVLVIHAVRDVAAALTSLIQATK-NASGLSLQHPAMGHLKDAAKVMVSNVARLLKTVATVEEKNQQGTRAVEAAVDAIGFEMKQFEH-----------DLNEGAAIPTDFRPEHLQQTAEHVSEITKRVM----------QGADAPQS--EEEIIGVANLSRSAVRSLLAVVR-TIS---NDADTAPQRY------AVLDSGRDVANNVK--------------SLLVSLHTQM---VRNPGQEESRRLLLE-ASKGVSSALSHLVGLCNEM--TGLPHNHEMESAAAQAENELLGAASSIEAASAKLAELRPRQIVQENTQEIVETEFDDNIIISAKGILHAVHTLMRSASNAQRELAMQGRAAAGGT----GTYQWSEGLISAARVVVASVHKLCDAANTLMKGQTTEERLISAAKQVSSSTAQLLVACNVRADPDSQANRRLQAAGQAVRNAAERLVQSAQQEMIARDDRNIAI-------SDRLVNGIAQVMDAQEEVLRKERELGEARHK 1874 HSP 2 Score: 63.1586 bits (152), Expect = 3.526e-9 Identity = 96/377 (25.46%), Postives = 167/377 (44.30%), Query Frame = 3
Query: 2289 EAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQ-----LDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQT------LENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQ--ICSEAQEMTEIVLPEVILACTKIRENPIDPN-------AQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQA 3347
+ Q +I +A ATS L++ A+VVA +I+ QQQL +A +V SV+N++ + +YQQ + E + ++D L +H + T ++ + + L + R+ G S ++ +A+ + L + + A Q P++ R+R L DA K+ HAT + +EQ +E + L AA + V + T E Q + + LE A +QTA A Q + ++ A + +Y+ + E+ + T LP +I T IRE+ N AQ+ L+ K+++ +L +++ P V D + S+L+ S TSLADL+ V A
Sbjct: 66 QVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLH------DAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAH-QRPEH------------RER--------LLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGQVTNETTQEQQEQHIMQRLEQAAKQTAYDATQTISAANSAKDVIESRSYKENLVYESTQ-TAGHLPNLI---TSIRESQKVDNTPGEKFKAQSRLIRDSYKVLETSVRLFETARTAVPMVSDSHLASSLDQSANRLGTSLADLRTSVNDA 411
BLAST of Talin vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333108) HSP 1 Score: 925.62 bits (2391), Expect = 0.000e+0 Identity = 821/2776 (29.57%), Postives = 1397/2776 (50.32%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDIC---RDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDE-------NERMKTMTLKRGKTQIRDFD-KLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHL-PNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKF-QIR----DLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQ-NSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSL--------EMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQR-LSKGLEFAGRQTALTADQLVLSSQEAAK-----TTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVA-NIANIEDG--QLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNN-LPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNP-ILD--SLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRA----NMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKAN--EDNQILSQNKMA--------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKS--IKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRL--KPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDV-QDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQG 8210
+LRI + T +++ +T V+D C RD F Q + E+GLF+SD + + WL+ + + YY L +++ L ++ + R L +R +D KT+ VDDS+ +++L++ IC K+GI+NHEEY L+ E +E + + T+TLKR K +D D K+E +++KLKTDDE+NW+ +TLR+ GIDE + +LLRR++FFSDQN+D+RDP+QLNLLYVQ ++AI+DGTHPV ++A + AGIQ + G K K+ +LK+FLP+ YV+TKGI+KKI +++ K S+ D KV+Y + R L TYG+TFFLVKEK+ KNKLVPRL+G++K+ V+R+DE TKE++ +WPLTTVRR+ A+ + F+LDFGDY+++ Y +QTTE E+I QLI GYIDII+KK++ KD+ + +E + M+EE+VAPSKA + H L+ E SLA G + P G+ + + V + Q A +GQ N QP ++R +L++P+RAL+ I +L A E+L + +LG+D S +R+ TLD +K V ++ +M+ AT ++ DE D I A+++ I ++ + +R + + E D +G L+EAA+ L +AF DLL A++P ES E P + L+ A +RVGEA+ +L I+ E+ DL D LL AK +AN + +V K + + + Q A+ +I AA ATS L++ AKVVA ++ ++QL A+A+ V +V+++ ++ + L + +S+ + +H+ ++S H + T+ LS E + IG + EMV A+ L + + A L+QS + Q D+D +R L+ AA+ L DA KLV A ++C + +NQ L +AA + + A +R L + LEF +Q A A Q + ++Q A + T+ + Q C + +P ++ + R P DPNAQ NL+ A ++ I+ Q+ KSS AL+P V D I SA +S L QCV + ++ + R A +E +++ LH +D ++ G+L PLPG+T+E+ + + S+K +L ++ L + +Y + DF RS G+AA T N + + DV+ ++I + +QG A + L ++ ++ + V IP +E+D + + E+ + E ++ ++ +QSE + G+++ S + + L ++ ++ +L +++ + + + L+ VS S LL K + A G + L AA V++SIN L+ A + P Q+ C+++ R +EAL+ L+ + P PIN Y C++ S +L + + K +F ++ ++ S +++S +QA Y +G+ SS P I+D L + ++C ++S +++ T I S +C + ++ N+S+P +N+ + K+VA AT +L++ I + + + E + + +L V+ + Q A + ++ K I+ +GR+AQ + QA +++G +++AA +L + P Q ++ + RL + ++ APGQ + ++ L R LD N S + + ++ S ++N S +L + + PI ++ ++ E LG AV E Y+ P+ + + HS+ + +I+ T++V+E+ + +VQ + + T + L + + + +L + ++ I + G + ++ + +S RLT+ + L+A+ + T + + + SL +++ + + ++ + ++ Q L+Q+ + DV + V D V+ +IQ + GA G K ++ R + +V ++ ++ LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++S+ D S A +E I + K+LV D + +V G Q+ LA A NAV QL AVK A ++GS +Q +++NAV+DVA AL D NCTK+ + + + +LK S MV +V L+K+VK++ED RGTRA+E ++EA+ +E R + + P G N+++ E+L+ +T + A+ KA+AA + Q DI+ AAN+GR+AI++++ R ++ E + SR A A+ + Y +L + N S +M L SRR+A + ++ A LK + D EDP IAENELL AA+ I+ AAKK+A L+PR+ +K + E FD I+ A I+ A++ LV+ A+ +Q+EL+ G++ +P ++ ++ QWS GLISAARLVAAAT +L ++A+ +V+G + LIS +KQVAA TA LL+AC+VKS+ +S+ +RLQAAG+AV ++T+ LV A + + ++ S+ N SMV+ M I A++ ++ KE+ELE R +++R
Sbjct: 5 SLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQP---SEYGLFISDEQNQQGVWLEPGRTLGYYILHNQD-TLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKR-KIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVE--SLAHPGIMRPYDGERSYM-ENEVQTVQYGAF-----VGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASHPDE-----VDTEAISASVSQIAQTIPEVTKEVRLIAALM----ENDTSGDQLLEAARNLCSAFSDLLKAAEP---ESK----------EPP----QHLINAASRVGEATTHVLSTIAEEEVPENRDLH----DMLLALAKAVANTTAALVLRAKNIAASCDDEQ---ARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNE-ASNDPKLKADLLAAARDVSKSLTDMLEHVKLSS-REHANRTSTE-LSPVENV--IIGTDILVSTHDPQEMVRHARTLGQ---------TTAQLIQSIKGEADQQQ---DADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDS-DNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVAD----TIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTD--IPSATQLS-----KGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSSVLHNQRSYAGAAGRDTALALGDFTRS--------------VHGVAA----TTQNPAIIDCADDVVTSSARLIEQAQRTLQG-------ASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMS--------EFPPSSRPYATLQSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEEEVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAK---NLLHAAARGVTESINQLVDASIQSAP-GQKECDNAMRNIEALR--LMLDYPHEPINELGYFDCVEQATGKSRNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHP------SSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQMISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRE--RLVDPLLEAVKAVRQYASSSEFSSVPAK-ISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAVNAQGLSQRRDNNLHGFSGQTMN--------SASELIDKLEPIR--MAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQ-SLLNASYSDTFVDYQTRMVARAKEIASLANEMNAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQK-------------EIARSAR-----EVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLHSDGD----GSFADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQP------------DSQVMVINAVKDVASALGDLINCTKL-ASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATVEAISQEIRAMHSPPPVG----NTQV-----------------------GPEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAISEMLIVCR-SVAWNCAETEELRSRTLE------------------------------AGTAVGESYRDLLSGILH---NCSADDRMHL-SRRVAKCVTDLVAMARLLKGSDWIDPEDPT---VIAENELLGAAASIDAAAKKLASLRPRRQADVKIELDENMKFDEMILEAAKGIMGASAALVRAANAAQRELIDTGKVARRP---LTSSDDGQWSEGLISAARLVAAATHSLVEAAQNLVRGVGTEEMLISTAKQVAASTAQLLIACKVKSNPNSEAGRRLQAAGNAVIKSTDNLVHSAQQGLEAEEEHSLKI-----NTSMVDGMAQEINARSAVLRKEKELEEARQLLKNVRHA 2533
BLAST of Talin vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0305210) HSP 1 Score: 924.85 bits (2389), Expect = 0.000e+0 Identity = 821/2776 (29.57%), Postives = 1397/2776 (50.32%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDIC---RDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDE-------NERMKTMTLKRGKTQIRDFD-KLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHL-PNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKF-QIR----DLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQ-NSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSL--------EMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQR-LSKGLEFAGRQTALTADQLVLSSQEAAK-----TTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVA-NIANIEDG--QLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNN-LPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNP-ILD--SLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDR----ANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKAN--EDNQILSQNKMA--------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKS--IKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRL--KPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDV-QDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQG 8210
+LRI + T +++ +T V+D C RD F Q + E+GLF+SD + + WL+ + + YY L +++ L ++ + R L +R +D KT+ VDDS+ +++L++ IC K+GI+NHEEY L+ E +E + + T+TLKR K +D D K+E +++KLKTDDE+NW+ +TLR+ GIDE + +LLRR++FFSDQN+D+RDP+QLNLLYVQ ++AI+DGTHPV ++A + AGIQ + G K K+ +LK+FLP+ YV+TKGI+KKI +++ K S+ D KV+Y + R L TYG+TFFLVKEK+ KNKLVPRL+G++K+ V+R+DE TKE++ +WPLTTVRR+ A+ + F+LDFGDY+++ Y +QTTE E+I QLI GYIDII+KK++ KD+ + +E + M+EE+VAPSKA + H L+ E SLA G + P G+ + + V + Q A +GQ N QP ++R +L++P+RAL+ I +L A E+L + +LG+D S +R+ TLD +K V ++ +M+ AT ++ DE D I A+++ I ++ + +R + + E D +G L+EAA+ L +AF DLL A++P ES E P + L+ A +RVGEA+ +L I+ E+ DL D LL AK +AN + +V K + + + Q A+ +I AA ATS L++ AKVVA ++ ++QL A+A+ V +V+++ ++ + L + +S+ + +H+ ++S H + T+ LS E + IG + EMV A+ L + + A L+QS + Q D+D +R L+ AA+ L DA KLV A ++C + +NQ L +AA + + A +R L + LEF +Q A A Q + ++Q A + T+ + Q C + +P ++ + R P DPNAQ NL+ A ++ I+ Q+ KSS AL+P V D I SA +S L QCV + ++ + R A +E +++ LH +D ++ G+L PLPG+T+E+ + + S+K +L ++ L + +Y + DF RS G+AA T N + + DV+ ++I + +QG A + L ++ ++ + V IP +E+D + + E+ + E ++ ++ +QSE + G+++ S + + L ++ ++ +L +++ + + + L+ VS S LL K + A G + L AA V++SIN L+ A + P Q+ C+++ R +EAL+ L+ + P PIN Y C++ S +L + + K +F ++ ++ S +++S +QA Y +G+ SS P I+D L + ++C ++S +++ T I S +C + ++ N+S+P +N+ + K+VA AT +L++ I + + + E + + +L V+ + Q A + ++ K I+ +GR+AQ + QA +++G +++AA +L + P Q ++ + RL + ++ APGQ + ++ L R LD N S + + ++ S ++N S +L + + PI ++ ++ E LG AV E Y+ P+ + + HS+ + +I+ T++V+E+ + +VQ + + T + L + + + +L + ++ I + G + ++ + +S RLT+ + L+A+ + T + + + SL +++ + + ++ + ++ Q L+Q+ + DV + V D V+ +IQ + GA G K ++ R + +V ++ ++ LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++S+ D S A +E I + K+LV D + +V G Q+ LA A NAV QL AVK A ++GS +Q +++NAV+DVA AL D NCTK+ + + + +LK S MV +V L+K+VK++ED RGTRA+E ++EA+ +E R + + P G N+++ E+L+ +T + A+ KA+AA + Q DI+ AAN+GR+AI++++ R ++ E + SR A A+ + Y +L + N S +M L SRR+A + ++ A LK + D EDP IAENELL AA+ I+ AAKK+A L+PR+ +K + E FD I+ A I+ A++ LV+ A+ +Q+EL+ G++ +P ++ ++ QWS GLISAARLVAAAT +L ++A+ +V+G + LIS +KQVAA TA LL+AC+VKS+ +S+ +RLQAAG+AV ++T+ LV A + + ++ S+ N SMV+ M I A++ ++ KE+ELE R +++R
Sbjct: 5 SLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQP---SEYGLFISDEQNQQGVWLEPGRTLGYYILHNQD-TLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKR-KIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVE--SLAHPGIMRPYDGERSYM-ENEVQTVQYGAF-----VGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASHPDE-----VDTEAISASVSQIAQTIPEVTKEVRLIAALM----ENDTSGDQLLEAARNLCSAFSDLLKAAEP---ESK----------EPP----QHLINAASRVGEATTHVLSTIAEEEVPENRDLH----DMLLALAKAVANTTAALVLRAKNIAASCDDEQ---ARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNE-ASNDPKLKADLLAAARDVSKSLTDMLEHVKLSS-REHANRTSTE-LSPVENV--IIGTDILVSTHDPQEMVRHARTLGQ---------TTAQLIQSIKGEADQQQ---DADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDS-DNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVAD----TIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTD--IPSATQLS-----KGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSSVLHNQRSYAGAAGRDTALALGDFTRS--------------VHGVAA----TTQNPAIIDCADDVVTSSARLIEQAQRTLQG-------ASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMS--------EFPPSSRPYATLQSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEEEVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAK---NLLHAAARGVTESINQLVDASIQSAP-GQKECDNAMRNIEALR--LMLDYPHEPINELGYFDCVEQATGKSRNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHP------SSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQMISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRE--RLVDPLLEAVKAVRQYASSSEFSSVPAK-ISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAVNAQGLSQRRDNNLHGFSGQTMN--------SASELIDKLEPIR--MAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQ-SLLNASYSDTFVDYQTRMVARAKEIASLANEMNAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQK-------------EIARSAR-----EVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLHSDGD----GSFADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQP------------DSQVMVINAVKDVASALGDLINCTKL-ASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATVEAISQEIRAMHSPPPVG----NTQV-----------------------GPEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAISEMLIVCR-SVAWNCAETEELRSRTLE------------------------------AGTAVGESYRDLLSGILH---NCSADDRMHL-SRRVAKCVTDLVAMARLLKGSDWIDPEDPT---VIAENELLGAAASIDAAAKKLASLRPRRQADVKIELDENMKFDEMILEAAKGIMGASAALVRAANAAQRELIDTGKVARRP---LTSSDDGQWSEGLISAARLVAAATHSLVEAAQNLVRGVGTEEMLISTAKQVAASTAQLLIACKVKSNPNSEAGRRLQAAGNAVIKSTDNLVHSAQQGLEAEEEHSLKI-----NTSMVDGMAQEINARSAVLRKEKELEEARQLLKNVRHA 2533
BLAST of Talin vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333105) HSP 1 Score: 924.85 bits (2389), Expect = 0.000e+0 Identity = 821/2776 (29.57%), Postives = 1397/2776 (50.32%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDIC---RDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDE-------NERMKTMTLKRGKTQIRDFD-KLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHL-PNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKF-QIR----DLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQ-NSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSL--------EMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQR-LSKGLEFAGRQTALTADQLVLSSQEAAK-----TTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVA-NIANIEDG--QLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNN-LPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNP-ILD--SLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDR----ANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKAN--EDNQILSQNKMA--------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKS--IKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRL--KPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDV-QDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQG 8210
+LRI + T +++ +T V+D C RD F Q + E+GLF+SD + + WL+ + + YY L +++ L ++ + R L +R +D KT+ VDDS+ +++L++ IC K+GI+NHEEY L+ E +E + + T+TLKR K +D D K+E +++KLKTDDE+NW+ +TLR+ GIDE + +LLRR++FFSDQN+D+RDP+QLNLLYVQ ++AI+DGTHPV ++A + AGIQ + G K K+ +LK+FLP+ YV+TKGI+KKI +++ K S+ D KV+Y + R L TYG+TFFLVKEK+ KNKLVPRL+G++K+ V+R+DE TKE++ +WPLTTVRR+ A+ + F+LDFGDY+++ Y +QTTE E+I QLI GYIDII+KK++ KD+ + +E + M+EE+VAPSKA + H L+ E SLA G + P G+ + + V + Q A +GQ N QP ++R +L++P+RAL+ I +L A E+L + +LG+D S +R+ TLD +K V ++ +M+ AT ++ DE D I A+++ I ++ + +R + + E D +G L+EAA+ L +AF DLL A++P ES E P + L+ A +RVGEA+ +L I+ E+ DL D LL AK +AN + +V K + + + Q A+ +I AA ATS L++ AKVVA ++ ++QL A+A+ V +V+++ ++ + L + +S+ + +H+ ++S H + T+ LS E + IG + EMV A+ L + + A L+QS + Q D+D +R L+ AA+ L DA KLV A ++C + +NQ L +AA + + A +R L + LEF +Q A A Q + ++Q A + T+ + Q C + +P ++ + R P DPNAQ NL+ A ++ I+ Q+ KSS AL+P V D I SA +S L QCV + ++ + R A +E +++ LH +D ++ G+L PLPG+T+E+ + + S+K +L ++ L + +Y + DF RS G+AA T N + + DV+ ++I + +QG A + L ++ ++ + V IP +E+D + + E+ + E ++ ++ +QSE + G+++ S + + L ++ ++ +L +++ + + + L+ VS S LL K + A G + L AA V++SIN L+ A + P Q+ C+++ R +EAL+ L+ + P PIN Y C++ S +L + + K +F ++ ++ S +++S +QA Y +G+ SS P I+D L + ++C ++S +++ T I S +C + ++ N+S+P +N+ + K+VA AT +L++ I + + + E + + +L V+ + Q A + ++ K I+ +GR+AQ + QA +++G +++AA +L + P Q ++ + RL + ++ APGQ + ++ L R LD N S + + ++ S ++N S +L + + PI ++ ++ E LG AV E Y+ P+ + + HS+ + +I+ T++V+E+ + +VQ + + T + L + + + +L + ++ I + G + ++ + +S RLT+ + L+A+ + T + + + SL +++ + + ++ + ++ Q L+Q+ + DV + V D V+ +IQ + GA G K ++ R + +V ++ ++ LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++S+ D S A +E I + K+LV D + +V G Q+ LA A NAV QL AVK A ++GS +Q +++NAV+DVA AL D NCTK+ + + + +LK S MV +V L+K+VK++ED RGTRA+E ++EA+ +E R + + P G N+++ E+L+ +T + A+ KA+AA + Q DI+ AAN+GR+AI++++ R ++ E + SR A A+ + Y +L + N S +M L SRR+A + ++ A LK + D EDP IAENELL AA+ I+ AAKK+A L+PR+ +K + E FD I+ A I+ A++ LV+ A+ +Q+EL+ G++ +P ++ ++ QWS GLISAARLVAAAT +L ++A+ +V+G + LIS +KQVAA TA LL+AC+VKS+ +S+ +RLQAAG+AV ++T+ LV A + + ++ S+ N SMV+ M I A++ ++ KE+ELE R +++R
Sbjct: 5 SLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQP---SEYGLFISDEQNQQGVWLEPGRTLGYYILHNQD-TLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKR-KIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVE--SLAHPGIMRPYDGERSYM-ENEVQTVQYGAF-----VGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASHPDE-----VDTEAISASVSQIAQTIPEVTKEVRLIAALM----ENDTSGDQLLEAARNLCSAFSDLLKAAEP---ESK----------EPP----QHLINAASRVGEATTHVLSTIAEEEVPENRDLH----DMLLALAKAVANTTAALVLRAKNIAASCDDEQ---ARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNE-ASNDPKLKADLLAAARDVSKSLTDMLEHVKLSS-REHANRTSTE-LSPVENV--IIGTDILVSTHDPQEMVRHARTLGQ---------TTAQLIQSIKGEADQQQ---DADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDS-DNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVAD----TIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTD--IPSATQLS-----KGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSSVLHNQRSYAGAAGRDTALALGDFTRS--------------VHGVAA----TTQNPAIIDCADDVVTSSARLIEQAQRTLQG-------ASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMS--------EFPPSSRPYATLQSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEEEVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAK---NLLHAAARGVTESINQLVDASIQSAP-GQKECDNAMRNIEALR--LMLDYPHEPINELGYFDCVEQATGKSRNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHP------SSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQMISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRE--RLVDPLLEAVKAVRQYASSSEFSSVPAK-ISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAVNAQGLSQRRDNNLHGFSGQTMN--------SASELIDKLEPIR--MAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQ-SLLNASYSDTFVDYQTRMVARAKEIASLANEMNAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQK-------------EIARSAR-----EVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLHSDGD----GSFADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQP------------DSQVMVINAVKDVASALGDLINCTKL-ASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATVEAISQEIRAMHSPPPVG----NTQV-----------------------GPEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAISEMLIVCR-SVAWNCAETEELRSRTLE------------------------------AGTAVGESYRDLLSGILH---NCSADDRMHL-SRRVAKCVTDLVAMARLLKGSDWIDPEDPT---VIAENELLGAAASIDAAAKKLASLRPRRQADVKIELDENMKFDEMILEAAKGIMGASAALVRAANAAQRELIDTGKVARRP---LTSSDDGQWSEGLISAARLVAAATHSLVEAAQNLVRGVGTEEMLISTAKQVAASTAQLLIACKVKSNPNSEAGRRLQAAGNAVIKSTDNLVHSAQQGLEAEEEHSLKI-----NTSMVDGMAQEINARSAVLRKEKELEEARQLLKNVRHA 2533
BLAST of Talin vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333106) HSP 1 Score: 924.85 bits (2389), Expect = 0.000e+0 Identity = 821/2776 (29.57%), Postives = 1397/2776 (50.32%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDIC---RDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDE-------NERMKTMTLKRGKTQIRDFD-KLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHL-PNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKF-QIR----DLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQ-NSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSL--------EMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQR-LSKGLEFAGRQTALTADQLVLSSQEAAK-----TTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVA-NIANIEDG--QLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNN-LPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNP-ILD--SLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDR----ANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKAN--EDNQILSQNKMA--------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKS--IKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRL--KPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDV-QDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQG 8210
+LRI + T +++ +T V+D C RD F Q + E+GLF+SD + + WL+ + + YY L +++ L ++ + R L +R +D KT+ VDDS+ +++L++ IC K+GI+NHEEY L+ E +E + + T+TLKR K +D D K+E +++KLKTDDE+NW+ +TLR+ GIDE + +LLRR++FFSDQN+D+RDP+QLNLLYVQ ++AI+DGTHPV ++A + AGIQ + G K K+ +LK+FLP+ YV+TKGI+KKI +++ K S+ D KV+Y + R L TYG+TFFLVKEK+ KNKLVPRL+G++K+ V+R+DE TKE++ +WPLTTVRR+ A+ + F+LDFGDY+++ Y +QTTE E+I QLI GYIDII+KK++ KD+ + +E + M+EE+VAPSKA + H L+ E SLA G + P G+ + + V + Q A +GQ N QP ++R +L++P+RAL+ I +L A E+L + +LG+D S +R+ TLD +K V ++ +M+ AT ++ DE D I A+++ I ++ + +R + + E D +G L+EAA+ L +AF DLL A++P ES E P + L+ A +RVGEA+ +L I+ E+ DL D LL AK +AN + +V K + + + Q A+ +I AA ATS L++ AKVVA ++ ++QL A+A+ V +V+++ ++ + L + +S+ + +H+ ++S H + T+ LS E + IG + EMV A+ L + + A L+QS + Q D+D +R L+ AA+ L DA KLV A ++C + +NQ L +AA + + A +R L + LEF +Q A A Q + ++Q A + T+ + Q C + +P ++ + R P DPNAQ NL+ A ++ I+ Q+ KSS AL+P V D I SA +S L QCV + ++ + R A +E +++ LH +D ++ G+L PLPG+T+E+ + + S+K +L ++ L + +Y + DF RS G+AA T N + + DV+ ++I + +QG A + L ++ ++ + V IP +E+D + + E+ + E ++ ++ +QSE + G+++ S + + L ++ ++ +L +++ + + + L+ VS S LL K + A G + L AA V++SIN L+ A + P Q+ C+++ R +EAL+ L+ + P PIN Y C++ S +L + + K +F ++ ++ S +++S +QA Y +G+ SS P I+D L + ++C ++S +++ T I S +C + ++ N+S+P +N+ + K+VA AT +L++ I + + + E + + +L V+ + Q A + ++ K I+ +GR+AQ + QA +++G +++AA +L + P Q ++ + RL + ++ APGQ + ++ L R LD N S + + ++ S ++N S +L + + PI ++ ++ E LG AV E Y+ P+ + + HS+ + +I+ T++V+E+ + +VQ + + T + L + + + +L + ++ I + G + ++ + +S RLT+ + L+A+ + T + + + SL +++ + + ++ + ++ Q L+Q+ + DV + V D V+ +IQ + GA G K ++ R + +V ++ ++ LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++S+ D S A +E I + K+LV D + +V G Q+ LA A NAV QL AVK A ++GS +Q +++NAV+DVA AL D NCTK+ + + + +LK S MV +V L+K+VK++ED RGTRA+E ++EA+ +E R + + P G N+++ E+L+ +T + A+ KA+AA + Q DI+ AAN+GR+AI++++ R ++ E + SR A A+ + Y +L + N S +M L SRR+A + ++ A LK + D EDP IAENELL AA+ I+ AAKK+A L+PR+ +K + E FD I+ A I+ A++ LV+ A+ +Q+EL+ G++ +P ++ ++ QWS GLISAARLVAAAT +L ++A+ +V+G + LIS +KQVAA TA LL+AC+VKS+ +S+ +RLQAAG+AV ++T+ LV A + + ++ S+ N SMV+ M I A++ ++ KE+ELE R +++R
Sbjct: 5 SLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQP---SEYGLFISDEQNQQGVWLEPGRTLGYYILHNQD-TLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKR-KIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVE--SLAHPGIMRPYDGERSYM-ENEVQTVQYGAF-----VGQVNHAHQPPTTKEVRISSVNLTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASHPDE-----VDTEAISASVSQIAQTIPEVTKEVRLIAALM----ENDTSGDQLLEAARNLCSAFSDLLKAAEP---ESK----------EPP----QHLINAASRVGEATTHVLSTIAEEEVPENRDLH----DMLLALAKAVANTTAALVLRAKNIAASCDDEQ---ARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNE-ASNDPKLKADLLAAARDVSKSLTDMLEHVKLSS-REHANRTSTE-LSPVENV--IIGTDILVSTHDPQEMVRHARTLGQ---------TTAQLIQSIKGEADQQQ---DADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDS-DNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVAD----TIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTD--IPSATQLS-----KGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSSVLHNQRSYAGAAGRDTALALGDFTRS--------------VHGVAA----TTQNPAIIDCADDVVTSSARLIEQAQRTLQG-------ASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMS--------EFPPSSRPYATLQSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEEEVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAK---NLLHAAARGVTESINQLVDASIQSAP-GQKECDNAMRNIEALR--LMLDYPHEPINELGYFDCVEQATGKSRNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHP------SSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQMISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRE--RLVDPLLEAVKAVRQYASSSEFSSVPAK-ISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAVNAQGLSQRRDNNLHGFSGQTMN--------SASELIDKLEPIR--MAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQ-SLLNASYSDTFVDYQTRMVARAKEIASLANEMNAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQK-------------EIARSAR-----EVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLHSDGD----GSFADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQP------------DSQVMVINAVKDVASALGDLINCTKL-ASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATVEAISQEIRAMHSPPPVG----NTQV-----------------------GPEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAISEMLIVCR-SVAWNCAETEELRSRTLE------------------------------AGTAVGESYRDLLSGILH---NCSADDRMHL-SRRVAKCVTDLVAMARLLKGSDWIDPEDPT---VIAENELLGAAASIDAAAKKLASLRPRRQADVKIELDENMKFDEMILEAAKGIMGASAALVRAANAAQRELIDTGKVARRP---LTSSDDGQWSEGLISAARLVAAATHSLVEAAQNLVRGVGTEEMLISTAKQVAASTAQLLIACKVKSNPNSEAGRRLQAAGNAVIKSTDNLVHSAQQGLEAEEEHSLKI-----NTSMVDGMAQEINARSAVLRKEKELEEARQLLKNVRHA 2533
BLAST of Talin vs. Ensembl Fly
Match: rhea (gene:FBgn0260442 transcript:FBtr0333107) HSP 1 Score: 920.228 bits (2377), Expect = 0.000e+0 Identity = 814/2770 (29.39%), Postives = 1388/2770 (50.11%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDIC---RDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDE-------NERMKTMTLKRGKTQIRDFD-KLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQ-NSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSL--------EMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQR-LSKGLEFAGRQTALTADQLVLSSQEAAK-----TTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVA-NIANIEDG--QLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNN-LPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNP-ILD--SLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRA----NMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKAN--EDNQILSQNKMA--------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKS--IKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRL--KPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDV-QDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQG 8210
+LRI + T +++ +T V+D C RD F Q + E+GLF+SD + + WL+ + + YY L +++ L ++ + R L +R +D KT+ VDDS+ +++L++ IC K+GI+NHEEY L+ E +E + + T+TLKR K +D D K+E +++KLKTDDE+NW+ +TLR+ GIDE + +LLRR++FFSDQN+D+RDP+QLNLLYVQ ++AI+DGTHPV ++A + AGIQ + G K K+ +LK+FLP+ YV+TKGI+KKI +++ K S+ D KV+Y + R L TYG+TFFLVKEK+ KNKLVPRL+G++K+ V+R+DE TKE++ +WPLTTVRR+ A+ + F+LDFGDY+++ Y +QTTE E+I QLI GYIDII+KK++ KD+ + +E + M+EE+VAPSKA + H L+ E SLA G + + S P+ + ++ +VN L++P+RAL+ I +L A E+L + +LG+D S +R+ TLD +K V ++ +M+ AT ++ DE D I A+++ I ++ + +R + + E D +G L+EAA+ L +AF DLL A++P ES E P + L+ A +RVGEA+ +L I+ E+ DL D LL AK +AN + +V K + + + Q A+ +I AA ATS L++ AKVVA ++ ++QL A+A+ V +V+++ ++ + L + +S+ + +H+ ++S H + T+ LS E + IG + EMV A+ L + + A L+QS + Q D+D +R L+ AA+ L DA KLV A ++C + +NQ L +AA + + A +R L + LEF +Q A A Q + ++Q A + T+ + Q C + +P ++ + R P DPNAQ NL+ A ++ I+ Q+ KSS AL+P V D I SA +S L QCV + ++ + R A +E +++ LH +D ++ G+L PLPG+T+E+ + + S+K +L ++ L + +Y + DF RS G+AA T N + + DV+ ++I + +QG A + L ++ ++ + V IP +E+D + + E+ + E ++ ++ +QSE + G+++ S + + L ++ ++ +L +++ + + + L+ VS S LL K + A G + L AA V++SIN L+ A + P Q+ C+++ R +EAL+ L+ + P PIN Y C++ S +L + + K +F ++ ++ S +++S +QA Y +G+ SS P I+D L + ++C ++S +++ T I S +C + ++ N+S+P +N+ + K+VA AT +L++ I + + + E + + +L V+ + Q A + ++ K I+ +GR+AQ + QA +++G +++AA +L + P Q ++ + RL + ++ APGQ + ++ L R LD N S + + ++ S ++N S +L + + PI ++ ++ E LG AV E Y+ P+ + + HS+ + +I+ T++V+E+ + +VQ + + T + L + + + +L + ++ I + G + ++ + +S RLT+ + L+A+ + T + + + SL +++ + + ++ + ++ Q L+Q+ + DV + V D V+ +IQ + GA G K ++ R + +V ++ ++ LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++S+ D S A +E I + K+LV D + +V G Q+ LA A NAV QL AVK A ++GS +Q +++NAV+DVA AL D NCTK+ + + + +LK S MV +V L+K+VK++ED RGTRA+E ++EA+ +E R + + P G N+++ E+L+ +T + A+ KA+AA + Q DI+ AAN+GR+AI++++ R ++ E + SR A A+ + Y +L + N S +M L SRR+A + ++ A LK + D EDP IAENELL AA+ I+ AAKK+A L+PR+ +K + E FD I+ A I+ A++ LV+ A+ +Q+EL+ G++ +P ++ ++ QWS GLISAARLVAAAT +L ++A+ +V+G + LIS +KQVAA TA LL+AC+VKS+ +S+ +RLQAAG+AV ++T+ LV A + + ++ S+ N SMV+ M I A++ ++ KE+ELE R +++R
Sbjct: 5 SLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQP---SEYGLFISDEQNQQGVWLEPGRTLGYYILHNQD-TLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKR-KIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVE--SLAHPG----------IMRPYDASGHPMFYKT-KEVRISSVN----------LTEPQRALLGYISAGQDVLIRADEELRTKAPIQELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATAQIITASHPDE-----VDTEAISASVSQIAQTIPEVTKEVRLIAALM----ENDTSGDQLLEAARNLCSAFSDLLKAAEP---ESK----------EPP----QHLINAASRVGEATTHVLSTIAEEEVPENRDLH----DMLLALAKAVANTTAALVLRAKNIAASCDDEQ---ARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQLEAAAKNVARAVNSLCEVCNE-ASNDPKLKADLLAAARDVSKSLTDMLEHVKLSS-REHANRTSTE-LSPVENV--IIGTDILVSTHDPQEMVRHARTLGQ---------TTAQLIQSIKGEADQQQ---DADMKRHLLSAAKQLADATAKLVEAARLCSSNPHDS-DNQNALRKAAEELREITTTAANTPAMKRGLIQRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVAD----TIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIEPALQVSKSSRALQPTVTD--IPSATQLS-----KGALHLGQCVSELHSVAQRARDACGGQELESALEEVRKLHDVLDDTRQAAIAGQLRPLPGQTVENTADELRKSAKNVGIALSQLLSSVLHNQRSYAGAAGRDTALALGDFTRS--------------VHGVAA----TTQNPAIIDCADDVVTSSARLIEQAQRTLQG-------ASNPEALTQAGREVTGALSATVDCIPGQREVDVALRNVSELSEILSMS--------EFPPSSRPYATLQSELKQVAEQLSSAGGEIVVSYSSPALLAESSQNFAANYRDLLSVSMEMAGQTQEEEVRSHMIESLRHVSTQSCSLLSTAKSIAADPGQPNAK---NLLHAAARGVTESINQLVDASIQSAP-GQKECDNAMRNIEALR--LMLDYPHEPINELGYFDCVEQATGKSRNLGYAISEMINNAKQSQHVEFSQSVNNVNDSIQGLIESSSQAAYLIGVSHP------SSVAGRPGIIDQAQLTWAYQGIRQHCDIVSSQQSTKPQMISALTVIAKHTSYLCSICRQASMNTSNPVAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRE--RLVDPLLEAVKAVRQYASSSEFSSVPAK-ISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQLSMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDSCALAVNAQGLSQRRDNNLHGFSGQTMN--------SASELIDKLEPIR--MAGKNNAEQLGHAVGEISRYVVPMVNGAIGACTHIVHSQQQMSLIQQTRSVVESAITLVQSAKESAGNPRATHAHPRLDDAIDGTREAIQELQQTVEKINAETGIVTGLMEQVNRSITRLTDKRQ-SLLNASYSDTFVDYQTRMVARAKEIASLANEMNAKSSVEPSALPQLAVDMTQNYQQLTQDSVGASTTTSSPDVAMRIRTTVIDLGRSVSSMIQSSAGGARPNDAGAQK-------------EIARSAR-----EVSEKVAQVLAALQAGSRGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLHSDGD----GSFADHREHILQTAKALVEDTKVLVTGAAGTQDQLANAAQNAVSTITQLAEAVKRGACSLGSTQP------------DSQVMVINAVKDVASALGDLINCTKL-ASGKSINDPSMQDLKESARVMVLNVSSLLKTVKAVEDEHTRGTRAMEATVEAISQEIRAMHSPPPVG----NTQV-----------------------GPEDLIRVTMNVTAATAKAVAAGTSNLQADIVSAANLGRRAISEMLIVCR-SVAWNCAETEELRSRTLE------------------------------AGTAVGESYRDLLSGILH---NCSADDRMHL-SRRVAKCVTDLVAMARLLKGSDWIDPEDPT---VIAENELLGAAASIDAAAKKLASLRPRRQADVKIELDENMKFDEMILEAAKGIMGASAALVRAANAAQRELIDTGKVARRP---LTSSDDGQWSEGLISAARLVAAATHSLVEAAQNLVRGVGTEEMLISTAKQVAASTAQLLIACKVKSNPNSEAGRRLQAAGNAVIKSTDNLVHSAQQGLEAEEEHSLKI-----NTSMVDGMAQEINARSAVLRKEKELEEARQLLKNVRHA 2512
BLAST of Talin vs. Ensembl Zebrafish
Match: tln1 (talin 1 [Source:ZFIN;Acc:ZDB-GENE-031002-48]) HSP 1 Score: 993.416 bits (2567), Expect = 0.000e+0 Identity = 858/2777 (30.90%), Postives = 1416/2777 (50.99%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDS--KIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAID---ELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXX--XXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRE-----LATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNN-------QDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDT----VTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMA-------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVR---SRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRS---NLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIR-VTIDMKLKEE-KSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLA--SRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHR-DVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + TVVYD CR + +R+P+ + ++GLF+SD D + WL+ K + YY L GD L +K + R L IR +D T KT+ VDDSK ++++++ IC ++GI+N++EYSL+ ++ E ++ +T TLKR KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G+ K K +LKEFLPKEYVK KG +K+I ++ ++ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ F N + + G + + + R G+ P +++ S + Q + Q + + L+ ++AL I +++ ++A LD+ + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N ++ + ++ + + ++E NG L+ AAK L A D+L ++P + E + L++A VG+AS LL I SD + +D L+ AK +AN + ++K +VA K ++ + Q +I AA +TS L++ +VVA +I P+ Q+QL + + V SV+ ++ ++ +Q+ + +++++L QH I + P+ + L ++ + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA ++V A K + + E QQ L +AA + + A I++RL LE A +Q A A Q + ++Q AA + + A+ Q+ + + + + P+++ + P P+AQ L+ A Q +Q +++ +++A P + D + L+ +N ++LA+L+ Q+A P + N + G L M A S A G+L PLPGET+E S +GSS+KA S +L + N NY G+ +A+++ +++ L ARG+AA ++ + L + +DC ++ +I+ K A + D L + + + ++ V +P +++D + +++ E K + + P K+ + Q+ A A NQ+ +L+ S T L + + + + L G+ + + + +Q Q+ + LK++S +S+ LL A + S+D N K L AA V+DSIN L+S C P Q+ C+++ R+LE + L E P+ +N+ Y C+ SV E S+ L M I K + +F ++ S + + ++ Q Y +G+ N+ V +P Q A +K I MA N + C + AT + S++C + + +S+P + + + + K VA +T NL+K+I + + + EN + K G ++ V+ LT A +NP ++ Q G A I A+ M+E S L++ A +L + K P + +T + +L ++ APGQRE + E L +R +D+A++ S ++ + + S + ++M S+ ++ N I P+ ++ ++ LG V + SY P+ ++ A + +S+ + V++ TKT+ E+ L M+ T T N + L E+V +K DDL + +AS G + M+ SI +S ++ + P T + ++ K I T VT ++ N D + L + +T E + S+ K A ++ KK V + TG++ +GA C Y +KE I R +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+F +N EN + + I E I K K LV D + +V QE LA A ++V +L VK A ++GS E Q +L+NAV+DVA AL D + TK A K D LK+S + MV +V L+K+VK++ED +GTRALE ++E +++E + P K + E + MTK + LA+ KA+AA + +QED++ AN+ R+A+ D++ + ++K E +++ R SE + + ++EH V +I + SH ++ LA S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR + K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A + VQG ++LIS++KQVAA TA LL+AC+VK+D DS+T +RLQAAG+AVKRA++ LVK A + + QD MV + +I AQ +++ KE+ELE R K IRQ
Sbjct: 1 MVALSLKIGVGNVVKTMQFEPSTVVYDACRIIRERVPEAQLGQPSDYGLFLSDDDPKKGIWLEAGKALDYYMLRNGD---TLEYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRDVGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEESEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYVKNKG-EKRIFQAHKNCQNMTEIEAKVNYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQF----------NKMGKV----ETGSVALPAIIRSGAGGPESMKMGSMPQAKQHITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAVQASLDEFDALPPLGTDSASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDP---AETDYTAVGCAVTTISSNLTEMSKGVKLLAAL---MEDEGGNGQQLLGAAKNLACAVSDMLKTAQPSSTE-----------------PRQNLLQAAGNVGQASGELLQQIGE-----SDADQHFQDMLMQLAKAVANAAA--ALVLKAKNVAQK-SEDSAQQNKVIAAATQCALSTSQLVACTRVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASHGATGDEHLL-KQVGAAATGVTQALNELLQH--IRQYASGGQPIGRHGEATDRILDVTDNIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGES------------DLENSRKLLSAAKLLADATARMVEAAKGAAANPD-SEEQQQKLREAAEGLRMATNAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQI-PQLVQGLRSSQAQPDSPSAQLALIGASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTMVRG----LERDMQEAKASAAEGKLRPLPGETLEKCSQDLGSSTKAVSSAIAQLLSEATQGNENY--------TGM------AARDVAQALRSLASAARGVAA-----NTEDPLARNAM--LDCTGDVMDKSASLIEETKRAIAKPGDPDSQQRLAQVAKAVSQALNRSVNCLPGQRDVD---NAIRTVGEASKKLLSDKFPA-----SGKNFQEAQANLNEAAAGLNQSANELVQASRGTTQDLAKASGKFGQDFNQFLQAGVDMAGQSQSKEDQTQVVTNLKTISMSSS-----KLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLISMCTQQAP-GQKECDNALRELETVGGML--ENPTEAVNDLGYFDCIDSVMENSKVLGEAMAGISHNAKNSNLPEFGDSVSSASKALCGLTEAAAQGAYLVGVSDPNSHAGQKGLV-DP-----SQFAR--AKQSIQMACQNLVDPACTQSQVLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKAIDGAFNQENRQKCKEATGPLIEAVDNLTAFA-----SNPEFASVPAQISPEGLAAMEPITAAAKAMLESSTGLIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLSNCIREVDKASLAAI----SQQLTPRDDISHEALHEQMAASVHEISNLIEPV--AIAARADASQLGHKVSQMVSYFEPLIMAAIGTASKILNSQQQMNVLDQTKTLAESALQMLY---TAKETGGNHKAAHTQEALEESVQMMKEAVDDLGSTLAEVASAAGAVGGMVNSITQSINKMEDGPAFEPEGTFVDYQTTMVKTAKAIAVTVQEMVTKSNTNPD-ELGGLANQLTT------EFGDLASEAKCAAMTAENDEIGSHIKKQVTELGYTCTGLVS--KAGALQ------------------CSPNDSYTKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMF-----ATAGTLNRENAETFADHRYYI-EHILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGS------------EDPETQVVLINAVKDVAKALGDLISATK----AAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIKQELAVFSSADP----------------------------PPKTATPEEFIRMTKGITLATAKAVAAGNSCRQEDVIATANLSRRAVADMLRSCKQAAYHPEVKREVQTRALRFGSE---------------CSTSYLGLLEH----VLVII--------------QKPSHDLKQQLANYSKRVASSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPR-AKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATNNLCEAANSAVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSQTMKRLQAAGNAVKRASDNLVKAAQKAAFEAQDDQAVMV----KSKMVGGIAQIIAAQEEMLRKEKELEEARKKLAMIRQ 2527
BLAST of Talin vs. Ensembl Zebrafish
Match: tln1 (talin 1 [Source:ZFIN;Acc:ZDB-GENE-031002-48]) HSP 1 Score: 981.089 bits (2535), Expect = 0.000e+0 Identity = 856/2778 (30.81%), Postives = 1414/2778 (50.90%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDS--KIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAK-VVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAID---ELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXX--XXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRE-----LATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNN-------QDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDT----VTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMA-------DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVR---SRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRS---NLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIR-VTIDMKLKEE-KSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLA--SRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHR-DVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + TVVYD CR + +R+P+ + ++GLF+SD D + WL+ K + YY L GD L +K + R L IR +D T KT+ VDDSK ++++++ IC ++GI+N++EYSL+ ++ E ++ +T TLKR KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G+ K K +LKEFLPKEYVK KG +K+I ++ ++ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ DFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ F N + + G + + + R G+ P +++ S + Q + Q + + L+ ++AL I +++ ++A LD+ + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N ++ + ++ + + ++E NG L+ AAK L A D+L ++P + E + L++A VG+AS LL I SD + +D L+ AK +AN + ++K +VA K ++ + Q +I AA +TS L++ + VVA +I P+ Q+QL + + V SV+ ++ ++ +Q+ + +++++L QH I + P+ + L ++ + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA ++V A K + + E QQ L +AA + + A I++RL LE A +Q A A Q + ++Q AA + + A+ Q+ + + + + P+++ + P P+AQ L+ A Q +Q +++ +++A P + D + L+ +N ++LA+L+ Q+A P + N + G L M A S A G+L PLPGET+E S +GSS+KA S +L + N NY G+ +A+++ +++ L ARG+AA ++ + L + +DC ++ +I+ K A + D L + + + ++ V +P +++D + +++ E K + + P K+ + Q+ A A NQ+ +L+ S T L + + + + L G+ + + + +Q Q+ + LK++S +S+ LL A + S+D N K L AA V+DSIN L+S C P Q+ C+++ R+LE + L E P+ +N+ Y C+ SV E S+ L M I K + +F ++ S + + ++ Q Y +G+ N+ V +P Q A +K I MA N + C + AT + S++C + + +S+P + + + + K VA +T NL+K+I + + + EN + K G ++ V+ LT A +NP ++ Q G A I A+ M+E S L++ A +L + K P + +T + +L ++ APGQRE + E L +R +D+A++ S ++ + + S + ++M S+ ++ N I P+ ++ ++ LG V + SY P+ ++ A + +S+ + V++ TKT+ E+ L M+ T T N + L E+V +K DDL + +AS G + M+ SI +S ++ + P T + ++ K I T VT ++ N D + L + +T E + S+ K A ++ KK V + TG++ +GA C Y +KE I R +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+F +N EN + + A +E I K K LV D + +V QE LA A ++V +L VK A ++GS E Q +L+NAV+DVA AL D + TK A K D LK+S + MV +V L+K+VK++ED +GTRALE ++E +++E + P K + E + MTK + LA+ KA+AA + +QED++ AN+ R+A+ D++ + ++K E +++ R SE + + ++EH V +I + SH ++ LA S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR + K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A + VQG ++LIS++KQVAA TA LL+AC+VK+D DS+T +RLQAAG+AVKRA++ LVK A + + QD MV + +I AQ +++ KE+ELE R K IRQ
Sbjct: 1 MVALSLKIGVGNVVKTMQFEPSTVVYDACRIIRERVPEAQLGQPSDYGLFLSDDDPKKGIWLEAGKALDYYMLRNGD---TLEYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRDVGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEESEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYVKNKG-EKRIFQAHKNCQNMTEIEAKVNYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWAASPK----DFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQF----------NKMGKV----ETGSVALPAIIRSGAGGPESMKMGSMPQAKQHITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAVQASLDEFDALPPLGTDSASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDP---AETDYTAVGCAVTTISSNLTEMSKGVKLLAAL---MEDEGGNGQQLLGAAKNLACAVSDMLKTAQPSSTE-----------------PRQNLLQAAGNVGQASGELLQQIGE-----SDADQHFQDMLMQLAKAVANAAA--ALVLKAKNVAQK-SEDSAQQNKVIAAATQCALSTSQLVACTRVVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASHGATGDEHLL-KQVGAAATGVTQALNELLQH--IRQYASGGQPIGRHGEATDRILDVTDNIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGES------------DLENSRKLLSAAKLLADATARMVEAAKGAAANPD-SEEQQQKLREAAEGLRMATNAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQI-PQLVQGLRSSQAQPDSPSAQLALIGASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTMVRG----LERDMQEAKASAAEGKLRPLPGETLEKCSQDLGSSTKAVSSAIAQLLSEATQGNENY--------TGM------AARDVAQALRSLASAARGVAA-----NTEDPLARNAM--LDCTGDVMDKSASLIEETKRAIAKPGDPDSQQRLAQVAKAVSQALNRSVNCLPGQRDVD---NAIRTVGEASKKLLSDKFPA-----SGKNFQEAQANLNEAAAGLNQSANELVQASRGTTQDLAKASGKFGQDFNQFLQAGVDMAGQSQSKEDQTQVVTNLKTISMSSS-----KLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLISMCTQQAP-GQKECDNALRELETVGGML--ENPTEAVNDLGYFDCIDSVMENSKVLGEAMAGISHNAKNSNLPEFGDSVSSASKALCGLTEAAAQGAYLVGVSDPNSHAGQKGLV-DP-----SQFAR--AKQSIQMACQNLVDPACTQSQVLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKALDGAFNQENRQKCKEATGPLIEAVDNLTAFA-----SNPEFASVPAQISPEGLAAMEPITAAAKAMLESSTGLIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLSNCIREVDKASLAAI----SQQLTPRDDISHEALHEQMAASVHEISNLIEPV--AIAARADASQLGHKVSQMVSYFEPLIMAAIGTASKILNSQQQMNVLDQTKTLAESALQMLY---TAKETGGNHKAAHTQEALEESVQMMKEAVDDLGSTLAEVASAAGAVGGMVNSITQSINKMEDGPAFEPEGTFVDYQTTMVKTAKAIAVTVQEMVTKSNTNPD-ELGGLANQLTT------EFGDLASEAKCAAMTAENDEIGSHIKKQVTELGYTCTGLVS--KAGALQ------------------CSPNDSYTKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMF-----ATAGTLNRENAE----TFADHREHILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGS------------EDPETQVVLINAVKDVAKALGDLISATK----AAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIKQELAVFSSADP----------------------------PPKTATPEEFIRMTKGITLATAKAVAAGNSCRQEDVIATANLSRRAVADMLRSCKQAAYHPEVKREVQTRALRFGSE---------------CSTSYLGLLEH----VLVII--------------QKPSHDLKQQLANYSKRVASSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPR-AKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATNNLCEAANSAVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSQTMKRLQAAGNAVKRASDNLVKAAQKAAFEAQDDQAVMV----KSKMVGGIAQIIAAQEEMLRKEKELEEARKKLAMIRQ 2521
BLAST of Talin vs. Ensembl Zebrafish
Match: tln2a (talin 2a [Source:ZFIN;Acc:ZDB-GENE-040724-263]) HSP 1 Score: 971.844 bits (2511), Expect = 0.000e+0 Identity = 835/2772 (30.12%), Postives = 1422/2772 (51.30%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGS------AQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLL------TDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSIT-----AHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRV--ANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVP--NNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHA---SVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKT----ITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQL--SLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+L+I + N +++ + T VYD CR + +R+P+ + E+GLF+SD D + WL+ + + YY L GD +L +K + R ++ +D KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +R+ K+EK+K KL TDD+LNWL HG+T R+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K K+ +LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+G++KE VMRVDEKTK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE M+EE+V+P K+ ++ F E S+A LP G++ G VG+ P A + GQ ++ P LS ++AL+ I +++ ++ A +DL++ E+ LG+D +S+ + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + ++E +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ +A + L + V V E SV Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+ ++ + + + + ++ +++ L H + N T D ++ +E + +++G++ EMV QA++LA+A ++L + + + A V+ NN + ++ A+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + +SQ AA + + A++ Q+ + + + + P+++ + P D +AQ L+ A + +Q +++ S+++ P V D + L +N T+LA+L+ Q A P + A IA +QTL + + A + + G+L PLPGE++E + +G +SKA +L N + + G+ +A E ++++ L + ARG+AA S + + +V++ ++I ++ + A I+ L + + ++ V +P +++D LKS E K ++ P +KS + QS+ A NQ+ GD+++ S T + L + + +++ D L G+++ P ++Q Q+ LK++S S+ LL K L G+ K L AA V+DSIN L++ C P Q+ C+++ R+LEA++ L + P+ P+N+ SY C++SV E S+ L M I CKTGD F + S + + ++ QA+Y +G+ SS +P L IQ A + C ++ ++S AT + S++C + + +++P + + + K VA +T NL+KTI + S EN E + A ++ V+ LT A +NP + I+ +G AQ I Q++ M++ S LL+ A +LV + K P + +T + L ++ APGQ+E + + + +R++++A++ S N D ++S+ + QL S++++ + I PI + + + LG V + SY P+ +S +A + + +++ TKT+ E+ L M+ +E ++ D + + L + DDL+ ++ AS G + M+ SI S +L E P + +Q+ T +K I+V+ ++ TK + + ED L+ ++ DY L V ++S ++ ++K V +G C+ L++ + ++E I R+ +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+F + +N+END +S A +E+I K K+LV D + +V QE LA A ++ + QL VK A +IG + Q +L+NAV+DVA AL + + TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +R+E ++ + +K + E + MTK + A+ KA+AA + +QED++ AN+ RK I D++ + F+E+ + E + + +G ID+ E++ + + K K ++ + S+++A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + ++ D + T V + +I AQ +++ KERELE R K IRQ
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASEYGLFLSDEDPRKGIWLEGGRTLDYYMLRNGD---ILEYKKKQRPQKVKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKDEGTGTLKKDRTLLREERKMEKLKAKLHTDDDLNWLDHGRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQTQIQFGPHIEHKHKTGFLDLKEFLPKEYIKQRGAEKKIFQEHKGCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEEATMLEESVSPKKSTILQQQF--NRVGRVEHGSVA----LP-----GILRSGSVGAETLNMGTMP-APQQQITTGQMHLGHMP------PLSAAQQALVGTINTSMQAVQQAQDDLEEVEELPPLGDDMASKMWIQNKMDESKHDIHSQVDAITAGTASVVNLTAGDP---TDTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGHDLMRAARTLTGAVSDLLKAVEPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMNLAKAVANAAAMMVLKAKNVAQVSEDSV---------MQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVEGCVKACLSAT-SDGELLKAVSAAAGIVTQALSDLLTH-VRNYATRGEPIGRYDQATDTIMNVTENIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEVEVDVNNSKKLLAA------------AKLLADATARMVEAAKGAAAYPENE-DQQQKLREAAEGLRVATNAAAQNAIKKKLITRLENAAKQAAAAATQTIAASQNAAASNKNTAAHQQLVQSCRAVADHI-PQLVQGVRGSQGQPEDGSAQLALIIASKNFLQPGSKMVSSAKSSVPTVTDQAAAMQLGQCAKNLATTLAELRTAAQTAHEACGPMEIDSALIA------VQTLKNELQDAKMAASEGQLKPLPGESLEKCAQDLGGTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AASETAQALKTLAQAARGVAATTSDPAGAAAMLDSAREVMEGSAKLISEAKEALVAPGDAEIQ----QRLAQVAKAVSHSLNACVNCLPGQKDVDM---ALKSIGEASKKLLVETLPPC-----SKSFQEAQSDLNQTAADLNQSAGDVVHASRGTTTQLADASGKFSDNFDEFLDAGIEMAGHTPGKDDQLQVIGNLKNISMASSKLLLAAKSLSVDPGA---GNAKNLLAAAARSVTDSINQLITMCTQNAP-GQRECDNALRELEAVRG--LLDNPNEPVNDLSYFDCIESVMENSKVLGESMAGISHNCKTGDVPAFGDCVGGASKALCGLTEAAGQASYLVGVSDP------SSQAGHPGLVDPIQFARANQAIQMACQNLVDPDSSPSQVLSAATIVAKHTSALCNACRLASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENREKCRIATAPLIEAVDNLTIFA-----SNPEFASVPAQISREGSAAQEPIIQSARSMLDSSTHLLKTARSLVMNPKDPPTWSLLAGHSRTVSDSIKSLITAIRDKAPGQKECDSAIDNINKCIRDIEQASLAAVS------QNLPRRDEVSSEALQEQLTSSVQEVGHLIEPITT--AAKGEAAQLGHKVSQLVSYFTPLVSASMGIASKTLDHQQQMNLLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMREAVDDLLLTLNEAASEVGMVSGMVDSIADSMGKLGEGTPPEP----EGSFVEYQT--------TMVRYSKAIAVS--AQEMITKSVSSPEDLCSLA-----------SQVTADYSQL--AVQGRLASATAEPEEIGFQIKTSVQELGHGCIVLVQKAGALQISPTDSFTKRELIECARAVTEKVSMVLSALQAGNKGTQACITAASAVSGIIADLDTTIMF-----ASAGTLNAENDS---DSFADHRENILKTAKALVEDTKNLVSGAASSQEKLAQAAQSSAKTITQLTDVVKLGAASIGPDDP------------ETQVVLINAVKDVAKALAELISATKCAAGKAAD-DPSMFQLKSAAKVMVTNVTSLLKTVKAVEDEASRGTRALEATIECIRQELTMFQS----------------------------KETPEKSSTPEEFIRMTKGITTATAKAVAAGNSARQEDVISTANLSRKVIADMLTSCK--------------QAAFNEEVSV-------------EVRSRALLYGTECTNGYIDLLEHVLQVLQ--KPTGDQKQKLAMFSKKVAAAVTELIQTAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADESLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATSNLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFNKADDDNVVVKTR------FVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2528
BLAST of Talin vs. Ensembl Zebrafish
Match: tln2a (talin 2a [Source:ZFIN;Acc:ZDB-GENE-040724-263]) HSP 1 Score: 968.378 bits (2502), Expect = 0.000e+0 Identity = 835/2772 (30.12%), Postives = 1422/2772 (51.30%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGS------AQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLL------TDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSIT-----AHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRV--ANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVP--NNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHA---SVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKT----ITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQL--SLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+L+I + N +++ + T VYD CR + +R+P+ + E+GLF+SD D + WL+ + + YY L GD +L +K + R ++ +D KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +R+ K+EK+K KL TDD+LNWL HG+T R+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K K+ +LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+G++KE VMRVDEKTK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE M+EE+V+P K+ ++ F E S+A LP G++ G VG+ P A + GQ ++ P LS ++AL+ I +++ ++ A +DL++ E+ LG+D +S+ + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + ++E +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ +A + L + V V E SV Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+ ++ + + + + ++ +++ L H + N T D ++ +E + +++G++ EMV QA++LA+A ++L + + + A V+ NN + ++ A+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + +SQ AA + + A++ Q+ + + + + P+++ + P D +AQ L+ A + +Q +++ S+++ P V D + L +N T+LA+L+ Q A P + A IA +QTL + + A + + G+L PLPGE++E + +G +SKA +L N + + G+ +A E ++++ L + ARG+AA S + + +V++ ++I ++ + A I+ L + + ++ V +P +++D LKS E K ++ P +KS + QS+ A NQ+ GD+++ S T + L + + +++ D L G+++ P ++Q Q+ LK++S S+ LL K L G+ K L AA V+DSIN L++ C P Q+ C+++ R+LEA++ L + P+ P+N+ SY C++SV E S+ L M I CKTGD F + S + + ++ QA+Y +G+ SS +P L IQ A + C ++ ++S AT + S++C + + +++P + + + K VA +T NL+KTI + S EN E + A ++ V+ LT A +NP + I+ +G AQ I Q++ M++ S LL+ A +LV + K P + +T + L ++ APGQ+E + + + +R++++A++ S N D ++S+ + QL S++++ + I PI + + + LG V + SY P+ +S +A + + +++ TKT+ E+ L M+ +E ++ D + + L + DDL+ ++ AS G + M+ SI S +L E P + +Q+ T +K I+V+ ++ TK + + ED L+ ++ DY L V ++S ++ ++K V +G C+ L++ + ++E I R+ +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+F + +N+END +S A +E+I K K+LV D + +V QE LA A ++ + QL VK A +IG + Q +L+NAV+DVA AL + + TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +R+E ++ + +K + E + MTK + A+ KA+AA + +QED++ AN+ RK I D++ + F+E+ + E + + +G ID+ E++ + + K K ++ + S+++A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + ++ D + T V + +I AQ +++ KERELE R K IRQ
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASEYGLFLSDEDPRKGIWLEGGRTLDYYMLRNGD---ILEYKKKQRPQKVKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKDEGTGTLKKDRTLLREERKMEKLKAKLHTDDDLNWLDHGRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQTQIQFGPHIEHKHKTGFLDLKEFLPKEYIKQRGAEKKIFQEHKGCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEEATMLEESVSPKKSTILQQQF--NRVGRVEHGSVA----LP-----GILRSGSVGAETLNMGTMP-APQQQITTGQMHLGHMP------PLSAAQQALVGTINTSMQAVQQAQDDLEEVEELPPLGDDMASKMWIQNKMDESKHDIHSQVDAITAGTASVVNLTAGDP---TDTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGHDLMRAARTLTGAVSDLLKAVEPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMNLAKAVANAAAMMVLKAKNVAQVSEDSV---------MQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVEGCVKACLSAT-SDGELLKAVSAAAGIVTQALSDLLTH-VRNYATRGEPIGRYDQATDTIMNVTENIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEVEVDVNNSKKLLAA------------AKLLADATARMVEAAKGAAAYPENE-DQQQKLREAAEGLRVATNAAAQNAIKKKLITRLENAAKQAAAAATQTIAASQNAAASNKNTAAHQQLVQSCRAVADHI-PQLVQGVRGSQGQPEDGSAQLALIIASKNFLQPGSKMVSSAKSSVPTVTDQAAAMQLGQCAKNLATTLAELRTAAQTAHEACGPMEIDSALIA------VQTLKNELQDAKMAASEGQLKPLPGESLEKCAQDLGGTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AASETAQALKTLAQAARGVAATTSDPAGAAAMLDSAREVMEGSAKLISEAKEALVAPGDAEIQ----QRLAQVAKAVSHSLNACVNCLPGQKDVDM---ALKSIGEASKKLLL--PPC------SKSFQEAQSDLNQTAADLNQSAGDVVHASRGTTTQLADASGKFSDNFDEFLDAGIEMAGHTPGKDDQLQVIGNLKNISMASSKLLLAAKSLSVDPGA---GNAKNLLAAAARSVTDSINQLITMCTQNAP-GQRECDNALRELEAVRG--LLDNPNEPVNDLSYFDCIESVMENSKVLGESMAGISHNCKTGDVPAFGDCVGGASKALCGLTEAAGQASYLVGVSDP------SSQAGHPGLVDPIQFARANQAIQMACQNLVDPDSSPSQVLSAATIVAKHTSALCNACRLASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENREKCRIATAPLIEAVDNLTIFA-----SNPEFASVPAQISREGSAAQEPIIQSARSMLDSSTHLLKTARSLVMNPKDPPTWSLLAGHSRTVSDSIKSLITAIRDKAPGQKECDSAIDNINKCIRDIEQASLAAVS------QNLPRRDEVSSEALQEQLTSSVQEVGHLIEPITT--AAKGEAAQLGHKVSQLVSYFTPLVSASMGIASKTLDHQQQMNLLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMREAVDDLLLTLNEAASEVGMVSGMVDSIADSMGKLGEGTPPEP----EGSFVEYQT--------TMVRYSKAIAVS--AQEMITKSVSSPEDLCSLA-----------SQVTADYSQL--AVQGRLASATAEPEEIGFQIKTSVQELGHGCIVLVQKAGALQISPTDSFTKRELIECARAVTEKVSMVLSALQAGNKGTQACITAASAVSGIIADLDTTIMF-----ASAGTLNAENDS---DSFADHRENILKTAKALVEDTKNLVSGAASSQEKLAQAAQSSAKTITQLTDVVKLGAASIGPDDP------------ETQVVLINAVKDVAKALAELISATKCAAGKAAD-DPSMFQLKSAAKVMVTNVTSLLKTVKAVEDEASRGTRALEATIECIRQELTMFQS----------------------------KETPEKSSTPEEFIRMTKGITTATAKAVAAGNSARQEDVISTANLSRKVIADMLTSCK--------------QAAFNEEVSV-------------EVRSRALLYGTECTNGYIDLLEHVLQVLQ--KPTGDQKQKLAMFSKKVAAAVTELIQTAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADESLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATSNLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFNKADDDNVVVKTR------FVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2525
BLAST of Talin vs. Ensembl Zebrafish
Match: tln2b (talin 2b [Source:ZFIN;Acc:ZDB-GENE-130325-1]) HSP 1 Score: 455.677 bits (1171), Expect = 1.633e-131 Identity = 480/1687 (28.45%), Postives = 819/1687 (48.55%), Query Frame = 3
Query: 3219 QLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEV--PNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMS-KNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKAN-EDNQILSQNKMADVNYPFKKLVHDYDSLV--TGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYEN----LNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE--HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+++ SS+A P V D + L +N T LA+L+ Q+A P + + + +QTL S + A + +L PLPGE++E + +GS+SKA +L N + + G+ +A+E +++ L + ARG+AA + + + + V++ +I + + A + L + + ++ V +P +++D L+S E K ++ N P +KS + Q++ A N + GD++ S+ S+ L + + + ++ D L G+++ ++Q Q+ S LK++S S+ LL K L G+++ L + +A V++SIN L++ C P Q+ C+++ R+LEA++ L + P+ P+++ SY C++SV E S+ L M I CKTG+ F + V S + + ++ QA+Y +G+ N S + +PI + A M+ +N + ASS + + AT + S++C + + +++P + + + K VA T NL+KTI + S EN E + A ++ V+ L+ A +NP +I Q G AQ I +++ M++ S LL A +L+ + K P + +T + L ++ APGQRE + + + + +R++++ ++ +V +S + + + S+ + + + +++++ + I PI + + + LG V + SY P+ +S LA + + +++ TKT+ E+ L M+ +E T+ D + + L K DD+M ++ AS G + M+ SI +S R++++N L +Q K +T L ++V Q + + A E ++ SQ + ++L H LV G +Q+ + +F ++ L +C AV + +++ ++ LQ+ ++GTQ CI AA+SV+ ++ADLDT I+FA +G+ +N+EN++ S A +E+I K K+LV D + +V Q+ LA A ++ + QL VK LG + M E Q +L+NAVRDVA AL + + TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E V SK DN +K + E + MTK + +A+ KA+AA + +QED++ AN+ RKAI+D++ K+ P E V+ K + +G +D+ E+ L K AE K Q+ S+++A S+ E+ ++A +K + D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + +D S+ V + +I AQ +++ KERELE R K IRQ
Sbjct: 13 KMVTSSKAAVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPLEIDSALSA----VQTLKSELQDAKMAALDLQLKPLPGESLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALRTLAQAARGVAASTVEPQAAAAMLDSAYHVMEGSAMLIHEAHQAL----VCPGDAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALRSIGEASKKLLVENLPPC-----SKSFQEAQTDLNHTAAELNHSAGDVVQSSRGSSSQLAVASGKFSQDFDEFLDAGIEMAGHTQSKDDQIQVISNLKNISMASSKLLLAAKSLSVDPGAANAKNLLAAAARA---VTESINQLITLCTQQAP-GQKECDNALRELEAVRGML--DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQHCKTGNVPAFGDCVGVASKALCGLTEAAGQASYLVGVSDPN-SQSGHQGLVDPIQFARANQAIQMACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRLASSKTANPVARRHFVQSAKEVANTTANLVKTIKALDGDFSDENRERCRVATTPLIEAVDNLSTFA-----SNPEFASIPAQISHEGSAAQEPIVRSARSMLDSSTHLLETARSLIINPKDPPTWSILAGHSRTVSDSIKSLITSIRDKAPGQRECDQSIDSINKSIRDIEQVSL--AAVGQS--LPRRDDISLEALQELLTSAVQEIGHLIDPIST--AARGEAAQLGHKVTQLASYFEPVIVASVGLASKHADHQQQMNILDQTKTLFESALQMLYAAKEGGGNPKATHTHDAISEAAQLMKEAVDDIMVTLNEAASEGGMVGGMVESIAESIGRVSDSN----LYIYIYIYCKYQMTKSVTCPEELGGLASQVTVDYSQLAQQGRLAAATAELEEVGSQ-----IKTRVQELGHGCIYLVQKAGALQMSPTDSFTKRE----LIECARAVTE-------------------KVSMVLSALQAGNKGTQACITAASSVSGIIADLDTTIMFASAGT-----LNAENEE----SFADHRENILKTAKALVEDTKLLVSGAASSQDKLAQAAQSSAKTITQLTDVVK------------LGAASMGSEDPETQVVLINAVRDVAKALAELISATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELT-----------VFQSK-------------DN----PEKSTTPEEFIRMTKGITVATAKAVAAGNSAQQEDVISTANLSRKAISDML--------TTCKQAAYHP----------------EVGEDVRN---KALLYGIECTTGYVDLLEHVLLVLQKPTAE------QKQQLASLSKKVASSVTELIQTAEAMKGSEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADESLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAV---DDGQWSQGLISAARMVAAATSNLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVKAAQKAAFDKAEDDSVVV-----KTKFVGGIAQIIAAQEEMLRKERELEEARKKLAHIRQ 1522
BLAST of Talin vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 978.778 bits (2529), Expect = 0.000e+0 Identity = 845/2784 (30.35%), Postives = 1434/2784 (51.51%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNV-------------QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMS-KNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDL-------VHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKP-SENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T VYD CR + +R+ + ++ +FGLF+SD D + WL+ + + YY L GD VL +K + R IR +D K + VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + +T TLK+ +T +RD K+EK+K KL T+DELNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K K LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ I + P + ++G V A P IR+ S G NV Q + + L+ ++ALM I ++ ++ A DL + + LG+D +SR + + +D +K + + ++T T +++ + D DY + AI TI N ++ + ++ + + ++E +G L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + T+ T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N + E ++ +Q+ +++ ++++ L QH + + +P+ +S +E + +++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ A+ + + A++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + + +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA S + ++ + DV++ +I+ + + A I+ L + + ++ V +P +++D LKS E K ++++ P TKS + QSE A NQ+ G++++++ S L + + ++ D L G+++ + N +Q Q+ LK++S S+ LL K L SG+ L AA V++SIN L++ C P Q+ C+++ R+LE +K L E P+ P ++ SY C++SV E S+ L M I KTGD F + V S + + ++ QA Y +G+ N+ V +PI + A M+ +N + ASS + + AT + S++C + + +++P + + + K VA +T NL+KTI + S EN ++ + A +++ VE LT A +NP +I Q G +AQ I +++ M+E S SL++ A +L + K P + + + + L ++ APGQRE + + + + +R++++A++ SV++ M D I+ + + QL+ ++++ + I PI + + + LG V + Y P+ ++ L + + + V++ TKT+ E+ L M+ +E + D + + L K DDLM ++ AS G + M+ SI ++ ++L E P T + G+ +K I+VT ++ TK + E+ L+ ++ DY +L V M++ ++ ++K + +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI A+++V+ ++ADLDT I+F +N+EN + S A +E+I K K+LV D + +V QE LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + A+ KA+AA + +QED++ AN+ RKA++++ V+H V D + R F +G A ++M E++ S+ + E+ K Q+++ S+RIA ++ E+ ++ +K T D +DP IAE ELL AA+ IE AAKK+ LKPR ++ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ + N + ++ QWS GLISAAR+VAAAT NL +SA A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ P
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD---VLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETMEEKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQQITR----------------PGKPELGTV-------ALPAIIRSGSS-GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGD---PTETDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGE-----------------PRQTVLTAAGSIGQASGELLRQIGENE---ADERFQVFDVLMNLAKAVANAAAMLV--LKAKNVA-QVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELL-KQVSAAASVVSQALNDLLQH--VRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHI-PQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNA----VQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTSDPQAASDMLDSARDVMEGSANLIQEAKQALVAPGDAEIQ----QRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGESSKKLLVDSLP-----PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQDFDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAK---NLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--ENPNEPASDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLV-DPIQFARANQAIQMACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFA-----SNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECDQSIDSINRFIRDIEQASL--ASVSQDLAM----RDDISLEALQEQLTSVVQEIGHLIDPITT--AARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEP-----TGTFVDYQTTGV-------KYSKAIAVT--AQEMMTKSVTNPEELGGLA-----------SQVTSDYGNL--AVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMF-----ATAGTLNAENKE----SFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALGDLIEATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEHIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITTATAKAVAAGNSCRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTR--------QRAF--------------------------RYGTECTFAYLEMLEHV-LSILQKPSLET-KQQLSIFSKRIAAAVTELIQTTETMKGTEWVDPQDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPRQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIAANAA--DDGQWSQGLISAARMVAAATSNLCESANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFSKAEEDDVVVKT------KFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLP 2537
BLAST of Talin vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 969.148 bits (2504), Expect = 0.000e+0 Identity = 840/2769 (30.34%), Postives = 1421/2769 (51.32%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNV-------------QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMS-KNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDL-------VHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKP-SENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T VYD CR + +R+ + ++ +FGLF+SD D + WL+ + + YY L GD VL +K + R IR +D K + VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + +T TLK+ +T +RD K+EK+K KL T+DELNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K K LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ I + P + ++G V A P IR+ S G NV Q + + L+ ++ALM I ++ ++ A DL + + LG+D +SR + + +D +K + + ++T T +++ + D DY + AI TI N ++ + ++ + + ++E +G L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + T+ T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N + E ++ +Q+ +++ ++++ L QH + + +P+ +S +E + +++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ A+ + + A++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + + +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA S + ++ + DV++ +I+ + + A I+ L + + ++ V +P +++D LKS E K ++++ P TKS + QSE A NQ+ G++++++ S L + + ++ D L G+++ + N +Q Q+ LK++S S+ LL K L SG+ L AA V++SIN L++ C P Q+ C+++ R+LE +K L E P+ P ++ SY C++SV E S+ L M I KTGD F + V S + + ++ QA Y +G+ N+ V +PI + A M+ +N + ASS + + AT + S++C + + +++P + + + K VA +T NL+KTI + S EN ++ + A +++ VE LT A +NP +I Q G +AQ I +++ M+E S SL++ A +L + K P + + + + L ++ APGQRE + + + + +R++++A++ SV++ M D I+ + + QL+ ++++ + I PI + + + LG V + Y P+ ++ L + + + V++ TKT+ E+ L M+ +E + D + + L K DDLM ++ AS G + M+ SI ++ ++L E P T + G+ +K I+VT A E ++++ D+ + LV G +QI + ++ ++ L +C AV + +++ ++ LQ+ ++GTQ CI A+++V+ ++ADLDT I+F +N+EN + S A +E+I K K+LV D + +V QE LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + A+ KA+AA + +QED++ AN+ RKA++++ V+H V D + R F +G A ++M E++ S+ + E+ K Q+++ S+RIA ++ E+ ++ +K T D +DP IAE ELL AA+ IE AAKK+ LKPR ++ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ + N + ++ QWS GLISAAR+VAAAT NL +SA A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ P
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD---VLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETMEEKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQQITR----------------PGKPELGTV-------ALPAIIRSGSS-GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGD---PTETDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGE-----------------PRQTVLTAAGSIGQASGELLRQIGENE---ADERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELL-KQVSAAASVVSQALNDLLQH--VRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHI-PQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNA----VQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTSDPQAASDMLDSARDVMEGSANLIQEAKQALVAPGDAEIQ----QRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGESSKKLLVDSLP-----PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQDFDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAK---NLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--ENPNEPASDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLV-DPIQFARANQAIQMACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFA-----SNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECDQSIDSINRFIRDIEQASL--ASVSQDLAM----RDDISLEALQEQLTSVVQEIGHLIDPITT--AARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEP-----TGTFVDYQTTGV-------KYSKAIAVT------------AQEMVGFQIKSRIQDLGHGCIFLVQK-----AGALQICPTDSYTKRE----LIECARAVTE-------------------KVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMF-----ATAGTLNAENKE----SFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALGDLIEATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEHIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITTATAKAVAAGNSCRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTR--------QRAF--------------------------RYGTECTFAYLEMLEHV-LSILQKPSLET-KQQLSIFSKRIAAAVTELIQTTETMKGTEWVDPQDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPRQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIAANAA--DDGQWSQGLISAARMVAAATSNLCESANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFSKAEEDDVVVKT------KFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLP 2495
BLAST of Talin vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 967.607 bits (2500), Expect = 0.000e+0 Identity = 841/2782 (30.23%), Postives = 1421/2782 (51.08%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNV-------------QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMS-KNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDL-------VHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKP-SENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T VYD CR + +R+ + ++ +FGLF+SD D + WL+ + + YY L GD VL +K + R IR +D K + VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + +T TLK+ +T +RD K+EK+K KL T+DELNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K K LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ I + P + ++G V A P IR+ S G NV Q + + L+ ++ALM I ++ ++ A DL + + LG+D +SR + + +D +K + + ++T T +++ + D DY + AI TI N ++ + ++ + + ++E +G L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + T+ T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N + E ++ +Q+ +++ ++++ L QH + + +P+ +S +E + +++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ A+ + + A++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + + +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA S + ++ + DV++ +I+ + + A I+ L + + ++ V +P +++D LKS E K ++++ P TKS + QSE A NQ+ G++++++ S L + + ++ D L G+++ + N +Q Q+ LK++S S+ LL K L SG+ L AA V++SIN L++ C P Q+ C+++ R+LE +K L E P+ P ++ SY C++SV E S+ L M I KTGD F + V S + + ++ QA Y +G+ N+ V +PI + A M+ +N + ASS + + AT + S++C + + +++P + + + K VA +T NL+KTI + S EN ++ + A +++ VE LT A +NP +I Q G +AQ I +++ M+E S SL++ A +L + K P + + + + L ++ APGQRE + + + + +R++++A++ SV++ M D I+ ++ Q LG V + Y P+ ++ L + + + V++ TKT+ E+ L M+ +E + D + + L K DDLM ++ AS G + M+ SI ++ ++L E P T + G+ +K I+VT ++ TK + E+ L+ ++ DY +L V M++ ++ ++K + +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI A+++V+ ++ADLDT I+F +N+EN + S A +E+I K K+LV D + +V QE LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + A+ KA+AA + +QED++ AN+ RKA++++ V+H V D + R F +G A ++M E++ S+ + E+ K Q+++ S+RIA ++ E+ ++ +K T D +DP IAE ELL AA+ IE AAKK+ LKPR ++ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ + N + ++ QWS GLISAAR+VAAAT NL +SA A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ P
Sbjct: 9 SLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD---VLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETMEEKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQQITR----------------PGKPELGTV-------ALPAIIRSGSS-GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGD---PTETDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGE-----------------PRQTVLTAAGSIGQASGELLRQIGENE---ADERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELL-KQVSAAASVVSQALNDLLQH--VRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHI-PQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNA----VQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTSDPQAASDMLDSARDVMEGSANLIQEAKQALVAPGDAEIQ----QRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGESSKKLLVDSLP-----PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQDFDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAK---NLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--ENPNEPASDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLV-DPIQFARANQAIQMACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFA-----SNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECDQSIDSINRFIRDIEQASL--ASVSQDLAM----RDDISLEVSAAQ-------------------------LGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEP-----TGTFVDYQTTGV-------KYSKAIAVT--AQEMMTKSVTNPEELGGLA-----------SQVTSDYGNL--AVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMF-----ATAGTLNAENKE----SFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALGDLIEATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEHIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITTATAKAVAAGNSCRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTR--------QRAF--------------------------RYGTECTFAYLEMLEHV-LSILQKPSLET-KQQLSIFSKRIAAAVTELIQTTETMKGTEWVDPQDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPRQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIAANAA--DDGQWSQGLISAARMVAAATSNLCESANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFSKAEEDDVVVKT------KFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLP 2514
BLAST of Talin vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 810.061 bits (2091), Expect = 0.000e+0 Identity = 709/2434 (29.13%), Postives = 1241/2434 (50.99%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNV-------------QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMS-KNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDL-------VHHIRVTIDMK 7196
+L+I + N +++ + T VYD CR + +R+ + ++ +FGLF+SD D + WL+ + + YY L + + VL +K + R IR +D K + VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + +T TLK+ +T +RD K+EK+K KL T+DELNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K K LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ I + P + ++G V A P IR+ S G NV Q + + L+ ++ALM I ++ ++ A DL + + LG+D +SR + + +D +K + + ++T T +++ + D DY + AI TI N ++ + ++ + + ++E +G L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + T+ T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N + E ++ +Q+ +++ ++++ L QH + + +P+ +S +E + +++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ A+ + + A++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + + +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA S + ++ + DV++ +I+ + + A I+ L + + ++ V +P +++D LKS E K ++++ P TKS + QSE A NQ+ G++++++ S L + + ++ D L G+++ + N +Q Q+ LK++S S+ LL K L SG+ L AA V++SIN L++ C P Q+ C+++ R+LE +K L E P+ P ++ SY C++SV E S+ L M I KTGD F + V S + + ++ QA Y +G+ N+ V +PI + A M+ +N + ASS + + AT + S++C + + +++P + + + K VA +T NL+KTI + S EN ++ + A +++ VE LT A +NP +I Q G +AQ I +++ M+E S SL++ A +L + K P + + + + L ++ APGQRE + + + + +R++++A++ SV++ M D I+ + + QL+ ++++ + I PI + + + LG V + Y P+ ++ L + + + V++ TKT+ E+ L M+ +E + D + + L K DDLM ++ AS G + M+ SI ++ ++L E P T + G+ +K I+VT ++ TK + E+ L+ ++ DY +L V M++ ++ ++K + +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI A+++V+ ++ADLDT I+F +N+EN + S A +E+I K K+LV D + +V QE LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + A+ KA+AA + +QED++ AN+ RKA++++ V+H V D +
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAVYDACRIIRERVSEAQSGQALDFGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD-VLEYKKKHRPQKIRMLDGAAKMILVDDSKTVGELLVTICSRIGITNYEEYSLIRETMEEKKEEQTGTLKKDRTLLRDEKKMEKLKAKLHTEDELNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQAQIQFGPHVESKHKPGFLELKEFLPKEYMKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQQITR----------------PGKPELGTV-------ALPAIIRSGSS-GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---TETDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGE-----------------PRQTVLTAAGSIGQASGELLRQIGENE---ADERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELL-KQVSAAASVVSQALNDLLQH--VRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHI-PQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNA----VQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTSDPQAASDMLDSARDVMEGSANLIQEAKQALVAPGDAEIQ----QRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGESSKKLLVDSLP-----PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQDFDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAK---NLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--ENPNEPASDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLV-DPIQFARANQAIQMACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFA-----SNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECDQSIDSINRFIRDIEQASL--ASVSQDLAM----RDDISLEALQEQLTSVVQEIGHLIDPITT--AARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEP-----TGTFVDYQTTGV-------KYSKAIAVT--AQEMMTKSVTNPEELGGLA-----------SQVTSDYGNL--AVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMF-----ATAGTLNAENKE----SFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALGDLIEATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEHIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITTATAKAVAAGNSCRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTR 2235
BLAST of Talin vs. Ensembl Xenopus
Match: TLN2 (talin 2 [Source:NCBI gene;Acc:100144637]) HSP 1 Score: 702.975 bits (1813), Expect = 0.000e+0 Identity = 716/2490 (28.76%), Postives = 1237/2490 (49.68%), Query Frame = 3
Query: 948 DVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNV-------------QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMS-KNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDL-------VHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKP-SENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+ KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ I + P + ++G V A P IR+ S G NV Q + + L+ ++ALM I ++ ++ A DL + + LG+D +SR + + +D +K + + ++T T +++ + D DY + AI TI N ++ + ++ + + ++E +G L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + T+ T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N + E ++ +Q+ +++ ++++ L QH + + +P+ +S +E + +++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ A+ + + A++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + + +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA S + ++ + DV++ +I+ + + A I+ L + + ++ V +P +++D LKS E K ++++ P TKS + QSE A NQ+ G++++++ S L + + ++ D L G+++ + N +Q Q+ LK++S S+ LL K L SG+ L AA V++SIN L++ C P Q+ C+++ R+LE +K L E P+ P ++ SY C++SV E S+ L M I KTGD F + V S + + ++ QA Y +G+ N+ V +PI + A M+ +N + ASS + + AT + S++C + + +++P + + + K VA +T NL+KTI + S EN ++ + A +++ VE LT A +NP +I Q G +AQ I +++ M+E S SL++ A +L + K P + + + + L ++ APGQRE + + + + +R++++A++ SV++ M D I+ + + QL+ ++++ + I PI + + + LG V + Y P+ ++ L + + + V++ TKT+ E+ L M+ +E + D + + L K DDLM ++ AS G + M+ SI ++ ++L E P T + G+ +K I+VT ++ TK + E+ L+ ++ DY +L V M++ ++ ++K + +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI A+++V+ ++ADLDT I+F +N+EN + S A +E+I K K+LV D + +V QE LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + A+ KA+AA + +QED++ AN+ RKA++++ V+H V D + R F +G A ++M E++ S+ + E+ K Q+++ S+RIA ++ E+ ++ +K T D +DP IAE ELL AA+ IE AAKK+ LKPR ++ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ + N + ++ QWS GLISAAR+VAAAT NL +SA A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ P
Sbjct: 20 EAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQQITR----------------PGKPELGTV-------ALPAIIRSGSS-GPETFNVGSMPSAQQQLTTGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAHSDLSQVDNLPPLGHDMASRVWIQNKVDESKHEIHSQVDAITAGTASVVNLTAGD---PTETDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGEKLLGAARTLAGAVSDLLTAVQPSSGE-----------------PRQTVLTAAGSIGQASGELLRQIGENE---ADERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVTEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVHACHSATEDIELL-KQVSAAASVVSQALNDLLQH--VRQFASRGEPIGRYDQATDTIMSVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMDNSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEAAAKQAAAAATQTIAASQNASLSNKNTAAHQQLVQSCKTVADHI-PQLVQGVRSSQAQAEDLSAQLTLIVSSQNFLQPGSKMVASAKAAVPTVTDQAAAMQLSQCAKNLATSLAELRTAAQKAHEACGPMEIDSALNA----VQTLKNELQDAKMAASDRQLKPLPGETLEKCAQDLGSTSKTVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTSDPQAASDMLDSARDVMEGSANLIQEAKQALVAPGDAEIQ----QRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGESSKKLLVDSLP-----PSTKSFQEAQSELNQAAEDLNQSAGEVVHASRGQSGELAAASGKFSQDFDEFLDAGIEMAGQTQNKDDQMQVIGSLKTISMASSKLLLAAKSLSVDSGAPSAK---NLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--ENPNEPASDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVSVASKALCGLTEAAVQAAYLVGISDPNSQAGQQGLV-DPIQFARANQAIQMACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKTLDGDFSEENRNKCSIATSPLISAVENLTAFA-----SNPEFASIPAQISSEGARAQEPILVSAVTMLESSSSLIKTARSLAINPKDPPTWSSLAGHSRIVSDSIKSLITSIRDKAPGQRECDQSIDSINRFIRDIEQASL--ASVSQDLAM----RDDISLEALQEQLTSVVQEIGHLIDPITT--AARGEAAQLGHKVTQLARYFEPLVLAAVGLVSKVLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAFHTHDAIAEAAQLMKEAVDDLMITLNEAASEVGMVGGMVDSIAEAMSKLDEGTPPEPTG-----TFVDYQTTGV-------KYSKAIAVTA--QEMMTKSVTNPEELGGLA-----------SQVTSDYGNL--AVQGRMAAATAEPKEVGFQIKSRIQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITASSAVSGIIADLDTTIMF-----ATAGTLNAENKE----SFADHRENILKTAKALVEDTKLLVSGAASSQEKLAQAAQSSANTITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALGDLIEATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEHIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITTATAKAVAAGNSCRQEDVIATANLSRKAVSEMLTACKQAVYHPDVNADTR--------QRAF--------------------------RYGTECTFAYLEMLEHV-LSILQKPSLET-KQQLSIFSKRIAAAVTELIQTTETMKGTEWVDPQDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPRQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIAANAA--DDGQWSQGLISAARMVAAATSNLCESANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFSKAEEDDVVVKT------KFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLP 2259
BLAST of Talin vs. Ensembl Mouse
Match: Tln1 (talin 1 [Source:MGI Symbol;Acc:MGI:1099832]) HSP 1 Score: 1004.2 bits (2595), Expect = 0.000e+0 Identity = 852/2768 (30.78%), Postives = 1402/2768 (50.65%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYEL-DENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQP--IAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASN------YQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAV---AIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLA-QLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS-----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDTVTD----------------NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFI---GQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + T+VYD CR + +RIP+ +FGLF+SD D + WL+ K + YY L GD + ++ + R L IR +D T KT+ VDDSK++ ++++ IC ++GI+NH+EYSL+ EL +E + T TL++ KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G K K+ +LK+FLPKEYVK KG ++KI ++ S+ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ + N + + H G + + + R G++ P + + Q + Q + + L+ ++AL I +++ ++AA LD + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N L E R V + ++E NG L++AAK L A +LL +++P + E + L++A VG+AS LL I SD + +D L+ AK +A+ + ++K SVA + T+ + Q +I AA +TS L++ KVVA +I P+ Q+QL + + V +V+ + Q E ++ + + + +++++L QH+ ++ A D L+ +E + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA K+V A K + + E QQ L +AA + + A I+++L + LE A +Q A +A Q + ++Q AA +AS Q C E +P ++ + P P+AQ L+ A Q +Q +++ +++A P ++D + L+ +N T+LA+L+ Q+A P + + ++ +Q L + + G+L PLPGET+E + +G+S+KA S KL + N NY G+ +A+++ + L + ARG+AAL S Q V+D ++ +I+ K AS + L + + + ++ V +P +++D + L++ + + + ++ P T + + QS A A NQ +L+ S T L + + + L G+++ + P+ ++ Q+ S LK +S +S+ LL K L S ++ + +A V+DSIN L++ C P Q+ C+++ RQLE ++ L E P PIN+ SY C+ SV E S+ L M I K G+ +F AI S + ++ QA Y +G+ N+ V P + A M+ C S+ ++ AT + S++C + +++P + + + + K VA +T NL+KTI + + EN +A +L V+ L+ A +NP ++ Q GR A I ++ M+E + L++ A AL + + P + +T + +L ++ APGQ E L LR+LD+A++ S + + S +++++ +M +++++ + I P+ + + +++ LG V + Y P++ ++ A + L H + +++ TKT+ E+ L ++ + + L E V + +DL ++ AS G + M+ SI ++ +L E P + T + ++ K I TV + N L D Q K + A E+ +I A + + ++L H +LVT +GA C Y +KE I +V +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+FA +G+ +N E + + A +E I K K LV D + +V + G QE LA A ++V +L VK LG + + E Q +L+NAV+DVA AL D + TK D + LK+S + MV +V L+K+VK++ED +GTRALE + E +R+E + P K + E+ + MTK + +A+ KA+AA + +QED++ AN+ R+AI D++ K + E AP V ++ + +G+ +++ +++ ++ K N K Q+T S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + +D + MV + +I AQ +++ KERELE R K IRQ
Sbjct: 1 MVALSLKISIGNVVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGD---TMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKDEGTGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKG-ERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQY----------NRVGKVEH----GSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPA---ETDYTAVGCAVTTISSN---LTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEP-----------------RQNLLQAAGNVGQASGELLQQIGE-----SDTDPHFQDVLMQLAKAVASAAA--ALVLKAKSVA-QRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLL-RGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGES------------DLENSRKLLSAAKILADATAKMVEAAKGAAAHPD-SEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASAPKASAGPQPLLVQSCKAVAEQ----IPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSV----VQNLEKDLQEIKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYA--------GI------AARDVAGGLRSLAQAARGVAALTSDP-------AVQAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVD---NALRAVGDASKRLLSDSLP-----PSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPASPNLKSQLAAAARA---VTDSINQLITMCTQQAP-GQKECDNALRQLETVRE--LLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLV-EPTQFARANQAIQMA--CQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRAQCRAATAPLLEAVDNLSAFA-----SNPEFSSVPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPR-EGISQEALHT---QMLTAVQEISHLIEPLAS--AARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMA-LLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAV---AAENEEI-----GAHIKHRVQELGHGCSALVT------KAGALQ------------------CSPSDVYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGT-----LNREGAE----TFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVK------------LGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGD-DPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPA----------------------------KTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLR-------------ACKEAAFHPEVAPDVR--------------LRALHYGRECANGYLELLDHVLLTLQ--KPNPDLKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPRAK-PKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAL---DDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEDQENETVV--VKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2527
BLAST of Talin vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 974.926 bits (2519), Expect = 0.000e+0 Identity = 835/2759 (30.26%), Postives = 1421/2759 (51.50%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG-QGNVNV-QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL+ + + YY L GD +L +K + R IR +D + KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E+A + G Q Q + G K K +LKEFLPKEY+K +G +K+I +++ S+ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F N H G + + + R GS+ P S Q V V Q + + L+ ++ALM I ++ ++ A +DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + D++ +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N ++ Q + S + +Q+ +++ +++ L QH + + +P+ + +E + +++G++ EMV QA++LA+A ++L + + S + + +D + ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ AA + + ++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + A +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I+ + + +A + L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L+ C P Q+ C+++ R+LE +K L E P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L + M++ ++ +++ V +G C+ L++ Y ++E I RS +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+F +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GSN Q +L+NA++DVA AL D TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ I ++A D E V+ +++ +G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ
Sbjct: 5 SLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD---ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF----------NRTGKAEH----GSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---ADTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMSLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAAT-SDSELLKQVSAAASVVSQALHDLLQH--VRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHI-PQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGEASKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLIMLCTQQAP-GQKECDNALRELETVKGML--ENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFA-----SNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVT--AQEMMTKSVTNPEELGGLA-----------SQMTTDYGHL--ALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMF-----ATAGTLNAENGE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDP------------ETQVVLINAIKDVAKALSDLIGATKGAASKPAD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDML--------------------IACKQASFYPD----VSEEVRTRALR---YGTECTLGYLDLLEHV--LVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQ 2527
BLAST of Talin vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 974.926 bits (2519), Expect = 0.000e+0 Identity = 835/2759 (30.26%), Postives = 1421/2759 (51.50%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG-QGNVNV-QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL+ + + YY L GD +L +K + R IR +D + KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E+A + G Q Q + G K K +LKEFLPKEY+K +G +K+I +++ S+ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F N H G + + + R GS+ P S Q V V Q + + L+ ++ALM I ++ ++ A +DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + D++ +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N ++ Q + S + +Q+ +++ +++ L QH + + +P+ + +E + +++G++ EMV QA++LA+A ++L + + S + + +D + ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ AA + + ++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + A +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I+ + + +A + L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L+ C P Q+ C+++ R+LE +K L E P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L + M++ ++ +++ V +G C+ L++ Y ++E I RS +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+F +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GSN Q +L+NA++DVA AL D TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ I ++A D E V+ +++ +G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ
Sbjct: 5 SLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD---ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF----------NRTGKAEH----GSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---ADTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMSLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAAT-SDSELLKQVSAAASVVSQALHDLLQH--VRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHI-PQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGEASKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLIMLCTQQAP-GQKECDNALRELETVKGML--ENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFA-----SNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVT--AQEMMTKSVTNPEELGGLA-----------SQMTTDYGHL--ALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMF-----ATAGTLNAENGE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDP------------ETQVVLINAIKDVAKALSDLIGATKGAASKPAD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDML--------------------IACKQASFYPD----VSEEVRTRALR---YGTECTLGYLDLLEHV--LVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQ 2527
BLAST of Talin vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 974.541 bits (2518), Expect = 0.000e+0 Identity = 835/2759 (30.26%), Postives = 1421/2759 (51.50%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG-QGNVNV-QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL+ + + YY L GD +L +K + R IR +D + KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E+A + G Q Q + G K K +LKEFLPKEY+K +G +K+I +++ S+ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F N H G + + + R GS+ P S Q V V Q + + L+ ++ALM I ++ ++ A +DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + D++ +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N ++ Q + S + +Q+ +++ +++ L QH + + +P+ + +E + +++G++ EMV QA++LA+A ++L + + S + + +D + ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ AA + + ++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + A +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I+ + + +A + L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L+ C P Q+ C+++ R+LE +K L E P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L + M++ ++ +++ V +G C+ L++ Y ++E I RS +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+F +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GSN Q +L+NA++DVA AL D TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ I ++A D E V+ +++ +G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ
Sbjct: 7 SLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD---ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF----------NRTGKAEH----GSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---ADTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMSLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAAT-SDSELLKQVSAAASVVSQALHDLLQH--VRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHI-PQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGEASKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLIMLCTQQAP-GQKECDNALRELETVKGML--ENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFA-----SNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVT--AQEMMTKSVTNPEELGGLA-----------SQMTTDYGHL--ALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMF-----ATAGTLNAENGE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDP------------ETQVVLINAIKDVAKALSDLIGATKGAASKPAD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDML--------------------IACKQASFYPD----VSEEVRTRALR---YGTECTLGYLDLLEHV--LVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQ 2529
BLAST of Talin vs. Ensembl Mouse
Match: Tln2 (talin 2 [Source:MGI Symbol;Acc:MGI:1917799]) HSP 1 Score: 433.721 bits (1114), Expect = 7.623e-125 Identity = 442/1560 (28.33%), Postives = 757/1560 (48.53%), Query Frame = 3
Query: 3633 SAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+A+E ++++ L + ARG+AA + ++ + + DV++ +I+ + + +A + L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L+ C P Q+ C+++ R+LE +K L E P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L + M++ ++ +++ V +G C+ L++ Y ++E I RS +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+FA +G+ +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GSN Q +L+NA++DVA AL D TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ I ++A D E V+ +++ +G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ
Sbjct: 32 AARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGEASKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLIMLCTQQAP-GQKECDNALRELETVKGML--ENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFA-----SNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVTA--QEMMTKSVTNPEELGGLA-----------SQMTTDYGHL--ALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGT-----LNAENGE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDP------------ETQVVLINAIKDVAKALSDLIGATKGAASKPAD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDML--------------------IACKQASFYPD----VSEEVRTRALR---YGTECTLGYLDLLEHV--LVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQ 1437
BLAST of Talin vs. UniProt/SwissProt
Match: sp|Q9Y490|TLN1_HUMAN (Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3) HSP 1 Score: 1010.36 bits (2611), Expect = 0.000e+0 Identity = 852/2769 (30.77%), Postives = 1407/2769 (50.81%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMK-TMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQP--IAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASN------YQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVI--QGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLA-QLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS-----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDTVTD----------------NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVT--GVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFI---GQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + T+VYD CR + +RIP+ +FGLF+SD D + WL+ K + YY L GD + ++ + R L IR +D T KT+ VDDSK++ ++++ IC ++GI+NH+EYSL+ EL E ++ + T TL++ KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G K K+ +LK+FLPKEYVK KG ++KI ++ S+ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ + N + + H G + + + R G++ P + + Q + Q + + L+ ++AL I +++ ++AA LD + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N L E R V + ++E +G L++AAK L A +LL +++P + E + L++A VG+AS LL I SD + +D L+ AK +A+ + ++K SVA + T+ + Q +I AA +TS L++ KVVA +I P+ Q+QL + + V +V+ + Q E ++ + + + +++++L QH+ ++ A D L+ +E + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA K+V A K + + E QQ L +AA + + A I+++L + LE A +Q A +A Q + ++Q AA T +AS Q C E +P ++ + P P+AQ L+ A Q +Q +++ +++A P ++D + L+ +N T+LA+L+ Q+A P + + ++ +Q L + + G+L PLPGET+E + +G+S+KA S +L + N NY G+ +A+++ + L + ARG+AAL S + + DV+D +I + G + R + ++ K++ + ++ V +P +++D + L++ + + + ++ P T + + QS A A NQ +L+ S T L + + + L G+++ + P+ ++ Q+ S LK +S +S+ LL K L + ++ L AA V+DSIN L++ C P Q+ C+++ R+LE ++ L E P PIN+ SY C+ SV E S+ L M I K G+ +F AI S + ++ QA Y +G+ N+ V P + A M+ C S+ ++ AT + S++C + +++P + + + + K VA +T NL+KTI + + + EN +A +L V+ L+ A +NP +I Q GR A I ++ M+E + L++ A AL + + P+ + +T + +L ++ APGQ E L LR+LD+A++ S + + S +++++ +M +++++ + I P+ N + +++ LG V + Y P++ ++ A + L H + +++ TKT+ E+ L ++ + + L E V + +DL ++ AS G + M+ SI ++ +L E P + T + ++ K I TV + N L D RL E+ A E+ +I S + + ++L H +LVT G +Q S A Y +KE I +V +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+F +N E + + A +E I K K LV D + +V + G QE LA A ++V +L VK LG + + E Q +L+NAV+DVA AL D + TK D + LK+S + MV +V L+K+VK++ED +GTRALE + E +R+E + P K + E+ + MTK + +A+ KA+AA + +QED++ AN+ R+AI D++ KE P E AP V ++ + +G+ +++ +++ ++ K + K Q+T S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + ++ + MV + +I AQ +++ KERELE R K IRQ
Sbjct: 1 MVALSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGD---TMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKG-ERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQY----------NRVGKVEH----GSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGD---PAETDYTAVGCAVTTISSN---LTEMSRGVKLLAALLEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAE-----------------PRQNLLQAAGNVGQASGELLQQIGE-----SDTDPHFQDALMQLAKAVASAAA--ALVLKAKSVA-QRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLL-RGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGES------------DLENSRKLLSAAKILADATAKMVEAAKGAAAHPD-SEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVAEQ----IPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSV----VQNLEKDLQEVKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYA--------GI------AARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQR---LAQVAKAVTQA---LNRCVSCLPGQRDVD---NALRAVGDASKRLLSDSLP-----PSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLK---SQLAAAARAVTDSINQLITMCTQQAP-GQKECDNALRELETVRE--LLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLV-EPTQFARANQAIQMA--CQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFA-----SNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPR-EGISQEALHT---QMLTAVQEISHLIEPLAN--AARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMA-LLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYG--RL-ASEAKPAAVAAENEEIGSH-----IKHRVQELGHGCAALVTKAGALQCSPSDA--------------------------YTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMF-----ATAGTLNREGTE----TFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVK------------LGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGD-DPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPA----------------------------KTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLR--------ACKEAAYHP-----EVAPDV--------------RLRALHYGRECANGYLELLDHVLLTLQ--KPSPELKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPRAK-PKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAL---DDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEEQENETVV--VKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2527
BLAST of Talin vs. UniProt/SwissProt
Match: sp|P26039|TLN1_MOUSE (Talin-1 OS=Mus musculus OX=10090 GN=Tln1 PE=1 SV=2) HSP 1 Score: 1004.2 bits (2595), Expect = 0.000e+0 Identity = 852/2768 (30.78%), Postives = 1402/2768 (50.65%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYEL-DENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQP--IAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITA----HQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASN------YQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAV---AIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLA-QLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS-----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDTVTD----------------NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFI---GQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + T+VYD CR + +RIP+ +FGLF+SD D + WL+ K + YY L GD + ++ + R L IR +D T KT+ VDDSK++ ++++ IC ++GI+NH+EYSL+ EL +E + T TL++ KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G K K+ +LK+FLPKEYVK KG ++KI ++ S+ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ + N + + H G + + + R G++ P + + Q + Q + + L+ ++AL I +++ ++AA LD + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N L E R V + ++E NG L++AAK L A +LL +++P + E + L++A VG+AS LL I SD + +D L+ AK +A+ + ++K SVA + T+ + Q +I AA +TS L++ KVVA +I P+ Q+QL + + V +V+ + Q E ++ + + + +++++L QH+ ++ A D L+ +E + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA K+V A K + + E QQ L +AA + + A I+++L + LE A +Q A +A Q + ++Q AA +AS Q C E +P ++ + P P+AQ L+ A Q +Q +++ +++A P ++D + L+ +N T+LA+L+ Q+A P + + ++ +Q L + + G+L PLPGET+E + +G+S+KA S KL + N NY G+ +A+++ + L + ARG+AAL S Q V+D ++ +I+ K AS + L + + + ++ V +P +++D + L++ + + + ++ P T + + QS A A NQ +L+ S T L + + + L G+++ + P+ ++ Q+ S LK +S +S+ LL K L S ++ + +A V+DSIN L++ C P Q+ C+++ RQLE ++ L E P PIN+ SY C+ SV E S+ L M I K G+ +F AI S + ++ QA Y +G+ N+ V P + A M+ C S+ ++ AT + S++C + +++P + + + + K VA +T NL+KTI + + EN +A +L V+ L+ A +NP ++ Q GR A I ++ M+E + L++ A AL + + P + +T + +L ++ APGQ E L LR+LD+A++ S + + S +++++ +M +++++ + I P+ + + +++ LG V + Y P++ ++ A + L H + +++ TKT+ E+ L ++ + + L E V + +DL ++ AS G + M+ SI ++ +L E P + T + ++ K I TV + N L D Q K + A E+ +I A + + ++L H +LVT +GA C Y +KE I +V +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+FA +G+ +N E + + A +E I K K LV D + +V + G QE LA A ++V +L VK LG + + E Q +L+NAV+DVA AL D + TK D + LK+S + MV +V L+K+VK++ED +GTRALE + E +R+E + P K + E+ + MTK + +A+ KA+AA + +QED++ AN+ R+AI D++ K + E AP V ++ + +G+ +++ +++ ++ K N K Q+T S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + +D + MV + +I AQ +++ KERELE R K IRQ
Sbjct: 1 MVALSLKISIGNVVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGD---TMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKDEGTGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKG-ERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQY----------NRVGKVEH----GSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPA---ETDYTAVGCAVTTISSN---LTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEP-----------------RQNLLQAAGNVGQASGELLQQIGE-----SDTDPHFQDVLMQLAKAVASAAA--ALVLKAKSVA-QRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLL-RGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGES------------DLENSRKLLSAAKILADATAKMVEAAKGAAAHPD-SEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASAPKASAGPQPLLVQSCKAVAEQ----IPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSV----VQNLEKDLQEIKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYA--------GI------AARDVAGGLRSLAQAARGVAALTSDP-------AVQAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVD---NALRAVGDASKRLLSDSLP-----PSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPASPNLKSQLAAAARA---VTDSINQLITMCTQQAP-GQKECDNALRQLETVRE--LLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLV-EPTQFARANQAIQMA--CQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRAQCRAATAPLLEAVDNLSAFA-----SNPEFSSVPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPR-EGISQEALHT---QMLTAVQEISHLIEPLAS--AARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMA-LLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGDPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASQAKPAAV---AAENEEI-----GAHIKHRVQELGHGCSALVT------KAGALQ------------------CSPSDVYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGT-----LNREGAE----TFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVK------------LGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGD-DPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPA----------------------------KTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLR-------------ACKEAAFHPEVAPDVR--------------LRALHYGRECANGYLELLDHVLLTLQ--KPNPDLKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPRAK-PKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAL---DDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEDQENETVV--VKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2527
BLAST of Talin vs. UniProt/SwissProt
Match: sp|P54939|TLN1_CHICK (Talin-1 OS=Gallus gallus OX=9031 GN=TLN1 PE=1 SV=2) HSP 1 Score: 998.808 bits (2581), Expect = 0.000e+0 Identity = 854/2779 (30.73%), Postives = 1414/2779 (50.88%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNF--IDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG---QGNVNV---QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKL----KQHLIINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVI--QGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRE-----LATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLS-----TTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGE--DKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVR---SRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLA--SRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
M L + I N +++ + T+VYD CR + +R+P+ + +FGLF+SD D + WL+ K + YY L GD + +K + R L IR +D T KT+ VDDSK++ +++ IC ++GI+N++EYSL+ E ++E + T TLK+ KT +RD K+EK+KQKL TDDELNWL HG+TLR+ GID+ + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G K K LK+FLPKEY+K KG ++KI ++ S+ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ F + K L G + + + R G+ P + ++G Q + + Q + + L+ ++AL I +++ + AA LD + LG D +S+ +RK +D +K + ++T T +++ + D + DY + A+ TI N ++ + ++ + + ++E NG L++AAK L +A DLL ++P + E + L++A VG+ S LL I SD + + +D L+ AK +A+ + ++K +VA K T+ + Q +I AA +TS L++ KVVA +I P+ Q+QL + + V S + ++ + ++ +Q+ + ++++ L KQH D L+ +E + +++G++ EMV QA+ILA+A ++L + + + + D + R+L+ AA+ L DA K+V A K + + E QQ L +AA + + A I+++L LE A +Q A +A Q + ++Q AA + + A+ Q+ + + + + P ++ + P P+AQ L+ A Q +Q +++ +++A P + D + L+ +N +LA+L+ Q+A P + + G +Q+L + A + G+L PLPGET+E + +G+S+KA + L + N NY G+ +A+E+ +++ L + ARG+AA S + + E DV+D +I + G + R V ++ K++ + ++ V +P +++D + + + K ++++ +NKT + QS+ A A NQ+ +L+ S T L + + + + L G+++ + P +Q Q+ S LKS+S +S+ LL K L A S ++ L AA V+DSIN L++ C P Q+ C+++ R+LE +K L E P+ +N+ SY C+ SV E S+ L M I K +F +I S + + ++ QA Y +G+ N+ V +P Q A + I MA N + C + AT + S++C + + +++P + + + K VA +T NL+KTI + + + EN E +A ++ V+ LT A +NP T+ Q GR+A I ++ M+E S L++ A +L + K P + +T + +L ++ APGQRE E + L + +R +D+A++ S + + S +++++ +M +++++ N I P+ + + +++ LG V + Y P+ ++ A P+ + + +++ TKT+ E+ L M+ + + L E V +K +DL ++ AS G + M+ SI ++ +L E P+ + +Q+ T+ + ++V + K +T N D + N +L +DY L Q A ++ E +K+ V +G C L+ Y +KE I R +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+F +N EN + + A +E I K K+LV D + +V + QE LA A ++V +L VK A ++GS E Q +L+NAV+DVA AL D TK D + LK+S + MV +V L+K+VK++ED +GTRALE ++E +R+E + +P + + + E+ + MTK + +A+ KA+AA + +QED++ AN+ R+AI D++ KE P + +D +R + KE + D Y L + V + +H+++ LA S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + QD + MV + +I AQ +++ KERELE R K IRQ P
Sbjct: 1 MVALSLKISIGNVVKTMQFEPSTMVYDACRMIRERVPEAQMGQPNDFGLFLSDEDPKKGIWLEAGKALDYYMLRNGD---TMEYKKKQRPLKIRMLDGTVKTVMVDDSKTVTDMLTTICARIGITNYDEYSLVREIMEEKKEEVTGTLKKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGIDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGPHNEQKHKPGFLELKDFLPKEYIKQKG-ERKIFMAHKNCGNMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQFNRVGKAEL----------------GSVALPAIMRTGAGGP----ENFQVGTMPQAQMQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVNAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQADAITAGTASVVNLTAGDP---ADTDYTAVGCAVTTISSNLTEMSKGVKLLAAL---MEDEGGNGRQLLQAAKNLASAVSDLLKTAQPASAE-----------------PRQNLLQAAGLVGQTSGELLQQIGE-----SDTDPRFQDMLMQLAKAVASAAA--ALVLKAKNVAQK-TEDSALQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLIEAGKLVAKSAEGCVEASKAATNDDQLL-KQVGVAATAVTQALNDLLQHIKQHATGGQPIGRYDQATDTILNVTENIFSSMGDAGEMVRQARILAQATSDLVNAIK------------ADAEGETDLENSRKLLSAAKILADATAKMVEAAKGAAAHPD-SEEQQQRLREAAEGLRMATNAAAQNAIKKKLVHKLEHAAKQAAASATQTIAAAQHAAASNKNPAAQQQLVQSCKVVADQI-PMLVQGVRGSQSQPDSPSAQLALIAASQNFLQPGGKMVAAAKATVPTITDQASAMQLSQCAKNLAAALAELRTAAQKAQEACGPLEIDSAL----GLVQSLERDLKEAKAAARDGKLKPLPGETMEKCAQDLGNSTKAVTSAIAHLLGEVAQGNENY--------TGI------AAREVAQALRSLSQAARGVAANSSDPQAQNAMLECASDVMDKANNLIEEARKAVAKPGDPDSQQRLV---QVAKAVSQA---LNRCVNCLPGQRDVDAAIRMVGEA----SKRLLSDS--FPPSNKT--FQEAQSQLNRAAAGLNQSANELVQASRGTPQDLAKSSGKFGQDFNEFLQAGVEMASLSPTKEDQAQVVSNLKSISMSSSKLLLAAKALSADPTSPNLK---SQLAAAARAVTDSINQLITMCTQQAP-GQKECDNALRELETVKE--LLENPTQTVNDMSYFSCLDSVMENSKVLGESMAGISQNAKNSKLPEFGESISAASKALCGLTEAAAQAAYLVGVSDPNSQAGQQGLV-DP-----TQFAR--ANQAIQMACQNLVDPACTQSQVLSAATIVAKHTSALCNTCRLASSRTANPVAKRQFVQPAKEVANSTANLVKTIKALDGAFNEENRERCRAATAPLIEAVDNLTAFA-----SNPEFATVPAQISPEGRRAMEPIVTSAKTMLESSAGLIQTARSLAVNPKDPPQWSVLAGHSRTVSDSIKKLITNMRDKAPGQRECDEAIDVLNRCMREVDQASLAAISQQLAPR-EGISQEALHN---QMITAVQEINNLIEPVAS--AARAEASQLGHKVSQMAQYFEPLILAAIGAASKTPNHQQQMNLLDQTKTLAESALQMLYTAKEAGGNPKQAAHTQEALEEAVQMMKEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDE----GPMGEPEGTFVDYQT------TMVKTAKAIAVTVQEMVTKSTT-----NPDELGILAN----------QLTNDYGQLA----QQAKPAALTAENEEIGSHIKRRVQELGHGCAALVTKAGALQCSPSDAYTKKELIESARKVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMF-----ATAGTLNRENSE----TFADHREGILKTAKALVEDTKVLVQNATASQEKLAQAAQSSVSTITRLAEVVKLGAASLGS------------EDPETQVVLINAVKDVAKALGDLIGATKAAAGKAGD-DPAVYQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIRQELAVFSSPVPPAQ----------------------------VSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLR--------ACKEAAYHPE--------VSADVRQRALRFGKECA---------------DGYLELLEHVLVILQKPTHELKQQLAGYSKRVASSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPRAKPKQ-ADESLDFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGVIPANAV---DDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASEEKLISSAKQVAASTAQLLVACKVKADHDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFQDHDETVVV---KEKMVGGIAQIIAAQEEMLRKERELEEARKKLAMIRQQQYKFLP 2532
BLAST of Talin vs. UniProt/SwissProt
Match: sp|Q9Y4G6|TLN2_HUMAN (Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4) HSP 1 Score: 974.156 bits (2517), Expect = 0.000e+0 Identity = 835/2763 (30.22%), Postives = 1420/2763 (51.39%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG-QGNVNV-QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLI-FQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE----HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL+ + + YY L + + +L +K + R IR +D + KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E+A + G Q Q + G K K +LKEFLPKEY+K +G +K+I +++ S+ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F N H G + + + R GS+ P S Q V V Q + + L+ ++ALM I ++ ++ A +DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + D+E +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N ++ Q T S + +Q+ +++ +++ L QH + + +P+ + +E + +++G++ EMV QA++LA+A ++L + + S + + +D + ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ AA + + A+ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + +L PLPGET+E + +GS+SKA +L N + + G+ +A+E ++++ L + ARG+AA + + + + DV++ +I+ + + +A A L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L++ C P Q+ C+++ R+LE +K L + P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+ + Q + E +K DD+M ++ AS G + M+ +I ++ ++L E P T + +Q+ TV S K I+VT ++ TK + E+ L+ ++ DY L M++ ++ +++ V +G C+ L++ Y ++E I R+ +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+F +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GS+ Q +L+NA++DVA AL D + TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ +DV +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ + + P VSD R + + G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LV+ A + D D + + V + +I AQ +++ KERELE R K IRQ P
Sbjct: 5 SLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD-ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF----------NRTGKAEH----GSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---ADTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMSLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAAT-TDSELLKQVSAAASVVSQALHDLLQH--VRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKAVADHI-PQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAVESQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGESSKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELETVKGML--DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATAPLIEAVENLTAFA-----SNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEP-----KGTFVDYQT------TVVKYS--KAIAVT--AQEMMTKSVTNPEELGGLA-----------SQMTSDYGHL--AFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMF-----ATAGTLNAENSE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDP------------ETQVVLINAIKDVAKALSDLISATKGAASKPVD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTVFQS-----KDV-----------------------PEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQ-----------------ASFHPDVSDEVR----------TRALRFGTECTLGYLDLLEHV--LVILQKPTPEFKQQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKF-------VGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLP 2534
BLAST of Talin vs. UniProt/SwissProt
Match: sp|Q71LX4|TLN2_MOUSE (Talin-2 OS=Mus musculus OX=10090 GN=Tln2 PE=1 SV=3) HSP 1 Score: 685.641 bits (1768), Expect = 0.000e+0 Identity = 564/1888 (29.87%), Postives = 992/1888 (52.54%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIG-QGNVNV-QPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLS--LKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV 5675
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL+ + + YY L + + +L +K + R IR +D + KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+DE + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E+A + G Q Q + G K K +LKEFLPKEY+K +G +K+I +++ S+ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+K+ VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K + I L + N H G + + + R GS+ P S Q V V Q + + L+ ++ALM I ++ ++ A +DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + D++ +G +L+ AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV+N ++ Q + S + +Q+ +++ +++ L QH + + +P+ + +E + +++G++ EMV QA++LA+A ++L + + S + + +D + ++L+ AA+ L D+ ++V A K E + QQ L +AA + + A I++++ LE A +Q A A Q + +SQ AA + + ++ Q+ + + + + P+++ + D +AQ L+ + Q +Q +++ S++A P V D + L+ +N TSLA+L+ Q+A P + + N +QTL + + A + A +L PLPGET+E + +GS+SK +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I+ + + +A + L + + ++ V +P +++D LKS E K ++++ P TK + QSE A A NQ+ G+++++ S L + + ++ D L G+++ A+ +Q Q+ LK++S S+ LL K L G+ K L AA V++SIN L+ C P Q+ C+++ R+LE +K L E P+ P+++ SY C++SV E S+ L M I KTGD F + + S + + ++ QA Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S +N + A ++ VE LT A +NP +I Q G QAQ I ++ M+E S L+R A +L + K P + T + L ++ APGQRE + + + +R++++A++ S + +++ D I+ + + QL+ ++++ + I PI + + + LG V + SY P+ ++ +A + + + V++ TKT+ E+ L M+
Sbjct: 5 SLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGD-ILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKRSTI---------LQQQFNRTGKAEH----GSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---ADTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMSLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAAT-SDSELLKQVSAAASVVSQALHDLLQH--VRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHI-PQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNT----VQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQAL----IAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDV---ALKSIGEASKKLLVDSLP-----PSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAP---NAKNLLAAAARAVTESINQLIMLCTQQAP-GQKECDNALRELETVKGML--ENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLV-DPIQFARANQAIQMA--CQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFA-----SNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATR------DDISVEALQEQLTSVVQEIGHLIDPIAT--AARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQML 1779 HSP 2 Score: 276.944 bits (707), Expect = 6.304e-73 Identity = 217/626 (34.66%), Postives = 335/626 (53.51%), Query Frame = 3
Query: 6180 VGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAV 8009
+G C+ L++ Y ++E I RS +++ ++ LQ+ ++GTQ CI AA +V+ ++ADLDT I+FA +G+ +N+EN + + A +E+I K K+LV D + +V + LA A ++ QL VK A ++GSN Q +L+NA++DVA AL D TK + D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP +K S E + MTK + +A+ KA+AA + +QED++ AN+ RKA++D++ I ++A D E V+ +++ +G +D+ E++ V K K Q+ S+R+A ++ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AV
Sbjct: 1835 LGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGT-----LNAENGE----TFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDP------------ETQVVLINAIKDVAKALSDLIGATKGAASKPAD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIP-----------------------------EKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDML--------------------IACKQASFYPD----VSEEVRTRALR---YGTECTLGYLDLLEHV--LVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAV 2375
BLAST of Talin vs. TrEMBL
Match: V4BLR4 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_218488 PE=4 SV=1) HSP 1 Score: 1135.55 bits (2936), Expect = 0.000e+0 Identity = 899/2764 (32.53%), Postives = 1464/2764 (52.97%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGD--IGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHL-----IINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQ-AAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIV---LPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDC--------MLMTGLQLIAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXX--XXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEA---FLAMVQECETLSTTTNNQDLMENVS-SLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNE-TQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRD-VQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHPELF 8237
+L+I +V +N +++ + T+VYD CR + +RI + + EFGLF++D D + WL+ + + YY L + +L L ++ + R L +RT+D KTL+VDDS ++ L++ IC +MGI+NHEEYSL+ EL E+E+ KT+TLKR K+ +D KLE+MK+KL TDD++NWL H KTLR+ GID+ + LLLRRK+FFSDQNVDARDPIQLNLLYVQ ++AI++GTHPV++EEAI GIQCQ + G+ K KS +LKEFLPKEY+K KG +KKI +++K G ++ + KV Y CRSLKTYGITFFLVKEK++ KNKLVPRL+GI+KE V+RVDEKTKE+++ WPLTTVRR+AA+ + F+LDFGDYSD Y +QTTEGE+I+QLI GYIDII+ K+KAKD+L D ++ + M+E+NVAP+KA +I HN + S ++ + +G+ GV G + S Q + N + G + LS+ ++AL+I I + L + AA L+ ++ LG+D +S+ +R+ LD+++ +V L +M AT L+ + ++ D DY + +A+ I N ++ ++R + + +ED NG L+ AA+ L AF DLL A++P G K N L+ A ++GEAS+ ++ + + D++ +DTLL AK +AN + +V +K +VA K T+ Q +I +A ATS L++ KVVA +I P Q+QL +A+ V SV+ +++ Q V+ Q L + ++++ L QH+ + H++ V + ++ +++L +++G++ EMV A++LA+A ++L + Q+ S DSD Q+RL+ AA+ L DA LV A K C + NQQ +++ AA + S + A ++++L K LE A RQ + QL+ SS++A KT R N + ++V +P ++ + + + +AQ L+N+ Q+ IQ +L+ + + P V D S LN +++ T+LA+L+ +A V + + QL L +D S G L PLPGET ES + +G++SK + +L N + +G+ S ++ +++ L RG+AA + N+ DV+D +++ + ++ + + + ++ KS+ + + +P +++D + ++ +S +M P NKT + ++Q++ + NQ D++ + + A + LA N +C + M GL E Q Q+ GLKSVS S+ LL A S S+D N +AA V++SIN L++ C + P Q+ C+++ RQ++ ++ L + P+ P+++ +Y C++SV E S++L M I K D +DFC +++ + S + ++ QA Y +G+ + V Q + +N + ASS + AT + S++C + + +S+P + + + K VA +T NL+K I + + + +N + +A ++ VE+LT A + K I+ + RQAQ I A M++G+ S+L+AA L + K P Q + + K+ + +L + +K SAPGQRE + E++ QV+R LD+A++ S N + ++ S+ + +++ S +++ I + N + + + E LG SY P++ S+ A +S+ + +++LTKTV E+ FL +E T+ ++N + +K DL++ ++ AS G + +MI SI KS A++ E VA + AS D T+ + RL K+ + ++ +D S ++++ + ++ DY LV+ +SS NV D +++ V +G+S +++++ Y QK+ RS +++ ++ LQ+ SRGTQ CI A+++V+ ++ DLDT I+F +N E D+ S A +E I K K+LV D + +V QE LA A AV+ +L VK A ++GS E AQ LL+NAV+DVA AL D + TK N + + +LK S + MV +V L+K+VK++ED RGTRALE+++EA+ +E + D D K S E+L+ TKP+ A+ KA+AA + KQEDI+ A+N+GRKAI DL+H+ + +++ ++ A K L++ VA K ++ + +++ SR++A+++ E+ +SA +K D +DP IAENELL AA+ IE AAKK+A LKPR++ ++ E F+ QI+ A I +AT+ LVK AS +Q+ELV+QG++ + + +E QWS GLISAA++VAAAT +L +SA A+VQG ++LI+++KQVA TA LL+AC+VK+D S QRLQAAG+AVKRATEALV+ A + +D V D S+ T D K +V + I AQ +++ KE+EL R K +R+ P+ +
Sbjct: 5 SLKISVVQSNAVKTMQFEPSTIVYDACRMIRERIAEAQQGNPSEFGLFLADEDPKKGVWLEQGRSLEYYLLRNGDL-LEYRKKHRILKVRTLDGALKTLQVDDSHTVGGLMVTICTRMGITNHEEYSLVRELAEDEKEKTLTLKRDKSIAKDQKKLEEMKKKLHTDDDMNWLDHSKTLREQGIDQNEVLLLRRKFFFSDQNVDARDPIQLNLLYVQSRDAILNGTHPVSLEEAIMFGGIQCQVQFGDHVDSKHKSGFLDLKEFLPKEYLKVKGAEKKIFQEHKKHVGLTEIEAKVKYTHQCRSLKTYGITFFLVKEKLKGKNKLVPRLLGITKESVVRVDEKTKEIMKTWPLTTVRRWAASPNSFTLDFGDYSDTYYSVQTTEGEQISQLIAGYIDIILGKKKAKDHLGIDGDDNSMMLEDNVAPAKATIIQHNTSKVSHASSGNVAIPAVIRDGGQGESQYGV---GSMQSTQYTQVSNQAISGHSAAH---------RLSKAQKALLITIEEGLSSVNAAQSQLEHQADLPTLGSDPASKKWREDALDVSRQKVGSQLSAMNAATAQLVTLTSGNQ---DEIDYTAVGSAVNQISSNLNEFSGDVRMLAAL-----QED-NGNKLMNAARRLAGAFSDLLQAAQP---------------GSKEPRLN--LLAAAGKIGEASQDVMDNVG---ETTEDMDKAYQDTLLALAKAVANATAALV--LKAKTVANK-TEDPGLQNKVISSATQCALATSQLVACTKVVAPTIGHPACQEQLIEAAKLVAKSVEGIVEAAQGACRDDYVL-QDLGGAATQVTKALNDLLQHIKKAAGPTKATEVHEEA-VDQIITTTDKLFSSVGDAHEMVKNARLLAQATSQLVTAIRG------------QAESHPDSDVQKRLLAAAKQLADATANLVEAAKGCASSPNDS--NQQMMLRSAAEELRSATNTAASNALKKKLVKRLENAARQAVSASTQLINSSKQANKTNR--NAASQQQLAAQCQVVDEEIPNLVQSIKGAQRHYDSASAQLGLINSSQEFIQPCSRLMAQANSAAPTVTDQSSVLTLNNNIKAMATALAELRTSAAKAAEACHSLEVDSALD----QLHALDKELDDVQRSAESGNLLPLPGETAESAALQLGATSKTVASSMSQLLTAAAQGNE-------DYVGIAS------RDTANALKVLTSAVRGVAATTNDQQIQRNIIGSAHDVMDKSIRLLEEAKSALENPN-SPENSQRLTQVAKSVATA---LSNCINCLPGQRDVDNAIQQITASSQML------ANPSFPGTNKT--YPEVQTDMNNSAVNLNQAASDIVTA--SRGATSQLATSSNRYSECYQQFVHNGLTMAGLTKDYET---QNQIVGGLKSVSMVSS-----KLLLAAKSVSADPNAPNAKNLLAQAARAVTESINHLINICTVSAP-GQKECDNALRQIQMMRNVL--DNPNEPVSDQTYFDCLESVMERSKALGDAMTGISNHAKRNDIDDFCDSVRNFANSVCGLTEASAQAAYLVGIADPASEPGRPGIVDQSQFSRANQAIQMACQNLTNPASSQQQVLSA---ATVVAKHTSALCNACRVASSKTSNPVAKRHFVQSAKDVANSTANLVKAIKALDQDFTDQNRQKCAEAARPLVEAVEELTTFASSPEFASKPAK-ISPKARQAQEPITHAGKGMIDGASSMLQAAKQLAVNPKDPPTYQMYSHHSKSVSDSIKQLVSSIKESAPGQRECDDGIEKINQVIRQLDQASLAAISQN----LAPQNEKSLKAFQEQLINSAREILEKIDFVRN--AAKREPENLGHLSTTIASYFEPLAYSAIGTASRNLNSKQQMNILDLTKTVAESALQFLYASKEGGGNQKATHAHQPIDNAADDMKDVLIDLLQTMEEAASQTGVVSSMIDSISKSIAKIDE--RVAVGEKAS-----------FVDYQTE--------MVRLAKQIA----RSAQDMTGKSTTDVSELGHLANQMTRDYSQLVSNSRGAVSS-TTNV-DVSHRIQSTVQDLGKSLIEIVQDAGNLQMNPSDTYAQKDLSDHARSISEKVSFILAALQAGSRGTQACINASSTVSGIIGDLDTTIMF-----ATAGTLNPEGDE----SFADHRESILKTAKALVEDTKTLVAGAASNQEQLASAAQQAVKTITRLADVVKFGAGSLGS------------EQPEAQVLLINAVKDVASALSDLISATK-NASGKDAHDPAMHHLKDSAKVMVTNVTSLLKTVKTVEDEAVRGTRALESTVEAINQEIKAY-----DTTDTFGKKA-----------------------SAEDLIRYTKPITAATAKAVAAANSMKQEDIIAASNMGRKAIMDLLHNCKAAAATA-------------------------ETAEIRQRAINAGRMCGTAYKELLEYVH-----VALAKPSQESRQNLSMVSRKVANAVTELIQSAEAIKGQEWVDPDDPT---VIAENELLGAANSIEAAAKKLASLKPRQAARQ-ADENLNFEEQILDAAKCIAAATAALVKSASAAQRELVAQGKVGSTFHRHTLDEDGQWSQGLISAAKMVAAATHSLCESANAMVQGHATEEKLIASAKQVAGSTAQLLMACKVKADPGSVAMQRLQAAGNAVKRATEALVRSAQQAQDYVDDTSV--TVD---KRLVGGIARDIMAQEEVLRKEKELADARKKLALVRRERYKDRPDEY 2537
BLAST of Talin vs. TrEMBL
Match: A0A1S3HJY6 (talin-1 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106155859 PE=4 SV=1) HSP 1 Score: 1113.21 bits (2878), Expect = 0.000e+0 Identity = 876/2762 (31.72%), Postives = 1451/2762 (52.53%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRV----GS-AQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAM---LIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHL---IINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRV-ANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLI-NSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNN--QQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXX--XXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKN------CISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQ-LKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAA----RLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIK-ANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTG-----EEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISE--QNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L++ IV +N +++ + T++YD CR + +RI + ++GLF++D D + WL+ + + YY L + +L L +K + R L +R +D T KTL+VDDS ++ +L++ IC ++G++NH+E+SL+ +L E E+ KT+TL+RG++ RD KL+++K+KL TDDELNWL H K+LR+ G++E + LLLRRK+FFSDQNVDARDP+QLNLLYVQ ++ I++GTHPV EEA+Q GIQCQ + G+ K KS LKEFLPKEY+K KGI+KKI A++ KL G S+ D KV Y LCRSLKTYGITFFLVKEK++ KNKLVPRL+GI+K+ V+RVDEKTKE+++ WPLTTVRR+AA+ + F+LDFGDYSD Y +QTTEGE+I+QLI GYIDII+KK+KAKD+L + +EE+ M+EE+V+P+KA +I H K A G++ + QG+ GS QP + ++ QG+ Q Q++ +S +R L + + ++ + + E+ LG D +S+ +++ LD++K + L +M AT ++ M D+ DY + +A++TI N + +++R M E D G NL++AA+ L AF DLL A++P + E + L+ A +++GEAS ++ + +++ +D LL AK +AN + +V +K VA K + QA+ +I +A ATS L++ KVVA ++ P Q+QL +A+ V SV+ +++ Q + ++ Q+L + ++++ L QH+ Q+ V L A++RL +++G++ EMV QA++LA+A ++L + + Q+ + D Q+RL+ AA+ L DA ++V A K C + QQ L AA + S + A ++++L K LE A +Q A A QL+ +SQ A K+ R AS Q+ + + + + P+++ +P P AQ NL+NA + +IQ +L+ S++A P V D + +L + +N +LA+L+ +A + +A+I D L ++ ++ G+L PLPGET+ES + +G +SK +L N NY G+ +AK+ ++ L RG+AA +N+ + DV+D ++I + + + L + + ++ V +P +++D + ++ S + + + KS S++Q+E + A NQ D++ + T L + ++S+ ++ G+ Q Q+ SGLKSVS S+ LL A S S+D N +AA V+DSIN L+ C ++ P Q+ C+++ RQ++ + L + P+ P+++ SY C+ SV E S++L M I K G +FC +++ + S + ++ QA Y +G+ S + P L+ + N C ++ ++++ AT + S++C + + + +++P + + + K VA +T NL+K I + S +N A + ++ VE+LT A T+ K I+ + R+AQ I + M++G+C +++AA L K P + + K+ + L +K SAPGQ+E + E++ +++LD+A + S + ++ ND+ Q+ +S Q + + I P+ + + + E LG V SYL P+++++ A + +S+ + V++ TKTV E+ L ++ + + + D + + ++K DL++ ++ ++ G + M+ ++ K+ A R+ N++ +D + + + I I + S N + L + + + + A+E S + A++ + K+ V D L ++Q +G G+ K+ DL+ + + V +++ ++ LQ+ +RGTQ CI AA++V+ ++ DLDT I+F +N + D + A +E I K K+LV D + +V QE LA A +AVR +L VK A ++GS E AQ LL+NAV+DVA AL D +CTK N ++ SNLK S +TMV +V L+K+VK++ED RGTRALE+++E + +E R E+ + SD + E+L+ TK + A+ KA+AA + +QEDI++AAN+GRKA+ D++ + K + ++ I RT+ S ++ + E L+D+ +A K +K + AS+++A+++ EI +SA +K T D +DP IAENELL AA+ IE AAKK+A LKPR+ K+ G E F+ QI+ A SI +AT+ LVK A +Q+ELV QG++ + S + QWS GLISAA++VAAAT NL ++A ++VQG ++LIS++KQVA+ TA LL+AC+VK+D DS + QRLQ AG+AVKRATEALV+ A + +++ + T NK MV M +I AQ +I+ KE+ELE R++ IR+ +P
Sbjct: 5 SLKVSIVGSNIVKTMQFEPSTIIYDACRMIRERIQEANQGNPADYGLFLADEDPKKGVWLEQGRTLEYYLLRNGDL-LEYKKKQRILRVRMLDGTVKTLQVDDSHTLGQLMVTICTRIGVTNHDEFSLVRDLSEEEKEKTLTLRRGQSLARDQKKLDELKKKLHTDDELNWLDHSKSLREEGVEENETLLLRRKFFFSDQNVDARDPVQLNLLYVQSRDGILNGTHPVTQEEAVQFGGIQCQIQFGDHNEQKHKSGFLELKEFLPKEYMKIKGIEKKIFAEHRKLIGSSEIDAKVRYCSLCRSLKTYGITFFLVKEKMKGKNKLVPRLLGITKDSVVRVDEKTKEILKTWPLTTVRRWAASPNSFTLDFGDYSDSYYSVQTTEGEQISQLIAGYIDIILKKKKAKDHLGIEGDEESTMLEESVSPAKATIIQHQ--------SSKTGQAVTGNVAMPAVLRAGGQGQAQFSHGSMQQPQYGKIQNQFHQGHAPPAGQNAQMQGMSHAQRGLWSSMNSAITDIETVEGSMHQRAELPPLGPDHASKKWKENALDVSKHHIGSQLSAMNAATAQVVTMT---SGGPDDTDYTAVGSAVSTITANMTEFAKDVR----MLAALQESDEVGDNLLDAARRLAGAFSDLLKAAQPGSSE-----------------PRQNLLTAASKIGEASN---EVMKTAGDGTDEVDKAFQDALLALAKAVANATAALV--LKAKGVASK----CDDQALQNRVISSATQCALATSQLVACTKVVAPTVSNPACQEQLVEAAKLVAKSVEGIVETAQTACKDDRLL-QELGAAATAVTKALNDLLQHIKQGSGGGQGGQQEVAVEAILGATDRLFSSMGDAPEMVRQARVLAQATSQLVNAIKG------------QAEGHSEPDMQKRLLAAAKVLADATARMVEAAKGCASNPNDS-SQQQHLKAAAEDLRSATNKAASNALKKKLIKTLEVAAKQAASAATQLINASQAAEKSNRNPASQNQLNASCKSTADEI-PKLVQGIRGTLHSPDSPTAQLNLINASEDMIQVSSRLVNSAKAATPTVSDQATALSLTNATKNMSAALAELRTAAAKAQEACGTLEIDGALAHIND-----LERELEEIEQTCQAGKLLPLPGETMESSALQLGHTSKTVGSSMAQLLTAAAQGNENY--------TGI------AAKDTANALGVLTNAVRGVAACSDDRKVQQNIIDAARDVMDKSARLIEEAKRAVSSPNSPDNQ----QRLAQVAKAVSHALNNCVNCLPGQRDVDAAIKEISSMSQTISSG--------QFPHTDKSFSEVQNEMSAAANNLNQATTDVVAAAQGTPQQLASASNSYSKSYSELVNEGMTFAGMTKEREVQSQIVSGLKSVSMVSS-----KLLLAAKSLSADPNAPNARNLLSQAARAVTDSINQLIDICTTSAP-GQKECDNALRQIQVMHNVL--DNPTEPVSDASYFDCVDSVMEKSKALGDSMLGITDHAKRGALEEFCGSVKQFAGSVCGLTEAAAQAAYLVGI---------SDRASEPGKPGLVDQSQFSRANQAIQMACETLTDPSSTQQQVLSAATVVAKHTSALCNICRVASSKTTNPVAKRHFVQSAKDVANSTANLVKAIKALDSDFSEQNRKRCADAAKPLIGAVEELTTFASSPEFTSVPAK-ISREARKAQEPIISSGKAMIDGACHMVKAAKQLAAHPKDPPTYLLYSNHSKSVSDAIKSLVAAMKESAPGQKECDDAIEKVTSTIKDLDQAALAAISNSLPAR-----NDNNQQGFQQQMISCAQEIADRIDPVRT--AGKGEAEKLGHLVTNMASYLDPLADAAVGTASKIMNSKRQMAVLDQTKTVAESALQLIYVAKEGAGNPKSNDAHTAIDDAADNMKEVMADLLQTMEEASATAGVVTAMVDNLGKAIAKTDDRIVVHENLSFVDYQTNMVRLAKKIAQIAQDMVGKSSNNPEELGGLGNQLTREYGELASESQGATSCSSTAEIGHQIKRTVQDLGRLCIELVQ--DAGHLQSSPGDSFAKR----------DLVEHARA-----VSEKVSHVLAALQAGARGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLNPDADTEQ---FADHREAILKTAKALVEDTKTLVAGAAANQEQLAGAAQSAVRTITRLTDVVKFGAASLGS------------EQPEAQVLLINAVKDVASALADLISCTK-NAAGKPVQDPSMSNLKDSAKTMVTNVTSLLKTVKTVEDEAARGTRALESTIEGIAQEIRAYES----------------------------SDKSDLKATPEDLIRHTKAISNATAKAVAAGNSGRQEDIIVAANMGRKAVFDIL------VVCKAAAQSAETEEI-----------KHRTLRSGRDCAHNFRE--------LLDLVH-----LAIQKPTYENKQSLGQASKKVANAVTEIVQSAEAIKGTEWVDPDDPT---VIAENELLTAANSIEAAAKKLAALKPRQPAKRADGSQEADESLNFEEQILEAARSIAAATAALVKAAGTAQKELVLQGKVTAAYRASSFLDEDGQWSQGLISAAKMVAAATHNLCEAANSMVQGNASEEKLISSAKQVASSTAQLLVACKVKADTDSVSMQRLQGAGNAVKRATEALVRAAQQAKELSEEEQSLTI---NKRMVGGMAQIIMAQEEIIRKEKELEAARSRLAMIRKEKYKDNP 2551
BLAST of Talin vs. TrEMBL
Match: A0A1S3HMQ0 (talin-1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106155859 PE=4 SV=1) HSP 1 Score: 1112.06 bits (2875), Expect = 0.000e+0 Identity = 875/2757 (31.74%), Postives = 1450/2757 (52.59%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRV----GS-AQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAM---LIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHL---IINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRV-ANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLI-NSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNN--QQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXX--XXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKN------CISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQ-LKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQD----LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAA----RLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIK-ANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISE--QNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L++ IV +N +++ + T++YD CR + +RI + ++GLF++D D + WL+ + + YY L + +L L +K + R L +R +D T KTL+VDDS ++ +L++ IC ++G++NH+E+SL+ +L E E+ KT+TL+RG++ RD KL+++K+KL TDDELNWL H K+LR+ G++E + LLLRRK+FFSDQNVDARDP+QLNLLYVQ ++ I++GTHPV EEA+Q GIQCQ + G+ K KS LKEFLPKEY+K KGI+KKI A++ KL G S+ D KV Y LCRSLKTYGITFFLVKEK++ KNKLVPRL+GI+K+ V+RVDEKTKE+++ WPLTTVRR+AA+ + F+LDFGDYSD Y +QTTEGE+I+QLI GYIDII+KK+KAKD+L + +EE+ M+EE+V+P+KA +I H K A G++ + QG+ GS QP + ++ QG+ Q Q++ +S +R L + + ++ + + E+ LG D +S+ +++ LD++K + L +M AT ++ M D+ DY + +A++TI N + +++R M E D G NL++AA+ L AF DLL A++P + E + L+ A +++GEAS ++ + +++ +D LL AK +AN + +V +K VA K + QA+ +I +A ATS L++ KVVA ++ P Q+QL +A+ V SV+ +++ Q + ++ Q+L + ++++ L QH+ Q+ V L A++RL +++G++ EMV QA++LA+A ++L + + Q+ + D Q+RL+ AA+ L DA ++V A K C + QQ L AA + S + A ++++L K LE A +Q A A QL+ +SQ A K+ R AS Q+ + + + + P+++ +P P AQ NL+NA + +IQ +L+ S++A P V D + +L + +N +LA+L+ +A + +A+I D L ++ ++ G+L PLPGET+ES + +G +SK +L N NY G+ +AK+ ++ L RG+AA +N+ + DV+D ++I + + + L + + ++ V +P +++D + ++ S + + + KS S++Q+E + A NQ D++ + T L + ++S+ ++ G+ Q Q+ SGLKSVS S+ LL A S S+D N +AA V+DSIN L+ C ++ P Q+ C+++ RQ++ + L + P+ P+++ SY C+ SV E S++L M I K G +FC +++ + S + ++ QA Y +G+ S + P L+ + N C ++ ++++ AT + S++C + + + +++P + + + K VA +T NL+K I + S +N A + ++ VE+LT A T+ K I+ + R+AQ I + M++G+C +++AA L K P + + K+ + L +K SAPGQ+E + E++ +++LD+A + S + ++ ND+ Q+ +S Q + + I P+ + + + E LG V SYL P+++++ A + +S+ + V++ TKTV E+ L ++ + + + D + + ++K DL++ ++ ++ G + M+ ++ K+ A R+ N++ +D + + + I I + S N + L + + + + A+E S + A++ + K+ V D L ++Q +G G+ K+ DL+ + + V +++ ++ LQ+ +RGTQ CI AA++V+ ++ DLDT I+F +N + D + A +E I K K+LV D + +V QE LA A +AVR +L VK A ++GS E AQ LL+NAV+DVA AL D +CTK N ++ SNLK S +TMV +V L+K+VK++ED RGTRALE+++E + +E R E+ + SD + E+L+ TK + A+ KA+AA + +QEDI++AAN+GRKA+ D++ + K + ++ I RT+ S ++ + E L+D+ +A K +K + AS+++A+++ EI +SA +K T D +DP IAENELL AA+ IE AAKK+A LKPR+ K+ E F+ QI+ A SI +AT+ LVK A +Q+ELV QG++ + S + QWS GLISAA++VAAAT NL ++A ++VQG ++LIS++KQVA+ TA LL+AC+VK+D DS + QRLQ AG+AVKRATEALV+ A + +++ + T NK MV M +I AQ +I+ KE+ELE R++ IR+ +P
Sbjct: 5 SLKVSIVGSNIVKTMQFEPSTIIYDACRMIRERIQEANQGNPADYGLFLADEDPKKGVWLEQGRTLEYYLLRNGDL-LEYKKKQRILRVRMLDGTVKTLQVDDSHTLGQLMVTICTRIGVTNHDEFSLVRDLSEEEKEKTLTLRRGQSLARDQKKLDELKKKLHTDDELNWLDHSKSLREEGVEENETLLLRRKFFFSDQNVDARDPVQLNLLYVQSRDGILNGTHPVTQEEAVQFGGIQCQIQFGDHNEQKHKSGFLELKEFLPKEYMKIKGIEKKIFAEHRKLIGSSEIDAKVRYCSLCRSLKTYGITFFLVKEKMKGKNKLVPRLLGITKDSVVRVDEKTKEILKTWPLTTVRRWAASPNSFTLDFGDYSDSYYSVQTTEGEQISQLIAGYIDIILKKKKAKDHLGIEGDEESTMLEESVSPAKATIIQHQ--------SSKTGQAVTGNVAMPAVLRAGGQGQAQFSHGSMQQPQYGKIQNQFHQGHAPPAGQNAQMQGMSHAQRGLWSSMNSAITDIETVEGSMHQRAELPPLGPDHASKKWKENALDVSKHHIGSQLSAMNAATAQVVTMT---SGGPDDTDYTAVGSAVSTITANMTEFAKDVR----MLAALQESDEVGDNLLDAARRLAGAFSDLLKAAQPGSSE-----------------PRQNLLTAASKIGEASN---EVMKTAGDGTDEVDKAFQDALLALAKAVANATAALV--LKAKGVASK----CDDQALQNRVISSATQCALATSQLVACTKVVAPTVSNPACQEQLVEAAKLVAKSVEGIVETAQTACKDDRLL-QELGAAATAVTKALNDLLQHIKQGSGGGQGGQQEVAVEAILGATDRLFSSMGDAPEMVRQARVLAQATSQLVNAIKG------------QAEGHSEPDMQKRLLAAAKVLADATARMVEAAKGCASNPNDS-SQQQHLKAAAEDLRSATNKAASNALKKKLIKTLEVAAKQAASAATQLINASQAAEKSNRNPASQNQLNASCKSTADEI-PKLVQGIRGTLHSPDSPTAQLNLINASEDMIQVSSRLVNSAKAATPTVSDQATALSLTNATKNMSAALAELRTAAAKAQEACGTLEIDGALAHIND-----LERELEEIEQTCQAGKLLPLPGETMESSALQLGHTSKTVGSSMAQLLTAAAQGNENY--------TGI------AAKDTANALGVLTNAVRGVAACSDDRKVQQNIIDAARDVMDKSARLIEEAKRAVSSPNSPDNQ----QRLAQVAKAVSHALNNCVNCLPGQRDVDAAIKEISSMSQTISSG--------QFPHTDKSFSEVQNEMSAAANNLNQATTDVVAAAQGTPQQLASASNSYSKSYSELVNEGMTFAGMTKEREVQSQIVSGLKSVSMVSS-----KLLLAAKSLSADPNAPNARNLLSQAARAVTDSINQLIDICTTSAP-GQKECDNALRQIQVMHNVL--DNPTEPVSDASYFDCVDSVMEKSKALGDSMLGITDHAKRGALEEFCGSVKQFAGSVCGLTEAAAQAAYLVGI---------SDRASEPGKPGLVDQSQFSRANQAIQMACETLTDPSSTQQQVLSAATVVAKHTSALCNICRVASSKTTNPVAKRHFVQSAKDVANSTANLVKAIKALDSDFSEQNRKRCADAAKPLIGAVEELTTFASSPEFTSVPAK-ISREARKAQEPIISSGKAMIDGACHMVKAAKQLAAHPKDPPTYLLYSNHSKSVSDAIKSLVAAMKESAPGQKECDDAIEKVTSTIKDLDQAALAAISNSLPAR-----NDNNQQGFQQQMISCAQEIADRIDPVRT--AGKGEAEKLGHLVTNMASYLDPLADAAVGTASKIMNSKRQMAVLDQTKTVAESALQLIYVAKEGAGNPKSNDAHTAIDDAADNMKEVMADLLQTMEEASATAGVVTAMVDNLGKAIAKTDDRIVVHENLSFVDYQTNMVRLAKKIAQIAQDMVGKSSNNPEELGGLGNQLTREYGELASESQGATSCSSTAEIGHQIKRTVQDLGRLCIELVQ--DAGHLQSSPGDSFAKR----------DLVEHARA-----VSEKVSHVLAALQAGARGTQACINAAHTVSGIIGDLDTTIMF-----ATAGTLNPDADTEQ---FADHREAILKTAKALVEDTKTLVAGAAANQEQLAGAAQSAVRTITRLTDVVKFGAASLGS------------EQPEAQVLLINAVKDVASALADLISCTK-NAAGKPVQDPSMSNLKDSAKTMVTNVTSLLKTVKTVEDEAARGTRALESTIEGIAQEIRAYES----------------------------SDKSDLKATPEDLIRHTKAISNATAKAVAAGNSGRQEDIIVAANMGRKAVFDIL------VVCKAAAQSAETEEI-----------KHRTLRSGRDCAHNFRE--------LLDLVH-----LAIQKPTYENKQSLGQASKKVANAVTEIVQSAEAIKGTEWVDPDDPT---VIAENELLTAANSIEAAAKKLAALKPRQP-AKEADESLNFEEQILEAARSIAAATAALVKAAGTAQKELVLQGKVTAAYRASSFLDEDGQWSQGLISAAKMVAAATHNLCEAANSMVQGNASEEKLISSAKQVASSTAQLLVACKVKADTDSVSMQRLQGAGNAVKRATEALVRAAQQAKELSEEEQSLTI---NKRMVGGMAQIIMAQEEIIRKEKELEAARSRLAMIRKEKYKDNP 2545
BLAST of Talin vs. TrEMBL
Match: A0A224Z8Y2 (Talin OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1) HSP 1 Score: 1108.21 bits (2865), Expect = 0.000e+0 Identity = 882/2793 (31.58%), Postives = 1452/2793 (51.99%), Query Frame = 3
Query: 63 IEMHTLRILIVPTNKTI-SLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRA-YWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYEL-DENER--MKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIG--HLPNRGDIGVVSQGRVGSAQPI-----AIRNDSKIGQG----NVNVQPQKFQIRDL-SQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINS-------ITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEI-----VLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIE-----DGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAA----LKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHA---SVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDE-WTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV----QECETLSTTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNS-LNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLV-------HDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGS-NPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDR---SNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMK-LKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIR 8204
+ M +L+I VP NK I +++ + T+VYD CR + ++P +E+GLF++D D ++ WL+N K + YY L GD L ++ ++R L +R +D + KT+ VDDS+ IA L++ IC K+GI+NH+E+SL+ +L DEN+ T+TL+R K + K+E++K+KLKTDD+LNW+ H KTLR+LG+DE + L LRRKYFFSD NVD+RDP+QLNLLYVQ ++AI++ THPV +EEA + AG+QCQ + G+ K K+ +LKEFLPK+Y K KGI+KKI A++ K G S+ D KV Y L RSLKTYG+TFFLVKEK++ KNKLVPRL+G++K+ VMR+DE+TKE+++ WPLTTVRR+AA+ + F+LDFGDYS+ Y +QTTEGE+I+QLI GYIDII+KK+KAKD+L D +E + M+E++V+P+KA ++ H K S +G LP GVV G G P+ A + + GQ + Q+ +R+L S+P+RAL+ +G ++A+ ++L+ +LG+D +S +R+ LD + V + +M AT ++ + + D G AAI TI N ++ ++++ + + D+ED +G L++AA+ L NAF DLL A++P N E + L+ A +RVGEAS +L+ I E +D+E Q D LL AKQ+AN + +V K + + QG Q +I AA ATS L++ AK+VA +I P Q+QL ++++V SVD ++ + ++ L A + ++++L L+I T QD + L A++RL + G++ EMV QA++LA A +L + A + DSD+Q+RL+ AA+ L DA +++ A K C + ENQ L +AA + ++ A +++++ LE A R + A Q + ++Q A N I + + M+ V+P V+ P P A + LL +CQ+LI Q++ +S+ P + +P+ L+ S + ++L+DL+ + +A + + +E D +L +H + +L PLPGE E + +G++SK +L N + +A++ ++++L+ RG+ A K + + E+ +++ +Q + ++ + +LA + KS+ ++ + +P +++D ++ + S + + E N +S+S++Q+ A A N+ G ++ S+ ++A L + + +L G+++ ++ + + Q+ LK+VS S+ LL K + A + + L AA V++SIN L++ C S P Q+ C+S+ R ++ ++ L + P+ P+N+ +Y C+ +V E S+SL M I K G+ F +++ +S + ++++ QA Y +G S SS P L L A + C +++ +S+ AT I SS+C + + +++P + + + K VA AT +L+K I + S N + +A +++ V+ LT A K I+ + R AQ I A +++GSC+++ +A +LV + K PA Q+ + K + RL + +K APGQ+E E ++L +R LDRA+++ S + + + + + + ++M+ S ++ + I P+ + + + E LG V +A YL P+ ++ A HS+ + +++ TKTV E L +V Q + D+ E + + +L++ ++ A+ G + ++ S+ K+ RL E + + +I G+ + + +S + ++S Q T+ +++ ++ ++Q+ + ++ +L H Y SL M++ G +++ V +G++C+ L + Y Q+E RS +++ +M LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++SE + ++ +E+I K K+LV D + +V QE LA+A NAV QL AVK A ++G+ NP AQ LL+NAV+DVA AL D TK A + K D ++LK S + MV +V L+K+V+++ED RGTRALE+++EA+ +E R ++ P Q G E+LV T+P+ LA+ KA+AA + +Q DI++AAN+GRKAI DL + VT L E + SR+ S S +E +++ E L + E + K AEGK+ + SR IA ++ EI +A LK T D DPN IAE ELL AAS IE AA+K+A L+PR+SI K+ E FD I+ A SI +ATS LV+ AS +Q+ELV+ G+L S + QWS GL+SAARLVAAAT +L +SA +VQG+ ++LIS++KQVA+ TA LL+AC+VK++ DS + + LQAAG+AVK+AT+ LV+ A + Q+ N+ MV + I A+ +I+ KERELE + + +R
Sbjct: 10 MAMLSLKI-SVPDNKVIKTIQFEPGTLVYDACRVIRDKVPDSALGDAKEYGLFLTDDDPKKSGCWLENGKALGYYLLKSGD---TLEYRKKLRPLRVRMLDGSVKTVLVDDSQPIANLMVVICTKIGITNHDEFSLVRDLPDENKEPNTGTLTLRREKKEKDRDQKMEQLKKKLKTDDDLNWVDHSKTLRELGVDEDEMLTLRRKYFFSDSNVDSRDPVQLNLLYVQARDAILNTTHPVTLEEACKFAGLQCQIQFGDHNETKHKAGFLDLKEFLPKDYAKIKGIEKKIFAEHRKNIGTSELDAKVKYVALARSLKTYGVTFFLVKEKMKGKNKLVPRLLGVTKDSVMRLDERTKEIMKVWPLTTVRRWAASPNSFTLDFGDYSESYYSVQTTEGEQISQLIAGYIDIILKKKKAKDHLGIDGDEGSTMVEDSVSPAKATILQHT-------PAAKPSQPAVGLVALP-----GVVRPGTKGPQVPVKGHMPAPQQQMETGQAISAHSATTPAQQPHVRELQSEPQRALLGSLGAGRDAVQASLQELEVPQARPQLGSDPASLQWRQSHLDTHRQNVSSQIAAMNAATAQVVTLTAAPPEEMDQPAVG---AAITTIASNLPEMSKDVKMIAAL---MDDED-SGEKLLDAARRLCNAFSDLLRAAEPQNKE-----------------PRQNLLNAASRVGEASHAVLYTIGEEDE--ADMELQ--DQLLAAAKQVANATAALVLQAKNVASTCDD-QGQ--QNRVIGAATQGALATSQLVACAKIVAPTITSPSCQEQLTEASKEVGKSVDAIVASCEEATRQEPLL-SDLRAAAAQVSRALEELL--LLIRGAPERRARATLAQDGALDTILDATDRLFSCTGDAPEMVRQAKVLARATAQLIQAIKGEAQAEP------------DSDQQKRLLAAAKVLADATARMIEAAKGCASNPHDS-ENQAALRKAAEELRHATNVAASNALKRKIIVRLENAARHASSAATQNIAAAQNAGPY----NSNIMLQEELMSSCRDVAGVIPRVVQGIKGTVAEPDSPMAHHKLLTSCQELIPPAGQMVSASKGCVPTIVEPACAVQLSNSTKQMSSALSDLRSALDKAQETCGRQQQEIDSALERIRELDQELVDIH-------RAALANQLRPLPGENSELCALKLGATSKVVGSSMAQLLTAASQGNESYTGT-------------AARDTASALQQLVEAVRGVVASSGEAKRLVEPARQVLERSCQLLEEARQAVLRPDEPDKQQRLAHV--------AKSVSAA---LNACINCLPGQKDVDDVIRTITESSQALNAR--------EFPNSNRSYSELQANLNEAAAELNEATGHMVQSSRGNAAQLASSVRHFGTAFGSLLGCGMEMASQTQDQEVRSQMVVSLKNVSMVSSKLLVAAKSVAADPSAPNAK---NQLAVAARNVTESINHLVNVCTSAAP-GQKECDSAVRAIQMMRPML--DQPNEPVNDLTYYDCLDTVLERSQSLGDAMTGIANHAKHGEHEQFSESVREVSTTICTLVEASAQAAYLVGASDS------SSMAGKPGLVDLSHFARASQAIQMACQQLSNPASSQPQILSAATVIAKHTSSLCNACRVASSKTTNPVAKRHFVQSAKDVASATASLVKEIKVLDQEPSDANRQRCGEATRPLIDAVDSLTTFASSPEFAGVPAK-ISHKARVAQEPILAAGRSIIDGSCNMILSAKSLVLNPKDPPAWQSLGAHSKEVSDGIKRLVSSIKDEAPGQKECDEAIDKLNAAIRELDRASLNILSQESTHQAD---SSLLKTYQEQMESSASEILDIIEPLR--YAAKGEAEKLGHTVNQAVGYLGPLVQNVIAGASHTLHSKRQMALLDQTKTVAEGMLQLVYASKQAAGNPKAVHVHGDVDEAADNTRDALQELLRTLESAATEAGVVTGLVDSVSKAMYRLEERSTI--------------TISGLRSSGSYSSAVEPELSYVDYQ----TRMVRSAKEVARVAQDMVTHASHDPSRLTPLAADLSHHYASLAGDARGAMATSTSVEVPG--RIRAGVQDLGKACISLTKSAGACQSSPGDIYTQRELAENARSVSEKVSHIMAALQAGSRGTQACINAASTVSGIIGDLDTTIMF-----ATAGTLHSEKEGDQ---FVDHRENILKTAKALVEDTKTLVAGAASSQEQLAVAAQNAVSTIVQLAEAVKLGAASLGAHNP-------------EAQVLLVNAVKDVAAALGDLVQATK----AASGKGIDHPAMAHLKDSAKVMVTNVTSLLKTVRAVEDEHARGTRALESTVEAISQEVRAFDSSEPPLR-------QAGP---------------------EDLVRATQPVTLATAKAVAAGNSGQQGDIIVAANMGRKAIFDL---LSVTKSASCLAETQELKSRVLS---------------SGRECAIRYRE-------LLQLVLEVVQKPTAEGKQ------ALVSTSRNIAVAVTEIVAAAEALKGT---DWADPNDPTVIAETELLGAASSIEAAARKLANLQPRRSI-KEADESLNFDEMILEAAKSITAATSALVRAASAAQRELVAAGKLGERLPCSSAD-GQWSEGLVSAARLVAAATHSLVESANWLVQGQASEEKLISSAKQVASSTAQLLVACKVKAEPDSSSMRGLQAAGNAVKQATDHLVR-AAQRSIAQEQEFRLVI---NQRMVGGIAQEIGAREEILRKERELEEAHERLRQLR 2565
BLAST of Talin vs. TrEMBL
Match: A0A131YM95 (Talin OS=Rhipicephalus appendiculatus OX=34631 PE=4 SV=1) HSP 1 Score: 1107.82 bits (2864), Expect = 0.000e+0 Identity = 883/2794 (31.60%), Postives = 1453/2794 (52.00%), Query Frame = 3
Query: 63 IEMHTLRILIVPTNKTI-SLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRA-YWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYEL-DENER--MKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIG--HLPNRGDIGVVSQGRVGSAQPI-----AIRNDSKIGQG----NVNVQPQKFQIRDL-SQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETH-SVIYQQLDETVAMICESIDKLKQHLIINS-------ITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEI-----VLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIE-----DGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAA----LKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSA-LTLLAKQLNESHDCMLMTGLQLIAEVPNNQ--QQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHA---SVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDE-WTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV----QECETLSTTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNS-LNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLV-------HDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGS-NPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDR---SNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMK-LKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIR 8204
+ M +L+I VP NK I +++ + T+VYD CR + ++P +E+GLF++D D ++ WL+N K + YY L GD L ++ ++R L +R +D + KT+ VDDS+ IA L++ IC K+GI+NH+E+SL+ +L DEN+ T+TL+R K + K+E++K+KLKTDD+LNW+ H KTLR+LG+DE + L LRRKYFFSD NVD+RDP+QLNLLYVQ ++AI++ THPV +EEA + AG+QCQ + G+ K K+ +LKEFLPK+Y K KGI+KKI A++ K G S+ D KV Y L RSLKTYG+TFFLVKEK++ KNKLVPRL+G++K+ VMR+DE+TKE+++ WPLTTVRR+AA+ + F+LDFGDYS+ Y +QTTEGE+I+QLI GYIDII+KK+KAKD+L D +E + M+E++V+P+KA ++ H K S +G LP GVV G G P+ A + + GQ + Q+ +R+L S+P+RAL+ +G ++A+ +L+ +LG+D +S ++R+ LD + V + +M AT ++ + + D G AAI TI N ++ ++++ + + D+ED +G L++AA+ L NAF DLL A++P N E + L+ A +RVGEAS +L+ I E +D+E Q D LL AKQ+AN + +V K + + QG Q +I AA ATS L++ AK+VA +I P Q+QL ++++V SVD ++ + TH + L A + ++++L L+I T QD + L A++RL ++ G++ EMV QA++LA A +L + A + DSD+Q+RL+ AA+ L DA +++ A K C + ENQ L +AA + ++ A +++++ LE A R + A Q + ++Q A N I + + M+ V+P V+ P P A + LL +CQ+LI Q++ +S+ P + +P+ L+ S + ++L+DL+ + +A + + +E D +L +H + +L PLPGE E + +G++SK +L N + +A++ ++++L+ RG+ A K + + E+ +++ +Q + ++ + +LA + KS+ ++ + +P +++D ++ + S + + E + +S+S++Q+ A A N+ G ++ S+ ++A L + + +L G+++ + + + Q+ LK+VS S+ LL K + A + + L AA V++SIN L++ C S P Q+ C+S+ R ++ ++ L + P+ P+N+ +Y C+ +V E S+SL M I K G+ F +++ +S + ++++ QA Y +G S SS P L L A + C +++ +S+ AT I SS+C + + +++P + + + K VA AT +L+K I + S N + +A +++ V+ LT A K I+ + R AQ I A +++GSCS++ +A +LV + K PA Q+ + K + RL + +K APGQ+E E ++L +R LDRA+++ S + + + + + + ++M+ S ++ + I P+ + + + E LG V +A YL P+ ++ A HS+ + +++ TKTV E L +V Q + D+ E + + +L++ ++ A+ G + ++ S+ K+ RL E + + +I G+ + + +S + ++S Q T+ +++ ++ ++Q+ + ++ +L H Y SL M++ G +++ V +G++C+ L + Y Q+E RS +++ +M LQ+ SRGTQ CI AA++V+ ++ DLDT I+F ++SE + ++ +E+I K K+LV D + +V QE LA+A NAV QL AVK A ++G+ NP AQ LL+NAV+DVA AL D TK A + K D ++LK S + MV +V L+K+V+++ED RGTRALE+++EA+ +E R ++ P Q G E+LV T+P+ LA+ KA+AA + +Q DI++AAN+GRKAI DL + VT L E + SR+ S S +E +++ E L + E + K AEGK+ + SR IA ++ EI +A LK T D DPN IAE ELL AAS IE AA+K+A L+PR+S+ K+ E FD I+ A SI +ATS LV+ AS +Q+ELV+ G+L S + QWS GL+SAARLVAAAT +L +SA +VQG+ ++LIS++KQVA+ TA LL+AC+VK++ DS + + LQAAG+AVK+AT+ LV+ A + Q+ N+ MV + I A+ +I+ KERELE + + +R
Sbjct: 1 MAMLSLKI-SVPDNKVIKTIQFEPGTLVYDACRVIRDKVPDSALGDAKEYGLFLTDDDPKKSGCWLENGKALGYYLLKSGD---TLEYRKKLRPLRVRMLDGSVKTVLVDDSQPIANLMVVICTKIGITNHDEFSLVRDLPDENKEPNTGTLTLRREKKEKDRDQKMEQLKKKLKTDDDLNWVDHSKTLRELGVDEDEMLTLRRKYFFSDSNVDSRDPVQLNLLYVQARDAILNTTHPVTLEEACKFAGLQCQIQFGDHNETKHKAGFLDLKEFLPKDYAKIKGIEKKIFAEHRKNIGTSELDAKVKYVALARSLKTYGVTFFLVKEKMKGKNKLVPRLLGVTKDSVMRLDERTKEIMKVWPLTTVRRWAASPNSFTLDFGDYSESYYSVQTTEGEQISQLIAGYIDIILKKKKAKDHLGIDGDEGSTMVEDSVSPAKATILQHT-------PAAKPSQPAVGLVALP-----GVVRPGTKGPQVPVKGHMPAPQQQMETGQAISAHSATTPAQQPHVRELQSEPQRALLGSLGAGRDAVQASLRELEVPQARPQLGSDPASLHWRQSHLDTHRQNVSSQIAAMNAATAQVVTLTAAPPEEMDQPAVG---AAITTIASNLPEMSKDVKMIAAL---MDDED-SGEKLLDAARRLCNAFSDLLRAAEPQNKE-----------------PRQNLLNAASRVGEASHAVLYTIGEEDE--ADMELQ--DQLLAAAKQVANATAALVLQAKNVASTCDD-QGQ--QNRVIGAATQGALATSQLVACAKIVAPTITSPSCQEQLTEASKEVGKSVDAIVASCEE--ATHQEPLLSDLRAAAAQVSRALEELL--LLIRGAPERRARATLAQDGALDTILDATDRLFSSTGDAPEMVRQAKVLARATAQLIQAIKGEAQAEP------------DSDQQKRLLAAAKVLADATARMIEAAKGCASNPHDS-ENQAALRKAAEELRHATNVAASNALKRKIIVRLENAARHASSAATQNIAAAQNAGPY----NSNIMLQEELMSSCRDVAGVIPRVVQGIKGTVAEPDSPMAHHKLLTSCQELIPPAGQMVSASKGCVPTIVEPACAVQLSNSTKQMSSALSDLRSALDKAQETCGRQQQEIDSALERIRELDQELVDIH-------RAALANQLRPLPGENSELCALKLGATSKVVGSSMAQLLTAASQGNESYTGT-------------AARDTASALQQLVEAVRGVVASSGEAKRLVEPARQVLERSCQLLEEARQAVLRPDEPDKQQRLAHV--------AKSVSAA---LNACINCLPGQKDVDDVIRTITESSQALNAR--------EFPSSNRSYSELQANLNEAAAELNEATGHMVQSSRGNAAQLASSVRHFGTAFGSLLGCGMEMAGQTQDQEVRSQMVVSLKNVSMVSSKLLVAAKSVAADPSAPNAK---NQLAVAARNVTESINHLVNVCTSAAP-GQKECDSAVRAIQMMRPML--DQPNEPVNDLTYYDCLDTVLERSQSLGDAMTGIANHAKHGEHEQFSESVREVSTTICTLVEASAQAAYLVGASDS------SSMAGKPGLVDLSHFARASQAIQMACQQLSNPASSQPQILSAATVIAKHTSSLCNACRVASSKTTNPVAKRHFVQSAKDVASATASLVKEIKVLDQEPSDANRQRCGEATRPLIDAVDSLTTFASSPEFAGVPAK-ISHKARVAQEPILAAGRSIIDGSCSMILSAKSLVLNPKDPPAWQSLGAHSKEVSDGIKRLVSSIKDEAPGQKECDEAIDKLNAAIRELDRASLNILSQESTHQAD---SSLLKTYQEQMESSASEILDIIEPLR--YAAKGEAEKLGHTVNQAVGYLGPLVQNVIAGASHTLHSKRQMALLDQTKTVAEGMLQLVYASKQAAGNPKAVHVHGDVDEAADNTRDALQELLRTLESAATEAGVVTGLVDSVSKAMYRLEERSTI--------------TISGLRSSGSYSSAVEPELSYVDYQ----TRMVRSAKEVARVAQDMVTHASHDPSRLTPLAADLSHHYASLAGDARGAMATSTSVEVPG--RIRAGVQDLGKACISLTKSAGACQSSPGDIYTQRELAENARSVSEKVSHIMAALQAGSRGTQACINAASTVSGIIGDLDTTIMF-----ATAGTLHSEKEGDQ---FVDHRENILKTAKALVEDTKTLVAGAASSQEQLAVAAQNAVSTIVQLAEAVKLGAASLGAHNP-------------EAQVLLVNAVKDVAAALGDLVQATK----AASGKGIDHPAMAHLKDSAKVMVTNVTSLLKTVRAVEDEHARGTRALESTVEAISQEVRAFDSSEPPLR-------QAGP---------------------EDLVRATQPVTLATAKAVAAGNSGQQGDIIVAANMGRKAIFDL---LSVTKSASCLAETQELKSRVLS---------------SGRECAIRYRE-------LLQLVLEVVQKPTAEGKQ------ALVSTSRNIAVAVTEIVAAAEALKGT---DWADPNDPTVIAETELLGAASSIEAAARKLANLQPRRSV-KEADESLNFDEMILEAAKSITAATSALVRAASAAQRELVAAGKLGERLPCSSAD-GQWSEGLVSAARLVAAATHSLVESANWLVQGQASEEKLISSAKQVASSTAQLLVACKVKAEPDSSSMRGLQAAGNAVKQATDHLVR-AAQRSIAQEQEFRLVI---NQRMVGGIAQEIGAREEILRKERELEEAHERLRQLR 2556
BLAST of Talin vs. Ensembl Cavefish
Match: tln1 (talin 1 [Source:ZFIN;Acc:ZDB-GENE-031002-48]) HSP 1 Score: 964.911 bits (2493), Expect = 0.000e+0 Identity = 848/2772 (30.59%), Postives = 1393/2772 (50.25%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQ--PQKFQ-----------IRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQS-DFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPN--NQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXX--XXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRE-----LATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQD-LMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDA-ASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRS---NLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHR-DVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
M L + I N +++ + T+VYD CR + +R+P+ + ++GLF+SD D + WL+ K + YY L GD L +K + R L IR +D T KT+ VDDSK ++++++ IC ++GI+N++EYSL+ ++ E ++ +T TLKR KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G+ K K +LKEFLPKEY+K KG +KKI ++ ++ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE++Q W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ F +G V G V A P+ +R+ + GQG+ + PQ Q + L+ ++AL I +++ ++AA LD + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N ++ + ++ + + ++E G L+ AA+ L A D+L ++P + E + L++A VG+AS LL I SD + Q +D L+ AK +AN + ++K +VA K T+ + Q +I AA +TS L++ +VVA +I P+ Q+QL + + V SV+ ++ Q ++ +Q+ + +++++L QH I + P+ + L +E + +++G++ EMV QA+ILA+A ++L + + + + D + R+L+ AA+ L DA ++V A K + + E QQ L +AA + + A I++RL LE A +Q A A Q + ++Q AA + + A+ Q+ + + + + P+++ + P P+AQ L+ + Q +Q +++ +++A P + D + L+ +N ++LA+L+ Q+A P + N + G L + A + A G+L PLPGET+E S +GS++KA S +L + N NY GL + D ++ + L + + A + D ++ +K ++I+ K+ + D +LA + L +S++ + P +++D + +++ E K + + P KS + Q+ A A NQ+ +L+ S T L + + + L G+ + + + +Q Q+ + LK++S +S+ LL A + S+D N K L AA V+DSIN L++ C P Q+ C+++ R+LE ++ L E P+ +N+ Y C+ SV E S+ L M I K + +F A+ S + + ++ TQ Y +G+ N+ V +P Q A +K I MA N + C + AT + S++C + + +S+P + + + + K VA +T NL+K+I + + + EN + KA G ++ V+ LT A +NP ++ Q G A I A+ M+E S +++ A +L + K P + +T + +L ++ APGQRE E E L +R +D+A++ S ++ + + S + ++M S++++ + I P+ ++ +S LG V + SY P+ ++ A + +S+ + V++ TKT+ E+ L ++ +E + Q+ L E V +K DDL + A G + M+ +I ++ R+ E V P + T + ++ K I TV + + KK V + TG+ + +GA + KK +LI +K V +++ ++ LQ+ +RGTQ CI AA++V ++ADLDT I+F +N EN + + A +E I K K LV D + +V QE LA A ++V +L VK A ++GS E Q +L+NAV+DVA AL D TK A K D LK+S + MV +V L+K+VK++ED +GTRALE ++E +++E + P K + E + MTK + LA+ KA+AA + +QED++ AN+ R+AI D++H + + P VS+ R + + GK + + E++ V K K Q+ S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ LKPR + K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A + VQG ++LIS++KQVAA TA LL+AC+VK+D DS+T +RLQAAG+AVK+A++ LVK A + + QD MV + +I AQ +++ KERELE R K IRQ P
Sbjct: 1 MVALSLKIGVGNVVKTMQFEPSTMVYDACRIIRERVPEAQLGQPNDYGLFLSDEDPKKGIWLEAGKALDYYMLRNGD---TLDYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVRDIGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEETEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKPGFLDLKEFLPKEYIKNKG-EKKIFQAHKNCQNMTEIEAKVSYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVMQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVMQQQF----------------------NKVGKVETGSV--AMPVIMRSGAG-GQGSFQMGSIPQAKQQITSGQMHTGHMPPLTSAQQALTGTINSSMQAVQAAQASLDDFDALPPLGTDAASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDP---AETDYTAVGCAVTTISSNLTEMSKGVKLLAAL---MEDEGGTGQQLLGAARNLACAVSDMLKTAQPASTE-----------------PRQNLLQAAGNVGQASGELLQQIGE-----SDADQQFQDMLMKLAKAVANAAA--ALVLKAKNVAQK-TEDSAQQNRVIAAATQCALSTSQLVACTRVVAPTISSPVCQEQLIEAGKLVAKSVEGCVEASQGATGDEHLL-KQVGAAATGVTQALNELLQH--IKQYASGGQPIGRHGEATDRILDVTENIFSSMGDAGEMVRQARILAQATSDLVNAIK------------ADAEGETDLENSRKLLSAAKLLADATARMVEAAKGAAANPD-SEEQQQKLREAAEGLRMATNAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQI-PQLVQGVRGSQAQPDSPSAQLALIGSSQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTAAQKAQEACGPLEIDNALTVVRG----LERDIQEAKAAAAEGKLRPLPGETLEKCSQDLGSNTKAVSSAVAQLLSEAAQGNENY--------TGLAARDVAQALRSLAAAARGVAATTEDPQARNAMLDCTGDVMDKSANLIEETKRAVAKPGDPDCQQRLAQVAKALSQALNRSVNCL-----------PGQRDVD---NAIRTVGEASKKLLSDQFPA-----SGKSFQEAQAGLNQAAAGLNQSANELVQASRGTTQDLAKASGKFGKDFSHFLEAGVDMAGQSQSKEDQTQVVTNLKTISMSSS-----KLLLAAKALSTDPNSPNLKNQLAAAARAVTDSINQLITMCTQQAP-GQKECDNALRELETVRGML--ENPTEAVNDLGYFDCIDSVMENSKVLGEAMAGISHNAKNSNLPEFGDAVSSASKALCGLTEAATQGAYLVGVSDPNSHAGQKGLV-DP-----AQFAK--AKQSIQMACQNLVDPACTQSQVLSAATIVAKHTSALCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKALDGAFNQENRQKCKAATGPLIEAVDNLTAFA-----SNPEFASVPAQISPEGLAAMEPIVAAAKTMLESSTGMIQTARSLAVNPKDPPKWSVLAGHSRTVSDSIKKLITNMRDKAPGQRECDEAIEVLNNCIREVDQASLAAI----SQQLTPRDDISHEALHEQMAASVQEISHLIDPV--AIAARSDASQLGHKVSQMASYFEPLIMAAIGTASKILNSQQQMSVLDQTKTLAESALQILYTAKEAGGNPKAAHTQEALEEAVQMMKEAVDDLGGTLTEAAGAAGAVGGMVDTITQAINRM-EDQAVEPEGSFVDYQTTMVKTAKAIAVTVQEM------------------------------------IGSHIKKQVTELGYSCTGL--VTKAGALQCSPNDSITKK----------ELIDSARK-----VSEKVSHVLAALQAGNRGTQACITAASAVAGIIADLDTTIMF-----ATAGTLNRENAE----TFADHREHILKTAKVLVEDTKLLVSGAGASQEKLAQAAQSSVNTITKLADVVKLGAASLGS------------EDPETQVVLINAVKDVAKALGDLIRATK----AAAGKPHDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIKQELAVFSSADP----------------------------PPKTATPEEFIRMTKGITLATAKAVAAGNSCRQEDVIATANLSRRAIADMLHSCKQ-----------------AAYHPEVSNEVR----------TRALRFGKECAHGYLGLLEHV--LVIIQKPTHDLKQQLASFSKRVAGSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLKPR-AKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATNNLCEAANSAVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSQTMKRLQAAGNAVKKASDNLVKAAQKAAFEAQDDQAVMV----KSKMVGGIAQIIAAQEEMLRKERELEEARRKLAQIRQQQYKFLP 2490
BLAST of Talin vs. Ensembl Cavefish
Match: tln2a (talin-2-like [Source:NCBI gene;Acc:103042966]) HSP 1 Score: 761.911 bits (1966), Expect = 0.000e+0 Identity = 677/2430 (27.86%), Postives = 1199/2430 (49.34%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQ-----------IRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKE----TQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVI----------QLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDI----DELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEV--PNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXX----XXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVEN-DEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECE----TLSTTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARL-TETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVT 7184
+L+I + N +++ T VYD CR + +R+P+ + EFGLF+SD D + WL++ + + YY L + + VL ++ + R ++ +D KT+ VDDSK++ EL+L IC+++GI+N++EYS++ E E R + M TL++ +T +RD K+EK+K KL TDDELNWL HG+T R+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + GIQ Q + G K ++ +LKEFLPKEYVK +G +KKI +++ ++ + KV Y +L RSLKTYG++FFLVKEK+++KNKLVPRL+G++KE VMRVDEKTKE++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+K+KD + +EE M+E++V+P K+ ++ + NS + H G + + R S P + NV P Q + LS ++AL+ I +++ ++ DL++ E+ LG+D +S+ + + +D +K + + ++T T +++ + + DY + AI TI N ++ + ++ + + ++E +G +L+ AA+TL A DLLNA +P + E + ++ A +G+AS LL I ++ +D +Q D L+ NL + + K ++ T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV + +L++ + V+ Q L + +A + + + D ++ +E + +++G++ EMV QA++LA+A ++L + S + + +D D ++L+ AA+ L DA ++V A K E + QQ L +AA + A I+++L LE +Q A A Q + ++Q AA + + A++ Q+ + + + + P+++ + P D +A L+ A Q +Q +++ S+++ P V D + L+ +N TSLA+L+ A P + + +QTL + + A + + +L PLPGE++E +GS+SKA +L N + + G+ +A+E ++++ L + E + ++D +++++ E +I K A + E ++++ +M + + V +P +++D LKS E K ++ P +KS + QS+ A NQ+ GD+++ S T S L + + +E D L G+++ ++Q Q+ LK++S +S+ LL A+ S VN + AA V+DSIN L++ C P Q+ C+++ R+LEA+ +L + P+ P+N SY C++SV E S+ L M I CKTGD F + V S + + + Q +Y +G+ N+ V +PI + A M+ C ++A +S AT + S++C + +++P + + + K VA +T L+KTI + S EN D+ A ++ V+ LT + +P I+ +G AQ I Q++ M++ S LL A +LV + K + T + L V+ APGQRE + +++ +R +++A + S N + + + S+ + +++ S++++ + I PI + + + LG V + SY P+S ++ +A + H +++ +++ ++T+ E+ L M+ + T + + E ++ DDLM ++ AS G + M+ SI ++ +L T + T++ + + I T D + K +S E + SQ + DY L + +++ ++ ++K V +G CM L++ ++E + R+ +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+F + +N+END +S A+ +E+I K K+LV D + +V E LA A ++ + QL VK A +IG + Q +L+NAV+DVA AL + + TK + + LK + + MV +V L+K+VK++ED RGTRALE ++E +R+E + + DK + E + MTK + A+ KA+AA + +QED++ AN+ R+ I+D++ +V+
Sbjct: 5 SLKICVRQCNVVKTMQFKPATAVYDACRVIRERVPEAQTGPASEFGLFLSDEDPRKGIWLESGRTLDYYMLRNGD-VLEYRRKQRPQKVKMLDGAVKTVMVDDSKTVGELLLTICSRIGITNYDEYSVVRETGEERRDEGMSTLRKDRTLLRDERKMEKLKAKLHTDDELNWLDHGRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFGGIQTQIQFGPHIEQKHRTGLLDLKEFLPKEYVKQRGAEKKIFQEHKACGEMTEIEAKVKYVKLARSLKTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKKSKDRFGLEGDEEATMLEDSVSPKKSTILQQQY----------NSAGRVEH----GSVALPGVLRTSSVGPETL---------NVGTMPSPQQQITTGQMHLGHMPPLSAAQQALVGTINTSMQTVQQVQADLEEVEELPPLGDDLASKVWIQNKVDESKHEIHSQVGAITAGTASVVNLT---AGGPEETDYTAVGCAITTISSNLSEMSKGVKLLAAL---VEDEVGSGQDLMRAARTLTGAVSDLLNAVEPTSGE-----------------PRQTVLNAAGSIGQASGDLLRQIGEKE---TDERFQ--DVLM-------NLAKAVANAAAMMVLKAKNVAQVSEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLMEAGKLVDRSVQGCVNACLSATDDGELLKAVSAAAGVVTQALADLLAHV-------RNYDSCGEPIGRYDQATDTIMNVTENIFSSMGDAGEMVRQARVLAQATSDLVGAMR------------SDAEAEIDVDNSKKLLAAAKLLADATARMVEAAKGAAAFPENE-DQQQKLREAAEGLRVATSAAAQNAIKKKLITRLEVRAKQAAAAATQAIAAAQNAAASNKNTAAHQQLVQSCKAVADHI-PQLVQGVRGSQGQPEDDSAHLALIIASQNFLQPGSKMVASAKSSVPTVTDQAAAMQLSQCAKNLSTSLAELRTAAHMAHEACGPMEIDSALTA----VQTLRNELQDARTAAVKHQLKPLPGESLEKCGQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALKSL-------GQAARGVAAATADAEAAVLMLDSAREVMQGSEMLISKAKEA-LETPGDTESQQTLAQMARSVSHSLNSCVNCLPGQKDVDL---ALKSIGEASKKLLMETLPPC-----SKSFQEAQSDLNQTAAGLNQSAGDVVHASRGTSSQLADASGKFSEDFDEFLDAGIEMAGHTQRKDDQLQVIGNLKNISMSSSKLLL-------AAKSLSVNPRAANAKSLLATAARSVTDSINQLITMCTQHSP-GQRECDNALRELEAV--IVLLDNPNEPVNGLSYFDCIESVMENSKVLGESMAGISQNCKTGDVPAFGECVGVASKALCGLTEVARQTSYLVGVSDPNSQAGQQGLV-DPIQFARANQAIQMA--CQNLADPGSSPSQVLSAATIVAKHTSALCNACRLASAKTTNPVAKRHFVQSAKEVANSTAILVKTIKALDGDFSAENRDKCRVATAPLIEAVDSLT-VFVSSPEFGSVPAQISREGSAAQEPILQSARSMLDSSIKLLTTARSLVLNPKDPALWSLLAAHSHTVSDSIKSLITAVRDKAPGQRECDSAIDSVRKCIREMEQACLSAVSQN----LPTRQDISLEALQEQLMSSVQEVGHLIDPIST--AAKGEASQLGHTVSQLASYFEPLSRAAVGVASKMMHHQEQMNLLDQSRTLAESALQMLYAAKEGGGNPKVTLTHDAIAEAAQLMREAVDDLMLTLNEAASEVGIVGGMVDSIAEAMGKLGAGTPSETEGSFVDYQTVMVKFSRAIAVTAHD-MIGKSVS-------------SPEELGSLASQ------------VTADYGQL--ALHGRLAAATAEPEEVGVQIKSRVQELGHGCMALVQKAGALQICPSDSITKRELMECARTVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMF-----ASAGTLNTENDS---DSFAEHRENILKTAKALVEDTKNLVSGAATSPEKLARAAQSSAKTITQLTEVVKLGAASIGPDDP------------ETQVVLINAVKDVAKALAELISATKGAAGKAAE-DPSMLQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEAAIECIRQELTVFQ----------------------------CKETPDKCSTPEEFIRMTKGITTATAKAVAAGNSTRQEDVISTANLSRRVISDMLTTCKVS 2224 HSP 2 Score: 73.559 bits (179), Expect = 3.633e-12 Identity = 58/126 (46.03%), Postives = 75/126 (59.52%), Query Frame = 3
Query: 7449 EITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAA 7826
E T +L D H+ DP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ S + +++ QWS GLISA AA
Sbjct: 2244 ECTNGFLELLD-HVLQWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAK-PKEADESLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVG-SIPANAEDDGQWSQGLISAVNPTAA 2366
BLAST of Talin vs. Ensembl Cavefish
Match: tln2b (talin 2b [Source:ZFIN;Acc:ZDB-GENE-130325-1]) HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0 Identity = 609/2144 (28.40%), Postives = 1095/2144 (51.07%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHL----IINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEV--PNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDI 6452
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL++ + + YY L + + +L +K + R I+ +D KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E E + M TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AGIQ Q + G K K +LKEFLPKEY+K +G +K+I ++ ++ + KV Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+GI+KE VMRVDE+TK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD D +EE+ M+EE+V+P K+ ++ F E S+A LP G++ G +G + + Q Q + + LS ++ALM I +++ ++ A DL + + LG D +SR + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + ++E +G NL+ AA+TL A DLL A +P + E + ++ A +G+AS LL Q + + + +D ++ AK +AN + +V +K +VA + + T Q +I AA +TS L++ KVV+ +I P+ Q+QL + + V SV+ ++ E + + +Q++ + +++ L QH+ D ++ +E + ++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + ++Q AA + + AS+ Q+ + + + + P+++ + P D +AQ L+ A Q +Q +++ SS++ P V D + L+ +N T LA+L+ Q+A P + + N +QTL + + A + G+L PLPG+++E + +GS+SKA +L N + + G+ +A+E +++ L + ARG+AA ++ S + + V++ +I + ++ A + L + + ++ V +P +++D L+S E + N+ ++ +KS + Q+E N+T+ + +S T S L + + + ++ D L G+++ ++Q Q+ LK++S S+ LL K L G+++ L AA V++SIN L++ C P Q+ C+++ R+LEA++ L + P+ P+++ SY C++SV E S+ L M I CKTGD F + V S + + ++ QA+Y +G+ N S + +PI + A M+ C S+ +S AT + S++C + + +++P + + + K VA T NL+KTI + S EN E + A ++ VE L+ A +NP +I Q G AQ I +++ M++ S LL A +LV + K P + +T + L ++ APGQRE + + + +R++++A++ +V +S + + + S+ + +++ +++++ + I PI + + + LG V + +Y P+ +S LA + + +++ TKT+ E+ L M+ +E ++ D + + L K DD+M ++ AS G + M+ SI ++ R+ E P + +Q+ T +K I++T A E + + ++ ++ + LV G +Q+ + +F ++ L +C V + +++ ++ LQ+ ++GTQ CI AA+SV+ ++ADLDT I+F + +N+EN++ S A +E+I
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTPVYDACRIIRERVPEAQTGQASDYGLFLSDDDPRKGIWLESGRTLDYYMLRNGD-ILEYKKKQRPQKIKMLDGAIKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQEQGEERKEDGMGTLKKERTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQDHKSCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDERTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLDGDEESTMLEESVSPKKSTILQQQF--NRVGRVEHGSVA----LP-----GIMRSGSIGGPDNFNMGSMPAPQQQITTGQMHRGHMPPLSLAQQALMGTINSSMQAVQQAQADLGEVDNLPPLGQDRASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDP---TDTDYTAVGCAITTISSNLTEMSKGVKLLAAL---MEDEVGSGQNLMCAARTLTGAVSDLLRAVEPASGE-----------------PRQTVLTAAGSIGQASGDLLR-----QMGEGETDERFQDIMMNLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVITAATQCALSTSQLVACTKVVSPTISSPVCQEQLVEAGRLVERSVEGCVKACHAASE-EAELLRQVNGAAGAVSQALSDLLQHVRHYASCGEPIGRYDQATDTIMTVTESIFTSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAHPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKLVNRLEIAAKQAAAAATQTIAAAQNAAASNKNTASHQQLVHSCKAVADHI-PQLVQGMRSSQAQPEDLSAQLTLIIASQSFLQPGSKMVTSSKSAIPTVTDQAAAMQLSQCAKNLATCLAELRTAAQKAHEACGPLEIDSALNA----VQTLKNELQDAKMAAFDGQLKPLPGDSLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALRTLAQAARGVAACTAERQSAAAMLDSASHVMEGSAMLIHEAHQAL----ISPGDAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALRSIGEFY----ANSYLCVQLPPCSKSFQEAQTE-------LNRTV--VHSSRGTSSQLAVASGKFSQDFDEFLDAGIEMAGHTQSKDDQIQVIGNLKNISMASSKLLLAAKSLSVDPGAANAK---NLLAAAARAVTESINQLITLCTQQAP-GQKECDNALRELEAVRGML--DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQHCKTGDVPAFGECVGVASKALCGLTEAAGQASYLVGVSDPN-SQSGHQGLVDPIQFAKANQAIQMA--CQSLVDPASSPSQVLSAATIVAKHTSALCNACRLASSKTANPVARRHFVQSAKEVANTTANLVKTIKALDGDFSDENRERCRVATTPLIEAVENLSTFA-----SNPEFASIPAQISNEGSAAQEPILRSARSMLDSSTQLLETARSLVINPKDPPTWSILAGHSRTVSDSIKSLITAIRDKAPGQRECDHSIDSINKCIRDIEQASL--AAVGQS--LPCRDDISLEAVQEQVTSAVQEIGHLIEPIST--AARGEAAQLGHKVTQLSNYFEPLIVASVGLASKHMDHQQQMNILDQTKTLAESSLQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEGGMVGGMVESIAEAMGRMDEGTPPEP----DGTFVDYQT--------TMVKFSKAIAIT------------AQEMVGLQIKTRVQELGHGCIYLVQK-----AGALQMSPTDSFTKRE----LIECARTVTE-------------------KVSMVLSALQAGNKGTQACITAASSVSGIIADLDTTIMF-----ASAGTLNAENEE----SFADHRENI 1972 HSP 2 Score: 222.631 bits (566), Expect = 2.308e-57 Identity = 181/493 (36.71%), Postives = 267/493 (54.16%), Query Frame = 3
Query: 6774 LKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYEN----LNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE--HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E V SK + ++ + E + MTK + +A+ KA+AA + +QED++ AN+ RKAI D++ + K+ P E V+ K + +G ID+ E+ L K A+ + Q+ + S+++A S+ E+ ++A +K + D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQAAG+AVKRA++ LVK A + +D S+ V + +I AQ +++ KERELE R K IRQ P
Sbjct: 2067 LKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEFIKQELT-----------VFQSK-----------------DTPERSTTPEEFIRMTKGITVATAKAVAAGNSGQQEDVISTANLSRKAIADML--------ITCKQAAYHP----------------EVAEDVRN---KALLYGLECSTGYIDLLEHVLLVLQKPTAD------QRQQLAVLSKKVAGSVTELIQTAEAMKGSEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADESLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAV---DDGQWSQGLISAARMVAAATSNLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVKAAQKAAFDKAEDNSVVV-----KTKFVGGIAQIIAAQEEMLRKERELEEARKKLAHIRQQQYKFLP 2486
BLAST of Talin vs. Ensembl Cavefish
Match: hip1 (huntingtin interacting protein 1 [Source:NCBI gene;Acc:103022424]) HSP 1 Score: 80.1073 bits (196), Expect = 3.214e-14 Identity = 66/237 (27.85%), Postives = 116/237 (48.95%), Query Frame = 3
Query: 7524 IAENELLEAASQIETAAKKIA-LLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALV------KEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGH 8213
+ E E+ ++ +E+AA +I +L +++ DTG + + +I+ +C ++ A LV + Q+++V GR + ++W+ GLISA++ V + D+A VVQGK + L+ S ++AA TA L+ A +VK+D DS RLQ A V +AT +V K E D T D + ++ R + +Q ++ E L+ R + +R+ H
Sbjct: 770 LVEQEMAATSAAVESAAARIEEMLNKSRAV--DTGIKMEVNERILASCTELMQAIKVLVLSSKDLQKDIVEGGRGAATIKEFYAKNSRWTEGLISASKAVGWGATMMVDAADLVVQGKGKFEELMVCSHEIAASTAQLVAASKVKADKDSGNLARLQQASRGVTQATAGVVASTKSGKSQIEETD--------TMDFSSMTLTQIKRQEMDSQVRVLELETWLQKERERLGELRKKH 996
BLAST of Talin vs. Ensembl Cavefish
Match: hip1 (huntingtin interacting protein 1 [Source:NCBI gene;Acc:103022424]) HSP 1 Score: 80.1073 bits (196), Expect = 3.323e-14 Identity = 66/237 (27.85%), Postives = 116/237 (48.95%), Query Frame = 3
Query: 7524 IAENELLEAASQIETAAKKIA-LLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALV------KEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGH 8213
+ E E+ ++ +E+AA +I +L +++ DTG + + +I+ +C ++ A LV + Q+++V GR + ++W+ GLISA++ V + D+A VVQGK + L+ S ++AA TA L+ A +VK+D DS RLQ A V +AT +V K E D T D + ++ R + +Q ++ E L+ R + +R+ H
Sbjct: 804 LVEQEMAATSAAVESAAARIEEMLNKSRAV--DTGIKMEVNERILASCTELMQAIKVLVLSSKDLQKDIVEGGRGAATIKEFYAKNSRWTEGLISASKAVGWGATMMVDAADLVVQGKGKFEELMVCSHEIAASTAQLVAASKVKADKDSGNLARLQQASRGVTQATAGVVASTKSGKSQIEETD--------TMDFSSMTLTQIKRQEMDSQVRVLELETWLQKERERLGELRKKH 1030
BLAST of Talin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003776.1 (pep scaffold:Pmarinus_7.0:GL481036:4073:28398:-1 gene:ENSPMAG00000003436.1 transcript:ENSPMAT00000003776.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 579.326 bits (1492), Expect = 3.061e-174 Identity = 495/1560 (31.73%), Postives = 827/1560 (53.01%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSM-RAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERM-KTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSF-EKNSLATIGHLPN--RGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALK-ETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQ----DPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVID--------CGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHS-ALTLLAKQLNESHDCMLMTGLQLI--AEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNA 4682
+L+I + N +++ + TVVYD CR + +R+P+ ++ L +S S R L S + P +L ++ + R L +R +D T KT VDDSK++ +++L +C ++GI+N+EEYSL+ E+ E + M T TLK+ ++ +RD K+EK+KQKL TDD++NWL HG+TLR+ G+++ + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ E A + AG Q Q + G K K +LKEFLPKEYVK +G +K++ +++K ++ + KV Y + RSLKTYG++FFLVKEK++ KNKLVPRL GI+KE VMRVDE+TKE+IQ WPLTTV+R+AA+ F+LDFGDYSD Y +QTTEGE+IAQLI GYIDII+KK+K+KD + +EE+ M+E++V+P K+ VI N N + E S+A LP RG G S GR P A + I G ++ + + +S ++ALM I +++ ++ A LD+ + LG D++S+ +R+ +D AK + + ++ +T + + + D + DY + A+ TI N L E R V + T+EE +G L++AA+ L++ DLL +P + E +A++ A + VG +S LL I + ++ Q +D L AK +AN +G+V +K +VA K + Q + Q +I AA +TS L++ KVV +++ P+ Q+QL S + V +V+ ++ Q + ++ +Q+ + +++D L QH+ + + H D ++A+E + ++ GN+ EMV QA++LA+A ++L + + A + Q N R+L+ AA+ L DA K+V A K E + E QQ L +AA + ++ A IR++L LE A RQ A A Q + ++ +AA + + A+ Q+ ++ + + V P+++ + P P+AQ L+ A +Q +++ +++A P V D + L +N T LA+L+ Q+A + + ++ +++L + + A + + G+L+PLPGET+E+ + +G++SK ++ N NY G+ +A++ +++++L ARG+AA + + E + E D++D K ++R G D I +LA + L K V +P Q++D + L+S + K + + P S + Q A A N + +L+ ++ S L+ +++ L G+ + A+ +Q Q+ LKS+S +S+ L A + K L AA V+DSIN L++ C P Q C+++ R+LE +K L + PS P+N+ SY +C+ S+ E S+ L M+ + KT + F AI S + + ++ +Q+ Y +G+ N+
Sbjct: 5 SLKICVRHCNVVKTMQFEPSTVVYDACRIIRERVPEAQDGQPPATPLALSSLPSPPRPLHLPISSTATSPP--HPQDLLEYRKKQRPLKVRMLDGTIKTAMVDDSKTVGDMLLAVCARIGITNYEEYSLVREVAEEKAMDGTGTLKKDRSLLRDEKKMEKLKQKLHTDDDMNWLDHGRTLREQGVEDSETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEMACEFAGYQAQIQFGPHNEVKHKPGFLDLKEFLPKEYVKQRGAEKRLFQEHKKCESMTEIEAKVRYVRQARSLKTYGVSFFLVKEKMKGKNKLVPRLFGITKESVMRVDERTKEVIQEWPLTTVKRWAASPKSFTLDFGDYSDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDRFGTEGDEESTMLEDSVSPKKSTVIQTNC---NPMGMAEHGSVA----LPAVMRGIGGPESLGR--GVMPGA---NKVITSGAMH----RGHLPPMSTNQQALMGTITSSMQAVQQAGNSLDEMDALPPLGQDKASKAWRQYKMDQAKHEIHSQVDAINASTASCINLTSGDA---ADTDYTAVGCAVVTISSN---LTEMSRGVRLLAALTEEEGGDGRALLQAARGLIDCISDLLKTVQPSSTE-----------------PRQAVLTAASTVGRSSNNLLKQIGQQ-----GVDQQFQDVLNQLAKAVANAAAGLV--LKAKTVAQKADDQALQNQ--VIAAATQCALSTSQLVACTKVVGPTMDSPVCQEQLMESGKLVARAVEGCVRSSQEATKDDELL-RQVGGAAGAVTQALDALLQHVKLLASGGHGMGRYDCATDTIITATESIFSSTGNAGEMVKQARLLAQATSDLINAIKVDAEAEGDQEN------------SRKLLAAAKYLADATAKMVEAAKGAAANPE-SEEQQQRLQEAAEGLRVATNIAAQNAIRKKLVHRLEVAARQAAAAASQAIAAATQAAASNKNPANQQQLVGCSKNVADHV-PQLVQGWRGSQSQPDSPSAQLALITASHNFLQPGTKMVAAAKASVPTVTDQASSMQLGQCAKNLATCLAELRTAAQKAQDACGTLEIDSALDL----VRSLEAELQEAKVAASDGKLHPLPGETLETCAQDLGATSKTVGSSMAQVMTAASQGNENY--------TGI------AARDTAQALKQLAAAARGLAANSADKPTQEAVLESARDLMDKASLFIQEAKKAVVRPG-DPINQQRLAQVAKAVSGALGK-----------CVGCLPGQQDVD---TALRSLADHSKKLLSDTIP-----RSGSSFQEAQGNLNDAAAGLNLSASELVQASRGSSQELSTASRKFGNDFSRFLDAGIDMAGQAKTKEDQVQVVGNLKSISMSSS---KLLLAAKALCVDPNAPNAKNQLAAAARAVTDSINQLITMCTQQAP-GQNECDNALRELETVKGML--DNPSEPVNDLSYFECIDSLMENSKVLGEAMQGVSQNAKTSNLPAFGEAISSASKALCGLTEAASQSAYLVGVSDPNS 1455
BLAST of Talin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007752.1 (pep scaffold:Pmarinus_7.0:GL478287:501:47681:-1 gene:ENSPMAG00000006982.1 transcript:ENSPMAT00000007752.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 318.931 bits (816), Expect = 4.891e-90 Identity = 324/1210 (26.78%), Postives = 570/1210 (47.11%), Query Frame = 3
Query: 951 VKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQ--NSISDLEWQ-------TRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHL--IINSITAHQDP------LVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIV---LPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQ------LQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSD----------------------NSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQL--IAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLE 4427
K Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+G++KE V+RVDE+TKE++Q WPLTTV+R+AA+ F+LDFGDY Y +QTTEGE+I+QLI GYIDII+KK++AKD + +EE+ M+EE+V+P K+ ++ + + +L I P G V+ G + AQ Q + Q K + LS ++AL+ I +++ ++ A DL + LG+D S+++R+ +D +K + + ++T T +++ + D + DY + A+ TI N ++ + +R + + D+E NG +L++AA+ L +A DLL P E ++++ A VG+AS LL I ++ S D+ Q TL+ AK +A + + Q +I AA +TS L++ KVV +I P Q+QL + + V +V+ +Q Q E ++ +Q+ E + ++++ L +H+ S+T P L+A+E + ++G++ EMV QA++LA+A ++L + + A + Q N+ R L+ AA+ L DA ++V A K E E QQ L +AA + ++ A I+++L+ LE A +Q A + Q + ++Q AA + ++ N Q + + ++V +P+++ + + + P AQ +L+ + +Q L+ S+ A P V++ + + L +N L++L+ +A PT +GQ ++ L + ++ A VA+G L PLPGET+ES S +GS+SK +L + +D N+ + + Q + +A+++M+ LL+ AR AA S D+ + L + V + + LA ++ V +P +++D + + + + + +S+ + QS T A A NQ G +++ S+ + L + + L G+++ + + +Q Q+ LK++S +S+ LL K ++ + +V L AA V+DSIN L+S C P Q+ C+++ RQLE
Sbjct: 14 AKSKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGVTKESVLRVDERTKEVMQEWPLTTVKRWAASPKSFTLDFGDYQVGYYSVQTTEGEQISQLIAGYIDIILKKKQAKDRFGLEGDEESTMLEESVSPKKSTILQQQYNRVGKVEHASVALPAIMR-PGAGGPDTVNWGMMPVAQ-----------QQVTSGQMHKGHMPPLSSAQQALVGTITSSMQAVQQAHGDLGDMDSLPPLGDDAESQSWRRNKMDESKHEIHSQVDAITAHTASVVNLTAGDP---ADTDYTAVGCAVTTISSNLTEMSKGVRLLAAL---LDDEGANGQDLMQAARGLASAVSDLLKTVDPSTAE-----------------PRQSVLTAAGNVGQASGELLRTIGEDEADQSFQDMLMQLAKAVANAAATLVLKAKNVA-----------------QRAEDPAQQNRVIAAATQCALSTSQLVACTKVVGPTIRSPACQEQLMEAGKLVARAVEGCVQASQDATEEEELL-RQVGEAATAVTQALNDLLRHVRQYAASLTGRAGPGGSYVQATDTILTATENIFGSMGDAGEMVRQARLLAQATSDLVNAIKADAEAEQDQENV------------RNLLAAARVLADATARMVEAAKGAAANPENE-EQQQKLREAAEGLRVATNIAAQNAIKKKLTNRLEQAAKQAAAASTQTIAAAQHAASSNKSPNSQ--QQLVQSCKVVADHIPQLVQSVRESQSTPDSQQAQQSLITSSLGFLQPGNHLVASARAAVPSVENQASSNQLGTCAKNLAACLSELRAAAHKAQQACSPT---------EGQDSALALVRALENELEEAKTEVAQGRLKPLPGETLESCSLELGSASKTVGSAIAQLLTAASQGDESFTDHAAHEAAEALRGLAAAARGVAANTADPLA-QEAALETARDVMDKSANLLQEARKAAANPSDPDNQQRLAQ------------------VAKAVSLA--------------------LNNCVNSLPGQKDVDSALRNINDASKRLQADSF--------PQSGRSYHEAQSGLTQAAAGLNQATGRVVHASHGSSRELATASGRFGRDFSDFLDAGIEMAGLTQTKEDQVQVIGNLKNISVSSSKLLMAAKSMVIDPAAPNVK---NQLASAARAVTDSINLLISMCTQQAP-GQRECDNALRQLE 1095
BLAST of Talin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010194.1 (pep scaffold:Pmarinus_7.0:GL480176:295:15370:1 gene:ENSPMAG00000009228.1 transcript:ENSPMAT00000010194.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 311.997 bits (798), Expect = 1.413e-89 Identity = 290/958 (30.27%), Postives = 466/958 (48.64%), Query Frame = 3
Query: 5454 SLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETL----------STTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAP-LDAASAHTLIFQSIKGITDTVTD------------NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKE---NSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRL--KPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPN----KSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+++Q+ N I P+ + ++ LG V + SY P+ ++ +A + + +++ TKT+ E+ L ++ + + N + ++ S + + DDL ++ AS G + M+ +I ++ ++ E AP T + ++ K I T + SL ++ + + A+ DN+ +V + K V D + V+ + +GA +C G + DLI +K V +++ ++ LQ+ +RGTQ CI AA++V+ +VADLDT I+FA +G+ +++EN++ S A +E I K K+LV D + +V QE LA A ++V +L VK LG + + E Q +L+NAV+DVA AL D + TK D + NLK + + MV +V L+K+VK++ED +GTRALE ++E +++E E P K S E+ + MTK + LA+ KA+AA + +QED++ AN+ RKA+++++ K+ P + SD R++ KE ++EH + L K A+ +K Q+T S+R+A S+ E+ +SA +K + D EDP IAE ELL AA IE AAKK+ LKPR ++ E F+ QI+ A +I +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+ DS+ +RLQ AG+AVKRA+E LVK A + + + + N + V + +I AQ +++ KEREL+ R K IRQ P
Sbjct: 10 TVQQISNTIDPVATVARGEAS--QLGHKVSQMASYFDPLVFAAVGMASKSLSHQQQMNLLDQTKTLAESALQLLYAAKEAGGNPKSSARPAQALNAHEAIQEASQMMREAVDDLTATLNETASELGMVSGMVDAISQAIGKMDEGTPPAPEYSFVDYQTTMVKTAKAIAVTAQEMVSKSASRPEDLGSLASQLTTEYGNLAQQGRPAAASADNE--------EVGHQIKHRVQDLGH--SCVLLVQKAGAL----------QCSPTDGFTKRDLIDCARK-----VSEKVSMVLASLQAGNRGTQACITAASTVSGIVADLDTTIMFATAGT-----LHAENNE----SFADHREGILKTAKALVEDTKLLVAGAGATQEKLAQAAQSSVGTITRLADVVK------------LGAASLGSEDPETQVVLINAVKDVAKALGDLISATKSAAGKQPD-DPAMHNLKGAAKIMVTNVTSLLKTVKAVEDEATKGTRALEATIECIKQEVMMFETREP----------------------------PQKTASPEDFIRMTKGITLATAKAVAAGNSCRQEDVIATANLSRKAVSEML--------AACKQAAFHPE--------VASDVRARSLRYGKECANGYQALLEH----------VLLVLQKPTAD------NKHQLTNLSKRVAGSVSELIQSAEAMKGSEWVDPEDPT---VIAEAELLGAAPAIEAAAKKLEQLKPRAKPRQ-ADESLNFEEQILEAAKAIAAATSALVKSASAAQRELVAQGKVGASPANAV---DDGQWSQGLISAARMVAAATSNLCEAANAAVQGHASEEKLISSAKQVAASTAQLLVACKVKAAPDSEAMRRLQGAGNAVKRASENLVKAAQK-------AAAFDQEEENVVVKEKFVGGIAQIIAAQEEMLRKERELDEARRKLAQIRQQQYKFLP 844
BLAST of Talin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007037.1 (pep scaffold:Pmarinus_7.0:GL476737:73889:120616:-1 gene:ENSPMAG00000006357.1 transcript:ENSPMAT00000007037.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 221.09 bits (562), Expect = 1.000e-65 Identity = 107/210 (50.95%), Postives = 156/210 (74.29%), Query Frame = 3
Query: 303 VLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENER-------MKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKII 911
+L +K ++R L +R +D KT+ VDDSK++ +L++ IC ++GI+N++EYSLI+E ER +++ TLK+ +T +RD K+EK+KQKL TDDELNW+ HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++ +HPV+ ++A + AGIQ Q + G K K+ +LKEFLPKEYVK KG +KKI
Sbjct: 2 LLEYKRKVRPLKVRMLDGMIKTVMVDDSKTVGDLLITICTRIGITNYDEYSLIWEGGGEERKEDGGGTLRSGTLKKDRTLLRDEKKMEKLKQKLHTDDELNWVDHGRTLREQGVEENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNSSHPVSYDKACEFAGIQAQIQFGPHVEHKHKAGFLDLKEFLPKEYVKQKGSEKKIF 211
BLAST of Talin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002539.1 (pep scaffold:Pmarinus_7.0:GL478866:18799:39338:-1 gene:ENSPMAG00000002312.1 transcript:ENSPMAT00000002539.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 160.614 bits (405), Expect = 3.604e-41 Identity = 151/476 (31.72%), Postives = 239/476 (50.21%), Query Frame = 3
Query: 6210 YDQKEFIGQVRSRLTDLMYL----LQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYEN----LNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIK 7613
+ ++E + R R+T+ + L LQ+ +RGTQ CI A ++V+ ++ADLDT I+FA +G+ +N+E ++ S A +E+I K K+LV D + +V QE LA A ++V L AVK A ++GS+ Q +L+NAV+DVA AL + + TK +D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E E+ N + V AS+ E + MTK + LA+ KA+AA + +QEDI+ AN+ RKAI+D++ + + P VS E V+ +++ G+ +++ E+ L + AE K+Q+ S+R+A+S+ E+ ++A +K T D EDP IAE ELL AA+ IE AAKK+ LKPR K
Sbjct: 159 FAKRELVESAR-RVTEKVSLVLAALQAGNRGTQACITAGSAVSGIIADLDTTIMFASAGT-----LNAEGEE----SFADHRENILKTAKALVEDTKMLVAGAGASQEKLAQAAQSSVATITDLAEAVKLGAASLGSHDP------------ETQVVLINAVKDVAKALAELISATKSAAGKPSD-DASMHQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTVFES---------NDR--------------PVAASTP-----EEFIRMTKGITLATAKAVAAGNSCRQEDIIATANLSRKAISDMLSSCK-----------------RAAYHPDVS-------EDVRSRALRF---GRECTVGYLELLEHVLVILQRPTAE------LKLQLAAFSKRVANSVTELIQAAEAMKGTEWVDPEDPT---VIAEAELLGAAAAIEAAAKKLEQLKPRAKPK 547
BLAST of Talin vs. Ensembl Yeast
Match: SLA2 (Adaptor protein that links actin to clathrin and endocytosis; involved in membrane cytoskeleton assembly and cell polarization; present in the actin cortical patch of the emerging bud tip; dimer in vivo [Source:SGD;Acc:S000005187]) HSP 1 Score: 52.373 bits (124), Expect = 1.277e-6 Identity = 41/124 (33.06%), Postives = 63/124 (50.81%), Query Frame = 3
Query: 7671 IVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGK----CGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEAL 8030
I+ A LVK A Q E+ + + P +N ++W+ GLISAA+ VA AT L +A ++ + ++ I ASK+VAA T L+ A +VK+ SK +L+ V A +L
Sbjct: 779 IIDAVVALVKAAIQCQNEIATTTSI-PLNQFYLKN-SRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSL 900
BLAST of Talin vs. Ensembl Nematostella
Match: EDO47777 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL15]) HSP 1 Score: 931.784 bits (2407), Expect = 0.000e+0 Identity = 809/2711 (29.84%), Postives = 1364/2711 (50.31%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERM---KTMTLKR--------GKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQ-PIAIRNDSKIG--QGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQ----PLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIV--LPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMD--TAAESVA-RGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPIL---DSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG----VLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTN----NQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHT-------LIFQS--IKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIG---QVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATE 8024
+L+I +V N +L+ + + V + R + +++P V ++GLF + D + WL+ ++ +++YPL D ++ L +KS++R + I+ MD KTL++DDS ++ +++ +C KMGISN EE+SL+ E ++E+ KT TLKR + + RD K++++K+KL T+D++ WL H KTLR+ G D+ +++RRKYF+SDQNVD +DP+QLNLLYVQ ++ I+DGTHP EEA QL IQ Q + G+ K K I +LKE LPKEYVK+K IDKKI ++ K +G + + Y QLCR LKTYG+TFFLVKEK++ KNKLVPRL+GI+KE ++RVDEKTKE+++ WPLTTVRR+AA+ + F+LDFGDY++ Y +QT EGEKI+QLI GYIDII+KK+K + D +E +AM E+ VAPSK ++D+ T S+ ++ LP VV G GS++ + ++ G G+ + + + +L+ ++A M + + + A E+L + + + LG+D +S +++ TLD+++ V L +++ + +++ + E D N Y AA+ I N L + I+ + + D +D + L++AA+ L AF LL A++ E G+K S L+ A VG + LL + + ++ +T++TLL A+ +AN + +V +K +VA + T Q +I AAK++ TS L++ K+V SI + Q+Q+ SA+QV +V++ + P E +V+ + + K+++ + L A++RL ++GN+ EMV QA+ILA+A + L + + A VQ D D Q+RL+ AA+ L DA KLV A K + E Q+ L +AA + S + A + ++++L K LE A ++ QLV ++Q AA R AS Q+ + + + + + L E + C+ NP D N+Q NL+N + I + +L+ S+A P + +P S L +++ SL +L+ ++A V D L+ L + D A E A G+L PLPGE ES + +G++SK +L N + G+ +A++ +++ L + RG+AA S D+ +N+ + VI ++I + + + + L + + + ++ V +P +E++ + + ++ + K E T+ + + Q + + + A N D+++ S + + L K + S+ ++ +GL L + P+ + + ++++ N ST L + + K +L AA V+DSIN LL+AC S P Q+ C+S+ R ++A+ T L + P P+N+ +Y C+++V S+ L M I + K D N F +I+ S + + ++ QA Y + + SS P L + I ++ C S+ + ++S+ AT + S++C K + +P + + + A K VA T NL+K I + + + ND+ K+C + N+VE LT A +P P I+++ R AQ + A + + AA V + + A Q K + RL +K +APGQRE E++ V+ NLD+A++ N S + ++ + +RM +L ++ + P+ ++ +S+ E +G V + +L P+ +++ A L+ +S+ +G++++ TKTV E+ M+ +T + + E S+ DL I+ AS G + ++ SI K+ L+E+ P D+ A+ +++Q K + D V + K ST K L++ D++ + + H+ V V +G +++ V +G+SC+ L++ Y +K+ QV +++ L+ L + SRGTQ CI AA++V +V+DLDT ++FA + + N + + A +EDI + K LV D +++V S Q+ LA A +++V ++L VK A A+GS+ S AQ +LLNA RDVA AL N TK N + + + LKSS +TMV +V L+ +VK++ED RGTRA+E+S EA+++ L + D S E+L+ TK + LA+ KA+AA + Q+D++ AAN+GRKA+T+++ + A + +D D ++ +G+ + +I++ + K K ++ S+++A + ++ +A LK + + EDPN IAENELL AA+ IE AA+K+A L+P K K+ + F+ QI+ A +I +AT LVK AS +Q+EL++ G++ S + + QWS GL+SAAR VAAAT+ L ++A A VQG +RL++ + QVA+ TA LLLAC+VK+DA S T +RLQ AG+AVKRA E
Sbjct: 4 SLKINVVKNNSIKTLQFNPEATVAEALRIIREKVPDASPGKVADYGLFKQEDDPAKGKWLEPARSINFYPLKDGDM-LEYKSKIRLIKIKFMDGNVKTLQIDDSHTVGQILETVCVKMGISNPEEFSLLVEGKDDEKEEAEKTSTLKRVMMKDVPIKRLEERDRKKMDQLKKKLHTEDDVQWLDHDKTLREQGTDDSHTVVMRRKYFYSDQNVDIKDPVQLNLLYVQCRDGILDGTHPCTQEEASQLGAIQIQVQFGDYEESKYKLI--DLKEVLPKEYVKSKNIDKKIKEEHRKFNGLDELQGRYKYVQLCRGLKTYGVTFFLVKEKMKGKNKLVPRLLGITKESILRVDEKTKEVMKTWPLTTVRRWAASPNSFTLDFGDYTESYYSVQTNEGEKISQLIAGYIDIILKKRKGMEGYDPDFDEVSAMEEDQVAPSKGT-----YLDRQTNKVGHASVGSVA-LP-----AVVRAGGQGSSRYSMGKMEPAQYGTVSGSAHSAHRPPMLHNLTPAQQAYMSSLSQGIDSVDTADEELKRPVNIVALGSDPASLKWKQNTLDVSRQNVASRLAALSASCASIVNVTSG-EPGDTN--YTAAGAAVHVISANLQDLSKGIKLIAGLL---DNQD-DSSKLLDAARGLAGAFSLLLKAAQ------------EGAGGDKEKRSQ--LLNAAGNVGSSGAQLLEYMGEPE-----VDQETQETLLKLAQAVANATATLV--LKAKNVA-SQCPDTAQQNKVIGAAKDTAMTTSQLVACVKLVVPSITSQMCQEQVVESAKQVAKAVEDTEGACKGACDPDSENMNVLIDAAQGVRDALNALLKKVREGGERPTEGEKYGETCDDILGATDRLFNSMGNAGEMVKQAKILAQATSSLVSGIKSEAEVQD------------DDDNQKRLLAAAKLLADATAKLVEAAKGAARNPNDADE-QEKLKRAAEDLRSATNTAASDALKKKLVKRLENAAKEATGQTTQLVAAAQAAAPVNRNQASQQQLMDQLKPVEDQIARLLESLRDCSN---NPDDANSQLNLINVSKMFIPPVAKLVAFSKAALPTIDEPMYASQLGNFSKSTAASLNELRNAAEKAAEACGTLEV-------DSALKRLKALDDDLKAVERAAEEGKLVPLPGENPESSALELGATSKTVGSSMAQLLTAAAQGNESYT-------GI------AARDTANALKNLTQAVRGVAAGTSDKDAQKNIVQAARGVIQESAKLINEAKKALNNPGDPNNQ----QRLAQVAKGVSQALNNCVNCLPGQREVEDSIKAVSAASQALSKE--------EFPPTTEPYQRNQEKLSQSGAALNAAASDVVSASRGSPNQLATSTKNFSLSYQGLVNSGLMLAGQAPDEAAK-EALVRNLRNTSTASSKLLLAARSLVSDPNAPNAKNALANAARAVTDSINTLLNACMSAAP-GQKECDSALRNIQAVNTIL--DNPVEPVNDSTYFDCLETVAGKSKDLTEAMPVIADSIKQADYNKFDRSIKRASNAVCALTETAAQAAYLVAVADP------SSVAGKPGLIDQEQFINAKQEINDACQSLLNPDSSQQRVLAAATAVAKHTSALCNACKVASAKTHEPAAKRQFVQAAKDVANNTANLVKQIKTFAGN---MNDDNRKSCASATRPLRNSVESLTAYA-LSPDFAPVPAKISDEARSAQVPVIMAGKSIANSGANYFNAAKLSVVNPQDTNAWQNLQQTAKQVADAMRRLITAIKDNAPGQRECDLAIEDINTVINNLDQASL----ANISDGLEPRTEQPLQVYQERMMQNLGEMNPVVEPLG--VAAKSQPENIGHLVAKMTDFLVPLCDAAIGAASLMKNSKRKGDLLDQTKTVAESAAQMMYATKTAGGNPQVHHAHPAVDEAAQSMHDAIYDLKNTIEQDASESGIVSGLVDSISKT---LSES----PYDSVDAYRRGAYEPFVVYQERMTKAMKDLVR--------KAQDMVGKSSTDPTKLGP----LAK----DISNLYDDIAHNARGAVATVGNADVAG---------RIRNGVQGLGESCIGLVQSAGAVQATPTDPYSKKDLADRSRQVAEKVSHLLAALITGSRGTQACINAASTVQGIVSDLDTTVMFATA--------GTLNPETPGETFADHREDILRTAKVLVEDTKRLVASAQASQDVLATAAESSVGSVSKLTDHVKLGAAAMGSDDS------------DAQQMLLNAARDVASALGSLINSTK-NASGKSPNDPAMEPLKSSAKTMVSNVSSLLMTVKTVEDKTMRGTRAMESSNEAIKQAIMVLNSPTLPARDA----------------------------SPEDLIRSTKGVTLATAKAVAAGNSCNQDDVIAAANMGRKAVTEMLS--------------------ICKAAAVKADTDEVKYATIVAGRDTAAAYGE-VSELVINILQ---------KPTPEKKARLMPLSKKVAEGVGKLVRTAETLKGSEWVNPEDPN---IIAENELLGAAASIEAAARKLAELRP-KPRPKEADDSLNFEEQILEAAKAITAATVALVKSASAAQRELIATGKIF-SAGTDAREDNQWSQGLVSAARTVAAATQTLCEAANAAVQGNASEERLVAGANQVASSTAQLLLACRVKADAHSATQRRLQVAGNAVKRAGE 2487
BLAST of Talin vs. Ensembl Nematostella
Match: EDO49269 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH05]) HSP 1 Score: 80.1073 bits (196), Expect = 1.457e-14 Identity = 52/174 (29.89%), Postives = 87/174 (50.00%), Query Frame = 3
Query: 705 NLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKS-----------------IHSNLKEFLPKEYVKTKGIDKKIIAQYEKLS--GKSDKDVKVIYAQLCRSLKTYGITFFLVKE---KVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATA 1160
++LY Q + A++ G P ++E+AI L+ +Q E +M+P A++ S LK+ + + K K I K+I Q E G S+++ K Y C+++ YG FF +KE + + V RL GIS + V+ +DE+TK ++ NW V+R+ A
Sbjct: 1485 SILYEQCQKAVVGGGLPCHVEDAIYLSALQLYIE--DMSPPSAETRGRLEGWFLQGTGSEKLSASRLKQAVHPSFYKVKNIAKRIRGQREHFQNEGLSERNAKHNYIDCCQAMPGYGCRFFQLKECLGTISRNSGHVDRLFGISPKKVVLLDERTKGVVGNWQFNDVKRWKLVA 1656
BLAST of Talin vs. Ensembl Nematostella
Match: EDO35194 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM91]) HSP 1 Score: 73.1738 bits (178), Expect = 1.192e-13 Identity = 65/229 (28.38%), Postives = 112/229 (48.91%), Query Frame = 3
Query: 7530 ENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEA-TEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGH 8213
+NE+ A + AA +I + K+ +K TG + +G+I+ +C S++ A L+ + Q+E+V G+ + + +W+ GLISAA+ V + L DSA VV GK + L+ AS ++ A TA L+ A +VK+ S Q L A V + +V A T ++D ++P D ++ + R + +Q ++ E L R K +R+ H
Sbjct: 21 DNEINATAELVADAAARIEEM-LNKTREKYTGVQLEVNGRILDSCTSLMQAIKVLILKSKDLQEEIVGVGKGTATAKEFYKRHHRWTEGLISAAKAVGWGAKVLVDSADKVVLGKGKFEELVVASNEITASTAQLVAASRVKAHRGSNKLQALHGASKDVVESAAGVVASAKTGAEMIEDKTVP---DYSKLTLTQAKRLEMDSQVRLLELESNLTKEREKLGQLRRIH 245
BLAST of Talin vs. Ensembl Nematostella
Match: EDO35658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKY6]) HSP 1 Score: 68.9366 bits (167), Expect = 3.551e-11 Identity = 72/309 (23.30%), Postives = 136/309 (44.01%), Query Frame = 3
Query: 351 DDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLL-YVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAK--SIHSNLKEFLPKEYVKTKGID---KKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGD-YSDENYVIQTTEGEKIAQLIGGY 1256
DD+ + EVD E I ++G+ + E +SL ++ + K +++ G FD + + + LK G T + ++ +K + V +DP + Y Q + G H EEA QLA + + + G DK++ +I +KE +P + VK D + I+AQ+ K G++ + K+ + ++ T+G FF VK+ N L+ I+K V ++ +TKE++ +P T + +++ + F + G + +T+ G K+ L+ Y
Sbjct: 1612 DDSDQAFEVDSGTKAKEFCNIIAQRLGLKSAEGFSLFVKITD----KVISVPEGDF---FFDFVRHLTEWLKKA--------GPTKDGRTPNLTYQVFFMKKLW--TNTVVGKDPAADCIFHYHQELPKYLRGYHKCIKEEAAQLAALIYRVKFGE---DKSQFQNIPRMVKELIPHDLVKQMSPDEWKRAIVAQFNKHPGRTKSEAKISFLKIIYRWPTFGSAFFEVKQGTEP-NFPDNLLIAINKSGVNLINPQTKEILATYPFTKISNWSSGNTYFHMTIGSLVKGSKLLCETSLGYKMDDLLTSY 1899
BLAST of Talin vs. Ensembl Nematostella
Match: EDO38965 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBA4]) HSP 1 Score: 52.7582 bits (125), Expect = 1.849e-6 Identity = 37/148 (25.00%), Postives = 70/148 (47.30%), Query Frame = 3
Query: 639 LLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLP----KEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGIS 1070
+LL FF + ++P+ + L ++Q + I G+ + E +LAG QA G+ +A LP KE+ ++K++ +Y+ G++ + V Y + +SL TYG+ ++ VK+K +P +G+S
Sbjct: 74 ILLFAVRFFVPNILILKEPVTVELFFLQARALIFKGSIQCDTETVFELAGYVLQAVYGDFTSVEATKQDLKKIAVLPTRTLKEHPSISYCEEKVLTRYKLCVGQTKGEAIVRYLCIFQSLPTYGVHYYEVKDK-----GSIPWWLGLS 216
BLAST of Talin vs. Ensembl Medaka
Match: tln2a (talin-2 [Source:NCBI gene;Acc:101173776]) HSP 1 Score: 982.63 bits (2539), Expect = 0.000e+0 Identity = 845/2767 (30.54%), Postives = 1435/2767 (51.86%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGN-LIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNL-THSALTLLAKQLNESHDCMLMTGLQLIAEV--PNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSD--VNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQL--SLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKI-VEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T +YD CR + R+P+ + ++GLF+SD D + WL++ + + YY L GD +L +K + R I+ +D KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+D+ + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AGIQ Q + G+ K K +LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+GI+KE VMRVDEKTK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F E S+A LP GV+ G +G+ + + + Q Q + + LS ++ALM I +++ ++ A DL + + LG D +S+ + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + E+D+ GGN L++AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV++ IQ E ++ +Q+ +++ +++ L QH + T+ +P+ ++ +E + ++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + ++Q AA + + A++ Q+ + + + + P+++ + P D +AQ L+ A Q +Q +++ S+++ P V D + L +N T LA+L+ Q+A P + + +QTL S + A + +L PLPGE++E + +GS+SK+ +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I + + ++ A + L + + ++ V +P +++D LKS E K +++ P AN KS + Q+E A NQ+ G+++ + + S L + + + + D L G+++ ++Q Q+ S LK++S S+ LL A S S D K L AA V+DSIN L++ C P Q+ C+++ R+LEA++ L + PS P+N+ SY C++SV E S+ L M I CK D F ++ S + + ++ QA+Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S EN + A ++ VE LT A +NP ++ Q G AQ I Q++ M++ S LL+ A +L + K P + +T + L ++ APGQRE + + + +R++++A++ S N S D I+ + + QL +++++ + I P+ + + + LG V + Y P+ ++S +A L + + ++ TKT+ E+ L M+ +E ++ D + + L K DD+M ++ AS G + M+ SI ++ A+L E P D S +K +K I+VT ++ TK + + ++ L+ ++ DY L V ++S ++ ++K V +G C+ L++ + ++E I R+ +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+F + +N+END+ S A +E+I K K+LV D + +V QE LA A ++ + QL VK A +IGS+ Q +L+NAV+DVA AL + + TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ ++ Y K + E + MTK + +A+ KA+AA + +QEDI+ AN+ RKAI+D++ + F P VS E V+ +++ VE G ++ L + L + E K Q+ +S+R+A ++ E+ +A +K + D EDP IAE ELL AA+ IE AAKK+ LKPR K D E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQ AG+AVK+A++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ P
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAIYDACRIIRDRVPEAQTGQASDYGLFLSDEDPRKGIWLESGRTLDYYMLRNGD---ILEYKKKQRPQKIKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKEDGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGSHIEHKHKPGFLDLKEFLPKEYIKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF--NRVGRVEHGSVA----LP-----GVIRSGSIGT-ESLTLGTMPSPQQQITMGQMHRGHMPPLSSAQQALMGTINTSMQAVQKAQIDLGEVDNLPPLGQDMASKVWIQNKMDESKHEIHSQVDAITAGTASVVNLTAGDP---TDTDYTAVGCAITTISSNLTEMSKGVKLLAALM----EDDVGGGNDLMKAARTLAGAVSDLLKAVEPASGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVESCIQACLSATEDGELL-KQVSAAASVVSQALADLLQH--VRQYTSRGEPIGRYDQATDTIMTVTESIFISMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKLINRLENAAKQAAAAATQTIAAAQNAAASNKNTAAHQQLVQSCKAVADHI-PQLVQGVRSSQAKPEDLSAQLALIIASQNFLQPGSKMVTSAKSSVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPMEIDSALTA----IQTLRSELQDAKLAATTTQLKPLPGESLEKCAQDLGSTSKSVGSSMAQLLTCAAQGNEHFT-------GI------AARETAQALKTLAQAARGVAASITDPKASAAMLDSARDVMEGSALLIHEAKQAL----ISPADAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGEASKKLLMDAIP---PAN--KSFQEAQNELNQTAADLNQSAGEVVTATRGSSSQLAVASGKFSHDFDEFLDAGIEMAGHTQKKDDQVQVISNLKNISMASS-----KLLLAAKSLSVDPAAANAKNLLAAAARAVTDSINQLITLCTQQAP-GQKECDNALRELEAVRGML--DNPSEPVNDLSYFDCIESVMENSKVLGESMAGISQNCKISDVTAFGDSVGSASKALCGLTEAAGQASYLVGVSDPNSQAGHQGLV-DPIQFAKANQAIQMA--CQNLVDPESSPSQVLSAATIVAKHTSALCNACRLASSKTTNPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENRSRCQVATTPLIEAVENLTTFA-----SNPEFASVPAQISNEGSAAQEPIIQSARSMLDSSTLLLKTARSLALNPKDPPTWSVLAGHSRTVSDSIKSLITAIRDKAPGQRECDSSIDNINKCIRDIEQASLAVVS------QNLPSRDDISLEALQEQLTSTVQEIGHLIDPVST--AARGEASQLGHKVTQLAGYFEPLIKASVGVASKLNDHQQQMTFLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEVGMVGGMVESIAEAMAKLDE--GTPPEDEGSFVDYQTSMVKH----------SKAIAVT--AQEMMTKSVTSPDELGALA-----------SQVTVDYSQL--AVQGRLASHTAEPEEIGFQIKTRVQELGHGCIYLVQKAGALQISPTDSFTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMF-----ASAGTLNAENDE----SFADHRENILKTAKALVEDTKMLVSGAASGQERLAQAAQSSAKTITQLTDVVKLGAASIGSDDP------------ETQVVLINAVKDVAKALAELISATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQEMALFQS-------------KDSPY---------------KTTTPEEFIRMTKGITMATAKAVAAGNSARQEDIIHTANLSRKAISDMLTTCK--------------QAAFH---PEVS-------EDVRTRALRFGVECTTGYIELLEQVLLVLLRPSPE------QKQQLAASSKRVACAVTELIHTAEAMKGSEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKAD--ETLNFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQVAGNAVKKASDNLVRAAQKAAFDKADEDNVVVKT------KFVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQQYKFLP 2533
BLAST of Talin vs. Ensembl Medaka
Match: tln1 (talin 1 [Source:NCBI gene;Acc:101157630]) HSP 1 Score: 981.474 bits (2536), Expect = 0.000e+0 Identity = 855/2775 (30.81%), Postives = 1423/2775 (51.28%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDS--KIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEAS-RLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAH----QDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLN-NYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIR---AVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLIN-SNLTHSALTLLAKQLNESHDCMLMTGLQL--IAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRE-----LATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQIAKYTPITNPAVKT----ITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLM-ENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGE--DKLKKCVVAVGQSCMDLI------------RYDQKEFIGQVR---SRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSN---LKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSD---KIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKE---NSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHR-DVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
M L + I N +++ + T+VYD CR + +R+P+ + ++GLF+SD D + WL+ K + YY L GD L +K + R L IR +D T KT+ VDDSK ++++++ IC ++GI+N++EYSL++++ E ++ +T TLK+ KT +RD K+EK+KQKL TDDELNWL HG+TLR+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AG QCQ + G+ K KS +LKEFLPKEY+K KG +KKI ++ ++ + KV Y +L RSLKTYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTKE+IQ W LT ++R+AA+ F+LDFGDY D Y +QTTEGE+IAQLI GYIDII+KK+K+KD+ + +EE+ M+E++V+P K+ V+ F N + + G + + + R G+ P + + S + Q + Q + + L+ ++AL I +++ ++AA L+ + LG D +S+ +RK +D +K + + ++T T +++ + D DY + A+ TI N ++ + ++ + + ++E NG L+ AAK L A D+L ++P N E + L++A VG+ S LL HI +D + Q ++ L+ AK +AN + ++K +VA K T+ + Q +I AA +TS L++ +VVA +I P+ Q+QL +++ V SV+ + Q ++ +Q+ + +++++L QH+ + H + L+ +E + +++G++ EMV QA+ILA+A ++L + + A +S D + R+L+ AA+ L DA K+V A K + + E QQ L +AA + + A I++RL LE A +Q A A Q + ++Q AA T + + Q+ + + E + P+++ + P P+AQ L+NA Q +Q +++ +++A P + D + L+ +N ++LA+L+ Q+A + N + ++ L + A S G+L PLPGET+ S + +++KA + +L + + NY G+ SA+++ ++++ L+ ARG+AA TD + V+DC ++ ++I+ K A + A + L + M + ++ V +P +++D + +++ E + ++ P + KS ++Q++ A NQ+ +++ S T L + + L G+ + ++ +Q Q+ S LK++S +S+ LL K L S S ++ L AA V+DSIN L++ C P Q+ C+++ R+LE++K L E P+ +N+ S+ +C+ SV E S+ L M I K + +F ++ S + + + QA Y +G+ N ST L Q A + I MA N + C + AT + S++C + + +S+ + + + + K VA T NL+K+I + + S EN E KA G ++ V+ LT A +NP + I+ +G A I A+ M+E S L++ A +L + K P + +T + +L ++ APGQRE + E L +R +D+A++ S + + + S+ + ++M S+ ++ N I P+ ++ +S+ LG V + SY P+ ++ A + S+ + V++ TKT+ E+ L M+ +E + Q+ + E+V +K DDL + AS G + M+ +I + ++ +++ LD H F + T K I+VT +E + N D D+ +L +++ +L A ++ E +KK V +G +C L+ + +KE I R +++ ++ LQ+ +RGTQ CI AA++V+ ++ADLDT I+F ++ EN + + A +E I K K+LV D + +V QE LA A ++V +L VK A ++GS E Q +L+NAV+DVA AL + + TK A K D + LK+S + MV +V L+K+VK++ED +GTRALE ++E +++E V SSD K S E+ + MTK + +A+ KA+AA + +QEDI+ AN+ R+AI D++ KE P + +D RR + E + ++EH V +I K + K Q+ S+R+A S+ E+ ++A +K T D EDP IAENELL AA+ IE AAKK+ L+PR + K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT NL ++A + VQG ++LIS++KQVAA TA LL+AC+VK+D DS+T +RLQAAG+AVKRA++ LVK A + D +D MV + +I AQ +++ KE+ELE R + IRQ
Sbjct: 1 MVALSLKIGVGNVVKTMQFEPSTMVYDACRIIRERVPEAQLGQPNDYGLFLSDEDPKKGIWLEAGKALDYYMLRNGD---TLDYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIGITNYDEYSLVHDIGEEKKEETTGTLKKDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTLREQGVEETEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGDHNESKHKSGFLDLKEFLPKEYIKNKG-EKKIFQAHKNCQNMTEIEAKVSYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGMEGDEESTMLEDSVSPKKSTVLQQQF----------NKMGKV----ETGSVALPAIMRSGAGGPESFQMGSMPQAKQHITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQASLEDFDTLPPLGTDAASQAWRKNKMDESKHEIHSQVDAITAGTASMVNLTAGDP---AETDYTAVGCAVTTISSNLTEMSKGVKLLAAL---MEDEGGNGQLLLGAAKNLACAVSDMLKTAQPANTE-----------------PRQNLLQAAGNVGQTSGELLSHI------GETDTDPQFQEMLMQLAKAVANAAA--ALVLKAKNVAQK-TEDSAQQNRVIAAATQCALSTSQLVACTRVVAPTISSPVCQEQLIEASKLVAKSVEGCVGASQSATNDEGLL-KQVGVAATGVTQTLNELLQHIKQYASGGHPIGRHGEATDRILNVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKMDAEGES------------DLENSRKLLSAAKLLADATAKMVEAAKGAAANPD-SEEQQQKLREAAEGLRMATNAAAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASTNKNQGAQQQLVQSCKVVAEQI-PQLVQGVRGSQSQPDSPSAQLALINASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCAKNLASALAELRTASQKAQDACGQLEIDNALVM----VRDLEKDIQEAKASAREGKLKPLPGETLGKCSQDLSTNTKAVTSAIAQLLSEATQGDENYA--------GI------SARDMAQTLKSLVSAARGVAA---STDDP----AARGAVLDCAGDVLDKSANLIEEAKRAIAKPGDAESQQRLAQVAKAMSQALNRCVNCLPGQRDVD---NAIRTVGEASKTLLADSFP-----SSGKSFQELQAQLNEVAAGLNQSANEVVQASRGTTQDLAKATSKFGQDFSNFLDAGVDMAGTSQSKEDQTQVVSNLKTISMSSSKLLLAAKALSTDSSSPNLK---NQLAAAARAVTDSINQLITMCTQQAP-GQKECDNALRELESVKGML--ENPTEAVNDLSFFECIDSVMENSKVLGESMAGISHNAKNSNLPEFGDSVSAASKALCGLTEGAAQAAYLVGVSDPN------STAGQKGLVDPTQFAR--ANQSIQMACQNLVDPACTQSQVLSAATIVAKHTSALCNACRLASSQTSNAVAKRQFVQSAKEVANTTANLVKSIKALDGAFSQENREKCKAATGPLIEAVDNLTAFA-----SNPEFASIPAHISPEGHAAMEPIVAAAQTMLESSTGLIQTARSLAVNPKDPPTWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLNGCIREVDQASLAAI----SQHLTPREDISMETLHEQMAASVHEISNLIDPV--AVAARSEASQLGHKVSQMASYFEPLIMAAIGTASKILSSQQQMAVLDQTKTLAESALQMLYTAKEAGGNPKAAHMQEAVEESVQMMKEAVDDLGATLADAASAAGAVGGMVDTINDAINKMEDSHT---LD----HDGTF-----VDYQTTMVKTAKAIAVTV---QEMVTKSNTNPD----------DLGGLANQLTNNFGNLANEA----KYAALTAENDEIGSHIKKQVGELGFTCTGLVTKAGALQCSPNDTFTKKELIESARKVSEKVSHVLASLQAGNRGTQACITAASAVSGIIADLDTTIMF-----ATAGTLHRENAE----TFADHRECILKTAKALVEDTKLLVSGAGASQEKLAQAAQSSVSTITKLAEVVKLGAASLGS------------EDPETQVVLINAVKDVAKALSNLISATK----AAAGKPHDDPSMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIKQEL-------------------------------TVFCSSDPPAKTTSPEDFIRMTKGITMATAKAVAAGNSCRQEDIIATANLSRRAIADMLR--------SCKEAAYHPE--------VNADVRRRALRFGNECATGYLGLLEH----VLVIIQ------------KPSHDLKQQLATYSKRVAGSVTELIQAAEAMKGTEWVDPEDPT---VIAENELLGAAAAIEAAAKKLEQLRPR-TKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATNNLCEAANSAVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSQTMKRLQAAGNAVKRASDNLVKAAQKAAFDAEDDQAVVV----KSKMVGGIAQIIAAQEEMLRKEKELEEARKRLAMIRQ 2524
BLAST of Talin vs. Ensembl Medaka
Match: tln2a (talin-2 [Source:NCBI gene;Acc:101173776]) HSP 1 Score: 980.319 bits (2533), Expect = 0.000e+0 Identity = 844/2767 (30.50%), Postives = 1435/2767 (51.86%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGN-LIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNL-THSALTLLAKQLNESHDCMLMTGLQLIAEV--PNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSD--VNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQL--SLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKI-VEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHP 8228
+L+I + N +++ + T +YD CR + R+P+ + ++GLF+SD D + WL++ + + YY L GD +L +K + R I+ +D KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+D+ + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AGIQ Q + G+ K K +LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+GI+KE VMRVDEKTK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F E S+A LP GV+ G +G+ + + + Q Q + + LS ++ALM I +++ ++ A DL + + LG D +S+ + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + E+D+ GGN L++AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV++ IQ E ++ +Q+ +++ +++ L QH + T+ +P+ ++ +E + ++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + ++Q AA + + A++ Q+ + + + + P+++ + P D +AQ L+ A Q +Q +++ S+++ P V D + L +N T LA+L+ Q+A P + + +QTL S + A + +L PLPGE++E + +GS+SK+ +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I + + ++ A + L + + ++ V +P +++D LKS E K +++ P AN KS + Q+E A NQ+ G+++ + + S L + + + + D L G+++ ++Q Q+ S LK++S S+ LL A S S D K L AA V+DSIN L++ C P Q+ C+++ R+LEA++ L + PS P+N+ SY C++SV E S+ L M I CK D F ++ S + + ++ QA+Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S EN + A ++ VE LT A +NP ++ Q G AQ I Q++ M++ S LL+ A +L + K P + +T + L ++ APGQRE + + + +R++++A++ S N S D I+ + + QL +++++ + I P+ + + + LG V + Y P+ ++S +A L + + ++ TKT+ E+ L M+ +E ++ D + + L K DD+M ++ AS G + M+ SI ++ A+L E P D S +K +K I+VT ++ TK + + ++ L+ ++ DY L V ++S ++ ++K V +G C+ L++ + ++E I R+ +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+F + +N+END+ S A +E+I K K+LV D + +V QE LA A ++ + QL VK A +IGS+ Q +L+NAV+DVA AL + + TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ ++ Y K + E + MTK + +A+ KA+AA + +QEDI+ AN+ RKAI+D++ + F P VS E V+ +++ VE G ++ L + L + E K Q+ +S+R+A ++ E+ +A +K + D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQ AG+AVK+A++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ P
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTAIYDACRIIRDRVPEAQTGQASDYGLFLSDEDPRKGIWLESGRTLDYYMLRNGD---ILEYKKKQRPQKIKMLDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKEDGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGSHIEHKHKPGFLDLKEFLPKEYIKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF--NRVGRVEHGSVA----LP-----GVIRSGSIGT-ESLTLGTMPSPQQQITMGQMHRGHMPPLSSAQQALMGTINTSMQAVQKAQIDLGEVDNLPPLGQDMASKVWIQNKMDESKHEIHSQVDAITAGTASVVNLTAGDP---TDTDYTAVGCAITTISSNLTEMSKGVKLLAALM----EDDVGGGNDLMKAARTLAGAVSDLLKAVEPASGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVESCIQACLSATEDGELL-KQVSAAASVVSQALADLLQH--VRQYTSRGEPIGRYDQATDTIMTVTESIFISMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKLINRLENAAKQAAAAATQTIAAAQNAAASNKNTAAHQQLVQSCKAVADHI-PQLVQGVRSSQAKPEDLSAQLALIIASQNFLQPGSKMVTSAKSSVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPMEIDSALTA----IQTLRSELQDAKLAATTTQLKPLPGESLEKCAQDLGSTSKSVGSSMAQLLTCAAQGNEHFT-------GI------AARETAQALKTLAQAARGVAASITDPKASAAMLDSARDVMEGSALLIHEAKQAL----ISPADAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGEASKKLLMDAIP---PAN--KSFQEAQNELNQTAADLNQSAGEVVTATRGSSSQLAVASGKFSHDFDEFLDAGIEMAGHTQKKDDQVQVISNLKNISMASS-----KLLLAAKSLSVDPAAANAKNLLAAAARAVTDSINQLITLCTQQAP-GQKECDNALRELEAVRGML--DNPSEPVNDLSYFDCIESVMENSKVLGESMAGISQNCKISDVTAFGDSVGSASKALCGLTEAAGQASYLVGVSDPNSQAGHQGLV-DPIQFAKANQAIQMA--CQNLVDPESSPSQVLSAATIVAKHTSALCNACRLASSKTTNPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENRSRCQVATTPLIEAVENLTTFA-----SNPEFASVPAQISNEGSAAQEPIIQSARSMLDSSTLLLKTARSLALNPKDPPTWSVLAGHSRTVSDSIKSLITAIRDKAPGQRECDSSIDNINKCIRDIEQASLAVVS------QNLPSRDDISLEALQEQLTSTVQEIGHLIDPVST--AARGEASQLGHKVTQLAGYFEPLIKASVGVASKLNDHQQQMTFLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEVGMVGGMVESIAEAMAKLDE--GTPPEDEGSFVDYQTSMVKH----------SKAIAVT--AQEMMTKSVTSPDELGALA-----------SQVTVDYSQL--AVQGRLASHTAEPEEIGFQIKTRVQELGHGCIYLVQKAGALQISPTDSFTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMF-----ASAGTLNAENDE----SFADHRENILKTAKALVEDTKMLVSGAASGQERLAQAAQSSAKTITQLTDVVKLGAASIGSDDP------------ETQVVLINAVKDVAKALAELISATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQEMALFQS-------------KDSPY---------------KTTTPEEFIRMTKGITMATAKAVAAGNSARQEDIIHTANLSRKAISDMLTTCK--------------QAAFH---PEVS-------EDVRTRALRFGVECTTGYIELLEQVLLVLLRPSPE------QKQQLAASSKRVACAVTELIHTAEAMKGSEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLNFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQVAGNAVKKASDNLVRAAQKAAFDKADEDNVVVKT------KFVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQQYKFLP 2534
BLAST of Talin vs. Ensembl Medaka
Match: tln2a (talin-2 [Source:NCBI gene;Acc:101173776]) HSP 1 Score: 923.309 bits (2385), Expect = 0.000e+0 Identity = 816/2667 (30.60%), Postives = 1383/2667 (51.86%), Query Frame = 3
Query: 348 MDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGN-LIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPL------VTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNL-THSALTLLAKQLNESHDCMLMTGLQLIAEV--PNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSD--VNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQ----GRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQL--SLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV---QECETLSTTTNNQDLMENVSSL-KIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKI-VEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLK--PSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATE---HRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQ 8207
+D KT+ VDDSK++ EL++ IC+++GI+N+EEYSLI E ++E + T TLK+ +T +RD K+EK+K KL TDD+LNWL H +T R+ G+D+ + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ I++G+HPV+ ++A + AGIQ Q + G+ K K +LKEFLPKEY+K +G +KKI +++ ++ + KV Y +L RSL+TYG++FFLVKEK+++KNKLVPRL+GI+KE VMRVDEKTK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD + +EE+ M+EE+V+P K+ ++ F E S+A LP GV+ G +G+ + + + Q Q + + LS ++ALM I +++ ++ A DL + + LG D +S+ + + +D +K + + ++T T +++ + D + DY + AI TI N ++ + ++ + + E+D+ GGN L++AA+TL A DLL A +P + E + ++ A +G+AS LL I + +D +Q D L+ AK +AN + +V +K +VA + + T Q +I AA +TS L++ AKVV+ +I P+ Q+QL + + V SV++ IQ E ++ +Q+ +++ +++ L QH + T+ +P+ ++ +E + ++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + ++Q AA + + A++ Q+ + + + + P+++ + P D +AQ L+ A Q +Q +++ S+++ P V D + L +N T LA+L+ Q+A P + + +QTL S + A + +L PLPGE++E + +GS+SK+ +L N + + G+ +A+E ++++ L + ARG+AA + ++ + + DV++ +I + + ++ A + L + + ++ V +P +++D LKS E K +++ P AN KS + Q+E A NQ+ G+++ + + S L + + + + D L G+++ ++Q Q+ S LK++S S+ LL A S S D K L AA V+DSIN L++ C P Q+ C+++ R+LEA++ L + PS P+N+ SY C++SV E S+ L M I CK D F ++ S + + ++ QA+Y +G+ N+ V +PI + A M+ C ++ +S AT + S++C + + +++P + + + K VA +T NL+KTI + S EN + A ++ VE LT A +NP ++ Q G AQ I Q++ M++ S LL+ A +L + K P + +T + L ++ APGQRE + + + +R++++A++ S N S D I+ + + QL +++++ + I P+ + + + LG V + Y P+ ++S +A L + + ++ TKT+ E+ L M+ +E ++ D + + L K DD+M ++ AS G + M+ SI ++ A+L E P D S +K +K I+VT ++ TK + + ++ L+ ++ DY L V ++S ++ ++K V +G C+ L++ + ++E I R+ +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+F + +N+END+ S A +E+I K K+LV D + +V QE LA A ++ + QL VK A +IGS+ Q +L+NAV+DVA AL + + TK D + LKS+ + MV +V L+K+VK++ED RGTRALE ++E +++E ++ ++ Y K + E + MTK + +A+ KA+AA + +QEDI+ AN+ RKAI+D++ + F P VS E V+ +++ VE G ++ L + L + E K Q+ +S+R+A ++ E+ +A +K + D EDP IAE ELL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ P+ + ++ QWS GLISAAR+VAAAT +L ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQ AG+AVK+A++ LV+ A + + +D + T V + +I AQ +++ KERELE R K IRQ
Sbjct: 2 LDGAVKTIMVDDSKTVGELLVTICSRIGITNYEEYSLIQETVEEKKEDGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDDNETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGIQAQIQFGSHIEHKHKPGFLDLKEFLPKEYIKQRGAEKKIFQEHKNCGEMTEIEAKVKYVKLARSLRTYGVSFFLVKEKMKSKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQF--NRVGRVEHGSVA----LP-----GVIRSGSIGT-ESLTLGTMPSPQQQITMGQMHRGHMPPLSSAQQALMGTINTSMQAVQKAQIDLGEVDNLPPLGQDMASKVWIQNKMDESKHEIHSQVDAITAGTASVVNLTAGDP---TDTDYTAVGCAITTISSNLTEMSKGVKLLAALM----EDDVGGGNDLMKAARTLAGAVSDLLKAVEPASGE-----------------PRQTVLTAAGSIGQASGDLLRQIGENE---TDERFQ--DVLMNLAKAVANAAAMLV--LKAKNVA-QVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVESCIQACLSATEDGELL-KQVSAAASVVSQALADLLQH--VRQYTSRGEPIGRYDQATDTIMTVTESIFISMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKLINRLENAAKQAAAAATQTIAAAQNAAASNKNTAAHQQLVQSCKAVADHI-PQLVQGVRSSQAKPEDLSAQLALIIASQNFLQPGSKMVTSAKSSVPTVTDQAAAMQLGQCAKNLATCLAELRTAAQKAHEACGPMEIDSALTA----IQTLRSELQDAKLAATTTQLKPLPGESLEKCAQDLGSTSKSVGSSMAQLLTCAAQGNEHFT-------GI------AARETAQALKTLAQAARGVAASITDPKASAAMLDSARDVMEGSALLIHEAKQAL----ISPADAESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALKSIGEASKKLLMDAIP---PAN--KSFQEAQNELNQTAADLNQSAGEVVTATRGSSSQLAVASGKFSHDFDEFLDAGIEMAGHTQKKDDQVQVISNLKNISMASS-----KLLLAAKSLSVDPAAANAKNLLAAAARAVTDSINQLITLCTQQAP-GQKECDNALRELEAVRGML--DNPSEPVNDLSYFDCIESVMENSKVLGESMAGISQNCKISDVTAFGDSVGSASKALCGLTEAAGQASYLVGVSDPNSQAGHQGLV-DPIQFAKANQAIQMA--CQNLVDPESSPSQVLSAATIVAKHTSALCNACRLASSKTTNPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEENRSRCQVATTPLIEAVENLTTFA-----SNPEFASVPAQISNEGSAAQEPIIQSARSMLDSSTLLLKTARSLALNPKDPPTWSVLAGHSRTVSDSIKSLITAIRDKAPGQRECDSSIDNINKCIRDIEQASLAVVS------QNLPSRDDISLEALQEQLTSTVQEIGHLIDPVST--AARGEASQLGHKVTQLAGYFEPLIKASVGVASKLNDHQQQMTFLDQTKTLAESALQMLYAAKEGGGNPKASHTHDAIAEAAQLMKEAVDDIMVTLNEAASEVGMVGGMVESIAEAMAKLDE--GTPPEDEGSFVDYQTSMVKH----------SKAIAVT--AQEMMTKSVTSPDELGALA-----------SQVTVDYSQL--AVQGRLASHTAEPEEIGFQIKTRVQELGHGCIYLVQKAGALQISPTDSFTKRELIECARAVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMF-----ASAGTLNAENDE----SFADHRENILKTAKALVEDTKMLVSGAASGQERLAQAAQSSAKTITQLTDVVKLGAASIGSDDP------------ETQVVLINAVKDVAKALAELISATKCAAGKAAD-DPSMYQLKSAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQEMALFQS-------------KDSPY---------------KTTTPEEFIRMTKGITMATAKAVAAGNSARQEDIIHTANLSRKAISDMLTTCK--------------QAAFH---PEVS-------EDVRTRALRFGVECTTGYIELLEQVLLVLLRPSPE------QKQQLAASSKRVACAVTELIHTAEAMKGSEWVDPEDPT---VIAETELLGAAASIEAAAKKLEQLKPRAKPKQ-ADETLNFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGAIPANAV---DDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQVAGNAVKKASDNLVRAAQKAAFDKADEDNVVVKT------KFVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQ 2434
BLAST of Talin vs. Ensembl Medaka
Match: tln2b (talin 2 [Source:NCBI gene;Acc:101167954]) HSP 1 Score: 659.062 bits (1699), Expect = 0.000e+0 Identity = 550/1881 (29.24%), Postives = 983/1881 (52.26%), Query Frame = 3
Query: 75 TLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTM-TLKRGKTQI-RDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASR-LLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHL----IINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTR--ASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNL-THSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQQ--QLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHA-SVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTK-ACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMV 5675
+L+I + N +++ + T VYD CR + +R+P+ + ++GLF+SD D + WL++ + + YY L + + +L +K + R I+ +D T KT+ VDDSK++ EL++ IC+++GI+N+EEYS+I EL E+++ + TL++ +T + RD K+EK+K KL TDD+LNWL H +T R+ G++E + LLLRRK+F+SDQNVD+RDP+QLNLLYVQ ++ II+G+HPV+ ++A + AGIQ Q + G K K +LKEFLPKEY+K +G +KK+ +++ ++ + KV Y +L RSL+TYG++FFLVKEK++ KNKLVPRL+GI+KE VMRVDEKTK+++Q WPLTTV+R+AA+ F+LDFG+Y + Y +QTTEGE+I+QLI GYIDII+KK+++KD+ + +EE+ M+EE+V+P ++ ++ F E S+A LP G++ G +G + Q Q K + LS ++ALM I +++ ++ A DL + LG+D +SR + + +D +K + + ++T T +++ + + DY + AI TI N ++ + ++ + + D+E +G L+ AA+ L A DLL + +P E + ++ A +G+AS LL H+ E +D ++Q DTL+ AK +AN + +V +K +VA + + T Q +I AA +TS L++ KVV+ +I P+ Q+QL + + V SV+ ++ + + ++ +Q+ ++ +++ L QH+ D ++ +E + ++G++ EMV QA++LA+A ++L + + S + + +D D ++L+ AA+ L DA ++V A K E + QQ L +AA + + A I+++L LE A +Q A A Q + ++Q AA + + AS+ Q+ + + + + P+++ + P + Q L+ A Q +Q +++ S+++ P V D + L +N T LA+L+ Q+A P + + +QTL + A SV +L PLPGET+E + +GS+SKA +L N + + G+ +A+E +++ L + ARG+AA + + + + V++ +I + + A + L + + ++ V +P +++D L+S E K +++ P +KS + Q++ A N + G++++S+ T L + + ++ D L G+++ + + Q+ LK++S S+ LL K L G+++ L AA V++S+N L++ C + Q+ C+++ R+LEA++ L + P+ PIN SY C++SV E S+ L M I CKTGD F ++ + S + + ++ QA+Y +G+ N S + +PI + A +N + ASS + + AT + S++C + + +S+P + + + + K VA T NL+KTI S EN + A +L VE L A P A I+ +G AQ I +++ M++ S L+ A +LV + K P+ + +T + L ++ APGQRE + + + +R++++A++ +V ++ + + + S+ + +++ S++++ + I P+ + + + LG V + SY P+ +S LA L + + +++ TKT+ E+ L M+
Sbjct: 5 SLKICVRQCNVVKTMQFEPSTPVYDACRIIRERVPEAQTGQASDYGLFLSDDDPRKGIWLESGRTLDYYMLRNGD-ILEYKKKQRPQKIKMLDGTIKTVMVDDSKTVGELLVTICSRIGITNYEEYSVIQELTEDKKDDGLGTLRKDRTLLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVEESETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDIINGSHPVSFDKACEFAGIQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKKVFQEHKNCGEMTEIEGKVKYVKLARSLQTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKDVVQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDHFGLEGDEESTMLEESVSPKRSTILQQQF--NRVGRVEHGSVA----LP-----GIIRSGSIGGPDTFNMGTMPSAQQQITTGQMHKGHMPPLSLAQQALMGTINSSMQAVQQAQADLGHVDNLPPLGHDLASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGEP---AETDYTAVGCAITTISSNLTEMSKGVKLLAAL---MDDEVGSGHKLMGAARMLAGAVSDLLRSVEPAAAE-----------------PRQTVLTAAGSIGQASGDLLRHMGEGE----TDEKFQ--DTLMNLAKAVANAAAMLV--LKAKNVA-QVAEDTTLQNRVIAAATQCALSTSQLVACTKVVSPTISSPVCQEQLVEAGKLVDRSVETCVKACRSASDDGELL-KQVAAAAGVVSQALSDLLQHVRHYASCGEPIGRYDQATDTIMNVTENIFTSMGDAGEMVRQARVLAQATSDLVNAMR------------SDAEAEVDVDNSKKLLAAAKLLADATARMVEAAKGAAAYPENE-DQQQRLREAAEGLRVATNAAAQNAIKKKLVNRLEIAAKQAAAAATQTIAAAQNAAISNKNTASHQQLVHSCKAVADSI-PQLVQGIRSSQAQPEELGPQLTLIMASQNFLQPGSKMVSSAKSAVPTVADQAAAMQLGQCAKNLATCLAELRTATQKAHEACGPLEIDSALKT----VQTLKCELQDAKISVIDAQLKPLPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYT-------GV------AARETAQALRTLAQAARGVAACTKEPQAAAAMLDSAQCVMEGSAMLIHEAHQAL----VHPGDADSQQRLAQVAKAVSHSLNNCVNCLPGQKDVDM---ALRSIGEASKKLLVDFLPPC-----SKSFQEAQTDLNHTAAELNHSAGEVVHSSRGTSRQLAAASGKFSQDFDEFLDAGIEMAGHTQSKEDKIQVIGNLKNISMASSKLLLAAKSLSVDPGAANAK---NLLAVAARAVTESVNQLITLC-TQQAAGQKECDNALRELEAVRG--LLDNPNEPINELSYFDCIESVMENSKVLGESMAGISQHCKTGDVQAFGESVSLASKALCGLTEAAGQASYLVGVSDPN-SQSGHEGLVDPIQFARAHQAIQTACQNLVDPASSPSQVLSA---ATIVAKHTSALCNACRLASSKTSNPVARRQFVQSAKEVANTTANLVKTIKGLDGDFSEENRNRCRLATAPLLEAVENLATFAN-NPEFVSAPAQISNEGSAAQEPIVRSARSMLDSSTYLIETARSLVLNPKDPPSWSILAGHSRTVSDSIKSLITSIRDKAPGQRECDYSIDNINKCIRDIEQASL--AAVGQT--LPCRDDISMEALQEQLTSSVQEIGHLIDPVST--TARGEAAQLGHKVTQLASYFDPLIVASVGLASKLQDHQQQMTILDQTKTLSESALQML 1780 HSP 2 Score: 280.026 bits (715), Expect = 9.190e-75 Identity = 219/628 (34.87%), Postives = 329/628 (52.39%), Query Frame = 3
Query: 6180 VGQSCMDLIR------------YDQKEFIGQVRS---RLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENW-IPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLV-------HHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQ-NETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQ 7991
+G C+ L++ + ++E I RS +++ ++ LQ+ ++GTQ CI AA++V+ ++ADLDT I+FA +G+ +N EN++ S A +E I K K+LV D + +V QE LA A ++ + QL VK LG + M E Q +L+NAVRDVA AL + TK D + LK + + MV +V L+K+VK++ED RGTRALE ++E +++E ++ IP+ K S E + MTK + +A+ KA+AA + +QED++ AN+ RKAI+D++ HH V +E +SK + SE G +K L + + L + E K Q+ + S+ +A S+ E+ ++A +K + D EDP IAENEL AA+ IE AAKK+ LKPR K+ E F+ QI+ A SI +ATS LVK AS +Q+ELV+QG++ N++ ++ QWS GLISAAR+VAAAT NL ++A A VQG ++LIS++KQVAA TA LL+AC+VK+D DS+ +RLQ
Sbjct: 1837 LGHGCIFLVQKAGALQLSPTDSFSKRELIECARSVTEKVSLVLSALQAGNKGTQACITAASAVSGIIADLDTTIMFASAGT-----LNPENEE----SFADHRESILKTAKALVEDTKLLVAGAASTQEKLAQAAHSSAKTITQLTEVVK------------LGATSMGSENPETQVVLINAVRDVAKALAELIGATKCAAGKPPD-DPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIPE-----------------------------KSTSPEEFIRMTKGITIATAKAVAAGNSAQQEDVIATANLSRKAISDMLTTCKQAAHHPDVG-----EELRSKALQYSSECT-------------------------NGYIKLLEQVLQVLQRPTPE------QKQQLAVHSKHVAASVTELIQTAEAMKGSECVDPEDPT---VIAENELFGAAASIEAAAKKLEQLKPRAKPKQ-ADESLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKV--GSNLANAVDDGQWSQGLISAARMVAAATSNLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADHDSEAMRRLQ 2371
BLAST of Talin vs. Planmine SMEST
Match: SMESG000072542.1 (SMESG000072542.1) HSP 1 Score: 5420.9 bits (14061), Expect = 0.000e+0 Identity = 2721/2728 (99.74%), Postives = 2724/2728 (99.85%), Query Frame = 3
Query: 69 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYEKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDPNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHPELFGGDKE 8252
MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYIDIIIKKQKAKDNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEQPLSQQQLHASAQQVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLS+AALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIAN+EDGQLQTLHSWMDTAAESVARGELYPLPGETIESVSAIIGSSSKAASKIFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLY+KQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQQQLTSGLKSVSNNSTDLLDHLKLLLAASGSSDVNLLKQSLLKAASLVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEAT NLIKTINSCSRSE VENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKM DVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFAGSGSLALSLINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQED NSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHPELFGGDKE
Sbjct: 1 MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPLGDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYELDENERMKTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKTKGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYSDENYVIQTTEGEKIAQLIGGYIDIIIKKQKAKDNLSADAEEETAMIEENVAPSKANVISHNFIDKNTLSFEKNSLATIGHLPNRGDIGVVSQGRVGSAQPIAIRNDSKIGQGNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQHDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNSISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEQPLSQQQLHASAQQVIDSVDNVIQLVQPLIETHSVIYQQLDETVAMICESIDKLKQHLIINSITAHQDPLVTKFLSASERLPAAIGNSLEMVTQAQILAEAGTELADCLSSAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMTAGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANMEDGQLQTLHSWMDTAAESVARGELYPLPGETIESVSAIIGSSSKAASKIFDKLYNNLPDLNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAALKSKTDSNENLYQKQIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINSNLTHSALTLLAKQLNESHDCMLMTGLQLIAEVPNNQQQLTSGLKSVSNNSTDLLDHLKLLLAASGSSDVNLLKQSLLKAASLVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCMQSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATANLIKTINSCSRSELVENDEWTKACEGVLNTVEQLTQIAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHSRDRGEVIELTKTVLEAFLAMVQECETLSTTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTDNSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMTDVNYPFKKLVHDYDSLVTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIRYDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFAGSGSLALSLINSENDQNKPNSVAQIKEDIFKITKSLVSDLQKMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTLENWIPDGEDVLNSKIQEGEYSQINVGVDNVTASSDKIYSVENLVLMTKPLILASQKAMAAVQTFKQEDILMAANVGRKAITDLVHHIRVTIDMKLKEEKSKPSRIFSEKAPIVSDPDRRTVESVKENSMKIVEHGKGAVKALIDMYENLNKSVAEGKKNESHKMQMTLASRRIAHSIHEITESATQLKDTHLADQEDLNSHCAIAENELLEAASQIETAAKKIALLKPRKSIKKDTGEEYTFDGQIIVACGSIVSATSHLVKMASLSQQELVSQGRLKPSENISEQNETQWSHGLISAARLVAAATENLSDSAKAVVQGKCGTDRLISASKQVAAGTAHLLLACQVKSDADSKTNQRLQAAGSAVKRATEALVKEATEHRDVQDGSIPYTYDGPNKSMVNSMRNVIQAQADIVAKERELEMLRNKYQSIRQGHISTHPELFGGDKE 2728
BLAST of Talin vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 687.952 bits (1774), Expect = 0.000e+0 Identity = 673/2401 (28.03%), Postives = 1217/2401 (50.69%), Query Frame = 3
Query: 78 LRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERM-KTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKT-KGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYS-DENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDK-NTLSFEKNSLATIGHLPN-------RGDIGVVSQ-GRVGSAQPIAI-RNDSKIGQ-----GNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQ-------HDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNS--------------ISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIE-----THSVIYQQLDETVA-MICESIDKLKQHLIINSITAHQDPLVTKFLSASERL---PAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMT-AGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPD----LNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAAL----KSKTDSNENLYEK--QIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINS---NLTHSALTLLAKQLNESHD-----CMLMTGLQL------IAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCM-----QSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQ-IAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHS----RDRGEVIELTKTVLEAFLAMVQECETL-----------STTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTD-NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSL---VTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR-------------YDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQ-------KMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTL 6914
LRI IV + T + LD + ++ +C + K I + + + +GL++ D + WLDNSK + +Y L GD + +++R R L IRTMD T KTL+VDDS +++EL+L +C K+GI N++EYSLI + +D + + KT+++K G + +D +KL+K+K+K T+D LNWL ++LRQ GI+E + LLL+RKYFFSD NVD+RDPIQL+LLY QLK+A+I+GTHPV + EAI+LAG+QCQ +LGN + DK K +L+E LPKEY K K ++KKI Q+ K S+ + K Y LCRS KTYGITFFLVKEKV KNKL+PRL+G++KE V++VDEKTKE+I WPLT++R++AA+ + F++DFG+YS DE Y QT +GE+I+QLI GYIDII+K++KAKD+L DA+EE+ M EEN+APSKA ++ H K +++S E + H+ N + V SQ G + I + R S +G+ ++ +++ D ++ +I + DNL ++ + L + ++G DE+S+ + +D ++ R+ + +M A +L Q ++E+ + + ++ + + I + L+E IR + +ED++G LI AAK L +AF +L+ A+ P + +K + + K + +A N VGEAS LL I+ ++N I++ + ++ LL AK +AN + ++K VK +V E + Q ++ AA +G A S LIS K+VA +IE +Q+I S+++V + +Q ++E T S Q L A + E++D L +HL + ++ + FL A E + + + ++V+ A+ LA+A T + + A+ + + + + RL+ AA+ L +A L+ + K C + ++ + + L +A V + T I++++ L A R+ A T L+ +S AAK +RASN+++C++ +E++ + +I+A + R +P D AQ L+ AC+ I EQL +S++ + P V DPS+Q+ALN S+ S + +LK+CV QAD + + ++ A +E QL+ L + + S+ R L PLP E + +A++ S + + ++ N+L ++S +N+ + A+EL ++++L+ ARG+AA ++++N+ EK Q+ +++ + +++ D++ K + +D +++ ++ + + + +P +++D L ++S F +N + P+ +N N S+ +SE T FNQ + +L+++ NL + K++ S+D C ++ + + +N+ + +G+ +S + LLD +K + + V + L +A ++ DSIN LL+ ++ L Q+ C+ + +LE+++ L + P PI++ Y +C+ ++V+ L++SL K IP A K ++ F +I + S +L+ Q Y +G+ + I + S +Q +S+NC ++ + + + A I + +C+ K + S P+ + KL D K A L+ + + +++ + +N + ++ G V + V +L Q + Y + A+ I+E+ +++Q I A I +++ + +++ + AL+ + A+ + K + L L + +K SAPGQ+E E L ++++ + M + S+ +++ +S S +Q +L Q+ + I L RA + LA I L + + +S ++ ++I+ + LE +A+++ E L + + + E + C+DL+ +D I+ G + ++ +I KS+A++ E+ + P + S + D D N+L DIS EST+R+ A L+QN L YD L G + +S N +G+ +L++CV VG+ + L++ + + ++ R+ D++ LL S++ GTQ C A + E+ +D+DT+ILF + S + QN +KE +FK +++ V D K+++S D N+ + A+Q+ A+ S +LA N +GL ++ LL + ++V V+L+ F + N + + NLK + + ++ L+K +KS++D + +A++ ++ + + L
Sbjct: 20 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGD---TIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYP-------------VEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAV---EAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIE-------QSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKD---FDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKT----------PEERDRLINAAKQLAEATTVLIDSAKNCTMDKDE-MNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQI-SNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLS--AALE--QLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRL---PIQQNNNINLSNC--RSELTDTTFDFNQAVNELVSAPSFNLVNKG----CKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVR---KQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPIL--DNPVHPISHKDYFECLDFIIDKTVQPLADSL----KNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHT---SFLQIQKEISENCQTICNPDTTARQMISTAGQIAENSRKLCEASKTIM--ISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAI--ISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMK--IMKHRSRTISRTFESEESYQNILQSALIQMPHCINE-------------LSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQES-AIIP-----EKSRFGNSQSKMLDICYDMNNLTTDISSN--ANSESTQRLLAP-----LTQN-----------LTQRYDDLCRACQGAVATLS----NENNGK-QLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILF----------VKSADIQNDDREYYSVKE-LFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQES------ADQI--AITSQSLA---NDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVAR-NTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECL 2283
BLAST of Talin vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0 Identity = 673/2401 (28.03%), Postives = 1217/2401 (50.69%), Query Frame = 3
Query: 78 LRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERM-KTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKT-KGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYS-DENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDK-NTLSFEKNSLATIGHLPN-------RGDIGVVSQ-GRVGSAQPIAI-RNDSKIGQ-----GNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQ-------HDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNS--------------ISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIE-----THSVIYQQLDETVA-MICESIDKLKQHLIINSITAHQDPLVTKFLSASERL---PAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMT-AGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPD----LNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAAL----KSKTDSNENLYEK--QIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINS---NLTHSALTLLAKQLNESHD-----CMLMTGLQL------IAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCM-----QSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQ-IAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHS----RDRGEVIELTKTVLEAFLAMVQECETL-----------STTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTD-NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSL---VTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR-------------YDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQ-------KMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTL 6914
LRI IV + T + LD + ++ +C + K I + + + +GL++ D + WLDNSK + +Y L GD + +++R R L IRTMD T KTL+VDDS +++EL+L +C K+GI N++EYSLI + +D + + KT+++K G + +D +KL+K+K+K T+D LNWL ++LRQ GI+E + LLL+RKYFFSD NVD+RDPIQL+LLY QLK+A+I+GTHPV + EAI+LAG+QCQ +LGN + DK K +L+E LPKEY K K ++KKI Q+ K S+ + K Y LCRS KTYGITFFLVKEKV KNKL+PRL+G++KE V++VDEKTKE+I WPLT++R++AA+ + F++DFG+YS DE Y QT +GE+I+QLI GYIDII+K++KAKD+L DA+EE+ M EEN+APSKA ++ H K +++S E + H+ N + V SQ G + I + R S +G+ ++ +++ D ++ +I + DNL ++ + L + ++G DE+S+ + +D ++ R+ + +M A +L Q ++E+ + + ++ + + I + L+E IR + +ED++G LI AAK L +AF +L+ A+ P + +K + + K + +A N VGEAS LL I+ ++N I++ + ++ LL AK +AN + ++K VK +V E + Q ++ AA +G A S LIS K+VA +IE +Q+I S+++V + +Q ++E T S Q L A + E++D L +HL + ++ + FL A E + + + ++V+ A+ LA+A T + + A+ + + + + RL+ AA+ L +A L+ + K C + ++ + + L +A V + T I++++ L A R+ A T L+ +S AAK +RASN+++C++ +E++ + +I+A + R +P D AQ L+ AC+ I EQL +S++ + P V DPS+Q+ALN S+ S + +LK+CV QAD + + ++ A +E QL+ L + + S+ R L PLP E + +A++ S + + ++ N+L ++S +N+ + A+EL ++++L+ ARG+AA ++++N+ EK Q+ +++ + +++ D++ K + +D +++ ++ + + + +P +++D L ++S F +N + P+ +N N S+ +SE T FNQ + +L+++ NL + K++ S+D C ++ + + +N+ + +G+ +S + LLD +K + + V + L +A ++ DSIN LL+ ++ L Q+ C+ + +LE+++ L + P PI++ Y +C+ ++V+ L++SL K IP A K ++ F +I + S +L+ Q Y +G+ + I + S +Q +S+NC ++ + + + A I + +C+ K + S P+ + KL D K A L+ + + +++ + +N + ++ G V + V +L Q + Y + A+ I+E+ +++Q I A I +++ + +++ + AL+ + A+ + K + L L + +K SAPGQ+E E L ++++ + M + S+ +++ +S S +Q +L Q+ + I L RA + LA I L + + +S ++ ++I+ + LE +A+++ E L + + + E + C+DL+ +D I+ G + ++ +I KS+A++ E+ + P + S + D D N+L DIS EST+R+ A L+QN L YD L G + +S N +G+ +L++CV VG+ + L++ + + ++ R+ D++ LL S++ GTQ C A + E+ +D+DT+ILF + S + QN +KE +FK +++ V D K+++S D N+ + A+Q+ A+ S +LA N +GL ++ LL + ++V V+L+ F + N + + NLK + + ++ L+K +KS++D + +A++ ++ + + L
Sbjct: 10 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGD---TIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYP-------------VEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAV---EAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIE-------QSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKD---FDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKT----------PEERDRLINAAKQLAEATTVLIDSAKNCTMDKDE-MNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQI-SNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLS--AALE--QLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRL---PIQQNNNINLSNC--RSELTDTTFDFNQAVNELVSAPSFNLVNKG----CKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVR---KQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPIL--DNPVHPISHKDYFECLDFIIDKTVQPLADSL----KNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHT---SFLQIQKEISENCQTICNPDTTARQMISTAGQIAENSRKLCEASKTIM--ISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAI--ISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMK--IMKHRSRTISRTFESEESYQNILQSALIQMPHCINE-------------LSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQES-AIIP-----EKSRFGNSQSKMLDICYDMNNLTTDISSN--ANSESTQRLLAP-----LTQN-----------LTQRYDDLCRACQGAVATLS----NENNGK-QLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILF----------VKSADIQNDDREYYSVKE-LFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQES------ADQI--AITSQSLA---NDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVAR-NTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECL 2273
BLAST of Talin vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0 Identity = 673/2401 (28.03%), Postives = 1217/2401 (50.69%), Query Frame = 3
Query: 78 LRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERM-KTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKT-KGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYS-DENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDK-NTLSFEKNSLATIGHLPN-------RGDIGVVSQ-GRVGSAQPIAI-RNDSKIGQ-----GNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQ-------HDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNS--------------ISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIE-----THSVIYQQLDETVA-MICESIDKLKQHLIINSITAHQDPLVTKFLSASERL---PAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMT-AGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPD----LNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAAL----KSKTDSNENLYEK--QIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINS---NLTHSALTLLAKQLNESHD-----CMLMTGLQL------IAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCM-----QSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQ-IAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHS----RDRGEVIELTKTVLEAFLAMVQECETL-----------STTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTD-NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSL---VTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR-------------YDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQ-------KMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTL 6914
LRI IV + T + LD + ++ +C + K I + + + +GL++ D + WLDNSK + +Y L GD + +++R R L IRTMD T KTL+VDDS +++EL+L +C K+GI N++EYSLI + +D + + KT+++K G + +D +KL+K+K+K T+D LNWL ++LRQ GI+E + LLL+RKYFFSD NVD+RDPIQL+LLY QLK+A+I+GTHPV + EAI+LAG+QCQ +LGN + DK K +L+E LPKEY K K ++KKI Q+ K S+ + K Y LCRS KTYGITFFLVKEKV KNKL+PRL+G++KE V++VDEKTKE+I WPLT++R++AA+ + F++DFG+YS DE Y QT +GE+I+QLI GYIDII+K++KAKD+L DA+EE+ M EEN+APSKA ++ H K +++S E + H+ N + V SQ G + I + R S +G+ ++ +++ D ++ +I + DNL ++ + L + ++G DE+S+ + +D ++ R+ + +M A +L Q ++E+ + + ++ + + I + L+E IR + +ED++G LI AAK L +AF +L+ A+ P + +K + + K + +A N VGEAS LL I+ ++N I++ + ++ LL AK +AN + ++K VK +V E + Q ++ AA +G A S LIS K+VA +IE +Q+I S+++V + +Q ++E T S Q L A + E++D L +HL + ++ + FL A E + + + ++V+ A+ LA+A T + + A+ + + + + RL+ AA+ L +A L+ + K C + ++ + + L +A V + T I++++ L A R+ A T L+ +S AAK +RASN+++C++ +E++ + +I+A + R +P D AQ L+ AC+ I EQL +S++ + P V DPS+Q+ALN S+ S + +LK+CV QAD + + ++ A +E QL+ L + + S+ R L PLP E + +A++ S + + ++ N+L ++S +N+ + A+EL ++++L+ ARG+AA ++++N+ EK Q+ +++ + +++ D++ K + +D +++ ++ + + + +P +++D L ++S F +N + P+ +N N S+ +SE T FNQ + +L+++ NL + K++ S+D C ++ + + +N+ + +G+ +S + LLD +K + + V + L +A ++ DSIN LL+ ++ L Q+ C+ + +LE+++ L + P PI++ Y +C+ ++V+ L++SL K IP A K ++ F +I + S +L+ Q Y +G+ + I + S +Q +S+NC ++ + + + A I + +C+ K + S P+ + KL D K A L+ + + +++ + +N + ++ G V + V +L Q + Y + A+ I+E+ +++Q I A I +++ + +++ + AL+ + A+ + K + L L + +K SAPGQ+E E L ++++ + M + S+ +++ +S S +Q +L Q+ + I L RA + LA I L + + +S ++ ++I+ + LE +A+++ E L + + + E + C+DL+ +D I+ G + ++ +I KS+A++ E+ + P + S + D D N+L DIS EST+R+ A L+QN L YD L G + +S N +G+ +L++CV VG+ + L++ + + ++ R+ D++ LL S++ GTQ C A + E+ +D+DT+ILF + S + QN +KE +FK +++ V D K+++S D N+ + A+Q+ A+ S +LA N +GL ++ LL + ++V V+L+ F + N + + NLK + + ++ L+K +KS++D + +A++ ++ + + L
Sbjct: 20 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGD---TIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYP-------------VEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAV---EAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIE-------QSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKD---FDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKT----------PEERDRLINAAKQLAEATTVLIDSAKNCTMDKDE-MNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQI-SNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLS--AALE--QLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRL---PIQQNNNINLSNC--RSELTDTTFDFNQAVNELVSAPSFNLVNKG----CKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVR---KQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPIL--DNPVHPISHKDYFECLDFIIDKTVQPLADSL----KNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHT---SFLQIQKEISENCQTICNPDTTARQMISTAGQIAENSRKLCEASKTIM--ISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAI--ISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMK--IMKHRSRTISRTFESEESYQNILQSALIQMPHCINE-------------LSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQES-AIIP-----EKSRFGNSQSKMLDICYDMNNLTTDISSN--ANSESTQRLLAP-----LTQN-----------LTQRYDDLCRACQGAVATLS----NENNGK-QLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILF----------VKSADIQNDDREYYSVKE-LFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQES------ADQI--AITSQSLA---NDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVAR-NTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECL 2283
BLAST of Talin vs. Planmine SMEST
Match: SMESG000066444.1 (SMESG000066444.1) HSP 1 Score: 686.797 bits (1771), Expect = 0.000e+0 Identity = 673/2401 (28.03%), Postives = 1217/2401 (50.69%), Query Frame = 3
Query: 78 LRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFVSDADSMRAYWLDNSKPVSYYPL--GDKNLVLLFKSRMRRLIIRTMDDTKKTLEVDDSKSIAELILPICNKMGISNHEEYSLIYE-LDENERM-KTMTLKRGKTQIRDFDKLEKMKQKLKTDDELNWLPHGKTLRQLGIDEKDELLLRRKYFFSDQNVDARDPIQLNLLYVQLKNAIIDGTHPVNIEEAIQLAGIQCQAELGNMAPDKAKSIHSNLKEFLPKEYVKT-KGIDKKIIAQYEKLSGKSDKDVKVIYAQLCRSLKTYGITFFLVKEKVRAKNKLVPRLMGISKEYVMRVDEKTKEMIQNWPLTTVRRYAATASLFSLDFGDYS-DENYVIQTTEGEKIAQLIGGYXXXXXXXXXXXXNLSADAEEETAMIEENVAPSKANVISHNFIDK-NTLSFEKNSLATIGHLPN-------RGDIGVVSQ-GRVGSAQPIAI-RNDSKIGQ-----GNVNVQPQKFQIRDLSQPKRALMIRIGDNLKILKAATEDLDKHIEVAKLGNDESSRNYRKQTLDIAKTRVKGNLMSMTMATGNLLMMMQ-------HDEDSDDNDDYGRIDAAIATIGYNTDKLLENIRHVYEMTFETDEEDINGGNLIEAAKTLLNAFQDLLNASKPINMESDASLSDESINGEKPAFSNKALMEAVNRVGEASRLLLHIISVEQNS--------------ISDLEWQTRDTLLTDAKQIANLVSGMVKIVKEASVALKETQGTEAQAMLIHAAKNSGQATSMLISAAKVVACSIEXXXXXXXXXXXXXXVIDSVDNVIQLVQPLIE-----THSVIYQQLDETVA-MICESIDKLKQHLIINSITAHQDPLVTKFLSASERL---PAAIGNSLEMVTQAQILAEAGTELADCLSNAALVQSPQNNISQSTSSLDSDRQRRLMIAAQALTDAVGKLVHATKICVKESEQTLENQQGLMQAAHHMTSVAHMT-AGEIIRQRLSKGLEFAGRQTALTADQLVLSSQEAAKTTRASNYQICSEAQEMTEIVLPEVILACTKIRENPIDPNAQNNLLNACQKLIQNLEQLLKSSEALEPRVKDPSIQSALNISMQNSQTSLADLKQCVQQADTIFKPTRVANIANIEDGQLQTLHSWMDTAAESVARGELYPLPGETIEXXXXXXXXXXXXXXXXFDKLYNNLPD----LNNYMSDNSPENIGLQSDFIRSAKELMESMEKLLRGARGIAAL----KSKTDSNENLYEK--QIDVIDCGKQIIRSGEDVIQGIKLASIRAVAIDELKKSIDKMKEDIDELVYRIPAYQEIDCLVSKLKSSMEMFDKNIINNKPVIENANKTKSHSQIQSEFTTAVAIFNQTLGDLINS---NLTHSALTLLAKQLNESHD-----CMLMTGLQL------IAEVPNNQQQLTSGLKSVSNNSTXXXXXXXXXXAASGSSDVNXXXXXXXXXXXXVSDSINDLLSACASTLPVTQQLCESSQRQLEALKTSLLAEPPSLPINNYSYNQCM-----QSVEELSESLLTQMKRIPVACKTGDSNDFCSAIQVLSASTVDMLKSVTQANYKLGLIQSNASIRTSSTVTNPILDSLIQHASVMSKNCISMASSNNSEIPCRELATDIKSRASSVCQLVKECINNSSDPDHQNKLLDAGKRVAEATGNLIKTINSCSRSESVENDEWTKACEG-VLNTVEQLTQ-IAKYTPITNPAVKTITEQGRQAQTEIHQASIEMVEGSCSLLRAAGALVKDSKSIPANQAFIINQKTYDSCLNRLRNVVKFSAPGQREFIEMEEELKQVLRNLDRANMDQFSVNKSSKMNAKSNDSINSDIQRMQLSLKQLKNNIRPIENILSDQSKFEYLGRAVWEAGSYLAPISESSNNLAQLLPHS----RDRGEVIELTKTVLEAFLAMVQECETL-----------STTTNNQDLMENVSSLKIGCDDLMKFIDGIASCHGTLENMIASIQKSAARLTETNNVAPLDAASAHTLIFQSIKGITDTVTD-NSLNKDISVTRLQKKESTKRIKANEDNQILSQNKMADVNYPFKKLVHDYDSL---VTGVIQIMSSGAFNVQDGEDKLKKCVVAVGQSCMDLIR-------------YDQKEFIGQVRSRLTDLMYLLQSNSRGTQCCIVAANSVNEMVADLDTAILFXXXXXXXXXXINSENDQNKPNSVAQIKEDIFKITKSLVSDLQ-------KMVISVDGKQENLAMATDNAVRRANQLCGAVKSSALAIGSNPSLLGLSEMSDECISAQTLLLNAVRDVAVALVDFFNCTKMNVTATTDKERDRSNLKSSLETMVKSVDGLIKSVKSLEDSGFRGTRALETSLEAMRKEYRTL 6914
LRI IV + T + LD + ++ +C + K I + + + +GL++ D + WLDNSK + +Y L GD + +++R R L IRTMD T KTL+VDDS +++EL+L +C K+GI N++EYSLI + +D + + KT+++K G + +D +KL+K+K+K T+D LNWL ++LRQ GI+E + LLL+RKYFFSD NVD+RDPIQL+LLY QLK+A+I+GTHPV + EAI+LAG+QCQ +LGN + DK K +L+E LPKEY K K ++KKI Q+ K S+ + K Y LCRS KTYGITFFLVKEKV KNKL+PRL+G++KE V++VDEKTKE+I WPLT++R++AA+ + F++DFG+YS DE Y QT +GE+I+QLI GYIDII+K++KAKD+L DA+EE+ M EEN+APSKA ++ H K +++S E + H+ N + V SQ G + I + R S +G+ ++ +++ D ++ +I + DNL ++ + L + ++G DE+S+ + +D ++ R+ + +M A +L Q ++E+ + + ++ + + I + L+E IR + +ED++G LI AAK L +AF +L+ A+ P + +K + + K + +A N VGEAS LL I+ ++N I++ + ++ LL AK +AN + ++K VK +V E + Q ++ AA +G A S LIS K+VA +IE +Q+I S+++V + +Q ++E T S Q L A + E++D L +HL + ++ + FL A E + + + ++V+ A+ LA+A T + + A+ + + + + RL+ AA+ L +A L+ + K C + ++ + + L +A V + T I++++ L A R+ A T L+ +S AAK +RASN+++C++ +E++ + +I+A + R +P D AQ L+ AC+ I EQL +S++ + P V DPS+Q+ALN S+ S + +LK+CV QAD + + ++ A +E QL+ L + + S+ R L PLP E + +A++ S + + ++ N+L ++S +N+ + A+EL ++++L+ ARG+AA ++++N+ EK Q+ +++ + +++ D++ K + +D +++ ++ + + + +P +++D L ++S F +N + P+ +N N S+ +SE T FNQ + +L+++ NL + K++ S+D C ++ + + +N+ + +G+ +S + LLD +K + + V + L +A ++ DSIN LL+ ++ L Q+ C+ + +LE+++ L + P PI++ Y +C+ ++V+ L++SL K IP A K ++ F +I + S +L+ Q Y +G+ + I + S +Q +S+NC ++ + + + A I + +C+ K + S P+ + KL D K A L+ + + +++ + +N + ++ G V + V +L Q + Y + A+ I+E+ +++Q I A I +++ + +++ + AL+ + A+ + K + L L + +K SAPGQ+E E L ++++ + M + S+ +++ +S S +Q +L Q+ + I L RA + LA I L + + +S ++ ++I+ + LE +A+++ E L + + + E + C+DL+ +D I+ G + ++ +I KS+A++ E+ + P + S + D D N+L DIS EST+R+ A L+QN L YD L G + +S N +G+ +L++CV VG+ + L++ + + ++ R+ D++ LL S++ GTQ C A + E+ +D+DT+ILF + S + QN +KE +FK +++ V D K+++S D N+ + A+Q+ A+ S +LA N +GL ++ LL + ++V V+L+ F + N + + NLK + + ++ L+K +KS++D + +A++ ++ + + L
Sbjct: 20 LRIHIVDADVTKIVPLDPEATIFQLCETIRKNIREAQTKSPKSYGLYLPHDDLKKGLWLDNSKTLQHYILKRGD---TIEYRNRSRWLHIRTMDGTNKTLKVDDSWTVSELMLTVCTKLGIYNYDEYSLISDKMDFSPGIDKTLSMKHGISINKDQEKLDKLKKKYHTEDGLNWLNPSQSLRQQGIEESEVLLLKRKYFFSDMNVDSRDPIQLSLLYEQLKDAVINGTHPVTLPEAIELAGLQCQVQLGNYSADKFKPGFLDLRECLPKEYQKNPKTVEKKIFNQHSKSKDLSEVEAKEKYCLLCRSFKTYGITFFLVKEKVIGKNKLIPRLLGVNKESVVQVDEKTKEIINTWPLTSIRKWAASFNGFTMDFGEYSPDEYYTAQTDKGERISQLIAGYIDIILKRKKAKDHLGVDADEESIMYEENIAPSKAIIVEHVPKQKRSSVSEEDVVIRKKAHMANSSVRMNSQASDSVCSQDGTDFYQEDINMSRQTSSLGRTQSPSSSLTTNSMHYRMSDDDIRQKLYIISLQDNLDTIQKYKDQLMIENKGPEIGKDEASQQWIYVNIDNSRQRMADEIGAMNAAVAQVLRSAQGLATIEENEEEEMNEEMIAKMQNSFSLITVHLPSLMEEIRTAAYYQDQLTDEDVSGEELIAAAKRLADAFTNLIKAAYP-------------VEDQKRSLNRKEIFDAANAVGEASSDLLQQITEQENCQIELKSERPYSIIMITEEDQLYQEELLRLAKSVANETTNLIKQVKVIAV---EAENPSDQKKVVMAATETGLAISQLISTTKIVAPTIE-------QSVCQEQLIFSIEDVSKAIQVVVESSNKATQSEELQDLTVQAANQVQEALDTLMKHLRKD---FDKNDKLDNFLLAYENIQEVDDSDDDLDKLVSAARRLAQATTAMISEIQLKAVNEQYKT----------PEERDRLINAAKQLAEATTVLIDSAKNCTMDKDE-MNLRYTLREATERFIVVTYTTECATYIQEQVIDHLLVAARKAATTGTHLINTSLSAAKKSRASNFKVCNDGRELSNQI-SNLIVAIKEARRDPKDHLAQLELIAACRDYIDPSEQLSQSNKYMWPTVSDPSLQTALNQSINQSVIATEELKKCVHQADLMCQHLDLS--AALE--QLKRLEQNLKSIKNSIERENLIPLPDEKSDESAALLIKSVRRSGSAANQFKNDLESRCVVYEQTNGEDSYQNLENLDAAGQKARELSMALDRLVHAARGVAASIEFENQESENNDKNLEKLAQLQIVNNCLEAVKAARDLVIEAKSSPPDNDQMDRAQQASVRLSDALSLCLDSLPGQRDLDMLSKHIESKKHQFAENRL---PIQQNNNINLSNC--RSELTDTTFDFNQAVNELVSAPSFNLVNKG----CKKMRMSYDRIVEICNVLVHDPFDESDSALHHLSSNRDHIANGVMIMSEDCQTLLDKVKKIQCEPDNIIVR---KQLQEATKMLLDSINRLLTNISTNLRPGQKECDKTIYRLESMRPIL--DNPVHPISHKDYFECLDFIIDKTVQPLADSL----KNIPAAVKDENNQKFIDSIYHCADSVCMLLEETAQTAYLVGVGDVRSKIGNKGLADHT---SFLQIQKEISENCQTICNPDTTARQMISTAGQIAENSRKLCEASKTIM--ISFPNDKIKLSDKTKITLLAVSELMTGVQNLNQNFNEDNRKEVESLSGKVQDNVAELVQLLLSYKFAGDAAI--ISEEAKESQGPIKAAGITVLDTAIEVIQCSKALISSEANEELFIAYSSSCKDLNDALKHLISTIKESAPGQKECDEALAILAKLIKQAYDSKMK--IMKHRSRTISRTFESEESYQNILQSALIQMPHCINE-------------LSRAGKKEPEQLARIFSRQTQLLESMVNSCICAANQTDLIQNSNIYLEHLIAILEASEQLLKAIKKSGGNPKANSVHSQIDEMAQGVIESCEDLLAALDKISFKQGNVNTIVETITKSSAKVQES-AIIP-----EKSRFGNSQSKMLDICYDMNNLTTDISSN--ANSESTQRLLAP-----LTQN-----------LTQRYDDLCRACQGAVATLS----NENNGK-QLQECVQTVGKVSISLVKSTTEVRPSVASSISNLQAKTQELHKRIDDVIQLLISSNVGTQACTQAIKILKEINSDIDTSILF----------VKSADIQNDDREYYSVKE-LFKKSRNSVIDNSSELVRNIKLIVSKDVCDVNILQES------ADQI--AITSQSLA---NDVKVGLEHLNSSTSQYNIELLVSFQEVIVSLISFLEVAR-NTSELPYTDPLFQNLKEEGKCSINAITSLLKVLKSMDDVNLKDFQAIDNAIIELEHNHECL 2283 The following BLAST results are available for this feature:
BLAST of Talin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Talin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Talin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Talin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Talin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Talin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Talin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Talin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Talin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Talin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Talin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Talin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Talin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Talin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012271 ID=SMED30012271|Name=Talin|organism=Schmidtea mediterranea sexual|type=transcript|length=8430bpback to top protein sequence of SMED30012271-orf-1 >SMED30012271-orf-1 ID=SMED30012271-orf-1|Name=SMED30012271-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2729bp MHTLRILIVPTNKTISLKLDLDTVVYDICRDLFKRIPQKENLLVEEFGLFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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