Forkhead box protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012265 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Forkhead box protein vs. Ensembl Human
Match: FOXO4 (forkhead box O4 [Source:HGNC Symbol;Acc:HGNC:7139]) HSP 1 Score: 108.997 bits (271), Expect = 5.463e-25 Identity = 77/189 (40.74%), Postives = 97/189 (51.32%), Query Frame = 1 Query: 136 LDDCHSPEFRARSQTWG------GNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKIL-----PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNE-NMKSSLWSINTKCYK-----RERSNSMD 651 LD P+ R RS TW N S + E DL +K T S S + E P P IL P K SR+N WG ++Y++LI AI S P + TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH KF+K NE KSS W +N + K R R+ SMD Sbjct: 18 LDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEV-EPDLGEKVHT-EGRSEPILLPSRLPE---PAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMD 199
BLAST of Forkhead box protein vs. Ensembl Human
Match: FOXO3 (forkhead box O3 [Source:HGNC Symbol;Acc:HGNC:3821]) HSP 1 Score: 101.679 bits (252), Expect = 3.129e-22 Identity = 56/111 (50.45%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P++ TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN K R R+ SMD Sbjct: 147 PRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIINPDGGKSGKAPRRRAVSMD 255
BLAST of Forkhead box protein vs. Ensembl Human
Match: FOXO3 (forkhead box O3 [Source:HGNC Symbol;Acc:HGNC:3821]) HSP 1 Score: 101.679 bits (252), Expect = 3.129e-22 Identity = 56/111 (50.45%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P++ TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN K R R+ SMD Sbjct: 147 PRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIINPDGGKSGKAPRRRAVSMD 255
BLAST of Forkhead box protein vs. Ensembl Human
Match: FOXO6 (forkhead box O6 [Source:HGNC Symbol;Acc:HGNC:24814]) HSP 1 Score: 100.523 bits (249), Expect = 3.790e-22 Identity = 53/108 (49.07%), Postives = 72/108 (66.67%), Query Frame = 1 Query: 346 KSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 KSSR+N WG +Y+DLI AI S P++ TL QIY+++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W +N + K R R+ SMD Sbjct: 81 KSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMD 186
BLAST of Forkhead box protein vs. Ensembl Human
Match: FOXO6 (forkhead box O6 [Source:HGNC Symbol;Acc:HGNC:24814]) HSP 1 Score: 100.523 bits (249), Expect = 3.932e-22 Identity = 53/108 (49.07%), Postives = 72/108 (66.67%), Query Frame = 1 Query: 346 KSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 KSSR+N WG +Y+DLI AI S P++ TL QIY+++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W +N + K R R+ SMD Sbjct: 81 KSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMD 186
BLAST of Forkhead box protein vs. Ensembl Celegans
Match: daf-16 (Forkhead box protein O [Source:UniProtKB/Swiss-Prot;Acc:O16850]) HSP 1 Score: 97.8265 bits (242), Expect = 7.117e-22 Identity = 50/112 (44.64%), Postives = 72/112 (64.29%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-------RERSNSMDC 654 K ++R+N WG +Y++LI AI + P + TL Q+YE++ +N YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN RERSN+++ Sbjct: 31 KTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRI--QNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIET 140
BLAST of Forkhead box protein vs. Ensembl Celegans
Match: daf-16 (Forkhead box protein O [Source:UniProtKB/Swiss-Prot;Acc:O16850]) HSP 1 Score: 97.4413 bits (241), Expect = 7.389e-22 Identity = 50/112 (44.64%), Postives = 72/112 (64.29%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-------RERSNSMDC 654 K ++R+N WG +Y++LI AI + P + TL Q+YE++ +N YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN RERSN+++ Sbjct: 33 KTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRI--QNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIET 142
BLAST of Forkhead box protein vs. Ensembl Celegans
Match: daf-16 (Forkhead box protein O [Source:UniProtKB/Swiss-Prot;Acc:O16850]) HSP 1 Score: 97.4413 bits (241), Expect = 1.416e-21 Identity = 50/112 (44.64%), Postives = 72/112 (64.29%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-------RERSNSMDC 654 K ++R+N WG +Y++LI AI + P + TL Q+YE++ +N YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN RERSN+++ Sbjct: 113 KTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRI--QNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIET 222
BLAST of Forkhead box protein vs. Ensembl Celegans
Match: daf-16 (Forkhead box protein O [Source:UniProtKB/Swiss-Prot;Acc:O16850]) HSP 1 Score: 97.4413 bits (241), Expect = 1.485e-21 Identity = 50/112 (44.64%), Postives = 72/112 (64.29%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-------RERSNSMDC 654 K ++R+N WG +Y++LI AI + P + TL Q+YE++ +N YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN RERSN+++ Sbjct: 136 KTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRI--QNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIET 245
BLAST of Forkhead box protein vs. Ensembl Celegans
Match: daf-16 (Forkhead box protein O [Source:UniProtKB/Swiss-Prot;Acc:O16850]) HSP 1 Score: 97.4413 bits (241), Expect = 1.485e-21 Identity = 50/112 (44.64%), Postives = 72/112 (64.29%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-------RERSNSMDC 654 K ++R+N WG +Y++LI AI + P + TL Q+YE++ +N YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN RERSN+++ Sbjct: 136 KTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRI--QNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIET 245
BLAST of Forkhead box protein vs. Ensembl Fly
Match: foxo (gene:FBgn0038197 transcript:FBtr0082887) HSP 1 Score: 99.7525 bits (247), Expect = 5.868e-22 Identity = 69/192 (35.94%), Postives = 98/192 (51.04%), Query Frame = 1 Query: 115 SLAMNNM-----LDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK----RERSNSMDCKR 660 LAM+ + LD P+ RARS TW +E T ++ + +N + K K SSR+N WG +Y+DLI AI S ++ TL QIYE++ +N YF ++ D+ SSAGWKNSIRHNLSLH++F++ +NE KSS W +N + R R+ SM+ R Sbjct: 18 GLAMDQLGGDLPLDVGFEPQTRARSNTW---PCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAK---------KNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSR 195
BLAST of Forkhead box protein vs. Ensembl Fly
Match: foxo (gene:FBgn0038197 transcript:FBtr0082886) HSP 1 Score: 99.7525 bits (247), Expect = 5.868e-22 Identity = 69/192 (35.94%), Postives = 98/192 (51.04%), Query Frame = 1 Query: 115 SLAMNNM-----LDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK----RERSNSMDCKR 660 LAM+ + LD P+ RARS TW +E T ++ + +N + K K SSR+N WG +Y+DLI AI S ++ TL QIYE++ +N YF ++ D+ SSAGWKNSIRHNLSLH++F++ +NE KSS W +N + R R+ SM+ R Sbjct: 18 GLAMDQLGGDLPLDVGFEPQTRARSNTW---PCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAK---------KNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSR 195
BLAST of Forkhead box protein vs. Ensembl Fly
Match: foxo (gene:FBgn0038197 transcript:FBtr0346723) HSP 1 Score: 99.3673 bits (246), Expect = 7.121e-22 Identity = 69/192 (35.94%), Postives = 98/192 (51.04%), Query Frame = 1 Query: 115 SLAMNNM-----LDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK----RERSNSMDCKR 660 LAM+ + LD P+ RARS TW +E T ++ + +N + K K SSR+N WG +Y+DLI AI S ++ TL QIYE++ +N YF ++ D+ SSAGWKNSIRHNLSLH++F++ +NE KSS W +N + R R+ SM+ R Sbjct: 18 GLAMDQLGGDLPLDVGFEPQTRARSNTW---PCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAK---------KNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSR 195
BLAST of Forkhead box protein vs. Ensembl Fly
Match: foxo (gene:FBgn0038197 transcript:FBtr0337094) HSP 1 Score: 98.9821 bits (245), Expect = 8.206e-22 Identity = 69/192 (35.94%), Postives = 98/192 (51.04%), Query Frame = 1 Query: 115 SLAMNNM-----LDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK----RERSNSMDCKR 660 LAM+ + LD P+ RARS TW +E T ++ + +N + K K SSR+N WG +Y+DLI AI S ++ TL QIYE++ +N YF ++ D+ SSAGWKNSIRHNLSLH++F++ +NE KSS W +N + R R+ SM+ R Sbjct: 18 GLAMDQLGGDLPLDVGFEPQTRARSNTW---PCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAK---------KNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSR 195
BLAST of Forkhead box protein vs. Ensembl Fly
Match: foxo (gene:FBgn0038197 transcript:FBtr0305052) HSP 1 Score: 98.9821 bits (245), Expect = 8.206e-22 Identity = 69/192 (35.94%), Postives = 98/192 (51.04%), Query Frame = 1 Query: 115 SLAMNNM-----LDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK----RERSNSMDCKR 660 LAM+ + LD P+ RARS TW +E T ++ + +N + K K SSR+N WG +Y+DLI AI S ++ TL QIYE++ +N YF ++ D+ SSAGWKNSIRHNLSLH++F++ +NE KSS W +N + R R+ SM+ R Sbjct: 18 GLAMDQLGGDLPLDVGFEPQTRARSNTW---PCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAK---------KNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRV--QNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSR 195
BLAST of Forkhead box protein vs. Ensembl Zebrafish
Match: foxo4 (forkhead box O4 [Source:ZFIN;Acc:ZDB-GENE-150311-1]) HSP 1 Score: 104.375 bits (259), Expect = 2.051e-23 Identity = 62/131 (47.33%), Postives = 82/131 (62.60%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMDCKRSGVDLIARRKLLKEQRR 711 P K SSR+N WG ++Y+DLI AI + P + TL QIY+++ K YF ++ D+ SSAGWKNSIRHNLSLH+KF++ NE+ KSS W +N + K R R+ SMD SG KLLK + R Sbjct: 84 PRKGSSRRNAWGNQSYADLISQAIENSPEKRLTLAQIYDWMVKTVPYFKDKGDSNSSAGWKNSIRHNLSLHNKFLRV--HNESTGKSSWWMLNPEGGKTGKAHRRRATSMD--NSG-------KLLKSRIR 203
BLAST of Forkhead box protein vs. Ensembl Zebrafish
Match: foxo4 (forkhead box O4 [Source:ZFIN;Acc:ZDB-GENE-150311-1]) HSP 1 Score: 104.375 bits (259), Expect = 2.051e-23 Identity = 62/131 (47.33%), Postives = 82/131 (62.60%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMDCKRSGVDLIARRKLLKEQRR 711 P K SSR+N WG ++Y+DLI AI + P + TL QIY+++ K YF ++ D+ SSAGWKNSIRHNLSLH+KF++ NE+ KSS W +N + K R R+ SMD SG KLLK + R Sbjct: 84 PRKGSSRRNAWGNQSYADLISQAIENSPEKRLTLAQIYDWMVKTVPYFKDKGDSNSSAGWKNSIRHNLSLHNKFLRV--HNESTGKSSWWMLNPEGGKTGKAHRRRATSMD--NSG-------KLLKSRIR 203
BLAST of Forkhead box protein vs. Ensembl Zebrafish
Match: foxo3a (forkhead box O3A [Source:ZFIN;Acc:ZDB-GENE-050116-1]) HSP 1 Score: 103.99 bits (258), Expect = 2.817e-23 Identity = 56/125 (44.80%), Postives = 77/125 (61.60%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQR 708 P K S+R+N WG +Y+DLI AI S P + TL QIY+++ +N YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N K ++ +R V + KL+K R Sbjct: 130 PRKSSARRNAWGNYSYADLITQAIESSPEKRLTLAQIYDWMVRNVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMVNPDGGKGGKA----PRRRAVSMDNSNKLIKSAR 248
BLAST of Forkhead box protein vs. Ensembl Zebrafish
Match: foxo1b (forkhead box O1 b [Source:NCBI gene;Acc:567969]) HSP 1 Score: 103.219 bits (256), Expect = 5.661e-23 Identity = 55/107 (51.40%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIYE++ K+ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N + K R R+ SMD Sbjct: 130 SSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMLNPEGGKSGKSPRRRATSMD 234
BLAST of Forkhead box protein vs. Ensembl Zebrafish
Match: foxo6a (forkhead box O6 a [Source:ZFIN;Acc:ZDB-GENE-110914-126]) HSP 1 Score: 102.834 bits (255), Expect = 7.155e-23 Identity = 66/173 (38.15%), Postives = 96/173 (55.49%), Query Frame = 1 Query: 166 ARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPA-----KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 ARS +W N + ++ ADLS + F DS + S + + + A K SSR+N WG ++Y++LI AI S P++ TL QIY+++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W +N + K R R+ SMD Sbjct: 23 ARSCSW---TNDFSCDVVNADLSLNLSIFQVDSDRAPSPSCRRRMMVLDAGGFHDLTGAALRKTKASSRRNAWGNQSYAELITRAIESTPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGKLGKSQRRRAVSMD 190
BLAST of Forkhead box protein vs. Ensembl Xenopus
Match: FOXO4 (forkhead box O4 [Source:NCBI gene;Acc:100492831]) HSP 1 Score: 103.219 bits (256), Expect = 4.521e-23 Identity = 55/111 (49.55%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNE-NMKSSLWSINTKCYK-----RERSNSMD 651 P K SR+N WG ++Y++LI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH KF+K NE KSS W +N + K R R+ SMD Sbjct: 77 PRKGGSRRNAWGNQSYAELISQAIESSPEKRLTLSQIYDWMVKSIPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMD 185
BLAST of Forkhead box protein vs. Ensembl Xenopus
Match: FOXO4 (forkhead box O4 [Source:NCBI gene;Acc:100492831]) HSP 1 Score: 103.219 bits (256), Expect = 4.883e-23 Identity = 55/111 (49.55%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNE-NMKSSLWSINTKCYK-----RERSNSMD 651 P K SR+N WG ++Y++LI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH KF+K NE KSS W +N + K R R+ SMD Sbjct: 77 PRKGGSRRNAWGNQSYAELISQAIESSPEKRLTLSQIYDWMVKSIPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMD 185
BLAST of Forkhead box protein vs. Ensembl Xenopus
Match: foxo1 (forkhead box O1 [Source:NCBI gene;Acc:493378]) HSP 1 Score: 101.679 bits (252), Expect = 2.469e-22 Identity = 55/107 (51.40%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH KFV+ +NE KSS W +N + K R R+ SMD Sbjct: 138 SSRRNAWGNLSYADLISQAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFVRV--QNEGTGKSSWWILNPEGGKNGKSPRRRAASMD 242
BLAST of Forkhead box protein vs. Ensembl Xenopus
Match: c2cd4c (C2 calcium-dependent domain containing 4C [Source:Xenbase;Acc:XB-GENE-5998006]) HSP 1 Score: 98.5969 bits (244), Expect = 1.706e-21 Identity = 53/108 (49.07%), Postives = 71/108 (65.74%), Query Frame = 1 Query: 346 KSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 KSSR+N WG +Y+DLI AI S P + TL QIY+++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W +N + K R R+ SMD Sbjct: 48 KSSRRNAWGNLSYADLITKAIESSPERRLTLSQIYDWMVRFVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGKTGKTPRRRAASMD 153
BLAST of Forkhead box protein vs. Ensembl Xenopus
Match: foxo3 (forkhead box O3 [Source:NCBI gene;Acc:100125025]) HSP 1 Score: 97.0561 bits (240), Expect = 8.635e-21 Identity = 53/109 (48.62%), Postives = 72/109 (66.06%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNEN-MKSSLWSINTKCYK-----RERSNSMD 651 K SSR+N WG +Y+DLI AI S ++ TL QIY+++ ++ YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN + K R R+ SMD Sbjct: 130 KCSSRRNAWGNMSYADLITRAIESSQDKRLTLSQIYDWMVRSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFIRV--QNEGSGKSSWWMINPEGGKGGKAPRRRAVSMD 236
BLAST of Forkhead box protein vs. Ensembl Mouse
Match: Foxo4 (forkhead box O4 [Source:MGI Symbol;Acc:MGI:1891915]) HSP 1 Score: 107.842 bits (268), Expect = 9.542e-25 Identity = 75/188 (39.89%), Postives = 94/188 (50.00%), Query Frame = 1 Query: 136 LDDCHSPEFRARSQTWGGN-----DNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKIL-----PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNE-NMKSSLWSINTKCYK-----RERSNSMD 651 LD P+ R RS TW + +E L QK T S S + E P P IL P K SR+N WG ++Y++LI AI S P + TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH KF+K NE KSS W +N K R R+ SMD Sbjct: 18 LDPDFEPQSRPRSCTWPLPRPDLATEPHEPSEVEPSLGQKVPT-EGHSEPILLPSRLPE---PAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPDGGKGGKAPRRRAASMD 199
BLAST of Forkhead box protein vs. Ensembl Mouse
Match: Foxo3 (forkhead box O3 [Source:MGI Symbol;Acc:MGI:1890081]) HSP 1 Score: 101.679 bits (252), Expect = 1.977e-22 Identity = 56/111 (50.45%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P++ TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN K R R+ SMD Sbjct: 146 PRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIINPDGGKSGKAPRRRAVSMD 254
BLAST of Forkhead box protein vs. Ensembl Mouse
Match: Foxo3 (forkhead box O3 [Source:MGI Symbol;Acc:MGI:1890081]) HSP 1 Score: 101.679 bits (252), Expect = 1.977e-22 Identity = 56/111 (50.45%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P++ TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN K R R+ SMD Sbjct: 146 PRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIINPDGGKSGKAPRRRAVSMD 254
BLAST of Forkhead box protein vs. Ensembl Mouse
Match: Foxo3 (forkhead box O3 [Source:MGI Symbol;Acc:MGI:1890081]) HSP 1 Score: 101.679 bits (252), Expect = 1.977e-22 Identity = 56/111 (50.45%), Postives = 72/111 (64.86%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P++ TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN K R R+ SMD Sbjct: 146 PRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIINPDGGKSGKAPRRRAVSMD 254
BLAST of Forkhead box protein vs. Ensembl Mouse
Match: Foxo6 (forkhead box O6 [Source:MGI Symbol;Acc:MGI:2676586]) HSP 1 Score: 100.523 bits (249), Expect = 3.125e-22 Identity = 53/108 (49.07%), Postives = 72/108 (66.67%), Query Frame = 1 Query: 346 KSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 KSSR+N WG +Y+DLI AI S P++ TL QIY+++ + YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W +N + K R R+ SMD Sbjct: 81 KSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRV--QNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMD 186
BLAST of Forkhead box protein vs. UniProt/SwissProt
Match: sp|P98177|FOXO4_HUMAN (Forkhead box protein O4 OS=Homo sapiens OX=9606 GN=FOXO4 PE=1 SV=5) HSP 1 Score: 108.997 bits (271), Expect = 2.624e-24 Identity = 77/189 (40.74%), Postives = 97/189 (51.32%), Query Frame = 1 Query: 136 LDDCHSPEFRARSQTWG------GNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKIL-----PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNE-NMKSSLWSINTKCYK-----RERSNSMD 651 LD P+ R RS TW N S + E DL +K T S S + E P P IL P K SR+N WG ++Y++LI AI S P + TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH KF+K NE KSS W +N + K R R+ SMD Sbjct: 18 LDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEV-EPDLGEKVHT-EGRSEPILLPSRLPE---PAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMD 199
BLAST of Forkhead box protein vs. UniProt/SwissProt
Match: sp|Q9WVH3|FOXO4_MOUSE (Forkhead box protein O4 OS=Mus musculus OX=10090 GN=Foxo4 PE=1 SV=1) HSP 1 Score: 107.842 bits (268), Expect = 6.674e-24 Identity = 75/188 (39.89%), Postives = 94/188 (50.00%), Query Frame = 1 Query: 136 LDDCHSPEFRARSQTWGGN-----DNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKIL-----PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNE-NMKSSLWSINTKCYK-----RERSNSMD 651 LD P+ R RS TW + +E L QK T S S + E P P IL P K SR+N WG ++Y++LI AI S P + TL QIYE++ + YF ++ D+ SSAGWKNSIRHNLSLH KF+K NE KSS W +N K R R+ SMD Sbjct: 18 LDPDFEPQSRPRSCTWPLPRPDLATEPHEPSEVEPSLGQKVPT-EGHSEPILLPSRLPE---PAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPDGGKGGKAPRRRAASMD 199
BLAST of Forkhead box protein vs. UniProt/SwissProt
Match: sp|A3RK75|FX1AB_DANRE (Forkhead box protein O1-B OS=Danio rerio OX=7955 GN=foxo1b PE=2 SV=1) HSP 1 Score: 103.219 bits (256), Expect = 4.273e-22 Identity = 55/107 (51.40%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIYE++ K+ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N + K R R+ SMD Sbjct: 130 SSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMLNPEGGKSGKSPRRRATSMD 234
BLAST of Forkhead box protein vs. UniProt/SwissProt
Match: sp|Q66JJ0|FOXO1_XENTR (Forkhead box protein O1 OS=Xenopus tropicalis OX=8364 GN=foxo1 PE=2 SV=1) HSP 1 Score: 101.679 bits (252), Expect = 1.308e-21 Identity = 55/107 (51.40%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH KFV+ +NE KSS W +N + K R R+ SMD Sbjct: 138 SSRRNAWGNLSYADLISQAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFVRV--QNEGTGKSSWWILNPEGGKNGKSPRRRAASMD 242
BLAST of Forkhead box protein vs. UniProt/SwissProt
Match: sp|Q6EUW2|FOXO1_XENLA (Forkhead box protein O1 OS=Xenopus laevis OX=8355 GN=foxo1 PE=2 SV=1) HSP 1 Score: 101.679 bits (252), Expect = 1.358e-21 Identity = 55/107 (51.40%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH KFV+ +NE KSS W +N + K R R+ SMD Sbjct: 143 SSRRNAWGNLSYADLISQAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFVRV--QNEGTGKSSWWILNPEGGKNGKSPRRRAASMD 247
BLAST of Forkhead box protein vs. TrEMBL
Match: A0A4E0S0Z0 (Forkhead box protein O OS=Fasciola hepatica OX=6192 GN=D915_003164 PE=4 SV=1) HSP 1 Score: 162.54 bits (410), Expect = 3.295e-39 Identity = 82/139 (58.99%), Postives = 95/139 (68.35%), Query Frame = 1 Query: 274 FEESTVQENISPLKDSLPK-ILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINT----KCYKRERSNSMDC---KRSG 666 S ++ P+ P P KKSSR+NPWG ETYSDLI AI+S+P+Q ATLQQIY+FI N +YF ER D TSSAGWKNSIRHNLSLHD+F KCPK ++N KSS W INT K Y R R+ SMD KRSG Sbjct: 217 VSSSAAATSVVPINTPAPSSTTPVKKSSRRNPWGSETYSDLISIAIHSYPDQQATLQQIYDFIISNYEYFRERSDPTSSAGWKNSIRHNLSLHDRFTKCPKSSDNTKSSYWRINTEVASKPYVRRRACSMDANNLKRSG 355
BLAST of Forkhead box protein vs. TrEMBL
Match: A0A504YWL7 (Forkhead box protein O OS=Fasciola gigantica OX=46835 GN=FGIG_00041 PE=4 SV=1) HSP 1 Score: 161.77 bits (408), Expect = 5.384e-39 Identity = 82/139 (58.99%), Postives = 95/139 (68.35%), Query Frame = 1 Query: 274 FEESTVQENISPLKDSLPK-ILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINT----KCYKRERSNSMDC---KRSG 666 S ++ P+ P P KKSSR+NPWG ETYSDLI AI+S+P+Q ATLQQIY+FI N +YF ER D TSSAGWKNSIRHNLSLHD+F KCPK ++N KSS W INT K Y R R+ SMD KRSG Sbjct: 217 VSSSAAVTSVVPINTPAPSSTTPVKKSSRRNPWGSETYSDLISIAIHSYPDQQATLQQIYDFIISNYEYFRERSDPTSSAGWKNSIRHNLSLHDRFTKCPKSSDNTKSSYWRINTEVASKPYVRRRACSMDANNLKRSG 355
BLAST of Forkhead box protein vs. TrEMBL
Match: A0A430QDE2 (Forkhead box protein O3 OS=Schistosoma bovis OX=6184 GN=DC041_0007345 PE=4 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 5.713e-37 Identity = 75/117 (64.10%), Postives = 86/117 (73.50%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSIN----TKCYKRERSNSMD---CKRSG 666 P KKSSR+NPWG ETYSDLI AI S+P++ ATLQQIY+FI + +YF ER D TSSAGWKNSIRHNLSLHD+F KCPK ++N KSS W IN K Y R R+ SMD KR G Sbjct: 187 PVKKSSRRNPWGSETYSDLISVAIRSYPDKQATLQQIYDFIITHYEYFRERSDPTSSAGWKNSIRHNLSLHDRFTKCPKSSDNTKSSYWRINPDVAAKPYVRRRACSMDTTNLKRPG 303
BLAST of Forkhead box protein vs. TrEMBL
Match: A0A5J4NMI6 (Fork-head domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0004525 PE=4 SV=1) HSP 1 Score: 153.68 bits (387), Expect = 3.344e-36 Identity = 72/109 (66.06%), Postives = 85/109 (77.98%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKC----YKRERSNSMD 651 P KKSSR+NPWG ETYSDLI AI+S+P+Q ATLQQIY+FI + +YF ER D T+SAGWKNSIRHNLSLHD+F KCPK ++N KSS W INT+ Y R R+ SMD Sbjct: 205 PVKKSSRRNPWGSETYSDLITVAIHSYPDQQATLQQIYDFIITHYEYFRERSDPTTSAGWKNSIRHNLSLHDRFTKCPKSSDNTKSSYWRINTEVAARPYVRRRACSMD 313
BLAST of Forkhead box protein vs. TrEMBL
Match: A0A1S8XB37 (Fork head domain protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_00162 PE=4 SV=1) HSP 1 Score: 152.14 bits (383), Expect = 8.072e-36 Identity = 72/109 (66.06%), Postives = 84/109 (77.06%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINT----KCYKRERSNSMD 651 P KKSSR+NPWG ETYSDLI AI+S+P+Q ATLQQIY+FI + +YF ER D +SAGWKNSIRHNLSLHD+F KCPK ++N KSS W INT K Y R R+ SMD Sbjct: 198 PVKKSSRRNPWGPETYSDLISVAIHSYPDQQATLQQIYDFIITHYEYFRERSDPATSAGWKNSIRHNLSLHDRFTKCPKSSDNTKSSYWRINTEVASKPYVRRRACSMD 306
BLAST of Forkhead box protein vs. Ensembl Cavefish
Match: foxo4 (forkhead box protein O4-like [Source:NCBI gene;Acc:103022611]) HSP 1 Score: 105.916 bits (263), Expect = 6.517e-24 Identity = 56/111 (50.45%), Postives = 74/111 (66.67%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG ++Y+DLI AI + P + TL QIYE++ K YF ++ D+ SSAGWKNSIRHNLSLH+KF++ NE+ KSS W +N + K R R+ SMD Sbjct: 84 PRKGSSRRNAWGNQSYADLISQAIENSPEKRLTLAQIYEWMVKTVPYFKDKGDSNSSAGWKNSIRHNLSLHNKFLRV--HNESTGKSSWWMLNPEGGKPGKAPRRRAASMD 192
BLAST of Forkhead box protein vs. Ensembl Cavefish
Match: foxo3b (forkhead box O3 [Source:NCBI gene;Acc:103022904]) HSP 1 Score: 103.605 bits (257), Expect = 3.126e-23 Identity = 55/111 (49.55%), Postives = 74/111 (66.67%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P++ TL QIY+++ ++ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W IN + + R R+ SMD Sbjct: 117 PRKTSSRRNAWGNLSYADLITKAIESTPDKRLTLSQIYDWMVRSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMINPEGGRGGKAPRRRAVSMD 225
BLAST of Forkhead box protein vs. Ensembl Cavefish
Match: foxo1b (forkhead box protein O1-B-like [Source:NCBI gene;Acc:103046520]) HSP 1 Score: 102.449 bits (254), Expect = 7.024e-23 Identity = 57/115 (49.57%), Postives = 74/115 (64.35%), Query Frame = 1 Query: 334 LPAKK---SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 LP ++ SSR+N WG +Y+DLI AI S P + TL QIYE++ K+ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N K R R+ SMD Sbjct: 112 LPGQRKSSSSRRNAWGNMSYADLITRAIESSPEKRLTLSQIYEWMVKSVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMLNPDGGKSGKSPRRRAASMD 224
BLAST of Forkhead box protein vs. Ensembl Cavefish
Match: foxo1a (forkhead box O1 [Source:NCBI gene;Acc:103032706]) HSP 1 Score: 102.064 bits (253), Expect = 1.273e-22 Identity = 54/107 (50.47%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N + K R R+ SMD Sbjct: 126 SSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMLNPEGGKSGKSPRRRAASMD 230
BLAST of Forkhead box protein vs. Ensembl Cavefish
Match: foxo1a (forkhead box O1 [Source:NCBI gene;Acc:103032706]) HSP 1 Score: 102.064 bits (253), Expect = 1.273e-22 Identity = 54/107 (50.47%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N + K R R+ SMD Sbjct: 126 SSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRV--QNEGTGKSSWWMLNPEGGKSGKSPRRRAASMD 230
BLAST of Forkhead box protein vs. Ensembl Sea Lamprey
Match: foxk1 (forkhead box K1 [Source:ZFIN;Acc:ZDB-GENE-030131-6402]) HSP 1 Score: 73.559 bits (179), Expect = 3.272e-14 Identity = 48/147 (32.65%), Postives = 73/147 (49.66%), Query Frame = 1 Query: 274 FEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINT--------KCYKRERSNSMDCKRSGVDLIARR 687 F +S ++ PL +S K P+ +Y+ LI AI S ++ TL IY +ISK+ Y+ S GW+NSIRHNLSL+ FVK P+ E+ K S W I+ + Y++ R+ + C R+ L++ R Sbjct: 183 FAQSAAEKEAEPLDES------------KPPY---SYAQLIVQAITSAASKQLTLSGIYAYISKHYPYYR-----ASDKGWQNSIRHNLSLNRYFVKVPRSQEDPGKGSFWRIDPASEGKLAEQAYRKRRARGVPCFRAPFGLLSSR 309
BLAST of Forkhead box protein vs. Ensembl Sea Lamprey
Match: foxk1 (forkhead box K1 [Source:ZFIN;Acc:ZDB-GENE-030131-6402]) HSP 1 Score: 73.559 bits (179), Expect = 3.283e-14 Identity = 48/147 (32.65%), Postives = 73/147 (49.66%), Query Frame = 1 Query: 274 FEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINT--------KCYKRERSNSMDCKRSGVDLIARR 687 F +S ++ PL +S K P+ +Y+ LI AI S ++ TL IY +ISK+ Y+ S GW+NSIRHNLSL+ FVK P+ E+ K S W I+ + Y++ R+ + C R+ L++ R Sbjct: 183 FAQSAAEKEAEPLDES------------KPPY---SYAQLIVQAITSAASKQLTLSGIYAYISKHYPYYR-----ASDKGWQNSIRHNLSLNRYFVKVPRSQEDPGKGSFWRIDPASEGKLAEQAYRKRRARGVPCFRAPFGLLSSR 309
BLAST of Forkhead box protein vs. Ensembl Sea Lamprey
Match: foxi3b (forkhead box I3b [Source:ZFIN;Acc:ZDB-GENE-031126-4]) HSP 1 Score: 68.9366 bits (167), Expect = 5.594e-13 Identity = 43/128 (33.59%), Postives = 67/128 (52.34%), Query Frame = 1 Query: 361 NPW----GQE----------TYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKC--------YKRERSNSMDCKRSGVDL 675 NPW GQ+ +YS LI AI P + TL QIY+++++N ++ + S AGW+NSIRHNLSL+D F K P+ +++ K + W ++ C ++R+R D +G L Sbjct: 103 NPWLSYQGQQDFFRLVRPPYSYSALIAMAIQHTPEKRLTLSQIYQYVAENYPFYKK-----SKAGWQNSIRHNLSLNDCFKKVPRDDDDPGKGNYWILDPNCEKMFDNGNFRRKRKRKSDMSPNGTAL 225
BLAST of Forkhead box protein vs. Ensembl Sea Lamprey
Match: foxj3 (forkhead box J3 [Source:ZFIN;Acc:ZDB-GENE-101005-1]) HSP 1 Score: 68.9366 bits (167), Expect = 9.125e-13 Identity = 40/98 (40.82%), Postives = 58/98 (59.18%), Query Frame = 1 Query: 379 TYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPK-KNENMKSSLWSIN---------TKCYKRERSN 642 +Y++LI AINS + TL +IY++I N Y+ E + GWKNSIRHNLSL+ F+K P+ +++ K S W+I+ T+ KR RSN Sbjct: 72 SYANLITFAINSSARKRMTLSEIYQWICDNFPYYKE-----AGIGWKNSIRHNLSLNKCFIKVPRSRDDPGKGSYWAIDQNPSDENSSTRPKKRPRSN 164
BLAST of Forkhead box protein vs. Ensembl Sea Lamprey
Match: foxk1 (forkhead box K1 [Source:ZFIN;Acc:ZDB-GENE-030131-6402]) HSP 1 Score: 65.4698 bits (158), Expect = 2.417e-12 Identity = 38/112 (33.93%), Postives = 59/112 (52.68%), Query Frame = 1 Query: 379 TYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPK-KNENMKSSLWSINT--------KCYKRERSNSMDCKRSGVDLIARR 687 +Y+ LI AI S ++ TL IY I+K+ Y+ T+ GW+NSIRHNLSL+ FVK P+ + E K S W I+ + +++ R + C R+ ++ R Sbjct: 131 SYAQLIVQAITSALDKQLTLSGIYAHITKHYPYYR-----TADKGWQNSIRHNLSLNRYFVKVPRSQEEPGKGSFWRIDPPSEGKLAEQAFRKRRQRGVPCFRTPFGPLSSR 237
BLAST of Forkhead box protein vs. Ensembl Yeast
Match: FKH2 (Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia [Source:SGD;Acc:S000005012]) HSP 1 Score: 61.2326 bits (147), Expect = 2.113e-10 Identity = 38/99 (38.38%), Postives = 57/99 (57.58%), Query Frame = 1 Query: 379 TYSDLIEAAINSHPNQMATLQQIYEFISKNNKY--FAERVDATSSAGWKNSIRHNLSLHDKFVKCPKK-NENMKSSLWSINTKCYKRERSNSMDCKRSG 666 +Y+ +I AI S P + +L IY++IS N Y FA+ +GW+NSIRHNLSL+ F K P++ NE K W I ++ Y++E N + + G Sbjct: 344 SYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAK-------SGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRI-SESYQQEFLNKWNTGKVG 434
BLAST of Forkhead box protein vs. Ensembl Yeast
Match: FKH1 (Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching [Source:SGD;Acc:S000001393]) HSP 1 Score: 53.1434 bits (126), Expect = 5.294e-8 Identity = 30/79 (37.97%), Postives = 43/79 (54.43%), Query Frame = 1 Query: 376 ETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKK-NENMKSSLWSI 609 ++Y+ +I AI S P +L IY+FIS N ++ S W+NS+RHNLSL+ F K PK+ + K W I Sbjct: 306 QSYASMITQAILSTPEGSISLADIYKFISDNYAFYR-----FSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKI 379
BLAST of Forkhead box protein vs. Ensembl Yeast
Match: HCM1 (Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661]) HSP 1 Score: 50.0618 bits (118), Expect = 5.720e-7 Identity = 35/98 (35.71%), Postives = 53/98 (54.08%), Query Frame = 1 Query: 352 SRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSI----NTKCYKRE 633 ++K P+ +Y+ LI AI TL QIY +I + Y+ ++ A W+NSIRHNLSL+D F+K +K+ + K W + TK +K E Sbjct: 107 AKKPPY---SYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQK-----DASWQNSIRHNLSLNDAFIKT-EKSCDGKGHFWEVRPGAETKFFKGE 195
BLAST of Forkhead box protein vs. Ensembl Nematostella
Match: EDO31077 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYZ1]) HSP 1 Score: 83.1889 bits (204), Expect = 1.179e-19 Identity = 41/87 (47.13%), Postives = 55/87 (63.22%), Query Frame = 1 Query: 361 NPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKC 621 NPWG E+YS++I AI S P+Q ATL IYE+I N YFA++ D S+ GWKN+IRH LS+ +F + + SSLW+ K Sbjct: 2 NPWGSESYSEMISKAIMSCPSQEATLHTIYEWIVNNVSYFADKADYPSTHGWKNAIRHTLSIRKRFTRIIDISSP-HSSLWTFTHKA 87
BLAST of Forkhead box protein vs. Ensembl Nematostella
Match: EDO31996 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWD7]) HSP 1 Score: 76.6406 bits (187), Expect = 1.811e-17 Identity = 38/87 (43.68%), Postives = 50/87 (57.47%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSI 609 +KNPWG +YSDLI AI+ Q TL QIY++ N YF + S+ GWKN+IRH LSL +FV+ P N S W++ Sbjct: 1 GEKKNPWGNASYSDLIARAIDQSKFQKLTLPQIYDWFVINVPYFKAKEHLPSTKGWKNAIRHTLSLRQRFVRLPDPG-NPYRSWWTV 86
BLAST of Forkhead box protein vs. Ensembl Nematostella
Match: EDO47844 (Forkhead domain protein O2-like protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKZ3]) HSP 1 Score: 75.8702 bits (185), Expect = 3.221e-17 Identity = 39/85 (45.88%), Postives = 49/85 (57.65%), Query Frame = 1 Query: 355 RKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSI 609 +K PWG +YSDLI AI Q TL QIYE+ +N YF +R S+ GWKN+IRH LSL +FV+ N S WS+ Sbjct: 1 KKKPWGNASYSDLIARAITQSTKQKLTLPQIYEWFVENVSYFRDREHLPSTKGWKNAIRHTLSLRQRFVRTVDPT-NPYRSWWSL 84
BLAST of Forkhead box protein vs. Ensembl Nematostella
Match: EDO27489 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T943]) HSP 1 Score: 65.0846 bits (157), Expect = 1.054e-13 Identity = 30/57 (52.63%), Postives = 39/57 (68.42%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWK 519 S +NPWG E+YS++I AI S P+Q ATL IYE+I N YFA++ D S+ GWK Sbjct: 1 SKTQNPWGSESYSEMISKAIMSCPSQEATLHTIYEWIVNNVSYFADKADYPSTHGWK 57
BLAST of Forkhead box protein vs. Ensembl Nematostella
Match: EDO36951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SH30]) HSP 1 Score: 66.2402 bits (160), Expect = 1.122e-13 Identity = 36/82 (43.90%), Postives = 49/82 (59.76%), Query Frame = 1 Query: 379 TYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPK-KNENMKSSLWSINTKC 621 +Y+ LI AI S ++ TL IY I+KN Y+ T+ GW+NSIRHNLSL+ FVK P+ ++E K S W I+ C Sbjct: 8 SYAQLIVQAILSATDKQLTLSGIYAHITKNYPYYR-----TADKGWQNSIRHNLSLNRYFVKVPRAQDEPGKGSFWRIDPSC 84
BLAST of Forkhead box protein vs. Ensembl Medaka
Match: foxo4 (forkhead box protein O6 [Source:NCBI gene;Acc:110015734]) HSP 1 Score: 103.605 bits (257), Expect = 2.966e-23 Identity = 55/109 (50.46%), Postives = 73/109 (66.97%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 K SSR+N WG ++Y+DLI AI + P + TL QIYE++ K YF ++ D+ SSAGWKNSIRHNLSLH+KF++ NE+ KSS W +N + K R R+ SMD Sbjct: 89 KGSSRRNAWGNQSYADLISQAIENSPEKRLTLAQIYEWMVKTVPYFRDKGDSNSSAGWKNSIRHNLSLHNKFLRV--HNESTGKSSWWMLNPEGGKTGKAPRRRAASMD 195
BLAST of Forkhead box protein vs. Ensembl Medaka
Match: foxo3 (forkhead box O3 [Source:NCBI gene;Acc:100301621]) HSP 1 Score: 103.605 bits (257), Expect = 3.201e-23 Identity = 55/111 (49.55%), Postives = 73/111 (65.77%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P + TL QIY+++ ++ YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN + K R R+ SMD Sbjct: 125 PRKTSSRRNAWGNLSYADLITQAIESSPEKRLTLSQIYDWMVRSIPYFKDKGDSNSSAGWKNSIRHNLSLHSRFIRV--QNEGTGKSSWWMINPEGGKGGKAPRRRAVSMD 233
BLAST of Forkhead box protein vs. Ensembl Medaka
Match: foxo3 (forkhead box O3 [Source:NCBI gene;Acc:100301621]) HSP 1 Score: 103.605 bits (257), Expect = 3.201e-23 Identity = 55/111 (49.55%), Postives = 73/111 (65.77%), Query Frame = 1 Query: 337 PAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 P K SSR+N WG +Y+DLI AI S P + TL QIY+++ ++ YF ++ D+ SSAGWKNSIRHNLSLH +F++ +NE KSS W IN + K R R+ SMD Sbjct: 125 PRKTSSRRNAWGNLSYADLITQAIESSPEKRLTLSQIYDWMVRSIPYFKDKGDSNSSAGWKNSIRHNLSLHSRFIRV--QNEGTGKSSWWMINPEGGKGGKAPRRRAVSMD 233
BLAST of Forkhead box protein vs. Ensembl Medaka
Match: ENSORLT00000040588.1 (pep primary_assembly:ASM223467v1:22:547169:550450:1 gene:ENSORLG00000024046.1 transcript:ENSORLT00000040588.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 102.449 bits (254), Expect = 6.511e-23 Identity = 53/109 (48.62%), Postives = 73/109 (66.97%), Query Frame = 1 Query: 343 KKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 K S+R+N WG +Y+DLI AI+ P++ TL QIY+++ ++ YF ++ D+ SSAGWKNSIRHNLSLH +FVK +NE KSS W +N + K R R+ SMD Sbjct: 115 KSSARRNAWGNYSYADLITQAIDGSPDKRLTLAQIYDWMVRSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVKV--QNEGTGKSSWWVVNPEGGKGGKAPRRRAVSMD 221
BLAST of Forkhead box protein vs. Ensembl Medaka
Match: ENSORLT00000009665.2 (forkhead box protein O1-A [Source:NCBI gene;Acc:101164740]) HSP 1 Score: 99.7525 bits (247), Expect = 5.809e-22 Identity = 54/107 (50.47%), Postives = 71/107 (66.36%), Query Frame = 1 Query: 349 SSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSINTKCYK-----RERSNSMD 651 SSR+N WG +Y+DLI AI S P + TL QIY+++ K+ YF ++ D+ SSAGWKNSIRHNLSLH +FV+ +NE KSS W +N + K R R+ SMD Sbjct: 121 SSRRNAWGNMSYADLITKAIESSPEKRLTLSQIYDWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFVRL--QNEGTGKSSWWMLNPEGGKNGKSPRRRAVSMD 225
BLAST of Forkhead box protein vs. Planmine SMEST
Match: SMESG000037781.1 (SMESG000037781.1) HSP 1 Score: 652.514 bits (1682), Expect = 0.000e+0 Identity = 333/333 (100.00%), Postives = 333/333 (100.00%), Query Frame = 1 Query: 124 MNNMLDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQRRHXXXXXXXXXXXXXXXXXDKYTAATDDNSIHKLSPNNQSSFTYDSAESAMETISDFIYKDNKLKYRSPQTIHESNKEMQLDSSYNKYDCHLHQTLHEDLQRLDVNSMEHYHYKKDQNFNYNKSQCLDFHRAALEYSR 1122 MNNMLDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQRRHISSNSNIVSNSKISPNSDKYTAATDDNSIHKLSPNNQSSFTYDSAESAMETISDFIYKDNKLKYRSPQTIHESNKEMQLDSSYNKYDCHLHQTLHEDLQRLDVNSMEHYHYKKDQNFNYNKSQCLDFHRAALEYSR Sbjct: 1 MNNMLDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQRRHISSNSNIVSNSKISPNSDKYTAATDDNSIHKLSPNNQSSFTYDSAESAMETISDFIYKDNKLKYRSPQTIHESNKEMQLDSSYNKYDCHLHQTLHEDLQRLDVNSMEHYHYKKDQNFNYNKSQCLDFHRAALEYSR 333
BLAST of Forkhead box protein vs. Planmine SMEST
Match: SMESG000037781.1 (SMESG000037781.1) HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0 Identity = 330/330 (100.00%), Postives = 330/330 (100.00%), Query Frame = 1 Query: 133 MLDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQRRHXXXXXXXXXXXXXXXXXDKYTAATDDNSIHKLSPNNQSSFTYDSAESAMETISDFIYKDNKLKYRSPQTIHESNKEMQLDSSYNKYDCHLHQTLHEDLQRLDVNSMEHYHYKKDQNFNYNKSQCLDFHRAALEYSR 1122 MLDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQRRHISSNSNIVSNSKISPNSDKYTAATDDNSIHKLSPNNQSSFTYDSAESAMETISDFIYKDNKLKYRSPQTIHESNKEMQLDSSYNKYDCHLHQTLHEDLQRLDVNSMEHYHYKKDQNFNYNKSQCLDFHRAALEYSR Sbjct: 1 MLDDCHSPEFRARSQTWGGNDNSYRSRIIEADLSQKYTTFASDSYTSFEESTVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENMKSSLWSINTKCYKRERSNSMDCKRSGVDLIARRKLLKEQRRHISSNSNIVSNSKISPNSDKYTAATDDNSIHKLSPNNQSSFTYDSAESAMETISDFIYKDNKLKYRSPQTIHESNKEMQLDSSYNKYDCHLHQTLHEDLQRLDVNSMEHYHYKKDQNFNYNKSQCLDFHRAALEYSR 330
BLAST of Forkhead box protein vs. Planmine SMEST
Match: SMESG000075929.1 (SMESG000075929.1) HSP 1 Score: 67.3958 bits (163), Expect = 1.029e-12 Identity = 44/110 (40.00%), Postives = 60/110 (54.55%), Query Frame = 1 Query: 286 TVQENISPLKDSLPKILPAKKSSRKNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSIN 612 TV +NI KI K+ K P+ +Y LI AI + P Q TL +IYE++S++ K+F GWKNSIRHNLSL+D F+K PK + K W++N Sbjct: 18 TVDQNI--------KIALTKEIYLKPPF---SYISLIAMAIQASPYQQCTLNEIYEYLSEHFKFFRGEYQ-----GWKNSIRHNLSLNDCFIKIPKGFGRIGKGHYWTMN 111
BLAST of Forkhead box protein vs. Planmine SMEST
Match: SMESG000075929.1 (SMESG000075929.1) HSP 1 Score: 65.855 bits (159), Expect = 3.598e-12 Identity = 35/79 (44.30%), Postives = 48/79 (60.76%), Query Frame = 1 Query: 379 TYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNENM-KSSLWSIN 612 +Y LI AI + P Q TL +IYE++S++ K+F GWKNSIRHNLSL+D F+K PK + K W++N Sbjct: 40 SYISLIAMAIQASPYQQCTLNEIYEYLSEHFKFFRGEYQ-----GWKNSIRHNLSLNDCFIKIPKGFGRIGKGHYWTMN 113
BLAST of Forkhead box protein vs. Planmine SMEST
Match: SMESG000015673.1 (SMESG000015673.1) HSP 1 Score: 65.0846 bits (157), Expect = 4.598e-11 Identity = 37/104 (35.58%), Postives = 61/104 (58.65%), Query Frame = 1 Query: 325 PKILPAKKSSR---KNPWGQETYSDLIEAAINSHPNQMATLQQIYEFISKNNKYFAERVDATSSAGWKNSIRHNLSLHDKFVKCPKKNEN-MKSSLWSINTKCY 624 P + ++ SR K P+ +Y LI A+++HP + TL IY+FI + Y+ E + GW+NSIRHNLSL++ F+K P+ ++ K S W+++ + Y Sbjct: 59 PNMSSSRNPSRDLVKPPY---SYIALITMAVHAHPEKKVTLSGIYQFIMEKFPYYRE-----NKQGWQNSIRHNLSLNECFIKIPRDDKKPGKGSYWALHPQAY 154 The following BLAST results are available for this feature:
BLAST of Forkhead box protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Forkhead box protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Forkhead box protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Forkhead box protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Forkhead box protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Forkhead box protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012265 ID=SMED30012265|Name=Forkhead box protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1407bpback to top protein sequence of SMED30012265-orf-1 >SMED30012265-orf-1 ID=SMED30012265-orf-1|Name=SMED30012265-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=364bp MFSNYPLESLLITNSYSLAMNNMLDDCHSPEFRARSQTWGGNDNSYRSRIback to top Aliases
The feature 'Forkhead box protein' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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