Elongator complex protein 3

Overview


Name	Elongator complex protein 3
Smed ID	SMED30012263
Length (bp)	1809

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Elongator complex protein 3 (SMED30012263) t-SNE clustered cells

Violin plots show distribution of expression levels for Elongator complex protein 3 (SMED30012263) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Elongator complex protein 3 (SMED30012263) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Elongator complex protein 3 (SMED30012263) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012263

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30012263	SMESG000011834.1	SmedASXL_009384	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30012263	SMESG000011834.1	SmedASXL_009384	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

Note: Hover over icons to view figure legend

Homology

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BLAST of Elongator complex protein 3 vs. Ensembl Human
Match: ELP3 (elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696])

HSP 1 Score: 902.894 bits (2332), Expect = 0.000e+0
Identity = 434/557 (77.92%), Postives = 496/557 (89.05%), Query Frame = 3

Query:   51 MGKAKKVDKS-QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M + +K D S  + MM TI ++I++LI+A+ + + +DLNK+KTK ++K GL  QPRLVDII  VP +Y+K+L+P+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S N+ EAVKYSERS TKC+GITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KD+GFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ L++L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG++CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:    1 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKML 546

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BLAST of Elongator complex protein 3 vs. Ensembl Human
Match: ELP3 (elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696])

HSP 1 Score: 902.123 bits (2330), Expect = 0.000e+0
Identity = 430/543 (79.19%), Postives = 489/543 (90.06%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM TI ++I++LI+A+ + + +DLNK+KTK ++K GL  QPRLVDII  VP +Y+K+L+P+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S N+ EAVKYSERS TKC+GITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KD+GFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ L++L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG++CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:    1 MMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKML 532

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BLAST of Elongator complex protein 3 vs. Ensembl Human
Match: ELP3 (elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696])

HSP 1 Score: 833.558 bits (2152), Expect = 0.000e+0
Identity = 399/485 (82.27%), Postives = 443/485 (91.34%), Query Frame = 3

Query:  264 VPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            +P+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S N+ EAVKYSERS TKC+GITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KD+GFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ L++L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG++CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:    1 MPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKML 474

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Human
Match: ELP3 (elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696])

HSP 1 Score: 801.586 bits (2069), Expect = 0.000e+0
Identity = 384/465 (82.58%), Postives = 424/465 (91.18%), Query Frame = 3

Query:  324 MCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S N+ EAVKYSERS TKC+GITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KD+GFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ L++L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG++CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:    1 MCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKML 454

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Human
Match: ELP3 (elongator acetyltransferase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:20696])

HSP 1 Score: 716.072 bits (1847), Expect = 0.000e+0
Identity = 346/426 (81.22%), Postives = 386/426 (90.61%), Query Frame = 3

Query:  441 PTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            PTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S N+ EAVKYSERS TKC+GITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KD+GFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ L++L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG++CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:   13 PTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKML 427

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BLAST of Elongator complex protein 3 vs. Ensembl Celegans
Match: elpc-3 (Probable elongator complex protein 3 [Source:UniProtKB/Swiss-Prot;Acc:Q23651])

HSP 1 Score: 840.491 bits (2170), Expect = 0.000e+0
Identity = 399/543 (73.48%), Postives = 472/543 (86.92%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            + +TI+EI++ LI+A+++ + V+LN+LK  ++ KNGL +QP+LVDII GVP +YK  L+P+LKAKPVR+ASGI VVAVM KPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY+P+LQTR RL QL QLGHSVDKVEFIVMGGTFM+L  +YRD+FIRNLHDALSGH S +VEEAV YSERS  KC+GITIETRPDYCL +HL+DML YGCTRLEIGVQS YEDVARDTNRGHTVK+VCE+FH +KD G+KVV HMMPDLPNVG +RD+ QF E FE+PAFR DGLK+YPTLVIRGTGLYELWKT +Y SYPP+VL+DLIA IL+LVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+ A+A+M ELG+KCRDVRTREVG+QEI++K+RP  +EL+RRDY ANGGWETF+SYEDP QDIL+GL RLR+ S +  RPEL    K ++       S++RELHVYG+ V +  +DP KFQHQG+G LL+EE+ERIAR+EHGS KIA+ISGVGTR YYRK+GYEL+GPYM KML
Sbjct:   11 LAQTINEIVKLLIEAHNQKKDVNLNRLKCIVAQKNGLSFQPKLVDIIAGVPSDYKDSLLPKLKAKPVRTASGIAVVAVMSKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPYLQTRGRLNQLMQLGHSVDKVEFIVMGGTFMSLPEDYRDFFIRNLHDALSGHTSASVEEAVAYSERSKMKCIGITIETRPDYCLPRHLNDMLLYGCTRLEIGVQSTYEDVARDTNRGHTVKSVCETFHMAKDTGYKVVIHMMPDLPNVGLERDKEQFLELFESPAFRPDGLKLYPTLVIRGTGLYELWKTGRYQSYPPSVLVDLIATILSLVPPWTRVYRVQRDIPMPLVSSGVEHGNLREHAMAKMKELGLKCRDVRTREVGIQEIHNKVRPEDVELIRRDYTANGGWETFISYEDPKQDILIGLLRLRKISDKAHRPEL----KGNV-------SVVRELHVYGSVVSVADRDPKKFQHQGYGSLLMEEAERIAREEHGSDKIAVISGVGTREYYRKLGYELDGPYMSKML 542

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BLAST of Elongator complex protein 3 vs. Ensembl Fly
Match: Elp3 (gene:FBgn0031604 transcript:FBtr0077439)

HSP 1 Score: 888.641 bits (2295), Expect = 0.000e+0
Identity = 421/549 (76.68%), Postives = 487/549 (88.71%), Query Frame = 3

Query:   81 QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML*RN 1727
            Q+  +  I EII+EL+KA+   + V+LN++K+ ++SK GL   PRLVDII  VPQ+ KKIL+P+L+AKP+R+ASGI VVAVMCKPHRCPHI+MTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIR+RYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFM L  EYRDYFIRNLHDALSGH S NV EAV+YSE+S TKC+GITIETRPDYCLK+H+SDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESF   KDAG+K+V HMMPDLPNV ++RD  QF E+FENPAFR+DGLKIYPTLVIRGTGLYELWKT +Y SYPP++L+DL+A+ILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG  CRDVRTREVG+QEI++K+RPY+IEL+RRDYVANGGWETFLSYEDP+QDILVGL RLR+CS + FRPEL         G+   CSI+RELHVYG+ VP+NA+DPTKFQHQGFG LL+EE+ERIAR+EHGS K+A+ISGVGTRNYYRKMGY+L+GPYM K +  N
Sbjct:   14 QERQVLVIGEIIQELLKAHEAKKDVNLNRMKSLVASKYGLDSSPRLVDIIAAVPQDAKKILLPKLRAKPIRTASGIAVVAVMCKPHRCPHINMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRSRYDPFLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMCLPEEYRDYFIRNLHDALSGHSSANVAEAVRYSEKSRTKCIGITIETRPDYCLKRHISDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFQLGKDAGYKIVTHMMPDLPNVDFERDIEQFIEYFENPAFRSDGLKIYPTLVIRGTGLYELWKTGRYKSYPPSMLVDLVAKILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTTCRDVRTREVGIQEIHNKVRPYEIELIRRDYVANGGWETFLSYEDPEQDILVGLLRLRKCSPDTFRPEL--------KGE---CSIVRELHVYGSVVPVNARDPTKFQHQGFGMLLMEEAERIAREEHGSTKLAVISGVGTRNYYRKMGYQLDGPYMSKSIEEN 551

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BLAST of Elongator complex protein 3 vs. Ensembl Zebrafish
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:541509])

HSP 1 Score: 926.776 bits (2394), Expect = 0.000e+0
Identity = 430/543 (79.19%), Postives = 488/543 (89.87%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM TI+++I++L++A+ E + ++LNK+KTK S+K GL  QPRLVDII  VP  Y++ LVP+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S NV EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MMMTIADVIKQLVEAHEEGKDINLNKVKTKTSAKYGLSAQPRLVDIIAAVPPHYRRALVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNVTEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLGYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGMERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSALVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KGGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSSKLAVISGVGTRNYYRKMGYELEGPYMVKNL 532

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BLAST of Elongator complex protein 3 vs. Ensembl Zebrafish
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:541509])

HSP 1 Score: 826.624 bits (2134), Expect = 0.000e+0
Identity = 384/465 (82.58%), Postives = 424/465 (91.18%), Query Frame = 3

Query:  324 MCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S NV EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNVTEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLGYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGMERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSALVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KGGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSSKLAVISGVGTRNYYRKMGYELEGPYMVKNL 454

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BLAST of Elongator complex protein 3 vs. Ensembl Xenopus
Match: gucd1 (guanylyl cyclase domain containing 1 [Source:Xenbase;Acc:XB-GENE-941300])

HSP 1 Score: 908.672 bits (2347), Expect = 0.000e+0
Identity = 429/543 (79.01%), Postives = 490/543 (90.24%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   26 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALSEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMAKDAGFKVVSHMMPDLPNVGLERDTEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEQSFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIAREEHGSWKIAVISGVGTRNYYRKLGYELEGPYMVKKL 557

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BLAST of Elongator complex protein 3 vs. Ensembl Xenopus
Match: gucd1 (guanylyl cyclase domain containing 1 [Source:Xenbase;Acc:XB-GENE-941300])

HSP 1 Score: 907.516 bits (2344), Expect = 0.000e+0
Identity = 429/543 (79.01%), Postives = 490/543 (90.24%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   10 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALSEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMAKDAGFKVVSHMMPDLPNVGLERDTEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEQSFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIAREEHGSWKIAVISGVGTRNYYRKLGYELEGPYMVKKL 541

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Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   17 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALSEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMAKDAGFKVVSHMMPDLPNVGLERDTEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEQSFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIAREEHGSWKIAVISGVGTRNYYRKLGYELEGPYMVKKL 548

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Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   88 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALSEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMAKDAGFKVVSHMMPDLPNVGLERDTEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEQSFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIAREEHGSWKIAVISGVGTRNYYRKLGYELEGPYMVKKL 619

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BLAST of Elongator complex protein 3 vs. Ensembl Xenopus
Match: gucd1 (guanylyl cyclase domain containing 1 [Source:Xenbase;Acc:XB-GENE-941300])

HSP 1 Score: 906.746 bits (2342), Expect = 0.000e+0
Identity = 429/543 (79.01%), Postives = 490/543 (90.24%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   18 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALSEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMAKDAGFKVVSHMMPDLPNVGLERDTEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEQSFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIAREEHGSWKIAVISGVGTRNYYRKLGYELEGPYMVKKL 549

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BLAST of Elongator complex protein 3 vs. Ensembl Mouse
Match: Elp3 (elongator acetyltransferase complex subunit 3 [Source:MGI Symbol;Acc:MGI:1921445])

HSP 1 Score: 895.96 bits (2314), Expect = 0.000e+0
Identity = 426/543 (78.45%), Postives = 485/543 (89.32%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM TI ++I++L++A+ + + VDLNK+KTK ++K GL  QPRLVDII  VP  Y+KIL+P+LKAKPVR+ASGI VVAVMCKPHRCPHIS TGNIC+YCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIR+LHDALSGH S N+ EA+KYSERS TKCVGITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKA CESFH +KD+GFKVV HMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ LI+L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LA ARM +LG++CRDVRTREVG+QEI+H++RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS K+A+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:   34 MMLTIGDVIKQLVEAHEQGKDVDLNKMKTKTAAKYGLASQPRLVDIIAAVPPHYRKILIPKLKAKPVRTASGIAVVAVMCKPHRCPHISFTGNICIYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRSLHDALSGHTSNNIHEAIKYSERSFTKCVGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAACESFHLAKDSGFKVVTHMMPDLPNVGLERDIEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYRSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAFARMKDLGIQCRDVRTREVGIQEIHHRVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKMAVISGVGTRNYYRKIGYRLQGPYMVKML 565

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Mouse
Match: Elp3 (elongator acetyltransferase complex subunit 3 [Source:MGI Symbol;Acc:MGI:1921445])

HSP 1 Score: 895.96 bits (2314), Expect = 0.000e+0
Identity = 430/557 (77.20%), Postives = 492/557 (88.33%), Query Frame = 3

Query:   51 MGKAKKVDKS-QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M + +K D S  + MM TI ++I++L++A+ + + VDLNK+KTK ++K GL  QPRLVDII  VP  Y+KIL+P+LKAKPVR+ASGI VVAVMCKPHRCPHIS TGNIC+YCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIR+LHDALSGH S N+ EA+KYSERS TKCVGITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKA CESFH +KD+GFKVV HMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ LI+L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LA ARM +LG++CRDVRTREVG+QEI+H++RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS K+A+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:    1 MRQKRKGDLSPAELMMLTIGDVIKQLVEAHEQGKDVDLNKMKTKTAAKYGLASQPRLVDIIAAVPPHYRKILIPKLKAKPVRTASGIAVVAVMCKPHRCPHISFTGNICIYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRSLHDALSGHTSNNIHEAIKYSERSFTKCVGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAACESFHLAKDSGFKVVTHMMPDLPNVGLERDIEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYRSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAFARMKDLGIQCRDVRTREVGIQEIHHRVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKMAVISGVGTRNYYRKIGYRLQGPYMVKML 546

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BLAST of Elongator complex protein 3 vs. Ensembl Mouse
Match: Elp3 (elongator acetyltransferase complex subunit 3 [Source:MGI Symbol;Acc:MGI:1921445])

HSP 1 Score: 850.507 bits (2196), Expect = 0.000e+0
Identity = 410/534 (76.78%), Postives = 470/534 (88.01%), Query Frame = 3

Query:   51 MGKAKKVDKS-QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISG 1649
            M + +K D S  + MM TI ++I++L++A+ + + VDLNK+KTK ++K GL  QPRLVDII  VP  Y+KIL+P+LKAKPVR+ASGI VVAVMCKPHRCPHIS TGNIC+YCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIR+LHDALSGH S N+ EA+KYSERS TKCVGITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKA CESFH +KD+GFKVV HMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ LI+L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LA ARM +LG++CRDVRTREVG+QEI+H++RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS K+A+ISG
Sbjct:    1 MRQKRKGDLSPAELMMLTIGDVIKQLVEAHEQGKDVDLNKMKTKTAAKYGLASQPRLVDIIAAVPPHYRKILIPKLKAKPVRTASGIAVVAVMCKPHRCPHISFTGNICIYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRSLHDALSGHTSNNIHEAIKYSERSFTKCVGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAACESFHLAKDSGFKVVTHMMPDLPNVGLERDIEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYRSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAFARMKDLGIQCRDVRTREVGIQEIHHRVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKMAVISG 523

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BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
Match: sp|Q5ZHS1|ELP3_CHICK (Elongator complex protein 3 OS=Gallus gallus OX=9031 GN=ELP3 PE=2 SV=1)

HSP 1 Score: 932.554 bits (2409), Expect = 0.000e+0
Identity = 437/556 (78.60%), Postives = 495/556 (89.03%), Query Frame = 3

Query:   51 MGKAKKVDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MG+ +K     + MM TI++II++LI+A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +++K LVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRDYFIRNLHDALSGH S NV EAVKYSERS TKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVVAHMMPDLPN+G +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SYPP+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQIEL+RRDYVANGGWETFLSYEDP+QDILVGL RLR+CS E FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG LL+EE+ERIA++EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:    1 MGQKRKDLSHAELMMMTIADIIKQLIEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQHRKALVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEDYRDYFIRNLHDALSGHTSNNVAEAVKYSERSLTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDAGFKVVAHMMPDLPNMGLERDTDQFVEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYKSYPPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTQCRDVRTREVGIQEIHHKVRPYQIELIRRDYVANGGWETFLSYEDPEQDILVGLLRLRKCSEESFRPEL-----------KGGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMLLMEEAERIAKEEHGSWKIAVISGVGTRNYYRKIGYELEGPYMVKRL 545

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BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
Match: sp|Q5RIC0|ELP3_DANRE (Elongator complex protein 3 OS=Danio rerio OX=7955 GN=elp3 PE=2 SV=3)

HSP 1 Score: 931.013 bits (2405), Expect = 0.000e+0
Identity = 437/558 (78.32%), Postives = 497/558 (89.07%), Query Frame = 3

Query:   51 MGK-AKKVDKSQ-DGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGK  KK D S+ + MM TI+++I++L++A+ E + ++LNK+KTK S+K GL  QPRLVDII  VP  Y++ LVP+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S NV EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MGKPKKKSDLSRAELMMMTIADVIKQLVEAHEEGKDINLNKVKTKTSAKYGLSAQPRLVDIIAAVPPHYRRALVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNVTEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLGYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGMERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSALVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KGGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSSKLAVISGVGTRNYYRKMGYELEGPYMVKNL 547

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BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
Match: sp|Q5HZM6|ELP3_XENLA (Elongator complex protein 3 OS=Xenopus laevis OX=8355 GN=elp3 PE=2 SV=1)

HSP 1 Score: 924.08 bits (2387), Expect = 0.000e+0
Identity = 430/543 (79.19%), Postives = 490/543 (90.24%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGH+VDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH SKDAGFKVV+HMMPDLPN+G +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS E FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIARDEHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   17 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHNVDKVEFIVMGGTFMALPEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLCYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLSKDAGFKVVSHMMPDLPNMGLERDIEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEESFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIARDEHGSWKIAVISGVGTRNYYRKIGYELEGPYMVKRL 548

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BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
Match: sp|Q6NVL5|ELP3_XENTR (Elongator complex protein 3 OS=Xenopus tropicalis OX=8364 GN=elp3 PE=2 SV=1)

HSP 1 Score: 908.286 bits (2346), Expect = 0.000e+0
Identity = 429/543 (79.01%), Postives = 490/543 (90.24%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM T++++I++L++A+ + + V+LNKLKTK S+K GL  QPRLVDII  VP +Y+KILVP+LKAKP+R+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRD+FIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DG+K+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VPI+++DP+KFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   17 MMMTVADVIKQLVEAHEQGKDVNLNKLKTKTSAKYGLSAQPRLVDIIAAVPPQYRKILVPKLKAKPIRTASGIAVVAVMCKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALSEDYRDFFIRNLHDALSGHTSNSVSEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMAKDAGFKVVSHMMPDLPNVGLERDTEQFIEFFENPAFRPDGMKLYPTLVIRGTGLYELWKTGRYRSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEQSFRPEL-----------KGGVSIVRELHVYGSVVPISSRDPSKFQHQGFGMLLMEEAERIAREEHGSCKIAVISGVGTRNYYRKLGYELEGPYMVKKL 548

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BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
Match: sp|Q9H9T3|ELP3_HUMAN (Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2)

HSP 1 Score: 902.894 bits (2332), Expect = 0.000e+0
Identity = 434/557 (77.92%), Postives = 496/557 (89.05%), Query Frame = 3

Query:   51 MGKAKKVDKS-QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M + +K D S  + MM TI ++I++LI+A+ + + +DLNK+KTK ++K GL  QPRLVDII  VP +Y+K+L+P+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  EYRDYFIRNLHDALSGH S N+ EAVKYSERS TKC+GITIETRPDYC+K+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH +KD+GFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWK+ +Y SY P+ L++L+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG++CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDPDQDIL+GL RLR+CS E FR EL         G   G SI+RELHVYG+ VP++++DPTKFQHQGFG LL+EE+ERIAR+EHGS KIA+ISGVGTRNYYRK+GY L+GPYMVKML
Sbjct:    1 MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFEL--------GG---GVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKML 546

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BLAST of Elongator complex protein 3 vs. TrEMBL
Match: V3ZBA0 (Elongator complex protein 3 OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_193581 PE=3 SV=1)

HSP 1 Score: 949.503 bits (2453), Expect = 0.000e+0
Identity = 443/559 (79.25%), Postives = 499/559 (89.27%), Query Frame = 3

Query:   51 MGKAKK---VDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M KAKK       ++ MM T+SEI+ ELIKA  E + V+LNK+KT+ISSK GLP QPRLVDII  VPQ+YKK LVP+LKAKPVR+ASGI VVAVMCKPHRCPHI+MTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY+P+LQTRHR+EQL QLGHSVDKVEFIVMGGTFM+L  +YRDYFIRNLHDALSGH S NV EAVK+SE+S TKC+GITIETRPDYCLKKHLSDML YGCTRLEIGVQSVYED+ARDTNRGHTVKA CESF  SKDAGFKVV+HMMPDLPN+GW+RD  QF EFFENPAFRADGLKIYPTLVIRGTGLYELWKT +Y SYPP+VLIDL+ARILALVPPWTR+YR+QRDIPMPLVTSGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK++PY+ EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS E FRPEL           + GCS++RELHVYG+ VP++A+DPTKFQHQGFG LL+EE+ERIA++EHGS KI +ISGVGTRNYYRK+GYELEGPYM K+L
Sbjct:    1 MVKAKKKVPTASKEELMMMTVSEIVNELIKADQEGKDVNLNKVKTRISSKYGLPSQPRLVDIIAAVPQQYKKALVPKLKAKPVRTASGIAVVAVMCKPHRCPHIAMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPYLQTRHRVEQLQQLGHSVDKVEFIVMGGTFMSLPEDYRDYFIRNLHDALSGHTSCNVNEAVKFSEKSTTKCIGITIETRPDYCLKKHLSDMLNYGCTRLEIGVQSVYEDIARDTNRGHTVKATCESFQMSKDAGFKVVSHMMPDLPNIGWERDIEQFIEFFENPAFRADGLKIYPTLVIRGTGLYELWKTGRYKSYPPSVLIDLVARILALVPPWTRIYRVQRDIPMPLVTSGVEHGNLRELALARMKDLGTQCRDVRTREVGIQEIHHKVKPYEAELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSEETFRPEL-----------VGGCSVVRELHVYGSVVPVHARDPTKFQHQGFGMLLMEEAERIAKEEHGSWKIGVISGVGTRNYYRKIGYELEGPYMTKIL 548

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BLAST of Elongator complex protein 3 vs. TrEMBL
Match: A0A4Z2CNV8 (Elongator complex protein 3 OS=Schistosoma japonicum OX=6182 GN=EWB00_008783 PE=3 SV=1)

HSP 1 Score: 947.577 bits (2448), Expect = 0.000e+0
Identity = 442/559 (79.07%), Postives = 499/559 (89.27%), Query Frame = 3

Query:   51 MGKAKKVDKS--QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDI-AGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M KA+K+  +  ++ M+ T+SEII  L+KA  E R VDLNKLK+ I+SK GL  QPRLVD+I  VP E+K +L+P LKAKPVRSASGIVV+AVMCKPHRCPHI+MTGN+CVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY+PF+QTRHR+EQL QLGH+ DKVEFIVMGGTFM L  +YRDYFIRNLHDALSGH SQNV+EAV YSERS TKCVGITIETRPDYCLKKHL +ML+YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH SKDAGFKVV+HMMPDLPNVGW+RD AQFAE+FENPAFR+DGLKIYPTLVIRGTGLYELW+T +Y SYPP +LIDLIARILALVPPWTR+YRIQRDIPMPLVTSGV+HGNLR+L LARM ELG  CRDVRTREVG+QEI+ +++PYQ+EL+RRDYVANGGWETFL+YEDP QDIL+GL RLR+CS + FRPELL T   D      P CSI+RELHVYG+AVP+ A+DPTKFQHQGFG LL+EE+ERIA+ EHGS+KIA+ISGVGTRNYYRK+GYELEGPYM+K L
Sbjct:    1 MAKARKIPNATKEELMVLTVSEIIAHLLKAIEEKRDVDLNKLKSAIASKYGLASQPRLVDLIAAVPTEHKHVLLPHLKAKPVRSASGIVVIAVMCKPHRCPHIAMTGNVCVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPFIQTRHRIEQLQQLGHTCDKVEFIVMGGTFMCLSEDYRDYFIRNLHDALSGHTSQNVDEAVSYSERSRTKCVGITIETRPDYCLKKHLGEMLRYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLSKDAGFKVVSHMMPDLPNVGWERDLAQFAEYFENPAFRSDGLKIYPTLVIRGTGLYELWRTGRYKSYPPGMLIDLIARILALVPPWTRIYRIQRDIPMPLVTSGVEHGNLRELVLARMEELGASCRDVRTREVGIQEIHSRVKPYQVELIRRDYVANGGWETFLAYEDPYQDILIGLLRLRKCSPQTFRPELLATCIKDCQVNKDPRCSIVRELHVYGSAVPVAARDPTKFQHQGFGTLLMEEAERIAKYEHGSLKIAVISGVGTRNYYRKLGYELEGPYMIKFL 559

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BLAST of Elongator complex protein 3 vs. TrEMBL
Match: A0A5K3F7V9 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 944.495 bits (2440), Expect = 0.000e+0
Identity = 445/548 (81.20%), Postives = 494/548 (90.15%), Query Frame = 3

Query:   75 KSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            K ++ M+ TISEII EL+KA  ++R ++LNKLKT IS K GL  QPRLVDII  VP +++ +L+P+LKAKPVRSASGIVVVAVMCKPHRCPHI+MTGN+CVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY P++QTRHR+EQL QLGHS DKVEFIVMGGTFM L  EYRDYFIRNLHDALSGH S+NV EAV YSE+S TKC+GITIETRPDYCLKKHL +ML YGCTRLEIGVQSVYEDVARDTNRGHTV AVCESFH SKDAGFKV+AHMMPDLPNVGW+RD AQFAE+FENPAFR+DGLKIYPTLVIRGTGLYELW+T +Y+SYPPN+LIDLIARILALVPPWTRVYRIQRDIPMPLVTSGV+HGNLR+LALARM ELG KCRDVRTREVG+QEI+  ++P QIEL+RRDYVANGGWETFL+YEDP QDILVGL RLR+CS E FRPEL    +     D P CSI+RELHVYG+AVP++AKDPTKFQHQGFG LL+EE+ERIARDEHGSVKIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:   12 KKEELMIMTISEIISELLKAVKDHRDINLNKLKTSISRKYGLSSQPRLVDIISAVPPQHRYVLLPKLKAKPVRSASGIVVVAVMCKPHRCPHIAMTGNVCVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYHPYVQTRHRIEQLQQLGHSCDKVEFIVMGGTFMCLPEEYRDYFIRNLHDALSGHTSKNVAEAVYYSEKSKTKCIGITIETRPDYCLKKHLGEMLNYGCTRLEIGVQSVYEDVARDTNRGHTVNAVCESFHLSKDAGFKVIAHMMPDLPNVGWERDLAQFAEYFENPAFRSDGLKIYPTLVIRGTGLYELWRTGRYSSYPPNMLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVEHGNLRELALARMAELGAKCRDVRTREVGIQEIHKNVQPSQIELIRRDYVANGGWETFLAYEDPHQDILVGLLRLRKCSPETFRPELRCRGEIGDDDDDPLCSIVRELHVYGSAVPVSAKDPTKFQHQGFGTLLMEEAERIARDEHGSVKIAVISGVGTRNYYRKLGYELEGPYMVKSL 559

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BLAST of Elongator complex protein 3 vs. TrEMBL
Match: G4M0F5 (Elongator complex protein 3 OS=Schistosoma mansoni OX=6183 GN=Smp_085500 PE=3 SV=1)

HSP 1 Score: 944.11 bits (2439), Expect = 0.000e+0
Identity = 441/563 (78.33%), Postives = 503/563 (89.34%), Query Frame = 3

Query:   51 MGKAKKVDKS--QDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELL----PTDKSDIAGDL-PGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M KA+K+  +  ++ M+ T+SEII  L+KA  E R VDLNKLK+ ISSK GL  QPRLVD+I  VP E++ +L+P LKAKPVRSASGIVV+AVMCKPHRCPHI++TGN+CVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY+PF+QTRHR+EQL QLGH+ DKVEFIVMGGTFM L  +YRDYFIR+LHDALSGH SQNV+EAV YSERS TKCVGITIETRPDYCLKKHLS+ML+YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH SKDAGFKVV+HMMPDLPNVGW+RD AQFAE+FENPAFR+DGLKIYPTLVIRGTGLYELW+T +Y SYPP +LIDLIARILALVPPWTR+YRIQRDIPMPLVTSGV+HGNLR+L LARM ELG  CRDVRTREVG+QEI+ +++PYQ+ELVRRDYVANGGWETFL+YEDP QDIL+GL RLR+CS + FRPEL+      D  D+ G+  P CSI+RELHVYG+AVP+ A+DPTKFQHQGFG LL+EE+ERIA+ EHGS+KIA+ISGVGTRNYYRK+GY+LEGPYM+K L
Sbjct:    1 MAKARKIPNATKEELMVLTVSEIISHLLKAIEEKRDVDLNKLKSVISSKYGLASQPRLVDLIAAVPTEHRHVLLPHLKAKPVRSASGIVVIAVMCKPHRCPHIAVTGNVCVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPFIQTRHRIEQLQQLGHTCDKVEFIVMGGTFMCLSEDYRDYFIRSLHDALSGHTSQNVDEAVSYSERSKTKCVGITIETRPDYCLKKHLSEMLRYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLSKDAGFKVVSHMMPDLPNVGWERDLAQFAEYFENPAFRSDGLKIYPTLVIRGTGLYELWRTGRYKSYPPGMLIDLIARILALVPPWTRIYRIQRDIPMPLVTSGVEHGNLRELVLARMEELGASCRDVRTREVGIQEIHSRVKPYQVELVRRDYVANGGWETFLAYEDPYQDILIGLLRLRKCSLQTFRPELIVKTHNNDDDDVQGNKDPRCSIVRELHVYGSAVPVAARDPTKFQHQGFGTLLMEEAERIAKYEHGSLKIAVISGVGTRNYYRKLGYKLEGPYMIKFL 563

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BLAST of Elongator complex protein 3 vs. TrEMBL
Match: A0A3S1BA26 (Elongator complex protein 3 OS=Elysia chlorotica OX=188477 GN=EGW08_012919 PE=3 SV=1)

HSP 1 Score: 940.258 bits (2429), Expect = 0.000e+0
Identity = 444/560 (79.29%), Postives = 499/560 (89.11%), Query Frame = 3

Query:   51 MGKAKKV---DKSQDGMM-RTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGK KK    D S++ +M   ++EI+ EL+KA  EN+ VDLNKLKTKI+S+  +  QPRLVDII  VPQEYKK+L+P+LKAKPVR+ASGI VVAVMCKPHRCPHI+MTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY+P+LQTRHR+EQL QLGHSVDKVEFIVMGGTFM+L  +YRDYFIRNLHDALSGH S NV+EAVKYSERS TKC+GITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESF  SKDAGFKVV+HMMPDLPNVGW+RD  QF EFFENPAFRADGLKIYPTLVIRGTGLYELWKT +Y SYPP+ L+DLIARILALVPPWTRVYR+QRDIPMPLVTSGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK++P Q EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS++ FR EL             GCSI+RELHVYG+ VP++A+DP KFQHQGFG LL+EE+ RIA++EHG+ KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:    1 MGKNKKKVVNDLSKEEIMVMAVAEIVSELVKAVRENKDVDLNKLKTKIASRYNMSSQPRLVDIIAAVPQEYKKMLLPKLKAKPVRTASGIAVVAVMCKPHRCPHIAMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPYLQTRHRVEQLQQLGHSVDKVEFIVMGGTFMSLPDDYRDYFIRNLHDALSGHTSSNVQEAVKYSERSTTKCIGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFQMSKDAGFKVVSHMMPDLPNVGWERDIEQFIEFFENPAFRADGLKIYPTLVIRGTGLYELWKTGRYKSYPPSQLVDLIARILALVPPWTRVYRVQRDIPMPLVTSGVEHGNLRELALARMADLGTQCRDVRTREVGIQEIHHKVKPDQAELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSADTFRAEL-----------RGGCSIVRELHVYGSVVPVHARDPRKFQHQGFGILLMEEAARIAKEEHGAKKIAVISGVGTRNYYRKLGYELEGPYMVKGL 549

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BLAST of Elongator complex protein 3 vs. Ensembl Cavefish
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:103039785])

HSP 1 Score: 931.784 bits (2407), Expect = 0.000e+0
Identity = 434/558 (77.78%), Postives = 495/558 (88.71%), Query Frame = 3

Query:   51 MGKAKKVDK--SQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGK K+  +    + MM TI+++I++L++A+ + + +DLNKLKTK S+K GL  QPRLVDII  VP  Y++ LVP+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRDYFIRNLHDALSGH S NV EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MGKPKRKSELSRAELMMMTIADVIKQLVEAHEQGKDIDLNKLKTKTSAKYGLSAQPRLVDIIAAVPPHYRRALVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALAEDYRDYFIRNLHDALSGHTSNNVAEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLAYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGIERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KAGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSGKLAVISGVGTRNYYRKMGYELEGPYMVKRL 547

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BLAST of Elongator complex protein 3 vs. Ensembl Cavefish
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:103039785])

HSP 1 Score: 929.858 bits (2402), Expect = 0.000e+0
Identity = 430/543 (79.19%), Postives = 488/543 (89.87%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MM TI+++I++L++A+ + + +DLNKLKTK S+K GL  QPRLVDII  VP  Y++ LVP+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRDYFIRNLHDALSGH S NV EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:   14 MMMTIADVIKQLVEAHEQGKDIDLNKLKTKTSAKYGLSAQPRLVDIIAAVPPHYRRALVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALAEDYRDYFIRNLHDALSGHTSNNVAEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLAYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGIERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KAGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSGKLAVISGVGTRNYYRKMGYELEGPYMVKRL 545

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Cavefish
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:103039785])

HSP 1 Score: 889.412 bits (2297), Expect = 0.000e+0
Identity = 412/536 (76.87%), Postives = 474/536 (88.43%), Query Frame = 3

Query:   51 MGKAKKVDK--SQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGV 1652
            MGK K+  +    + MM TI+++I++L++A+ + + +DLNKLKTK S+K GL  QPRLVDII  VP  Y++ LVP+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRDYFIRNLHDALSGH S NV EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+EL+RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISG+
Sbjct:    1 MGKPKRKSELSRAELMMMTIADVIKQLVEAHEQGKDIDLNKLKTKTSAKYGLSAQPRLVDIIAAVPPHYRRALVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALAEDYRDYFIRNLHDALSGHTSNNVAEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLAYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGIERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYSPSTLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTECRDVRTREVGIQEIHHKVRPYQVELIRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KAGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSGKLAVISGI 525

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BLAST of Elongator complex protein 3 vs. Ensembl Sea Lamprey
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:541509])

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 262/355 (73.80%), Postives = 302/355 (85.07%), Query Frame = 3

Query:  663 KYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQ---GFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            +YSERS TKC+GITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFH SKDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK++PY++EL+RRDYVANGGWETFL+YEDP QD+LVGL RLR+CS + FRPEL             G SI+RELHVYG+ VP++A+DPTKFQHQ    FG     E+  I     G + +A+ +G+GTR+YYRK+GYELEGPYMVK L
Sbjct:    1 RYSERSKTKCIGITIETRPDYCLKRHLSDMLGYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHMSKDAGFKVVSHMMPDLPNVGMERDLEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYTPSGLVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTECRDVRTREVGIQEIHHKVKPYEVELIRRDYVANGGWETFLAYEDPRQDVLVGLLRLRRCSPDSFRPEL-----------KGGVSIVRELHVYGSVVPVSARDPTKFQHQRAMSFGNYTCTEASFIHCLNQGIILLAVCAGIGTRDYYRKIGYELEGPYMVKKL 344

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BLAST of Elongator complex protein 3 vs. Ensembl Yeast
Match: ELP3 (Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin; human homolog ELP3 can partially complement yeast elp3 null mutant [Source:SGD;Acc:S000006007])

HSP 1 Score: 806.979 bits (2083), Expect = 0.000e+0
Identity = 380/555 (68.47%), Postives = 455/555 (81.98%), Query Frame = 3

Query:   63 KKVDKSQDGMMRTISEIIEELIKAYHE--NRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSE-IFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            KK+   ++  ++  ++I  EL  +      R ++LN L TK S K  L  QPRL DII  +P +YKK L+P+LKAKPVR+ASGI VVAVMCKPHRCPHI+ TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+ Q R R+EQL QLGHS+DKVE+++MGGTFM+L  EYR+ FI  LH+ALSG    +++EA+ YS++S TKCVGITIETRPDYC + HL DMLKYGCTRLEIGVQS+YEDVARDTNRGHTV++VCE+F  SKDAG+KVV+HMMPDLPNVG +RD  QF E+FENP FR DGLKIYPTLVIRGTGLYELWKT +Y SY  N L+DL+ARILALVPPWTR+YR+QRDIPMPLVTSGVD+GNLR+LALARM +LG  CRDVRTREVG+QE++HK++P Q+EL+RRDY ANGGWETFLSYEDP +DIL+GL RLR+ S +  +R E                SI+RELHVYG+ VP++++DP KFQHQGFG LL+EE+ERIA++EHGS KI++ISGVG RNYY K+GYEL+GPYM K +
Sbjct:   13 KKLAPEKERFIQCCADITLELTDSLTSGTTREINLNGLITKYSKKYKLKQQPRLTDIINSIPDQYKKYLLPKLKAKPVRTASGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQARGRVEQLKQLGHSIDKVEYVLMGGTFMSLPKEYREDFIVKLHNALSGFNGNDIDEAILYSQQSLTKCVGITIETRPDYCTQTHLDDMLKYGCTRLEIGVQSLYEDVARDTNRGHTVRSVCETFAVSKDAGYKVVSHMMPDLPNVGMERDIEQFKEYFENPDFRTDGLKIYPTLVIRGTGLYELWKTGRYKSYSANALVDLVARILALVPPWTRIYRVQRDIPMPLVTSGVDNGNLRELALARMKDLGTTCRDVRTREVGIQEVHHKVQPDQVELIRRDYYANGGWETFLSYEDPKKDILIGLLRLRKASKKYTYRKEFTSQR----------TSIVRELHVYGSVVPLHSRDPRKFQHQGFGTLLMEEAERIAKEEHGSEKISVISGVGVRNYYGKLGYELDGPYMSKRI 557

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Nematostella
Match: EDO39414 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA82])

HSP 1 Score: 907.131 bits (2343), Expect = 0.000e+0
Identity = 434/559 (77.64%), Postives = 494/559 (88.37%), Query Frame = 3

Query:   51 MGKAKK---VDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGK  K   V    + M+ T+S+I+ +LI A+ +   ++LNK+K K +SK GL  QPRLVDII  +P  ++K+L+P+LKAKPVR+ASGI VVAVMCKPHRCPHI+MTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARY+P+LQT+HR+EQL QLGHSVDKVEFIVMGGTFM LD  YRD+FIRNLHDALSGH S NVEEAVKYSERS TKC+GITIETRPDYCLKKHLS ML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH SKDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFRADGLKIYPTLVIRGTGLYELWKT +Y SYPPN L+DLIARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RP++IE +RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL   D+         CSI+RELHVYG+ VP++A+DP+KFQHQGFG LL+EE+ERIAR+EHGS+KIA+ISGVGTRNYYRK+GYELEGPYMVK L
Sbjct:    1 MGKKNKKEPVASRAELMVMTVSDIVNQLITAHEKGENINLNKVKGKAASKYGLASQPRLVDIIAAIPHSHRKVLLPKLKAKPVRTASGIAVVAVMCKPHRCPHINMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPYLQTKHRVEQLKQLGHSVDKVEFIVMGGTFMCLDEGYRDFFIRNLHDALSGHTSNNVEEAVKYSERSKTKCIGITIETRPDYCLKKHLSSMLAYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHQSKDAGFKVVSHMMPDLPNVGLERDIDQFIEFFENPAFRADGLKIYPTLVIRGTGLYELWKTGRYKSYPPNTLVDLIARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTQCRDVRTREVGIQEIHHKVRPFEIEQIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSDQSFRPEL--KDR---------CSIVRELHVYGSVVPVSARDPSKFQHQGFGMLLMEEAERIAREEHGSIKIAVISGVGTRNYYRKLGYELEGPYMVKSL 548

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Nematostella
Match: EDO42840 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S098])

HSP 1 Score: 827.009 bits (2135), Expect = 0.000e+0
Identity = 402/543 (74.03%), Postives = 468/543 (86.19%), Query Frame = 3

Query:   90 MMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            M+ T+S+I+ +LI A+ +   V+LNK+K K +SK GL  QPRLVDII  +P  ++K+L+P+LKAKPVR+ASGI VVAVMCKPHRCPHI+MTGNICV       + F +  + +  ++PTSMRAIRARY+P+LQT+HR+EQL QLGHSVDKVEFIVMGGTFM LD  YRD+FIRNLHDALSGH S NVEEAVKYSERS TKC+GITIETRPDYCLKKHLS ML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH SKDAGFKVV+HMMPDLPNVG +RD  QF EFFENPAFRADGLKIYPTLVIRGTGLYELWKT +Y SYPPN L+DLIARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM +LG +CRDVRTREVG+QEI+HK+RP++IE +RRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL   D+         CSI+RELHVYG+ VP++A+DP+KFQHQGFG LL+EE+ERIAR+EHGS+KIA+ISG     + +K+GYELEGPYMVK L
Sbjct:    1 MVMTVSDIVNQLITAHEKGENVNLNKVKGKAASKYGLASQPRLVDIIAAIPHSHRKVLLPKLKAKPVRTASGIAVVAVMCKPHRCPHINMTGNICVLFHDVALNVFLF--EFHLLWQPTSMRAIRARYNPYLQTKHRVEQLKQLGHSVDKVEFIVMGGTFMCLDEGYRDFFIRNLHDALSGHTSNNVEEAVKYSERSKTKCIGITIETRPDYCLKKHLSSMLAYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHQSKDAGFKVVSHMMPDLPNVGLERDIDQFIEFFENPAFRADGLKIYPTLVIRGTGLYELWKTGRYKSYPPNTLVDLIARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTQCRDVRTREVGIQEIHHKVRPFEIEQIRRDYVANGGWETFLSYEDPEQDILIGLLRLRKCSDQSFRPEL--KDR---------CSIVRELHVYGSVVPVSARDPSKFQHQGFGMLLMEEAERIAREEHGSIKIAVISG----EWNQKLGYELEGPYMVKSL 526

[Close]

BLAST of Elongator complex protein 3 vs. Ensembl Medaka
Match: elp3 (elongator acetyltransferase complex subunit 3 [Source:NCBI gene;Acc:101166352])

HSP 1 Score: 931.398 bits (2406), Expect = 0.000e+0
Identity = 436/558 (78.14%), Postives = 500/558 (89.61%), Query Frame = 3

Query:   51 MGKAK-KVDKSQ-DGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGK K K D+S+ + MM TI+++I++L++A+ E + ++LNK+KTK S+K GL  QPRLVDII  VP +Y+++LVP+LKAKP+R+ASGI VVAVMCKPHRCPHIS TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDP+LQTRHR+EQL QLGHSVDKVEFIVMGGTFMAL  +YRDYFIRNLHDALSGH S +V EAV+YSERSNTKCVGITIETRPDYCLK+HLSDML YGCTRLEIGVQSVYEDVARDTNRGHTV+AVCESFH +KDAGFKVVAHMMPDLPNVG +RD  QF EFFENPAFR DGLK+YPTLVIRGTGLYELWKT +Y SY P+ L+DL+ARILALVPPWTRVYR+QRDIPMPLV+SGV+HGNLR+LALARM ++G +CRDVRTREVG+QEI+HK+RPYQ+ELVRRDYVANGGWETFLSYEDP+QDIL+GL RLR+CS + FRPEL             G SI+RELHVYG+ VP++++DP+KFQHQGFG +L+EE+ERIARDEHGS K+A+ISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MGKPKRKSDQSRAELMMMTIADVIKQLVEAHEEGKDINLNKVKTKTSAKYGLEAQPRLVDIIAAVPPQYRRVLVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMALPEDYRDYFIRNLHDALSGHTSNSVAEAVRYSERSNTKCVGITIETRPDYCLKRHLSDMLNYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFHLAKDAGFKVVAHMMPDLPNVGMERDVEQFIEFFENPAFRPDGLKLYPTLVIRGTGLYELWKTGRYKSYTPSALVDLVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDMGTQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPEQDILIGLLRLRRCSPQSFRPEL-----------KGGVSIVRELHVYGSVVPVSSRDPSKFQHQGFGMMLMEEAERIARDEHGSGKLAVISGVGTRNYYRKMGYELEGPYMVKDL 547

[Close]

BLAST of Elongator complex protein 3 vs. Planmine SMEST
Match: SMESG000011834.1 (SMESG000011834.1)

HSP 1 Score: 1154.04 bits (2984), Expect = 0.000e+0
Identity = 554/556 (99.64%), Postives = 554/556 (99.64%), Query Frame = 3

Query:   51 MGKAKKVDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGKAKKVDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSE FRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MGKAKKVDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSETFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKTL 556

[Close]

BLAST of Elongator complex protein 3 vs. Planmine SMEST
Match: SMESG000011834.1 (SMESG000011834.1)

HSP 1 Score: 1150.19 bits (2974), Expect = 0.000e+0
Identity = 554/557 (99.46%), Postives = 554/557 (99.46%), Query Frame = 3

Query:   51 MGKAKKV-DKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKML 1718
            MGKAKKV DKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSE FRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVK L
Sbjct:    1 MGKAKKVVDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGLPYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPHISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRLEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNVEEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQFAEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIARILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDVRTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLCRLRQCSSETFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPTKFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGPYMVKTL 557

The following BLAST results are available for this feature:

BLAST of Elongator complex protein 3 vs. Ensembl Human
BLAST of Elongator complex protein 3 vs. Ensembl Celegans
BLAST of Elongator complex protein 3 vs. Ensembl Fly
BLAST of Elongator complex protein 3 vs. Ensembl Zebrafish
BLAST of Elongator complex protein 3 vs. Ensembl Xenopus
BLAST of Elongator complex protein 3 vs. Ensembl Mouse
BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
BLAST of Elongator complex protein 3 vs. TrEMBL
BLAST of Elongator complex protein 3 vs. Ensembl Cavefish
BLAST of Elongator complex protein 3 vs. Ensembl Sea Lamprey
BLAST of Elongator complex protein 3 vs. Ensembl Yeast
BLAST of Elongator complex protein 3 vs. Ensembl Nematostella
BLAST of Elongator complex protein 3 vs. Ensembl Medaka
BLAST of Elongator complex protein 3 vs. Planmine SMEST

BLAST of Elongator complex protein 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ELP3	0.000e+0	77.92	elongator acetyltransferase complex subunit 3 [Sou...	[more]
ELP3	0.000e+0	79.19	elongator acetyltransferase complex subunit 3 [Sou...	[more]
ELP3	0.000e+0	82.27	elongator acetyltransferase complex subunit 3 [Sou...	[more]
ELP3	0.000e+0	82.58	elongator acetyltransferase complex subunit 3 [Sou...	[more]
ELP3	0.000e+0	81.22	elongator acetyltransferase complex subunit 3 [Sou...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
elpc-3	0.000e+0	73.48	Probable elongator complex protein 3 [Source:UniP...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Elp3	0.000e+0	76.68	gene:FBgn0031604 transcript:FBtr0077439	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
elp3	0.000e+0	79.19	elongator acetyltransferase complex subunit 3 [Sou...	[more]
elp3	0.000e+0	82.58	elongator acetyltransferase complex subunit 3 [Sou...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gucd1	0.000e+0	79.01	guanylyl cyclase domain containing 1 [Source:Xenba...	[more]
gucd1	0.000e+0	79.01	guanylyl cyclase domain containing 1 [Source:Xenba...	[more]
gucd1	0.000e+0	79.01	guanylyl cyclase domain containing 1 [Source:Xenba...	[more]
gucd1	0.000e+0	79.01	guanylyl cyclase domain containing 1 [Source:Xenba...	[more]
gucd1	0.000e+0	79.01	guanylyl cyclase domain containing 1 [Source:Xenba...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Elp3	0.000e+0	78.45	elongator acetyltransferase complex subunit 3 [Sou...	[more]
Elp3	0.000e+0	77.20	elongator acetyltransferase complex subunit 3 [Sou...	[more]
Elp3	0.000e+0	76.78	elongator acetyltransferase complex subunit 3 [Sou...	[more]

BLAST of Elongator complex protein 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5ZHS1\|ELP3_CHICK	0.000e+0	78.60	Elongator complex protein 3 OS=Gallus gallus OX=90...	[more]
sp\|Q5RIC0\|ELP3_DANRE	0.000e+0	78.32	Elongator complex protein 3 OS=Danio rerio OX=7955...	[more]
sp\|Q5HZM6\|ELP3_XENLA	0.000e+0	79.19	Elongator complex protein 3 OS=Xenopus laevis OX=8...	[more]
sp\|Q6NVL5\|ELP3_XENTR	0.000e+0	79.01	Elongator complex protein 3 OS=Xenopus tropicalis ...	[more]
sp\|Q9H9T3\|ELP3_HUMAN	0.000e+0	77.92	Elongator complex protein 3 OS=Homo sapiens OX=960...	[more]

BLAST of Elongator complex protein 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V3ZBA0	0.000e+0	79.25	Elongator complex protein 3 OS=Lottia gigantea OX=...	[more]
A0A4Z2CNV8	0.000e+0	79.07	Elongator complex protein 3 OS=Schistosoma japonic...	[more]
A0A5K3F7V9	0.000e+0	81.20	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
G4M0F5	0.000e+0	78.33	Elongator complex protein 3 OS=Schistosoma mansoni...	[more]
A0A3S1BA26	0.000e+0	79.29	Elongator complex protein 3 OS=Elysia chlorotica O...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
elp3	0.000e+0	77.78	elongator acetyltransferase complex subunit 3 [Sou...	[more]
elp3	0.000e+0	79.19	elongator acetyltransferase complex subunit 3 [Sou...	[more]
elp3	0.000e+0	76.87	elongator acetyltransferase complex subunit 3 [Sou...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
elp3	0.000e+0	73.80	elongator acetyltransferase complex subunit 3 [Sou...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ELP3	0.000e+0	68.47	Subunit of Elongator complex; Elongator is require...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO39414	0.000e+0	77.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42840	0.000e+0	74.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Elongator complex protein 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
elp3	0.000e+0	78.14	elongator acetyltransferase complex subunit 3 [Sou...	[more]

BLAST of Elongator complex protein 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000011834.1	0.000e+0	99.64	SMESG000011834.1	[more]
SMESG000011834.1	0.000e+0	99.46	SMESG000011834.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30012263 ID=SMED30012263|Name=Elongator complex protein 3|organism=Schmidtea mediterranea sexual|type=transcript|length=1809bp
GAAATTTTGTTTTAATATTGCTTTCCAAATAATTGATTTGTTAATAATTG
ATGGGTAAAGCTAAAAAAGTCGACAAAAGCCAAGATGGCATGATGAGAAC
AATCTCTGAAATAATTGAAGAATTAATTAAAGCATACCATGAAAATCGAA
CTGTTGATTTAAATAAATTGAAAACTAAAATTTCTTCAAAGAATGGTTTG
CCATATCAACCCAGACTTGTTGATATAATCGGCGGTGTACCCCAAGAATA
TAAAAAAATTTTAGTTCCCAGATTGAAAGCAAAACCTGTTCGGTCAGCCA
GTGGAATTGTTGTTGTCGCTGTCATGTGCAAGCCTCATAGATGTCCCCAT
ATTAGCATGACAGGAAATATCTGCGTATATTGTCCAGGGGGTCCGGATTC
CGATTTTGAATATTCCACGCAGTCTTATACTGGTTATGAGCCGACATCAA
TGAGAGCAATTAGAGCTCGATATGATCCATTTTTACAAACTCGACATCGT
CTCGAACAGTTGGCTCAGTTGGGTCACAGTGTTGATAAGGTTGAATTCAT
TGTGATGGGGGGAACATTTATGGCTCTCGATACTGAATATCGGGATTATT
TCATTCGAAATCTCCATGATGCATTGTCTGGCCACCGGAGTCAGAATGTT
GAGGAAGCGGTAAAATACTCGGAGCGCAGTAATACAAAGTGTGTCGGCAT
AACCATTGAAACTCGACCGGATTATTGCTTGAAGAAGCATTTGAGTGACA
TGTTGAAATATGGTTGCACCAGGCTAGAAATTGGAGTTCAGAGTGTCTAT
GAAGACGTTGCTAGGGACACTAATAGAGGTCACACCGTAAAGGCTGTTTG
CGAGTCGTTTCATTTCAGTAAAGATGCCGGATTTAAAGTAGTTGCTCACA
TGATGCCTGACTTGCCAAATGTTGGATGGGATAGAGATCAAGCCCAATTT
GCTGAATTTTTTGAAAATCCAGCATTTCGGGCTGACGGCTTGAAAATCTA
CCCGACACTGGTTATCAGGGGCACAGGCTTATATGAGTTATGGAAAACGA
AAAAGTACAATAGTTACCCGCCTAATGTTTTGATTGATTTGATTGCTCGC
ATTCTTGCATTGGTTCCACCGTGGACTCGGGTTTATCGTATCCAGCGCGA
TATCCCGATGCCTCTTGTTACAAGTGGTGTCGATCACGGAAATCTGCGCC
AGCTGGCGTTAGCAAGAATGAACGAACTCGGTGTGAAGTGTCGAGACGTT
AGAACGAGAGAAGTCGGAATGCAGGAGATTAATCACAAAATTCGACCTTA
TCAAATTGAACTCGTTAGGAGGGATTATGTTGCTAACGGCGGATGGGAAA
CTTTTCTCTCTTATGAAGATCCCGATCAGGATATTCTTGTTGGTTTGTGT
CGATTGCGACAGTGTTCATCGGAAATCTTTCGACCGGAGTTGTTGCCCAC
TGATAAATCTGACATCGCCGGAGATTTACCCGGCTGTTCAATCATCAGGG
AGTTGCACGTGTACGGTACAGCTGTGCCGATCAATGCAAAGGATCCAACA
AAGTTTCAGCATCAAGGATTCGGGAAACTGTTAATCGAAGAATCAGAAAG
GATAGCTCGAGATGAACATGGCTCTGTGAAAATTGCGATTATATCTGGAG
TGGGAACGAGAAATTATTACCGTAAAATGGGCTATGAACTCGAGGGACCT
TATATGGTGAAAATGTTATAAAGGAATAAAAATTGACTTTTTTTTGTGTT
TGGCTGAACTCGTAAATAAAACCGGAAATTTGTGAACATATAAAACTAAA
TTAAAAAAA

protein sequence of SMED30012263-orf-1

>SMED30012263-orf-1 ID=SMED30012263-orf-1|Name=SMED30012263-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=557bp
MGKAKKVDKSQDGMMRTISEIIEELIKAYHENRTVDLNKLKTKISSKNGL
PYQPRLVDIIGGVPQEYKKILVPRLKAKPVRSASGIVVVAVMCKPHRCPH
ISMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHR
LEQLAQLGHSVDKVEFIVMGGTFMALDTEYRDYFIRNLHDALSGHRSQNV
EEAVKYSERSNTKCVGITIETRPDYCLKKHLSDMLKYGCTRLEIGVQSVY
EDVARDTNRGHTVKAVCESFHFSKDAGFKVVAHMMPDLPNVGWDRDQAQF
AEFFENPAFRADGLKIYPTLVIRGTGLYELWKTKKYNSYPPNVLIDLIAR
ILALVPPWTRVYRIQRDIPMPLVTSGVDHGNLRQLALARMNELGVKCRDV
RTREVGMQEINHKIRPYQIELVRRDYVANGGWETFLSYEDPDQDILVGLC
RLRQCSSEIFRPELLPTDKSDIAGDLPGCSIIRELHVYGTAVPINAKDPT
KFQHQGFGKLLIEESERIARDEHGSVKIAIISGVGTRNYYRKMGYELEGP
YMVKML*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0051539	4 iron, 4 sulfur cluster binding
GO:0003824	catalytic activity
GO:0051536	iron-sulfur cluster binding
GO:0008080	N-acetyltransferase activity
GO:0004402	histone acetyltransferase activity
GO:0008607	phosphorylase kinase regulator activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0008033	tRNA processing
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0016573	histone acetylation
GO:0045859	regulation of protein kinase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR034687	ELP3-like
IPR039661	ELP3
IPR006638	Elp3/MiaB/NifB
IPR032432	Radical_SAM_C
IPR016181	Acyl_CoA_acyltransferase
IPR007197	rSAM
IPR005910	Hist_AcTrfase_ELP3
IPR000182	GNAT_dom
IPR023404	rSAM_horseshoe
IPR004039	Rubredoxin-type_fold

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0008023	transcription elongation factor complex

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006638	Elp3/MiaB/NifB	SMART	SM00729	MiaB	coord: 88..350 e-value: 2.8E-32 score: 123.2
IPR034687	Elongator complex protein 3-like	TIGRFAM	TIGR01211	TIGR01211	coord: 22..556 e-value: 2.1E-218 score: 724.0
IPR034687	Elongator complex protein 3-like	PIRSF	PIRSF005669	HAT_Elp3	coord: 1..556 e-value: 6.9E-246 score: 814.5
IPR034687	Elongator complex protein 3-like	SFLD	SFLDF00344	ELP3-like	coord: 36..556 e-value: 0.0 score: 644.2
IPR034687	Elongator complex protein 3-like	PANTHER	PTHR11135:SF0	ELONGATOR COMPLEX PROTEIN 3	coord: 7..556
None	No IPR available	GENE3D	G3DSA:3.40.630.30		coord: 400..556 e-value: 3.4E-6 score: 29.4
None	No IPR available	CDD	cd01335	Radical_SAM	coord: 95..341 e-value: 5.63391E-12 score: 63.1213
None	No IPR available	SUPERFAMILY	SSF102114	Radical SAM enzymes	coord: 118..357
IPR032432	Radical SAM, C-terminal extension	PFAM	PF16199	Radical_SAM_C	coord: 312..391 e-value: 3.5E-31 score: 107.1
IPR023404	Radical SAM, alpha/beta horseshoe	GENE3D	G3DSA:3.80.30.20		coord: 100..353 e-value: 8.1E-12 score: 46.6
IPR000182	GNAT domain	PFAM	PF00583	Acetyltransf_1	coord: 397..545 e-value: 5.8E-7 score: 29.7
IPR000182	GNAT domain	PROSITE	PS51186	GNAT	coord: 395..556 score: 9.757
IPR007197	Radical SAM	PFAM	PF04055	Radical_SAM	coord: 106..294 e-value: 3.6E-19 score: 69.7
IPR007197	Radical SAM	SFLD	SFLDS00029	Radical_SAM	coord: 36..556 e-value: 0.0 score: 644.2
IPR039661	ELP3/YhcC	PANTHER	PTHR11135	HISTONE ACETYLTRANSFERASE-RELATED	coord: 7..556
IPR016181	Acyl-CoA N-acyltransferase	SUPERFAMILY	SSF55729	Acyl-CoA N-acyltransferases (Nat)	coord: 354..552