Dual specificity tyrosine-phosphorylation-regulated kinase 1A
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012260 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10Note: Hover over icons to view figure legend
Homology
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Human
Match: DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:HGNC:3091]) HSP 1 Score: 398.667 bits (1023), Expect = 3.389e-125 Identity = 200/371 (53.91%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWN-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Human
Match: DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:HGNC:3091]) HSP 1 Score: 398.667 bits (1023), Expect = 3.640e-125 Identity = 200/371 (53.91%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWN-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Human
Match: DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:HGNC:3091]) HSP 1 Score: 399.438 bits (1025), Expect = 1.699e-124 Identity = 200/371 (53.91%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWN-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Human
Match: DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:HGNC:3091]) HSP 1 Score: 398.667 bits (1023), Expect = 1.734e-124 Identity = 200/371 (53.91%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWN-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Human
Match: DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:HGNC:3091]) HSP 1 Score: 400.593 bits (1028), Expect = 2.419e-123 Identity = 200/371 (53.91%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 110 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWN-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 458
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Celegans
Match: mbk-1 (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8WQL7]) HSP 1 Score: 378.252 bits (970), Expect = 8.289e-114 Identity = 189/358 (52.79%), Postives = 244/358 (68.16%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSM--DLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y++K GE++ RY + D +G GSFGQV +A D + E VAIKII+N+++F QA+ EI LL + + +D IV LK HF++R HLCLVFELL+Y+LY+LLKNTSF GVSLNL +KF QL L FLS P L IIHCDLKPENVLLV+ KRS I+V+DFGSSC+ R+Y YIQSRFYR+PEVLL + Y+ IDMWSLGCILVE+HTG+PLF G E +Q+++I+EV GMPP M+ + +KYF ++E + I + K RDG R ++ GARKL I+G +GGP GRR EPGHS +DY+ F DLI RML DP +RI+P ++HPF
Sbjct: 313 DYILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKY---------NIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTE---------DGIYYCKKT---RDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFL 649
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Celegans
Match: mbk-2 (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTF3]) HSP 1 Score: 243.047 bits (619), Expect = 7.664e-70 Identity = 146/344 (42.44%), Postives = 192/344 (55.81%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
RY + +IG GSFGQV++A D + VA+K++RN + F +QA+ EIR+L L + D G + I+ + +F +R H C+ FELL+ +LYEL+K F G SL L +KF + L L + L IHCDLKPENVLL RS IKV+DFGSSC ++R+Y YIQSRFYRAPEV+L Y M IDMWSLGCIL EL TG PL G+ E++Q+ IIE+ GMPP + +KRA + FI S+ A + V KR G A + S G DE F+D + R L DP R+TP +ALKH +
Sbjct: 133 RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSD---------GTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRL--IHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAKRA-RTFITSK-GYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMG-------DE---------LFVDFLKRCLDWDPETRMTPAQALKHKWL 447
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Celegans
Match: mbk-2 (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTF3]) HSP 1 Score: 243.047 bits (619), Expect = 7.664e-70 Identity = 146/344 (42.44%), Postives = 192/344 (55.81%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
RY + +IG GSFGQV++A D + VA+K++RN + F +QA+ EIR+L L + D G + I+ + +F +R H C+ FELL+ +LYEL+K F G SL L +KF + L L + L IHCDLKPENVLL RS IKV+DFGSSC ++R+Y YIQSRFYRAPEV+L Y M IDMWSLGCIL EL TG PL G+ E++Q+ IIE+ GMPP + +KRA + FI S+ A + V KR G A + S G DE F+D + R L DP R+TP +ALKH +
Sbjct: 133 RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSD---------GTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRL--IHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAKRA-RTFITSK-GYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMG-------DE---------LFVDFLKRCLDWDPETRMTPAQALKHKWL 447
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Celegans
Match: mbk-2 (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTF3]) HSP 1 Score: 243.047 bits (619), Expect = 7.664e-70 Identity = 146/344 (42.44%), Postives = 192/344 (55.81%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
RY + +IG GSFGQV++A D + VA+K++RN + F +QA+ EIR+L L + D G + I+ + +F +R H C+ FELL+ +LYEL+K F G SL L +KF + L L + L IHCDLKPENVLL RS IKV+DFGSSC ++R+Y YIQSRFYRAPEV+L Y M IDMWSLGCIL EL TG PL G+ E++Q+ IIE+ GMPP + +KRA + FI S+ A + V KR G A + S G DE F+D + R L DP R+TP +ALKH +
Sbjct: 133 RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSD---------GTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRL--IHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAKRA-RTFITSK-GYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMG-------DE---------LFVDFLKRCLDWDPETRMTPAQALKHKWL 447
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Celegans
Match: mbk-2 (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTF3]) HSP 1 Score: 243.047 bits (619), Expect = 1.108e-69 Identity = 146/344 (42.44%), Postives = 192/344 (55.81%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
RY + +IG GSFGQV++A D + VA+K++RN + F +QA+ EIR+L L + D G + I+ + +F +R H C+ FELL+ +LYEL+K F G SL L +KF + L L + L IHCDLKPENVLL RS IKV+DFGSSC ++R+Y YIQSRFYRAPEV+L Y M IDMWSLGCIL EL TG PL G+ E++Q+ IIE+ GMPP + +KRA + FI S+ A + V KR G A + S G DE F+D + R L DP R+TP +ALKH +
Sbjct: 133 RYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSD---------GTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRL--IHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAKRA-RTFITSK-GYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMG-------DE---------LFVDFLKRCLDWDPETRMTPAQALKHKWL 447
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Fly
Match: mnb (gene:FBgn0259168 transcript:FBtr0299619) HSP 1 Score: 385.956 bits (990), Expect = 1.105e-119 Identity = 192/356 (53.93%), Postives = 258/356 (72.47%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y++K GE +++RY +D LIG GSFGQVV+A D VAIKII+N++ F+ QA+ E++LL M+ + + IV+LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FLS P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL + Y++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV GMPP +++ + + K+F + + +++ + +N++G++ ++ G+RKL I+G ETGGP GRR DEPGHS DY F DLI RML DP R+TP AL+H FF
Sbjct: 151 DYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYY---------IVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKI------VADGSYV-----LKKNQNGRK--YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFF 484
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Fly
Match: mnb (gene:FBgn0259168 transcript:FBtr0300509) HSP 1 Score: 385.956 bits (990), Expect = 1.122e-119 Identity = 192/356 (53.93%), Postives = 258/356 (72.47%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y++K GE +++RY +D LIG GSFGQVV+A D VAIKII+N++ F+ QA+ E++LL M+ + + IV+LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FLS P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL + Y++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV GMPP +++ + + K+F + + +++ + +N++G++ ++ G+RKL I+G ETGGP GRR DEPGHS DY F DLI RML DP R+TP AL+H FF
Sbjct: 151 DYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYY---------IVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKI------VADGSYV-----LKKNQNGRK--YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFF 484
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Fly
Match: mnb (gene:FBgn0259168 transcript:FBtr0342786) HSP 1 Score: 385.571 bits (989), Expect = 6.982e-118 Identity = 192/356 (53.93%), Postives = 258/356 (72.47%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y++K GE +++RY +D LIG GSFGQVV+A D VAIKII+N++ F+ QA+ E++LL M+ + + IV+LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FLS P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL + Y++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV GMPP +++ + + K+F + + +++ + +N++G++ ++ G+RKL I+G ETGGP GRR DEPGHS DY F DLI RML DP R+TP AL+H FF
Sbjct: 290 DYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYY---------IVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKI------VADGSYV-----LKKNQNGRK--YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFF 623
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Fly
Match: mnb (gene:FBgn0259168 transcript:FBtr0300508) HSP 1 Score: 385.956 bits (990), Expect = 2.799e-116 Identity = 192/356 (53.93%), Postives = 258/356 (72.47%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y++K GE +++RY +D LIG GSFGQVV+A D VAIKII+N++ F+ QA+ E++LL M+ + + IV+LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FLS P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL + Y++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV GMPP +++ + + K+F + + +++ + +N++G++ ++ G+RKL I+G ETGGP GRR DEPGHS DY F DLI RML DP R+TP AL+H FF
Sbjct: 151 DYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYY---------IVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKI------VADGSYV-----LKKNQNGRK--YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFF 484
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Fly
Match: mnb (gene:FBgn0259168 transcript:FBtr0300510) HSP 1 Score: 385.185 bits (988), Expect = 8.955e-115 Identity = 192/356 (53.93%), Postives = 258/356 (72.47%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y++K GE +++RY +D LIG GSFGQVV+A D VAIKII+N++ F+ QA+ E++LL M+ + + IV+LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FLS P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL + Y++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV GMPP +++ + + K+F + + +++ + +N++G++ ++ G+RKL I+G ETGGP GRR DEPGHS DY F DLI RML DP R+TP AL+H FF
Sbjct: 290 DYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYY---------IVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIVEVLGMPPKYLLDQAHKTRKFFDKI------VADGSYV-----LKKNQNGRK--YKPPGSRKLHDILGVETGGPGGRRLDEPGHSVSDYLKFKDLILRMLDFDPKTRVTPYYALQHNFF 623
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Zebrafish
Match: dyrk1b (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B [Source:ZFIN;Acc:ZDB-GENE-060503-499]) HSP 1 Score: 394.045 bits (1011), Expect = 1.228e-121 Identity = 197/360 (54.72%), Postives = 254/360 (70.56%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGV------GARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+VK GE W++RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+HM+ + +A KYF + + V +N+D K++ + R+L I+G ETGGP GRR E GH+P DY F DLI RML DP RITP AL+H FF
Sbjct: 100 IVKNGEKWLDRYEIDSLIGKGSFGQVVKAYDHHEQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGVPPNHMLDQAPKARKYFDKLSDGLW------------TVKKNKDIKKVLYPSASEYKPPATRRLHEILGVETGGPGGRRAGEQGHAPCDYLKFKDLILRMLDYDPKTRITPFYALQHNFF 438
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Zebrafish
Match: dyrk1ab (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b [Source:ZFIN;Acc:ZDB-GENE-030131-5677]) HSP 1 Score: 395.201 bits (1014), Expect = 1.367e-121 Identity = 195/356 (54.78%), Postives = 256/356 (71.91%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G + + + +DGKR ++ +RKL +I+G E GGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 108 DYVVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGTWS-------IKKTKDGKR--YKPPASRKLHAILGVECGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 440
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Zebrafish
Match: dyrk1ab (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b [Source:ZFIN;Acc:ZDB-GENE-030131-5677]) HSP 1 Score: 395.201 bits (1014), Expect = 1.615e-121 Identity = 195/356 (54.78%), Postives = 256/356 (71.91%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G + + + +DGKR ++ +RKL +I+G E GGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 116 DYVVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGTWS-------IKKTKDGKR--YKPPASRKLHAILGVECGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 448
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Zebrafish
Match: dyrk1b (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B [Source:ZFIN;Acc:ZDB-GENE-060503-499]) HSP 1 Score: 394.045 bits (1011), Expect = 7.303e-121 Identity = 197/354 (55.65%), Postives = 254/354 (71.75%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+VK GE W++RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+HM+ + +A KYF + + V +N+D K+ ++ R+L I+G ETGGP GRR E GH+P DY F DLI RML DP RITP AL+H FF
Sbjct: 100 IVKNGEKWLDRYEIDSLIGKGSFGQVVKAYDHHEQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGVPPNHMLDQAPKARKYFDKLSDGLW------------TVKKNKDIKK-EYKPPATRRLHEILGVETGGPGGRRAGEQGHAPCDYLKFKDLILRMLDYDPKTRITPFYALQHNFF 431
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Zebrafish
Match: dyrk1aa (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a [Source:ZFIN;Acc:ZDB-GENE-050302-29]) HSP 1 Score: 382.104 bits (980), Expect = 1.127e-116 Identity = 197/356 (55.34%), Postives = 256/356 (71.91%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + M + + +DGKR ++ G+RKL SI+G E GGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 147 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGVPPSHILEQAPKARKFFEKMPDSMWCAK------------KTKDGKR--YKPAGSRKLHSILGVEAGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFF 479
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Xenopus
Match: gdf7 (growth differentiation factor 7 [Source:Xenbase;Acc:XB-GENE-484925]) HSP 1 Score: 398.667 bits (1023), Expect = 6.976e-125 Identity = 201/356 (56.46%), Postives = 257/356 (72.19%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G PP+HM+ + +A KYF ++ E V +N+D K+ ++ G R+L ++G ETGGP GRR E GHSP DY F DLI RML DP RITP AL+H FF
Sbjct: 73 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDHHDQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGTPPNHMLDQAPKARKYF----DKLPEGTWT--------VKKNKDLKK-DYKVPGTRRLHEVLGVETGGPGGRRAGEQGHSPSDYLKFKDLILRMLDYDPKTRITPFYALQHNFF 406
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Xenopus
Match: gdf7 (growth differentiation factor 7 [Source:Xenbase;Acc:XB-GENE-484925]) HSP 1 Score: 401.749 bits (1031), Expect = 1.444e-124 Identity = 201/356 (56.46%), Postives = 257/356 (72.19%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G PP+HM+ + +A KYF ++ E V +N+D K+ ++ G R+L ++G ETGGP GRR E GHSP DY F DLI RML DP RITP AL+H FF
Sbjct: 98 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDHHDQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGTPPNHMLDQAPKARKYF----DKLPEGTWT--------VKKNKDLKK-DYKVPGTRRLHEVLGVETGGPGGRRAGEQGHSPSDYLKFKDLILRMLDYDPKTRITPFYALQHNFF 431
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Xenopus
Match: gdf7 (growth differentiation factor 7 [Source:Xenbase;Acc:XB-GENE-484925]) HSP 1 Score: 400.979 bits (1029), Expect = 2.456e-124 Identity = 201/356 (56.46%), Postives = 257/356 (72.19%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G PP+HM+ + +A KYF ++ E V +N+D K+ ++ G R+L ++G ETGGP GRR E GHSP DY F DLI RML DP RITP AL+H FF
Sbjct: 87 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDHHDQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGTPPNHMLDQAPKARKYF----DKLPEGTWT--------VKKNKDLKK-DYKVPGTRRLHEVLGVETGGPGGRRAGEQGHSPSDYLKFKDLILRMLDYDPKTRITPFYALQHNFF 420
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Xenopus
Match: gdf7 (growth differentiation factor 7 [Source:Xenbase;Acc:XB-GENE-484925]) HSP 1 Score: 400.979 bits (1029), Expect = 2.430e-123 Identity = 201/356 (56.46%), Postives = 257/356 (72.19%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G PP+HM+ + +A KYF ++ E V +N+D K+ ++ G R+L ++G ETGGP GRR E GHSP DY F DLI RML DP RITP AL+H FF
Sbjct: 172 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDHHDQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGTPPNHMLDQAPKARKYF----DKLPEGTWT--------VKKNKDLKK-DYKVPGTRRLHEVLGVETGGPGGRRAGEQGHSPSDYLKFKDLILRMLDYDPKTRITPFYALQHNFF 505
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Xenopus
Match: osbpl8 (oxysterol binding protein like 8 [Source:Xenbase;Acc:XB-GENE-5961068]) HSP 1 Score: 375.17 bits (962), Expect = 1.098e-115 Identity = 197/371 (53.10%), Postives = 259/371 (69.81%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGK+ ++ G RKL +++G ETGGP GRR E GH+ DY F DLI RML D RI P AL+H FF T +S + TS
Sbjct: 147 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMSKIVEVLGIPPAHILDQAPKARKFF-----EKMPEGTWN-------LKKTKDGKK-EYKPPGTRKLHNLLGVETGGPGGRRGGESGHTVADYLKFKDLILRMLDYDAKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 495
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Mouse
Match: Dyrk1a (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a [Source:MGI Symbol;Acc:MGI:1330299]) HSP 1 Score: 398.282 bits (1022), Expect = 1.038e-122 Identity = 199/371 (53.64%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G + + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 110 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWS-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 458
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Mouse
Match: Dyrk1b (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b [Source:MGI Symbol;Acc:MGI:1330302]) HSP 1 Score: 394.43 bits (1012), Expect = 1.996e-122 Identity = 198/379 (52.24%), Postives = 257/379 (67.81%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
+Y+V+ GE W+ RY +D LIG GSFGQVV+A D T E VAIKII+N+++F+ QA+ E+RLL ++ ++ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT F GVSLNLT+K QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ RI+EV G+PP M+ + +A KYF + R R ++G G R+L ++G +TGGP GRR EPGHSP DY F DL+ RML +P RI+P AL+H FF +T + A +S SP+
Sbjct: 98 DYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYF-------------ERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAG-SSASTSPA 453
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Mouse
Match: Dyrk1a (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a [Source:MGI Symbol;Acc:MGI:1330299]) HSP 1 Score: 398.282 bits (1022), Expect = 3.205e-122 Identity = 199/371 (53.64%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G + + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWS-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Mouse
Match: Dyrk1a (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a [Source:MGI Symbol;Acc:MGI:1330299]) HSP 1 Score: 398.282 bits (1022), Expect = 3.205e-122 Identity = 199/371 (53.64%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G + + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWS-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Mouse
Match: Dyrk1b (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b [Source:MGI Symbol;Acc:MGI:1330302]) HSP 1 Score: 394.43 bits (1012), Expect = 1.282e-121 Identity = 198/379 (52.24%), Postives = 257/379 (67.81%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
+Y+V+ GE W+ RY +D LIG GSFGQVV+A D T E VAIKII+N+++F+ QA+ E+RLL ++ ++ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT F GVSLNLT+K QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ RI+EV G+PP M+ + +A KYF + R R ++G G R+L ++G +TGGP GRR EPGHSP DY F DL+ RML +P RI+P AL+H FF +T + A +S SP+
Sbjct: 158 DYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYF-------------ERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAG-SSASTSPA 513
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. UniProt/SwissProt
Match: sp|Q13627|DYR1A_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens OX=9606 GN=DYRK1A PE=1 SV=2) HSP 1 Score: 400.593 bits (1028), Expect = 2.784e-122 Identity = 200/371 (53.91%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G N + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWN-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. UniProt/SwissProt
Match: sp|Q9Z188|DYR1B_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Mus musculus OX=10090 GN=Dyrk1b PE=1 SV=3) HSP 1 Score: 394.43 bits (1012), Expect = 1.396e-121 Identity = 198/379 (52.24%), Postives = 257/379 (67.81%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
+Y+V+ GE W+ RY +D LIG GSFGQVV+A D T E VAIKII+N+++F+ QA+ E+RLL ++ ++ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT F GVSLNLT+K QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ RI+EV G+PP M+ + +A KYF + R R ++G G R+L ++G +TGGP GRR EPGHSP DY F DL+ RML +P RI+P AL+H FF +T + A +S SP+
Sbjct: 98 DYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYF-------------ERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAG-SSASTSPA 453
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. UniProt/SwissProt
Match: sp|Q63470|DYR1A_RAT (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Rattus norvegicus OX=10116 GN=Dyrk1a PE=1 SV=2) HSP 1 Score: 398.282 bits (1022), Expect = 1.982e-121 Identity = 199/371 (53.64%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G + + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWS-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. UniProt/SwissProt
Match: sp|Q61214|DYR1A_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Mus musculus OX=10090 GN=Dyrk1a PE=1 SV=1) HSP 1 Score: 398.282 bits (1022), Expect = 2.242e-121 Identity = 199/371 (53.64%), Postives = 261/371 (70.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTS 2575
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F + G + + + +DGKR ++ G RKL +I+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF T +S + TS
Sbjct: 148 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFF-----EKLPDGTWS-------LKKTKDGKR-EYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTS 496
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. UniProt/SwissProt
Match: sp|Q9Y463|DYR1B_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Homo sapiens OX=9606 GN=DYRK1B PE=1 SV=1) HSP 1 Score: 393.66 bits (1010), Expect = 2.731e-121 Identity = 198/379 (52.24%), Postives = 257/379 (67.81%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
+Y+V+ GE W+ RY +D LIG GSFGQVV+A D T E VAIKII+N+++F+ QA+ E+RLL ++ ++ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT F GVSLNLT+K QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ RI+EV G+PP M+ + +A KYF + R R ++G G R+L ++G +TGGP GRR EPGHSP DY F DL+ RML +P RI+P AL+H FF +T + A +S SP+
Sbjct: 98 DYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYF-------------ERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAG-SSASTSPA 453
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. TrEMBL
Match: A0A068WAP0 (Dual specificity OS=Echinococcus granulosus OX=6210 GN=EgrG_000987500 PE=4 SV=1) HSP 1 Score: 450.669 bits (1158), Expect = 1.939e-134 Identity = 222/380 (58.42%), Postives = 279/380 (73.42%), Query Frame = 2
Query: 1427 HCNTNSSTAK-EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTA 2563
H + N + A +Y+V+PGEVWMNRY MD LIG GSFGQV++A D + E VAIKII+N+R+F QA EIRLL + + Q+ + + GAN +VRL +HF++RGHLCLVFELL+++LY+LL+NT+F GVSLNLT+KF QLCSAL FLS+P LQIIHCDLKPEN+LL++PKRSAIK+VDFGSSC +NE++Y YIQSRFYR+P+VLL L Y MAIDMWSLGCILVELHTG+PLF GQ+E +Q+L+IIEV GM P ++I S+R +F E E N N + + +D +I ++ GARKLS I+G +GGP GRR EPGHSPQDYA F+DL+ ML DP KRI P EAL H FFC T + A
Sbjct: 634 HVDPNHTDANCDYIVRPGEVWMNRYYMDSLIGKGSFGQVMKARDFVANEDVAIKIIKNKRAFTNQAREEIRLLTQMNRLQDSNTDASNSNHGANYVVRLLTHFVFRGHLCLVFELLSHNLYDLLRNTNFRGVSLNLTRKFTQQLCSALEFLSRPDLQIIHCDLKPENILLINPKRSAIKLVDFGSSCHVNEKVYQYIQSRFYRSPDVLLGLDYTMAIDMWSLGCILVELHTGEPLFAGQHELDQMLKIIEVLGMLPSYLIEKSRRWPMFF-EREP------NGNFVPNYQASM--KDNVKINYKPPGARKLSDILGVNSGGPMGRRLQEPGHSPQDYAIFMDLVLHMLIYDPDKRIRPSEALAHRFFCRTAPQPTSRAIA 1004
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. TrEMBL
Match: A0A564YX26 (Protein kinase domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS10358 PE=4 SV=1) HSP 1 Score: 448.358 bits (1152), Expect = 8.666e-134 Identity = 227/397 (57.18%), Postives = 283/397 (71.28%), Query Frame = 2
Query: 1403 ACCVPKCSHCNTNSSTAK-EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQE-DQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNS 2587
A + H + N + A +Y+V+PGEVWMNRY MD LIG GSFGQV++A D + E VAIKII+N+R+F QA EIRLL + Q+ + + + GAN +VRL +HFM+RGHLCLVFELL+++LY+LL+NT+F GVSLNLT+KF QLCSAL FLS+P LQIIHCDLKPEN+LL++PKRSAIK+VDFGSSC +NE++Y YIQSRFYR+P+VLL L Y MAIDMWSLGCILVELHTG+PLF GQ+E +Q+L+IIEV GM P ++I S+R F E E N N +D I ++ G RKL+ I+G +GGP GRR EPGHSPQDYA F+DL+ +MLT DP KRI P EAL H FFC R +T T T +R S
Sbjct: 633 AAATDQQHHVDPNYTDANYDYIVRPGEVWMNRYYMDSLIGKGSFGQVMKARDFVANEDVAIKIIKNKRAFTNQAREEIRLLTKMNHLQDLNAADGSNSNQGANYVVRLLTHFMFRGHLCLVFELLSHNLYDLLRNTNFRGVSLNLTRKFTQQLCSALEFLSRPDLQIIHCDLKPENILLINPKRSAIKLVDFGSSCHVNEKVYQYIQSRFYRSPDVLLGLDYTMAIDMWSLGCILVELHTGEPLFAGQHELDQMLKIIEVLGMLPSYLIEKSRRW-PLFFEREPGGNFVPNYKA--------SMKDNIPISYKAPGTRKLNDILGVNSGGPMGRRLQEPGHSPQDYAIFMDLVLQMLTYDPEKRIRPSEALAHRFFC---RTNTAVPTHPQTVLRQS 1017
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. TrEMBL
Match: A0A068YFR1 (Dual specificity OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000987500 PE=4 SV=1) HSP 1 Score: 447.973 bits (1151), Expect = 1.295e-133 Identity = 221/380 (58.16%), Postives = 279/380 (73.42%), Query Frame = 2
Query: 1427 HCNTNSSTAK-EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTA 2563
H + N + A +Y+V+PGEVWMNRY MD LIG GSFGQV++A D + E VAIKII+N+R+F QA EIRLL + + Q+ + + GAN +VRL +HF++RGHLCLVFELL+++LY+LL+NT+F GVSLNLT+KF QLCSAL FLS+P LQIIHCDLKPEN+LL++PKRSAIK+VDFGSSC +NE++Y YIQSRFYR+P+VLL L Y MAIDMWSLGCILVELHTG+PLF GQ+E +Q+L+IIEV GM P ++I S+R +F E + N N+ + +D +I ++ GARKLS I+G +GGP GRR EPGHSPQDYA F+DL+ ML DP KRI P EAL H FFC T + A
Sbjct: 622 HVDPNHTDANCDYIVRPGEVWMNRYYMDSLIGKGSFGQVMKARDFVANEDVAIKIIKNKRAFTNQAREEIRLLTQMNRLQDSNTDASNCNHGANYVVRLLTHFVFRGHLCLVFELLSHNLYDLLRNTNFRGVSLNLTRKFTQQLCSALEFLSRPDLQIIHCDLKPENILLINPKRSAIKLVDFGSSCHVNEKVYQYIQSRFYRSPDVLLGLDYTMAIDMWSLGCILVELHTGEPLFAGQHELDQMLKIIEVLGMLPSYLIEKSRRWPMFF---EREPNGDFVPNYQASM------KDNVKINYKPPGARKLSDILGVNSGGPMGRRLQEPGHSPQDYAIFMDLVLHMLIYDPDKRIRPSEALAHRFFCRTAPQPTSRAIA 992
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. TrEMBL
Match: A0A3P7VDD6 (Protein kinase domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS7758 PE=4 SV=1) HSP 1 Score: 421.009 bits (1081), Expect = 1.188e-129 Identity = 226/431 (52.44%), Postives = 280/431 (64.97%), Query Frame = 2
Query: 1427 HCNTNSSTAK-EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQE---------DQDVVTV------PH----------------------------WGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNS 2587
H + N + A +Y+V+ GEVWMNRY MD LIG GSFGQV++A D + VAIKII+N+R+F QA EIRLL + QE +Q V PH + C+VRL +HFM+RGHLCLVFELL+++LY+LL+NT+F GVSLNLT+KF QLCSAL FLS+P LQIIHCDLKPEN+LL++PKRSAIK+VDFGSSC +NE++Y YIQSRFYR+P+VLL L Y MAIDMWSLGCILVELHTG+PLF GQ+E +Q+L+IIEV GM P ++I S+R +F E E N N +D I ++ G RKL+ I+G +GGP GRR EPGHSP DYA F+DL+ +MLT DP KRI P EAL H FFC R +T T T +R S
Sbjct: 144 HVDPNYTDANYDYIVRSGEVWMNRYYMDSLIGKGSFGQVMKARDFVANADVAIKIIKNKRAFTNQAREEIRLLTKMNHLQEFNAADGSNSNQGANYVVMCALCPHIPIVAVARSFLPISVSYNAASTYSFSLIFSLPCVVRLLTHFMFRGHLCLVFELLSHNLYDLLRNTNFRGVSLNLTRKFTQQLCSALEFLSRPDLQIIHCDLKPENILLINPKRSAIKLVDFGSSCHVNEKVYQYIQSRFYRSPDVLLGLDYTMAIDMWSLGCILVELHTGEPLFAGQHELDQMLKIIEVLGMLPSYLIEKSRRWPLFF-EREPGGNFVPNYKS--------SMKDNIPISYKAPGTRKLNDILGVNSGGPMGRRLQEPGHSPHDYAIFMDLVLQMLTYDPEKRIRPSEALAHRFFC---RTTTAVPTHPQTVLRQS 562
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. TrEMBL
Match: A0A158QHP4 (Protein kinase domain-containing protein OS=Rodentolepis nana OX=102285 PE=4 SV=1) HSP 1 Score: 421.009 bits (1081), Expect = 1.201e-129 Identity = 226/431 (52.44%), Postives = 280/431 (64.97%), Query Frame = 2
Query: 1427 HCNTNSSTAK-EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQE---------DQDVVTV------PH----------------------------WGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNS 2587
H + N + A +Y+V+ GEVWMNRY MD LIG GSFGQV++A D + VAIKII+N+R+F QA EIRLL + QE +Q V PH + C+VRL +HFM+RGHLCLVFELL+++LY+LL+NT+F GVSLNLT+KF QLCSAL FLS+P LQIIHCDLKPEN+LL++PKRSAIK+VDFGSSC +NE++Y YIQSRFYR+P+VLL L Y MAIDMWSLGCILVELHTG+PLF GQ+E +Q+L+IIEV GM P ++I S+R +F E E N N +D I ++ G RKL+ I+G +GGP GRR EPGHSP DYA F+DL+ +MLT DP KRI P EAL H FFC R +T T T +R S
Sbjct: 144 HVDPNYTDANYDYIVRSGEVWMNRYYMDSLIGKGSFGQVMKARDFVANADVAIKIIKNKRAFTNQAREEIRLLTKMNHLQEFNAADGSNSNQGANYVVMCALCPHIPIVAVARSFLPISVSYNAASTYSFSLIFSLPCVVRLLTHFMFRGHLCLVFELLSHNLYDLLRNTNFRGVSLNLTRKFTQQLCSALEFLSRPDLQIIHCDLKPENILLINPKRSAIKLVDFGSSCHVNEKVYQYIQSRFYRSPDVLLGLDYTMAIDMWSLGCILVELHTGEPLFAGQHELDQMLKIIEVLGMLPSYLIEKSRRWPLFF-EREPGGNFVPNYKS--------SMKDNIPISYKAPGTRKLNDILGVNSGGPMGRRLQEPGHSPHDYAIFMDLVLQMLTYDPEKRIRPSEALAHRFFC---RTTTAVPTHPQTVLRQS 562
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Cavefish
Match: dyrk1aa (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a [Source:ZFIN;Acc:ZDB-GENE-050302-29]) HSP 1 Score: 377.867 bits (969), Expect = 4.933e-115 Identity = 197/356 (55.34%), Postives = 256/356 (71.91%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP H++ + +A K+F E + + A + +DGKR ++ G+RKL +I+G E GGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 129 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRHEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGVPPSHILDQAPKARKFF---EKMSDSTWCAK---------KTKDGKR--YKPAGSRKLHNILGVEAGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKSRIQPYYALQHSFF 461
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Cavefish
Match: dyrk1ab (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b [Source:ZFIN;Acc:ZDB-GENE-030131-5677]) HSP 1 Score: 378.252 bits (970), Expect = 5.062e-115 Identity = 195/356 (54.78%), Postives = 257/356 (72.19%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+Y+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G+ + V + +DGKR ++ +RKL +I+G E GGP GRR E GH+ DY F DL+ RML DP RI P AL+H FF
Sbjct: 142 DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGSWS-------VKKTKDGKR--YKPPASRKLHAILGVEAGGPGGRRAGESGHAVADYLKFKDLVLRMLDYDPKTRIQPYYALQHSFF 474
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Cavefish
Match: dyrk4 (dual specificity tyrosine phosphorylation regulated kinase 4 [Source:NCBI gene;Acc:103029392]) HSP 1 Score: 261.536 bits (667), Expect = 1.940e-74 Identity = 149/353 (42.21%), Postives = 210/353 (59.49%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTL 2551
RY + +IG GSFGQV++ D T E VAIKIIRN++ F QQA E+++L + + D + ++ +K +F +R HLC+ FELL +LYEL+K +F G SL L ++F L L L + +IIHCDLKPEN+LL + IKVVDFGSSC +R+Y YIQSRFYR+PEV+L PY+MAIDMWSLGCIL EL+TG PLF G+ E EQI I+EV GMPP+ ++ + R +F + GN ++++ ++ KR P +++L+S++ T ++P FLD I R L DP KR+TP+E ++H + GR + L
Sbjct: 206 RYEVLEVIGKGSFGQVLKCLDHKTNEMVAIKIIRNKKRFHQQALVELKILDAVRRKDRD---------SCHNVIHMKEYFYFRNHLCISFELLGANLYELIKKNNFQGFSLALIRRFAHSLLKCLQMLHRE--KIIHCDLKPENILLSQRGQGNIKVVDFGSSCYEQQRVYTYIQSRFYRSPEVILGHPYSMAIDMWSLGCILAELYTGYPLFPGESEVEQIACIMEVMGMPPNDFVQTASRRRLFF-------DSKGNPRNVTN------SKGKKRRP----NSKELASVLKT----------NDP--------LFLDFIRRCLVWDPTKRMTPDEGMQHEWI-TEGRLTRL 511
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Cavefish
Match: dyrk4 (dual specificity tyrosine phosphorylation regulated kinase 4 [Source:NCBI gene;Acc:103029392]) HSP 1 Score: 261.536 bits (667), Expect = 2.008e-74 Identity = 149/353 (42.21%), Postives = 210/353 (59.49%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTL 2551
RY + +IG GSFGQV++ D T E VAIKIIRN++ F QQA E+++L + + D + ++ +K +F +R HLC+ FELL +LYEL+K +F G SL L ++F L L L + +IIHCDLKPEN+LL + IKVVDFGSSC +R+Y YIQSRFYR+PEV+L PY+MAIDMWSLGCIL EL+TG PLF G+ E EQI I+EV GMPP+ ++ + R +F + GN ++++ ++ KR P +++L+S++ T ++P FLD I R L DP KR+TP+E ++H + GR + L
Sbjct: 198 RYEVLEVIGKGSFGQVLKCLDHKTNEMVAIKIIRNKKRFHQQALVELKILDAVRRKDRD---------SCHNVIHMKEYFYFRNHLCISFELLGANLYELIKKNNFQGFSLALIRRFAHSLLKCLQMLHRE--KIIHCDLKPENILLSQRGQGNIKVVDFGSSCYEQQRVYTYIQSRFYRSPEVILGHPYSMAIDMWSLGCILAELYTGYPLFPGESEVEQIACIMEVMGMPPNDFVQTASRRRLFF-------DSKGNPRNVTN------SKGKKRRP----NSKELASVLKT----------NDP--------LFLDFIRRCLVWDPTKRMTPDEGMQHEWI-TEGRLTRL 503
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Cavefish
Match: dyrk4 (dual specificity tyrosine phosphorylation regulated kinase 4 [Source:NCBI gene;Acc:103029392]) HSP 1 Score: 261.151 bits (666), Expect = 2.277e-74 Identity = 149/353 (42.21%), Postives = 210/353 (59.49%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTL 2551
RY + +IG GSFGQV++ D T E VAIKIIRN++ F QQA E+++L + + D + ++ +K +F +R HLC+ FELL +LYEL+K +F G SL L ++F L L L + +IIHCDLKPEN+LL + IKVVDFGSSC +R+Y YIQSRFYR+PEV+L PY+MAIDMWSLGCIL EL+TG PLF G+ E EQI I+EV GMPP+ ++ + R +F + GN ++++ ++ KR P +++L+S++ T ++P FLD I R L DP KR+TP+E ++H + GR + L
Sbjct: 195 RYEVLEVIGKGSFGQVLKCLDHKTNEMVAIKIIRNKKRFHQQALVELKILDAVRRKDRD---------SCHNVIHMKEYFYFRNHLCISFELLGANLYELIKKNNFQGFSLALIRRFAHSLLKCLQMLHRE--KIIHCDLKPENILLSQRGQGNIKVVDFGSSCYEQQRVYTYIQSRFYRSPEVILGHPYSMAIDMWSLGCILAELYTGYPLFPGESEVEQIACIMEVMGMPPNDFVQTASRRRLFF-------DSKGNPRNVTN------SKGKKRRP----NSKELASVLKT----------NDP--------LFLDFIRRCLVWDPTKRMTPDEGMQHEWI-TEGRLTRL 500
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Sea Lamprey
Match: dyrk1aa (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a [Source:ZFIN;Acc:ZDB-GENE-050302-29]) HSP 1 Score: 403.675 bits (1036), Expect = 9.223e-125 Identity = 205/377 (54.38%), Postives = 263/377 (69.76%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
+VK GE WM+RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ D IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP HM+ + +A KYF + G+ V + +D KR ++ G+RKL IIG E+GGP GRR E GH+ DY F DLI RML DP RITP AL+H FF + +T T S+ SP+
Sbjct: 151 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDHQEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTDMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGLPPTHMLEQAPKARKYF-----ERLSDGSWT-------VKKTKDSKR-EYKTAGSRKLHDIIGVESGGPGGRRMGEAGHTVADYLKFKDLILRMLDYDPKTRITPFYALQHNFF----KKTTDEGTNTSNSVSTSPA 501
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Sea Lamprey
Match: dyrk2 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2804]) HSP 1 Score: 243.047 bits (619), Expect = 2.111e-69 Identity = 145/349 (41.55%), Postives = 198/349 (56.73%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEP------KVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPF 2521
RY + +IG GSFGQVV+A D T VA+K++RN + F +QA EIR+L L K + + I+ L F +RGH+C+ FELL+ +LYEL+K F G SL L +KF + L L + +IIHCDLKPEN+LL P RS IKV+DFGSSC ++R+Y YIQSRFYRAPEV+L Y IDMWSLGCIL EL TG PL G+ E +Q+ +E+ GMPP ++ KR+ + F+ S G ++ P R+R GK P G+R+L + + R D+P LD + L +P +R+TP +AL+HP+
Sbjct: 161 RYEVLKVIGKGSFGQVVKAFDHKTQTHVALKMVRNEKRFHRQAAEEIRILEHLRKQDRENSM---------NIIHLLESFTFRGHVCMTFELLSMNLYELIKKNKFQGFSLALVRKFAHSILQCLDTLHRN--RIIHCDLKPENILLKQPGRSGIKVIDFGSSCFEHQRVYTYIQSRFYRAPEVVLGARYGPPIDMWSLGCILAELLTGSPLLPGEDEGDQLACAMELLGMPPQRLLAQGKRS-RNFVSSRGHPRYCG----VTEAPDGAVVLNAGRSRRGK--PRGPPGSRELPAAL---------RGCDDP--------LLLDFLRGCLEWEPSERLTPAQALRHPW 474
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Sea Lamprey
Match: dyrk2 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2804]) HSP 1 Score: 224.557 bits (571), Expect = 3.926e-63 Identity = 141/359 (39.28%), Postives = 194/359 (54.04%), Query Frame = 2
Query: 1460 YLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVV-DFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVF---RNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
Y+ P + RY + +IG GSFGQVV+A D T + VA+K++RN + F +QA EIR+L L K Q+ ++ + V H + F +R H+C+ FELL+ +LYEL+K F G SL + +KF + L+ L + +IIHCDLKPEN+LL RS IK++ DFGSSC ++R+Y YIQSRFYRAP Y + IDMWSLGCIL EL TG PL G+ E +Q+ +E+ G PP ++ SKRA ++F S + + P V R R GK GP R D F+D + + L DP R+TP +ALKHP+
Sbjct: 160 YIHVPHDHVAYRYEVLRVIGKGSFGQVVKAYDHRTHQYVALKMVRNEKRFHRQAAEEIRILEHLKK-QDKENTMNVIH--------MLESFNFRNHICMTFELLSMNLYELIKKNKFQGFSLQVVRKFAHSILLCLNALHKN--RIIHCDLKPENILLRQQGRSGIKIIIDFGSSCYEHQRVYTYIQSRFYRAPGGR----YGLPIDMWSLGCILAELLTGSPLLPGEDEGDQLACAMELTGSPPARLLEQSKRARQFF--SSLGHPRYCTVTTLPGGPVVLNGGRTRRGK-------------------LRGPPSSRDWTTALKGCDDHLFIDFLKKCLDWDPATRLTPSQALKHPWL 482
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Sea Lamprey
Match: hipk2 (homeodomain interacting protein kinase 2 [Source:ZFIN;Acc:ZDB-GENE-031125-4]) HSP 1 Score: 204.912 bits (520), Expect = 7.018e-54 Identity = 126/359 (35.10%), Postives = 193/359 (53.76%), Query Frame = 2
Query: 1490 NRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSA--IKVVDFGSSCRLNERL-YVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHI-------SHEPKV-FRNRDGKRIPF---EGVG-ARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPF 2521
N Y + +G G+FGQVV+ T E VAIKI++N S+ +Q + E+ +L L+ D VR F ++ H CLVFE+L +LY+ LK +FS + L + Q+ SAL L SL +IH DLKPEN++LV P R +KV+DFGS+ +++ + Y+QSR+YRAPE++L LP+ AIDMWSLGC++ EL G PL+ G E++QI I G+PP+ ++ + ++F E+G + HE + ++++ ++ F E +G S + G++ R+ F++L+ RMLT+D KRI+P E L HPF
Sbjct: 190 NSYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQVEVGILARLSSESADD----------YNFVRAHECFQHKSHTCLVFEMLEQNLYDFLKQNNFSPLPLKYIRPVLQQVASALMKLK--SLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISATQGLPPEQLLSAGTKTGRFF------QRETGAGYPLWRIKSPEEHEAETGIKSKEARKYMFNCLEDMGQVNPASDLEGSDVLAEKADRRQ-----------FIELLRRMLTMDADKRISPLETLAHPF 519
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007952.1 (pep scaffold:Pmarinus_7.0:GL476685:157428:173166:-1 gene:ENSPMAG00000007188.1 transcript:ENSPMAT00000007952.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 170.629 bits (431), Expect = 3.530e-47 Identity = 120/352 (34.09%), Postives = 171/352 (48.58%), Query Frame = 2
Query: 1478 EVW----MNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPF 2521
+VW + RY + ++G GSFG+V++ D + E VAIK++ R EI +L+ L +E ++ I+R+ HF +RG C+VFELL +L LK T G L + + F + L +L L + +IH DLKP N+ + + +K+ DFG SC +E + IQ+R YRAPEV+L L Y+ DMWSLGC L ELH+GQ LF G +Q+ I+EV G+PP MI S+ +F + N V NR R+P G+R L + R DE F D I L DP R+TP A+ H +
Sbjct: 1 KVWHEHLLYRYEVLEVLGQGSFGKVLKCLDHKSKEFVAIKVLNRARFNESVHRREIEILKRLQTARE-----------SSKIIRMMEHFSFRGRECVVFELLNGNLRSQLKLTHRQGFGLEMVRLFAISLLKSLEQLRDAN--VIHGDLKPGNIGICSYEAGEVKLFDFGCSCFDHEEHFTKIQTRHYRAPEVILDLGYSFPADMWSLGCTLAELHSGQKLFPGHTNEDQLHSIMEVFGLPPQDMIEESRVQLGFFACKDFSSN-------------VRLNRGLVRVP----GSRALPLAL---------RTTDEH---------FTDFIRSCLQWDPEWRLTPHGAMDHEW 304
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Yeast
Match: YAK1 (Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]) HSP 1 Score: 234.572 bits (597), Expect = 8.161e-65 Identity = 129/340 (37.94%), Postives = 197/340 (57.94%), Query Frame = 2
Query: 1511 LIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVF-RNRDGKRIPFEG-VGARKLSSIIGTETGGPDGRRKDE-PGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPF 2521
++G G+FGQVV+ +L+T E +A+K++++R ++ Q+ TE ++L +L + D H+ +R+ F+++ HLCLVFELL+ +LYELLK F G+S+ L + F Q+ +L L + L IHCDLKPEN+LL P + +K++DFGSSC +Y YIQSRFYRAPE++L +PY+ +IDMWSLGCI+ EL G P+F G E+ Q+ RII+ G PP MI K + K+ + + + S H + F R + P + RKL II + E Q+ C + + +L ++P +R TP++A+ HPF
Sbjct: 374 ILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELL---NQKIDPTNKHHF-----LRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKL--IHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPF 703
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Yeast
Match: KSS1 (Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]) HSP 1 Score: 124.02 bits (310), Expect = 7.623e-31 Identity = 114/364 (31.32%), Postives = 177/364 (48.63%), Query Frame = 2
Query: 1490 NRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIR--NRRSFVQQAETEIRLLRMLAKYQEDQDVVTV-PHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELL--KNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFG------SSCRLNERLY----VYIQSRFYRAPEVLL-YLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPP--DHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFC 2527
++Y + LIG G++G V A +G VAIK I+ +++ FV + EI+LLR + E ++++++ I +L + + LV EL+ L +++ +N+ FS +S + + F Q+ AL S S Q+IH D+KP N+LL +KV DFG SS E L Y+ +R+YRAPE++L + Y A+D+WS GCIL E+ +G+PLF G+ H Q+ I+EV G P D SKRA +Y AN P +P+E V ++ PD +DL+++ML +P KRI+ EAL+HP+
Sbjct: 11 SQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRY---FHEHENIISILDKVRPVSIDKLNAVY-------LVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALK--SIHSAQVIHRDIKPSNLLL--NSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYI------------ANLPMRPP----------LPWETVWSKT--------DLNPD----------------MIDLLDKMLQFNPDKRISAAEALRHPYLA 314
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 114.39 bits (285), Expect = 3.774e-27 Identity = 100/352 (28.41%), Postives = 156/352 (44.32%), Query Frame = 2
Query: 1490 NRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQED-----QDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLL-YLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIR--CSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPF 2521
NRY+ +G G+FG V A D +T +PVAIK I S A+ R L++L + + QD+ P + V EL L+ LL+ + F Q+ L ++ S +IH DLKP N+L+ + +K+ DFG + + ++ Y+ +R+YRAPE++L + Y++ +D+WS GCI E+ G+PLF G+ Q I ++ G PP +I CS+ K F+ S +RD IPF + + ++ PD +DL+ +ML DP KRIT +AL HP+
Sbjct: 21 NRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSP----------------LEDIYFVTELQGTDLHRLLQTRPLEK---QFVQYFLYQILRGLKYVH--SAGVIHRDLKPSNILI--NENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLK-FVTS-------------------LPHRD--PIPF----SERFKTV------EPDA----------------VDLLEKMLVFDPKKRITAADALAHPY 301
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 107.842 bits (268), Expect = 7.283e-26 Identity = 95/354 (26.84%), Postives = 158/354 (44.63%), Query Frame = 2
Query: 1514 IGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFS----GVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVY---IQSRFYRAPEVLL-YLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGP-DGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHST 2548
+G G++ V + + TG VA+K ++ S T IR + ++ + + + IVRL L LVFE + L + + + + G+ LNL K F QL L F + +I+H DLKP+N+L+ KR +K+ DFG + + + + + +YRAP+VL+ Y+ +ID+WS GCIL E+ TG+PLF G + EQ+ I ++ G P + + + KY N N I P R L ++ T P DG +D ++ +L ++P R++ ++AL HP+F H++
Sbjct: 13 LGNGTYATVYKGLNKTTGVYVALKEVK-LDSEEGTPSTAIREISLMKELKHEN------------IVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHEN--KILHRDLKPQNLLI--NKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKY------------NPN-IQQRP-----------------PRDLRQVLQPHTKEPLDGN--------------LMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS 305
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Yeast
Match: SLT2 (Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]) HSP 1 Score: 106.686 bits (265), Expect = 1.846e-24 Identity = 104/366 (28.42%), Postives = 161/366 (43.99%), Query Frame = 2
Query: 1493 RYSMDLLIGTGSFGQVVRANDLITGE--PVAIKIIRNRRS---FVQQAETEIRLLRMLAKYQE-----DQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLT--KKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNER-------LYVYIQSRFYRAPEVLL-YLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIR--CSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
R+ + IG G++G V A E VAIK + N S +++ E++LLR ++ D D+V P N + ++Y EL+ +++++K SG L + F Q+ L ++ S ++H DLKP N+L+ +K+ DFG + +E L Y+ +R+YRAPE++L Y Y AID+WS GCIL E G+P+F G+ Q+ +I++V G PPD +R SK Y + + PKV PF + P + LDL+ +ML DP KRIT +EAL+HP+
Sbjct: 22 RFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGL------YLYE-------ELMECDMHQIIK----SGQPLTDAHYQSFTYQILCGLKYIH--SADVLHRDLKPGNLLV--NADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYI-------------HQLGFIPKV---------PFVNL--------------------------YPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL 318
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Nematostella
Match: EDO45187 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC8]) HSP 1 Score: 382.104 bits (980), Expect = 7.858e-121 Identity = 196/379 (51.72%), Postives = 259/379 (68.34%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
+Y+VK GE W +RY ++ LIG GSFGQV +A D E +A+KII+N++ F+ QA+ E++LL ++ K D G IVRLK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF Q+C+AL FL P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC++ +R+Y YIQSRFYR+PEVLL +PYN+AIDMWSLGCILVE+HTG+PLF G E +Q+++I+EV GMPP ++ + +A K+F + + ++ + + +DG + + G+RKL I+G ETGGP GRR E GH+ QDY F DLI RML D RI P AL H FF + + T S NSP+
Sbjct: 66 DYIVKAGEKWFDRYEIESLIGKGSFGQVCKAYDHQEKEHIAVKIIKNKKPFLNQAQIEVKLLELMNKNDPD---------GKYYIVRLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLCSPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQIGQRIYQYIQSRFYRSPEVLLGIPYNLAIDMWSLGCILVEMHTGEPLFSGANEFDQMMKIVEVLGMPPKDILDNAPKARKFF-------DRLPDGSY-----QCLKVKDGVK-EYLSPGSRKLHDILGCETGGPGGRRLGEAGHTLQDYLKFKDLILRMLDYDRKTRIVPYAALHHCFF----KKTAEEGTNTTHSATNSPA 418
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Nematostella
Match: EDO46144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQP1]) HSP 1 Score: 248.44 bits (633), Expect = 3.396e-71 Identity = 150/360 (41.67%), Postives = 203/360 (56.39%), Query Frame = 2
Query: 1460 YLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFG---LQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANH--ISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
Y+ P + RY + +IG GSFGQVV+A D T VA+K++RN + F +QA+ EIR+L L K +D + I+ + HF +R H+C+ FELL+ +LYEL+K F G SL L +KF LQ ALH +IIHCDLKPEN+LL RS IKV+DFGSSC ++R+Y YIQSRFYRAPEV+L Y M IDMWS GCIL EL TG PLF G+ E +Q+ +E+ G P+ + SKRA + +N G + I+ P DG + G +R+ G G P+ + + D A F+D + R L DP R+TP +AL+HP+
Sbjct: 155 YIHVPKDHIAYRYEVLKIIGKGSFGQVVKALDHKTNTHVALKMVRNEKRFHRQAQEEIRILEHLKKQDKDN---------THNIIHMLEHFTFRNHVCMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALH-----KNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRIYTYIQSRFYRAPEVILGARYGMPIDMWSFGCILAELLTGYPLFPGEDEGDQLACNMELLGYIPEKLRETSKRAKNF-------INSKGYPRYCTITTLP------DGS-VAVSGGRSRR-----GKTRGAPNSKTFVQALKGCDD-AMFIDFLKRCLEWDPSARMTPSQALRHPWL 480
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Nematostella
Match: EDO36294 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ45]) HSP 1 Score: 240.35 bits (612), Expect = 6.652e-71 Identity = 125/274 (45.62%), Postives = 172/274 (62.77%), Query Frame = 2
Query: 1412 VPKCSHCNTNSSTAKEYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYF 2233
VP N YL + RY + ++G GSFGQVV+A D TG+ VA+KIIRN++ F QQA E+++L L K +D + ++ + HF +R HLC+ FEL+ +LYEL+K +F G SL L ++F L L + + +IIHCDLKPEN+LL +++IKV+DFGSSC ++R+Y YIQSRFYR+PEV+L LPY+MAIDMWS GCIL EL+TG PLF G+ E EQ+ I+EV G+P +I + R +F
Sbjct: 32 VPGAPQNNNYDDDNGSYLKALHDHLAYRYEVLEVLGKGSFGQVVKALDHKTGQHVAVKIIRNKKRFHQQALVEVKILDNLRKKDKDN---------THNLIHMIEHFYFRNHLCITFELMGMNLYELIKKNNFQGFSLALIRRFAFALLHCLKVIHKE--KIIHCDLKPENILLRQRGQTSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSFGCILAELYTGYPLFPGENEVEQLACIMEVLGLPSPKLIESASRRRLFF 294
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Nematostella
Match: EDO49238 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGV4]) HSP 1 Score: 202.216 bits (513), Expect = 2.600e-57 Identity = 128/366 (34.97%), Postives = 200/366 (54.64%), Query Frame = 2
Query: 1511 LIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSA--IKVVDFGSSCRLNERL-YVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYF-----IESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRN 2584
+G G+FGQVV+ T E VAIKI+++ S+ +Q + EI +L L+ + A VR F ++ H CLVFE+L +LY+ LK + F+ + L + Q+ AL L +L +IH DLKPEN++LV P + +KV+DFGS+ +++ + Y+QSR+YRAPEV+L LP+ +IDMWSLGC++ EL G PL+ G E +QI II+ G+P DH++ + + +++F + + + NAN E K+ +++ ++ F + ++ + TG +E D F+ L+ RMLTID KRITPEEAL H F + S +S++N
Sbjct: 4 FLGRGTFGQVVKCWKKGTNELVAIKILKDHPSYARQGQIEISILAKLSAENSE----------AYNFVRAIECFQHKNHTCLVFEMLQQNLYDYLKQSKFNPLPLKHIRPIVQQVLVALSKLR--TLGLIHADLKPENIMLVDPDKQPFRVKVIDFGSATHVSKVVCSTYLQSRYYRAPEVILGLPFCESIDMWSLGCVIAELFLGWPLYPGSSEFDQIRYIIQTQGLPYDHLLNNATKTSRFFKKAINTHTGVLEWKLKNANEHERETKI-PSKEARKYIFNSLDDIAQVNLSSSLTG-------NERIAEKIDRYEFVSLLKRMLTIDQEKRITPEEALSHQFVTLSHLVDFAHSNVFKSSVKN 349
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Nematostella
Match: EDO33758 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR83]) HSP 1 Score: 170.244 bits (430), Expect = 2.459e-45 Identity = 106/379 (27.97%), Postives = 187/379 (49.34%), Query Frame = 2
Query: 1475 GEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHP-----------------KRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFC-----CAGRHS 2545
G+ +RY + L+G G+FG+V+ D TG+ VA+K+I+N + + A+ EI++L + + +G + +++ F + GH+CLVFE + S+++ +K+ ++ L+ + QL A+ FL + +++ H DLKPEN+L V+ K S ++++DFGS+ +E + +R YRAPEV+L L ++ D+WS+GCI+ EL+TG LF E + + + G P + S R KYF + +++ +E ++ E + L + +++ G + F +L++ +L DP KRIT +EA++HPFF C RHS
Sbjct: 118 GDQLHSRYEVHCLLGEGTFGKVLECYDKKTGDVVAVKVIKNIEKYREAAKLEIKVLEKINQKNR---------YGKSLCIKMLDWFNHHGHMCLVFEKMGLSVFDFMKDNNYEPYPLDQVRHISYQLIVAVKFLHE--MKLTHTDLKPENMLFVNSDCDVFYNKDTKQDQRYVKSSHMRLIDFGSATFEHEHHSTTVSTRHYRAPEVILELGWSYPCDIWSIGCIMFELYTGFTLFQTHENREHLAMMERIIGPIPSDFAKKS-RKTKYFYKGKLEWDEKSSSGKYVRE-----------------NCKPLKKYMLSDSEG---------------HQLFFNLLDYLLEYDPEKRITAKEAMQHPFFNSMYYDCEMRHS 452
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Medaka
Match: dyrk1ab (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:NCBI gene;Acc:101169628]) HSP 1 Score: 398.282 bits (1022), Expect = 1.472e-122 Identity = 197/354 (55.65%), Postives = 256/354 (72.32%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G + V + +DGKR ++ +RKL SI+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 136 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGTWS-------VKKTKDGKR--YKPPASRKLHSILGVETGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKSRIQPYYALQHSFF 466
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Medaka
Match: dyrk1ab (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:NCBI gene;Acc:101169628]) HSP 1 Score: 397.127 bits (1019), Expect = 1.597e-122 Identity = 197/354 (55.65%), Postives = 256/354 (72.32%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G + V + +DGKR ++ +RKL SI+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 110 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGTWS-------VKKTKDGKR--YKPPASRKLHSILGVETGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKSRIQPYYALQHSFF 440
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Medaka
Match: dyrk1ab (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:NCBI gene;Acc:101169628]) HSP 1 Score: 397.512 bits (1020), Expect = 2.897e-122 Identity = 197/354 (55.65%), Postives = 256/354 (72.32%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G + V + +DGKR ++ +RKL SI+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 139 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGTWS-------VKKTKDGKR--YKPPASRKLHSILGVETGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKSRIQPYYALQHSFF 469
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Medaka
Match: dyrk1ab (dual specificity tyrosine phosphorylation regulated kinase 1A [Source:NCBI gene;Acc:101169628]) HSP 1 Score: 397.512 bits (1020), Expect = 2.897e-122 Identity = 197/354 (55.65%), Postives = 256/354 (72.32%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
+VK GE WM+RY +D LIG GSFGQVV+A D + E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFE+L+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP+H++ + +A K+F + G + V + +DGKR ++ +RKL SI+G ETGGP GRR E GH+ DY F DLI RML DP RI P AL+H FF
Sbjct: 139 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPNHIMDLAPKARKFF-----EKLSDGTWS-------VKKTKDGKR--YKPPASRKLHSILGVETGGPGGRRAGESGHAVADYLKFKDLILRMLDYDPKSRIQPYYALQHSFF 469
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Medaka
Match: dyrk1b (dual specificity tyrosine-phosphorylation-regulated kinase 1B [Source:NCBI gene;Acc:101167568]) HSP 1 Score: 327.791 bits (839), Expect = 5.859e-99 Identity = 154/254 (60.63%), Postives = 199/254 (78.35%), Query Frame = 2
Query: 1463 LVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRAN 2224
+VK GE W++RY +D LIG GSFGQVV+A D E VAIKII+N+++F+ QA+ E+RLL ++ K+ + IV LK HFM+R HLCLVFELL+Y+LY+LL+NT+F GVSLNLT+KF QLC+AL FL+ P L IIHCDLKPEN+LL +PKRSAIK+VDFGSSC+L +R+Y YIQSRFYR+PEVLL +PY++AIDMWSLGCILVE+HTG+PLF G E +Q+ +I+EV G+PP HM+ + + N
Sbjct: 81 IVKNGEKWLDRYEIDSLIGKGSFGQVVKAYDHHEQEWVAIKIIKNKKAFLNQAQIELRLLELMNKHDTEMKYY---------IVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGVPPSHMLDAAPKKN 325
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Planmine SMEST
Match: SMESG000003953.1 (SMESG000003953.1) HSP 1 Score: 1599.72 bits (4141), Expect = 0.000e+0 Identity = 826/826 (100.00%), Postives = 826/826 (100.00%), Query Frame = 2
Query: 116 MFSTLNLKPTFPFKISKFTGFEKPRHLLSMDKDIPQYDDIRINDFPEHLFEHVDNSSPLDSETQXXXXXXXXALDKESLKKPMPVYGHIMTADQPQNVSLFCSKLTPSLSDGHISKADVLMDKWNDGISKFNFTDSSTSENRIVSADRRFFSEHSNYYDCCNIECNILSHKYSVESLETQNYDTISQESKSAFPMEDPTHFRXXXXXXXXXXXXIASQKLYELVSASNDNYRPESISASSDAQSYHSFGNESLFHHDVVGKQQPPIQKGTSLVFSTDKATAIRSVTTPVVFLCRPQESRILLRMTVSLIKTYQIINEMYYSKKRRRTTEHISSDDSFHRDTKRFLNTCNCSNNEVVQCHNDVDWCSKKRYXXXXXXXXXXXXXLQKPNDIQGNIDMXXXXXXXXXXXXXXXXXXXXNDSKIEKKHLPHDACCVPKCSHCNTNSSTAKEYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 2593
MFSTLNLKPTFPFKISKFTGFEKPRHLLSMDKDIPQYDDIRINDFPEHLFEHVDNSSPLDSETQSISSSFSIALDKESLKKPMPVYGHIMTADQPQNVSLFCSKLTPSLSDGHISKADVLMDKWNDGISKFNFTDSSTSENRIVSADRRFFSEHSNYYDCCNIECNILSHKYSVESLETQNYDTISQESKSAFPMEDPTHFRNTSQNSTTNLLTIASQKLYELVSASNDNYRPESISASSDAQSYHSFGNESLFHHDVVGKQQPPIQKGTSLVFSTDKATAIRSVTTPVVFLCRPQESRILLRMTVSLIKTYQIINEMYYSKKRRRTTEHISSDDSFHRDTKRFLNTCNCSNNEVVQCHNDVDWCSKKRYHHHHHRHNHHHHHLQKPNDIQGNIDMPPKRRHHKHLHPHHHHHKHLNDSKIEKKHLPHDACCVPKCSHCNTNSSTAKEYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS
Sbjct: 1 MFSTLNLKPTFPFKISKFTGFEKPRHLLSMDKDIPQYDDIRINDFPEHLFEHVDNSSPLDSETQSISSSFSIALDKESLKKPMPVYGHIMTADQPQNVSLFCSKLTPSLSDGHISKADVLMDKWNDGISKFNFTDSSTSENRIVSADRRFFSEHSNYYDCCNIECNILSHKYSVESLETQNYDTISQESKSAFPMEDPTHFRNTSQNSTTNLLTIASQKLYELVSASNDNYRPESISASSDAQSYHSFGNESLFHHDVVGKQQPPIQKGTSLVFSTDKATAIRSVTTPVVFLCRPQESRILLRMTVSLIKTYQIINEMYYSKKRRRTTEHISSDDSFHRDTKRFLNTCNCSNNEVVQCHNDVDWCSKKRYHHHHHRHNHHHHHLQKPNDIQGNIDMPPKRRHHKHLHPHHHHHKHLNDSKIEKKHLPHDACCVPKCSHCNTNSSTAKEYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFFCCAGRHSTLSSTADLTSIRNSPS 826
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Planmine SMEST
Match: SMESG000041146.1 (SMESG000041146.1) HSP 1 Score: 490.345 bits (1261), Expect = 8.552e-158 Identity = 227/356 (63.76%), Postives = 283/356 (79.49%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
EY +KPGE+W +RY ++ LIGTGSFGQVV+A D++T E VAIKII+N+++FV+QA+TEI LL +AKYQ ++ WG+N IV+LK+ F + GHLCLVFELLTY+LY+LLKNT+F GVSLNLT+KFG Q+C AL FLS+P LQIIHCDLKPEN+LL+HP+RSAIKVVDFGSSCR++ER+Y YIQSRFYR+PE++L + Y+ AID+WSLGCILVELHTGQPLF+GQ+EHEQILRI+E+ GMPP HM+ K+ KYF E I G IS++PK++R+RD K+I F GV +R L I+G TGGP GRR E GHS DY FLDL+ +ML +DP RI PE ALKHPFF
Sbjct: 264 EYFIKPGEIWKSRYYIEQLIGTGSFGQVVKARDMVTQENVAIKIIKNKKNFVEQAQTEIALLMEMAKYQITDEMAQ--EWGSNYIVKLKTTFTHHGHLCLVFELLTYNLYDLLKNTNFKGVSLNLTRKFGSQICEALAFLSKPQLQIIHCDLKPENILLIHPRRSAIKVVDFGSSCRVSERIYCYIQSRFYRSPEIILNVEYSQAIDIWSLGCILVELHTGQPLFIGQFEHEQILRIVELMGMPPSHMLMAGKKTYKYF-EQVI-----GTDGAISYQPKIYRDRDNKKISFRGVSSRNLCDILGVYTGGPFGRRASELGHSSTDYEKFLDLVQKMLVLDPEYRIKPEAALKHPFF 611
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Planmine SMEST
Match: SMESG000041146.1 (SMESG000041146.1) HSP 1 Score: 489.574 bits (1259), Expect = 9.981e-158 Identity = 227/356 (63.76%), Postives = 283/356 (79.49%), Query Frame = 2
Query: 1457 EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
EY +KPGE+W +RY ++ LIGTGSFGQVV+A D++T E VAIKII+N+++FV+QA+TEI LL +AKYQ ++ WG+N IV+LK+ F + GHLCLVFELLTY+LY+LLKNT+F GVSLNLT+KFG Q+C AL FLS+P LQIIHCDLKPEN+LL+HP+RSAIKVVDFGSSCR++ER+Y YIQSRFYR+PE++L + Y+ AID+WSLGCILVELHTGQPLF+GQ+EHEQILRI+E+ GMPP HM+ K+ KYF E I G IS++PK++R+RD K+I F GV +R L I+G TGGP GRR E GHS DY FLDL+ +ML +DP RI PE ALKHPFF
Sbjct: 255 EYFIKPGEIWKSRYYIEQLIGTGSFGQVVKARDMVTQENVAIKIIKNKKNFVEQAQTEIALLMEMAKYQITDEMAQ--EWGSNYIVKLKTTFTHHGHLCLVFELLTYNLYDLLKNTNFKGVSLNLTRKFGSQICEALAFLSKPQLQIIHCDLKPENILLIHPRRSAIKVVDFGSSCRVSERIYCYIQSRFYRSPEIILNVEYSQAIDIWSLGCILVELHTGQPLFIGQFEHEQILRIVELMGMPPSHMLMAGKKTYKYF-EQVI-----GTDGAISYQPKIYRDRDNKKISFRGVSSRNLCDILGVYTGGPFGRRASELGHSSTDYEKFLDLVQKMLVLDPEYRIKPEAALKHPFF 602
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Planmine SMEST
Match: SMESG000080906.1 (SMESG000080906.1) HSP 1 Score: 490.73 bits (1262), Expect = 7.096e-157 Identity = 264/510 (51.76%), Postives = 343/510 (67.25%), Query Frame = 2
Query: 1013 ILLRMTVSLIKTYQIINEMYYSKKRRRTTEHISSDDSFHRDTKRFLNTCNCSNNEVVQCHNDVDWCSKKRYXXXXXXXXXXXXXLQKPNDIQGNIDMXXXXXXXXXXXXXXXXXXXXNDSKIEKKHLPHDACCVPKCSHCNTNSSTAK------EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
IL++++V LIKTY+ INE+YY KKRR + + D+ +D KR N+ + N ++ + V C K +D I+ +D ++ +P + H N N+S + EYL+KPGE+W ++YS++ LIGTGSFGQVVRA DL +GE VAIKII+N+R+FV+QA EI LL+ + K+QE+ ++ WGAN IV+LKS F +RGHLCLVFELLTY+LYELLKNT+F GVSLNLT+KF Q+C AL FLS+P +QIIHCDLKPEN+LL+HP+RSAIKVVDFGSSC N R+Y YIQSRFYR+PE++L L Y+ AIDMWSLGCI+ ELHTGQPLF+GQ+EHEQILRIIEV GMPP+ MI K++ +YF + + ++ PK+ R +DGK+I F+G+ +RKLS IIG TGGP GRR +EPGHS DY FLDL+ +M+ IDP KRI P+EALKHPFF
Sbjct: 204 ILIKLSVDLIKTYKNINEIYYRKKRR--LKEPTDDNFLKKDRKR--NSGHEDNTDLKSSNQKVLSCDGAPQT--------------KNSDPSNEIN-----------KKFGCATLLHSDQRVP---IPQNFTLSGNVPHSNVNTSISSKDVGGYEYLIKPGEIWKSQYSIEKLIGTGSFGQVVRAKDLKSGEFVAIKIIKNKRNFVEQAYIEISLLKEIGKFQENDEIAQ--EWGANYIVKLKSFFNHRGHLCLVFELLTYTLYELLKNTNFRGVSLNLTRKFAQQICQALVFLSKPQVQIIHCDLKPENILLLHPRRSAIKVVDFGSSCHANRRIYYYIQSRFYRSPEIILNLDYSHAIDMWSLGCIMAELHTGQPLFIGQFEHEQILRIIEVVGMPPNTMIDSGKKSLRYF----DRFPSTNLQTKYTYRPKLHREKDGKKIAFQGISSRKLSDIIGVYTGGPQGRRLNEPGHSSLDYEKFLDLLQKMMVIDPKKRIKPDEALKHPFF 675
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Planmine SMEST
Match: SMESG000080906.1 (SMESG000080906.1) HSP 1 Score: 491.115 bits (1263), Expect = 7.746e-157 Identity = 264/510 (51.76%), Postives = 343/510 (67.25%), Query Frame = 2
Query: 1013 ILLRMTVSLIKTYQIINEMYYSKKRRRTTEHISSDDSFHRDTKRFLNTCNCSNNEVVQCHNDVDWCSKKRYXXXXXXXXXXXXXLQKPNDIQGNIDMXXXXXXXXXXXXXXXXXXXXNDSKIEKKHLPHDACCVPKCSHCNTNSSTAK------EYLVKPGEVWMNRYSMDLLIGTGSFGQVVRANDLITGEPVAIKIIRNRRSFVQQAETEIRLLRMLAKYQEDQDVVTVPHWGANCIVRLKSHFMYRGHLCLVFELLTYSLYELLKNTSFSGVSLNLTKKFGLQLCSALHFLSQPSLQIIHCDLKPENVLLVHPKRSAIKVVDFGSSCRLNERLYVYIQSRFYRAPEVLLYLPYNMAIDMWSLGCILVELHTGQPLFVGQYEHEQILRIIEVCGMPPDHMIRCSKRANKYFIESEIQMNESGNANHISHEPKVFRNRDGKRIPFEGVGARKLSSIIGTETGGPDGRRKDEPGHSPQDYACFLDLINRMLTIDPFKRITPEEALKHPFF 2524
IL++++V LIKTY+ INE+YY KKRR + + D+ +D KR N+ + N ++ + V C K +D I+ +D ++ +P + H N N+S + EYL+KPGE+W ++YS++ LIGTGSFGQVVRA DL +GE VAIKII+N+R+FV+QA EI LL+ + K+QE+ ++ WGAN IV+LKS F +RGHLCLVFELLTY+LYELLKNT+F GVSLNLT+KF Q+C AL FLS+P +QIIHCDLKPEN+LL+HP+RSAIKVVDFGSSC N R+Y YIQSRFYR+PE++L L Y+ AIDMWSLGCI+ ELHTGQPLF+GQ+EHEQILRIIEV GMPP+ MI K++ +YF + + ++ PK+ R +DGK+I F+G+ +RKLS IIG TGGP GRR +EPGHS DY FLDL+ +M+ IDP KRI P+EALKHPFF
Sbjct: 216 ILIKLSVDLIKTYKNINEIYYRKKRR--LKEPTDDNFLKKDRKR--NSGHEDNTDLKSSNQKVLSCDGAPQT--------------KNSDPSNEIN-----------KKFGCATLLHSDQRVP---IPQNFTLSGNVPHSNVNTSISSKDVGGYEYLIKPGEIWKSQYSIEKLIGTGSFGQVVRAKDLKSGEFVAIKIIKNKRNFVEQAYIEISLLKEIGKFQENDEIAQ--EWGANYIVKLKSFFNHRGHLCLVFELLTYTLYELLKNTNFRGVSLNLTRKFAQQICQALVFLSKPQVQIIHCDLKPENILLLHPRRSAIKVVDFGSSCHANRRIYYYIQSRFYRSPEIILNLDYSHAIDMWSLGCIMAELHTGQPLFIGQFEHEQILRIIEVVGMPPNTMIDSGKKSLRYF----DRFPSTNLQTKYTYRPKLHREKDGKKIAFQGISSRKLSDIIGVYTGGPQGRRLNEPGHSSLDYEKFLDLLQKMMVIDPKKRIKPDEALKHPFF 687 The following BLAST results are available for this feature:
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dual specificity tyrosine-phosphorylation-regulated kinase 1A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012260 ID=SMED30012260|Name=Dual specificity tyrosine-phosphorylation-regulated kinase 1A|organism=Schmidtea mediterranea sexual|type=transcript|length=3845bpback to top protein sequence of SMED30012260-orf-1 >SMED30012260-orf-1 ID=SMED30012260-orf-1|Name=SMED30012260-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=833bp MENQTNMFSTLNLKPTFPFKISKFTGFEKPRHLLSMDKDIPQYDDIRINDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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