Protein disulfide-isomerase

Overview


Name	Protein disulfide-isomerase
Smed ID	SMED30012219
Length (bp)	2291

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein disulfide-isomerase (SMED30012219) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein disulfide-isomerase (SMED30012219) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein disulfide-isomerase (SMED30012219) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein disulfide-isomerase (SMED30012219) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012219

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30012219	SMESG000076091.1 SMESG000076042.1 SMESG000074857.1 SMESG000069936.1 SMESG000048922.1 SMESG000026530.1 SMESG000022236.1 SMESG000021499.1 SMESG000008351.1 SMESG000006220.1	Contig100	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30012219	SMESG000076091.1 SMESG000076042.1 SMESG000074857.1 SMESG000069936.1 SMESG000048922.1 SMESG000026530.1 SMESG000022236.1 SMESG000021499.1 SMESG000008351.1 SMESG000006220.1	Contig100	GPL15192	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30012219	SMESG000041085.1	Contig100	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30012219	SMESG000041085.1	Contig100	GPL15192	PMID:23079596 Forsthoefel et al., 2012
nervous system	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30012219	SMESG000041085.1	dd_Smed_v4_426_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30012219	SMESG000041085.1	dd_Smed_v6_426_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
secretory system	SMED30012219	SMESG000041085.1	dd_Smed_v6_426_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: PDIA3 (protein disulfide isomerase family A member 3 [Source:HGNC Symbol;Acc:HGNC:4606])

HSP 1 Score: 287.73 bits (735), Expect = 5.893e-88
Identity = 135/247 (54.66%), Postives = 178/247 (72.06%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             G+  H T  N      + L++A Y+VDYEKN KG+NYWRNR++ VAKKF+D+G  ++FA+++ +  + ELS++G+ES       +  R  + +KF M  +FS +   LE+F+ D+    +  YLKSE IPE ND PVKVVVA+NFDEIVN+  KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y  GRE+ D + Y+  EA++P
Sbjct:  241 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNP 487

HSP 2 Score: 191.045 bits (484), Expect = 3.942e-52
Identity = 95/200 (47.50%), Postives = 134/200 (67.00%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN---IVIFHSKKMANKFEDTQVKY-KGDASEHQIRTWVEENM 596
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ A  Y G R+ADGI+ ++  ++GP+S  L+TEE F KF +  D  +VGFF    S+ +  FL  A  L +++RFAHT  E+L  +  Y +N   I++F    + NKFED  V Y +   +  +I+ +++EN+
Sbjct:   46 GLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNE--YDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI 240

HSP 3 Score: 70.4774 bits (171), Expect = 5.305e-12
Identity = 41/111 (36.94%), Postives = 64/111 (57.66%), Query Frame = 1

Query: 1840 NFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLK 2154
            NF+  ++D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++   A  AS PL+
Sbjct:   34 NFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQAGPASVPLR 140

HSP 4 Score: 65.0846 bits (157), Expect = 2.857e-10
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            E+  +L+EFYAPWCGHCK L P+Y+     L K DP I IAK+D TA       + V G+PT+
Sbjct:  393 ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKMDATA-NDVPSPYEVRGFPTI 453

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: PDIA4 (protein disulfide isomerase family A member 4 [Source:HGNC Symbol;Acc:HGNC:30167])

HSP 1 Score: 199.519 bits (506), Expect = 4.043e-54
Identity = 111/249 (44.58%), Postives = 155/249 (62.25%), Query Frame = 1

Query: 1411 SMGLAGHRTHSN-VKYFAKRPLIVALYNVDYEKNPKG-TNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKM-IADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSP-YEVSGFPTIYFAPKNSKHSPKSYSSG-REVDDMLKYIASEAS 2142
            ++ L GHR  SN  K + +RPL+V  Y+VD+  + +  T +WR+++L+VAK F +      FAI++ ++   E+ + G+ S     V     DE  +KF M   +F  + L +F+  F + K+   +KS+ +P+ N  PVKVVV K FD IV DP KDVLIEFYAPWCGHCK L P Y  LAKK   +  +VIAKMDATANDVPS  Y+V GFPTIYFAP   K +P  +  G R+++ + K+I   A+
Sbjct:  394 ALPLVGHRKVSNDAKRYTRRPLVVVYYSVDFSFDYRAATQFWRSKVLEVAKDFPE----YTFAIADEEDYAGEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHAT 637

HSP 2 Score: 169.859 bits (429), Expect = 7.598e-44
Identity = 82/174 (47.13%), Postives = 112/174 (64.37%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPV-VVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNY-KNNIVIFHSKKMANKFE 527
            +ILVEFYAPWCGHCKKLAPEYE AA  L K+ PPI +AKVD TAET   ++  VSGYPTLK+F+ G+  +DY+G R   GI+ YM+ +SGP SKE+ T +   +F    D V ++G F  ES   Y+ +   A  L ED++F HTF   ++  L   +  +V+   +K  +K+E
Sbjct:  196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQPEKFQSKYE 368

HSP 3 Score: 112.079 bits (279), Expect = 6.001e-25
Identity = 54/126 (42.86%), Postives = 77/126 (61.11%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKE------LKTEENFNKFTASADPVVVGFF 362
            +   +L+EFYAPWCGHCK+ APEYE  A  LK +DPPI +AK+D T+ +    +  VSGYPT+K+ K GQ A DY G R+ + I+  +   S P          + T+ENF++    AD ++V F+
Sbjct:   78 DKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFY 202

HSP 4 Score: 93.2041 bits (230), Expect = 5.806e-19
Identity = 58/136 (42.65%), Postives = 84/136 (61.76%), Query Frame = 1

Query: 1759 QEKVPVYLKSESIPEKNDEP-VKVVVAK-NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLK 2154
            QE++   ++  S P+    P V +V+ K NFDE+VND    +L+EFYAPWCGHCK LAP+YE+ AK+LS  S  I +AK+DATA  D+   ++VSG+PT+       K  P  Y+  RE   ++ Y+  ++  P K
Sbjct:  157 QEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVND-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIF---RKGRPYDYNGPREKYGIVDYMIEQSGPPSK 288

HSP 5 Score: 73.1738 bits (178), Expect = 9.932e-13
Identity = 42/79 (53.16%), Postives = 54/79 (68.35%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATANDV-PSPYEVSGFPTI 2046
            V V+   NFD  V D  KD VL+EFYAPWCGHCK  AP+YE++A  L   +  I +AK+DAT+  V  S ++VSG+PTI
Sbjct:   64 VLVLNDANFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTI 140

HSP 6 Score: 63.929 bits (154), Expect = 8.984e-10
Identity = 28/59 (47.46%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK+L P Y   A   K Q   + IAK+D TA     +++ V G+PT+
Sbjct:  547 VLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDVPSDRYKVEGFPTI 604

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: PDIA4 (protein disulfide isomerase family A member 4 [Source:HGNC Symbol;Acc:HGNC:30167])

HSP 1 Score: 199.519 bits (506), Expect = 4.099e-54
Identity = 111/249 (44.58%), Postives = 155/249 (62.25%), Query Frame = 1

Query: 1411 SMGLAGHRTHSN-VKYFAKRPLIVALYNVDYEKNPKG-TNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKM-IADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSP-YEVSGFPTIYFAPKNSKHSPKSYSSG-REVDDMLKYIASEAS 2142
            ++ L GHR  SN  K + +RPL+V  Y+VD+  + +  T +WR+++L+VAK F +      FAI++ ++   E+ + G+ S     V     DE  +KF M   +F  + L +F+  F + K+   +KS+ +P+ N  PVKVVV K FD IV DP KDVLIEFYAPWCGHCK L P Y  LAKK   +  +VIAKMDATANDVPS  Y+V GFPTIYFAP   K +P  +  G R+++ + K+I   A+
Sbjct:  393 ALPLVGHRKVSNDAKRYTRRPLVVVYYSVDFSFDYRAATQFWRSKVLEVAKDFPE----YTFAIADEEDYAGEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHAT 636

HSP 2 Score: 169.859 bits (429), Expect = 8.818e-44
Identity = 85/195 (43.59%), Postives = 120/195 (61.54%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPV-VVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNY-KNNIVIFHSKKMANKFEDT--QVKYKGDASEHQIRTWV 584
            +ILVEFYAPWCGHCKKLAPEYE AA  L K+ PPI +AKVD TAET   ++  VSGYPTLK+F+ G+  +DY+G R   GI+ YM+ +SGP SKE+ T +   +F    D V ++G F  ES   Y+ +   A  L ED++F HTF   ++  L   +  +V+   +K  +K+E     +  +G   +  I+ +V
Sbjct:  196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGR-PYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSAIKDFV 389

HSP 3 Score: 111.694 bits (278), Expect = 7.926e-25
Identity = 54/126 (42.86%), Postives = 77/126 (61.11%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKE------LKTEENFNKFTASADPVVVGFF 362
            +   +L+EFYAPWCGHCK+ APEYE  A  LK +DPPI +AK+D T+ +    +  VSGYPT+K+ K GQ A DY G R+ + I+  +   S P          + T+ENF++    AD ++V F+
Sbjct:   78 DKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQ-AVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFY 202

HSP 4 Score: 93.2041 bits (230), Expect = 5.946e-19
Identity = 58/136 (42.65%), Postives = 84/136 (61.76%), Query Frame = 1

Query: 1759 QEKVPVYLKSESIPEKNDEP-VKVVVAK-NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLK 2154
            QE++   ++  S P+    P V +V+ K NFDE+VND    +L+EFYAPWCGHCK LAP+YE+ AK+LS  S  I +AK+DATA  D+   ++VSG+PT+       K  P  Y+  RE   ++ Y+  ++  P K
Sbjct:  157 QEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVND-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIF---RKGRPYDYNGPREKYGIVDYMIEQSGPPSK 288

HSP 5 Score: 73.1738 bits (178), Expect = 1.000e-12
Identity = 42/79 (53.16%), Postives = 54/79 (68.35%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATANDV-PSPYEVSGFPTI 2046
            V V+   NFD  V D  KD VL+EFYAPWCGHCK  AP+YE++A  L   +  I +AK+DAT+  V  S ++VSG+PTI
Sbjct:   64 VLVLNDANFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTI 140

HSP 6 Score: 63.5438 bits (153), Expect = 1.012e-9
Identity = 28/59 (47.46%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK+L P Y   A   K Q   + IAK+D TA     +++ V G+PT+
Sbjct:  546 VLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK-GLVIAKMDATANDVPSDRYKVEGFPTI 603

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: P4HB (prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548])

HSP 1 Score: 132.88 bits (333), Expect = 4.618e-32
Identity = 72/199 (36.18%), Postives = 113/199 (56.78%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAF--DYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNY-KNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            H  +LVEFYAPWCGHCK LAPEY  AA  LK +   I +AKVD T E+   +++GV GYPT+K F+NG  A   +Y+  R AD I+ ++  ++GP++  L           S++  V+GFF    SD  K FL  AE ++ D  F  T +  + +K    K+ +V+F       KF++ +  ++G+ ++  +  +++ N
Sbjct:   41 HKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAID-DIPFGITSNSDVFSKYQLDKDGVVLF------KKFDEGRNNFEGEVTKENLLDFIKHN 232

HSP 2 Score: 124.79 bits (312), Expect = 1.993e-29
Identity = 69/190 (36.32%), Postives = 114/190 (60.00%), Query Frame = 1

Query: 1573 GKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFKMIAD-FSMENLEKFINDFLQEKVPVYLKSESIPEKND-EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIAS 2133
            GK +   I +    NQ + E+ G++  +   V +   +E   K+K  ++  + E + +F + FL+ K+  +L S+ +PE  D +PVKV+V KNF+++  D  K+V +EFYAPWCGHCK LAP +++L +      +IVIAKMD+TAN+V +  +V  FPT+ F P ++  +   Y+  R +D   K++ S
Sbjct:  284 GKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 472

HSP 3 Score: 100.138 bits (248), Expect = 2.200e-21
Identity = 54/112 (48.21%), Postives = 74/112 (66.07%), Query Frame = 1

Query: 1798 PEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            PE+ D  V V+   NF E +    K +L+EFYAPWCGHCK+LAP+Y + A KL AE S+I +AK+DAT  +D+   Y V G+PTI F       SPK Y++GRE DD++ ++
Sbjct:   20 PEEEDH-VLVLRKSNFAEALA-AHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWL 129

HSP 4 Score: 71.2478 bits (173), Expect = 3.611e-12
Identity = 39/88 (44.32%), Postives = 51/88 (57.95%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYMVS 272
            + VEFYAPWCGHCK+LAP ++      K  +  I IAK+D TA     E   V  +PTLK F     +   DY+GER+ DG  K++ S
Sbjct:  388 VFVEFYAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTA--NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 472

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Human
Match: P4HB (prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548])

HSP 1 Score: 124.79 bits (312), Expect = 3.422e-31
Identity = 69/190 (36.32%), Postives = 114/190 (60.00%), Query Frame = 1

Query: 1573 GKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFKMIAD-FSMENLEKFINDFLQEKVPVYLKSESIPEKND-EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIAS 2133
            GK +   I +    NQ + E+ G++  +   V +   +E   K+K  ++  + E + +F + FL+ K+  +L S+ +PE  D +PVKV+V KNF+++  D  K+V +EFYAPWCGHCK LAP +++L +      +IVIAKMD+TAN+V +  +V  FPT+ F P ++  +   Y+  R +D   K++ S
Sbjct:   50 GKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 238

HSP 2 Score: 72.0182 bits (175), Expect = 4.129e-13
Identity = 39/88 (44.32%), Postives = 51/88 (57.95%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYMVS 272
            + VEFYAPWCGHCK+LAP ++      K  +  I IAK+D TA     E   V  +PTLK F     +   DY+GER+ DG  K++ S
Sbjct:  154 VFVEFYAPWCGHCKQLAPIWDKLGETYKDHE-NIVIAKMDSTA--NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 238

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-3 (pep chromosome:WBcel235:I:7015912:7021743:-1 gene:WBGene00003964.1 transcript:H06O01.1.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:pdi-3)

HSP 1 Score: 258.455 bits (659), Expect = 1.835e-77
Identity = 126/258 (48.84%), Postives = 179/258 (69.38%), Query Frame = 1

Query: 1411 SMGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRK 2184
            ++G AG RT  N+  F ++P+++  YNVDY K+PKG+NYWRNR+LKVA+ +    + + FA+SN +E + E+   G+     S   I A      K+ M  +FS++NL++F+++ L      Y+KSE IP++  + VKV V KNF E++ D  KDVLIEFYAPWCGHCKSLAPKYEELA+KL+ E D++IAKMDATANDVP  +EV GFPT+++ PKN+K +P  Y+ GREV D + +I+  ++  LK F R G+ +K
Sbjct:  232 TVGFAGIRTQGNLFQFEQKPIVIVYYNVDYVKDPKGSNYWRNRVLKVAQNY---KRKVQFAVSNKEEFSSEIETNGLGERKDSDKPIVAILTNEGKYPMDQEFSVDNLQQFVDEVLAGNAEPYMKSEPIPDEQGD-VKVAVGKNFKELIMDADKDVLIEFYAPWCGHCKSLAPKYEELAEKLNKE-DVIIAKMDATANDVPPMFEVRGFPTLFWLPKNAKSNPIPYNGGREVKDFVSFISKHSTDGLKGFSRDGKKKK 484

HSP 2 Score: 212.231 bits (539), Expect = 1.754e-60
Identity = 110/237 (46.41%), Postives = 148/237 (62.45%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM*VNYVQIRXXXXXXXXXXKP*TLI---GRHVLTNKGHHKW 707
            H + LV+FYAPWCGHCKK+APEYE AA  L   DPP+A+ KVDCT E   C+K GV G+PTLK+F+NG  A DY G R ADGI+K+M  +SGPSSKELKT   F KFT   + VV+GFF SES  L  ++L VA+   + F FAHT ++ +  K  Y +++V+F  KK+ NKF+  + KY G+    +I+ ++     V +  IR    L  F  KP  ++     +V   KG + W
Sbjct:   37 HDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIFRNGVPAQDYDGPRDADGIVKFMRGQSGPSSKELKTVAEFEKFTGGDENVVIGFFESESK-LKDSYLKVADTERDRFSFAHTSNKDIIKKAGYSDDVVVFVPKKLHNKFDTNEFKYDGNYDTDKIKNFLVHET-VGFAGIRTQGNLFQFEQKPIVIVYYNVDYVKDPKGSNYW 271

HSP 3 Score: 68.5514 bits (166), Expect = 9.538e-12
Identity = 36/104 (34.62%), Postives = 61/104 (58.65%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDV-LIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NFD+++   T D+ L++FYAPWCGHCK +AP+YE  A KL++ +  + + K+D T    V   + V GFPT+      +    + Y   R+ D ++K++  ++ 
Sbjct:   29 NFDDLIQ--THDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIF--RNGVPAQDYDGPRDADGIVKFMRGQSG 128

HSP 4 Score: 66.2402 bits (160), Expect = 4.744e-11
Identity = 32/59 (54.24%), Postives = 39/59 (66.10%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK LAP+YE  A  L K+D  + IAK+D TA         V G+PTL
Sbjct:  383 VLIEFYAPWCGHCKSLAPKYEELAEKLNKED--VIIAKMDATA-NDVPPMFEVRGFPTL 438

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-3 (pep chromosome:WBcel235:I:7015912:7020790:-1 gene:WBGene00003964.1 transcript:H06O01.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:pdi-3)

HSP 1 Score: 258.455 bits (659), Expect = 1.835e-77
Identity = 126/258 (48.84%), Postives = 179/258 (69.38%), Query Frame = 1

Query: 1411 SMGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRK 2184
            ++G AG RT  N+  F ++P+++  YNVDY K+PKG+NYWRNR+LKVA+ +    + + FA+SN +E + E+   G+     S   I A      K+ M  +FS++NL++F+++ L      Y+KSE IP++  + VKV V KNF E++ D  KDVLIEFYAPWCGHCKSLAPKYEELA+KL+ E D++IAKMDATANDVP  +EV GFPT+++ PKN+K +P  Y+ GREV D + +I+  ++  LK F R G+ +K
Sbjct:  232 TVGFAGIRTQGNLFQFEQKPIVIVYYNVDYVKDPKGSNYWRNRVLKVAQNY---KRKVQFAVSNKEEFSSEIETNGLGERKDSDKPIVAILTNEGKYPMDQEFSVDNLQQFVDEVLAGNAEPYMKSEPIPDEQGD-VKVAVGKNFKELIMDADKDVLIEFYAPWCGHCKSLAPKYEELAEKLNKE-DVIIAKMDATANDVPPMFEVRGFPTLFWLPKNAKSNPIPYNGGREVKDFVSFISKHSTDGLKGFSRDGKKKK 484

HSP 2 Score: 212.231 bits (539), Expect = 1.754e-60
Identity = 110/237 (46.41%), Postives = 148/237 (62.45%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM*VNYVQIRXXXXXXXXXXKP*TLI---GRHVLTNKGHHKW 707
            H + LV+FYAPWCGHCKK+APEYE AA  L   DPP+A+ KVDCT E   C+K GV G+PTLK+F+NG  A DY G R ADGI+K+M  +SGPSSKELKT   F KFT   + VV+GFF SES  L  ++L VA+   + F FAHT ++ +  K  Y +++V+F  KK+ NKF+  + KY G+    +I+ ++     V +  IR    L  F  KP  ++     +V   KG + W
Sbjct:   37 HDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIFRNGVPAQDYDGPRDADGIVKFMRGQSGPSSKELKTVAEFEKFTGGDENVVIGFFESESK-LKDSYLKVADTERDRFSFAHTSNKDIIKKAGYSDDVVVFVPKKLHNKFDTNEFKYDGNYDTDKIKNFLVHET-VGFAGIRTQGNLFQFEQKPIVIVYYNVDYVKDPKGSNYW 271

HSP 3 Score: 68.5514 bits (166), Expect = 9.538e-12
Identity = 36/104 (34.62%), Postives = 61/104 (58.65%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDV-LIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NFD+++   T D+ L++FYAPWCGHCK +AP+YE  A KL++ +  + + K+D T    V   + V GFPT+      +    + Y   R+ D ++K++  ++ 
Sbjct:   29 NFDDLIQ--THDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIF--RNGVPAQDYDGPRDADGIVKFMRGQSG 128

HSP 4 Score: 66.2402 bits (160), Expect = 4.744e-11
Identity = 32/59 (54.24%), Postives = 39/59 (66.10%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK LAP+YE  A  L K+D  + IAK+D TA         V G+PTL
Sbjct:  383 VLIEFYAPWCGHCKSLAPKYEELAEKLNKED--VIIAKMDATA-NDVPPMFEVRGFPTL 438

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-3 (pep chromosome:WBcel235:I:7015912:7020797:-1 gene:WBGene00003964.1 transcript:H06O01.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:pdi-3)

HSP 1 Score: 258.455 bits (659), Expect = 1.835e-77
Identity = 126/258 (48.84%), Postives = 179/258 (69.38%), Query Frame = 1

Query: 1411 SMGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRK 2184
            ++G AG RT  N+  F ++P+++  YNVDY K+PKG+NYWRNR+LKVA+ +    + + FA+SN +E + E+   G+     S   I A      K+ M  +FS++NL++F+++ L      Y+KSE IP++  + VKV V KNF E++ D  KDVLIEFYAPWCGHCKSLAPKYEELA+KL+ E D++IAKMDATANDVP  +EV GFPT+++ PKN+K +P  Y+ GREV D + +I+  ++  LK F R G+ +K
Sbjct:  232 TVGFAGIRTQGNLFQFEQKPIVIVYYNVDYVKDPKGSNYWRNRVLKVAQNY---KRKVQFAVSNKEEFSSEIETNGLGERKDSDKPIVAILTNEGKYPMDQEFSVDNLQQFVDEVLAGNAEPYMKSEPIPDEQGD-VKVAVGKNFKELIMDADKDVLIEFYAPWCGHCKSLAPKYEELAEKLNKE-DVIIAKMDATANDVPPMFEVRGFPTLFWLPKNAKSNPIPYNGGREVKDFVSFISKHSTDGLKGFSRDGKKKK 484

HSP 2 Score: 212.231 bits (539), Expect = 1.754e-60
Identity = 110/237 (46.41%), Postives = 148/237 (62.45%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM*VNYVQIRXXXXXXXXXXKP*TLI---GRHVLTNKGHHKW 707
            H + LV+FYAPWCGHCKK+APEYE AA  L   DPP+A+ KVDCT E   C+K GV G+PTLK+F+NG  A DY G R ADGI+K+M  +SGPSSKELKT   F KFT   + VV+GFF SES  L  ++L VA+   + F FAHT ++ +  K  Y +++V+F  KK+ NKF+  + KY G+    +I+ ++     V +  IR    L  F  KP  ++     +V   KG + W
Sbjct:   37 HDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIFRNGVPAQDYDGPRDADGIVKFMRGQSGPSSKELKTVAEFEKFTGGDENVVIGFFESESK-LKDSYLKVADTERDRFSFAHTSNKDIIKKAGYSDDVVVFVPKKLHNKFDTNEFKYDGNYDTDKIKNFLVHET-VGFAGIRTQGNLFQFEQKPIVIVYYNVDYVKDPKGSNYW 271

HSP 3 Score: 68.5514 bits (166), Expect = 9.538e-12
Identity = 36/104 (34.62%), Postives = 61/104 (58.65%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDV-LIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NFD+++   T D+ L++FYAPWCGHCK +AP+YE  A KL++ +  + + K+D T    V   + V GFPT+      +    + Y   R+ D ++K++  ++ 
Sbjct:   29 NFDDLIQ--THDIALVKFYAPWCGHCKKIAPEYERAAPKLASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIF--RNGVPAQDYDGPRDADGIVKFMRGQSG 128

HSP 4 Score: 66.2402 bits (160), Expect = 4.744e-11
Identity = 32/59 (54.24%), Postives = 39/59 (66.10%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK LAP+YE  A  L K+D  + IAK+D TA         V G+PTL
Sbjct:  383 VLIEFYAPWCGHCKSLAPKYEELAEKLNKED--VIIAKMDATA-NDVPPMFEVRGFPTL 438

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: C14B9.2 (Probable protein disulfide-isomerase A4 [Source:UniProtKB/Swiss-Prot;Acc:P34329])

HSP 1 Score: 173.711 bits (439), Expect = 1.137e-45
Identity = 106/261 (40.61%), Postives = 151/261 (57.85%), Query Frame = 1

Query: 1411 SMGLAGHRTHSNV-KYFAKRPLIVALYNVDYE-KNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFS-KVYITARDERNQKFKMIAD-FSME---NLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQ 2169
            S  L G  T  N    + K+PL+V  YN D+  +  +G+ YWR+++L +A+K+        FA+++ +E  +EL E G+        V +   D   +K+ M  D F  E   NLE F+      K   ++KS   P+ +  PVK VV  NFD+IVND +KDVLIEFYAPWCGHCKS   KY ELA+ L   + ++V+AKMDAT ND PS + V GFPTIYFAP   K  P  YS  R+++D+ K++       +K+F ++
Sbjct:  362 SAPLVGKMTKKNAATRYTKKPLVVVYYNADFSVQYREGSEYWRSKVLNIAQKY--QKDKYKFAVADEEEFAKELEELGLGDSGLEHNVVVFGYD--GKKYPMNPDEFDGELDENLEAFMKQISSGKAKAHVKSAPAPKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDAPSQFAVEGFPTIYFAPAGKKSEPIKYSGNRDLEDLKKFMTKHG---VKSFQKK 615

HSP 2 Score: 163.696 bits (413), Expect = 2.878e-42
Identity = 84/182 (46.15%), Postives = 115/182 (63.19%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFR-FAHTFDETLSTKLNYK-NNIVIFHSKKMANKFEDTQVKY 545
            + ++LVEFYAPWCGHCKKLAPEYE AA  LK Q   + + KVD T E     K+GVSGYPT+K+ +NG+  FDY+G R A GIIKYM  +S P++K+L   ++  +F +  D  ++GFF +E S  ++AF   AE L E+F+   HT D     K + K N+I+IF+     +KFE     Y
Sbjct:  164 NELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNGR-RFDYNGPREAAGIIKYMTDQSKPAAKKLPKLKDVERFMSKDDVTIIGFFATEDSTAFEAFSDSAEMLREEFKTMGHTSDPAAFKKWDAKPNDIIIFYPSLFHSKFEPKSRTY 344

HSP 3 Score: 102.064 bits (253), Expect = 3.747e-22
Identity = 52/122 (42.62%), Postives = 77/122 (63.11%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTE------ENFNKFTASADPVVVGFF 362
            +LV+FYAPWCGHCK LAPEYE A++ +      I +AKVD T ET+  ++  + GYPTLK +K+G+   DY G R   GI++++ S+  P+ K    E      ENF+ F ++ + V+V F+
Sbjct:   56 VLVKFYAPWCGHCKHLAPEYEKASSKVS-----IPLAKVDATVETELGKRFEIQGYPTLKFWKDGKGPNDYDGGRDEAGIVEWVESRVDPNYKPPPEEVVTLTTENFDDFISNNELVLVEFY 172

HSP 4 Score: 83.5741 bits (205), Expect = 2.040e-16
Identity = 44/111 (39.64%), Postives = 70/111 (63.06%), Query Frame = 1

Query: 1813 EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEA 2139
            E V  +  +NFD+ +++  + VL+EFYAPWCGHCK LAP+YE+ A+KL A+ S + + K+DAT   D+ + Y VSG+PT+       +     Y+  RE   ++KY+  ++
Sbjct:  147 EEVVTLTTENFDDFISN-NELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNGRRF---DYNGPREAAGIIKYMTDQS 253

HSP 5 Score: 81.2629 bits (199), Expect = 1.273e-15
Identity = 46/110 (41.82%), Postives = 71/110 (64.55%), Query Frame = 1

Query: 1810 DEPVKVVVAKNFDEIVN-DPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIAS 2133
            DE V V+  KNFD  +  +P+  VL++FYAPWCGHCK LAP+YE+ + K+S    I +AK+DAT   ++   +E+ G+PT+ F  K+ K  P  Y  GR+   +++++ S
Sbjct:   35 DEGVVVLTDKNFDAFLKKNPS--VLVKFYAPWCGHCKHLAPEYEKASSKVS----IPLAKVDATVETELGKRFEIQGYPTLKFW-KDGK-GPNDYDGGRDEAGIVEWVES 136

HSP 6 Score: 67.781 bits (164), Expect = 1.668e-11
Identity = 40/104 (38.46%), Postives = 56/104 (53.85%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFA--FDYSGERSADGIIKYMVSKSGPSSKELKTE 308
            E   +L+EFYAPWCGHCK    +Y   A ALKK  P + +AK+D T      +   V G+PT+     G+ +    YSG R  + + K+M +K G  S + K E
Sbjct:  516 ESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDAPSQ-FAVEGFPTIYFAPAGKKSEPIKYSGNRDLEDLKKFM-TKHGVKSFQKKDE 617

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Match: pdi-2 (Protein disulfide-isomerase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q17770])

HSP 1 Score: 143.665 bits (361), Expect = 3.165e-36
Identity = 77/194 (39.69%), Postives = 115/194 (59.28%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            ILVEFYAPWCGHCK LAPEY  AAT LK++   I + K+D T   +   K  V GYPTLK+F+NG+   +Y+G R  D II ++  K+GP +K L   +   +   SAD VV+G+F   +SD  K FL VA  ++ D  F  + ++ + +++  K   IV+F       KF+D +V +    ++  ++TW++ N
Sbjct:   43 ILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLFRNGK-PQEYNGGRDHDSIIAWLKKKTGPVAKPLADADAVKELQESADVVVIGYFKDTTSDDAKTFLEVAAGID-DVPFGISTEDAVKSEIELKGEGIVLFK------KFDDGRVAFDEKLTQDGLKTWIQAN 228

HSP 2 Score: 132.494 bits (332), Expect = 1.866e-32
Identity = 75/197 (38.07%), Postives = 118/197 (59.90%), Query Frame = 1

Query: 1552 AKKFIDSGKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFK-MIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDE-PVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIAS 2133
            AK+F   GK +   I+   E N  + E+ G++  +   + + + +E   KFK    + + EN+ KF  ++L   V  +L SE IPE  D+ PVK++V KNF+++  D TK+VL+EFYAPWCGHCK LAP +++L +K + +  IVIAKMD+T N+V    ++  FPTI F P  S +    Y+  R ++   K++ +
Sbjct:  275 AKQF--KGKVLFVYINTDVEENARIMEFFGLKKDELPAIRLISLEEDMTKFKPDFEEITTENISKFTQNYLDGSVKPHLMSEDIPEDWDKNPVKILVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNEVED-VKIQSFPTIKFFPAGS-NKVVDYTGDRTIEGFTKFLET 467

HSP 3 Score: 95.1301 bits (235), Expect = 3.157e-20
Identity = 52/123 (42.28%), Postives = 78/123 (63.41%), Query Frame = 1

Query: 1810 DEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLKNFD 2163
            +E V V+   NFDE++N   + +L+EFYAPWCGHCKSLAP+Y + A +L  E SDI + K+DAT   +V S +EV G+PT+    +N K  P+ Y+ GR+ D ++ ++       + PL + D
Sbjct:   22 EENVIVLTKDNFDEVING-NEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDATVHGEVSSKFEVRGYPTLKLF-RNGK--PQEYNGGRDHDSIIAWLKKKTGPVAKPLADAD 140

HSP 4 Score: 71.2478 bits (173), Expect = 1.310e-12
Identity = 35/85 (41.18%), Postives = 49/85 (57.65%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQF-AFDYSGERSADGIIKYM 266
            +LVEFYAPWCGHCK+LAP ++         D  I IAK+D T      E   +  +PT+K F  G     DY+G+R+ +G  K++
Sbjct:  384 VLVEFYAPWCGHCKQLAPTWDKLGEKF-ADDESIVIAKMDST--LNEVEDVKIQSFPTIKFFPAGSNKVVDYTGDRTIEGFTKFL 465

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: ERp60 (gene:FBgn0033663 transcript:FBtr0088058)

HSP 1 Score: 296.975 bits (759), Expect = 5.952e-92
Identity = 149/261 (57.09%), Postives = 192/261 (73.56%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDF--SKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            GL GHRT  +VK F + PLI A Y+VDY+KNPKGTNYWRNR+LKVAK+F+     I+FAI++  +   EL+EYG    DF   K  + ARDE+N K+ +  +FS+ENL+ F+   L  ++  Y+KSE IPE ND PVKV VAKNFD++V +  KD LIEFYAPWCGHCK L+P YEELA+KL  E D+ I KMDATANDVP  + V GFPT+++ PK++K+ P SY+ GREVDD LKYIA EA++ LK FDR G+ +K++L
Sbjct:  237 GLVGHRTQDSVKDF-QNPLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQ---INFAIASKDDFQHELNEYGY---DFVGDKPVVLARDEKNLKYALKDEFSVENLQDFVEKLLANELEPYIKSEPIPESNDAPVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQDE-DVAIVKMDATANDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYIAKEATTELKGFDRSGKPKKTEL 489

HSP 2 Score: 184.111 bits (466), Expect = 3.342e-50
Identity = 89/198 (44.95%), Postives = 128/198 (64.65%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCT-AETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            +H   LV FYAPWCGHCK+L PEY  AA  +K  DPPI +AKVDCT A  +TC K+ VSGYPTLK+F+  + + DY+G R A GI KYM ++ GP+SK ++T     KF  + D  + G+F+   S L K FL  A+K  E +RF H+ ++ +  K    + IV+  +  ++NKFE + +K++G +SE  + T+V+EN
Sbjct:   38 QHETTLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIAKYMRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGETDKIVLIRAPHLSNKFESSSIKFEG-SSESDLSTFVKEN 234

HSP 3 Score: 71.2478 bits (173), Expect = 1.344e-12
Identity = 42/91 (46.15%), Postives = 53/91 (58.24%), Query Frame = 3

Query:   18 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL----KVFKNGQFAFDYSGERSADGIIKYMVSKS 278
            L+EFYAPWCGHCKKL+P YE  A  L  QD  +AI K+D TA     E   V G+PTL    K  KN   +  Y+G R  D  +KY+  ++
Sbjct:  386 LIEFYAPWCGHCKKLSPIYEELAEKL--QDEDVAIVKMDATANDVPPE-FNVRGFPTLFWLPKDAKNKPVS--YNGGREVDDFLKYIAKEA 471

HSP 4 Score: 60.077 bits (144), Expect = 4.786e-9
Identity = 32/92 (34.78%), Postives = 51/92 (55.43%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDAT--ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
             L+ FYAPWCGHCK L P+Y + A+ +  +   I +AK+D T    +  S Y VSG+PT+    ++     + Y+  RE   + KY+ ++  
Sbjct:   42 TLVMFYAPWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQD--EVSQDYNGPREASGIAKYMRAQVG 131

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: Pdi (gene:FBgn0286818 transcript:FBtr0346644)

HSP 1 Score: 132.88 bits (333), Expect = 1.729e-32
Identity = 71/195 (36.41%), Postives = 113/195 (57.95%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVE 587
            ++  +LVEFYAPWCGHCK LAPEY  AA  L +++ PI +AKVD T E +  E++ V GYPTLK F++G    +YSG R A  II ++  K+GP +K+L +  +  +F    +  ++GFF    S+  K F  VA  L+  F F  + +  +  K   K+N V+     +   F+D +  ++G+ +E  ++ + +
Sbjct:   43 DNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGS-PVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDS-FVFGVSSNADVIAKYEAKDNGVV-----LFKPFDDKKSVFEGELNEENLKKFAQ 230

HSP 2 Score: 126.331 bits (316), Expect = 2.478e-30
Identity = 78/198 (39.39%), Postives = 124/198 (62.63%), Query Frame = 1

Query: 1546 KVAKKFIDSGKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFKMIAD-FSMENLEKFINDFLQEKVPVYLKSESIPEKNDE-PVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTI-YFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            ++AKK+ D    +   IS+ +E +  + E+ G+   +   + +   +E   K+K  +D  S E +E F+  FL  K+  +L S+ +PE  D+ PVKV+V+ NF+ +  D +K VL+EFYAPWCGHCK LAP Y++LA+K     DIVIAKMD+TAN++ S  ++S FPTI YF  +++K     ++  R +DD +K++
Sbjct:  277 EIAKKYRDD--ILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELES-IKISSFPTIKYFRKEDNK--VIDFNLDRTLDDFVKFL 469

HSP 3 Score: 92.8189 bits (229), Expect = 2.044e-19
Identity = 49/121 (40.50%), Postives = 74/121 (61.16%), Query Frame = 1

Query: 1804 KNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNF 2160
            K +E V V    NF +++ D  + VL+EFYAPWCGHCK+LAP+Y + A++L+  ES I +AK+DAT   ++   Y V G+PT+ F       SP  YS GR+  D++ ++  +   P K+ 
Sbjct:   24 KVEEGVLVATVDNFKQLIAD-NEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSG---SPVEYSGGRQAADIIAWVTKKTGPPAKDL 140

HSP 4 Score: 71.633 bits (174), Expect = 1.301e-12
Identity = 37/85 (43.53%), Postives = 52/85 (61.18%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFAFDYSGERSADGIIKYM 266
            +LVEFYAPWCGHCK+LAP Y+  A   K  +  I IAK+D TA     E   +S +PT+K F K      D++ +R+ D  +K++
Sbjct:  388 VLVEFYAPWCGHCKQLAPIYDQLAEKYKDNE-DIVIAKMDSTA--NELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFL 469

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: Pdi (gene:FBgn0286818 transcript:FBtr0075648)

HSP 1 Score: 132.88 bits (333), Expect = 1.729e-32
Identity = 71/195 (36.41%), Postives = 113/195 (57.95%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVE 587
            ++  +LVEFYAPWCGHCK LAPEY  AA  L +++ PI +AKVD T E +  E++ V GYPTLK F++G    +YSG R A  II ++  K+GP +K+L +  +  +F    +  ++GFF    S+  K F  VA  L+  F F  + +  +  K   K+N V+     +   F+D +  ++G+ +E  ++ + +
Sbjct:   43 DNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGS-PVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDS-FVFGVSSNADVIAKYEAKDNGVV-----LFKPFDDKKSVFEGELNEENLKKFAQ 230

HSP 2 Score: 126.331 bits (316), Expect = 2.478e-30
Identity = 78/198 (39.39%), Postives = 124/198 (62.63%), Query Frame = 1

Query: 1546 KVAKKFIDSGKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFKMIAD-FSMENLEKFINDFLQEKVPVYLKSESIPEKNDE-PVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTI-YFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            ++AKK+ D    +   IS+ +E +  + E+ G+   +   + +   +E   K+K  +D  S E +E F+  FL  K+  +L S+ +PE  D+ PVKV+V+ NF+ +  D +K VL+EFYAPWCGHCK LAP Y++LA+K     DIVIAKMD+TAN++ S  ++S FPTI YF  +++K     ++  R +DD +K++
Sbjct:  277 EIAKKYRDD--ILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELES-IKISSFPTIKYFRKEDNK--VIDFNLDRTLDDFVKFL 469

HSP 3 Score: 92.8189 bits (229), Expect = 2.044e-19
Identity = 49/121 (40.50%), Postives = 74/121 (61.16%), Query Frame = 1

Query: 1804 KNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNF 2160
            K +E V V    NF +++ D  + VL+EFYAPWCGHCK+LAP+Y + A++L+  ES I +AK+DAT   ++   Y V G+PT+ F       SP  YS GR+  D++ ++  +   P K+ 
Sbjct:   24 KVEEGVLVATVDNFKQLIAD-NEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSG---SPVEYSGGRQAADIIAWVTKKTGPPAKDL 140

HSP 4 Score: 71.633 bits (174), Expect = 1.301e-12
Identity = 37/85 (43.53%), Postives = 52/85 (61.18%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFAFDYSGERSADGIIKYM 266
            +LVEFYAPWCGHCK+LAP Y+  A   K  +  I IAK+D TA     E   +S +PT+K F K      D++ +R+ D  +K++
Sbjct:  388 VLVEFYAPWCGHCKQLAPIYDQLAEKYKDNE-DIVIAKMDSTA--NELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFL 469

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: CG9302 (gene:FBgn0032514 transcript:FBtr0080470)

HSP 1 Score: 88.5817 bits (218), Expect = 6.037e-18
Identity = 41/83 (49.40%), Postives = 55/83 (66.27%), Query Frame = 3

Query:   18 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYM 266
            LV FYAPWCGHCK++ PEYE AA  +K++  P  +A +D T E    EK+ V GYPT+K F NG F F+ +  R A  I+++M
Sbjct:  292 LVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSIAEKYKVKGYPTVKFFSNGVFKFEVN-VREASKIVEFM 373

HSP 2 Score: 88.1965 bits (217), Expect = 7.731e-18
Identity = 44/97 (45.36%), Postives = 56/97 (57.73%), Query Frame = 3

Query:   18 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTE 308
            LV FYAPWCGHCK   PE+  AATAL+  DP IA   +DCT     C K+ V GYPT+  F   +   DY+G R++   I YM   + P +   +TE
Sbjct:  417 LVMFYAPWCGHCKHTKPEFTAAATALQ-DDPRIAFVAIDCTKLAALCAKYNVRGYPTILYFSYLKTKLDYNGGRTSKDFIAYM---NNPPTSADRTE 509

HSP 3 Score: 71.633 bits (174), Expect = 1.315e-12
Identity = 37/98 (37.76%), Postives = 55/98 (56.12%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPI-AIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMV---SKSGPSSKE 296
            +LV FY PWCG CKK+ PEY  A+T LK +   I A   V+        +   ++G+PTL  F+NG+  F Y GE + + ++ +M+   +K  P  KE
Sbjct:  165 MLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYFENGKLRFTYEGENNKEALVSFMLNPNAKPTPKPKE 262

HSP 4 Score: 58.9214 bits (141), Expect = 1.074e-8
Identity = 33/94 (35.11%), Postives = 48/94 (51.06%), Query Frame = 1

Query: 1870 KDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDAT-ANDVPSPYEVSGFPTI-YFAPKNSKHSPKSYSSGREVDDMLKYIASEASS 2145
            K  L+ FYAPWCGHCK   P++   A  L  +  I    +D T    + + Y V G+PTI YF+   +K     Y+ GR   D + Y+ +  +S
Sbjct:  414 KHALVMFYAPWCGHCKHTKPEFTAAATALQDDPRIAFVAIDCTKLAALCAKYNVRGYPTILYFSYLKTKL---DYNGGRTSKDFIAYMNNPPTS 504

HSP 5 Score: 58.9214 bits (141), Expect = 1.300e-8
Identity = 28/77 (36.36%), Postives = 47/77 (61.04%), Query Frame = 1

Query: 1828 VVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATAN-DVPSPYEVSGFPTIYF 2052
            + ++ F+  + D  K  L+ FYAPWCGHCK + P+YE+ A ++  +    ++A +DAT    +   Y+V G+PT+ F
Sbjct:  276 LTSQGFEPALKD-EKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSIAEKYKVKGYPTVKF 351

HSP 6 Score: 52.373 bits (124), Expect = 1.420e-6
Identity = 28/97 (28.87%), Postives = 51/97 (52.58%), Query Frame = 1

Query: 1786 SESIPEKNDEPVKVVV----AKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAND---VPSPYEVSGFPT-IYF 2052
            S  +P + D   K V+    A +F + +    + +L+ FY PWCG CK + P+Y + + +L  +   ++A M+    +   +   + ++GFPT IYF
Sbjct:  131 SGDLPWEEDPAGKDVLHFSDAASFTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMFNITGFPTLIYF 227

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Match: prtp (gene:FBgn0030329 transcript:FBtr0332954)

HSP 1 Score: 84.7297 bits (208), Expect = 2.908e-17
Identity = 40/88 (45.45%), Postives = 52/88 (59.09%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTA--ETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYM 266
             V  ++FYAPWCGHC+KL P +E  AT   +    + IAKVDCTA    + C    V GYPTL ++KNGQ   +Y G RS   +  Y+
Sbjct:  257 GVAFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCTAPENKQVCIDQQVEGYPTLFLYKNGQRQNEYEGSRSLPELQAYL 344

HSP 2 Score: 73.1738 bits (178), Expect = 1.655e-13
Identity = 35/107 (32.71%), Postives = 58/107 (54.21%), Query Frame = 1

Query: 1867 TKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRK 2184
            T +  ++F+APWC HC+ LAP +E+LAK+L  E  + I+K+D T    +   +EV G+PT+ +     K   + YS  R++  +  Y+      PL+    +  D K
Sbjct:  119 TGNHFVKFFAPWCSHCQRLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQDFEVKGYPTLLWIEDGKK--IEKYSGARDLSTLKTYVEKMVGVPLEKTAGEAGDEK 223

HSP 3 Score: 72.7886 bits (177), Expect = 2.420e-13
Identity = 35/87 (40.23%), Postives = 50/87 (57.47%), Query Frame = 3

Query:   21 VEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSG 281
            V+F+APWC HC++LAP +E  A  L K +P + I+K+DCT     C+   V GYPTL   ++G+    YSG R    +  Y+    G
Sbjct:  124 VKFFAPWCSHCQRLAPTWEDLAKELIK-EPTVTISKIDCTQFRSICQDFEVKGYPTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVG 209

HSP 4 Score: 67.781 bits (164), Expect = 1.127e-11
Identity = 33/88 (37.50%), Postives = 50/88 (56.82%), Query Frame = 3

Query:   42 CGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG-QFAFDYSGERSADGIIKYMVSK-SGPSSKEL 299
            CGHCK++ P +E  A  +   +P + IAKVDCT     C  H V+GYPTL++FK G + +  + G R    I  ++  + S P+  +L
Sbjct:    2 CGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITDFINKELSAPAEADL 89

HSP 5 Score: 67.0106 bits (162), Expect = 1.688e-11
Identity = 42/137 (30.66%), Postives = 68/137 (49.64%), Query Frame = 1

Query: 1732 LEKFINDFLQEKVPVY-LKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATA---NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            LEK   +   EKV +  +  E    K   P ++     FD+ + +      I+FYAPWCGHC+ L P +E+LA +   A+S + IAK+D TA     V    +V G+PT++      + +   Y   R + ++  Y+
Sbjct:  212 LEKTAGEAGDEKVVIEEVAGEEDAAKKLTPQQLTGEDEFDQAIAEGV--AFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCTAPENKQVCIDQQVEGYPTLFLYKNGQRQN--EYEGSRSLPELQAYL 344

HSP 6 Score: 49.6766 bits (117), Expect = 7.530e-6
Identity = 25/84 (29.76%), Postives = 51/84 (60.71%), Query Frame = 1

Query: 1903 CGHCKSLAPKYEELAKKLSAES-DIVIAKMDATAND-VPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
            CGHCK + P +E+LA+ ++ ++  ++IAK+D T +  + + ++V+G+PT+       + S K +   R++  +  +I  E S+P
Sbjct:    2 CGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVK-FKGTRDLPAITDFINKELSAP 84

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia3 (protein disulfide isomerase family A, member 3 [Source:ZFIN;Acc:ZDB-GENE-031002-9])

HSP 1 Score: 286.96 bits (733), Expect = 1.985e-88
Identity = 134/248 (54.03%), Postives = 174/248 (70.16%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             G+  H T  N      + L+VA Y+VDYEKNPKG+NYWRNR++KVAK F+D GK + FA++N    + ++SE G++        +  R  +  K+ M  +FS +   LE+F+ D+    +  YLKSE +PE ND PVKV+VA+NFD IVND +KDVLIEFYAPWCGHCKSL PKY+EL +KLS + +IVIAKMDATANDVPSPYEVSGFPTIYF+P   K +PK Y  GREV D + Y+  EA++ +
Sbjct:  196 FGICAHMTEDNKDQLKGKDLLVAYYDVDYEKNPKGSNYWRNRVMKVAKGFLDQGKKLSFAVANKNRFSHDVSELGLDGSSGELPLVGIRTAKGDKYVMKEEFSRDGKALERFLQDYFDGNLKRYLKSEPVPENNDGPVKVLVAENFDSIVNDDSKDVLIEFYAPWCGHCKSLEPKYKELGEKLSEDPNIVIAKMDATANDVPSPYEVSGFPTIYFSPAGRKQNPKKYEGGREVSDFISYLKREATNTV 443

HSP 2 Score: 190.274 bits (482), Expect = 1.390e-52
Identity = 94/197 (47.72%), Postives = 131/197 (66.50%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDA-SEHQIRTWVEENM 596
            +ILVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA +K C K+GVSGYPTLK+F++G+ +  Y G R+ADGI+ ++  ++GP+S ELK E +F K+    D  VVGFF    S     FL  A  L E +RFAHT +E L  K       I++F S +++NKFED+ V +  D  +  +I+ ++++N+
Sbjct:    2 LILVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANSKVCGKYGVSGYPTLKIFRDGEDSGGYDGPRTADGIVSHLKKQAGPASVELKNEADFEKYIGDRDASVVGFFADGGSAAQGEFLKAASALRESYRFAHTNNEDLLKKHGIDGEGIILFRSPQLSNKFEDSSVLFTEDKFTSAKIKKFIQDNI 195

HSP 3 Score: 71.633 bits (174), Expect = 1.347e-12
Identity = 47/127 (37.01%), Postives = 68/127 (53.54%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAND-VPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLKN---FDRQGRDRKSDL*KF*FIEIKSSLTG 2235
            +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN  V   Y VSG+PT+             Y   R  D ++ ++   A  AS  LKN   F++   DR + +  F F +  S+  G
Sbjct:    3 ILVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANSKVCGKYGVSGYPTLKIF--RDGEDSGGYDGPRTADGIVSHLKKQAGPASVELKNEADFEKYIGDRDASVVGF-FADGGSAAQG 124

HSP 4 Score: 67.3958 bits (163), Expect = 2.926e-11
Identity = 37/86 (43.02%), Postives = 47/86 (54.65%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYM 266
            +L+EFYAPWCGHCK L P+Y+     L  +DP I IAK+D TA       + VSG+PT+     G  Q    Y G R     I Y+
Sbjct:  352 VLIEFYAPWCGHCKSLEPKYKELGEKL-SEDPNIVIAKMDATA-NDVPSPYEVSGFPTIYFSPAGRKQNPKKYEGGREVSDFISYL 435

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia7 (protein disulfide isomerase family A, member 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2238])

HSP 1 Score: 273.863 bits (699), Expect = 5.200e-83
Identity = 133/250 (53.20%), Postives = 171/250 (68.40%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            +GL  H T  N     +  L+ A +NVDY +NPKGTNYWRNRI+KVA +F D G  + FA+++ QE   EL E +G+ S +   V  +T R    QK+ M  +F+ +   LEKF+ D+  +++  Y+KSE IPE ND PVKV+VA  FD IVNDP KDVL+EFYAPWCGHCK+L PKY+EL +KLS   +IVIAKMDATANDVP  Y+V GFPTIYF P   K  P+ Y  GREV+D + Y+  EA++PL
Sbjct:  232 LGLCPHMTMENRDTVRESDLLTAFFNVDYLRNPKGTNYWRNRIMKVATQFQDRG--LTFAVADRQEFQDELEEEFGVSSSEGGDVPLVTIRTRAGQKYSMQEEFTRDGKSLEKFLEDYFAKRLKRYVKSEPIPESNDGPVKVLVADTFDAIVNDPEKDVLVEFYAPWCGHCKNLEPKYKELGEKLSGNPNIVIAKMDATANDVPPNYDVQGFPTIYFVPSGQKDQPRRYEGGREVNDFITYLKKEATNPL 479

HSP 2 Score: 181.415 bits (459), Expect = 3.973e-49
Identity = 87/198 (43.94%), Postives = 126/198 (63.64%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN-IVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            H  +LVEF+APWCGHC++LAPEYE AAT LK     +A+AKVDCT  ++TCE+ GV+GYPTLK+F+NG+ +  Y G R+ADGI+ YM  ++GPSS  L  E + + F  + +  VVGFF+ E S     FL  +  L + +RFAH+ D     K       +++F   ++++KFED  VKY    S   +  +V++N+
Sbjct:   37 HDTLLVEFFAPWCGHCQRLAPEYEAAATKLKGT---LALAKVDCTVNSETCERFGVNGYPTLKIFRNGEESGAYDGPRTADGIVSYMKKQAGPSSVALLKEADLDGFVDNYEASVVGFFSGEDSAQLAEFLKASSALRDSYRFAHSTDVGAGLKYGVDGECVLLFRPPRLSSKFEDNVVKYTEHLSVSSLHKFVKDNI 231

HSP 3 Score: 68.5514 bits (166), Expect = 1.525e-11
Identity = 34/90 (37.78%), Postives = 54/90 (60.00%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EF+APWCGHC+ LAP+YE  A KL     + +AK+D T N +    + V+G+PT+    +N + S  +Y   R  D ++ Y+  +A 
Sbjct:   40 LLVEFFAPWCGHCQRLAPEYEAAATKLKGT--LALAKVDCTVNSETCERFGVNGYPTLKIF-RNGEES-GAYDGPRTADGIVSYMKKQAG 125

HSP 4 Score: 66.6254 bits (161), Expect = 6.263e-11
Identity = 36/86 (41.86%), Postives = 47/86 (54.65%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQ--FAFDYSGERSADGIIKYM 266
            +LVEFYAPWCGHCK L P+Y+     L   +P I IAK+D TA       + V G+PT+    +GQ      Y G R  +  I Y+
Sbjct:  388 VLVEFYAPWCGHCKNLEPKYKELGEKLSG-NPNIVIAKMDATA-NDVPPNYDVQGFPTIYFVPSGQKDQPRRYEGGREVNDFITYL 471

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia8 (protein disulfide isomerase family A, member 8 [Source:ZFIN;Acc:ZDB-GENE-040801-20])

HSP 1 Score: 244.973 bits (624), Expect = 3.123e-72
Identity = 121/250 (48.40%), Postives = 164/250 (65.60%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             GL  H T  N +   KR L+ A Y++DY  NPKG+NYWRNR+LKVA KF  S + + F+++N  +  +EL E +G+ + D +++ ++T R     K+ M  +F+ +   LE F+ D+   ++  Y+KSE +P  N+  VKVVVA  F+EIVNDP KDVLIEFYAPWCGHCK L PKY  L + L ++ +IVIAKMDAT NDVP+ Y+V GFPTIYFA    K  PK Y   REV D + ++  EA+ PL
Sbjct:  238 FGLCPHMTKDNKEVLRKRDLLTAYYDLDYLHNPKGSNYWRNRVLKVATKF--SSQGMLFSVANRNDFMEELEEEFGLSASDGNELPFVTIRTRTGDKYSMREEFTRDGKSLESFLEDYFAGRLKRYVKSEPVPAINNGVVKVVVADTFEEIVNDPEKDVLIEFYAPWCGHCKKLEPKYTALGEMLYSDPNIVIAKMDATVNDVPAGYDVQGFPTIYFAAAGRKSEPKRYEGAREVKDFVNFLKREATKPL 485

HSP 2 Score: 184.496 bits (467), Expect = 3.795e-50
Identity = 90/199 (45.23%), Postives = 127/199 (63.82%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EH  +LV+FYAPWCGHCKKLAPE+E AA+ LK     + +AKVDCTA T+ C+ +GV+GYPTLK+F+NG  +  Y G RSADGI+ YM  ++GP S  L +E +  KF    D  VVG F+   S     FL  A  + E FRFAHT D  L  K    + +I++F + ++++KFE++ V + G  S   +R ++ +N+
Sbjct:   42 EHETLLVKFYAPWCGHCKKLAPEFESAASRLKGT---VTLAKVDCTANTEICKHYGVNGYPTLKIFRNGHESSSYDGPRSADGIVDYMKKQAGPDSVLLHSELDLEKFINHFDASVVGLFSGTDSSQLAEFLKGASLMRESFRFAHTTDLQLGQKYGVTHESILLFRAPRLSSKFEESVVPHTGSLSVTGLRRFIRDNI 237

HSP 3 Score: 74.3294 bits (181), Expect = 2.199e-13
Identity = 35/90 (38.89%), Postives = 55/90 (61.11%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L++FYAPWCGHCK LAP++E  A +L  +  + +AK+D TAN ++   Y V+G+PT+      + H   SY   R  D ++ Y+  +A 
Sbjct:   46 LLVKFYAPWCGHCKKLAPEFESAASRL--KGTVTLAKVDCTANTEICKHYGVNGYPTLKIF--RNGHESSSYDGPRSADGIVDYMKKQAG 131

HSP 4 Score: 62.7734 bits (151), Expect = 9.257e-10
Identity = 29/59 (49.15%), Postives = 37/59 (62.71%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCKKL P+Y  A   +   DP I IAK+D T        + V G+PT+
Sbjct:  394 VLIEFYAPWCGHCKKLEPKY-TALGEMLYSDPNIVIAKMDATV-NDVPAGYDVQGFPTI 450

[Close]

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             GL  H T  N +   KR L+ A Y++DY  NPKG+NYWRNR+LKVA KF  S + + F+++N  +  +EL E +G+ + D +++ ++T R     K+ M  +F+ +   LE F+ D+   ++  Y+KSE +P  N+  VKVVVA  F+EIVNDP KDVLIEFYAPWCGHCK L PKY  L + L ++ +IVIAKMDAT NDVP+ Y+V GFPTIYFA    K  PK Y   REV D + ++  EA+ PL
Sbjct:  238 FGLCPHMTKDNKEVLRKRDLLTAYYDLDYLHNPKGSNYWRNRVLKVATKF--SSQGMLFSVANRNDFMEELEEEFGLSASDGNELPFVTIRTRTGDKYSMREEFTRDGKSLESFLEDYFAGRLKRYVKSEPVPAINNGVVKVVVADTFEEIVNDPEKDVLIEFYAPWCGHCKKLEPKYTALGEMLYSDPNIVIAKMDATVNDVPAGYDVQGFPTIYFAAAGRKSEPKRYEGAREVKDFVNFLKREATKPL 485

HSP 2 Score: 184.496 bits (467), Expect = 3.795e-50
Identity = 90/199 (45.23%), Postives = 127/199 (63.82%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EH  +LV+FYAPWCGHCKKLAPE+E AA+ LK     + +AKVDCTA T+ C+ +GV+GYPTLK+F+NG  +  Y G RSADGI+ YM  ++GP S  L +E +  KF    D  VVG F+   S     FL  A  + E FRFAHT D  L  K    + +I++F + ++++KFE++ V + G  S   +R ++ +N+
Sbjct:   42 EHETLLVKFYAPWCGHCKKLAPEFESAASRLKGT---VTLAKVDCTANTEICKHYGVNGYPTLKIFRNGHESSSYDGPRSADGIVDYMKKQAGPDSVLLHSELDLEKFINHFDASVVGLFSGTDSSQLAEFLKGASLMRESFRFAHTTDLQLGQKYGVTHESILLFRAPRLSSKFEESVVPHTGSLSVTGLRRFIRDNI 237

HSP 3 Score: 74.3294 bits (181), Expect = 2.199e-13
Identity = 35/90 (38.89%), Postives = 55/90 (61.11%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L++FYAPWCGHCK LAP++E  A +L  +  + +AK+D TAN ++   Y V+G+PT+      + H   SY   R  D ++ Y+  +A 
Sbjct:   46 LLVKFYAPWCGHCKKLAPEFESAASRL--KGTVTLAKVDCTANTEICKHYGVNGYPTLKIF--RNGHESSSYDGPRSADGIVDYMKKQAG 131

HSP 4 Score: 62.7734 bits (151), Expect = 9.257e-10
Identity = 29/59 (49.15%), Postives = 37/59 (62.71%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCKKL P+Y  A   +   DP I IAK+D T        + V G+PT+
Sbjct:  394 VLIEFYAPWCGHCKKLEPKY-TALGEMLYSDPNIVIAKMDATV-NDVPAGYDVQGFPTI 450

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Match: pdia4 (protein disulfide isomerase family A, member 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5493])

HSP 1 Score: 195.282 bits (495), Expect = 7.080e-53
Identity = 111/248 (44.76%), Postives = 153/248 (61.69%), Query Frame = 1

Query: 1414 MGLAGHRTHSN-VKYFAKRPLIVALYNVDYEKNPK-GTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKM-IADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVP-SPYEVSGFPTIYFAPKNSKHSPKSYSSG-REVDDMLKYIASEAS 2142
            + L GHR  SN  K + KRPL+V  Y VD+  + +  T +WR+++L+VAK F +      FAI++ ++   EL   G+ S    +V +    E  +K+ M   +F  + L  F+  F + K+   +KS+ +P+ N  PVKVVV K FDEIV D  KDVLIEFYAPWCGHCK L P Y  L KK   E ++VIAKMDATANDVP   Y+V GFPTIYFAP N+K +P  +  G R+V++  K++   A+
Sbjct:  391 LPLVGHRKQSNDAKRYTKRPLVVVYYGVDFSFDYRVATQFWRSKVLEVAKDFPE----YTFAIADEEDYADELKSLGL-SESGEEVNVGIVGEGGKKYAMEPEEFDSDVLRSFVMAFKKGKLKPIVKSQPLPKNNKGPVKVVVGKTFDEIVMDSKKDVLIEFYAPWCGHCKKLEPDYISLGKKYKNEKNLVIAKMDATANDVPHDSYKVEGFPTIYFAPSNNKQNPIKFEGGKRDVEEFSKFVEKHAT 633

HSP 2 Score: 162.155 bits (409), Expect = 2.067e-41
Identity = 78/174 (44.83%), Postives = 111/174 (63.79%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASA-DPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYK-NNIVIFHSKKMANKFE 527
            +ILVEFYAPWCGHCK+LAPEYE AA  L  + PPI +AKVD TAE+    + GVSGYPTLK+F+ G+ AFDY+G R   GI+ YM  ++GP SK+++T +   +      D V+VG F+S+    Y+ +      L ED++F HTF+  ++  L      +V+   +K  +K+E
Sbjct:  193 IILVEFYAPWCGHCKRLAPEYEKAAKELSNRTPPIPLAKVDATAESDLATRFGVSGYPTLKIFRKGK-AFDYNGPREKFGIVDYMSDQAGPPSKQVQTLKQVQELLRDGDDAVIVGVFSSDEDAAYEIYQEACNSLREDYKFMHTFNNDVTKFLKASPGQVVMLQPEKFRSKYE 365

HSP 3 Score: 112.079 bits (279), Expect = 4.606e-25
Identity = 54/122 (44.26%), Postives = 76/122 (62.30%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVS------KSGPSSKELKTEENFNKFTASADPVVVGFF 362
            +LVEFYAPWCGHCK+ APEYE  A  LK+ DPPI +AKVD T  +    +  VSGYPT+K+ K G+   DY G+RS   I++ +        K  P +  + T++NF+    +AD ++V F+
Sbjct:   79 VLVEFYAPWCGHCKQFAPEYEKIAQTLKENDPPIPVAKVDATKASGLGSRFEVSGYPTIKILKKGE-PLDYDGDRSEHAIVERVKEVAQPDWKPPPEATLVLTKDNFDDVVNNADIILVEFY 199

HSP 4 Score: 86.6557 bits (213), Expect = 4.524e-17
Identity = 49/117 (41.88%), Postives = 73/117 (62.39%), Query Frame = 1

Query: 1813 EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKN 2157
            E   V+   NFD++VN+    +L+EFYAPWCGHCK LAP+YE+ AK+LS  +  I +AK+DATA +D+ + + VSG+PT+    K        Y+  RE   ++ Y++ +A  P K 
Sbjct:  174 EATLVLTKDNFDDVVNN-ADIILVEFYAPWCGHCKRLAPEYEKAAKELSNRTPPIPLAKVDATAESDLATRFGVSGYPTLKIFRKGKAF---DYNGPREKFGIVDYMSDQAGPPSKQ 286

HSP 5 Score: 76.6406 bits (187), Expect = 5.693e-14
Identity = 48/103 (46.60%), Postives = 63/103 (61.17%), Query Frame = 1

Query: 1804 KNDEPVKVVVAKNFDEIVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKLSAESD--IVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGR 2100
            K +  V V+   NFD  +    KD VL+EFYAPWCGHCK  AP+YE++A+ L  E+D  I +AK+DAT A+ + S +EVSG+PTI    K     P  Y   R
Sbjct:   56 KEENGVLVLTDANFDTFIE--GKDTVLVEFYAPWCGHCKQFAPEYEKIAQTLK-ENDPPIPVAKVDATKASGLGSRFEVSGYPTIKILKKG---EPLDYDGDR 152

HSP 6 Score: 62.7734 bits (151), Expect = 1.203e-9
Identity = 28/59 (47.46%), Postives = 39/59 (66.10%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCKKL P+Y I+     K +  + IAK+D TA     + + V G+PT+
Sbjct:  543 VLIEFYAPWCGHCKKLEPDY-ISLGKKYKNEKNLVIAKMDATANDVPHDSYKVEGFPTI 600

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:394954])

HSP 1 Score: 291.197 bits (744), Expect = 2.996e-89
Identity = 136/247 (55.06%), Postives = 177/247 (71.66%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             GL  H T  N      + L+VA Y+VDYEKN KGTNYWRNR++KVAK F+D+GK ++FA++N +    E++E+G+++       +  +  + +K+ M  +FS +   LE+F+ D+   K+  Y+KSE+IPE ND PVKVVVA+NFDEIVND +KDVLIEFYAPWCGHCK+L PKY+EL +KL  + +IVIAKMDATANDVPS YEV GFPTIYF P  SK  PK Y  GREV D L Y+  EA++P
Sbjct:  237 FGLCPHLTEDNKDLIQGKDLLVAYYDVDYEKNVKGTNYWRNRVMKVAKSFVDAGKKLNFAVANRKAFGHEVTEFGLDAGTGELPVVGIKTAKGEKYAMQEEFSRDGKALERFLQDYFDGKLKRYMKSEAIPESNDGPVKVVVAENFDEIVNDDSKDVLIEFYAPWCGHCKNLEPKYKELGEKLGDDPNIVIAKMDATANDVPSQYEVRGFPTIYFTPAGSKQKPKRYEGGREVSDFLSYLKKEATNP 483

HSP 2 Score: 192.971 bits (489), Expect = 5.273e-53
Identity = 93/201 (46.27%), Postives = 136/201 (67.66%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGD--ASEHQIRTWVEENM 596
            +HS++LVEF+APWCGHCKKLAPEYEIAAT LK     +++AKVDCTA + TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+  M  ++GP+S +L++   F KF +  D  VVGFF    S  +  FL  A  L +++RFAHT ++ L  K +      V+F  + +ANKFED+ V +  D   +  +I+ ++++N+
Sbjct:   39 QHSILLVEFFAPWCGHCKKLAPEYEIAATKLKGT---LSLAKVDCTANSNTCNKYGVSGYPTLKIFRDGEDSGSYDGPRTADGIVSTMKKQAGPASVDLRSVGEFEKFISDKDASVVGFFRDLYSGPHSEFLKAANTLRDNYRFAHTDEKELVDKYDSNGEGFVLFRPQHLANKFEDSSVTFPADEKITSSKIKKFIQDNI 236

HSP 3 Score: 68.9366 bits (167), Expect = 1.453e-11
Identity = 39/102 (38.24%), Postives = 58/102 (56.86%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NF+  V+  +  +L+EF+APWCGHCK LAP+YE  A KL  +  + +AK+D TAN +  + Y VSG+PT+            SY   R  D ++  +  +A 
Sbjct:   32 NFESTVSQHSI-LLVEFFAPWCGHCKKLAPEYEIAATKL--KGTLSLAKVDCTANSNTCNKYGVSGYPTLKIF--RDGEDSGSYDGPRTADGIVSTMKKQAG 128

HSP 4 Score: 65.0846 bits (157), Expect = 2.729e-10
Identity = 35/86 (40.70%), Postives = 46/86 (53.49%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYM 266
            +L+EFYAPWCGHCK L P+Y+     L   DP I IAK+D TA      ++ V G+PT+     G  Q    Y G R     + Y+
Sbjct:  393 VLIEFYAPWCGHCKNLEPKYKELGEKL-GDDPNIVIAKMDATA-NDVPSQYEVRGFPTIYFTPAGSKQKPKRYEGGREVSDFLSYL 476

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:394954])

HSP 1 Score: 271.166 bits (692), Expect = 5.384e-83
Identity = 127/230 (55.22%), Postives = 165/230 (71.74%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSG 2097
             GL  H T  N      + L+VA Y+VDYEKN KGTNYWRNR++KVAK F+D+GK ++FA++N +    E++E+G+++       +  +  + +K+ M  +FS +   LE+F+ D+   K+  Y+KSE+IPE ND PVKVVVA+NFDEIVND +KDVLIEFYAPWCGHCK+L PKY+EL +KL  + +IVIAKMDATANDVPS YEV GFPTIYF P  SK  PK Y  G
Sbjct:  163 FGLCPHLTEDNKDLIQGKDLLVAYYDVDYEKNVKGTNYWRNRVMKVAKSFVDAGKKLNFAVANRKAFGHEVTEFGLDAGTGELPVVGIKTAKGEKYAMQEEFSRDGKALERFLQDYFDGKLKRYMKSEAIPESNDGPVKVVVAENFDEIVNDDSKDVLIEFYAPWCGHCKNLEPKYKELGEKLGDDPNIVIAKMDATANDVPSQYEVRGFPTIYFTPAGSKQKPKRYEVG 392

HSP 2 Score: 147.132 bits (370), Expect = 1.082e-37
Identity = 72/144 (50.00%), Postives = 98/144 (68.06%), Query Frame = 3

Query:   42 CGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLN 473
            CGHCKKLAPEYEIAAT LK     +++AKVDCTA + TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+  M  ++GP+S +L++   F KF +  D  VVGFF    S  +  FL  A  L +++RFAHT ++ L  K +
Sbjct:   18 CGHCKKLAPEYEIAATKLKGT---LSLAKVDCTANSNTCNKYGVSGYPTLKIFRDGEDSGSYDGPRTADGIVSTMKKQAGPASVDLRSVGEFEKFISDKDASVVGFFRDLYSGPHSEFLKAANTLRDNYRFAHTDEKELVDKYD 158

HSP 3 Score: 62.3882 bits (150), Expect = 1.410e-9
Identity = 29/59 (49.15%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK L P+Y+     L   DP I IAK+D TA      ++ V G+PT+
Sbjct:  319 VLIEFYAPWCGHCKNLEPKYKELGEKL-GDDPNIVIAKMDATA-NDVPSQYEVRGFPTI 375

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:394954])

HSP 1 Score: 271.166 bits (692), Expect = 1.566e-82
Identity = 127/230 (55.22%), Postives = 165/230 (71.74%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSG 2097
             GL  H T  N      + L+VA Y+VDYEKN KGTNYWRNR++KVAK F+D+GK ++FA++N +    E++E+G+++       +  +  + +K+ M  +FS +   LE+F+ D+   K+  Y+KSE+IPE ND PVKVVVA+NFDEIVND +KDVLIEFYAPWCGHCK+L PKY+EL +KL  + +IVIAKMDATANDVPS YEV GFPTIYF P  SK  PK Y  G
Sbjct:  191 FGLCPHLTEDNKDLIQGKDLLVAYYDVDYEKNVKGTNYWRNRVMKVAKSFVDAGKKLNFAVANRKAFGHEVTEFGLDAGTGELPVVGIKTAKGEKYAMQEEFSRDGKALERFLQDYFDGKLKRYMKSEAIPESNDGPVKVVVAENFDEIVNDDSKDVLIEFYAPWCGHCKNLEPKYKELGEKLGDDPNIVIAKMDATANDVPSQYEVRGFPTIYFTPAGSKQKPKRYEVG 420

HSP 2 Score: 167.162 bits (422), Expect = 2.295e-44
Identity = 84/188 (44.68%), Postives = 123/188 (65.43%), Query Frame = 3

Query:   42 CGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGD--ASEHQIRTWVEENM 596
            CGHCKKLAPEYEIAAT LK     +++AKVDCTA + TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+  M  ++GP+S +L++   F KF +  D  VVGFF    S  +  FL  A  L +++RFAHT ++ L  K +      V+F  + +ANKFED+ V +  D   +  +I+ ++++N+
Sbjct:    6 CGHCKKLAPEYEIAATKLKGT---LSLAKVDCTANSNTCNKYGVSGYPTLKIFRDGEDSGSYDGPRTADGIVSTMKKQAGPASVDLRSVGEFEKFISDKDASVVGFFRDLYSGPHSEFLKAANTLRDNYRFAHTDEKELVDKYDSNGEGFVLFRPQHLANKFEDSSVTFPADEKITSSKIKKFIQDNI 190

HSP 3 Score: 62.7734 bits (151), Expect = 1.181e-9
Identity = 29/59 (49.15%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK L P+Y+     L   DP I IAK+D TA      ++ V G+PT+
Sbjct:  347 VLIEFYAPWCGHCKNLEPKYKELGEKL-GDDPNIVIAKMDATA-NDVPSQYEVRGFPTI 403

HSP 4 Score: 50.447 bits (119), Expect = 8.379e-6
Identity = 30/81 (37.04%), Postives = 42/81 (51.85%), Query Frame = 1

Query: 1903 CGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            CGHCK LAP+YE  A KL     + +AK+D TAN +  + Y VSG+PT+            SY   R  D ++  +  +A 
Sbjct:    6 CGHCKKLAPEYEIAATKLKGT--LSLAKVDCTANSNTCNKYGVSGYPTLKIF--RDGEDSGSYDGPRTADGIVSTMKKQAG 82

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:394954])

HSP 1 Score: 248.825 bits (634), Expect = 1.441e-73
Identity = 122/247 (49.39%), Postives = 163/247 (65.99%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             GL  H T  N      + L+VA Y+VDYEKN KGTNYWRNR++KVAK F+D+GK ++FA++N +    E++E+G+++       +  +  + +K+ M  +FS +   LE+F+ D+   K+  Y+KSE+IPE ND PVKVVVA+NFDEIVND +KDVLIEFYAPWCGHCK+L PKY+EL +KL  + +IVIAKMDATANDVPS YE                       GREV D L Y+  EA++P
Sbjct:  237 FGLCPHLTEDNKDLIQGKDLLVAYYDVDYEKNVKGTNYWRNRVMKVAKSFVDAGKKLNFAVANRKAFGHEVTEFGLDAGTGELPVVGIKTAKGEKYAMQEEFSRDGKALERFLQDYFDGKLKRYMKSEAIPESNDGPVKVVVAENFDEIVNDDSKDVLIEFYAPWCGHCKNLEPKYKELGEKLGDDPNIVIAKMDATANDVPSQYE----------------------GGREVSDFLSYLKKEATNP 461

HSP 2 Score: 192.971 bits (489), Expect = 3.861e-53
Identity = 93/201 (46.27%), Postives = 136/201 (67.66%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGD--ASEHQIRTWVEENM 596
            +HS++LVEF+APWCGHCKKLAPEYEIAAT LK     +++AKVDCTA + TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+  M  ++GP+S +L++   F KF +  D  VVGFF    S  +  FL  A  L +++RFAHT ++ L  K +      V+F  + +ANKFED+ V +  D   +  +I+ ++++N+
Sbjct:   39 QHSILLVEFFAPWCGHCKKLAPEYEIAATKLKGT---LSLAKVDCTANSNTCNKYGVSGYPTLKIFRDGEDSGSYDGPRTADGIVSTMKKQAGPASVDLRSVGEFEKFISDKDASVVGFFRDLYSGPHSEFLKAANTLRDNYRFAHTDEKELVDKYDSNGEGFVLFRPQHLANKFEDSSVTFPADEKITSSKIKKFIQDNI 236

HSP 3 Score: 69.3218 bits (168), Expect = 1.223e-11
Identity = 39/102 (38.24%), Postives = 57/102 (55.88%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NF+  V+  +  +L+EF+APWCGHCK LAP+YE  A KL     + +AK+D TAN +  + Y VSG+PT+            SY   R  D ++  +  +A 
Sbjct:   32 NFESTVSQHSI-LLVEFFAPWCGHCKKLAPEYEIAATKLKGT--LSLAKVDCTANSNTCNKYGVSGYPTLKIF--RDGEDSGSYDGPRTADGIVSTMKKQAG 128

HSP 4 Score: 58.5362 bits (140), Expect = 2.561e-8
Identity = 25/43 (58.14%), Postives = 30/43 (69.77%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTA 143
            +L+EFYAPWCGHCK L P+Y+     L   DP I IAK+D TA
Sbjct:  393 VLIEFYAPWCGHCKNLEPKYKELGEKL-GDDPNIVIAKMDATA 434

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:394954])

HSP 1 Score: 243.047 bits (619), Expect = 5.098e-72
Identity = 114/209 (54.55%), Postives = 152/209 (72.73%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSG 2034
             GL  H T  N      + L+VA Y+VDYEKN KGTNYWRNR++KVAK F+D+GK ++FA++N +    E++E+G+++       +  +  + +K+ M  +FS +   LE+F+ D+   K+  Y+KSE+IPE ND PVKVVVA+NFDEIVND +KDVLIEFYAPWCGHCK+L PKY+EL +KL  + +IVIAKMDATANDVPS YEV G
Sbjct:  227 FGLCPHLTEDNKDLIQGKDLLVAYYDVDYEKNVKGTNYWRNRVMKVAKSFVDAGKKLNFAVANRKAFGHEVTEFGLDAGTGELPVVGIKTAKGEKYAMQEEFSRDGKALERFLQDYFDGKLKRYMKSEAIPESNDGPVKVVVAENFDEIVNDDSKDVLIEFYAPWCGHCKNLEPKYKELGEKLGDDPNIVIAKMDATANDVPSQYEVRG 435

HSP 2 Score: 192.971 bits (489), Expect = 1.537e-53
Identity = 93/201 (46.27%), Postives = 136/201 (67.66%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGD--ASEHQIRTWVEENM 596
            +HS++LVEF+APWCGHCKKLAPEYEIAAT LK     +++AKVDCTA + TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+  M  ++GP+S +L++   F KF +  D  VVGFF    S  +  FL  A  L +++RFAHT ++ L  K +      V+F  + +ANKFED+ V +  D   +  +I+ ++++N+
Sbjct:   29 QHSILLVEFFAPWCGHCKKLAPEYEIAATKLKGT---LSLAKVDCTANSNTCNKYGVSGYPTLKIFRDGEDSGSYDGPRTADGIVSTMKKQAGPASVDLRSVGEFEKFISDKDASVVGFFRDLYSGPHSEFLKAANTLRDNYRFAHTDEKELVDKYDSNGEGFVLFRPQHLANKFEDSSVTFPADEKITSSKIKKFIQDNI 226

HSP 3 Score: 70.8626 bits (172), Expect = 3.237e-12
Identity = 43/118 (36.44%), Postives = 65/118 (55.08%), Query Frame = 1

Query: 1792 SIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            S+P ++D  V  +   NF+  V+  +  +L+EF+APWCGHCK LAP+YE  A KL     + +AK+D TAN +  + Y VSG+PT+            SY   R  D ++  +  +A 
Sbjct:    8 SLPARSD--VLDLTDDNFESTVSQHSI-LLVEFFAPWCGHCKKLAPEYEIAATKLKGT--LSLAKVDCTANSNTCNKYGVSGYPTLKIF--RDGEDSGSYDGPRTADGIVSTMKKQAG 118

HSP 4 Score: 58.5362 bits (140), Expect = 2.243e-8
Identity = 25/43 (58.14%), Postives = 30/43 (69.77%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTA 143
            +L+EFYAPWCGHCK L P+Y+     L   DP I IAK+D TA
Sbjct:  383 VLIEFYAPWCGHCKNLEPKYKELGEKL-GDDPNIVIAKMDATA 424

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia3 (protein disulfide isomerase associated 3 [Source:MGI Symbol;Acc:MGI:95834])

HSP 1 Score: 283.878 bits (725), Expect = 1.312e-86
Identity = 133/247 (53.85%), Postives = 178/247 (72.06%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             GL  H T  N      + L+ A Y+VDYEKN KG+NYWRNR++ VAKKF+D+G  ++FA+++ +  + ELS++G+ES       +  R  + +KF M  +FS +   LE+F+ ++    +  YLKSE IPE N+ PVKVVVA+NFD+IVN+  KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y  GRE++D + Y+  EA++P
Sbjct:  241 FGLCPHMTEDNKDLIQGKDLLTAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTTGEVPVVAIRTAKGEKFVMQEEFSRDGKALEQFLQEYFDGNLKRYLKSEPIPESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREATNP 487

HSP 2 Score: 188.348 bits (477), Expect = 2.219e-51
Identity = 96/182 (52.75%), Postives = 123/182 (67.58%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN---IVIFHSKKMANKFEDTQVKY 545
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ A  Y G R+ADGI+ ++  ++GP+S  L+TEE F KF +  D  VVGFF    SD +  FL  A  L +++RFAHT  E+L  +  Y +N   I IF    +ANKFED  V Y
Sbjct:   46 GLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASVVGFFRDLFSDGHSEFLKAASNLRDNYRFAHTNIESLVKE--YDDNGEGITIFRPLHLANKFEDKTVAY 222

HSP 3 Score: 70.8626 bits (172), Expect = 2.684e-12
Identity = 42/113 (37.17%), Postives = 65/113 (57.52%), Query Frame = 1

Query: 1837 KNFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLKN 2157
            +NF+  V+D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++   A  AS PL+ 
Sbjct:   33 ENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQAGPASVPLRT 141

HSP 4 Score: 63.929 bits (154), Expect = 4.515e-10
Identity = 31/63 (49.21%), Postives = 39/63 (61.90%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            E   +L+EFYAPWCGHCK L P+Y+     L K DP I IAK+D TA       + V G+PT+
Sbjct:  393 EDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKMDATA-NDVPSPYEVKGFPTI 453

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia4 (protein disulfide isomerase associated 4 [Source:MGI Symbol;Acc:MGI:104864])

HSP 1 Score: 198.749 bits (504), Expect = 4.947e-54
Identity = 110/249 (44.18%), Postives = 155/249 (62.25%), Query Frame = 1

Query: 1411 SMGLAGHRTHSN-VKYFAKRPLIVALYNVDYEKNPKG-TNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKM-IADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPS-PYEVSGFPTIYFAPKNSKHSPKSYSSG-REVDDMLKYIASEAS 2142
            ++ L GHR  SN  K ++KRPL+V  Y+VD+  + +  T +WRN++L+VAK F +      FAI++ ++   E+ + G+ S     V     DE  +KF M   +F  + L +F+  F + K+   +KS+ +P+ N  PVKVVV K FD IV DP KDVLIEFYAPWCGHCK L P Y  L KK   + D+VIAKMDATAND+ +  Y+V GFPTIYFAP   K +P  +  G R+++ + K+I   A+
Sbjct:  389 ALPLVGHRKTSNDAKRYSKRPLVVVYYSVDFSFDYRAATQFWRNKVLEVAKDFPE----YTFAIADEEDYATEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHAT 632

HSP 2 Score: 164.851 bits (416), Expect = 2.366e-42
Identity = 81/174 (46.55%), Postives = 109/174 (62.64%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVV-VGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYK-NNIVIFHSKKMANKFE 527
            +ILVEFYAPWCGHCKKLAPEYE AA  L K+ PPI +AKVD T +T   ++  VSGYPTLK+F+ G+  FDY+G R   GI+ YM+ +SGP SKE+ T +   +F    D VV +G F  +    Y  +   A  L ED++F HTF   ++  L      +V+ H +K  +K+E
Sbjct:  192 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLAKRFDVSGYPTLKIFRKGR-PFDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVVIIGLFQGDGDPAYLQYQDAANNLREDYKFHHTFSPEIAKFLKVSLGKLVLTHPEKFQSKYE 364

HSP 3 Score: 113.62 bits (283), Expect = 1.587e-25
Identity = 56/126 (44.44%), Postives = 79/126 (62.70%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPS---SKELK---TEENFNKFTASADPVVVGFF 362
            +   +L+EFYAPWCGHCK+ APEYE  A+ LK  DPPIA+AK+D T+ +    K  VSGYPT+K+ K GQ A DY G R+ + I+  +   S P      E+    T++NF+    +AD ++V F+
Sbjct:   74 DKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTIKILKKGQ-AVDYDGSRTQEEIVAKVREVSQPDWTPPPEVTLSLTKDNFDDVVNNADIILVEFY 198

HSP 4 Score: 85.5001 bits (210), Expect = 1.151e-16
Identity = 54/136 (39.71%), Postives = 82/136 (60.29%), Query Frame = 1

Query: 1759 QEKVPVYLKSESIPEKNDEP-VKVVVAK-NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLK 2154
            QE++   ++  S P+    P V + + K NFD++VN+    +L+EFYAPWCGHCK LAP+YE+ AK+LS  S  I +AK+DAT   D+   ++VSG+PT+       K  P  Y+  RE   ++ Y+  ++  P K
Sbjct:  153 QEEIVAKVREVSQPDWTPPPEVTLSLTKDNFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLAKRFDVSGYPTLKIF---RKGRPFDYNGPREKYGIVDYMIEQSGPPSK 284

HSP 5 Score: 74.7146 bits (182), Expect = 2.341e-13
Identity = 42/79 (53.16%), Postives = 55/79 (69.62%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDAT-ANDVPSPYEVSGFPTI 2046
            V V+   NFD  V D  KD VL+EFYAPWCGHCK  AP+YE++A  L   +  I +AK+DAT A+ + S ++VSG+PTI
Sbjct:   60 VWVLNDGNFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTI 136

HSP 6 Score: 62.7734 bits (151), Expect = 1.180e-9
Identity = 28/59 (47.46%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK+L P Y       K Q   + IAK+D TA   T +++ V G+PT+
Sbjct:  542 VLIEFYAPWCGHCKQLEPIYTSLGKKYKGQK-DLVIAKMDATANDITNDQYKVEGFPTI 599

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: P4hb (prolyl 4-hydroxylase, beta polypeptide [Source:MGI Symbol;Acc:MGI:97464])

HSP 1 Score: 126.716 bits (317), Expect = 3.258e-30
Identity = 74/210 (35.24%), Postives = 118/210 (56.19%), Query Frame = 1

Query: 1573 GKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFKMIAD-FSMENLEKFINDFLQEKVPVYLKSESIPEKND-EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            GK +   I +    NQ + E+ G++  +   V +   +E   K+K  +D  + E + +F + FL+ K+  +L S+ +PE  D +PVKV+V  NF+E+  D  K+V +EFYAPWCGHCK LAP +++L +      +I+IAKMD+TAN+V +  +V  FPT+ F P ++  +   Y+  R +D   K++ S         D  G D   DL
Sbjct:  286 GKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEA-VKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQ------DGAGDDEDLDL 488

HSP 2 Score: 126.331 bits (316), Expect = 3.842e-30
Identity = 73/199 (36.68%), Postives = 114/199 (57.29%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAF--DYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNY-KNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            H  +LVEFYAPWCGHCK LAPEY  AA  LK +   I +AKVD T E+   +++GV GYPT+K FKNG  A   +Y+  R AD I+ ++  ++GP++  L           S++  V+GFF    SD  K FL  AE ++ D  F  T +  + +K    K+ +V+F       KF++ +  ++G+ ++ ++  +++ N
Sbjct:   43 HKYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVIGFFKDVESDSAKQFLLAAEAID-DIPFGITSNSGVFSKYQLDKDGVVLF------KKFDEGRNNFEGEITKEKLLDFIKHN 234

HSP 3 Score: 91.2781 bits (225), Expect = 9.348e-19
Identity = 51/105 (48.57%), Postives = 71/105 (67.62%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            V V+   NF+E +    K +L+EFYAPWCGHCK+LAP+Y + A KL AE S+I +AK+DAT  +D+   Y V G+PTI F       SPK Y++GRE DD++ ++
Sbjct:   28 VLVLKKSNFEEALA-AHKYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWL 131

HSP 4 Score: 70.8626 bits (172), Expect = 3.117e-12
Identity = 39/88 (44.32%), Postives = 51/88 (57.95%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYMVS 272
            + VEFYAPWCGHCK+LAP ++      K  +  I IAK+D TA     E   V  +PTLK F     +   DY+GER+ DG  K++ S
Sbjct:  390 VFVEFYAPWCGHCKQLAPIWDKLGETYKDHE-NIIIAKMDSTA--NEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLES 474

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia3 (protein disulfide isomerase associated 3 [Source:MGI Symbol;Acc:MGI:95834])

HSP 1 Score: 114.005 bits (284), Expect = 2.303e-29
Identity = 52/81 (64.20%), Postives = 63/81 (77.78%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADG 251
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ A  Y G R+A G
Sbjct:   23 GLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTAGG 100

HSP 2 Score: 68.9366 bits (167), Expect = 1.390e-13
Identity = 34/73 (46.58%), Postives = 50/73 (68.49%), Query Frame = 1

Query: 1837 KNFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTI 2046
            +NF+  V+D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+
Sbjct:   10 ENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTL 80

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Match: Pdia2 (protein disulfide isomerase associated 2 [Source:MGI Symbol;Acc:MGI:1916441])

HSP 1 Score: 113.62 bits (283), Expect = 4.960e-28
Identity = 57/122 (46.72%), Postives = 79/122 (64.75%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAF--DYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFF 362
            EHS ++VEFYAPWCGHCK+LAPEY  AA  L  +   + +AKVD  AE +  ++  V GYPTLK F+NG      +Y+G ++A+GI +++  + GPS+  L+ EE      A  D VV+GFF
Sbjct:   53 EHSALMVEFYAPWCGHCKELAPEYSKAAALLAAESAVVTLAKVDGPAEPELTKEFEVVGYPTLKFFQNGNRTNPEEYAGPKTAEGIAEWLRRRVGPSATHLEDEEGVQALMAKWDMVVIGFF 174

HSP 2 Score: 69.707 bits (169), Expect = 7.690e-13
Identity = 33/86 (38.37%), Postives = 58/86 (67.44%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIV-IAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            +++EFYAPWCGHCK LAP+Y + A  L+AES +V +AK+D  A  ++   +EV G+PT+ F    ++ +P+ Y+  +  + + +++
Sbjct:   57 LMVEFYAPWCGHCKELAPEYSKAAALLAAESAVVTLAKVDGPAEPELTKEFEVVGYPTLKFFQNGNRTNPEEYAGPKTAEGIAEWL 142

[Close]

BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|P38657|PDIA3_BOVIN (Protein disulfide-isomerase A3 OS=Bos taurus OX=9913 GN=PDIA3 PE=2 SV=1)

HSP 1 Score: 291.967 bits (746), Expect = 7.268e-89
Identity = 135/247 (54.66%), Postives = 178/247 (72.06%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             G+  H T  N      + L++A Y+VDYEKN KG+NYWRNR++ VAKKF+D+G+ +HFA+++ +  + ELS++G+ES       +  R  + +KF M  +FS +   LE+F+ D+    +  YLKSE IPE ND PVKVVVA+NFDEIVN+  KDVLIEFYAPWCGHCK+L PKY+EL +KL  + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y  GRE+ D + Y+  EA++P
Sbjct:  241 FGICPHMTEDNKDLLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGQKLHFAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYLKREATNP 487

HSP 2 Score: 188.734 bits (478), Expect = 1.213e-50
Identity = 95/198 (47.98%), Postives = 131/198 (66.16%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKY-KGDASEHQIRTWVEENM 596
             ++LVEF+APWCGHCKKLAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+ ++  ++GP+S  LK+EE F KF +  D  VVGFF    S+ +  FL  A  L +++RFAHT  E+L  K +     I +F    + NKFED  V Y +   +  +I+ +++EN+
Sbjct:   46 GLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVPLKSEEEFEKFISDKDASVVGFFKDLFSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYDDDGEGITLFRPSHLTNKFEDKTVAYTEQKMTSGKIKRFIQENI 240

HSP 3 Score: 72.0182 bits (175), Expect = 8.789e-12
Identity = 42/112 (37.50%), Postives = 64/112 (57.14%), Query Frame = 1

Query: 1840 NFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLKN 2157
            NF+  + D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++   A  AS PLK+
Sbjct:   34 NFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESG--AYDGPRTADGIVSHLKKQAGPASVPLKS 141

HSP 4 Score: 67.0106 bits (162), Expect = 3.048e-10
Identity = 37/90 (41.11%), Postives = 48/90 (53.33%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL--KVFKNGQFAFDYSGERSADGIIKYM 266
            E+  +L+EFYAPWCGHCK L P+Y+     L+K DP I IAK+D TA       + V G+PT+        Q    Y G R     I Y+
Sbjct:  393 ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRK-DPNIVIAKMDATA-NDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYL 480

[Close]

BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|Q5RDG4|PDIA3_PONAB (Protein disulfide-isomerase A3 OS=Pongo abelii OX=9601 GN=PDIA3 PE=2 SV=1)

HSP 1 Score: 287.73 bits (735), Expect = 2.830e-87
Identity = 135/247 (54.66%), Postives = 178/247 (72.06%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             G+  H T  N      + L++A Y+VDYEKN KG+NYWRNR++ VAKKF+D+G  ++FA+++ +  + ELS++G+ES       +  R  + +KF M  +FS +   LE+F+ D+    +  YLKSE IPE ND PVKVVVA+NFDEIVN+  KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y  GRE+ D + Y+  EA++P
Sbjct:  241 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNP 487

HSP 2 Score: 191.045 bits (484), Expect = 1.893e-51
Identity = 95/200 (47.50%), Postives = 134/200 (67.00%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN---IVIFHSKKMANKFEDTQVKY-KGDASEHQIRTWVEENM 596
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ A  Y G R+ADGI+ ++  ++GP+S  L+TEE F KF +  D  +VGFF    S+ +  FL  A  L +++RFAHT  E+L  +  Y +N   I++F    + NKFED  V Y +   +  +I+ +++EN+
Sbjct:   46 GLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNE--YDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI 240

HSP 3 Score: 70.4774 bits (171), Expect = 2.547e-11
Identity = 41/111 (36.94%), Postives = 64/111 (57.66%), Query Frame = 1

Query: 1840 NFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLK 2154
            NF+  ++D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++   A  AS PL+
Sbjct:   34 NFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQAGPASVPLR 140

HSP 4 Score: 65.0846 bits (157), Expect = 1.372e-9
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            E+  +L+EFYAPWCGHCK L P+Y+     L K DP I IAK+D TA       + V G+PT+
Sbjct:  393 ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKMDATA-NDVPSPYEVRGFPTI 453

[Close]

BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|P30101|PDIA3_HUMAN (Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4)

HSP 1 Score: 287.73 bits (735), Expect = 2.830e-87
Identity = 135/247 (54.66%), Postives = 178/247 (72.06%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             G+  H T  N      + L++A Y+VDYEKN KG+NYWRNR++ VAKKF+D+G  ++FA+++ +  + ELS++G+ES       +  R  + +KF M  +FS +   LE+F+ D+    +  YLKSE IPE ND PVKVVVA+NFDEIVN+  KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y  GRE+ D + Y+  EA++P
Sbjct:  241 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNP 487

HSP 2 Score: 191.045 bits (484), Expect = 1.893e-51
Identity = 95/200 (47.50%), Postives = 134/200 (67.00%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN---IVIFHSKKMANKFEDTQVKY-KGDASEHQIRTWVEENM 596
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ A  Y G R+ADGI+ ++  ++GP+S  L+TEE F KF +  D  +VGFF    S+ +  FL  A  L +++RFAHT  E+L  +  Y +N   I++F    + NKFED  V Y +   +  +I+ +++EN+
Sbjct:   46 GLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNE--YDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI 240

HSP 3 Score: 70.4774 bits (171), Expect = 2.547e-11
Identity = 41/111 (36.94%), Postives = 64/111 (57.66%), Query Frame = 1

Query: 1840 NFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLK 2154
            NF+  ++D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++   A  AS PL+
Sbjct:   34 NFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQAGPASVPLR 140

HSP 4 Score: 65.0846 bits (157), Expect = 1.372e-9
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            E+  +L+EFYAPWCGHCK L P+Y+     L K DP I IAK+D TA       + V G+PT+
Sbjct:  393 ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKMDATA-NDVPSPYEVRGFPTI 453

[Close]

BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|Q4VIT4|PDIA3_CHLAE (Protein disulfide-isomerase A3 OS=Chlorocebus aethiops OX=9534 GN=PDIA3 PE=2 SV=1)

HSP 1 Score: 287.345 bits (734), Expect = 4.042e-87
Identity = 135/247 (54.66%), Postives = 178/247 (72.06%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
             G+  H T  N      + L++A Y+VDYEKN KG+NYWRNR++ VAKKF+D+G  ++FA+++ +  + ELS++G+ES       +  R  + +KF M  +FS +   LE+F+ D+    +  YLKSE IPE ND PVKVVVA+NFDEIVN+  KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y  GRE+ D + Y+  EA++P
Sbjct:  241 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNP 487

HSP 2 Score: 188.734 bits (478), Expect = 1.025e-50
Identity = 95/200 (47.50%), Postives = 134/200 (67.00%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN---IVIFHSKKMANKFEDTQVKY-KGDASEHQIRTWVEENM 596
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   +AKVDCTA T TC K+GVSGYPTLK+F++G+ A  Y G R+ADGI+ ++  ++GP+S  L+TEE F KF +  D  VVGFF    S+ +  FL  A  L +++RFAHT  ++L  +  Y +N   I++F    + NKFED  V Y +   +  +I+ +++EN+
Sbjct:   46 GLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASVVGFFDDLFSEAHSEFLKAASNLRDNYRFAHTNVKSLVNE--YDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI 240

HSP 3 Score: 71.2478 bits (173), Expect = 1.829e-11
Identity = 42/111 (37.84%), Postives = 64/111 (57.66%), Query Frame = 1

Query: 1840 NFDEIVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLK 2154
            NF+  V+D      +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++   A  AS PL+
Sbjct:   34 NFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQAGPASVPLR 140

HSP 4 Score: 65.0846 bits (157), Expect = 1.325e-9
Identity = 31/63 (49.21%), Postives = 40/63 (63.49%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            E+  +L+EFYAPWCGHCK L P+Y+     L K DP I IAK+D TA       + V G+PT+
Sbjct:  393 ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKMDATA-NDVPSPYEVRGFPTI 453

[Close]

BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Match: sp|Q8JG64|PDIA3_CHICK (Protein disulfide-isomerase A3 OS=Gallus gallus OX=9031 GN=PDIA3 PE=2 SV=1)

HSP 1 Score: 283.878 bits (725), Expect = 8.706e-86
Identity = 135/246 (54.88%), Postives = 172/246 (69.92%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASS 2145
             G+  H T  N      + L+VA Y+VDYEKN KG+NYWRNR++ +AKKF+D+G  + FA+++ +    ELSE+G+++       +  R  +  KF M  +FS +   LE+F+ D+    +  YLKSE +PE ND PVKVVVA+NFDEIVN   KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IVIAKMDATANDVPSPYEV GFPTIYFAP   K SPK Y  GREV D + Y+  EA+S
Sbjct:  239 FGICPHMTEDNKDLIQGKDLLVAYYDVDYEKNAKGSNYWRNRVMMIAKKFLDAGHKLSFAVASRKTFGHELSEFGLDNSVGEAPVVAIRTAKGDKFVMQEEFSRDGKALERFLQDYFDGNLKKYLKSEPVPENNDGPVKVVVAENFDEIVNAEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFAPAGKKQSPKKYEGGREVSDFISYLKREATS 484

HSP 2 Score: 192.971 bits (489), Expect = 3.517e-52
Identity = 92/198 (46.46%), Postives = 131/198 (66.16%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGD-ASEHQIRTWVEENM 596
             ++LVEF+APWCGHCK+LAPEYE AAT LK   P   + KVDCTA + TC K+GVSGYPTLK+F++G+ +  Y G R+ADGI+ ++  ++GP+S  L +  +F KF    D  VVGFF   S D Y  F+  A  L +++RFAHT +E L  K       +V++   ++ANKFED+ VKY  D  +  +I+ +++EN+
Sbjct:   44 GLVLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LVKVDCTANSNTCNKYGVSGYPTLKIFRDGEESGTYDGPRTADGIVSHLKKQAGPASVALSSVADFEKFIGDKDASVVGFFRDASGDAYSEFMKAANNLRDNYRFAHTSEEQLVQKYEEDGEGVVLYRPSRLANKFEDSTVKYTEDKITSAKIKKFIQENI 238

HSP 3 Score: 68.1662 bits (165), Expect = 1.629e-10
Identity = 34/90 (37.78%), Postives = 53/90 (58.89%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            VL+EF+APWCGHCK LAP+YE  A +L  +  + + K+D TAN +  + Y VSG+PT+       +    +Y   R  D ++ ++  +A 
Sbjct:   46 VLVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLVKVDCTANSNTCNKYGVSGYPTLKIFRDGEESG--TYDGPRTADGIVSHLKKQAG 131

HSP 4 Score: 67.3958 bits (163), Expect = 2.431e-10
Identity = 38/90 (42.22%), Postives = 47/90 (52.22%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYM 266
            E   +L+EFYAPWCGHCK L P+Y+     L K DP I IAK+D TA       + V G+PT+     G  Q    Y G R     I Y+
Sbjct:  391 EDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSK-DPNIVIAKMDATA-NDVPSPYEVRGFPTIYFAPAGKKQSPKKYEGGREVSDFISYL 478

[Close]

BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: A0A1I8IGN6 (Protein disulfide-isomerase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005470g3 PE=3 SV=1)

HSP 1 Score: 351.673 bits (901), Expect = 2.373e-109
Identity = 159/259 (61.39%), Postives = 201/259 (77.61%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            G+ GHRT  N KYF K+PL+ A Y VDYE+NPKGTNYWRNRI+KVAKK+  +G  +HF+++N + M+ ELSE+G++SPD  KVY+ A++++ QKFKM  DF+M+  + F+ D    ++  YLKSE  PE    PVK+ VAKNFD++VNDPTKDVLIEFYAPWCGHCKSLAPKY+ELA+KLS E+D+VIAKMDATANDVP PY+V GFPTIYFAPK  K  PK Y  GREV+D + Y+A EA+  L+ +DR G  +K DL
Sbjct:  235 GMVGHRTSGNSKYF-KQPLVTAYYGVDYERNPKGTNYWRNRIMKVAKKY--TGTGLHFSVANSKAMSFELSEFGVDSPDEQKVYVAAKNDKGQKFKMAEDFTMDAFDAFLTDLQAGRLTPYLKSEPEPESQSAPVKIAVAKNFDKLVNDPTKDVLIEFYAPWCGHCKSLAPKYDELAEKLSGETDLVIAKMDATANDVPPPYDVRGFPTIYFAPKGGKSQPKQYQGGREVNDFITYLAKEATDELRGYDRAGNRKKQDL 490

HSP 2 Score: 229.18 bits (583), Expect = 5.643e-63
Identity = 101/195 (51.79%), Postives = 134/195 (68.72%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            + LVEFYAPWCGHCK+LAP+YE AAT LK  DPP+ + KVDCTAET  C K+GVSGYPTLK+FKNG+ + DY+G R ADGI+KYM SK+GPSS+ LK     +K  A  +P VV FF+SES+    AF   A+ L+EDF FAH+    +++K  + + +VI     + +KFED ++ Y G      +R W+E N+
Sbjct:   39 IALVEFYAPWCGHCKRLAPQYEEAATRLKSSDPPVPLVKVDCTAETAVCGKYGVSGYPTLKIFKNGEVSSDYNGPREADGIVKYMKSKAGPSSRLLKDASGLDKLMAGQEPFVVAFFSSESASGLSAFKQAADSLSEDFAFAHSVSADINSKFGFNDQVVIMRPTVLQSKFEDNKLAYSGAMDSGALRAWIEANI 233

HSP 3 Score: 81.2629 bits (199), Expect = 3.456e-12
Identity = 47/103 (45.63%), Postives = 65/103 (63.11%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NFD  + D  +  L+EFYAPWCGHCK LAP+YEE A +L S++  + + K+D TA   V   Y VSG+PT+    KN + S   Y+  RE D ++KY+ S+A 
Sbjct:   29 NFDSRIKD-LEIALVEFYAPWCGHCKRLAPQYEEAATRLKSSDPPVPLVKVDCTAETAVCGKYGVSGYPTLKIF-KNGEVS-SDYNGPREADGIVKYMKSKAG 128

HSP 4 Score: 62.3882 bits (150), Expect = 2.597e-6
Identity = 34/90 (37.78%), Postives = 49/90 (54.44%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAF--DYSGERSADGIIKYMVSKS 278
            +L+EFYAPWCGHCK LAP+Y+  A  L  +   + IAK+D TA       + V G+PT+     G  +    Y G R  +  I Y+  ++
Sbjct:  385 VLIEFYAPWCGHCKSLAPKYDELAEKLSGET-DLVIAKMDATA-NDVPPPYDVRGFPTIYFAPKGGKSQPKQYQGGREVNDFITYLAKEA 472

[Close]

BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: A0A1I8IJ81 (Protein disulfide-isomerase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005470g1 PE=3 SV=1)

HSP 1 Score: 351.288 bits (900), Expect = 2.844e-109
Identity = 159/259 (61.39%), Postives = 201/259 (77.61%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            G+ GHRT  N KYF K+PL+ A Y VDYE+NPKGTNYWRNRI+KVAKK+  +G  +HF+++N + M+ ELSE+G++SPD  KVY+ A++++ QKFKM  DF+M+  + F+ D    ++  YLKSE  PE    PVK+ VAKNFD++VNDPTKDVLIEFYAPWCGHCKSLAPKY+ELA+KLS E+D+VIAKMDATANDVP PY+V GFPTIYFAPK  K  PK Y  GREV+D + Y+A EA+  L+ +DR G  +K DL
Sbjct:  235 GMVGHRTSGNSKYF-KQPLVTAYYGVDYERNPKGTNYWRNRIMKVAKKY--TGTGLHFSVANSKAMSFELSEFGVDSPDEQKVYVAAKNDKGQKFKMAEDFTMDAFDAFLTDMQAGRLTPYLKSEPEPESQSAPVKIAVAKNFDKLVNDPTKDVLIEFYAPWCGHCKSLAPKYDELAEKLSGETDLVIAKMDATANDVPPPYDVRGFPTIYFAPKGGKSQPKQYQGGREVNDFITYLAKEATDELRGYDRAGNRKKQDL 490

HSP 2 Score: 229.18 bits (583), Expect = 5.473e-63
Identity = 101/195 (51.79%), Postives = 134/195 (68.72%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            + LVEFYAPWCGHCK+LAP+YE AAT LK  DPP+ + KVDCTAET  C K+GVSGYPTLK+FKNG+ + DY+G R ADGI+KYM SK+GPSS+ LK     +K  A  +P VV FF+SES+    AF   A+ L+EDF FAH+    +++K  + + +VI     + +KFED ++ Y G      +R W+E N+
Sbjct:   39 IALVEFYAPWCGHCKRLAPQYEEAATRLKSSDPPVPLVKVDCTAETAVCGKYGVSGYPTLKIFKNGEVSSDYNGPREADGIVKYMKSKAGPSSRLLKDASGLDKLMAGQEPFVVAFFSSESASGLSAFKQAADSLSEDFAFAHSVSADINSKFGFNDQVVIMRPTVLQSKFEDNKLAYSGAMDSGALRAWIEANI 233

HSP 3 Score: 81.2629 bits (199), Expect = 3.395e-12
Identity = 47/103 (45.63%), Postives = 65/103 (63.11%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            NFD  + D  +  L+EFYAPWCGHCK LAP+YEE A +L S++  + + K+D TA   V   Y VSG+PT+    KN + S   Y+  RE D ++KY+ S+A 
Sbjct:   29 NFDSRIKD-LEIALVEFYAPWCGHCKRLAPQYEEAATRLKSSDPPVPLVKVDCTAETAVCGKYGVSGYPTLKIF-KNGEVS-SDYNGPREADGIVKYMKSKAG 128

HSP 4 Score: 62.3882 bits (150), Expect = 2.689e-6
Identity = 34/90 (37.78%), Postives = 49/90 (54.44%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAF--DYSGERSADGIIKYMVSKS 278
            +L+EFYAPWCGHCK LAP+Y+  A  L  +   + IAK+D TA       + V G+PT+     G  +    Y G R  +  I Y+  ++
Sbjct:  385 VLIEFYAPWCGHCKSLAPKYDELAEKLSGET-DLVIAKMDATA-NDVPPPYDVRGFPTIYFAPKGGKSQPKQYQGGREVNDFITYLAKEA 472

[Close]

BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: T1G058 (Protein disulfide-isomerase OS=Helobdella robusta OX=6412 GN=20214456 PE=3 SV=1)

HSP 1 Score: 346.665 bits (888), Expect = 1.813e-107
Identity = 167/258 (64.73%), Postives = 202/258 (78.29%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIE-SPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKS 2187
            G+ GHRT  NV  F +RPLI   Y+VDY KNPKGTNYWRNRI+KVAKK  + GK++HFAISN  + N EL+E+G+  S D  K+ + AR+ ++QKF M  DFS++ LEKF NDFL+  +  YLKSE++P  ND PVKVVVA+ FD+IVND TKDVLIEFYAPWCGHCKSLAPKYEELA+KL+ E DIVIAKMDATANDVP+PY+V GFPTIYFAPKNSK  PK Y  GREVDD +KY+A E++ PL  + R G+  K+
Sbjct:  231 GMVGHRTTGNVAQF-ERPLITVYYDVDYVKNPKGTNYWRNRIIKVAKKLSEEGKNVHFAISNADQFNHELTEHGLTYSAD--KLVVAARNAKDQKFSMTEDFSVDALEKFANDFLEGNLKPYLKSEAVPTSNDGPVKVVVAEEFDKIVNDETKDVLIEFYAPWCGHCKSLAPKYEELAQKLAEEEDIVIAKMDATANDVPAPYDVKGFPTIYFAPKNSKKFPKRYEGGREVDDFIKYLAKESTDPLTKYTRDGKKIKA 485

HSP 2 Score: 213.772 bits (543), Expect = 2.372e-57
Identity = 98/182 (53.85%), Postives = 134/182 (73.63%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETK-TCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYK 548
            + + LV+F+APWCGHCKKLAPE+E AAT LK+ DPP+ + +VDCT   K +C KHGVSGYPTLKVFK G+FAFDY G R ADGI+KYM  K+GPSSKELK+ ++  KF  + DP V+GFF S SS+    F  +A  L+++FRFAHTFD ++ +  NY+  IV++   ++ +K E +++ Y+
Sbjct:   37 YEIALVKFFAPWCGHCKKLAPEFERAATILKRNDPPVILVEVDCTEGGKDSCSKHGVSGYPTLKVFKQGEFAFDYEGPRDADGIVKYMKGKAGPSSKELKSLDDVKKFLDNFDPSVIGFFKSSSSEENVQFQKLASALSDNFRFAHTFDPSVLSHYNYEGKIVMYQPPRLHSKMEPSELVYE 218

HSP 3 Score: 72.4034 bits (176), Expect = 1.855e-9
Identity = 41/90 (45.56%), Postives = 54/90 (60.00%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNG-QFAFDYSGERSADGIIKYMVSKS 278
            +L+EFYAPWCGHCK LAP+YE  A  L +++  I IAK+D TA       + V G+PT+    KN  +F   Y G R  D  IKY+  +S
Sbjct:  382 VLIEFYAPWCGHCKSLAPKYEELAQKLAEEE-DIVIAKMDATA-NDVPAPYDVKGFPTIYFAPKNSKKFPKRYEGGREVDDFIKYLAKES 469

HSP 4 Score: 61.2326 bits (147), Expect = 7.176e-6
Identity = 35/101 (34.65%), Postives = 56/101 (55.45%), Query Frame = 1

Query: 1879 LIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDAT--ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI---ASEASSPLKNFD 2163
            L++F+APWCGHCK LAP++E  A  L   +  +++ ++D T    D  S + VSG+PT+    +        Y   R+ D ++KY+   A  +S  LK+ D
Sbjct:   41 LVKFFAPWCGHCKKLAPEFERAATILKRNDPPVILVEVDCTEGGKDSCSKHGVSGYPTLKVFKQG--EFAFDYEGPRDADGIVKYMKGKAGPSSKELKSLD 139

[Close]

BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: K1Q7T5 (Protein disulfide-isomerase OS=Crassostrea gigas OX=29159 GN=CGI_10011652 PE=3 SV=1)

HSP 1 Score: 345.51 bits (885), Expect = 5.587e-107
Identity = 165/253 (65.22%), Postives = 195/253 (77.08%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQG 2172
            +GL GHRT SN + F K+PL+VA Y+VDY KN KGTNYWRNR++KVAKK  D GK I FA+SN ++ + EL E+G+      K  +  RDER++K+ M  +FSM+NLEKF+ DFL +KV  YLKSE +P+  D PVKVVVAKNFDEIVND  +DVLIEFYAPWCGHCK L PKY EL +KL+ ES I IAKMDATANDV  PYEVSGFPTIYFAPK SK+SPK YS GREVDD LKY+A EA++ L  FDR G
Sbjct:  231 LGLCGHRTQSNAEKF-KKPLVVAFYDVDYVKNEKGTNYWRNRVMKVAKKIQDEGKKIFFAVSNSKDFSYELGEFGLGDVSGEKPVVAVRDERDRKYVMSDEFSMDNLEKFVRDFLDDKVEPYLKSEPVPDNTDAPVKVVVAKNFDEIVNDSERDVLIEFYAPWCGHCKQLEPKYTELGEKLAEESGITIAKMDATANDVAKPYEVSGFPTIYFAPKGSKNSPKRYSGGREVDDFLKYLAKEATNELSGFDRDG 482

HSP 2 Score: 233.417 bits (594), Expect = 1.266e-64
Identity = 104/198 (52.53%), Postives = 146/198 (73.74%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            +H +ILVEF+APWCGHCKKLAPEYE AAT+LK  DPP+ +AKVDCTA  +TC+K GVSGYPTLK+F+ G+F+ +Y G R ADGIIKYM +++GP+SKEL    +  KF + AD  V+GFF    S+L K F  VA+ ++ D +FAHT  + +  K  +KN+IV++  K++ NKFE +++KY  DA+ ++I+ W+  N+
Sbjct:   33 DHELILVEFFAPWCGHCKKLAPEYERAATSLKDNDPPVPLAKVDCTASEETCKKFGVSGYPTLKIFRAGEFSEEYGGPREADGIIKYMQTRAGPTSKELNNVADAEKFLSKADYGVIGFFEDGESELAKTFQKVADAMSTDLKFAHTSSKAVLDKYGFKNDIVLYQPKRLRNKFEPSELKYTDDATVYKIKEWLNNNI 230

HSP 3 Score: 70.0922 bits (170), Expect = 9.562e-9
Identity = 38/93 (40.86%), Postives = 57/93 (61.29%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDATAN-DVPSPYEVSGFPT--IYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EF+APWCGHCK LAP+YE  A  L   +  + +AK+D TA+ +    + VSG+PT  I+ A + S+     Y   RE D ++KY+ + A 
Sbjct:   37 ILVEFFAPWCGHCKKLAPEYERAATSLKDNDPPVPLAKVDCTASEETCKKFGVSGYPTLKIFRAGEFSEE----YGGPREADGIIKYMQTRAG 125

HSP 4 Score: 67.781 bits (164), Expect = 6.460e-8
Identity = 36/90 (40.00%), Postives = 51/90 (56.67%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYMVSKS 278
            +L+EFYAPWCGHCK+L P+Y      L  ++  I IAK+D TA     + + VSG+PT+     G       YSG R  D  +KY+  ++
Sbjct:  384 VLIEFYAPWCGHCKQLEPKYTELGEKL-AEESGITIAKMDATA-NDVAKPYEVSGFPTIYFAPKGSKNSPKRYSGGREVDDFLKYLAKEA 471

[Close]

BLAST of Protein disulfide-isomerase vs. TrEMBL
Match: R7UDG3 (Protein disulfide-isomerase OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_164804 PE=3 SV=1)

HSP 1 Score: 344.354 bits (882), Expect = 1.313e-106
Identity = 167/259 (64.48%), Postives = 201/259 (77.61%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            GLAG RT SN++ F K+PL+VA Y+VDY KN KGTNYWRNR++KVAKKF   GK++ FAI++  + + EL+E+G++  D  K  + ARD  NQKF M  +FSM+NLE F+ DFL  K+  YLKSE IP   D+ VKVVVAKNFDEIVND +KDVLIEFYAPWCGHCKSLAPKYEELA KL+ E DIVIAKMDATANDVP  YEV GFPT++F+PK SK SP  Y  GREV+D LKYIA  A+ PLK +DR G+ +KS+L
Sbjct:  235 GLAGQRTTSNLEQF-KQPLVVAYYDVDYVKNAKGTNYWRNRVMKVAKKF--EGKTVFFAIASTDDFSPELNEFGMQVSDDGKPIVAARDASNQKFIMTQEFSMDNLEAFVTDFLDGKLEPYLKSEPIPATQDDAVKVVVAKNFDEIVNDESKDVLIEFYAPWCGHCKSLAPKYEELATKLAKEEDIVIAKMDATANDVPKQYEVRGFPTLFFSPKGSKMSPLKYEGGREVEDFLKYIAKTATDPLKGYDRNGKKKKSEL 490

HSP 2 Score: 249.98 bits (637), Expect = 8.612e-71
Identity = 110/198 (55.56%), Postives = 150/198 (75.76%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            ++ V LV+FYAPWCGHCKKLAPE+E A++ L   DPP+A+ KVDCT ETK C+KHGVSGYPTLK+F+ G+ A DY+G R ADGI+K M SK+GPSSK+L TE     +    + V++GFF SE S+L K F  +A+ L+EDFRFAH+ D+ ++ K +Y  ++VI   KKMANKFE++ VKY G+AS H+++TW+ +N+
Sbjct:   36 DYGVALVKFYAPWCGHCKKLAPEFERASSVLASDDPPVALVKVDCTTETKICQKHGVSGYPTLKIFRGGELAEDYNGPRDADGIVKVMRSKAGPSSKQLMTEAQVEAYMNKEENVILGFFDSEHSELLKQFKKLADALSEDFRFAHSVDKDVNAKFSYSEDVVIVRPKKMANKFEESTVKYSGEASLHKMKTWLHDNV 233

HSP 3 Score: 73.559 bits (179), Expect = 8.437e-10
Identity = 39/86 (45.35%), Postives = 52/86 (60.47%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYM 266
            +L+EFYAPWCGHCK LAP+YE  AT L K++  I IAK+D TA     +++ V G+PTL     G       Y G R  +  +KY+
Sbjct:  385 VLIEFYAPWCGHCKSLAPKYEELATKLAKEE-DIVIAKMDATA-NDVPKQYEVRGFPTLFFSPKGSKMSPLKYEGGREVEDFLKYI 468

HSP 4 Score: 62.003 bits (149), Expect = 3.341e-6
Identity = 35/110 (31.82%), Postives = 60/110 (54.55%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            V V+   NF+  + D     L++FYAPWCGHCK LAP++E  +  L+++   + + K+D T    +   + VSG+PT+           + Y+  R+ D ++K + S+A 
Sbjct:   22 VVVLTDANFESAIAD-YGVALVKFYAPWCGHCKKLAPEFERASSVLASDDPPVALVKVDCTTETKICQKHGVSGYPTLKIF--RGGELAEDYNGPRDADGIVKVMRSKAG 128

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:103022595])

HSP 1 Score: 286.574 bits (732), Expect = 6.804e-88
Identity = 134/248 (54.03%), Postives = 176/248 (70.97%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             G+  H T  N  +   + L+VA Y+VDY+KNPKG+NYWRNR++KVAK F+D GK + FA++N    + ++SE G+++       +  R  +  K+ M  +FS +   LE+F+ D+   K+  YLKSE IPE ND PVKVVVA+NFD IVND +KDVLIEFYAPWCGHCKSL PKY+EL +KL+ + ++VIAKMDATANDVPS Y+V GFPTIYF+P   K +PK Y  GREV D + Y+  EAS+PL
Sbjct:  230 FGMCPHMTEDNKDHLKGKDLLVAYYDVDYDKNPKGSNYWRNRVMKVAKGFLDEGKKLSFAVANKNSFSHDVSELGLDASGGELPVVGIRTAKGDKYVMQEEFSRDGKALERFLQDYFDGKLKRYLKSEPIPENNDGPVKVVVAENFDSIVNDDSKDVLIEFYAPWCGHCKSLEPKYKELGEKLANDPNVVIAKMDATANDVPSSYDVRGFPTIYFSPAGQKQNPKRYEGGREVSDFISYLKKEASNPL 477

HSP 2 Score: 189.504 bits (480), Expect = 5.247e-52
Identity = 93/200 (46.50%), Postives = 132/200 (66.00%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDA-SEHQIRTWVEENM 596
            +H +ILVEF+APWCGHCK+LAPEYE AAT LK     +++AKVDCTA +  C K+GVSGYPTLK+F++G+ +  Y G R+ADGI+ ++  ++GP+S ELKT  +F KF    D  VVGFF    S     FL  A  L E +RFAHT  E L  K +     +V+F   ++ NKFE++ VK+  D  +  +I+ ++++N+
Sbjct:   33 DHDLILVEFFAPWCGHCKRLAPEYEAAATRLKGI---VSLAKVDCTANSNVCSKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVELKTVADFEKFIGDRDASVVGFFADGGSAAQSEFLKSASALRESYRFAHTNLEDLLKKSDIDGEGVVLFRPPRLNNKFEESSVKFSEDKFTNAKIKRFIQDNI 229

HSP 3 Score: 72.7886 bits (177), Expect = 5.881e-13
Identity = 36/90 (40.00%), Postives = 55/90 (61.11%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EF+APWCGHCK LAP+YE  A +L  +  + +AK+D TAN +V S Y VSG+PT+       +    +Y   R  D ++ ++  +A 
Sbjct:   37 ILVEFFAPWCGHCKRLAPEYEAAATRL--KGIVSLAKVDCTANSNVCSKYGVSGYPTLKIFRDGEESG--AYDGPRTADGIVSHLKKQAG 122

HSP 4 Score: 65.0846 bits (157), Expect = 1.337e-10
Identity = 35/86 (40.70%), Postives = 45/86 (52.33%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYM 266
            +L+EFYAPWCGHCK L P+Y+     L   DP + IAK+D TA       + V G+PT+     G  Q    Y G R     I Y+
Sbjct:  386 VLIEFYAPWCGHCKSLEPKYKELGEKL-ANDPNVVIAKMDATA-NDVPSSYDVRGFPTIYFSPAGQKQNPKRYEGGREVSDFISYL 469

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: pdia7 (protein disulfide-isomerase A3-like [Source:NCBI gene;Acc:103024123])

HSP 1 Score: 260.766 bits (665), Expect = 3.370e-78
Identity = 129/249 (51.81%), Postives = 166/249 (66.67%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             GL  H T  N +    R L+ A Y+VDY +NPKGTNYWRNR++KVA +F   G S  FA+++  +   EL E +G+         IT R    QK+ M  +F+ +   LEKF+ D+  +++  Y+KSE+ PE N  PVKVVVA  F+EIVN+P KDVL+EFYAPWCGHCK+L PKY EL KKLS++ +IVIAKMDATANDVP  Y+V GFPTIYFAP   K  P+ Y  GREV D + ++  EA+ PL
Sbjct:  232 FGLCPHLTSENKEVLWARDLLTAYYDVDYVRNPKGTNYWRNRVMKVATQFQSRGLS--FAVADQVDFLDELEEEFGLGLSGGELPVITIRTRAGQKYTMQEEFTRDGKSLEKFLEDYFAKRLKPYVKSEAAPESNGGPVKVVVANTFEEIVNNPEKDVLVEFYAPWCGHCKNLEPKYTELGKKLSSDPNIVIAKMDATANDVPLDYDVQGFPTIYFAPAGQKEQPRRYEGGREVSDFISFLKKEATHPL 478

HSP 2 Score: 181.8 bits (460), Expect = 2.906e-49
Identity = 87/199 (43.72%), Postives = 127/199 (63.82%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EH  +LVEF+APWCGHC++LAPEYE AAT LK     +++AKVDCT  +KTCE   V+GYPTLK+F+NG+ A  Y G R+ADGI+ YM  ++GPSS  L +E + + F  + D  VVGFF+   S     FL  +  L + +RFAH  D  +  K    + ++++F    + +KFE++ VK+    S   +RT++ +N+
Sbjct:   36 EHDTLLVEFFAPWCGHCQRLAPEYEAAATRLKGT---VSLAKVDCTVNSKTCETFVVNGYPTLKIFQNGEEASSYDGPRTADGIVSYMKKQAGPSSVPLHSEADLDSFINTFDASVVGFFSGPDSLQLAEFLKASSALRDSYRFAHATDLKIGLKHGVNSESVLLFRPPHLNSKFEESVVKFTESVSTAALRTFIRDNI 231

HSP 3 Score: 67.3958 bits (163), Expect = 2.613e-11
Identity = 33/90 (36.67%), Postives = 52/90 (57.78%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAND-VPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EF+APWCGHC+ LAP+YE  A +L  +  + +AK+D T N      + V+G+PT+       + S  SY   R  D ++ Y+  +A 
Sbjct:   40 LLVEFFAPWCGHCQRLAPEYEAAATRL--KGTVSLAKVDCTVNSKTCETFVVNGYPTLKIFQNGEEAS--SYDGPRTADGIVSYMKKQAG 125

HSP 4 Score: 65.0846 bits (157), Expect = 1.310e-10
Identity = 36/86 (41.86%), Postives = 45/86 (52.33%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQ--FAFDYSGERSADGIIKYM 266
            +LVEFYAPWCGHCK L P+Y      L   DP I IAK+D TA     + + V G+PT+     GQ      Y G R     I ++
Sbjct:  387 VLVEFYAPWCGHCKNLEPKYTELGKKL-SSDPNIVIAKMDATANDVPLD-YDVQGFPTIYFAPAGQKEQPRRYEGGREVSDFISFL 470

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: pdia8 (protein disulfide-isomerase A3-like [Source:NCBI gene;Acc:103028648])

HSP 1 Score: 258.84 bits (660), Expect = 1.885e-77
Identity = 126/250 (50.40%), Postives = 169/250 (67.60%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             G+  H T  N+    KR L+ A Y++DY  NPKG+NYWRNR++KVA ++  S + + F+++N ++   EL E YG+ S + S+V ++T R     K+ M  +F+ +   LE+F+ D+    +  Y+KSE +P KN+ PVKVVVA  F+EIVNDP KDVLIEFYAPWCGHCK L PKY EL ++LS++ +IVIAKMDATANDVP  Y+V GFPTIYF P   K  PK Y   REV D L ++  EA+S L
Sbjct:  238 FGICPHLTKENIDQLRKRDLLTAYYDLDYVHNPKGSNYWRNRVMKVASQY--SSRGLLFSVANRKDFEDELEEDYGLGSTEGSEVPFVTIRTRLGHKYSMREEFTRDGKSLERFLEDYYANSLKRYIKSEPVPAKNNGPVKVVVADTFEEIVNDPEKDVLIEFYAPWCGHCKKLEPKYTELGQELSSDPNIVIAKMDATANDVPEGYDVHGFPTIYFVPAGRKAEPKRYEGAREVKDFLNFLKREATSSL 485

HSP 2 Score: 176.792 bits (447), Expect = 1.560e-47
Identity = 89/199 (44.72%), Postives = 122/199 (61.31%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EH  +LV+FYAPWCGHCKKLAPE+E AA  LK     + +AKVDCT+ T+ C + GV+GYPTLK+F+NG+ +  Y G RSA GI+  M  ++GP S  L  E++   F    D  VVG F S  S     FL  A  + E FRFAHT D  L  K N  +  I++F   ++A+KFE++ V + G  S   +R ++ +N+
Sbjct:   42 EHETMLVKFYAPWCGHCKKLAPEFETAAKRLKGV---VTLAKVDCTSSTEVCGRFGVTGYPTLKIFRNGRESSSYDGPRSAVGIVDQMKKQAGPDSVPLHNEKDLETFVNHYDASVVGVFESSDSPQLVEFLKGANLMRESFRFAHTTDLQLGLKYNLTSEGILLFRPPRLASKFEESVVSHTGPFSVTALRRFIRDNI 237

HSP 3 Score: 69.3218 bits (168), Expect = 7.579e-12
Identity = 47/142 (33.10%), Postives = 78/142 (54.93%), Query Frame = 1

Query: 1744 INDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGRE---VDDMLKYIASEASSPLKN 2157
            ++  L   + V L   S+  ++D  V  +   +FD +  +  + +L++FYAPWCGHCK LAP++E  AK+L     + +AK+D T++ +V   + V+G+PT+    +N + S  SY   R    + D +K  A   S PL N
Sbjct:    5 VSGLLSGALFVCLWGGSVSARSD--VVELTDVDFDYVAAE-HETMLVKFYAPWCGHCKKLAPEFETAAKRLKGV--VTLAKVDCTSSTEVCGRFGVTGYPTLKIF-RNGRES-SSYDGPRSAVGIVDQMKKQAGPDSVPLHN 139

HSP 4 Score: 67.3958 bits (163), Expect = 2.827e-11
Identity = 36/86 (41.86%), Postives = 47/86 (54.65%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFA--FDYSGERSADGIIKYM 266
            +L+EFYAPWCGHCKKL P+Y      L   DP I IAK+D TA     E + V G+PT+     G+ A    Y G R     + ++
Sbjct:  394 VLIEFYAPWCGHCKKLEPKYTELGQEL-SSDPNIVIAKMDATA-NDVPEGYDVHGFPTIYFVPAGRKAEPKRYEGAREVKDFLNFL 477

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: pdia8 (protein disulfide-isomerase A3-like [Source:NCBI gene;Acc:103028648])

HSP 1 Score: 226.098 bits (575), Expect = 2.274e-65
Identity = 117/250 (46.80%), Postives = 161/250 (64.40%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             G+  H T  N+    KR L+ A Y++DY  NPKG+NYWRNR++KVA ++  S + + F+++N ++   EL E YG+ S + S+V ++T R     K+ M  +F+ +   LE+F+ D+    +  Y+KSE +P KN+ PVKVVVA  F+EIVNDP KDVLIEFYAPWCGHCK L PKY EL ++LS++ +IVIAKMDATANDVP  Y+V G+          K  P      REV D L ++  EA+S L
Sbjct:  238 FGICPHLTKENIDQLRKRDLLTAYYDLDYVHNPKGSNYWRNRVMKVASQY--SSRGLLFSVANRKDFEDELEEDYGLGSTEGSEVPFVTIRTRLGHKYSMREEFTRDGKSLERFLEDYYANSLKRYIKSEPVPAKNNGPVKVVVADTFEEIVNDPEKDVLIEFYAPWCGHCKKLEPKYTELGQELSSDPNIVIAKMDATANDVPEGYDVHGY---------VKQPP----GAREVKDFLNFLKREATSSL 472

HSP 2 Score: 176.792 bits (447), Expect = 1.203e-47
Identity = 89/199 (44.72%), Postives = 122/199 (61.31%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKN-NIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EH  +LV+FYAPWCGHCKKLAPE+E AA  LK     + +AKVDCT+ T+ C + GV+GYPTLK+F+NG+ +  Y G RSA GI+  M  ++GP S  L  E++   F    D  VVG F S  S     FL  A  + E FRFAHT D  L  K N  +  I++F   ++A+KFE++ V + G  S   +R ++ +N+
Sbjct:   42 EHETMLVKFYAPWCGHCKKLAPEFETAAKRLKGV---VTLAKVDCTSSTEVCGRFGVTGYPTLKIFRNGRESSSYDGPRSAVGIVDQMKKQAGPDSVPLHNEKDLETFVNHYDASVVGVFESSDSPQLVEFLKGANLMRESFRFAHTTDLQLGLKYNLTSEGILLFRPPRLASKFEESVVSHTGPFSVTALRRFIRDNI 237

HSP 3 Score: 69.3218 bits (168), Expect = 7.510e-12
Identity = 47/142 (33.10%), Postives = 78/142 (54.93%), Query Frame = 1

Query: 1744 INDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGRE---VDDMLKYIASEASSPLKN 2157
            ++  L   + V L   S+  ++D  V  +   +FD +  +  + +L++FYAPWCGHCK LAP++E  AK+L     + +AK+D T++ +V   + V+G+PT+    +N + S  SY   R    + D +K  A   S PL N
Sbjct:    5 VSGLLSGALFVCLWGGSVSARSD--VVELTDVDFDYVAAE-HETMLVKFYAPWCGHCKKLAPEFETAAKRLKGV--VTLAKVDCTSSTEVCGRFGVTGYPTLKIF-RNGRES-SSYDGPRSAVGIVDQMKKQAGPDSVPLHN 139

HSP 4 Score: 61.6178 bits (148), Expect = 1.698e-9
Identity = 30/56 (53.57%), Postives = 35/56 (62.50%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGY 182
            +L+EFYAPWCGHCKKL P+Y      L   DP I IAK+D TA     E + V GY
Sbjct:  394 VLIEFYAPWCGHCKKLEPKYTELGQEL-SSDPNIVIAKMDATA-NDVPEGYDVHGY 447

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Match: pdia8 (protein disulfide-isomerase A3-like [Source:NCBI gene;Acc:103028648])

HSP 1 Score: 214.927 bits (546), Expect = 1.646e-61
Identity = 113/250 (45.20%), Postives = 159/250 (63.60%), Query Frame = 1

Query: 1411 SMGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADF-SMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            + G+  H T  N+    KR L+ A Y++DY  NPKG+NYWRN ++KVA ++  S + + F+++N ++   EL E YG+ S + S+V ++T R     K+ M  +F   ++LE+F+ D+    +  Y+KSE +P KN+ PVKVVVA  F+EIVNDP KDVLIEFYAPWCGHCK L PKY EL ++LS++ +IVIAKMDATANDVP  Y+V                   ++  REV D L ++  EA+S L
Sbjct:  232 NFGICPHLTKENIDQLRKRDLLTAYYDLDYVHNPKGSNYWRN-VMKVASQY--SSRGLLFSVANRKDFEDELEEDYGLGSTEGSEVPFVTIRTRLGHKYSMREEFRDGKSLERFLEDYYANSLKRYIKSEPVPAKNNGPVKVVVADTFEEIVNDPEKDVLIEFYAPWCGHCKKLEPKYTELGQELSSDPNIVIAKMDATANDVPEGYDV------------------HFNGAREVKDFLNFLKREATSSL 460

HSP 2 Score: 156.377 bits (394), Expect = 1.211e-40
Identity = 87/198 (43.94%), Postives = 122/198 (61.62%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAK-VDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            EH  +LV+FYA  CGHCKKLAPE+E AA  LK     + +AK VDCT+ T+ C + GV+GYPTLK+F+NG+ +  Y G RSA GI+  M  ++GP S  L  E++   F    D  VV F +S+S  L + FL  A  + E FRFAHT D  L  K N  + I++F   ++A+KFE++ V + G  S   +R ++ +N
Sbjct:   42 EHETMLVKFYA--CGHCKKLAPEFETAAKRLKGV---VTLAKQVDCTSSTEVCGRFGVTGYPTLKIFRNGRESSSYDGPRSA-GIVDQMKKQAGPDSVPLHNEKDLETFVNHYDASVVVFESSDSPQLVE-FLKGANLMRESFRFAHTTDLQLGLKYNLTSGILLFRPPRLASKFEESVVSHTGPFSVTALRRFIRDN 232

HSP 3 Score: 60.077 bits (144), Expect = 4.950e-9
Identity = 26/43 (60.47%), Postives = 30/43 (69.77%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTA 143
            +L+EFYAPWCGHCKKL P+Y      L   DP I IAK+D TA
Sbjct:  387 VLIEFYAPWCGHCKKLEPKYTELGQEL-SSDPNIVIAKMDATA 428

HSP 4 Score: 51.9878 bits (123), Expect = 1.616e-6
Identity = 45/142 (31.69%), Postives = 76/142 (53.52%), Query Frame = 1

Query: 1744 INDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAK-MDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGRE--VDDMLKYIASEASSPLKN 2157
            ++  L   + V L   S+  ++D  V  +   +FD +  +  + +L++FYA  CGHCK LAP++E  AK+L     + +AK +D T++ +V   + V+G+PT+    +N + S  SY   R   + D +K  A   S PL N
Sbjct:    5 VSGLLSGALFVCLWGGSVSARSD--VVELTDVDFDYVAAE-HETMLVKFYA--CGHCKKLAPEFETAAKRLKGV--VTLAKQVDCTSSTEVCGRFGVTGYPTLKIF-RNGRES-SSYDGPRSAGIVDQMKKQAGPDSVPLHN 137

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: pdia3 (protein disulfide isomerase family A, member 3 [Source:ZFIN;Acc:ZDB-GENE-031002-9])

HSP 1 Score: 274.633 bits (701), Expect = 5.542e-84
Identity = 131/245 (53.47%), Postives = 174/245 (71.02%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSME--NLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +G+  H T  N   F  + L+VA Y+VDY KNPKG+NYWRNR++KVAKKFI+ G ++ +AI+N ++  Q+LS+YG+E        +  +     K+ +  +F+ +  +LE F+ D+   K+  +LKSE IPE ND PVKVVVA+ FDE+VND +KDVLIEFYAPWCGHCK+L PKY ELA KL  + +I+IAKMDATANDVP+ Y+V GFPTIYF+P  SK SPK Y  GREV D + Y+  EA+
Sbjct:  237 LGICPHLTDDNKDLFKGKDLLVAYYDVDYTKNPKGSNYWRNRVMKVAKKFIEEGHTLSYAIANHKDFGQQLSDYGLEHVSGDVPVVAIKKSNGDKYILREEFTRDGKSLENFLQDYFDGKLKKHLKSEPIPEDNDGPVKVVVAEIFDELVNDESKDVLIEFYAPWCGHCKNLEPKYLELADKLKNDPNILIAKMDATANDVPAQYDVRGFPTIYFSPMGSKDSPKKYEGGREVSDFISYLKREAT 481

HSP 2 Score: 209.92 bits (533), Expect = 5.707e-60
Identity = 98/198 (49.49%), Postives = 139/198 (70.20%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDA-SEHQIRTWVEENM 596
            H ++LVEF+APWCGHCK+LAPEYE AAT LK     +A+AKVDCTA T+TC K GVSGYPTLK+F++G+ + DY G R+ADGI+ ++  ++GPSS ELKT E+  KF    DP +VGFF   SSD    F+ VA    +++RFAH+  + +  K   +  IV+F   ++A+KFE+TQV Y  D+ S  +I+ ++++N+
Sbjct:   42 HDMVLVEFFAPWCGHCKRLAPEYEKAATKLKNT---VALAKVDCTANTETCNKFGVSGYPTLKIFRDGELSSDYDGPRTADGIVGFLKKQAGPSSVELKTVEDLEKFVGDNDPSIVGFFKDASSDAQTEFMKVASSQRDNYRFAHSNVQAVLDKQGAEEAIVVFRPLRLASKFEETQVTYAEDSYSSAKIKAFIQDNI 236

HSP 3 Score: 71.633 bits (174), Expect = 3.002e-13
Identity = 36/90 (40.00%), Postives = 55/90 (61.11%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            VL+EF+APWCGHCK LAP+YE+ A KL  ++ + +AK+D TAN +  + + VSG+PT+         S   Y   R  D ++ ++  +A 
Sbjct:   45 VLVEFFAPWCGHCKRLAPEYEKAATKL--KNTVALAKVDCTANTETCNKFGVSGYPTLKIFRDGELSS--DYDGPRTADGIVGFLKKQAG 130

HSP 4 Score: 66.2402 bits (160), Expect = 1.187e-11
Identity = 38/90 (42.22%), Postives = 47/90 (52.22%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYM 266
            E   +L+EFYAPWCGHCK L P+Y   A  L K DP I IAK+D TA      ++ V G+PT+     G       Y G R     I Y+
Sbjct:  389 ESKDVLIEFYAPWCGHCKNLEPKYLELADKL-KNDPNILIAKMDATA-NDVPAQYDVRGFPTIYFSPMGSKDSPKKYEGGREVSDFISYL 476

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: pdia4 (protein disulfide isomerase family A, member 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5493])

HSP 1 Score: 184.882 bits (468), Expect = 5.950e-50
Identity = 101/250 (40.40%), Postives = 153/250 (61.20%), Query Frame = 1

Query: 1411 SMGLAGHRTHSN--VKYFAKRPLIVALYNVDYEKNPK-GTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMI-ADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVP-SPYEVSGFPTIYFAPKNSKHSPKSYSSG-REVDDMLKYIASEAS 2142
            S+ L G R  SN   +Y ++RPL+V  Y VD+  + +  T +WR+++L+VAK F        FAI++  + ++ELS+ G+      +V     D   +K+ M   +F  + L  F+  F + K+   +KS+ +P+ N  PVKVVV + F+++V D +KDVLIEFYAPWCGHCKSL P Y++L KK      +VIAKMDAT ND+P   Y+  GFPTIYF+P  +K  P  ++ G R+++ + K+I   A+
Sbjct:  387 SVPLVGQRKPSNEAKRYASRRPLVVVFYGVDFSFDYRTATQFWRSKVLEVAKDF----PKFTFAIASEDDYSKELSDLGLAESG-EEVNAAILDASGKKYAMAPEEFDADVLRDFVISFEKGKLKAVVKSQPLPKSNKGPVKVVVGRTFEQMVLDNSKDVLIEFYAPWCGHCKSLEPIYKDLGKKYKGHKGLVIAKMDATVNDIPHDSYKAEGFPTIYFSPSGAKDRPIKFADGSRDLESLSKFIEKHAT 631

HSP 2 Score: 176.407 bits (446), Expect = 5.206e-47
Identity = 84/198 (42.42%), Postives = 129/198 (65.15%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVV-GFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLN-YKNNIVIFHSKKMANKFEDTQVKY--KGDASEHQIRTWVEEN 593
            +ILVEFYAPWCGHCKKLAPEYE AA  L K  PPI +AKVD T E++  ++ GVSGYPTLK+F+ G+ A+DY+G R   GI+ +M+ ++GP+S+ELK+ +  N F  + D VV+ G F +E     + F      + E+F+F HTF+E +   L      +V+ H ++  +K+E  Q  +  + D+++  ++ +VE++
Sbjct:  190 IILVEFYAPWCGHCKKLAPEYEKAAQELSKNTPPIPLAKVDATVESELGKRFGVSGYPTLKLFRKGK-AYDYNGPREQYGIVSHMIEQAGPASQELKSMKQLNGFVQNGDDVVILGVFKNEQDVALQLFQETGNNVREEFKFYHTFEENIKNHLKAVDGQVVVLHPERFQSKYEPKQFTFDIQADSTDSDLKAFVEKH 386

HSP 3 Score: 113.235 bits (282), Expect = 3.156e-26
Identity = 58/123 (47.15%), Postives = 75/123 (60.98%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGII---KYMVS---KSGPSSKELKTEENFNKFTASADPVVVGFFT 365
            +L+EFYAPWCGHCK+ A EYE  A  L + DPPI +AKVD T      E+  VSGYPT+K+ K GQ A DY G+R+ D II   K + S   K  P +    TE NF++    AD ++V F+ 
Sbjct:   76 VLLEFYAPWCGHCKEFASEYEKIAKELAENDPPIPVAKVDATVAVHLAERFSVSGYPTIKILKKGQ-AVDYDGDRTQDAIIAKVKEVASPDWKPPPEAVLTLTESNFDEIVNDADIILVEFYA 197

HSP 4 Score: 81.2629 bits (199), Expect = 3.305e-16
Identity = 46/112 (41.07%), Postives = 69/112 (61.61%), Query Frame = 1

Query: 1813 EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            E V  +   NFDEIVND    +L+EFYAPWCGHCK LAP+YE+ A++LS  +  I +AK+DAT  +++   + VSG+PT+    K   +    Y+  RE   ++ ++  +A 
Sbjct:  171 EAVLTLTESNFDEIVND-ADIILVEFYAPWCGHCKKLAPEYEKAAQELSKNTPPIPLAKVDATVESELGKRFGVSGYPTLKLFRKGKAY---DYNGPREQYGIVSHMIEQAG 278

HSP 5 Score: 68.9366 bits (167), Expect = 2.782e-12
Identity = 50/119 (42.02%), Postives = 68/119 (57.14%), Query Frame = 1

Query: 1804 KNDEPVKVVVAKNFDEIVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKLSAESD--IVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
            K +  V ++   NFD  V    KD VL+EFYAPWCGHCK  A +YE++AK+L AE+D  I +AK+DAT A  +   + VSG+PTI    K        Y   R  D ++  +  E +SP
Sbjct:   53 KEENGVLILKDLNFDFFV--AGKDTVLLEFYAPWCGHCKEFASEYEKIAKEL-AENDPPIPVAKVDATVAVHLAERFSVSGYPTIKILKKGQA---VDYDGDRTQDAIIAKV-KEVASP 164

HSP 6 Score: 53.9138 bits (128), Expect = 1.181e-7
Identity = 24/59 (40.68%), Postives = 33/59 (55.93%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK L P Y+      K     + IAK+D T      + +   G+PT+
Sbjct:  541 VLIEFYAPWCGHCKSLEPIYKDLGKKYKGHK-GLVIAKMDATVNDIPHDSYKAEGFPTI 598

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: p4hb (prolyl 4-hydroxylase, beta polypeptide [Source:ZFIN;Acc:ZDB-GENE-080610-1])

HSP 1 Score: 121.709 bits (304), Expect = 6.922e-32
Identity = 67/189 (35.45%), Postives = 107/189 (56.61%), Query Frame = 3

Query:   33 APWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG--QFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            APWCGHCK L PE+  AA  LK +   I + KVD T ET+  +++GV GYPT+K FK+G  + A +Y+  R AD I+ ++  ++GPS+  L       KF  SA+ VVVGFF    ++  K FL  A+ +++      + D+  +     K  +++F       KF++ +  Y+G+ S+  +R +V+ N
Sbjct:    1 APWCGHCKALGPEFAKAAGTLKAEGSAIRLGKVDATEETELAKEYGVRGYPTIKFFKDGDAKNAKEYAAGRQADDIVNWLKKRTGPSATTLDDAAATAKFIESAEVVVVGFFKDVEAEDAKVFLKAADGIDDIAFGLASSDDAFTQYEVSKEGVILFK------KFDEGRNVYEGELSKEGLRKFVKSN 183

HSP 2 Score: 73.1738 bits (178), Expect = 4.176e-15
Identity = 33/80 (41.25%), Postives = 50/80 (62.50%), Query Frame = 1

Query: 1894 APWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            APWCGHCK+L P++ + A  L AE S I + K+DAT   ++   Y V G+PTI F       + K Y++GR+ DD++ ++
Sbjct:    1 APWCGHCKALGPEFAKAAGTLKAEGSAIRLGKVDATEETELAKEYGVRGYPTIKFFKDGDAKNAKEYAAGRQADDIVNWL 80

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002052.1 (pep scaffold:Pmarinus_7.0:GL480798:2613:20969:-1 gene:ENSPMAG00000001848.1 transcript:ENSPMAT00000002052.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.383 bits (272), Expect = 9.622e-26
Identity = 58/130 (44.62%), Postives = 79/130 (60.77%), Query Frame = 1

Query: 1708 IADFSMENLEKFINDFLQEKVPVYLKSESIPEK-NDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSS 2094
             +DF+  N+  F  D+L E    + KS+ IP+  N  PVKV+V KNFDE V D TK+V +EFYA WC HCK LAP +E+L  +     +IVIAKMDA  N+V + + + G+P I + P       +S SS
Sbjct:  283 FSDFTTANITSFCQDYLDEHNKPFSKSQEIPKDWNKRPVKVLVGKNFDEFVFDETKNVFVEFYASWCDHCKKLAPVWEQLGVQYKDHDNIVIAKMDAEKNEVAAVH-IPGYPKIKYFPAGPGKKVRSSSS 411

HSP 2 Score: 57.7658 bits (138), Expect = 4.710e-9
Identity = 41/158 (25.95%), Postives = 69/158 (43.67%), Query Frame = 3

Query:   42 CGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFA--FDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFF-TSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSK 506
            C  C +L P+       L+++  P+ +  +D         +  VS YP   +F  G  A    Y  +R A+ + K+   ++GP +  + T      F  S   V++GFF  +ES DL K FL +A+  +E   F  T  E +  K     + ++   K
Sbjct:    1 CEQCSELPPKLARTVELLRERGAPVRLGSLDGETHATLATEFDVSHYPDFLLFDPGSRAKPRHYHAQREAEALAKWATRRAGPPAVTVATTAEAQAFVDSDSLVLLGFFKDTESRDL-KTFLEIADTYDE-VPFGVTSSEEVFAKYGVSTDSIVLFKK 156

HSP 3 Score: 55.8398 bits (133), Expect = 2.216e-8
Identity = 30/65 (46.15%), Postives = 35/65 (53.85%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG 209
            + VEFYA WC HCKKLAP +E      K  D  I IAK+D  AE        + GYP +K F  G
Sbjct:  340 VFVEFYASWCDHCKKLAPVWEQLGVQYKDHD-NIVIAKMD--AEKNEVAAVHIPGYPKIKYFPAG 401

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Match: TMX3 (thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718])

HSP 1 Score: 103.605 bits (257), Expect = 8.506e-24
Identity = 60/194 (30.93%), Postives = 95/194 (48.97%), Query Frame = 3

Query:    9 SVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEE 590
             V LV+FYAPWCGHCKKL P +   A  +K    P+ + K+D TA +    ++GV GYPT+K+ K G  +++Y G R+ D II +    +GP+ + L T   F    +  D  +   +    S L ++F  VA ++  +  F  T +E L   ++        H    A  F+D       ++ +  + TWV  
Sbjct:   15 GVWLVDFYAPWCGHCKKLEPVWNEVAQEMKASGSPVRVGKLDATAHSGIATEYGVRGYPTIKLIK-GDLSYNYKGPRTKDEIIAFANRVAGPAMRHLSTPALFAHTQSRHD--IFFLYVGGDSKLKESFTQVALEMVVNAYFFSTPEEVLPANVH-------IHEAPAALVFKDGTYYEYDESDDGDLATWVRR 198

HSP 2 Score: 65.0846 bits (157), Expect = 2.552e-11
Identity = 28/58 (48.28%), Postives = 42/58 (72.41%), Query Frame = 1

Query: 1879 LIEFYAPWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDATAN-DVPSPYEVSGFPTI 2046
            L++FYAPWCGHCK L P + E+A+++ A  S + + K+DATA+  + + Y V G+PTI
Sbjct:   18 LVDFYAPWCGHCKKLEPVWNEVAQEMKASGSPVRVGKLDATAHSGIATEYGVRGYPTI 75

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Match: PDI1 (Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication [Source:SGD;Acc:S000000548])

HSP 1 Score: 122.865 bits (307), Expect = 6.278e-30
Identity = 75/198 (37.88%), Postives = 106/198 (53.54%), Query Frame = 1

Query: 1585 HFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLS-AESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGR 2175
             F +  + +M ++L +YG+  P  S+    A DE + K  +      + +E  + DFL+      +KS+ I E  D  V  +V KN DEIVNDP KDVL+ +YAPWCGHCK LAP Y+ELA   + A SD++IAK+D T NDV     + G+PTI   P   K     Y   R +D +  +I         +FD  G+
Sbjct:  310 QFPLFAIHDMTEDL-KYGL--PQLSE---EAFDELSDKIVL----ESKAIESLVKDFLKGDASPIVKSQEIFENQDSSVFQLVGKNHDEIVNDPKKDVLVLYYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHTENDVRGVV-IEGYPTIVLYPGGKKSESVVYQGSRSLDSLFDFIKENG-----HFDVDGK 491

HSP 2 Score: 105.145 bits (261), Expect = 3.970e-24
Identity = 52/145 (35.86%), Postives = 83/145 (57.24%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQF--AFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRF 434
            H ++L EF+APWCGHCK +APEY  AA  L +++  I +A++DCT     C +H + G+P+LK+FKN     + DY G R+A+ I+++M+ +S P+   +     +        PV+V     + +D    F S+A K   D+ F
Sbjct:   49 HDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKN--ITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAVAVVADLPAYLANETFVTPVIVQSGKID-ADFNATFYSMANKHFNDYDF 190

HSP 3 Score: 64.6994 bits (156), Expect = 2.651e-11
Identity = 35/123 (28.46%), Postives = 71/123 (57.72%), Query Frame = 1

Query: 1774 VYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEA 2139
            V+ + E++  ++   VK+    +F+E +      VL EF+APWCGHCK++AP+Y + A+ L  E +I +A++D T N D+   + + GFP++     +  ++   Y   R  + +++++  ++
Sbjct:   20 VFAQQEAVAPEDSAVVKLAT-DSFNEYIQSHDL-VLAEFFAPWCGHCKNMAPEYVKAAETL-VEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQS 139

HSP 4 Score: 62.7734 bits (151), Expect = 1.070e-10
Identity = 31/86 (36.05%), Postives = 46/86 (53.49%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQ--FAFDYSGERSADGIIKYM 266
            +LV +YAPWCGHCK+LAP Y+  A         + IAK+D T          + GYPT+ ++  G+   +  Y G RS D +  ++
Sbjct:  397 VLVLYYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHT--ENDVRGVVIEGYPTIVLYPGGKKSESVVYQGSRSLDSLFDFI 480

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Match: EUG1 (Protein disulfide isomerase of the endoplasmic reticulum lumen; EUG1 has a paralog, PDI1, that arose from the whole genome duplication; function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER [Source:SGD;Acc:S000002926])

HSP 1 Score: 95.9005 bits (237), Expect = 3.685e-21
Identity = 54/152 (35.53%), Postives = 83/152 (54.61%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFD---YSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASAD-PVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFD 449
            H ++LVEF+APWC H + L P  E AA+ LK+ + P  + ++DC A +  C +  ++ YPTLK+FKNG+  FD   Y G +  D I +YM+     S   L +E+    +  +A  PVV+    +  ++ Y+    VA  L ED+ F    D
Sbjct:   50 HPLVLVEFFAPWCLHSQILRPHLEEAASILKEHNVP--VVQIDCEANSMVCLQQTINTYPTLKIFKNGRI-FDGQVYRGVKITDEITQYMIQLYEASVIYLNSEDEIQPYLENATLPVVINRGLTGLNETYQ---EVALDLAEDYVFLSLLD 195

HSP 2 Score: 74.7146 bits (182), Expect = 1.984e-14
Identity = 48/139 (34.53%), Postives = 82/139 (58.99%), Query Frame = 1

Query: 1738 KFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESD----IVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            + + D+ +      +KSE IP++    V  +V K  D+IV+D  KDVL+++YA WC H K  AP YEE+A  L+++      I+IA++D+ AND+ S + V+G+PTI   P  +   P  ++  R ++D+ ++I    +
Sbjct:  350 QLVKDYREGTAKPIVKSEEIPKEQKSNVYKIVGKTHDDIVHDDDKDVLVKYYATWCIHSKRFAPIYEEIANVLASDESVRDKILIAEVDSGANDILS-FPVTGYPTIALYPAGNNSKPIIFNKIRNLEDVFEFIKESGT 487

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Match: MPD1 (Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation [Source:SGD;Acc:S000005814])

HSP 1 Score: 68.5514 bits (166), Expect = 6.155e-13
Identity = 40/136 (29.41%), Postives = 66/136 (48.53%), Query Frame = 1

Query: 1807 NDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAND-VPSPYEVSGFPTIY-FAPKN--------------SKHSPKSYSSGREVDDMLKYIASEASSPLKNFDR 2166
            +D  +  +  K+FD+ +++     L+EFYAPWCGHCK L+  + + AK+L     +     D   N  + + Y+V+GFPT+  F P                S H+ + YS  R +  ++ +  S   S +K F R
Sbjct:   27 SDPHISELTPKSFDKAIHNTNYTSLVEFYAPWCGHCKKLSSTFRKAAKRLDGVVQVAAVNCDLNKNKALCAKYDVNGFPTLMVFRPPKIDLSKPIDNAKKSFSAHANEVYSGARTLAPIVDFSLSRIRSYVKKFVR 162

HSP 2 Score: 68.1662 bits (165), Expect = 8.015e-13
Identity = 39/105 (37.14%), Postives = 56/105 (53.33%), Query Frame = 3

Query:   18 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDC--TAETKTCEKHGVSGYPTLKVFK-----------NGQFAFD------YSGERSADGIIKYMVSK 275
            LVEFYAPWCGHCKKL+  +  AA   K+ D  + +A V+C        C K+ V+G+PTL VF+           N + +F       YSG R+   I+ + +S+
Sbjct:   51 LVEFYAPWCGHCKKLSSTFRKAA---KRLDGVVQVAAVNCDLNKNKALCAKYDVNGFPTLMVFRPPKIDLSKPIDNAKKSFSAHANEVYSGARTLAPIVDFSLSR 152

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Match: TRX1 (Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication [Source:SGD;Acc:S000004033])

HSP 1 Score: 52.373 bits (124), Expect = 6.887e-9
Identity = 26/70 (37.14%), Postives = 38/70 (54.29%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQ 212
            +  +++V+FYA WCG CK +AP  E       +Q P     K+D        +K+ VS  PTL +FKNG+
Sbjct:   17 QDKLVVVDFYATWCGPCKMIAPMIE----KFSEQYPQADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGK 82

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Match: TRX2 (Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000003441])

HSP 1 Score: 51.2174 bits (121), Expect = 1.662e-8
Identity = 31/92 (33.70%), Postives = 45/92 (48.91%), Query Frame = 1

Query: 1834 AKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDA-TANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREV 2106
            A  +D  +    K V+++F+A WCG CK +AP  E+ A++    SD    K+D    +DV    EVS  PT+ F           Y  G+EV
Sbjct:    8 ASEYDSALASGDKLVVVDFFATWCGPCKMIAPMIEKFAEQY---SDAAFYKLDVDEVSDVAQKAEVSSMPTLIF-----------YKGGKEV 85

HSP 2 Score: 44.2838 bits (103), Expect = 4.517e-6
Identity = 23/67 (34.33%), Postives = 35/67 (52.24%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQ 212
            +++V+F+A WCG CK +AP  E       +Q    A  K+D    +   +K  VS  PTL  +K G+
Sbjct:   21 LVVVDFFATWCGPCKMIAPMIE----KFAEQYSDAAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGK 83

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO31634 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXD7])

HSP 1 Score: 246.514 bits (628), Expect = 2.654e-73
Identity = 124/245 (50.61%), Postives = 166/245 (67.76%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            G  G RT  N + F K PL V  ++VD++KN KG+ YWRNR+LKV K F D  K+++FAI++  +  + LS+ G+   D +       ++   KF M   FS+++ ++F+ D+    +  ++KSE +PE ND PVKVVV +NF EIVNDPTKDVLIEFYAPWCGHCKSL PKY EL +KL    DIVIAKMDATAND P  + V GFPTIY+AP N+K +P+ Y  GREV D + +I  +A+ P+
Sbjct:  234 GRVGQRTPDNEEQFPK-PLCVVFFDVDWKKNAKGSKYWRNRVLKVTKFFDD--KAMNFAIASFSDYERVLSDIGVT--DKANPSAVVYNDAGDKFLMKEKFSVDSFKQFLEDYFAGSLKPHIKSEPLPESNDGPVKVVVGENFKEIVNDPTKDVLIEFYAPWCGHCKSLEPKYNELGEKLQDVKDIVIAKMDATANDAPPNFSVQGFPTIYWAPANNKENPEKYEGGREVSDFVDFIKRKATKPV 473

HSP 2 Score: 192.971 bits (489), Expect = 9.455e-54
Identity = 94/193 (48.70%), Postives = 128/193 (66.32%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETK-TCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADP-VVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWV 584
            ++LVEF+APWCGHCK+LAPEYE AA ALKK DPP+ +AKVDCT   K TC K+GVSGYPTLK+F+NG+ + DY G R + GII+YM  ++GPSS E+K+ ++  K    A+  VVVGF   +  DL  AF+  A ++ + F FAH     +  K NYKN IV+F  K +  K E + + Y G   +  I+ ++
Sbjct:   37 IMLVEFFAPWCGHCKRLAPEYETAAEALKKNDPPVPLAKVDCTEAGKDTCSKYGVSGYPTLKIFRNGEMSKDYDGPRDSSGIIRYMKKQAGPSSVEIKSVDHLEKKLDDAESNVVVGFLDGD-DDLKNAFMRTANEMRDSFSFAHASVTDVLEKYNYKNQIVVFRPKHLHTKLEPSFIAYTGSPDDFYIKKFI 228

HSP 3 Score: 69.3218 bits (168), Expect = 2.341e-12
Identity = 37/92 (40.22%), Postives = 56/92 (60.87%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDAT--ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EF+APWCGHCK LAP+YE  A+ L   +  + +AK+D T    D  S Y VSG+PT+    +N + S K Y   R+   +++Y+  +A 
Sbjct:   38 MLVEFFAPWCGHCKRLAPEYETAAEALKKNDPPVPLAKVDCTEAGKDTCSKYGVSGYPTLKIF-RNGEMS-KDYDGPRDSSGIIRYMKKQAG 127

HSP 4 Score: 55.8398 bits (133), Expect = 3.736e-8
Identity = 28/60 (46.67%), Postives = 36/60 (60.00%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEY-EIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCK L P+Y E+       +D  I IAK+D TA         V G+PT+
Sbjct:  382 VLIEFYAPWCGHCKSLEPKYNELGEKLQDVKD--IVIAKMDATA-NDAPPNFSVQGFPTI 438

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO32930 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STM8])

HSP 1 Score: 214.542 bits (545), Expect = 4.265e-60
Identity = 112/262 (42.75%), Postives = 165/262 (62.98%), Query Frame = 1

Query: 1378 ISNYEIDNCILSMGLAGHRTHSNVKYFAKRPLIVALYNVDYE-KNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIAD---FSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            +  +  D  +  +GL  + ++   K +A RPL +  Y VD+   N   T +WR+++++VAK   D    I FAI+N +E  QEL ++G+ +    +V +   D+  +KF+M  D   FS ++L +F+ +F    +   +KS+ +P+ N EPV VVV K FDEIVNDP KDVLIEFYAPWCGHCK+L P +++L K    + +IVIAK+DATANDVPS Y V GFPTIYFA    K +P  +  GRE+ D++K++  +A+  L
Sbjct:  383 LQGFYKDKRVPLVGL--YTSYDKDKKYAARPLCIVYYGVDFGFDNRVATQFWRSKVIEVAKDHRD----ITFAIANEEESEQELKDFGL-AESGEEVNVGCFDKEGRKFRMDPDEEEFSEDSLREFVEEFKAGNLKPIIKSQPVPKSNKEPVTVVVGKTFDEIVNDPKKDVLIEFYAPWCGHCKALEPTFKKLGKHFRNDKNIVIAKIDATANDVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKFVEEKATVSL 637

HSP 2 Score: 159.844 bits (403), Expect = 3.690e-41
Identity = 80/184 (43.48%), Postives = 115/184 (62.50%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPV-VVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNY-KNNIVIFHSKKMANKFEDTQVKYKG 551
             S++LVEF+APWCGHCK+LAPEYE AA  L+K DPPI +A VD T E++  +K+ V GYPTLKVF+ G+ A +Y G+R   GI  YM S+ GPSS+ L + +    F    D V ++GFF  E   + +++L     + +D+ FAHTFD          K++IV+F  ++  +K+E     Y+G
Sbjct:  193 ESLMLVEFFAPWCGHCKQLAPEYEKAAQELQKNDPPIPLAIVDATIESELAQKYEVQGYPTLKVFRKGK-ATEYKGQRDQYGIASYMRSQVGPSSRILSSLKAVQDFMKEKDDVTIMGFFDGEDDKMLESYLEANNDVRDDYPFAHTFDAAAKKHFGIKKSSIVLFQPERFLSKYEPKHFVYEG 375

HSP 3 Score: 119.783 bits (299), Expect = 4.851e-28
Identity = 72/209 (34.45%), Postives = 112/209 (53.59%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELK------TEENFNKFTASADPVVVGFFT---SESSDLYKAFLSVAEKL--NEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            E+++ILVEFYAPWCGHCK LAPEY  AA  +K  DPP+  AK+D T  +   ++  VSGYPTLK+F+ G   ++Y G R   GI++YM  +S P+ K         T+ENF +       ++V FF         L   +   A++L  N+        D T+ ++L  K  +  + + K+  K + T+  YKG   ++ I +++   +
Sbjct:   77 ENNIILVEFYAPWCGHCKSLAPEYAKAAKKMKLNDPPVPFAKMDATVASDIAQRFDVSGYPTLKIFRKGT-PYEYEGPREESGIVEYMKKQSDPNWKPPPVAALTLTKENFTEVVNRESLMLVEFFAPWCGHCKQLAPEYEKAAQELQKNDPPIPLAIVDATIESELAQKYEVQGYPTLKVFRKGKATE--YKGQRDQYGIASYMRSQV 282

HSP 4 Score: 86.2705 bits (212), Expect = 1.753e-17
Identity = 48/120 (40.00%), Postives = 77/120 (64.17%), Query Frame = 1

Query: 1786 SESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDAT-ANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEA 2139
            S+ + E++D  V V+ +KNFD ++ +    +L+EFYAPWCGHCKSLAP+Y + AKK+   +  +  AKMDAT A+D+   ++VSG+PT+       K +P  Y   RE   +++Y+  ++
Sbjct:   54 SDEVKEEDD--VLVLNSKNFDRVIEE-NNIILVEFYAPWCGHCKSLAPEYAKAAKKMKLNDPPVPFAKMDATVASDIAQRFDVSGYPTLKIF---RKGTPYEYEGPREESGIVEYMKKQS 167

HSP 5 Score: 73.1738 bits (178), Expect = 2.095e-13
Identity = 40/94 (42.55%), Postives = 61/94 (64.89%), Query Frame = 1

Query: 1777 YLKSESIPEKNDEPVK--VVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSA-ESDIVIAKMDAT-ANDVPSPYEVSGFPTI 2046
            Y+K +S P     PV    +  +NF E+VN  +  +L+EF+APWCGHCK LAP+YE+ A++L   +  I +A +DAT  +++   YEV G+PT+
Sbjct:  162 YMKKQSDPNWKPPPVAALTLTKENFTEVVNRESL-MLVEFFAPWCGHCKQLAPEYEKAAQELQKNDPPIPLAIVDATIESELAQKYEVQGYPTL 254

HSP 6 Score: 60.4622 bits (145), Expect = 1.669e-9
Identity = 37/102 (36.27%), Postives = 54/102 (52.94%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL--KVFKNGQFAFDYSGERSADGIIKYMVSKSGPS-SKELKTEE 311
            +L+EFYAPWCGHCK L P ++       + D  I IAK+D TA       + V G+PT+     K+ +    + G R    +IK++  K+  S SKE   +E
Sbjct:  546 VLIEFYAPWCGHCKALEPTFKKLGKHF-RNDKNIVIAKIDATA-NDVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKFVEEKATVSLSKEKAKDE 645

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO33843 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR22])

HSP 1 Score: 159.844 bits (403), Expect = 1.028e-45
Identity = 72/124 (58.06%), Postives = 92/124 (74.19%), Query Frame = 1

Query: 1780 LKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            +KS+ +P+ N EPV VVV K FDEIVNDP KDVLIEFYAPWCGHCK+L P +++L K    + +IVIAK+DATANDVPS Y V GFPTIYFA    K +P  +  GRE+ D++K++  +A+  L
Sbjct:   16 VKSQPVPKSNKEPVTVVVGKTFDEIVNDPKKDVLIEFYAPWCGHCKALEPTFKKLGKHFRNDKNIVIAKIDATANDVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKFVEEKATVSL 139

HSP 2 Score: 60.4622 bits (145), Expect = 8.443e-11
Identity = 37/102 (36.27%), Postives = 54/102 (52.94%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL--KVFKNGQFAFDYSGERSADGIIKYMVSKSGPS-SKELKTEE 311
            +L+EFYAPWCGHCK L P ++       + D  I IAK+D TA       + V G+PT+     K+ +    + G R    +IK++  K+  S SKE   +E
Sbjct:   48 VLIEFYAPWCGHCKALEPTFKKLGKHF-RNDKNIVIAKIDATA-NDVPSTYAVEGFPTIYFATSKDKKNPIKFDGGRELKDLIKFVEEKATVSLSKEKAKDE 147

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO36830 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHH5])

HSP 1 Score: 142.895 bits (359), Expect = 2.623e-36
Identity = 82/195 (42.05%), Postives = 121/195 (62.05%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN-IVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            +LVEFYAPWCGHCK LAPEY  AA  LK +   I +AKVD TAETK  EK  V GYPT+K FK+G+ + +Y+G R+A  I+ ++  K+GP +K+L T +    F  + +  VVGFFT + SD  KAFLS A+ ++ D  F    D+ ++++   + + IV+F       KF++ +  Y G+    +I+ +V+ N 
Sbjct:   44 VLVEFYAPWCGHCKALAPEYAKAAGQLKSEKSEIKLAKVDATAETKLGEKFQVQGYPTIKFFKDGKPS-EYAGGRTAPEIVSWLNKKTGPPAKDLATADAMKDFI-TKEVAVVGFFTDKESDAAKAFLSAADGID-DVEFGIVSDKAIASEHKVEGDKIVLF------KKFDEGRNDYDGEYDFEKIQQFVKANQ 229

HSP 2 Score: 139.043 bits (349), Expect = 5.702e-35
Identity = 78/191 (40.84%), Postives = 119/191 (62.30%), Query Frame = 1

Query: 1573 GKSIHFAISNVQEMNQELSEY-GIESPDFSKV-YITARDERNQKFK-MIADFSMENLEKFINDFLQEKVPVYLKSESIPEKND-EPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIAS 2133
            GK +   ++   E NQ + E+ GI+S +   +  I   D+   K+K   A+ + EN+++F+  FL +K+  +L S  IPE  D +PVKV+  KNFDE+  +  K+V +EFYAPWCGHCK LAP +++L +K    +DIV+AKMD+TAN+V    +V  FPTI + PK  +     Y+ GR +DD +K++ S
Sbjct:  280 GKVLFVYVNTEVEDNQRIVEFFGIQSSELPTIRLINLADDDMTKYKPTAAEITSENVKEFVQAFLDKKLKPHLLSAEIPEDWDSKPVKVLCGKNFDEVARNKDKNVFVEFYAPWCGHCKQLAPIWDQLGEKYKDHADIVVAKMDSTANEVEG-VKVHSFPTIKYFPKEGEAV--DYNGGRTLDDFVKFLES 467

HSP 3 Score: 95.5153 bits (236), Expect = 1.030e-20
Identity = 56/127 (44.09%), Postives = 80/127 (62.99%), Query Frame = 1

Query: 1786 SESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAE-SDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNF 2160
            SE I E+ D  V V+  KNFDE V    K VL+EFYAPWCGHCK+LAP+Y + A +L +E S+I +AK+DATA   +   ++V G+PTI F  K+ K  P  Y+ GR   +++ ++  +   P K+ 
Sbjct:   17 SEEIKEEED--VLVLTEKNFDEAVA-ANKHVLVEFYAPWCGHCKALAPEYAKAAGQLKSEKSEIKLAKVDATAETKLGEKFQVQGYPTIKFF-KDGK--PSEYAGGRTAPEIVSWLNKKTGPPAKDL 137

HSP 4 Score: 69.3218 bits (168), Expect = 2.343e-12
Identity = 36/86 (41.86%), Postives = 49/86 (56.98%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVS 272
            + VEFYAPWCGHCK+LAP ++      K     I +AK+D TA     E   V  +PT+K F     A DY+G R+ D  +K++ S
Sbjct:  385 VFVEFYAPWCGHCKQLAPIWDQLGEKYKDH-ADIVVAKMDSTA--NEVEGVKVHSFPTIKYFPKEGEAVDYNGGRTLDDFVKFLES 467

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Match: EDO47340 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMG9])

HSP 1 Score: 110.923 bits (276), Expect = 2.771e-26
Identity = 50/97 (51.55%), Postives = 71/97 (73.20%), Query Frame = 1

Query: 1840 NFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI 2127
            NFDE+VN   K  L+EFYAPWCGHCK LAP YE+L +  +  SD++IAK+DA  + D+ S ++V GFPTI + PK S  +P+ Y+ GR+++D +K+I
Sbjct:   31 NFDEVVNGE-KFALVEFYAPWCGHCKQLAPTYEQLGEAYTQSSDVIIAKVDADGDRDLGSRFDVKGFPTIKYFPKGST-TPEEYNGGRDINDFIKFI 125

HSP 2 Score: 98.5969 bits (244), Expect = 3.172e-22
Identity = 55/138 (39.86%), Postives = 82/138 (59.42%), Query Frame = 1

Query: 1744 INDFL---QEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAND-VPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASS 2145
            INDF+   +EK  V  +   IP      V  +   NFD+IV +P  +VL+EF+APWCGHCK+LAP YE++ +    E + VIAK+DA A+  +   Y VSG+PT+ F  K +K   + YSSGR+    + ++  +  +
Sbjct:  118 INDFIKFIEEKTGVRGRVPVIPS----AVADLDESNFDKIVKNPDNNVLVEFFAPWCGHCKNLAPVYEKVGEAFKNEPNCVIAKVDADAHSALGQKYGVSGYPTLKFFSKTNKDG-EEYSSGRDEQSFVDFMNEKCGT 250

HSP 3 Score: 87.0409 bits (214), Expect = 2.496e-18
Identity = 44/90 (48.89%), Postives = 54/90 (60.00%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFAFDYSGERSADGIIKYMVSKSG 281
            +LVEF+APWCGHCK LAP YE    A K + P   IAKVD  A +   +K+GVSGYPTLK F K  +   +YS  R     + +M  K G
Sbjct:  161 VLVEFFAPWCGHCKNLAPVYEKVGEAFKNE-PNCVIAKVDADAHSALGQKYGVSGYPTLKFFSKTNKDGEEYSSGRDEQSFVDFMNEKCG 249

HSP 4 Score: 83.5741 bits (205), Expect = 3.087e-17
Identity = 54/147 (36.73%), Postives = 73/147 (49.66%), Query Frame = 3

Query:   18 LVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFA-FDYSGERSADGIIKYMVSKSG--------PSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFR 431
            LVEFYAPWCGHCK+LAP YE    A   Q   + IAKVD   +     +  V G+PT+K F  G     +Y+G R  +  IK++  K+G        PS+     E NF+K   + D  V+  F +      K    V EK+ E F+
Sbjct:   43 LVEFYAPWCGHCKQLAPTYEQLGEAY-TQSSDVIIAKVDADGDRDLGSRFDVKGFPTIKYFPKGSTTPEEYNGGRDINDFIKFIEEKTGVRGRVPVIPSAVADLDESNFDKIVKNPDNNVLVEFFAPWCGHCKNLAPVYEKVGEAFK 188

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia3 (protein disulfide isomerase family A member 3 [Source:NCBI gene;Acc:101164975])

HSP 1 Score: 292.738 bits (748), Expect = 3.185e-90
Identity = 138/248 (55.65%), Postives = 176/248 (70.97%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMEN--LEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
             G+  H T  N      + L+VA Y VDY+KNPKG+NYWRNR++KVAK F+D GK ++FA++N    + E+SE+G+ S       +  R  +  K+ M  +FS +   LE+F+ D+   K+  YLKSE IPE ND PVKV+VA+NFD IVND +KDVLIEFYAPWCGHCK+L PKY EL +KL+ + ++VIAKMDATANDVPSPYEVSGFPTIYF+P   K SPK Y  GREV D + Y+  EAS+PL
Sbjct:  229 FGICPHMTDDNKDQLKGKDLLVAYYEVDYDKNPKGSNYWRNRVMKVAKSFLDQGKKLNFAVANKNTFSHEVSEFGLSSSSGELPVVAIRTSKGDKYVMTEEFSRDGKALERFLQDYFDGKLKRYLKSEPIPEDNDGPVKVLVAENFDSIVNDDSKDVLIEFYAPWCGHCKNLEPKYNELGEKLANDPNVVIAKMDATANDVPSPYEVSGFPTIYFSPAGRKTSPKKYEGGREVSDFISYLKREASNPL 476

HSP 2 Score: 189.119 bits (479), Expect = 7.828e-52
Identity = 94/200 (47.00%), Postives = 135/200 (67.50%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETL--STKLNYKNNIVIFHSKKMANKFEDTQVKYKGDA-SEHQIRTWVEENM 596
            H + LVEF+APWCGHCK+LAPEYE AAT LK   P   + KVDCTA +  C K+GVSGYPTLK+F++G+ +  Y G RSADGI+ ++  ++GP+S ELKT+ +F KF    D  VVGFF  +S+   + FL  A  L +D+RFAHT  E L  S  ++ +  +V+F   ++ NKFE+  VK+  D  + ++I+ +++EN+
Sbjct:   34 HDLALVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LVKVDCTANSNICSKYGVSGYPTLKIFRDGEESGPYDGPRSADGIVSFLKKQAGPASVELKTDADFEKFIGDQDASVVGFFADQSTSQAE-FLKAASALRDDYRFAHTNSEALLKSNGID-EEGVVLFRPPRLNNKFEENSVKFTEDKFTSNKIKKFIQENI 228

HSP 3 Score: 71.633 bits (174), Expect = 1.190e-12
Identity = 35/90 (38.89%), Postives = 53/90 (58.89%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
             L+EF+APWCGHCK LAP+YE  A +L  +  + + K+D TAN ++ S Y VSG+PT+       +  P  Y   R  D ++ ++  +A 
Sbjct:   37 ALVEFFAPWCGHCKRLAPEYEAAATRL--KGIVPLVKVDCTANSNICSKYGVSGYPTLKIFRDGEESGP--YDGPRSADGIVSFLKKQAG 122

HSP 4 Score: 65.0846 bits (157), Expect = 1.391e-10
Identity = 35/86 (40.70%), Postives = 45/86 (52.33%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAF--DYSGERSADGIIKYM 266
            +L+EFYAPWCGHCK L P+Y      L   DP + IAK+D TA       + VSG+PT+     G+      Y G R     I Y+
Sbjct:  385 VLIEFYAPWCGHCKNLEPKYNELGEKL-ANDPNVVIAKMDATA-NDVPSPYEVSGFPTIYFSPAGRKTSPKKYEGGREVSDFISYL 468

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia8 (protein disulfide-isomerase A3 [Source:NCBI gene;Acc:101165241])

HSP 1 Score: 217.238 bits (552), Expect = 1.566e-62
Identity = 110/249 (44.18%), Postives = 162/249 (65.06%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSM--ENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            GL  H T  N      R L+ A Y++DY+ N +G+NYWRNR++KVA K+  +G+S+ F+++N ++   EL E Y + + D   + ++T R +  QK+ M  +F+   ++LE+F+ D+   ++  Y+KSE IPEKN   VKVVVA++F+EIVNDP KDVLI+FY+P C HCK L P Y ELA+ L ++   VIAKM+A  ND+P  Y+V G+PTIY AP   K +P  Y   RE+ + L ++  E+S  L
Sbjct:  194 GLCPHMTLENRDRLRVRDLLTAYYDLDYQHNVRGSNYWRNRVMKVASKY--AGRSLMFSVANKKDFLMELEEDYDLGTSDAGDMPFVTIRTKLGQKYVMREEFTRDGQSLERFLEDYFAGRLKQYIKSEPIPEKNSAAVKVVVAESFNEIVNDPDKDVLIQFYSPSCPHCKKLEPIYRELAETLYSDPHTVIAKMNAVDNDIPLGYDVQGYPTIYLAPAGRKDNPIRYQGPRELKEFLNFLKRESSHKL 440

HSP 2 Score: 162.925 bits (411), Expect = 5.004e-43
Identity = 80/195 (41.03%), Postives = 121/195 (62.05%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN-IVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            +LV+FYAPWCGHCKKLAPE+E AA  LK     + +AKVDCTA ++TC + GV+GYPTLK+F+ G+ +  Y G R+ADGI + M  ++GP S  LK++E+   F  + D  +VG F S        FL  A  L + FRFAH  D  ++   N  +  +++F   ++A+ FED+ V +K   +   +R ++ +++
Sbjct:    1 MLVKFYAPWCGHCKKLAPEFEKAAKKLKGI---VKLAKVDCTANSETCGRFGVTGYPTLKIFRYGKDSASYDGPRTADGIYEVMRRQTGPDSVHLKSKEDLQAFVNNYDASIVGVFPSSEGSRLPEFLKAAGLLRDQFRFAHITDLQVADDHNVDSECVLLFRPPRLASAFEDSVVVFKDYLTISSLRRFLRDHL 192

HSP 3 Score: 66.6254 bits (161), Expect = 4.813e-11
Identity = 29/58 (50.00%), Postives = 44/58 (75.86%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTI 2046
            +L++FYAPWCGHCK LAP++E+ AKKL  +  + +AK+D TAN +    + V+G+PT+
Sbjct:    1 MLVKFYAPWCGHCKKLAPEFEKAAKKL--KGIVKLAKVDCTANSETCGRFGVTGYPTL 56

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia8 (protein disulfide-isomerase A3 [Source:NCBI gene;Acc:101165241])

HSP 1 Score: 217.238 bits (552), Expect = 4.249e-62
Identity = 110/249 (44.18%), Postives = 162/249 (65.06%), Query Frame = 1

Query: 1417 GLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSE-YGIESPDFSKV-YITARDERNQKFKMIADFSM--ENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPL 2151
            GL  H T  N      R L+ A Y++DY+ N +G+NYWRNR++KVA K+  +G+S+ F+++N ++   EL E Y + + D   + ++T R +  QK+ M  +F+   ++LE+F+ D+   ++  Y+KSE IPEKN   VKVVVA++F+EIVNDP KDVLI+FY+P C HCK L P Y ELA+ L ++   VIAKM+A  ND+P  Y+V G+PTIY AP   K +P  Y   RE+ + L ++  E+S  L
Sbjct:  239 GLCPHMTLENRDRLRVRDLLTAYYDLDYQHNVRGSNYWRNRVMKVASKY--AGRSLMFSVANKKDFLMELEEDYDLGTSDAGDMPFVTIRTKLGQKYVMREEFTRDGQSLERFLEDYFAGRLKQYIKSEPIPEKNSAAVKVVVAESFNEIVNDPDKDVLIQFYSPSCPHCKKLEPIYRELAETLYSDPHTVIAKMNAVDNDIPLGYDVQGYPTIYLAPAGRKDNPIRYQGPRELKEFLNFLKRESSHKL 485

HSP 2 Score: 167.548 bits (423), Expect = 2.528e-44
Identity = 82/199 (41.21%), Postives = 123/199 (61.81%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN-IVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EH  +LV+FYAPWCGHCKKLAPE+E AA  LK     + +AKVDCTA ++TC + GV+GYPTLK+F+ G+ +  Y G R+ADGI + M  ++GP S  LK++E+   F  + D  +VG F S        FL  A  L + FRFAH  D  ++   N  +  +++F   ++A+ FED+ V +K   +   +R ++ +++
Sbjct:   42 EHETMLVKFYAPWCGHCKKLAPEFEKAAKKLKGI---VKLAKVDCTANSETCGRFGVTGYPTLKIFRYGKDSASYDGPRTADGIYEVMRRQTGPDSVHLKSKEDLQAFVNNYDASIVGVFPSSEGSRLPEFLKAAGLLRDQFRFAHITDLQVADDHNVDSECVLLFRPPRLASAFEDSVVVFKDYLTISSLRRFLRDHL 237

HSP 3 Score: 66.2402 bits (160), Expect = 6.315e-11
Identity = 29/58 (50.00%), Postives = 44/58 (75.86%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATAN-DVPSPYEVSGFPTI 2046
            +L++FYAPWCGHCK LAP++E+ AKKL  +  + +AK+D TAN +    + V+G+PT+
Sbjct:   46 MLVKFYAPWCGHCKKLAPEFEKAAKKL--KGIVKLAKVDCTANSETCGRFGVTGYPTL 101

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia4 (protein disulfide isomerase family A member 4 [Source:NCBI gene;Acc:101168751])

HSP 1 Score: 194.512 bits (493), Expect = 1.178e-52
Identity = 112/249 (44.98%), Postives = 150/249 (60.24%), Query Frame = 1

Query: 1411 SMGLAGHRTHSN-VKYFAKRPLIVALYNVDYEKN-PKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIAD-FSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSP-YEVSGFPTIYFAPKNSKHSPKSYSSG-REVDDMLKYIASEAS 2142
            S+ L GHR  SN  K ++KRP++V  Y VD+  +  K T +WR+++L+VAK F +      FAI++ ++   EL   G+ S    +V      E  +KF M  D F  E L  F+  F + K+   +KS+ +P+ N  PVKVVV K FDEIV D  KDVLIEFYAPWCGHCK L P Y  L KK   E ++VIAKMDATAND+P+  Y+  GFPTIY AP N K SP  +  G R V+ +  ++   A+
Sbjct:  389 SIPLVGHRKPSNDAKRYSKRPMVVVYYGVDFSFDYKKATQFWRSKVLEVAKDFPE----YTFAIADEEDYADELKSLGL-SDSGEEVNAGIMAEGGKKFAMEPDDFDSEVLRDFVMAFKKGKLKPIIKSQPVPKSNTGPVKVVVGKTFDEIVMDTQKDVLIEFYAPWCGHCKKLEPDYLSLGKKYKKEKNLVIAKMDATANDIPNDNYKAEGFPTIYLAPANGKQSPVKFEGGDRTVEALSNFLEKHAT 632

HSP 2 Score: 158.688 bits (400), Expect = 2.487e-40
Identity = 76/174 (43.68%), Postives = 112/174 (64.37%), Query Frame = 3

Query:   12 VILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASA-DPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYK-NNIVIFHSKKMANKFE 527
            +ILVEFYAPWCGHCK+LAPEYE AA  L K+ PPI +AKVD T ET+  +++GV+G+PTLK+F+ G+ AF+Y+G R   GI+++M  ++GP SK+++  +   +      D V+VG F++E    Y+ +      L EDF F H+F   ++  L      IVI   +K  +K+E
Sbjct:  192 IILVEFYAPWCGHCKRLAPEYEKAAKELSKRTPPIPLAKVDATVETELAKRYGVNGFPTLKIFRKGR-AFEYNGPRENYGIVEHMGEQAGPPSKQVQAVKQVQELIKDGDDAVIVGIFSNEQDSAYELYTEACNTLREDFSFRHSFSSDVAKLLKASPGQIVIVQPEKFRSKYE 364

HSP 3 Score: 115.546 bits (288), Expect = 2.848e-26
Identity = 56/122 (45.90%), Postives = 76/122 (62.30%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVS------KSGPSSKELKTEENFNKFTASADPVVVGFF 362
            +LVEFYAPWCGHCK+ APEYE  A  LK  DPPI +AKVD T  ++   K  VSGYPT+K+ KNG+   DY G R+   I++ +        K  P +  + T+ENF+    +AD ++V F+
Sbjct:   78 VLVEFYAPWCGHCKQFAPEYEKIAQTLKDNDPPIPVAKVDATQASQLASKFDVSGYPTIKILKNGE-PVDYDGARTEKAIVERVKEVAHPDWKPPPDATLVLTQENFDDTVNNADIILVEFY 198

HSP 4 Score: 81.6481 bits (200), Expect = 1.475e-15
Identity = 46/113 (40.71%), Postives = 69/113 (61.06%), Query Frame = 1

Query: 1825 VVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKN 2157
            V+  +NFD+ VN+    +L+EFYAPWCGHCK LAP+YE+ AK+LS  +  I +AK+DAT   ++   Y V+GFPT+    K        Y+  RE   +++++  +A  P K 
Sbjct:  177 VLTQENFDDTVNN-ADIILVEFYAPWCGHCKRLAPEYEKAAKELSKRTPPIPLAKVDATVETELAKRYGVNGFPTLKIFRKGRAF---EYNGPRENYGIVEHMGEQAGPPSKQ 285

HSP 5 Score: 73.9442 bits (180), Expect = 3.458e-13
Identity = 40/79 (50.63%), Postives = 55/79 (69.62%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SAESDIVIAKMDAT-ANDVPSPYEVSGFPTI 2046
            V V+   NFD  +    KD VL+EFYAPWCGHCK  AP+YE++A+ L   +  I +AK+DAT A+ + S ++VSG+PTI
Sbjct:   60 VLVLTDNNFDTFME--GKDTVLVEFYAPWCGHCKQFAPEYEKIAQTLKDNDPPIPVAKVDATQASQLASKFDVSGYPTI 136

HSP 6 Score: 60.4622 bits (145), Expect = 4.635e-9
Identity = 27/59 (45.76%), Postives = 37/59 (62.71%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTL 191
            +L+EFYAPWCGHCKKL P+Y       KK+   + IAK+D TA     + +   G+PT+
Sbjct:  542 VLIEFYAPWCGHCKKLEPDYLSLGKKYKKEK-NLVIAKMDATANDIPNDNYKAEGFPTI 599

[Close]

BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Match: pdia2 (protein disulfide-isomerase [Source:NCBI gene;Acc:101164281])

HSP 1 Score: 142.124 bits (357), Expect = 7.788e-36
Identity = 77/201 (38.31%), Postives = 124/201 (61.69%), Query Frame = 1

Query: 1549 VAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDE-PVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
            VA++F   GK ++  I     ++  L+ +G+   D   V +   D + +KFK+ ++ ++++L +   + + +    YL+SE IPE  D+ PVKV+VAKNF+ +  DPTK+V +EFYAPWCGHCK LAP +E+L +  +   DI+IAKMDATAN+V S   + GFPT+ + P   K    SY+  R+++ + K++ +    P
Sbjct:  214 VAREF--KGKVLYILIDMTTAVSHVLNYFGVLEKDSPTVRMINMDTQ-KKFKIASEMTIDSLRQLSQEVVDDTAEPYLRSEEIPEDWDKGPVKVLVAKNFETVAMDPTKNVFVEFYAPWCGHCKELAPIWEQLGEIYADHDDIIIAKMDATANEVES-VAIDGFPTLKYFPAGDKEVI-SYTGNRDLETLSKFLDNGGVLP 409

HSP 2 Score: 70.4774 bits (171), Expect = 2.612e-12
Identity = 36/85 (42.35%), Postives = 48/85 (56.47%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNG-QFAFDYSGERSADGIIKYM 266
            + VEFYAPWCGHCK+LAP +E         D  I IAK+D TA     E   + G+PTLK F  G +    Y+G R  + + K++
Sbjct:  321 VFVEFYAPWCGHCKELAPIWEQLGEIYADHD-DIIIAKMDATA--NEVESVAIDGFPTLKYFPAGDKEVISYTGNRDLETLSKFL 402

HSP 3 Score: 70.4774 bits (171), Expect = 2.928e-12
Identity = 49/170 (28.82%), Postives = 88/170 (51.76%), Query Frame = 3

Query:   93 LKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQF--AFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFD-ETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            LK++   + +AKVD   E +  E+  V  +PT+K+F NG      +Y+G+R+  GI++++  +SGP + +L + ++  +F  + +  VVGFF +  S+    F  VA  L  D  FA T   E         N +V+F  KK  +   D ++  +    +H +  +++EN
Sbjct:    2 LKEEGSEMRLAKVDAIEEKELAEEFNVDSFPTVKLFMNGDRKEPIEYTGKRTPSGIVQWLKRRSGPGAADLNSADSAAEFINTHNVSVVGFFDNLESEAAAVFKEVAFDLT-DVEFAVTASPEVFKEYEVTANKVVLF--KKFDDGRADFELSEEDKLDKHNLTNFIKEN 168

[Close]

BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000041085.1 (SMESG000041085.1)

HSP 1 Score: 536.184 bits (1380), Expect = 0.000e+0
Identity = 258/260 (99.23%), Postives = 260/260 (100.00%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKM+ADFSMENLEKFINDFL+EKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL
Sbjct:  231 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMMADFSMENLEKFINDFLEEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 490

HSP 2 Score: 410.994 bits (1055), Expect = 7.783e-136
Identity = 196/198 (98.99%), Postives = 198/198 (100.00%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQ+RTWVEEN+
Sbjct:   33 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQMRTWVEENI 230

HSP 3 Score: 71.633 bits (174), Expect = 9.766e-13
Identity = 40/91 (43.96%), Postives = 55/91 (60.44%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EFYAPWCGHCK LAP+YE  A  L  +   I IAK+D TA       + VSG+PT+    KN + +   YS  R  D ++KY+ S++ 
Sbjct:   37 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFA-FDYSGERSADGIIKYMVSKSG 125

HSP 4 Score: 70.8626 bits (172), Expect = 1.486e-12
Identity = 40/91 (43.96%), Postives = 55/91 (60.44%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFA-FDYSGERSADGIIKYMVSKSG 281
            +L+EFYAPWCGHCK LAP+YE  A  L  +   I IAK+D TA       + VSG+PT+    KN + +   YS  R  D ++KY+ S++ 
Sbjct:  385 VLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 473

[Close]

BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000041085.1 (SMESG000041085.1)

HSP 1 Score: 535.798 bits (1379), Expect = 0.000e+0
Identity = 258/260 (99.23%), Postives = 260/260 (100.00%), Query Frame = 1

Query: 1414 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 2193
            MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKM+ADFSMENLEKFINDFL+EKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL
Sbjct:  217 MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMMADFSMENLEKFINDFLEEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFDRQGRDRKSDL 476

HSP 2 Score: 410.994 bits (1055), Expect = 4.831e-136
Identity = 196/198 (98.99%), Postives = 198/198 (100.00%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM 596
            EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQ+RTWVEEN+
Sbjct:   19 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQMRTWVEENI 216

HSP 3 Score: 71.633 bits (174), Expect = 9.691e-13
Identity = 40/91 (43.96%), Postives = 55/91 (60.44%), Query Frame = 1

Query: 1876 VLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 2142
            +L+EFYAPWCGHCK LAP+YE  A  L  +   I IAK+D TA       + VSG+PT+    KN + +   YS  R  D ++KY+ S++ 
Sbjct:   23 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFA-FDYSGERSADGIIKYMVSKSG 111

HSP 4 Score: 70.8626 bits (172), Expect = 1.555e-12
Identity = 40/91 (43.96%), Postives = 55/91 (60.44%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFA-FDYSGERSADGIIKYMVSKSG 281
            +L+EFYAPWCGHCK LAP+YE  A  L  +   I IAK+D TA       + VSG+PT+    KN + +   YS  R  D ++KY+ S++ 
Sbjct:  371 VLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEAS 459

[Close]

BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000023147.1 (SMESG000023147.1)

HSP 1 Score: 142.124 bits (357), Expect = 1.238e-35
Identity = 84/197 (42.64%), Postives = 116/197 (58.88%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHT-----FDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEE 590
            +LVEFYAPWCGHCK LAPEY  AA  LK+++  I +AKVD T E     K  + GYPTLK FK+G+   DY G R+AD II ++  K+GP +  LK+ E       S D VVVGFF  ++S   KAF SVA+   +D  F  T     FDE    K++  ++IV+F       KF++ +  + G   +  IRT++++
Sbjct:   44 VLVEFYAPWCGHCKALAPEYASAAEKLKEKNSIIKLAKVDATVENDLASKFKIQGYPTLKFFKDGK-VMDYGGGRTADTIISWLEKKTGPPAATLKSVEEAKALIESKDVVVVGFFKDQASAAAKAFESVADS-KDDVVFGVTSQKAVFDE---FKVSSDDSIVLFK------KFDEGRNDFTGPFVDKDIRTFIDK 229

HSP 2 Score: 124.405 bits (311), Expect = 1.059e-29
Identity = 77/197 (39.09%), Postives = 112/197 (56.85%), Query Frame = 1

Query: 1552 AKKFIDSGKSIHFAISNVQEMNQELSEY-GIESPDFSKVYITARDERNQKFK-MIADFSMENLEKFINDFLQEKVPVYLKSESIPEKNDE-PVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIAS 2133
            AKKF+  G+ +   I+  +E N  + E+ G+   D     +   ++   KFK   A  S ENL  F+   L  KV  ++ ++ IPE  D+ PVKV+V KNFD +  D +K V +EFYAPWCGHCK LAP +++L +     +DIVIAKMD+TAN+V     +  FPTI + PK+S      +   R ++   K+I S
Sbjct:  277 AKKFL--GQVLFVIINTDEEDNDRVLEFFGMAKTDTPSFRMIQLEDDMVKFKPDDATISSENLNLFVQSVLDGKVKPHMMTQEIPEDWDKNPVKVLVGKNFDSVARDKSKAVFVEFYAPWCGHCKQLAPIWDQLGETYKDNTDIVIAKMDSTANEVEG-VRIQSFPTIKYFPKDSDEMV-DFEGDRTLETFKKFIDS 469

HSP 3 Score: 89.3521 bits (220), Expect = 2.532e-18
Identity = 47/115 (40.87%), Postives = 74/115 (64.35%), Query Frame = 1

Query: 1810 DEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIV-IAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSP 2148
            +E V V+   NF+E++ +  K VL+EFYAPWCGHCK+LAP+Y   A+KL  ++ I+ +AK+DAT  ND+ S +++ G+PT+ F  K+ K     Y  GR  D ++ ++  +   P
Sbjct:   23 EEGVLVLTNSNFNEVI-EKNKYVLVEFYAPWCGHCKALAPEYASAAEKLKEKNSIIKLAKVDATVENDLASKFKIQGYPTLKFF-KDGK--VMDYGGGRTADTIISWLEKKTGPP 133

HSP 4 Score: 63.929 bits (154), Expect = 2.954e-10
Identity = 34/87 (39.08%), Postives = 50/87 (57.47%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVF-KNGQFAFDYSGERSADGIIKYMVS 272
            + VEFYAPWCGHCK+LAP ++       K +  I IAK+D TA     E   +  +PT+K F K+     D+ G+R+ +   K++ S
Sbjct:  386 VFVEFYAPWCGHCKQLAPIWDQLGETY-KDNTDIVIAKMDSTA--NEVEGVRIQSFPTIKYFPKDSDEMVDFEGDRTLETFKKFIDS 469

[Close]

BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000010656.1 (SMESG000010656.1)

HSP 1 Score: 143.665 bits (361), Expect = 1.377e-35
Identity = 72/204 (35.29%), Postives = 118/204 (57.84%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNN-------IVIFHSKKMANKFEDTQVKYK---GDASEHQIRTWVEENM 596
            ILVEF+APWCGHCK LAPE+  AA  L   +PPI +A VD T ET   +++ VSGYP+LK+FKN  F  DYSG RS+DGI+ +M+     ++K + +  +F         +++G F+SE+  L+  F+     + EDF   ++F + +  +L Y  N       I++   + + N +E    K++    + +  ++ +++E+NM
Sbjct:  163 ILVEFFAPWCGHCKSLAPEFAKAAKILSNLNPPIQLATVDATVETDLAKEYHVSGYPSLKLFKNKNFFVDYSGPRSSDGIVDWMIKNRENAAKAVSSILDFRNVQNPQRVLLLGLFSSENDLLFTTFIDATNLVREDFSSIYSFSDEI--RLLYDANVDDGIGSIILLRPEYLRNIYEPDFTKFQHLNSNVTPFEVMSFIEKNM 364

HSP 2 Score: 122.479 bits (306), Expect = 9.995e-29
Identity = 76/209 (36.36%), Postives = 112/209 (53.59%), Query Frame = 3

Query:    6 HSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELK------TEENFNKFTASADPVVVGFFT-------SESSDLYKAFLSVAEKLNEDFRFAHTFDETLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEEN 593
            +++++VEFYAPWCGHCK+L P Y  AA  LKK +PPI + KVD T E++   + G+SGYPTLK FK+G   +DY   RS   I+ +M     P  +  K      T+ENF +   S+  ++V FF        S + +  KA   +   LN   + A T D T+ T L  + ++  + S K+  K ++  V Y G  S   I  W+ +N
Sbjct:   45 NNIVMVEFYAPWCGHCKQLTPIYTKAAVQLKKNNPPILLGKVDATVESELATRFGISGYPTLKFFKSG-IPYDYDDSRSESAIVNFMKKVGSPDWQPPKNYVLTLTKENFTQIVESSGYILVEFFAPWCGHCKSLAPEFAKA-AKILSNLNPPIQLA-TVDATVETDLAKEYHVSGYPSLKLF-KNKNFFVDYSGPRSSDGIVDWMIKN 249

HSP 3 Score: 74.3294 bits (181), Expect = 2.021e-13
Identity = 63/225 (28.00%), Postives = 107/225 (47.56%), Query Frame = 1

Query: 1432 RTHSNVKYFAKRPLIVALYNVDYEKNPK-GTNYWRNRILKVAKKFIDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIA--DFSMENLEKFINDFLQEKVPVYLKSESIPEKN-DEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVP--SPYEVSGF-PTIYFAPKNSKHSPKS 2085
            RT   ++   K+ L +  + VD+  + K  T  W  +I K+A  + D    I FAI++ +  + +L E  ++     ++ +    E + K++M A  +F  E++ KF++  L  KV   LKS  IP+    E +  VV   + E++ND   + L+  Y   C  C+SL      L+   S +S +    MD + ND+P  S  E   F PT+ F   ++   P S
Sbjct:  374 RTKVYLEKLEKKFLCIFFFTVDFSIHHKTATKKWLEKITKIAVNYKDQ---IQFAIADDERQSDKLRELRLDDSG-EEINVGCIGENDMKYRMSAMDEFDSEHIRKFLDSILAGKVFPILKSAPIPKTPLSEGITTVVGDTYKELINDIPGESLLLLYRSPCKSCQSLRNILSSLSSTFSGKS-LKFFSMDLSQNDMPPISGLEYERFQPTVNFIMDSTDSDPNS 593

HSP 4 Score: 73.559 bits (179), Expect = 2.806e-13
Identity = 41/119 (34.45%), Postives = 67/119 (56.30%), Query Frame = 1

Query: 1810 DEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAES-DIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNF 2160
            D  V V+ ++NFDE +N     V++EFYAPWCGHCK L P Y + A +L   +  I++ K+DAT  +++ + + +SG+PT+ F      +      S   + + +K + S    P KN+
Sbjct:   27 DSNVYVLNSENFDEFIN-ANNIVMVEFYAPWCGHCKQLTPIYTKAAVQLKKNNPPILLGKVDATVESELATRFGISGYPTLKFFKSGIPYDYDDSRSESAIVNFMKKVGSPDWQPPKNY 144

HSP 5 Score: 69.3218 bits (168), Expect = 5.862e-12
Identity = 44/122 (36.07%), Postives = 71/122 (58.20%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLS-AESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYI------ASEASSPLKNF 2160
            V  +  +NF +IV + +  +L+EF+APWCGHCKSLAP++ + AK LS     I +A +DAT   D+   Y VSG+P++      +K+    YS  R  D ++ ++      A++A S + +F
Sbjct:  145 VLTLTKENFTQIV-ESSGYILVEFFAPWCGHCKSLAPEFAKAAKILSNLNPPIQLATVDATVETDLAKEYHVSGYPSLKLF--KNKNFFVDYSGPRSSDGIVDWMIKNRENAAKAVSSILDF 263

[Close]

BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Match: SMESG000069732.1 (SMESG000069732.1)

HSP 1 Score: 109.768 bits (273), Expect = 5.283e-25
Identity = 70/225 (31.11%), Postives = 116/225 (51.56%), Query Frame = 1

Query: 1552 AKKFIDSGKSIHFAI---SNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIADFSME----------------------------NLEKFINDFLQEKVPVYLKSESIPEK-NDEPVKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIA 2130
             K F +S + +HF +      +E ++EL E  I  P+ + V     D  N    +I  F+++                             +++F+ D    K+  +LKS++IPE  N EPVK++V KNF+E+  +  K V +EFYAPWC +CK L P +E LAK+L    D++IAK+D T ND+ + +E+  FPT+    K+S +    YS  R  + + ++++
Sbjct:  242 GKVFQNSHRFMHFMVFMDDKFEEAHKELEEAAINHPEITFVMTDVTD--NTTSSLIKHFNVDLSNLPHLVLSDAKHKRLFLPGFNEINGKRIDQFLMDVKNGKIGQFLKSQNIPENWNSEPVKILVGKNFEEVALNKQKTVFVEFYAPWCNYCKQLEPIWERLAKELLDVPDLIIAKLDKTENDIKN-FEIKSFPTLKLFLKDS-NEVVDYSGPRTRERLKEFLS 462

HSP 2 Score: 71.633 bits (174), Expect = 1.049e-12
Identity = 43/145 (29.66%), Postives = 70/145 (48.28%), Query Frame = 3

Query:    3 EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETKTCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFA 437
            +H  IL+ FYAPWC   +KL P +E AA  L + +  I + KVD T ET    K  +  YPT+ +FK  +    YS       I+ +++SK       + + ++ ++     D +    F   +  +   F+  AE L +D +FA
Sbjct:   41 DHKPILINFYAPWCKFSQKLLPHFENAAKNLLQMESRIKLGKVDVTVETDLANKFKIKSYPTIILFKEDR-QIPYSKAHHHLTILNWLISKVDKLIISVNSTDSLDEVRQKTDVL----FVINNDIMGDTFVGAAE-LIDDVQFA 179

HSP 3 Score: 64.3142 bits (155), Expect = 1.785e-10
Identity = 41/101 (40.59%), Postives = 57/101 (56.44%), Query Frame = 3

Query:   15 ILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTA-ETKTCEKHGVSGYPTLKVF-KNGQFAFDYSGERSADGIIKYMVSKSGPSSKELKTEE 311
            + VEFYAPWC +CK+L P +E  A  L    P + IAK+D T  + K  E   +  +PTLK+F K+     DYSG R+ +  +K  +SK    +  LK EE
Sbjct:  380 VFVEFYAPWCNYCKQLEPIWERLAKELLDV-PDLIIAKLDKTENDIKNFE---IKSFPTLKLFLKDSNEVVDYSGPRTRER-LKEFLSKFVNLNNALKNEE 475

HSP 4 Score: 58.9214 bits (141), Expect = 8.421e-9
Identity = 38/109 (34.86%), Postives = 58/109 (53.21%), Query Frame = 1

Query: 1819 VKVVVAKNFDEIVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKK-LSAESDIVIAKMDATA-NDVPSPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEA 2139
            V VV  + F+E++ND  K +LI FYAPWC   + L P +E  AK  L  ES I + K+D T   D+ + +++  +PTI    K  +  P  YS       +L ++ S+ 
Sbjct:   27 VFVVNNETFEELIND-HKPILINFYAPWCKFSQKLLPHFENAAKNLLQMESRIKLGKVDVTVETDLANKFKIKSYPTIILF-KEDRQIP--YSKAHHHLTILNWLISKV 131

The following BLAST results are available for this feature:

BLAST of Protein disulfide-isomerase vs. Ensembl Human
BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
BLAST of Protein disulfide-isomerase vs. Ensembl Fly
BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
BLAST of Protein disulfide-isomerase vs. TrEMBL
BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
BLAST of Protein disulfide-isomerase vs. Planmine SMEST

BLAST of Protein disulfide-isomerase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDIA3	5.893e-88	54.66	protein disulfide isomerase family A member 3 [Sou...	[more]
PDIA4	4.043e-54	44.58	protein disulfide isomerase family A member 4 [Sou...	[more]
PDIA4	4.099e-54	44.58	protein disulfide isomerase family A member 4 [Sou...	[more]
P4HB	4.618e-32	36.18	prolyl 4-hydroxylase subunit beta [Source:HGNC Sym...	[more]
P4HB	3.422e-31	36.32	prolyl 4-hydroxylase subunit beta [Source:HGNC Sym...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdi-3	1.835e-77	48.84	pep chromosome:WBcel235:I:7015912:7021743:-1 gene:...	[more]
pdi-3	1.835e-77	48.84	pep chromosome:WBcel235:I:7015912:7020790:-1 gene:...	[more]
pdi-3	1.835e-77	48.84	pep chromosome:WBcel235:I:7015912:7020797:-1 gene:...	[more]
C14B9.2	1.137e-45	40.61	Probable protein disulfide-isomerase A4 [Source:U...	[more]
pdi-2	3.165e-36	39.69	Protein disulfide-isomerase 2 [Source:UniProtKB/S...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ERp60	5.952e-92	57.09	gene:FBgn0033663 transcript:FBtr0088058	[more]
Pdi	1.729e-32	36.41	gene:FBgn0286818 transcript:FBtr0346644	[more]
Pdi	1.729e-32	36.41	gene:FBgn0286818 transcript:FBtr0075648	[more]
CG9302	6.037e-18	49.40	gene:FBgn0032514 transcript:FBtr0080470	[more]
prtp	2.908e-17	45.45	gene:FBgn0030329 transcript:FBtr0332954	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdia3	1.985e-88	54.03	protein disulfide isomerase family A, member 3 [So...	[more]
pdia7	5.200e-83	53.20	protein disulfide isomerase family A, member 7 [So...	[more]
pdia8	3.123e-72	48.40	protein disulfide isomerase family A, member 8 [So...	[more]
pdia8	3.123e-72	48.40	protein disulfide isomerase family A, member 8 [So...	[more]
pdia4	7.080e-53	44.76	protein disulfide isomerase family A, member 4 [So...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdia3	2.996e-89	55.06	protein disulfide isomerase family A member 3 [Sou...	[more]
pdia3	5.384e-83	55.22	protein disulfide isomerase family A member 3 [Sou...	[more]
pdia3	1.566e-82	55.22	protein disulfide isomerase family A member 3 [Sou...	[more]
pdia3	1.441e-73	49.39	protein disulfide isomerase family A member 3 [Sou...	[more]
pdia3	5.098e-72	54.55	protein disulfide isomerase family A member 3 [Sou...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pdia3	1.312e-86	53.85	protein disulfide isomerase associated 3 [Source:M...	[more]
Pdia4	4.947e-54	44.18	protein disulfide isomerase associated 4 [Source:M...	[more]
P4hb	3.258e-30	35.24	prolyl 4-hydroxylase, beta polypeptide [Source:MGI...	[more]
Pdia3	2.303e-29	64.20	protein disulfide isomerase associated 3 [Source:M...	[more]
Pdia2	4.960e-28	46.72	protein disulfide isomerase associated 2 [Source:M...	[more]

BLAST of Protein disulfide-isomerase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P38657\|PDIA3_BOVIN	7.268e-89	54.66	Protein disulfide-isomerase A3 OS=Bos taurus OX=99...	[more]
sp\|Q5RDG4\|PDIA3_PONAB	2.830e-87	54.66	Protein disulfide-isomerase A3 OS=Pongo abelii OX=...	[more]
sp\|P30101\|PDIA3_HUMAN	2.830e-87	54.66	Protein disulfide-isomerase A3 OS=Homo sapiens OX=...	[more]
sp\|Q4VIT4\|PDIA3_CHLAE	4.042e-87	54.66	Protein disulfide-isomerase A3 OS=Chlorocebus aeth...	[more]
sp\|Q8JG64\|PDIA3_CHICK	8.706e-86	54.88	Protein disulfide-isomerase A3 OS=Gallus gallus OX...	[more]

BLAST of Protein disulfide-isomerase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8IGN6	2.373e-109	61.39	Protein disulfide-isomerase OS=Macrostomum lignano...	[more]
A0A1I8IJ81	2.844e-109	61.39	Protein disulfide-isomerase OS=Macrostomum lignano...	[more]
T1G058	1.813e-107	64.73	Protein disulfide-isomerase OS=Helobdella robusta ...	[more]
K1Q7T5	5.587e-107	65.22	Protein disulfide-isomerase OS=Crassostrea gigas O...	[more]
R7UDG3	1.313e-106	64.48	Protein disulfide-isomerase OS=Capitella teleta OX...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdia3	6.804e-88	54.03	protein disulfide isomerase family A member 3 [Sou...	[more]
pdia7	3.370e-78	51.81	protein disulfide-isomerase A3-like [Source:NCBI g...	[more]
pdia8	1.885e-77	50.40	protein disulfide-isomerase A3-like [Source:NCBI g...	[more]
pdia8	2.274e-65	46.80	protein disulfide-isomerase A3-like [Source:NCBI g...	[more]
pdia8	1.646e-61	45.20	protein disulfide-isomerase A3-like [Source:NCBI g...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdia3	5.542e-84	53.47	protein disulfide isomerase family A, member 3 [So...	[more]
pdia4	5.950e-50	40.40	protein disulfide isomerase family A, member 4 [So...	[more]
p4hb	6.922e-32	35.45	prolyl 4-hydroxylase, beta polypeptide [Source:ZFI...	[more]
ENSPMAT00000002052.1	9.622e-26	44.62	pep scaffold:Pmarinus_7.0:GL480798:2613:20969:-1 g...	[more]
TMX3	8.506e-24	30.93	thioredoxin related transmembrane protein 3 [Sourc...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
PDI1	6.278e-30	37.88	Protein disulfide isomerase; multifunctional oxido...	[more]
EUG1	3.685e-21	35.53	Protein disulfide isomerase of the endoplasmic ret...	[more]
MPD1	6.155e-13	29.41	Member of the protein disulfide isomerase (PDI) fa...	[more]
TRX1	6.887e-9	37.14	Cytoplasmic thioredoxin isoenzyme; part of thiored...	[more]
TRX2	1.662e-8	33.70	Cytoplasmic thioredoxin isoenzyme; part of thiored...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO31634	2.654e-73	50.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32930	4.265e-60	42.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33843	1.028e-45	58.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36830	2.623e-36	42.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47340	2.771e-26	51.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein disulfide-isomerase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdia3	3.185e-90	55.65	protein disulfide isomerase family A member 3 [Sou...	[more]
pdia8	1.566e-62	44.18	protein disulfide-isomerase A3 [Source:NCBI gene;A...	[more]
pdia8	4.249e-62	44.18	protein disulfide-isomerase A3 [Source:NCBI gene;A...	[more]
pdia4	1.178e-52	44.98	protein disulfide isomerase family A member 4 [Sou...	[more]
pdia2	7.788e-36	38.31	protein disulfide-isomerase [Source:NCBI gene;Acc:...	[more]

BLAST of Protein disulfide-isomerase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000041085.1	7.783e-136	99.23	SMESG000041085.1	[more]
SMESG000041085.1	4.831e-136	99.23	SMESG000041085.1	[more]
SMESG000023147.1	1.238e-35	42.64	SMESG000023147.1	[more]
SMESG000010656.1	1.377e-35	35.29	SMESG000010656.1	[more]
SMESG000069732.1	5.283e-25	31.11	SMESG000069732.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30012219 ID=SMED30012219|Name=Protein disulfide-isomerase|organism=Schmidtea mediterranea sexual|type=transcript|length=2291bp
AAGAACATTCTGTTATTCTTGTTGAATTTTATGCTCCATGGTGTGGACAC
TGTAAGAAATTAGCTCCTGAATATGAAATCGCAGCCACAGCTTTAAAGAA
ACAAGATCCACCCATCGCAATTGCTAAAGTAGATTGTACTGCTGAAACTA
AAACCTGTGAAAAGCATGGTGTTAGTGGATATCCAACCCTTAAAGTTTTT
AAAAATGGGCAATTCGCATTTGATTATAGCGGAGAACGATCAGCCGATGG
AATAATTAAATATATGGTATCGAAAAGTGGCCCTTCATCTAAAGAACTTA
AAACTGAAGAAAATTTTAATAAATTTACTGCTTCAGCAGACCCGGTTGTT
GTTGGGTTTTTCACATCAGAATCTTCAGATCTGTATAAGGCATTTTTAAG
TGTGGCCGAAAAATTAAATGAAGACTTTCGATTTGCCCACACTTTTGATG
AGACTTTAAGTACAAAGTTGAATTATAAAAATAATATTGTTATTTTCCAT
TCCAAAAAAATGGCAAATAAATTTGAAGATACCCAAGTGAAGTACAAAGG
AGACGCATCAGAACATCAAATAAGAACCTGGGTTGAAGAAAATATGTAAG
TTAATTATGTTCAGATTCGATTTTAAAATTAACTGATAAATTTTAATTTT
AAACCTTAAACGCTTATTGGTCGCCACGTTTTAACCAATAAGGGACATCA
TAAGTGGACTATAAGCTCGATTAGTATGATAGACGTGTCAATTTTCTATT
TGAAAATTCGATAATTGTATTAAGAATTATGTCGTAATTGTTTTTATGCA
ATTATTATTCACTGGAATTGCAATTTATCTCTAATCTGAATCTGTTGAAA
TTAAAAAAAACTTTGTATTGAAATCGTTTCATATTTAAATTTATTATTTA
TAAATGTCTTTCAAGTGTGCAGCGTTTTAAGTAACCGATGACGTAACTGC
TGTCATTGTGATTTATTTAATTGTATAATTCAATTTTACAGCTTGTTATA
TTAATCAAAATTAACTTCGCACAGGGTGATTTATATTGGGTAATTTTTTA
ATTGGTTTTGATTTACTTGAAAATATAATAAAATCCAATTAAATTAATGA
TTTCGATGTTTAATCTGAAAAAAAATAATATTCGGGTAGATTAGTGTTAT
AAAGTGAGCACATAAAATGGACTTTCCTTTTAGATCGATGAGGATATTTT
TAATTTGGCCTTTGTAAATTGATTCCATATGTAATGCTTTATATAAGATA
AACTATGCGGTTAACTGTATCAAATTTATTTAGCTATGTTTCCTTTATCA
TAAATGGTTTATCGAATTTTAAAGAGATATATTTTATAGCGAATACTAAA
AATCGGCGGATTATTTAGGAATTTTTAATTTCCAATTACGAAATTGATAA
TTGTATTCTTAGCATGGGATTGGCTGGCCATAGAACTCATTCTAATGTCA
AATACTTTGCCAAAAGACCTTTGATCGTCGCTCTTTACAATGTTGACTAC
GAAAAGAATCCTAAAGGAACAAACTACTGGAGAAATAGAATATTGAAAGT
TGCCAAAAAATTTATCGATTCTGGAAAATCTATACATTTTGCTATTTCCA
ATGTTCAAGAAATGAACCAAGAACTGTCAGAATATGGCATCGAATCTCCA
GATTTCAGTAAAGTATACATCACAGCCAGAGATGAAAGAAATCAGAAATT
TAAAATGATAGCAGATTTTTCTATGGAAAATTTGGAAAAATTCATTAACG
ATTTCCTACAAGAGAAAGTCCCAGTCTATTTGAAATCTGAATCTATTCCA
GAGAAAAACGATGAACCGGTTAAAGTTGTTGTGGCTAAGAATTTCGACGA
GATCGTTAACGATCCTACAAAAGATGTATTGATTGAGTTCTATGCCCCGT
GGTGCGGACATTGCAAGAGTTTGGCGCCGAAATATGAGGAATTAGCCAAG
AAACTGTCCGCTGAATCAGATATTGTTATTGCAAAAATGGATGCTACTGC
AAACGATGTTCCGAGTCCTTATGAGGTGTCAGGATTCCCGACAATTTATT
TTGCGCCGAAGAATTCTAAACACTCTCCTAAATCATACAGTAGCGGTCGA
GAGGTCGACGATATGTTGAAGTATATTGCATCTGAAGCATCTTCTCCATT
GAAAAATTTCGATCGACAAGGCAGAGATCGTAAATCAGATCTTTAGAAAT
TCTAGTTTATTGAAATTAAATCATCATTGACAGGCGTTGTATTTTGCTAT
TCAATTTATCTGGTTTATTAACGTGTATGTAATTGTGTACT

protein sequence of SMED30012219-orf-1

>SMED30012219-orf-1 ID=SMED30012219-orf-1|Name=SMED30012219-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=261bp
MGLAGHRTHSNVKYFAKRPLIVALYNVDYEKNPKGTNYWRNRILKVAKKF
IDSGKSIHFAISNVQEMNQELSEYGIESPDFSKVYITARDERNQKFKMIA
DFSMENLEKFINDFLQEKVPVYLKSESIPEKNDEPVKVVVAKNFDEIVND
PTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSAESDIVIAKMDATANDVP
SPYEVSGFPTIYFAPKNSKHSPKSYSSGREVDDMLKYIASEASSPLKNFD
RQGRDRKSDL*

protein sequence of SMED30012219-orf-2

>SMED30012219-orf-2 ID=SMED30012219-orf-2|Name=SMED30012219-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=199bp
EHSVILVEFYAPWCGHCKKLAPEYEIAATALKKQDPPIAIAKVDCTAETK
TCEKHGVSGYPTLKVFKNGQFAFDYSGERSADGIIKYMVSKSGPSSKELK
TEENFNKFTASADPVVVGFFTSESSDLYKAFLSVAEKLNEDFRFAHTFDE
TLSTKLNYKNNIVIFHSKKMANKFEDTQVKYKGDASEHQIRTWVEENM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000499	cell
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0000484	secretory system
PLANA:0003116	parenchymal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036249	Thioredoxin-like_sf
IPR005788	Disulphide_isomerase
IPR013766	Thioredoxin_domain
IPR012336	Thioredoxin-like_fold
IPR017937	Thioredoxin_CS

Vocabulary: **biological process**
Term	Definition
GO:0045454	cell redox homeostasis

Vocabulary: **molecular function**
Term	Definition
GO:0003756	protein disulfide isomerase activity
GO:0016853	isomerase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005783	endoplasmic reticulum

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00421	THIOREDOXIN	coord: 204..215 score: 35.14 coord: 155..163 score: 58.58 coord: 163..172 score: 65.89
None	No IPR available	PFAM	PF13848	Thioredoxin_6	coord: 5..113 e-value: 2.1E-12 score: 47.3
None	No IPR available	PANTHER	PTHR18929:SF60	PROTEIN DISULFIDE-ISOMERASE	coord: 1..246
None	No IPR available	PANTHER	PTHR18929	PROTEIN DISULFIDE ISOMERASE	coord: 1..246
None	No IPR available	CDD	cd02995	PDI_a_PDI_a'_C	coord: 135..238 e-value: 7.02531E-60 score: 182.756
None	No IPR available	CDD	cd03073	PDI_b'_ERp72_ERp57	coord: 4..115 e-value: 6.27853E-39 score: 129.764
IPR013766	Thioredoxin domain	PFAM	PF00085	Thioredoxin	coord: 136..239 e-value: 3.1E-30 score: 104.2
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 117..243 score: 14.686
IPR036249	Thioredoxin-like superfamily	GENE3D	G3DSA:3.40.30.10		coord: 123..257 e-value: 1.3E-41 score: 143.7
IPR036249	Thioredoxin-like superfamily	GENE3D	G3DSA:3.40.30.10		coord: 8..117 e-value: 7.0E-35 score: 121.4
IPR036249	Thioredoxin-like superfamily	SUPERFAMILY	SSF52833	Thioredoxin-like	coord: 6..133
IPR036249	Thioredoxin-like superfamily	SUPERFAMILY	SSF52833	Thioredoxin-like	coord: 134..239
IPR005788	Disulphide isomerase	TIGRFAM	TIGR01126	TIGR01126	coord: 139..241 e-value: 2.6E-36 score: 122.1
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 156..174