NPHS1-7

Query: 1050 TIMILVHYPPEKIELNEEPVDNQLESQSK-QFTCSS-KGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIR----KYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVI---QLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKH-QTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKL 2303
            ++++ V YP +K+ +   P   +L + ++ +  C +  GN EP   + W       R V  S   ++ +  ++ + G++    ST    L+       N  K  C         L+   Q+ V F P +++++ +     P   ++NLTC + SSNP  N+ W +   G+R E + +   +    + + G A   S+ +  ++R DHG    C    A +   +S  Y LNVLY P     Q+  +  +      + +       NP   +   F W F      Y       P   I           S    H++N+T A   D G Y   C+N+ G     + L+V+++P ++  Q  + V V    +IV  V  +           I P      RL E D + Q++++M+K I   P  R ++
Sbjct:  432 SLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEP--SLMWY---KDSRTVTES---RLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKA-----GQLSASTQLAVQFPPTNVTILANASALRPGD-ALNLTCVSVSSNPPVNLSWDKE--GERLEGVAAPPRR----APFKGSAAARSVLLQVSSR-DHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAVEQGEALLPVSVSA---NP---APEAFNWTF----RGYRLSPAGGPRHRI----------LSSGALHLWNVTRA---DDGLYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANP----------ILPGMFNWERLGE-DEEDQSLDDMEK-ISRGPTGRLRI 803          

Query: 1050 TIMILVHYPPEKIELNEEPVDNQLESQSK-QFTCSS-KGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIR----KYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVI---QLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKH-QTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKL 2303
            ++++ V YP +K+ +   P   +L + ++ +  C +  GN EP   + W       R V  S   ++ +  ++ + G++    ST    L+       N  K  C         L+   Q+ V F P +++++ +     P   ++NLTC + SSNP  N+ W +   G+R E + +   +    + + G A   S+ +  ++R DHG    C    A +   +S  Y LNVLY P     Q+  +  +  E     L    S  NP   +   F W F          Y   P    R        + S    H++N+T A   D G Y   C+N+ G     + L+V+++P ++  Q  + V V    +IV  V  +           I P      RL E D + Q++++M+K I   P  R ++
Sbjct:  432 SLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEP--SLMWY---KDSRTVTES---RLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKA-----GQLSASTQLAVQFPPTNVTILANASALRP-GDALNLTCVSVSSNPPVNLSWDKE--GERLEGVAAPPRR----APFKGSAAARSVLLQVSSR-DHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAV--EQGEALLPVSVS-ANP---APEAFNWTF--------RGYRLSPAGGPRHR------ILSSGALHLWNVTRA---DDGLYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANP----------ILPGMFNWERLGE-DEEDQSLDDMEK-ISRGPTGRLRI 803          

Query: 1392 IKVVFAPNHISLIPDP-QGGIPETRSVNLTC-FTGSSNPSSNIQWFRTEPGKRPED---ITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQP---NTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEV 2381
            I +V  P H++L P   + GI  T  V L+C  TGS  P   I+W+R      P++   I   SN+ ++ +               + ++ H   Y+C  +     ++      L    P ++  FS  K+ N G    L C   G  P             P +T   +  +D+P   +   R N Y + D  +  H    N+T    +D G Y C   N  G       +NV   P ++   +  +   +G + ++  +   YP  + IKW+          L  PD+  Q + E         N   KLT V              D G+Y C V
Sbjct:   98 ILMVIDPLHVTLTPKKLKTGIGST--VILSCALTGS--PEFTIRWYRNTELVLPDEAISIRGLSNETLLIT---------------SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFS-EKVVNPGEQFSLMCAAKGAPP-------------PTVT---WALDDEPIVRDGSHRTNQYTMSDGTTISH---MNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRN--ITAVAGRDTLINCRVIGYP-YYSIKWY-------KDALLLPDNHRQVVFE---------NGTLKLTDVQK----------GMDEGEYLCSV 367          

Query:  753 SEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGR-LVAHSETFKILERVKKANPGA 1277
            S  S A  +  N+ Y P  + +    PL +   G+ +S QC   + +P+ V   ++K  G+   K+   N      ++   + C +    G++    S    + V Y P ++ ++  P D  +E +S   TC S  N  P+S   W  FD   + L  HS+  + LE VK  + GA
Sbjct:  312 SWCSWASPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKN-GRLLGKESQLNFDSISPEDAGSYSCWVNNSIGQT---ASKAWTLEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANP-PVSHYTW--FDWNNQSLPYHSQKLR-LEPVKVQHSGA 479          

Query:  753 SEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGR-LVAHSETFKILERVKKANPGA 1277
            S  S A  +  N+ Y P  + +    PL +   G+ +S QC   + +P+ V   ++K  G+   K+   N      ++   + C +    G++    S    + V Y P ++ ++  P D  +E +S   TC S  N  P+S   W  FD   + L  HS+  + LE VK  + GA
Sbjct:  312 SWCSWASPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFWEKN-GRLLGKESQLNFDSISPEDAGSYSCWVNNSIGQT---ASKAWTLEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANP-PVSHYTW--FDWNNQSLPYHSQKLR-LEPVKVQHSGA 479          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGG--IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMM--PSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFS-LPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFS--FHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYP-KIHEIKWF 2189
             E      TC ++G + PL+++ W    +   LV   +  K  +     N  A  +  ST+ + + R  N  ++KC      L+  L + + + V + P  + + P   G   +   +S  L C T SSNP+++I W   +  +  +D   H     +   +  +G  + + L+   T   D GT+  CI +H      ++  + LNV+YPP + +   +  + +EG+  + +  T  GNP+I   S +QW                     R+N           F    + +       D G Y+    N+ G T   + L V +S  +    S+ V   +G  ++L+ +    P K + I W+
Sbjct:  445 FEGDIVNVTCEAQGGN-PLAELSW-YRGSEKHLVKGRKKMKWSQVNGAHNEVAGFSSYSTLALRVDRTMNTQRLKCEATNAALDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKSARLVCGTLSSNPAAHISW---QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD-GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFK-ENLTVRGNPAI---SLWQW---------------------RKNGVPFDHTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAVEYSARIT-SISTPVIAATGDTVLLECEADGEPSKANMIHWY 778          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTL-------FDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHI---SLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGK-RPEDI----TSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYP---PVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENA--GGVTVEFMFLNVYFSPI---------LKHQTSSRVYVKS-GSNIVLQVKW 2153
            +  +S  F CS++ + EP+   +W         +   G L  H   F  +++         N  E  +K+T +   +  + +C +++     +  +  + ++  P  +   +  P+    + E   +N+TC   +  P   + W+    GK    D+    T H NK           +++SL +  ++R DHG +  C       +  I+    L+VL+P   P +++   P     G+ V + C  +GGNP             P +  Y      Q ++ +     ++ +++SF         A+   +   Y C+  N+  G    + M L V + P          +++ +S+ +  KS  SN   Q+ W
Sbjct:   31 IAGESITFRCSAEKSPEPIVYSQWKSNTGSLLGYHQEGILPGHQGRFSYIKQ---------NAEELHLKITHVNLDDDGEYECQMLHPEEGPIRAKSFLNIIVPPQLVYFSNYQPNSIIAVKENTPLNITCVVPNVKPEPEVLWYMD--GKVMSRDVKQASTPHLNKTF--------TVYTSLVVQ-SDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEILRNPSALRSGDNVTIACSVTGGNPP------------PDVFWYHENKRLQSHSTLDTRSKEIKNIYSF--------IASQNDNMAEYECRANNSRTGNPKRKAMKLEVNYPPASVELFGESNIRYGSSANIQCKSLPSNPASQITW 365          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGG--IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMM--PSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFS-LPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFS--FHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYP-KIHEIKWF 2189
             E      TC ++G + PL+++ W    +   LV   +  K  +     N  A  +  ST+ + + R  N  ++KC      L+  L + + + V + P  + + P   G   +   +S  L C T SSNP+++I W   +  +  +D   H     +   +  +G  + + L+   T   D GT+  CI +H      ++  + LNV+YPP + +   +  + +EG+  + +  T  GNP+I   S +QW                     R+N           F    + +       D G Y+    N+ G T   + L V +S  +    S+ V   +G  ++L+ +    P K + I W+
Sbjct:  143 FEGDIVNVTCEAQGGN-PLAELSW-YRGSEKHLVKGRKKMKWSQVNGAHNEVAGFSSYSTLALRVDRTMNTQRLKCEATNAALDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKSARLVCGTLSSNPAAHISW---QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD-GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFK-ENLTVRGNPAI---SLWQW---------------------RKNGVPFDHTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAVEYSARIT-SISTPVIAATGDTVLLECEADGEPSKANMIHWY 476          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKA-NPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGG--IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMM--PSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFS-LPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFS--FHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYP-KIHEIKWF 2189
             E      TC ++G + PL+++ W               ++  E+V  A N  A  +  ST+ + + R  N  ++KC      L+  L + + + V + P  + + P   G   +   +S  L C T SSNP+++I W   +  +  +D   H     +   +  +G  + + L+   T   D GT+  CI +H      ++  + LNV+YPP + +   +  + +EG+  + +  T  GNP+I   S +QW                     R+N           F    + +       D G Y+    N+ G T   + L V +S  +    S+ V   +G  ++L+ +    P K + I W+
Sbjct:  445 FEGDIVNVTCEAQGGN-PLAELSW---------------YRGSEKVNGAHNEVAGFSSYSTLALRVDRTMNTQRLKCEATNAALDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKSARLVCGTLSSNPAAHISW---QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD-GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFK-ENLTVRGNPAI---SLWQW---------------------RKNGVPFDHTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAVEYSARIT-SISTPVIAATGDTVLLECEADGEPSKANMIHWY 765          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTL-------FDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHI---SLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGK-RPEDI----TSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYP---PVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENA--GGVTVEFMFLNVYFSPI---------LKHQTSSRVYVKS-GSNIVLQVKW 2153
            +  +S  F CS++ + EP+   +W         +   G L  H   F  +++         N  E  +K+T +   +  + +C +++     +  +  + ++  P  +   +  P+    + E   +N+TC   +  P   + W+    GK    D+    T H NK           +++SL +  ++R DHG +  C       +  I+    L+VL+P   P +++   P     G+ V + C  +GGNP             P +  Y      Q ++ +     ++ +++SF         A+   +   Y C+  N+  G    + M L V + P          +++ +S+ +  KS  SN   Q+ W
Sbjct:   31 IAGESITFRCSAEKSPEPIVYSQWKSNTGSLLGYHQEGILPGHQGRFSYIKQ---------NAEELHLKITHVNLDDDGEYECQMLHPEEGPIRAKSFLNIIVPPQLVYFSNYQPNSIIAVKENTPLNITCVVPNVKPEPEVLWYMD--GKVMSRDVKQASTPHLNKTF--------TVYTSLVVQ-SDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEILRNPSALRSGDNVTIACSVTGGNPP------------PDVFWYHENKRLQSHSTLDTRSKEIKNIYSF--------IASQNDNMAEYECRANNSRTGNPKRKAMKLEVNYPPASVELFGESNIRYGSSANIQCKSLPSNPASQITW 365          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKA-NPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGG--IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMM--PSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFS-LPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFS--FHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYP-KIHEIKWF 2189
             E      TC ++G + PL+++ W               ++  E+V  A N  A  +  ST+ + + R  N  ++KC      L+  L + + + V + P  + + P   G   +   +S  L C T SSNP+++I W   +  +  +D   H     +   +  +G  + + L+   T   D GT+  CI +H      ++  + LNV+YPP + +   +  + +EG+  + +  T  GNP+I   S +QW                     R+N           F    + +       D G Y+    N+ G T   + L V +S  +    S+ V   +G  ++L+ +    P K + I W+
Sbjct:  143 FEGDIVNVTCEAQGGN-PLAELSW---------------YRGSEKVNGAHNEVAGFSSYSTLALRVDRTMNTQRLKCEATNAALDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKSARLVCGTLSSNPAAHISW---QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD-GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFK-ENLTVRGNPAI---SLWQW---------------------RKNGVPFDHTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAVEYSARIT-SISTPVIAATGDTVLLECEADGEPSKANMIHWY 463          

Query: 1293 STVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGG--IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMM--PSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFS-LPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFS--FHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYP-KIHEIKWF 2189
            ST+ + + R  N  ++KC      L+  L + + + V + P  + + P   G   +   +S  L C T SSNP+++I W   +  +  +D   H     +   +  +G  + + L+   T   D GT+  CI +H      ++  + LNV+YPP + +   +  + +EG+  + +  T  GNP+I   S +QW                     R+N           F    + +       D G Y+    N+ G T   + L V +S  +    S+ V   +G  ++L+ +    P K + I W+
Sbjct:   20 STLALRVDRTMNTQRLKCEATNAALDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKSARLVCGTLSSNPAAHISW---QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD-GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFK-ENLTVRGNPAI---SLWQW---------------------RKNGVPFDHTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAVEYSARIT-SISTPVIAATGDTVLLECEADGEPSKANMIHWY 297          

Query:  777 LETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNP----------RPVV-SLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTI---MILVHYPPEKIELNEEPVDNQLESQS-KQFTCSSKGNSEPLSQIEW----TLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQD-HGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIE 2411
            L   + Y P  + L+ +N   Q ++G  +   C +   NP          RP+  S YK           S+N+ LT       F  +   ++ +   LT N +    + V YPP    L      + L S S  +  CSS G + P + ++W     + +A  +LV    T ++   V  ++  A+                    KC +    +++ L   K + V F P  + +   P+  +P  R+  L C + SSNP + I W++      P +  + +N+   P  + G    S+L ++    QD  G +Y C   +  +   + +   L++LYPP  +       P    FV ++     G P  +   +      P++ +Y +  +  P   I  N      + S       NI+  +  D G Y C+  N+ G  +  + + V ++P +   +  R +V +G   VL                      I AR  E  H    +   +   DL+  +R   +  N T  L I+S+   D G++ C V N RG  + +
Sbjct:  338 LNLTVLYAPKDVYLSGAN---QAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFIAVCHALNTE---LTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPT-LQWYKNDKIINAPSKLVDSKITSELSLLVNASDNNAI-------------------YKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRA-KLICDSSSSNPPAKISWWKD---GIPVEGLNLANR---PGLWGGSV--STLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFE------TPQSTTFVGVE-----GAPFHV---ELLASGNPMVITYTWTKDGLP---ISSNSLSGQRLISDGPR--LNISRLSRNDAGVYICEALNSQGTALLEIQVAVEYAPTITAVSEGRSFV-AGEPAVLAC-------------------HIQARPLEAAH----VRWSRDGYDLA--TRTISSFENGTALLQIASVERSDIGNFTCIVDNQRGAPAAQ 823          

Query:  852 GSLISFQCSSDNGNPRPVVSLYKKRFG-KKPQK---QVSANV---ILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLE-SQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGGIPETRSV-NLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPP-VIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHI---FNITAAAPKDRGWYSCQCENA--GGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            G  +   C S  GNP   ++ Y+       PQ+   ++S NV        DN A   C  + +   +P      + +L  Y P+ + L+     NQ +   S Q +C +   S P ++I W++    GR + +S T+K       ++ G +++  S + +T+  +   F   C  +   L   +     + V++ P+   L     G I  + S+  L C +   NP   +QW++ +     + I +       PS      I S L++   N  D+  IYKC V +A ++  +     L V +PP  +++  +PK    G   +L C +S  NP     ++  W            ++D    E   N    P ++      +    NIT     D   Y+CQ  N        E + L++ + P  +   S+      G+   +++  S  P +    W                         K  + +S NS     +++   +LNIS ++  D G Y CE  NS+G + +E Q+
Sbjct:  266 GQEVQIACRSRGGNPPAQLTWYRNGVAISSPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVL--YAPKDVYLSGA---NQAKVGDSVQLSCVT-APSNPQARISWSI---NGRPLDNS-TYKT---TSSSDGGWVSS--SNISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKND-----KIINA-------PSKLVDSKITSELSLL-VNASDNNAIYKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRAKLICDSSSSNPP----AKISW------------WKDGIPVE-GLNLANRPGLWGGSVSTLEMYVNITQDL--DGIVYTCQSHNEVLQRSVHETISLDILYPPKFETPQSTTFVGVEGAPFHVELLASGNPMVITYTW------------------------TKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAGVYICEALNSQGTALLEIQV 733          

Query:  786 NIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSANV------ILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMP---SNYSG---IAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISK--EYFLNVLYPPVIQLFSLPKIPNEG-NFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHH-HIFNITAAAPKDRGWYSCQCENA-GGVTVEFMFLNVYFSPILKHQTS-SRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQ 2417
            N+ Y PS  +LT  N       GS++  QCSS  GNP P +  YK  +    P K V + +      ++   DN A + C ++  +   P   + T+   VH+PPE ++++  P  N +     +  C S  +S P ++I W       +     E   +  R      G+++TLE  V +T  +  +G    C    Q  N + Q    + +     + ++  P+   P++     T F G      +++   +     P  IT    KD +P   ++ SG   I+    LNI   +R D G +Y C      +NS+ +   E  + V Y P I   S      EG +FV        G P++++    Q +  P+  ++     D  +   R        + SF +   +  I +    D G ++C  +N  G    + + L V  +P + H    +R   + G    L  +  + P+   I W          R +  D + Q  N+ K       +   ++  +N    L I + +  DYG Y C V NS GQ+S   +
Sbjct:  441 NVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKNDKIINAPSKLVDSKITSELSLLVNASDNNAIYKCKVQNAAIDIPLFATKTLG--VHFPPETVKISVVP-KNLVPGIRAKLICDSS-SSNPPAKISW------WKDGIPVEGLNLANRPGLWG-GSVSTLEMYVNIT--QDLDGIVYTC----QSHNEVLQRSVHETI----SLDILYPPKFETPQS-----TTFVGVEGAPFHVELLAS---GNPMVITYTWTKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAG-VYIC----EALNSQGTALLEIQVAVEYAPTITAVS------EGRSFV-------AGEPAVLA-CHIQAR--PLEAAHVRWSRDGYDLATRT-------ISSFENGTALLQIASVERSDIGNFTCIVDNQRGAPAAQNVLLVVQTAPEIDHSPGFTRYAARLGVRAQLICRSLASPQPSFI-W----------RRHGKDLKMQRRNKFK-------SVERQVDALNFESALLIENTSPDDYGQYECVVRNSLGQASTTLE 928          

Query: 1122 ESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSII-YQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGT-NRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPP---VIQLFSLPKIPNEGNFVQLQCQTSGGNP 1823
              Q  Q  C S+G + P +Q+ W     Y   VA S   +   R+           E+  K T   + NG  + C          L  E  + V++AP  + L    Q  + +  SV L+C T  SNP + I W       RP D +++       S+  G  + SS NI  T + Q    I  C   +  +   +   + +NVLYPP   ++  ++   I   G+ ++LQC ++GGNP
Sbjct:  265 RGQEVQIACRSRGGNPP-AQLTW-----YRNGVAISSPQRTSGRLS----------ENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAKVGD--SVQLSCVTAPSNPQARISW---SINGRPLDNSTYKTT----SSSDGGWVSSS-NISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNP 477          

Query:  777 LETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNP----------RPVV-SLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTI---MILVHYPPEKIELNEEPVDNQLESQS-KQFTCSSKGNSEPLSQIEW----TLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQD-HGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIE 2411
            L   + Y P  + L+ +N   Q ++G  +   C +   NP          RP+  S YK           S+N+ LT       F  +   ++ +   LT N +    + V YPP    L      + L S S  +  CSS G + P + ++W     + +A  +LV    T ++   V  ++  A+                    KC +    +++ L   K + V F P  + +   P+  +P  R+  L C + SSNP + I W++      P +  + +N+   P  + G    S+L ++    QD  G +Y C   +  +   + +   L++LYPP  +       P    FV ++     G P  +   +      P++ +Y +  +  P   I  N      + S       NI+  +  D G Y C+  N+ G  +  + + V ++P +   +  R +V +G   VL                      I AR  E  H    +   +   DL+  +R   +  N T  L I+S+   D G++ C V N RG  + +
Sbjct:  338 LNLTVLYAPKDVYLSGAN---QAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFIAVCHALNTE---LTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPT-LQWYKNDKIINAPSKLVDSKITSELSLLVNASDNNAI-------------------YKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRA-KLICDSSSSNPPAKISWWKD---GIPVEGLNLANR---PGLWGGSV--STLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFE------TPQSTTFVGVE-----GAPFHV---ELLASGNPMVITYTWTKDGLP---ISSNSLSGQRLISDGPR--LNISRLSRNDAGVYICEALNSQGTALLEIQVAVEYAPTITAVSEGRSFV-AGEPAVLAC-------------------HIQARPLEAAH----VRWSRDGYDLA--TRTISSFENGTALLQIASVERSDIGNFTCIVDNQRGAPAAQ 823          

Query:  852 GSLISFQCSSDNGNPRPVVSLYKKRFG-KKPQK---QVSANV---ILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLE-SQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGGIPETRSV-NLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPP-VIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHI---FNITAAAPKDRGWYSCQCENA--GGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            G  +   C S  GNP   ++ Y+       PQ+   ++S NV        DN A   C  + +   +P      + +L  Y P+ + L+     NQ +   S Q +C +   S P ++I W++    GR + +S T+K       ++ G +++  S + +T+  +   F   C  +   L   +     + V++ P+   L     G I  + S+  L C +   NP   +QW++ +     + I +       PS      I S L++   N  D+  IYKC V +A ++  +     L V +PP  +++  +PK    G   +L C +S  NP     ++  W            ++D    E   N    P ++      +    NIT     D   Y+CQ  N        E + L++ + P  +   S+      G+   +++  S  P +    W                         K  + +S NS     +++   +LNIS ++  D G Y CE  NS+G + +E Q+
Sbjct:  266 GQEVQIACRSRGGNPPAQLTWYRNGVAISSPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVL--YAPKDVYLSGA---NQAKVGDSVQLSCVT-APSNPQARISWSI---NGRPLDNS-TYKT---TSSSDGGWVSS--SNISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKND-----KIINA-------PSKLVDSKITSELSLL-VNASDNNAIYKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRAKLICDSSSSNPP----AKISW------------WKDGIPVE-GLNLANRPGLWGGSVSTLEMYVNITQDL--DGIVYTCQSHNEVLQRSVHETISLDILYPPKFETPQSTTFVGVEGAPFHVELLASGNPMVITYTW------------------------TKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAGVYICEALNSQGTALLEIQV 733          

Query:  786 NIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSANV------ILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMP---SNYSG---IAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISK--EYFLNVLYPPVIQLFSLPKIPNEG-NFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHH-HIFNITAAAPKDRGWYSCQCENA-GGVTVEFMFLNVYFSPILKHQTS-SRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQ 2417
            N+ Y PS  +LT  N       GS++  QCSS  GNP P +  YK  +    P K V + +      ++   DN A + C ++  +   P   + T+   VH+PPE ++++  P  N +     +  C S  +S P ++I W       +     E   +  R      G+++TLE  V +T  +  +G    C    Q  N + Q    + +     + ++  P+   P++     T F G      +++   +     P  IT    KD +P   ++ SG   I+    LNI   +R D G +Y C      +NS+ +   E  + V Y P I   S      EG +FV        G P++++    Q +  P+  ++     D  +   R        + SF +   +  I +    D G ++C  +N  G    + + L V  +P + H    +R   + G    L  +  + P+   I W          R +  D + Q  N+ K       +   ++  +N    L I + +  DYG Y C V NS GQ+S   +
Sbjct:  441 NVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKNDKIINAPSKLVDSKITSELSLLVNASDNNAIYKCKVQNAAIDIPLFATKTLG--VHFPPETVKISVVP-KNLVPGIRAKLICDSS-SSNPPAKISW------WKDGIPVEGLNLANRPGLWG-GSVSTLEMYVNIT--QDLDGIVYTC----QSHNEVLQRSVHETI----SLDILYPPKFETPQS-----TTFVGVEGAPFHVELLAS---GNPMVITYTWTKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAG-VYIC----EALNSQGTALLEIQVAVEYAPTITAVS------EGRSFV-------AGEPAVLA-CHIQAR--PLEAAHVRWSRDGYDLATRT-------ISSFENGTALLQIASVERSDIGNFTCIVDNQRGAPAAQNVLLVVQTAPEIDHSPGFTRYAARLGVRAQLICRSLASPQPSFI-W----------RRHGKDLKMQRRNKFK-------SVERQVDALNFESALLIENTSPDDYGQYECVVRNSLGQASTTLE 928          

Query: 1122 ESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSII-YQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGT-NRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPP---VIQLFSLPKIPNEGNFVQLQCQTSGGNP 1823
              Q  Q  C S+G + P +Q+ W     Y   VA S   +   R+           E+  K T   + NG  + C          L  E  + V++AP  + L    Q  + +  SV L+C T  SNP + I W       RP D +++       S+  G  + SS NI  T + Q    I  C   +  +   +   + +NVLYPP   ++  ++   I   G+ ++LQC ++GGNP
Sbjct:  265 RGQEVQIACRSRGGNPP-AQLTW-----YRNGVAISSPQRTSGRLS----------ENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAKVGD--SVQLSCVTAPSNPQARISW---SINGRPLDNSTYKTT----SSSDGGWVSSS-NISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNP 477          

Query:  777 LETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNP----------RPVV-SLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTI---MILVHYPPEKIELNEEPVDNQLESQS-KQFTCSSKGNSEPLSQIEW----TLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQD-HGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIE 2411
            L   + Y P  + L+ +N   Q ++G  +   C +   NP          RP+  S YK           S+N+ LT       F  +   ++ +   LT N +    + V YPP    L      + L S S  +  CSS G + P + ++W     + +A  +LV    T ++   V  ++  A+                    KC +    +++ L   K + V F P  + +   P+  +P  R+  L C + SSNP + I W++      P +  + +N+   P  + G    S+L ++    QD  G +Y C   +  +   + +   L++LYPP  +       P    FV ++     G P  +   +      P++ +Y +  +  P   I  N      + S       NI+  +  D G Y C+  N+ G  +  + + V ++P +   +  R +V +G   VL                      I AR  E  H    +   +   DL+  +R   +  N T  L I+S+   D G++ C V N RG  + +
Sbjct:  338 LNLTVLYAPKDVYLSGAN---QAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFIAVCHALNTE---LTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPT-LQWYKNDKIINAPSKLVDSKITSELSLLVNASDNNAI-------------------YKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRA-KLICDSSSSNPPAKISWWKD---GIPVEGLNLANR---PGLWGGSV--STLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFE------TPQSTTFVGVE-----GAPFHV---ELLASGNPMVITYTWTKDGLP---ISSNSLSGQRLISDGPR--LNISRLSRNDAGVYICEALNSQGTALLEIQVAVEYAPTITAVSEGRSFV-AGEPAVLAC-------------------HIQARPLEAAH----VRWSRDGYDLA--TRTISSFENGTALLQIASVERSDIGNFTCIVDNQRGAPAAQ 823          

Query:  852 GSLISFQCSSDNGNPRPVVSLYKKRFG-KKPQK---QVSANV---ILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLE-SQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGGIPETRSV-NLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPP-VIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHI---FNITAAAPKDRGWYSCQCENA--GGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            G  +   C S  GNP   ++ Y+       PQ+   ++S NV        DN A   C  + +   +P      + +L  Y P+ + L+     NQ +   S Q +C +   S P ++I W++    GR + +S T+K       ++ G +++  S + +T+  +   F   C  +   L   +     + V++ P+   L     G I  + S+  L C +   NP   +QW++ +     + I +       PS      I S L++   N  D+  IYKC V +A ++  +     L V +PP  +++  +PK    G   +L C +S  NP     ++  W            ++D    E   N    P ++      +    NIT     D   Y+CQ  N        E + L++ + P  +   S+      G+   +++  S  P +    W                         K  + +S NS     +++   +LNIS ++  D G Y CE  NS+G + +E Q+
Sbjct:  266 GQEVQIACRSRGGNPPAQLTWYRNGVAISSPQRTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVL--YAPKDVYLSGA---NQAKVGDSVQLSCVT-APSNPQARISWSI---NGRPLDNS-TYKT---TSSSDGGWVSS--SNISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKND-----KIINA-------PSKLVDSKITSELSLL-VNASDNNAIYKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRAKLICDSSSSNPP----AKISW------------WKDGIPVE-GLNLANRPGLWGGSVSTLEMYVNITQDL--DGIVYTCQSHNEVLQRSVHETISLDILYPPKFETPQSTTFVGVEGAPFHVELLASGNPMVITYTW------------------------TKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAGVYICEALNSQGTALLEIQV 733          

Query:  786 NIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSANV------ILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMP---SNYSG---IAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISK--EYFLNVLYPPVIQLFSLPKIPNEG-NFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHH-HIFNITAAAPKDRGWYSCQCENA-GGVTVEFMFLNVYFSPILKHQTS-SRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQ 2417
            N+ Y PS  +LT  N       GS++  QCSS  GNP P +  YK  +    P K V + +      ++   DN A + C ++  +   P   + T+   VH+PPE ++++  P  N +     +  C S  +S P ++I W       +     E   +  R      G+++TLE  V +T  +  +G    C    Q  N + Q    + +     + ++  P+   P++     T F G      +++   +     P  IT    KD +P   ++ SG   I+    LNI   +R D G +Y C      +NS+ +   E  + V Y P I   S      EG +FV        G P++++    Q +  P+  ++     D  +   R        + SF +   +  I +    D G ++C  +N  G    + + L V  +P + H    +R   + G    L  +  + P+   I W          R +  D + Q  N+ K       +   ++  +N    L I + +  DYG Y C V NS GQ+S   +
Sbjct:  441 NVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKNDKIINAPSKLVDSKITSELSLLVNASDNNAIYKCKVQNAAIDIPLFATKTLG--VHFPPETVKISVVP-KNLVPGIRAKLICDSS-SSNPPAKISW------WKDGIPVEGLNLANRPGLWG-GSVSTLEMYVNIT--QDLDGIVYTC----QSHNEVLQRSVHETI----SLDILYPPKFETPQS-----TTFVGVEGAPFHVELLAS---GNPMVITYTWTKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAG-VYIC----EALNSQGTALLEIQVAVEYAPTITAVS------EGRSFV-------AGEPAVLA-CHIQAR--PLEAAHVRWSRDGYDLATRT-------ISSFENGTALLQIASVERSDIGNFTCIVDNQRGAPAAQNVLLVVQTAPEIDHSPGFTRYAARLGVRAQLICRSLASPQPSFI-W----------RRHGKDLKMQRRNKFK-------SVERQVDALNFESALLIENTSPDDYGQYECVVRNSLGQASTTLE 928          

Query: 1122 ESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSII-YQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGT-NRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPP---VIQLFSLPKIPNEGNFVQLQCQTSGGNP 1823
              Q  Q  C S+G + P +Q+ W     Y   VA S   +   R+           E+  K T   + NG  + C          L  E  + V++AP  + L    Q  + +  SV L+C T  SNP + I W       RP D +++       S+  G  + SS NI  T + Q    I  C   +  +   +   + +NVLYPP   ++  ++   I   G+ ++LQC ++GGNP
Sbjct:  265 RGQEVQIACRSRGGNPP-AQLTW-----YRNGVAISSPQRTSGRLS----------ENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAKVGD--SVQLSCVTAPSNPQARISW---SINGRPLDNSTYKTT----SSSDGGWVSSS-NISLTIDSQSRTFIAVCHALNTELTQNVVGSHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNP 477          

Query: 1614 SSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEI----RQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSIT-AYDYGDYFCEVSNSRGQSS-------------IEFQIFPTNDISISESNIRLQFNANKATVYF 2498
            SSL +    R+D G +Y+C+V +   +++   E  L    P +I  F + +    G  + L+C  SG  P      QF W             + QP  ++    R    Q  DM      H+ NI+   P D G Y C   N+ G       LNVY  P ++      +   +G +I++   ++ YP + +I+W             E  HQ           +L+ ++ ++L  V    QL I ++    D G Y C V +  G+ +             IE   FP N      + I    ++    +YF
Sbjct:  400 SSLLVQNVGRRDRG-VYQCLVENQRASAQAMAELKLGDTVPELIYTF-IEQNVRPGPLISLKCSASGSPPP-----QFAWLL-----------DSQPIMDVSLHHRFAIGQFVDMSGDVISHL-NISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVR--AIGPIKAVAGEDIIVHCPFAGYP-VEQIRW-------------EKAHQ-----------ELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYF 666          

Query: 1614 SSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEI----RQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSIT-AYDYGDYFCEVSNSRGQSS-------------IEFQIFPTNDISISESNIRLQFNANKATVYF 2498
            SSL +    R+D G +Y+C+V +   +++   E  L    P +I  F + +    G  + L+C  SG  P      QF W             + QP  ++    R    Q  DM      H+ NI+   P D G Y C   N+ G       LNVY  P ++      +   +G +I++   ++ YP + +I+W             E  HQ           +L+ ++ ++L  V    QL I ++    D G Y C V +  G+ +             IE   FP N      + I    ++    +YF
Sbjct:  400 SSLLVQNVGRRDRG-VYQCLVENQRASAQAMAELKLGDTVPELIYTF-IEQNVRPGPLISLKCSASGSPPP-----QFAWLL-----------DSQPIMDVSLHHRFAIGQFVDMSGDVISHL-NISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVR--AIGPIKAVAGEDIIVHCPFAGYP-VEQIRW-------------EKAHQ-----------ELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYF 666          

Query:  405 QYKFKVFKTF---EGEWKCQYGGQSS------RSLSLKV---SDKPFIKSLAMTPKPAWKGKQLNITC---QVMPMTGITGIFIQRILDDGTVENIANAIPY-------KVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNI---YYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKY-----------DNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVK----KANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLN-QEKQIKVVFAPNHISL-IPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPV-IQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSF---HHHHIFNITAAAPKDRGWYSCQCENAGGVTVE----FMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            QY  ++       +G ++CQ G   S      R++ L V   S +P+ +    + +P  +G+Q  +TC      P   IT      +  DG  E +  +  Y       K+      +TI+A   D   ++ C     +   + + LET +    YFP Q  +      ++ + GS +   C S  GN  P+ +L+  + G+        + +  +            DN A   C       +SP   + T+ +L  + P ++ L        +E +    +CS+  ++ P+  I W L             FK L R +    + + G + T+ S +   + R+ NG  ++C    +G    + +  ++ V + P  + L  P P   +    ++ L CF+   NP+  + W +         +   ++K +  S+  G++    L +H +   D+   Y+C  S+      +S +    VL+P V +++ +  K    G  + L C     NP+    +   W   PVI     K  DQ                S     HH    IT             C+    V  E    F  L+V F P    +    V V       L  K S+ P     +W  +    +  R                     P   F      S   L I +++  D GDY  E SN+ G +  + ++
Sbjct:   88 QYHLQILDVTLEDDGPYECQVGRSESSRPIVSRTVWLNVQIPSSQPYFQ--LESEEPWVEGEQYTVTCIAPDAKPPAEIT------MFRDG--EELLESESYTMSGSQDKLQNTHAEVTIRARSSDDTRRLTCRAKNPA---SPRALETGMTMKVYFPPQAPMIMGLENEEVKAGSFLKVVCMSYGGN--PLATLHWTKNGEVLSTSWDVDFVSRRASSVLKMEVKPEDNHAVLQCQSINQVTRSPMSLTRTLTVL--FEPAEVTLLGS--FEAVEGEEINLSCSTSSSNPPV-HIRWWL------------GFKELNRTEVTFAEGDNGGMMTV-SNLTHKVSREDNGLSLQCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKN------NKVVLTASKQV--SSERGVSRELLLILHPS---DNLATYRCDSSNK-AKKVLSTQTKFRVLFPAVSVKIVAKQKELRRGQTLDLDCLAGSSNPT----ANISWSLGPVI----LKGVDQAPKRAEFGGMSRTSKLSLTLESHHWRKRIT-------------CQAFSNVLSEGVNNFYSLDVLFPPEFSDEQPDEVQVIEDETATLPAKVSANPDEITCEWIFQGEKLVKER--------------------DPRYTF------SDWTLEIVNVSRRDGGDYIIECSNAEGSNRTKLRL 717          

Query:  624 DDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQC-IVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSAN--------VILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLE---SQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKC----SIIYQGLNMLNQEKQIKVVFA-------PNHISLIPDPQGGIPETRSVN---LTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGT-IYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDR-GWYSCQCENAGGVT--VEFMFLNVYFSPILK-----HQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLT-----IVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTN 2432
            D+G +  ++N + +KV +   G+++           QC   +  +  S+ +  E  +YY P ++ L +  P      GS +   C S  GNP   ++  K  +      KQVS+         +IL   DN A + C     S K+  + S      V +P   +++    V  Q E    Q+    C + G+S P + I W+L    G ++       + +  K+A  G ++   S + +TL   +   +I C    +++ +G+N       + V+F        P+ + +I D    +P   S N   +TC           +W       + E +    +     S++       +L I   +R+D G  I +C  +     +++     L+V Y P +++ S P   N G+   L C  +  NP  I+ S F WK+       E   E + +       Y++                   +DR G Y C  +N    T  VE   + V F+P L+      + +SR    + +N+V Q +    P++ + +W                  A+N       +DL  N R++ T      ++++I   I+   A DY  + C   NS G+ S++ Q+  TN
Sbjct:  383 DNGGMMTVSN-LTHKVSREDNGLSL-----------QCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKNNKVVLTASKQVSSERGVSRELLLILHPSDNLATYRC---DSSNKAKKVLSTQTKFRVLFPAVSVKI----VAKQKELRRGQTLDLDCLA-GSSNPTANISWSL----GPVILKG----VDQAPKRAEFGGMSRT-SKLSLTLESHHWRKRITCQAFSNVLSEGVNNF---YSLDVLFPPEFSDEQPDEVQVIEDETATLPAKVSANPDEITC-----------EWIF-----QGEKLVKERDPRYTFSDW-------TLEIVNVSRRDGGDYIIECSNAEGSNRTKLR----LDVQYSPTVRMKSDPVFVNIGDTADLLC-VADANP--ITSSMFSWKWMGEGERDELGEESEDDGTGVLTIYEV------------------TRDRAGVYQCTADNGISPTGSVEGQLI-VRFAPDLQKGPQWRKVASRGDGSNDANVVCQAQ--GVPRV-QFRW------------------AKN----GFPLDLG-NPRYEETTESTGTIHTSILTVINVSAALDYAIFTCTAHNSMGEDSLDIQLLSTN 919          

Query:  405 QYKFKVFKTF---EGEWKCQYGGQSS------RSLSLKV---SDKPFIKSLAMTPKPAWKGKQLNITC---QVMPMTGITGIFIQRILDDGTVENIANAIPY-------KVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNI---YYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKY-----------DNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVK----KANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLN-QEKQIKVVFAPNHISL-IPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPV-IQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSF---HHHHIFNITAAAPKDRGWYSCQCENAGGVTVE----FMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            QY  ++       +G ++CQ G   S      R++ L V   S +P+ +    + +P  +G+Q  +TC      P   IT      +  DG  E +  +  Y       K+      +TI+A   D   ++ C     +   + + LET +    YFP Q  +      ++ + GS +   C S  GN  P+ +L+  + G+        + +  +            DN A   C       +SP   + T+ +L  + P ++ L        +E +    +CS+  ++ P+  I W L             FK L R +    + + G + T+ S +   + R+ NG  ++C    +G    + +  ++ V + P  + L  P P   +    ++ L CF+   NP+  + W +         +   ++K +  S+  G++    L +H +   D+   Y+C  S+      +S +    VL+P V +++ +  K    G  + L C     NP+    +   W   PVI     K  DQ                S     HH    IT             C+    V  E    F  L+V F P    +    V V       L  K S+ P     +W  +    +  R                     P   F      S   L I +++  D GDY  E SN+ G +  + ++
Sbjct:  133 QYHLQILDVTLEDDGPYECQVGRSESSRPIVSRTVWLNVQIPSSQPYFQ--LESEEPWVEGEQYTVTCIAPDAKPPAEIT------MFRDG--EELLESESYTMSGSQDKLQNTHAEVTIRARSSDDTRRLTCRAKNPA---SPRALETGMTMKVYFPPQAPMIMGLENEEVKAGSFLKVVCMSYGGN--PLATLHWTKNGEVLSTSWDVDFVSRRASSVLKMEVKPEDNHAVLQCQSINQVTRSPMSLTRTLTVL--FEPAEVTLLGS--FEAVEGEEINLSCSTSSSNPPV-HIRWWL------------GFKELNRTEVTFAEGDNGGMMTV-SNLTHKVSREDNGLSLQCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKN------NKVVLTASKQV--SSERGVSRELLLILHPS---DNLATYRCDSSNK-AKKVLSTQTKFRVLFPAVSVKIVAKQKELRRGQTLDLDCLAGSSNPT----ANISWSLGPVI----LKGVDQAPKRAEFGGMSRTSKLSLTLESHHWRKRIT-------------CQAFSNVLSEGVNNFYSLDVLFPPEFSDEQPDEVQVIEDETATLPAKVSANPDEITCEWIFQGEKLVKER--------------------DPRYTF------SDWTLEIVNVSRRDGGDYIIECSNAEGSNRTKLRL 762          

Query:  624 DDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQC-IVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSAN--------VILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLE---SQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKC----SIIYQGLNMLNQEKQIKVVFA-------PNHISLIPDPQGGIPETRSVN---LTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGT-IYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDR-GWYSCQCENAGGVT--VEFMFLNVYFSPILK-----HQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLT-----IVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTN 2432
            D+G +  ++N + +KV +   G+++           QC   +  +  S+ +  E  +YY P ++ L +  P      GS +   C S  GNP   ++  K  +      KQVS+         +IL   DN A + C     S K+  + S      V +P   +++    V  Q E    Q+    C + G+S P + I W+L    G ++       + +  K+A  G ++   S + +TL   +   +I C    +++ +G+N       + V+F        P+ + +I D    +P   S N   +TC           +W       + E +    +     S++       +L I   +R+D G  I +C  +     +++     L+V Y P +++ S P   N G+   L C  +  NP  I+ S F WK+       E   E + +       Y++                   +DR G Y C  +N    T  VE   + V F+P L+      + +SR    + +N+V Q +    P++ + +W                  A+N       +DL  N R++ T      ++++I   I+   A DY  + C   NS G+ S++ Q+  TN
Sbjct:  428 DNGGMMTVSN-LTHKVSREDNGLSL-----------QCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKNNKVVLTASKQVSSERGVSRELLLILHPSDNLATYRC---DSSNKAKKVLSTQTKFRVLFPAVSVKI----VAKQKELRRGQTLDLDCLA-GSSNPTANISWSL----GPVILKG----VDQAPKRAEFGGMSRT-SKLSLTLESHHWRKRITCQAFSNVLSEGVNNF---YSLDVLFPPEFSDEQPDEVQVIEDETATLPAKVSANPDEITC-----------EWIF-----QGEKLVKERDPRYTFSDW-------TLEIVNVSRRDGGDYIIECSNAEGSNRTKLR----LDVQYSPTVRMKSDPVFVNIGDTADLLC-VADANP--ITSSMFSWKWMGEGERDELGEESEDDGTGVLTIYEV------------------TRDRAGVYQCTADNGISPTGSVEGQLI-VRFAPDLQKGPQWRKVASRGDGSNDANVVCQAQ--GVPRV-QFRW------------------AKN----GFPLDLG-NPRYEETTESTGTIHTSILTVINVSAALDYAIFTCTAHNSMGEDSLDIQLLSTN 964          

Query:  690 ITIKAAEPDLHNKVQCIVHTESEISTAKILETNI---YYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKY-----------DNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVK----KANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLN-QEKQIKVVFAPNHISL-IPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPV-IQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSF---HHHHIFNITAAAPKDRGWYSCQCENAGGVTVE----FMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            +TI+A   D   ++ C     +   + + LET +    YFP Q  +      ++ + GS +   C S  GN  P+ +L+  + G+        + +  +            DN A   C       +SP   + T+ +L  + P ++ L        +E +    +CS+  ++ P+  I W L             FK L R +    + + G + T+ S +   + R+ NG  ++C    +G    + +  ++ V + P  + L  P P   +    ++ L CF+   NP+  + W +         +   ++K +  S+  G++    L +H +   D+   Y+C  S+      +S +    VL+P V +++ +  K    G  + L C     NP+    +   W   PVI     K  DQ                S     HH    IT             C+    V  E    F  L+V F P    +    V V       L  K S+ P     +W                   Q    +K+R      S + L IVN         ++  D GDY  E SN+ G +  + ++
Sbjct:   68 VTIRARSSDDTRRLTCRAKNPA---SPRALETGMTMKVYFPPQAPMIMGLENEEVKAGSFLKVVCMSYGGN--PLATLHWTKNGEVLSTSWDVDFVSRRASSVLKMEVKPEDNHAVLQCQSINQVTRSPMSLTRTLTVL--FEPAEVTLLGS--FEAVEGEEINLSCSTSSSNPPV-HIRWWL------------GFKELNRTEVTFAEGDNGGMMTV-SNLTHKVSREDNGLSLQCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKN------NKVVLTASKQV--SSERGVSRELLLILHPS---DNLATYRCDSSNK-AKKVLSTQTKFRVLFPAVSVKIVAKQKELRRGQTLDLDCLAGSSNPT----ANISWSLGPVI----LKGVDQAPKRAEFGGMSRTSKLSLTLESHHWRKRIT-------------CQAFSNVLSEGVNNFYSLDVLFPPEFSDEQPDEVQVIEDETATLPAKVSANPDEITCEWIF-----------------QGEKLVKERDPRYTFSDWTLEIVN---------VSRRDGGDYIIECSNAEGSNRTKLRL 590          

Query:  624 DDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQC-IVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSAN--------VILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLE---SQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKC----SIIYQGLNMLNQEKQIKVVFA-------PNHISLIPDPQGGIPETRSVN---LTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGT-IYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDR-GWYSCQCENAGGVT--VEFMFLNVYFSPILK-----HQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLT-----IVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTN 2432
            D+G +  ++N + +KV +   G+++           QC   +  +  S+ +  E  +YY P ++ L +  P      GS +   C S  GNP   ++  K  +      KQVS+         +IL   DN A + C     S K+  + S      V +P   +++    V  Q E    Q+    C + G+S P + I W+L    G ++       + +  K+A  G ++   S + +TL   +   +I C    +++ +G+N       + V+F        P+ + +I D    +P   S N   +TC           +W       + E +    +     S++       +L I   +R+D G  I +C  +     +++     L+V Y P +++ S P   N G+   L C  +  NP  I+ S F WK+       E   E + +       Y++                   +DR G Y C  +N    T  VE   + V F+P L+      + +SR    + +N+V Q +    P++ + +W                  A+N       +DL  N R++ T      ++++I   I+   A DY  + C   NS G+ S++ Q+  TN
Sbjct:  256 DNGGMMTVSN-LTHKVSREDNGLSL-----------QCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKNNKVVLTASKQVSSERGVSRELLLILHPSDNLATYRC---DSSNKAKKVLSTQTKFRVLFPAVSVKI----VAKQKELRRGQTLDLDCLA-GSSNPTANISWSL----GPVILKG----VDQAPKRAEFGGMSRT-SKLSLTLESHHWRKRITCQAFSNVLSEGVNNF---YSLDVLFPPEFSDEQPDEVQVIEDETATLPAKVSANPDEITC-----------EWIF-----QGEKLVKERDPRYTFSDW-------TLEIVNVSRRDGGDYIIECSNAEGSNRTKLR----LDVQYSPTVRMKSDPVFVNIGDTADLLC-VADANP--ITSSMFSWKWMGEGERDELGEESEDDGTGVLTIYEV------------------TRDRAGVYQCTADNGISPTGSVEGQLI-VRFAPDLQKGPQWRKVASRGDGSNDANVVCQAQ--GVPRV-QFRW------------------AKN----GFPLDLG-NPRYEETTESTGTIHTSILTVINVSAALDYAIFTCTAHNSMGEDSLDIQLLSTN 792          

Query: 1449 IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSG--IAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEY-FLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPS 1826
            + E   + LTC T  S P+++++WF+ E             K     N SG    + SSL +H  NR D G  Y C V H  + +   +    L V Y P +++     +P EG +++LQC    GNPS
Sbjct:  116 VLEGDHITLTCVTSGSKPAADVRWFKNE----------MEVKGAKEVNASGKTFTVKSSLRLH-VNRDDDGVAYTCRVDHVALTATHEETTQVLEVHYAPYVEIRQSTNVPQEGQYLKLQC-VPKGNPS 232          

Query: 1455 ETRSVNLTCFTGSSNPSSNIQWFR----TEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS---EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNP 1823
            E   V LTC T  S P+++I+WFR     + G++  + T  S             + SS+++   +R+D G  Y C+V H  + S   ++++   L V YPP +++     +P EG + +L+C  S GNP
Sbjct:  127 EGEDVTLTCTTSGSKPAADIRWFRNDKEVQAGQKEVNATGRS-----------FTVRSSVHLK-VDRKDDGAAYTCVVEHVTLGSLPHQVTE--VLEVHYPPQVKIVHSVIVPQEGQYFKLECM-SKGNP 241          

Query:  690 ITIKAAEPDLHNKVQCIVHTESE-ISTAKILETNIYYFPSQLIL--TSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPN------LT------------SNTIMILVHYPPEKIELNEEPVDNQLES-QSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETR---SVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVIT-----SYEYKYEDQPNTEIRQNCYQLPDMFSFHHH-------HIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIV 2138
            + IK A+       + + H   E + T+ IL  N+ + P+++ +  +SS P K     S ++F C +   NP PV    + R+   P++ V  N I+T  D        M  ++ ++        LT            SN++ + V YPP+ + +   P D    +  S + TC S G + P  ++ W             +  K L    + + G + T E T+          ++   S I +    L    ++KV F    +++I   +    E R   ++ LTC TGSSNP+S I W +     + +D+         PS Y GI+  S + +   ++ D+G    C    + +N  ++  Y LN+L+PP               F+  Q       P+++   +      PV          Y +       IR   Y+        HH        I+N++ A   D G Y+  C N  G     + L+V +SP ++    + V + S + I 
Sbjct:  289 LNIKPADNMAVVSCEAVNHVTPETLKTSIIL--NVVFLPTEVTILGSSSGPEK-----SNLTFSCFTAASNP-PV----QIRWWLGPKELV--NTIVTISDAVHGGKVTMSNLTMEALREEHGMALTCEAFNEAILYTKSNSVTLSVQYPPQNVWIEAPPADKFFRAGTSVKMTCFSSGGNPP-PRLTWI------------KDTKSLSGGSQIHSGKIVTKEITIITVPSDNMATYRCNASNIGK-TPALTASTKLKVQFPAIDVNIISSAK----EYRRGSTIILTCVTGSSNPASTISWVKDGEQLKAQDLGRK------PSLYGGISSSSRVTLKAASK-DNGRRVSCEAFSSVLNEAVNTFYKLNILFPP--------------EFLDDQ-------PAVVQAVEHGAALIPVRVRANPPQINYTWSLWGEKLIRDGAYR--------HHLRGEGALEIWNVSRA---DSGVYNVTCVNKEGKNSIVIRLDVQYSPTIRSLGDTEVDLGSDAEIA 737          

Query:  690 ITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISF--------QCSSDNGNPRPVVSLYKKRF-------------GKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTC-SSKGNSEPLSQIEWTLFDAY-------GRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLP---KIPNEGNFVQLQCQTSGGNP 1823
            + I+ +E D   +  C V   SE+S   I  T +    + LI   +   ++Y  GS +++         C + +  P   +++ K                 K     + A VI    DN     CL    + ++P   S T+ +L  +PP    +      +    ++ +  C S  GN  PL+ ++W+  D           +V  S +   L  +K A+  A+ + E+   +T         +K SII            + VVF P  ++++    G  PE  ++  +CFT +SNP   I+W+   P +    I + S+     + + G    S+L +    R++HG    C   +  +    S    L+V YPP       P   K    G  V++ C +SGGNP
Sbjct:   83 LRIERSELDDDAEYHCQVG-RSEVSLGIISRTALI---NVLIPPKAPTFEEYAAGSRVTWVYGVEYTVTCQATDAKPAAALTIKKSGLEVSGDSSSNPGSRDKLENTAMVAKVIPQSSDNGKLLTCLALNPALQTPITVSFTMNVL--FPPNAPIIEGYIGPSVKAGETLKLICISLSGN--PLATLQWSKNDDVVSTRWETDEVVRASRSHLTLN-IKPADNMAVVSCEAVNHVT------PETLKTSII------------LNVVFLPTEVTILGSSSG--PEKSNLTFSCFTAASNPPVQIRWW-LGPKELVNTIVTISD-----AVHGGKVTMSNLTMEAL-REEHGMALTCEAFNEAILYTKSNSVTLSVQYPPQNVWIEAPPADKFFRAGTSVKMTCFSSGGNP 456          

Query: 1416 HISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            HIS    P   + E  ++ LTC +  S P+++I+WF+ +     ++IT         SN     + SSL   G +R+D G + +C V H  + S  +I+K+  L + Y P +++     +P EG  + L C++ G
Sbjct:  131 HISGFTSP---VMEGDTIQLTCKSSGSKPAADIRWFKND-----QEITDVQKIQQQDSNGKTFTVTSSLVFQG-DRKDDGAVIRCRVDHESLTSTPQIAKQ-VLEIHYTPTVRILPSTPLPQEGQPLILICESKG 255          

Query: 1416 HISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            HIS    P   + E  ++ LTC +  S P+++I+WF+ +     ++IT         SN     + SSL   G +R+D G + +C V H  + S  +I+K+  L + Y P +++     +P EG  + L C++ G
Sbjct:  128 HISGFTSP---VMEGDTIQLTCKSSGSKPAADIRWFKND-----QEITDVQKIQQQDSNGKTFTVTSSLVFQG-DRKDDGAVIRCRVDHESLTSTPQIAKQ-VLEIHYTPTVRILPSTPLPQEGQPLILICESKG 252          

Query: 1371 MLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKS-------GSNIVLQVKWSSYPKIHEIKWFIK 2195
            + +Q+ ++ V+  P    +   P+  +      NLTC   S+ P ++I WFR +  ++  D+ S    +++        + S L I  T+ QD G ++ C  S+  + S       LNV +PP + L   P+   EG  V+  C  +  NP I     ++W    +I               R + Y+    +SF    +              SC+  N  G T     ++V F+P        RV V+        GS++ L   W+  P +  + W  K
Sbjct:  105 LRSQKAKLTVLIPPEDPVIEGGPEILLRAGTPTNLTCRANSAKPPASIVWFR-DGNQQAGDVYS---TEVLADGKRATTV-SYLLISPTD-QDIGRVFTCRTSNEAIPSGKETSVKLNVHHPPTVTLSIHPQTVQEGERVRFTCSAT-ANPEI---KGYRWAKGGMIIE-----------SARDSSYETQVDYSFFTEPV--------------SCEVHNEVGSTNVSTLVDVQFAP--------RVVVEPKPTTTDMGSDVTLTCIWAGNPPL-TLTWTKK 342          

Query: 1371 MLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKS-------GSNIVLQVKWSSYPKIHEIKWFIK 2195
            + +Q+ ++ V+  P    +   P+  +      NLTC   S+ P ++I WFR +  ++  D+ S    +++        + S L I  T+ QD G ++ C  S+  + S       LNV +PP + L   P+   EG  V+  C  +  NP I     ++W    +I               R + Y+    +SF    +              SC+  N  G T     ++V F+P        RV V+        GS++ L   W+  P +  + W  K
Sbjct:  107 LRSQKAKLTVLIPPEDPVIEGGPEILLRAGTPTNLTCRANSAKPPASIVWFR-DGNQQAGDVYS---TEVLADGKRATTV-SYLLISPTD-QDIGRVFTCRTSNEAIPSGKETSVKLNVHHPPTVTLSIHPQTVQEGERVRFTCSAT-ANPEI---KGYRWAKGGMIIE-----------SARDSSYETQVDYSFFTEPV--------------SCEVHNEVGSTNVSTLVDVQFAP--------RVVVEPKPTTTDMGSDVTLTCIWAGNPPL-TLTWTKK 344          

Query: 1392 IKVVFAPNHISLIPDP-QGGIPETRSVNLTC-FTGSSNPSSNIQWFR-TE---PGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVL---YPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQP---NTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEV 2381
            I  V  P H++L P   + GI  T  V L+C  TGS  P   I+W+R TE   PG+    I   SN+ ++ S               + ++ H   Y+C    A   ++ ++++ + VL    P ++  FS  K+ N G    L C   G  P             P +T   +  +D+P   +   R N Y + D  +  H    N+T    +D G Y C   N+ G       +NV   P ++   +  +   +G + ++  +   YP  + IKW+          L  PD+  Q + E         N   KLT V   +          D G+Y C V
Sbjct:  366 ILTVIDPLHVTLTPKKLKTGIGST--VILSCALTGS--PEFTIRWYRNTELVLPGEA-ISIRGLSNETLLIS---------------SAQKSHSGAYQCF---ATRKAQTAQDFAIIVLEDGTPRIVSSFS-EKVVNPGEQFSLMCAAKGAPP-------------PTVT---WALDDEPVVRDGSHRTNQYTMSDGTTISH---MNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRGPPSIRAMRN--ITAVAGRDTLINCRVIGYP-YYSIKWY-------KDALLLPDNHRQVVFE---------NGTLKLTDVQKGM----------DEGEYLCSV 635          

Query: 1449 IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            + E   + LTC T  S P+++I+WF+ +  K  +D+     +D   +N     + S+L+    +R D G    C V H  +N+  +++ +  L + Y P +++      P EG  + L C++ G
Sbjct:  145 VMEGDLMQLTCKTSGSKPAADIRWFKND--KEIKDVKYLKEED---ANRKTFTVSSTLDFR-VDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVKIIPSTPFPQEGQALTLTCESKG 261          

Query: 1449 IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            + E   + LTC T  S P+++I+WF+ +  K  +D+     +D   +N     + S+L+    +R D G    C V H  +N+  +++ +  L + Y P +++      P EG  + L C++ G
Sbjct:  136 VMEGDLMQLTCKTSGSKPAADIRWFKND--KEIKDVKYLKEED---ANRKTFTVSSTLDFR-VDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVKIIPSTPFPQEGQALTLTCESKG 252          

Query: 1449 IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            + E   + LTC T  S P+++I+WF+ +  K  +D+     +D   +N     + S+L+    +R D G    C V H  +N+  +++ +  L + Y P +++      P EG  + L C++ G
Sbjct:  136 VMEGDLMQLTCKTSGSKPAADIRWFKND--KEIKDVKYLKEED---ANRKTFTVSSTLDFR-VDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVKIIPSTPFPQEGQALTLTCESKG 252          

Query: 1467 VNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            + LTC T  S P+++I+WF+ +  K  +D+     +D   +N     + S+L+    +R D G    C V H  +N+  +++ +  L + Y P +++      P EG  + L C++ G
Sbjct:  142 MQLTCKTSGSKPAADIRWFKND--KEIKDVKYLKEED---ANRKTFTVSSTLDFR-VDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVKIIPSTPFPQEGQALTLTCESKG 252          

Query: 1050 TIMILVHYPPEKIELNEEPVDNQLESQSK-QFTCSS-KGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIR----KYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVI---QLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKH-QTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKL 2303
            ++++ V YP +K+ +   P   +L + ++ +  C +  GN EP   + W       R V  S   ++ +  ++ + G++    ST    L+       N  K  C         L+   Q+ V F P +++++ +     P   ++NLTC + SSNP  N+ W +   G+R E + +   +    + + G A   S+ +  ++R DHG    C    A +   +S  Y LNVLY P     Q+  +  +      + +       NP   +   F W F      Y       P   I           S    H++N+T A   D G Y   C+N+ G     + L+V+++P ++  Q  + V V    +IV  V  +           I P      RL E D + Q++++M+K I   P  R ++
Sbjct:  432 SLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEP--SLMWY---KDSRTVTES---RLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKA-----GQLSASTQLAVQFPPTNVTILANASALRPGD-ALNLTCVSVSSNPPVNLSWDKE--GERLEGVAAPPRR----APFKGSAAARSVLLQVSSR-DHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAVEQGEALLPVSVSA---NP---APEAFNWTF----RGYRLSPAGGPRHRI----------LSSGALHLWNVTRA---DDGLYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANP----------ILPGMFNWERLGE-DEEDQSLDDMEK-ISRGPTGRLRI 803          

Query: 1368 NMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVI---QLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKH-QTSSRVYVKSGSNIVLQV 2147
              L+   Q+ V F P +++++ +     P   ++NLTC + SSNP  N+ W +   G+R ED+ +        + + G A   S+ +  ++R DHG    C      +   +S  Y  NVLYPP     Q+ ++  +  E   V L    S  NP   +   F W F      Y       P   I           S     ++N+T A   D G+Y   C+N+ G     + L+V+++P ++  +  + V V    +IV  V
Sbjct:  545 GQLSASTQLVVQFPPTNLTILANSSALRP-GDALNLTCVSISSNPPVNLSWDKE--GERLEDVAAKPQS----APFKGSAASRSVFLRVSSR-DHGQRVTCRAHSEALRETVSSFYRFNVLYPPEFLGEQVRAVTVV--EQGQVLLPVSVS-ANP---APEAFNWTF----RGYRLSPAGGPRHRI----------LSGGALQLWNVTRA---DDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALRDPTEVNVGGSVDIVCTV 777          

Query: 1416 HISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS--EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSG 1814
            HIS    P   + E  ++ LTC +  S P+++I+WF+ +     ++IT         SN     + SSL   G +R+D G + +C V H  + S  +I+K+  L + Y P +++     +P EG  + L C++ G
Sbjct:  128 HISGFTSP---VMEGDTIQLTCKSSGSKPAADIRWFKND-----QEITDVQKIQQQDSNGKTFTVTSSLVFQG-DRKDDGAVIRCRVDHESLTSTPQIAKQ-VLEIHYTPTVRILPSTPLPQEGQPLILICESKG 252          

Query: 1455 ETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYM-NSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHI--FNITAAAPKDRGWYSCQCENAGGVTVEFMFLNV 2069
            E     L C T  S P++NI+W+     K PE++       +   N     + S +    T + D G    C V H  + +S  S  + + V Y P  ++ S P +P EG+ ++LQC   G                PV  +Y ++ E+           ++P + +   + +  FN+      D G Y+C+  N  G  +    L+V
Sbjct:  139 ENDKAKLRCTTSGSKPAANIKWY-----KGPEELEGAKTSVLEDGNGKTFTVKSFIEFDVT-KDDDGAEITCAVGHESLHDSAKSSSHKIQVQYKPTAKIESRPSMPREGDKLRLQCDAYGN---------------PVPDNYVWERENG----------EVPLLANIEGNSLVFFNLNKT---DSGTYTCKASNTLGTFITHYKLDV 312          

Query: 1119 LESQSKQFTCSSKGNSEPLSQIEWTL-------FDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLI---PDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGK-RPEDI----TSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYP---PVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENA--GGVTVEFMFLNVYFSPI---------LKHQTSSRVYVKS-GSNIVLQVKW 2153
            +  +S  F CS++ + EP+   +W         +   G L  H   F  +++         N  E  +K+T +   +  + +C +++     +  +  + ++  P  +      P+    + E   +N+TC   +  P   + W+    GK    D+    T H NK           +++SL +  ++R DHG +  C       +  I+    L+VL+P   P +++   P     G+ V + C  +GGNP             P +  Y      Q ++ +     ++ +++SF         A+   +   Y C+  N+  G    + M L V + P          +++ +S+ +  KS  SN   Q+ W
Sbjct:   31 IAGESITFRCSAEKSPEPIVYSQWKSNTGSLLGYHQEGILPGHQGRFSYIKQ---------NAEELHLKITHVNLDDDGEYECQMLHPEEGPIRAKSFLNIIVPPQLVYFSNYQPNSIIAVKENTPLNITCVVPNVKPEPEVLWYMD--GKVMSRDVKQASTPHLNKTF--------TVYTSLVVQ-SDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEILRNPSALRSGDNVTIACSVTGGNPP------------PDVFWYHENKRLQSHSTLDTRSKEIKNIYSF--------IASQNDNMAEYECRANNSRTGNPKRKAMKLEVNYPPASVELFGESNIRYGSSANIQCKSLPSNPASQITW 365          

Query: 1293 STVKMTLIRKYNGFKIKCSIIYQGLNM-LNQEKQIKVVFAPNHISLIPDPQGG--IPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMM--PSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFS-LPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWK 1856
            ST+ + + R  N  ++KC      L+  L + + + V + P  + + P   G   +   +S  L C T SSNP+++I W   +  +  +D   H     +   +  +G  + + L+   T   D GT+  CI +H      ++  + LNV+YPP + +   +  + +EG+  + +  T  GNP+I   S +QW+
Sbjct:  541 STLALRVDRTMNTQRLKCEATNAALDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKSARLVCGTLSSNPAAHISW---QFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD-GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFK-ENLTVRGNPAI---SLWQWR 726          

Query:  126 MLLLPVVYVVAILSNPTFGFETRIEWTKGSFYPISKLLDSGTEQDLFCSIETEEQTHRMLLLCPLTVGLCMTDCIENKDISCNRKTISGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQRDISSPHWVEMSLEMMXXXXXXXXXXXXXXXXXXMTLILLKCRRKKPKDNYLENNSVATTNSHQRRQDYMLLNSPQNNSLLKNGCHCFSNYPLEMRSDNGSDHSVPSQNIYQTMMIRRKIRDNGEMSSVHSGGSCHSPDVVLTERTSINSASNPMVNGNPYPYSISNGPTKVNLLSGRLHSVDGLRQDPNMPEEYHMPQEMMFAAVDDGMNLSQTRIIPIPKHLSSEYPIFFQMNNAMIPKSYEMTMPSHYTSPMPQLECNNQXXXXXXXXXXXXXXXXXGTHEISNVENRKDNIENIQSDS 3608
            MLLLPVVYVVAILSNPTFGFETRIEWTKGSFYPISKLLDSGTEQDLFCSIETEEQTHRMLLLCPLTVGLCMTDCIENKDISCNRKTISGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQRDISSPHWVEMSLEMMIAVIIGVVGILVLLFVALMTLILLKCRRKKPKDNYLENNSVATTNSHQRRQDYMLLNSPQNNSLLKNGCHCFSNYPLEMRSDNGSDHSVPSQNIYQTMMIRRKIRDNGEMSSVHSGGSCHSPDVVLTERTSINSASNPMVNGNPYPYSISNGPTKVNLLSGRLHSVDGLRQDPNMPEEYHMPQEMMFAAVDDGMNLSQTRIIPIPKHLSSEYPIFFQMNNAMIPKSYEMTMPSHYTSPMPQLECNNQNSRESSSLTNSNSNQDSGTHEISNVENRKDNIENIQSDS
Sbjct:    1 MLLLPVVYVVAILSNPTFGFETRIEWTKGSFYPISKLLDSGTEQDLFCSIETEEQTHRMLLLCPLTVGLCMTDCIENKDISCNRKTISGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQRDISSPHWVEMSLEMMIAVIIGVVGILVLLFVALMTLILLKCRRKKPKDNYLENNSVATTNSHQRRQDYMLLNSPQNNSLLKNGCHCFSNYPLEMRSDNGSDHSVPSQNIYQTMMIRRKIRDNGEMSSVHSGGSCHSPDVVLTERTSINSASNPMVNGNPYPYSISNGPTKVNLLSGRLHSVDGLRQDPNMPEEYHMPQEMMFAAVDDGMNLSQTRIIPIPKHLSSEYPIFFQMNNAMIPKSYEMTMPSHYTSPMPQLECNNQNSRESSSLTNSNSNQDSGTHEISNVENRKDNIENIQSDS 1161          

Query:  300 MLLLCPLTVGLCMTDCIEN---KDISC------------NRKTI---SGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTV-----ENIANA---IPYKVD--QYSEGITIKAAEPD-------LHN-------KVQCIVHTESEISTAKILETNIYYFPSQL-ILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQV--------------SANVI-------LTKYDNKAEFFC------LMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCS-SKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGL-NMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFR-----------------TEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSI------ISQSQFQWK--FCPVITSYEYKYEDQPNT--------------EIR-----QNCYQLPDMFSF--HHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWF--------IKP-------NSRIS---------------ARLYEPDHQAQNINEM------KKRIDLSPNSRFKLTIV---------NSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIF 2423
            + LLCPL+ G+C+ DC       +I+C            +R ++   S +I +Q   +V     G W CQ  G SS    LKVSD P+I+SL  +  P   G  + +TC V P      +  QR  +   +     E I  A   +  KVD  + S  I  +  +PD       +H+         +C           + ++ +++Y P  + I T  +  +  + G+     C++++ NP P  +L ++R G   Q Q               + NV        LT+ DN A FFC      +ME ++       S+     V YPP+ I +  +PV +  ES SK FTC  +   S P S++ WT  D+ G L+   +   +    +           S + +   R  NG + +C+ IYQG   ML  E+ ++V FAPN++ L   P  G+ E++ ++LTC T S +P + I+WF                  T+P K P ++T  +  D  P  + G  + S L +  T R   GT+++C+V H  M   +  E+ L VLYP V+QL S P  P  G  V L CQTSGGNP I       +  +FQ    F     +   + ED   +              E R          L +M           N+T      RGWY+CQ  +AGGV+    FL++++ P +  +T SRV    G ++  ++   + P   E  WF        I P       N R S                 LY+   + +    +      K R  +  ++  +  IV         N T  L+ + + + D+GDY C++ +  G     FQ+ 
Sbjct:   32 VFLLCPLSTGVCLEDCKPTPNVHNITCEELEPQSARTGSDRSSMTRASRRIRYQIP-QVTGRHNGTWVCQNKGVSSERHELKVSDAPYIESLTASRNPVAAGSTVRLTCTVAPTPTAYELLRQRSWETNRLRQFKFEGIQFAWHRLRSKVDTGERSSPILNRVEQPDAFTSSLEVHDLRYEEGTVFECTAEDSRGRRAVRQIQLDVHYTPKSIHIETIPSHERPVQAGTRCHILCTAESSNPAPTFNLLRRRVG---QSQAYLMEDTALDGASLGTGNVARQAFAFQLTEQDNGASFFCEVITHGVMETVA------RSDGRQFNVTYPPQSIFVTMDPVGSVAESVSKVFTCQLNASGSNPPSELTWTQLDSAGALIPLKDDIHVQSTDQIVGEFGALIARSVLTVVARRSINGRRFECTAIYQGKKTMLRAEEILEVKFAPNNVGLTALPMDGVRESQRLDLTCATSSCHPPATIRWFEVPNHGSLEEEEGSWTIGTDPMK-PNELTDLAQMDTKPGKFGGTEVSSKLTVTKTYRLHQGTVFRCLVEHPAMEKPVISEHRLQVLYPTVVQLISHPPEPVVGQTVLLSCQTSGGNPLIGFTYTWFAADRFQLAGLFADSANNDSNRIEDASKSSMTATSSVRATGGVETRAAKRADGAPALKNMLRLLSQQEAYLNLTKVRLSQRGWYACQVASAGGVSHSTYFLDLFYQPQIDRRTRSRVQAHVGESVAFKLFIDANPPWAEAIWFQLNTDEQSIHPSLPTPLSNGRGSDTYFVGYHHNPYMGYDELYDYGMELKRKRRLVTGFGGKTRTQVGSDNSDRSNIVAGKGSGEKGNLTFILSFNEVRSEDFGDYVCQLRHKLGVQEFPFQLL 891          

Query:  300 MLLLCPLTVGLCMTDCIEN---KDISC------------NRKTI---SGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTV-----ENIANA---IPYKVDQYSEG--ITIKAAEPD-------LHN-------KVQCIVHTESEISTAKILETNIYYFPSQL-ILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKK---------------PQKQVSANVI---LTKYDNKAEFFC------LMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCS-SKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANP-GALNTLESTVKMTLIRKYNGFKIKCSIIYQGL-NMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFR-----------------TEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSI------ISQSQFQWK--FCPVITSYEYKYEDQPNT--------------EIR-----QNCYQLPDMFSF--HHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWF--------IKP-------NSRIS---------------ARLYEPDHQAQNINEM------KKRIDLSPNSRFKLTIV---------NSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIF 2423
            + LLCPL+ G+C+ DC       +I+C            +R ++   S +I +Q   +V     G W CQ  G SS    LKVSD P+I+SL     P   G  + +TC V P      +  QR  +   +     E I  A   +  KVD  +    I  +  +PD       +H+         +C           + ++ +++Y P  + I T     +  + G+     C++++ NP P  +L ++R G+                  + V+       LT+ DN A FFC      +ME ++       S+     V YPP+ I +  +PV +  ES SK FTC  +   S P S++ WT  D+ G L+   +   +    +     GAL    S + +   R  NG + +C+ IYQG   ML  E+ ++V FAPN++ L   P  G+ E++ ++LTC T S +P + I+WF                  T+P K P ++T  +  D  P  + G  + S L +  T R   GT+++C+V H  M   +  E+ L VLYP V+QL S P  P  G  V L CQTSGGNP +       +  +FQ    F     +   + +D   +              E R          L +M           N+T      RGWY+CQ  +AGGV+    FL++++ P +  +T SRV    G ++  ++   + P   E  WF        I P       N R S                 LY+   + +    +      K R  +  ++  +  I+         N T  L+ + + + D+GDY C++ +  G     FQ+ 
Sbjct:   32 VFLLCPLSTGVCLEDCKPTPNVHNITCEELEPQSARTGSDRSSMTRASRRIRYQIP-QVTGRHNGTWVCQNKGVSSERHELKVSDAPYIESLTANRNPVAAGSTVRLTCIVAPTPTAYELLRQRSRETNRLRQFKFEGIQFAWHRLRSKVDTGARRSPIVNRVEQPDAFTSSLEVHDLRYEEGTVFECTAEDSRGRRAVRQIQLDVHYTPKSIHIETIPAHDRPVQAGTRCHILCTAESSNPAPTFNLLRRRVGQSQAYLMEDTAFDGPSLGNENVARQAFAFQLTEQDNGASFFCEVITHGVMETVA------RSDGRQFNVTYPPQSIFVTMDPVGSVAESVSKVFTCQLNASGSNPPSELTWTQLDSAGALIPLKDDIHVQSTDQIVGEFGAL-IARSVLTVVARRSINGRRFECTAIYQGKKTMLRAEEILEVKFAPNNVGLTALPMDGVRESQRLDLTCATSSCHPPATIRWFEVPNHGSLEEEEGSWTIGTDPTK-PNELTDLAQMDTKPGKFGGTEVSSKLTVTKTYRLHQGTVFRCLVEHPAMEKPVISEHRLQVLYPTVVQLISHPPEPVVGQTVLLSCQTSGGNPLVGFTYTWFAADRFQLAGLFADSANNDSNRIQDASKSSMTATSSVRATGGVETRAAKRADGAPALKNMLRLLSQQEAYLNLTKVRLSQRGWYACQVASAGGVSHSTYFLDLFYQPQIDRRTRSRVQAHVGESVAFKLFIDANPPWAEAIWFQLNTDEQSIHPSLPTPLSNGRGSDTYFVGYHHNPYMGYDELYDYGMELKRKRRLVTGFGGKTRTQVGSDNSDRSNIIAGKGSGEQGNLTFILSFNEVRSEDFGDYVCQLRHKLGVQEFPFQLL 891          

Query:  357 KDISCNRKTISGQ-----------IVFQYK---------FKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQ-VMP--MTGIT-------GIFIQRILDDGTV-------------------------ENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQY--EIGSLISFQCSSDNGNPRPVVSLYKKRFG-------KKPQKQVSAN---------------VILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKG-NSEPLSQIEWTLFDAYGRLVAHSETFKILERVK--KANPGALNTLESTVKMTLIRKYNGFKIKCSIIY-QGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPE------------------DITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQW------KFCPVIT-SYEYKYEDQPNTEIRQNCYQ---LPDMF------------------SFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQ---------AQNIN-------EMKKRIDLSPNSRFKLTIV------------------------------NSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISI-SESNIRLQFNANKATVYFDPPTIGHFTHMSLRVC 2546
            +DISCN  + S +           I F YK          ++  +F G W C     SS    +  SD    +  +    P    K + + C  V P  MT IT        +  + ++DDGT+                         +   N+ P K++Q ++ +  KA       +++C + T+ +I   K L    +Y+PS+ +   +N    Y  ++G+++  +C+++ GNP P +SL ++RF        +   KQ++ +               V L++ DN A FFC +     KS    S+++   V +PP  + +   P     ES  K F+C +    S P + ++W   D+ G +++  E+ K+   V     N GA+ T  S + +   R  NG + +CS+++     +L  E  ++V+F+PN+I L   P  G+PE   + LTC T S +P + I+W    P K  E                  ++T  S  +    ++ G  + S+L I  T R    TIY+C+V+H  MN  +  E+ L +LYPP I + SLP  P     V L CQ  GGNPS  +   + W      +F  ++    + +  D P  +   N +    LP+ F                  + +H    N+T       GWY C+    GG +     L++++ P++  +T + V  + G +  L +   + P   E +WF     +  A       Q          Q++N       +   R+  +P +RF+  +                               N T  L  + +  +D+G Y C+V +  G     F +     I + +E +I +  + +  ++ F PP+   +T + LRVC
Sbjct:  125 QDISCNHFSFSQEYKNFDSRIKKSIKFPYKQIDIYRYTIDQINSSFNGSWICHTDRTSSGIHDIISSDLQHSERQSNYYIPLLSSKPIQVKCDFVSPTMMTNITESHMNNSSLRYKYVMDDGTINWRLELNSFNQLKTNETSNNDVFIHDKYLNSFPSKLNQSTDNVINKA-------QIECQI-TDKQIHRNKRLIDYEHYYPSKSVRLDTNLSPDYFVQVGTILKIKCTAEPGNPPPKLSLLRQRFDETKATVIQTKTKQLNQSNSFINIRKDIAQEFIVTLSEEDNGALFFCEVTSTGIKSSKARSDSVRYNVSFPPRALYVQSYPEGIIPESSQKMFSCQTDSMGSNPPAILKWQQLDSAGAVIS-LESLKMSVNVDFITQNNGAVVT-RSNLTVLATRALNGRRFECSVVFNDSKTLLRSEGFLEVMFSPNNIRLTAQPINGVPEAGRLELTCATSSCHPPAVIRWLEIPPDKIQEKNINNEEDIFQFTNLFSNELTDLSQLETNQGDFGGTKVLSTLIITKTYRSHQNTIYQCLVNHTGMNKPVLSEHRLKILYPPSIHIISLPNQPIARQSVTLFCQAIGGNPS--NDLTYAWFVEKSTQFSSLLNKGDDNQLNDDPYVKETNNLHSLSTLPNHFPSSSHITQRPEFGSMIQLTGYHDSQLNLTNIKLSQAGWYGCEVSGIGGSSHALHHLDLFYQPVMNRRTQTHVMAQIGESATLALYVDANPPWAEAEWFQIDTYKNEAGALHNGQQYIESQGYYGMQHVNYGHPQSYDSWHRVRRTPFNRFQSRLTTKDFSGELNSRQPIGQRKNIFASSGTGLNSNLTFLLRFTEVKPHDFGAYVCQVRHQLGVKDFTFYLIKKTGIGVLTEDSIEVIHHGSTTSILFSPPSKSPYTRLILRVC 1018          

Query:  852 GSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSAN------------------VILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCS-SKGNSEPLSQIEWTLFDAYG-RLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIY-QGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKR-----PEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQW------KFCPVITS-YEYKYEDQP---------NTEIRQNCYQL-----PDMFSFHHHHIF-----NITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISA------RLYE-------PDHQAQN-------------------INEMKKRIDLSPNSRFKLTIV-------NSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDI-SISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCL--------IQSSGT------------------------------------------CSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMT 2690
            G+ +  +CS D  N +  + L ++RFG+   + V  +                  +++T  DN+AE FC    ++G      ++T ++    PP  + +   P     ES +K+FTC  +   S P S I+W   D+ G RL          E++     G L+   ST+ +   R  NG + +C+ IY Q    L  E+ ++V+FAPN++ L   P GG+ E+  + LTC T S +P + I+WF   P  +       ++T  +  D  P  Y G ++ S+L +  T R    T+++C V H  +   I  E+ + VLYPP +QL ++P+ P  G  V L CQTSGGNP       F W      +F  ++ S +E    D+           T+ R+   QL     P++       +F     N T      RGWY+C+  ++GG      FL++++ PIL  +T  +V    G  +       + P   E+ WF   N   S+      R YE       P H   +                   +++ + RI +      K  IV       N T  L    +   D+G Y C+  +  G     FQ+    D   I  S+I +        V + PP    +T + LRVC           SS T                                          C +  +  P SG   + L  +  LYN+RL+++ G++ ++ T
Sbjct:   42 GTRVRIRCSMDGANSKVALVLLRQRFGQAKAESVDHSAGSTVIGTTQQHLEEDFFLVMTDQDNRAELFC---GVNGAG----TDTTLVRSTDPPNGVHVTASPAGPVTESITKKFTCRLNSSGSNPPSDIQWMQLDSAGARLPMTDVEITPTEQMSSPTGGYLS--HSTLTVNARRSSNGRRFECAAIYLQKRTSLRSEEILEVLFAPNNVRLTEKPMGGVRESDRLELTCKTSSCHPPAVIRWFEVPPKPKLSNQATNELTDLAQIDTSPGEYGGTSVSSTLVVSKTYRSQQHTVFRCQVEHPGLEKPIINEHRMQVLYPPTVQLITVPEEPVVGQTVTLSCQTSGGNPQ--DGFSFSWFAGSRSQFAELLDSKHENTASDKKPVRNDNRGLTTQQRKEFNQLSKSSPPEIDKMVSMTVFQDSQLNFTNVGLSQRGWYACEVSSSGGKAHASFFLDLFYQPILDRRTKQKVAAHLGETVSFVAHMEANPPSVEVTWFQLNNVVQSSAPSGYPRHYETFYASGYPYHGYDDFYEYRVRRASALNRTIRSLLDQGQSRIQVGNGMGEKHHIVAEKSDENNLTFSLRFMGVQTSDFGGYLCQARHRLGVKEFYFQLIKRPDTDGIIPSSINVTQRGPITIVRYKPPEKPPYTRIVLRVCRRDALLNGKTGSSATDTSRPIRQGVNVDKLENIGQPEDKDPTAKMKSNQVELGPSIGCEDYHVAKPQSGETEVQLSDAVQLYNFRLLMYQGTRAVRET 785          

Query: 1065 VHYPPEKIELNEEPVDNQLESQSK-QFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMP--SNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSS---YPKIHEIKWF 2189
            V+YPP+K+ L+  P    L S +  +  C S G + P  ++ W         + +++T ++  +  ++  G    +     +TL    N    +C    +   + + + ++ V F    + ++   Q  +   RS++L C  GSSNP +NI W            T  +  +  P  + + G+++ S L +     + HG    C    + ++  ++  Y LNVL+PP          P+E   VQ+    +   P ++S +       P   + E+ +  +   + R + Y  P+ ++     I+N+T    +D G Y  +C NA G     + L+V +SP +K +T   V+V  G    L  +  +    P +   KW 
Sbjct:  449 VYYPPQKVWLDAPPEGTLLRSGTTVRLVCFSSGGN-PTGRLTW---------MKNNKTVQVPSKHVESERG----VSREFLLTLQPSDNLATYRCDATNEAKEIRSAQIKLLVQFPAVSVKILVK-QKELRAGRSLSLDCLAGSSNPKANISWSLGS--------TRLNGVEQAPKRAEFGGLSVSSKLTLP-LGSEHHGKRVSCQAFSSLLSEGVNTFYVLNVLFPPEFA----EDQPSE---VQIVEDDTATLPIMVSAN-------PEDFTCEWLFHGEKVVKDRDHRYHFPEGWAL---EIWNVTR---RDAGNYRVECSNAEGKRSSIIKLDVQYSPTVKMKTDP-VFVNVGDTADLMCEADANPITPGMFSWKWM 784          

Query:  786 NIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYK-KRFGKKPQKQVSAN--------VILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKC----SIIYQGLNMLNQEKQIKVVFA-------PNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQW-FRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENA----GGVTVEFMFLNVYFSPILKHQTSSRVYVKSG---SNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTN 2432
            ++YY P ++ L +         G+ +   C S  GNP   ++  K  +  + P K V +         + L   DN A + C     + ++  + S  I +LV +P   +++  +  + +   +S    C + G+S P + I W+L          +    + +  K+A  G L ++ S + + L  +++G ++ C    S++ +G+N       + V+F        P+ + ++ D    +P   S N   FT         +W F  E   +  D   H      P  +       +L I    R+D G  Y+   S+A    + S    L+V Y P +++ + P   N G+   L C+ +  NP  I+   F WK+       E   + +         Y+              +T A     G Y C  +N     G V  + +   V F+P L+     R     G   +++ +  +    P++     F    +R+      P +  + + E              LT+VN +         A DY  + C   NS+G+ +++ Q+  T+
Sbjct:  448 SVYYPPQKVWLDAPPEGTLLRSGTTVRLVCFSSGGNPTGRLTWMKNNKTVQVPSKHVESERGVSREFLLTLQPSDNLATYRC---DATNEAKEIRSAQIKLLVQFPAVSVKILVKQKELR-AGRSLSLDCLA-GSSNPKANISWSL--------GSTRLNGVEQAPKRAEFGGL-SVSSKLTLPLGSEHHGKRVSCQAFSSLLSEGVNTF---YVLNVLFPPEFAEDQPSEVQIVEDDTATLPIMVSANPEDFT--------CEWLFHGEKVVKDRDHRYH-----FPEGW-------ALEIWNVTRRDAGN-YRVECSNA--EGKRSSIIKLDVQYSPTVKMKTDPVFVNVGDTADLMCE-ADANP--ITPGMFSWKWMGEGEVEELGEQSEDGATGLLTLYE--------------VTRA---QAGPYQCTADNEIAPPGSVVGQLV---VRFAPELQKGPQWRKVASRGDGSTDVDVLCQAEGVPRVT----FTWAKNRVPLDFPNPRYLERTVREGAIHTS-------TLTVVNVS--------AALDYAIFTCTARNSQGEDNLDIQLLSTS 942          

Query:  801 PSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILT--KYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPN----EGNFVQLQCQTSGGNPSIISQSQFQ 1850
            P + +  S +P  +   GS ++  CSSD   P    + +KK +    QK       +T  +  +  E+ C+     G   +  S    + V +PP+ + ++  P    +E  S   TCSS GN      +E+T +      VA  +TF  L ++   N G                    + KC    +     +    + V++ P  +S+   P G I E  SV LTC +   NP     W++                       S +A   +  I+  +  + G  YKC  S+ +   + S    LNVLYP   +  S+   P+    EG+ V L C +S GNP +   + F+
Sbjct:   45 PPKNVSVSISPSGEIVEGSSVTLTCSSDGNPPVQKYTWFKKVYKDVQQKWTGQIYSITNIRSADSGEYQCMATNTQG---SRYSEYKSLTVLHPPKSVSVSISPSGEIVEGSSVTLTCSSDGNPP----VEYTWYKGSSS-VATGKTFT-LNKISSVNSG--------------------EYKCRSSNKHGEKYSDTVTLNVLYPPKSVSVSISPSGKIVEGSSVTLTC-SSDGNPPVEYTWYKGS---------------------SSVATGKTFTINKISSVNSGE-YKCRSSNKH-GEKYSDTVTLNVLYPS--KSVSVSISPSGEIVEGSSVTLTC-SSDGNPPVQKYTWFK 344          

Query:  801 PSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSG 1601
            P + +  S +P  +   GS ++  CSSD GNP    + YK        K  + N I +   N  E+ C   + S K     S+T+ + V YPP+ + ++  P    +E  S   TCSS GN      +E+T +      VA  +TF I  ++   N G      S          +G K   ++    LN+L   K + V  +P+         G I E  SV LTC +  + P     WF+ + G  P   + HS    + S  SG
Sbjct:  135 PPKSVSVSISPSGEIVEGSSVTLTCSSD-GNPPVEYTWYKGSSSVATGKTFTLNKISSV--NSGEYKC---RSSNKHGEKYSDTVTLNVLYPPKSVSVSISPSGKIVEGSSVTLTCSSDGNPP----VEYTWYKGSSS-VATGKTFTI-NKISSVNSGEYKCRSS--------NKHGEKYSDTVT---LNVLYPSKSVSVSISPS---------GEIVEGSSVTLTCSSDGNPPVQKYTWFK-DGGSSPVG-SGHSYSFTLDSESSG 367          

Query:  801 PSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILT--KYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPN----EGNFVQLQCQTSGGNPSIISQSQFQ 1850
            P + +  S +P  +   GS ++  CSSD   P    + +KK +    QK       +T  +  +  E+ C+     G   +  S    + V +PP+ + ++  P    +E  S   TCSS GN      +E+T +      VA  +TF  L ++   N G                    + KC    +     +    + V++ P  +S+   P G I E  SV LTC +   NP     W++                       S +A   +  I+  +  + G  YKC  S+ +   + S    LNVLYP   +  S+   P+    EG+ V L C +S GNP +   + F+
Sbjct:   45 PPKNVSVSISPSGEIVEGSSVTLTCSSDGNPPVQKYTWFKKVYKDVQQKWTGQIYSITNIRSADSGEYQCMATNTQG---SRYSEYKSLTVLHPPKSVSVSISPSGEIVEGSSVTLTCSSDGNPP----VEYTWYKGSSS-VATGKTFT-LNKISSVNSG--------------------EYKCRSSNKHGEKYSDTVTLNVLYPPKSVSVSISPSGKIVEGSSVTLTC-SSDGNPPVEYTWYKGS---------------------SSVATGKTFTINKISSVNSGE-YKCRSSNKH-GEKYSDTVTLNVLYPS--KSVSVSISPSGEIVEGSSVTLTC-SSDGNPPVQKYTWFK 344          

Query:  801 PSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSG 1601
            P + +  S +P  +   GS ++  CSSD GNP    + YK        K  + N I +   N  E+ C   + S K     S+T+ + V YPP+ + ++  P    +E  S   TCSS GN      +E+T +      VA  +TF I  ++   N G      S          +G K   ++    LN+L   K + V  +P+         G I E  SV LTC +  + P     WF+ + G  P   + HS    + S  SG
Sbjct:  135 PPKSVSVSISPSGEIVEGSSVTLTCSSD-GNPPVEYTWYKGSSSVATGKTFTLNKISSV--NSGEYKC---RSSNKHGEKYSDTVTLNVLYPPKSVSVSISPSGKIVEGSSVTLTCSSDGNPP----VEYTWYKGSSS-VATGKTFTI-NKISSVNSGEYKCRSS--------NKHGEKYSDTVT---LNVLYPSKSVSVSISPS---------GEIVEGSSVTLTCSSDGNPPVQKYTWFK-DGGSSPVG-SGHSYSFTLDSESSG 367          

Query: 1455 ETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNS---EISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNP 1823
            E   V LTC T  S P+++I+WFR        D      K++  +  S   + S++++   +R+D G  Y C V H  +NS   ++++   L V Y P +++     +P EG + +L+C  S GNP
Sbjct:  143 EGEDVTLTCITTGSKPAADIRWFRN-------DKEVQGVKEVNATGRS-FTVRSAVHLR-VDRKDDGAAYTCSVEHVALNSTPHQVTE--VLEVHYAPKVEIVHSLIVPQEGQYFKLEC-VSKGNP 256          

Query: 1455 ETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEY-FLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPS 1826
            E   + LTC T  S P+++I+WFR E   +     + S K           + SSL +   +R D G  Y C V H  + S   +    L V Y P +++     +P EG+F++L+C    GNPS
Sbjct:  173 EGDHITLTCVTSGSKPAADIRWFRNEKEVKGAKEVNASGKTF--------TVRSSLELQ-VDRSDDGVAYTCKVDHVALPSTSQQATEVLEVHYAPRVEIRPSKSLPLEGHFLKLECVLK-GNPS 287          

Query: 1371 MLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIK 2195
            + ++  ++ V+  P+   +   P+  +    S NL+C +  + P S I+W +   G   E   S +    + ++   +   S L IH  +  D G  Y C+ S+  + S  S    LNV +PPV+ L   P+   EG+ V   CQ    NP I+    ++W    V+               R++ +      SF    +              SC   NA G T   + ++V F PIL  +   +  V   S++ L  KW+  P +  + WF K
Sbjct:  102 LRSRRAKLTVLIPPDDPVIDGGPEVLLNAGESYNLSCVSRGAKPPSTIEWLKD--GLPVEGAVSITE---VLADRKRVTTQSHLPIHPVD-TDTGRNYSCVTSNLAVPSGKSTTVTLNVHHPPVVTLSIEPRSVLEGDRVTFTCQAH-ANPPIMG---YRWAKGGVVLQ-----------GARESVFTTKADHSFFTEPV--------------SCLVFNAVGKTNVSILVDVQFGPILLVEPQPKT-VDVNSDVTLNCKWAGNPPL-TLTWFKK 339          

Query: 1467 VNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSH-AYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPS 1826
            + LTC T  S P+++++WFR E   +     +   K           + SSL +H  +R D G  Y C V H A   +       L V Y P +++    ++P EG +++L+C  S GNPS
Sbjct:  130 ITLTCITQGSKPAADLRWFRNEKEVKGAKEVNAEGKTF--------KVQSSLQLH-VDRNDDGVAYTCRVDHVALALAPQQATEVLEVQYAPRVEIIHSLEVPQEGQYLKLEC-VSKGNPS 240          

Query: 1467 VNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSG--IAIHSSLNIHGTNRQDHGTIYKCIVSH-AYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPS 1826
            + LTC T  S P+++++WFR E             K     N  G    + SSL +H  +R D G  Y C V H A   +       L V Y P +++    ++P EG +++L+C  S GNPS
Sbjct:   78 ITLTCITQGSKPAADLRWFRNE----------KEVKGAKEVNAEGKTFKVQSSLQLH-VDRNDDGVAYTCRVDHVALALAPQQATEVLEVQYAPRVEIIHSLEVPQEGQYLKLEC-VSKGNPS 188          

Query: 1467 VNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSH-AYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPS 1826
            + LTC T  S P+++++WFR E   +     +   K           + SSL +H  +R D G  Y C V H A   +       L V Y P +++    ++P EG +++L+C  S GNPS
Sbjct:  140 ITLTCITQGSKPAADLRWFRNEKEVKGAKEVNAEGKTF--------KVQSSLQLH-VDRNDDGVAYTCRVDHVALALAPQQATEVLEVQYAPRVEIIHSLEVPQEGQYLKLEC-VSKGNPS 250          

Query: 1467 VNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSH-AYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPS 1826
            + LTC T  S P+++++WFR E   +     +   K           + SSL +H  +R D G  Y C V H A   +       L V Y P +++    ++P EG +++L+C  S GNPS
Sbjct:  130 ITLTCITQGSKPAADLRWFRNEKEVKGAKEVNAEGKTF--------KVQSSLQLH-VDRNDDGVAYTCRVDHVALALAPQQATEVLEVQYAPRVEIIHSLEVPQEGQYLKLEC-VSKGNPS 240          

Query:  126 MLLLPVVYVVAILSNPTFGFETRIEWTKGSFYPISKLLDSGTEQDLFCSIETEEQTHRMLLLCPLTVGLCMTDCIENKDISCNRKTISGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQRDISSPHWVEMSLEMMXXXXXXXXXXXXXXXXXXMTLILLKCRRKKPKDNYLENNSVATTNSHQRRQDYMLLNSPQNNSLLKNGCHCFSNYPLEMRSDNGSDHSVPSQNIYQTMMIRRKIRDNGEMSSVHSGGSCHSPDVVLTERTSINSASNPMVNGNPYPYSISNGPTKVNLLSGRLHSVDGLRQDPNMPEEYHMPQEMMFAAVDDGMNLSQTRIIPIPKHLSSEYPIFFQMNNAMIPKSYEMTMPSHYTSPMPQLECNNQXXXXXXXXXXXXXXXXXGTHEISNVENRKDNIENIQSDS 3608
            MLLLPVVYVVAILSNPTFGFETRIEWTKGSFYPISKLLDSGTEQDLFCSIETEEQTHRMLLLCPLTVGLCMTDCIENKDISCNRKTISGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSK FTCSSKGNSEPLSQIEWTLFDAYGRLVA+SETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITA APKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQRDISSPHWVEMSLEMMIAVIIGVVGILVLLFVALMTLILLKCRRKKPKDNYLENNSVATTNSHQRRQDYMLLNSPQNNSLLKNGCHCFSNYPLEMRSDNGSDHSVPSQNIYQTMMIRRKIRDNGEMSSVHSGGSCHSPDVVLTERTSINSASNPMVNGNPYPYSISNGPTKVNLLSGRLHSVDGLRQDPNMPEEYHMPQEMMFAAVDDGMNLSQ RIIPIPK+LSSEYPIFFQMNNAMIPKSYEMTMPSHYTSPMPQLECNNQNSRESSSLTNSNSNQDSGTHEISNVENRKDNIENIQSDS
Sbjct:    1 MLLLPVVYVVAILSNPTFGFETRIEWTKGSFYPISKLLDSGTEQDLFCSIETEEQTHRMLLLCPLTVGLCMTDCIENKDISCNRKTISGQIVFQYKFKVFKTFEGEWKCQYGGQSSRSLSLKVSDKPFIKSLAMTPKPAWKGKQLNITCQVMPMTGITGIFIQRILDDGTVENIANAIPYKVDQYSEGITIKAAEPDLHNKVQCIVHTESEISTAKILETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKRFGKKPQKQVSANVILTKYDNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKHFTCSSKGNSEPLSQIEWTLFDAYGRLVANSETFKILERVKKANPGALNTLESTVKMTLIRKYNGFKIKCSIIYQGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFRTEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVIQLFSLPKIPNEGNFVQLQCQTSGGNPSIISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAVAPKDRGWYSCQCENAGGVTVEFMFLNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQRDISSPHWVEMSLEMMIAVIIGVVGILVLLFVALMTLILLKCRRKKPKDNYLENNSVATTNSHQRRQDYMLLNSPQNNSLLKNGCHCFSNYPLEMRSDNGSDHSVPSQNIYQTMMIRRKIRDNGEMSSVHSGGSCHSPDVVLTERTSINSASNPMVNGNPYPYSISNGPTKVNLLSGRLHSVDGLRQDPNMPEEYHMPQEMMFAAVDDGMNLSQARIIPIPKNLSSEYPIFFQMNNAMIPKSYEMTMPSHYTSPMPQLECNNQNSRESSSLTNSNSNQDSGTHEISNVENRKDNIENIQSDS 1161          

Query: 3707 MPLGVLQFAHSFRFHEYVSVFHVGRELLLQSHGLLRCSRVAGYEKGNRTEAEDENDENNIGSGTCVVIGFDSNG 3928
            MPLGVLQFAHSFRFHEYVSVFHVGRELLLQSHGLLRCSRVAGYEKGNRTEAEDE+DENNIGSGTCVVIGFDSNG
Sbjct:    1 MPLGVLQFAHSFRFHEYVSVFHVGRELLLQSHGLLRCSRVAGYEKGNRTEAEDEDDENNIGSGTCVVIGFDSNG 74          

Query: 2061 LNVYFSPILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSP----NSRFKLTI-VNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQIFPTNDISISESNIRLQFNANKATVYFDPPTIGHFTHMSLRVCLIQSSGTCSEMQINNPNSGHATISLPQSPSLYNYRLIVHNGSKVLQMTNIIQ 2702
            +N  F P L       +       I   V++ S PK  EI WF+  +++ S  ++       N  + ++ +D S       RF  +   N    L+IS I   D+G Y C++SN  G     F +   N   I + +I +  + NKA + + PP +GH++H+ L +C IQ S +C ++QI +P++G+    +  +   Y++ L V   S++   T  I+
Sbjct:  109 INSVFQPRLLSTFKKVIKTLPKEPINFVVQFISKPKEVEISWFLISDNKDSLSIW-------NNEKFERILDFSTIIVSEGRFHSSFNENGFTTLSISEIVENDFGLYVCKISNEIGFVYSYFWLVSENSCVIPQESITVLLDKNKAAITYQPPKVGHYSHVLLTMCEIQFSNSCQDIQIPHPSTGNVISPVLANIENYSFYLSVFQNSELKYKTESIR 320          

Query:  777 LETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKR-------FGKKPQKQVSANVILTKY--DNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKA--NPGALNTLESTVKMTLIRKYNGFKI-----------KCSIIY----QGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFR--TEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVI--QLFSLPKIPNEGNFVQLQCQTSGGNPSI--------------------------ISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENA-GGVTVEFMFLNVYFSP-ILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            ++ +I Y P +  +   N  K  ++       CS+  GNP P +  ++           ++   Q +  +I+T    DNK ++FC  + IS KS  L S+ + ++V +PP  I L           +  +  C++ G S P + + W L +  G++++      +     +   +  + NT+      +LI+ Y  F+I            C +      +   +L +  QI V F+P    +I +    I E +S  L     ++ P  +  WFR  T+  ++     S S   ++  N   + I +               Y  +V +    S+I+   +LN+ Y P+I    F   +I  +   ++   Q++  NP +                          I  +Q +WK  P  ++++Y  +    ++             F    +  I      D G Y C   N   G  V+ + L   F+P IL     S+     G  + L     S+P      +F + N+ +SA               K RI++   +RF+        QL I ++   D+G Y C+  N +G  S + ++
Sbjct:  491 VKLHITYSPEKPTIQGYNVGKPVKLNHNFEMTCSTIGGNPYPELQWFRDSKPIQSSFIAQQVGNQKTLKIIITPSINDNKVKYFCQAKSISLKSSPLNSDEVTLIVLFPPMTIGLKSLSGAEVENGKLLKLQCTA-GESNPPAVVRWKL-NRCGQMMSELGRRPVQTTCNEELLSASSSNTINGKFGGSLIQSY--FEIYPSWKDHLDYVDCEVFNPDYGEEHQVLRKRIQINVTFSPQFEGII-NYNFYIEEGQSQTLNLEPIANPPIKDYTWFRNSTKLSRKNVHSISTSKAKLIIRNAKPVDIDN---------------YTLVVVNDRGESQIT--IYLNITYQPIIIGDKFERKEIIRQNAELECSVQSNPANPHMSYKWTKLVPGKGYNDISSSDLVPAFTIGCNQAEWKGTPEKSNFKYFSKCMVKSQ-------------FEMTSLLIIYDVDRNDVGLYRCVVNNGIRGDVVKTIELTKEFTPQILSLPKFSKAAGNLGEEVSLFCYIRSHPSPKMTWFFGRYNTSVSA-------------NSKYRINI---TRFRTGFY--VAQLKIVNLQRTDHGSYVCKAENGKGSDSRKIEV 1043          

Query:  777 LETNIYYFPSQLILTSSNPLKQYEIGSLISFQCSSDNGNPRPVVSLYKKR-------FGKKPQKQVSANVILTKY--DNKAEFFCLMEKISGKSPNLTSNTIMILVHYPPEKIELNEEPVDNQLESQSKQFTCSSKGNSEPLSQIEWTLFDAYGRLVAHSETFKILERVKKA--NPGALNTLESTVKMTLIRKYNGFKI-----------KCSIIY----QGLNMLNQEKQIKVVFAPNHISLIPDPQGGIPETRSVNLTCFTGSSNPSSNIQWFR--TEPGKRPEDITSHSNKDMMPSNYSGIAIHSSLNIHGTNRQDHGTIYKCIVSHAYMNSEISKEYFLNVLYPPVI--QLFSLPKIPNEGNFVQLQCQTSGGNPSI--------------------------ISQSQFQWKFCPVITSYEYKYEDQPNTEIRQNCYQLPDMFSFHHHHIFNITAAAPKDRGWYSCQCENA-GGVTVEFMFLNVYFSP-ILKHQTSSRVYVKSGSNIVLQVKWSSYPKIHEIKWFIKPNSRISARLYEPDHQAQNINEMKKRIDLSPNSRFKLTIVNSTIQLNISSITAYDYGDYFCEVSNSRGQSSIEFQI 2420
            ++ +I Y P +  +   N  K  ++       CS+  GNP P +  ++           ++   Q +  +I+T    DNK ++FC  + IS KS  L S+ + ++V +PP  I L           +  +  C++ G S P + + W L +  G++++      +     +   +  + NT+      +LI+ Y  F+I            C +      +   +L +  QI V F+P    +I +    I E +S  L     ++ P  +  WFR  T+  ++     S S   ++  N   + I +               Y  +V +    S+I+   +LN+ Y P+I    F   +I  +   ++   Q++  NP +                          I  +Q +WK  P  ++++Y  +    ++             F    +  I      D G Y C   N   G  V+ + L   F+P IL     S+     G  + L     S+P      +F + N+ +SA               K RI++   +RF+        QL I ++   D+G Y C+  N +G  S + ++
Sbjct:  510 VKLHITYSPEKPTIQGYNVGKPVKLNHNFEMTCSTIGGNPYPELQWFRDSKPIQSSFIAQQVGNQKTLKIIITPSINDNKVKYFCQAKSISLKSSPLNSDEVTLIVLFPPMTIGLKSLSGAEVENGKLLKLQCTA-GESNPPAVVRWKL-NRCGQMMSELGRRPVQTTCNEELLSASSSNTINGKFGGSLIQSY--FEIYPSWKDHLDYVDCEVFNPDYGEEHQVLRKRIQINVTFSPQFEGII-NYNFYIEEGQSQTLNLEPIANPPIKDYTWFRNSTKLSRKNVHSISTSKAKLIIRNAKPVDIDN---------------YTLVVVNDRGESQIT--IYLNITYQPIIIGDKFERKEIIRQNAELECSVQSNPANPHMSYKWTKLVPGKGYNDISSSDLVPAFTIGCNQAEWKGTPEKSNFKYFSKCMVKSQ-------------FEMTSLLIIYDVDRNDVGLYRCVVNNGIRGDVVKTIELTKEFTPQILSLPKFSKAAGNLGEEVSLFCYIRSHPSPKMTWFFGRYNTSVSA-------------NSKYRINI---TRFRTGFY--VAQLKIVNLQRTDHGSYVCKAENGKGSDSRKIEV 1062