slc39a-6

Overview
Nameslc39a-6 (AKN21671.1)
Smed IDSMED30012117
Length (bp)1085
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc39a-6 (SMED30012117) t-SNE clustered cells

Violin plots show distribution of expression levels for slc39a-6 (SMED30012117) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc39a-6 (SMED30012117) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc39a-6 (SMED30012117) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30012117

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30012117SMESG000014388.1 SMESG000014389.1 SmedASXL_018185SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30012117SMESG000014388.1 SMESG000014389.1 SmedASXL_018185SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30012117SMESG000014389.1 Contig45750newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012117SMESG000014389.1 Contig45750uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012117SMESG000014389.1 Contig48950newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012117SMESG000014389.1 Contig48950uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30012117SMESG000014388.1 SMESG000014389.1 dd_Smed_v4_3110_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of slc39a-6 vs. Ensembl Human
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 300.442 bits (768), Expect = 5.943e-100
Identity = 178/342 (52.05%), Postives = 229/342 (66.96%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD-------HKVHGNGHSV--PMSL------ESDGQQLRHRREASSIGPPED----MPGKPNVS-------RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTW MTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P         A D Q++LA +        K    G ++  P S       +S+  +   R++A++ G PE     +P + N++       RR+ L+++AITIHN+PEGLAVGV FGA+ ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGHSSVFQALLGTFFTWGMTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 335
[Close]
BLAST of slc39a-6 vs. Ensembl Human
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 299.671 bits (766), Expect = 1.777e-99
Identity = 178/349 (51.00%), Postives = 229/349 (65.62%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLA-----TDHKVHGN-----------------GHSVPMSLESDGQQLRHRREASSIGPPED----MPGKPNVS-------RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTW MTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P         A D Q++LA     T  K   +                 G +  +S +S+  +   R++A++ G PE     +P + N++       RR+ L+++AITIHN+PEGLAVGV FGA+ ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGHSSVFQALLGTFFTWGMTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 342
[Close]
BLAST of slc39a-6 vs. Ensembl Human
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 124.405 bits (311), Expect = 2.097e-33
Identity = 81/207 (39.13%), Postives = 119/207 (57.49%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEE-GYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD-------HKVHGNGHSV--PMSL------ESDGQQLRHRREASSIGPPED----MPGKPNVS-------RRLLLMMIAITIHNIP 560
            ML   S + Q++LGT FTW MTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A    G+G+ +F P+ VG  +G+AFV+LAD   P         A D Q++LA +        K    G ++  P S       +S+  +   R++A++ G PE     +P + N++       RR+ L+++AITIHN+P
Sbjct:    1 MLQGHSSVFQALLGTFFTWGMTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVP 200
[Close]
BLAST of slc39a-6 vs. Ensembl Human
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 123.635 bits (309), Expect = 9.459e-33
Identity = 81/207 (39.13%), Postives = 119/207 (57.49%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEE-GYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD-------HKVHGNGHSV--PMSL------ESDGQQLRHRREASSIGPPE----DMPGKPNVS-------RRLLLMMIAITIHNIP 560
            ML   S + Q++LGT FTW MTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A    G+G+ +F P+ VG  +G+AFV+LAD   P         A D Q++LA +        K    G ++  P S       +S+  +   R++A++ G PE     +P + N++       RR+ L+++AITIHN+P
Sbjct:    1 MLQGHSSVFQALLGTFFTWGMTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVP 200
[Close]
BLAST of slc39a-6 vs. Ensembl Human
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 117.472 bits (293), Expect = 5.522e-31
Identity = 69/128 (53.91%), Postives = 94/128 (73.44%), Query Frame = 3 
Query:  417 MSLESDGQQLRHRREASSIGPPE----DMPGKPNVS-------RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLA 767
            +S +S+  +   R++A++ G PE     +P + N++       RR+ L+++AITIHN+PEGLAVGV FGA+ ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLA
Sbjct:   58 LSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLA 185
[Close]
BLAST of slc39a-6 vs. Ensembl Celegans
Match: zipt-11 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:P91354])

HSP 1 Score: 266.544 bits (680), Expect = 2.649e-87
Identity = 160/331 (48.34%), Postives = 218/331 (65.86%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAP--------VSSFSDFSVANDNQSSL---ATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGP---PEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            M+   +P+ Q++L   FTW +TALGA   L+   + +S+KLLD SLGF+AGVM AAS+WSLL+PA ++A E  +   +F+P+ +G  +G+ FV LAD   P         S  S  +  ++ + SL     D  V     SV        ++ R R  +  +G    P+ +P +      RR+LL+++A+T+HNIPEGLAVGV FG+ G++K AT   A NLA+GIG+QNFPEGLAVSLPL A G S  ++ WYGQLSG+VEP+A   G  AV  + P+LPYAL+FAAGAMIYVV DDIIPEAQ+ GNG LAS+  ++GF+VMMC+D+GLG
Sbjct:    1 MIRGINPIYQALLAATFTWGVTALGA--SLVFIMRHQSKKLLDISLGFAAGVMTAASFWSLLAPAIEIA-EADFEKWAFVPVAIGFAVGAGFVHLADTLLPSCVGDAGMTSLLSPPTRRSETEMSLMQAREDLDVAALARSV-------NEEHRERDRSVDMGSDKRPDVIPEEDYRQSWRRILLLILAVTVHNIPEGLAVGVGFGSAGKTKQATFESAFNLAIGIGLQNFPEGLAVSLPLAAFGHSKLKAFWYGQLSGMVEPIAALFGAAAVIFMEPVLPYALAFAAGAMIYVVVDDIIPEAQRNGNGKLASLGCIIGFLVMMCMDVGLG 321
[Close]
BLAST of slc39a-6 vs. Ensembl Celegans
Match: zipt-11 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:P91354])

HSP 1 Score: 266.544 bits (680), Expect = 2.649e-87
Identity = 160/331 (48.34%), Postives = 218/331 (65.86%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAP--------VSSFSDFSVANDNQSSL---ATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGP---PEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            M+   +P+ Q++L   FTW +TALGA   L+   + +S+KLLD SLGF+AGVM AAS+WSLL+PA ++A E  +   +F+P+ +G  +G+ FV LAD   P         S  S  +  ++ + SL     D  V     SV        ++ R R  +  +G    P+ +P +      RR+LL+++A+T+HNIPEGLAVGV FG+ G++K AT   A NLA+GIG+QNFPEGLAVSLPL A G S  ++ WYGQLSG+VEP+A   G  AV  + P+LPYAL+FAAGAMIYVV DDIIPEAQ+ GNG LAS+  ++GF+VMMC+D+GLG
Sbjct:    1 MIRGINPIYQALLAATFTWGVTALGA--SLVFIMRHQSKKLLDISLGFAAGVMTAASFWSLLAPAIEIA-EADFEKWAFVPVAIGFAVGAGFVHLADTLLPSCVGDAGMTSLLSPPTRRSETEMSLMQAREDLDVAALARSV-------NEEHRERDRSVDMGSDKRPDVIPEEDYRQSWRRILLLILAVTVHNIPEGLAVGVGFGSAGKTKQATFESAFNLAIGIGLQNFPEGLAVSLPLAAFGHSKLKAFWYGQLSGMVEPIAALFGAAAVIFMEPVLPYALAFAAGAMIYVVVDDIIPEAQRNGNGKLASLGCIIGFLVMMCMDVGLG 321
[Close]
BLAST of slc39a-6 vs. Ensembl Fly
Match: Zip48C (gene:FBgn0033665 transcript:FBtr0088038)

HSP 1 Score: 241.891 bits (616), Expect = 2.374e-77
Identity = 156/337 (46.29%), Postives = 224/337 (66.47%), Query Frame = 3 
Query:   39 PLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADK---YAPVSSF------------SDFSVANDNQSSLATDHKVHG--NGHSVPMSLESDGQQLRHRREASSIG---------PPEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGL 962
            P+TQ++LGTL TW +TA GA   L+ + +   R+ LD +LGF+AGVM+AAS+WSLL PA ++A     YG  +F+P+  G ++GS FV+  DK   Y  ++S             +D ++ +  ++ +A D       +  S  +S++  G+  R R++ +SI          P E    +  +S  +R++L+++AIT+HNIPEGLAVGV+FGA+G + ++T   ARNLA+GIGIQNFPEGLAVSLPL AAG S+ R++WYGQLSG+VEP+ G +G +AV   + ILPYALSFAAGAMIY+V DDI+PEA   GNG +A+   V GF++MMCL++ L
Sbjct:    7 PVTQALLGTLLTWGLTAAGA--ALVIFVRGNQRRSLDAALGFAAGVMIAASFWSLLKPAIEMAESSHLYGVYAFLPVAGGFLLGSIFVYGCDKLMSYLGLNSTNMMIQMTQSKAKADIAIEDSKRNGVAPDRLASKSLDSFSDCLSVQHSGES-RRRKKGASINEMEQCTYTTPEEQQRAEDALSQWKRIMLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESARNLAIGIGIQNFPEGLAVSLPLHAAGFSVKRALWYGQLSGMVEPIFGVLGAVAVTFANLILPYALSFAAGAMIYIVSDDILPEAHASGNGTIATWGTVSGFLIMMCLEVAL 340
[Close]
BLAST of slc39a-6 vs. Ensembl Zebrafish
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 302.753 bits (774), Expect = 2.633e-101
Identity = 173/322 (53.73%), Postives = 223/322 (69.25%), Query Frame = 3 
Query:   36 SPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVS-----------RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            SPL Q++LGTLFTWA+TA GA    +  S+   +++LDGSLGF+AGVMLAASYWSLL+PA ++A E G YG  +F+P+ VG  +G+ FV+LAD   P    +   +  D   +  +D       + +      +G+  + RR  S+ G  E+    P              RR++L+++AITIHNIPEGLAVGV FGA+G++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ +G+S  RS WYGQLSG+VEPLAG +G +AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  A+LGFVVMM LD+GLG
Sbjct:    6 SPLVQALLGTLFTWALTAAGAALVFIFSSR--QKRILDGSLGFAAGVMLAASYWSLLAPAIEMAEESGKYGDFAFLPVAVGFALGALFVYLADLMMP----ALVKMPTDPAGAQTSDPLAVRRSYKI-----ENGEVYQRRRGPSAGGHTEEQEVSPKAQEVRGQTGSSSWRRIVLLILAITIHNIPEGLAVGVGFGAIGKTPSATFESARNLAIGIGIQNFPEGLAVSLPLRGSGVSTWRSFWYGQLSGMVEPLAGLLGAVAVVLAEPLLPYALAFAAGAMVYVVLDDIIPEAQISGNGKLASWTAILGFVVMMSLDVGLG 316
[Close]
BLAST of slc39a-6 vs. Ensembl Zebrafish
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 299.671 bits (766), Expect = 4.751e-100
Identity = 172/325 (52.92%), Postives = 222/325 (68.31%), Query Frame = 3 
Query:   36 SPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVA-----------NDNQSSLATDHKVHG---NGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            SPL Q++LGTLFTWA+TA GA    +  S+   +++LDGSLGF+AGVMLAASYWSLL+PA ++A E G YG  +F+P+ VG  +G+ FV+LAD   P        +            +D +  +    +  G    GH+    +    Q++R +  +SS              RR++L+++AITIHNIPEGLAVGV FGA+G++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ +G+S  RS WYGQLSG+VEPLAG +G +AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  A+LGFVVMM LD+GLG
Sbjct:    6 SPLVQALLGTLFTWALTAAGAALVFIFSSR--QKRILDGSLGFAAGVMLAASYWSLLAPAIEMAEESGKYGDFAFLPVAVGFALGALFVYLADLMMPALVIDLLQLKASIRMGKKGDLSDLERGMFVYQRRRGPSAGGHTEEQEVSPKAQEVRGQTGSSSW-------------RRIVLLILAITIHNIPEGLAVGVGFGAIGKTPSATFESARNLAIGIGIQNFPEGLAVSLPLRGSGVSTWRSFWYGQLSGMVEPLAGLLGAVAVVLAEPLLPYALAFAAGAMVYVVLDDIIPEAQISGNGKLASWTAILGFVVMMSLDVGLG 315
[Close]
BLAST of slc39a-6 vs. Ensembl Zebrafish
Match: SLC39A11 (solute carrier family 39 member 11 [Source:HGNC Symbol;Acc:HGNC:14463])

HSP 1 Score: 253.447 bits (646), Expect = 6.083e-83
Identity = 147/266 (55.26%), Postives = 186/266 (69.92%), Query Frame = 3 
Query:  177 MLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAP--VSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            MLAASYWSLL+PA ++A E G YG  +F+P+ VG  +G+ FV+LAD   P  VS +  F +  +N             GH+    +    Q++R +  +SS              RR++L+++AITIHNIPEGLAVGV FGA+G++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ +G+S  RS WYGQLSG+VEPLAG +G +AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  A+LGFVVMM LD+GLG
Sbjct:    1 MLAASYWSLLAPAIEMAEESGKYGDFAFLPVAVGFALGALFVYLADLMMPALVSVWMIF-LFIENGEVYQRRRGPSAGGHTEEQEVSPKAQEVRGQTGSSSW-------------RRIVLLILAITIHNIPEGLAVGVGFGAIGKTPSATFESARNLAIGIGIQNFPEGLAVSLPLRGSGVSTWRSFWYGQLSGMVEPLAGLLGAVAVVLAEPLLPYALAFAAGAMVYVVLDDIIPEAQISGNGKLASWTAILGFVVMMSLDVGLG 252
[Close]
BLAST of slc39a-6 vs. Ensembl Xenopus
Match: slc39a11 (solute carrier family 39 member 11 [Source:NCBI gene;Acc:549475])

HSP 1 Score: 274.633 bits (701), Expect = 6.917e-90
Identity = 172/338 (50.89%), Postives = 228/338 (67.46%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSD--FSVANDNQSSLATDHKVHGNGHS-VPMSLE-----------SDGQQLRHRR--------EASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            M+   SP+ QS+LGTL TW +TA G+    +  S    R++LDGSLGF+AGVMLAASYWSLL+PA ++A     YGS +F+P  VG ++G+ FV+LAD+  P   FS+  +S+A  NQ S     K  G+ +    +S+             +G   + +R        + S + P E      +  RR++L+++AITIHNIPEGLAVGV FGA+G++ +AT   ARNLALGIGIQNFPEGLAVSLPL+ AG+S  ++ WYGQLSG+VEP+AG +G +A+ L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS   + GF+VMM LD+GLG
Sbjct:    1 MIEGYSPVLQSLLGTLLTWGLTAAGSALVFIFSSG--QRQILDGSLGFAAGVMLAASYWSLLAPAIEMAENSNQYGSFAFVPAAVGFLVGAGFVYLADQLMPALGFSEDPYSIATLNQDSKPIKEKDEGDLYEDKELSIRIGRGGFHQDKIENGDVYQRKRGTVSPLAEDFSMLNPREAAHKGGSSWRRIMLLILAITIHNIPEGLAVGVGFGAIGKTPSATFENARNLALGIGIQNFPEGLAVSLPLRGAGVSTWKAFWYGQLSGMVEPIAGLLGTIAISLAEPLLPYALAFAAGAMVYVVTDDIIPEAQACGNGKLASWTCIFGFIVMMSLDVGLG 336
[Close]
BLAST of slc39a-6 vs. Ensembl Mouse
Match: Slc39a11 (solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056])

HSP 1 Score: 289.271 bits (739), Expect = 8.652e-96
Identity = 175/342 (51.17%), Postives = 222/342 (64.91%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHK---VHGNGHSVPMSL-------------ESDGQQLRHRREASS-----IGPPEDMPGKPNVS-----RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P           D Q++LA +     +  +    P SL               +G+  + ++ A++     + P   M G          RR+ L+++AITIHNIPEGLAVGV FGAV ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  ++ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGYSSVVQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGATEDPQTALALNLDPALMKKSDPRDPTSLLFPESELSIRIDKRENGEVYQRKKVAATDLAEGVAPSGSMHGSSGQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 335
[Close]
BLAST of slc39a-6 vs. Ensembl Mouse
Match: Slc39a11 (solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056])

HSP 1 Score: 286.96 bits (733), Expect = 1.116e-94
Identity = 175/349 (50.14%), Postives = 220/349 (63.04%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVP----------------------MSLESDGQQLRHRRE------ASSIGPPEDMPGKPNVS-----RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P           D Q++LA +        S P                      +S + +  ++  R++      A  + P   M G          RR+ L+++AITIHNIPEGLAVGV FGAV ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  ++ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGYSSVVQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGATEDPQTALALNLDPALMKKSDPRDPTSLLFPESELSIRIGSTGLLSDKRENGEVYQRKKVAATDLAEGVAPSGSMHGSSGQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 342
[Close]
BLAST of slc39a-6 vs. Ensembl Mouse
Match: Slc39a11 (solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056])

HSP 1 Score: 280.796 bits (717), Expect = 7.228e-92
Identity = 177/372 (47.58%), Postives = 223/372 (59.95%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSV---------------------------------PMSL-------------ESDGQQLRHRREASS-----IGPPEDMPGKPNVS-----RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P      F  + D +   AT   + G   +V                                 P SL               +G+  + ++ A++     + P   M G          RR+ L+++AITIHNIPEGLAVGV FGAV ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  ++ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGYSSVVQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMPHLLQVSFLPSGDCKMPTATKTPLLGRTRAVELLGGNQGATEDPQTALALNLDPALMKKSDPRDPTSLLFPESELSIRIDKRENGEVYQRKKVAATDLAEGVAPSGSMHGSSGQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 370
[Close]
BLAST of slc39a-6 vs. Ensembl Mouse
Match: Slc39a11 (solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056])

HSP 1 Score: 114.39 bits (285), Expect = 7.661e-30
Identity = 78/207 (37.68%), Postives = 112/207 (54.11%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEE-GYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHK---VHGNGHSVPMSL-------------ESDGQQLRHRREASS-----IGPPEDMPGKPNVS-----RRLLLMMIAITIHNIP 560
            ML   S + Q++LGT FTWAMTA GA    +  S    R++LDGSLGF+AGVMLAASYWSLL+PA ++A    G+G+ +F P+ VG  +G+AFV+LAD   P           D Q++LA +     +  +    P SL               +G+  + ++ A++     + P   M G          RR+ L+++AITIHNIP
Sbjct:    1 MLQGYSSVVQALLGTFFTWAMTAAGAALVFIFSSG--QRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGATEDPQTALALNLDPALMKKSDPRDPTSLLFPESELSIRIDKRENGEVYQRKKVAATDLAEGVAPSGSMHGSSGQPGGSSWRRIALLILAITIHNIP 200
[Close]
BLAST of slc39a-6 vs. Ensembl Mouse
Match: Slc39a11 (solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056])

HSP 1 Score: 105.531 bits (262), Expect = 4.836e-27
Identity = 59/122 (48.36%), Postives = 79/122 (64.75%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEE-GYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD 383
            ML   S + Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A    G+G+ +F P+ VG  +G+AFV+LAD   P           D Q++LA +
Sbjct:    1 MLQGYSSVVQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGATEDPQTALALN 115
[Close]
BLAST of slc39a-6 vs. UniProt/SwissProt
Match: sp|Q2YDD4|S39AB_BOVIN (Zinc transporter ZIP11 OS=Bos taurus OX=9913 GN=SLC39A11 PE=2 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 7.013e-100
Identity = 181/348 (52.01%), Postives = 233/348 (66.95%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD------HKVHGNGHSV--P-------------MSLESDGQQLRHRREA---------SSIGPPEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML+  SP++Q++LGT FTW +TA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A+  G +GSL+F+P+ +G  +G+AFV++AD   P      +  A D Q++LA +       K    G  +  P             +S +S+  +   R+ A         ++ GPP     +P  S  RR+ L+++AITIHNIPEGLAVGV FGAVG++ +AT   ARNLALGIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YV+ DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLHGHSPVSQALLGTFFTWGLTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMAMSSGGFGSLAFLPVAIGFTLGAAFVYVADLLMP-----HWGAAEDPQTALALNLDPLLTKKSDAEGARMLFPESELSIRIGRAGLLSDKSENGEAYQRKRAVATDLAEGPAAPGPPRGSAAQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVGKTASATFESARNLALGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVIMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 341
[Close]
BLAST of slc39a-6 vs. UniProt/SwissProt
Match: sp|Q8N1S5|S39AB_HUMAN (Zinc transporter ZIP11 OS=Homo sapiens OX=9606 GN=SLC39A11 PE=2 SV=3)

HSP 1 Score: 299.671 bits (766), Expect = 8.535e-99
Identity = 178/349 (51.00%), Postives = 229/349 (65.62%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLA-----TDHKVHGN-----------------GHSVPMSLESDGQQLRHRREASSIGPPED----MPGKPNVS-------RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTW MTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P         A D Q++LA     T  K   +                 G +  +S +S+  +   R++A++ G PE     +P + N++       RR+ L+++AITIHN+PEGLAVGV FGA+ ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGHSSVFQALLGTFFTWGMTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 342
[Close]
BLAST of slc39a-6 vs. UniProt/SwissProt
Match: sp|Q6P6S2|S39AB_RAT (Zinc transporter ZIP11 OS=Rattus norvegicus OX=10116 GN=Slc39a11 PE=2 SV=1)

HSP 1 Score: 298.13 bits (762), Expect = 2.563e-98
Identity = 178/342 (52.05%), Postives = 226/342 (66.08%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEE-GYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHK---VHGNGHSVPMSL------------ESDGQQLRHRRE---------ASSIGPPEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S ++Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A    G+G+ +F P+ VG  +G+AFV+LAD   P           D Q++LA +     V  +    P SL            + +  ++  R++         A+  GP     G+P VS  RR+ L+++AITIHNIPEGLAVGV FGAV ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  ++ WYGQLSG+VEPLAG  G  AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGYSSVSQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAGEDPQTALALNLDPALVKKSDLKDPASLLFPERELSIRIDKRENGEVYQRKKLAATDFPEGAAPSGPVHGNSGQPGVSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFAVVLAEPVLPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 335
[Close]
BLAST of slc39a-6 vs. UniProt/SwissProt
Match: sp|Q8BWY7|S39AB_MOUSE (Zinc transporter ZIP11 OS=Mus musculus OX=10090 GN=Slc39a11 PE=1 SV=1)

HSP 1 Score: 286.96 bits (733), Expect = 7.809e-94
Identity = 175/349 (50.14%), Postives = 220/349 (63.04%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVP----------------------MSLESDGQQLRHRRE------ASSIGPPEDMPGKPNVS-----RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S + Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P           D Q++LA +        S P                      +S + +  ++  R++      A  + P   M G          RR+ L+++AITIHNIPEGLAVGV FGAV ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  ++ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGYSSVVQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGATEDPQTALALNLDPALMKKSDPRDPTSLLFPESELSIRIGSTGLLSDKRENGEVYQRKKVAATDLAEGVAPSGSMHGSSGQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 342
[Close]
BLAST of slc39a-6 vs. UniProt/SwissProt
Match: sp|Q28J44|S39AB_XENTR (Zinc transporter ZIP11 OS=Xenopus tropicalis OX=8364 GN=slc39a11 PE=2 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 2.018e-89
Identity = 172/338 (50.89%), Postives = 229/338 (67.75%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSD--FSVANDNQSSLATDHKVHGNGHS-VPMSLE-----------SDGQQLRHRR--------EASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            M++  SP+ QS+LGTL TW +TA G+    +  S    R++LDGSLGF+AGVMLAASYWSLL+PA ++A     YGS +F+P  VG ++G+ FV+LAD+  P   FS+  +S+A  NQ S     K  G+ +    +S+             +G   + +R        + S + P E      +  RR++L+++AITIHNIPEGLAVGV FGA+G++ +AT   ARNLALGIGIQNFPEGLAVSLPL+ AG+S  ++ WYGQLSG+VEP+AG +G +A+ L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS   + GF+VMM LD+GLG
Sbjct:    1 MIDGYSPVLQSLLGTLLTWGLTAAGSALVFIFSSG--QRQILDGSLGFAAGVMLAASYWSLLAPAIEMAENSNQYGSFAFVPAAVGFLVGAGFVYLADQLMPALGFSEDPYSIATLNQDSKPIKEKDEGDLYEDKELSIRIGRGGFHQDKIENGDVYQRKRGTVSPLAEDFSMLNPREAAHKGGSSWRRIMLLILAITIHNIPEGLAVGVGFGAIGKTPSATFENARNLALGIGIQNFPEGLAVSLPLRGAGVSTWKAFWYGQLSGMVEPIAGLLGTIAISLAEPLLPYALAFAAGAMVYVVTDDIIPEAQACGNGKLASWTCIFGFIVMMSLDVGLG 336
[Close]
BLAST of slc39a-6 vs. TrEMBL
Match: A0A0H3YJF2 (Slc39a-6 OS=Schmidtea mediterranea OX=79327 GN=slc39a-6 PE=2 SV=1)

HSP 1 Score: 612.838 bits (1579), Expect = 0.000e+0
Identity = 315/315 (100.00%), Postives = 315/315 (100.00%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLAVGVAFGAVGQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG
Sbjct:    1 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLAVGVAFGAVGQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 315
[Close]
BLAST of slc39a-6 vs. TrEMBL
Match: A0A452FRQ3 (Solute carrier family 39 member 11 OS=Capra hircus OX=9925 GN=SLC39A11 PE=4 SV=1)

HSP 1 Score: 307.375 bits (786), Expect = 1.649e-99
Identity = 181/341 (53.08%), Postives = 230/341 (67.45%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD------HKVHGNGH---------SVPMSLESDGQQLRHRREASSI--------GPPEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML+  SP++Q++LGT FTW +TA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +GSL+F+P+ VG  +G+AFV+LAD   P      +  A D Q +LA +       K    G          S+ +    +G+  + +R  ++         GPP     +P+ S  RR+ L+++AITIHNIPEGLAVGV FGAVG++ +AT   ARNLALGIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YV+ DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLHGHSPVSQALLGTFFTWGLTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGSLAFLPVAVGFTLGAAFVYLADLLMP-----QWGAAEDPQMALALNLDPVLTKKSDAEGARMLFPESELSIRIDKSENGEAYQRKRAVAADLAEGPAAPGPPRGSAAQPSGSSWRRIALLILAITIHNIPEGLAVGVGFGAVGKTASATFESARNLALGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVIMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 334
[Close]
BLAST of slc39a-6 vs. TrEMBL
Match: A0A452FRK2 (Solute carrier family 39 member 11 OS=Capra hircus OX=9925 GN=SLC39A11 PE=4 SV=1)

HSP 1 Score: 307.375 bits (786), Expect = 2.255e-99
Identity = 181/342 (52.92%), Postives = 231/342 (67.54%), Query Frame = 3 
Query:   18 AMLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD------HKVHGNGH---------SVPMSLESDGQQLRHRREASSI--------GPPEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            +ML+  SP++Q++LGT FTW +TA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +GSL+F+P+ VG  +G+AFV+LAD   P      +  A D Q +LA +       K    G          S+ +    +G+  + +R  ++         GPP     +P+ S  RR+ L+++AITIHNIPEGLAVGV FGAVG++ +AT   ARNLALGIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YV+ DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:   15 SMLHGHSPVSQALLGTFFTWGLTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGSLAFLPVAVGFTLGAAFVYLADLLMP-----QWGAAEDPQMALALNLDPVLTKKSDAEGARMLFPESELSIRIDKSENGEAYQRKRAVAADLAEGPAAPGPPRGSAAQPSGSSWRRIALLILAITIHNIPEGLAVGVGFGAVGKTASATFESARNLALGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVIMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 349
[Close]
BLAST of slc39a-6 vs. TrEMBL
Match: A0A3Q1LXE8 (Zinc transporter ZIP11 OS=Bos taurus OX=9913 GN=SLC39A11 PE=4 SV=1)

HSP 1 Score: 306.22 bits (783), Expect = 5.109e-99
Identity = 179/341 (52.49%), Postives = 231/341 (67.74%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD------HKVHGNGH---------SVPMSLESDGQQLRHRREASSI--------GPPEDMPGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML+  SP++Q++LGT FTW +TA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A+  G +GSL+F+P+ +G  +G+AFV++AD   P      +  A D Q++LA +       K    G          S+ +    +G+  + +R  ++         GPP     +P  S  RR+ L+++AITIHNIPEGLAVGV FGAVG++ +AT   ARNLALGIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  PILPYAL+FAAGAM+YV+ DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLHGHSPVSQALLGTFFTWGLTAAGA--ALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMAMSSGGFGSLAFLPVAIGFTLGAAFVYVADLLMP-----HWGAAEDPQTALALNLDPLLTKKSDAEGARMLFPESELSIRIDKSENGEAYQRKRAVATDLAEGPAAPGPPRGSAAQPGGSSWRRIALLILAITIHNIPEGLAVGVGFGAVGKTASATFESARNLALGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVIMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 334
[Close]
BLAST of slc39a-6 vs. TrEMBL
Match: A0A1U7QB30 (zinc transporter ZIP11 OS=Mesocricetus auratus OX=10036 GN=Slc39a11 PE=4 SV=1)

HSP 1 Score: 304.679 bits (779), Expect = 1.967e-98
Identity = 179/343 (52.19%), Postives = 231/343 (67.35%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATD-------HKVHGNGHS---VPMSL------ESDGQQLRHRREASSIGPPEDM---------PGKPNVS--RRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   S ++Q++LGT FTWAMTA GA   L+       R++LDGSLGF+AGVMLAASYWSLL+PA ++A   G +G+ +F P+ VG  +G+AFV+LAD   P         A D Q++LA +        K    G +   +P S       +S+  ++  R++ ++ G PE           PG+P VS  RR+ L+++AIT+HN+PEGLAVGV FGA+ ++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ AG S  R+ WYGQLSG+VEPLAG  G  AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  ++LGFVVMM LD+GLG
Sbjct:    1 MLQGYSSVSQALLGTFFTWAMTAAGA--ALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMP-----HLGAAEDPQTALALNLDPALMKKKSDPEGPTTLLLPESELSIRIDKSENGEVYQRKKVAAAGLPEGTAPSGPVQGNPGQPGVSSWRRIALLILAITLHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPVLPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG 336
[Close]
BLAST of slc39a-6 vs. Ensembl Cavefish
Match: SLC39A11 (solute carrier family 39 member 11 [Source:NCBI gene;Acc:111192387])

HSP 1 Score: 297.745 bits (761), Expect = 4.024e-99
Identity = 175/347 (50.43%), Postives = 228/347 (65.71%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLA--TDHKVHGNGHSVPMSLESDGQQLR-------------------HRREASSIG----------PPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   SP+ Q++LGTLFTW +TA GA    +  S+   +++LDGSLGF+AGVMLAASYWSLL+PA ++A E G YG+ +F P+ VG  +G+AFV+ AD   P        V  D  +SLA   D K        P++  ++ +++                     RR+ +  G          PPE      +  RR++L+++AITIHNIPEGLAVGV FGA G++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ +G+S  RS WYGQLSG+VEPLAG +G +AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  +++GF+VMM LD+GLG
Sbjct:    1 MLPDHSPVVQALLGTLFTWGLTAAGAALVFVFSSR--QKRILDGSLGFAAGVMLAASYWSLLAPAIEMAEESGKYGAFAFFPVAVGFALGAAFVYFADLMMPY-----LGVGADPHTSLALPADAKPLKEKMEDPVAPPTEAEEMSIRIGRAGIHSDKAENGEAYQRRKGAPSGHSEEQEVGTRPPEVSAASGSSWRRIVLLILAITIHNIPEGLAVGVGFGAAGKTSSATFESARNLAIGIGIQNFPEGLAVSLPLRGSGVSTWRSFWYGQLSGMVEPLAGLLGAVAVVLAEPLLPYALAFAAGAMVYVVVDDIIPEAQVSGNGKLASWTSIMGFIVMMSLDVGLG 340
[Close]
BLAST of slc39a-6 vs. Ensembl Cavefish
Match: SLC39A11 (solute carrier family 39 member 11 [Source:NCBI gene;Acc:111192387])

HSP 1 Score: 297.745 bits (761), Expect = 4.024e-99
Identity = 175/347 (50.43%), Postives = 228/347 (65.71%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEG-YGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLA--TDHKVHGNGHSVPMSLESDGQQLR-------------------HRREASSIG----------PPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            ML   SP+ Q++LGTLFTW +TA GA    +  S+   +++LDGSLGF+AGVMLAASYWSLL+PA ++A E G YG+ +F P+ VG  +G+AFV+ AD   P        V  D  +SLA   D K        P++  ++ +++                     RR+ +  G          PPE      +  RR++L+++AITIHNIPEGLAVGV FGA G++ +AT   ARNLA+GIGIQNFPEGLAVSLPL+ +G+S  RS WYGQLSG+VEPLAG +G +AV L  P+LPYAL+FAAGAM+YVV DDIIPEAQ  GNG LAS  +++GF+VMM LD+GLG
Sbjct:    1 MLPDHSPVVQALLGTLFTWGLTAAGAALVFVFSSR--QKRILDGSLGFAAGVMLAASYWSLLAPAIEMAEESGKYGAFAFFPVAVGFALGAAFVYFADLMMPY-----LGVGADPHTSLALPADAKPLKEKMEDPVAPPTEAEEMSIRIGRAGIHSDKAENGEAYQRRKGAPSGHSEEQEVGTRPPEVSAASGSSWRRIVLLILAITIHNIPEGLAVGVGFGAAGKTSSATFESARNLAIGIGIQNFPEGLAVSLPLRGSGVSTWRSFWYGQLSGMVEPLAGLLGAVAVVLAEPLLPYALAFAAGAMVYVVVDDIIPEAQVSGNGKLASWTSIMGFIVMMSLDVGLG 340
[Close]
BLAST of slc39a-6 vs. Ensembl Nematostella
Match: EDO40021 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S891])

HSP 1 Score: 298.516 bits (763), Expect = 5.191e-100
Identity = 181/349 (51.86%), Postives = 225/349 (64.47%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGY----GSLSFIPLTVGLVMGSAFVFLAD-------------KYAPVSSFSD---------FSV----ANDNQSSLA----TDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            M+   SP+TQ+ LGTLFTWA+TA GA   L+   K   RK+LDGSLGF+AGVMLAASYWSLL+PA ++A   GY    G LSFIP+++G  +G+AFV+ AD                PV S +           S+    AND + S+     T    +    S   + ESD Q+L   R                   R++L++IAIT+HNIPEGLAVGV FGA+ +S +AT   ARNLA+GIGIQNFPEGLAVSLPL+A+G+S+  S WYGQLSG+VEP+AG +G  AV L  P+LPYALSFAAGAM+YVV DDIIPEAQ  GNG LAS   +LGFV+MM LD+GLG
Sbjct:    1 MIRGYSPVTQAFLGTLFTWAVTAAGA--GLVFVFKSGQRKVLDGSLGFAAGVMLAASYWSLLNPAIEMAESSGYYGENGWLSFIPVSIGFTLGAAFVYGADYMMSYLGIESLAGSLTPVDSITKKQDPENEVHLSITNRQANDIKPSVTKRKMTTKPTNNITESEQNTTESDSQKLASWR-------------------RIMLLIIAITVHNIPEGLAVGVGFGAISKSPSATFENARNLAIGIGIQNFPEGLAVSLPLRASGISVWWSFWYGQLSGMVEPIAGILGAFAVTLAEPVLPYALSFAAGAMVYVVVDDIIPEAQTSGNGKLASWTTILGFVIMMSLDVGLG 328
[Close]
BLAST of slc39a-6 vs. Ensembl Nematostella
Match: EDO28740 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5M1])

HSP 1 Score: 207.994 bits (528), Expect = 2.593e-65
Identity = 131/315 (41.59%), Postives = 188/315 (59.68%), Query Frame = 3 
Query:   33 ESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQ----SKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            E P+  ++  +LFTW +TALGA   L+ + K  +R +LDG LGF+ GVM+AAS+WSLL+PA D +  EG+  +  IP  +G  +G+  +F  DK+ P                      +H N        E++ + ++     ++                  L+++AIT+HNIPEGLAVGV FGA        +T  I  A +LA+GIGIQNFPEG AV++PL+  G+S  +S WYGQLS +VEP+A  +G LAV   +PILPYAL+FAAGAMI+VV +++IPE Q+     +A++  + GF+VMM LD+GLG
Sbjct:   13 EHPILAALYASLFTWGLTALGA--SLVFFFKKMNRAVLDGMLGFTGGVMVAASFWSLLAPAIDNSPGEGF--VKVIPSALGFGLGALVLFGMDKWLP---------------------HLHINFK------ENEAEGVKTSWHKTT------------------LLVLAITLHNIPEGLAVGVLFGAASTMVGVEQTEMIVAAISLAIGIGIQNFPEGFAVAMPLRRQGVSRRKSFWYGQLSAIVEPMAAVLGALAVSFFTPILPYALAFAAGAMIFVVVEEVIPETQRDKYTDIATLGFIGGFIVMMSLDVGLG 278
[Close]
BLAST of slc39a-6 vs. Planmine SMEST
Match: SMESG000014389.1 (SMESG000014389.1)

HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0
Identity = 312/315 (99.05%), Postives = 315/315 (100.00%), Query Frame = 3 
Query:   21 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLXXXXXXXXXXQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 965
            MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAE+LAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDH+VHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLA+GVAFGAVGQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG
Sbjct:    1 MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSAGVMLAASYWSLLSPAEELAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYAPVSSFSDFSVANDNQSSLATDHRVHGNGHSVPMSLESDGQQLRHRREASSIGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLALGVAFGAVGQSKTATISKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAGFIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICAVLGFVVMMCLDMGLG 315
The following BLAST results are available for this feature:
BLAST of slc39a-6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC39A115.943e-10052.05solute carrier family 39 member 11 [Source:HGNC Sy... [more]
SLC39A111.777e-9951.00solute carrier family 39 member 11 [Source:HGNC Sy... [more]
SLC39A112.097e-3339.13solute carrier family 39 member 11 [Source:HGNC Sy... [more]
SLC39A119.459e-3339.13solute carrier family 39 member 11 [Source:HGNC Sy... [more]
SLC39A115.522e-3153.91solute carrier family 39 member 11 [Source:HGNC Sy... [more]
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BLAST of slc39a-6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
zipt-112.649e-8748.34Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S... [more]
zipt-112.649e-8748.34Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S... [more]
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BLAST of slc39a-6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Zip48C2.374e-7746.29gene:FBgn0033665 transcript:FBtr0088038[more]
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BLAST of slc39a-6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SLC39A112.633e-10153.73solute carrier family 39 member 11 [Source:HGNC Sy... [more]
SLC39A114.751e-10052.92solute carrier family 39 member 11 [Source:HGNC Sy... [more]
SLC39A116.083e-8355.26solute carrier family 39 member 11 [Source:HGNC Sy... [more]
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BLAST of slc39a-6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc39a116.917e-9050.89solute carrier family 39 member 11 [Source:NCBI ge... [more]
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BLAST of slc39a-6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Slc39a118.652e-9651.17solute carrier family 39 (metal ion transporter), ... [more]
Slc39a111.116e-9450.14solute carrier family 39 (metal ion transporter), ... [more]
Slc39a117.228e-9247.58solute carrier family 39 (metal ion transporter), ... [more]
Slc39a117.661e-3037.68solute carrier family 39 (metal ion transporter), ... [more]
Slc39a114.836e-2748.36solute carrier family 39 (metal ion transporter), ... [more]
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BLAST of slc39a-6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q2YDD4|S39AB_BOVIN7.013e-10052.01Zinc transporter ZIP11 OS=Bos taurus OX=9913 GN=SL... [more]
sp|Q8N1S5|S39AB_HUMAN8.535e-9951.00Zinc transporter ZIP11 OS=Homo sapiens OX=9606 GN=... [more]
sp|Q6P6S2|S39AB_RAT2.563e-9852.05Zinc transporter ZIP11 OS=Rattus norvegicus OX=101... [more]
sp|Q8BWY7|S39AB_MOUSE7.809e-9450.14Zinc transporter ZIP11 OS=Mus musculus OX=10090 GN... [more]
sp|Q28J44|S39AB_XENTR2.018e-8950.89Zinc transporter ZIP11 OS=Xenopus tropicalis OX=83... [more]
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BLAST of slc39a-6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YJF20.000e+0100.00Slc39a-6 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
A0A452FRQ31.649e-9953.08Solute carrier family 39 member 11 OS=Capra hircus... [more]
A0A452FRK22.255e-9952.92Solute carrier family 39 member 11 OS=Capra hircus... [more]
A0A3Q1LXE85.109e-9952.49Zinc transporter ZIP11 OS=Bos taurus OX=9913 GN=SL... [more]
A0A1U7QB301.967e-9852.19zinc transporter ZIP11 OS=Mesocricetus auratus OX=... [more]
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BLAST of slc39a-6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
SLC39A114.024e-9950.43solute carrier family 39 member 11 [Source:NCBI ge... [more]
SLC39A114.024e-9950.43solute carrier family 39 member 11 [Source:NCBI ge... [more]
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BLAST of slc39a-6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc39a-6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc39a-6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO400215.191e-10051.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO287402.593e-6541.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of slc39a-6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of slc39a-6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000014389.10.000e+099.05SMESG000014389.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30012117
GenBankAKN21671.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30012117 ID=SMED30012117|Name=slc39a-6|organism=Schmidtea mediterranea sexual|type=transcript|length=1085bp
CTATATAAATCTTATATGCAATGTTAAATTGGGAATCTCCTCTTACCCAG
TCGATATTGGGAACATTGTTTACGTGGGCCATGACAGCTCTGGGAGCCCT
CGGGTGTTTATTGCATTATTCAAAGATAGAAAGTAGGAAATTGCTGGATG
GGAGTCTCGGATTTTCTGCTGGAGTAATGCTTGCTGCATCGTATTGGTCA
TTGCTATCACCTGCAGAAGATTTGGCCGTCGAGGAAGGCTACGGTAGTCT
AAGCTTTATCCCTCTTACTGTTGGGCTTGTCATGGGGTCAGCATTTGTAT
TTCTGGCAGACAAATACGCTCCGGTGTCGTCGTTTTCTGATTTCTCGGTC
GCTAATGACAACCAGTCGTCATTGGCAACCGATCATAAGGTACATGGAAA
CGGTCATTCTGTTCCCATGAGTCTCGAATCCGATGGACAGCAACTAAGGC
ACCGTCGCGAGGCATCGTCGATTGGGCCGCCCGAGGACATGCCAGGAAAG
CCCAATGTCAGTCGGCGGCTGCTGCTAATGATGATTGCCATAACAATCCA
CAACATTCCCGAAGGGCTCGCTGTCGGTGTGGCATTCGGGGCCGTCGGCC
AATCCAAAACCGCCACGATATCAAAGGCCAGGAATTTGGCGCTCGGTATT
GGTATCCAGAACTTTCCAGAGGGTCTCGCTGTTAGTCTGCCGCTAAAAGC
CGCTGGGTTATCGCTGGGACGGAGCGTCTGGTACGGTCAACTGTCCGGTC
TCGTGGAGCCATTGGCTGGTTTCATTGGCTGCCTTGCGGTCCAGCTCATT
AGCCCCATTCTGCCATACGCGCTTTCATTTGCTGCCGGAGCGATGATTTA
TGTTGTTTTCGACGATATTATTCCAGAGGCTCAACAAATGGGCAACGGCC
ATCTGGCATCGATCTGTGCCGTGCTAGGATTCGTGGTGATGATGTGCCTG
GACATGGGCCTCGGCTGACAGATAATAATTGCCCAATGACAGCAACACGA
CAAACAACATCAACAACCAATCAGATCACTCTTTATGATTCTCATCGCTC
TGTTATTGCAAAAGATGTGTAAAGAATAAAATCTT
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protein sequence of SMED30012117-orf-1

>SMED30012117-orf-1 ID=SMED30012117-orf-1|Name=SMED30012117-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=316bp
MLNWESPLTQSILGTLFTWAMTALGALGCLLHYSKIESRKLLDGSLGFSA
GVMLAASYWSLLSPAEDLAVEEGYGSLSFIPLTVGLVMGSAFVFLADKYA
PVSSFSDFSVANDNQSSLATDHKVHGNGHSVPMSLESDGQQLRHRREASS
IGPPEDMPGKPNVSRRLLLMMIAITIHNIPEGLAVGVAFGAVGQSKTATI
SKARNLALGIGIQNFPEGLAVSLPLKAAGLSLGRSVWYGQLSGLVEPLAG
FIGCLAVQLISPILPYALSFAAGAMIYVVFDDIIPEAQQMGNGHLASICA
VLGFVVMMCLDMGLG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR003689ZIP
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
GO:0030001metal ion transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0046873metal ion transmembrane transporter activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003689Zinc/iron permeasePFAMPF02535Zipcoord: 18..311
e-value: 7.7E-25
score: 87.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 134..159
NoneNo IPR availablePANTHERPTHR11040ZINC/IRON TRANSPORTERcoord: 6..311
NoneNo IPR availablePANTHERPTHR11040:SF127ZINC TRANSPORTER ZIP11coord: 6..311
NoneNo IPR availableTMHMMTMhelixcoord: 13..35
NoneNo IPR availableTMHMMTMhelixcoord: 168..190
NoneNo IPR availableTMHMMTMhelixcoord: 293..315
NoneNo IPR availableTMHMMTMhelixcoord: 259..281
NoneNo IPR availableTMHMMTMhelixcoord: 74..96
NoneNo IPR availableTMHMMTMhelixcoord: 42..64