DUF3715 domain-containing protein

Overview
NameDUF3715 domain-containing protein
Smed IDSMED30012104
Length (bp)2228
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DUF3715 domain-containing protein (SMED30012104) t-SNE clustered cells

Violin plots show distribution of expression levels for DUF3715 domain-containing protein (SMED30012104) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DUF3715 domain-containing protein (SMED30012104) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DUF3715 domain-containing protein (SMED30012104) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30012104

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30012104SMESG000032087.1 SmedASXL_011179SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30012104SMESG000032087.1 SmedASXL_011179SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30012104SMESG000032087.1 SmedASXL_011180SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30012104SMESG000032087.1 SmedASXL_011180SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30012104SMESG000032087.1 dd_Smed_v4_5270_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
whole organismSMED30012104SMESG000032087.1 Contig30616newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30012104SMESG000032087.1 Contig30616uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Human
Match: TEX15 (testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738])

HSP 1 Score: 72.7886 bits (177), Expect = 2.493e-12
Identity = 56/216 (25.93%), Postives = 105/216 (48.61%), Query Frame = 1 
Query:  139 YISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGK-RKIVPMHDP-KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKY 780
            Y+S    NSRE   +   L++  +D + D    W      ++ N   E+ F  K  E+ E   +    + ++ FLA + +  + ++  +G+  +      LG  + G+++ ++ D+ L  +  + +  + +  ++FK + GK +KI P  D  KV L P+P FD H+    P  K+   +Q   S V+ YE++  +  PV +PR C P A +  K+
Sbjct:   47 YLSPCYTNSREYSFIHDTLNQCRLDVNCDLQSLWQFGDTKLVHNEELEKNFTAKRSEMRESGRHCRELEEQFCFLA-LPQSDVAQIYQNGISTRASTLKILGNPLLGIYMFRHVDIALNYSHSQSITVESI--LIFKVLFGKVKKIQPSVDKNKVSLDPSPNFDCHMSRNAPSLKDTIELQAYSSAVYFYEYSVLS-KPVDKPRQCLPYAVVTVKF 258
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Human
Match: TEX15 (testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738])

HSP 1 Score: 72.7886 bits (177), Expect = 2.579e-12
Identity = 56/216 (25.93%), Postives = 105/216 (48.61%), Query Frame = 1 
Query:  139 YISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGK-RKIVPMHDP-KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKY 780
            Y+S    NSRE   +   L++  +D + D    W      ++ N   E+ F  K  E+ E   +    + ++ FLA + +  + ++  +G+  +      LG  + G+++ ++ D+ L  +  + +  + +  ++FK + GK +KI P  D  KV L P+P FD H+    P  K+   +Q   S V+ YE++  +  PV +PR C P A +  K+
Sbjct:   51 YLSPCYTNSREYSFIHDTLNQCRLDVNCDLQSLWQFGDTKLVHNEELEKNFTAKRSEMRESGRHCRELEEQFCFLA-LPQSDVAQIYQNGISTRASTLKILGNPLLGIYMFRHVDIALNYSHSQSITVESI--LIFKVLFGKVKKIQPSVDKNKVSLDPSPNFDCHMSRNAPSLKDTIELQAYSSAVYFYEYSVLS-KPVDKPRQCLPYAVVTVKF 262
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Human
Match: TASOR (transcription activation suppressor [Source:HGNC Symbol;Acc:HGNC:30314])

HSP 1 Score: 52.7582 bits (125), Expect = 2.878e-6
Identity = 68/245 (27.76%), Postives = 103/245 (42.04%), Query Frame = 1 
Query:  148 EVPGNSRETYDMFQKL---SKTFVD--NSFDFS-------QSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDP-----------KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLV----------FLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            ++P  SRE   +FQ L   S+ F D  N    S        +++ ++A ++ N L E+EF EK +EL+      +     Y FL  +    +  +   GL V       LG    GV++S+ AD+           GD   +++FK M GK  I  ++DP           K  L PTPK + H+ +         +   I SL+          + YE+    L    RPRH CP A + F YK
Sbjct:  101 QIPRKSREKKALFQPLTPGSREFEDVVNILHSSYLEPTSVTNFNYRRACLVHNELLEKEFTEKRRELKFDGRLDKELSESYAFLM-VDRYQVQTICEKGLHVGQSKITILGSPSMGVYLSRYADLLQANPLDTGAMGD---VVIFKIMKGK--IKSIYDPMGVKSLESMLNKSALDPTPKHECHVSK---------NANRITSLLAYRAYELTQYYFYEYGFDELRR--RPRHVCPYAVVSFTYK 328
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Human
Match: TASOR (transcription activation suppressor [Source:HGNC Symbol;Acc:HGNC:30314])

HSP 1 Score: 52.373 bits (124), Expect = 3.497e-6
Identity = 68/245 (27.76%), Postives = 103/245 (42.04%), Query Frame = 1 
Query:  148 EVPGNSRETYDMFQKL---SKTFVD--NSFDFS-------QSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDP-----------KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLV----------FLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            ++P  SRE   +FQ L   S+ F D  N    S        +++ ++A ++ N L E+EF EK +EL+      +     Y FL  +    +  +   GL V       LG    GV++S+ AD+           GD   +++FK M GK  I  ++DP           K  L PTPK + H+ +         +   I SL+          + YE+    L    RPRH CP A + F YK
Sbjct:  101 QIPRKSREKKALFQPLTPGSREFEDVVNILHSSYLEPTSVTNFNYRRACLVHNELLEKEFTEKRRELKFDGRLDKELSESYAFL-MVDRYQVQTICEKGLHVGQSKITILGSPSMGVYLSRYADLLQANPLDTGAMGD---VVIFKIMKGK--IKSIYDPMGVKSLESMLNKSALDPTPKHECHVSK---------NANRITSLLAYRAYELTQYYFYEYGFDELRR--RPRHVCPYAVVSFTYK 328
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Zebrafish
Match: BX649301.2 (transcription activation suppressor b [Source:NCBI gene;Acc:566775])

HSP 1 Score: 67.0106 bits (162), Expect = 7.746e-11
Identity = 70/212 (33.02%), Postives = 105/212 (49.53%), Query Frame = 1 
Query:  151 VPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQ-YIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            +P  SRE  D+ + LS  ++D +     +++  KA +I N L E+EF EK +EL++           Y FL   + K +  +   GL V     N LG +  GV++S+ +D+          AG+   +ILFK M GK KI+  + PK  L PT KFDSH+ +         S + +  +  + YEFA   L    RPRH  P A + F+YK
Sbjct:  109 LPPESREFEDVVKLLSTFYLDATS--RATFNYTKASLIHNELLEKEFIEKKRELKQNGRTEAELAESYAFLLPDRNK-VHFICEKGLSVGHSRINNLGNSAKGVYLSKYSDLLQMNPFEVGAAGE---IILFKVMKGKVKII-ENIPKNTLEPTLKFDSHVYKNASKVTSLLSYRAFEHTQQYFYEFAYDELKS--RPRHVLPYAVVSFQYK 311
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Zebrafish
Match: tasorb (transcription activation suppressor b [Source:ZFIN;Acc:ZDB-GENE-090311-29])

HSP 1 Score: 66.6254 bits (161), Expect = 9.998e-11
Identity = 69/212 (32.55%), Postives = 106/212 (50.00%), Query Frame = 1 
Query:  151 VPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQ-YIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            +P  SRE  D+ + LS  ++D +     +++  KA +I N L E+EF EK +EL++           Y FL + + K +  +   GL V     N LG +  GV++S+ +D+          AG+   +ILFK M GK KI+  + PK  L PT K+DSH+ +         S + +  +  + YEFA   L    RPRH  P A + F+YK
Sbjct:  109 LPPESREFEDVVKLLSTFYLDATS--RATFNYTKASLIHNELLEKEFIEKKRELKQNGRTEAELAESYAFLLSDRNK-VHFICEKGLSVGHSRINNLGNSAKGVYLSKYSDLLQMNPFEVGAAGE---IILFKVMKGKVKII-ENIPKNTLEPTLKYDSHVYKNASKVTSLLSYRAFEHTQQYFYEFAYDELKS--RPRHVLPYAVVSFQYK 311
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Zebrafish
Match: tasorb (transcription activation suppressor b [Source:ZFIN;Acc:ZDB-GENE-090311-29])

HSP 1 Score: 66.6254 bits (161), Expect = 9.998e-11
Identity = 69/212 (32.55%), Postives = 106/212 (50.00%), Query Frame = 1 
Query:  151 VPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQ-YIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            +P  SRE  D+ + LS  ++D +     +++  KA +I N L E+EF EK +EL++           Y FL + + K +  +   GL V     N LG +  GV++S+ +D+          AG+   +ILFK M GK KI+  + PK  L PT K+DSH+ +         S + +  +  + YEFA   L    RPRH  P A + F+YK
Sbjct:  109 LPPESREFEDVVKLLSTFYLDATS--RATFNYTKASLIHNELLEKEFIEKKRELKQNGRTEAELAESYAFLLSDRNK-VHFICEKGLSVGHSRINNLGNSAKGVYLSKYSDLLQMNPFEVGAAGE---IILFKVMKGKVKII-ENIPKNTLEPTLKYDSHVYKNASKVTSLLSYRAFEHTQQYFYEFAYDELKS--RPRHVLPYAVVSFQYK 311
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Zebrafish
Match: tasor2 (transcription activation suppressor family member 2 [Source:ZFIN;Acc:ZDB-GENE-041111-225])

HSP 1 Score: 59.3066 bits (142), Expect = 1.768e-8
Identity = 45/148 (30.41%), Postives = 65/148 (43.92%), Query Frame = 1 
Query:  352 YGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDS--IQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPM 789
            +GFL         KV   GL V     + LG ++ GV+IS+ +D CL   R     G    ++L K   GK K V  +  +    PTP FD H+ E+        S  + + ++  + YE   G+      PRH CP A + F Y  M
Sbjct:   82 FGFLLLDDINRARKVGETGLLVGRAKCSTLGDSLKGVYISKYSD-CLDLKR--WYDGKTGYIVLLKLTKGKVKEVKDNYTQNFTPPTPGFDCHVSEQLGAVSSTTSSFLAFERTQYYFYEICKGSSKTEACPRHACPFAIVAFSYGKM 226
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Zebrafish
Match: tasor2 (transcription activation suppressor family member 2 [Source:ZFIN;Acc:ZDB-GENE-041111-225])

HSP 1 Score: 59.3066 bits (142), Expect = 1.875e-8
Identity = 45/148 (30.41%), Postives = 65/148 (43.92%), Query Frame = 1 
Query:  352 YGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDS--IQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPM 789
            +GFL         KV   GL V     + LG ++ GV+IS+ +D CL   R     G    ++L K   GK K V  +  +    PTP FD H+ E+        S  + + ++  + YE   G+      PRH CP A + F Y  M
Sbjct:   82 FGFLLLDDINRARKVGETGLLVGRAKCSTLGDSLKGVYISKYSD-CLDLKR--WYDGKTGYIVLLKLTKGKVKEVKDNYTQNFTPPTPGFDCHVSEQLGAVSSTTSSFLAFERTQYYFYEICKGSSKTEACPRHACPFAIVAFSYGKM 226
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Mouse
Match: Tex15 (testis expressed gene 15 [Source:MGI Symbol;Acc:MGI:1934816])

HSP 1 Score: 83.5741 bits (205), Expect = 5.989e-17
Identity = 65/215 (30.23%), Postives = 109/215 (50.70%), Query Frame = 1 
Query:  139 YISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGK-RKIVPMHDP-KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFK 777
            Y+S    N+RE   +   L +  +D S D   +W   +  ++ N   E++F  K  E+ E   +S   +  + FLA  +  ++D V  +GL V   P   LG  + GV++ ++ D+ L+ A  + VA + +  ++FK + G+ +KI P  D  KV L P+P FD H+    P  K+   +Q   S+V+ YE+   +  PV +PR C P A +  K
Sbjct:   48 YLSSCYTNTREYGFIHGTLKQCRLDMSCDLQFTWQFGETKLVRNEYLEKQFAAKRSEMREGGRHSRELEEHFCFLALPQADVMD-VYQNGLSVGTSPLRILGNPLLGVYLCRHVDIALSHACSRSVAVESI--MIFKVLFGRIKKIQPSMDKNKVSLDPSPNFDCHMSRNMPSLKDTIELQAYNSMVYFYEYDYFS-RPVDKPRQCLPYAIVTVK 258
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Mouse
Match: Tex15 (testis expressed gene 15 [Source:MGI Symbol;Acc:MGI:1934816])

HSP 1 Score: 82.4185 bits (202), Expect = 1.617e-15
Identity = 65/215 (30.23%), Postives = 109/215 (50.70%), Query Frame = 1 
Query:  139 YISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGK-RKIVPMHDP-KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFK 777
            Y+S    N+RE   +   L +  +D S D   +W   +  ++ N   E++F  K  E+ E   +S   +  + FLA  +  ++D V  +GL V   P   LG  + GV++ ++ D+ L+ A  + VA + +  ++FK + G+ +KI P  D  KV L P+P FD H+    P  K+   +Q   S+V+ YE+   +  PV +PR C P A +  K
Sbjct:   48 YLSSCYTNTREYGFIHGTLKQCRLDMSCDLQFTWQFGETKLVRNEYLEKQFAAKRSEMREGGRHSRELEEHFCFLALPQADVMD-VYQNGLSVGTSPLRILGNPLLGVYLCRHVDIALSHACSRSVAVESI--MIFKVLFGRIKKIQPSMDKNKVSLDPSPNFDCHMSRNMPSLKDTIELQAYNSMVYFYEYDYFSR-PVDKPRQCLPYAIVTVK 258
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Mouse
Match: Tasor (transcription activation suppressor [Source:MGI Symbol;Acc:MGI:1921694])

HSP 1 Score: 51.9878 bits (123), Expect = 3.698e-6
Identity = 65/236 (27.54%), Postives = 99/236 (41.95%), Query Frame = 1 
Query:  148 EVPGNSRETYDMFQKL---SKTFVDNSFDFSQSW---------DLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDP-----------KVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIR-PRHCCPSAAMIFKYK 783
            ++P  SRE   +FQ L   S+ F D       S+         + ++A +I N L E+EF EK +EL+      +     Y FL  +    +  +   GL+V       LG    G+++ + AD+           GD   +++FK M GK  I  ++DP           K  L PTPK + H+   +   +    + Y    +  Y F     D V R PRH CP A + F YK
Sbjct:   96 QIPRKSREKKALFQPLTPGSREFEDVLNILHSSYLEPSSVTYFNYRRACLIHNELLEKEFTEKRRELKFDGRLDKELSESYAFLM-VDRYQVQSICEKGLQVGQSKITVLGSPSMGIYLCRYADLLQANPLEAGAVGD---VVIFKIMKGK--IKSIYDPLSVKSLESMLSKNALDPTPKHECHV--SKNASRITSLLAYRAYELTQYYFYEYGFDEVRRRPRHVCPYAVVSFTYK 323
[Close]
BLAST of DUF3715 domain-containing protein vs. TrEMBL
Match: A0A1I8HB87 (DUF3715 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 6.342e-30
Identity = 75/206 (36.41%), Postives = 118/206 (57.28%), Query Frame = 1 
Query:  178 DMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIV-AGDELVLILFKYMLGK-RKIVPMHDPK--VLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
             +F+    +F++        W L K  ++ N  FE EF E+  E   +    +     YGFLA   E+++D    +GL+V+ CP N LGY ++GVH+  + DVCL EA  +    G+++VL+ FK+M G+ R++ P+  PK   ++AP+P F+ HI + RP   ++ S QY++SL +LYEF N    PV RPR C P AA+  + +
Sbjct:   23 QIFRGFVDSFLNPPSATLDQWRLVKLEMLENGYFEEEFSERRAEFSRQGLAQDELSTHYGFLAAASEELVDLTLREGLKVRFCPINSLGYCISGVHLCVHGDVCLQEAALETGDDGEQIVLVAFKFMFGRTRRVTPV-TPKDMAIIAPSPGFNCHIPDVRPGRTDSLSDQYLRSLAYLYEFENSFYHPVPRPRQCSPLAALYLRRR 227
[Close]
BLAST of DUF3715 domain-containing protein vs. TrEMBL
Match: A0A1I8H7Z4 (DUF3715 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 6.381e-30
Identity = 75/206 (36.41%), Postives = 118/206 (57.28%), Query Frame = 1 
Query:  178 DMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIV-AGDELVLILFKYMLGK-RKIVPMHDPK--VLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
             +F+    +F++        W L K  ++ N  FE EF E+  E   +    +     YGFLA   E+++D    +GL+V+ CP N LGY ++GVH+  + DVCL EA  +    G+++VL+ FK+M G+ R++ P+  PK   ++AP+P F+ HI + RP   ++ S QY++SL +LYEF N    PV RPR C P AA+  + +
Sbjct:   23 QIFRGFVDSFLNPPSATLDQWRLVKLEMLENGYFEEEFSERRAEFSRQGLAQDELSTHYGFLAAASEELVDLTLREGLKVRFCPINSLGYCISGVHLCVHGDVCLQEAALETGDDGEQIVLVAFKFMFGRTRRVTPV-TPKDMAIIAPSPGFNCHIPDVRPGRTDSLSDQYLRSLAYLYEFENSFYHPVPRPRQCSPLAALYLRRR 227
[Close]
BLAST of DUF3715 domain-containing protein vs. TrEMBL
Match: A0A267GDX0 (DUF3715 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000758g2 PE=4 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 5.754e-29
Identity = 75/206 (36.41%), Postives = 118/206 (57.28%), Query Frame = 1 
Query:  178 DMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIV-AGDELVLILFKYMLGK-RKIVPMHDPK--VLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
             +F+    +F++        W L K  ++ N  FE EF E+  E   +    +     YGFLA   E+++D    +GL+V+ CP N LGY ++GVH+  + DVCL EA  +    G+++VL+ FK+M G+ R++ P+  PK   ++AP+P F+ HI + RP   ++ S QY++SL +LYEF N    PV RPR C P AA+  + +
Sbjct:   23 QIFRGFVDSFLNPPSATLDQWRLVKLEMLENGYFEEEFSERRAEFSRQGLAQDELSTHYGFLAAASEELVDLTLREGLKVRFCPINSLGYCISGVHLCVHGDVCLQEAALETGDDGEQIVLVAFKFMFGRTRRVTPV-TPKDMAIIAPSPGFNCHIPDVRPGRTDSLSDQYLRSLAYLYEFENSFYHPVPRPRQCSPLAALYLRRR 227
[Close]
BLAST of DUF3715 domain-containing protein vs. TrEMBL
Match: A0A267ESJ1 (DUF3715 domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032307g1 PE=4 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 7.017e-29
Identity = 75/206 (36.41%), Postives = 118/206 (57.28%), Query Frame = 1 
Query:  178 DMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIV-AGDELVLILFKYMLGK-RKIVPMHDPK--VLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
             +F+    +F++        W L K  ++ N  FE EF E+  E   +    +     YGFLA   E+++D    +GL+V+ CP N LGY ++GVH+  + DVCL EA  +    G+++VL+ FK+M G+ R++ P+  PK   ++AP+P F+ HI + RP   ++ S QY++SL +LYEF N    PV RPR C P AA+  + +
Sbjct:   35 QIFRGFVDSFLNPPSATLDQWRLVKLEMLENGYFEEEFSERRAEFSRQGLAQDELSTHYGFLAAASEELVDLTLREGLKVRFCPINSLGYCISGVHLCVHGDVCLQEAALETGDDGEQIVLVAFKFMFGRTRRVTPV-TPKDMAIIAPSPGFNCHIPDVRPGRTDSLSDQYLRSLAYLYEFENSFYHPVPRPRQCSPLAALYLRRR 239
[Close]
BLAST of DUF3715 domain-containing protein vs. TrEMBL
Match: A0A1I8FKM2 (DUF3715 domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 6.786e-25
Identity = 56/132 (42.42%), Postives = 87/132 (65.91%), Query Frame = 1 
Query:  352 YGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIV-AGDELVLILFKYMLGK-RKIVPMHDPK--VLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVI 735
            YGFLA   E+++D    +GL+V+ CP N LGY ++GVH+  + DVCL EA  +    G+++VL+ FK+M G+ R++ P+  PK   ++AP+P F+ HI + RP   ++ S QY++SL +LYEF N    PV+
Sbjct:   36 YGFLAAASEELVDLTLREGLKVRFCPINSLGYCISGVHLCVHGDVCLQEAALETGDDGEQIVLVAFKFMFGRTRRVTPV-TPKDMAIIAPSPGFNCHIPDVRPGRTDSLSDQYLRSLAYLYEFENSFYHPVV 166
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Cavefish
Match: tasorb (protein TASOR-like [Source:NCBI gene;Acc:103032451])

HSP 1 Score: 63.1586 bits (152), Expect = 9.230e-10
Identity = 67/218 (30.73%), Postives = 102/218 (46.79%), Query Frame = 1 
Query:  151 VPGNSRETYDMFQKLSKTFVD----NSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIK---SLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            +P +SRE  ++ + LS  ++D     +F ++      KA +I N L E+EF EK +EL++           Y FL     K    +   GL V     + LG    GV++S+ +D+          +GD   +I+FK M G+ K +  + PK  L P PKFD H+   +   K    + Y     +  + YEFA   L    RPRH CP A + F+YK
Sbjct:  113 LPPDSREFEELVKVLSSFYLDAPSRGAFTYT------KACLIHNELLEKEFVEKKRELKQAGRTEAELTESYAFLLPDTNK-THWICEKGLSVGHARLSNLGNPAKGVYLSKYSDLLQINPFDAGASGD---IIIFKVMKGRLKSIFENMPKSNLEPAPKFDCHV--HKNASKVTSLLSYRAFELTQQYFYEFAFDELK--SRPRHVCPYAVVSFQYK 316
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000047323.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:23486567:23497796:1 gene:ENSAMXG00000010014.2 transcript:ENSAMXT00000047323.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.2326 bits (147), Expect = 4.397e-9
Identity = 45/143 (31.47%), Postives = 66/143 (46.15%), Query Frame = 1 
Query:  349 RYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGK-RKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIF 774
            RY +L    E       H GL  +      LG    GV++ ++ DV L  A    +    L  I+FK + GK +K+ P  D      P   FD H+ +E    +E+ S Q + S VFL+++ N N +   RPR C P A + F
Sbjct:   14 RYCYLVASHETTTQIYRH-GLRTETQQQYSLGKPSHGVYLFRHVDVALKHAASSSLTAKNL--IVFKVLFGKVKKVTPTSDWNRTPDPMVTFDCHMSKEAVSHRESLSQQVLGSSVFLFDY-NDNQELNSRPRQCLPYAVVSF 152
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000010285.2 (pep primary_assembly:Astyanax_mexicanus-2.0:20:23449006:23497796:1 gene:ENSAMXG00000010014.2 transcript:ENSAMXT00000010285.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 5.247e-9
Identity = 45/143 (31.47%), Postives = 66/143 (46.15%), Query Frame = 1 
Query:  349 RYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGK-RKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIF 774
            RY +L    E       H GL  +      LG    GV++ ++ DV L  A    +    L  I+FK + GK +K+ P  D      P   FD H+ +E    +E+ S Q + S VFL+++ N N +   RPR C P A + F
Sbjct:   46 RYCYLVASHETTTQIYRH-GLRTETQQQYSLGKPSHGVYLFRHVDVALKHAASSSLTAKNL--IVFKVLFGKVKKVTPTSDWNRTPDPMVTFDCHMSKEAVSHRESLSQQVLGSSVFLFDY-NDNQELNSRPRQCLPYAVVSF 184
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Cavefish
Match: tasor2 (transcription activation suppressor family member 2 [Source:ZFIN;Acc:ZDB-GENE-041111-225])

HSP 1 Score: 55.4546 bits (132), Expect = 2.200e-7
Identity = 42/145 (28.97%), Postives = 67/145 (46.21%), Query Frame = 1 
Query:  352 YGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDS--IQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKY 780
            +GFL   ++   + +A +GL V       LG +  GV+IS+ +D CL   R     G    ++L K   G+ K V  +  +    PT  FD H+ ++        S  + + ++  +LYE  +G   P   PRH CP A + F Y
Sbjct:   74 FGFLLFDEKSRANTLADNGLMVGQGTCTILGDSSKGVYISKYSD-CLDLKR--WYDGKTGYIVLLKLTKGRVKEVTENYTQNFTPPTAGFDCHVSDQLGAVCATTSSFLAFERTQYYLYELLDGGNKPEPCPRHVCPFAVVAFSY 215
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007451.1 (pep scaffold:Pmarinus_7.0:GL479998:21484:29457:1 gene:ENSPMAG00000006728.1 transcript:ENSPMAT00000007451.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 5.269e-7
Identity = 48/173 (27.75%), Postives = 73/173 (42.20%), Query Frame = 1 
Query:  343 DVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVL------------LAPTPKFDSHICEERP---DPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYK------PMYDK 798
            D  YGF     E+   +   +GL V       LG    GV++   +DV L   +  I  G   V+++FK +  K +I  +H   +L              P+ +FD H+ ++         ND   +  S  +L+EF  G LD   RPR  CP A + F Y+      P+ DK
Sbjct:   20 DESYGFFLADSERSAKEACQNGLCVGNVKTGCLGTPKMGVYLCSFSDV-LQPMQLPIGTG---VMLIFK-ICKKIQIKNIHFKSLLDQLSFEQFFTFSFNPSSQFDCHVSKKLAFVNSSSNNDCFVHKHSQCYLFEF--GELDICRRPRQVCPYAMVAFSYEGDGISVPLRDK 185
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Nematostella
Match: EDO37875 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEJ9])

HSP 1 Score: 50.8322 bits (120), Expect = 2.101e-6
Identity = 48/174 (27.59%), Postives = 75/174 (43.10%), Query Frame = 1 
Query:  343 DVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDP---KVLLAPTPKFDSHICEERPD--PKENDSIQYIKSLVFLYEFANGNLD-PVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEENKFSVTYP 846
            D +  FL       +  +  +GL         LG    GV+  + ADV     +    AGDE  L++FK   GK K V    P   + LL PTP +D H+ +   +  P+   S  Y  +  + +EF     D  V RPRH  P A +     P+ ++  +I  ++ K ++  P
Sbjct:  148 DDKLAFLFKSSRTEVKDICENGLATGSSKTVTLGDPSMGVYACRYADVV---QKRPFQAGDEGYLLVFKVCKGKVKPV-FETPCGSETLLEPTPNYDCHVSKTMHNLPPQPPFSSLYYSTQYYFFEFDEEGADFHVKRPRHVLPYAVLTLSV-PVIEEPKLIPQQKTKKALKGP 316
[Close]
BLAST of DUF3715 domain-containing protein vs. Ensembl Medaka
Match: tasorb (protein TASOR [Source:NCBI gene;Acc:101164979])

HSP 1 Score: 64.3142 bits (155), Expect = 4.024e-10
Identity = 68/221 (30.77%), Postives = 105/221 (47.51%), Query Frame = 1 
Query:  151 VPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLV----------FLYEFANGNLDPVIRPRHCCPSAAMIFKYK 783
            +P +SRE  D+ + +S   +D S   + S+   KA +I N L E+EF EK +E++++    +     Y FL   K K+   V   GL V  C    LG    GV++S+ +D+           GD   +I+FK M G+ K +  + PK  + P+PKFD H+         +     + SL+          F +EFA   +    RPRH CP A + F+YK
Sbjct:  107 LPPDSREFEDLIKLISSFNLDPSSRTAFSYS--KARLIHNELLEKEFIEKRREMKQEGRTEQDLAESYCFLFPDKSKL-QWVCEKGLSVGHCRITTLGNPSMGVYLSKYSDLLQINPFEVGSFGD---MIIFKIMRGRIKHIHENMPKNAIEPSPKFDCHL---------SKIANRVTSLLSYRAFELTQQFFFEFAFDEIK--ARPRHVCPYAVVSFQYK 310
[Close]
BLAST of DUF3715 domain-containing protein vs. Planmine SMEST
Match: SMESG000032087.1 (SMESG000032087.1)

HSP 1 Score: 772.696 bits (1994), Expect = 0.000e+0
Identity = 392/394 (99.49%), Postives = 393/394 (99.75%), Query Frame = 1 
Query:  100 MHSSNSVLDSNAYYISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEENKFSVTYPSPLALLKPVSQHAPVSFWDRQYSDYKKSSTQNLDAEDSRKVIATEINKELYDIEKPTTVDDTWKTINYGPAYPNDGGYRDMYSSNPKGISRNGGESMLLKPMERERSTERNKKWSESSSRGASKSNRGSDSSRRASFRGSKAWFK 1281
            MHSSNSVLDSNAYYISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFEREFKEKSKELEEKSSYSEHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIV+GDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEENKFSVTYPSPLALLKPVSQHAPVSFWDRQYSDYKKSSTQNLDAEDSRKVIATEINKELYDIEKPTTVDDTWKTINYGPAYPNDGGYRDMYSSNPKGISRNGGESMLLKPMERERSTERNKKWSESSSRG SKSNRGSDSSRRASFRGSKAWFK
Sbjct:    1 MHSSNSVLDSNAYYISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFEREFKEKSKELEEKSSYSEHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVSGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEENKFSVTYPSPLALLKPVSQHAPVSFWDRQYSDYKKSSTQNLDAEDSRKVIATEINKELYDIEKPTTVDDTWKTINYGPAYPNDGGYRDMYSSNPKGISRNGGESMLLKPMERERSTERNKKWSESSSRGVSKSNRGSDSSRRASFRGSKAWFK 394
[Close]
BLAST of DUF3715 domain-containing protein vs. Planmine SMEST
Match: SMESG000032082.1 (SMESG000032082.1)

HSP 1 Score: 259.61 bits (662), Expect = 2.368e-79
Identity = 160/374 (42.78%), Postives = 226/374 (60.43%), Query Frame = 1 
Query:  139 YISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEE--------NKFSVTYPSPLALLKPVSQHAPVSFWDRQYSDYKKSS--TQNLDAEDSRKVIATEINKELYDIEKPTTVDDTWKTINYGPAYPNDGGYRDMYSSNPKGISRNGGESMLLKPMERERSTERNKKWSESSSRGASKSNRG 1230
            ++ E+   S ETY++ + +S T +++S     SW+L+ A +I N  FEREF EK  E+ E++ YS++WDVR+GFLAT    +IDK+A +GLE+KM PYNYLG+  +GVHIS NADVCL EAR K    +E+ LI+FKYMLGKRK+VPM+DPKVLLAPTP FDSH+CEERP P E  +IQYIKSLV+LYEF++   DPVIRP+HC P  A+IF+     + LD+   E         N F     +P  L KP    A   F      ++K+++  +QN   + S+   +T   +++ D E+       W+ INYG  +                 +++ GES++LKP  RER  +R   W ++ +   +K   G
Sbjct:   20 HVDEIQIESNETYELIENISSTNLNHSVHIEDSWNLKNAFIIQNKSFEREFNEKRDEIRERAYYSDNWDVRFGFLATNNNGLIDKLAEEGLEIKMRPYNYLGHCTSGVHISMNADVCLNEARNKF-NSEEITLIVFKYMLGKRKMVPMYDPKVLLAPTPNFDSHVCEERPIPNEKHAIQYIKSLVYLYEFSDEIYDPVIRPKHCVPIGALIFESLAPSEILDLTESESLDTPFHAINSFMSNSKNP-RLPKPPWSEAYSKF--NNEGNFKRAAIYSQNKSIKQSKN--STNFLQKISDSEQ-------WRPINYGDVF-----------------NQSVGESLILKPQGRERLVDRVGMWKDNKAERTNKWKTG 363
[Close]
BLAST of DUF3715 domain-containing protein vs. Planmine SMEST
Match: SMESG000032082.1 (SMESG000032082.1)

HSP 1 Score: 257.299 bits (656), Expect = 8.578e-79
Identity = 156/369 (42.28%), Postives = 219/369 (59.35%), Query Frame = 1 
Query:  139 YISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQKALVITNPLFXXXXXXXXXXXXXXXXXXXHWDVRYGFLATIKEKMIDKVAHDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFKYMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFLYEFANGNLDPVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEENKFSVTYPSPLALLKPVSQHA-----PVSFWDRQYSDYKKSSTQNLDAEDSRKVIATEINKELYDIEKPTTVDDTWKTINYGPAYPNDGGYRDMYSSNPKGISRNGGESMLLKPMERERSTERNKKWSESSSRGASKSNRG 1230
            ++ E+   S ETY++ + +S T +++S     SW+L+ A +I N  FEREF EK  E+ E++ YS++WDVR+GFLAT    +IDK+A +GLE+KM PYNYLG+  +GVHIS NADVCL EAR K    +E+ LI+FKYMLGKRK+VPM+DPKVLLAPTP FDSH+CEERP P E  +IQYIKSLV+LYEF++   DPVIRP+HC P  A+IF+     + LD+   E      +  +P   +     ++     P   W   YS +        + EDS     T   +++ D E+       W+ INYG  +                 +++ GES++LKP  RER  +R   W ++ +   +K   G
Sbjct:   20 HVDEIQIESNETYELIENISSTNLNHSVHIEDSWNLKNAFIIQNKSFEREFNEKRDEIRERAYYSDNWDVRFGFLATNNNGLIDKLAEEGLEIKMRPYNYLGHCTSGVHISMNADVCLNEARNKF-NSEEITLIVFKYMLGKRKMVPMYDPKVLLAPTPNFDSHVCEERPIPNEKHAIQYIKSLVYLYEFSDEIYDPVIRPKHCVPIGALIFESLAPSEILDLTESE------SLDTPFHAINSFMSNSKNPRLPKPPWSEAYSKF--------NNEDS-----TNFLQKISDSEQ-------WRPINYGDVF-----------------NQSVGESLILKPQGRERLVDRVGMWKDNKAERTNKWKTG 344
The following BLAST results are available for this feature:
BLAST of DUF3715 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
TEX152.493e-1225.93testis expressed 15, meiosis and synapsis associat... [more]
TEX152.579e-1225.93testis expressed 15, meiosis and synapsis associat... [more]
TASOR2.878e-627.76transcription activation suppressor [Source:HGNC S... [more]
TASOR3.497e-627.76transcription activation suppressor [Source:HGNC S... [more]
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BLAST of DUF3715 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF3715 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF3715 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BX649301.27.746e-1133.02transcription activation suppressor b [Source:NCBI... [more]
tasorb9.998e-1132.55transcription activation suppressor b [Source:ZFIN... [more]
tasorb9.998e-1132.55transcription activation suppressor b [Source:ZFIN... [more]
tasor21.768e-830.41transcription activation suppressor family member ... [more]
tasor21.875e-830.41transcription activation suppressor family member ... [more]
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BLAST of DUF3715 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF3715 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Tex155.989e-1730.23testis expressed gene 15 [Source:MGI Symbol;Acc:MG... [more]
Tex151.617e-1530.23testis expressed gene 15 [Source:MGI Symbol;Acc:MG... [more]
Tasor3.698e-627.54transcription activation suppressor [Source:MGI Sy... [more]
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BLAST of DUF3715 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF3715 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HB876.342e-3036.41DUF3715 domain-containing protein OS=Macrostomum l... [more]
A0A1I8H7Z46.381e-3036.41DUF3715 domain-containing protein OS=Macrostomum l... [more]
A0A267GDX05.754e-2936.41DUF3715 domain-containing protein OS=Macrostomum l... [more]
A0A267ESJ17.017e-2936.41DUF3715 domain-containing protein (Fragment) OS=Ma... [more]
A0A1I8FKM26.786e-2542.42DUF3715 domain-containing protein OS=Macrostomum l... [more]
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BLAST of DUF3715 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
tasorb9.230e-1030.73protein TASOR-like [Source:NCBI gene;Acc:103032451... [more]
ENSAMXT00000047323.14.397e-931.47pep primary_assembly:Astyanax_mexicanus-2.0:20:234... [more]
ENSAMXT00000010285.25.247e-931.47pep primary_assembly:Astyanax_mexicanus-2.0:20:234... [more]
tasor22.200e-728.97transcription activation suppressor family member ... [more]
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BLAST of DUF3715 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000007451.15.269e-727.75pep scaffold:Pmarinus_7.0:GL479998:21484:29457:1 g... [more]
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BLAST of DUF3715 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF3715 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO378752.101e-627.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DUF3715 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
tasorb4.024e-1030.77protein TASOR [Source:NCBI gene;Acc:101164979][more]
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BLAST of DUF3715 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000032087.10.000e+099.49SMESG000032087.1[more]
SMESG000032082.12.368e-7942.78SMESG000032082.1[more]
SMESG000032082.18.578e-7942.28SMESG000032082.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30012104 ID=SMED30012104|Name=DUF3715 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2228bp
TTCTCTTCCATTTATTTGCTCTCTTTGTGTATACTTTTGTTTTAAATTTT
AAGAAAAATATTTAAATCATCATACAATTTCTATATATAACAGTTAAAAA
TGCACTCGTCAAACTCAGTTTTAGATTCAAATGCATATTATATCAGCGAA
GTTCCTGGAAATAGTCGGGAAACTTACGATATGTTTCAAAAACTCTCAAA
GACGTTTGTGGATAATTCTTTTGATTTTTCACAATCTTGGGATTTGCAAA
AAGCTTTAGTTATCACAAATCCATTATTTGAACGCGAATTTAAAGAGAAA
AGCAAAGAATTGGAAGAGAAATCCTCGTATTCCGAACATTGGGACGTTAG
ATATGGTTTTCTTGCAACAATTAAAGAAAAAATGATTGACAAAGTTGCTC
ACGACGGCTTAGAAGTTAAAATGTGTCCTTATAATTATTTGGGATACAAT
GTTGCGGGTGTGCATATTAGTCAAAATGCAGACGTGTGTTTAACAGAAGC
ACGAGGTAAAATTGTGGCAGGCGATGAATTAGTACTTATTTTATTCAAGT
ACATGCTTGGTAAAAGAAAGATTGTTCCCATGCATGATCCAAAAGTTCTT
CTAGCGCCTACTCCAAAATTTGACTCTCATATATGTGAAGAAAGACCAGA
TCCAAAAGAAAATGATTCTATTCAATATATTAAATCTCTGGTCTTTCTCT
ATGAGTTTGCCAATGGAAATTTGGATCCTGTAATTCGTCCGAGACATTGC
TGCCCTTCGGCTGCAATGATTTTTAAATATAAACCGATGTATGACAAATT
AGATGTAATTGGCGTAGAAGAAAACAAGTTTTCTGTGACCTATCCAAGCC
CATTAGCATTATTAAAACCAGTATCCCAACATGCACCGGTTTCATTTTGG
GATCGTCAATATTCAGATTACAAAAAATCTTCAACTCAAAATCTAGACGC
GGAAGATTCTCGAAAGGTAATTGCAACTGAAATAAATAAAGAACTATATG
ATATTGAAAAGCCGACAACAGTTGATGATACATGGAAAACCATTAATTAT
GGTCCAGCTTATCCGAACGATGGAGGGTATCGAGATATGTACAGCAGCAA
TCCCAAAGGAATATCGAGAAATGGAGGTGAATCGATGCTCCTAAAACCAA
TGGAAAGGGAACGAAGTACAGAAAGAAATAAAAAGTGGTCTGAATCTTCA
TCGCGCGGAGCCAGTAAAAGTAATAGGGGCTCTGACTCGTCTAGAAGAGC
ATCATTTAGAGGCTCTAAAGCATGGTTCAAATAATTTGCTTTATTCTTTT
GTTGTATTCTATATTGTTGTTATTAAATATCTTATCGTTTTTACTCTGCC
CAACAAATATAATGTCTAGTGACTTTTTAATCTATTATTTGGATTTTAAG
GTCATTGAAATTAGTTTTTAAAACTTGTTAATTTATGTATTTCTGTTTGG
TAATTTTCTTTTAAAATTGATTTCACCAATATTTTTTGTTAATTACAAAG
GAGTGGAGTTTTAAGAATAAATGAAGCCTAAATTAATAAAATATTTATCA
TGGTTTTTCGGTTGAGACCAGGCTGAAAGTTCACACGGCACCGATGAGAG
CTCGAAACTAGTTTGAAATTAGAATTCACATAATTTTTTAAAAATTTATT
CGTTAATTGATGAAGTTTGGAAAATACTCATCCGGAAACAAGTGTTTTGC
AAACCAGTTTTTGTTACTTGTACAAAATTTTATTTACAATTTAAAATTTG
CTGTACTTTCTATTATAACCGAAACTGATATCGTCTTTTATTCAAAATTA
ATTTTAGTATTGTTTTTCAAAATTTTGTTGGTGCTAATCTATTATTTGTA
TTCATTTATACAAGAGAAATTACTAAGTTTTCGTCAAAATTTTGCCATAT
TACCTCTAACTTTTGATTATTGTTGCACGGTTTGTCTTATTTTATTGTAA
TGTAAAATAAGGAAATCAAACTAAGTAACTTGAACTATTCAAGTGACCAA
ACTGTATATCTCTGATTCAATTGGGATTTTCCAAAGGTTAATCTGCATTT
CTTTAAAATTTTCGTCTAAAACCTATCAAGGCATTACTCAAAAGTTGTCA
CCAACCCTAAACAATATGTTCTTATTAACATTAATTATTTTATTTATTTA
TTGTAAATTTGTGTGTTCTGCGGTGTACAACCAAATCTGCTGCGGAGGCA
AGCACCCTACATAATGCCAAATCCCAAT
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protein sequence of SMED30012104-orf-1

>SMED30012104-orf-1 ID=SMED30012104-orf-1|Name=SMED30012104-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=395bp
MHSSNSVLDSNAYYISEVPGNSRETYDMFQKLSKTFVDNSFDFSQSWDLQ
KALVITNPLFEREFKEKSKELEEKSSYSEHWDVRYGFLATIKEKMIDKVA
HDGLEVKMCPYNYLGYNVAGVHISQNADVCLTEARGKIVAGDELVLILFK
YMLGKRKIVPMHDPKVLLAPTPKFDSHICEERPDPKENDSIQYIKSLVFL
YEFANGNLDPVIRPRHCCPSAAMIFKYKPMYDKLDVIGVEENKFSVTYPS
PLALLKPVSQHAPVSFWDRQYSDYKKSSTQNLDAEDSRKVIATEINKELY
DIEKPTTVDDTWKTINYGPAYPNDGGYRDMYSSNPKGISRNGGESMLLKP
MERERSTERNKKWSESSSRGASKSNRGSDSSRRASFRGSKAWFK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000136whole organism
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR026616TEX15
IPR022188DUF3715
Vocabulary: molecular function
TermDefinition
GO:0003950NAD+ ADP-ribosyltransferase activity
Vocabulary: biological process
TermDefinition
GO:0007129synapsis
GO:0007140male meiotic nuclear division
GO:0010569regulation of double-strand break repair via homologous recombination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR022188Protein of unknown function DUF3715PFAMPF12509DUF3715coord: 84..219
e-value: 1.3E-16
score: 61.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 347..366
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 367..385
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 334..394
IPR026616Testis-expressed sequence 15 proteinPANTHERPTHR22380FAMILY NOT NAMEDcoord: 13..226