slc35c-4

Overview


Name	slc35c-4 (AKN21648.1)
Smed ID	SMED30012061
Length (bp)	601

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of slc35c-4 (SMED30012061) t-SNE clustered cells

Violin plots show distribution of expression levels for slc35c-4 (SMED30012061) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc35c-4 (SMED30012061) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc35c-4 (SMED30012061) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012061

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
parenchyma	SMED30012061	SMESG000017437.1	dd_Smed_v4_14231_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of slc35c-4 vs. Ensembl Human
Match: SLC35C2 (solute carrier family 35 member C2 [Source:HGNC Symbol;Acc:HGNC:17117])

HSP 1 Score: 115.931 bits (289), Expect = 1.273e-30
Identity = 65/147 (44.22%), Postives = 92/147 (62.59%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   L  G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D     ++    SPD
Sbjct:  171 LGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPD 317

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BLAST of slc35c-4 vs. Ensembl Human
Match: SLC35C2 (solute carrier family 35 member C2 [Source:HGNC Symbol;Acc:HGNC:17117])

HSP 1 Score: 116.316 bits (290), Expect = 1.454e-30
Identity = 65/147 (44.22%), Postives = 92/147 (62.59%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   L  G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D     ++    SPD
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPD 338

[Close]

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   L  G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D     ++    SPD
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPD 338

[Close]

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   L  G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D     ++    SPD
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPD 338

[Close]

BLAST of slc35c-4 vs. Ensembl Human
Match: SLC35C2 (solute carrier family 35 member C2 [Source:HGNC Symbol;Acc:HGNC:17117])

HSP 1 Score: 116.316 bits (290), Expect = 2.007e-30
Identity = 65/147 (44.22%), Postives = 92/147 (62.59%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   L  G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D     ++    SPD
Sbjct:  221 LGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPD 367

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BLAST of slc35c-4 vs. Ensembl Celegans
Match: Y47G6A.7 (pep chromosome:WBcel235:I:3502738:3508421:1 gene:WBGene00021637.1 transcript:Y47G6A.7b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y47G6A.7)

HSP 1 Score: 97.8265 bits (242), Expect = 4.962e-24
Identity = 54/138 (39.13%), Postives = 83/138 (60.14%), Query Frame = 3

Query:  105 GLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRI 518
             + HP+DM+ HVQPWM++ ++P+    EG E+  +S  F F    +   +  ++  G +LAF ME +EYL++  TS +TL I GI+KE+  L LA  +NKD +  +N  GL+ CL G+ LH + K       Q++SRI
Sbjct:  255 AVRHPLDMVAHVQPWMMIPIIPMIWLFEGAEINWNS-VFSFKGHYDPWLVMGLIAGGGLLAFCMEMSEYLLLVNTSGITLNIFGIVKEVATLLLAHIVNKDTLTELNICGLVLCLSGMLLHGMNK-----RHQRLSRI 386

[Close]

BLAST of slc35c-4 vs. Ensembl Celegans
Match: Y47G6A.7 (pep chromosome:WBcel235:I:3502738:3508421:1 gene:WBGene00021637.1 transcript:Y47G6A.7b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y47G6A.7)

HSP 1 Score: 97.8265 bits (242), Expect = 4.962e-24
Identity = 54/138 (39.13%), Postives = 83/138 (60.14%), Query Frame = 3

Query:  105 GLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRI 518
             + HP+DM+ HVQPWM++ ++P+    EG E+  +S  F F    +   +  ++  G +LAF ME +EYL++  TS +TL I GI+KE+  L LA  +NKD +  +N  GL+ CL G+ LH + K       Q++SRI
Sbjct:  255 AVRHPLDMVAHVQPWMMIPIIPMIWLFEGAEINWNS-VFSFKGHYDPWLVMGLIAGGGLLAFCMEMSEYLLLVNTSGITLNIFGIVKEVATLLLAHIVNKDTLTELNICGLVLCLSGMLLHGMNK-----RHQRLSRI 386

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BLAST of slc35c-4 vs. Ensembl Celegans
Match: Y47G6A.7 (pep chromosome:WBcel235:I:3502738:3508421:1 gene:WBGene00021637.1 transcript:Y47G6A.7a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y47G6A.7)

HSP 1 Score: 95.5153 bits (236), Expect = 4.113e-23
Identity = 49/121 (40.50%), Postives = 75/121 (61.98%), Query Frame = 3

Query:  105 GLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLH 467
             + HP+DM+ HVQPWM++ ++P+    EG E+  +S  F F    +   +  ++  G +LAF ME +EYL++  TS +TL I GI+KE+  L LA  +NKD +  +N  GL+ CL G+ LH
Sbjct:  255 AVRHPLDMVAHVQPWMMIPIIPMIWLFEGAEINWNS-VFSFKGHYDPWLVMGLIAGGGLLAFCMEMSEYLLLVNTSGITLNIFGIVKEVATLLLAHIVNKDTLTELNICGLVLCLSGMLLH 374

[Close]

BLAST of slc35c-4 vs. Ensembl Celegans
Match: Y47G6A.7 (pep chromosome:WBcel235:I:3502738:3508421:1 gene:WBGene00021637.1 transcript:Y47G6A.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y47G6A.7)

HSP 1 Score: 95.5153 bits (236), Expect = 4.113e-23
Identity = 49/121 (40.50%), Postives = 75/121 (61.98%), Query Frame = 3

Query:  105 GLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLH 467
             + HP+DM+ HVQPWM++ ++P+    EG E+  +S  F F    +   +  ++  G +LAF ME +EYL++  TS +TL I GI+KE+  L LA  +NKD +  +N  GL+ CL G+ LH
Sbjct:  255 AVRHPLDMVAHVQPWMMIPIIPMIWLFEGAEINWNS-VFSFKGHYDPWLVMGLIAGGGLLAFCMEMSEYLLLVNTSGITLNIFGIVKEVATLLLAHIVNKDTLTELNICGLVLCLSGMLLH 374

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BLAST of slc35c-4 vs. Ensembl Fly
Match: CG14971 (gene:FBgn0035449 transcript:FBtr0073143)

HSP 1 Score: 117.087 bits (292), Expect = 1.140e-30
Identity = 66/152 (43.42%), Postives = 95/152 (62.50%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEI----PEISPDD 545
            LGL +PIDMIY++QPWMI  L+PL  GIEG  + +  +    H S E       +  GA+LAF ME +E+L++ +TSSLTL I+GI K+I  L LAV I KD ++ IN++GLI CL GI  H++ K+    + Q+   +++     E SP +
Sbjct:  261 LGLHNPIDMIYYMQPWMIASLVPLVIGIEGAGLIAVIEDLHNHTSNEITWAIARISAGALLAFLMEFSEFLVLCKTSSLTLSIAGIFKDICQLALAVTIRKDHLSVINYIGLIICLAGIVCHLLHKYSNMKEMQRQQELQLDNDQEESSPGE 412

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BLAST of slc35c-4 vs. Ensembl Zebrafish
Match: slc35c2 (solute carrier family 35 member C2 [Source:ZFIN;Acc:ZDB-GENE-030131-2202])

HSP 1 Score: 100.523 bits (249), Expect = 2.566e-24
Identity = 58/126 (46.03%), Postives = 82/126 (65.08%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIK 479
            LGL +PID +YH+QP M L L PL    EGL V+++ K F     +  L     L  G +LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV+   D+++++N++G   CL GISLH+ +K
Sbjct:  189 LGLQNPIDTMYHLQPLMFLGLFPLFLLNEGLSVSTTEKLFRVSELSHLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMSTVNWLGFAVCLSGISLHIGLK 314

[Close]

BLAST of slc35c-4 vs. Ensembl Zebrafish
Match: slc35c2 (solute carrier family 35 member C2 [Source:ZFIN;Acc:ZDB-GENE-030131-2202])

HSP 1 Score: 100.523 bits (249), Expect = 2.675e-24
Identity = 58/126 (46.03%), Postives = 82/126 (65.08%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIK 479
            LGL +PID +YH+QP M L L PL    EGL V+++ K F     +  L     L  G +LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV+   D+++++N++G   CL GISLH+ +K
Sbjct:  189 LGLQNPIDTMYHLQPLMFLGLFPLFLLNEGLSVSTTEKLFRVSELSHLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMSTVNWLGFAVCLSGISLHIGLK 314

[Close]

BLAST of slc35c-4 vs. Ensembl Zebrafish
Match: slc35c2 (solute carrier family 35 member C2 [Source:ZFIN;Acc:ZDB-GENE-030131-2202])

HSP 1 Score: 100.523 bits (249), Expect = 2.701e-24
Identity = 58/126 (46.03%), Postives = 82/126 (65.08%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIK 479
            LGL +PID +YH+QP M L L PL    EGL V+++ K F     +  L     L  G +LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV+   D+++++N++G   CL GISLH+ +K
Sbjct:  189 LGLQNPIDTMYHLQPLMFLGLFPLFLLNEGLSVSTTEKLFRVSELSHLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMSTVNWLGFAVCLSGISLHIGLK 314

[Close]

BLAST of slc35c-4 vs. Ensembl Zebrafish
Match: slc35c2 (solute carrier family 35 member C2 [Source:ZFIN;Acc:ZDB-GENE-030131-2202])

HSP 1 Score: 96.6709 bits (239), Expect = 1.591e-23
Identity = 61/144 (42.36%), Postives = 89/144 (61.81%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIK-FRYSNDDQKVSRIEIPE 530
            LGL +PID +YH+QP M L L PL    EGL V+++ K F     +  L     L  G +LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV+   D+++++N++G   CL GISLH+ +K +R   +   V  + + E
Sbjct:  189 LGLQNPIDTMYHLQPLMFLGLFPLFLLNEGLSVSTTEKLFRVSELSHLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMSTVNWLGFAVCLSGISLHIGLKTYRNKGNGPMVRHLPVRE 332

[Close]

BLAST of slc35c-4 vs. Ensembl Zebrafish
Match: slc35c2 (solute carrier family 35 member C2 [Source:ZFIN;Acc:ZDB-GENE-030131-2202])

HSP 1 Score: 94.7449 bits (234), Expect = 8.194e-23
Identity = 60/133 (45.11%), Postives = 84/133 (63.16%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSND 497
             LGL +PID +YH+QP M L L PL    EGL V+++ K F     +  L     L  G +LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV+   D+++++N++G   CL GISLH+ +K  Y N 
Sbjct:  188 ELGLQNPIDTMYHLQPLMFLGLFPLFLLNEGLSVSTTEKLFRVSELSHLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMSTVNWLGFAVCLSGISLHIGLK-TYRNK 319

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BLAST of slc35c-4 vs. Ensembl Xenopus
Match: ENSXETT00000029795.1 (solute carrier family 35 member C2-like [Source:NCBI gene;Acc:101731373])

HSP 1 Score: 97.4413 bits (241), Expect = 2.668e-24
Identity = 60/134 (44.78%), Postives = 89/134 (66.42%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQ 503
            LGL +PID ++H+QP M L L PL  GIEGL V +S + F   +S + L L   L  G +LAF +  +E+L+VS+TSSLTL I+GI KE+ +L LA  +  DE++ +N++G   C+ GI+LHV +K  +S  ++
Sbjct:  102 LGLQNPIDTMFHLQPVMFLSLFPLFVGIEGLHVATSEQLFCSQDSHQLLALLATLALGGLLAFGLGFSEFLLVSKTSSLTLSIAGIFKELCVLLLATHLLGDELSILNWLGFAVCIAGIALHVALKTTHSRVEE 235

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BLAST of slc35c-4 vs. Ensembl Mouse
Match: Slc35c2 (solute carrier family 35, member C2 [Source:MGI Symbol;Acc:MGI:2385166])

HSP 1 Score: 105.531 bits (262), Expect = 1.124e-26
Identity = 63/133 (47.37%), Postives = 88/133 (66.17%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDD 500
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   LL G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAIFEGLHLSTSEKIFRFQDTGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGD 324

[Close]

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDD 500
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   LL G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAIFEGLHLSTSEKIFRFQDTGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGD 324

[Close]

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDD 500
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   LL G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAIFEGLHLSTSEKIFRFQDTGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGD 324

[Close]

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDD 500
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   LL G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAIFEGLHLSTSEKIFRFQDTGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGD 324

[Close]

BLAST of slc35c-4 vs. UniProt/SwissProt
Match: sp|Q9NQQ7|S35C2_HUMAN (Solute carrier family 35 member C2 OS=Homo sapiens OX=9606 GN=SLC35C2 PE=1 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 6.985e-30
Identity = 65/147 (44.22%), Postives = 92/147 (62.59%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   L  G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D     ++    SPD
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPD 338

[Close]

BLAST of slc35c-4 vs. UniProt/SwissProt
Match: sp|Q8VCX2|S35C2_MOUSE (Solute carrier family 35 member C2 OS=Mus musculus OX=10090 GN=Slc35c2 PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 7.862e-26
Identity = 63/133 (47.37%), Postives = 88/133 (66.17%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDD 500
            LGL +PID ++H+QP M L L PL +  EGL +++S K F F ++   L +   LL G ILAF +  +E+L+VSRTSSLTL I+GI KE+  L LA  +  D+I+ +N++G   CL GISLHV +K  +S  D
Sbjct:  192 LGLQNPIDTMFHLQPLMFLGLFPLFAIFEGLHLSTSEKIFRFQDTGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGD 324

[Close]

BLAST of slc35c-4 vs. UniProt/SwissProt
Match: sp|Q8H184|PT106_ARATH (Probable sugar phosphate/phosphate translocator At1g06470 OS=Arabidopsis thaliana OX=3702 GN=At1g06470 PE=2 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 7.592e-9
Identity = 40/130 (30.77%), Postives = 70/130 (53.85%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFG---FHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKF 482
             GL +P   +  V P     ++ +++G+  L +   S+F     F +        F++L+G  LAF M  TEY++VS TS++T+ I+G++KE   + +AV    DE   +  VGL+  ++G+SL    K+
Sbjct:  253 FGLKNPFIFMSCVAP-----VMAIATGLLSLLLDPWSEFRDNKYFDSGAHFARTCFLMLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSLFNWYKY 377

[Close]

BLAST of slc35c-4 vs. UniProt/SwissProt
Match: sp|Q10354|YDB1_SCHPO (Uncharacterized transporter C22E12.01 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC22E12.01 PE=3 SV=2)

HSP 1 Score: 52.373 bits (124), Expect = 5.555e-7
Identity = 41/142 (28.87%), Postives = 66/142 (46.48%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTE-GLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIE 521
            H   S+P   ++ + P M LFLL     + GL      +F       E G  +  V+L    LAF M  +E+ ++ +TS +TL + GI+KEI  +  +     D +  IN VGL+  L GI ++   +    N  +    +E
Sbjct:  230 HPWTSNPFTSLFALTPLMFLFLL-----VAGLIFEGPVRFIESPAWKEFGPFMSVVILVPGTLAFFMVASEFGLIQKTSIVTLSVCGILKEIITIIASTLFYHDILLPINIVGLVITLCGIGVYNYYRITKGNKKEAEKEVE 366

[Close]

BLAST of slc35c-4 vs. UniProt/SwissProt
Match: sp|Q9SUV2|PT432_ARATH (Probable sugar phosphate/phosphate translocator At4g32390 OS=Arabidopsis thaliana OX=3702 GN=At4g32390 PE=3 SV=1)

HSP 1 Score: 50.447 bits (119), Expect = 2.464e-6
Identity = 34/133 (25.56%), Postives = 66/133 (49.62%), Query Frame = 3

Query:  114 HPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISL--HVIIKFRYSNDDQK 506
            +PI  +Y+V P  ++FL      +E L +   +  F F         F +    ++ AFA+    +L+V +TS+LT+ ++G++K+  L+  +  + KD +  +N  G     LG++   H  ++   + D QK
Sbjct:  197 NPITSLYYVAPCCLVFLFFPWIFVE-LPILRETSSFHFD--------FVIFGTNSVCAFALNLAVFLLVGKTSALTMNVAGVVKDWLLIAFSWSVIKDTVTPLNLFGYGLAFLGVAYYNHCKLQALKAKDAQK 320

[Close]

BLAST of slc35c-4 vs. TrEMBL
Match: A0A0H3YKF8 (Slc35c-4 OS=Schmidtea mediterranea OX=79327 GN=slc35c-4 PE=2 SV=1)

HSP 1 Score: 298.13 bits (762), Expect = 4.302e-100
Identity = 149/155 (96.13%), Postives = 149/155 (96.13%), Query Frame = 3

Query:   81 LFVIDLHLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD 545
            LF      GLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD
Sbjct:   71 LFTQHDKFGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD 225

[Close]

BLAST of slc35c-4 vs. TrEMBL
Match: A0A0H3YFJ8 (Slc35c-3 OS=Schmidtea mediterranea OX=79327 GN=slc35c-3 PE=2 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 9.123e-40
Identity = 71/136 (52.21%), Postives = 101/136 (74.26%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKV 509
            +GL +PIDMIYH+QPWMIL LLPLS+  EG+E+ S+  FF F +  + +  F  L+ GA++AF +EC+EYL+++ TSSLTL I+GIIKE+ +L LA KIN D++N+IN +GL  C+LGI LHV +K +++     V
Sbjct:  190 IGLQNPIDMIYHIQPWMILTLLPLSAWFEGIEIISTKDFFRFSDINDLIINFSTLMSGAMIAFCLECSEYLVITHTSSLTLSIAGIIKEVCVLYLATKINGDQLNNINIIGLSICMLGILLHVAMKIKHNKSVNNV 325

[Close]

BLAST of slc35c-4 vs. TrEMBL
Match: R7T4H5 (TPT domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_224289 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 1.758e-39
Identity = 74/137 (54.01%), Postives = 100/137 (72.99%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVS 512
            LG+ HP+DM+YH+QPWM+L LLPL+ G EG  +  S   FGFH S+       +L+ GA LAF +E +E+L+VS+TSSLTL ISGI KEI  L LAV INKD ++ IN +GL+ CLLGI++HVI+K  +S D+++V 
Sbjct:  213 LGVHHPLDMMYHIQPWMMLTLLPLAGGFEGRRLAISPHAFGFHESSLLARDMAILMLGAFLAFMLEMSEFLLVSKTSSLTLSISGIAKEIVTLCLAVVINKDPMSPINGIGLVVCLLGITIHVILKAVHSEDEKEVK 349

[Close]

BLAST of slc35c-4 vs. TrEMBL
Match: A0A4D5RVX6 (Putative solute carrier family 35 member c2 OS=Ixodes scapularis OX=6945 PE=4 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 2.294e-37
Identity = 70/135 (51.85%), Postives = 97/135 (71.85%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQ 503
             +GL +PIDMI+HVQPWMIL LLPL+   EG+ + +S K F FH     +     +L G++LAF ME +EYL+++ TSSLTL I+GI+KE+  L LAV  + DEI+ +NFVGL+ CLLGI+LHV++K   SN++ 
Sbjct:   39 EVGLGNPIDMIFHVQPWMILGLLPLAIAFEGIPIATSEKVFRFHEVEMLVRTGQYVLAGSVLAFFMELSEYLLLTYTSSLTLSIAGIVKEVCTLYLAVNYSGDEISFMNFVGLVICLLGIALHVLVKSLNSNEEN 173

[Close]

BLAST of slc35c-4 vs. TrEMBL
Match: A0A1I8HNZ9 (TPT domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 6.893e-37
Identity = 69/136 (50.74%), Postives = 92/136 (67.65%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKV 509
            LGL++P+DMIYHVQPWM+L LLPLS   EG E+ +++  F   ++T       +LL GA LAF +EC+EYL++SRTSSLTL +SGI KE+  + LA  IN D IN +N+ G+  CL GI LH  +K   S+ D  V
Sbjct:  207 LGLANPVDMIYHVQPWMVLVLLPLSVAFEGTEIATTANLFRASSATAAFGTVRILLVGAFLAFGLECSEYLLLSRTSSLTLSVSGIFKEVCTIVLAAGINDDVINPVNWAGMALCLSGIGLHCGLKAAASSADATV 342

[Close]

BLAST of slc35c-4 vs. Ensembl Cavefish
Match: ENSAMXT00000013197.2 (pep primary_assembly:Astyanax_mexicanus-2.0:15:25809036:25860556:1 gene:ENSAMXG00000012384.2 transcript:ENSAMXT00000013197.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 116.701 bits (291), Expect = 6.770e-30
Identity = 62/132 (46.97%), Postives = 83/132 (62.88%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSND 497
            LGL +PID +YH+QP M L L PL    EGL +++S K F        L     L  G  LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV    D+++++N++G + CL GISLHV +K  YS D
Sbjct:  189 LGLQNPIDTMYHLQPLMFLGLFPLFVVNEGLGLSTSEKLFRVSELQPLLYSLLTLSVGGTLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVGFMGDKMSTVNWLGFVVCLAGISLHVGLKTYYSKD 320

[Close]

BLAST of slc35c-4 vs. Ensembl Cavefish
Match: ENSAMXT00000044703.1 (pep primary_assembly:Astyanax_mexicanus-2.0:15:25808986:25818566:1 gene:ENSAMXG00000012384.2 transcript:ENSAMXT00000044703.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.612 bits (270), Expect = 4.157e-28
Identity = 64/148 (43.24%), Postives = 87/148 (58.78%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPD 542
             LGL +PID +YH+QP M L L PL    EGL +++S K F        L     L  G  LAF +  +E+L+VSRTSSLTL I+GI KE+  L LAV    D+++++N++G + CL GISLHV +K  YS  +    R      +PD
Sbjct:  188 ELGLQNPIDTMYHLQPLMFLGLFPLFVVNEGLGLSTSEKLFRVSELQPLLYSLLTLSVGGTLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVGFMGDKMSTVNWLGFVVCLAGISLHVGLKTYYSKGNGSSLRPLPGRDNPD 335

[Close]

BLAST of slc35c-4 vs. Ensembl Sea Lamprey
Match: slc35c2 (solute carrier family 35 member C2 [Source:ZFIN;Acc:ZDB-GENE-030131-2202])

HSP 1 Score: 109.383 bits (272), Expect = 2.592e-29
Identity = 60/127 (47.24%), Postives = 81/127 (63.78%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIK 479
             LGL +P+D +YH+QP M+  L PL    EG+ +  + K FGFH+S   L     L  G +LAF +  +E+L+VS+TS LTL ISGI KE+  L LA  IN D ++ +N+VG   CL GISLHV +K
Sbjct:  189 ELGLHNPVDALYHLQPLMLAALFPLFLYNEGVSLACTEKLFGFHDSEVLLWSVGTLALGGVLAFGLSFSEFLLVSQTSGLTLSISGIFKEVCTLVLATHINGDIMSPLNWVGFGVCLAGISLHVALK 315

[Close]

BLAST of slc35c-4 vs. Ensembl Nematostella
Match: EDO40549 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S701])

HSP 1 Score: 106.686 bits (265), Expect = 9.229e-28
Identity = 55/135 (40.74%), Postives = 83/135 (61.48%), Query Frame = 3

Query:  102 LGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQK 506
            LGL +P+D IYH+QP M L L PL+  IEG  +  S + F   +    +    ++ +G  LAF +  +E++++S TSSLTL ISGI KE+  L LA +   DE+N +NF GL+ CL GI++HV+      +++ K
Sbjct:  191 LGLHNPLDTIYHLQPLMALALTPLAFTIEGPSMALSEQLFNAPSMHVAITSASMVFFGCFLAFMLSVSEFMLLSHTSSLTLSISGIFKEVCTLSLATEFGGDEMNIVNFCGLVLCLTGIAVHVVTNASKDSENGK 325

[Close]

BLAST of slc35c-4 vs. Ensembl Medaka
Match: slc35c2 (solute carrier family 35 member C2 [Source:NCBI gene;Acc:101157129])

HSP 1 Score: 106.301 bits (264), Expect = 3.483e-27
Identity = 63/156 (40.38%), Postives = 89/156 (57.05%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDD-------QKVSRIEIPEISPDD 545
             LGL +PID +YH+QP M L L PL    E L ++ S K F        L   F L  G +LAF +  +E+L+VS+TSSLTL ISGI KE+  L LA  +  DE++ +N++G   CL GISLHV +K  YS +         + S++ +P +  + 
Sbjct:  188 ELGLQNPIDAMYHLQPLMFLGLFPLFLYNEALNLSMSEKLFRVTELRPLLYSLFTLTVGGLLAFGLGFSEFLLVSKTSSLTLSISGIFKEVCTLLLAASLMGDELSMLNWLGFAVCLCGISLHVGLKTYYSKNKLPSLQQHNRSSKLALPLLRQES 343

[Close]

BLAST of slc35c-4 vs. Ensembl Medaka
Match: slc35c2 (solute carrier family 35 member C2 [Source:NCBI gene;Acc:101157129])

HSP 1 Score: 104.375 bits (259), Expect = 1.154e-26
Identity = 61/135 (45.19%), Postives = 80/135 (59.26%), Query Frame = 3

Query:   99 HLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQ 503
             LGL +PID +YH+QP M L L PL    E L ++ S K F        L   F L  G +LAF +  +E+L+VS+TSSLTL ISGI KE+  L LA  +  DE++ +N++G   CL GISLHV +K  YS    
Sbjct:  188 ELGLQNPIDAMYHLQPLMFLGLFPLFLYNEALNLSMSEKLFRVTELRPLLYSLFTLTVGGLLAFGLGFSEFLLVSKTSSLTLSISGIFKEVCTLLLAASLMGDELSMLNWLGFAVCLCGISLHVGLKTYYSKSKS 322

[Close]

BLAST of slc35c-4 vs. Planmine SMEST
Match: SMESG000017437.1 (SMESG000017437.1)

HSP 1 Score: 300.442 bits (768), Expect = 8.285e-103
Identity = 149/155 (96.13%), Postives = 149/155 (96.13%), Query Frame = 3

Query:   81 LFVIDLHLGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD 545
            LF      GLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD
Sbjct:  187 LFTQHDKFGLSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD 341

[Close]

BLAST of slc35c-4 vs. Planmine SMEST
Match: SMESG000055160.1 (SMESG000055160.1)

HSP 1 Score: 145.591 bits (366), Expect = 1.136e-42
Identity = 69/134 (51.49%), Postives = 100/134 (74.63%), Query Frame = 3

Query:  108 LSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKV 509
            +++PIDMIYH+QPWMIL LLPLS+  EG+E+ S+  FF F +  + +  F  L+ GA++AF +EC+EYL+++ TSSLTL I+GIIKE+ +L LA KIN D++N+IN +GL  C+LGI LHV +K +++     V
Sbjct:  131 ITNPIDMIYHIQPWMILTLLPLSAWFEGIEIISTKDFFRFSDINDLIINFSTLMSGAMIAFCLECSEYLVITHTSSLTLSIAGIIKEVCVLYLATKINGDQLNNINIIGLSICMLGILLHVAMKIKHNKSVNNV 264

[Close]

BLAST of slc35c-4 vs. Planmine SMEST
Match: SMESG000055160.1 (SMESG000055160.1)

HSP 1 Score: 145.591 bits (366), Expect = 3.910e-42
Identity = 69/134 (51.49%), Postives = 100/134 (74.63%), Query Frame = 3

Query:  108 LSHPIDMIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYGAILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSINFVGLIFCLLGISLHVIIKFRYSNDDQKV 509
            +++PIDMIYH+QPWMIL LLPLS+  EG+E+ S+  FF F +  + +  F  L+ GA++AF +EC+EYL+++ TSSLTL I+GIIKE+ +L LA KIN D++N+IN +GL  C+LGI LHV +K +++     V
Sbjct:  178 ITNPIDMIYHIQPWMILTLLPLSAWFEGIEIISTKDFFRFSDINDLIINFSTLMSGAMIAFCLECSEYLVITHTSSLTLSIAGIIKEVCVLYLATKINGDQLNNINIIGLSICMLGILLHVAMKIKHNKSVNNV 311

The following BLAST results are available for this feature:

BLAST of slc35c-4 vs. Ensembl Human
BLAST of slc35c-4 vs. Ensembl Celegans
BLAST of slc35c-4 vs. Ensembl Fly
BLAST of slc35c-4 vs. Ensembl Zebrafish
BLAST of slc35c-4 vs. Ensembl Xenopus
BLAST of slc35c-4 vs. Ensembl Mouse
BLAST of slc35c-4 vs. UniProt/SwissProt
BLAST of slc35c-4 vs. TrEMBL
BLAST of slc35c-4 vs. Ensembl Cavefish
BLAST of slc35c-4 vs. Ensembl Sea Lamprey
BLAST of slc35c-4 vs. Ensembl Yeast
BLAST of slc35c-4 vs. Ensembl Nematostella
BLAST of slc35c-4 vs. Ensembl Medaka
BLAST of slc35c-4 vs. Planmine SMEST

BLAST of slc35c-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC35C2	1.273e-30	44.22	solute carrier family 35 member C2 [Source:HGNC Sy...	[more]
SLC35C2	1.454e-30	44.22	solute carrier family 35 member C2 [Source:HGNC Sy...	[more]
SLC35C2	1.454e-30	44.22	solute carrier family 35 member C2 [Source:HGNC Sy...	[more]
SLC35C2	1.454e-30	44.22	solute carrier family 35 member C2 [Source:HGNC Sy...	[more]
SLC35C2	2.007e-30	44.22	solute carrier family 35 member C2 [Source:HGNC Sy...	[more]

BLAST of slc35c-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Y47G6A.7	4.962e-24	39.13	pep chromosome:WBcel235:I:3502738:3508421:1 gene:W...	[more]
Y47G6A.7	4.962e-24	39.13	pep chromosome:WBcel235:I:3502738:3508421:1 gene:W...	[more]
Y47G6A.7	4.113e-23	40.50	pep chromosome:WBcel235:I:3502738:3508421:1 gene:W...	[more]
Y47G6A.7	4.113e-23	40.50	pep chromosome:WBcel235:I:3502738:3508421:1 gene:W...	[more]

BLAST of slc35c-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
CG14971	1.140e-30	43.42	gene:FBgn0035449 transcript:FBtr0073143	[more]

BLAST of slc35c-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc35c2	2.566e-24	46.03	solute carrier family 35 member C2 [Source:ZFIN;Ac...	[more]
slc35c2	2.675e-24	46.03	solute carrier family 35 member C2 [Source:ZFIN;Ac...	[more]
slc35c2	2.701e-24	46.03	solute carrier family 35 member C2 [Source:ZFIN;Ac...	[more]
slc35c2	1.591e-23	42.36	solute carrier family 35 member C2 [Source:ZFIN;Ac...	[more]
slc35c2	8.194e-23	45.11	solute carrier family 35 member C2 [Source:ZFIN;Ac...	[more]

BLAST of slc35c-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSXETT00000029795.1	2.668e-24	44.78	solute carrier family 35 member C2-like [Source:NC...	[more]

BLAST of slc35c-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Slc35c2	1.124e-26	47.37	solute carrier family 35, member C2 [Source:MGI Sy...	[more]
Slc35c2	1.124e-26	47.37	solute carrier family 35, member C2 [Source:MGI Sy...	[more]
Slc35c2	1.124e-26	47.37	solute carrier family 35, member C2 [Source:MGI Sy...	[more]
Slc35c2	1.124e-26	47.37	solute carrier family 35, member C2 [Source:MGI Sy...	[more]

BLAST of slc35c-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9NQQ7\|S35C2_HUMAN	6.985e-30	44.22	Solute carrier family 35 member C2 OS=Homo sapiens...	[more]
sp\|Q8VCX2\|S35C2_MOUSE	7.862e-26	47.37	Solute carrier family 35 member C2 OS=Mus musculus...	[more]
sp\|Q8H184\|PT106_ARATH	7.592e-9	30.77	Probable sugar phosphate/phosphate translocator At...	[more]
sp\|Q10354\|YDB1_SCHPO	5.555e-7	28.87	Uncharacterized transporter C22E12.01 OS=Schizosac...	[more]
sp\|Q9SUV2\|PT432_ARATH	2.464e-6	25.56	Probable sugar phosphate/phosphate translocator At...	[more]

BLAST of slc35c-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YKF8	4.302e-100	96.13	Slc35c-4 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A0H3YFJ8	9.123e-40	52.21	Slc35c-3 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
R7T4H5	1.758e-39	54.01	TPT domain-containing protein OS=Capitella teleta ...	[more]
A0A4D5RVX6	2.294e-37	51.85	Putative solute carrier family 35 member c2 OS=Ixo...	[more]
A0A1I8HNZ9	6.893e-37	50.74	TPT domain-containing protein OS=Macrostomum ligna...	[more]

BLAST of slc35c-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSAMXT00000013197.2	6.770e-30	46.97	pep primary_assembly:Astyanax_mexicanus-2.0:15:258...	[more]
ENSAMXT00000044703.1	4.157e-28	43.24	pep primary_assembly:Astyanax_mexicanus-2.0:15:258...	[more]

BLAST of slc35c-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
slc35c2	2.592e-29	47.24	solute carrier family 35 member C2 [Source:ZFIN;Ac...	[more]

BLAST of slc35c-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of slc35c-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO40549	9.229e-28	40.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc35c-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
slc35c2	3.483e-27	40.38	solute carrier family 35 member C2 [Source:NCBI ge...	[more]
slc35c2	1.154e-26	45.19	solute carrier family 35 member C2 [Source:NCBI ge...	[more]

BLAST of slc35c-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000017437.1	8.285e-103	96.13	SMESG000017437.1	[more]
SMESG000055160.1	1.136e-42	51.49	SMESG000055160.1	[more]
SMESG000055160.1	3.910e-42	51.49	SMESG000055160.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30012061
GenBank	AKN21648.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30012061 ID=SMED30012061|Name=slc35c-4|organism=Schmidtea mediterranea sexual|type=transcript|length=601bp
AAAATTAGGACTGTAATTAAAATTTATTTTAGATTTCGAAATAAAATTTC
TTTTAACAACTTATAAAATATTTCCCGGGCCTATTTGTAATTGACTTACA
TTTAGGTCTATCACACCCGATTGATATGATTTATCATGTTCAACCATGGA
TGATTTTATTTCTGTTGCCGTTATCCTCCGGAATCGAGGGTTTGGAAGTT
ACTTCATCTTCCAAATTTTTTGGTTTCCACAATTCTACCGAAGGGCTAGA
TCTGTTTTTCGTGTTATTATATGGTGCAATTTTGGCTTTTGCCATGGAAT
GTACAGAATACTTAATGGTTTCTAGAACATCAAGTCTTACTCTGTGTATA
TCGGGAATTATAAAAGAAATAACTTTGCTTGGATTAGCAGTCAAAATCAA
CAAGGATGAAATAAACAGTATAAATTTTGTTGGTTTAATATTTTGCTTGC
TCGGAATCTCGTTACATGTTATAATCAAATTTAGATATAGCAATGATGAT
CAAAAGGTCTCGCGGATCGAGATCCCAGAGATTTCTCCTGATGATTGATG
ATTATTGTCTTTCTTTTTTATTTTTTAAAAAAATATTTGAAAAATTTAGA
T

protein sequence of SMED30012061-orf-1

>SMED30012061-orf-1 ID=SMED30012061-orf-1|Name=SMED30012061-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=141bp
MIYHVQPWMILFLLPLSSGIEGLEVTSSSKFFGFHNSTEGLDLFFVLLYG
AILAFAMECTEYLMVSRTSSLTLCISGIIKEITLLGLAVKINKDEINSIN
FVGLIFCLLGISLHVIIKFRYSNDDQKVSRIEIPEISPDD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PANTHER	PTHR11132	SOLUTE CARRIER FAMILY 35	coord: 1..126
None	No IPR available	PANTHER	PTHR11132:SF238	SOLUTE CARRIER FAMILY 35 MEMBER C2	coord: 1..126
None	No IPR available	SIGNALP_EUK	SignalP-TM	SignalP-TM	coord: 1..19 score: 0.733
None	No IPR available	TMHMM	TMhelix		coord: 43..65
None	No IPR available	TMHMM	TMhelix		coord: 98..117

Main menu

slc35c-4

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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