arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30012050 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:HGNC Symbol;Acc:HGNC:16924]) HSP 1 Score: 115.161 bits (287), Expect = 4.422e-25 Identity = 72/214 (33.64%), Postives = 109/214 (50.93%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
+F E+ + +W I + +IA + ++ ++I+ NESN+ CADC P+P+W SINLCV++C C+G HRSL S+++S +D IW + LIE+ IGN+ +N FW N Q + E I KY E KF T +L+ E+ L ++V DV TM L S + L+A+ + Q LQ +FL
Sbjct: 656 SFSFTAETEKEKQDW--IEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNE-LIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 866 HSP 2 Score: 59.3066 bits (142), Expect = 4.617e-8 Identity = 35/142 (24.65%), Postives = 67/142 (47.18%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMD 2408
L N PI+ N I F+ GL ++I++K G I+ L E +K F + + + DV + LK + ++ ++T L+ + A ++ ++ + + S+P +N L +E LY +QK ++ N M+
Sbjct: 1122 QLSKNDVPIIVN---SCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN 1260
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]) HSP 1 Score: 112.849 bits (281), Expect = 1.648e-24 Identity = 73/272 (26.84%), Postives = 131/272 (48.16%), Query Frame = 3
Query: 534 YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
Y+ + D+ + +Y+NL E+ I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P P+W SINLCV++C C+G HR L S+++S +D+++W ++ LIE+ ++GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D E L +A + Q LQ +FL
Sbjct: 217 YVAVVGDK--VQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTET-LIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPE-APTPLALAEQAGQTLQMEFL 476 HSP 2 Score: 55.8398 bits (133), Expect = 4.507e-7 Identity = 41/171 (23.98%), Postives = 86/171 (50.29%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKE 2540
+ + +I GL SE I+RK G K L E + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M+ +LA+ ++ D + +++DLI+++ VF +E
Sbjct: 736 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD-GQDYKAGRVVEDLINHYVVVFSVDEEE 905
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]) HSP 1 Score: 112.849 bits (281), Expect = 1.720e-24 Identity = 73/272 (26.84%), Postives = 131/272 (48.16%), Query Frame = 3
Query: 534 YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
Y+ + D+ + +Y+NL E+ I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P P+W SINLCV++C C+G HR L S+++S +D+++W ++ LIE+ ++GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D E L +A + Q LQ +FL
Sbjct: 457 YVAVVGDK--VQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTET-LIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPE-APTPLALAEQAGQTLQMEFL 716 HSP 2 Score: 55.4546 bits (132), Expect = 7.186e-7 Identity = 40/165 (24.24%), Postives = 84/165 (50.91%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+ + +I GL SE I+RK G K L E + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M+ +LA+ ++ D + +++DLI+++ VF
Sbjct: 976 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD-GQDYKAGRVVEDLINHYVVVF 1139
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]) HSP 1 Score: 112.849 bits (281), Expect = 1.787e-24 Identity = 73/272 (26.84%), Postives = 131/272 (48.16%), Query Frame = 3
Query: 534 YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
Y+ + D+ + +Y+NL E+ I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P P+W SINLCV++C C+G HR L S+++S +D+++W ++ LIE+ ++GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D E L +A + Q LQ +FL
Sbjct: 457 YVAVVGDK--VQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTET-LIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPE-APTPLALAEQAGQTLQMEFL 716 HSP 2 Score: 55.4546 bits (132), Expect = 6.897e-7 Identity = 40/165 (24.24%), Postives = 84/165 (50.91%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+ + +I GL SE I+RK G K L E + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M+ +LA+ ++ D + +++DLI+++ VF
Sbjct: 976 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD-GQDYKAGRVVEDLINHYVVVF 1139
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]) HSP 1 Score: 112.849 bits (281), Expect = 1.904e-24 Identity = 73/272 (26.84%), Postives = 131/272 (48.16%), Query Frame = 3
Query: 534 YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
Y+ + D+ + +Y+NL E+ I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P P+W SINLCV++C C+G HR L S+++S +D+++W ++ LIE+ ++GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D E L +A + Q LQ +FL
Sbjct: 212 YVAVVGDK--VQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTET-LIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPE-APTPLALAEQAGQTLQMEFL 471 HSP 2 Score: 55.8398 bits (133), Expect = 4.974e-7 Identity = 41/171 (23.98%), Postives = 86/171 (50.29%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKE 2540
+ + +I GL SE I+RK G K L E + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M+ +LA+ ++ D + +++DLI+++ VF +E
Sbjct: 731 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD-GQDYKAGRVVEDLINHYVVVFSVDEEE 900
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-1 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-1 Truncated ctn-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XXH8]) HSP 1 Score: 85.8853 bits (211), Expect = 6.140e-17 Identity = 43/121 (35.54%), Postives = 68/121 (56.20%), Query Frame = 3
Query: 810 KQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE----------INSKYIEKKFIDTE 1142
+Q+ N++CADCG P P+WVSINL V+LCI CSG HRSL S+++S +D D+ L +++ +GN N + + + +I P ++E I +KY+E++F E
Sbjct: 200 EQVRRVPGNEVCADCGSPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDSI---DNELRDVLLALGNRQVNEIFLAHLPPADSIVPPQINEKSARPAREAWIKAKYVERRFAVAE 317
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-1 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-1 Truncated ctn-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XXH8]) HSP 1 Score: 85.8853 bits (211), Expect = 8.720e-17 Identity = 43/121 (35.54%), Postives = 68/121 (56.20%), Query Frame = 3
Query: 810 KQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE----------INSKYIEKKFIDTE 1142
+Q+ N++CADCG P P+WVSINL V+LCI CSG HRSL S+++S +D D+ L +++ +GN N + + + +I P ++E I +KY+E++F E
Sbjct: 367 EQVRRVPGNEVCADCGSPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDS---IDNELRDVLLALGNRQVNEIFLAHLPPADSIVPPQINEKSARPAREAWIKAKYVERRFAVAE 484
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-1 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-1 Truncated ctn-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XXH8]) HSP 1 Score: 85.8853 bits (211), Expect = 9.168e-17 Identity = 43/121 (35.54%), Postives = 68/121 (56.20%), Query Frame = 3
Query: 810 KQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE----------INSKYIEKKFIDTE 1142
+Q+ N++CADCG P P+WVSINL V+LCI CSG HRSL S+++S +D D+ L +++ +GN N + + + +I P ++E I +KY+E++F E
Sbjct: 451 EQVRRVPGNEVCADCGSPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDSI---DNELRDVLLALGNRQVNEIFLAHLPPADSIVPPQINEKSARPAREAWIKAKYVERRFAVAE 568
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-2 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XX14]) HSP 1 Score: 85.5001 bits (210), Expect = 1.502e-16 Identity = 47/132 (35.61%), Postives = 72/132 (54.55%), Query Frame = 3
Query: 831 SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW---YKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFIN--LSDNEIKNRLRSSVATDDVF 1211
N CADCG P+ EW SINL +I+CI CSG+HR+L + S+++ LDQ W L +M+ IGN+ +N W N + T P E ++I++K++ F+ S + ++L S+V DV
Sbjct: 599 GNGRCADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQ--WPVEHLA-VMQAIGNDKANEMWEFGLLNGERKPT--PESSREEKERFIDRKYVQKAFLKPIASGEPVTSQLISAVLARDVM 725
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Match: cnt-2 (Arf-GAP with ANK repeat and PH domain-containing protein cnt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XX14]) HSP 1 Score: 85.5001 bits (210), Expect = 1.510e-16 Identity = 47/132 (35.61%), Postives = 72/132 (54.55%), Query Frame = 3
Query: 831 SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW---YKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFIN--LSDNEIKNRLRSSVATDDVF 1211
N CADCG P+ EW SINL +I+CI CSG+HR+L + S+++ LDQ W L +M+ IGN+ +N W N + T P E ++I++K++ F+ S + ++L S+V DV
Sbjct: 677 GNGRCADCGNPSSEWASINLGIIICIECSGIHRNLGSHISKVRGLELDQ--WPVEHLA-VMQAIGNDKANEMWEFGLLNGERKPT--PESSREEKERFIDRKYVQKAFLKPIASGEPVTSQLISAVLARDVM 803
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenG1A (gene:FBgn0028509 transcript:FBtr0080546) HSP 1 Score: 82.0333 bits (201), Expect = 2.045e-15 Identity = 49/157 (31.21%), Postives = 74/157 (47.13%), Query Frame = 3
Query: 720 FES--SELVNEWKIILSEAINIAFMGGENKILKQIYTNE------------SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFI 1148
FE+ SE +EW + + I + E+ KQ + + N C DCG PNPEW S+NL V++CI CSG+HR+L + S+++S LD W L +M IGN +N W N + E +++ K+ EF+
Sbjct: 662 FEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDD--WPSPHL-SVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFL 815
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenG1A (gene:FBgn0028509 transcript:FBtr0080547) HSP 1 Score: 82.0333 bits (201), Expect = 2.291e-15 Identity = 49/157 (31.21%), Postives = 74/157 (47.13%), Query Frame = 3
Query: 720 FES--SELVNEWKIILSEAINIAFMGGENKILKQIYTNE------------SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFI 1148
FE+ SE +EW + + I + E+ KQ + + N C DCG PNPEW S+NL V++CI CSG+HR+L + S+++S LD W L +M IGN +N W N + E +++ K+ EF+
Sbjct: 594 FEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDD--WPSPHL-SVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFL 747
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenG1A (gene:FBgn0028509 transcript:FBtr0080548) HSP 1 Score: 81.6481 bits (200), Expect = 2.334e-15 Identity = 49/157 (31.21%), Postives = 74/157 (47.13%), Query Frame = 3
Query: 720 FES--SELVNEWKIILSEAINIAFMGGENKILKQIYTNE------------SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFI 1148
FE+ SE +EW + + I + E+ KQ + + N C DCG PNPEW S+NL V++CI CSG+HR+L + S+++S LD W L +M IGN +N W N + E +++ K+ EF+
Sbjct: 430 FEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDD--WPSPHL-SVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFL 583
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenB1A (gene:FBgn0039056 transcript:FBtr0084368) HSP 1 Score: 77.0258 bits (188), Expect = 6.997e-14 Identity = 40/109 (36.70%), Postives = 62/109 (56.88%), Query Frame = 3
Query: 831 SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSN-LFWYKNKQNSSTIFPSDLSEIN-------SKYIEKKFI 1133
N C DC P P W SINL + LCI CSG+HRSL +S+++S LD WE S +++M ++GNE N ++ + + P++ EI +KY+E++F+
Sbjct: 392 GNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLD--AWE-SENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFV 497
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Match: CenB1A (gene:FBgn0039056 transcript:FBtr0084369) HSP 1 Score: 76.2554 bits (186), Expect = 8.808e-14 Identity = 40/109 (36.70%), Postives = 62/109 (56.88%), Query Frame = 3
Query: 831 SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSN-LFWYKNKQNSSTIFPSDLSEIN-------SKYIEKKFI 1133
N C DC P P W SINL + LCI CSG+HRSL +S+++S LD WE S +++M ++GNE N ++ + + P++ EI +KY+E++F+
Sbjct: 162 GNAYCCDCRSPEPRWASINLGITLCIECSGVHRSLGVHYSKVRSLTLD--AWE-SENVKVMMELGNEVVNRIYEARIGDDCGLKKPTEQCEIGVREAWIKAKYVERRFV 267
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: CR387919.1 (zmp:0000000660 [Source:NCBI gene;Acc:559690]) HSP 1 Score: 104.76 bits (260), Expect = 3.716e-22 Identity = 70/217 (32.26%), Postives = 111/217 (51.15%), Query Frame = 3
Query: 696 KSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINL-----SDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
KS F + ES +EW + E+I E +L++++ N+SN+ CADC P PEW SINLCV++C NC+G HR L S+++S LD IW + LIE+ ++GN+NSN W N + +E + +I +K+ ++ + + E+ L ++V DV TM L S + + L+A+ + Q LQ +FL
Sbjct: 586 KSFCFTV--ESEHERDEWIEAVQESIVETLCNYE--VLEKVWFNKSNRKCADCQAPEPEWASINLCVVICKNCAGQHRFLGPGISKVRSMKLDSSIWTNE-LIELFLEVGNKNSNSLWVANLPPEDELCKQSSTEQRASFIRRKYKKRKYKKVLNGLNTQEELNKALCAAVVLPDVLQTMALVFSGADVMCATGDPELSTPYLLAQKAGQRLQMEFL 797
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: CR387919.1 (zmp:0000000660 [Source:NCBI gene;Acc:559690]) HSP 1 Score: 104.76 bits (260), Expect = 3.716e-22 Identity = 70/217 (32.26%), Postives = 111/217 (51.15%), Query Frame = 3
Query: 696 KSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINL-----SDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
KS F + ES +EW + E+I E +L++++ N+SN+ CADC P PEW SINLCV++C NC+G HR L S+++S LD IW + LIE+ ++GN+NSN W N + +E + +I +K+ ++ + + E+ L ++V DV TM L S + + L+A+ + Q LQ +FL
Sbjct: 586 KSFCFTV--ESEHERDEWIEAVQESIVETLCNYE--VLEKVWFNKSNRKCADCQAPEPEWASINLCVVICKNCAGQHRFLGPGISKVRSMKLDSSIWTNE-LIELFLEVGNKNSNSLWVANLPPEDELCKQSSTEQRASFIRRKYKKRKYKKVLNGLNTQEELNKALCAAVVLPDVLQTMALVFSGADVMCATGDPELSTPYLLAQKAGQRLQMEFL 797
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: FO704810.1 (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like [Source:NCBI gene;Acc:100005008]) HSP 1 Score: 97.4413 bits (241), Expect = 5.136e-20 Identity = 68/250 (27.20%), Postives = 121/250 (48.40%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKN----KQNSSTIFPSDLSE-INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSNSIQDQTIIKDKIFKISYNNEEKLADLFS 1430
TF +SS+ + W L++ I A E + +++++ NK+CADCG NPEW S+NL V++C C+G HRS+ +S S+++ LD ++W + LI++ GN+ +N W N +Q S P +E I +KY + + + S + RLR V V T+ L S + +K + +A ++ Q LQ + L + ++ F+ + ++EE++ +L
Sbjct: 357 TFNFSADSSKEASAWLESLNDVIRNALSYSE--VALRLWSSPCNKVCADCGAANPEWASVNLLVVICEACAGAHRSMGSSRSKVRGLKLDDKVWTEP-LIQLFVLHGNKTANNVWGHNIPPTEQISPLASPDQRAEFILAKYHKGLYRKAHPLAASQKLLDQRLREVVCGPAVEETVSLLCSGAKVSCSSSDPELKSAIAVAESAGQALQTELL----------RHNEFVEAPDFEQTRHSEEQMEELHG 593
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:ZFIN;Acc:ZDB-GENE-091019-1]) HSP 1 Score: 97.4413 bits (241), Expect = 6.930e-20 Identity = 49/147 (33.33%), Postives = 81/147 (55.10%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
TF E+ +W L E+I A + ++ ++I++N SNK+CADC NP+W SINLCV++C NC+G HR L T S++QS LD +W + ++++ +GN+ +N FW S + E ++I K+ + +
Sbjct: 608 TFSFTAETDREKRDWMEALQESI--AETLSDYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRGLGTMVSKVQSLKLDTSVWSNE-IVQLFIMLGNDRANEFWAARLPVSEELDCDATPEQRREFISHKYKEGRY 751 HSP 2 Score: 72.4034 bits (176), Expect = 3.265e-12 Identity = 59/200 (29.50%), Postives = 96/200 (48.00%), Query Frame = 3
Query: 1953 GSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTAL 2552
G + L N PI+ +D I FI GL E I+RK GA +I L E K + + + DV LK++FR ++PI L + +A K+ + +L + + + +P +N L + LY +QK AD N+M +K+L+L A S+ D GE +I++DLID + +F + +T +
Sbjct: 1047 GGKGNTLKDQQLSRNDIPII---VDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMEEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPFWKEAAKIPLKTQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTD-GKGEHEVKIIEDLIDNYLYIFDVDEEHQTQI 1242
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Match: arap1a (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1a [Source:ZFIN;Acc:ZDB-GENE-030131-6226]) HSP 1 Score: 93.9745 bits (232), Expect = 6.132e-19 Identity = 48/150 (32.00%), Postives = 85/150 (56.67%), Query Frame = 3
Query: 696 KSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
++ +F + ES + W L+E ++ + + + + ++ ++N++CADC PEW S+NLCV+LC C+G HR+L + S+++S LD+R+W D LI + +GN +N FW N S + S SE K+I K+ + ++
Sbjct: 232 RAFSFMVDSESEK--QRWCESLTECVSRSLSC--DGVCESVWRVQANRICADCSSSMPEWASVNLCVLLCEKCAGAHRNLGQNISKVRSLKLDERVWTDD-LIRVFLMLGNGKANKFWGANIPPSERLSASANSEQRLKHITDKYKNGKY 376
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: ccn4 (cellular communication network factor 4 [Source:Xenbase;Acc:XB-GENE-484776]) HSP 1 Score: 108.997 bits (271), Expect = 1.277e-23 Identity = 85/273 (31.14%), Postives = 133/273 (48.72%), Query Frame = 3
Query: 708 FKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTI-FPSDLSE----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFLSVQ----PDLSNSIQDQTIIKDKIFKISYNNEEKLADLFSVSLLCTCISINIEELLTPAI 1490
F + ES EW + ++I A + ++ ++I+ NESN+ CADC P+P+W SI+L V++C NC+G HR+L ++ S++ S ILD IW + L+E+ +GNE N W N + + S++S+ I KY E +F F + E+ L +V D++ TM L S P + L+A+ S Q LQ +FL P++ Q I++ K N +AD V L IS+N TPA+
Sbjct: 131 FSLTAESEREKQEWTEEIQQSI--AETLADYEVAEKIWFNESNRSCADCRAPSPDWASISLGVVICKNCAGQHRALGSNISKVHSLILDTTIWSNE-LVELFIVVGNEKVNNIWEANLLPENMLHMDSNVSQRRLFITQKYKEGRFKKIYFPGFTQEELNQALCDAVTKDEILQTMILVFSGADTMCPTGDKVYNTPYLLAKMSGQRLQMEFLHHNRLSVPEMK---QWWCTIENNFLKYYENETAPVAD--GVIDLSEIISLN----FTPAV 391
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969]) HSP 1 Score: 89.3521 bits (220), Expect = 2.523e-17 Identity = 72/306 (23.53%), Postives = 140/306 (45.75%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSSYI-----------LIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
L+ F N ++ +P++ SI + N+F ++ + ++F + W I + + + + +R+ + + S Y+ ++ +DE +H E L + I VI + ++ + R+ + K+F ES EW L E I+ + + ++ ++I++N+SNK+CADC SINLCV++C C+G+HRSL T+ S++QS LD IW + ++++ +GN+ +N FW S + D E +I +K+ + ++
Sbjct: 287 LMYFSNDKELYPKGVIPLS-SIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMV------FPRLRLGCSSSCQRSGYLELKGYKSKIFAVLTTDELWIHKNEQLFK--MGIGMFVIGMHGCTIRDVRNKNFELVTMQKIFS------FTAESEREKKEWMEALLECISESL--SDYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSNE-IVQLFIILGNDKANRFWAAKLLPSEMLHTDDPVERRRNFITQKYREGKY 568 HSP 2 Score: 72.7886 bits (177), Expect = 3.293e-12 Identity = 56/180 (31.11%), Postives = 92/180 (51.11%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
L N PI+ +D I F+ GL+ E I+RK GA +I L + K + + + + DV LK++FR ++PI T L + +A S +L + ++ +P +N L + LY +QK AD N+M +K+LAL A S+ D GE ++++D+ID + +VF
Sbjct: 785 QLSRNDIPII---VDSCIAFLTQYGLRHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRISDNFIEDVTDVLKRFFRELDDPIFTTELHPQWKEAADNPEKSKRLEKYMELINHLPRVNRATLAALIGHLYRVQKCADLNQMCTKNLALLFAPSLFQTD-GKGEHEVKVMEDIIDNYASVF 960
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969]) HSP 1 Score: 89.3521 bits (220), Expect = 2.673e-17 Identity = 72/306 (23.53%), Postives = 141/306 (46.08%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSSYI-----------LIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
L+ F N ++ +P++ SI + N+F ++ + ++F + W I + + + + +R+ + + S Y+ ++ +DE +H E L + I VI + ++ + R+ + K+F + ES EW L E I+ + + ++ ++I++N+SNK+CADC SINLCV++C C+G+HRSL T+ S++QS LD IW + ++++ +GN+ +N FW S + D E +I +K+ + ++
Sbjct: 152 LMYFSNDKELYPKGVIPLS-SIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMV------FPRLRLGCSSSCQRSGYLELKGYKSKIFAVLTTDELWIHKNEQLFK--MGIGMFVIGMHGCTIRDVRNKNFELVTMQKIFSFTA------ESEREKKEWMEALLECISESL--SDYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSNE-IVQLFIILGNDKANRFWAAKLLPSEMLHTDDPVERRRNFITQKYREGKY 433
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: itgav (integrin subunit alpha V [Source:Xenbase;Acc:XB-GENE-488969]) HSP 1 Score: 89.3521 bits (220), Expect = 2.818e-17 Identity = 72/306 (23.53%), Postives = 141/306 (46.08%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSSYI-----------LIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
L+ F N ++ +P++ SI + N+F ++ + ++F + W I + + + + +R+ + + S Y+ ++ +DE +H E L + I VI + ++ + R+ + K+F + ES EW L E I+ + + ++ ++I++N+SNK+CADC SINLCV++C C+G+HRSL T+ S++QS LD IW + ++++ +GN+ +N FW S + D E +I +K+ + ++
Sbjct: 335 LMYFSNDKELYPKGVIPLS-SIEMARSTKENKFEVVTKHRTFVFRAENEVQRNEWCATIQNRVKEHRMV------FPRLRLGCSSSCQRSGYLELKGYKSKIFAVLTTDELWIHKNEQLFK--MGIGMFVIGMHGCTIRDVRNKNFELVTMQKIFSFTA------ESEREKKEWMEALLECISESL--SDYEVAEKIWSNKSNKICADCR------ASINLCVVICKQCAGVHRSLGTNISKVQSLKLDTSIWSNE-IVQLFIILGNDKANRFWAAKLLPSEMLHTDDPVERRRNFITQKYREGKY 616 HSP 2 Score: 70.0922 bits (170), Expect = 2.159e-11 Identity = 56/180 (31.11%), Postives = 93/180 (51.67%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
L N PI+ +D I F+ GL+ E I+RK GA +I L + K + + + + DV LK++FR ++PI T L + +A + S +L + ++ +P +N L + LY +QK AD N+M +K+LAL A S+ D GE ++++D+ID + +VF
Sbjct: 913 QLSRNDIPII---VDSCIAFLTQYGLRHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRISDNFIEDVTDVLKRFFRELDDPIFTTELHPQWKEAAE---KSKRLEKYMELINHLPRVNRATLAALIGHLYRVQKCADLNQMCTKNLALLFAPSLFQTD-GKGEHEVKVMEDIIDNYASVF 1085
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Match: ikzf2 (IKAROS family zinc finger 2 [Source:Xenbase;Acc:XB-GENE-1013632]) HSP 1 Score: 88.5817 bits (218), Expect = 3.002e-17 Identity = 63/188 (33.51%), Postives = 96/188 (51.06%), Query Frame = 3
Query: 729 SELVNEWKIILS----EAINIAFMG----GENKILKQ--------IYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSK--YIEKKFIDTEFINLS--DNEIK-NRLRSSVATDDVFLTMKLY 1229
+E EW +L EA+N AF G GEN I+++ I N +C DCG +P W+S NL ++ CI CSG+HR L +SRIQS LD + S L+ + K IGN N ++ PS S++N++ YI K+I+ ++ DN K + L +V + D+F ++L+
Sbjct: 350 AEDETEWMSVLQNSKEEALNNAFKGDHSAGENNIVQELTKEIISDIQRMPGNDVCCDCGASDPTWLSTNLGILTCIECSGIHRELGVHYSRIQSLTLD--VLGTSELL-LAKNIGNSGFNELMEACLPADDSVKPSPCSDMNARKDYITTKYIERKYARRKYHDNASKLHGLCDAVKSRDIFTLVQLH 534
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:MGI Symbol;Acc:MGI:2684416]) HSP 1 Score: 115.161 bits (287), Expect = 2.627e-25 Identity = 73/214 (34.11%), Postives = 108/214 (50.47%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
+F +S EW I + +IA + ++ ++I+ NESN+ CADC P+P+W SINLCV++C C+G HRSL S+++S +D IW + LIE+ IGN+ +N FW N Q + E I KY E KF T +L+ E+ L ++V DV TM L S + L+A+ + Q LQ +FL
Sbjct: 654 SFSFTADSEREKQEW--IEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNE-LIELFIVIGNKRANDFWAGNLQKDEELQVDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 864 HSP 2 Score: 56.9954 bits (136), Expect = 1.606e-7 Identity = 34/142 (23.94%), Postives = 65/142 (45.77%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMD 2408
L N PI+ N I F+ GL ++I++K G I+ L E +K + + + DV LK + ++ ++T L+ + A ++ + ++ + S+P +N L +E LY +QK ++ N M+
Sbjct: 1120 QLCKNDVPIIVN---SCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMN 1258
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:MGI Symbol;Acc:MGI:1916960]) HSP 1 Score: 105.145 bits (261), Expect = 2.484e-22 Identity = 85/374 (22.73%), Postives = 167/374 (44.65%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKN-WVNKINTLLLNYED-LQLNYFKYAEVRIDSNEASNVSS----------YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYH---SIKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
L F ++ D S + +P+ R+ I + +F ++ N + F +++ + +N W+ + ++ + +L+ VR S + S Y+ + D+ + +Y+NL E I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P+W SINLCV++C C+G HR L S+++S +D+++W ++ LI++ +GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L + L +A + Q LQ +FL
Sbjct: 111 LRYFDSNKDAYSKRFVPVACICRVAPIGD-QKFEVITNNRTFAF-RAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVR-GSEQPDRAGSLELRGFKNKLYVAVTGDK--VQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEA-LIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPAAPTPLALAEQAGQTLQMEFL 470 HSP 2 Score: 55.4546 bits (132), Expect = 4.915e-7 Identity = 40/171 (23.39%), Postives = 88/171 (51.46%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKE 2540
+ + +I GL SE I+RK G K L + + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M++ +LA+ ++ D + ++++DLI+++ VF +E
Sbjct: 730 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTD-GQDYKAGKVVEDLINHYVVVFSVDEEE 899
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:MGI Symbol;Acc:MGI:1916960]) HSP 1 Score: 105.531 bits (262), Expect = 2.544e-22 Identity = 87/375 (23.20%), Postives = 168/375 (44.80%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKN-WVNKINTLLLNYED-LQLNYFKYAEVRIDSNEASNVSS----------YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
L F ++ D S + +P+ R+ I + +F ++ N + F +++ + +N W+ + ++ + +L+ VR S + S Y+ + D+ + +Y+NL E I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P+W SINLCV++C C+G HR L S+++S +D+++W ++ LI++ +GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D L +A + Q LQ +FL
Sbjct: 359 LRYFDSNKDAYSKRFVPVACICRVAPIGD-QKFEVITNNRTFAF-RAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVR-GSEQPDRAGSLELRGFKNKLYVAVTGDK--VQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEA-LIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPA-APTPLALAEQAGQTLQMEFL 718 HSP 2 Score: 54.6842 bits (130), Expect = 7.992e-7 Identity = 39/165 (23.64%), Postives = 86/165 (52.12%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+ + +I GL SE I+RK G K L + + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M++ +LA+ ++ D + ++++DLI+++ VF
Sbjct: 978 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTD-GQDYKAGKVVEDLINHYVVVF 1141
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:MGI Symbol;Acc:MGI:1916960]) HSP 1 Score: 105.145 bits (261), Expect = 2.779e-22 Identity = 87/375 (23.20%), Postives = 168/375 (44.80%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKN-WVNKINTLLLNYED-LQLNYFKYAEVRIDSNEASNVSS----------YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
L F ++ D S + +P+ R+ I + +F ++ N + F +++ + +N W+ + ++ + +L+ VR S + S Y+ + D+ + +Y+NL E I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P+W SINLCV++C C+G HR L S+++S +D+++W ++ LI++ +GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D L +A + Q LQ +FL
Sbjct: 359 LRYFDSNKDAYSKRFVPVACICRVAPIGD-QKFEVITNNRTFAF-RAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVR-GSEQPDRAGSLELRGFKNKLYVAVTGDK--VQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEA-LIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPA-APTPLALAEQAGQTLQMEFL 718 HSP 2 Score: 54.6842 bits (130), Expect = 8.070e-7 Identity = 39/165 (23.64%), Postives = 86/165 (52.12%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+ + +I GL SE I+RK G K L + + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M++ +LA+ ++ D + ++++DLI+++ VF
Sbjct: 978 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTD-GQDYKAGKVVEDLINHYVVVF 1141
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Match: Arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:MGI Symbol;Acc:MGI:2147274]) HSP 1 Score: 92.4337 bits (228), Expect = 2.496e-18 Identity = 38/141 (26.95%), Postives = 73/141 (51.77%), Query Frame = 3
Query: 708 FKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKF 1130
F ES W L EA+ + ++ +++++N +N+ CADC P+W ++NL V++C C+G HR+L + S++QS LD +W + ++++ +GN+ +N FW + P ++I +K+
Sbjct: 378 FSFTAESGGARQSWAAALQEAVTETL--SDYEVAEKVWSNPANRHCADCRASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNE-IVQLFIVLGNDRANCFWAGALPPGEGLHPDSAPGPRGEFISRKY 515 HSP 2 Score: 75.8702 bits (185), Expect = 2.738e-13 Identity = 51/168 (30.36%), Postives = 90/168 (53.57%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGA-VRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+D I+F+ GL+ E ++RK GA R + L E + + P + V DV LK++FR ++P+ + L + +A +L + +L + + +S +P +N + L + LY +QK A N+M +++LAL A S+ D GE +L++LID + +VF
Sbjct: 841 VDACISFVTQHGLRLEGVYRKGGARARSLRLLAEF-RRDARSVKLRPREHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCASLNQMCTRNLALLFAPSVFQTD-GRGEHEVRVLQELIDGYISVF 1006
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8WZ64|ARAP2_HUMAN (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARAP2 PE=1 SV=3) HSP 1 Score: 115.161 bits (287), Expect = 2.124e-24 Identity = 72/214 (33.64%), Postives = 109/214 (50.93%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
+F E+ + +W I + +IA + ++ ++I+ NESN+ CADC P+P+W SINLCV++C C+G HRSL S+++S +D IW + LIE+ IGN+ +N FW N Q + E I KY E KF T +L+ E+ L ++V DV TM L S + L+A+ + Q LQ +FL
Sbjct: 656 SFSFTAETEKEKQDW--IEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNE-LIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 866 HSP 2 Score: 59.3066 bits (142), Expect = 2.217e-7 Identity = 35/142 (24.65%), Postives = 67/142 (47.18%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMD 2408
L N PI+ N I F+ GL ++I++K G I+ L E +K F + + + DV + LK + ++ ++T L+ + A ++ ++ + + S+P +N L +E LY +QK ++ N M+
Sbjct: 1122 QLSKNDVPIIVN---SCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN 1260
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8BZ05|ARAP2_MOUSE (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 OS=Mus musculus OX=10090 GN=Arap2 PE=1 SV=2) HSP 1 Score: 113.235 bits (282), Expect = 8.262e-24 Identity = 72/214 (33.64%), Postives = 107/214 (50.00%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
+F +S EW I + +IA + ++ ++I+ NESN+ CADC P+P+W SINLCV++C C+G HRSL +++S +D IW + LIE+ IGN+ +N FW N Q + E I KY E KF T +L+ E+ L ++V DV TM L S + L+A+ + Q LQ +FL
Sbjct: 654 SFSFTADSEREKQEW--IEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDCKVRSLKMDASIWSNE-LIELFIVIGNKRANDFWAGNLQKDEELQVDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFL 864 HSP 2 Score: 56.9954 bits (136), Expect = 1.124e-6 Identity = 34/142 (23.94%), Postives = 65/142 (45.77%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMD 2408
L N PI+ N I F+ GL ++I++K G I+ L E +K + + + DV LK + ++ ++T L+ + A ++ + ++ + S+P +N L +E LY +QK ++ N M+
Sbjct: 1120 QLCKNDVPIIVN---SCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMN 1258
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q96P48|ARAP1_HUMAN (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3) HSP 1 Score: 112.849 bits (281), Expect = 8.579e-24 Identity = 73/272 (26.84%), Postives = 131/272 (48.16%), Query Frame = 3
Query: 534 YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
Y+ + D+ + +Y+NL E+ I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P P+W SINLCV++C C+G HR L S+++S +D+++W ++ LIE+ ++GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D E L +A + Q LQ +FL
Sbjct: 457 YVAVVGDK--VQLYKNLEEYHLGIGITFIDMSVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTET-LIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPE-APTPLALAEQAGQTLQMEFL 716 HSP 2 Score: 55.4546 bits (132), Expect = 3.312e-6 Identity = 40/165 (24.24%), Postives = 84/165 (50.91%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+ + +I GL SE I+RK G K L E + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M+ +LA+ ++ D + +++DLI+++ VF
Sbjct: 976 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTD-GQDYKAGRVVEDLINHYVVVF 1139
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q4LDD4|ARAP1_MOUSE (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Mus musculus OX=10090 GN=Arap1 PE=1 SV=2) HSP 1 Score: 105.145 bits (261), Expect = 1.944e-21 Identity = 87/375 (23.20%), Postives = 168/375 (44.80%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKN-WVNKINTLLLNYED-LQLNYFKYAEVRIDSNEASNVSS----------YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLS-----EINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFL 1322
L F ++ D S + +P+ R+ I + +F ++ N + F +++ + +N W+ + ++ + +L+ VR S + S Y+ + D+ + +Y+NL E I I++ +++ S ++F S + E + + + ++EA++ +++ ++I+ N+ CADCG P+W SINLCV++C C+G HR L S+++S +D+++W ++ LI++ +GN N FW N S + PS + +KY E K+ + + E+ L ++V T D+ T L F D L +A + Q LQ +FL
Sbjct: 359 LRYFDSNKDAYSKRFVPVACICRVAPIGD-QKFEVITNNRTFAF-RAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVR-GSEQPDRAGSLELRGFKNKLYVAVTGDK--VQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPYRIF--SFSADSELEKEQWLEAMQGAIAEALST------SEVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEA-LIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPA-APTPLALAEQAGQTLQMEFL 718 HSP 2 Score: 54.6842 bits (130), Expect = 5.645e-6 Identity = 39/165 (23.64%), Postives = 86/165 (52.12%), Query Frame = 3
Query: 2028 KMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+ + +I GL SE I+RK G K L + + + + +V+DV+S LK++ R + + T + + +A ++E+ K+++ + +P +N ++ + LY +Q F+D N+M++ +LA+ ++ D + ++++DLI+++ VF
Sbjct: 978 RCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTD-GQDYKAGKVVEDLINHYVVVF 1141
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Match: sp|Q8WWN8|ARAP3_HUMAN (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ARAP3 PE=1 SV=1) HSP 1 Score: 97.0561 bits (240), Expect = 7.465e-19 Identity = 40/141 (28.37%), Postives = 74/141 (52.48%), Query Frame = 3
Query: 708 FKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKF 1130
F ES W L EA+ + ++ ++I++N +N+ CADCG P+W ++NL V++C C+G HR+L + S++QS LD +W + ++++ +GN+ +N FW + P ++I +K+
Sbjct: 461 FSFTAESGGARQSWAAALQEAVTETLS--DYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNE-IVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKY 598 HSP 2 Score: 74.7146 bits (182), Expect = 4.419e-12 Identity = 50/168 (29.76%), Postives = 89/168 (52.98%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGA-VRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+D I+F+ GL+ E ++RK GA R + L E + + P + V DV LK++FR ++P+ + L + +A +L + +L + + + +P +N + L + LY +QK A N+M +++LAL A S+ D GE +L++LID + +VF
Sbjct: 923 VDACISFVTQHGLRLEGVYRKGGARARSLRLLAEF-RRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTD-GRGEHEVRVLQELIDGYISVF 1088
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: G1KLB4 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 OS=Anolis carolinensis OX=28377 GN=ARAP3 PE=4 SV=1) HSP 1 Score: 147.902 bits (372), Expect = 5.276e-32 Identity = 167/656 (25.46%), Postives = 295/656 (44.97%), Query Frame = 3
Query: 708 FKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFLS--------VQPDL-------SNSIQDQTIIKDK---------------IFKISYNNEEKLADLFSVSLLCTCISINIEELLTPAIYINICCIYYTDIELIWYDSTNESLVITLFNNCQFFKNPKSRTSKKY-PITVHRLSFFDQSNVIKQFQLDLFKLLMPNHFVELTF---NSNLF------------MNLEVKLNENNTIKCKSHVDEQGIIFYFPIAIIFDLKNSTKIQLIDDKIISIKFNNDQIEIVTNNFGSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
F ES EW L +I E + ++I++N++N+LCADC P+P+W S+NLCV++C +C+G HRSL +S S++QS LD IW + ++++ +GNE N FW S ++P +E I KY ++ S +I L S+V+ + TM L+ + ++E + L + N ++E LS QP + ++ T+IK +F + + E LA + V + IS+ + L P IN I++T +EL + + L ++ Q + S K + P++ H L ++ V K L +L PN +++ F S+LF +NL +L E + + +++ ++ + F L+ ++++ F+ + I + G N + + L + PI+ N I FI GL+ E I+RK GA +I L E + + + + + DV LK++FR +P+ T L + +A + S +L + + ++ +P +N + L + LY +QK AD N+M +K+LAL A S+ D GE ++++DLID + +F
Sbjct: 467 FSFVAESEREKREWMEALQNSIAETLYDYE--VAEKIWSNKANRLCADCHAPSPDWASVNLCVVICKHCAGQHRSLGSSISKVQSLKLDTSIWSNE-MVQLFIMLGNEQVNKFWETQLPPSEALYPDANAEQRQNFITCKYRYGRYCMPHPHYSSQEDILQALCSAVSGPGLLKTMLLFFATTMETENEVTEHPKLASSCGNLGVEE--LSPEGVYNEVTQPIAHSGYLYKAPAVTKLTVIKKSREEFQRVWCSLEKCFLFYETDKSSEPLAKIEMVDV----ISLGVSSL--PWEIINR--IHFT-LELYLSNERVQQLEADGPDSLQSW---ASAIGKWFTPLSCHCLLGYEFQRVGK---LCYKSMLNPNQWLQGFFILQKSHLFICPGEEGATEDSINLR-QLQELSVVPLPEGAEKKEMLVLVEMGRTFCLQGTSRLD----------FSTWCMAIQASASGQGNALRDQ-QLSRSGIPIIVN---SCIAFITQYGLQHEGIYRKNGAKSRIKLLMEDFRRDARNVKLRISDNFIEDVTDVLKRFFRELEDPVFTTYLHPQWKEAAGILQKSQRLEKYKELINHLPHLNRRTLAALIGHLYRVQKCADLNQMTTKNLALLFAPSLFQTD-GKGEHEVKVMEDLIDNYVYIF 1086
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A3P8XRP3 (Uncharacterized protein OS=Esox lucius OX=8010 PE=4 SV=1) HSP 1 Score: 134.035 bits (336), Expect = 5.278e-28 Identity = 100/397 (25.19%), Postives = 184/397 (46.35%), Query Frame = 3
Query: 270 FKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKIN-TLLLNYEDLQLNYFKYAEVRIDSNEASNVSS-------------YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFLSVQPDL---SNSIQDQTIIKDKI 1382
F N ++ S KR+ SI +F ++ N +LF + ++ + WV+ + T+ + + +++++ +++ N ++S Y++I +D L Y + EH Q + I + ++ ++ S + TF ES + +W L + + N++ ++I+ E+N+ CADCG PNP+W S+NLCV+LC C+G+HR L S S++ S D+ +W DS LI++ + +GN+ NLFW N S + PS SE + +KY + K+ + + E+ L +++ T DV T+ L + D E + + A++ Q LQ +FL+ + DQ +IK +
Sbjct: 30 FDNEKEVYS-KRIIAIASITHVLNVGGQKFAVVTRNRTFLFRSENNTVREEWVSVLQATVQQHRKRVEMSFMNVSDMSGQHNGGVSISKQGYLEVDGLRSKVYVVICADRVFL--YRSTEEHNQGVGITSIEMNMVTVTSTDKRSFNITTFCR------TFSFMAESEQQREQWVEALKACVGRSL--SSNRVAQKIWAEEANQRCADCGAPNPDWASVNLCVVLCKCCAGVHRGLGQSVSKVCSLRTDEHLWTDS-LIQVFRLLGNDRVNLFWAANLPPSEALCPSSDSEERLQFVTAKYCQGKYRNYHALFAKQEELNKALCNNIKTSDVLETLALVFCGADVNSYTGDPELPSPVSM-AQHYGQTLQVEFLTRNHSTEIPGSRAGDQPVIKAAL 413
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A4W5P1Z8 (Uncharacterized protein OS=Hucho hucho OX=62062 PE=4 SV=1) HSP 1 Score: 130.568 bits (327), Expect = 7.311e-27 Identity = 99/388 (25.52%), Postives = 189/388 (48.71%), Query Frame = 3
Query: 270 FKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLL---LNYEDLQLNYFKYAEVRIDSN----------EASNVSS--YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFIN----LSDNEIKNR-LRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSNSIQDQ 1361
F+N ++ S + + I + + +F ++ N +LF + ++ + WV+ + + N ++ L F + + DS E + + S Y++I +D L Y N E++Q + I + +++++ S + TF ES++L ++W L + ++ + + + ++I+ E+N+ CADCG P+P+W S+NLCV+LC C+G+HR L S S+++S +D+++W D+ LI++ +GN NLFW N S + PS SE+ +++ K+ ++ E N+ L S+V TDDV T+ L + D E + + A++ Q LQ +FL+ + S+ +Q
Sbjct: 30 FQNEKEVYSKRIIAILSVTEVLNV-GEQKFEVVTRNRTFLFRAENNTVREEWVSVLKETIQQRRNGMEMSLMNFSFTSGQRDSGVSLISKQGYLEMNGLRSKVYVVICADRVFL--YGNAEEYSQGVGITYIEMNVGTVKSTDKRSFNLTTFYR------TFSFLAESAQLRDQWVEALQDCVSRSL--SSDVVAQKIWAVEANQRCADCGAPHPDWASVNLCVVLCKCCAGVHRGLGQSVSKVRSLRMDEKVWTDN-LIQVF-LVGNNRVNLFWAANMPPSEALHPSSDSEMRQRFVSAKYCQGKYRRYHALFGQQEALNKALCSTVQTDDVLETLSLVFCGADVNCYTGDPELPSPVSM-AQHYGQILQVEFLTHNHNTGRSLINQ 403 HSP 2 Score: 78.1814 bits (191), Expect = 1.093e-10 Identity = 50/193 (25.91%), Postives = 92/193 (47.67%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIR 2600
+D+ +++I GLKSE I+R+ G KI AL + + V+DVA+ LK++ R E + +L + S +++Q + + S+P +N L + LY +Q FADEN+M+ +LA+ ++ D ++++DLI ++ +F S A + I V E ++ +
Sbjct: 636 VDRCMSYITQHGLKSEGIYRRCGVNSKIAALLFFLRHDARQVRLSEGERQVDDVANVLKRFLREVGEGVFNGHQASLPWLHTTSDEMSERVSQYQALLHSLPRVNRATLGAVINHLYCVQCFADENQMNMHNLAIVFGPTLFQMDGTDNS-PGQVVEDLIQNYQDIFNVSVSPLPAPLSQISQEVSAEELVCK 827
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A060WR07 (Uncharacterized protein OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00013490001 PE=4 SV=1) HSP 1 Score: 124.405 bits (311), Expect = 9.375e-27 Identity = 80/273 (29.30%), Postives = 141/273 (51.65%), Query Frame = 3
Query: 534 YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFIN----LSDNEIKNR-LRSSVATDDVFLTMKLYHSIK----FPYDSEFIKEILLIARNSNQYLQEKFLS 1325
Y++I +D L Y N EH+Q + I + +++++ S + TF ES++ ++W L + ++ + + + ++I+ E+N+ CADCG P+P+W S+NLCV+LC C+G+HR L S S+++S +D+++W D+ LI++ +GN NLFW N S + PS SE +++ K+ ++ E N+ L S+V TDDV T+ L + D E + +A++ Q LQ +FL+
Sbjct: 61 YVVICADRVFL--YGNAEEHSQGVGITYIEMNVGTVKSTDKRSFNLTTFYR------TFSFLAESAQQRDQWVEALQDCVSRSL--SSDVVAQKIWAVEANQRCADCGAPHPDWASVNLCVVLCKCCAGVHRGLGQSVSKVRSLRMDEKVWTDN-LIQVF-LLGNNRVNLFWAANTPPSEALQPSSDSEKRQRFVSAKYCQGKYRRYHALFGQQEALNKALCSTVQTDDVLETLSLVFCGADVNCYTGDPELPSPV-SVAQHYGQILQVEFLT 320
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Match: A0A210PGH0 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12956 PE=4 SV=1) HSP 1 Score: 129.798 bits (325), Expect = 2.169e-26 Identity = 80/223 (35.87%), Postives = 124/223 (55.61%), Query Frame = 3
Query: 681 LKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSK-YIEKKFIDTEFIN---LSDNE--IKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
L+L F + FE+ E W++ + E+I A G+N IL+QI N SN CADC P+P W SIN+ ++LC C+G+HR + S+++S +D +W S LIE+MK+IGN N+NLFW K+ + S F D+ K ++E K+ + ++I+ LSDN+ + L + +T D+ LTM L S +K + IA+ + Q LQ + L
Sbjct: 1008 LRLATHYTQFVLAFETYEDCVTWRMAMEESIADAL--GDNTILEQIKKNPSNHECADCSAPDPHWASINMGIVLCKQCAGIHRKFDLNVSKVRSLRMDTSVWSPS-LIEMMKQIGNHNANLFWEKHLRAKSG-FNQDMESAQRKQHLENKYENRKYIDKHPLSDNKPALNEELLKAASTADILLTMMLVFSGADVKVIKPGTQEETAFSIAKAAGQRLQMELL 1226 HSP 2 Score: 71.633 bits (174), Expect = 1.387e-8 Identity = 36/128 (28.12%), Postives = 69/128 (53.91%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKM 2405
+DK + FI GL+ E I+R K++ L K + ++ + V++VA+ LK++FR+ +P++T L+N + + K T +KL + + +P ++ + LR+ V L + ++ ENKM
Sbjct: 1505 VDKCLKFIDDHGLQEEGIYRLAATNSKVDTLLATFAKDAHAVKLELGTHTVHEVANALKRFFRNLKDPLLTSHLYNTWIEKSKTTMTQTKLDWYHYYIRELPTVHSRTLRRLVIHLAKLSGYSVENKM 1632
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:NCBI gene;Acc:103028333]) HSP 1 Score: 109.383 bits (272), Expect = 1.288e-23 Identity = 60/173 (34.68%), Postives = 96/173 (55.49%), Query Frame = 3
Query: 723 ESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKL 1226
E+ +L ++W + +I A E + ++I+ N+ CADCG P PEW +INLCV+ C C+G HRSL S S+++S +D+++W + LI++ + +GNE +N FW N S + SE I +KY E K+ + + EI N L +V ++DV T+ L
Sbjct: 663 ETDQLKDQWVEAMRNSIAEALSNYE--VAEKIWAEPDNQKCADCGAPKPEWAAINLCVVFCKRCAGEHRSLGPSISKVRSLKMDKKVWTNE-LIQLFRVLGNERANQFWAANVPPSEALSVCSSSEERRRFITAKYREGKYRRYHPLFGNQKEINNALCINVQSNDVCETLAL 832 HSP 2 Score: 66.6254 bits (161), Expect = 1.578e-10 Identity = 36/129 (27.91%), Postives = 67/129 (51.94%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMD 2408
+++ I +I GL SE I+RK G KI AL E ++ ++ V+DV++ LK++FR E + N + + S +++ + +++P +N LR V LY +Q+F++ N+M+
Sbjct: 1121 VERCIHYITQYGLTSEGIYRKSGVNSKIAALLEAFRRNARSVWLKEAEQQVDDVSNVLKRFFRDIEEGLFGQHAQNWLTTTA-VSDESKRISHYQLLFNNLPRVNKATLRTLVNHLYCVQRFSEMNQMN 1248
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:ZFIN;Acc:ZDB-GENE-091019-1]) HSP 1 Score: 100.908 bits (250), Expect = 4.360e-21 Identity = 48/115 (41.74%), Postives = 72/115 (62.61%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW 1049
TF ES EW L E+I A + ++ ++I++N SNK+CADC NP+W SINLCV++C NC+G HRSL T S++QS LD +W + ++++ +GN+ +N FW
Sbjct: 544 TFSFTAESDRDKREWMEALQESI--AETLSDYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRSLGTMVSKVQSLKLDTSVWSNE-IVQLFIMLGNDRANEFW 655 HSP 2 Score: 74.3294 bits (181), Expect = 7.082e-13 Identity = 60/190 (31.58%), Postives = 93/190 (48.95%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTAL 2552
L N PI+ +D I FI GL E I+RK GA +I L + K + + + DV LK++FR ++PI L + DA K N +L + + + +P +N L + LY +QK AD N+M +K+L+L A S+ D GE +I++DLID + VF + +T +
Sbjct: 992 QLSRNDIPII---VDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPYWKDAAKTSNKMQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTD-GKGEHEVKIVEDLIDNYLYVFDIDEEHKTQI 1177
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:ZFIN;Acc:ZDB-GENE-091019-1]) HSP 1 Score: 100.908 bits (250), Expect = 4.653e-21 Identity = 48/115 (41.74%), Postives = 72/115 (62.61%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW 1049
TF ES EW L E+I A + ++ ++I++N SNK+CADC NP+W SINLCV++C NC+G HRSL T S++QS LD +W + ++++ +GN+ +N FW
Sbjct: 649 TFSFTAESDRDKREWMEALQESI--AETLSDYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRSLGTMVSKVQSLKLDTSVWSNE-IVQLFIMLGNDRANEFW 760 HSP 2 Score: 74.3294 bits (181), Expect = 7.370e-13 Identity = 60/190 (31.58%), Postives = 93/190 (48.95%), Query Frame = 3
Query: 1983 NLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTAL 2552
L N PI+ +D I FI GL E I+RK GA +I L + K + + + DV LK++FR ++PI L + DA K N +L + + + +P +N L + LY +QK AD N+M +K+L+L A S+ D GE +I++DLID + VF + +T +
Sbjct: 1097 QLSRNDIPII---VDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMDEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPYWKDAAKTSNKMQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTD-GKGEHEVKIVEDLIDNYLYVFDIDEEHKTQI 1282
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: ENSAMXT00000000841.2 (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like [Source:NCBI gene;Acc:103047121]) HSP 1 Score: 98.5969 bits (244), Expect = 1.672e-20 Identity = 69/211 (32.70%), Postives = 102/211 (48.34%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
+F +SS+ W L+E I A E + +++ + NK+CADCG NPEW SINL V++C C+G+HRS+ TS S+++S LD +IW + LI++ GN+ SN W N + I P E I +KY + T + + + RL V DV T+ L S + IA N+ Q LQ + L
Sbjct: 335 SFNFSADSSKDQTTWLNQLNEVIRSALSCSE--VALRLWASPWNKVCADCGSSNPEWASINLLVVICEACAGVHRSIGTSRSKVRSLKLDSKIWTEP-LIKLFIIYGNKASNNVWGHNVPAAEQILPDAGQEERDAFIKAKYCSGLYRKTHPLISNQTLLNQRLCEVVCGVDVEETLCLLCSGAKVLTDPQSPSAISIAENAGQALQTELL 542
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Match: ENSAMXT00000019510.2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:NCBI gene;Acc:103040621]) HSP 1 Score: 92.4337 bits (228), Expect = 1.920e-18 Identity = 69/215 (32.09%), Postives = 107/215 (49.77%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKN----KQNSSTIFPSDLSEINSKYIEKKFIDTEFINLSDNEIKNR-LRSSVATDDVFLTMKLYHS----IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
+F ES EW + E+I E + ++++ N+SN+ CADC PNPEW SINL V++C C+G HR L + S+++S LD IW + L+E+ ++GNEN+N FW N ++ P + + + ++ L + E N+ L ++V DV +TM L S + D E LL A+ Q LQ +FL
Sbjct: 592 SFCFTAESEREREEWIEAVQESIVETLSNYE--VAEKVWFNQSNRNCADCRAPNPEWASINLGVVICKLCAGQHRFLGSGISQVRSLKLDSSIWTNE-LVELFLEVGNENANKFWAFNLPLEEELHMGATPEQRATFHRRKYRERKYRRVLGGLHNQEGLNQALCAAVLQSDVLVTMALVFSGADVMCATGDPEHSTPYLL-AQKGGQRLQMEFL 802
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007633.1 (pep scaffold:Pmarinus_7.0:GL488501:137984:146551:-1 gene:ENSPMAG00000006898.1 transcript:ENSPMAT00000007633.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 106.301 bits (264), Expect = 5.127e-24 Identity = 60/181 (33.15%), Postives = 95/181 (52.49%), Query Frame = 3
Query: 804 ILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINLSD-----NEIKNRLRSSVATDDVFLTMKLYH---SIKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
I +I+ +N+LCADCG P W SINLCV++C C+G HR+L + S+++S +D++IW D LIE+ +IGNE N FW N S I P+ + +++ K+ ++ + E+ L S+V T DV +M L + + + LL+A + Q LQ + L
Sbjct: 210 IADRIWALPANRLCADCGAAKPAWASINLCVVICKLCAGQHRALGPNISKVRSLKMDKKIWTDD-LIELFVQIGNERVNEFWAANVPPSEEIDPASMPNERREFVVAKYRSGKYRRYHEFFGDQAELNRALCSAVVTSDVLESMALVYCGADVTGAPGCSPDDDPLLLAEQAGQKLQLQML 389
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000232.1 (pep scaffold:Pmarinus_7.0:GL480628:15362:26221:1 gene:ENSPMAG00000000209.1 transcript:ENSPMAT00000000232.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 102.449 bits (254), Expect = 1.588e-23 Identity = 49/147 (33.33%), Postives = 83/147 (56.46%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
TF E+ +EW + ++I + + KQI+ NE N+ CADCG P+W S+NLCV++C C+G HR+L + S+++S +D+ IW + LIE+ +++GN N FW + S + PS +E +Y+ K+ + +
Sbjct: 185 TFSFMAENERERDEWLETMRDSIATSL--SHLDVAKQIWANEHNRRCADCGAAWPDWASVNLCVVICKRCAGEHRNLGQTVSKVRSLKMDKNIWTKN-LIELFQELGNAQVNKFWAASVPPSEAVDPSSEAERRREYVFAKYREGRY 328
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: acap3b (ArfGAP with coiled-coil, ankyrin repeat and PH domains 3b [Source:ZFIN;Acc:ZDB-GENE-070209-274]) HSP 1 Score: 84.7297 bits (208), Expect = 2.191e-17 Identity = 44/132 (33.33%), Postives = 71/132 (53.79%), Query Frame = 3
Query: 762 SEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSK--YIEKKFIDTEFIN 1151
S+A + G + +L ++ N+ C DCG P+P W SINL + LCI CSG+HRSL S+++S LD WE L+++M ++GN N + + + P+ S K +I K++D +F+
Sbjct: 55 SDARDRGARGCSDNVLARVQAIRGNERCCDCGQPDPRWASINLGIALCIECSGIHRSLGVHCSKVRSLTLDS--WEPE-LLKLMCELGNHVINDIYEASADDVGGKKPTPSSSRQEKEMWIRAKYVDRKFLR 183
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009914.1 (pep scaffold:Pmarinus_7.0:GL476634:533628:626389:1 gene:ENSPMAG00000008958.1 transcript:ENSPMAT00000009914.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.1814 bits (191), Expect = 5.679e-15 Identity = 33/74 (44.59%), Postives = 48/74 (64.86%), Query Frame = 3
Query: 828 ESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW 1049
+ N +C DCG PNP+W S+NL ++CI CSG+HR+L + SR++S LD+ W D L ++M +GN S W
Sbjct: 542 QGNDVCIDCGAPNPDWASLNLGALICIECSGIHRNLGSHVSRVRSLDLDE--WPDE-LAQVMVSVGNAMSRGVW 612
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006444.1 (pep scaffold:Pmarinus_7.0:GL477103:5377:54062:-1 gene:ENSPMAG00000005792.1 transcript:ENSPMAT00000006444.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.559 bits (179), Expect = 1.454e-13 Identity = 33/79 (41.77%), Postives = 45/79 (56.96%), Query Frame = 3
Query: 831 SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQN 1067
N C DC P+P+W S+NL ++CI CSG+HR+L T SR++S LD E L +M IGN +N W + Q
Sbjct: 573 GNAFCVDCDAPSPDWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPLE---LAAVMLAIGNATANGVWEADTQG 648
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: GCS1 (ADP-ribosylation factor GTPase activating protein (ARF GAP); involved in ER-Golgi transport; required for prospore membrane formation; regulates phospholipase Spo14p; shares functional similarity with Glo3p; GCS1 has a paralog, SPS18, that arose from the whole genome duplication [Source:SGD;Acc:S000002385]) HSP 1 Score: 60.4622 bits (145), Expect = 6.086e-10 Identity = 26/67 (38.81%), Postives = 39/67 (58.21%), Query Frame = 3
Query: 831 SNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNE 1031
+NK C DCG PNP+W + +C+ C+G+HR L S ++S +DQ E+ + M+K GNE
Sbjct: 22 ANKKCMDCGAPNPQWATPKFGAFICLECAGIHRGLGVHISFVRSITMDQFKPEE---LLRMEKGGNE 85
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: AGE2 (ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif [Source:SGD;Acc:S000001306]) HSP 1 Score: 58.5362 bits (140), Expect = 1.457e-9 Identity = 29/84 (34.52%), Postives = 49/84 (58.33%), Query Frame = 3
Query: 801 KILKQIYTNESNKLCADCGYP-NPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW 1049
K L + + N CADC +P W S +L V +CI C+G+HRSL T S+++S LD W++ L+++++ N +N ++
Sbjct: 9 KALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLD--TWKEEHLVKLIQFKNNLRANSYY 90
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: GLO3 (ADP-ribosylation factor GTPase activating protein (ARF GAP); involved in ER-Golgi transport; shares functional similarity with Gcs1p [Source:SGD;Acc:S000000924]) HSP 1 Score: 59.6918 bits (143), Expect = 1.592e-9 Identity = 29/86 (33.72%), Postives = 50/86 (58.14%), Query Frame = 3
Query: 801 KILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKN 1058
++ +++ +N N++C DCG NP W S+ V+LCI CS +HR++ + ++S+ LD+ W + L K GN + F+ KN
Sbjct: 17 QVFQKLGSNMENRVCFDCGNKNPTWTSVPFGVMLCIQCSAVHRNMGVHITFVKSSTLDK--WTINNLRRF-KLGGNHKARDFFLKN 99
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: AGE1 (ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif [Source:SGD;Acc:S000002932]) HSP 1 Score: 59.3066 bits (142), Expect = 1.789e-9 Identity = 34/77 (44.16%), Postives = 47/77 (61.04%), Query Frame = 3
Query: 762 SEAINIAFMGGENK-----ILKQIYTNESNKLCADCG-YPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILD 974
++ + A G N+ I+++I ++SN C DCG EWVSINL ILCI CSG+HRSL + S+I+S LD
Sbjct: 156 TQHFSFANAGASNRDELLSIVRKI--DKSNLKCCDCGSTATVEWVSINLLCILCIKCSGVHRSLGSHISKIRSLTLD 230
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Match: GTS1 (Protein involved in Arf3p regulation and in transcription regulation; localizes to the nucleus and to endocytic patches; contains an N-terminal Zn-finger and ArfGAP homology domain, a C-terminal glutamine-rich region, and a UBA (ubiquitin associated) domain; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms, endocytosis; expression oscillates in a pattern similar to metabolic oscillations [Source:SGD;Acc:S000003149]) HSP 1 Score: 52.7582 bits (125), Expect = 1.686e-7 Identity = 39/123 (31.71%), Postives = 63/123 (51.22%), Query Frame = 3
Query: 798 NKILKQ-IYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSH-----SRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-INSKYIEKKFIDTEF 1145
++ LK+ I ++E+ C +CG P W S+NL V LC C+ +HR + S S ++S +D+ ED + E++ GN+ + FW N +N F D + I YI K+I +F
Sbjct: 14 DRELKELINSSENANKCGECGNFYPTWCSVNLGVFLCGRCASVHRKVFGSRDDDAFSNVKSLSMDRWTRED--IDELVSLGGNKGNARFW--NPKNVPFPFDGDDDKAIVEHYIRDKYILGKF 132
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO34673 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNK8]) HSP 1 Score: 102.834 bits (255), Expect = 4.821e-22 Identity = 77/218 (35.32%), Postives = 116/218 (53.21%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNP-EWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSE-----INSKYIEKKF--IDTEFINLSDNEIKNRLRSSVATDDVFLTMKLY---HSIKF-PYDSEFIKEILLIARNSNQYLQEKFL 1322
TF + E+ V+ W + AI I + +L+ ++TN SN+ CADCG +P S+N V +C NC G HRSL ++ S+ +S ++D++IW D L E+M KIGNEN+N + I P S I +KY KK+ I E+ N+ + + LR SV TDDV T +L ++K+ P DSE + L +A + + LQ + L
Sbjct: 948 TFSFQVENDFEVSSWIEAVQRAIQIGL--SDPAVLEYVFTNPSNRKCADCGNKDPYPHASVNHLVCICGNCCGSHRSLGSNISKPRSLLMDKKIWNDD-LKELMVKIGNENANKLLEFKIPDDDRIRPDADSAKRREFICAKYEYKKYSKILPEYGNV--DVLGQALRESVQTDDVMRTFELIINRVNVKYVPTDSEDQRTPLELAVAAGKNLQAELL 1160
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO42956 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S052]) HSP 1 Score: 85.8853 bits (211), Expect = 4.643e-17 Identity = 42/119 (35.29%), Postives = 64/119 (53.78%), Query Frame = 3
Query: 795 ENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFIN 1151
E ++ I N +C DCG PNP+W S+NL ++CI CSG+HR++ T SR++S LD W S + +M IGN +N W N PS E ++I K+ + +F++
Sbjct: 548 EGNDIQAIRAIPGNNICVDCGAPNPDWASLNLGALMCIECSGVHRNIGTHVSRVRSLDLDD--WP-SEVTAVMCSIGNSLANSIWEGRIGNREKPTPSSSREEKERWIRSKYENKDFLS 663
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO43007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZU7]) HSP 1 Score: 78.9518 bits (193), Expect = 7.174e-15 Identity = 41/113 (36.28%), Postives = 64/113 (56.64%), Query Frame = 3
Query: 810 KQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFI 1148
++I E NK CADC P P+W SINL + +CI CSG+HRS+ S+++S LD+ W D +E M+ +GN N + N + FP L+ + K+ + FI +++
Sbjct: 513 ERIRKVEGNKYCADCSAPRPDWASINLGITVCIECSGVHRSMGVHVSKVRSLTLDK--W-DGDTVEFMEAMGNTKVNKIFEANLND----FPK-LTRDSGKHDRQAFIKLKYV 617
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO47919 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKJ9]) HSP 1 Score: 75.8702 bits (185), Expect = 1.756e-14 Identity = 46/116 (39.66%), Postives = 61/116 (52.59%), Query Frame = 3
Query: 807 LKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKN----KQNSSTIFPSDLSE--INSKYIEKKFID 1136
L ++ N CADCG +PEW S + + +CI CSG+HR+L T S ++S LD W D L + M + GNE SN W KN + P L E I +KY K+FID
Sbjct: 8 LLELAKRPGNNTCADCGAKHPEWASASKGIFICITCSGVHRNLGTQISVVKSLRLD--TWTDERL-QFMIENGNEKSNAIWAKNVPICYRRPKCTDPHVLREQWIRAKYERKEFID 120
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Match: EDO33091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST58]) HSP 1 Score: 70.0922 bits (170), Expect = 3.825e-14 Identity = 41/120 (34.17%), Postives = 60/120 (50.00%), Query Frame = 3
Query: 804 ILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW-------YKNKQNSSTIFPSDLSEINSKYIEKKFIDTE 1142
IL + E NK CADC P W S NL V +CI C+G+HR+L S+++S LD W + + I + GN + L+W ++ Q S + + I KY +KKFI +
Sbjct: 19 ILVDMLKEEKNKYCADCAAKGPRWASWNLGVFICIRCAGIHRNLGVHISKVKSVNLDS--WTEEQMASI-QSWGNRRAGLYWECYLPEDFRRPQTDSAM----EAFIRKKYEQKKFIKKD 131
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:NCBI gene;Acc:101162821]) HSP 1 Score: 105.145 bits (261), Expect = 2.437e-22 Identity = 76/302 (25.17%), Postives = 139/302 (46.03%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYF-------KYAEVRIDSNEASNVSSYILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
L+ F + DI +P+ I++ + N+F I+ N ++F + + + WV + + + F K+ + + + + Y I +D+ LH E + I VI + ++ + + S L +F ES +W L EAI A + ++ ++I++N SN++CADC NP+W SINLCV++C NC+G HRSL + S++QS LD +W + ++++ +GN+ +N FW + S + E +I +K+ + F
Sbjct: 499 LMYFGSEKDIYPRGVIPL-AVIQMARLAKDNKFEIVTSNRIFVFRTDNEVLRRRWVTTLQEHIRDQLVFGRRRFGPGSHCQKHGVLEL---KGTKSKVYTAISTDQIWLHKSEQCFRNGIGIT--VIEARGATIRDGKHRS------FDLITPYKSFSFTAESERDKRDWMEALQEAI--AETLSDYEVAEKIWSNRSNRMCADCKAVNPDWASINLCVVICKNCAGQHRSLGSMVSKVQSLKLDTSVWSNE-IVQLFIMVGNDRANDFWAAHLSQSEELDCDASPEQRKDFITQKYKEGRF 785 HSP 2 Score: 76.2554 bits (186), Expect = 1.957e-13 Identity = 55/167 (32.93%), Postives = 86/167 (51.50%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+D I FI GL E I+RK GA +I L E K + + + + DV LK++FR ++PI L + +A K+ +L + + + S+P +N L + LY +QK AD N+M +K+L+L A S+ D GE +I++DLID + VF
Sbjct: 1098 VDSCIAFITQYGLGHEGIYRKNGAKTRIRLLMEEFRKDARNVKLRIGDHFIEDVTDVLKRFFREIDDPIFMAELHAFWQEAAKIPQKRQRLERYKEIIRSLPRVNQTTLAALIGHLYRVQKCADLNQMCTKNLSLLFAPSLFQTD-GKGEHEVKIVEDLIDNYLFVF 1263
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:NCBI gene;Acc:101162821]) HSP 1 Score: 105.145 bits (261), Expect = 2.746e-22 Identity = 76/302 (25.17%), Postives = 139/302 (46.03%), Query Frame = 3
Query: 261 LIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYF-------KYAEVRIDSNEASNVSSYILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF 1145
L+ F + DI +P+ I++ + N+F I+ N ++F + + + WV + + + F K+ + + + + Y I +D+ LH E + I VI + ++ + + S L +F ES +W L EAI A + ++ ++I++N SN++CADC NP+W SINLCV++C NC+G HRSL + S++QS LD +W + ++++ +GN+ +N FW + S + E +I +K+ + F
Sbjct: 543 LMYFGSEKDIYPRGVIPL-AVIQMARLAKDNKFEIVTSNRIFVFRTDNEVLRRRWVTTLQEHIRDQLVFGRRRFGPGSHCQKHGVLEL---KGTKSKVYTAISTDQIWLHKSEQCFRNGIGIT--VIEARGATIRDGKHRS------FDLITPYKSFSFTAESERDKRDWMEALQEAI--AETLSDYEVAEKIWSNRSNRMCADCKAVNPDWASINLCVVICKNCAGQHRSLGSMVSKVQSLKLDTSVWSNE-IVQLFIMVGNDRANDFWAAHLSQSEELDCDASPEQRKDFITQKYKEGRF 829 HSP 2 Score: 76.2554 bits (186), Expect = 1.919e-13 Identity = 55/167 (32.93%), Postives = 86/167 (51.50%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVF 2522
+D I FI GL E I+RK GA +I L E K + + + + DV LK++FR ++PI L + +A K+ +L + + + S+P +N L + LY +QK AD N+M +K+L+L A S+ D GE +I++DLID + VF
Sbjct: 1142 VDSCIAFITQYGLGHEGIYRKNGAKTRIRLLMEEFRKDARNVKLRIGDHFIEDVTDVLKRFFREIDDPIFMAELHAFWQEAAKIPQKRQRLERYKEIIRSLPRVNQTTLAALIGHLYRVQKCADLNQMCTKNLSLLFAPSLFQTD-GKGEHEVKIVEDLIDNYLFVF 1307
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: ENSORLT00000045891.1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Source:NCBI gene;Acc:105356443]) HSP 1 Score: 100.138 bits (248), Expect = 8.322e-21 Identity = 62/208 (29.81%), Postives = 105/208 (50.48%), Query Frame = 3
Query: 723 ESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINLSDN-----EIKNRLRSSVATDDVFLTMKLYHS---IKFPYDSEFIKEILLIARNSNQYLQEKFL 1322
ES + EW + E+I + ++ ++I+ NE+N+ CADC P PEW S NL V++C C+G HR L S S+++S LD IW + L+E ++GN+ +N FW N + +E + +I +K+ + ++ L + ++ L +SV T DV TM L + + L+A+ + Q +Q +FL
Sbjct: 616 ESEQEKAEWVEAIQESIVETL--SDYEVAEKIWFNEANRSCADCRAPQPEWASTNLGVVICKKCAGQHRFLGPSISKVRSLKLDSSIWSNE-LVEFFLEVGNKKANSFWAANLPLEEELHIGASTEQRATFIRRKYKERKYRRLLEGFEYVVQLNQALCASVVTPDVLQTMALVFTGANVMCATGDPTYSTPYLLAQRAGQKVQMEFL 820
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: ENSORLT00000040486.1 (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 [Source:NCBI gene;Acc:101156673]) HSP 1 Score: 93.2041 bits (230), Expect = 9.618e-19 Identity = 65/213 (30.52%), Postives = 110/213 (51.64%), Query Frame = 3
Query: 705 TFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEF-----INLSDNEIKNRLRSSVATDDVFLTMKLYHSIK--FPYDSEFIKEILLIARNSNQYLQEKFL 1322
T + ES++ + W L AI A +++ ++ N NK+CADCG NP+W S+NL + +C +C+ HR+L+++ S+++S +LD +IW + +I++ GN+ +N W + + P E SK+I+ K+ + ++ S ++ RL V T D+ TM L S P D + I L A +NQ LQ +FL
Sbjct: 479 TLNLTVESNKDLTTWLNCLEAAICSALSC--SQVALRLRENPHNKVCADCGEANPDWASVNLLLSICKSCADHHRNLSSNLSKVRS-MLDTKIWTEP-IIQLFVTYGNKLANQVWAPAVPAAEQLHPKSTDEERSKFIQDKYSRGRYRRVHPLSSSRAMMEQRLCQVVCTSDLEETMSLICSGAKVCPSDPQSPSPISL-AEKANQALQMQFL 686 HSP 2 Score: 67.0106 bits (162), Expect = 1.173e-10 Identity = 39/128 (30.47%), Postives = 63/128 (49.22%), Query Frame = 3
Query: 2022 IDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKM 2405
I++ I+ I T GLK E ++R+ G K+N L E ++ SPN ++ + V D S LKKY R + I+ + + A + S + + + +P+ N L YM+Q F+ ENKM
Sbjct: 921 IERCISHITTYGLKVEGVYRRCGLATKVNKLVEALKTSPNSAPLEGDEQGVLDACSALKKYIRD-QDSIVPTTQRQRWLQAAANPDESCRFKEYRRLLRQLPDNNKATLNALFGHFYMVQVFSQENKM 1047
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Match: acap2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 [Source:NCBI gene;Acc:101158345]) HSP 1 Score: 92.0485 bits (227), Expect = 1.546e-18 Identity = 50/144 (34.72%), Postives = 77/144 (53.47%), Query Frame = 3
Query: 789 GGENK--------ILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQ--NSSTIFPSDLSEINSKYIEKKFIDTEFINL-SDNEIKNRLRS 1187
GGE K L+++ N C DCG P+P W SINL + LCI CSG+HRSL S+++S LD WE L+++M ++GN+ N + ++ + P D YI+ K++D F+ SD E++N++ S
Sbjct: 391 GGEPKERLLKGESALQKVLAIPGNSCCCDCGQPDPRWASINLGITLCIQCSGIHRSLGVHFSKVRSLTLDS--WEPE-LLKLMCELGNKAINEIYEARREELGARKPQPGDPRHEVEAYIKAKYVDRRFVRRPSDEELRNKVVS 531
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000070668.1 (SMESG000070668.1) HSP 1 Score: 1954.1 bits (5061), Expect = 0.000e+0 Identity = 1001/1022 (97.95%), Postives = 1006/1022 (98.43%), Query Frame = 3
Query: 153 MTVTCLSEIEDNILIHSNLKVNGSGCDCYCALIKYRLIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSSYILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSNSIQDQTIIKDKIFKISYNNEEKLADLFSVSLLCTCISINIEELLTPAIYINICCIYYTDIELIWYDSTNESLVITLFNNCQFFKNPKSRTSKKYPITVHRLSFFDQSNVIKQFQLDLFKLLMPNHFVELTFNSNLFMNLEVKLNENNTIKCKSHVDEQGIIFYFPIAIIFDLKNSTKIQLIDDKIISIKFNNDQIEIVTNNFGSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIREFYIHPFLKNFLLIPTNENKRVGFLDRGISFSMIRMTINQCATVKQVVQKLFRNLEVELWNFQTKTTRFGNKTLKRFVNLNENTENSIVCPRKISDCYENYFVFLPKQSNADRNIRCLFKCEIKLKLENYRDFTLNLQYPNSYEFFPRNQTLESNFKLPWTDVKVLRYHMRNVNKIIMLSENGIYKCNFCNTETLREFLIFFDQFK 3218
MTVTCLSEIEDNILIHSNLKVNGSGCDCYCALIKYRLIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFM+SDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSSYILIRSDEYLLHIYENL EHAQNICSHVINLKFYSLENSRS SSVNNRCLKLFGKSITFKI+FESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCI+CSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFW KNKQ S IFPSDLSEINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSN IQDQTIIK+KIFKISYNNEEKLADLFSVSLLCTCISINIEEL+TPAIYINICCIYYTDIELIWYDSTNESLVITLFNNCQFFKNPKSRTSKK PITVHRLSFFDQSNVIKQFQLDLFKLLMPNHFVELTFNSNLFMNLEVKLNENNTIKCKSHVDEQGIIFYFPIAIIFDLKNSTKIQLIDDKIISIKFNNDQIEI TNNFGSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASC KKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVL KTVELLYMIQKFADENKMDSKSLALSTALSIISEDENH EISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIREFYIHPFLKNFLLIPTNENKRVGFLDRGISFSMIRMTINQCATVKQVVQKLFRN E ELWNFQ KTTRFGNKTLKRFVNLNENTENSIVCPRKISDCYENYFVFLPKQSNADRNIRCLFKCEIKLKLENYRDFTLNLQYPNSYEFFPRNQTLESNFKLPWT VKVLRYHMRNVNKIIMLSENGIYKCNFCNTETLREFLIFFDQFK
Sbjct: 1 MTVTCLSEIEDNILIHSNLKVNGSGCDCYCALIKYRLIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMNSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSSYILIRSDEYLLHIYENLDEHAQNICSHVINLKFYSLENSRSLSSVNNRCLKLFGKSITFKIKFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCISCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWNKNKQKLSIIFPSDLSEINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSNFIQDQTIIKEKIFKISYNNEEKLADLFSVSLLCTCISINIEELVTPAIYINICCIYYTDIELIWYDSTNESLVITLFNNCQFFKNPKSRTSKKNPITVHRLSFFDQSNVIKQFQLDLFKLLMPNHFVELTFNSNLFMNLEVKLNENNTIKCKSHVDEQGIIFYFPIAIIFDLKNSTKIQLIDDKIISIKFNNDQIEIATNNFGSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCFKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLLKTVELLYMIQKFADENKMDSKSLALSTALSIISEDENHREISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIREFYIHPFLKNFLLIPTNENKRVGFLDRGISFSMIRMTINQCATVKQVVQKLFRNFEFELWNFQNKTTRFGNKTLKRFVNLNENTENSIVCPRKISDCYENYFVFLPKQSNADRNIRCLFKCEIKLKLENYRDFTLNLQYPNSYEFFPRNQTLESNFKLPWTGVKVLRYHMRNVNKIIMLSENGIYKCNFCNTETLREFLIFFDQFK 1022
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000070925.1 (SMESG000070925.1) HSP 1 Score: 806.209 bits (2081), Expect = 0.000e+0 Identity = 461/1035 (44.54%), Postives = 685/1035 (66.18%), Query Frame = 3
Query: 153 MTVTCLSEIEDNILIHSNLKVN-GSGCDCYCALIKYRLIIFKNSNDIISSKRLPINKSIRLQYIDNSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQ-LNYFKYAEVRIDSNEASNVSSYILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXX----XXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSNSIQDQTIIKDKIFKISYNNEEKLADLFSVSLLCTCISINIEE-LLTPAIYINICCIYYTDIELIWYDSTNESLVITLFNNCQF--FKNPKSRTSKKYPITVHRLSFFDQS-NVIKQFQLDLFKLLMPNHFVELTFNSNLFMNLEVKLNENNTIKCKSHVDEQGIIFYFPIAIIFDLKNSTKIQLIDD-KIISIKFNNDQIEIVTNNFGSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIREFYIHPFLKNFLLIPTNENKRVGFLDRGISFSMIRMTINQCATVKQVVQKLFRNLEVELWNFQTKTTRFGNKTLKRFVNLNENTENSIVCPRKISDCYENYFVFLPKQSNADRNIRCLFKCEIKLKLENYRDFTLNLQYPNSYEFF-PRNQTLESNFKLPWTDVKVLRYHMRNVNKI-IMLSENGIYKCNFCNTETLREFLIFFDQFK 3218
M++ CLSE+E+ + HS+L ++ + YC LI+ +IIFK S DIIS KRLPI +++ + +QF I++ + F D +II+ W+ +N L+ N+ + L + YAEV+ID S V +IL+ ++Y L I+ +L EH+ NI +HV+N KFYS++N S + L L GK ++FKI F+ + EW+ IL +A+ AF EN++L +IY NESN+ CADCG P+PEW+SINL VI+CINC+G+HRS TS SRIQSA+LD+ IW DS+LI+I+K IGNE SN FWYKN++ ++ + +KY+ KKFID EFINLS+ + K+ L+ SVA DDVFLTM+L+HSI F Y+SEF++E+L IARNSNQ+LQEKFLSVQP+ S + ++ +K+F+ISYN+ EKL LF V+L ISI +E+ ++TP +N+C I+Y +I L+WYD ESL+I++ C F F N K + + I ++R++FF QS ++ F+ +L KLLMP+ F+ + S LFM+L VK N + KCKS + + IIF PI+ ++DLK S K LID+ K I IKF D +E+ N +Q ++Y Y+ + ++ +PI+KMI+FII+RGLKSE IFR G ++K+N L++ IEKS N+FFIDP +YNV DV+SCLKKYFRS +EPIIT +LF++F A EN S K+ + +S +P NY V R +EL YMIQ + +MD SLA+S + S IS D + EIS++I+K+LI+ F +F YS K+ L + + P IIR FYIHP + N + I +E+K++ F+D+ +F + + +++ TVKQ++++LF + VELW+F +K TRF KT+KR + ++ +SI+ PR I Y++YFVF K++++ +R L++CE+KLK + Y +FTL + +PN+ +FF ++++L+ ++ +DV V R+H +N+ KI I+ NG KC F + E L+EFL F+DQF+
Sbjct: 1 MSLLCLSELEEQHIFHSSLILHLKQQSNMYCVLIESYMIIFKKSTDIISFKRLPITNKTKVECNEFGDQFSIIIRENTFTFSSPDVTIIETWIKNLNFLIGNFVLTKPLIDYNYAEVKIDQIGGSIV--FILLFCNDYNLIIFSSLKEHSDNIVTHVVNCKFYSVKNDSRDNSIASRSTIKSLVLIGKHLSFKISFKDESTLKEWECILLKAVKTAFGINENEVLTEIYENESNRCCADCGSPDPEWISINLSVIICINCAGIHRSFGTSFSRIQSAVLDECIWSDSYLIKILKTIGNEKSNSFWYKNQRKLTSTSTDYSLFVKNKYVSKKFIDDEFINLSEYDFKSHLQKSVAADDVFLTMRLWHSINFDYNSEFVEELLEIARNSNQFLQEKFLSVQPNSSKNFRNTITQNEKVFQISYNDSEKLKKLFLVTLSNNGISITMEDVIVTPVKLLNVCFIFYDNINLVWYDHDIESLIISINPQCNFNKFTNGKPINNCQ-QIDINRMAFFSQSKQILMDFRFELMKLLMPDEFINVNDESILFMDLYVKKNFESLSKCKSFIVDHEIIFSSPISALYDLKKSEKCDLIDEKKSIQIKFKVDYLELHAGNSENQKIIYTYIKRASKCLELLMDPINKMISFIISRGLKSEGIFRICGTIKKVNILHKSIEKSGNNFFIDPLIYNVYDVSSCLKKYFRSLDEPIITSNLFDIFRGALIEENQSRKITLYKEGLSFLPRDNYSVFRDLLELFYMIQMSVTDTRMDCSSLAISVSSSFISFDHINTEISSKIMKELIENFIALFDYSGKKINDLERFVAGPEIVAQKIIRNFYIHPNI-NSVTIRNSESKKLNFIDKDANFVSVIINVDEYVTVKQIIERLFTDSNVELWHFLSKETRFSFKTIKRLIFPSDGIHDSILYPRTIL-TYDSYFVFRTKRNSSHVPLRQLYQCEVKLKTDKYHEFTLLMNFPNTLQFFNHKSRSLDPDYNFLLSDVIVFRFHTKNIAKIFILFGTNGFLKCKFDSNEVLQEFLSFYDQFR 1030
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000070925.1 (SMESG000070925.1) HSP 1 Score: 733.021 bits (1891), Expect = 0.000e+0 Identity = 409/891 (45.90%), Postives = 600/891 (67.34%), Query Frame = 3
Query: 579 NLVEHAQNICSHVINLKFYSLEXXXX----XXXXXXXXLKLFGKSITFKIRFESSELVNEWKIILSEAINIAFMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTEFINLSDNEIKNRLRSSVATDDVFLTMKLYHSIKFPYDSEFIKEILLIARNSNQYLQEKFLSVQPDLSNSIQDQTIIKDKIFKISYNNEEKLADLFSVSLLCTCISINIEE-LLTPAIYINICCIYYTDIELIWYDSTNESLVITLFNNCQF--FKNPKSRTSKKYPITVHRLSFFDQS-NVIKQFQLDLFKLLMPNHFVELTFNSNLFMNLEVKLNENNTIKCKSHVDEQGIIFYFPIAIIFDLKNSTKIQLIDD-KIISIKFNNDQIEIVTNNFGSQNLVYNYLNLFTNQRPIMFNPIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFIDPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXXXXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTALIKHIENPVEKEPIIIREFYIHPFLKNFLLIPTNENKRVGFLDRGISFSMIRMTINQCATVKQVVQKLFRNLEVELWNFQTKTTRFGNKTLKRFVNLNENTENSIVCPRKISDCYENYFVFLPKQSNADRNIRCLFKCEIKLKLENYRDFTLNLQYPNSYEFF-PRNQTLESNFKLPWTDVKVLRYHMRNVNKI-IMLSENGIYKCNFCNTETLREFLIFFDQFK 3218
+L EH+ NI +HV+N KFYS++N S + L L GK ++FKI F+ + EW+ IL +A+ AF EN++L +IY NESN+ CADCG P+PEW+SINL VI+CINC+G+HRS TS SRIQSA+LD+ IW DS+LI+I+K IGNE SN FWYKN++ ++ + +KY+ KKFID EFINLS+ + K+ L+ SVA DDVFLTM+L+HSI F Y+SEF++E+L IARNSNQ+LQEKFLSVQP+ S + ++ +K+F+ISYN+ EKL LF V+L ISI +E+ ++TP +N+C I+Y +I L+WYD ESL+I++ C F F N K + + I ++R++FF QS ++ F+ +L KLLMP+ F+ + S LFM+L VK N + KCKS + + IIF PI+ ++DLK S K LID+ K I IKF D +E+ N +Q ++Y Y+ + ++ +PI+KMI+FII+RGLKSE IFR G ++K+N L++ IEKS N+FFIDP +YNV DV+SCLKKYFRS +EPIIT +LF++F A EN S K+ + +S +P NY V R +EL YMIQ + +MD SLA+S + S IS D + EIS++I+K+LI+ F +F YS K+ L + + P IIR FYIHP + N + I +E+K++ F+D+ +F + + +++ TVKQ++++LF + VELW+F +K TRF KT+KR + ++ +SI+ PR I Y++YFVF K++++ +R L++CE+KLK + Y +FTL + +PN+ +FF ++++L+ ++ +DV V R+H +N+ KI I+ NG KC F + E L+EFL F+DQF+
Sbjct: 14 SLKEHSDNIVTHVVNCKFYSVKNDSRDNSIASRSTIKSLVLIGKHLSFKISFKDESTLKEWECILLKAVKTAFGINENEVLTEIYENESNRCCADCGSPDPEWISINLSVIICINCAGIHRSFGTSFSRIQSAVLDECIWSDSYLIKILKTIGNEKSNSFWYKNQRKLTSTSTDYSLFVKNKYVSKKFIDDEFINLSEYDFKSHLQKSVAADDVFLTMRLWHSINFDYNSEFVEELLEIARNSNQFLQEKFLSVQPNSSKNFRNTITQNEKVFQISYNDSEKLKKLFLVTLSNNGISITMEDVIVTPVKLLNVCFIFYDNINLVWYDHDIESLIISINPQCNFNKFTNGKPINNCQ-QIDINRMAFFSQSKQILMDFRFELMKLLMPDEFINVNDESILFMDLYVKKNFESLSKCKSFIVDHEIIFSSPISALYDLKKSEKCDLIDEKKSIQIKFKVDYLELHAGNSENQKIIYTYIKRASKCLELLMDPINKMISFIISRGLKSEGIFRICGTIKKVNILHKSIEKSGNNFFIDPLIYNVYDVSSCLKKYFRSLDEPIITSNLFDIFRGALIEENQSRKITLYKEGLSFLPRDNYSVFRDLLELFYMIQMSVTDTRMDCSSLAISVSSSFISFDHINTEISSKIMKELIENFIALFDYSGKKINDLERFVAGPEIVAQKIIRNFYIHPNI-NSVTIRNSESKKLNFIDKDANFVSVIINVDEYVTVKQIIERLFTDSNVELWHFLSKETRFSFKTIKRLIFPSDGIHDSILYPRTIL-TYDSYFVFRTKRNSSHVPLRQLYQCEVKLKTDKYHEFTLLMNFPNTLQFFNHKSRSLDPDYNFLLSDVIVFRFHTKNIAKIFILFGTNGFLKCKFDSNEVLQEFLSFYDQFR 901
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000006535.1 (SMESG000006535.1) HSP 1 Score: 125.561 bits (314), Expect = 8.788e-29 Identity = 153/582 (26.29%), Postives = 249/582 (42.78%), Query Frame = 3
Query: 159 VTCLSEIEDN--ILIHSNL-----KVNGSGCDCYCALIKYRLIIFKNSNDIISSKRLPINKSIRLQYID--------NSNQFLILLGNFQYLFMHSDASIIKNWVNKINTLLLNYEDLQLNYFKYAEVRIDSNEASNVSS-YILIRSDEYLLHIYENLVEHAQNICSHVINLKFYSLEXXXXXXXXXXXXLKLFGKSITFKIRFESSELVNEW----KIILSEAINIA----FMGGENKILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDLSEINSKYIEKKFIDTE---FINLSDNEIKNR-LRSSVATDDVFLTMKLYHSIKFPYDSEFIKE-----ILLIARNSNQYLQEKFL-----------------SVQPDLSNSIQDQTIIKDKIF-KISYNNEEKLADLFSVSLLC-TCISINIEELLTPAIYINICCIYYTDIELIWYDSTNESLVITL---FNNCQFFKNPKSRTSKKYPITVHRLSFFDQSNVIKQFQLDLFKLLMPNHFVELTF 1739
+ C SE +DN + H + K+ S Y L+ +LI+F+ +S ++P+ + ++D + N+F + + F S W+N I L+ Y+ Q++ + + NV I ++ + Y+N + I H I L+ ++ + S+ L L +K+ FES L NEW II+ +AI+ GE+ I+++I N SN+ CA+C + EW S+NL + LC CSGLHR + + S+IQ D+ WE+ LI I + IGN N+N FW N D IN KY K+F + + F D++ NR L V T+++ TM+L+H D ++ E L A +Q LQ +L S+ PD N+ QT + K + I+ N +E F + L+ +CI I +C I + +I LI + NES I+L + P I+V +S DQSN ++ F+ + + L PN ++
Sbjct: 97 LPCFSEFDDNDRLEYHGPIVQIVQKLTSSRKSRYAVLMSNKLILFEKPEHKVSKVQIPLKSMKGIDWVDSVNCSNKDDCNKFKLETPVKSFKFQCSSHENAGKWINHIGKLI--YDKQQIDESDNSHLLKALVSLENVKGKRIFTIEPKFTIAYYDNDEDFKYGIAMHRIQLRSSGVKRDGNDSNS----LSLITSYRRYKLTFESINLCNEWFHQITIIIQKAISATCSRNARPGED-IMREINKNASNRFCAECKSTDIEWASVNLFITLCAKCSGLHRKMGPNISKIQGIFTDESTWENGNLIRIFQIIGNNNANKFWLANFDGEQPEI--DYRFINDKYSRKRFSERKEAIFDKYKDSQALNRELIECVKTENIIRTMQLFH---IGADINYVSEPSGLNALETAGKYHQMLQLTYLNSQCKCQIRDWRSDLFDSIDPDPDNT--KQTPYQGKYWLSINQNPKE-----FRIILIWKSCIQI------LDCSNKEVCKILFRNICLI-REKLNESEGISLVIVVQETDYSTKPADYVESG--ISVIEISSADQSNNLRDFKNAIGQNLSPNFVPSFSY 650 HSP 2 Score: 74.3294 bits (181), Expect = 4.266e-13 Identity = 71/260 (27.31%), Postives = 123/260 (47.31%), Query Frame = 3
Query: 2019 PIDKMITFIITRGLKSEFIFRKVGAVRKINALYELIEKSPNDFFI---DPNVYNVNDVASCLKKYFRSFNEPIITDSLFNLFCDACKLENTSSKLAQLEFTVSSMPEINYQVLRKTVELLYMIQKFADENKMDXXXXXXXXXX-XXXXEDENHGEISTEILKDLIDYFETVFGYSPKERTALIK-------HIENPVEKEPIIIREFYIHPFLKNFLLIPTNENKRVGFLDRGISFSMI--RMTINQCATVKQVVQKLFR 2759
P+ KMI + G + E +FRKVG+V++ +Y+ + PN + + DP DVAS LK +FR +P++T + + A + ++ K + ++ +P INYQ LR + LL I K D +M+ +L+ S I D+ + +IL LI ++ +F + +E + K I++ E ++R+ YI P L+ FL N + G ++ ++ I Q T K + KLF+
Sbjct: 772 PVSKMIRHLQLHGTQIEGLFRKVGSVKEAERIYDQLISDPNSYVLTNSDPY-----DVASALKLFFRKLEDPLLTKLYYENWIAAVDIRDSEKKFEYFKEIINKLPVINYQTLRLLIFLLVNIDKNNDVTQMNPDNLSTSFNTCLISGSDQMFNAKNLQILPYLIRNYQDLFDVT-QEELEMEKLYNKERMKIKDFTPLEISLLRQIYILPELERFLKPDINFERESGHKKTDFFKELLTKQLRIEQSMTSKSLFGKLFK 1025
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Match: SMESG000018614.1 (SMESG000018614.1) HSP 1 Score: 82.8037 bits (203), Expect = 9.827e-16 Identity = 46/124 (37.10%), Postives = 69/124 (55.65%), Query Frame = 3
Query: 801 KILKQIYTNESNKLCADCGYPNPEWVSINLCVILCINCSGLHRSLATSHSRIQSAILDQRIWEDSFLIEIMKKIGNENSNLFWYKNKQNSSTIFPSDL--SEINS------KYIEKKFIDTEFI 1148
K++++I N CADCG P P+W S+NL ++CI CSG+HR L T SR++S LDQ W + +MK IGN +N W + + + P +L E+NS ++I K+ EF+
Sbjct: 659 KMIQEIGFVSGNDFCADCGQPKPDWASLNLGELVCIECSGVHRKLGTHISRVRSLQLDQ--WAPEWQA-VMKAIGNTVANTVW----EAAVNVSPRNLKKPELNSPAKDKEEWIRSKYERREFL 775 The following BLAST results are available for this feature:
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30012050 ID=SMED30012050|Name=arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like|organism=Schmidtea mediterranea sexual|type=transcript|length=3266bpback to top protein sequence of SMED30012050-orf-1 >SMED30012050-orf-1 ID=SMED30012050-orf-1|Name=SMED30012050-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1023bp MTVTCLSEIEDNILIHSNLKVNGSGCDCYCALIKYRLIIFKNSNDIISSKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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