5'-AMP-activated protein kinase subunit beta-1

Overview


Name	5'-AMP-activated protein kinase subunit beta-1
Smed ID	SMED30012046
Length (bp)	981

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of 5'-AMP-activated protein kinase subunit beta-1 (SMED30012046) t-SNE clustered cells

Violin plots show distribution of expression levels for 5'-AMP-activated protein kinase subunit beta-1 (SMED30012046) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 5'-AMP-activated protein kinase subunit beta-1 (SMED30012046) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30012046

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30012046	h1SMcG0002353	SmedASXL_001433	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30012046	h1SMcG0002353	dd_Smed_v4_6112_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30012046	h1SMcG0002353	dd_Smed_v4_6112_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30012046	h1SMcG0002353	dd_Smed_v4_6112_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30012046	h1SMcG0002353	dd_Smed_v4_6112_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30012046	h1SMcG0002353	dd_Smed_v6_6112_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30012046	h1SMcG0002353	OX_Smed_1.0.16686	ox_Smed_v2	PMID:24238224 Kao et al., 2013
epidermis	SMED30012046	h1SMcG0002353	dd_Smed_v4_6112_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Human
Match: PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:9379])

HSP 1 Score: 146.362 bits (368), Expect = 2.622e-41
Identity = 83/204 (40.69%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RW+ +  K + ISGSFNNW   IPL K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++HVK++D      F   D+      ++   S  D+   SP G Y Q +      +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKD ++ LSAT RY+ K++T +LYK I
Sbjct:   78 PTVIRWS-EGGKEVFISGSFNNWSTKIPLIKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD------FEVFDALKLDSMESSETSCRDLSS-SPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI 272

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Human
Match: PRKAB1 (protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378])

HSP 1 Score: 144.05 bits (362), Expect = 1.928e-40
Identity = 82/204 (40.20%), Postives = 116/204 (56.86%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++   +++  I++   G H YK+F+DG W HDPS+ +V +  GT +NI+ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-HNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++   +++  I++   G H YK+F+DG W HDPS+ +V +  GT +NI+ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-HNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Human
Match: PRKAB1 (protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378])

HSP 1 Score: 74.3294 bits (181), Expect = 4.756e-16
Identity = 40/89 (44.94%), Postives = 54/89 (60.67%), Query Frame = 1

Query:  607 SPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   16 SPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 104

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Celegans
Match: aakb-2 (AMP-Activated Kinase Beta subunit [Source:UniProtKB/TrEMBL;Acc:Q9NAH7])

HSP 1 Score: 125.946 bits (315), Expect = 5.629e-34
Identity = 75/260 (28.85%), Postives = 127/260 (48.85%), Query Frame = 1

Query:  136 PNSKASKYHHSPLFISMHRKAHIFERTNEKPKEFYDEIN----FSIPTFFRWTGKVN---KSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXX----XXXXXXXXXXYQAPSISN---PDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PN KA    H  +  +      +    +  P   +D+ N       P  FRW+   N   + + I GS++NW+  IP+ K   D +  II+   G + YK+ +DG+W  D +Q   Q+  G  +N+++++++D    +          +      ++ S  N   P+ + L     ++Q +P   +      P   P  L + +L+  T  + +P++LP P HV LNHMYA SIKD ++ LS+T RYR KF+T +LYK +
Sbjct:   16 PNDKAGLRRHRMMSETAKIAGQVLPNPDGGPPMIFDDGNEDKSGECPVVFRWSFTQNAQPRVVHIVGSWDNWQTRIPMVKSTND-FSTIIDLQPGQYEYKFQVDGSWVVDDNQGKAQDVHGNENNMINIQDSDFAVFEALDEDFQSSTAGEVLRGESESTKNHDTPNDRELEKLRSFTQEIPSMDMLRKAAGPPVIPPQLMQVLLNKETPESCDPNVLPEPNHVMLNHMYALSIKDSVMVLSSTQRYRKKFVTTLLYKPV 274

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Celegans
Match: aakb-1 (AMP-Activated Kinase Beta subunit [Source:UniProtKB/TrEMBL;Acc:Q9XUY2])

HSP 1 Score: 125.561 bits (314), Expect = 7.460e-34
Identity = 71/213 (33.33%), Postives = 105/213 (49.30%), Query Frame = 1

Query:  262 PTFFRWT--GKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEAD-------STSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            P  F+W       + + I GS++ W   IPL K   D +  I++   G H YK+ +D  W  D +Q+   N  G  +N+V + EAD          +      ++  +S     S   P+ + L     + Q  P R   +    P   P +L + IL+  T    +P++LP P HV LNH+YA SIKDG++ LSAT RYR KF+T +LYK I
Sbjct:   58 PVVFKWNINNATPRQVYICGSWDGWNTKIPLVKSTSD-FSTIVDLEPGKHEYKFMVDSKWVVDDNQQKTGNNLGGENNVVMIDEADFEVFDALDKDLASSNAGEALRNSHPTKESHDTPNDRELEKLHQFGQETPTRVDFNKAAAPPVLPPHLLQVILNKDTPVQCDPNVLPEPDHVMLNHLYALSIKDGVMVLSATHRYRKKFVTTLLYKPI 269

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Query:  262 PTFFRWT--GKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEAD-------STSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            P  F+W       + + I GS++ W   IPL K   D +  I++   G H YK+ +D  W  D +Q+   N  G  +N+V + EAD          +      ++  +S     S   P+ + L     + Q  P R   +    P   P +L + IL+  T    +P++LP P HV LNH+YA SIKDG++ LSAT RYR KF+T +LYK I
Sbjct:   58 PVVFKWNINNATPRQVYICGSWDGWNTKIPLVKSTSD-FSTIVDLEPGKHEYKFMVDSKWVVDDNQQKTGNNLGGENNVVMIDEADFEVFDALDKDLASSNAGEALRNSHPTKESHDTPNDRELEKLHQFGQETPTRVDFNKAAAPPVLPPHLLQVILNKDTPVQCDPNVLPEPDHVMLNHLYALSIKDGVMVLSATHRYRKKFVTTLLYKPI 269

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Fly
Match: alc (gene:FBgn0260972 transcript:FBtr0088625)

HSP 1 Score: 136.732 bits (343), Expect = 1.805e-38
Identity = 78/207 (37.68%), Postives = 118/207 (57.00%), Query Frame = 1

Query:  256 SIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFV-IINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            ++PT  RW G   K+++ISG+F++W+   P++       FV II+   G H YK+ +DG W HDP  + V+N  G  +N+V V+E+D                 +QA +  + ++   +   +YSQ VP+    +    P   P +L + IL+  T  + EP+LLP P HV LNH+YA SIKDG++ LSAT RYR K++T +LYK I
Sbjct:   33 ALPTVLRWDGG-GKNVTISGTFSDWK---PMAMVRSHQNFVTIIDLPEGDHQYKFCVDGEWKHDPKLKSVENAEGQRNNLVSVRESD--------------FEVFQALAKDSENVTNYA-EKEYSQEVPQVKPWEKVSGPPVLPPHLLQVILNKDTPLSCEPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYRKKYVTTLLYKPI 220

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Fly
Match: alc (gene:FBgn0260972 transcript:FBtr0088624)

HSP 1 Score: 136.346 bits (342), Expect = 3.836e-37
Identity = 78/207 (37.68%), Postives = 118/207 (57.00%), Query Frame = 1

Query:  256 SIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFV-IINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            ++PT  RW G   K+++ISG+F++W+   P++       FV II+   G H YK+ +DG W HDP  + V+N  G  +N+V V+E+D                 +QA +  + ++   +   +YSQ VP+    +    P   P +L + IL+  T  + EP+LLP P HV LNH+YA SIKDG++ LSAT RYR K++T +LYK I
Sbjct:  154 ALPTVLRWDGG-GKNVTISGTFSDWK---PMAMVRSHQNFVTIIDLPEGDHQYKFCVDGEWKHDPKLKSVENAEGQRNNLVSVRESD--------------FEVFQALAKDSENVTNYAEK-EYSQEVPQVKPWEKVSGPPVLPPHLLQVILNKDTPLSCEPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYRKKYVTTLLYKPI 341

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Zebrafish
Match: prkab1a (protein kinase, AMP-activated, beta 1 non-catalytic subunit, a [Source:ZFIN;Acc:ZDB-GENE-040718-377])

HSP 1 Score: 155.221 bits (391), Expect = 5.283e-45
Identity = 92/244 (37.70%), Postives = 132/244 (54.10%), Query Frame = 1

Query:  148 ASKYHHSPLFISMHRKAHIFERTNEKPKEFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            A  +H   L   + ++  I  R + +  E  D ++   PT FRWTG   K + ISGSFNNW N IPL +  ++++  I++   G H YK+++DG W HDP++ VV N  GT +NI+ VK+ D            +        S    DM  LS  P G Y Q+       +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   40 ADIFHGEDLKAPLEKEEFIEWRPDLEGSEKTDTLDR--PTVFRWTG-AGKEVYISGSFNNWTNKIPLIRS-QNNFVAIVDLPEGEHQYKFYVDGLWTHDPTEPVVTNQLGTVNNIIQVKKTD-----------FEVFDALMVDSQKCSDMSDLSSSPPGPYHQDAYTPKQEEKFKSPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 268

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Zebrafish
Match: prkab1b (protein kinase, AMP-activated, beta 1 non-catalytic subunit, b [Source:ZFIN;Acc:ZDB-GENE-030131-7172])

HSP 1 Score: 143.28 bits (360), Expect = 2.098e-40
Identity = 81/206 (39.32%), Postives = 114/206 (55.34%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRW G   K I +SGSFNNW   IPL+K   +++  II+   G H YK+++DG+W  DP + VV N  G  +N++ V++ D            +     +  S    DM  LS  P G Y Q+       D    P   P +L + +L+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   68 PTVFRWKGP-GKEIYLSGSFNNWATKIPLNKS-HNNFVAIIDLPEGEHQYKFYVDGHWTLDPKEPVVTNKSGVVNNVIKVRKTD-----------FEVFDALKTDSEKCADMSDLSSSPPGPYHQDPYSTKSEDKLRSPPILPPHLLQVLLNKDTGISCDPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 260

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Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRW G   K I +SGSFNNW   IPL+K   +++  II+   G H YK+++DG+W  DP + VV N  G  +N++ V++ D            +     +  S    DM  LS  P G Y Q+       D    P   P +L + +L+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   68 PTVFRWKGP-GKEIYLSGSFNNWATKIPLNKS-HNNFVAIIDLPEGEHQYKFYVDGHWTLDPKEPVVTNKSGVVNNVIKVRKTD-----------FEVFDALKTDSEKCADMSDLSSSPPGPYHQDPYSTKSEDKLRSPPILPPHLLQVLLNKDTGISCDPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 260

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Zebrafish
Match: CABZ01083448.1 (pep chromosome:GRCz11:2:58739111:58742863:1 gene:ENSDARG00000067817.5 transcript:ENSDART00000097690.5 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01083448.1)

HSP 1 Score: 113.235 bits (282), Expect = 5.750e-29
Identity = 68/203 (33.50%), Postives = 105/203 (51.72%), Query Frame = 1

Query:  265 TFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            T  RW G   + + I+GSFNNW + IPL+K   D +  I++   G H YK+F+DG W HDPS+ ++            +K +D   +  F           ++ S++     + S   D  +   + T +         PS+ +   L+     + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   77 TVIRWAGG-GREVFITGSFNNWSSKIPLNKSHND-FVAILDLPEGEHQYKFFVDGQWLHDPSEVMMMMMMNQISQRSVIKRSD---VHMFTELQVSLFKCSESSSLTCSRPAQFSKLVDVVKAETQWTSS------FIIPSHFSHRRLNRNFNISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTSLLYKPI 268

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Zebrafish
Match: prkab1a (protein kinase, AMP-activated, beta 1 non-catalytic subunit, a [Source:ZFIN;Acc:ZDB-GENE-040718-377])

HSP 1 Score: 97.0561 bits (240), Expect = 2.070e-23
Identity = 48/122 (39.34%), Postives = 72/122 (59.02%), Query Frame = 1

Query:  148 ASKYHHSPLFISMHRKAHIFERTNEKPKEFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEAD 513
            A  +H   L   + ++  I  R + +  E  D ++   PT FRWTG   K + ISGSFNNW N IPL +  ++++  I++   G H YK+++DG W HDP++ VV N  GT +NI+ VK+ D
Sbjct:   40 ADIFHGEDLKAPLEKEEFIEWRPDLEGSEKTDTLDR--PTVFRWTG-AGKEVYISGSFNNWTNKIPLIRS-QNNFVAIVDLPEGEHQYKFYVDGLWTHDPTEPVVTNQLGTVNNIIQVKKTD 157

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Xenopus
Match: prkab2 (protein kinase, AMP-activated, beta 2 non-catalytic subunit [Source:NCBI gene;Acc:100127782])

HSP 1 Score: 149.828 bits (377), Expect = 1.136e-42
Identity = 85/204 (41.67%), Postives = 118/204 (57.84%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RWT +  K + ISGSFNNW   IPL K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++HVK++D      F   D+      ++   S  D+   SP G Y Q +      +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   77 PTVIRWT-EGGKEVFISGSFNNWTAKIPLIKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD------FEVFDALKLDSMESSDTSARDLSS-SPPGLYGQELYAYKPEERYKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 271

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Xenopus
Match: PRKAB1 (protein kinase, AMP-activated, beta 1 non-catalytic subunit [Source:NCBI gene;Acc:100380160])

HSP 1 Score: 113.235 bits (282), Expect = 4.880e-29
Identity = 80/266 (30.08%), Postives = 129/266 (48.50%), Query Frame = 1

Query:   25 MGNQSAVLKYKNEIEKDLSF------DRSRLSPYKCEVSSEVFPNSKASKYHHSPLFISMHRKAHIFERTNEKPKEFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRL--SPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIK 798
            MGN S+     +++ +D +       DR+++     E  +++FP  ++        F++     H  E  ++ P +       + PT FRWTG   K I +SG+FNNW   IPL +   +++F I++   G H YK+ +DG W HDP++ V  +  GT +NI+ V++ D            +        S    D+  L  SP G Y Q+     + +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIK
Sbjct:    1 MGNTSSERPGPHKVRRDSTGAVSKGDDRAKILMDSPE-DADMFPAEESKGSTEKEEFLAWQ---HDLEVNDKMPSQ-------ARPTVFRWTGG-GKEIYLSGTFNNWAK-IPLIRS-HNNFFAILDLPEGEHQYKFLVDGQWTHDPAEPVTTSQLGTVNNIIQVQKTD-----------FEVFDALMVDSQKGSDISDLSSSPPGPYQQDPYNCKLEERFKTPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIK 241

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Xenopus
Match: PRKAB1 (protein kinase, AMP-activated, beta 1 non-catalytic subunit [Source:NCBI gene;Acc:100380160])

HSP 1 Score: 77.411 bits (189), Expect = 2.985e-17
Identity = 40/89 (44.94%), Postives = 56/89 (62.92%), Query Frame = 1

Query:  607 SPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            SP G Y Q+     + +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   16 SPPGPYQQDPYNCKLEERFKTPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 104

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Mouse
Match: Prkab1 (protein kinase, AMP-activated, beta 1 non-catalytic subunit [Source:MGI Symbol;Acc:MGI:1336167])

HSP 1 Score: 146.747 bits (369), Expect = 1.130e-41
Identity = 82/204 (40.20%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++  ++++  I++   G H YK+F+DG W HDPS+ +V +  GT +NI+ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-QNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYMSKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++  ++++  I++   G H YK+F+DG W HDPS+ +V +  GT +NI+ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-QNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYMSKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Mouse
Match: Prkab2 (protein kinase, AMP-activated, beta 2 non-catalytic subunit [Source:MGI Symbol;Acc:MGI:1336185])

HSP 1 Score: 145.591 bits (366), Expect = 3.246e-41
Identity = 83/204 (40.69%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RW+ +  K + ISGSFNNW   IPL K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++HVK++D      F   D+      ++   S  D+   SP G Y Q +      +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKD ++ LSAT RY+ K++T +LYK I
Sbjct:   77 PTVIRWS-EGGKEVFISGSFNNWSTKIPLIKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD------FEVFDALKLDSMESSETSCRDLSS-SPPGPYGQEMYVFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI 271

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Mouse
Match: Prkab2 (protein kinase, AMP-activated, beta 2 non-catalytic subunit [Source:MGI Symbol;Acc:MGI:1336185])

HSP 1 Score: 89.3521 bits (220), Expect = 5.753e-21
Identity = 40/84 (47.62%), Postives = 55/84 (65.48%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEAD 513
            PT  RW+ +  K + ISGSFNNW   IPL K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++HVK++D
Sbjct:   77 PTVIRWS-EGGKEVFISGSFNNWSTKIPLIKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD 158

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Mouse
Match: Prkab1 (protein kinase, AMP-activated, beta 1 non-catalytic subunit [Source:MGI Symbol;Acc:MGI:1336167])

HSP 1 Score: 70.4774 bits (171), Expect = 4.430e-14
Identity = 30/64 (46.88%), Postives = 45/64 (70.31%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQ 453
            PT FRWTG   K + +SGSFNNW + +PL++  ++++  I++   G H YK+F+DG W HDPS+
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTR-SQNNFVAILDLPEGEHQYKFFVDGQWTHDPSE 139

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
Match: sp|Q9R078|AAKB1_MOUSE (5'-AMP-activated protein kinase subunit beta-1 OS=Mus musculus OX=10090 GN=Prkab1 PE=1 SV=2)

HSP 1 Score: 146.747 bits (369), Expect = 7.908e-41
Identity = 82/204 (40.20%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++  ++++  I++   G H YK+F+DG W HDPS+ +V +  GT +NI+ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-QNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYMSKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
Match: sp|O43741|AAKB2_HUMAN (5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens OX=9606 GN=PRKAB2 PE=1 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 1.259e-40
Identity = 83/204 (40.69%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RW+ +  K + ISGSFNNW   IPL K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++HVK++D      F   D+      ++   S  D+   SP G Y Q +      +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKD ++ LSAT RY+ K++T +LYK I
Sbjct:   78 PTVIRWS-EGGKEVFISGSFNNWSTKIPLIKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD------FEVFDALKLDSMESSETSCRDLSS-SPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI 272

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
Match: sp|P80386|AAKB1_RAT (5'-AMP-activated protein kinase subunit beta-1 OS=Rattus norvegicus OX=10116 GN=Prkab1 PE=1 SV=4)

HSP 1 Score: 145.976 bits (367), Expect = 1.510e-40
Identity = 82/204 (40.20%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++  ++++  I++   G H YK+F+DG W HDPS+ +V +  GT +NI+ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-QNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYISKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
Match: sp|Q6PAM0|AAKB2_MOUSE (5'-AMP-activated protein kinase subunit beta-2 OS=Mus musculus OX=10090 GN=Prkab2 PE=1 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 2.271e-40
Identity = 83/204 (40.69%), Postives = 117/204 (57.35%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RW+ +  K + ISGSFNNW   IPL K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++HVK++D      F   D+      ++   S  D+   SP G Y Q +      +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKD ++ LSAT RY+ K++T +LYK I
Sbjct:   77 PTVIRWS-EGGKEVFISGSFNNWSTKIPLIKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD------FEVFDALKLDSMESSETSCRDLSS-SPPGPYGQEMYVFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI 271

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
Match: sp|Q5BIS9|AAKB1_BOVIN (5'-AMP-activated protein kinase subunit beta-1 OS=Bos taurus OX=9913 GN=PRKAB1 PE=2 SV=3)

HSP 1 Score: 145.206 bits (365), Expect = 3.882e-40
Identity = 82/204 (40.20%), Postives = 116/204 (56.86%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW + +PL++   +++  I++   G H YK+F+DG W HDPS+ VV +  GT +N++ VK+ D    D    D    S   +  S         SP G Y Q        +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   79 PTVFRWTGG-GKEVYLSGSFNNW-SKLPLTRS-HNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPVVTSQLGTVNNVIQVKKTDFEVFDALMVDSQKCSDVSELSS---------SPPGPYHQEPYISKPEERFKAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 270

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
Match: A0A0L8H7W3 (AMPKBI domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22020788mg PE=4 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 2.109e-44
Identity = 89/212 (41.98%), Postives = 124/212 (58.49%), Query Frame = 1

Query:  259 IPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSI--SNPDMKRL-----SPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            +PT FRW G   K + +SGSFNNW+N IPL+K   D +F I+N   G H YK+++DG W HD ++  V N+ GT +N+V V ++D                 ++A +I   N   KR      SP+GDY Q +P R  +D    P   P +L + IL+  T ++ EP LLP P HV LNH+YA SIKDG++ LS T R+R K++T +LYK I
Sbjct:   72 LPTVFRWEGAA-KEVCLSGSFNNWKNTIPLAKSNGD-FFTILNLPEGEHQYKFYVDGQWLHDQNEPTVPNSMGTLNNVVVVNKSD--------------FEVFEALAIDSENSGNKRKNDVAGSPSGDYGQEIPPRR-SDKIAGPPFIPPHLLQVILNKDTPAHCEPILLPEPNHVMLNHLYALSIKDGVMVLSTTHRFRKKYVTTLLYKPI 266

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
Match: W4YLN6 (AMPKBI domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 160.999 bits (406), Expect = 1.024e-43
Identity = 83/210 (39.52%), Postives = 120/210 (57.14%), Query Frame = 1

Query:  256 SIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRL----SPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            ++P  FRW G   KS++++GSFNNW   IP+ K   D +  I+N   G H YK+++DG W H+P Q +  NTFGT +N + V ++D                 ++A +I +   K +    SP GDY+Q++P + +      P   P  L + IL+       EP+LLP P HV LNH+YA SIKDG++ LSAT RYR K++T +LYK I
Sbjct:   81 ALPVVFRWEGG-GKSVAVAGSFNNWNTKIPMIKSQGD-FTAIVNLPEGQHEYKFYVDGQWIHNPRQPLQSNTFGTVNNFISVSKSD--------------FEVFEALAIDSEREKGVDMSGSPPGDYNQDIPSQELQQRTTGPPILPPQLLQVILNKDIGPQYEPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYRKKYVTSLLYKPI 274

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
Match: A0A4S2LKB1 (AMPKBI domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006547 PE=4 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 1.424e-43
Identity = 109/309 (35.28%), Postives = 159/309 (51.46%), Query Frame = 1

Query:   31 NQSAVLKYKNEIEKDLSFDRSRLSPYKCEVSSE---VFPNSKASKYHHSPLFISMHRK-----AHIFERTNEKPKEFYD--EINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVP-------RRTITDYDIVPMQ-----------FPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            +  +++ Y +E+ +D S  + R +   C   ++     P S AS    SP+ +          A    RT ++ +  +   +     PT FRW G   K I ISG+FNNWE  IP+ K     Y VII+C+ G+H YKYFIDG WYHDP++  V N  GT +N+VHVK +D  +I     D ++S         S+PD    SP G+Y + +P       RR+ +     P+             P +L + IL+  T  + +P+LLP P HV +NH+YA SIKDG+I LS   RYR KF++ + YK I
Sbjct:   35 DHQSLVPYPDELLRDDSLRKHRPASTGCPSPTDRRLFLPQSGASTCS-SPVTVDRPTTLTQTFARPARRTAQQQRSSHQTPDSELKCPTVFRWDGG-GKDIYISGTFNNWEKRIPMVKRNSGVY-VIIDCTPGTHEYKYFIDGAWYHDPTKPTVDNGLGTKNNVVHVKFSDFDAIQALELDQANSRHRSSVMESSDPDSMGHSPPGNYGRYIPSHPSEFQRRSGSFGSPGPIAPGIGTLTQPPLLPPHLLQGILNMDTGVHCDPNLLPPPNHVIVNHLYALSIKDGVIVLSVITRYRQKFVSTVFYKPI 340

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
Match: H2KT28 (5'-AMP-activated protein kinase subunit beta-2 OS=Clonorchis sinensis OX=79923 GN=CLF_111537 PE=4 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 6.090e-43
Identity = 110/309 (35.60%), Postives = 159/309 (51.46%), Query Frame = 1

Query:   31 NQSAVLKYKNEIEKDLSFDRSRLSPYKCEVSSE---VFPNSKASKYHHSPLFISMHRK-----AHIFERTNEKPKEFYD--EINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVP-------RRTITDYDIVPMQ-----------FPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            +  +V+ Y +E+ +D S  + R +   C   ++     P S AS    SP+ +          A    RT ++ +  +   +     PT FRW G   K I ISG+FNNWE  IP+ K     Y VII+C+ G+H YKYFIDG WYHDP++  V N  GT +N+VHVK +D  +I     D ++S         S+PD    SP G+Y + +P       RR+ +     P+             P +L + IL+  T  + +P+LLP P HV +NH+YA SIKDG+I LS   RYR KF++ + YK I
Sbjct:  129 DHQSVIPYPDELLRDTSLRKHRPASTGCPSPTDRRLFLPQSGASTCS-SPVTVDRPTTLTQTFARPARRTAQQQRFNHQTPDSELKCPTVFRWDGG-GKDIYISGTFNNWEKRIPMVKRNSGVY-VIIDCTPGTHEYKYFIDGAWYHDPTKPTVDNGLGTKNNVVHVKFSDFDAIQALELDQANSRHRSSVMESSDPDSMGHSPPGNYGRYIPSHPSEFQRRSGSFGSPGPIAPGIGTLTQPPLLPPHLLQGILNMDTGVHCDPNLLPPPNHVIVNHLYALSIKDGVIVLSVITRYRQKFVSTVFYKPI 434

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
Match: A0A4V3SED2 (AMPKBI domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006547 PE=4 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 8.674e-43
Identity = 109/309 (35.28%), Postives = 159/309 (51.46%), Query Frame = 1

Query:   31 NQSAVLKYKNEIEKDLSFDRSRLSPYKCEVSSE---VFPNSKASKYHHSPLFISMHRK-----AHIFERTNEKPKEFYD--EINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVP-------RRTITDYDIVPMQ-----------FPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            +  +++ Y +E+ +D S  + R +   C   ++     P S AS    SP+ +          A    RT ++ +  +   +     PT FRW G   K I ISG+FNNWE  IP+ K     Y VII+C+ G+H YKYFIDG WYHDP++  V N  GT +N+VHVK +D  +I     D ++S         S+PD    SP G+Y + +P       RR+ +     P+             P +L + IL+  T  + +P+LLP P HV +NH+YA SIKDG+I LS   RYR KF++ + YK I
Sbjct:  109 DHQSLVPYPDELLRDDSLRKHRPASTGCPSPTDRRLFLPQSGASTCS-SPVTVDRPTTLTQTFARPARRTAQQQRSSHQTPDSELKCPTVFRWDGG-GKDIYISGTFNNWEKRIPMVKRNSGVY-VIIDCTPGTHEYKYFIDGAWYHDPTKPTVDNGLGTKNNVVHVKFSDFDAIQALELDQANSRHRSSVMESSDPDSMGHSPPGNYGRYIPSHPSEFQRRSGSFGSPGPIAPGIGTLTQPPLLPPHLLQGILNMDTGVHCDPNLLPPPNHVIVNHLYALSIKDGVIVLSVITRYRQKFVSTVFYKPI 414

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BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
Match: prkab1a (5'-AMP-activated protein kinase subunit beta-1-like [Source:NCBI gene;Acc:111195052])

HSP 1 Score: 157.147 bits (396), Expect = 1.028e-45
Identity = 86/216 (39.81%), Postives = 123/216 (56.94%), Query Frame = 1

Query:  232 EFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            E  D+   + PT FRWTG   + + ISGSFNNW N IPL++  ++++  I++   G H YK+++DG W HDP++ VV N  GT +NI+ VK+ D            +        S    DM  LS  P G Y Q+     + +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   66 EGGDKGLLARPTVFRWTGS-GREVYISGSFNNWTNKIPLTRS-QNNFVAIVDLPEGEHQYKFYVDGQWTHDPTEPVVTNQLGTVNNIIQVKKTD-----------FEVFDALMVDSQKCSDMSDLSSSPPGPYHQDAYVPKLDEKFKSPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 268

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
Match: prkab1b (5'-AMP-activated protein kinase subunit beta-1 [Source:NCBI gene;Acc:103026611])

HSP 1 Score: 151.369 bits (381), Expect = 1.253e-43
Identity = 84/206 (40.78%), Postives = 115/206 (55.83%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT FRWTG   K + +SGSFNNW N IPLSK    ++  +++   G H YK+++DGNW  DP Q VV +  GT +NI+ VK+ D            +     +  S    DM  +S  P G Y Q        D    P   P +L + +L+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   66 PTVFRWTGPA-KDVYVSGSFNNWANKIPLSKS-HSNFVAVVDLPEGEHQYKFYVDGNWTLDPKQPVVTSKSGTVNNIIQVKKTD-----------FEVFDALKTDSEKCADMSDMSGSPPGPYHQEPYSTKSEDRLRSPPILPPHLLQVLLNKDTGVSCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 258

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
Match: PRKAB2 (5'-AMP-activated protein kinase subunit beta-2-like [Source:NCBI gene;Acc:103047649])

HSP 1 Score: 151.369 bits (381), Expect = 1.344e-43
Identity = 84/206 (40.78%), Postives = 115/206 (55.83%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RW G   K + I+GSFNNW   IPL+K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++ VK++D            +     Q  S+   D   LS  P G Y Q V      +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   75 PTVIRWGGG-GKEVYIAGSFNNWSTKIPLNKSHND-FVAILDLPEGEHQYKFFVDGQWLHDPSEPVVTSQMGTINNLIQVKKSD-----------FEVFDALQVDSLECSDTSDLSSSPPGPYGQEVYMFRPEERFKAPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTSLLYKPI 267

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
Match: prkab1b (5'-AMP-activated protein kinase subunit beta-1 [Source:NCBI gene;Acc:103026611])

HSP 1 Score: 136.732 bits (343), Expect = 7.286e-38
Identity = 78/194 (40.21%), Postives = 106/194 (54.64%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYR 837
            PT FRWTG   K + +SGSFNNW N IPLSK    ++  +++   G H YK+++DGNW  DP Q VV +  GT +NI+ VK+ D            +     +  S    DM  +S  P G Y Q        D    P   P +L + +L+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+
Sbjct:   66 PTVFRWTGPA-KDVYVSGSFNNWANKIPLSKS-HSNFVAVVDLPEGEHQYKFYVDGNWTLDPKQPVVTSKSGTVNNIIQVKKTD-----------FEVFDALKTDSEKCADMSDMSGSPPGPYHQEPYSTKSEDRLRSPPILPPHLLQVLLNKDTGVSCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYK 246

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
Match: prkab1a (5'-AMP-activated protein kinase subunit beta-1-like [Source:NCBI gene;Acc:111195052])

HSP 1 Score: 126.716 bits (317), Expect = 2.634e-34
Identity = 73/193 (37.82%), Postives = 104/193 (53.89%), Query Frame = 1

Query:  232 EFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRL--SPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDG 804
            E  D+   + PT FRWTG   + + ISGSFNNW N IPL++  ++++  I++   G H YK+++DG W HDP++ VV N  GT +NI+ VK+ D            +        S    DM  L  SP G Y Q+     + +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIK G
Sbjct:   66 EGGDKGLLARPTVFRWTGS-GREVYISGSFNNWTNKIPLTRS-QNNFVAIVDLPEGEHQYKFYVDGQWTHDPTEPVVTNQLGTVNNIIQVKKTD-----------FEVFDALMVDSQKCSDMSDLSSSPPGPYHQDAYVPKLDEKFKSPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKVG 245

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Yeast
Match: SIP2 (One of three beta subunits of the Snf1 kinase complex; involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane; SIP2 has a paralog, GAL83, that arose from the whole genome duplication [Source:SGD;Acc:S000003176])

HSP 1 Score: 60.8474 bits (146), Expect = 6.029e-11
Identity = 60/257 (23.35%), Postives = 100/257 (38.91%), Query Frame = 1

Query:  259 IPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGED--SYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--------------------------PTGDYSQNVP------------------RRTITDYD-IVPMQFPSYLNESILDA--ATQSNLEP---SLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            +P   RW    +K + ++GSF  W   I L    ++  S+ V +    G+H +++ +D             +  G F N + V++ +    +E            +A S+  P   R S                          P  +Y+ ++P                  +++ TD   + P Q P  L   IL+   ATQ          LP P HV LNH+  SSIK   +C+++ +RY+ K++T ILY  I
Sbjct:  164 VPVEIRWQQGGSK-VYVTGSFTKWRKMIGLIPDSDNNGSFHVKLRLLPGTHRFRFIVDNELRVSDFLPTATDQMGNFVNYIEVRQPEKNPTNEKIRSK-------EADSMRPPTSDRSSIALQIGKDPDDFGDGYTRFHEDLSPRPPLEYTTDIPAVFTDPSVMERYYYTLDRQQSNTDTSWLTPPQLPPQLENVILNKYYATQDQFNENNSGALPIPNHVVLNHLVTSSIKHNTLCVASIVRYKQKYVTQILYTPI 412

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Yeast
Match: GAL83 (One of three possible beta-subunits of the Snf1 kinase complex; allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; necessary and sufficient for phosphorylation of the Mig2p transcription factor in response to alkaline stress; functionally redundant with SIP1 and SIP2 for the phosphorylation of Mig1p in response to glucose deprivation; contains a glycogen-binding domain [Source:SGD;Acc:S000000829])

HSP 1 Score: 56.6102 bits (135), Expect = 1.729e-9
Identity = 27/72 (37.50%), Postives = 43/72 (59.72%), Query Frame = 1

Query:  664 IVPMQFPSYLNESILDA--ATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            + P Q P +L   IL++    Q++     LP P HV LNH+  SSIK   +C+++ +RY+ K++T ILY  +
Sbjct:  345 LTPPQLPPHLENVILNSYSNAQTDNTSGALPIPNHVILNHLATSSIKHNTLCVASIVRYKQKYVTQILYTPL 416

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Nematostella
Match: EDO33540 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRX9])

HSP 1 Score: 134.42 bits (337), Expect = 1.986e-37
Identity = 79/214 (36.92%), Postives = 115/214 (53.74%), Query Frame = 1

Query:  253 FSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPR-------RTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
             +IPT  RW     + + +SGSFN+W+  IP++    + +  II    G H YK+ +DG W HDP+     + FG  +N++ V++ D    D    D + S +     S+S       SP G Y Q +P        R  T+  + P+  P +L   IL+     + +PSLLP P +V LNH+YA SIKDG++ LSAT RYR KF+T +LYK I
Sbjct:   67 MTIPTVIRWENG-GRKVLLSGSFNDWKTRIPMNYS-NNEFTAIIELPEGDHEYKFCVDGRWVHDPNGPTTNDNFGGRNNVISVRKTDMDVFDALDTDANLSINSGSIKSVSG------SPPGTYGQIIPSHVTPVIVRDGTNASVPPI-LPPHLLHVILNKDIVDHDDPSLLPEPDYVSLNHLYALSIKDGVMTLSATFRYREKFVTTLLYKPI 271

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Medaka
Match: prkab1a (5'-AMP-activated protein kinase subunit beta-1 [Source:NCBI gene;Acc:101155912])

HSP 1 Score: 150.214 bits (378), Expect = 5.097e-43
Identity = 85/210 (40.48%), Postives = 122/210 (58.10%), Query Frame = 1

Query:  250 NFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQN--VPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            N   PT FRWTG   K + +SGSFNNW N IPL +  ++++  I++   G H YK+++DG W HDP++ V+ +  GT +NI+ VK+ D    D    D   SS                SP G Y Q+  VP++    +   P+  P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   73 NLDRPTVFRWTGD-GKEVFVSGSFNNWANKIPLIRS-QNTFVAIVDLPEGEHQYKFYVDGQWTHDPTEPVITSQLGTVNNIIQVKKTDFEVFDALMVDSQKSSDMSDL---------SSSPPGPYHQDPYVPKQE-EKFKSPPI-LPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 269

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Medaka
Match: PRKAB2 (5'-AMP-activated protein kinase subunit beta-2 [Source:NCBI gene;Acc:101166167])

HSP 1 Score: 148.288 bits (373), Expect = 2.221e-42
Identity = 83/206 (40.29%), Postives = 114/206 (55.34%), Query Frame = 1

Query:  262 PTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            PT  RW G   K + I+GSFNNW   IPL+K   D +  I++   G H YK+F+DG W HDPS+ VV +  GT +N++ VK++D            +     Q  S+   D   LS  P G Y Q         +   P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   76 PTVIRWGGG-GKEVYIAGSFNNWNTKIPLNKSHND-FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIQVKKSD-----------FEVFDALQVDSLECSDTSDLSSSPPGPYGQEQYIFRPEKHFKAPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTSLLYKPI 268

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Medaka
Match: prkab1b (5'-AMP-activated protein kinase subunit beta-1 [Source:NCBI gene;Acc:101165238])

HSP 1 Score: 141.739 bits (356), Expect = 7.972e-40
Identity = 84/250 (33.60%), Postives = 128/250 (51.20%), Query Frame = 1

Query:  172 LFISMHRKAHIFERTNEK-PKEFYDEINF-------------SIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            + +     A +F+R + K P+E  + + +             + PT FRW G   K + +SGSFNNW   IPL++  + ++  I++   G H YK+ +DG W  DP+  V  +  G+ +N++ VK  D            +     +  S  + DM  LS  P G Y QN       D    P   P +L + +L+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   29 IMMDSSEDADLFQREDAKAPQEMQEFLAWQEDLDCDSKSPTHARPTVFRWAGAA-KEVFVSGSFNNWATKIPLNRS-QKNFVAIVDLPEGDHQYKFCVDGQWTLDPAGAVATSKTGSVNNVIQVKRTD-----------FEVFDALRIDSEDSADMSDLSSSPPGPYQQNAYVMKPEDKLKQPPILPPHLLQVLLNKDTGISCDPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 265

[Close]

Query:  172 LFISMHRKAHIFERTNEK-PKEFYDEINF-------------SIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLS--PTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            + +     A +F+R + K P+E  + + +             + PT FRW G   K + +SGSFNNW   IPL++  + ++  I++   G H YK+ +DG W  DP+  V  +  G+ +N++ VK  D            +     +  S  + DM  LS  P G Y QN       D    P   P +L + +L+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   29 IMMDSSEDADLFQREDAKAPQEMQEFLAWQEDLDCDSKSPTHARPTVFRWAGAA-KEVFVSGSFNNWATKIPLNRS-QKNFVAIVDLPEGDHQYKFCVDGQWTLDPAGAVATSKTGSVNNVIQVKRTD-----------FEVFDALRIDSEDSADMSDLSSSPPGPYQQNAYVMKPEDKLKQPPILPPHLLQVLLNKDTGISCDPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 265

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Medaka
Match: prkab1a (5'-AMP-activated protein kinase subunit beta-1 [Source:NCBI gene;Acc:101155912])

HSP 1 Score: 112.079 bits (279), Expect = 1.764e-29
Identity = 62/173 (35.84%), Postives = 99/173 (57.23%), Query Frame = 1

Query:  361 EDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQN--VPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            ++++  I++   G H YK+++DG W HDP++ V+ +  GT +NI+ VK+ D          +   +    +   S+      SP G Y Q+  VP++   +    P   P +L + IL+  T  + +P+LLP P HV LNH+YA SIKDG++ LSAT RY+ K++T +LYK I
Sbjct:   24 QNTFVAIVDLPEGEHQYKFYVDGQWTHDPTEPVITSQLGTVNNIIQVKKTD---------FEVFDALMVDSQKSSDMSDLSSSPPGPYHQDPYVPKQE--EKFKSPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 185

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Planmine SMEST
Match: SMESG000037698.1 (SMESG000037698.1)

HSP 1 Score: 296.59 bits (758), Expect = 5.440e-102
Identity = 158/158 (100.00%), Postives = 158/158 (100.00%), Query Frame = 1

Query:  406 MYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTIPL 879
            MYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIDEFFGDDSDSSSFYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTIPL
Sbjct:    1 MYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIDEFFGDDSDSSSFYQAPSISNPDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTIPL 158

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Planmine SMEST
Match: SMESG000018914.1 (SMESG000018914.1)

HSP 1 Score: 153.295 bits (386), Expect = 2.837e-44
Identity = 88/233 (37.77%), Postives = 123/233 (52.79%), Query Frame = 1

Query:  190 RKAHIFERTNEKPKEFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEADSTSIXXXXXXXXXXXXXYQAPSISNPDMKRLSPTGDYSQNVPRR-----TITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            ++ ++     +  + F D+    IPT FRW GK  K I ISGSFNNW+  IP+ K  +  Y+ IINC  G   YK+ +DG W HD +Q    N+FGT +N + V + D         D+  S     +  + NP+        +Y Q  P+R           + P   P YLNE++L+      ++P LL  P +VQ+NH+YASSI  G+  LS TIRYR+KFIT I YK I
Sbjct:   51 KQMNMINELKKNKESFEDDKTTGIPTVFRWHGKGEK-IYISGSFNNWKEKIPMKKS-DTVYYTIINCLPGHQSYKFHVDGEWVHDTAQPTEANSFGTMNNWLEVVQEDDNLELALSHDEKFSRKSSDSEFVENPN-------AEYGQIFPQRPNPLIGTKVTSVTPNFLPPYLNETVLNLEDSQKIDPILLRTPVYVQINHLYASSITSGIAALSVTIRYRTKFITTIFYKPI 274

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Planmine SMEST
Match: SMESG000080480.1 (SMESG000080480.1)

HSP 1 Score: 130.183 bits (326), Expect = 4.677e-35
Identity = 82/258 (31.78%), Postives = 128/258 (49.61%), Query Frame = 1

Query:  190 RKAHIFERTNEKPKEFYDEINFSIPTFFRWTGKVNKSISISGSFNNWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTFGTFDNIVHVKEAD-------------STSIXXXXXXXXXXXXXYQAPSISNPD-----------MKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNES------ILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            R+A + E       +  D  N +IPT F+W G   K + +SGSFN W+  IP+ K  + +++ I+    G H YK+ +DG W  D  Q +  N  G+ +N++ VK +D             S +          ++   ++P   N             ++  SP G YSQ +P++T+   +I   + P+           IL+  T  + +P+LLP P HV +NHMYA SIKDG+I LSA  RYR KF++ ++YK I
Sbjct:   73 REAKLLESHPSMCLDGIDSENKTIPTVFKWEGG-GKDVFLSGSFNLWKAKIPMVKS-KHNFYTIVELPKGEHQYKFIVDGVWKIDNKQHIANNDNGSQNNVISVKSSDFDVLEALKDDIANSKNSSNNVRQSIVTTVPLKSPGGLNESNKPKDGDNENHLQSSSPPGSYSQELPQKTLLS-EIGNEKSPTPPLLPPQLLQVILNKETGVHCDPNLLPQPNHVMINHMYALSIKDGVIVLSAIARYRQKFVSTVMYKPI 327

[Close]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Planmine SMEST
Match: SMESG000052906.1 (SMESG000052906.1)

HSP 1 Score: 45.4394 bits (106), Expect = 2.723e-6
Identity = 30/95 (31.58%), Postives = 46/95 (48.42%), Query Frame = 1

Query:  589 PDMKRLSPTGDYSQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLNHMYASSIKDGLICLSATIRYRSKFITIILYKTI 873
            P  K  +   DY  ++  R+    DI     P YL++ ++        +P+LLP  +HV  NH+   ++KD +I L    R+R K IT I  K I
Sbjct:    5 PSEKYTTDIPDYDNDIGLRSFITPDI-----PPYLDQKVIIENDLECDDPTLLPT-KHVIFNHILTHNLKDNIIRLGFVTRFREKIITTIFCKPI 93

The following BLAST results are available for this feature:

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Human
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Celegans
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Fly
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Zebrafish
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Xenopus
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Mouse
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Sea Lamprey
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Yeast
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Nematostella
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Medaka
BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Planmine SMEST

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
PRKAB2	2.622e-41	40.69	protein kinase AMP-activated non-catalytic subunit...	[more]
PRKAB1	1.928e-40	40.20	protein kinase AMP-activated non-catalytic subunit...	[more]
PRKAB1	1.928e-40	40.20	protein kinase AMP-activated non-catalytic subunit...	[more]
PRKAB1	4.756e-16	44.94	protein kinase AMP-activated non-catalytic subunit...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
aakb-2	5.629e-34	28.85	AMP-Activated Kinase Beta subunit [Source:UniProt...	[more]
aakb-1	7.460e-34	33.33	AMP-Activated Kinase Beta subunit [Source:UniProt...	[more]
aakb-1	7.460e-34	33.33	AMP-Activated Kinase Beta subunit [Source:UniProt...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
alc	1.805e-38	37.68	gene:FBgn0260972 transcript:FBtr0088625	[more]
alc	3.836e-37	37.68	gene:FBgn0260972 transcript:FBtr0088624	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prkab1a	5.283e-45	37.70	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]
prkab1b	2.098e-40	39.32	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]
prkab1b	2.098e-40	39.32	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]
CABZ01083448.1	5.750e-29	33.50	pep chromosome:GRCz11:2:58739111:58742863:1 gene:E...	[more]
prkab1a	2.070e-23	39.34	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
prkab2	1.136e-42	41.67	protein kinase, AMP-activated, beta 2 non-catalyti...	[more]
PRKAB1	4.880e-29	30.08	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]
PRKAB1	2.985e-17	44.94	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Prkab1	1.130e-41	40.20	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]
Prkab1	1.130e-41	40.20	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]
Prkab2	3.246e-41	40.69	protein kinase, AMP-activated, beta 2 non-catalyti...	[more]
Prkab2	5.753e-21	47.62	protein kinase, AMP-activated, beta 2 non-catalyti...	[more]
Prkab1	4.430e-14	46.88	protein kinase, AMP-activated, beta 1 non-catalyti...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9R078\|AAKB1_MOUSE	7.908e-41	40.20	5'-AMP-activated protein kinase subunit beta-1 OS=...	[more]
sp\|O43741\|AAKB2_HUMAN	1.259e-40	40.69	5'-AMP-activated protein kinase subunit beta-2 OS=...	[more]
sp\|P80386\|AAKB1_RAT	1.510e-40	40.20	5'-AMP-activated protein kinase subunit beta-1 OS=...	[more]
sp\|Q6PAM0\|AAKB2_MOUSE	2.271e-40	40.69	5'-AMP-activated protein kinase subunit beta-2 OS=...	[more]
sp\|Q5BIS9\|AAKB1_BOVIN	3.882e-40	40.20	5'-AMP-activated protein kinase subunit beta-1 OS=...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0L8H7W3	2.109e-44	41.98	AMPKBI domain-containing protein OS=Octopus bimacu...	[more]
W4YLN6	1.024e-43	39.52	AMPKBI domain-containing protein OS=Strongylocentr...	[more]
A0A4S2LKB1	1.424e-43	35.28	AMPKBI domain-containing protein OS=Opisthorchis f...	[more]
H2KT28	6.090e-43	35.60	5'-AMP-activated protein kinase subunit beta-2 OS=...	[more]
A0A4V3SED2	8.674e-43	35.28	AMPKBI domain-containing protein OS=Opisthorchis f...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prkab1a	1.028e-45	39.81	5'-AMP-activated protein kinase subunit beta-1-lik...	[more]
prkab1b	1.253e-43	40.78	5'-AMP-activated protein kinase subunit beta-1 [So...	[more]
PRKAB2	1.344e-43	40.78	5'-AMP-activated protein kinase subunit beta-2-lik...	[more]
prkab1b	7.286e-38	40.21	5'-AMP-activated protein kinase subunit beta-1 [So...	[more]
prkab1a	2.634e-34	37.82	5'-AMP-activated protein kinase subunit beta-1-lik...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
SIP2	6.029e-11	23.35	One of three beta subunits of the Snf1 kinase comp...	[more]
GAL83	1.729e-9	37.50	One of three possible beta-subunits of the Snf1 ki...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO33540	1.986e-37	36.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prkab1a	5.097e-43	40.48	5'-AMP-activated protein kinase subunit beta-1 [So...	[more]
PRKAB2	2.221e-42	40.29	5'-AMP-activated protein kinase subunit beta-2 [So...	[more]
prkab1b	7.972e-40	33.60	5'-AMP-activated protein kinase subunit beta-1 [So...	[more]
prkab1b	7.972e-40	33.60	5'-AMP-activated protein kinase subunit beta-1 [So...	[more]
prkab1a	1.764e-29	35.84	5'-AMP-activated protein kinase subunit beta-1 [So...	[more]

BLAST of 5'-AMP-activated protein kinase subunit beta-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000037698.1	5.440e-102	100.00	SMESG000037698.1	[more]
SMESG000018914.1	2.837e-44	37.77	SMESG000018914.1	[more]
SMESG000080480.1	4.677e-35	31.78	SMESG000080480.1	[more]
SMESG000052906.1	2.723e-6	31.58	SMESG000052906.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30012046 ID=SMED30012046|Name=5'-AMP-activated protein kinase subunit beta-1|organism=Schmidtea mediterranea sexual|type=transcript|length=981bp
AAAACTATATAAATCTTATATGTTATGGGAAATCAGTCAGCTGTATTAAA
ATATAAAAATGAAATCGAAAAAGATTTAAGCTTTGATAGATCCAGATTAA
GCCCATATAAATGTGAAGTATCTTCTGAGGTATTTCCCAATTCAAAGGCA
TCCAAGTATCACCATTCGCCTTTATTTATCAGTATGCACAGGAAAGCTCA
CATTTTTGAAAGGACAAATGAAAAACCGAAAGAATTTTATGACGAAATTA
ATTTTTCCATTCCAACATTTTTTAGATGGACTGGCAAAGTGAATAAGTCA
ATTTCAATTTCCGGATCTTTTAATAATTGGGAAAATAATATTCCTCTATC
AAAATGTGGCGAAGATTCTTATTTCGTAATAATCAACTGCAGTGCGGGAT
CTCACATGTACAAATATTTCATAGATGGCAACTGGTATCATGATCCGTCG
CAGGAAGTTGTCCAAAACACATTTGGAACATTTGACAACATTGTCCATGT
CAAAGAAGCTGATTCAACATCAATTGATGAATTTTTCGGCGACGACAGCG
ATTCCTCGTCTTTTTATCAAGCACCCAGCATAAGTAATCCAGATATGAAG
CGCCTGTCTCCTACGGGAGATTATTCGCAGAATGTACCTAGGCGCACAAT
TACTGACTACGACATCGTTCCTATGCAATTTCCTTCATATCTAAATGAGT
CTATTCTTGATGCAGCTACTCAATCAAATTTAGAGCCTTCTCTACTACCT
CATCCTCAACACGTTCAACTAAATCATATGTATGCTTCCTCAATCAAAGA
CGGACTTATTTGTCTCAGTGCAACAATCAGATATCGTTCGAAATTTATAA
CAATAATTCTTTATAAAACAATACCTTTATAAAACAATTGTGATATTTAA
TTAATACTCCAGATATTAGCAATTTCTATTATATTTAGAATATAATTACC
TTTTTAGAGGTCATCACTATTTATATTTGTG

protein sequence of SMED30012046-orf-1

>SMED30012046-orf-1 ID=SMED30012046-orf-1|Name=SMED30012046-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=286bp
MGNQSAVLKYKNEIEKDLSFDRSRLSPYKCEVSSEVFPNSKASKYHHSPL
FISMHRKAHIFERTNEKPKEFYDEINFSIPTFFRWTGKVNKSISISGSFN
NWENNIPLSKCGEDSYFVIINCSAGSHMYKYFIDGNWYHDPSQEVVQNTF
GTFDNIVHVKEADSTSIDEFFGDDSDSSSFYQAPSISNPDMKRLSPTGDY
SQNVPRRTITDYDIVPMQFPSYLNESILDAATQSNLEPSLLPHPQHVQLN
HMYASSIKDGLICLSATIRYRSKFITIILYKTIPL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0050790	regulation of catalytic activity
GO:0007165	signal transduction
GO:0016310	phosphorylation
GO:0045859	regulation of protein kinase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR013783	Ig-like_fold
IPR039160	AMPKB
IPR037256	ASC_dom_sf
IPR006828	ASC_dom
IPR032640	AMPK1_CBM
IPR014756	Ig_E-set

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0016301	kinase activity

Vocabulary: **cellular component**
Term	Definition
GO:0031588	nucleotide-activated protein kinase complex

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006828	Association with the SNF1 complex (ASC) domain	SMART	SM01010	AMPKBI_2	coord: 194..284 e-value: 1.4E-22 score: 91.1
IPR006828	Association with the SNF1 complex (ASC) domain	PFAM	PF04739	AMPKBI	coord: 217..282 e-value: 4.1E-20 score: 71.8
None	No IPR available	GENE3D	G3DSA:3.30.160.760		coord: 198..284 e-value: 2.5E-23 score: 83.7
None	No IPR available	PANTHER	PTHR10343	5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT	coord: 68..284
None	No IPR available	CDD	cd02859	E_set_AMPKbeta_like_N	coord: 81..160 e-value: 2.25719E-26 score: 96.8992
IPR032640	AMP-activated protein kinase, glycogen-binding domain	PFAM	PF16561	AMPK1_CBM	coord: 80..164 e-value: 2.0E-22 score: 79.2
IPR013783	Immunoglobulin-like fold	GENE3D	G3DSA:2.60.40.10		coord: 80..178 e-value: 3.2E-21 score: 77.1
IPR039160	5'-AMP-activated protein kinase subunit beta	PANTHER	PTHR10343:SF83	5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2	coord: 68..284
IPR014756	Immunoglobulin E-set	SUPERFAMILY	SSF81296	E set domains	coord: 80..163
IPR037256	ASC domain superfamily	SUPERFAMILY	SSF160219	AMPKBI-like	coord: 195..282

Main menu

5'-AMP-activated protein kinase subunit beta-1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Owlery

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