Innexin

Overview
NameInnexin
Smed IDSMED30012037
Length (bp)1431
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30012037) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30012037) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30012037) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30012037) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30012037

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 24

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neoblastSMED30012037h1SMcG0006773 AY067503smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30012037h1SMcG0006773 AY067503smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30012037h1SMcG0006773 AY067503smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30012037h1SMcG0006773 AY067503smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30012037h1SMcG0006774 SmedASXL_063274SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30012037h1SMcG0006774 SmedASXL_015010SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30012037h1SMcG0006774 SmedASXL_063274SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30012037h1SMcG0006774 SmedASXL_015010SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30012037h1SMcG0006773 SmedASXL_015008SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
pigment cellSMED30012037h1SMcG0006773 SmedASXL_015008SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30012037h1SMcG0006773 SmedASXL_015008SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
pigment cellSMED30012037h1SMcG0006773 SmedASXL_015008SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
gutSMED30012037h1SMcG0006773 dd_Smed_v4_3659_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30012037h1SMcG0006773 dd_Smed_v4_3659_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30012037h1SMcG0006773 dd_Smed_v4_3659_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012037h1SMcG0006773 Contig42024uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012037h1SMcG0006773 Contig42024newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30012037h1SMcG0006773 dd_Smed_v4_3659_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30012037h1SMcG0006773 dd_Smed_v4_3659_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30012037h1SMcG0006773 dd_Smed_v4_3659_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012037h1SMcG0006773 Contig42024uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30012037h1SMcG0006773 Contig42024newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pigment cellSMED30012037h1SMcG0006773 dd_Smed_v6_3659_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30012037h1SMcG0006773 dd_Smed_v6_3659_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 126.331 bits (316), Expect = 5.079e-46
Identity = 66/189 (34.92%), Postives = 115/189 (60.85%), Query Frame = 3 
Query:  648 CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLY 1214
            C+++S   ++ +YI +KILY +N+V Q+ ++  ++G R  +YG+    D++ G E   S + P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++   T  SL  W+   V    ++ F+G+YL  IE  K  +   +++F+F +LR DG+F++ +++ + G++   ++   LWN Y
Sbjct:  187 CTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375

HSP 2 Score: 77.7962 bits (190), Expect = 5.079e-46
Identity = 46/166 (27.71%), Postives = 91/166 (54.82%), Query Frame = 1 
Query:  190 GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL---------NF-DKEFK------------SVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLK-KNTIMK 618
              ++S +  + DD  DKLNY ++  +I V  IL++  QY   PIQCW P  FT+  E+Y  ++C + +TY          N+ ++E +            +++ +LF++P ++WRLL   SG ++Q ++Q A ++ +   +   ++++ IA ++++ L  K+ +M 
Sbjct:   10 SAVKSIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMS 175
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 123.635 bits (309), Expect = 3.861e-43
Identity = 65/183 (35.52%), Postives = 105/183 (57.38%), Query Frame = 3 
Query:  669 YLSSVYIIIKILYLLNVVFQLCMIQRYIGTR-YSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLY 1214
            Y+SSVYI IK L+L NV+ Q  ++  ++ T  Y  +G    YD+  G E R S   P+V LC FEI  L     +T+QCVL +NM  EKIFI LW W  ++  +TA++L+ W   LV+   +  F+           + +   + +F+  +LR DG+F++ +I+ + G+++AA V  +LW ++
Sbjct:  199 YVSSVYIFIKALHLANVILQFMLLNSFLQTSDYPMFGAHVLYDLFMGREWRDSGKFPRVTLCDFEIRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVS-------KHLDIQSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIF 374

HSP 2 Score: 70.8626 bits (172), Expect = 3.861e-43
Identity = 43/168 (25.60%), Postives = 83/168 (49.40%), Query Frame = 1 
Query:  214 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNF---------DKEFK------------SVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVV 651
            R+ DDF D+L+Y ++  ++++  +L++  QY   PI+C+ P +FT++ E+Y  ++C + +TY + F         D+E +            +V  + F IP  +WR+L   SG N   ++Q         P    K++  +A H+D     + +M Q +   ++  V
Sbjct:   22 RVDDDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRAMEQYTENYCWVQNTYWVPFQDLIPHRLDDRERRQIGYYQWVPFVLAVAALTFHIPSSVWRMLAGQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHID-----DALMYQRDHGARRHSV 184
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 123.25 bits (308), Expect = 5.335e-43
Identity = 65/183 (35.52%), Postives = 105/183 (57.38%), Query Frame = 3 
Query:  669 YLSSVYIIIKILYLLNVVFQLCMIQRYIGTR-YSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLY 1214
            Y+SSVYI IK L+L NV+ Q  ++  ++ T  Y  +G    YD+  G E R S   P+V LC FEI  L     +T+QCVL +NM  EKIFI LW W  ++  +TA++L+ W   LV+   +  F+           + +   + +F+  +LR DG+F++ +I+ + G+++AA V  +LW ++
Sbjct:  199 YVSSVYIFIKALHLANVILQFMLLNSFLQTSDYPMFGAHVLYDLFMGREWRDSGKFPRVTLCDFEIRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVS-------KHLDIQSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIF 374

HSP 2 Score: 70.8626 bits (172), Expect = 5.335e-43
Identity = 43/168 (25.60%), Postives = 83/168 (49.40%), Query Frame = 1 
Query:  214 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNF---------DKEFK------------SVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVV 651
            R+ DDF D+L+Y ++  ++++  +L++  QY   PI+C+ P +FT++ E+Y  ++C + +TY + F         D+E +            +V  + F IP  +WR+L   SG N   ++Q         P    K++  +A H+D     + +M Q +   ++  V
Sbjct:   22 RVDDDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRAMEQYTENYCWVQNTYWVPFQDLIPHRLDDRERRQIGYYQWVPFVLAVAALTFHIPSSVWRMLAGQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHID-----DALMYQRDHGARRHSV 184
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 123.25 bits (308), Expect = 5.335e-43
Identity = 65/183 (35.52%), Postives = 105/183 (57.38%), Query Frame = 3 
Query:  669 YLSSVYIIIKILYLLNVVFQLCMIQRYIGTR-YSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLY 1214
            Y+SSVYI IK L+L NV+ Q  ++  ++ T  Y  +G    YD+  G E R S   P+V LC FEI  L     +T+QCVL +NM  EKIFI LW W  ++  +TA++L+ W   LV+   +  F+           + +   + +F+  +LR DG+F++ +I+ + G+++AA V  +LW ++
Sbjct:  199 YVSSVYIFIKALHLANVILQFMLLNSFLQTSDYPMFGAHVLYDLFMGREWRDSGKFPRVTLCDFEIRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVS-------KHLDIQSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIF 374

HSP 2 Score: 70.8626 bits (172), Expect = 5.335e-43
Identity = 43/168 (25.60%), Postives = 83/168 (49.40%), Query Frame = 1 
Query:  214 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-LNF---------DKEFK------------SVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVV 651
            R+ DDF D+L+Y ++  ++++  +L++  QY   PI+C+ P +FT++ E+Y  ++C + +TY + F         D+E +            +V  + F IP  +WR+L   SG N   ++Q         P    K++  +A H+D     + +M Q +   ++  V
Sbjct:   22 RVDDDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRAMEQYTENYCWVQNTYWVPFQDLIPHRLDDRERRQIGYYQWVPFVLAVAALTFHIPSSVWRMLAGQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHID-----DALMYQRDHGARRHSV 184
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 101.293 bits (251), Expect = 1.569e-41
Identity = 56/190 (29.47%), Postives = 105/190 (55.26%), Query Frame = 3 
Query:  648 CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGX---XXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWN 1208
            C ++   Y++ +YI IK+LY  NV+ Q  ++   +G+    YG     D++   E   +   P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW +  G +T  + + W+  +      + F+ +    L        +++  ++KF  ++LR DG+F++ +IS + G++++++++  LW 
Sbjct:  242 CGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 431

HSP 2 Score: 87.8113 bits (216), Expect = 1.569e-41
Identity = 49/159 (30.82%), Postives = 83/159 (52.20%), Query Frame = 1 
Query:  214 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL-----NFDKEFKS-----------------VQGILFFIPCMIWR-LLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQ 621
            RL DDF DKLNY ++  ++    +L++  QY   PIQCW P  FT + E+Y  ++C + +TY      +  +E  S                 ++ +LF++PC++WR LL  HSG NLQ ++Q A +  +   +   +++  +A HM   ++   I +Q
Sbjct:   68 RLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQ 226
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0085350)

HSP 1 Score: 55.0694 bits (131), Expect = 7.767e-8
Identity = 34/119 (28.57%), Postives = 59/119 (49.58%), Query Frame = 3 
Query:  651 SQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDA--FYDMVKGNELRSS-DYLPKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 995
            S N+    S  Y   ++L  +NV+  + M+ +++G  +  YG D   F +M +        +  P++  C F +         +   CVL LN+  EKI+I LWFW +I+  I+ V++L
Sbjct:  175 SLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVL 293
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0330306)

HSP 1 Score: 55.0694 bits (131), Expect = 7.767e-8
Identity = 34/119 (28.57%), Postives = 59/119 (49.58%), Query Frame = 3 
Query:  651 SQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDA--FYDMVKGNELRSS-DYLPKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 995
            S N+    S  Y   ++L  +NV+  + M+ +++G  +  YG D   F +M +        +  P++  C F +         +   CVL LN+  EKI+I LWFW +I+  I+ V++L
Sbjct:  175 SLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVL 293
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0345207)

HSP 1 Score: 55.0694 bits (131), Expect = 7.767e-8
Identity = 34/119 (28.57%), Postives = 59/119 (49.58%), Query Frame = 3 
Query:  651 SQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDA--FYDMVKGNELRSS-DYLPKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 995
            S N+    S  Y   ++L  +NV+  + M+ +++G  +  YG D   F +M +        +  P++  C F +         +   CVL LN+  EKI+I LWFW +I+  I+ V++L
Sbjct:  175 SLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTDVLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVL 293
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 52.373 bits (124), Expect = 5.251e-7
Identity = 33/121 (27.27%), Postives = 60/121 (49.59%), Query Frame = 3 
Query:  657 NSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYL-------PKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 995
            N   + +  + + + L  +NV+ Q+  +  ++   +S YG     D++K  EL   + +       PKV  C F +         +   CVLPLN+  EKI++ LWFW +I+  ++ +SL+
Sbjct:  171 NRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYG----SDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 52.373 bits (124), Expect = 5.251e-7
Identity = 33/121 (27.27%), Postives = 60/121 (49.59%), Query Frame = 3 
Query:  657 NSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYL-------PKVKLCKF-EITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLL 995
            N   + +  + + + L  +NV+ Q+  +  ++   +S YG     D++K  EL   + +       PKV  C F +         +   CVLPLN+  EKI++ LWFW +I+  ++ +SL+
Sbjct:  171 NRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYG----SDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 5.239e-45
Identity = 66/189 (34.92%), Postives = 115/189 (60.85%), Query Frame = 3 
Query:  648 CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLY 1214
            C+++S   ++ +YI +KILY +N+V Q+ ++  ++G R  +YG+    D++ G E   S + P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW  ++   T  SL  W+   V    ++ F+G+YL  IE  K  +   +++F+F +LR DG+F++ +++ + G++   ++   LWN Y
Sbjct:  187 CTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375

HSP 2 Score: 77.7962 bits (190), Expect = 5.239e-45
Identity = 46/166 (27.71%), Postives = 91/166 (54.82%), Query Frame = 1 
Query:  190 GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL---------NF-DKEFK------------SVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLK-KNTIMK 618
              ++S +  + DD  DKLNY ++  +I V  IL++  QY   PIQCW P  FT+  E+Y  ++C + +TY          N+ ++E +            +++ +LF++P ++WRLL   SG ++Q ++Q A ++ +   +   ++++ IA ++++ L  K+ +M 
Sbjct:   10 SAVKSIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMS 175
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 1.829e-40
Identity = 56/190 (29.47%), Postives = 105/190 (55.26%), Query Frame = 3 
Query:  648 CSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGX---XXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWN 1208
            C ++   Y++ +YI IK+LY  NV+ Q  ++   +G+    YG     D++   E   +   P+V LC FE+  L     +T+QCVL +NMF EKIF+ LWFW +  G +T  + + W+  +      + F+ +    L        +++  ++KF  ++LR DG+F++ +IS + G++++++++  LW 
Sbjct:  310 CGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 499

HSP 2 Score: 87.8113 bits (216), Expect = 1.829e-40
Identity = 49/159 (30.82%), Postives = 83/159 (52.20%), Query Frame = 1 
Query:  214 RLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL-----NFDKEFKS-----------------VQGILFFIPCMIWR-LLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQ 621
            RL DDF DKLNY ++  ++    +L++  QY   PIQCW P  FT + E+Y  ++C + +TY      +  +E  S                 ++ +LF++PC++WR LL  HSG NLQ ++Q A +  +   +   +++  +A HM   ++   I +Q
Sbjct:  136 RLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQ 294
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q22549|INX10_CAEEL (Innexin-10 OS=Caenorhabditis elegans OX=6239 GN=inx-10 PE=3 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 4.361e-37
Identity = 65/191 (34.03%), Postives = 108/191 (56.54%), Query Frame = 3 
Query:  669 YLSSVYIIIKILYLLNVVFQLCMIQRYIGT-RYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFI----GXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELW-NLYRSQ 1223
            +++++Y+  K  YL NV  QL  + R++ T +Y +YG+ A  D++ G     S   P+V LC F++  +     +T+QCVL +N+F EKIFILLWFW + +   T  S   WL   + R   VRFI           +  ++  +  V +FI +YL++DG+F++ ++++  G I   D+V ELW N + S+
Sbjct:  194 FVTAMYLCTKFFYLANVCLQLMFMNRFLETDKYKWYGMGALVDLLNGTTWEQSGMFPRVSLCDFDVRVMGNMQEHTIQCVLVINIFNEKIFILLWFWYLALLVFTFGSFFYWLLVSLWRHLNVRFIIRHLEMSDIAFDSSEDGAQEKVNRFISNYLKSDGVFVIRMMTLQSGVIFGTDLVQELWRNFHGSE 384

HSP 2 Score: 67.3958 bits (163), Expect = 4.361e-37
Identity = 42/148 (28.38%), Postives = 77/148 (52.03%), Query Frame = 1 
Query:  226 DFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY----------LNFDKE-------------FKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLK 600
            DF D+L+  F+  L+I L +L++  Q+  KP++C  P  F+ SWE+YA ++C  SDTY          L  D++             F  ++   F +P ++W+ L  HSG  +  I++ +++ +   PD  + +IK + +H+   L+
Sbjct:   20 DFVDRLHSYFTCNLLIGLAVLVSFKQFGGKPVECLVPDIFSSSWEQYAENYCWASDTYYVPTNEPVAGLQSDEKRQRKISYYQWVPFFLLLEAACFRLPSLLWKYLAGHSGIKINEIVKLSSDPNNIKPDIKRANIKSLTVHLQGALR 167
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61787|INX16_CAEEL (Innexin-16 OS=Caenorhabditis elegans OX=6239 GN=inx-16 PE=3 SV=2)

HSP 1 Score: 100.138 bits (248), Expect = 1.596e-29
Identity = 55/191 (28.80%), Postives = 100/191 (52.36%), Query Frame = 3 
Query:  684 YIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSY 1256
            Y+++K+L LLN+V Q  ++  ++ T Y+F+G   F+DMV G   + S + P+V  C   + +L     ++LQCVL +NMF EKIFI LWFW   +   TA   + W+ +  +   K+ FI     L +   +       +   + LR DG+  + L+  N G + + +++ +++N+      +   P + +
Sbjct:  180 YLVMKLLILLNIVLQFFLLNSFLNTAYTFWGWGIFWDMVNGRHWQESGHFPRVSFCDINVRELGNIHHWSLQCVLMVNMFNEKIFIFLWFWFAFLLVATAGDFVIWVWRRFDSNSKLGFI--LDLLNQEGIDHSPQKASELYKNVLRDDGVLFLRLLDSNSGRLNSEELMKKIYNISVGHATDLNTPIEEH 368

HSP 2 Score: 51.9878 bits (123), Expect = 1.596e-29
Identity = 35/142 (24.65%), Postives = 60/142 (42.25%), Query Frame = 1 
Query:  223 DDFS-DKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----------------------NFDKEFKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAA--NNTHVSFPDQLKKSIKFI 573
            DD S D+LNY  +  ++I   +L+    Y  +P+QCWTP +F   WE +A  +C I +TY                        +      +Q + F +P   W +   +SG  +  ++ AA  N   +   D+  + +  I
Sbjct:   21 DDTSIDRLNYVVTTSILIAFSLLLFAKNYVGEPMQCWTPNQFAGGWESFAESYCFIENTYFVPMQDSNLPAAETREGREMIYYQWVPFLLVIQALFFCVPRAFWIIYPSYSGLTIADMITAARQNGKQLEGADEALEQVAMI 162
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 1.566e-25
Identity = 74/201 (36.82%), Postives = 114/201 (56.72%), Query Frame = 3 
Query:  654 QNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGT-RYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXX------XXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNE 1235
            Q S  ++S +Y+  K+LY LNV  QL ++  ++GT R+ +YG     D+V+G     S Y P+  +C FE+ ++     Y++QCVL +N+F EKIF+LLWFW VI+   + VSL+ W   LV       F+ ++L L  L          E+S V KF+  YL  DG+F++ ++S + G I A D+V  L+  Y  Q  N+
Sbjct:  192 QYSSGFISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAYDFQDKNK 392

HSP 2 Score: 66.6254 bits (161), Expect = 1.850e-10
Identity = 51/206 (24.76%), Postives = 92/206 (44.66%), Query Frame = 1 
Query:  187 IGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----------------NFDKEFKSVQGILFFI---------PCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVVVRIQEGISHRFISLLKYFIYLMLFFN 729
            +G  +    R  DD+SD+LNY  +  +++   +LI+  Q+  +PI+C  P +F  SWE+YA ++C   DTY                   D++    Q + FF+         P  +W+    HSG  +  +++ A ++     +  +K+I  +  H+   L+    M++    V K V   +    S  FIS +  F  ++ F N
Sbjct:    8 LGMAKYLSPREDDDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSALRFQANMERKKVQVHKTVTF-LNFQYSSGFISWIYLFTKVLYFLN 212
[Close]
BLAST of Innexin vs. TrEMBL
Match: Q2L6N1 (Innexin OS=Dugesia japonica OX=6161 GN=inx3 PE=2 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 1.602e-77
Identity = 88/202 (43.56%), Postives = 141/202 (69.80%), Query Frame = 3 
Query:  645 CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFK 1250
            C  +    +L+ +YI IK LYL+N++ QL +++++IGT+Y+FYGI   +D+++G+E   S   P+V  C  E  KL +   Y+LQCVLP+NMFLEKI+I LWFW+VI+G  T  SL SW+ ++ +  ++++ I  YL+L+ +L ++++   +KF   YLR+DG F++ LI+IN+GD+VA D++CE+W +YR +R  E E  K
Sbjct:  242 CLGKLQGNFLTVLYISIKFLYLINIIGQLYLMEKFIGTKYTFYGIRVLWDLMRGHEWHHSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLCSLFSWIRRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEELK 443

HSP 2 Score: 139.043 bits (349), Expect = 1.602e-77
Identity = 76/176 (43.18%), Postives = 107/176 (60.80%), Query Frame = 1 
Query:  160 EMDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL---------------------NFDKEFKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSF-PDQLKKSIKFIAIHMDKFLKKNTI 612
            +MD    WR+   G+I SNKLR  DDF D+LNY+F+ +L+ + I LI + QY  KPIQCW PQEFT+ WEEY  ++C +S+TY                       +      +Q +LF+IPC+IWR +   SGFN++RI+Q A++ + S  P+QL+KSI FIA HMD  L ++ I
Sbjct:   38 DMDATFFWRLSKLGRIGSNKLRFDDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFASIQNRMPSKDTRNEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYRHRI 213
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8GHL0 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 2.603e-72
Identity = 88/213 (41.31%), Postives = 138/213 (64.79%), Query Frame = 3 
Query:  669 YLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFK---SYDETNLSGYKFINVN 1298
            +L  +Y  IK+LYLLNV  QL +++++IGT Y+F+G     D+V G +   S   P+V  C  +  K  +   YTLQCVLPLNMFLEKI++ LWFW+V++  +T  S ++W  ++   + ++ FI +YLK++ +LK+++++  +KF+ +YLR DG+FI  LI++N GDIVA D+ CELW++YR +R  E +  K    +  T  +G    N N
Sbjct:  769 FLVVLYFFIKVLYLLNVFGQLYIMEKFIGTTYTFFGFRVLLDIVHGIKWYQSSNFPRVTFCDLQAKKEGQNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLTSFVNWFFRMAFARRRLNFIRKYLKIMNVLKDTDKTTSRKFVENYLRVDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKRLQELDDTKLEPDHRHTAFAGMNATNGN 981

HSP 2 Score: 140.198 bits (352), Expect = 2.603e-72
Identity = 74/201 (36.82%), Postives = 121/201 (60.20%), Query Frame = 1 
Query:  139 TQSRNLTEMDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----------------------NFDKEFKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVVVRIQE 666
             Q  + +EMD    W++   G+I S+KLR  DDF+D+LNY+F+ +++ + I LI + QY  KPIQCW PQEFT+ WEEYA ++C +++TY                        +     +VQ ++F++PC+IWRL + +SGFNL++I+Q A + +V  P+ L K+++F+A +M+       I +Q  R  ++GV VR++ 
Sbjct:  559 VQGGHGSEMDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVQADHLPPQHIRNELMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNLRKILQMATDANVVIPEALNKNVRFMARYME-----GCIYRQ--REYRRGVGVRLKH 752

HSP 3 Score: 56.9954 bits (136), Expect = 7.804e-14
Identity = 32/133 (24.06%), Postives = 65/133 (48.87%), Query Frame = 1 
Query:  313 KPIQCWTPQEFTKSWEEYARDFCGISDTY-----------------LNFDKEFKSV------QGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKK 642
            KPIQCW PQEF+K+WE++A ++C +S+TY                 + F   ++ V      Q I+ +IP ++WR+        L  +++ A    +   D  +K+++ +   +++  + +    ++   V+K
Sbjct:    1 KPIQCWVPQEFSKAWEDFAENYCWVSNTYFLMPEQDIPVKTEQLKQMTFITYYQWVAIVLAGQAIITWIPHLLWRV----GARRLPVLIKNARGASIPDTDLRRKAVQCLVAALEEQAEASRRYSRMKNVVEK 129

HSP 4 Score: 50.0618 bits (118), Expect = 7.804e-14
Identity = 21/77 (27.27%), Postives = 46/77 (59.74%), Query Frame = 3 
Query:  645 CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLN 875
            CC   S R L+ +++I++IL++ N + Q+ ++++++GT  +F+G +    +  G E R + + P+V  C   + K+ 
Sbjct:  132 CCLSPSMR-LTMLFLIVRILFIGNSIGQIYLMRQFLGTNDTFFGYEVLKSLTLGREWRETGHFPRVTYCHLVVRKVG 207

HSP 5 Score: 75.0998 bits (183), Expect = 1.862e-10
Identity = 46/118 (38.98%), Postives = 71/118 (60.17%), Query Frame = 3 
Query:  888 YTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECE 1241
            + LQCVLP+N F+EK+++ LWFW +I+G +T  S L W+ K +    +V FI +YLK + +L  +EE    +F+   L  DG+FI+ ++S    D++A DV   LW  YR  +    E
Sbjct:  390 FDLQCVLPINHFVEKVYVFLWFWFIILGVLTFASTLLWVFKTLIPYRRVAFIKQYLKAMRILSNTEERDCNRFVNINLGADGVFILQVVSNLASDLIALDVASTLWKNYRQAKITGTE 507
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A267EEW5 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 2.503e-71
Identity = 88/213 (41.31%), Postives = 138/213 (64.79%), Query Frame = 3 
Query:  669 YLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFK---SYDETNLSGYKFINVN 1298
            +L  +Y  IK+LYLLNV  QL +++++IGT Y+F+G     D+V G +   S   P+V  C  +  K  +   YTLQCVLPLNMFLEKI++ LWFW+V++  +T  S ++W  ++   + ++ FI +YLK++ +LK+++++  +KF+ +YLR DG+FI  LI++N GDIVA D+ CELW++YR +R  E +  K    +  T  +G    N N
Sbjct:  203 FLVVLYFFIKVLYLLNVFGQLYIMEKFIGTTYTFFGFRVLLDIVHGIKWYQSSNFPRVTFCDLQAKKEGQNYHYTLQCVLPLNMFLEKIYVFLWFWHVLVSIVTLTSFVNWFFRMAFARRRLNFIRKYLKIMNVLKDTDKTTSRKFVENYLRVDGVFIFRLIAMNCGDIVAGDLACELWSIYRHKRLQELDDTKLEPDHRHTAFAGMNATNGN 415

HSP 2 Score: 137.117 bits (344), Expect = 2.503e-71
Identity = 72/193 (37.31%), Postives = 117/193 (60.62%), Query Frame = 1 
Query:  163 MDERPSWRI---GKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----------------------NFDKEFKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVVVRIQE 666
            MD    W++   G+I S+KLR  DDF+D+LNY+F+ +++ + I LI + QY  KPIQCW PQEFT+ WEEYA ++C +++TY                        +     +VQ ++F++PC+IWRL + +SGFNL++I+Q A + +V  P+ L K+++F+A +M+       I +Q  R  ++GV VR++ 
Sbjct:    1 MDATFMWKLSKLGRIGSSKLRFDDDFADRLNYQFTGVILFLFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYAENYCWVANTYYASVQADHLPPQHIRNELMITYYQWAPIVLAVQALMFYLPCLIWRLFMNYSGFNLRKILQMATDANVVIPEALNKNVRFMARYME-----GCIYRQ--REYRRGVGVRLKH 186
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A3P8HMG7 (Innexin OS=Echinostoma caproni OX=27848 GN=inx PE=3 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 1.535e-69
Identity = 97/229 (42.36%), Postives = 149/229 (65.07%), Query Frame = 3 
Query:  585 G*IFEKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNL 1271
            G I+   +   T  S +   CC +    YL  +Y  IK+LYL N+V QL M+++++G  Y+FYG+    D++KG E   S   P+V  C FE  KL +   YTLQCVLPLNMFLEKI+I LWFW+ ++G +T  S + W  ++     +V+FI +YLK++ +L++++++   KF+ +YLR DG+F++ LI+INVGD++A D+ CELW++YR +R +E E  K  D T +
Sbjct:  131 GCIYRHTFRAGTDGSGTGWGCCGKRHGNYLVVLYFFIKVLYLTNIVGQLFMMEKFVGNNYTFYGLRVLIDLIKGREWFHSGNFPRVTFCDFEAKKLGKNHKYTLQCVLPLNMFLEKIYIFLWFWHCMVGLVTLSSFIMWFYRMGFPNRRVKFIRKYLKIMSVLRDTDKAASHKFVENYLRPDGVFLIRLIAINVGDLMAGDLACELWHIYRHKRLHEAEDQKYLDATGM 359

HSP 2 Score: 102.834 bits (255), Expect = 1.535e-69
Identity = 46/122 (37.70%), Postives = 74/122 (60.66%), Query Frame = 1 
Query:  307 FAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNF---------DKEF------------KSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNT 609
              KPIQCW PQEFT+ WEEYA ++C +S+TY            D+E              ++Q + F++PC+IWRL +  SGFN++RI+Q A +++V  P+   K+++FIA +M+  + ++T
Sbjct:   16 LGKPIQCWIPQEFTRGWEEYAENYCWVSNTYFAPIQNRLPPAPDREMLLIGYYQWAPIVMAIQAMAFYLPCLIWRLFMAQSGFNVRRILQMACDSNVLLPEHTMKNVRFIARYMEGCIYRHT 137
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A183ANF5 (Innexin OS=Echinostoma caproni OX=27848 GN=inx PE=3 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 1.561e-69
Identity = 97/229 (42.36%), Postives = 149/229 (65.07%), Query Frame = 3 
Query:  585 G*IFEKKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNL 1271
            G I+   +   T  S +   CC +    YL  +Y  IK+LYL N+V QL M+++++G  Y+FYG+    D++KG E   S   P+V  C FE  KL +   YTLQCVLPLNMFLEKI+I LWFW+ ++G +T  S + W  ++     +V+FI +YLK++ +L++++++   KF+ +YLR DG+F++ LI+INVGD++A D+ CELW++YR +R +E E  K  D T +
Sbjct:  131 GCIYRHTFRAGTDGSGTGWGCCGKRHGNYLVVLYFFIKVLYLTNIVGQLFMMEKFVGNNYTFYGLRVLIDLIKGREWFHSGNFPRVTFCDFEAKKLGKNHKYTLQCVLPLNMFLEKIYIFLWFWHCMVGLVTLSSFIMWFYRMGFPNRRVKFIRKYLKIMSVLRDTDKAASHKFVENYLRPDGVFLIRLIAINVGDLMAGDLACELWHIYRHKRLHEAEDQKYLDATGM 359

HSP 2 Score: 102.834 bits (255), Expect = 1.561e-69
Identity = 46/122 (37.70%), Postives = 74/122 (60.66%), Query Frame = 1 
Query:  307 FAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNF---------DKEF------------KSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNT 609
              KPIQCW PQEFT+ WEEYA ++C +S+TY            D+E              ++Q + F++PC+IWRL +  SGFN++RI+Q A +++V  P+   K+++FIA +M+  + ++T
Sbjct:   16 LGKPIQCWIPQEFTRGWEEYAENYCWVSNTYFAPIQNRLPPAPDREMLLIGYYQWAPIVMAIQAMAFYLPCLIWRLFMAQSGFNVRRILQMACDSNVLLPEHTMKNVRFIARYMEGCIYRHT 137
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000024134.1 (SMESG000024134.1)

HSP 1 Score: 315.849 bits (808), Expect = 4.285e-130
Identity = 166/224 (74.11%), Postives = 181/224 (80.80%), Query Frame = 3 
Query:  681 VYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNLSGYKFINVNKEICAEIPGKIDTNDDIV 1352
            VYIIIK+LYLLN++ QL ++QR+IGT YSFYGI   YD++ G     S   P+V  C F   KL +   YT+QCVLP NMFLEKIFI LWFWNVIIGCITAVSL  WLNKL+ RK K RFIG+YLKL+ L K SEES  + FIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQR NECEP KSYDETN SGYK INVNKEICAEIPGKIDTNDDI 
Sbjct:  183 VYIIIKVLYLLNIIGQLYLMQRFIGTSYSFYGIQVLYDLMTGIGWPQSGNFPRVTFCDFTAKKLGKNHIYTIQCVLPFNMFLEKIFIFLWFWNVIIGCITAVSLFCWLNKLMTRKLKFRFIGDYLKLMGLAKNSEESWKENFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRQNECEPLKSYDETNFSGYKLINVNKEICAEIPGKIDTNDDIA 406

HSP 2 Score: 169.088 bits (427), Expect = 4.285e-130
Identity = 91/162 (56.17%), Postives = 110/162 (67.90%), Query Frame = 1 
Query:  184 RIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTY-------------------LNFDKEFKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTI 612
            ++G+I SN++RL+DDFSD++NY+FS ILIIVLI L  V QYF KPIQCW PQEF+  WEEY+  +C IS TY                     +     +VQ +LFFIPCM+WRLLIL SGFNLQRIMQ A + +V  PD L+KSIKFIAIHMDK LK   I
Sbjct:    3 KLGRIGSNRIRLVDDFSDRINYQFSSILIIVLISLTGVWQYFGKPIQCWIPQEFSTGWEEYSESYCWISGTYPVNRRLPELTDKQDVQISYYQWTSIVLAVQALLFFIPCMMWRLLILQSGFNLQRIMQVAVDANVIIPDHLQKSIKFIAIHMDKCLKSKKI 164
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055266.1 (SMESG000055266.1)

HSP 1 Score: 357.451 bits (916), Expect = 9.257e-120
Identity = 189/236 (80.08%), Postives = 206/236 (87.29%), Query Frame = 3 
Query:  645 CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNLSGYKFINVNKEICAEIPGKIDTNDDIV 1352
            CC++NS  YLS VYIIIK+LYLLNVV QL ++QR+IGT YSFYGI   YD+V G E R S + P++  C F+  KL +   YTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKL+NRK K RFI +YLKL+EL+K+SEES  K FIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNLSGYKFINVNKEICAEIPGKIDTNDDIV
Sbjct:  184 CCARNSGNYLSFVYIIIKVLYLLNVVGQLYLMQRFIGTSYSFYGIQVLYDLVTGIEWRKSGHFPRITFCDFKTKKLGKNHIYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLMNRKHKFRFIRDYLKLMELVKKSEESWRKNFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFKSYDETNLSGYKFINVNKEICAEIPGKIDTNDDIV 419

HSP 2 Score: 142.124 bits (357), Expect = 1.990e-37
Identity = 75/158 (47.47%), Postives = 92/158 (58.23%), Query Frame = 1 
Query:  310 AKPIQCWTPQEFTKSWEEYARDFCGISDTYLN-FDKEFK--------------------SVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVVVRIQEGISHRFISLLKYFIYLML 720
             KPIQCW PQEFT+ WEEYA  +C ISDTY N  D+                       +VQ +LFFIPCMIWRLLIL SGFNLQRIMQ A + +   PD L+KSIKFIAIHMDK LK+  I     +A  K ++  +  G   R       F+Y+++
Sbjct:   43 GKPIQCWIPQEFTRGWEEYAESYCWISDTYFNPVDRRLPKLTDRQDVKISYYQWASIVLAVQALLFFIPCMIWRLLILQSGFNLQRIMQVAKDANAIIPDHLQKSIKFIAIHMDKCLKRKKIYGTGYKAKFKRLLSYVNGGCCARNSGNYLSFVYIII 200
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055257.1 (SMESG000055257.1)

HSP 1 Score: 276.559 bits (706), Expect = 2.148e-90
Identity = 155/209 (74.16%), Postives = 160/209 (76.56%), Query Frame = 1 
Query:  163 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKS------------------VQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVVVRIQEGISHRFISLLKYFIYLMLFFNFV 735
            MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKS                  VQGILFFIPCMIWRLLILHSGFNLQRI QAANNTHVSFPDQLKKSIKFIAIHMDKFL K    K  N   K     R     S R++S +   I ++   N V
Sbjct:    1 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRITQAANNTHVSFPDQLKKSIKFIAIHMDKFLNK----KYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVV 205

HSP 2 Score: 193.741 bits (491), Expect = 2.125e-58
Identity = 95/95 (100.00%), Postives = 95/95 (100.00%), Query Frame = 3 
Query:  600 KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 884
            KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA
Sbjct:  165 KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 259
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000055257.1 (SMESG000055257.1)

HSP 1 Score: 275.018 bits (702), Expect = 3.156e-90
Identity = 155/209 (74.16%), Postives = 159/209 (76.08%), Query Frame = 1 
Query:  163 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKS------------------VQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTIMKQLNRAVKKGVVVRIQEGISHRFISLLKYFIYLMLFFNFV 735
            MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKS                  VQGILFFIPCMIWRLLILHSGFNLQRI QAANNTHVSFPDQLKKSIKFIAIHMDKFL K    K  N   K     R     S R+I     F  +  F++ V
Sbjct:    1 MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSGSQFQTINYIQWISIVLAVQGILFFIPCMIWRLLILHSGFNLQRITQAANNTHVSFPDQLKKSIKFIAIHMDKFLNK----KYNNETTKSCSKKRCCSQNSRRYIGTRYSFYGIDAFYDMV 205

HSP 2 Score: 131.724 bits (330), Expect = 2.816e-35
Identity = 69/95 (72.63%), Postives = 69/95 (72.63%), Query Frame = 3 
Query:  600 KKYNNETTKSCSKKRCCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 884
            KKYNNETTKSCSKKRCCSQNSRRY                          IGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA
Sbjct:  165 KKYNNETTKSCSKKRCCSQNSRRY--------------------------IGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA 233
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000060499.1 (SMESG000060499.1)

HSP 1 Score: 182.956 bits (463), Expect = 1.019e-80
Identity = 89/202 (44.06%), Postives = 142/202 (70.30%), Query Frame = 3 
Query:  645 CCSQNSRRYLSSVYIIIKILYLLNVVFQLCMIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRAFYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKVRFIGXXXXXXXXXXXXXXXXXXXFIFDYLRTDGLFIMHLISINVGDIVAADVVCELWNLYRSQRHNECEPFK 1250
            C  +    +L+ +YI IKILYL+N++ QL +++++IGT+Y+FYGI   +D+++G+E   S   P+V  C  E  KL +   Y+LQCVLP+NMFLEKI+I LWFW+VI+G  T  SL SW+ ++ +  ++++ I  YL+L+ +L ++++   +KF   YLR+DG F++ LI+IN+GD+VA D++CE+W +YR +R  E E  K
Sbjct:  242 CLGKLQGNFLTVLYISIKILYLINIIGQLYLMEKFIGTKYAFYGIRVLWDLMRGHEWHYSGNFPRVTFCDLEAKKLGKNHLYSLQCVLPMNMFLEKIYIFLWFWHVIVGIATLFSLFSWIKRIGSPVNRIKMIRNYLRLMNILHDTDKGPSRKFAESYLRSDGCFLIQLIAINIGDLVAGDLICEMWQIYRHKRIQEFEELK 443

HSP 2 Score: 137.117 bits (344), Expect = 1.019e-80
Identity = 74/165 (44.85%), Postives = 105/165 (63.64%), Query Frame = 1 
Query:  184 RIGKIRSNKLRLIDDFSDKLNYKFSFXXXXXXXXXXAVNQYFAKPIQCWTPQEFTKSWEEYARDFCGISDTYL----------NFDKE-----------FKSVQGILFFIPCMIWRLLILHSGFNLQRIMQAANNTHVSF-PDQLKKSIKFIAIHMDKFLKKNTI 612
            ++G+I SNKLR  DDF D+LNY+F+ +L+ + I LI + QY  KPIQCW PQEFT+ WEEY  ++C +S+TY           +  KE              +Q +LF+IPC+IWR +   SGFN++RI+Q A++ + S  P+QL+KSI FIA HMD  L ++ I
Sbjct:   49 KLGRIGSNKLRFDDDFVDRLNYQFTGLLLFMFIGLIGIRQYVGKPIQCWIPQEFTRGWEEYTENYCWVSNTYFASIQNRMPSKDARKEQMIGYYQWAPILLGLQSLLFYIPCLIWRNVSPQSGFNVRRILQVASDANCSLIPEQLQKSISFIARHMDTCLYRHRI 213
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-95.079e-4634.92Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
inx-183.861e-4335.52Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
inx-185.335e-4335.52Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
inx-185.335e-4335.52Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
unc-71.569e-4129.47Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Inx37.767e-828.57gene:FBgn0265274 transcript:FBtr0085350[more]
Inx37.767e-828.57gene:FBgn0265274 transcript:FBtr0330306[more]
Inx37.767e-828.57gene:FBgn0265274 transcript:FBtr0345207[more]
Inx25.251e-727.27gene:FBgn0027108 transcript:FBtr0301860[more]
Inx25.251e-727.27gene:FBgn0027108 transcript:FBtr0071005[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL5.239e-4534.92Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL1.829e-4029.47Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q22549|INX10_CAEEL4.361e-3734.03Innexin-10 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|O61787|INX16_CAEEL1.596e-2928.80Innexin-16 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|Q23157|INX11_CAEEL1.566e-2536.82Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q2L6N11.602e-7743.56Innexin OS=Dugesia japonica OX=6161 GN=inx3 PE=2 S... [more]
A0A1I8GHL02.603e-7241.31Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A267EEW52.503e-7141.31Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A3P8HMG71.535e-6942.36Innexin OS=Echinostoma caproni OX=27848 GN=inx PE=... [more]
A0A183ANF51.561e-6942.36Innexin OS=Echinostoma caproni OX=27848 GN=inx PE=... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024134.14.285e-13074.11SMESG000024134.1[more]
SMESG000055266.19.257e-12080.08SMESG000055266.1[more]
SMESG000055257.12.148e-9074.16SMESG000055257.1[more]
SMESG000055257.13.156e-9074.16SMESG000055257.1[more]
SMESG000060499.11.019e-8044.06SMESG000060499.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30012037 ID=SMED30012037|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1431bp
TCATGCAAATATAAATTTATTGTGTTAGAAATTTATTATGCATTATCACT
ATTAAAACAGCTATCAAATATTTTCCAGGCCTTACAATTATCGGACAACA
GAATCTCCAATATAAAACTGATATAGAAAACTATTATCACGCAAAGTCGC
AATCTAACAGAAATGGATGAAAGACCTTCTTGGAGAATCGGGAAAATCAG
ATCCAACAAATTAAGACTTATTGATGACTTTTCTGATAAATTAAATTACA
AATTTTCTTTTATATTGATAATTGTTTTAATTATTCTGATAGCTGTGAAC
CAATACTTCGCTAAGCCAATTCAGTGTTGGACTCCTCAAGAATTTACAAA
AAGTTGGGAAGAATATGCACGAGACTTTTGCGGAATATCAGACACCTATC
TCAATTTTGATAAAGAATTTAAATCTGTTCAAGGAATTTTGTTCTTCATT
CCTTGTATGATATGGCGTTTGTTGATCTTACACTCTGGATTTAATCTTCA
ACGAATAATGCAAGCTGCTAATAACACCCATGTCAGTTTTCCTGATCAAC
TAAAAAAAAGCATTAAATTTATTGCAATTCATATGGATAAATTTTTGAAA
AAAAATACAATAATGAAACAACTAAATCGTGCAGTAAAAAAAGGTGTTGT
AGTCAGAATTCAAGAAGGTATCTCTCATCGGTTTATATCATTATTAAAAT
ACTTTATTTACTTAATGTTGTTTTTCAACTTTGTATGATTCAAAGATATA
TTGGCACACGTTATTCCTTCTATGGGATAGATGCTTTTTATGATATGGTA
AAAGGAAATGAATTGAGAAGTTCAGATTATCTTCCAAAAGTTAAACTTTG
CAAATTTGAAATAACTAAATTAAACAGAAGAGCATTCTATACTCTACAAT
GCGTATTGCCGTTGAACATGTTTCTTGAGAAAATATTCATTTTACTCTGG
TTTTGGAACGTAATAATCGGCTGTATCACCGCTGTCAGTTTGTTGAGTTG
GTTGAACAAATTAGTTAACAGAAAGGACAAAGTCCGATTCATCGGAGAAT
ATCTTAAATTGATCGAGTTGCTAAAAGAATCCGAAGAATCTTTGGTAAAA
AAGTTCATTTTCGACTACTTACGAACGGATGGATTATTTATAATGCATTT
GATATCTATCAATGTCGGGGACATTGTAGCAGCGGATGTAGTCTGCGAAT
TGTGGAATTTGTACCGCTCCCAACGACATAACGAATGTGAACCTTTTAAA
TCGTATGACGAAACAAACTTGAGTGGATACAAATTCATAAATGTTAACAA
AGAAATCTGTGCGGAAATACCGGGAAAAATTGACACAAATGATGACATTG
TTTGATTTTGTCCGGCACCCTCTTTATTATTGTTGGAATTTACTGATGAA
TTTATAAGCTTTTATTTTTTACTAACAATAC
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protein sequence of SMED30012037-orf-1

>SMED30012037-orf-1 ID=SMED30012037-orf-1|Name=SMED30012037-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=207bp
MIQRYIGTRYSFYGIDAFYDMVKGNELRSSDYLPKVKLCKFEITKLNRRA
FYTLQCVLPLNMFLEKIFILLWFWNVIIGCITAVSLLSWLNKLVNRKDKV
RFIGEYLKLIELLKESEESLVKKFIFDYLRTDGLFIMHLISINVGDIVAA
DVVCELWNLYRSQRHNECEPFKSYDETNLSGYKFINVNKEICAEIPGKID
TNDDIV*
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protein sequence of SMED30012037-orf-2

>SMED30012037-orf-2 ID=SMED30012037-orf-2|Name=SMED30012037-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=192bp
MDERPSWRIGKIRSNKLRLIDDFSDKLNYKFSFILIIVLIILIAVNQYFA
KPIQCWTPQEFTKSWEEYARDFCGISDTYLNFDKEFKSVQGILFFIPCMI
WRLLILHSGFNLQRIMQAANNTHVSFPDQLKKSIKFIAIHMDKFLKKNTI
MKQLNRAVKKGVVVRIQEGISHRFISLLKYFIYLMLFFNFV*
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Aliases
The feature 'Innexin' has the following synonyms
Synonym
Dj-inx3
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0005921gap junction
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000429neoblast
PLANA:0002075pigment cell
PLANA:0002142parenchyma
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 72..81
score: 34.0
coord: 175..189
score: 48.8
coord: 44..55
score: 38.67
IPR000990InnexinPFAMPF00876Innexincoord: 21..192
e-value: 4.2E-35
score: 121.7
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 16..192
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 16..192
score: 11.589
NoneNo IPR availableTMHMMTMhelixcoord: 88..110
NoneNo IPR availableTMHMMTMhelixcoord: 31..50
NoneNo IPR availableTMHMMTMhelixcoord: 169..191