F-box/WD repeat-containing protein 10

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            DFI  LP+H+SK I+  LD  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T++++IEERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK VL +   FLR ++ CADGKIRI+N LNG+C++V++ N R DP+L+  ++ + +++NT SN+L+  FE I W Y
Sbjct:  276 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLIEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFLNGNCMKVLKANGRGDPVLSFFIQGNRMVVNTESNVLMFQFEHIKWQY 690          

Query:  692 DFISNLPVHISKRIINFL-----------------------------DEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            DFI  LP+H+SK I++ L                             D  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T++++IEERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK VL +   FLR ++ CADGKIRI+N LNG+C++V++ N R DP+L+  ++ + +++NT SN+L+  FE I W Y
Sbjct:  276 DFIRYLPIHLSKYILSMLGCMRGFPRHLPSWPSSGVSGSIFFFPGMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLIEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFLNGNCMKVLKANGRGDPVLSFFIQGNRMVVNTESNVLMFQFEHIKWQY 719          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDW 2086
            DFI  LP+H+SK I+  LD  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T+++++EERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK VL +   FLR ++ CADGKIRI+N  NG+C++VI+ N R DP+L+  ++ +       S+ L   + P++W
Sbjct:  276 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLMEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFFNGNCMKVIKANGRGDPVLSFFIQGN-------SDHLRKTYLPVEW 681          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVS 2050
            DFI  LP+H+SK I+  LD  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T+++++EERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK VL +   FLR ++ CADGKIRI+N  NG+C++VI+ N R DP+L+  ++ + + +  +S
Sbjct:  276 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLMEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFFNGNCMKVIKANGRGDPVLSFFIQGNRISVCHIS 676          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSME-----FQF 1897
            DFI  LP+H+SK I+  LD  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T++++IEERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK V++ E     FQF
Sbjct:  276 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLIEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKMVVNTESNVLMFQF 630          

Query: 1382 TYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKI-YIGHSGTISDIDAGEE--IFASGSYDGTCKLWRYDEKNSFATM---RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGH--CIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            T+D    I +   ++++ S +  I   D    K + + + GH+G++  +   EE     SGSYD + + W  D K+   T     H+  IT + + +   VSG     +KVW++  G  +K+   H   I A R++  +I+S+     V +W  +      T  G   H  +V  + F     ++G  DG +  W+++  +  C+              +  K   +++NT SN+L+  FE I W Y
Sbjct:  411 TWDQNRVIHYSGGDLIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYW--DLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFR-HKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSG---HEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCL--------------MAFKHPKMVVNTESNVLMFQFEHIKWQY 637          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRR-EDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQI----DNFNELELINSRKVFSMDVAYQNILTKKLIIEERNI----FCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLK-------------------------------------------IYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILNG 1957
            DFISNLP H+ + I+  ++  SL  C +V   W+  +   +  + ++   ++  ++     +      F        +RD +VR                       K  Y +    D  ++L L        M V Y   L  K+I +  NI      G+Y  M  +  QS N   +  + Y+   +V+    N  I+  D++      +   + GH GS+  +++ N+                       I+SGS D ++R WD  TG+C+K                                           + +GH   ++ +D  +    S S D T K+W  D      T+  H+  I  +    +L VSG S   I++W+I +GV ++ L GH + +  IR D   I+S + D  + +W      D        C+ +   H   V  ++F   + V+   D  I IW+ L+ 
Sbjct:   27 DFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFL-----NISRDMSVR-------------------RICEKFNYDVNIKRDKLDQLIL--------MHVFYSK-LYPKIIRDIHNIDNNWKRGNYK-MTRINCQSENSKGVYCLQYDDDKIVSGLRDN-TIKIWDRKDYSCSRI---LSGHTGSVLCLQYDNR----------------------VIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDA 449          

Query: 1409 HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++D +I+SG  D +I+ WD     C +I  GH+G++  +     +  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WS  T+    T  G   H + +  ++++    V+G +D  IR+W+I +G C+RV+ G+
Sbjct:  175 YDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAG---HRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGH 369          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRR-EDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQI----DNFNELELINSRKVFSMDVAYQNILTKKLIIEERNI----FCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLK-------------------------------------------IYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILNG 1957
            DFISNLP H+ + I+  ++  SL  C +V   W+  +   +  + ++   ++  ++     +      F        +RD +VR                       K  Y +    D  ++L L        M V Y   L  K+I +  NI      G+Y  M  +  QS N   +  + Y+   +V+    N  I+  D++      +   + GH GS+  +++ N+                       I+SGS D ++R WD  TG+C+K                                           + +GH   ++ +D  +    S S D T K+W  D      T+  H+  I  +    +L VSG S   I++W+I +GV ++ L GH + +  IR D   I+S + D  + +W      D        C+ +   H   V  ++F   + V+   D  I IW+ L+ 
Sbjct:   27 DFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFL-----NISRDMSVR-------------------RICEKFNYDVNIKRDKLDQLIL--------MHVFYSK-LYPKIIRDIHNIDNNWKRGNYK-MTRINCQSENSKGVYCLQYDDDKIVSGLRDN-TIKIWDRKDYSCSRI---LSGHTGSVLCLQYDNR----------------------VIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDA 449          

Query: 1409 HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++D +I+SG  D +I+ WD     C +I  GH+G++  +     +  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WS  T+    T  G   H + +  ++++    V+G +D  IR+W+I +G C+RV+ G+
Sbjct:  175 YDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAG---HRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGH 369          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRR-EDIVNAKIKKQAMMLQ-SQKDESKSVFTAPAD-------PRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLK-------------------------------------------IYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILNG 1957
            DFISNLP H+ + I+  ++  SL  C +V   W+  +   +  + ++   ++  ++    S+K +         D        +F  D N++  +L+      ++ +   P    +D + IDN                                N   G+Y  M  +  QS N   +  + Y+   +V+    N  I+  D++      +   + GH GS+  +++ N+                       I+SGS D ++R WD  TG+C+K                                           + +GH   ++ +D  +    S S D T K+W  D      T+  H+  I  +    +L VSG S   I++W+I +GV ++ L GH + +  IR D   I+S + D  + +W      D        C+ +   H   V  ++F   + V+   D  I IW+ L+ 
Sbjct:   82 DFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFLNISRDMSVRRICEKFNYDVNIKRDKLDQLILMHVFYSKLYPKII-RDIHNIDN--------------------------------NWKRGNYK-MTRINCQSENSKGVYCLQYDDDKIVSGLRDN-TIKIWDRKDYSCSRI---LSGHTGSVLCLQYDNR----------------------VIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDA 504          

Query: 1409 HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++D +I+SG  D +I+ WD     C +I  GH+G++  +     +  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WS  T+    T  G   H + +  ++++    V+G +D  IR+W+I +G C+RV+ G+
Sbjct:  230 YDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAG---HRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGH 424          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRR-EDIVNAKIKKQAMMLQ-SQKDESKSVFTAPAD-------PRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLK-------------------------------------------IYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILNG 1957
            DFISNLP H+ + I+  ++  SL  C +V   W+  +   +  + ++   ++  ++    S+K +         D        +F  D N++  +L+      ++ +   P    +D + IDN                                N   G+Y  M  +  QS N   +  + Y+   +V+    N  I+  D++      +   + GH GS+  +++ N+                       I+SGS D ++R WD  TG+C+K                                           + +GH   ++ +D  +    S S D T K+W  D      T+  H+  I  +    +L VSG S   I++W+I +GV ++ L GH + +  IR D   I+S + D  + +W      D        C+ +   H   V  ++F   + V+   D  I IW+ L+ 
Sbjct:   82 DFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFLNISRDMSVRRICEKFNYDVNIKRDKLDQLILMHVFYSKLYPKII-RDIHNIDN--------------------------------NWKRGNYK-MTRINCQSENSKGVYCLQYDDDKIVSGLRDN-TIKIWDRKDYSCSRI---LSGHTGSVLCLQYDNR----------------------VIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDA 504          

Query: 1409 HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++D +I+SG  D +I+ WD     C +I  GH+G++  +     +  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WS  T+    T  G   H + +  ++++    V+G +D  IR+W+I +G C+RV+ G+
Sbjct:  230 YDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAG---HRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGH 424          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRR-EDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQI----DNFNELELINSRKVFSMDVAYQNILTKKLIIEERNI----FCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLK-------------------------------------------IYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILNG 1957
            DFISNLP H+ + I+  ++  SL  C +V   W+  +   +  + ++   ++  ++     +      F        +RD +VR                       K  Y +    D  ++L L        M V Y   L  K+I +  NI      G+Y  M  +  QS N   +  + Y+   +V+    N  I+  D++      +   + GH GS+  +++ N+                       I+SGS D ++R WD  TG+C+K                                           + +GH   ++ +D  +    S S D T K+W  D      T+  H+  I  +    +L VSG S   I++W+I +GV ++ L GH + +  IR D   I+S + D  + +W      D        C+ +   H   V  ++F   + V+   D  I IW+ L+ 
Sbjct:   82 DFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFL-----NISRDMSVR-------------------RICEKFNYDVNIKRDKLDQLIL--------MHVFYSK-LYPKIIRDIHNIDNNWKRGNYK-MTRINCQSENSKGVYCLQYDDDKIVSGLRDN-TIKIWDRKDYSCSRI---LSGHTGSVLCLQYDNR----------------------VIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDA 504          

Query: 1409 HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++D +I+SG  D +I+ WD     C +I  GH+G++  +     +  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WS  T+    T  G   H + +  ++++    V+G +D  IR+W+I +G C+RV+ G+
Sbjct:  230 YDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAG---HRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGH 424          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            I+SGS D +++ W    GKCL+  +GH+G +        I  SGS D T K+W  D      T++ H   +  + +     VSG     ++VW+I+ G  +  L GH   +  ++ D   I+S + D  V +W    E   C+     H   V S++F  L  V+G  D  IR+W++  G+C   + G+
Sbjct: 1008 IVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHP--ERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGH 1194          

Query: 1196 LRT-ISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHA--GSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS-TVGE-FDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            LRT + + GG+  +    N II     R ++   M +    H   G    V+ ++ H  K                   ++SGS D ++R WD   G CL + +GH   +  +    ++  SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G    +L GH    S + L    ++S + D+ V +W  T G+   T  G   H  +V  ++F     VT   DG +++W++  G  IR  V   +  S  ++  +  +DT +I  V        + ++VL+F+
Sbjct: 1028 LRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSK-------------------VVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTGDFIRNLVALDSGGSGGVVWRIRANDTKLICAVGSRNGTEETKLMVLDFD 1317          

Query: 1625 HPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            H IT +  S    VSG     +KVW+  NG  +++L GH   + + ++    I+S S D  + +W    +   C+     H  +V  M     + V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D  LI++   + +V  + P
Sbjct:  996 HVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDM--DSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAA---VRCVQYDGKLIVSGAYDYMVKIWHP 1142          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            I+SGS D +++ W    GKCL+  +GH+G +        I  SGS D T K+W  D      T++ H   +  + +     VSG     ++VW+I+ G  +  L GH   +  ++ D   I+S + D  V +W    E   C+     H   V S++F  L  V+G  D  IR+W++  G+C   + G+
Sbjct: 1008 IVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHP--ERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGH 1194          

Query: 1196 LRT-ISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHA--GSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS-TVGE-FDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            LRT + + GG+  +    N II     R ++   M +    H   G    V+ ++ H  K                   ++SGS D ++R WD   G CL + +GH   +  +    ++  SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G    +L GH    S + L    ++S + D+ V +W  T G+   T  G   H  +V  ++F     VT   DG +++W++  G  IR  V   +  S  ++  +  +DT +I  V        + ++VL+F+
Sbjct: 1028 LRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSK-------------------VVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTGDFIRNLVALDSGGSGGVVWRIRANDTKLICAVGSRNGTEETKLMVLDFD 1317          

Query: 1625 HPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            H IT +  S    VSG     +KVW+  NG  +++L GH   + + ++    I+S S D  + +W    +   C+     H  +V  M     + V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D  LI++   + +V  + P
Sbjct:  996 HVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDM--DSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAA---VRCVQYDGKLIVSGAYDYMVKIWHP 1142          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            I+SGS D +++ W    GKCL+  +GH+G +        I  SGS D T K+W  D      T++ H   +  + +     VSG     ++VW+I+ G  +  L GH   +  ++ D   I+S + D  V +W    E   C+     H   V S++F  L  V+G  D  IR+W++  G+C   + G+
Sbjct: 1008 IVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHP--ERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGH 1194          

Query: 1196 LRT-ISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHA--GSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS-TVGE-FDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            LRT + + GG+  +    N II     R ++   M +    H   G    V+ ++ H  K                   ++SGS D ++R WD   G CL + +GH   +  +    ++  SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G    +L GH    S + L    ++S + D+ V +W  T G+   T  G   H  +V  ++F     VT   DG +++W++  G  IR  V   +  S  ++  +  +DT +I  V        + ++VL+F+
Sbjct: 1028 LRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLHGSK-------------------VVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTGDFIRNLVALDSGGSGGVVWRIRANDTKLICAVGSRNGTEETKLMVLDFD 1317          

Query: 1625 HPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            H IT +  S    VSG     +KVW+  NG  +++L GH   + + ++    I+S S D  + +W    +   C+     H  +V  M     + V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D  LI++   + +V  + P
Sbjct:  996 HVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWDM--DSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAA---VRCVQYDGKLIVSGAYDYMVKIWHP 1142          

Query:  692 DFISNLPV----HISKRIINFLDEKSLNVCSKVCEIWQQIVYE-VRREDIVNAKIKKQAMM--LQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHS-HRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNK--------HNKKFFGKRTYDSYNNICHEDVEIL----------SGSYDTSIRRWDTFTGKCL---KIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILN 1954
            DFI+ LP+    HI++ I+++LD +SL     VC+ W +++ E +  + ++  K++  ++   L  +++  + +F     PR  +          PHS HR ++     P   N D   I+N                    N  T + ++  R I C           +S N   +  + Y+ G +V+    N I +  D+  +Q      ++ GH GS+  +++ +K           + +   T +  N + H    +L          + S D SI  WD  +   +   ++ +GH   ++ +D  E+   S S D T K+W         T+  HK  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W  V   D        C+     H   V  ++F   + V+   D  I IW+ LN
Sbjct:   87 DFITLLPIKGLDHIAENILSYLDAESLKSSELVCKEWLRVISEGMLWKKLIERKVRTDSLWRGLAERRNWMQYLFK----PRPGQTQ-------RPHSFHRELF-----PKIMN-DIDSIEN--------------------NWRTGRHML--RRINC-----------RSENSKGVYCLQYDDGKIVSGLRDNTI-KIWDRTDLQC---VKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWDLVAALDPRAASNTLCLNTLVEHTGRVFRLQFDEFQIVSSSHDDTILIWDFLN 491          

Query: 1349 NKHNKKFFGKRTYDSYNNIC--HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVG-EFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             +H  +    R+ +S    C  ++D +I+SG  D +I+ WD    +C+K  +GH+G++  +   +++  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WST   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  196 GRHMLRRINCRSENSKGVYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNG--HKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGH 412          

Query:  692 DFISNLPV----HISKRIINFLDEKSLNVCSKVCEIWQQIVYE-VRREDIVNAKIKKQAMM--LQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHS-HRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNK--------HNKKFFGKRTYDSYNNICHEDVEIL----------SGSYDTSIRRWDTFTGKCL---KIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILN 1954
            DFI+ LP+    HI++ I+++LD +SL     VC+ W +++ E +  + ++  K++  ++   L  +++  + +F     PR  +          PHS HR ++     P   N D   I+N                    N  T + ++  R I C           +S N   +  + Y+ G +V+    N I +  D+  +Q      ++ GH GS+  +++ +K           + +   T +  N + H    +L          + S D SI  WD  +   +   ++ +GH   ++ +D  E+   S S D T K+W         T+  HK  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W  V   D        C+     H   V  ++F   + V+   D  I IW+ LN
Sbjct:   87 DFITLLPIKGLDHIAENILSYLDAESLKSSELVCKEWLRVISEGMLWKKLIERKVRTDSLWRGLAERRNWMQYLFK----PRPGQTQ-------RPHSFHRELF-----PKIMN-DIDSIEN--------------------NWRTGRHML--RRINC-----------RSENSKGVYCLQYDDGKIVSGLRDNTI-KIWDRTDLQC---VKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWDLVAALDPRAASNTLCLNTLVEHTGRVFRLQFDEFQIVSSSHDDTILIWDFLN 491          

Query: 1349 NKHNKKFFGKRTYDSYNNIC--HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVG-EFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             +H  +    R+ +S    C  ++D +I+SG  D +I+ WD    +C+K  +GH+G++  +   +++  SGS D T ++W  +      T+  H   +  +  +  + V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WST   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  196 GRHMLRRINCRSENSKGVYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNG--HKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGH 412          

Query:  743 LDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHP--ITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            LD+ SL+ C +V + WQ +  E+  E  V  ++KKQAM+ Q          T+  +P +A+   V VP  E   H   +   SP HT ++                     +D  Y+   T+K+ +EERN++CG Y+  ++LE +    D  R + Y GG LVAV   ++ I+ L    ++   +   I+GH+GS++ V                     +C E   ++S SYD SIR W+  TG C+ I+ GH GTI+ +D   +   SG+ D   K+W          ++ KHP  I  V +SE L +S  S G I++W+IQ  + I+ +SGH   +  +  D WHILS   D  V  WS    F  C+  F HPK VL+M F FLR +TGC DGKIRI+N LNG C+RVI+ N +  P+L+L    +T+++NT  ++L+L F  + W Y
Sbjct:    6 LDKVSLSSCRRVSKHWQSLTEEILTEMEVKKRVKKQAMIFQGNS-------TSKVNPVYAKICEVLVPISEGDKH-FQHGGTSPRHTQSQGQV------------------LDSLYKGFKTEKIQLEERNVYCGVYNTSVLLERE----DGSRVMHYAGGQLVAVGSRDRTIRLLHIGSLKE--LPLVIQGHSGSVRAVL--------------------VCEEKDLVISASYDLSIRCWNLKTGMCMMIFHGHFGTINCLDLVGDRLVSGAKDCRVKVWNLQTGKCVENLKFKHPKPIMCVKMSETLVISSCSGGQIRIWSIQTALLIRQISGHQGAVLCLCFDQWHILSGGSDGVVKAWSINSSFKKCLRTFQHPKEVLAMSFLFLRIITGCMDGKIRIFNFLNGDCLRVIKTNMKQCPVLSLHTHHNTVVVNTRGSVLMLQFAEVQWDY 405          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  240 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 477          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  316 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 501          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  356 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 585          

Query: 1196 LRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR--HKH--PITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            +R + Y+G  +V+    + +++  D    +TE   ++++GH   +  ++F                      + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T++  HKH   +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  386 VRCVQYDGRRVVS-GAYDFMVKVWDP---ETETCLHTLQGHTNRVYSLQF----------------------DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNL 542          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  247 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWN--AETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 410          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  240 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 477          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  316 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 501          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  356 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 585          

Query: 1196 LRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR--HKH--PITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            +R + Y+G  +V+    + +++  D    +TE   ++++GH   +  ++F                      + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T++  HKH   +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  386 VRCVQYDGRRVVS-GAYDFMVKVWDP---ETETCLHTLQGHTNRVYSLQF----------------------DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNL 542          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  247 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWN--AETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 410          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  195 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 432          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  271 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 456          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGI-----QTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
             F  DFIS LP  ++  +++FL+ K L   ++ C  W               +I  +  +L  +K + + +     +P   +   V  P       +  YI            ++ID       + S KV      + + +   L      I  GS    + + S    +     + + GG+  +    N II     R +     +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  112 QFQRDFISLLPRELALHVLSFLEPKDLLQAAQTCRYW---------------RILAEDNLLWKEKCKEEGI----DEPLHIKRRKVIKPGFTHSPWKSAYIRQ----------HRIDTNWRRGDLKSPKVLK---GHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 540          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  202 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWN--AETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 365          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  411 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 648          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  487 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 672          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  527 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 756          

Query: 1196 LRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR--HKH--PITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            +R + Y+G  +V+    + +++  D    +TE   ++++GH   +  ++F                      + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T++  HKH   +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  557 VRCVQYDGRRVVS-GAYDFMVKVWDP---ETETCLHTLQGHTNRVYSLQF----------------------DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNL 713          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  418 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNA--ETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 581          

Query:   32 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAH------------LKLAVLSEIY-------NAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKD 2107
            M +H  + +  +E+ +  + +  +  C + P    CQ C TC L      +   L    D     F+    +     EL   L+ +L P   KD  YS SR  PSL  DL   S  +  +++  L         W+   P   +  + + LL              + + ++ E++         +  ++ +  D +   ++ +++D DP  ++          +     S    +   DFI  LPVH+SKRI+ FL++KSL  C  V + W  ++ E  ++      ++ +AM+LQ    +  S+        +A+  +V VP++    + I        +   +  YQ     E          S++ AY +  T  + +EERN+FCGSY+V+I+    +   D  R I ++GG LVAV   ++ ++  D   ++ + +   I GHAGSI+ V FL                   C E   + SG +D SIR+W   +G C++I+ GH  TI+ +D  E++  SG+ D   K+W         T +HK P+  V I E+  VSG   GL+K+W++ +   IK+L+GH   I  +  D WH++S S D + + WS +G F   +  F HPK VL MEF +LR +TGCADGKIR++N LNG C+RV+R NSR+DP+++L ++D+ ++INT ++I++  FE + W Y    +
Sbjct:    1 MKQH--RIMGMMEVCEYRLLSSPVLRCAKVPM---CQRCETCLLSRRHAQTKEWLRRASDASHRRFLFGVIRRLQSLELLQYLEKVLRPTLGKDFTYSRSRINPSLRQDLGT-SGSDRALNRRLLLQFMLETWEWLKHAPYWSKANYTLLLLQMCPPNLVHSAANLIHVLIMQEMHPHTRKAVTPMGHSRATGQDGTQGPDQAVSSD-DPSIMM----------VPTSFKSTSGVSLYKDFICCLPVHLSKRILGFLNKKSLFSCLFVSQYWYYLIKETLQDLDAERLVRNEAMILQGTSYKGVSI-------SYAKMRSVPVPKVGEGGNTI--------NAVERKFYQETKTGE----------SLEAAYIDTETTSVPLEERNLFCGSYNVLIL----TGQGDHHRVIHFDGGRLVAVGSVDRKVKLFDL--VEMKQVPPLIHGHAGSIRRV-FL-------------------CEERGFLFSGGFDLSIRQWAVESGVCMRIFHGHMKTITSLDVEEDLLVSGAKDCHVKVWNIPTGKCLRTFKHKDPVLCVRIKERYVVSGCEKGLVKLWHMDSATLIKTLTGHSGPIKCLSFDQWHLISGSADGYAIAWSMMGNFQKRLCTFRHPKEVLCMEFLYLRVITGCADGKIRVFNFLNGDCLRVMRANSRADPVMSLCIRDNRMVINTPASIMIFQFEEVSWDYSQASE 643          

Query: 1073 SMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKD 2107
            +++ AY +  T  + +EERN+FCGSY+V+I+    +   D  R I ++GG LVAV   ++ ++  D   ++ + +   I GHAGSI+ V FL                   C E   + SG +D SIR+W   +G C++I+ GH  TI+ +D  E++  SG+ D   K+W         T +HK P+  V I E+  VSG   GL+K+W++ +   IK+L+GH   I  +  D WH++S S D + + WS +G F   +  F HPK VL MEF +LR +TGCADGKIR++N LNG C+RV+R NSR+DP+++L ++D+ ++INT ++I++  FE + W Y    +
Sbjct:  179 TLEAAYIDTETTSVPLEERNLFCGSYNVLIL----TGQGDHHRVIHFDGGRLVAVGSVDRKVKLFDL--VEMKQVPPLIHGHAGSIRRV-FL-------------------CEERGFLFSGGFDLSIRQWAVESGVCMRIFHGHMKTITSLDVEEDLLVSGAKDCHVKVWNIPTGKCLRTFKHKDPVLCVRIKERYVVSGCEKGLVKLWHMDSATLIKTLTGHSGPIKCLSFDQWHLISGSADGYAIAWSMMGNFQKRLCTFRHPKEVLCMEFLYLRVITGCADGKIRVFNFLNGDCLRVMRANSRADPVMSLCIRDNRMVINTPASIMIFQFEEVSWDYSQASE 497          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  354 QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 591          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  430 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 615          

Query:  683 FAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFAR----DTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMD---VAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRT-ISYNGGLLVAVSGTNKIIQFLDKRGI-----QTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            F  DFIS LP  ++  +++FLD K L   ++ C  W+ +  +  + RE      I  + + L+ +K        +P    + R    DTN R  +L+           SP      D + I     L+   +R V   D   +   + +T K                            LRT + + GG+  +    N II     R +     +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  272 FQRDFISLLPKELALYVLSFLDPKDLLQAAQTCRYWRILAEDNLLWREKCKEDGID-EPLHLKKRKISKPGFTHSPWKSAYIRQHRIDTNWRRGELK-----------SPKVLKGHDDHVI---TCLQFCGNRIVSGSDDNTLKVWSAVTGKC---------------------------LRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 699          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  424 QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 661          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  500 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 685          

Query:  683 FAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFAR----DTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMD---VAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRT-ISYNGGLLVAVSGTNKIIQFLDKRGI-----QTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
            F  DFIS LP  ++  +++FLD K L   ++ C  W+ +  +  + RE      I  + + L+ +K        +P    + R    DTN R  +L+           SP      D + I     L+   +R V   D   +   + +T K                            LRT + + GG+  +    N II     R +     +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  342 FQRDFISLLPKELALYVLSFLDPKDLLQAAQTCRYWRILAEDNLLWREKCKEDGID-EPLHLKKRKISKPGFTHSPWKSAYIRQHRIDTNWRRGELK-----------SPKVLKGHDDHVI---TCLQFCGNRIVSGSDDNTLKVWSAVTGKC---------------------------LRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 769          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  165 QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 402          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  241 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 426          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFAR----DTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMD---VAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSG-TNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
             F  DFIS LP  ++  +++FLD K L   ++ C  W+ +  +  + RE      I  + + L+ +K        +P    + R    DTN R  +L+           SP      D + I     L+   +R V   D   +   + +T K +        G +S      SQ R+              + +SG T++ ++  +    +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:   82 QFQRDFISLLPKELALYVLSFLDPKDLLQAAQTCRYWRILAEDNLLWREKCKEDGID-EPLHLKKRKISKPGFTHSPWKSAYIRQHRIDTNWRRGELK-----------SPKVLKGHDDHVI---TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS------SQMRDN-------------IIISGSTDRTLKVWNA---ETGECIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 510          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSV---FTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            DFI +LP+H+SK I+  LD+ SLN C  V + W  +  +V+ +  +++ I+ Q  +LQ  K+E ++    +T   DP +A   ++ VP++         +++     +    +++    +  L N         AYQN  T+ + +EERN+FCG+Y++ ++ ++  +NR     I YNGG L+A+S +N+ I  LD   +QT+ +    RGHAGS++ + FL++                   ED  +LSGSYD SIR WD  TG C++I+ GH GTI+ +D  +    SG+ DG  K W  +      T +HK PI A  ISE   VS    G++KVW++      K+L+GH   +  +  + WH++S   D  VM WS VG+++ C+  F HPK VL +   +LR ++ C DGKIRI+N LNG+C++VI+ ++R DP+L+   + + ++ +T SNILV  FE + W Y
Sbjct:  281 DFIRDLPLHLSKYILRMLDKHSLNRCIFVSQHWATLAQQVKVDQSMHSFIQNQISLLQVTKEEKQAYTGSYTRGIDPNYANKVSIPVPKI---------VDDGKRSRSKNQKWKLRTKTDYNLWN---------AYQNQETQLVQMEERNVFCGTYNIRVLSDTFDQNR----IIHYNGGDLMAIS-SNRKIHLLDI--MQTKELPIEFRGHAGSVRAL-FLSE-------------------EDNILLSGSYDLSIRYWDVKTGACVRIFYGHQGTITCLDVYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAAKISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNEWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRMVAHTDSNILVFQFENVKWQY 705          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            DFI +LP+H+SK I+  LD+ SLN C  V + W  +  +V+ +  +++ I+ Q  +LQ         +T   DP +A   ++ VP++         +++     +    +++    +  L N         AYQN  T+ + +EERN+FCG+Y++ ++ ++  +NR     I YNGG L+A+S +N+ I  LD   +QT+ +    RGHAGS++ + FL++                   ED  +LSGSYD SIR WD  TG C++I+ GH GTI+ +D  +    SG+ DG  K W  +      T +HK PI A  ISE   VS    G++KVW++      K+L+GH   +  +  + WH++S   D  VM WS VG+++ C+  F HPK VL +   +LR ++ C DGKIRI+N LNG+C++VI+ ++R DP+L+   + + ++ +T SNILV  FE + W Y
Sbjct:  281 DFIRDLPLHLSKYILRMLDKHSLNRCIFVSQHWATLAQQVKVDQSMHSFIQNQISLLQGS-------YTRGIDPNYANKVSIPVPKI---------VDDGKRSRSKNQKWKLRTKTDYNLWN---------AYQNQETQLVQMEERNVFCGTYNIRVLSDTFDQNR----IIHYNGGDLMAIS-SNRKIHLLDI--MQTKELPIEFRGHAGSVRAL-FLSE-------------------EDNILLSGSYDLSIRYWDVKTGACVRIFYGHQGTITCLDVYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAAKISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNEWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRMVAHTDSNILVFQFENVKWQY 695          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLII-----NTVSNILVLNFEPIDWMY 2092
            DFI +LP+H+SK I+  LD+ SLN C  V + W  +  +V+ +  +++ I+ Q  +LQ         +T   DP +A   ++ VP++         +++     +    +++    +  L N         AYQN  T+ + +EERN+FCG+Y++ ++ ++  +NR     I YNGG L+A+S +N+ I  LD   +QT+ +    RGHAGS++ + FL++                   ED  +LSGSYD SIR WD  TG C++I+ GH GTI+ +D  +    SG+ DG  K W  +      T +HK PI A  ISE   VS    G++KVW++      K+L+GH   +  +  + WH++S   D  VM WS VG+++ C+  F HPK VL +   +LR ++ C DGKIRI+N LNG+C++VI+ ++R DP+L+   + +  ++     +T SNILV  FE + W Y
Sbjct:  281 DFIRDLPLHLSKYILRMLDKHSLNRCIFVSQHWATLAQQVKVDQSMHSFIQNQISLLQGS-------YTRGIDPNYANKVSIPVPKI---------VDDGKRSRSKNQKWKLRTKTDYNLWN---------AYQNQETQLVQMEERNVFCGTYNIRVLSDTFDQNR----IIHYNGGDLMAIS-SNRKIHLLDI--MQTKELPIEFRGHAGSVRAL-FLSE-------------------EDNILLSGSYDLSIRYWDVKTGACVRIFYGHQGTITCLDVYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAAKISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNEWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRWVVGRMVAHTDSNILVFQFENVKWQY 700          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRS 1993
            DFI +LP+H+SK I+  LD+ SLN C  V + W  +  +V+ +  +++ I+ Q  +LQ         +T   DP +A   ++ VP++         +++     +    +++    +  L N         AYQN  T+ + +EERN+FCG+Y++ ++ ++  +NR     I YNGG L+A+S +N+ I  LD   +QT+ +    RGHAGS++ + FL++                   ED  +LSGSYD SIR WD  TG C++I+ GH GTI+ +D  +    SG+ DG  K W  +      T +HK PI A  ISE   VS    G++KVW++      K+L+GH   +  +  + WH++S   D  VM WS VG+++ C+  F HPK VL +   +LR ++ C DGKIRI+N LNG+C++VI+ ++R 
Sbjct:  281 DFIRDLPLHLSKYILRMLDKHSLNRCIFVSQHWATLAQQVKVDQSMHSFIQNQISLLQGS-------YTRGIDPNYANKVSIPVPKI---------VDDGKRSRSKNQKWKLRTKTDYNLWN---------AYQNQETQLVQMEERNVFCGTYNIRVLSDTFDQNR----IIHYNGGDLMAIS-SNRKIHLLDI--MQTKELPIEFRGHAGSVRAL-FLSE-------------------EDNILLSGSYDLSIRYWDVKTGACVRIFYGHQGTITCLDVYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAAKISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNEWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARG 662          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  361 QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 598          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSR 1990
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G S+
Sbjct:  437 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSK 625          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR 1969
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR
Sbjct:  477 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 661          

Query:  683 FAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFAR----DTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMD---VAYQNILTKKLIIEERNIFCGSYSVMI---ILESQSRNRDPLRTISYNGG----LLVAVSGTNKIIQFLDKR-------------GIQTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNIC---------------HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM----RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            F  DFIS LP  ++  +++FL+ K L   ++ C  W+ +  +  + RE      I  + + ++ +K        +P    + R    DTN R  +L+           SP      D + I     L+   +R V   D   +   + +T K +        G +S  +   I+ S S +R  L+  +   G     L   + T + +   +KR              I+T    + + GH  +++ V++  +        F  + +D     C                + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T+    +H+  +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  279 FQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGID-EPLHIKRRKIIKPGFIHSPWKSAYIRQHRIDTNWRRGELK-----------SPKVLKGHDDHVI---TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDR-TLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL 663          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            DFI  LP+H+SK I+  LD  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T++++IEERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK VL +   FLR ++ CADGKIRI+N LNG+C++V++ N R DP+L+  ++ + +++NT SN+L+  FE I W Y
Sbjct:  276 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLIEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFLNGNCMKVLKANGRGDPVLSFFIQGNRMVVNTESNVLMFQFEHIKWQY 690          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSV---FTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMY 2092
            DFI +LP+H+SK I+  LD+ SLN C  V + W  +  +V+ +  +++ I+ Q  +LQ  K+E ++    +T   DP +A   ++ VP++         +++     +    +++    +  L N         AYQN  T+ + +EERN+FCG+Y++ ++ ++  +NR     I YNGG L+A+S +N+ I  LD   +QT+ +    RGHAGS++ + FL++                   ED  +LSGSYD SIR WD  TG C++I+ GH GTI+ +D  +    SG+ DG  K W  +      T +HK PI A  ISE   VS    G++KVW++      K+L+GH   +  +  + WH++S   D  VM WS VG+++ C+  F HPK VL +   +LR ++ C DGKIRI+N LNG+C++VI+ ++R DP+L+   + + ++ +T SNILV  FE + W Y
Sbjct:  281 DFIRDLPLHLSKYILRMLDKHSLNRCIFVSQHWATLAQQVKVDQSMHSFIQNQISLLQVTKEEKQAYTGSYTRGIDPNYANKVSIPVPKI---------VDDGKRSRSKNQKWKLRTKTDYNLWN---------AYQNQETQLVQMEERNVFCGTYNIRVLSDTFDQNR----IIHYNGGDLMAIS-SNRKIHLLDI--MQTKELPIEFRGHAGSVRAL-FLSE-------------------EDNILLSGSYDLSIRYWDVKTGACVRIFYGHQGTITCLDVYKNRLVSGAKDGQVKEWDIETGKCLKTFKHKDPILAAKISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNEWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRMVAHTDSNILVFQFENVKWQY 705          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVS 2050
            DFI  LP+H+SK I+  LD  +LN C+ V + W  +  +V+ +   +  I+ Q   LQ         +T   DP +A   ++ VP++         +++          +++   NE         +++  AYQN  T+++++EERN+FCG+Y+V I+ ++  +NR     I Y+GG L+AVS +N+ I  LD   IQ + +    RGHAGS++ + FL                   C E+  +LSGSYD SIR WD  +G C +I+ GH GTI+ +D  +    SG  D   K+W  D      T RHK PI A  I++   VS    GL+KVW+I     +K+LSGH   +  +  D WH+LS S D  VM WS VG+++ C+  F HPK VL +   FLR ++ CADGKIRI+N  NG+C++VI+ N R DP+L+  ++ + + +  +S
Sbjct:  276 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGS-------YTRGIDPNYANKVSIPVPKM---------VDDGKSMRVKHPKWKLRTKNE---------YNLWTAYQNEETQQVLMEERNVFCGTYNVRILSDTWDQNR----VIHYSGGDLIAVS-SNRKIHLLDI--IQVKAIPVEFRGHAGSVRAL-FL-------------------CEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFFNGNCMKVIKANGRGDPVLSFFIQGNRISVCHIS 676          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  361 QHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 598          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSR 1990
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G S+
Sbjct:  437 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSK 625          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR 1969
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR
Sbjct:  477 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 661          

Query:  683 FAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFAR----DTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMD---VAYQNILTKKLIIEERNIFCGSYSVMI---ILESQSRNRDPLRTISYNGG----LLVAVSGTNKIIQFLDKR-------------GIQTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNIC---------------HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM----RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            F  DFIS LP  ++  +++FL+ K L   ++ C  W+ +  +  + RE      I  + + ++ +K        +P    + R    DTN R  +L+           SP      D + I     L+   +R V   D   +   + +T K +        G +S  +   I+ S S +R  L+  +   G     L   + T + +   +KR              I+T    + + GH  +++ V++  +        F  + +D     C                + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T+    +H+  +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  279 FQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGID-EPLHIKRRKIIKPGFIHSPWKSAYIRQHRIDTNWRRGELK-----------SPKVLKGHDDHVI---TCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDR-TLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL 663          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  364 QHRIDTNWRRGELRSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 601          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSR 1990
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G S+
Sbjct:  440 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSK 628          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR 1969
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR
Sbjct:  480 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 664          

Query: 1196 LRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM----RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            +R + Y+G  +V+    + +++  D    +TE   ++++GH   +  ++F                      + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T+    +H+  +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  510 VRCVQYDGRRVVS-GAYDFMVKVWDP---ETETCLHTLQGHTNRVYSLQF----------------------DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL 666          

Query:  689 VDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTL 2116
            VDFI+ LPV +SK +++FL+  +L+ C  V + W+++   V RED VN ++K++ M++Q     +        +P +A+D +V VP +  HS   I  N                  E+  +N +   SM  AY    T+ +I+EERN++CG Y+V+I+    S N DP R I  +G  LV +  T++ ++FL+    + +  + +I GH+GSIK V   +K  +KF                  +LSGSYDTSIR+W   TGKCLKI+ GH  TI+ I    ++ ASGS D TCK+W  D        +HK  +TAV  S+ +C++G + G +KVW++ +G  IK L+GH   ++ IR D WHI++A  D + + WS+ G+   C+  F HPK VL +EF FLR VTG ADGKIRIWN++ G C+R++RGNSRSDPI NLV  D+ + INTV N++V NFEPI +      DYTL
Sbjct:  275 VDFIARLPVQLSKYVLSFLETTTLSNCLCVSQHWRELTEGVLREDAVNQRLKEEIMLMQGTAAHT-------CNPIYAKDIDVAVPNIRLHSWETIRTNE-----------------EVRSLNHKSEASMTNAYAGCSTRNIIMEERNVYCGPYNVLIL----SDNHDPGRVIHTDGSPLVTMGSTDRKVRFLNCETARED--EKAIAGHSGSIKCVALDSK--RKF------------------VLSGSYDTSIRKWSMETGKCLKIFHGHRDTINCIQLHGDMAASGSKDHTCKVWNIDSMECIHMFKHKDAVTAVCFSDDVCITGCAAGKVKVWDMASGKLIKRLTGHQSGVTGIRFDRWHIITAGRDGYALAWSSQGDHARCLNAFRHPKEVLCVEFMFLRVVTGAADGKIRIWNMVTGQCLRIMRGNSRSDPITNLVAIDNRITINTVKNVIVFNFEPITY------DYTL 694          

Query:  689 VDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKR-GIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPSCSLSLPENKKSQIKRNNFR---HISQRCERSRLAGNIDPRIFITPNTEG-------LEMNSKCLLSNQEFSYARSFENGNPMTRSTAWHVSPSFYKSQNHSMKPPLHKS-----------KDLVDSVEDNKFTTESRINLVKXXXXX-----XXXXXXXYGFERQDHLLI-DSDLQEIKQTLRNHIRSPPQIAAEAMPEFIKTMVSQLKTSNLTGRSVSAFSLNR 2722
            VDFI  LPVH+SK I+N LD+KS    + V   W  +V EV +E  +N +IK++ M+LQ              +PR+A D +V VP  E  SH++       P T  +D       NE          + +  Y+ + T+ +I+EERN++CG Y+V+++   +    DP R   Y+GG L+A S  N+ I F D R G         +RGHAG ++ +                     +C     +LSGSYDTS+RRWD  TGKC KIY GH GT+  +D       SGS DG+ K+W  ++  +  T++HK  ++AVAI+E   V+GD+ G +KVW++ NG  +K L GH  E++AI+ D WHIL+ S D++ +LWS +G    C+G   HPK +L  EFQF+RA+T   DG++RIWN+++ +C R++RGNSRSDPILN+      +++NT +N+L L FE ++W      DY+L   S     P  + S  +    R   H   R +R +LAG  D RI     T G       +   S      ++ S + +   G   + +     +P     ++   +P  H+             + V   E+ + TT  +         S        RR+S+ FE     +  D  L E+K+ LR  +R+P        P+F++ +   L  +    R+ S   L R
Sbjct:  440 VDFIRQLPVHLSKYIVNLLDDKSAKQAAAVSTYWSNVVDEVSKESGMNLQIKEEVMLLQG-------TLANTVNPRYASDLDVPVPNQERGSHKVRLTGE--PLTDQRDPNGHLFKNEC---------NFEAGYRGVSTRNVIMEERNVYCGPYNVLVLFSEE----DPQRVTHYSGGNLLAYSDNNRRIHFADVRTGATPAAGTQPLRGHAGPVRCLL--------------------LCEARGFLLSGSYDTSLRRWDIATGKCAKIYRGHMGTVLAVDIYLNTIVSGSADGSAKVWNLEDWKAVRTLKHKSAVSAVAINENTAVTGDAKGKVKVWDLVNGSLVKKLIGHSAEVTAIKCDHWHILTCSKDSYALLWSAIGNHAQCLGAHRHPKPILCAEFQFMRAITASEDGRVRIWNVVSRNCCRIMRGNSRSDPILNISAVGQKILVNTKTNVLALTFESVNW------DYSLETDSMP---PLIRYSSYRDAPVRWQPHGYIRAQRLQLAGAADSRIVWRHETRGRGVGETDMTDGSAAPAGMRQLSLSLASRGGVGKSPTAPGSAAPPSGLFESRVPQPKHHRQCRTASGRRSQMGEAVAGNENQQPTTPGKPTTAGKPTRSLVDQGVGERRLSWAFEHPPRPVTKDPGLAEMKRRLRAQLRAP----GADPPDFVRQLRRALHAAGERPRTESDRELRR 1090          

Query:  689 VDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKR-GIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPSCSLSLPENKKSQIKRNNFR---HISQRCERSRLAGNIDPRIFITPNTEG-------LEMNSKCLLSNQEFSYARSFENGNPMTRSTAWHVSPSFYKSQNHSMKPPLHKS-----------KDLVDSVEDNKFTTESRINLVKXXXXX-----XXXXXXXYGFERQDHLLI-DSDLQEIKQTLRNHIRSPPQIAAEAMPEFIKTMVSQLKTSNLTGRSVSAFSLNR 2722
            VDFI  LPVH+SK I+N LD+KS    + V   W  +V EV +E  +N +IK++ M+LQ              +PR+A D +V VP  E  SH++       P +  +D       NE          + +  Y+ + T+ +I+EERN++CG Y+V+++   +    DP R   Y+GG L+A S  N+ I F D R G         +RGHAG ++ +                     +C     +LSGSYDTS+RRWD  TGKC KIY GH GT+  +D       SGS DG+ K+W  ++  +  T++HK  ++AVAI+E   V+GD+ G +KVW++ NG  +K L GH  E++AI+ D WHIL+ S D++ +LWS +G    C+G   HPK +L  EFQF+RA+T   DG++RIWN+++ +C R++RGNSRSDPILN+      +++NT +N+L L FE ++W      DY+L   S     P  + S  +    R   H   R +R +LAG  D RI     T G       +   S      ++ S + +   G   + +     +P     ++   +P  H+             + V   E+ + TT  +         S        RR+S+ FE     +  D  L E+K+ LR  +R+P        P+F++ +   L  +    R+ S   L R
Sbjct:  441 VDFIRQLPVHLSKYIVNLLDDKSAKQAAAVSTYWSNVVDEVSKESGMNLQIKEEVMLLQG-------TLANTVNPRYASDLDVPVPNQERGSHKVRLTGE--PLSDQRDPNGHLFKNEC---------NFEAGYRGVSTRNVIMEERNVYCGPYNVLVLFSEE----DPQRVTHYSGGNLLAYSDNNRRIHFADVRTGATPAAGTQPLRGHAGPVRCLL--------------------LCEARGFLLSGSYDTSLRRWDIATGKCAKIYRGHMGTVLAVDIYLNTIVSGSADGSAKVWNLEDWKAVRTLKHKSAVSAVAINENTAVTGDAKGKVKVWDLVNGSLVKKLIGHSAEVTAIKCDHWHILTCSKDSYALLWSAIGNHAQCLGALRHPKPILCAEFQFMRAITASEDGRVRIWNVVSRNCCRIMRGNSRSDPILNISAVGQKILVNTKTNVLALTFESVNW------DYSLETDSMP---PLIRYSSYRDAPVRWQPHGYIRAQRLQLAGAADSRIVWRHETRGRGVGETDMTDGSAAPAGMRQLSLSLASRGGVGKSPTAPGSAAPPSGLFESRVPQPKHHRQCRTASGRRSQVGEAVAGNENQQPTTPGKPTTAGKLTRSLVDQGVGERRLSWAFEHPPRPVTKDPGLAEMKRRLRAQLRAP----GADPPDFVRQLRRALHAAEERPRTESDRELRR 1091          

Query:  689 VDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKR-GIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPSCSLSLPENKKSQIKRNNFR---HISQRCERSRLAGNIDPRIFITPNTEG-------LEMNSKCLLSNQEFSYARSFENGNPMTRSTAWHVSPSFYKSQNHSMKPPLHKS-----------KDLVDSVEDNKFTTESRINLVKXXXXX-----XXXXXXXYGFERQDHLLI-DSDLQEIKQTLRNHIRSPPQIAAEAMPEFIKTMVSQLKTSNLTGRSVSAFSLNR 2722
            VDFI  LPVH+SK I+N LD+KS    + V   W  +V EV +E  +N +IK++ M+LQ              +PR+A D +V VP  E  SH++       P +  +D       NE          + +  Y+ + T+ +I+EERN++CG Y+V+++   +    DP R   Y+GG L+A S  N+ I F D R G         +RGHAG ++ +                     +C     +LSGSYDTS+RRWD  TGKC KIY GH GT+  +D       SGS DG+ K+W  ++  +  T++HK  ++AVAI+E   V+GD+ G +KVW++ NG  +K L GH  E++AI+ D WHIL+ S D++ +LWS +G    C+G   HPK +L  EFQF+RA+T   DG++RIWN+++ +C R++RGNSRSDPILN+      +++NT +N+L L FE ++W      DY+L   S     P  + S  +    R   H   R +R +LAG  D RI     T G       +   S      ++ S + +   G   + +     +P     ++   +P  H+             + V   E+ + TT  +         S        RR+S+ FE        D  L E+K+ LR  +R+P        P+F++ +   L  +    R+ S   L R
Sbjct:  440 VDFIRQLPVHLSKYIVNLLDDKSAKQAAAVSTYWSNVVDEVSKESGMNLQIKEEVMLLQG-------TLANTVNPRYASDLDVPVPNQERGSHKVRLTGE--PLSDQRDPKGHLFKNEC---------NFEAGYRGVSTRNVIMEERNVYCGPYNVLVLFSEE----DPQRVTHYSGGNLLAYSDNNRRIHFADVRTGATPAAGTQPLRGHAGPVRCLL--------------------LCEARGFLLSGSYDTSLRRWDIATGKCAKIYRGHMGTVLAVDIYLNTIVSGSADGSAKVWNLEDWKAVRTLKHKSAVSAVAINENTAVTGDAKGKVKVWDLVNGSLVKKLIGHSAEVTAIKCDHWHILTCSKDSYALLWSAIGNHAQCLGALRHPKPILCAEFQFMRAITASEDGRVRIWNVVSRNCCRIMRGNSRSDPILNISAVGQKILVNTKTNVLALTFESVNW------DYSLETDSMP---PLIRYSSYRDAPVRWQPHGYIRAQRLQLAGAADSRIVWRHETRGRGVGETDMTDGSAAPAGMRQLSLSLASRGGVGKSPTAPGSAAPPSGLFESRVPQPKHHRQCRTASGRRSQMGEAVAGNENQQPTTPGKPTTAGKPTRSLVDQGVGERRLSWAFEHPPRPATKDPGLAEMKRRLRAQLRAP----GADPPDFVRQLRRALHAAEERPRTESDRELRR 1090          

Query:  110 CKENPNPNPCQNCITCKLV-ILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLL----AHL--------KLAVLSEIYNAISTNKDSSTDSSYTSNEI-INTDSDPVTLLQRVCKISANHIFED---------------------KHSEKNNNFAV----------------------DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPSCS--LSLPENKKSQIKRNNFRHISQRCERSRLAGNIDPRIFITPNTEGLEMNSKCLLSNQ 2302
            CK +     C  C TC L   L++      +   D+    F+    +     +L   L  +L P+  KD  Y+ +R  PSL TD +  S  +  +    +EYVT     W S      ++ F++S+     AHL        K  + SE+  A +T  D    +S  S+E  +NT+  P   L  + +   + I ED                      HS   ++                         DFI  LPVHI+K I++ LD  SL     V   W+++  EV+ E  VN +I+++ +++Q             A+P +A D +V VP ++P S+ +I  +     TT K                    S +  Y  + TKK+I+EERNI+CG+Y+VM++ +    N D  R +  +G  L+AV   ++ ++F+D  G   E     I GHAGSI+    L    K                    +LSGSYDTS+R W   TG+CLKI  GH  T++ I    +I A+G+ D  CK+W  +      T +H  P+ AVA+SE++C+SG   G +KVW + +G  IK+LSGH   I+ I+ D WHI++ S D + + WS +G    C+    HPK VL +EF +LR +TG ADG+IRIWN++ G C R++RGNSRSDPIL +V   D + +NT++N+LV+NFE ++W      DYTL        +       + ++   + +I  R +R R AG  + +I I  ++   E+N++ LL NQ
Sbjct:   61 CKSSTAFTDCGECETCLLANKLRELH-GWFHRFGDHSKKRFMLGLLRRTKSVDLLRNLVMLLQPVLNKDGTYARARTHPSLPTDSATLS-SDRAVKVDNVEYVTSSTWEWFSHSTYWTKMNFLLSMCQRCDAHLLYQLFMQAKTLLASELNIAEATEGDCCETASIKSSEYSVNTEERPDLELLSLARPDYSQIIEDPFTGEILLDKIKTCQNDAANEAHSTTASSVNTVDPLILIIPTSAKAYSGVSAHRDFIRCLPVHIAKVILSMLDMASLYNALCVSPNWRKLAEEVKHEFSVNQQIREEVLLMQGASAHG-------ANPVYANDIDVLVPNIDPGSNEVIPSSGDVIKTTFKSE-----------------MSFETGYSGVSTKKVIMEERNIYCGAYNVMVVDD----NEDANRVMHTDGSHLIAVGSKDRKVRFIDC-GTGKE-SGPVIIGHAGSIRCCYLLQDQGK--------------------VLSGSYDTSVRCWSIETGQCLKILRGHQDTVTVIAVLGDIVATGAKDNQCKIWSLESGKCRKTFKHHAPVMAVALSEEICISGCEAGKVKVWELASGNLIKTLSGHHGPITGIKFDRWHIVTGSKDGYALGWSAIGSHSRCLAALRHPKEVLCLEFVYLRVITGSADGRIRIWNLITGQCCRIMRGNSRSDPILAMVAIGDRITVNTLNNLLVMNFEKVNW------DYTLKTDHVPPLIQYGSYSDAPVRTQPYPYI--RAQRMRKAGAANSKI-INHDSSPQELNTQVLLQNQ 789          

Query:  515 EIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKD----YTLNQPSCSLSLPENKKS 2161
            EI       +DS TDS        N+  DP  ++          +     S    +   DFI  LPV ISKRI+  LD+ +L  C +V + W  +  EV  E  V   ++K+AM LQ          T+  +P +AR   V VP  E                   DT+ I         + ++V  ++  Y  + TK + +EERN+FCG ++++I+L+ +    DP R I Y+GG +VAV   ++ ++ LD   I+   +   ++GHAGS++ V                     IC E   I+S SYD SIR W+  TG+C  +  GH GTI+ +D  E++  SG+ D   K+W       +  ++  H+ P+  V IS  L +S    GL+KVW  +    +K ++GH   +  +  D WHILS   D  V+ WST   F   +  FHHPK VL++ F FLR +TGC DGKIRI+N L+G C+R+I+ ++   P+L++   D+ +++N+ S +L+L F    W Y  G        L+ P  S   PE K S
Sbjct:  250 EITYIAQKRQDSDTDS--------NSSEDPALMV----------VPGSSKSMSGVSLHRDFIGGLPVDISKRILGLLDKATLQHCKRVSQHWCYLTEEVLGEMEVKKMVEKEAMNLQGSS-------TSGVNPVYARIRKVLVPLGE----------------EEDDTHPIKTGPS----SIKEVGCLESVYTGVKTKAVELEERNVFCGDFNILILLDRE----DPSRVIHYSGGQMVAVGSKDRAVRLLDVTQIKEVPLL--MQGHAGSVRAVL--------------------ICEERGLIISASYDLSIRCWNLKTGECTMLLSGHMGTITCLDLHEDLLVSGARDCRVKVWSLQSGQCYEKLKMGHRKPVLCVKISASLVLSSCEEGLVKVWETETADLLKIITGHQGYVKCLFFDQWHILSGGADGQVLAWSTKTHFTNSLMTFHHPKEVLTLSFLFLRVITGCLDGKIRIFNFLSGDCLRIIKISTHQSPVLSIHTHDNRIVVNSSSRVLLLQFTEQRWDYSAGPKRRSWAALHPPPHSNLHPEPKSS 733          

Query:  710 PVHISKRIIN--FLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSV-MIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIIN 2041
            P HI   +++   LD+ +L  C +V + W  +  EV  E  V   ++K+AM L                 R A D +      E + + +++I+N                                           ++ER    GS++  M+I+  +    DP R I Y+GG +VAV   ++ ++ LD   I+   +   ++GHAGS++ V                     IC E   I+S SYD SIR W+  TG+C  +  GH GTI+ +D  E++  SG+ D   K+W       +  ++  H+ P+  V IS  L +S    GL+KVW  +    +K ++GH   +  +  D WHILS   D  V+ WST   F   +  FHHPK VL++ F FLR +TGC DGKIRI+N L+G C+R+I+ ++   P+L++   D+ L+  
Sbjct:  196 PTHIHNNVLSPGLLDKATLQHCKRVSQHWCYLTEEVLGEMEVKKMVEKEAMNLD-------------GGSRMAPDGHTGEQLAELNCNAVLWISNC------------------------------------------VDERKSAAGSFNPEMMIMPCRE---DPSRVIHYSGGQMVAVGSKDRAVRLLDVTQIKEVPLL--MQGHAGSVRAVL--------------------ICEERGLIISASYDLSIRCWNLKTGECTMLLSGHMGTITCLDLHEDLLVSGARDCRVKVWSLQSGQCYEKLKMGHRKPVLCVKISASLVLSSCEEGLVKVWETETADLLKIITGHQGYVKCLFFDQWHILSGGADGQVLAWSTKTHFTNSLMTFHHPKEVLTLSFLFLRVITGCLDGKIRIFNFLSGDCLRIIKISTHQSPVLSIHTHDNRLVFT 564          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +  +   T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  199 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 436          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  275 IISGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 460          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGI-----QTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
             F  DFIS LP  ++  +++FL+ K L   ++ C  W               +I  +  +L  +K   + +     +P   +   V  P       +  YI            ++ID       + S KV      + + +   L      I  GS    + + S    +     + + GG+  +    N II     R +     +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  116 QFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW---------------RILAEDNLLWREKCREEGI----DEPLHGKRRKVVKPGFSHSPWKSAYIRQ----------HRIDTNWRRGDLKSPKVLK---GHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 544          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  206 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWN--AETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 369          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      + I  SGS D T K+W  +  +   T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  441 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 678          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  517 IISGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 702          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGI-----QTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR--VIRGNSRSDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
             F  DFIS LP  ++  +++FL+ K L   ++ C  W               +I  +  +L  +K   + +     +P   +   V  P       +  YI            ++ID       + S KV      + + +   L      I  GS    + + S    +     + + GG+  +    N II     R +     +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR  V   +  S  ++  +   +T ++  V        + +LVL+F+
Sbjct:  358 QFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW---------------RILAEDNLLWREKCREEGI----DEPLHGKRRKVVKPGFSHSPWKSAYIRQ----------HRIDTNWRRGDLKSPKVLK---GHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFD 786          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  448 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNA--ETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 611          

Query: 1349 NKHNKKFFGKRTYDSYNNIC--HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWST-VGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             +HN +    R+ +S    C  ++D +I+SG  D SI+ WD  + +CLKI  GH+G++  +   E +  +GS D T ++W  +      T+  H   +  +     L V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WST   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  217 GRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKQSLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNG--HKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGH 433          

Query: 1223 LLVAVSGTNKIIQFLDKRGIQTEIMKNSIR-GHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEI----LSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDT-------CIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILN 1954
            +L   +G+   +Q+ D+R I T    +++R     S +V+  L  HN+     R  +     C +D  I    ++   D S+RR          + +GH   ++ +D  ++   S S D T K+W         T+  HK  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W      D        C+     H   V  ++F   + ++   D  I IW+ LN
Sbjct:  266 ILTGHTGSVLCLQY-DERVIVTGSSDSTVRVWDVNSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRR----------VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN 512          

Query:  692 DFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIK 1726
            D I +LPVH++K I+  LD+ SL+ C  V   W+ +V EV++E IV   ++ +AM LQ     +K V     +P +AR   V VP L  +   +I   +   H+ +              +NS    S   A Q I T+ + +EERN++C  Y+V+I+L+ +    +P R ++Y GG L A+   ++ ++ LD    + + +   IRGHAGS++ V                     +C E   +LSGSYD SIR W+  +G CL+I+ GH GT++ +    +   SG+ D   K+W         T++H+  I AV  +     SG   GL+K+W++++G  IK
Sbjct:    7 DLIRSLPVHLAKYILGILDQASLSACRHVSLHWRYLVTEVQKESIVKQVVRDEAMALQG--TSAKRV-----NPVYARLREVEVPALAENGLDLISTGDMASHSASTK------------VNS----SFSSALQGIATRVVHMEERNVYCSPYNVLIVLQKE----EPCRVVAYAGGHLAALGSIDRHVRLLDVE--RAKEVPPVIRGHAGSVRAVL--------------------VCQERGLLLSGSYDLSIRSWNMHSGACLRIFRGHQGTVTCLALHGDCLVSGAKDAHVKVWDIHTGRCLHTLKHRRCIRAVGANAGHVASGCEGGLVKLWHLESGSLIK 302          

Query: 1319 AGSIKVVKFLNKHNK------KFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             G I+  K L  H+       +F G R              I+SGS D +++ W   TGKCL+  +GH+G +        I  SGS D T K+W  D      T+  H   +  + +     VSG     ++VW+I+ G  +  L+GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W+   G C+  + G+
Sbjct:  220 CGEIRAPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRGNIIVSGSTDRTLKVWNADTGQCVHTLYGHTSTVRCMHLHGNRVVSGSRDATLRVWDIETGQCLHVLAGHVAAVRCVQYDGRRVVSGAYDYTVKVWDP--ESETCLHTLQGHTNRVYSLQFDGVHIVSGSLDTSIRVWDAETGTCLHTLVGH 433          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINT 2044
            I+SGS D +++ W+  TG+C+    GH+ T+  +        SGS D T ++W  +       +  H   +  V    +  VSG     +KVW+ ++   + +L GH   + +++ D  HI+S SLD  + +W    E  TC+      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G ++    +  +     L++ +
Sbjct:  287 IVSGSTDRTLKVWNADTGQCVHTLYGHTSTVRCMHLHGNRVVSGSRDATLRVWDIETGQCLHVLAGHVAAVRCVQYDGRRVVSGAYDYTVKVWDPESETCLHTLQGHTNRVYSLQFDGVHIVSGSLDTSIRVWDA--ETGTCLHTLVGHQSLTSGMELRDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFSRKLVVTS 493          

Query: 1280 IQTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNIC---------------HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM----RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
            I+T    + + GH  +++ V++  +        +  + +D  +  C                + V I+SGS DTSIR WD  TG CL   +GH    S ++  + I  SG+ D T K+W         T+    +H+  +T +  S KL V+    G +K+W+++ G ++++L
Sbjct:  341 IETGQCLHVLAGHVAAVRCVQYDGRRVVSGAYDYTVKVWDPESETCLHTLQGHTNRVYSLQFDGVHIVSGSLDTSIRVWDAETGTCLHTLVGHQSLTSGMELRDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFSRKLVVTSSDDGTVKLWDLRTGDFLRNL 513          

Query: 1424 ILSGSYDTSIRRWDTFTGKCL---KIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILN 1954
            +++ S D SI  WD  +   +   ++ +GH   ++ +D  ++   S S D T K+W         T+  HK  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W  V   D        C+     H   V  ++F   + V+   D  I IW+ LN
Sbjct:  362 MVTCSKDRSIAVWDLASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 550          

Query: 1349 NKHNKKFFGKRTYDSYNNIC--HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWST-VGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             +HN +    R+  S    C  ++D +I+SG  D +I+   T   K    + GH      +   +    +GS D T ++W  +      T+  H   +  +  +  L V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +W+T   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  256 GRHNLQRIQCRSESSKGVYCLQYDDEKIVSGLRDNTIKVKATIKVKA-TTHHGHLIFFMFLLYVQLYVFTGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFTNGLMVTCSKDRSIAVWDLASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNG--HKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGH 471          

Query: 1205 ISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNN------------------ICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW 1819
            + +  GL+V  S  ++ I   D        ++  + GH  ++ VV F +K+     G RT   +N                   + + D  ++SGS D +IR WD   G CL++  GH   +  I    +   SG+YDG  K+W     +  A +  + P      +  LC                   +++L  H   +  ++ D + I+S+S D+ +++W
Sbjct:  355 LRFTNGLMVTCS-KDRSIAVWDLASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-----DLVAALDPRAP------AGTLC-------------------LRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIW 546          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDI--DAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAI--SEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIR--LDSWHILSASLDNFVMLWSTVGE-----------FDTCIGNFHHPKSVLSMEFQFLRA----------VTGCADGKIRIWNILNGHCIRVIRGN 1984
            I+S S D +I+ WD  TG   +   GH+ ++ DI  D   ++ AS S D T KLW +       TM  H H +++VA   +    VS      +K+W +Q G  +K+ +GH + +  +R   D   I S S D  V +W T  +              C+       S + +E     A          ++G  D  I++W+I  G C+  + G+
Sbjct:   62 IVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDLSGKMLASCSADMTVKLWDFQSFECLRTMHGHDHNVSSVAFMPNGDHLVSASRDKTMKMWEVQTGYCVKTFTGHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKECKAELREHEHVVECVSWAPDAASPVILEATGAEAKKGGKPGPYLLSGSRDKTIKMWDISTGICVITLVGH 276          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEE--IFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLC----------------------VSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSW--HILSASLDNFVMLWSTVGEFDTCIGNF-HHPKSVLSMEFQFLR--AVTGCADGKIRIWN 1945
            ++S S D +++ W+  TG C+K + GH   +  +   ++  + AS S D T ++W    K   A +R H+H +  V+ +                          +SG     IK+W+I  G+ + +L GH   +  +        ILS + D  + +W    +   C  +   H   V S++F       +TG  D  +++W 
Sbjct:  146 LVSASRDKTMKMWEVQTGYCVKTFTGHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKECKAELREHEHVVECVSWAPDAASPVILEATGAEAKKGGKPGPYLLSGSRDKTIKMWDISTGICVITLVGHDNWVRGVLFHPGGKFILSCADDKTLRVWDYKNK--RCQKSLAAHEHFVTSLDFHKTAPYVITGSVDQSVKVWE 347          

Query: 1202 TISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDA---GEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAI--SEKLCVSGDSLGLIKVWN-IQNGVYIKSLSGHFKEISAIRLDSW--HILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSM 1885
            T   +G LLVA S    +++  +  G    +   S  GH  +++V  F++                    + + +LSGS D + R WD  TG  L  +  H   +           +F +GSYD   +++   + ++  T+ H  P+ +V    SE L  S     L+KVW+ ++ G  +  L  H K ++A+ L+     +L+ASLD  V + ST   F   + +F +P ++LS+
Sbjct:   87 TFRADGRLLVAGS-EEGVVRVFEAHG---RVPLRSFDGHKRAVRVSCFMS--------------------DGLRVLSGSDDCTARLWDVATGAQLSSFASHGDYVRSAHVCTLNPNLFITGSYDHMVRVFDVRQPDAVLTLDHGFPVESVLAFPSEGLYASAGGR-LVKVWDAVRGGHLLACLRHHHKTVTALTLNGAGDRLLTASLDRHVKVLSTT-TFKP-VHSFDYPAAILSL 295          

Query: 1388 DSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKL--CVSGDSLGLIKVWNIQNGVYIKSLSGH-----------FKEISAIRLDSW--------------------------------------HILSASLDNFVMLWSTVGEFDTCI-GNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            D    +  +D ++++GS D +IR W+  TG+C+  Y GHS ++  +D+ +++  SGS D T K+W  + +  +    H   +  V +  K   C S      I++W+I+    +K   GH            K++  +  D+                                       H+LS  LDN + LW    +   CI   F H + V  +     R ++G  DG I++W++ +G C+    G
Sbjct:  343 DGVKTLYFDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSVLSVDSYQKVIVSGSADKTVKVWHVESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQETVLDENIPYPTHLLSCGLDNTIKLWDV--KTGKCIRTQFGHVEGVWDIAADNFRIISGSHDGSIKVWDLQSGKCMHTFNG 590          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADG-KIRIWNILNGHCIRVIRGN-SRSDPILNLVVKD 2023
            + +GSYD++I  WD FTGK ++   GHS  +  +   +    +GS D T ++W Y      +T R H   + +V   +K+ VSG +   +KVW++++     +L GH + ++ ++L                               HPKS          +   C+D   IR+W+I    C++V RG+  +   I+ L +KD
Sbjct:  315 LFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYFDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSVLSVDSYQKVIVSGSADKTVKVWHVESRT-CYTLRGHTEWVNCVKL-------------------------------HPKSF---------SCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKIIPLTIKD 476          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKH------------------PITAVAISEKLCVSGDSLGLIKVW 1699
            +LS   D +I+ WD  TGKC++   GH   + DI A      SGS+DG+ K+W         T   +                   PI  V I +  C SGD  G +K++
Sbjct:  525 LLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDIAADNFRIISGSHDGSIKVWDLQSGKCMHTFNGRRLQRETQHTQTQSLGDKVAPIACVCIGDSECFSGDEFGCVKMY 634          

Query: 1619 HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTV-GEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNS 1987
            H   +  +  + +L  +G     I +W++  G  I+ LSGH   +  +  D   +++ SLD  + +W+ + GE   CI  +  H  SVLS++      V+G AD  +++W++ +  C   +RG++
Sbjct:  301 HMDGVLTLQFNYRLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYFDDRKLITGSLDKTIRVWNYITGE---CISTYRGHSDSVLSVDSYQKVIVSGSADKTVKVWHVESRTCY-TLRGHT 421          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHP-ITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKS--VLSME-FQFLRAVTGCADGKIRIWN 1945
            ++SGS D +IR+WD  +GKCL+          D+     +  S + D +        K++  T R++ P I A+   +    +G   G++++W++++G  I++L GH   I++++ DS  +++ S D  V +W    +  T + N  H  S  VLS++ FQ   AV    +  ++I++
Sbjct:  515 LVSGSQDRTIRQWDLRSGKCLQTI--------DLSFANVLTTSTNVDLS--------KSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKFDSACLVTGSYDRTVRIW----DLRTGLLNKFHAYSAPVLSLDLFQENAAVVVADEPSVQIYD 672          

Query: 1385 YDSYNNICH--EDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGE--EIFASGSYDGTCKLW---RYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGL-IKVWNIQNGVYIKSLSGHFKEISAIRLDSWH--ILSASLDNFVMLWSTVG 1831
            +DS N++ +  +   +++ S D  I+ WD  +G CL  +  H+ +++ +   +  ++  S S DGT + W   RY    +F  T R +    AV  S ++  +G      I VW++Q G  + +LSGH   +S +     +  + SAS D  + +WS  G
Sbjct:  345 FDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFG 504          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLK-IYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNI 1948
            ++SGS D  I  WD  TGKC++ + +  + T SDI    ++ A    +G C L       + A M     I A+        +G   G++++W+++ G  ++ L GH   I++++ DS  +++ S+DN V +W       + +    +   V S++F       G  +G + ++N+
Sbjct:  437 LVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDI----KMPARSLNNGACLL------GTEAPM-----IGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDL--RTSSILDVIAYDLPVSSLDFDGKLITVGANEGGVNVFNM 595          

Query: 1616 RHKHPITAVAISEK---LCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWH---ILSASLDNFVMLW------------STVGE-----FDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR 1969
             H + ITA+        LC S     ++KVW++ +G+ +  L GH   ++ +++D  +   +++ S D  + LW            S + E        CI NF  H   + ++ F     V+G  D KI  W++  G CI+
Sbjct:  317 EHGNSITALDFDTPWGTLCSSSYQDRIVKVWDLNHGIQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHSPLKEKTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWDLTTGKCIQ 458          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQ 1708
            + +G+ D  +R WD   GK +++  GH+  I+ +    E   +GS D + ++W     +    + +  P++++    KL   G + G + V+N++
Sbjct:  502 LATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIAYDLPVSSLDFDGKLITVGANEGGVNVFNME 596          

Query: 1427 LSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEE--IFASGSYDGTCKLWRYDEKNSFATMRHKH--PITAVAI--SEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIR---LDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSV--LSMEFQFLRAVTGCADGKIRIWNILNGHCI 1966
            ++GS DT+++ WD  TGK      GH  T+ D+   +      S S D T K W   EKN      + H   +  V+I  +  L  +     +IK+W+++  + + +L GH   I+ ++   +D   ++S+S D  V LW  V    T     HH +SV   ++  +     + C D  IR W +  G  +
Sbjct:  156 ITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDL-EKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDP-QVVSSSTDATVRLWDVVAG-KTMKVLTHHKRSVRATALHPKEFSVASACTD-DIRSWGLAEGSLL 342          

Query: 1544 FASGSYDGTCKLWRYDEKNSFATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRI 1939
             ASGS D + K+W ++      T RH+H +  V++S+ L +SG   G +KVW+I++    KSL GH   I+ ++ D++H+++ S D + M WS +G    C+  F HPK VL +EF + R +TG ADGK+ +
Sbjct:    3 LASGSRDKSVKVWNFETGKCRRTFRHRHVVQTVSVSDALVISGCEGGKVKVWDIESATLQKSLDGHHGAITCVKFDAYHVITGSTDCYAMAWSVIGSHKKCLQAFRHPKEVLCLEFLYCRVITGSADGKVSL 134          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSR 1990
            I+SGS D +++ W+  TG C+    GH+ T+  +D  EE+  SGS DGT ++W     N    +  H   +  V       VSG    L+KVW+ +    I +L GH   + +++ D  +I+S SLD  + +W    E   C+      +S+ S ME +    V+G AD  ++IW+I  G C++ + G ++
Sbjct:  344 IVSGSTDRTLKVWNAETGYCMHTLYGHTSTVRCMDMHEEVVVSGSRDGTLRVWDTTTGNCLHVLVGHLAAVRCVKYDGHRVVSGAYDFLVKVWDPETEQCIHTLQGHTNRVYSLQFDGTYIVSGSLDTSIRVWH--AETGQCLHTLVGHQSLTSGMELRNNTLVSGNADSTVKIWDITTGQCLQTLAGPNK 532          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++SGS D +++ W   +GKCL+   GH+G +        I  SGS D T K+W  +      T+  H   +  + + E++ VSG   G ++VW+   G  +  L GH   +  ++ D   ++S + D  V +W    E + CI     H   V S++F     V+G  D  IR+W+   G C+  + G+
Sbjct:  304 VVSGSDDGTLKVWSALSGKCLRTLTGHTGGVWSSQLSGHIIVSGSTDRTLKVWNAETGYCMHTLYGHTSTVRCMDMHEEVVVSGSRDGTLRVWDTTTGNCLHVLVGHLAAVRCVKYDGHRVVSGAYDFLVKVWDP--ETEQCIHTLQGHTNRVYSLQFDGTYIVSGSLDTSIRVWHAETGQCLHTLVGH 490          

Query: 1625 HPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            H IT +  S    VSG   G +KVW+  +G  +++L+GH   + + +L    I+S S D  + +W+   E   C+   + H  +V  M+      V+G  DG +R+W+   G+C+ V+ G+  +   +  V  D   +++   + LV  ++P
Sbjct:  292 HVITCLQFSGSRVVSGSDDGTLKVWSALSGKCLRTLTGHTGGVWSSQLSGHIIVSGSTDRTLKVWN--AETGYCMHTLYGHTSTVRCMDMHEEVVVSGSRDGTLRVWDTTTGNCLHVLVGHLAA---VRCVKYDGHRVVSGAYDFLVKVWDP 438          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSG---HFKEISAIRLDSWHILSASLDNFVMLWS-TVGEF 1837
            ++SG+YD  ++ WD  T +C+    GH+  +  +        SGS D + ++W  +      T+  H+   + + +     VSG++   +K+W+I  G  +++L+G   H   ++ ++  S  ++++S D  V +W    GEF
Sbjct:  424 VVSGAYDFLVKVWDPETEQCIHTLQGHTNRVYSLQFDGTYIVSGSLDTSIRVWHAETGQCLHTLVGHQSLTSGMELRNNTLVSGNADSTVKIWDITTGQCLQTLAGPNKHQSAVTCLQFSSKFVITSSDDGTVKIWDLQTGEF 566          

Query: 1409 HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWST-VGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            ++D +I+SG  D +I+ WD  +  C+K+  GH+G++  +   E +  +GS D T ++W     +   T+  H   +  +   E + V+      I VW++Q+   I   + L GH   ++ +  D  +I+SAS D  + +WST   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  172 YDDHKIVSGLRDNTIKVWDKKSLACVKVLTGHTGSVLCLQYDENVIVTGSSDSTVRVWNVHAGDMLNTLIHHCEAVLHLRFQEGMMVTCSKDRSIAVWDMQSPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNG--HRRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGH 366          

Query:  611 LLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPV----HISKRIINFLDEKSLNVCSKVCEIWQQIVYE-VRREDIVNAKIKKQAMM--LQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKF--------LNKHNKKFFGKRTYDSYNNICH----------EDVEILSGSYDTSIRRWDTFTGKCL---KIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFD-------TCIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNIL 1951
            LL R+C     H+    ++        DFI+ LP     HI++ I++FLD KSL     VC+ W +++ + +  + ++  K++   +   L  ++   + +F +            +VP               PP+         D F +L              Y  I+ + L   E N  CG++++  I   +S N   +  + Y+   +V+    N I +  DK+ +        + GH GS+  +++         +    + +     D  N + H          ++  +++ S D SI  WD  +   +   ++ +GH   ++ +D  ++   S S D T K+W         T+  H+  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W      D        C+     H   V  ++F   + V+   D  I IW+ L
Sbjct:   19 LLSRMCHFQHGHV----NAFLKPMLQRDFITALPAKGLDHIAENILSFLDAKSLCAAEVVCKEWHRVIADGMLWKKLIERKVRTDPLWHGLSERRGWGQYLFKS------------KVP--------------DPPNN--------DFFRKL--------------YPKII-QDLETIETNWRCGNHALHKI-PCRSENSKGVYCLQYDDHKIVSGLRDNTI-KVWDKKSLAC---VKVLTGHTGSVLCLQYDENVIVTGSSDSTVRVWNVHAGDMLNTLIHHCEAVLHLRFQEGMMVTCSKDRSIAVWDMQSPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHRRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPAGTLCLRTLVEHTGRVFRLQFDDFQIVSSSHDDTILIWDFL 444          

Query: 1427 LSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDID----AGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCV--SGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDS--WHILSASLDNFVMLWSTVG--EFDTCIGNFHHPKSVLSMEFQFLRA--VTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVS 2050
            ++GSYD + + WDT +G+      GH   +  I      G++I A+GS+D TCKLW  +    + T R H   I  +A + +  V  +G      K+W++Q G  I +LSGH  EI +   +S    +L+ S D+ V +W T       T IG   H   + + +F F  +  VTG  D   +IW+   G CI  +RG+   D +L++       +I T S
Sbjct:  108 ITGSYDRTCKVWDTASGEETLTLEGHKNVVYAIAFNNPYGDKI-ATGSFDKTCKLWNAETGKCYHTYRGHSAEIVCLAFNPQSTVIATGSMDTTAKLWDVQTGAEISTLSGHSAEIISCAFNSTGTQLLTGSFDHTVSVWDTRSGRRVHTLIG---HRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGKCIGTLRGH--DDEVLDVAFDYTGQLIATAS 322          

Query: 1421 EILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDI--DAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAI--SEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEIS--AIRLDSWHILSASLDNFVMLW-STVGEFDTCIGNFH-HPKSVLSMEFQFLRAV--TGCADGKIRIWNILNGHCIRVIRGN 1984
            +I +GS+D + + W+  TGKC   Y GHS  I  +  +    + A+GS D T KLW        +T+  H   I + A   +    ++G     + VW+ ++G  + +L GH  EIS      D   I++ S+D    +W +  G+   CIG    H   VL + F +   +  T  ADG  R++N L  HC+  + G+
Sbjct:  149 KIATGSFDKTCKLWNAETGKCYHTYRGHSAEIVCLAFNPQSTVIATGSMDTTAKLWDVQTGAEISTLSGHSAEIISCAFNSTGTQLLTGSFDHTVSVWDTRSGRRVHTLIGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGK---CIGTLRGHDDEVLDVAFDYTGQLIATASADGTGRVYNALTHHCLSKLEGH 344          

Query: 1418 VEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEE--IFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAI--SEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSW--HILSASLDNFVMLWS-TVGEFDTCIGNFH-HPKSVLSMEFQFLR--AVTGCADGKIRIW 1942
             ++L+GS+D ++  WDT +G+ +   IGH G IS+     +     +GS D TCK+W         T+R H   +  VA   + +L  +  + G  +V+N      +  L GH  EIS I  ++    +L+AS D    LW    G+   C+     H   + S  F +     +TG  D   R+W
Sbjct:  232 TQLLTGSFDHTVSVWDTRSGRRVHTLIGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGKCIGTLRGHDDEVLDVAFDYTGQLIATASADGTGRVYNALTHHCLSKLEGHEGEISKITFNAQGTRLLTASSDKTARLWDPNTGK---CLQVLEGHTDEIFSCAFNYDGDIIITGSKDNTCRLW 414          

Query:  986 NSPPHT-TNKDTYQIDNFNELELINSRKVFSMDVAYQNIL-TKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNK--------------HNKKFFGKRTYDSYNN------ICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNI 1948
             +P H  +   TY I ++  L L + +     D   +  L  +  +++  N+  G   V++ L+   R               V    +++ I+  D R  ++      ++GH G ++ ++F N+              H  KF   R +  Y +      +  ++  ++SGS+D++IR WD  T +C+ +  GH G +S ++       SGS D T KLW  +  +   T+R H   +T+V +  +L +SG + G+I  W++ +G    ++  H   + ++   + H  SA  DN +  W  VG   TC+     H   V  +       +    DG +RIW++
Sbjct:   93 TNPAHIYSTVHTYCILSYVALGLAHCKHQSLFDKEEELALDVRPALVQAANVLKGHMDVVLCLQFDRRR--------------VVTGSSDRTIRMWDVRSGRS---IRKMKGHKGGVRCLQFDNERIISGSWDMTIMVWHIVKF--TRLHVLYGHKGCVSCLRFDENTLVSGSHDSTIRVWDMRTWECVLVLQGHEGAVSCLEFDAPFVLSGSADKTIKLWNVESGDCLNTLRGHADAVTSVKVIGELILSGSADGMILFWDLDSGHCEAAIQAHEGPVHSLSYANDHFFSAGGDNMIKEWD-VGTC-TCLRTLQGHRGPVQDVMVGHHYILVEHYDGSVRIWDL 416          

Query: 1421 EILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDD 2026
             +++GS D +IR WD  +G+ ++   GH G +  +    E   SGS+D T  +W   +      +  HK  ++ +   E   VSG     I+VW+++    +  L GH   +S +  D+  +LS S D  + LW+   E   C+     H  +V S++      ++G ADG I  W++ +GHC   I+ +    P+ +L   +D
Sbjct:  161 RVVTGSSDRTIRMWDVRSGRSIRKMKGHKGGVRCLQFDNERIISGSWDMTIMVWHIVKFTRLHVLYGHKGCVSCLRFDENTLVSGSHDSTIRVWDMRTWECVLVLQGHEGAVSCLEFDAPFVLSGSADKTIKLWNV--ESGDCLNTLRGHADAVTSVKVIGELILSGSADGMILFWDLDSGHCEAAIQAH--EGPVHSLSYAND 360          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      E I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  429 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRENIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 666          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  505 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 690          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR 1969
            ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR
Sbjct:  545 VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 729          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFT-APADPRFAR----DTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMD---VAYQNILTKKLIIEERNIFCGSYSVMI---ILESQSRNRDPLRTISYNGG----LLVAVSGTNKIIQFLDKR-------------GIQTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNIC---------------HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR--HKH--PITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSL 1732
             F  DFIS LP  ++  +++FL+ K L   ++ C  W+ +  +  + RE      I +   +   ++   K+ FT +P    + R    DTN R   L+           SP      D + I     L+   +R V   D   +   + +T K +        G +S  +   I+ S S +R  L+  +   G     L   + T + +   +KR              I+T    + + GH  +++ V++  +        F  + +D     C                + + ++SGS DTSIR WD  TG C+    GH    S ++  + I  SG+ D T K+W         T++  HKH   +T +  ++   ++    G +K+W+++ G +I++L
Sbjct:  346 QFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCREEGIDEP--LAPKKRGNVKAGFTHSPWKSAYIRQHRIDTNWRRGDLK-----------SPKVLKGHDDHVITC---LQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRENIIISGSTDRT-LKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNL 731          

Query: 1580 WRYDEKNSFATMR--HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  436 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRENIIISGSTDRTLKVWNA--ETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 599          

Query: 1283 QTEIMKNSIRGHAGSIKVVKFLNKH---NKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLI 2035
            Q  I  N  RG   S KV+K  + H     +F G R              I+SGS D +++ W   TGKCL+  +GH+G +      E I  SGS D T K+W  +      T+  H   +  + + EK  VSG     ++VW+I+ G  +  L GH   +  ++ D   ++S + D  V +W    E +TC+     H   V S++F  +  V+G  D  IR+W++  G+CI  + G+      + L  KD+ L+
Sbjct:  204 QHRIDTNWRRGDLKSPKVLKGHDDHVITCLQFCGNR--------------IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRENIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDP--ETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL--KDNILV 441          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSF-ATMRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            I+SGS D +++ W+  TG+C+    GH+ T+  +   E+   SGS D T ++W  +        M H   +  V    +  VSG    ++KVW+ +    + +L GH   + +++ D  H++S SLD  + +W    E   CI      +S+ S ME +    V+G AD  ++IW+I  G C++ ++G
Sbjct:  280 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDV--ETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQG 465          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGI-----QTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLW--STVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR 1969
             F  DFIS LP  ++  +++FL+ K L   ++ C  W               +I  +  +L  +K   + +   P  P+  +  NV+               +SP  +     ++ID       + S KV      + + +   L      I  GS    + + S    +     + + GG+  +    N II     R +     +T    +++ GH  +++ +     H K+                   ++SGS D ++R WD  TG+CL + +GH   +  +        SG+YD   K+W  + +    T++ H + + ++       VSG     I+VW+++ G  I +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     +T   DG +++W++  G  IR
Sbjct:  121 QFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW---------------RILAEDNLLWREKCREEGI-DEPLAPK--KRGNVKAG-----------FTHSPWKSAYIRQHRIDTNWRRGDLKSPKVLK---GHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRENIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL---HEKR-------------------VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIR 504          

Query: 1580 WRYDEKNSFATMRH--KHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEP 2077
            WR  +  S   ++    H IT +       VSG     +KVW+   G  +++L GH   + + ++    I+S S D  + +W+   E   CI   + H  +V  M     R V+G  D  +R+W+I  G C+ V+ G+  +   +  V  D   +++   + +V  ++P
Sbjct:  211 WRRGDLKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRENIIISGSTDRTLKVWN--AETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAA---VRCVQYDGRRVVSGAYDFMVKVWDP 374          

Query: 1349 NKHNKKFFGKRTYDSYNNIC--HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWST-VGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             +HN +    R+ +S    C  ++D +I+SG  D SI+ WD  T +CLKI  GH+G++  +   E +  +GS D T ++W         T+  H   +  +  +  L V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WST   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  211 GRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWEVTTGEVLNTLIHHNEAVLHLRFANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNG--HKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGH 427          

Query: 1124 ERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNK--------HNKKFFGKRTYDSYNNICHEDVEIL----------SGSYDTSIRRWDTFTGKCL---KIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDT-------CIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILN 1954
            E N  CG +++  I + +S N   +  + Y+   +++    N I +  DK+ +  E +K  + GH GS+  +++  +           + +   T +  N + H +  +L          + S D SI  WD  +   +   ++ +GH   ++ +D  ++   S S D T K+W         T+  HK  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W      D        C+     H   V  ++F   + ++   D  I IW+ LN
Sbjct:  205 EANWRCGRHNLQRI-QCRSENSKGVYCLQYDDEKIISGLRDNSI-KIWDKQTL--ECLK-ILTGHTGSVLCLQYDERVIVTGSSDSTVRVWEVTTGEVLNTLIHHNEAVLHLRFANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN 506          

Query: 1349 NKHNKKFFGKRTYDSYNNIC--HEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYI---KSLSGHFKEISAIRLDSWHILSASLDNFVMLWST-VGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
             +HN +    R+ +S    C  ++D +I+SG  D SI+ WD  T +CLKI  GH+G++  +   E +  +GS D T ++W         T+  H   +  +  +  L V+      I VW++ +   I   + L GH   ++ +  D  +I+SAS D  + +WST   EF   +    H + +  ++++    V+G +D  IR+W+I  G C+RV+ G+
Sbjct:  246 GRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWEVTTGEVLNTLIHHNEAVLHLRFANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNG--HKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGH 462          

Query: 1124 ERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNK--------HNKKFFGKRTYDSYNNICHEDVEIL----------SGSYDTSIRRWDTFTGKCL---KIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDT-------CIGNF-HHPKSVLSMEFQFLRAVTGCADGKIRIWNILN 1954
            E N  CG +++  I + +S N   +  + Y+   +++    N I +  DK+ +  E +K  + GH GS+  +++  +           + +   T +  N + H +  +L          + S D SI  WD  +   +   ++ +GH   ++ +D  ++   S S D T K+W         T+  HK  I  +   ++L VSG S   I++W+I+ G  ++ L GH + +  IR D+  I+S + D  + +W      D        C+     H   V  ++F   + ++   D  I IW+ LN
Sbjct:  240 EANWRCGRHNLQRI-QCRSENSKGVYCLQYDDEKIISGLRDNSI-KIWDKQTL--ECLK-ILTGHTGSVLCLQYDERVIVTGSSDSTVRVWEVTTGEVLNTLIHHNEAVLHLRFANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN 541          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATM-RHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFH-HPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGN 1984
            I+SGS D +++ W   TGKCL+   GH+G +           SGS D T ++W  +      T+  H   +  + +     VSG     ++VWN+  G     L+GH   +  ++ D   ++S   D  V +W    E + C+     H   V S++F     V+G  D  IR+W+   G C+  + G+
Sbjct:  239 IVSGSDDNTLKVWSAVTGKCLQTLTGHTGGVWCSQMAVATVISGSTDRTLRVWDAESGECVHTLYGHTSTVRCMHLHGNRVVSGSRDTTLRVWNVTTGQCEHVLTGHVAAVRCVQYDGRRVVSGGYDYMVKVWDP--ETEVCLHTLQGHTNRVYSLQFDGAFVVSGSLDTSIRVWDAETGGCVHTLTGH 425          

Query: 1424 ILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLS-MEFQFLRAVTGCADGKIRIWNILNGHCIRVIRG 1981
            ++SGS D ++R WD  +G+C+    GH+ T+  +        SGS D T ++W          +  H   +  V    +  VSG    ++KVW+ +  V + +L GH   + +++ D   ++S SLD  + +W    E   C+      +S+ S ME +    V+G AD  +R+W+I  G C+  ++G
Sbjct:  279 VISGSTDRTLRVWDAESGECVHTLYGHTSTVRCMHLHGNRVVSGSRDTTLRVWNVTTGQCEHVLTGHVAAVRCVQYDGRRVVSGGYDYMVKVWDPETEVCLHTLQGHTNRVYSLQFDGAFVVSGSLDTSIRVWDA--ETGGCVHTLTGHQSLTSGMELRDNILVSGNADSTVRVWDIRTGLCLHTLQG 464          

Query:  680 NFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYE--VRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCKLWRYDEKNSFATMR-HKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWS--TVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIR-VIRGNSR-SDPILNLVVKDDTLIINTV--------SNILVLNFE 2074
             F  DFIS LP  ++  ++ FL  + L   ++ C  W+ +  +  + RE      I + A   + +     +   +P    + R   +     +  +   + +     H      +  D        N+ KV+S   A      + L      ++C   +V  ++ S S +R  LR      G  V                       +++ GH  +++ +     H  +                   ++SGS DT++R W+  TG+C  +  GH   +  +        SG YD   K+W  + +    T++ H + + ++       VSG     I+VW+ + G  + +L+GH    S + L    ++S + D+ V +W   T     T  G   H  +V  ++F     ++   DG +++W++  G  +R V+   SR S  ++  +   DT ++           + +L+++F+
Sbjct:  119 QFQRDFISLLPKELALYVLTFLPPRDLLRAAQTCRYWRILAEDNLLWREKCREEGISESASYRRRESVRPSAAAVSPWKSAYIRQHRIETNWRKGDTGEPMVLKGHDDHVITCLQFSGDLIVSGSDDNTLKVWS---AVTGKCLQTLTGHTGGVWCSQMAVATVI-SGSTDR-TLRVWDAESGECV-----------------------HTLYGHTSTVRCMHL---HGNR-------------------VVSGSRDTTLRVWNVTTGQCEHVLTGHVAAVRCVQYDGRRVVSGGYDYMVKVWDPETEVCLHTLQGHTNRVYSLQFDGAFVVSGSLDTSIRVWDAETGGCVHTLTGHQSLTSGMELRDNILVSGNADSTVRVWDIRTGLCLHTLQGPNKHQSAVTCLQFCRGLVLSSSDDGTVKLWDLRTGAWLRDVVALQSRGSGGVVWRIKASDTRLVCAAGSRNGTEETKLLIMDFD 548          

Query: 1613 MRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPSCSLSLPENKKSQIKRNNFRHISQRCERSRLAGNIDPRIFITPNTEGLEMNSKCLLSNQEFSYARSFENGNPMTRSTAWHVSPSFYKSQNHSMKPPLHKSKDLVDSVEDNKFTTESRINLVKXXXXXXXXXXXXYGFERQDHLLIDSDLQEIKQTLRNHIRSPPQIAAEAMPEFIKTMVSQLKTSNLTGRSVSAFSLNRFVRPSSGPSKIDSKSKIGFEEMKAVVSPLTQQTVKDFSETINPKNHSKNQINQPVNEENIWKPVFSSNFKTSNNSISQSKFGSFFIPPDYRQRLAEKKFEFDQKHHSNVNHQPINGGVETSKRSKCKLVVNDLNLQTFENAQQCFEQIEKRQVRYKMEQKSKIDKEYHLKWIKRATESPNIKFGKDALMKRPRSAKI 3313
            MRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPS S+SLPENKKSQIKRNNFRHISQRCERSRLAGNIDPRIFITPNTEGLEMNSKCLLSNQEFSYARSFENGNPMTRSTAWHVSPSFYKSQNHSMKPPLHKSKDLVDSVEDNKFTTESRINLVKSTRVSQSTRRVSYGFERQDHLLIDSDLQEIKQTLRNHIRSPPQIAAEAMPEFIKTMVSQLKTSNLTGRSVSAFSLNRFVRPSSGPSKIDSKSKIGFEEMK VVSPLTQQTVKDFSETINPKNHSKNQINQPVNEENIWKPVFSSNFKTSNNSISQSKFGSFFIPPDYRQRLAEKKFEFDQKHHSNVNHQPINGGVETSKRSKCKLVVNDLNLQTFENAQQCFEQIEKRQVRYKMEQKSKIDKEYHLKWIKRATESPNIKFGKDALMKRPRSAKI
Sbjct:    1 MRHKHPITAVAISEKLCVSGDSLGLIKVWNIQNGVYIKSLSGHFKEISAIRLDSWHILSASLDNFVMLWSTVGEFDTCIGNFHHPKSVLSMEFQFLRAVTGCADGKIRIWNILNGHCIRVIRGNSRSDPILNLVVKDDTLIINTVSNILVLNFEPIDWMYENGKDYTLNQPSFSVSLPENKKSQIKRNNFRHISQRCERSRLAGNIDPRIFITPNTEGLEMNSKCLLSNQEFSYARSFENGNPMTRSTAWHVSPSFYKSQNHSMKPPLHKSKDLVDSVEDNKFTTESRINLVKSTRVSQSTRRVSYGFERQDHLLIDSDLQEIKQTLRNHIRSPPQIAAEAMPEFIKTMVSQLKTSNLTGRSVSAFSLNRFVRPSSGPSKIDSKSKIGFEEMKTVVSPLTQQTVKDFSETINPKNHSKNQINQPVNEENIWKPVFSSNFKTSNNSISQSKFGSFFIPPDYRQRLAEKKFEFDQKHHSNVNHQPINGGVETSKRSKCKLVVNDLNLQTFENAQQCFEQIEKRQVRYKMEQKSKIDKEYHLKWIKRATESPNIKFGKDALMKRPRSAKI 567          

Query:   32 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCK 1576
            MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRK+FSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFG RTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIY+GHSGTISDID GEEIFASGSYDGTCK
Sbjct:    1 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKIFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGNRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYLGHSGTISDIDTGEEIFASGSYDGTCK 515          

Query:   32 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCK 1576
            MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQ       SVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRK+FSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFG RTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIY+GHSGTISDID GEEIFASGSYDGTCK
Sbjct:    1 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQ-------SVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKIFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGNRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYLGHSGTISDIDTGEEIFASGSYDGTCK 508          

Query:   32 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCK 1576
            MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHI                  +CEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRK+FSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFG RTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIY+GHSGTISDID GEEIFASGSYDGTCK
Sbjct:    1 MDEHILKCLDSIEISKNNIFNGTIFICKENPNPNPCQNCITCKLVILKDFSVSLLNHMPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHI------------------ICEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKIFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGNRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYLGHSGTISDIDTGEEIFASGSYDGTCK 497          

Query:  203 MPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKVFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGKRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYIGHSGTISDIDAGEEIFASGSYDGTCK 1576
            MPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRK+FSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFG RTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIY+GHSGTISDID GEEIFASGSYDGTCK
Sbjct:    1 MPDNDVINFITKCSKTESYTELTGVLQHILYPLKAKDRLYSLSRNVPSLNTDLSDFSIKNFTIDKAQLEYVTHRISNWISLQPDTFRIQFIISLLAHLKLAVLSEIYNAISTNKDSSTDSSYTSNEIINTDSDPVTLLQRVCKISANHIFEDKHSEKNNNFAVDFISNLPVHISKRIINFLDEKSLNVCSKVCEIWQQIVYEVRREDIVNAKIKKQAMMLQSQKDESKSVFTAPADPRFARDTNVRVPQLEPHSHRIIYINNSPPHTTNKDTYQIDNFNELELINSRKIFSMDVAYQNILTKKLIIEERNIFCGSYSVMIILESQSRNRDPLRTISYNGGLLVAVSGTNKIIQFLDKRGIQTEIMKNSIRGHAGSIKVVKFLNKHNKKFFGNRTYDSYNNICHEDVEILSGSYDTSIRRWDTFTGKCLKIYLGHSGTISDIDTGEEIFASGSYDGTCK 458