Synaptic vesicle 2-related protein

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYL-----AGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +FVGM   S ++G +SD+YGRK  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  +L V ++P  GWR+ LI+S  P+L+  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C       +   K    +  S  C  ++      +L +   E    L+ + +I  + RK  + + F+I +   LL+  C+  + + +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL     +G  L  A+ +        LP ETK R L +S   +  +
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVC------GISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASC------FLPIETKGRGLQESSHREWGQ 527          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLI--ISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNA--DRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSN-VGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQ 1485
            +++    IGFG FH+ + LI G      A+E +L++ + P++ C+W++   + + +T  +F G  + S++FG L+D+YGR  +++ S     YFS+ ++ +P+  W +  R  +G  + G S  +    TE +    RG  +   Q+FW  GS  I  L  VI+P  GWR WLI   SI  ++++V F F + ES R+ +       A+  + ++AKMN +       ++    K+    D+    Y+ +T     I      ++YG + +S+ +      C     + +  +   +  + S C C     +  +T++IS  GE+    + I+ I ++ R++ L I     AL +LL+N C S +  +G L M  R           +Y +EV+PT +R+  +G   S  R GAM + FI  +LM   S L    LF ++     +  F LP ETK RAL Q
Sbjct:   34 VEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLIIK-TEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWR-WLIRVASIPGIILIVAFKF-IPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFML-RALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLM-SASILGALCLFSSVCVVCAISAFTLPIETKGRALQQ 490          

Query:  505 TEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLI--ISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNA--DRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSN-VGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQ 1485
            TE +    RG  +   Q+FW  GS  I  L  VI+P  GWR WLI   SI  ++++V F F + ES R+ +       A+  + ++AKMN +       ++    K+    D+    Y+ +T     I      ++YG + +S+ +      C     + +  +   +  + S C C     +  +T++IS  GE+    + I+ I ++ R++ L I     AL +LL+N C S +  +G L M  R           +Y +EV+PT +R+  +G   S  R GAM + FI  +LM   S L    LF ++     +  F LP ETK RAL Q
Sbjct:   10 TEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWR-WLIRVASIPGIILIVAFKF-IPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFML-RALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLM-SASILGALCLFSSVCVVCAISAFTLPIETKGRALQQ 338          

Query:  505 TEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLI--ISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNA--DRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSN-VGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQ 1485
            TE +    RG  +   Q+FW  GS  I  L  VI+P  GWR WLI   SI  ++++V F F + ES R+ +       A+  + ++AKMN +       ++    K+    D+    Y+ +T     I      ++YG + +S+ +      C     + +  +   +  + S C C     +  +T++IS  GE+    + I+ I ++ R++ L I     AL +LL+N C S +  +G L M  R           +Y +EV+PT +R+  +G   S  R GAM + FI  +LM   S L    LF ++     +  F LP ETK RAL Q
Sbjct:   10 TEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWR-WLIRVASIPGIILIVAFKF-IPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFML-RALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLM-SASILGALCLFSSVCVVCAISAFTLPIETKGRALQQ 338          

Query:  556 LFWSMGSYYISLLTVVIVPLYGWRFWLI--ISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNA--DRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSN-VGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQ 1485
            +FW  GS  I  L  VI+P  GWR WLI   SI  ++++V F F + ES R+ +       A+  + ++AKMN +       ++    K+    D+    Y+ +T     I      ++YG + +S+ +      C     + +  +   +  + S C C     +  +T++IS  GE+    + I+ I ++ R++ L I     AL +LL+N C S +  +G L M  R           +Y +EV+PT +R+  +G   S  R GAM + FI  +LM   S L    LF ++     +  F LP ETK RAL Q
Sbjct:   59 VFWLAGSLLIIGLASVIIPTIGWR-WLIRVASIPGIILIVAFKF-IPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFML-RALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLM-SASILGALCLFSSVCVVCAISAFTLPIETKGRALQQ 370          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNAD-----RVTKIKYTEYKQSSVKDMFHPNYISSTFI--CMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQS 1488
            +DE    +GFG F + + ++ G      A+E +LLS + P L C+W IS ++ + +T  +F GM L S  +G + D++GR+  +  S        + S +SP  + ++  R   GF IGG    V  Y  E +   QR   V+ ++ FW++G+ + +LL   ++  +GWR  + +S  P+ I  + SF L ES R+ M       A++ +   A+MN         V+  K     +  + ++  P+   +T +  C++              +    +H    C        H   ++N  T    C P+T +    +L +   E    +I +++I++  RK  + + + + A+   L+ FCL    V +L+   R       +   +Y  EV+PT +R+  +G  ++ AR GA+ + FI  +   K   L    ++      G +    LP ETK R +  S
Sbjct:   69 VDEAVEALGFGRFQLKLSILTGMAWMADAMEMMLLSLISPALACEWGISSVQQALVTTCVFSGMMLSSTFWGKICDRFGRRKGLTFSTLVACIMGVISGMSPHFYVLLFFRGLTGFGIGGVPQSVTLY-AEFLPTAQRAKCVVLIESFWAIGAVFEALLAYFVMESFGWRALMFLSSLPLGIFAVASFWLPESARFDMASGHPERALETLQAAARMNRVQLPTGRLVSSTKAGSESRGDIANLLSPDLRKTTILLWCIWAITAFSYYGMVLFTTVLFQSH--DEC--------HGGLFSN-GTQMEVCQPLTRSDYFDLLSTTLAEFPGLIITVLIIEWFGRKKTMALEYAVFAIFTFLLYFCLDRFTVTVLIFVARAFISGAFQCAYVYTPEVYPTTLRAVGLGTCSAMARIGAIVTPFIAQVASEKSLSLP-IGIYGTAAILGLIASLSLPIETKGRQMMDS 519          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNAD-----RVTKIKYTEYKQSSVKDMFHPNYISSTFI--CMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQS 1488
            +DE    +GFG F + + ++ G      A+E +LLS + P L C+W IS ++ + +T  +F GM L S  +G + D++GR+  +  S        + S +SP  + ++  R   GF IGG    V  Y  E +   QR   V+ ++ FW++G+ + +LL   ++  +GWR  + +S  P+ I  + SF L ES R+ M       A++ +   A+MN         V+  K     +  + ++  P+   +T +  C++              +    +H    C        H   ++N  T    C P+T +    +L +   E    +I +++I++  RK  + + + + A+   L+ FCL    V +L+   R       +   +Y  EV+PT +R+  +G  ++ AR GA+ + FI  +   K   L    ++      G +    LP ETK R +  S
Sbjct:   69 VDEAVEALGFGRFQLKLSILTGMAWMADAMEMMLLSLISPALACEWGISSVQQALVTTCVFSGMMLSSTFWGKICDRFGRRKGLTFSTLVACIMGVISGMSPHFYVLLFFRGLTGFGIGGVPQSVTLY-AEFLPTAQRAKCVVLIESFWAIGAVFEALLAYFVMESFGWRALMFLSSLPLGIFAVASFWLPESARFDMASGHPERALETLQAAARMNRVQLPTGRLVSSTKAGSESRGDIANLLSPDLRKTTILLWCIWAITAFSYYGMVLFTTVLFQSH--DEC--------HGGLFSN-GTQMEVCQPLTRSDYFDLLSTTLAEFPGLIITVLIIEWFGRKKTMALEYAVFAIFTFLLYFCLDRFTVTVLIFVARAFISGAFQCAYVYTPEVYPTTLRAVGLGTCSAMARIGAIVTPFIAQVASEKSLSLP-IGIYGTAAILGLIASLSLPIETKGRQMMDS 519          

Query:  199 YAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSY---YISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLL-ESPRYLMIKNRVNDAVKVVNKIAKMN---------NADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSA----GTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNM----LMIKYSYLAG-----TLLFCAI--NTAGFLLIFLLPFETK 1467
            Y  E+V + F     ICD    +   + IT+  F G+ +G+ +FG +SD +GR+  ++ S  G   F++ S+ SP++F+ ++ R   G F GG + +   YM E   I +     I   + WS       YI+ L         WR  L + IS   ++   +  LL ESPR+L+ K ++ +A +++ KI K +         + D V KI+  +   SS K   +      TFI ++  +        F+      N I +  L +M+  L  S Y N    S+      W  +  +++SI    + +  G  LI ++     L  L ++   VY+         N G ++  G   A      +     L ++E++PT +R+ ++   ++ +R G MFS  +  +      I Y+ L G      +LFC     T G  L   LP E K
Sbjct:  106 YQFESVQVEF---NYICDDAKKV--KNTITIQTF-GVLVGAAIFGQVSDNFGRRKALIISCIGNAIFNLISSYSPSLFYFMLWRTVSGIFAGGLTVVQMVYMVE--NIPRHHRMWIQNSITWSPNLIIFPYIAYLA------QNWRT-LSVVISATSVLSFLALMLLEESPRWLVQKGKLEEARRLLIKIRKTDGLYTSDFEKDLDEVLKIEAEKQVISSKKSKKY------TFIHLFCTWKMIAQTMTFIVGIICTNFIVYALLYNMEK-LSGSLYWN----SAIIGAARW--VVNIVVSIADYQLPWF-GRRLINHISMIFTLASLAIVAGYVYI--------GNGGYVVAIGTTVALAMCSQLFIAKYLMVNELYPTAVRNLAVSAVSTMSRVGGMFSPQLFYLSDIAEWIPYAVLVGFQLVDLVLFCITIPETKGVHLENHLPPEHK 519          

Query:  199 YAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSY---YISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLL-ESPRYLMIKNRVNDAVKVVNKIAKMN---------NADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSA----GTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNM----LMIKYSYLAG-----TLLFCAI--NTAGFLLIFLLPFETK 1467
            Y  E+V + F     ICD    +   + IT+  F G+ +G+ +FG +SD +GR+  ++ S  G   F++ S+ SP++F+ ++ R   G F GG + +   YM E   I +     I   + WS       YI+ L         WR  L + IS   ++   +  LL ESPR+L+ K ++ +A +++ KI K +         + D V KI+  +   SS K   +      TFI ++  +        F+      N I +  L +M+  L  S Y N    S+      W  +  +++SI    + +  G  LI ++     L  L ++   VY+         N G ++  G   A      +     L ++E++PT +R+ ++   ++ +R G MFS  +  +      I Y+ L G      +LFC     T G  L   LP E K
Sbjct:  106 YQFESVQVEF---NYICDDAKKV--KNTITIQTF-GVLVGAAIFGQVSDNFGRRKALIISCIGNAIFNLISSYSPSLFYFMLWRTVSGIFAGGLTVVQMVYMVE--NIPRHHRMWIQNSITWSPNLIIFPYIAYLA------QNWRT-LSVVISATSVLSFLALMLLEESPRWLVQKGKLEEARRLLIKIRKTDGLYTSDFEKDLDEVLKIEAEKQVISSKKSKKY------TFIHLFCTWKMIAQTMTFIVGIICTNFIVYALLYNMEK-LSGSLYWN----SAIIGAARW--VVNIVVSIADYQLPWF-GRRLINHISMIFTLASLAIVAGYVYI--------GNGGYVVAIGTTVALAMCSQLFIAKYLMVNELYPTAVRNLAVSAVSTMSRVGGMFSPQLFYLSDIAEWIPYAVLVGFQLVDLVLFCITIPETKGVHLENHLPPEHK 519          

Query:  241 LIC-DWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGW-RFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQ 813
            L+C D K+  L  S I M   +G+ LG +VFG + D+YGRK  ++   C  F F I SALS       + R  + FF GG ST+   YM E   I +R    I   + +S     + LL ++      W R  L+IS   +  +++ +F L ESPR+LM K +++ A KV   I K +       +  TE + 
Sbjct:   89 LLCEDAKLEKLGTS-IQM---LGVMLGCVVFGQIGDQYGRKTPMMFCLCMCFIFGIMSALSADFKKFTIFRTILCFFNGGQSTISVVYMIE--NIPKRTRGYISTLISYSPN---VILLGILAFFFQQWDRLALVISFLTVPAIIMLAF-LHESPRWLMQKGQISHAKKVFLAIEKFDGVPAAKSLNETELEN 271          

Query:   76 IDFSMSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQS---SVKDMFHPNYISSTFICMYI------CXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNM 1368
            I+   +YT   AI         GFG FHV + L+ G      ++E  +LS LGP L C+W ++  + + +T  +F+GM L S  +  LS++YGRK  +      +  +SI S+++P+  W++  R  +GF IG     V  Y  E +    +G  V+ +  FW++G+ +  +L +V+ P YGWR  L +S +P+LI  + S  L ES RY       + A+KV+ +IA  N    +      + + S   S + +  P+   +T +  ++      C+   +     +  +      P+ C+  M         T+   D      + W T+         E    L+ I ++K   +K  + + +L   L  L++    S  +  + +   RG+   I +   +Y  E++P  +RS  +   +  AR GAM + F+  +
Sbjct:   34 INPDDTYTVQQAI------NAFGFGWFHVKLSLLVGLCWMSDSMEMAILSILGPSLFCEWNVTKFQQASVTTVVFLGMMLSSSFWTQLSNRYGRKSALTLFGVLLVLYSILSSVAPSYAWLLTLRGLVGFAIGCVPQSVTLY-AEFLPTKHKGKCVVLMDCFWALGACFEVVLALVVYPYYGWRGLLALSATPLLIFTILSPWLSESARYYSYNGHNDKAIKVLEQIAHNNKRHMLMGRLMADDEPSCAESFRSLLSPSLYRTTILLWFLWLASAFCYYGLVLVTTELLVARNKESHPNECVTFM---------TSDFMD------LLWITLS--------EFPGILLTIKVVKLFGKKKTIVLQYLALVLCTLVLMSVESRFSTSVTLFIARGTISGIFQAIYVYTPEIYPAALRSVGVSGCSVLARLGAMLTPFVAQV 443          

Query:   76 IDFSMSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQS---SVKDMFHPNYISSTFICMYI------CXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNM 1368
            I+   +YT   AI         GFG FHV + L+ G      ++E  +LS LGP L C+W ++  + + +T  +F+GM L S  +  LS++YGRK  +      +  +SI S+++P+  W++  R  +GF IG     V  Y  E +    +G  V+ +  FW++G+ +  +L +V+ P YGWR  L +S +P+LI  + S  L ES RY       + A+KV+ +IA  N    +      + + S   S + +  P+   +T +  ++      C+   +     +  +      P+ C+  M         T+   D      + W T+         E    L+ I ++K   +K  + + +L   L  L++    S  +  + +   RG+   I +   +Y  E++P  +RS  +   +  AR GAM + F+  +
Sbjct:   34 INPDDTYTVQQAI------NAFGFGWFHVKLSLLVGLCWMSDSMEMAILSILGPSLFCEWNVTKFQQASVTTVVFLGMMLSSSFWTQLSNRYGRKSALTLFGVLLVLYSILSSVAPSYAWLLTLRGLVGFAIGCVPQSVTLY-AEFLPTKHKGKCVVLMDCFWALGACFEVVLALVVYPYYGWRGLLALSATPLLIFTILSPWLSESARYYSYNGHNDKAIKVLEQIAHNNKRHMLMGRLMADDEPSCAESFRSLLSPSLYRTTILLWFLWLASAFCYYGLVLVTTELLVARNKESHPNECVTFM---------TSDFMD------LLWITLS--------EFPGILLTIKVVKLFGKKKTIVLQYLALVLCTLVLMSVESRFSTSVTLFIARGTISGIFQAIYVYTPEIYPAALRSVGVSGCSVLARLGAMLTPFVAQV 443          

Query:  106 PAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVP------------LYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNAD-RVTKIKYTEYKQSS-------------VKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSK-YTNHSTD--------SSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNM 1368
            PA+ +D     IG+GL  V + ++  F+  +   E++   +L  +  C++  S  E + +  +L  GM    +  G L+D+YGRK V+  +  G   FS+ SAL P ++ + + R  +G F+   +++   ++ E   I  R  +V        +   Y  L+ + I+P            L  WRF ++  + P  + ++    + E+P +LM  NR + A+  +  I +MN        I  +E K S+              K +F   ++   FIC+++ F    +  G      V+ ++ +     +  +++ +  + NH  D        S  C     N I  V    T  +  +++  VL+ ++ RK  + +  LI+ ++ + +N    P+ V I  +      G ++ +    + +  P N+R  ++ +  S AR G +  S ++ +
Sbjct:    2 PAMDVDTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGFLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVIRNMDNSGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFT-YIGCFILASVLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLPGVLIPLATSVLVDCLPVNLRGKALCMVRSLARFGGVLGSTMIGL 456          

Query:  142 GFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPL-----------YGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEY 807
            G+G FH  +L I G V     ++ + +SF+ P   CD  ++     ++   +F+GM +G+  +G+++D +GRK V++  +    +  + S+ S T  + ++ R   G  +GG   ++++Y  E     +RG+ +  +  FW+ G+ +++ L  +I+P              WR +L++   P  +V    F L ESP++L+ + + + A+ +   I   N     TK +  EY
Sbjct:  145 GYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTN-----TKRRPDEY 372          

Query:  142 GFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPL-----------YGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEY 807
            G+G FH  +L I G V     ++ + +SF+ P   CD  ++     ++   +F+GM +G+  +G+++D +GRK V++  +    +  + S+ S T  + ++ R   G  +GG   ++++Y  E     +RG+ +  +  FW+ G+ +++ L  +I+P              WR +L++   P  +V    F L ESP++L+ + + + A+ +   I   N     TK +  EY
Sbjct:  145 GYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTN-----TKRRPDEY 372          

Query:   91 SYTTNPAIP----------LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHP-NYISSTF--ICMYICXXXXXXXXXXXXXXXXXNHIPHR---CLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIK-----YSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSV 1491
            S   NP  P          ++E    IGFG FH+ + +I G      A+E +LL+ + P + C+W +   + + ++  +F G  +  ++ G ++DKYGR  VV        YFS  ++ S +  W I  RC +G  +   ++  +   TE +    R   +    +FW MGS  I +L + +VP  GWR+ +  S+ P L+++     + ES R+ +    +  A+  + +IAKMNN      +   E ++  V +  +    ISS F    + + +   ++ + +  S    + +  +   C+ D   + H  K+    T   C  P   +  +T+LIS  GE+    + I+L+  V RK  + IL L++A  ++L+N C +     IL+   R        V  +Y +EV+PT++RS  +G   SF+R G M + FI  +LM K      S  A   + CAI       +F LP ET+ RAL Q  
Sbjct:   32 SNNNNPVEPAQVKEPKCYTVEEAVESIGFGCFHILLFVIMGSANIVEAMEIMLLAVVSPEIRCEWHLEDWQVALVSTMVFFGFMVCGVLCGYIADKYGRWKVVFGGFVWASYFSFLTSFSTSYGWFIFLRCMVGCGVAA-TSQGFVLKTEFIPAKYRAYLLPLASIFWMMGSILIIVLGMTVVPTMGWRWMIRFSVIPSLVLIGLFMFIPESARFQVSAGNIQGAMSTLKRIAKMNNG----VLPEGELREPEVTERGNAVTLISSAFRRTSLLLWYSWFVASFSYYGSVLSSSELLEKNLLCVTD-PDLEHQIKHIQEETLCYCI-PFNSDDYQTLLISCLGEVALIPLNIILLNIVGRKYSMVILLLLSAFFFMLVNICTTMLGFTILLFLLRSVVSMNFNVVYIYTAEVYPTSVRSIGMGFCTSFSRIGGMIAPFIAQVLMSKSVILALSPFATACIICAIG------VFFLPIETRGRALLQDA 506          

Query:   91 SYTTNPAIP----------LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHP-NYISSTF--ICMYICXXXXXXXXXXXXXXXXXNHIPHR---CLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIK-----YSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSV 1491
            S   NP  P          ++E    IGFG FH+ + +I G      A+E +LL+ + P + C+W +   + + ++  +F G  +  ++ G ++DKYGR  VV        YFS  ++ S +  W I  RC +G  +   ++  +   TE +    R   +    +FW MGS  I +L + +VP  GWR+ +  S+ P L+++     + ES R+ +    +  A+  + +IAKMNN      +   E ++  V +  +    ISS F    + + +   ++ + +  S    + +  +   C+ D   + H  K+    T   C  P   +  +T+LIS  GE+    + I+L+  V RK  + IL L++A  ++L+N C +     IL+   R        V  +Y +EV+PT++RS  +G   SF+R G M + FI  +LM K      S  A   + CAI       +F LP ET+ RAL Q  
Sbjct:   32 SNNNNPVEPAQVKEPKCYTVEEAVESIGFGCFHILLFVIMGSANIVEAMEIMLLAVVSPEIRCEWHLEDWQVALVSTMVFFGFMVCGVLCGYIADKYGRWKVVFGGFVWASYFSFLTSFSTSYGWFIFLRCMVGCGVAA-TSQGFVLKTEFIPAKYRAYLLPLASIFWMMGSILIIVLGMTVVPTMGWRWMIRFSVIPSLVLIGLFMFIPESARFQVSAGNIQGAMSTLKRIAKMNNG----VLPEGELREPEVTERGNAVTLISSAFRRTSLLLWYSWFVASFSYYGSVLSSSELLEKNLLCVTD-PDLEHQIKHIQEETLCYCI-PFNSDDYQTLLISCLGEVALIPLNIILLNIVGRKYSMVILLLLSAFFFMLVNICTTMLGFTILLFLLRSVVSMNFNVVYIYTAEVYPTSVRSIGMGFCTSFSRIGGMIAPFIAQVLMSKSVILALSPFATACIICAIG------VFFLPIETRGRALLQDA 506          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPS-----KYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W +   E + +T  +F+GM + S ++G +SDKYGRK  +  S     ++ I SA +P   WI+  R  +GF IGG    V  Y  E + +  R T ++ +++FW++G+ +  LL ++++P  GWR+ L +S  P+ I     F L ES RY ++      A+  + +IA  NN        I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C     + + P      KY N             +  K +L +   E    L+ +  I  + R+  + + F + +L  + +  C+  +++ + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + F+  +++    YL  ++  C    A  +    LP ET  R L +S   +  +
Sbjct:   63 TDDTFMVEDAVEAIGFGTFQWKLSILTGLSWMADAMEMMILSILAPQLHCEWALPSWEVALLTSVVFIGMMISSSLWGNISDKYGRKTGLKMSVLWTLFYGILSAFAPIYGWILFLRALVGFGIGGAPQSVTLY-AEFLPMRSRATCILLIEIFWALGTVFEVLLAILVMPTLGWRWLLALSTIPLFIFAFLCFWLPESARYDVLTGNQEKALNTLKRIAAENNVPMPLGKLIVARQEDRGKIQDLFSPHFRWTTVLLWFIWFSNAFSYYGVVLLTTELFQEGGVCGGAKGSKMEPGCSLECKYLNS------------DDYKDLLWTTLSEFPGLLVTLWAIDRLGRRKTMALCFFVFSLCIVPLYSCVGRTSLTVFIFIARAFIAGGFQAAYVYTPEVYPTATRALGLGTSSGMARVGALITPFVAQVMLESSVYLTLSVYCCCCLLAA-IASCALPIETTGRGLQESSHREWGQ 525          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPS-----KYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W +   E + +T  +F+GM + S ++G +SDKYGRK  +  S     ++ I SA +P   WI+  R  +GF IGG    V  Y  E + +  R T ++ +++FW++G+ +  LL ++++P  GWR+ L +S  P+ I     F L ES RY ++      A+  + +IA  NN        I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C     + + P      KY N             +  K +L +   E    L+ +  I  + R+  + + F + +L  + +  C+  +++ + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + F+  +++    YL  ++  C    A  +    LP ET  R L +S   +  +
Sbjct:   53 TDDTFMVEDAVEAIGFGTFQWKLSILTGLSWMADAMEMMILSILAPQLHCEWALPSWEVALLTSVVFIGMMISSSLWGNISDKYGRKTGLKMSVLWTLFYGILSAFAPIYGWILFLRALVGFGIGGAPQSVTLY-AEFLPMRSRATCILLIEIFWALGTVFEVLLAILVMPTLGWRWLLALSTIPLFIFAFLCFWLPESARYDVLTGNQEKALNTLKRIAAENNVPMPLGKLIVARQEDRGKIQDLFSPHFRWTTVLLWFIWFSNAFSYYGVVLLTTELFQEGGVCGGAKGSKMEPGCSLECKYLNS------------DDYKDLLWTTLSEFPGLLVTLWAIDRLGRRKTMALCFFVFSLCIVPLYSCVGRTSLTVFIFIARAFIAGGFQAAYVYTPEVYPTATRALGLGTSSGMARVGALITPFVAQVMLESSVYLTLSVYCCCCLLAA-IASCALPIETTGRGLQESSHREWGQ 515          

Query:   91 SYTTNPAIP----------LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHP-NYISSTF--ICMYICXXXXXXXXXXXXXXXXXNHIPHR---CLQDMKTILHPSKYTNHSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIK-----YSYLAGTLLFCAINTAGFLLIFLLPFETKDRAL 1479
            S   NP  P          ++E    IGFG FH+ + +I G      A+E +LL+ + P + C+W +   + + ++  +F G  +  ++ G ++DKYGR  VV        YFS  ++ S +  W I  RC +G  +   ++  +   TE +    R   +    +FW MGS  I +L + +VP  GWR+ +  S+ P L+++     + ES R+ +    +  A+  + +IAKMNN      +   E ++  V +  +    ISS F    + + +   ++ + +  S    + +  +   C+ D   + H  K+     +  C C P   +  +T+LIS  GE+    + I+L+  V RK  + IL L++A  ++L+N C +     IL+   R        V  +Y +EV+PT++RS  +G   SF+R G M + FI  +LM K      S  A   + CAI       +F LP ET+ RAL
Sbjct:   32 SNNNNPVEPAQAKEPKCYTVEEAVESIGFGRFHILLFVIMGSANIVEAMEIMLLAVVSPEIRCEWHLEDWQVALVSTMVFFGFMVCGVLCGYIADKYGRWKVVFGGFVWASYFSFLTSFSTSYGWFIFLRCMVGCGVAA-TSQGFVLKTEFIPAKYRAYLLPLASIFWMMGSILIIVLGMTVVPTMGWRWMIRFSVIPSLVLIGLFMFIPESARFQVSAGNIQGAMSTLKRIAKMNNG----VLPEGELREPEVTERGNAVTLISSAFRRTSLLLWYSWFVASFSYYGSVLSSSELLEKNLLCVTD-PDLEHQIKHIQE--EMLCYCIPFNSDDYQTLLISCLGEVALIPLNIILLNIVGRKYSMVILLLLSAFFFMLVNICTTMLGFTILLFLLRSVVSMNFNVVYIYTAEVYPTSVRSIGMGFCTSFSRIGGMIAPFIAQVLMSKSVILALSPFATACIICAIG------VFFLPIETRGRAL 502          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGR+  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL + ++P  GWR+ LI+S  P+ +  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P +  +T +  +I F +  S+YG V  ++ +      C   +K     SK       S  C  +T      +L +   E    LI + +I  V RK  + I F++ +L  LL+  C+  + + + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   L++        L    LP ETK R L +S   +  +
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSMLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMASSSLWGNVSDQYGRRTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKSRAKCILLIEVFWAIGTVFEVLLAIFVMPTLGWRWLLILSALPLFLFAILCFWLPESARYEVLSGNQEKALATLKRIATENGAPMPLGKLIVSRQEDRGKIRDLFSPQFRRTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSSKLK-----SKTMCRPKCSLACEYLTVEDYTDLLWTTLSEFPGVLITLWIIDRVGRKKTMAICFIVFSLCALLLFLCVGRNVLTVFLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSIYLT-VLVYSGCCVLAALASCFLPIETKGRGLQESSHREWGQ 528          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGR+  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL + ++P  GWR+ LI+S  P+ +  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P +  +T +  +I                  N   +  L  + T L  +        S  C  +T      +L +   E    LI + +I  V RK  + I F++ +L  LL+  C+  + + + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   L++        L    LP ETK R L +S   +  +
Sbjct:  110 TDDTFMVEDAVEAIGFGKFQWKLSMLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMASSSLWGNVSDQYGRRTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKSRAKCILLIEVFWAIGTVFEVLLAIFVMPTLGWRWLLILSALPLFLFAILCFWLPESARYEVLSGNQEKALATLKRIATENGAPMPLGKLIVSRQEDRGKIRDLFSPQFRRTTLLLWFI---------------WFSNAFSYYGLVLLTTELFQAGDAVKPKCSLACEYLTVEDYTDLLWTTLSEFPGVLITLWIIDRVGRKKTMAICFIVFSLCALLLFLCVGRNVLTVFLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSIYLT-VLVYSGCCVLAALASCFLPIETKGRGLQESSHREWGQ 564          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGR+  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL + ++P  GWR+ LI+S  P+ +  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P +  +T +  +I F +  S+YG V  ++ +      C          SK       S  C  +T      +L +   E    LI + +I  V RK  + I F++ +L  LL+  C+  + + + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   L++        L    LP ETK R L +S   +  +
Sbjct:   58 TDDTFMVEDAVEAIGFGKFQWKLSMLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMASSSLWGNVSDQYGRRTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKSRAKCILLIEVFWAIGTVFEVLLAIFVMPTLGWRWLLILSALPLFLFAILCFWLPESARYEVLSGNQEKALATLKRIATENGAPMPLGKLIVSRQEDRGKIRDLFSPQFRRTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVC---------SSKKAVKPKCSLACEYLTVEDYTDLLWTTLSEFPGVLITLWIIDRVGRKKTMAICFIVFSLCALLLFLCVGRNVLTVFLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSIYLT-VLVYSGCCVLAALASCFLPIETKGRGLQESSHREWGQ 518          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRC-LQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGR+  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL + ++P  GWR+ LI+S  P+ +  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P +  +T +  +I F +  S+YG V  ++ +      C + + +  + P         S  C  +T      +L +   E    LI + +I  V RK  + I F++ +L  LL+  C+  + + + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   L++        L    LP ETK R L +S   +  +
Sbjct:   63 TDDTFMVEDAVEAIGFGKFQWKLSMLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMASSSLWGNVSDQYGRRTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKSRAKCILLIEVFWAIGTVFEVLLAIFVMPTLGWRWLLILSALPLFLFAILCFWLPESARYEVLSGNQEKALATLKRIATENGAPMPLGKLIVSRQEDRGKIRDLFSPQFRRTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISNQRKAVKPKC-------SLACEYLTVEDYTDLLWTTLSEFPGVLITLWIIDRVGRKKTMAICFIVFSLCALLLFLCVGRNVLTVFLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSIYLT-VLVYSGCCVLAALASCFLPIETKGRGLQESSHREWGQ 526          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLI------VVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRC-LQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGR+  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL + ++P  GWR+ LI+S  P+ +      V LF  +L     + M +N           I  +   DR             ++D+F P +  +T +  +I F +  S+YG V  ++ +      C + + +  + P         S  C  +T      +L +   E    LI + +I  V RK  + I F++ +L  LL+  C+  + + + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   L++        L    LP ETK R L +S   +  +
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSMLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMASSSLWGNVSDQYGRRTGLKISVFWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKSRAKCILLIEVFWAIGTVFEVLLAIFVMPTLGWRWLLILSALPLFLFAILCFVSLFYLKLYFYFSFTMKRN-----------ILFVLKEDR-----------GKIRDLFSPQFRRTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISNQRKAVKPKC-------SLACEYLTVEDYTDLLWTTLSEFPGVLITLWIIDRVGRKKTMAICFIVFSLCALLLFLCVGRNVLTVFLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSIYLT-VLVYSGCCVLAALASCFLPIETKGRGLQESSHREWGQ 509          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWL--IISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNA--DRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTD--SSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSN-VGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQ 1485
            +++    IGFG FH+ + LI G      A+E +L++ + P++ C+W++   + +F+T  +F G  + S++FG L+D+YGR  +++ S     YFS+ ++ SP+  W +  R  +G  + G +  +    TE +    RG  +   Q+FW  GS  I  +  V++P  GWR WL  I SI  +++++ F F + ES R+ +       A+  +  IAKMN +       ++    K+    D+    Y+ +T     I      ++YG + +S+ +      C    ++     + T  S +  S C C     +  +T++IS  GE+    + I+ I ++ R++ L I     AL +LL+N C S +  +G L M  R           +Y +EV+PT +R+  +G   S  R GAM + FI  +LM   S+L    LF ++     +  F LP ETK RAL Q
Sbjct:   34 VEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLIIK-TEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIGWR-WLIRIASIPGIILIMAFKF-IPESARFNVSTGNTQAALNTLESIAKMNRSVMPEGQLVEPILEKRGRFADLLDSKYLRTTLQIWIIWLGISFAYYGVILASAELLERDLVCGSKSESEPEVVETTGDSGEGLSPCYCHIFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFML-RALVAANFNTIYIYTAEVYPTPMRAIGMGTSGSLCRIGAMVAPFISQVLM-SASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQ 492          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQS 1488
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGRK  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL V ++P  GWR+ L++S +P+L+  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C       +   K    +  S  C  ++      +L +   E    L+ + +I  + RK  + + F+I +L  LL+  C+  + + +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   +       AG    F LP ETK RAL +S
Sbjct:   64 TDDTFMVEDAVEAIGFGRFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVLLAVFVMPSLGWRWLLLLSAAPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVC------SISSRKKAVEAKCSLACEYLSKEDYMDLLWTTLSEFPGVLVTLWVIDRLGRKKTMALCFIIFSLCSLLLFICIGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAGVASCF-LPIETKGRALQES 520          

Query:   88 MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYG-------------WRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIK 795
            M      A   + I  + G G F  T+  + G       VE  ++SF  P    D  +S  +   + + +++GM  G+ + G L+DK GRK V+  S      F+  S+        +  R   G  IGG   +V+ Y +E ++ ++RG  +  + +FW  G  Y S +   I+P YG             WR ++I+   P  + ++    + ESPR+L+   + ++A  ++ ++   N   + T  K
Sbjct:   85 MEDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEK 333          

Query:   88 MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYG-------------WRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIK 795
            M      A   + I  + G G F  T+  + G       VE  ++SF  P    D  +S  +   + + +++GM  G+ + G L+DK GRK V+  S      F+  S+        +  R   G  IGG   +V+ Y +E ++ ++RG  +  + +FW  G  Y S +   I+P YG             WR ++I+   P  + ++    + ESPR+L+   + ++A  ++ ++   N   + T  K
Sbjct:   85 MEDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEK 333          

Query:   88 MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYG-------------WRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIK 795
            M      A   + I  + G G F  T+  + G       VE  ++SF  P    D  +S  +   + + +++GM  G+ + G L+DK GRK V+  S      F+  S+        +  R   G  IGG   +V+ Y +E ++ ++RG  +  + +FW  G  Y S +   I+P YG             WR ++I+   P  + ++    + ESPR+L+   + ++A  ++ ++   N   + T  K
Sbjct:   85 MEDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEK 333          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRC-LQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +F+GM   S ++G +SD+YGR+  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  LL + ++P  GWR+ LI+S  P+++  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P +  +T +  +I F +  S+YG V  ++ +      C + + +  + P         S  C  +T      +L +   E    L+ + +I  V RK  + I F+I +   LL+  C+  + + + +   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL   L++        +    LP ETK R L +S   +  +
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSMLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFIGMMASSSLWGNVSDQYGRRTGLKISVIWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKSRAKCILLIEIFWALGTVFEVLLAIFVMPTLGWRWLLILSALPLMLFAILCFWLPESARYEVLSGNQEKALATLKRIATENGAPMPLGKLIVSRQEDRGKIRDLFSPQFRCTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCSISNQRKAVKPKC-------SLACEYLTVEDYTDLLWTTLSEFPGLLVTLWIIDRVGRKKTMAICFIIFSFSALLLFLCVGRNVLTVFLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSIYLT-VLVYSGCCVLAAVASCFLPIETKGRGLQESSHREWGQ 527          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYL-----AGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +FVGM   S ++G +SD+YGRK  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  +L V ++P  GWR+ LI+S  P+L+  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C       +   K    +  S  C  ++      +L +   E    L+ + +I  + RK  + + F++ +   LL+  C+  + + +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL     +G  L  A+ +        LP ETK R L +S   +  +
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVC------SISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVVFSFCSLLLFICVGRNMLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASC------FLPIETKGRGLQESSHREWGQ 527          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYL-----AGTLLFCAINTAGFLLIFLLPFETKDRALPQS 1488
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +FVGM   S ++G +SD+YGRK  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  +L V ++P  GWR+ LI+S  P+L+  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C       +   K    +  S  C  ++      +L +   E    L+ + +I  + RK  + + F+I +   LL+  C+  + + +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL     +G  L  A+ +        LP ETK R L +S
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVC------GISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASC------FLPIETKGRGLQES 520          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYL-----AGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   + + +T  +FVGM   S ++G +SD+YGRK  +  S     Y+ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R   ++ +++FW++G+ +  +L V ++P  GWR+ LI+S  P+L+  +  F L ES RY ++      A+  + +IA  N A       I   +  +  ++D+F P++  +T +  +I F +  S+YG V  ++ +      C       +   K    +  S  C  ++      +L +   E    L+ + +I  + RK  + + F+I +   LL+  C+  + + +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + FI  +++    YL     +G  L  A+ +        LP ETK R L +S   +  +
Sbjct:   64 TDDTFMVEDAVEAIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVTLY-AEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIISRQEDRGKMRDLFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVC------GISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASC------FLPIETKGRGLQESSHREWGQ 527          

Query:   91 SYTTNPAIP----------LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHP-NYISSTF--ICMYICXXXXXXXXXXXXXXXXXNHIPHR---CLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIK-----YSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSV 1491
            S   NP  P          ++E    IGFG FH+ + +I G      A+E +LL+ + P + C+W +   + + ++  +F G  +  ++ G ++DKYGR  VV        YFS  ++ S +  W I  RC +G  +   ++  +   TE +    R   +    +FW MGS  I +L + +VP  GWR+ +  S+ P L+++     + ES R+ +    +  A+  + +IAKMNN      +   E ++  V +  +    ISS F    + + +   ++ + +  S    + +  +   C+ D   + H  K+    T   C  P   +  +T+LIS  GE+    + I+L+  V RK  + IL L++A  ++L+N C +     IL+   R        V  +Y +EV+PT++RS  +G   SF+R G M + FI  +LM K      S  A   + CAI       +F LP ET+ RAL Q  
Sbjct:   32 SNNNNPVEPAQVKEPKCYTVEEAVESIGFGCFHILLFVIMGSANIVEAMEIMLLAVVSPEIRCEWHLEDWQVALVSTMVFFGFMVCGVLCGYIADKYGRWKVVFGGFVWASYFSFLTSFSTSYGWFIFLRCMVGCGVAA-TSQGFVLKTEFIPAKYRAYLLPLASIFWMMGSILIIVLGMTVVPTMGWRWMIRFSVIPSLVLIGLFMFIPESARFQVSAGNIQGAMSTLKRIAKMNNG----VLPEGELREPEVTERGNAVTLISSAFRRTSLLLWYSWFVASFSYYGSVLSSSELLEKNLLCVTD-PDLEHQIKHIQEETLCYCI-PFNSDDYQTLLISCLGEVALIPLNIILLNIVGRKYSMVILLLLSAFFFMLVNICTTMLGFTILLFLLRSVVSMNFNVVYIYTAEVYPTSVRSIGMGFCTSFSRIGGMIAPFIAQVLMSKSVILALSPFATACIICAIG------VFFLPIETRGRALLQDA 506          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNN----ADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVE 1494
            ++E   K+GFG F + +L I G +    A+E +LLS LGP L CDW+++  E + IT  +F GM LG+  +G +SDK GR  V   S C + YF +  + SP  FW++  R  +GF IGG ++  +T ++E +    R   +I   LFW +GS +  LL  +++P  GWR+ +  S  P+ + +L    L ES R+L+   R  +A  V+++IA+ N       R      +E  +  +K +FHP Y  ++FI   + F    S+YG V  S+ +      C    +++      T    D+SCC  +  +    +LIS  GE +   + ++ I  + R+  L I +L+  + + L   C+  +     +   R  +  I     +Y +EV+PT IRS  +G+ ++ AR G+M + F+  ++M   S L   +++  ++ +   L  LLP ET  RAL  S+E
Sbjct:   90 VEEAVEKLGFGRFQIKILCITGIMSAADAMEMLLLSVLGPALRCDWRLTSTEVAGITTVVFAGMLLGAPGWGAVSDKRGRWSVFALSLCLMAYFGLLCSFSPDYFWLVSLRGVVGFNIGGAASS-FTLLSEYLPQQHRAKVLILYNLFWGLGSTFEILLAYLVLPTLGWRYLVAFSSLPLFLFMLTLGHLPESARFLLASGRAEEAAAVIDQIARENRRPAMEGRPAVATVSESDRGQLKALFHPFYRRTSFILFSLWFGVAFSYYGIVLVSTEIFRFHQDCFSTAQSVTVAHNTTESVVDNSCCRGLQSDDYTAMLISSLGEFVIIPVNMLTIDALGRRATLGINYLLTGVFFGLTYLCVPKAATTAFLFLIRAHSAGIFNTIYIYTTEVYPTVIRSLGLGICSAMARLGSMTTPFVAQVIMPDVSVLLAFIIYLMVDLSCAGLCVLLPIETSGRALAHSLE 551          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNN----ADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVE 1494
            ++E   K+GFG F + +L I G +    A+E +LLS LGP L CDW+++  E + IT  +F GM LG+  +G +SDK GR  V   S C + YF +  + SP  FW++  R  +GF IGG ++  +T ++E +    R   +I   LFW +GS +  LL  +++P  GWR+ +  S  P+ + +L    L ES R+L+   R  +A  V+++IA+ N       R      +E  +  +K +FHP Y  ++FI   + F    S+YG V  S+ +      C    +++      T    D+SCC  +  +    +LIS  GE +   + ++ I  + R+  L I +L+  + + L   C+  +     +   R  +  I     +Y +EV+PT IRS  +G+ ++ AR G+M + F+  ++M   S L   +++  ++ +   L  LLP ET  RAL  S+E
Sbjct:  113 VEEAVEKLGFGRFQIKILCITGIMSAADAMEMLLLSVLGPALRCDWRLTSTEVAGITTVVFAGMLLGAPGWGAVSDKRGRWSVFALSLCLMAYFGLLCSFSPDYFWLVSLRGVVGFNIGGAASS-FTLLSEYLPQQHRAKVLILYNLFWGLGSTFEILLAYLVLPTLGWRYLVAFSSLPLFLFMLTLGHLPESARFLLASGRAEEAAAVIDQIARENRRPAMEGRPAVATVSESDRGQLKALFHPFYRRTSFILFSLWFGVAFSYYGIVLVSTEIFRFHQDCFSTAQSVTVAHNTTESVVDNSCCRGLQSDDYTAMLISSLGEFVIIPVNMLTIDALGRRATLGINYLLTGVFFGLTYLCVPKAATTAFLFLIRAHSAGIFNTIYIYTTEVYPTVIRSLGLGICSAMARLGSMTTPFVAQVIMPDVSVLLAFIIYLMVDLSCAGLCVLLPIETSGRALAHSLE 574          

Query:   97 TTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLL-ESPRYLMIKNRVNDAVKVVNKIAKMNNA-DRVTKIKYTEYKQSSVKDMFH---PNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQ-DMKTILHPSKYTNHST---DSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMF-GRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLELLIKN 1530
            T +P   ++E     G G F + V+ I G +Q   A+E +LLS LGP L C W ++  E + IT  +FVG  LG+ ++G  SDKYGRK  ++T    I YF + + LSPT  W+++ R  +GF IGG S+  Y  M E + +  R T ++  QLFW++G      L+ +I+P +GWR WLI + S  L + L    LL ES RYL   NR+ +A ++VN IAKMN   +    +  +E  +SS+ ++ H     Y+ ++ +   I F +  ++YG +  SS +     +C       I H    T   T   D+SCC  +      ++L+S  GE     + IV++  + R++ L  ++L+ A+ ++ +N C+ PS V I+ +F  R  + + + +  LY +EV+PT IRS  +GL +S +R GAM + ++  +LM + S LA    + A++    +    LP ETK RA+  SV+ +I   E+  KN
Sbjct:   11 TASPTYTVEEAIETYGLGFFQLRVVGISGILQAADAMELLLLSVLGPTLRCTWNLTPSEVALITTIVFVGYLLGAPLWGKFSDKYGRKTCLLTVLSLIAYFGLLTTLSPTYIWVLVLRGIVGFNIGGGSSS-YALMAEYLPLHHRATVLLAAQLFWAIGGSVEIGLSFLILPRFGWR-WLIFASSLPLALFLGLLLLLPESVRYLTAANRLEEAQQIVNNIAKMNKKVEMEGSLVSSESTESSLGNIMHLFAKRYLCTSLLLPIIWFGAAFTYYGSILVSSDIFRFHSQCFGVKADPIDHHGNLTAGLTPVVDTSCCVELQTEDYTSMLVSSLGEFAILPLNIVMVNVLGRRLSLAGVYLLLAIFFIAINACV-PSTVTIVFLFILRALSSSTINLVYLYTTEVYPTTIRSLGLGLFSSISRFGAMSTPYVAQVLMPEVSVLAALGTYSAMSVLCAIASGCLPIETKGRAMQHSVDSEIEISEISSKN 495          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGS------YYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKI---KYTEYKQSSVKDMF-HPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVED 1497
            +D    +IGFG F + ++ + G VQ   A+E VLLSFLG  + C W +S  + +++   +F+G  +G+ + G +SD+YGR   ++ SAC I Y+   SA SP++ WI+  R F+GF IGG   +  T   E + +  R + +I +  FW++G        ++SL +   +   GWRF L  +  P+ +++   F L  SPR+L+   R  +A+  +N+ A+ N    +T          +++S+K +F +P     T + +      G  +YG V  S+ +   PHRCLQ++  +   S  ++  + + CC  ++     T   +  GE   YLI I+ I    R+  +     + +++ + M FC+ P  + +L+ F R  A +      ++ +E +PT IR+  +G+  + +R GA+ S F+  +++  YS +A  L +  +     + + L+PF+TK R+L Q+VE+
Sbjct:   12 IDAAVEQIGFGRFQIGLVAVCGTVQAADAMEMVLLSFLGRSVQCQWHLSSQQIAWLATCVFIGTMIGAPILGAISDRYGRWNALLLSACLIAYYGALSAASPSLPWILTLRGFVGFAIGGLIPLTSTLTGEFLPVKFRASFLIVMMSFWTLGGLFEVLIAWLSLGSDGTLKPNGWRFMLAGTSVPLFLILPMFFWLPRSPRFLLASGRPEEALTQLNRAARSNKRPELTGPLSNTAARGERASLKGLFANPTMTRLTLLSIVNWIGGGFLYYGLVLLSTELPGQPHRCLQNLHQM---SAASSDKSSTECCQALSSEDYATAAFATLGEFFGYLIIILFIDTCGRRAVIASNTGVLSVLLVCMLFCMPPKLLAVLLFFARSCAASAFTAIYIFTNEAYPTTIRTLGMGVCCAASRIGALLSPFVAQVMLPDYSVMAAMLTYAGMAVVTTVCVLLMPFDTKGRSLMQTVEE 478          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKY----TEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVE 1494
            ++E   K+GFG F + +L I G +    A+E +LLS LGP L CDW+++  E + IT  +F GM LG+  +G +SDK GR  V   S C + YF +  + +P  FW++  R  +GF IGG ++  +T ++E +    R   +I   LFW +GS +  LL  +++P  GWR+ +  S  P+ + +L    L ES R+L+   R  +A  V+++IA+ N    +  +      +E  +  +K +FHP Y  ++FI   + F    S+YG V  S+ +      C    +++      T    D+SCC  +  +    +LIS  GE +   + ++ I  + R+  L I +L+  + + L   C+  +     +   R  +  I     +Y +EV+PT IRS  +G+ ++ AR G+M + F+  ++M   S L   +++  ++ +   L  LLP ET  RAL  S+E
Sbjct:  105 VEEAVEKLGFGRFQIKILCITGIMSAADAMEMLLLSVLGPALRCDWRLTSTEVAGITTVVFAGMLLGAPGWGAVSDKRGRWSVFALSLCLMAYFGLLCSFAPDYFWLVSLRGVVGFNIGGAASS-FTLLSEYLPQQHRAKVLILYNLFWGLGSTFEILLAYLVLPTLGWRYLVAFSSLPLFLFMLTLGHLPESARFLLASGRAEEAAAVIDQIARENRRPAMEGLPAVATVSESDRGQLKALFHPFYRRTSFILFSLWFGVAFSYYGIVLVSTEIFRFHQDCFSTAQSVTVAHNTTESVVDNSCCRGLQSDDYTAMLISSLGEFVIIPVNMLTIDALGRRATLGINYLLTGVFFGLTYLCVPKAATTAFLFLIRAHSAGIFNTIYIYTTEVYPTVIRSLGLGICSAMARLGSMTTPFVAQVIMPDVSVLLAFIIYLMVDLSCAGLCVLLPIETSGRALAHSLE 566          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPS-----KYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   E + +T  +F+GM + S ++G +SDKYGRK  +  S     ++ I S+ +P   WI+  R  +GF IGG    V  Y  E + +  R T ++ +++FW++G+ +  LL ++++P  GWR+ L +S  P+ I  +  F L ES RY ++      A+  + +IA  N         I   + ++  +KD+F P++  +T +  +I F +  S+YG V  ++ +      C     +   P      KY N             +  K +L +   E    L+ +  I  + R+  + + FL  +L  + +  C+  +++ +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + F+  +++    YL  ++  C    A  +    LP ET  R L +S   +  +
Sbjct:   65 TDDTFMVEDAVEAIGFGTFQWKLSILTGLSWMADAMEMMILSILAPQLHCEWRLPSWEVALLTSVVFIGMMISSSLWGNISDKYGRKTGLKMSVLWTLFYGILSSFAPIYGWILFLRALVGFGIGGAPQSVTLY-AEFLPMRSRATCILLIEVFWALGTVFEVLLAILVMPTLGWRWLLALSTIPLFIFAILCFWLPESARYDVLSGNQEKALNTLKRIATENKVPMPLGKLIVARQEERGKIKDLFLPHFRWTTILLWFIWFSNAFSYYGLVLLTTELFQEGGACGDTKGSKAEPRCNLECKYLNS------------DDYKDLLWTTLSEFPGLLVTLWAIDRLGRRKTMALCFLFFSLCIVPLYACVGRTSLTVLIFIARAFIAGGFQAAYVYTPEVYPTATRALGLGTSSGMARVGALITPFVAQVMLESSVYLTLSVYCCCCLLAA-VASCALPIETTGRGLQESSHREWGQ 527          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTIL--HPSKYTNHSTDSSC---CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++   E + +T  +F+GM + S ++G +SDKYGRK  +  S     ++ I S+ +P   WI+  R  +GF IGG    V  Y  E + +  R T ++ +++FW++G+ +  LL ++++P  GWR+ L +S  P+ I  +  F L ES RY ++      A+  + +IA  N         I   + ++  +KD+F P++  +T +  +I                  N   +  L  + T L            +  C   C  +  +  K +L +   E    L+ +  I  + R+  + + FL  +L  + +  C+  +++ +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + F+  +++    YL  ++  C    A  +    LP ET  R L +S   +  +
Sbjct:   67 TDDTFMVEDAVEAIGFGTFQWKLSILTGLSWMADAMEMMILSILAPQLHCEWRLPSWEVALLTSVVFIGMMISSSLWGNISDKYGRKTGLKMSVLWTLFYGILSSFAPIYGWILFLRALVGFGIGGAPQSVTLY-AEFLPMRSRATCILLIEVFWALGTVFEVLLAILVMPTLGWRWLLALSTIPLFIFAILCFWLPESARYDVLSGNQEKALNTLKRIATENKVPMPLGKLIVARQEERGKIKDLFLPHFRWTTILLWFI---------------WFSNAFSYYGLVLLTTELFQEGGACGGIKAEPRCNLECKYLNSDDYKDLLWTTLSEFPGLLVTLWAIDRLGRRKTMALCFLFFSLCIVPLYACVGRTSLTVLIFIARAFIAGGFQAAYVYTPEVYPTATRALGLGTSSGMARVGALITPFVAQVMLESSVYLTLSVYCCCCLLAA-VASCALPIETTGRGLQESSHREWGQ 526          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVV-LFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGT-----LLFCAINTAGFLLIFLLPFETKDRAL 1479
            ++E    IGFG FHV + +I G      A+E +LL+ + P + C+W++   + + ++  +F+G  +  ++ G ++DKYGR  VV        YFS+ ++ +P+  W I  R  +G  +   ++  +   TE +    R   +    +FW +GS  I +L + +VP  GWR+ +  SI P LI++ LF  +    PR+ +++               +N    +  I   E K      +    Y  S  +  ++   +              N +   C+ D     H  K+ N       C P      +T+LIS  GE+    + I L+  V RK+ + IL L++A+ ++L+N C +     +L+   R        V  +Y +EV+PT++RS  +G   SF+R G M + FI  +LM K   LA +        CA+ TA      LLP ET+ RAL
Sbjct:   34 VEEAVESIGFGRFHVLLFIIMGSANIVEAMEIMLLAVVSPEIRCEWRLEDWQVALVSTMVFLGFMICGVLCGYVADKYGRWKVVFGGFVWAAYFSLLTSFAPSYGWFIFLRSMVGCGVAA-TSQGFVLKTEFIPAKHRAFLLPLASIFWMVGSLLIIILGMTVVPTLGWRWMIRFSIIPSLILIGLFQVK----PRWWILE--------------YLNLFIELLLIIVLEVK------IILSRYRYSILVLKFVASFTYYGSVLSSSELLEKNLL---CVVDADA-EHGIKH-NQEEALCYCIPFNMADYQTLLISCLGEVALIPLNIGLLNVVGRKLSMIILLLLSAVFFMLVNVCTTMFGFTVLLFLLRSLVSMNFNVVYIYTAEVYPTSVRSLGMGFCTSFSRIGGMIAPFIAQVLMSKSVLLALSPFSLACCLCAVGTA------LLPIETRGRAL 457          

Query:   85 SMSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYG-------------WRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMN 768
            ++S     A   ++I    G G F  ++ ++ G      +VE  +++F  P    D  +S  E   + + +F+GM  G+ ++G +SDK GR+  ++ +       +  S+ +    + I  R F G  IGG   +VY+Y +E + +D+RG  +  + +FW MG  Y S     IVP YG             WR ++++   P +  ++    + ESPR+L+   + ++A  ++ ++   N
Sbjct:   86 AVSEQEELAEQYEDIMEDCGHGRFQWSLFVVLGLALMADSVECFVVAFALPSAEKDMCLSNAEKGMLGLIVFLGMMFGAFIWGGMSDKVGRRKCLIIALAINCVSAFLSSFAQGYGFFIFFRLFSGIGIGGSVPIVYSYFSEFLQMDKRGEHLSWLCMFWMMGGIYASFTAWGIVPRYGWGFSMGSEFQFHSWRVFVLVCALPAIAALIGLMFMPESPRFLLEHAKHDEAWMILKQVHDTN 326          

Query:   85 SMSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYG-------------WRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMN-----NADRVTKIKYTEYKQSSVKDMFH 837
            ++S     A   ++I    G G F  ++ ++ G      +VE  +++F  P    D  +S  E   + + +F+GM  G+ ++G +SDK GR+  ++ +       +  S+ +    + I  R F G  IGG   +VY+Y +E + +D+RG  +  + +FW MG  Y S     IVP YG             WR ++++   P +  ++    + ESPR+L+   + ++A  ++ ++   N       +RV  +   +  ++   + F 
Sbjct:   86 AVSEQEELAEQYEDIMEDCGHGRFQWSLFVVLGLALMADSVECFVVAFALPSAEKDMCLSNAEKGMLGLIVFLGMMFGAFIWGGMSDKVGRRKCLIIALAINCVSAFLSSFAQGYGFFIFFRLFSGIGIGGSVPIVYSYFSEFLQMDKRGEHLSWLCMFWMMGGIYASFTAWGIVPRYGWGFSMGSEFQFHSWRVFVLVCALPAIAALIGLMFMPESPRFLLEHAKHDEAWMILKQVHDTNWRAKGEPERVFTVSQIKTPKTQEDEFFE 354          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLL-ESPRYLMIKNRVNDAVKVVNKIAKMNNA--DRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSE--VFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQ 1485
            +++    +GFG FH+ +L I G      ++E +LLS + P + C+W++   + + +T  +F G  L S   G L+D+YGR  V++       Y+S  S+ SPT  W +  R  +G  IGG  +  +  M+E M    RG  +   Q+FW +GS    +L  +I+P  GW + + IS  P   V+L +F+ + ES RY +   + + A+  + KIAKMN     + T ++    ++ ++ D+    Y+ +T     I F + +++YG +  SS +      C  D  T +      +       C        KT+L+S  GE ++     + I  + R+  + +  ++  L+Y L+N C +   + +L+ F R  A T   +  +Y  E  V+PTNIRS  +G  +S AR GAM + F+  +++   S      LF  +     +L F LP ET  R + +
Sbjct:   34 VEQAVEHMGFGRFHILLLFIMGSTTIAESMEIMLLSVISPTIQCEWRLQQWQVALVTTMVFFGFMLSSGPCGFLADRYGRWKVLLLVTIWSSYWSGISSFSPTYGWFVFLRFLMGCGIGG-QSQGFVLMSEFMPSTARGRVLPMSQVFWVLGSLLEVVLAYLILPTLGWAWLIRISTIPSF-VLLIAFKFIPESARYQVSAAKPDKALLTLAKIAKMNKTTLPQGTLVEPPAERRGNIWDLLDRQYLRTTLQTWPIWFGTTLTYYGLILVSSELLERNQMCGDDSVTAIEEHIAFSEQESPCFCKQFKSEDYKTLLLSSFGEFLAIPFTTLTIDTLGRRRSMALSMILCGLLYYLLNICTTRMGLTVLLFFLRAVASTNFNIIYIYTVEVKVYPTNIRSLGLGSCSSTARIGAMIAPFVAQVIL-DISIPLALCLFGTVCVICSVLAFTLPIETMGREMKE 491          

Query:  109 AIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFF----IGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRF----------W----LIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADR 780
            A   + +  + G G F  T  ++ G       VE  +++F+ P    D  I+     ++   +++GM +GS+V+G L+D+ GR+  ++ +   +   S+FS LS +  W   T  F  F     IGG   +VY+Y  E +  D+RG  +  + + W  G  Y S +   I+P YGW F          W    ++ ++  +  +V  +F + ESPR+L+   + ++A  ++ ++   N   R
Sbjct:  149 AQQYEAVMQECGHGRFQWTFYMVLGLALMADGVEVFVVAFVLPSAERDLCITDAGKGWLGTLVYLGMMMGSLVWGGLADQQGRRQCLLMA---LTVNSLFSFLS-SFVWDYGTFIFCRFLDGFGIGGIIPIVYSYYAEFLAHDKRGEHLSWLCMTWMFGGIYASAMAWAIIPHYGWSFGMGSAYQFHSWRVFVIVCALPAVASIVCLTF-MPESPRHLLEMGKHDEAWMILKRVHDTNMKAR 385          

Query:  241 LICD--WKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIK--YTEYKQSSVK 825
            L+C+  W + L +A      L VG+ +G+++ G +SD+YGR+  ++ S      F +  A +P     +  R   G F  G  T V+   TE +   QR    + +Q+F+S G   + +L+ +   L  WR+  +    P +++  + + L ESPR+L+ +NR   A  V+ KIA +N  +    I+  + E  ++  K
Sbjct:  148 LVCENAWLLDLSQA-----LLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFG---VIMLSGIAYYLRTWRYLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDNIRKNFEEVTRADEK 338          

Query:  205 VETVLLSFLGPILICDWKISLLEASFITMALF-VGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNN 771
             ETV+  +    L+C+ K      + +++ LF  G+ LGS+VFG LSD+YGR+  ++ S          +A +P+       R  +G  + G      +   E +    R  +       WS G+  + LL  +   L GW+   ++  SP+   +L  + + ESPR+L+++ R  +A + ++  A++N 
Sbjct:  123 TETVVTQW---DLVCEHKA----LNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWLDQGHRTFAGTSGGFAWSTGNMALGLLAYL---LRGWQQLQLVVTSPIYFCILTWWFIPESPRWLLVRGRAREAHRNLSLCARING 302          

Query:  454 FIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRF----------W----LIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADR--------VTKIKYTEYKQSSVKDM 831
            FI   IGG + +V++Y  E ++ ++RG  +  + +F  +G  Y S +   I+P YGW F          W    ++ ++  +  VV  +F + ESPR+L+   + ++A  V+ ++   N   R        VT+IK  + +   V+ M
Sbjct:   14 FISRSIGGAAPIVFSYFGEFLSREKRGEHLSWLCMFGMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPAVSAVVALTF-MPESPRFLLQMGKHDEAWMVLKQVHDTNMRARGHPERVFTVTQIKTLKQEDELVEMM 160          

Query:  277 SFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSAL---SPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQ--LFW--------SMGSYYISLLTVVIVPL---YGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVK 741
            SF+++  F     G++    +SD YGRK  ++ S   IF FSI ++L   +  I  +I+ R   G  IG  S +V  Y  E      RG  +   Q  + W        S G++  +  +   +P+   Y W  +L I +          F L ESPRY ++K+++++A K
Sbjct:  148 SFLSLGTF----FGALTAPFISDSYGRKPTIIFST--IFIFSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFLAIGM----------FFLPESPRYYVLKDKLDEAAK 302          

Query:  268 LEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWII---MTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMG---SYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADR 780
            L+   +  +  +G  +G  +   ++D++ R   +     GI  ++I + L+  I+ I+   + R   G  +G FS +V +Y  E++   +RG+++  +QL  ++G    +Y+ +   +    + +R    I I P L+  + S+ L ES  +L++  ++++A ++ + +AK  N  +
Sbjct:   65 LQQGLLMGSTPLGGIMGCFICCIMNDRFSR---IYQFQSGIIIWNIVTLLNFCIWDILGLLICRMIKGMILGNFSILVASYANEVIPRGKRGSTMSYIQLCLTIGILVMHYLCIALSLWDSHFAFRIAWCIGIIPGLLFWMASYALPESYHWLVLHGKMSEAQEIQHNLAKKFNESQ 238          

Query:  301 VGMTLGSMVFGTLSDKYGRKV----VVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMG---SYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNAD 777
            +G   G +  G L D YGR++    VV+    GI    I  A S   +   + R   G  +GG + +  T ++E      RGT V   QL  ++G    Y  +  T        WR  L ++ +  + ++     + ESPR+L+ K R  DA + + K  K+   D
Sbjct:  115 IGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIV---IQIASSDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIED 277          

Query:  259 ISLLEASF--ITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSF-RLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKD 828
            I+L ++ +  IT    +G   GS   G  +++YGRK V + ++      S+    S +   ++  R  +G   G    +   ++ EI  ++ RG      Q+  ++G      L +     Y WR WL+ S S + +  + ++ ++ ESPR+L+    V++A   + K+          +I+  +      +D
Sbjct:   80 IALTDSQYGAITSIFSIGGLFGSYYAGNWANRYGRKYVSMGASAMCMVSSLLLFFSNSYLQLLFGRFLVGMSCGTAIVITPLFINEIAPVEWRGAMGSMNQVSINLGILLTQTLALKYADSYNWR-WLLFSGSVIAVANILAWLKVDESPRWLVSHGFVSEAETALFKLRPGTYQQAKQEIQDWQRSHGHNRD 271          

Query:   76 IDFSMSYTTNPAI-PLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVT---KIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTN----HSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSE-VFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDR 1473
            + FS+S      +  + +    IGFG F + ++L+ G+     A+E +LLS L P + C ++IS  + ++IT  +F+GM +GS  +G ++D +GRK V+V  +  I YF + SA SP  +WII+ R  +G  IGG +    T M+E +    R   +     +W++GS +   + ++++P+YGWR+ L +   PM + +L S  L ES R+ +     + A+  ++++A+ N A   T   K      K+  + D+  P    +T +  ++ F    ++YG V                M + L  S           D  C C  +T      ++ +   E+   L+ IVL++ + R+  L +L+ + A  Y+L+  C     +   +   RG    +     +Y  E V P    +  +G  ++ AR GAM + FI  +L+ + S      ++ A   +  ++   LP ETK R
Sbjct:    6 LHFSVSLECGEDVYSVSDAVDHIGFGWFQIKIMLLLGYFSAADALEMMLLSILAPTIRCIFRISAWKEAWITTVVFIGMMVGSSTWGWIADNFGRKFVIVLVSIWIAYFGLLSAFSPHYYWIIVLRMVVGLGIGG-APQSATLMSEFLPSKYRAMCMCIQSPWWTLGSLFTICVAMLVMPVYGWRYLLALLSLPMFLFLLLSPFLPESCRFQLASGDRDKALATLHRMARANKATLPTGFLKDANQNAKRGRILDLLKPELRRTTLMLWFLWFNVAFTYYGVVL---------------MTSELFQSDSAGGGKCEVKDPHCGCKLLTTKDYTDMMWTTLAEIPIVLVNIVLLERLGRRRTLALLYGLTATFYMLLFICTKREWMVAFIFGARGCISGVFTAIYIYTPEVVLPYRGATLGLGTCSAVARIGAMITPFICQVLL-RASVDFALGVYAATGLSCVVIALCLPIETKGR 464          

Query:  202 AVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNAD----RVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPP------------VTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNV----GILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKY--SYLAGTLLFCAINTAGFLLIFLLPFETKDRAL 1479
            A+E  +LS L P + C+W +S+++ + IT  +F+   +GS   G + D +GRK +++ S+  + Y  + SA SP+  W++  R  +GF +GG   +    + E   I  RG +V+ + + W++GS+  SL+ +V VP  GWR +++    P+++ ++ S  + E   +L+     ++A KV+ ++A++  A+     +  + + E     V D+  P Y  +T + +Y  +   +S+ G  +   ++                    T   T  S CP             ++ N   T+L + + EL + ++ + +   V RK  L   F+I ++ Y  +  C + S V     + ++ G   AG    V + Y SEV+PT  R+  +GL N   R G + +  I  +L      + +   LLF A+ T   +  + LP ET+ R L
Sbjct:    4 AMEITMLSILVPYVKCEWDLSIVQVAMITTVVFIMFLVGSPTLGWMGDNFGRKPMLIVSSVAVAYAGLLSAFSPSYPWLLFLRGIVGFGLGG-KCLNAALLVEYSPIKHRGATVMSLGVAWAIGSFMTSLVGMVFVPWLGWRSFVVAITFPLVVFLILSKWIPEFSHFLITSGEKDEARKVLQEMARIQKAELPIGELQGLSH-EVALGRVGDLLTPEYRLTTLLLIYFYYFYLLSYRGIYYGLVLLT-------------------TQIMTSGSHCPGSVKFKTKLYTILLSTNDFTTLLWTTSAELPAMILTLAMADKVGRKTLLTTYFVIASICYCFLFIC-AGSRVFLAFNLFIIRGLLLAGN--EVLICYTSEVYPTAFRATGLGLMNGIGRIGGVIAPLISQVLADSSMNAAIGVLLLFTALCT---VTCYFLPIETRQREL 424          

Query:  139 IGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFIT--MALFVGMTLGSMVFGTLSDKYGRKVVVV--------TSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTM-VYTYMTEIMTIDQRGTSVICVQL------------FWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVT---KIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSC-CPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQS 1488
            I FG F   ++ I GF     A+E +LLS L P + C W ++ LE +FIT  + +FV +            ++  K  +V         S   I++F +  +L   + + I  RC    F G   T+ +Y    E+   D    SV CV L            FW++GS +   + + ++P  GWR+ L I   P+L+ +  S  L ES R+L+       A++V+  + +MN         K      K+  V D+F  +   +T +   I F    ++YG V +++          Q + T    +    HS+ + C C  +       ++ +   E    +I + +I  + RK    + F+I A+ + L+  C     + I +   RG+     +   +Y  EV+PT  R+  +G  +  AR GAM + F+  +L+ K S      ++  ++    +   +LP ETK R +  S
Sbjct:   21 IRFGPFQARLIAIVGFFVIADALEMMLLSILAPTIRCTWHLNSLEEAFITTYIPVFVLIMFSVQTGNIQKSRWRPKGTIVLNRMQGNTKSIISIYHFLLGLSLRDILGYSI--RCVTLVFWGEARTVSLYVIFDELSLRDILRCSVRCVTLVFWGTRKVSLYIFWAVGSTFTVAVAMAVMPTLGWRWLLAILCLPLLLFLAMSKWLPESCRFLLAAGEREGAIQVLRDMCEMNKKQMPQGELKDASQNAKRGRVADLFLKDQWKTTILLWIIWFNLAFAYYGIVLTTT-------ELFQTISTEGKCASSGKHSSKADCGCQLLGVEDYVDMMWTTLAEFPGVIITMFIIDKLGRKYTAALEFVITAVFFFLLIICTDRLTMTIFIFIVRGAISGAFQTFYVYTPEVYPTVTRALGLGCCSGIARVGAMITPFVAQVLL-KESVALSMGVYGGMSVICIIASLMLPIETKGREMQVS 487          

Query:  250 DWKISLLEASFITMAL----FVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVV---NKIAKMNNADRVTKIKYTEY-KQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQ-DMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYL-------------IGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILM----MFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVED 1497
             W + L E S+I+  +    FVG   GS + GT+SD +GRK+ +  S        I ++   +   +I+   F G  +       YT + E++  D R  + I  +LFW  G   I L+   I     WR +++I  +P L ++LF   + ESPR+L+ K R+++A +++      +K    D+ +  +  E  ++S VK                                     +  R  Q DM       K+T     + C   ++       + S+ G+L   L             +G ++ K+ RR I++  + L  AL   ++     PS   +LM    +  RG  G +     L  SE++PT IR+ +IG   +FAR G + + +++ ML+++ S     +LF  +     +  F +P ET    L QSVE+
Sbjct:   13 QWNL-LCERSYISALVQSMYFVGYLFGSFLSGTVSDAFGRKITLTVSVALQAAAFIGASFVTSHIALIILLFFAGLSLASSIACQYTLIIEMIGPDHRTIAGIINELFWKAGWLLIILVAYFI---RDWRIFMLIGAAPGLAILLFWKWIFESPRWLLTKGRLDEAHEILVNFGGKSKEQPLDKNSLRQLIERIRESQVKR---------------------------------EGEVTKRHTQLDMVRTPKMRKFTLVMAINWCTVALSSYGFTLFMSSLAGDLYLNLVYSAILPTLLLPVVGCLIAKFGRRLIHIIFMALSGALCIGILGV---PSGYPLLMTGLALTARGVIGALWTTIYLITSELYPTTIRNTAIGTCATFARIGGLVAPYVI-MLVMRVSLYLPVILFGCLCILAAIAFFFIP-ETLKVPLAQSVEE 412          

Query:  295 LFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISI---SPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNAD 777
            +F G   G++VFG LSDKYGR+ V+  S+C + + +  S+  P  +   + R FIGF +GG   +++   TE +   +R  +      FW+     I+LL   I      R W I+SI   +P +++ LF + + ES R+L+   R  +A  ++ K+ K N  +
Sbjct:   23 MFTGWLFGNIVFGILSDKYGRRKVLFISSCMVCWVAFASSFVPYYWLYAVFRFFIGFGLGGSIVILFIMATEFVGPQKRAMAGTFTWYFWTGALMLIALLAYFI------RDWRILSITTSAPGILLFLFWWLIPESVRWLLTHERSKEAEMILRKVGKFNKHE 180          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSS---VKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTL-LFCAINTAGFLLIFLLPFETKDRALPQS 1488
            +D+    IGFG+F   + LI G      A+E ++LS LGP L CDW +   + + IT  +F+GM  GS V+G +SDKYGRKV +    C   Y+ I SA +P   W+++ R F+GF IGG    V  Y TE + +  RG  ++ +  FW++G+ +  LL + ++P  GWR+ L +S  PM + V F F L ESPR+ ++  R   A+  + +IAK +N   + +   T YKQ++   +KD+F P Y  +T +  ++ F +  S+YG V  ++ +      C +     + P            C  ++ +  K +L +   E    L+ ++ I Y+ RK  + + F + +L  L +  C+    + I +   R       +V  +Y  EV+PT  R+ ++G  ++ AR GA+ + F+  +L+ +  Y+  TL ++CA      +   LLP ET  R L +S
Sbjct:   73 VDDALEAIGFGVFQWKISLITGLAWVADAMEMMILSILGPELHCDWSLPSYQVALITSVVFIGMGFGSPVWGNVSDKYGRKVGLTVCMCWTLYYGILSAFAPIYGWLLVLRGFVGFGIGGAPQSVTLY-TEFLPVKARGICIVLIGAFWAIGAVFEVLLALWVMPTLGWRWLLGLSALPMAVFVCFCFWLPESPRFDVLAGRREKAMATLVRIAK-DNGKAMPQGTLTIYKQTNRGQLKDLFSPQYWKTTLLLWFLWFANAFSYYGIVLLTTELFQAGDLCAETQGAKIEPRCSLE-------CKYLSSDDYKDLLWTTLAEFPGLLVILLAIDYMGRKKSMALCFFMFSLCILPLFACIGRIALTIFIFICRAFISGGYQVVFVYTPEVYPTETRALAMGTSSAIARIGALITPFVAQVLLRRSVYV--TLGVYCACGLVAGIASLLLPIETLGRGLQES 522          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLL-ESPRYLMIKNRVNDAVKVVNKIAKMNNAD--RVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIK-----YSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQS 1488
            +++   +IGFG FHV + +I G      A+E +LL+ + P + C+WK+   + + ++  +F+G  +  ++ G ++D++GR  VV        YFS+ ++ +P+  W I  R  +G  + G S   +   TE +    R   +    +FW MGS  I +L +++VP  GWR+ + IS++P  IV++F F+ + ES RY +    V+ A+K + +IA+MN A       ++     + S + +  P++  ++ +  Y  FV+  ++YG V SSS +      C+ + +   H  K+  H      C P  +   +T+LIS  GE+    + I L+    RK  L +L L+ ALV++++N C +     +L+   R        V  +Y +EV+PT  RS  +G   SF+R G M + FI  +LM K      S  A   + CA+        FLLP ET+ RAL Q+
Sbjct:   52 VEDAVEEIGFGRFHVLLFVIMGSANVVEAMEIMLLAVVSPEIRCEWKLDDWQVALVSTIVFLGFMVCGVLSGYMADRFGRWKVVFGGFVWSAYFSLLTSFAPSYGWFIFLRSMVGCGVAGVSQG-FVLKTEFIPAKYRAVLLPLATIFWMMGSMLIIVLGMLVVPTLGWRWMIRISVTPS-IVLIFLFKFIPESARYNVSAGNVDAALKTLQRIARMNRAGLPEGRLVEPAVRNRGSWRILLSPSFRRTSLLLWYSWFVASFAYYGSVLSSSELLEKNLLCVTNAER-EHQVKH-RHQGGVCYCIPFGYGDYQTLLISCLGEVALVPLNIALLNVFGRKTSLSVLQLLAALVFMMLNICSTMLGFTVLLFLLRSLVSMNFNVVYIYTAEVYPTVARSLGMGFCTSFSRIGGMIAPFIAQVLMSKSVVLALSPFAVACVICALGN------FLLPIETRGRALLQN 506          

Query:  100 TNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTK--IKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRC---LQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISK 1509
            T+    +++    IGFG F   + ++ G      A+E ++LS L P L C+W++  LE + +T A+F+GM + S ++G +SDKYGRK  +  S     ++ I SA +P   WI++ R  +GF IGG    V  Y  E + +  R T ++ +++FW++G+ +  LL ++++P  GWR+ L +S  P+ I  +  F L ES RY ++    + A+  + +IA  N         I   +  +  +KD+F  ++  +T +  +I F +  S+YG V  ++ +      C    Q+++  L              C  +T +  K +L +   E    L+ +  I  + R+  + + FLI +L  + +  C+   ++ +L+   R       +   +Y  EV+PT  R+  +G  +  AR GA+ + F+   +M++YS      ++C       +    LP ET  R L ++   +  +
Sbjct:   62 TDDTFMVEDAVEAIGFGTFQWKLSILTGLSWMADAMEMMILSILAPQLHCEWRLPSLEVALLTSAVFIGMMISSSLWGNISDKYGRKTGLKMSVLWTMFYGILSAFAPIYGWILVLRALVGFGIGGAPQSVTLY-AEFLPMRSRATCILLIEIFWALGTVFEVLLAILVMPTLGWRWLLGLSTIPLFIFAILCFWLPESARYDVLTGNQDKALATLKRIATENGVPMPLGKLIAARQEDRGKIKDLFSSHFRCTTVLLWFIWFANAFSYYGLVLLTTELFQEGGACGRNKQELRCNLE-------------CKYLTSDDYKDLLWTTLSEFPGLLVTLWAIDRLGRRRTMALCFLIFSLALIPLYGCVGRVSMMVLIFIARAFIAGGFQAAYVYTPEVYPTATRALGLGTSSGMARVGALITPFVAQ-VMLEYSVYLALSVYCCCCLLAAVASCALPIETTGRGLQEASHREWGQ 521          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLL-ESPRYLMIKNRVNDAVKVVNKIAKMNNAD--RVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIK-----YSYLAGTLLFCAINTAGFLLIFLLPFETKDRA 1476
            +++   +IGFG FHV + +I G      A+E +LL+ + P + C+WK+   + + ++  +F+G  +  ++ G ++D++GR  VV        YFS+ ++ +P+  W I  R  +G  + G S   +   TE +    R   +    +FW MGS  I +L +++VP  GWR+ + IS++P  IV++F F+ + ES RY +    V+ A+K + +IA+MN A       ++     + S + +  P++  ++ +  Y  FV+  ++YG V SSS +      C+ + +   H  K+  H      C P  +   +T+LIS  GE+    + I L+    RK  L +L L+ ALV++++N C +     +L+   R        V  +Y +EV+PT  RS  +G   SF+R G M + FI  +LM K      S  A   + CA+        FLLP ET+  A
Sbjct:   55 VEDAVEEIGFGRFHVLLFVIMGSANVVEAMEIMLLAVVSPEIRCEWKLDDWQVALVSTIVFLGFMVCGVLSGYMADRFGRWKVVFGGFVWSAYFSLLTSFAPSYGWFIFLRSMVGCGVAGVSQG-FVLKTEFIPAKYRAVLLPLATIFWMMGSMLIIVLGMLVVPTLGWRWMIRISVTPS-IVLIFLFKFIPESARYNVSAGNVDAALKTLQRIARMNRAGLPEGRLVEPAVRNRGSWRILLSPSFRRTSLLLWYSWFVASFAYYGSVLSSSELLEKNLLCVTNAER-EHQVKH-RHQGGVCYCIPFGYGDYQTLLISCLGEVALVPLNIALLNVFGRKTSLSVLQLLAALVFMMLNICSTMLGFTVLLFLLRSLVSMNFNVVYIYTAEVYPTVARSLGMGFCTSFSRIGGMIAPFIAQVLMSKSVVLALSPFAVACVICALGN------FLLPIETRGHA 505          

Query:  121 DEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYG-------------WRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMN 768
            + I    G G F   +  + G       V+  ++ F+ P    D  IS  +   + + ++V M +G++V+G L DK GR+  ++        FS  S  +    + +  R   GF IGG   +VYTY TE + +D+RG  +  + +FW +G  Y S     I+P YG             WR ++++ + P L  ++    + ESPR+L+   R ++A  ++ ++   N
Sbjct:  104 ESIMEDCGHGRFQWMLFFVLGLALMADGVDGFVVGFVLPSAEKDMCISNADKGLLGLLVYVAMMVGALVWGGLCDKMGRRKCLIYVLTIDLVFSFLSCFAQGYGFFLFLRICSGFGIGGSIPIVYTYFTEFLQMDKRGEHLSWLCMFWMLGGLYASFTAWGIIPHYGWGFAIGTQFQIHSWRVFILVCLFPALAALIGVVFMPESPRFLLENARHDEAWMILRRVHDTN 332          

Query:   88 MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLELLIKNQ 1533
            MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICFVSGISFYGFVFSSSVVNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSF+VNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLELLIKNQ
Sbjct:    1 MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICFVSGISFYGFVFSSSVVNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFMVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLELLIKNQ 482          

Query:   97 TTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLELLIKN 1530
            ++NP   L++I+ KIGFG FHV V+LIFGF+QFFYAVETVLLSFLGPILIC WKISLLE+S ITMA+FVGM++GS++FG LSD YGRK++V+TS+CGIFYFS+  A SP + W+++ R  IG FIGGFSTM YTYMTE+MT  QRGTSVICVQ+FWSMGSYYIS+LT+ IVP YGWR WL+++I+PM ++V+ S  L ESPRYL+++N   +A+K++NKIAKMN A+ V  +K    K SS KD+FH NY  ST ICMYICFVSGISFYG VFSSSVVNHIPH+CLQDM   L+P  Y N S D SCC   TW+T+KTV+ISITGEL SY+IGI +IKY++RK+YLQIL LINA V+ LMN CLSP+  GILMMFGRGS GTILRVNLLY+SEVFPTNIRSF+IGLGN F R GAMFS+F+VN+LMI+YS+L GTL +CAIN  G +L+F+LP+ETKDRALPQ+V+DDI+K +  +K 
Sbjct:    6 SSNPL--LEDIFSKIGFGRFHVMVILIFGFIQFFYAVETVLLSFLGPILICTWKISLLESSVITMAVFVGMSIGSLIFGKLSDIYGRKIIVLTSSCGIFYFSVLCAGSPNVIWVVIIRGIIGLFIGGFSTMFYTYMTEVMTTKQRGTSVICVQIFWSMGSYYISILTLAIVPEYGWRLWLVLTIAPMSVIVMLSLWLPESPRYLLLRNETREALKIINKIAKMNKAEYVPSVKNPVNKTSSWKDIFHRNYFLSTIICMYICFVSGISFYGIVFSSSVVNHIPHKCLQDMDQTLNPLLYQNSSADHSCCFTQTWHTMKTVIISITGELSSYVIGIFVIKYIKRKLYLQILLLINASVFFLMNLCLSPTENGILMMFGRGSGGTILRVNLLYISEVFPTNIRSFTIGLGNCFVRLGAMFSTFVVNLLMIQYSFLTGTLFYCAINLVGVILVFILPYETKDRALPQNVDDDINKFDQPMKQ 481          

Query:   88 MSYTTNPAIPLDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLELL 1521
            MS T +    LD+I+ KIGFG FHV +++IFGF+QFF + E V  +FLGP LIC+W+ISLLE+S +T+++F+GM  GS+ FG LSD YGRK +++    GI +F +  + SPT+ W+IM R  IG FIGG++TM+ T++ EIM I+ RG + +CVQ  WS+GS+YI+LLT+++VP +GW+ WLI SI P++I +     L ESPRYL++KN+  +A+ V+N IA +NN+++++ ++   YK+ +  D+FH +Y  +T I  +I F+SG +FYGF+ SSS++N IPH+CLQ++    +PS +T  S D+SCC   +W+T++TV ISITGE+  +L+GI++IK+++RK++LQ+L +INA+VY+L+N CLS SN+GILMMFGRG+A  ++ VN LY+SEVFPTN RSFSIG  N F R GA+FSSFIV++LM+ +S+   T+ +  +NT GFL IFLLPFETK+RAL QSV+++IS+L+L+
Sbjct:    1 MSKTDSLCPSLDDIFLKIGFGKFHVLIIIIFGFIQFFTSAEIVSSAFLGPSLICNWEISLLESSIVTLSVFIGMICGSLFFGKLSDAYGRKTIIIICVYGILFFGLLCSASPTVHWVIMLRFIIGIFIGGYTTMLVTFLAEIMPINYRGLASLCVQTSWSLGSFYIALLTILLVPKFGWKIWLICSILPIVIAIPLIIWLPESPRYLLLKNKTKEAINVMNIIATINNSEKISCVQTDAYKKPAYCDLFHKHYARTTIITAFISFISGNNFYGFILSSSIINDIPHKCLQNLNQTFNPSMFTKASLDNSCCFNQSWDTMQTVFISITGEVGFFLLGILIIKFMKRKLFLQVLLVINAVVYVLLNLCLSSSNIGILMMFGRGAAAIMIGVNNLYVSEVFPTNNRSFSIGFTNGFTRLGAIFSSFIVDILMVNHSFTGCTIYYFTLNTIGFLFIFLLPFETKNRALLQSVDENISELQLI 478          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSS-VKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKYTNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVEDDISKLEL 1518
            LDE+  KIGFG FH   ++I GF+Q F A+E +LLSF+GP+L C WKI+L ++SFIT+++F+GM  G+++FG+LSDK+GRK +++    GIFYFS+  ALSP+  WI+++R  IG FI G      T++ EIM I  RG + +CVQ FWS+GSYYISLLT+++VP YGWR WL+IS  PM+ ++     L ESPRYL++ NR ++A+KV+N IA MN AD V+ +   + K SS +KD+FHP Y+ +T IC YICFV+G S+YG+V SSS++N+IPH CLQ++  +   S YTN S D SCC   TW+T+ TV ISI GE +SY+ GI  I+++ RK+Y+ ++ LI A+VY L+N CLSP+  GILMMFGRG+A  ++ +  +YMSEV+PT+IRSF +GL ++F R GA+ S  +VN +M+  S+LA T+++  +N  G  L+F LPFETK+R + QSVE++IS++ +
Sbjct:   11 LDEVTLKIGFGKFHTISIIILGFIQCFEAIEIILLSFIGPLLTCAWKINLFQSSFITVSVFLGMIFGALLFGSLSDKHGRKTILLICFVGIFYFSLLCALSPSFIWILISRAAIGIFIAGSVVTTPTFLAEIMPISHRGIAQMCVQTFWSLGSYYISLLTIILVPRYGWRLWLVISACPMIFILPAIIWLPESPRYLLLVNRKDEAIKVINYIASMNGADPVSDVNIIKQKSSSTIKDIFHPTYLITTVICAYICFVAGTSYYGYVLSSSIINNIPHNCLQNLPLLSDISLYTNSSIDDSCCFFQTWDTMNTVFISIAGEFMSYIFGIFCIRFIYRKMYIFMMLLIIAIVYFLLNLCLSPTYTGILMMFGRGAAVILISLEYIYMSEVYPTSIRSFGVGLCSNFIRIGAVVSPIMVNGIMVNLSFLASTMVYSGLNLFGLFLVFFLPFETKNRPVLQSVEEEISEISV 478          

Query:  118 LDEIYGKIGFGLFHVTVLLIFGFVQFFYAVETVLLSFLGPILICDWKISLLEASFITMALFVGMTLGSMVFGTLSDKYGRKVVVVTSACGIFYFSIFSALSPTIFWIIMTRCFIGFFIGGFSTMVYTYMTEIMTIDQRGTSVICVQLFWSMGSYYISLLTVVIVPLYGWRFWLIISISPMLIVVLFSFRLLESPRYLMIKNRVNDAVKVVNKIAKMNNADRVTKIKYTEYKQSSVKDMFHPNYISSTFICMYICXXXXXXXXXXXXXXXXXNHIPHRCLQDMKTILHPSKY--TNHSTDSSCCPPVTWNTIKTVLISITGELISYLIGIVLIKYVRRKIYLQILFLINALVYLLMNFCLSPSNVGILMMFGRGSAGTILRVNLLYMSEVFPTNIRSFSIGLGNSFARTGAMFSSFIVNMLMIKYSYLAGTLLFCAINTAGFLLIFLLPFETKDRALPQSVED 1497
            ++    KIG G FH+ ++L  G +    ++E ++L+FLGPIL C W+IS++EASF+T A+F+G+ +G+ + G  SD++GRK+ ++ +   + YF +F A SPT++WII+ RC IG  IGG +  +Y+ ++E+  +  RGT  + +Q FW+ GS  I+LL  +IV  YGWR +L +S  P++IV++  F + ESPRYL+++N+ + A++++NKIA +N+++ +T +       SS KD+ H NY+ +TF   +I   +G+S+Y  +    ++  IPH+CLQ+ KT    S     N + D SCC  + W++ K + IS  GE++   I I+LI YV RK  L I  L+ ++    +NFC+S   +  ++   RG+  ++  V  +Y +EV+PT++RS S+G+G+SF+R GA+ S F VN+L  +YS+  GT+L    N  G ++ F LP+ETKDR L Q+ + 
Sbjct:    7 IESALSKIGLGKFHLILMLTLGLIHSCDSMEMLILAFLGPILSCHWRISVIEASFLTTAVFLGIIVGNSLLGKFSDRFGRKMTLILTNSCLLYFGLFCAASPTVYWIIILRCLIGVCIGGNNCNIYSLLSEMSPVQYRGTLQVLLQFFWACGSLIITLLCFLIVHKYGWRLFLSLSTIPVIIVLVSLFWIYESPRYLLLRNQKSKALEIINKIAVINHSEIITDLCNQPVLTSSFKDLIHSNYLLTTFYTSFIWLNTGLSYYSTILIVPIIMGIPHQCLQNWKTFSQLSIQINVNKTVDDSCCFEMNWDSYKNMFISTAGEIVVIPISIILINYVGRKRTLSIYMLVISIGTFCLNFCMSSLALSAVLFIIRGAVKSLYNVIFIYCAEVYPTSVRSLSLGMGSSFSRIGAIISPFFVNILFAQYSFFGGTMLLALTNAIGLVISFFLPYETKDRELFQTADH 468