Sorting nexin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30011933 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Sorting nexin vs. Ensembl Human
Match: SNX18 (sorting nexin 18 [Source:HGNC Symbol;Acc:HGNC:19245]) HSP 1 Score: 234.572 bits (597), Expect = 8.050e-68 Identity = 137/396 (34.60%), Postives = 203/396 (51.26%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDS------QF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL---SVKDKDKWTNGKREIEKDYHKSGRFYCAVE-APVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
+F+K+GGE F+LG A + D K V P G F CTI K +KFKGMK++I+Y+L ++T+ + RRYK FDWL+++L+EK+P I +P LP KQ GR+E++FI RRK L W+ H+ SHPVLA +HFL S D+ W GKR+ EKD F+ + P ++ + +I+ F + + L N F ++Q KE+QK+G S LS++ L D + + L + TGD YD IG+LF +Q + D D V D L G + P +I + K A+ V+ S R E K+ ++ +GI I+ AE++ R + +S M +LQ QI + +T L EAL
Sbjct: 234 TFVKSGGEAFVLGEAS---------GFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL--DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEAL 618
BLAST of Sorting nexin vs. Ensembl Human
Match: SNX33 (sorting nexin 33 [Source:HGNC Symbol;Acc:HGNC:28468]) HSP 1 Score: 222.631 bits (566), Expect = 8.442e-64 Identity = 124/391 (31.71%), Postives = 199/391 (50.90%), Query Frame = 3
Query: 420 FLKNGGEEFLLG----LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
F+++G E F+LG +AK++ T ++ WK C++ K +KFKG+K++I+Y+L ++ + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFLS D +W GKR EKD F + P + + D R++ F + L V + ++ G KEFQK+GS+ +S S + P S+ +L + TG Y+ IG++F +Q ++D + D L G++ P +I L K A V+ S R S E ++ + +GI R RV+ + AE+N RE + M YL+ QI Y + L + L +
Sbjct: 189 FVRSGVEAFILGDVPMMAKIAETYS------IEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSE--ALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMY 571 HSP 2 Score: 53.9138 bits (128), Expect = 7.666e-7 Identity = 22/57 (38.60%), Postives = 36/57 (63.16%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
++ + +YDF E ++ I+ E +VI + +GW + +N RGE GL PA+YVEI+
Sbjct: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
BLAST of Sorting nexin vs. Ensembl Human
Match: SNX18 (sorting nexin 18 [Source:HGNC Symbol;Acc:HGNC:19245]) HSP 1 Score: 198.749 bits (504), Expect = 1.205e-54 Identity = 127/385 (32.99%), Postives = 192/385 (49.87%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDS------QF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL---SVKDKDKWTNGKREIEKDYHKSGRFYCAVE-APVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNV-------RVITRTVDAELNWLQTEREKQLRSTMVQYL 1517
+F+K+GGE F+LG A + D K V P G F CTI K +KFKGMK++I+Y+L ++T+ + RRYK FDWL+++L+EK+P I +P LP KQ GR+E++FI RRK L W+ H+ SHPVLA +HFL S D+ W GKR+ EKD F+ + P ++ + +I+ F + + L N F ++Q KE+QK+G S LS++ L D + + L + TGD YD IG+LF +Q + D D V D L G + P +I + K +E S C++ T+ + V +R VDA + L+ + + S +++YL
Sbjct: 234 TFVKSGGEAFVLGEAS---------GFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL--DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGKAWPLEQVIW-SVLCRLKGATLTAVPLWVSESYSTGEEASRDVDAWVFSLECKLDCSTGSFLLEYL 606
BLAST of Sorting nexin vs. Ensembl Human
Match: SNX18 (sorting nexin 18 [Source:HGNC Symbol;Acc:HGNC:19245]) HSP 1 Score: 197.208 bits (500), Expect = 2.086e-54 Identity = 115/325 (35.38%), Postives = 168/325 (51.69%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDS------QF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL---SVKDKDKWTNGKREIEKDYHKSGRFYCAVE-APVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVE 1358
+F+K+GGE F+LG A + D K V P G F CTI K +KFKGMK++I+Y+L ++T+ + RRYK FDWL+++L+EK+P I +P LP KQ GR+E++FI RRK L W+ H+ SHPVLA +HFL S D+ W GKR+ EKD F+ + P ++ + +I+ F + + L N F ++Q KE+QK+G S LS++ L D + + L + TGD YD IG+LF +Q + D D V D L G + P +I + K +E
Sbjct: 234 TFVKSGGEAFVLGEAS---------GFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL--DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGKAWPLE 547
BLAST of Sorting nexin vs. Ensembl Human
Match: SNX9 (sorting nexin 9 [Source:HGNC Symbol;Acc:HGNC:14973]) HSP 1 Score: 192.971 bits (489), Expect = 7.933e-53 Identity = 124/418 (29.67%), Postives = 208/418 (49.76%), Query Frame = 3
Query: 333 ASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKY-PCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
A +R + R S + S K+ + P F K G E++LL AK + K+ ++V + V+ S F C + K SK G+K++I YQL + T ++ RYK FDWL+ +L K+ I IP LP+KQV GR+E+ FI+ R + LQ W+T + HPV++ S+ + FL+ +D+ +W GKR+ E+D + +E +++ + ++ E V F + + L V KR +GP+ KE+QKIG ++ +L+ S D++ + G Y+ I L +Q + D + + G + P +I K A+ V+ S + KITL+ + + + V +++ + AE+N + R S + YL+ Q+Q Y I L +ALS F
Sbjct: 186 AGGAQRGNSRAS---SSSMKIPLNKFP-GFAKPGTEQYLL--AKQLAKPKEKIPIIVGDYGPMWVYP---TSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLN--DAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRF 592 HSP 2 Score: 62.7734 bits (151), Expect = 1.505e-9 Identity = 28/57 (49.12%), Postives = 40/57 (70.18%), Query Frame = 3
Query: 48 EAKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+A+V+YDF E + +L + GEII I + DVG GW + RN +GE GL+P +YVEI+
Sbjct: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60
BLAST of Sorting nexin vs. Ensembl Celegans
Match: lst-4 (Sorting nexin lst-4 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4E2]) HSP 1 Score: 242.662 bits (618), Expect = 9.194e-72 Identity = 136/393 (34.61%), Postives = 215/393 (54.71%), Query Frame = 3
Query: 384 SSKVN-TIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTIL 1559
S+KVN I +F+K+G E +++G +K ++ I + EV+++N WKP+ C + K SK KG+K+FI Y + SS T +SRRYK FDWLH QLS KY I IPPLP KQV GRYE++ I+ R+ LQ W+ + HPVL+ S+ HF+S D+ W NGKR EKD + G F + P ++ N+ ++E+ + E+ R++QE N F K +GP+ + +QK+GS+ L +S + D L L T Y IG++F ++D + V +NL + G ++ VP +I++ K AV + +E +++ E + + + ++ TV AE+ E+ + ++STM YL+ Q Y + T L
Sbjct: 173 SNKVNKNINRFSNFVKSGVEAYVIGESKTTSQISERHEVVMNNG--IIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEI--DETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKF-----RDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 556
BLAST of Sorting nexin vs. Ensembl Celegans
Match: lst-4 (Sorting nexin lst-4 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4E2]) HSP 1 Score: 238.81 bits (608), Expect = 6.337e-71 Identity = 136/395 (34.43%), Postives = 216/395 (54.68%), Query Frame = 3
Query: 384 SSKVN-TIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYT--KDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTIL 1559
S+KVN I +F+K+G E +++G +K ++ I + EV+++N WKP+ C + K SK KG+K+FI Y + SS T + +SRRYK FDWLH QLS KY I IPPLP KQV GRYE++ I+ R+ LQ W+ + HPVL+ S+ HF+S D+ W NGKR EKD + G F + P ++ N+ ++E+ + E+ R++QE N F K +GP+ + +QK+GS+ L +S + D L L T Y IG++F ++D + V +NL + G ++ VP +I++ K AV + +E +++ E + + + ++ TV AE+ E+ + ++STM YL+ Q Y + T L
Sbjct: 112 SNKVNKNINRFSNFVKSGVEAYVIGESKTTSQISERHEVVMNNG--IIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQRQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEI--DETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKF-----RDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 497
BLAST of Sorting nexin vs. Ensembl Celegans
Match: lst-4 (Sorting nexin lst-4 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4E2]) HSP 1 Score: 239.195 bits (609), Expect = 1.714e-70 Identity = 136/395 (34.43%), Postives = 216/395 (54.68%), Query Frame = 3
Query: 384 SSKVN-TIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYT--KDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTIL 1559
S+KVN I +F+K+G E +++G +K ++ I + EV+++N WKP+ C + K SK KG+K+FI Y + SS T + +SRRYK FDWLH QLS KY I IPPLP KQV GRYE++ I+ R+ LQ W+ + HPVL+ S+ HF+S D+ W NGKR EKD + G F + P ++ N+ ++E+ + E+ R++QE N F K +GP+ + +QK+GS+ L +S + D L L T Y IG++F ++D + V +NL + G ++ VP +I++ K AV + +E +++ E + + + ++ TV AE+ E+ + ++STM YL+ Q Y + T L
Sbjct: 173 SNKVNKNINRFSNFVKSGVEAYVIGESKTTSQISERHEVVMNNG--IIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQRQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEI--DETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKF-----RDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 558
BLAST of Sorting nexin vs. Ensembl Celegans
Match: lst-4 (Sorting nexin lst-4 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4E2]) HSP 1 Score: 238.424 bits (607), Expect = 4.929e-70 Identity = 136/395 (34.43%), Postives = 216/395 (54.68%), Query Frame = 3
Query: 384 SSKVN-TIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYT--KDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTIL 1559
S+KVN I +F+K+G E +++G +K ++ I + EV+++N WKP+ C + K SK KG+K+FI Y + SS T + +SRRYK FDWLH QLS KY I IPPLP KQV GRYE++ I+ R+ LQ W+ + HPVL+ S+ HF+S D+ W NGKR EKD + G F + P ++ N+ ++E+ + E+ R++QE N F K +GP+ + +QK+GS+ L +S + D L L T Y IG++F ++D + V +NL + G ++ VP +I++ K AV + +E +++ E + + + ++ TV AE+ E+ + ++STM YL+ Q Y + T L
Sbjct: 199 SNKVNKNINRFSNFVKSGVEAYVIGESKTTSQISERHEVVMNNG--IIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQRQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEI--DETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKF-----RDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 584
BLAST of Sorting nexin vs. Ensembl Celegans
Match: lst-4 (Sorting nexin lst-4 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4E2]) HSP 1 Score: 225.713 bits (574), Expect = 8.176e-68 Identity = 121/344 (35.17%), Postives = 186/344 (54.07%), Query Frame = 3
Query: 528 WKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTIL 1559
WKP+ C + K SK KG+K+FI Y + SS T +SRRYK FDWLH QLS KY I IPPLP KQV GRYE++ I+ R+ LQ W+ + HPVL+ S+ HF+S D+ W NGKR EKD + G F + P ++ N+ ++E+ + E+ R++QE N F K +GP+ + +QK+GS+ L +S + D L L T Y IG++F ++D + V +NL + G ++ VP +I++ K AV + +E +++ E + + + ++ TV AE+ E+ + ++STM YL+ Q Y + T L
Sbjct: 8 WKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEI--DETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKF-----RDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 344
BLAST of Sorting nexin vs. Ensembl Fly
Match: SH3PX1 (gene:FBgn0040475 transcript:FBtr0076413) HSP 1 Score: 199.134 bits (505), Expect = 1.336e-55 Identity = 119/410 (29.02%), Postives = 209/410 (50.98%), Query Frame = 3
Query: 354 SQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDK-SSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSL----CPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEA 1568
+Q + + + T++ K + ++LGL+ I + +++ S + ++A K SKFKGMKTFI YQL S+ +SRRYK FDWLH +L +K+ I +PPLP+KQ+ GRYE+ F+E RR LQ+++ V HPV++ + HFL+ +D+ W +GKR+ E+D + + A+ P + + ++E + FI + + R L + N+ KR KEFQ+IG + +L++++++ P N+ + L + R G ++ IG+ F Q + D + D L GV+ P + K A+ + + + E ++ + ++R V++ TV AEL ++ER+ L+ T+ ++ QI+ Y + L EA
Sbjct: 155 TQSLASVAGGTGAAGTVK--KGMFAKSSDSYILGLSSTKEKIPECEMAYITQVEDSIYQWTQNHSPYSVVVASPKKESKFKGMKTFIAYQLTPSFNNISVSRRYKHFDWLHERLVDKFCLIPVPPLPDKQISGRYEEQFVEHRRVQLQEFVDWVCRHPVISKCEVWYHFLTCRDEKIWKSGKRKAERDPYMGVNYCLAISPPDKNLLHSKVDAQVELGTQFIHSMDVAVRNLNNISNDMAKRSMSQSKKEFQRIGDGLSDLAKALAIDERRAPTRNA--VPLSESVGRIGGIFIGIGQAFGDQPKHDWIPLSDRLHIYRGVLNCFPDIFSTHKGAIQKRKDCEKLAGEGRMNNPQLHDVNRRTDVVSYTVLAELTHFKSERDTHLKHTLKNFIAEQIKFYQGVVARLQEA 560 HSP 2 Score: 62.7734 bits (151), Expect = 7.126e-10 Identity = 26/56 (46.43%), Postives = 39/56 (69.64%), Query Frame = 3
Query: 54 KVIYDFTPEQ-PSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIIS 218
+ +YDFT E S+L I +G+++ + DVG GWW+ +N RG+ GL PA YVE++S
Sbjct: 6 RAMYDFTGEPGSSELSIATGDVLSVTRSDVGEGWWEGKNARGQIGLFPAAYVEVMS 61
BLAST of Sorting nexin vs. Ensembl Fly
Match: Snx3 (gene:FBgn0038065 transcript:FBtr0082641) HSP 1 Score: 52.7582 bits (125), Expect = 9.018e-8 Identity = 28/80 (35.00%), Postives = 46/80 (57.50%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNK----QVV-----GRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL 860
+ RRY F+WL ++L E+ IV+PPLP K Q+ G ++++FIE RRK L+ ++ + HP+ + + FL
Sbjct: 72 VRRRYSDFEWLRNEL-ERDSKIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQNERCLHMFL 150
BLAST of Sorting nexin vs. Ensembl Fly
Match: Snx3 (gene:FBgn0038065 transcript:FBtr0082642) HSP 1 Score: 52.7582 bits (125), Expect = 9.018e-8 Identity = 28/80 (35.00%), Postives = 46/80 (57.50%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNK----QVV-----GRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL 860
+ RRY F+WL ++L E+ IV+PPLP K Q+ G ++++FIE RRK L+ ++ + HP+ + + FL
Sbjct: 72 VRRRYSDFEWLRNEL-ERDSKIVVPPLPGKAWKRQMPFRGDEGIFDESFIEERRKGLEAFINKIAGHPLAQNERCLHMFL 150
BLAST of Sorting nexin vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0309280) HSP 1 Score: 54.299 bits (129), Expect = 3.457e-7 Identity = 21/52 (40.38%), Postives = 34/52 (65.38%), Query Frame = 3
Query: 57 VIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEI 212
+Y +T + P +L I E + ++ + G+GW +ARN RGEEG +P NY++I
Sbjct: 549 ALYSYTAQNPDELTIVENEQLEVVGEGDGDGWLRARNYRGEEGYVPHNYLDI 600
BLAST of Sorting nexin vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0309277) HSP 1 Score: 54.299 bits (129), Expect = 3.462e-7 Identity = 21/52 (40.38%), Postives = 34/52 (65.38%), Query Frame = 3
Query: 57 VIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEI 212
+Y +T + P +L I E + ++ + G+GW +ARN RGEEG +P NY++I
Sbjct: 549 ALYSYTAQNPDELTIVENEQLEVVGEGDGDGWLRARNYRGEEGYVPHNYLDI 600
BLAST of Sorting nexin vs. Ensembl Zebrafish
Match: snx18a (sorting nexin 18a [Source:ZFIN;Acc:ZDB-GENE-070705-339]) HSP 1 Score: 235.343 bits (599), Expect = 8.074e-69 Identity = 137/414 (33.09%), Postives = 211/414 (50.97%), Query Frame = 3
Query: 336 SNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDK--WTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
S+ R +Q+ T S +N +F+K+GGE F+LG A K+ V++ P S CTI K +KFKGMK++I+Y+L ++T+ ++RRYK FDWL+++L EK+P I +P +P KQ GR+E++FI RR+ L W+ H+TSHPVLA +HFLS D+ W GKR+ EKD F+ + P ++ D RI+ F + + + F ++Q KE+QK+G S LS++ + D S I L + TG+ Y+ IG F +Q + D D V D L G + P +I + K A+ V+ S + E K+ + +GI +I+ AE+ + R + +S M +LQ QI + +T L EAL
Sbjct: 155 SSMPRGAQQAKSSATVSRNLNRF---STFVKSGGEAFVLGEASGFVKDGDKICVVMGQYGPEWQENPYPFS--CTIDDPTKQTKFKGMKSYISYKLTPTHTQSQVNRRYKHFDWLYARLVEKFPVISVPHIPEKQATGRFEEDFISKRRRGLIWWMNHMTSHPVLARCDVFQHFLSCSSTDEKAWKQGKRKAEKDEMVGANFFLTISTPPAPLDLQDVESRIDGFKVFSKKMDDSVIQVNATLSEFARKQIAGFKKEYQKVGQSFKYLSQAFEM--DQQSYSIGLNQAIAYTGEAYEVIGDYFVEQPKQDVDPVMDLLALYQGHLTNYPDIIHVQKGALTKVKESQKHVEEGKMESQHADGIRDRCNIISFATMAEIQYFHQTRVRDFKSQMQHFLQQQISFFQKVTGKLEEAL 561 HSP 2 Score: 55.0694 bits (131), Expect = 2.151e-7 Identity = 21/57 (36.84%), Postives = 35/57 (61.40%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+ A+ +YDF E P ++ ++ EI+ + + GW + N RG GL+PA+YVEI+
Sbjct: 3 LRARALYDFNSENPGEISVKENEIVTLYSEQDIEGWLEGTNSRGARGLLPASYVEIL 59
BLAST of Sorting nexin vs. Ensembl Zebrafish
Match: snx18a (sorting nexin 18a [Source:ZFIN;Acc:ZDB-GENE-070705-339]) HSP 1 Score: 235.343 bits (599), Expect = 8.074e-69 Identity = 137/414 (33.09%), Postives = 211/414 (50.97%), Query Frame = 3
Query: 336 SNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDK--WTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
S+ R +Q+ T S +N +F+K+GGE F+LG A K+ V++ P S CTI K +KFKGMK++I+Y+L ++T+ ++RRYK FDWL+++L EK+P I +P +P KQ GR+E++FI RR+ L W+ H+TSHPVLA +HFLS D+ W GKR+ EKD F+ + P ++ D RI+ F + + + F ++Q KE+QK+G S LS++ + D S I L + TG+ Y+ IG F +Q + D D V D L G + P +I + K A+ V+ S + E K+ + +GI +I+ AE+ + R + +S M +LQ QI + +T L EAL
Sbjct: 155 SSMPRGAQQAKSSATVSRNLNRF---STFVKSGGEAFVLGEASGFVKDGDKICVVMGQYGPEWQENPYPFS--CTIDDPTKQTKFKGMKSYISYKLTPTHTQSQVNRRYKHFDWLYARLVEKFPVISVPHIPEKQATGRFEEDFISKRRRGLIWWMNHMTSHPVLARCDVFQHFLSCSSTDEKAWKQGKRKAEKDEMVGANFFLTISTPPAPLDLQDVESRIDGFKVFSKKMDDSVIQVNATLSEFARKQIAGFKKEYQKVGQSFKYLSQAFEM--DQQSYSIGLNQAIAYTGEAYEVIGDYFVEQPKQDVDPVMDLLALYQGHLTNYPDIIHVQKGALTKVKESQKHVEEGKMESQHADGIRDRCNIISFATMAEIQYFHQTRVRDFKSQMQHFLQQQISFFQKVTGKLEEAL 561 HSP 2 Score: 55.0694 bits (131), Expect = 2.151e-7 Identity = 21/57 (36.84%), Postives = 35/57 (61.40%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+ A+ +YDF E P ++ ++ EI+ + + GW + N RG GL+PA+YVEI+
Sbjct: 3 LRARALYDFNSENPGEISVKENEIVTLYSEQDIEGWLEGTNSRGARGLLPASYVEIL 59
BLAST of Sorting nexin vs. Ensembl Zebrafish
Match: snx33 (sorting nexin 33 [Source:ZFIN;Acc:ZDB-GENE-041111-209]) HSP 1 Score: 220.32 bits (560), Expect = 2.036e-63 Identity = 124/388 (31.96%), Postives = 196/388 (50.52%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
SF+++G E F+LG + I + + + P S C+I K +KFKG+KT+I+Y++ S+T + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFL D +W GKR EKD F + P + + D RI+ +F + L V + ++ G KEFQ++G+ ++S+S L P +S +S + + TG Y+ IG++F Q ++D + D L G++ P +I L K A V+ S R S E K+ +GI + R + + AE+N RE + M YL+ QI Y + L L +
Sbjct: 165 SFVRSGVEAFILGDVPMMAKIAESYSIEMGPRGPQWMDNPRPFS--CSIEDPTKQTKFKGIKTYISYRVTPSHTGRPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFEHFLMCGDDKQWKLGKRRAEKDEMVGAHFMLTFQIPNEHQDLQDVEERIDSFKSFAKKMDDSVMQLTNVASELVRKHLGGFRKEFQRLGNGFQSISQSFLLDPPYSSDALS--NAISHTGRTYENIGEMFADQPKNDLFQMLDKLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGKMDQGEADGIRKRCRTVGFALQAEMNHFHQRREVDFKEMMQAYLRQQIAFYQRVGQQLERTLRMY 548
BLAST of Sorting nexin vs. Ensembl Zebrafish
Match: snx18b (sorting nexin 18b [Source:ZFIN;Acc:ZDB-GENE-080213-6]) HSP 1 Score: 213.772 bits (543), Expect = 6.536e-61 Identity = 127/393 (32.32%), Postives = 201/393 (51.15%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL--SVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF*HA 1589
+F+K+GGE F+LG A K+ V++ S P + CTI K +KFKGMK++++Y L S+T+ ++RRYK FDWL+++L EK+P I +P LP KQ GR+E++FI RRK L W+ H+TSHPVL+ +HFL S D+ W GKR+ EKD F+ + P ++ + ++E TF +++ + N F ++Q KE+Q++G + LS++ + D L + TG+VY+ IG F +Q + D + + D L G + P +I + K A+ + S + E T GI+ +I+ AE+ R + ++ M +LQ QI + IT L EAL + A
Sbjct: 177 TFVKSGGEAFVLGEASGLVRDGDKIFVVMGQSGPEWQENPYAFT--CTIDDPTKQTKFKGMKSYMSYGLTPSHTQSQVNRRYKHFDWLYARLVEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMTSHPVLSKCDVFQHFLTCSSTDEKAWKQGKRKAEKDDLVGANFFLTICPPALPLDLQEVENKVEGFKTFTKKMDENIIQVNVTINEFARKQITGFKKEYQRVGQAFRLLSQAFEV--DQQVFSSPLNKAMANTGEVYETIGDYFAEQPRQDLEPISDLLAIYQGHLANFPDIIHVQKGALTKAKESQKHGEEKDGTAGG--GINDRCNIISCATLAEIQHFHCIRVRDFKAQMQYFLQQQISFFQKITGKLEEALDMYDQA 563 HSP 2 Score: 63.1586 bits (152), Expect = 6.731e-10 Identity = 24/57 (42.11%), Postives = 38/57 (66.67%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+ A+ +YDFT E P ++ + E++ + ++V +GW + N RGE GL PA+YVEII
Sbjct: 3 LRARALYDFTSENPGEISVTENEVLTLCSEEVVDGWLEGTNSRGETGLFPASYVEII 59
BLAST of Sorting nexin vs. Ensembl Zebrafish
Match: snx18b (sorting nexin 18b [Source:ZFIN;Acc:ZDB-GENE-080213-6]) HSP 1 Score: 211.075 bits (536), Expect = 6.149e-60 Identity = 126/393 (32.06%), Postives = 200/393 (50.89%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL--SVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF*HA 1589
+F+K+GGE F+LG A K+ V++ S P + CTI K +KFKGMK++++Y L S+T+ ++RRYK FDWL+++L EK+P I +P LP KQ GR+E++FI RRK L W+ H+TSHPVL+ +HFL S D+ W GKR+ EKD F+ + P ++ + ++E TF +++ + N F ++Q KE+Q++G + LS++ + D L + TG+VY+ IG F +Q + D + + D L + P +I + K A+ + S + E T GI+ +I+ AE+ R + ++ M +LQ QI + IT L EAL + A
Sbjct: 177 TFVKSGGEAFVLGEASGLVRDGDKIFVVMGQSGPEWQENPYAFT--CTIDDPTKQTKFKGMKSYMSYGLTPSHTQSQVNRRYKHFDWLYARLVEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMTSHPVLSKCDVFQHFLTCSSTDEKAWKQGKRKAEKDDLVGANFFLTICPPALPLDLQEVENKVEGFKTFTKKMDENIIQVNVTINEFARKQITGFKKEYQRVGQAFRLLSQAFEV--DQQVFSSPLNKAMANTGEVYETIGDYFAEQPRQDLEPISDLLAIYQAHLANFPDIIHVQKGALTKAKESQKHGEEKDGTAGG--GINDRCNIISCATLAEIQHFHCIRVRDFKAQMQYFLQQQISFFQKITGKLEEALDMYDQA 563 HSP 2 Score: 63.1586 bits (152), Expect = 6.731e-10 Identity = 24/57 (42.11%), Postives = 38/57 (66.67%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+ A+ +YDFT E P ++ + E++ + ++V +GW + N RGE GL PA+YVEII
Sbjct: 3 LRARALYDFTSENPGEISVTENEVLTLCSEEVVDGWLEGTNSRGETGLFPASYVEII 59
BLAST of Sorting nexin vs. Ensembl Xenopus
Match: snx18 (sorting nexin 18 [Source:NCBI gene;Acc:496591]) HSP 1 Score: 221.09 bits (562), Expect = 2.890e-63 Identity = 121/387 (31.27%), Postives = 201/387 (51.94%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDE--INWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
+F+K+GGE F+LG A + + ++ V E W+ C+I K +KFKGMK++I+Y+L S+T + RRYK FDWL+++L +K+P + +P +P KQ GR+E++FI R+K L W+ H+ SHPVLA +HFLS D+ W GKR+ E+D F+ + P + +D R++ F ++ L + F ++Q+ KE+QK+G ++ L ++ + D+ L + TG+ Y+ IG++F +Q + D D + D L G + P +I + + A+ V S ++ E K+ L+ I VI+ AE++ R + +S M +LQ QI + +T L EAL
Sbjct: 198 AFVKSGGEAFVLGEA--AGFVRDGDKLCVVPGAEGPEWQENPYPFRCSIDEPTKQTKFKGMKSYISYRLLPSHTGLQVHRRYKHFDWLYARLLDKFPVVSVPRIPEKQATGRFEEDFISKRKKGLVWWMEHMCSHPVLARCDAFQHFLSCTDEKAWKQGKRKCERDEMVGANFFLTLSLPPGSPVLEPHDVDGRLDGFKVFTKRMDEGVLQLSQTAGEFARKQAAGFKKEYQKVGQAVRGLGQAFEM--DHMVFSAGLNRAMAFTGEAYEAIGEMFAEQPRQDLDPIMDLLAVYQGHLANFPDIIHVQRGALTKVRESKKQVEEGKLELQKAGEIQERCNVISYATLAEIHHFHKIRVRDFKSQMQHFLQQQICFFQKVTLKLEEAL 580 HSP 2 Score: 54.299 bits (129), Expect = 5.521e-7 Identity = 21/60 (35.00%), Postives = 35/60 (58.33%), Query Frame = 3
Query: 36 MSQIEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
M + A+ +YDF E P ++ + E++ + + GW + N RGE GL PA+YVE++
Sbjct: 1 MMALRARALYDFRAENPGEVSLRESEVLSLCSEQDIEGWLEGLNSRGERGLFPASYVEVL 60
BLAST of Sorting nexin vs. Ensembl Xenopus
Match: csrp2 (cysteine and glycine rich protein 2 [Source:Xenbase;Acc:XB-GENE-943913]) HSP 1 Score: 219.164 bits (557), Expect = 7.672e-63 Identity = 117/389 (30.08%), Postives = 203/389 (52.19%), Query Frame = 3
Query: 417 SFLKNGGEEFLLG-LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
SF+++G E F+LG + + E+ ++ + WK C++ K +KFKG+K++I+Y+L + RRYK FDWL+++L K+ I +P LP KQ GR+E++FI+ R++ L W+ H+TSHPVL+ +HFLS +D+ +W GKR E+D F ++ P + + D R++ F +++ L V + ++ G KEFQ++G+++ LS S L P +S+ L+ + TG Y+ +G++F +Q ++D D L G++ P +I L K A V+ S R S E ++ + +GI + RV+ + AE+N R + + + YL+ QI Y ++ L + L +
Sbjct: 163 SFVRSGVEAFVLGDVPQFGGVSESHA---IEMGPKGPQWKANPRPFSCSVEEPTKQTKFKGIKSYISYRLTPDPCNSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIQKRKRRLVLWMDHMTSHPVLSQYDGFQHFLSCQDEKQWKAGKRRAERDELVGASFLLTLQLPTEHQDLQDVEERVDVFKAFSKKMDENVLQLSSVVSELARKHLGGFRKEFQRLGAALQGLSHSFQLDPPYSSE--PLVGAISHTGRTYEAVGEMFAEQPKNDQFRFLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMEQDEADGIRKRCRVVGFALQAEINHFHQRRLQDFKQAIQHYLKEQILFYRRVSQELEKTLHMY 546
BLAST of Sorting nexin vs. Ensembl Xenopus
Match: snx9 (sorting nexin 9 [Source:NCBI gene;Acc:100145698]) HSP 1 Score: 213.386 bits (542), Expect = 3.085e-61 Identity = 142/510 (27.84%), Postives = 242/510 (47.45%), Query Frame = 3
Query: 57 VIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIISXXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYP-CIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
++YDF+ E + +L ++ GEI+ + ++DVG GW +A+N +G+ GL+P +YV I S P + + + N+ + + +T P +L G E G A+ A +++ ++ +W + C + K +K G+K++I YQL ++ T ++ RYK FDWL+ +L K+ I IP LP+KQV GR+E+ FI+ R + LQ W++ + HPV++ S+T + FL+ +D+ +W GKR+ EKD + VE +++ + ++ E VS F + + L V KR +GP+ KE+QKIG ++ LS+ S + L + G Y+ I L +Q + D + + G + P +I K A+ V+ S + KIT + + + V V++ + AE+N + R S + YL+ QIQ Y I L +ALS F
Sbjct: 6 ILYDFSAEPGNNELTVKEGEIVTVTNKDVGGGWIEAKNSQGDRGLVPTDYVTIKSPASPLPLFTSEGLLLTLMY------------------VFYNQMFYFLAVDDDEWDDDWDDTKSSPPGYL--GSETSETGAAQRGAGRPASMKIPLNYGP---MWVYPTSTYDCIVADPRKGTKLYGLKSYIEYQLTATNTNRSVNHRYKHFDWLYERLLIKFGLAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMSRMCRHPVISESETFQQFLNFRDEKEWKIGKRKAEKDEIVGSMIFSTVEPEAQDLDMTEVEQKCEAVSRFTRAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQTLSQVFST--SGYQGETELNSAIIEAGKTYEAIANLVEEQPKKDLHYLMETNHEYKGFLSCFPDIISAHKGALEKVKESDKLVATSKITQQDKVNMMKRVSVMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQIQFYETIAEKLKQALSQF 490
BLAST of Sorting nexin vs. Ensembl Xenopus
Match: snx9 (sorting nexin 9 [Source:NCBI gene;Acc:100145698]) HSP 1 Score: 204.142 bits (518), Expect = 6.043e-58 Identity = 140/512 (27.34%), Postives = 240/512 (46.88%), Query Frame = 3
Query: 51 AKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIISXXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYP-CIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
A+V+YDF+ E + +L ++ GEI+ + ++DVG GW +A+N +G+ GL+P + Y+++ + N+ + + +T P +L G E G A+ A +++ ++ +W + C + K +K G+K++I YQL + T ++ RYK FDWL+ +L K+ I IP LP+KQV GR+E+ FI+ R + LQ W++ + HPV++ S+T + FL+ +D+ +W GKR+ EKD + VE +++ + ++ E VS F + + L V KR +GP+ KE+QKIG ++ LS+ S + L + G Y+ I L +Q + D + + G + P +I K A+ V+ S + KIT + + + V V++ + AE+N + R S + YL+ QIQ Y I L +ALS F
Sbjct: 4 ARVLYDFSAEPGNNELTVKEGEIVTVTNKDVGGGWIEAKNSQGDRGLVPTD-------------------YVELLTLMY---------------VFYNQMFYFLAVDDDEWDDDWDDTKSSPPGYL--GSETSETGAAQRGAGRPASMKIPLNYGP---MWVYPTSTYDCIVADPRKGTKLYGLKSYIEYQLTN--TNRSVNHRYKHFDWLYERLLIKFGLAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMSRMCRHPVISESETFQQFLNFRDEKEWKIGKRKAEKDEIVGSMIFSTVEPEAQDLDMTEVEQKCEAVSRFTRAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQTLSQVFST--SGYQGETELNSAIIEAGKTYEAIANLVEEQPKKDLHYLMETNHEYKGFLSCFPDIISAHKGALEKVKESDKLVATSKITQQDKVNMMKRVSVMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQIQFYETIAEKLKQALSQF 472
BLAST of Sorting nexin vs. Ensembl Xenopus
Match: snx9 (sorting nexin 9 [Source:NCBI gene;Acc:100145698]) HSP 1 Score: 188.734 bits (478), Expect = 1.375e-51 Identity = 119/400 (29.75%), Postives = 201/400 (50.25%), Query Frame = 3
Query: 384 SSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYP-CIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
S K+ + P F K+G +++L+ AK + K+ +++ + V+ + C + K +K G+K++I YQL ++ T ++ RYK FDWL+ +L K+ I IP LP+KQV GR+E+ FI+ R + LQ W++ + HPV++ S+T + FL+ +D+ +W GKR+ EKD + VE +++ + ++ E VS F + + L V KR +GP+ KE+QKIG ++ LS+ S + L + G Y+ I L +Q + D + + G + P +I K A+ V+ S + KIT + + + V V++ + AE+N + R S + YL+ QIQ Y I L +ALS F
Sbjct: 169 SMKIPLSKFP-GFAKSGVDQYLM--AKQIPKTKEKIPIIIGDYGPMWVYP--TSTYDCIVADPRKGTKLYGLKSYIEYQLTATNTNRSVNHRYKHFDWLYERLLIKFGLAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMSRMCRHPVISESETFQQFLNFRDEKEWKIGKRKAEKDEIVGSMIFSTVEPEAQDLDMTEVEQKCEAVSRFTRAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQTLSQVFSTS--GYQGETELNSAIIEAGKTYEAIANLVEEQPKKDLHYLMETNHEYKGFLSCFPDIISAHKGALEKVKESDKLVATSKITQQDKVNMMKRVSVMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQIQFYETIAEKLKQALSQF 561 HSP 2 Score: 57.7658 bits (138), Expect = 4.485e-8 Identity = 22/44 (50.00%), Postives = 34/44 (77.27%), Query Frame = 3
Query: 87 SDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIIS 218
SDL ++ GEI+ + ++DVG GW +A+N +G+ GL+P +YVE IS
Sbjct: 2 SDLTVKEGEIVTVTNKDVGGGWIEAKNSQGDRGLVPTDYVEFIS 45
BLAST of Sorting nexin vs. Ensembl Mouse
Match: Snx18 (sorting nexin 18 [Source:MGI Symbol;Acc:MGI:2137642]) HSP 1 Score: 234.572 bits (597), Expect = 4.954e-68 Identity = 137/396 (34.60%), Postives = 203/396 (51.26%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDS------QF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL---SVKDKDKWTNGKREIEKDYHKSGRFYCAVE-APVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
+F+K+GGE F+LG A + D K V P G F CTI K +KFKGMK++I+Y+L ++T+ + RRYK FDWL+++L+EK+P I +P LP KQ GR+E++FI RRK L W+ H+ SHPVLA +HFL S D+ W GKR+ EKD F+ + P ++ + +I+ F + + L N F ++Q KE+QK+G S LS++ L D + + L + TGD YD IG+LF +Q + D D V D L G + P +I + K A+ V+ S R E K+ ++ +GI I+ AE++ R + +S M +LQ QI + +T L EAL
Sbjct: 225 TFVKSGGEAFVLGEAS---------GFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL--DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEAL 609 HSP 2 Score: 50.447 bits (119), Expect = 7.290e-6 Identity = 19/57 (33.33%), Postives = 34/57 (59.65%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+ A+ +YDF E P ++ + E++ + + GW + N RG+ GL PA+YV++I
Sbjct: 3 LRARALYDFKSENPGEISLREHEVLSLCSEQDIEGWLEGINSRGDRGLFPASYVQVI 59
BLAST of Sorting nexin vs. Ensembl Mouse
Match: Snx33 (sorting nexin 33 [Source:MGI Symbol;Acc:MGI:2443239]) HSP 1 Score: 223.787 bits (569), Expect = 2.235e-64 Identity = 125/393 (31.81%), Postives = 198/393 (50.38%), Query Frame = 3
Query: 420 FLKNGGEEFLLG----LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF*H 1586
F+++G E F+LG +AK++ T ++ WK C+I K +KFKG+K++I+Y+L ++ + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFLS D +W GKR EKD F + P + + D R++ F + L V ++ G KEFQK+GS+ +S + + P S +L + + TG Y+ +G++F +Q + D + D L G++ P +I L K A V+ S R S E ++ E +GI R RV+ + AE+N RE + M YL+ QI Y + L + L + H
Sbjct: 189 FVRSGVEAFILGDVPMMAKIAETYS------IEMGPRGPQWKANPHPFACSIEDPTKQTKFKGIKSYISYKLTPTHAGSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSNVAAELVRKHVGGFRKEFQKLGSAFQAISHAFQMDPPFRSD--ALNNAISHTGRTYETVGEMFAEQPKHDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMAQEEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQSYLRQQILFYQRVGQQLEKTLHMYDH 573 HSP 2 Score: 53.9138 bits (128), Expect = 5.738e-7 Identity = 22/57 (38.60%), Postives = 36/57 (63.16%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
++ + +YDF E ++ I+ E +VI + +GW + +N RGE GL PA+YVEI+
Sbjct: 3 LKGRALYDFHSENKEEISIQQDEELVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
BLAST of Sorting nexin vs. Ensembl Mouse
Match: Snx9 (sorting nexin 9 [Source:MGI Symbol;Acc:MGI:1913866]) HSP 1 Score: 184.496 bits (467), Expect = 5.946e-50 Identity = 120/407 (29.48%), Postives = 201/407 (49.39%), Query Frame = 3
Query: 366 SQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKY-PCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
S+ S K+ + P F K G E++LL AK + K+ ++V + V+ S F C + K SK G+K++I YQL + T ++ RYK FDWL+ +L K+ I IP LP+KQV GR+E+ FI+ R + LQ W+T + HPV++ S+ + FL+ +D+ +W GKR+ EKD + +E +++ + ++ + V F + + L V KR +GP+ KE+QKIG ++ +L+ S D++ + G Y+ I L +Q + D + + G + P +I K A+ V+ S + KIT + + + + V ++ + AE+N + R S + YL+ Q+Q Y I L +ALS F
Sbjct: 194 SRAGASSMKLPLNKFP-GFAKPGMEQYLL--AKQLAKPKEKIAIIVGDYGPMWVYP---TSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVVSESEVFQQFLNFRDEKEWKTGKRKAEKDELVGVMIFSTMEPEAPDLDLIEIEQKCDAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLAAVFSSSGYQGETDLN--DAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGAHKGAIEKVKESDKLVATSKITPQDKQTMVKRVGTMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRF 592 HSP 2 Score: 60.4622 bits (145), Expect = 4.858e-9 Identity = 25/57 (43.86%), Postives = 41/57 (71.93%), Query Frame = 3
Query: 48 EAKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+A+V+YDF E + +L + GEII + + +VG GW + +N +GE+GL+P +YVEI+
Sbjct: 4 KARVMYDFAAEPGNNELTVTEGEIITVTNPNVGGGWLEGKNNKGEQGLVPTDYVEIL 60
BLAST of Sorting nexin vs. Ensembl Mouse
Match: Snx30 (sorting nexin family member 30 [Source:MGI Symbol;Acc:MGI:2443882]) HSP 1 Score: 88.9669 bits (219), Expect = 2.571e-18 Identity = 87/354 (24.58%), Postives = 147/354 (41.53%), Query Frame = 3
Query: 540 GDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKD-------GISRRYKQFDWLHSQLSEKYPCIVIPPLPNK----QVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNG-----KREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNN-----FHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLY 1538
G+++ + D M+T+ITY++ + T+ + RRY+ FDWL ++L E P +IPPLP K VV R+ + F+E RRK L K+L +T HPVL++++ FL+ KD + + R E H +G Y P++ +DY + TF RI Q + R+ GP+ + + + +S C N S + L T D+ + + R+ L D+++ + +V A E AV + RK K+ + + DR + + A++ Q+ + R +V IQ Y
Sbjct: 86 GEARDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLSRVGESVKHVTGG-YKLRSRPLEFAAISDY------LDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEEL-----TDDITEEFLPVLREYV-----LYSDSMKGVLKKRDQVQAEYEAKLEAV-----ALRKEERPKVPADVEKCQDR-MECFNADLKADMERWQSNKRHDFRQLLVGLADKNIQYY 416
BLAST of Sorting nexin vs. Ensembl Mouse
Match: Snx7 (sorting nexin 7 [Source:MGI Symbol;Acc:MGI:1923811]) HSP 1 Score: 82.8037 bits (203), Expect = 2.163e-16 Identity = 61/201 (30.35%), Postives = 106/201 (52.74%), Query Frame = 3
Query: 552 FCTIIAHDKSSKFKGMKTFITYQLQSSYTKDG-------ISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVG----RYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEA--------PVDEINWNDYSRRIEKVSTFIDNFEKHS-RILQEVYNNFHK-RQSGPI 1091
F T+ A + S ++TFITY++ + ++ + RRY+ F WL +L E +P ++IPPLP K +V R+ D+FIE RRK L K+L + HP L +++ K FL+ + ++ ++ K++ + G+ AV + P + + N++ IE S I+ +K S RI +E + F + ++ GPI
Sbjct: 83 FITVDAPE--SHVTTIETFITYRIVTKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKVFLTAQ-AEELSSYKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNF---IETFSQKINLIDKISQRIYKEERDYFDEMKEYGPI 277
BLAST of Sorting nexin vs. UniProt/SwissProt
Match: sp|Q8I4E2|LST4_CAEEL (Sorting nexin lst-4 OS=Caenorhabditis elegans OX=6239 GN=lst-4 PE=1 SV=1) HSP 1 Score: 239.195 bits (609), Expect = 2.180e-69 Identity = 136/395 (34.43%), Postives = 216/395 (54.68%), Query Frame = 3
Query: 384 SSKVN-TIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYT--KDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTIL 1559
S+KVN I +F+K+G E +++G +K ++ I + EV+++N WKP+ C + K SK KG+K+FI Y + SS T + +SRRYK FDWLH QLS KY I IPPLP KQV GRYE++ I+ R+ LQ W+ + HPVL+ S+ HF+S D+ W NGKR EKD + G F + P ++ N+ ++E+ + E+ R++QE N F K +GP+ + +QK+GS+ L +S + D L L T Y IG++F ++D + V +NL + G ++ VP +I++ K AV + +E +++ E + + + ++ TV AE+ E+ + ++STM YL+ Q Y + T L
Sbjct: 173 SNKVNKNINRFSNFVKSGVEAYVIGESKTTSQISERHEVVMNNG--IIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQRQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQRSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEI--DETVASRRLTEALAYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKF-----RDSEGRLSSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 558
BLAST of Sorting nexin vs. UniProt/SwissProt
Match: sp|Q91ZR2|SNX18_MOUSE (Sorting nexin-18 OS=Mus musculus OX=10090 GN=Snx18 PE=1 SV=1) HSP 1 Score: 225.328 bits (573), Expect = 8.083e-64 Identity = 122/343 (35.57%), Postives = 183/343 (53.35%), Query Frame = 3
Query: 555 CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL---SVKDKDKWTNGKREIEKDYHKSGRFYCAVE-APVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
CTI K +KFKGMK++I+Y+L ++T+ + RRYK FDWL+++L+EK+P I +P LP KQ GR+E++FI RRK L W+ H+ SHPVLA +HFL S D+ W GKR+ EKD F+ + P ++ + +I+ F + + L N F ++Q KE+QK+G S LS++ L D + + L + TGD YD IG+LF +Q + D D V D L G + P +I + K A+ V+ S R E K+ ++ +GI I+ AE++ R + +S M +LQ QI + +T L EAL
Sbjct: 268 CTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL--DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEAL 608
BLAST of Sorting nexin vs. UniProt/SwissProt
Match: sp|Q4VAA7|SNX33_MOUSE (Sorting nexin-33 OS=Mus musculus OX=10090 GN=Snx33 PE=1 SV=1) HSP 1 Score: 223.787 bits (569), Expect = 1.563e-63 Identity = 125/393 (31.81%), Postives = 198/393 (50.38%), Query Frame = 3
Query: 420 FLKNGGEEFLLG----LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF*H 1586
F+++G E F+LG +AK++ T ++ WK C+I K +KFKG+K++I+Y+L ++ + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFLS D +W GKR EKD F + P + + D R++ F + L V ++ G KEFQK+GS+ +S + + P S +L + + TG Y+ +G++F +Q + D + D L G++ P +I L K A V+ S R S E ++ E +GI R RV+ + AE+N RE + M YL+ QI Y + L + L + H
Sbjct: 189 FVRSGVEAFILGDVPMMAKIAETYS------IEMGPRGPQWKANPHPFACSIEDPTKQTKFKGIKSYISYKLTPTHAGSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSNVAAELVRKHVGGFRKEFQKLGSAFQAISHAFQMDPPFRSD--ALNNAISHTGRTYETVGEMFAEQPKHDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMAQEEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQSYLRQQILFYQRVGQQLEKTLHMYDH 573 HSP 2 Score: 53.9138 bits (128), Expect = 4.013e-6 Identity = 22/57 (38.60%), Postives = 36/57 (63.16%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
++ + +YDF E ++ I+ E +VI + +GW + +N RGE GL PA+YVEI+
Sbjct: 3 LKGRALYDFHSENKEEISIQQDEELVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
BLAST of Sorting nexin vs. UniProt/SwissProt
Match: sp|Q8WV41|SNX33_HUMAN (Sorting nexin-33 OS=Homo sapiens OX=9606 GN=SNX33 PE=1 SV=1) HSP 1 Score: 222.631 bits (566), Expect = 4.054e-63 Identity = 124/391 (31.71%), Postives = 199/391 (50.90%), Query Frame = 3
Query: 420 FLKNGGEEFLLG----LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
F+++G E F+LG +AK++ T ++ WK C++ K +KFKG+K++I+Y+L ++ + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFLS D +W GKR EKD F + P + + D R++ F + L V + ++ G KEFQK+GS+ +S S + P S+ +L + TG Y+ IG++F +Q ++D + D L G++ P +I L K A V+ S R S E ++ + +GI R RV+ + AE+N RE + M YL+ QI Y + L + L +
Sbjct: 189 FVRSGVEAFILGDVPMMAKIAETYS------IEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSE--ALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMY 571 HSP 2 Score: 53.9138 bits (128), Expect = 3.682e-6 Identity = 22/57 (38.60%), Postives = 36/57 (63.16%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
++ + +YDF E ++ I+ E +VI + +GW + +N RGE GL PA+YVEI+
Sbjct: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
BLAST of Sorting nexin vs. UniProt/SwissProt
Match: sp|Q28GP7|SNX33_XENTR (Sorting nexin-33 OS=Xenopus tropicalis OX=8364 GN=snx33 PE=2 SV=1) HSP 1 Score: 219.164 bits (557), Expect = 4.064e-62 Identity = 117/389 (30.08%), Postives = 203/389 (52.19%), Query Frame = 3
Query: 417 SFLKNGGEEFLLG-LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
SF+++G E F+LG + + E+ ++ + WK C++ K +KFKG+K++I+Y+L + RRYK FDWL+++L K+ I +P LP KQ GR+E++FI+ R++ L W+ H+TSHPVL+ +HFLS +D+ +W GKR E+D F ++ P + + D R++ F +++ L V + ++ G KEFQ++G+++ LS S L P +S+ L+ + TG Y+ +G++F +Q ++D D L G++ P +I L K A V+ S R S E ++ + +GI + RV+ + AE+N R + + + YL+ QI Y ++ L + L +
Sbjct: 163 SFVRSGVEAFVLGDVPQFGGVSESHA---IEMGPKGPQWKANPRPFSCSVEEPTKQTKFKGIKSYISYRLTPDPCNSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIQKRKRRLVLWMDHMTSHPVLSQYDGFQHFLSCQDEKQWKAGKRRAERDELVGASFLLTLQLPTEHQDLQDVEERVDVFKAFSKKMDENVLQLSSVVSELARKHLGGFRKEFQRLGAALQGLSHSFQLDPPYSSE--PLVGAISHTGRTYEAVGEMFAEQPKNDQFRFLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMEQDEADGIRKRCRVVGFALQAEINHFHQRRLQDFKQAIQHYLKEQILFYRRVSQELEKTLHMY 546
BLAST of Sorting nexin vs. TrEMBL
Match: A0A4E0R7W2 (Sorting nexin 9 variant OS=Fasciola hepatica OX=6192 GN=D915_005884 PE=4 SV=1) HSP 1 Score: 297.36 bits (760), Expect = 2.979e-89 Identity = 181/543 (33.33%), Postives = 286/543 (52.67%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII---SXXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNK-ERF--------------SQRT---------SQIVTESSKVNTIR--MPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEA--PVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
+ A+VIYDF+ + +L + +GE + I DQ VG+GWW ARN G EGLIP+++VE + P PPP+ Y D +D D D + + S + N +RF S RT + I T+S ++ +R P+SFL++GG++FLL + + E +++ VW+PL C I + K SK KG+K+FI YQL +S TK +SRRYK FDWL+ +L KYPC+ IPPLP K + GRYED F++ RRK LQ WL + HPV+A S HFL+ D +W GKRE E D + GRFY V++ P +++N E F E+ ++IL + ++H++ SG K++ ++ ++ F L RS+ ++++L+ L G+ Y I +++ A + ++ D L + + P+++ L KCA + + + R + E K++ I VITR+V AE NW+ + + + +YL+ Q + + I L++A S F
Sbjct: 1 MRARVIYDFSAQAEGELSVAAGEEVTITDQSVGSGWWGARNDFGREGLIPSSFVEPLDIPEPNIPPPPPPQMMNYGDASAVQDWDDDWDSDESDHGSMVQPNATDRFLGPSTRKQSENTSCSSRTFGQVPGSGPTPIHTDSMRLVPLRKGFPRSFLRSGGDDFLLNNDPPTL---PQTEAIIEFVNGIFVWRPLDTPIQCKISSFHKDSKMKGIKSFIAYQLNTSLTKAHVSRRYKHFDWLYCRLVAKYPCVRIPPLPEKAITGRYEDEFVDERRKLLQLWLDRMCKHPVVAQSHVFIHFLTCADVKRWKPGKREAETDRCQGGRFYFDVDSKDPPCALDYNLAC--AEAAEKFAIEMERDTKILCDTLCDYHRKLSGAHAKDYSELSTACFRLCRSLETDVHTKDRNVTLIRALTGAGEAYKAI-RIYHAAACEPTVVLLDCLRDFSRLFNGFPSVMCLGKCACISSDEADRLAAEGKLSHTDATSIRTGSLVITRSVQAECNWIMEQLRAEYLTKFAEYLREQARFHRQIADQLDQAASLF 537
BLAST of Sorting nexin vs. TrEMBL
Match: A0A075AC92 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_00616 PE=4 SV=1) HSP 1 Score: 282.722 bits (722), Expect = 2.159e-83 Identity = 176/537 (32.77%), Postives = 264/537 (49.16%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIISXXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQI---------------VTESSKVNTIRMP-------KSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAV--EAPVDEINWNDYSRR-IEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
+ +V++DF + +L I +GE + I DQ VG+GWW A N G+ GL+P +VE I PEP PPP PP I E+++ D + + +R S++ +T S ++R +SF+K+G EEFLL L S EA +E E W+P G S C I++ K SK KGMK+FI YQL S + ++RRYK FDWLH++L K+PCI IP LP+K + GRYED+F+E RRK LQ+WL + HPV++ KHFLS D +W GKRE E D+ + RF+ A+ E PV DYS I+ + E+ R+ E FH+R + K+F + S+ + R+++ + ++++ L TGD + + Q++ L+E E + +PA++ L K A VE + R E K++ E I VI R+V AE W+ + + + YL ++ L A S+F
Sbjct: 38 VRVRVLFDFAAQGVGELSITTGEQLTITDQTVGDGWWSAVNSSGQRGLVPCAFVEPIDPPEPNVPPPPPPANIQQTEWDEEWDSDDSNSTVPTTYRSGKPNDAVRRCSELNQPGSPVKSQFISTGITGSPAGESVRFAPVRKAFTRSFIKSGAEEFLLQLETPSVHTEAVIEF----RDEAFCWRPSGQSIQCKILSFHKDSKMKGMKSFIAYQLTSPFVSSHVNRRYKHFDWLHARLVSKFPCICIPSLPDKAITGRYEDDFLEERRKQLQQWLDRMCRHPVVSQCSVFKHFLSCTDAKRWKQGKREAETDHLQGARFFFAINSEEPVTPA---DYSLEIIDSAEKLAADLERGVRVFAEALVEFHRRMTTSTSKDFLAVSSAFLGVCRAINCDIYDKNRNMPLFAAFSNTGDAFRSLSVYHAVQSEPTTQLLECVREHAR-TLATLPAVVSLGKSACVAVEEARRLLAEGKLSQHDAESIQSGAVVIVRSVQAECVWIMQQLRQDFLERVKDYLLDRAAFCRQYADQLQSAASFF 566
BLAST of Sorting nexin vs. TrEMBL
Match: C1LG69 (Sorting nexin-18 OS=Schistosoma japonicum OX=6182 PE=2 SV=1) HSP 1 Score: 281.567 bits (719), Expect = 2.451e-83 Identity = 180/533 (33.77%), Postives = 287/533 (53.85%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIISXXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQIV---TESS----------KVNTIR--MPKSFLKNGGEEFLLGLAKLS-TTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKST-----ECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
++ +VIYDF+ + +L + GE + I +Q+VG+GWW+A N G+EGLIP+ +VEII PEPT PPP P + + D + ++ D++ +D A+ + + R+ Q+V T+SS + IR P+SF++NGGE+FLLG EA ++++ D T W+ + I + K SK KG+K+FI YQ+ +S + +SRRYK FDWLHS+L KYPC+ IPPLP K + GRYED+F++ RRK LQ+WLT + HPV+++S HFL+ D KW GKRE E D + GRFY AVE + + + E F+ + ++ ++ L E N +H++ S I KEF + + N+S+++ + L L TG + + + Q++ +L ++ L+ ++ +I LAK A TV+ +R S E K + V I +ITR+V AE N + ++ + + + YL Q + Y I ++ ++ F
Sbjct: 1 MKVRVIYDFSAQWSGELSVSIGEELTITNQNVGSGWWQAVNAFGKEGLIPSEFVEIIELPEPTAPPPSLPP-TEFGKEIDRFDEWDDEWDSDENDTATLNKNLNDRSQQVVSKQTDSSISVPNNPDYIRTTLIRKFFPRSFIRNGGEDFLLGHDPPPFPQTEANIDLIDD----TFRWRYVSSDLTSCISSFRKDSKMKGIKSFIAYQITNSLSHTQVSRRYKHFDWLHSRLLSKYPCVCIPPLPEKAITGRYEDDFVDERRKWLQQWLTRMCMHPVISHSSVFLHFLTCTDFKKWKLGKREAETDKLQGGRFYFAVETKSGHTSQDYTVEKAEAAERFLSDLDRSTKFLSETVNEYHRKLSTSIRKEFSTLSLAFLNMSKAIESDVHTKPLNTKLCESLTATGTTFRTVACIHSLQSEASINL-QECLKEFTRLLPSTSNIISLAKAACLTVDELNRVSNNNSADEQKYSQSDVNRIQSGALIITRSVQAECNHIMSQIRNEWMNKIKDYLNEQARFYHQIAELIEKSAQSF 527
BLAST of Sorting nexin vs. TrEMBL
Match: A0A4Z2D6X6 (Sorting nexin-33 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_004003 PE=4 SV=1) HSP 1 Score: 281.182 bits (718), Expect = 3.739e-83 Identity = 180/533 (33.77%), Postives = 286/533 (53.66%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIISXXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQIV---TESS----------KVNTIR--MPKSFLKNGGEEFLLGLAKLS-TTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKST-----ECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
++ +VIYDF+ + +L + GE + I +Q+VG+GWW+A N G+EGLIP+ +VEII PEPT PPP P + + D + ++ D++ +D A+ + + R+ Q+V T+SS + IR P+SF++NGGE+FLLG EA ++++ D T W+ + I + K SK KG+K+FI YQ+ +S + +SRRYK FDWLHS+L KYPC+ IPPLP K + GRYED+F++ RRK LQ+WLT + HPV+++S HFL+ D KW GKRE E D + GRFY AVE + + + E F+ + ++ ++ L E N +H++ S I KEF + + N+S+++ + L L TG + + + Q++ +L ++ L+ ++ +I LAK A TV+ +R S E K V I +ITR+V AE N + ++ + + + YL Q + Y I ++ ++ F
Sbjct: 1 MKVRVIYDFSAQWSGELSVSIGEELTITNQNVGSGWWQAVNAFGKEGLIPSEFVEIIELPEPTAPPPSLPP-TEFGKEIDRFDEWDDEWDSDENDTATLNKNLNDRSQQVVSKQTDSSISVPNNPDYIRTTLIRKFFPRSFIRNGGEDFLLGHDPPPFPQTEANIDLIDD----TFRWRYVSSDLTSCISSFRKDSKMKGIKSFIAYQITNSLSHTQVSRRYKHFDWLHSRLLSKYPCVCIPPLPEKAITGRYEDDFVDERRKWLQQWLTRMCMHPVISHSSVFLHFLTCTDFKKWKLGKREAETDKLQGGRFYFAVETKSGHTSQDYTVEKAEAAERFLSDLDRSTKFLSETVNEYHRKLSTSIRKEFSTLSLAFLNMSKAIESDVHTKPLNTKLCESLTATGTTFRTVACIHSLQSEASINL-QECLKEFTRLLPSTSNIISLAKAACLTVDELNRVSNNNSADEQKYCQSDVNRIQSGALIITRSVQAECNHIMSQIRNEWMNKIKDYLNEQARFYHQIAELIEKSAQSF 527
BLAST of Sorting nexin vs. TrEMBL
Match: A0A4Y2JWP3 (Sorting nexin lst-4 OS=Araneus ventricosus OX=182803 GN=lst-4_3 PE=4 SV=1) HSP 1 Score: 280.026 bits (715), Expect = 1.187e-82 Identity = 169/533 (31.71%), Postives = 273/533 (51.22%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIISX--------------XXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQIVTESSKVNTIRMPKSF------LKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
+ + +YDF + S +L I + EI+ + +QDVG GWW+ N RG++GL PA YVE S + T +D + D DWDD + + SN + R S+ + + + + KSF +K+GGE ++LG K+S E + ++ N + W C++ + +K +K KG+K+FI YQL S+ +SRRYK FDWLH +L EK+ I IPPLP+KQ+ GRYE +FI+ R+ LQ W+ + HPVL+ S+ HFL+ D +W +GKR EKD G F+ A+ P + + ++I+ + F+ + + L V + HKR +GP+ KE Q++ S +L + + +S SL ++ T VY+ +GK++ +Q + D + + D L G++ P ++ + K A+N V + + + +++ + V I + VI+ +E+N ER +S M YL QI Y ITT L E L+YF
Sbjct: 5 FQVRALYDFDAQPGSGELSIAANEILTVTNQDVGEGWWEGVNSRGQKGLFPAGYVEAASSAPPPAMPPPPPPADAQITAFSESVLPGVDAVDDWDDDWDDDDSEPGAVQTQVSNASLVTTRESRDLQRAVESRGT-LKKSFNRFSTFVKSGGEGYILGETKISVPTEQCITIIETNGE--IQWLESTSPYTCSVDSPNKKTKLKGLKSFIAYQLIPSFNNIAVSRRYKHFDWLHERLEEKFTLIPIPPLPDKQISGRYEKDFIDHRKNQLQMWVNRICRHPVLSQSEVWMHFLTCTDDKRWKSGKRNAEKDKLIGGSFFHAISTPSIPLENANVEKQIDLFNRFVMKMDDSVKQLFNVAVDQHKRYAGPVKKEIQRMSESFNDLGTAFGMYSSEHSD--SLTTAIKYTASVYEELGKMYEEQPKYDAEPMADVLHEYKGMLSAWPDVLHIQKSALNKVAEHKKLAEDGRLSQDDVAAISQRTDVISYATLSEINHFHNERVAYFKSMMETYLTAQIDFYQRITTKLQETLAYF 532
BLAST of Sorting nexin vs. Ensembl Cavefish
Match: snx18a (sorting nexin 18 [Source:NCBI gene;Acc:103026104]) HSP 1 Score: 231.876 bits (590), Expect = 1.793e-67 Identity = 130/387 (33.59%), Postives = 200/387 (51.68%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL--SVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
+F+K+GGE F+LG A K+ V++ P S CTI K +KFKGMK++I+Y+L ++T+ ++RRYK FDWL+++L EK+P I +P +P KQ GR+E++FI RRK L W+ H+TSHPVLA +HFL S D+ W GKR+ EKD F+ + P ++ + +I+ F + + N F ++Q KE+QK+G S LS++ L D + L + TG+ Y+ IG F +Q + D D V D L G + P +I + K A+ V+ S + E K+ + +GI+ +I+ AE+ R + ++ M YLQ QI + +T L EAL
Sbjct: 199 TFVKSGGEAFVLGEASGFVKDGDKICVVMGQYGPEWQENPYPFS--CTIDDPTKQTKFKGMKSYISYKLTPTHTQSQVNRRYKHFDWLYARLVEKFPVISVPHIPEKQATGRFEEDFISKRRKGLIWWMNHMTSHPVLARCDVFQHFLTCSSTDEKAWKQGKRKAEKDEMVGANFFLTISTPAAPLDLQEVESKIDGFKAFTKKMDDSVIQVNATLNEFARKQIAGFKKEYQKVGQSFKYLSQAFEL--DQQAYSTGLNQAIAYTGEAYEAIGDYFAEQPKQDVDPVMDLLALYQGHLANYPDIIHVQKGALTKVKESQKHVEEGKMERQQADGINERCNIISFATLAEIQHFHHIRVRDYKAQMQHYLQQQISFFQKVTGKLEEAL 581 HSP 2 Score: 60.4622 bits (145), Expect = 3.528e-9 Identity = 24/56 (42.86%), Postives = 38/56 (67.86%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEI 212
++A+V+YDFT E P ++ ++ EI+ + + GW + N RGE GL+PA+YVEI
Sbjct: 3 LQARVLYDFTSENPGEISVKENEIVTLYSEQDIEGWLEGTNSRGERGLLPASYVEI 58
BLAST of Sorting nexin vs. Ensembl Cavefish
Match: snx33 (sorting nexin 33 [Source:NCBI gene;Acc:103035633]) HSP 1 Score: 220.32 bits (560), Expect = 1.541e-63 Identity = 123/388 (31.70%), Postives = 197/388 (50.77%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
SF+++G E F+LG + I + + WK C++ K +KFKG+KT+I+Y++ S+T + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFL D +W GKR EKD F + P + + D RI+ +F + L V + ++ G KEFQ++G+S ++S++ L P +S +L + + TG Y+ IG++F +Q + D + D L G++ P +I L K A V+ S R S E K+ + +GI + R + + AE+N RE + M YL+ QI Y + L L +
Sbjct: 165 SFVRSGVEAFVLGDVPMMAKIAEAYSI--EMGPRGPQWKESPQPFCCSVEDPTKQTKFKGIKTYISYRVTPSHTGRPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFEHFLMCGDDKQWKLGKRRAEKDEMVGAHFMLTLHIPNEHQDLQDVEERIDTFKSFAKKMDDSVLQLTHVASELVRKHLGGFRKEFQRLGNSFQSISQAFMLDPPYSSD--ALNNAISHTGRTYENIGEMFAEQPKFDLFHMLDKLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGKMDQDEADGIRKRCRTVGFALQAEMNHFHQRREVDFKEMMQAYLRQQIAFYQRVGQQLERTLHMY 548 HSP 2 Score: 55.4546 bits (132), Expect = 1.520e-7 Identity = 23/57 (40.35%), Postives = 36/57 (63.16%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
++AK +Y F E ++ I+ E ++I +++ +GW + N RGE GL PA YVEII
Sbjct: 3 LKAKALYTFQSENKEEISIQENEELLIFEENSVDGWLRGENSRGERGLFPATYVEII 59
BLAST of Sorting nexin vs. Ensembl Cavefish
Match: snx18b (sorting nexin-18-like [Source:NCBI gene;Acc:103036978]) HSP 1 Score: 213.386 bits (542), Expect = 8.661e-61 Identity = 130/425 (30.59%), Postives = 210/425 (49.41%), Query Frame = 3
Query: 321 ASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL--SVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF*HA 1589
+S+ +++ R S + T + N R +F+K+GGE F+LG A E K+ V++ P+ + CTI K +KFKGMK++++Y L S+T+ ++RRYK FDWL+++L E++P I +P LP KQ GR+E++FI RRK L W+ H+T+HPVL+ +HFL S D+ W GKR+ E+D F+ + PV ++ + +++ F +++ + F ++Q KE+Q++G + L ++ L D + L + T Y+ IG F +Q + D + V D L G + P +I + K A+ + S R S E + GI +I+ AE+ R + ++ M YLQ QI Y IT L E L F A
Sbjct: 153 SSNFSASPRRGSSQQQSRSTATVGRNLNRF-STFVKSGGEAFVLGEASGFVREEDKICVVMGQFGPEWQQNPVPFT--CTIDDPTKQTKFKGMKSYMSYGLTPSHTQSQVNRRYKHFDWLYARLVERFPVISVPHLPEKQATGRFEEDFITKRRKGLVWWMNHMTTHPVLSRCDVFQHFLTCSSTDEKAWKQGKRKAERDCLVGANFFLTIVPPVAPLDLQEVESKVDGFKAFAKKMDENLTQVNVTLGEFARKQVTGFRKEYQRVGQAFQLLGQAFEL--DQQEYSVKLNQAIGFTSQAYEAIGDYFAEQPRQDLEPVSDLLAIYQGHLANFPDIIHVQKGALTKTKESQRHSEE----KDGPAGIHERCNIISCATLAEMQHFHRTRVRDFKAQMQHYLQQQIIFYQRITGKLEETLHMFDQA 568 HSP 2 Score: 60.8474 bits (146), Expect = 2.730e-9 Identity = 23/58 (39.66%), Postives = 38/58 (65.52%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIIS 218
+ A+ +YDF E P ++ + E++ + ++V +GW + N RGE GL PA+YVEI+S
Sbjct: 3 LRARALYDFVSENPGEISVVESELLTLYSEEVVDGWLEGTNSRGESGLFPASYVEILS 60
BLAST of Sorting nexin vs. Ensembl Cavefish
Match: snx9a (sorting nexin-9-like [Source:NCBI gene;Acc:103023149]) HSP 1 Score: 185.652 bits (470), Expect = 4.014e-51 Identity = 109/353 (30.88%), Postives = 182/353 (51.56%), Query Frame = 3
Query: 546 SQFCTIIAHDK-SSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPC-IVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIG------SSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
+Q ++AH K +K G+K++I YQ+ + T ++ RYK FDWL+ +L EK+ C I IP LP+KQV GR+ED FI+ R + LQ W++ + HPV++ S+ + FL+ KD+ W GKR+ EKD + ++ + E++ + ++ E S F + + + L V + KR +GP+ KE+Q+IG SS+FN S + +L L TG Y+ I ++ Q + D + + G++ P LI + + A+ V+ + R KI + + + +N+ ++ + AE+N + R M YLQ Q+Q Y I L ALS +
Sbjct: 171 TQLDCVVAHPKKGTKMYGLKSYIEYQIAPNTTHKSVNHRYKHFDWLYERLLEKFGCAIPIPSLPDKQVTGRFEDEFIKMRMERLQGWMSRMCRHPVVSNSEVFQLFLTYKDEKDWKEGKRKAEKDERVGVMVFSTMDPEMRELDPTEVEKKCETFSHFSRSMDDGVKDLLAVGHLHWKRCAGPLQKEYQRIGKAFQSLSSVFNTSAYQG--------EATLTDALTATGKTYEEIAEIVAGQPKKDLHFLLETNNEYKGLLGCFPDLIGVHRAAIEKVKEADRLVAMNKIGPQDKQTMQKNLSTMSYALQAEMNHFHSNRIYDYNRVMQLYLQEQVQFYETIAGKLKHALSQY 515 HSP 2 Score: 59.3066 bits (142), Expect = 8.644e-9 Identity = 23/59 (38.98%), Postives = 45/59 (76.27%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIIS 218
++A+V+YDFT E + +L ++ GE++ +++Q VG GW +A+N +G+ GL+P +Y++ I+
Sbjct: 3 VKAQVLYDFTAEPGNNELSVQEGEMLTVMNQAVGGGWVEAQNSKGQTGLVPEDYIQQIN 61
BLAST of Sorting nexin vs. Ensembl Cavefish
Match: snx9b (sorting nexin-9 [Source:NCBI gene;Acc:103024560]) HSP 1 Score: 177.178 bits (448), Expect = 1.056e-47 Identity = 104/344 (30.23%), Postives = 172/344 (50.00%), Query Frame = 3
Query: 555 CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKY-PCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEA-PVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
C + K SK G+K++I YQ+ + T ++ RYK FDWL+ +L EK+ I IP LP+KQV GR+E+ FI+ R + LQ W+T + HPV++ S+ + FL+ KD+ W GKR+ EKD + +E V ++ ++ ++ E+ S F + + L V N KR +GP+ KE+Q+IG + NLS + + +L L G Y+ I ++ +Q + D + + G++ P I + K A+ V+ + + KIT + + ++ + AE+N + R M QYL+ Q++ Y I L A S F
Sbjct: 208 CVVADPKKGSKMYGLKSYIEYQVTPNTTNKPVNHRYKHFDWLYERLLEKFGSAIPIPCLPDKQVTGRFEEEFIKMRMERLQGWMTRMCRHPVVSSSEVFQLFLTYKDEKDWKTGKRKAEKDETVGVMIFSTIEPEGVPDLEIHEVEQKCEQFSRFTKAMDDGVKDLLTVGNEHWKRCTGPLPKEYQRIGKAFQNLSSVFT--SSGYEGEATLTDALTAAGKTYEEIAQMVAEQPRKDLHFLMETNNEYKGLLGCFPDTIGVHKAAIEKVKEADKLVAASKITSAEKVTMGKRASSMSYALQAEMNHFHSNRIYDYNRVMQQYLEEQVKFYETIAEKLRHAHSQF 549 HSP 2 Score: 61.6178 bits (148), Expect = 1.432e-9 Identity = 27/55 (49.09%), Postives = 40/55 (72.73%), Query Frame = 3
Query: 51 AKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEI 212
A+V+YDF+ E + +L + GE I I +Q++G GW +ARN RGE GL+P +YVE+
Sbjct: 5 AQVLYDFSAEPGNNELSVREGETITITNQNIGGGWIEARNSRGEVGLVPEDYVEL 59
BLAST of Sorting nexin vs. Ensembl Sea Lamprey
Match: snx18b (sorting nexin 18b [Source:ZFIN;Acc:ZDB-GENE-080213-6]) HSP 1 Score: 209.149 bits (531), Expect = 4.645e-60 Identity = 124/388 (31.96%), Postives = 190/388 (48.97%), Query Frame = 3
Query: 420 FLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQF---CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEA-PVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
++K GGE F+ G T+ V VD + W D+ F C+I K +KFKGMK+FI+Y+L ++T +SRRYK FDWL+ +L +K+P + +P LP KQ GR+ ++F++ RR+ L W+ H+T HPVLA +HFL+ D+ W GKR EKD +FY + A P ++ D R + +F ++ +L ++ ++FQK+G NL +S D+ +L + TG+ Y IG+LF +Q Q D + D G++ P +I + K AV V+ S R + E K+ + + ++ AE N R K M YLQ QI Y I L+E+L
Sbjct: 161 YVKAGGEAFISGDVT-GCTVNVGDRVRVDIADRGPAWP---DNPFPFTCSIEDPTKQTKFKGMKSFISYRLTPTFTGRAVSRRYKHFDWLYGRLVQKFPVVSVPHLPEKQATGRFVEDFVQKRRRGLILWMNHMTGHPVLAQCDAFQHFLTCTDEKAWKQGKRRAEKDDAVGAKFYLTISAPPTSHLDLQDVEARTDSFRSFSKRMDESVVLLNGTAGEMARKHCIDYKRDFQKMGQVFENLGQSFE--QDDQHYSDNLTKAITHTGNTYVAIGELFAQQPQQDLQPLMDVTCLYQGLLANFPDIIHIQKGAVAKVKESQRAADEGKMDAGQLTEVQTRTNTVSHATLAEFNHFHCTRVKDFGQIMQLYLQQQIAFYQAIAGRLDESL 542 HSP 2 Score: 58.5362 bits (140), Expect = 3.297e-9 Identity = 22/60 (36.67%), Postives = 36/60 (60.00%), Query Frame = 3
Query: 36 MSQIEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
M A+ +YDF E ++ I +++ + ++ VG+GW++ N RGE GL PA YVE +
Sbjct: 1 MVSRRARALYDFQSENEGEISIRERDVLTVFNEGVGDGWFEGTNSRGERGLFPATYVEFL 60
BLAST of Sorting nexin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001438.1 (pep scaffold:Pmarinus_7.0:GL485280:2234:11313:-1 gene:ENSPMAG00000001299.1 transcript:ENSPMAT00000001438.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.76 bits (260), Expect = 1.049e-24 Identity = 53/144 (36.81%), Postives = 74/144 (51.39%), Query Frame = 3
Query: 555 CTIIAHDKSSKFKGMKTFITYQLQSSYTKDG----------ISRRYKQFDWLHSQLSEKYPCIVIPPLPNK-QVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDK-DKWTNGKREIEKDYHKSGRFYCAVE 950
C + A K SKF G+K+++ Y+L +S + RRYKQF WL ++L EK+P +V+P LP RY + R L WL HVT HP LA ++HFL+ D ++W GKR E+D FY V+
Sbjct: 12 CAVSAPSKRSKFGGIKSYLAYELTTSSAAAAAAADSPAPSPVWRRYKQFAWLRARLEEKFPAVVVPRLPGTLPAAARYAPECVRRRVGELSLWLEHVTGHPALAGCDVLRHFLTCGDNVEEWKGGKRRAERDRDVGHSFYLGVD 155
BLAST of Sorting nexin vs. Ensembl Sea Lamprey
Match: snx30 (sorting nexin family member 30 [Source:NCBI gene;Acc:550496]) HSP 1 Score: 81.6481 bits (200), Expect = 7.226e-17 Identity = 41/104 (39.42%), Postives = 62/104 (59.62%), Query Frame = 3
Query: 594 GMKTFITYQLQSSYTK---DG----ISRRYKQFDWLHSQLSEKYPCIVIPPLPN----KQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKD 872
M+T+ITY++ T+ DG + RRY+ FDWL ++L E P +IPPLP K VV R+ ++F+ R+K L K+L + +HP L++S FL+ KD
Sbjct: 39 AMETYITYRVTVRTTRSEYDGMEFVVRRRYQDFDWLRTKLEETQPTHIIPPLPEKFVMKGVVDRFTEDFVTTRQKALDKFLNRLANHPTLSFSSYFHSFLTAKD 142
BLAST of Sorting nexin vs. Ensembl Sea Lamprey
Match: snx3 (sorting nexin 3 [Source:ZFIN;Acc:ZDB-GENE-030131-921]) HSP 1 Score: 53.1434 bits (126), Expect = 4.887e-9 Identity = 30/93 (32.26%), Postives = 49/93 (52.69%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVV---------GRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDK-WTNGK 896
+ RRY F+WL ++L E+ IV+PPLP K G ++D+FI RR L++++ + HP+ + + FL + DK + GK
Sbjct: 14 VRRRYSDFEWLKNEL-ERDSKIVVPPLPGKAFTRLLPFRGDDGIFDDSFIAERRSGLEQFINKIAGHPLAQNERCLHMFLQDETIDKGYVPGK 105
BLAST of Sorting nexin vs. Ensembl Sea Lamprey
Match: snx1a (sorting nexin 1a [Source:ZFIN;Acc:ZDB-GENE-060302-3]) HSP 1 Score: 52.373 bits (124), Expect = 2.357e-7 Identity = 55/243 (22.63%), Postives = 101/243 (41.56%), Query Frame = 3
Query: 594 GMKTFITYQLQSSYT-------KDGISRRYKQFDWLHSQLSEKYP--CIVIPPLPNKQVVGRYE-----DN-----FIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEIN-----WNDYSRRIEKVSTFIDNFEKHSRILQEVYNNF-----HKRQSGPICKEFQKIGSSIFN------LSRSMSLCPDNNSKDISLLHGLQRTGDVY 1217
GM ++ Y + ++ + + + RR+ F L+ +L+EK+ ++PP P K V+G + D+ F+E RR L+++L + HP L + FL + + N + +G +A D +N N+ E+ +N E L++++ NF H+++ F K + + N LSR++S + K I LH Q D+Y
Sbjct: 182 GMNAYMAYNVTTTTSLPMFKRKEFTVKRRFSDFLGLYEKLTEKFSHSGFIVPPAPEKSVLGMTKVKVGKDDPSSVEFVERRRAALERYLQRTSKHPTLMQDPDFRDFLERDELPRAVNTQA-----LSGAGILRMVTKA-ADAVNKMTIKMNESDSWFEEKQLEFENLETQ---LRKLHGNFEGLVNHRKEMSLNTAAFAKSAAMLGNSEDNTALSRALSQLAEVEEK-IDALHQEQANADLY 414
BLAST of Sorting nexin vs. Ensembl Yeast
Match: VPS5 (Nexin-1 homolog; required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to late Golgi; structural component of retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes; VPS5 has a paralog, YKR078W, that arose from the whole genome duplication [Source:SGD;Acc:S000005595]) HSP 1 Score: 67.3958 bits (163), Expect = 3.422e-12 Identity = 31/75 (41.33%), Postives = 43/75 (57.33%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKD 872
+SRRY+ F WL+ QL + VIPP P KQ VG +++NFIE RR ++ L + PVL + FL+ D
Sbjct: 317 VSRRYRDFRWLYRQLQNNHWGKVIPPPPEKQSVGSFKENFIENRRFQMESMLKKICQDPVLQKDKDFLLFLTSDD 391
BLAST of Sorting nexin vs. Ensembl Yeast
Match: YSC84 (Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]) HSP 1 Score: 53.5286 bits (127), Expect = 6.788e-8 Identity = 24/55 (43.64%), Postives = 34/55 (61.82%), Query Frame = 3
Query: 51 AKVIYDFTPEQPSDLHIESGEIIVIIDQ-DVGNGWWKARNRRGEEGLIPANYVEI 212
A +Y+F EQP DL + G++I I+ + D N WW R G+EG+ PANYV +
Sbjct: 414 AVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTN-GKEGIFPANYVRV 467
BLAST of Sorting nexin vs. Ensembl Yeast
Match: SNX4 (Sorting nexin; involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p [Source:SGD;Acc:S000003573]) HSP 1 Score: 51.9878 bits (123), Expect = 1.792e-7 Identity = 43/175 (24.57%), Postives = 84/175 (48.00%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVV-----GRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEIN------WNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHK--RQSGPICKEFQKIGSSIFNL 1133
+ RRY LH L ++P +IPPLP+K+V R+ F + R LQ +L V+ HP L+ S+ K FL KD W + ++ ++ +++ DE+ + ++ E+ + + +K R + ++ FHK +++ + +++ K+GS++ L
Sbjct: 75 VHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKD---WESHRKVLQD----------SLQPNKDEVTDAFMNAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQEL 236
BLAST of Sorting nexin vs. Ensembl Yeast
Match: PEX13 (Peroxisomal importomer complex component; integral peroxisomal membrane protein required for docking and translocation of peroxisomal matrix proteins; interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p; forms a complex with Pex14p and Pex17p; human homolog PEX13 complements yeast null mutant [Source:SGD;Acc:S000004181]) HSP 1 Score: 50.447 bits (119), Expect = 4.196e-7 Identity = 23/60 (38.33%), Postives = 36/60 (60.00%), Query Frame = 3
Query: 51 AKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNG----WWKARNRRGEEGLIPANYVEII 215
A+ +YDF PE P ++ ++ G+++ I+ + G WWK R + G G IP NY+EII
Sbjct: 311 ARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEII 370
BLAST of Sorting nexin vs. Ensembl Yeast
Match: MVP1 (Protein required for sorting proteins to the vacuole; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004606]) HSP 1 Score: 50.8322 bits (120), Expect = 4.605e-7 Identity = 29/92 (31.52%), Postives = 47/92 (51.09%), Query Frame = 3
Query: 597 MKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDN-FIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVK 869
+K I S + + RRY F WL L ++YP +IP LP K++ + D F++ RR L +++ V HP L+ + FL+V+
Sbjct: 152 VKHLIALPSTSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGSQNADQLFLKKRRIGLSRFINLVMKHPKLSNDDLVLTFLTVR 243
BLAST of Sorting nexin vs. Ensembl Nematostella
Match: EDO49827 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REN9]) HSP 1 Score: 244.588 bits (623), Expect = 2.771e-73 Identity = 165/537 (30.73%), Postives = 273/537 (50.84%), Query Frame = 3
Query: 36 MSQIEAKVIYDFTPEQPSDLHIESGEIIVIIDQ-------DVGNGWWKARNRRGEEGLIPANYVEIIS-------------XXXXXXXXXXXXXYIDMXXXXXXXXXXXXXXXXXASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAK--LSTTIEAKVEVLVDNSK--ETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDK-WTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQS-------GPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNIT 1550
M+ + +V+YDF D +GE+IV +D+ DVG GWW+ + G +GL P YVE+IS P PP Y D ++F+D DD+ + AS +R +S T + + + R F+K+GGE ++LG A+ L E V V+ + + + VW+P C++ +K SKFKGMK+FI+Y + + T +SRR+K FDWL+++L +KY I IPPLP+KQ+ GR+ ++F+E RR+ L+KW+ + HPVL+ S + HFL+ D +K W GKR+ E D G F+ AVE P +++ + + + IDNF K R +++ N R + G E++KIG + LS+S ++ D +L ++ TG YD IG++F +Q + D + D L+ +G++ + P ++++ K + V+ + + K+ + V+ + IT AE+N R + M +LQ QI + ++
Sbjct: 1 MAGQKVRVLYDF------DGDTATGELIVSVDEVLTVTRTDVGEGWWEGITQSGIKGLFPEAYVEVISEPVAPPMPTVPIQTPSAPYQPPPSNDYYDAEDFDDDWDDDTGSSYSGGDPQASTMQRRDTGSSIHRTGTVRKSMNRF-SVFVKSGGEAYVLGTAEESLQVPPEETVRVITRSGEGAASIVWEPSSAPFTCSVTEPEKKSKFKGMKSFISYNVVPTNTMRPVSRRFKHFDWLYNRLVDKYTLIAIPPLPDKQITGRFGEDFVEKRREKLEKWVGRLCQHPVLSKSPVVNHFLTCADSEKEWKAGKRKAENDKFTGGAFFRAVECPPTKLS-------LYAIDSHIDNFGKFVRSMEDSVKNIVDRGTTHCEKCIGSYKTEYKKIGGTFTALSQSFAV-DDITENSQALTKAVEHTGKTYDDIGEMFAEQPRQDFLPLIDGLKEYSGMLSQYPEILQIHKGTIGKVKECIKLKEDEKMEVRIVDTVSSRADTITAVSFAEMNHFHQLRVADFKVMMQSFLQEQIAFHQRVS 522
BLAST of Sorting nexin vs. Ensembl Nematostella
Match: EDO31460 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXV9]) HSP 1 Score: 130.954 bits (328), Expect = 1.269e-33 Identity = 66/176 (37.50%), Postives = 104/176 (59.09%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDK-WTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQS-------GPICKEFQKIGSSIFNLSRSMSL 1151
+SRR+K FDWL+++L +KY I IPPLP+KQ+ GR+ ++F+E RR+ L+KW+ + HPVL+ S + HFL+ D +K W GKR+ E D G F+ AVE P +++ + + + IDNF K R +++ N R + G E++KIG + LS+S ++
Sbjct: 4 VSRRFKHFDWLYNRLVDKYTLIAIPPLPDKQITGRFGEDFVEKRREKLEKWVGRLCQHPVLSKSPVVNHFLTCADSEKEWKAGKRKAENDKFTGGAFFRAVECPPTKLS-------LYAIDSHIDNFGKFVRSMEDSVKNIVDRGTTHCEKCIGSYKTEYKKIGGTFTGLSQSFAV 172
BLAST of Sorting nexin vs. Ensembl Nematostella
Match: EDO40294 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7T4]) HSP 1 Score: 66.2402 bits (160), Expect = 9.860e-12 Identity = 35/115 (30.43%), Postives = 59/115 (51.30%), Query Frame = 3
Query: 510 SKETCVWKPLGDSQFCTIIAH----DKSSKFKGMKT-FITYQLQSSYTKD-------GISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTS 818
S C W S+ H D + K M+ + Y++++ + D + RRY +F WL +L+E++P IPPLP K+V+GR++ FI+ R++ L+ WL + S
Sbjct: 11 SDSACFWSKPTPSRDAPCDMHVTVRDPRTHVKDMRAQYTDYKIETEGSSDIMPLGACTVRRRYSEFTWLRKKLAEEFPNASIPPLPGKRVLGRFDTEFIKNRQQGLEHWLRSLLS 125
BLAST of Sorting nexin vs. Ensembl Nematostella
Match: EDO46895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNQ3]) HSP 1 Score: 64.3142 bits (155), Expect = 4.931e-11 Identity = 28/86 (32.56%), Postives = 47/86 (54.65%), Query Frame = 3
Query: 624 QSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQV----VGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVK 869
Q + + + RRY+ F WL ++ E YP +IPPLP K R+ F++ R L K++T + HPV++++ + FL+ K
Sbjct: 54 QFDHPEYSVRRRYQDFLWLRQRMQESYPTHIIPPLPEKHSFTKHFDRFSPEFLKARELALNKFMTRIADHPVMSFNDHLHVFLTAK 139
BLAST of Sorting nexin vs. Ensembl Nematostella
Match: EDO31495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXR2]) HSP 1 Score: 60.8474 bits (146), Expect = 9.383e-10 Identity = 28/77 (36.36%), Postives = 47/77 (61.04%), Query Frame = 3
Query: 648 ISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKD 878
+SRRY F H L ++P ++P LP K+++G ++ FIE RR+ L+++LT V HP+L + + F ++K D
Sbjct: 220 VSRRYNDFVAFHDLLISRFPYRMVPKLPPKKLMGANKE-FIEARRRALKRFLTLVARHPILCNDKIVVLFFTIKGSD 295
BLAST of Sorting nexin vs. Ensembl Medaka
Match: SNX18 (sorting nexin 18 [Source:NCBI gene;Acc:101166878]) HSP 1 Score: 238.424 bits (607), Expect = 5.131e-70 Identity = 132/387 (34.11%), Postives = 203/387 (52.45%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDK--WTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
+F+K+GGE F+LG A K+ V++ N P S C I K +KFKGMK++I+Y+L ++T++ ++RRYK FDWL+++L EK+P I +P +P KQ GR+E++FI RRK L W+ H+TSHPVLA +HFL+ D+ W GKR+ EKD F+ + P +++ + +++ TF + + L + F ++Q KE+QK+G S LS++ + D + L H + TGD Y+ IG+ F +Q D D + D L G M P +I + K A+ V+ S + E K+ EGI +I+ AE+ R + ++ M YLQ QI + IT L EAL
Sbjct: 179 TFVKSGGEAFVLGEAAGFVKDGDKICVVMGNYGPEWQENPYPFS--CAIDDPTKQTKFKGMKSYISYKLTPTHTQNPVNRRYKHFDWLYARLVEKFPVISVPHIPEKQATGRFEEDFISKRRKGLIWWMNHMTSHPVLARCDVFQHFLTCNSADEKAWKQGKRKAEKDDMVGANFFLTISPPAVPLDFQEVESKVDGFKTFSKRMDDSALQLHATVSEFARKQISGFRKEYQKVGMSFKFLSQAFEM--DQQAYSSGLNHAISFTGDTYEAIGEYFSEQPSKDLDPIMDLLALYQGHMANYPDIIHVQKGALTKVKESQKHVEEGKMDRAQAEGISDRCNIISYATLAEIQHFHQIRVRDFKTQMQHYLQQQIAFFQKITGKLEEAL 561 HSP 2 Score: 58.9214 bits (141), Expect = 9.754e-9 Identity = 24/57 (42.11%), Postives = 37/57 (64.91%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
+ A+V+YDFT E P +L ++ E++ + + GW + N RGE GL PA+YVEI+
Sbjct: 3 LRARVLYDFTSENPGELSVKESELLTLHSEQDIEGWLEGANGRGERGLFPASYVEIL 59
BLAST of Sorting nexin vs. Ensembl Medaka
Match: snx33 (sorting nexin 33 [Source:NCBI gene;Acc:101171161]) HSP 1 Score: 221.09 bits (562), Expect = 1.227e-63 Identity = 124/392 (31.63%), Postives = 203/392 (51.79%), Query Frame = 3
Query: 417 SFLKNGGEEFLLG----LAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
SF+++G E F+LG +AK++ + ++ L WK + C+I K +KFKG+KT+I+Y++ S+T + RRYK FDWL+++L K+ I +P LP KQ GR+E++FIE R++ L W+ H+TSHPVL+ + +HFL D +W GKR EKD F ++ P + + D R++ TF + L V + ++ G KEFQ++G++ ++S++ L P + S ++ + + TG Y+ IG+LF +Q + D + D L G++ P +I L K A V+ S R S E K+ +GI + R + + AE++ RE + M YL+ QI Y + L L +
Sbjct: 171 SFVRSGVEAFVLGDVPMMAKIAESYTIEMGPLGPK------WKENPNPFICSIEDPTKQTKFKGIKTYISYRVTPSHTGRPVYRRYKHFDWLYNRLLNKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMNHMTSHPVLSQYEGFEHFLMCADDKQWKLGKRRAEKDEMVGAHFMLTLQIPNEHQDLQDVEERVDNFKTFAKKMDDSVMQLTNVASELVRKHLGGFRKEFQRLGNAFQSISQAFMLDPPHRSDGLN--NAISHTGRTYENIGELFAEQPKYDLFQMLDKLSLYQGLLANFPDIIHLQKGAFAKVKESQRMSDEGKMDQGEADGIRKRCRTVGFALQAEMSHFHERREVDFKDMMQAYLKEQIAFYQRVVQQLERTLRMY 554 HSP 2 Score: 50.447 bits (119), Expect = 5.473e-6 Identity = 20/57 (35.09%), Postives = 33/57 (57.89%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEII 215
++A +Y F E ++ I+ E + I D++ +GW+ N RGE GL P YVE++
Sbjct: 3 VKAVALYTFLSENKEEISIQENEELTIFDENSLDGWYLGENSRGERGLFPKTYVEVV 59
BLAST of Sorting nexin vs. Ensembl Medaka
Match: snx18b (sorting nexin-18 [Source:NCBI gene;Acc:101159837]) HSP 1 Score: 217.238 bits (552), Expect = 2.782e-62 Identity = 121/386 (31.35%), Postives = 196/386 (50.78%), Query Frame = 3
Query: 417 SFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSV-KDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEAL 1571
+F+K+GGE FLLG A K+ V+V K W+ CTI + +KFKGMK++++Y L ++T ++RRYK FDWL+ +L E++P I +P LP KQ GR+E++F+ RRK L W+ H+TSHPVLA+ +HFL+ D+ W GKR+ EKD F+ + P ++ + +I+ F +++ ++ N F ++Q+ KE+ K+G S LS++ L D + L + TG+ Y++IG F +Q D D + D L+ G + P ++ + K A+ V+ ++ G+ +I+ AE+ R + RS M +L+ QI + IT L AL
Sbjct: 168 TFVKSGGEAFLLGEASAFVKDGDKICVVV--GKYGPEWQEDPYPFTCTIDDPTRQTKFKGMKSYMSYGLTPTHTNTQVNRRYKHFDWLYGRLVERFPVISVPHLPEKQATGRFEEDFLSKRRKGLMWWMNHMTSHPVLAHCNVFQHFLTCSPDEKAWKMGKRKAEKDDLVGANFFLTISPPAVPLDLQEVENKIDNFKMFTKKLDENIVVMNATINEFARKQTTGFQKEYHKVGQSFKLLSQAFEL--DQQIFSLGLNRAIAYTGEAYEKIGDYFAEQPHQDLDHISDLLDLYRGHLANFPDILHVQKGALTKVKECPKQEG----------GLQERCNIISCATMAEIQHFHRTRVRDFRSQMQHHLRQQISFFQKITAKLENAL 539
BLAST of Sorting nexin vs. Ensembl Medaka
Match: snx9b (sorting nexin 9 [Source:NCBI gene;Acc:101165023]) HSP 1 Score: 184.111 bits (466), Expect = 3.078e-50 Identity = 115/401 (28.68%), Postives = 199/401 (49.63%), Query Frame = 3
Query: 384 SSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQF-CTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKY-PCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
S K++ + P F K+G E FLL K + + K+ + + + ++Q C + K SK G+K++I YQ+ + T ++ RYK FDWL+ +L +K+ I IP LP+KQV GR+E+ FI+ R + LQ W+T + HPV++ S+ + FLS KD+ W GKR+ EKD + +EA +++ + ++ E+ S F + + + V N KR +GP+ KE+Q+IG + NLS + + +L + G Y+ I ++ +Q + D + + G++ P I + K A++ V+ + + KIT + + + ++ + AE+N + R M QYL+ Q++ Y I L A S F
Sbjct: 160 SMKISLNKFP-GFSKSGPELFLL--CKQAAKGKEKISIYLGEVGPVWFYP---EAQLDCIVADPKKGSKMYGLKSYIEYQITPNTTNRPVNHRYKHFDWLYERLLDKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQGWMTRMCRHPVVSSSEVFQLFLSYKDEKDWKMGKRKAEKDETVGVMIFTTIEAEAPDLDLAEVEQKCEQFSRFTKAMDDGVKEILTVGNEHWKRCTGPLPKEYQRIGKAFQNLSSVFT--SSGYQGEATLTDAMTAAGKTYEEIAQIVAEQPKKDLHFLMETNNEYKGLLGCFPDTIGVHKAAIDKVKEADKLVNTNKITAQDKVTMAKRASTMSYALQAEMNHFHSNRIYDYNRVMQQYLEEQVKFYETIAAKLRHAHSQF 552 HSP 2 Score: 53.9138 bits (128), Expect = 4.280e-7 Identity = 22/54 (40.74%), Postives = 38/54 (70.37%), Query Frame = 3
Query: 60 IYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVEIIS 218
+YDFT E + +L ++ GE I + + ++G GW +A+N RGE GL+P +Y+E ++
Sbjct: 1 LYDFTAEPGNVELTVKEGETITVTNANIGGGWIEAQNSRGETGLVPEDYIEHLT 54
BLAST of Sorting nexin vs. Ensembl Medaka
Match: snx9b (sorting nexin 9 [Source:NCBI gene;Acc:101165023]) HSP 1 Score: 183.726 bits (465), Expect = 8.574e-50 Identity = 116/400 (29.00%), Postives = 198/400 (49.50%), Query Frame = 3
Query: 384 SSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKY-PCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
S K++ + P F K+G E FLL K + + K+ + + + VW C + K SK G+K++I YQ+ + T ++ RYK FDWL+ +L +K+ I IP LP+KQV GR+E+ FI+ R + LQ W+T + HPV++ S+ + FLS KD+ W GKR+ EKD + +EA +++ + ++ E+ S F + + + V N KR +GP+ KE+Q+IG + NLS + + +L + G Y+ I ++ +Q + D + + G++ P I + K A++ V+ + + KIT + + + ++ + AE+N + R M QYL+ Q++ Y I L A S F
Sbjct: 202 SMKISLNKFP-GFSKSGPELFLL--CKQAAKGKEKISIYL--GEVGPVWFYPEAQLDCIVADPKKGSKMYGLKSYIEYQITPNTTNRPVNHRYKHFDWLYERLLDKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQGWMTRMCRHPVVSSSEVFQLFLSYKDEKDWKMGKRKAEKDETVGVMIFTTIEAEAPDLDLAEVEQKCEQFSRFTKAMDDGVKEILTVGNEHWKRCTGPLPKEYQRIGKAFQNLSSVFTSS--GYQGEATLTDAMTAAGKTYEEIAQIVAEQPKKDLHFLMETNNEYKGLLGCFPDTIGVHKAAIDKVKEADKLVNTNKITAQDKVTMAKRASTMSYALQAEMNHFHSNRIYDYNRVMQQYLEEQVKFYETIAAKLRHAHSQF 594 HSP 2 Score: 57.7658 bits (138), Expect = 2.676e-8 Identity = 24/56 (42.86%), Postives = 40/56 (71.43%), Query Frame = 3
Query: 45 IEAKVIYDFTPEQPS-DLHIESGEIIVIIDQDVGNGWWKARNRRGEEGLIPANYVE 209
+A+V+YDFT E + +L ++ GE I + + ++G GW +A+N RGE GL+P +Y+E
Sbjct: 3 FKAQVLYDFTAEPGNVELTVKEGETITVTNANIGGGWIEAQNSRGETGLVPEDYIE 58
BLAST of Sorting nexin vs. Planmine SMEST
Match: SMESG000005937.1 (SMESG000005937.1) HSP 1 Score: 875.544 bits (2261), Expect = 0.000e+0 Identity = 420/420 (100.00%), Postives = 420/420 (100.00%), Query Frame = 3
Query: 321 ASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
ASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF
Sbjct: 19 ASDMASNKERFSQRTSQIVTESSKVNTIRMPKSFLKNGGEEFLLGLAKLSTTIEAKVEVLVDNSKETCVWKPLGDSQFCTIIAHDKSSKFKGMKTFITYQLQSSYTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 438
BLAST of Sorting nexin vs. Planmine SMEST
Match: SMESG000005938.1 (SMESG000005938.1) HSP 1 Score: 288.115 bits (736), Expect = 3.234e-92 Identity = 140/308 (45.45%), Postives = 203/308 (65.91%), Query Frame = 3
Query: 657 RYKQFDWLHSQLSEKYPCIVIPPLPNKQVVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSVKDKDKWTNGKREIEKDYHKSGRFYCAVEAPVDEINWNDYSRRIEKVSTFIDNFEKHSRILQEVYNNFHKRQSGPICKEFQKIGSSIFNLSRSMSLCPDNNSKDISLLHGLQRTGDVYDRIGKLFRKQAQDDGDLVEDNLEAINGVMKEVPALIELAKCAVNTVETSSRKSTECKITLETVEGIDRNVRVITRTVDAELNWLQTEREKQLRSTMVQYLQNQIQLYTNITTILNEALSYF 1580
RY QFDWL++Q +EKYPCIV+PPLP +QV GR++ FIE R+ LQ WL H+T HPVL+ S +K F S DK KW K +++ D K+G FY AV+AP D ++ S + KV+ FID++ K+S L + + FHK Q+ + KE+ KI +++ S++ PD N L GL + G+ Y IG LF QA+ D VE NL +NG+ KE+P+++EL+ A+NT+ + S+E K+ ET++ +DR V+++TRTVDAEL+WLQ R+ Q+RS M Q+L+NQI+L+T IT IL++ L F
Sbjct: 3 RYNQFDWLYNQFAEKYPCIVVPPLPGRQVAGRFKSEFIESRKVLLQHWLNHITEHPVLSNSYAIKMFFSESDKKKWKIAKLKVKNDVFKNGGFYNAVKAPTDILDIPKISEHLNKVALFIDDYYKNSCCLSDGFRRFHKYQNEGMLKEYSKISKRFLDITESLAKNPDQNQDGQDLTQGLNKIGNAYQEIGVLFESQAKIDSSFVEPNLGEMNGITKEIPSILELSNGALNTLNSCINMSSESKLDEETIKNVDRGVQLVTRTVDAELSWLQNRRQHQMRSVMCQHLKNQIELFTQITAILSDTLKNF 310
BLAST of Sorting nexin vs. Planmine SMEST
Match: SMESG000075553.1 (SMESG000075553.1) HSP 1 Score: 74.7146 bits (182), Expect = 4.458e-14 Identity = 37/104 (35.58%), Postives = 62/104 (59.62%), Query Frame = 3
Query: 570 HDKSSKFKGMKTFITYQLQSS--YTKDGISRRYKQFDWLHSQLSEKYPCIVIPPLPNKQ---VVGRYEDNFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFLSV 866
+ K+S F ++TFI Y +Q++ + + RRY F WL +LS++YP ++PPLP+K + R+ FIE RR L+K+L +T H +L+ + FL++
Sbjct: 47 YKKASSF--LETFIVYTIQTTGNFRPYSVERRYNDFQWLFQRLSDRYPMAIVPPLPDKHNLTAIERFSGIFIELRRNALEKFLQRLTDHKILSLDKEFWAFLTL 148
BLAST of Sorting nexin vs. Planmine SMEST
Match: SMESG000016684.1 (SMESG000016684.1) HSP 1 Score: 55.8398 bits (133), Expect = 6.734e-8 Identity = 30/80 (37.50%), Postives = 45/80 (56.25%), Query Frame = 3
Query: 645 GISRRYKQFDWLHSQLSEKYPCIVIPPLPNK-------QVVGRYED-NFIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL 860
+ RRY +FD L + L++ YP VIPPLP+K V + D +FI+ RR+ L+ +L + SHP L + +FL
Sbjct: 82 SVLRRYSEFDSLRASLTKLYPACVIPPLPSKINSLNPWNVAHQKRDSDFIDSRRQRLEMFLNRILSHPKLKTEILIFNFL 161
BLAST of Sorting nexin vs. Planmine SMEST
Match: SMESG000016192.1 (SMESG000016192.1) HSP 1 Score: 50.447 bits (119), Expect = 3.296e-6 Identity = 32/109 (29.36%), Postives = 47/109 (43.12%), Query Frame = 3
Query: 594 GMKTFITYQLQSSYTKDG-------ISRRYKQFDWLHSQLSEKY---PCIVIPPLPNKQVVGRY------EDN----FIEGRRKHLQKWLTHVTSHPVLAYSQTMKHFL 860
GM + Y++ + + + RR+ F LH +L KY CI IPP P K G ED F+E RR L+++L + HP+L + FL
Sbjct: 76 GMAAYFIYKINTKTNRPSFLHQEITVRRRFSDFLGLHERLKLKYLFAGCI-IPPAPEKNAFGNTKLKLSKEDQTNSEFLERRRAALERYLQRIARHPLLVIDADFREFL 183 The following BLAST results are available for this feature:
BLAST of Sorting nexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Sorting nexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Sorting nexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Sorting nexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Sorting nexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30011933 ID=SMED30011933|Name=Sorting nexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1942bpback to top protein sequence of SMED30011933-orf-1 >SMED30011933-orf-1 ID=SMED30011933-orf-1|Name=SMED30011933-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=516bp MSQIEAKVIYDFTPEQPSDLHIESGEIIVIIDQDVGNGWWKARNRRGEEGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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