run domain Beclin-1-interacting and cysteine-rich domain-containing protein

Overview
Namerun domain Beclin-1-interacting and cysteine-rich domain-containing protein
Smed IDSMED30011903
Length (bp)3548
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of run domain Beclin-1-interacting and cysteine-rich domain-containing protein (SMED30011903) t-SNE clustered cells

Violin plots show distribution of expression levels for run domain Beclin-1-interacting and cysteine-rich domain-containing protein (SMED30011903) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of run domain Beclin-1-interacting and cysteine-rich domain-containing protein (SMED30011903) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for run domain Beclin-1-interacting and cysteine-rich domain-containing protein (SMED30011903) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011903

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30011903SMESG000019857.1 dd_Smed_v4_2578_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011903SMESG000019857.1 dd_Smed_v4_2578_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30011903SMESG000019857.1 dd_Smed_v4_2578_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30011903SMESG000019857.1 dd_Smed_v4_2578_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011903SMESG000019857.1 dd_Smed_v4_2578_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30011903SMESG000019857.1 dd_Smed_v4_2578_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011903SMESG000068263.1 SMESG000068262.1 Contig4035GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011903SMESG000019857.1 Contig4035GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
prepharyngeal regionSMED30011903SMESG000019857.1 dd_Smed_v6_2578_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
secretory systemSMED30011903SMESG000019857.1 dd_Smed_v6_2578_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Human
Match: RUBCN (rubicon autophagy regulator [Source:HGNC Symbol;Acc:HGNC:28991])

HSP 1 Score: 156.762 bits (395), Expect = 3.142e-38
Identity = 82/230 (35.65%), Postives = 119/230 (51.74%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  M IP+R+L  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S+ DL     G +   L         HV  C LCQA G++CE C N+ D+IFPFEL K   C  C  C H  C    K   CPRCER + R++
Sbjct:  672 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLH-LYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACF---KSGSCPRCERLQARRE 895
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Human
Match: RUBCN (rubicon autophagy regulator [Source:HGNC Symbol;Acc:HGNC:28991])

HSP 1 Score: 156.762 bits (395), Expect = 3.409e-38
Identity = 82/230 (35.65%), Postives = 119/230 (51.74%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  M IP+R+L  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S+ DL     G +   L         HV  C LCQA G++CE C N+ D+IFPFEL K   C  C  C H  C    K   CPRCER + R++
Sbjct:  679 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDL-HLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACF---KSGSCPRCERLQARRE 902
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Human
Match: RUBCN (rubicon autophagy regulator [Source:HGNC Symbol;Acc:HGNC:28991])

HSP 1 Score: 156.377 bits (394), Expect = 4.768e-38
Identity = 82/230 (35.65%), Postives = 119/230 (51.74%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  M IP+R+L  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S+ DL     G +   L         HV  C LCQA G++CE C N+ D+IFPFEL K   C  C  C H  C    K   CPRCER + R++
Sbjct:  717 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLH-LYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACF---KSGSCPRCERLQARRE 940
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Human
Match: RUBCNL (rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420])

HSP 1 Score: 140.969 bits (354), Expect = 8.170e-35
Identity = 86/252 (34.13%), Postives = 128/252 (50.79%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQEN 1973
            II  +H  L      +  Q+  C GC      E    +RLR C Y G YFC  CHS     IPARIL  WDF  + VS  ++ LL+ I  +P+F+       L +  +    V  ++ Q   +   + +CR  N  +++  ++P H L+D   +FS+ DL  I+ G +   LK  +  ++ HV+ C LCQ  G++CE C N + VIFPF+     +C+ C  C H +C  QS E  CPRC R   R++  E+
Sbjct:  198 IIFNIHPPL-KRDLVVAAQNFFCAGCGTPV--EPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDSIWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPGH-LTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHVAGCELCQGKGFICEFCQNTT-VIFPFQTATCRRCSACRACFHKQC-FQSSE--CPRCARITARRKLLES 441
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Human
Match: RUBCNL (rubicon like autophagy enhancer [Source:HGNC Symbol;Acc:HGNC:20420])

HSP 1 Score: 141.739 bits (356), Expect = 1.500e-34
Identity = 86/252 (34.13%), Postives = 128/252 (50.79%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQEN 1973
            II  +H  L      +  Q+  C GC      E    +RLR C Y G YFC  CHS     IPARIL  WDF  + VS  ++ LL+ I  +P+F+       L +  +    V  ++ Q   +   + +CR  N  +++  ++P H L+D   +FS+ DL  I+ G +   LK  +  ++ HV+ C LCQ  G++CE C N + VIFPF+     +C+ C  C H +C  QS E  CPRC R   R++  E+
Sbjct:  278 IIFNIHPPL-KRDLVVAAQNFFCAGCGTPV--EPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDSIWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPGH-LTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHVAGCELCQGKGFICEFCQNTT-VIFPFQTATCRRCSACRACFHKQC-FQSSE--CPRCARITARRKLLES 521
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Celegans
Match: Y56A3A.16 (pep chromosome:WBcel235:III:11911111:11914315:-1 gene:WBGene00013235.1 transcript:Y56A3A.16a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y56A3A.16)

HSP 1 Score: 105.916 bits (263), Expect = 3.486e-23
Identity = 76/245 (31.02%), Postives = 112/245 (45.71%), Query Frame = 3 
Query: 1263 LRIQSNKCPGCSMSFSHEKAHRRRL--RLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPC------HWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHI----KCHLQSKERP--CPRCERRKTR 1955
            L  Q  KC  C  S      + R    R C YYG +FCS+CH     ++PAR+L  W FT  PVS  A+  L  +   P+F        L    +   AV+ LR + + + GFI  C   ++ + +   L         +L +   +FS+ DLQ I +  +   L+     A EH+  C  C+    +C  C++ +D +F FE   V   +RC GC H+    KC  +   R   CP+C R KTR
Sbjct:  338 LESQQWKCAACRQSLHTHNINDREQCPRFCDYYGLFFCSLCHGGEKSILPARVLNQWSFTELPVSDRAQRFLRAVRESPVFRIRDLPGDLVKKNKALRAVVELRQKLKHMEGFIKICIDASNQVFEFGNLSTMFASIDRYLLEHDDLFSLNDLQRIYNKDLLSLLEPLAKRAREHIIHCKKCRLQAPVCVRCNDMTDRLFAFEERAV---SRCEGCGHLSHSPKCPRRDVPRDTHCPKCARLKTR 579
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Celegans
Match: Y56A3A.16 (pep chromosome:WBcel235:III:11911001:11914317:-1 gene:WBGene00013235.1 transcript:Y56A3A.16b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y56A3A.16)

HSP 1 Score: 101.293 bits (251), Expect = 1.056e-21
Identity = 76/247 (30.77%), Postives = 112/247 (45.34%), Query Frame = 3 
Query: 1263 LRIQSNKCPGCSMSFSHEKAHRRRL--RLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPC------HWLSDICPMFSIADLQLIESGTME--RNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHI----KCHLQSKERP--CPRCERRKTR 1955
            L  Q  KC  C  S      + R    R C YYG +FCS+CH     ++PAR+L  W FT  PVS  A+  L  +   P+F        L    +   AV+ LR + + + GFI  C   ++ + +   L         +L +   +FS+ DLQ I +   +    L+     A EH+  C  C+    +C  C++ +D +F FE   V   +RC GC H+    KC  +   R   CP+C R KTR
Sbjct:  338 LESQQWKCAACRQSLHTHNINDREQCPRFCDYYGLFFCSLCHGGEKSILPARVLNQWSFTELPVSDRAQRFLRAVRESPVFRIRDLPGDLVKKNKALRAVVELRQKLKHMEGFIKICIDASNQVFEFGNLSTMFASIDRYLLEHDDLFSLNDLQRIYNKFQDLLSLLEPLAKRAREHIIHCKKCRLQAPVCVRCNDMTDRLFAFEERAV---SRCEGCGHLSHSPKCPRRDVPRDTHCPKCARLKTR 581
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Celegans
Match: cup-14 (pep chromosome:WBcel235:II:13855788:13860058:-1 gene:WBGene00013093.1 transcript:Y51H1A.2e.5 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cup-14)

HSP 1 Score: 96.2857 bits (238), Expect = 5.056e-21
Identity = 61/219 (27.85%), Postives = 106/219 (48.40%), Query Frame = 3 
Query: 1332 RLRLCHYYGYYFCSVC-HSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRK---TRKQFQENP 1976
            +   C     Y+C+ C  S   + IPAR++  WD+    VS   R        + L +    +  L +         +LR + +L+  ++ +CR+      +    P  +L     ++S ADL  ++SG ++R L S +  ++ HV  C LC+  G+ CELC   ++VI+PF  +  H+C  CF   H++C   S +  CP+C RR+   TR+   ++P
Sbjct:  115 KFETCAIDSKYYCTECMKSGGKVSIPARVVMDWDWRERAVSDRGRAWYEANQEKALINIKTTNSRLYAHAPALEETRKLREKLQLVSMYLFTCRESVSEDFRRRLWPKEYLRSEIDVYSFADLIDVKSGALQRRLNSLLKHSINHVMTCTLCKQKGFCCELC-TVNEVIYPFNTESTHRCLVCFSAFHVECWRTSGD--CPKCVRRQNFETRRAQVDDP 330
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Celegans
Match: cup-14 (pep chromosome:WBcel235:II:13855788:13860079:-1 gene:WBGene00013093.1 transcript:Y51H1A.2e.4 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cup-14)

HSP 1 Score: 96.2857 bits (238), Expect = 5.056e-21
Identity = 61/219 (27.85%), Postives = 106/219 (48.40%), Query Frame = 3 
Query: 1332 RLRLCHYYGYYFCSVC-HSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRK---TRKQFQENP 1976
            +   C     Y+C+ C  S   + IPAR++  WD+    VS   R        + L +    +  L +         +LR + +L+  ++ +CR+      +    P  +L     ++S ADL  ++SG ++R L S +  ++ HV  C LC+  G+ CELC   ++VI+PF  +  H+C  CF   H++C   S +  CP+C RR+   TR+   ++P
Sbjct:  115 KFETCAIDSKYYCTECMKSGGKVSIPARVVMDWDWRERAVSDRGRAWYEANQEKALINIKTTNSRLYAHAPALEETRKLREKLQLVSMYLFTCRESVSEDFRRRLWPKEYLRSEIDVYSFADLIDVKSGALQRRLNSLLKHSINHVMTCTLCKQKGFCCELC-TVNEVIYPFNTESTHRCLVCFSAFHVECWRTSGD--CPKCVRRQNFETRRAQVDDP 330
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Celegans
Match: cup-14 (pep chromosome:WBcel235:II:13855788:13861040:-1 gene:WBGene00013093.1 transcript:Y51H1A.2e.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cup-14)

HSP 1 Score: 96.2857 bits (238), Expect = 5.056e-21
Identity = 61/219 (27.85%), Postives = 106/219 (48.40%), Query Frame = 3 
Query: 1332 RLRLCHYYGYYFCSVC-HSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRK---TRKQFQENP 1976
            +   C     Y+C+ C  S   + IPAR++  WD+    VS   R        + L +    +  L +         +LR + +L+  ++ +CR+      +    P  +L     ++S ADL  ++SG ++R L S +  ++ HV  C LC+  G+ CELC   ++VI+PF  +  H+C  CF   H++C   S +  CP+C RR+   TR+   ++P
Sbjct:  115 KFETCAIDSKYYCTECMKSGGKVSIPARVVMDWDWRERAVSDRGRAWYEANQEKALINIKTTNSRLYAHAPALEETRKLREKLQLVSMYLFTCRESVSEDFRRRLWPKEYLRSEIDVYSFADLIDVKSGALQRRLNSLLKHSINHVMTCTLCKQKGFCCELC-TVNEVIYPFNTESTHRCLVCFSAFHVECWRTSGD--CPKCVRRQNFETRRAQVDDP 330
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Fly
Match: CG12772 (gene:FBgn0030055 transcript:FBtr0331728)

HSP 1 Score: 120.168 bits (300), Expect = 3.860e-27
Identity = 79/251 (31.47%), Postives = 128/251 (51.00%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSH-----IKCHLQSKERPCPRCERRKTR 1955
            II   H S   S+  L+ Q+++C GC M  +  K  ++  R C Y G Y C+ CH N +  IPARIL  WDF  +PV   A  L+  +++ PLF     +  L    +      + RLQ + + GFI +CR           +P H   D   M+S+ D   +++ +M R++K  +  + +HV  C LC    ++CE C    ++I+P++  KV +C+RC  C H     ++   +++  PCPRC R ++R
Sbjct:  582 IIFTEHPSESRSK-VLQKQNHRCAGCGMRVA--KHLQQHFRYCTYLGKYLCTGCHRNQISAIPARILRSWDFRCYPVCSFAYRLIEQMYAFPLFHVPDLNSQLYKH-KELAKARKRRLQLQAVKGFIANCRFATREQSFFNAIPAHITQDP-DMWSMCDFVDVQNTSMNRSIKEVIALSEQHVHNCVLCTGRAFVCEHCKG-GELIYPWQ-RKVQRCDRCGACFHNGCWKVRSRCRNQNDPCPRCSRLQSR 825
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Fly
Match: CG12772 (gene:FBgn0030055 transcript:FBtr0071221)

HSP 1 Score: 120.168 bits (300), Expect = 3.860e-27
Identity = 79/251 (31.47%), Postives = 128/251 (51.00%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSH-----IKCHLQSKERPCPRCERRKTR 1955
            II   H S   S+  L+ Q+++C GC M  +  K  ++  R C Y G Y C+ CH N +  IPARIL  WDF  +PV   A  L+  +++ PLF     +  L    +      + RLQ + + GFI +CR           +P H   D   M+S+ D   +++ +M R++K  +  + +HV  C LC    ++CE C    ++I+P++  KV +C+RC  C H     ++   +++  PCPRC R ++R
Sbjct:  582 IIFTEHPSESRSK-VLQKQNHRCAGCGMRVA--KHLQQHFRYCTYLGKYLCTGCHRNQISAIPARILRSWDFRCYPVCSFAYRLIEQMYAFPLFHVPDLNSQLYKH-KELAKARKRRLQLQAVKGFIANCRFATREQSFFNAIPAHITQDP-DMWSMCDFVDVQNTSMNRSIKEVIALSEQHVHNCVLCTGRAFVCEHCKG-GELIYPWQ-RKVQRCDRCGACFHNGCWKVRSRCRNQNDPCPRCSRLQSR 825
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Fly
Match: CG11534 (gene:FBgn0046296 transcript:FBtr0075995)

HSP 1 Score: 99.3673 bits (246), Expect = 2.964e-21
Identity = 65/209 (31.10%), Postives = 108/209 (51.67%), Query Frame = 3 
Query: 1338 RLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGND--LIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRK 1958
            RLC Y G Y+C  C+ N    IPARI+  WDF+   VS  A   + +  ++PL      +  L   +    AV +LR     +  ++ +C+  ++  L+ + + +  H L+     +S++DL  +ESG +   L+       +H+  CP+C A  Y+CE+C N ++VIFPF+ D   +C++C    H  C L  K   CP+C R + R+
Sbjct:  259 RLCDYSGLYYCPRCNWNDSNFIPARIIHNWDFSPRRVSRTALQEIRLFLNKPLIRLEEDNPKLFVFVEKLCAVKKLRQNLVHMRHYLAACKIASELKLVDQQLGVRRH-LAQSNEFYSLSDLSQVESGALSEFLQGVFKAFNDHIRSCPMCLAQAYICEICSN-NEVIFPFD-DGCIKCDQCNSIFHRVC-LTRKNMICPKCIRIQERR 463
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Fly
Match: Plekhm1 (gene:FBgn0034694 transcript:FBtr0071758)

HSP 1 Score: 93.5893 bits (231), Expect = 5.557e-19
Identity = 55/208 (26.44%), Postives = 102/208 (49.04%), Query Frame = 3 
Query: 1335 LRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRK 1958
             ++C + G Y+C+ C    + +IPARI+  WDF  + VS  A   L    S P       +  +  +      +  LR++   +  ++ +C   +  + ++      +L +   ++SIADL LI+ G + + L+        HV  C LC   G++CE+C +   V++PF +    +C  C    H +C   ++++PCP+CER + R+
Sbjct:  498 FQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNPRIYFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGREYLYEHIHLYSIADLALIQRGVLCQQLQKAFKLGEAHVLKCRLCHLKGFICEICQS-PRVLYPFHISTTFRCLACGAVFHAECL--NEKQPCPKCERIRKRE 702
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Fly
Match: Tsp47F (gene:FBgn0033629 transcript:FBtr0088151)

HSP 1 Score: 68.5514 bits (166), Expect = 2.923e-12
Identity = 42/151 (27.81%), Postives = 72/151 (47.68%), Query Frame = 3 
Query: 2262 ALTGLFMIFSVALITTGILCKSLWSDYFRLLENSMAPIPFILIALGFIFLAVTVVGFLGTIMKNWIILVTYAGLLGSMVLTEVGAAITCGVFQTQMYSTVKLGLKNVI----ANQTAVMDSVQNKFGCCGINGYQDY-----NGTLPSSCC 2687
            A   LF I  + ++  G +  +  +++   +E  +   P +LI  G I   +  +G  G I ++  +L+T+A LL  + + E+   I   VF+  +   VK  L+  I    +  T   D++Q K  CCG++   D+     N TLP SCC
Sbjct:   15 AFNVLFAISGLGILIAGAVVLADVNEFNHFVEGRVLAPPIVLIVTGLIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDTMAWDNIQQKLMCCGVDSPADWRTLSANKTLPGSCC 165
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Zebrafish
Match: rubcnl (rubicon like autophagy enhancer [Source:ZFIN;Acc:ZDB-GENE-070912-256])

HSP 1 Score: 150.214 bits (378), Expect = 9.033e-40
Identity = 77/230 (33.48%), Postives = 121/230 (52.61%), Query Frame = 3 
Query: 1284 CPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQEN 1973
            C GC      E  + ++LR C Y G YFC  CH     VIP R+L  WDF  +PV   +R LL+ I  +P+F  +  +  L S  +       L+ Q   +   + +CR    ++ +  +LP H + D+  +FS+ DL  ++ G +    K+ +  +V H+  C LCQA G++CE CH + +V+FPF+ D   +C  C  C HI C    ++  CP+C R + RK+ QE+
Sbjct:   57 CAGCGTEI--EARYMKKLRYCDYLGRYFCDGCHGGLETVIPGRVLNNWDFARYPVCNFSRQLLDSIWEQPIFKLTSVAKNLYSQAKELQRFRELQEQLISIKKLLSTCRLSAGVLDEFEQLPAHLMQDL-HLFSMDDLHRVKKGQLCAVAKALLQSSVAHIDFCELCQAKGFICEFCHGK-EVLFPFQRDTCTRCQDCRACFHISCF---RDESCPKCARLQKRKKLQED 279
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Zebrafish
Match: rubcn (rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-GENE-100922-142])

HSP 1 Score: 160.614 bits (405), Expect = 1.210e-39
Identity = 86/231 (37.23%), Postives = 126/231 (54.55%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRK-SMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    E+ + +RLR C Y G YFC  CH N   VIPA+I+  WDF+   VS  +RDLL  I  +PLF+ S  +  L   ++    V  LR Q  L+   + +CR   D++ +    LP H   D+  +FS++DL  + SG++   L+  +     HV+ C LCQA G++CE C N  D+IFP+EL+K  +C  C  C H  C     +  CPRC R   R++
Sbjct:  663 QNYRCAGCGIRI--EQDYMKRLRYCEYLGRYFCQCCHENAQSVIPAKIIRKWDFSKSYVSNFSRDLLAKISGDPLFNLSDINSALYKKVKALDTVRALREQLNLMKNLLKTCRLAKDVLEEFDSLLPGHLTEDM-QLFSLSDLNAVRSGSLTPQLRHLLRLGSTHVTHCMLCQAKGFICEFCGNDKDIIFPYELNKCLRCEDCHACYHKSCFKTGTQ--CPRCLRLTERRE 888
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Zebrafish
Match: rubcn (rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-GENE-100922-142])

HSP 1 Score: 160.614 bits (405), Expect = 1.217e-39
Identity = 86/231 (37.23%), Postives = 126/231 (54.55%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRK-SMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    E+ + +RLR C Y G YFC  CH N   VIPA+I+  WDF+   VS  +RDLL  I  +PLF+ S  +  L   ++    V  LR Q  L+   + +CR   D++ +    LP H   D+  +FS++DL  + SG++   L+  +     HV+ C LCQA G++CE C N  D+IFP+EL+K  +C  C  C H  C     +  CPRC R   R++
Sbjct:  672 QNYRCAGCGIRI--EQDYMKRLRYCEYLGRYFCQCCHENAQSVIPAKIIRKWDFSKSYVSNFSRDLLAKISGDPLFNLSDINSALYKKVKALDTVRALREQLNLMKNLLKTCRLAKDVLEEFDSLLPGHLTEDM-QLFSLSDLNAVRSGSLTPQLRHLLRLGSTHVTHCMLCQAKGFICEFCGNDKDIIFPYELNKCLRCEDCHACYHKSCFKTGTQ--CPRCLRLTERRE 897
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Zebrafish
Match: rubcn (rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-GENE-100922-142])

HSP 1 Score: 160.614 bits (405), Expect = 1.424e-39
Identity = 86/231 (37.23%), Postives = 126/231 (54.55%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRK-SMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    E+ + +RLR C Y G YFC  CH N   VIPA+I+  WDF+   VS  +RDLL  I  +PLF+ S  +  L   ++    V  LR Q  L+   + +CR   D++ +    LP H   D+  +FS++DL  + SG++   L+  +     HV+ C LCQA G++CE C N  D+IFP+EL+K  +C  C  C H  C     +  CPRC R   R++
Sbjct:  688 QNYRCAGCGIRI--EQDYMKRLRYCEYLGRYFCQCCHENAQSVIPAKIIRKWDFSKSYVSNFSRDLLAKISGDPLFNLSDINSALYKKVKALDTVRALREQLNLMKNLLKTCRLAKDVLEEFDSLLPGHLTEDM-QLFSLSDLNAVRSGSLTPQLRHLLRLGSTHVTHCMLCQAKGFICEFCGNDKDIIFPYELNKCLRCEDCHACYHKSCFKTGTQ--CPRCLRLTERRE 913
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Zebrafish
Match: rubcn (rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-GENE-100922-142])

HSP 1 Score: 147.132 bits (370), Expect = 2.450e-35
Identity = 86/257 (33.46%), Postives = 126/257 (49.03%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRK-SMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSIC--------------------------PLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    E+ + +RLR C Y G YFC  CH N   VIPA+I+  WDF+   VS  +RDLL  I  +PLF+ S  +  L   ++    V  LR Q  L+   + +CR   D++ +    LP H   D+  +FS++DL  + SG++   L+  +     HV+ C                           LCQA G++CE C N  D+IFP+EL+K  +C  C  C H  C     +  CPRC R   R++
Sbjct:  672 QNYRCAGCGIRI--EQDYMKRLRYCEYLGRYFCQCCHENAQSVIPAKIIRKWDFSKSYVSNFSRDLLAKISGDPLFNLSDINSALYKKVKALDTVRALREQLNLMKNLLKTCRLAKDVLEEFDSLLPGHLTEDM-QLFSLSDLNAVRSGSLTPQLRHLLRLGSTHVTHCMVRLAATRTHTRTDIISWIIHVCSSPQLCQAKGFICEFCGNDKDIIFPYELNKCLRCEDCHACYHKSCFKTGTQ--CPRCLRLTERRE 923
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046880.1 (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:NCBI gene;Acc:100497647])

HSP 1 Score: 162.54 bits (410), Expect = 3.887e-40
Identity = 92/249 (36.95%), Postives = 135/249 (54.22%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            II  +H++    +A +  Q+ +C GC +    E  + +RLR C Y G YFC  CH N   VIP RI+  WDF+ + VS  ++DLL  I S+PLF+    +  L   ++    V  LR+Q   L     +CR    ++     +P H L++   +FS++DL  I+ G +   L+  V     HV  C LCQA G++CE C N+ DVIFPFEL+K  +C  C  C H  C  +S+E  CP+CER + R+  
Sbjct:  623 IIFNIHTA-PTKKAAVTKQNYRCAGCGIRI--ESDYIKRLRYCEYLGKYFCQCCHENAQSVIPGRIIRKWDFSKYYVSNFSKDLLTKIWSDPLFNLQDINSPLYRKVKALEQVRLLRIQLVHLKNMFKTCRLAKGILELYDIVPGH-LTEDHHLFSLSDLTSIKKGELVPRLRDLVKSGALHVEKCMLCQAKGFICEFCQNEDDVIFPFELNKCRRCEDCKACYHKYC-FRSEE--CPKCERLRARRDL 864
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046860.1 (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:NCBI gene;Acc:100497647])

HSP 1 Score: 162.54 bits (410), Expect = 5.057e-40
Identity = 92/249 (36.95%), Postives = 135/249 (54.22%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            II  +H++    +A +  Q+ +C GC +    E  + +RLR C Y G YFC  CH N   VIP RI+  WDF+ + VS  ++DLL  I S+PLF+    +  L   ++    V  LR+Q   L     +CR    ++     +P H L++   +FS++DL  I+ G +   L+  V     HV  C LCQA G++CE C N+ DVIFPFEL+K  +C  C  C H  C  +S+E  CP+CER + R+  
Sbjct:  649 IIFNIHTA-PTKKAAVTKQNYRCAGCGIRI--ESDYIKRLRYCEYLGKYFCQCCHENAQSVIPGRIIRKWDFSKYYVSNFSKDLLTKIWSDPLFNLQDINSPLYRKVKALEQVRLLRIQLVHLKNMFKTCRLAKGILELYDIVPGH-LTEDHHLFSLSDLTSIKKGELVPRLRDLVKSGALHVEKCMLCQAKGFICEFCQNEDDVIFPFELNKCRRCEDCKACYHKYC-FRSEE--CPKCERLRARRDL 890
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046840.1 (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:NCBI gene;Acc:100497647])

HSP 1 Score: 162.54 bits (410), Expect = 5.704e-40
Identity = 92/249 (36.95%), Postives = 135/249 (54.22%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            II  +H++    +A +  Q+ +C GC +    E  + +RLR C Y G YFC  CH N   VIP RI+  WDF+ + VS  ++DLL  I S+PLF+    +  L   ++    V  LR+Q   L     +CR    ++     +P H L++   +FS++DL  I+ G +   L+  V     HV  C LCQA G++CE C N+ DVIFPFEL+K  +C  C  C H  C  +S+E  CP+CER + R+  
Sbjct:  664 IIFNIHTA-PTKKAAVTKQNYRCAGCGIRI--ESDYIKRLRYCEYLGKYFCQCCHENAQSVIPGRIIRKWDFSKYYVSNFSKDLLTKIWSDPLFNLQDINSPLYRKVKALEQVRLLRIQLVHLKNMFKTCRLAKGILELYDIVPGH-LTEDHHLFSLSDLTSIKKGELVPRLRDLVKSGALHVEKCMLCQAKGFICEFCQNEDDVIFPFELNKCRRCEDCKACYHKYC-FRSEE--CPKCERLRARRDL 905
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046930.1 (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:NCBI gene;Acc:100497647])

HSP 1 Score: 162.155 bits (409), Expect = 5.998e-40
Identity = 92/249 (36.95%), Postives = 135/249 (54.22%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            II  +H++    +A +  Q+ +C GC +    E  + +RLR C Y G YFC  CH N   VIP RI+  WDF+ + VS  ++DLL  I S+PLF+    +  L   ++    V  LR+Q   L     +CR    ++     +P H L++   +FS++DL  I+ G +   L+  V     HV  C LCQA G++CE C N+ DVIFPFEL+K  +C  C  C H  C  +S+E  CP+CER + R+  
Sbjct:  620 IIFNIHTA-PTYKAAVTKQNYRCAGCGIRI--ESDYIKRLRYCEYLGKYFCQCCHENAQSVIPGRIIRKWDFSKYYVSNFSKDLLTKIWSDPLFNLQDINSPLYRKVKALEQVRLLRIQLVHLKNMFKTCRLAKGILELYDIVPGH-LTEDHHLFSLSDLTSIKKGELVPRLRDLVKSGALHVEKCMLCQAKGFICEFCQNEDDVIFPFELNKCRRCEDCKACYHKYC-FRSEE--CPKCERLRARRDL 861
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000046922.1 (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:NCBI gene;Acc:100497647])

HSP 1 Score: 162.155 bits (409), Expect = 6.625e-40
Identity = 92/249 (36.95%), Postives = 135/249 (54.22%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            II  +H++    +A +  Q+ +C GC +    E  + +RLR C Y G YFC  CH N   VIP RI+  WDF+ + VS  ++DLL  I S+PLF+    +  L   ++    V  LR+Q   L     +CR    ++     +P H L++   +FS++DL  I+ G +   L+  V     HV  C LCQA G++CE C N+ DVIFPFEL+K  +C  C  C H  C  +S+E  CP+CER + R+  
Sbjct:  649 IIFNIHTA-PTYKAAVTKQNYRCAGCGIRI--ESDYIKRLRYCEYLGKYFCQCCHENAQSVIPGRIIRKWDFSKYYVSNFSKDLLTKIWSDPLFNLQDINSPLYRKVKALEQVRLLRIQLVHLKNMFKTCRLAKGILELYDIVPGH-LTEDHHLFSLSDLTSIKKGELVPRLRDLVKSGALHVEKCMLCQAKGFICEFCQNEDDVIFPFELNKCRRCEDCKACYHKYC-FRSEE--CPKCERLRARRDL 890
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Mouse
Match: Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:MGI Symbol;Acc:MGI:1915160])

HSP 1 Score: 160.999 bits (406), Expect = 1.097e-39
Identity = 84/231 (36.36%), Postives = 122/231 (52.81%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  MV+P+RIL  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S++DL   + G +   L         HV  C LCQA G++CE C N+ DVIFPFEL K   C  C  C H  C    K   CPRCER + R++ 
Sbjct:  625 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYYVSNFSKDLLLKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDL-HLYSLSDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEEDVIFPFELHKCRTCEECKACYHKTCF---KSGRCPRCERLQARREL 849
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Mouse
Match: Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:MGI Symbol;Acc:MGI:1915160])

HSP 1 Score: 160.999 bits (406), Expect = 1.291e-39
Identity = 84/231 (36.36%), Postives = 122/231 (52.81%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  MV+P+RIL  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S++DL   + G +   L         HV  C LCQA G++CE C N+ DVIFPFEL K   C  C  C H  C    K   CPRCER + R++ 
Sbjct:  686 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYYVSNFSKDLLLKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDL-HLYSLSDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEEDVIFPFELHKCRTCEECKACYHKTCF---KSGRCPRCERLQARREL 910
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Mouse
Match: Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:MGI Symbol;Acc:MGI:1915160])

HSP 1 Score: 160.614 bits (405), Expect = 1.675e-39
Identity = 84/231 (36.36%), Postives = 122/231 (52.81%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  MV+P+RIL  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S++DL   + G +   L         HV  C LCQA G++CE C N+ DVIFPFEL K   C  C  C H  C    K   CPRCER + R++ 
Sbjct:  672 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYYVSNFSKDLLLKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDL-HLYSLSDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEEDVIFPFELHKCRTCEECKACYHKTCF---KSGRCPRCERLQARREL 896
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Mouse
Match: Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein [Source:MGI Symbol;Acc:MGI:1915160])

HSP 1 Score: 160.614 bits (405), Expect = 1.752e-39
Identity = 84/231 (36.36%), Postives = 122/231 (52.81%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  MV+P+RIL  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S++DL   + G +   L         HV  C LCQA G++CE C N+ DVIFPFEL K   C  C  C H  C    K   CPRCER + R++ 
Sbjct:  701 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYYVSNFSKDLLLKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDL-HLYSLSDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEEDVIFPFELHKCRTCEECKACYHKTCF---KSGRCPRCERLQARREL 925
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Mouse
Match: Plekhm3 (pleckstrin homology domain containing, family M, member 3 [Source:MGI Symbol;Acc:MGI:2443627])

HSP 1 Score: 129.798 bits (325), Expect = 4.633e-30
Identity = 81/237 (34.18%), Postives = 125/237 (52.74%), Query Frame = 3 
Query: 1263 LRIQSNKCPGC--SMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQ--GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            L  QS KC GC  S+  S+ KA     ++C+Y G+Y+CS CH +   +IPARI+  WD + + VS  A++ L  ++ EPL      +  L         V+RLR + + L  ++ SCR     DL R+    P  +L     ++S+ADLQ +  G +   L   +  A  HV  C LC   G++CE+C+N  ++++PFE     +C  C    H +C  + K  PCPRC RR+ +K+
Sbjct:  507 LTAQSFKCAGCQRSIGLSNGKA-----KVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRI--FPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNN-GEILYPFEDISTSRCESCGAVFHSEC--KEKSVPCPRCVRRELQKK 733
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80U62|RUBIC_MOUSE (Run domain Beclin-1-interacting and cysteine-rich domain-containing protein OS=Mus musculus OX=10090 GN=Rubcn PE=1 SV=2)

HSP 1 Score: 160.614 bits (405), Expect = 1.225e-38
Identity = 84/231 (36.36%), Postives = 122/231 (52.81%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQF 1964
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  MV+P+RIL  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S++DL   + G +   L         HV  C LCQA G++CE C N+ DVIFPFEL K   C  C  C H  C    K   CPRCER + R++ 
Sbjct:  701 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYYVSNFSKDLLLKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDL-HLYSLSDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEEDVIFPFELHKCRTCEECKACYHKTCF---KSGRCPRCERLQARREL 925
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. UniProt/SwissProt
Match: sp|Q92622|RUBIC_HUMAN (Run domain Beclin-1-interacting and cysteine-rich domain-containing protein OS=Homo sapiens OX=9606 GN=RUBCN PE=1 SV=4)

HSP 1 Score: 156.377 bits (394), Expect = 2.290e-37
Identity = 82/230 (35.65%), Postives = 119/230 (51.74%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC +    +  + +RLR C Y G YFC  CH N  M IP+R+L  WDF+ + VS  ++DLL  I ++PLF+    +  L   +++   V  LR+Q   +     +CR   +L+     +P H   D+  ++S+ DL     G +   L         HV  C LCQA G++CE C N+ D+IFPFEL K   C  C  C H  C    K   CPRCER + R++
Sbjct:  717 QNYRCAGCGIRTDPD--YIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTEDLH-LYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACF---KSGSCPRCERLQARRE 940
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. UniProt/SwissProt
Match: sp|A7E316|PACER_BOVIN (Protein associated with UVRAG as autophagy enhancer OS=Bos taurus OX=9913 GN=RUBCNL PE=2 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 6.250e-35
Identity = 89/261 (34.10%), Postives = 135/261 (51.72%), Query Frame = 3 
Query: 1194 GDQCLPTY-IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQEN 1973
            GD   P + II  +H  L      +  Q+  C GC      E    +RLR C Y G YFC  CHS +   IPARIL  WDF  + VS  ++ LL+ I  EP+F+  H S GL +  +    V  ++ Q   +   + +CR     +++  +LP H L++   +FS+ D+  ++ G +   LK  +  ++EHV+ C LCQ  G++CE C + + VIFPF+     +C+ C  C H +C   SK   CPRC R   R++  E+
Sbjct:  405 GDWAPPRFQIIFDIHPPLKRDLVVI-AQNFFCAGCGTPI--EPKFVKRLRYCEYLGKYFCDCCHSYSESCIPARILRMWDFRKYYVSNFSKRLLDHIWHEPIFNLLHVSHGLYTKAKELDRVREIQEQLFHIKKLLKTCRFAESTLKEFEQLPGH-LTEALHLFSLEDMVKVKKGLLAPLLKDILKASLEHVASCELCQGKGFICEFCRSTA-VIFPFQTATCRRCSACRACFHKQCFQSSK---CPRCARITARRRLLES 657
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9H714|PACER_HUMAN (Protein associated with UVRAG as autophagy enhancer OS=Homo sapiens OX=9606 GN=RUBCNL PE=1 SV=3)

HSP 1 Score: 141.739 bits (356), Expect = 2.897e-33
Identity = 86/252 (34.13%), Postives = 128/252 (50.79%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQEN 1973
            II  +H  L      +  Q+  C GC      E    +RLR C Y G YFC  CHS     IPARIL  WDF  + VS  ++ LL+ I  +P+F+       L +  +    V  ++ Q   +   + +CR  N  +++  ++P H L+D   +FS+ DL  I+ G +   LK  +  ++ HV+ C LCQ  G++CE C N + VIFPF+     +C+ C  C H +C  QS E  CPRC R   R++  E+
Sbjct:  413 IIFNIHPPL-KRDLVVAAQNFFCAGCGTPV--EPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDSIWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPGH-LTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHVAGCELCQGKGFICEFCQNTT-VIFPFQTATCRRCSACRACFHKQC-FQSSE--CPRCARITARRKLLES 656
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZWE6|PKHM3_HUMAN (Pleckstrin homology domain-containing family M member 3 OS=Homo sapiens OX=9606 GN=PLEKHM3 PE=2 SV=2)

HSP 1 Score: 132.494 bits (332), Expect = 3.794e-30
Identity = 82/237 (34.60%), Postives = 126/237 (53.16%), Query Frame = 3 
Query: 1263 LRIQSNKCPGC--SMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQ--GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            L  QS KC GC  S+  S+ KA     ++C+Y G+Y+CS CH +   +IPARI+  WD + + VS  A++ L  ++ EPL      +  L        AV+RLR + + L  ++ SCR     DL R+    P  +L     ++S+ADLQ +  G +   L   +  A  HV  C LC   G++CE+C+N  ++++PFE     +C  C    H +C  + K  PCPRC RR+ +K+
Sbjct:  507 LTAQSFKCAGCQRSIGLSNGKA-----KVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRRRI--FPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNN-GEILYPFEDISTSRCESCGAVFHSEC--KEKSVPCPRCVRRELQKK 733
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. TrEMBL
Match: A0A1S3HW32 (run domain Beclin-1-interacting and cysteine-rich domain-containing protein OS=Lingula unguis OX=7574 GN=LOC106157986 PE=4 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 2.451e-45
Identity = 97/228 (42.54%), Postives = 125/228 (54.82%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTR 1955
            Q+ +C GC      E  + +R R C Y G YFC  CHS+ +  IP RIL  WDFT +PVS  +RDLL  +H++PLFS    +  L   ++    V   R Q      F+ +CR G  L  +   LP  WL D+  ++SIADL  + SG M   LK  V +  EH   CPLCQA G+ CE C+N+ DVIFPFEL KV  C  C  C H  C++  K   CPRC R + R
Sbjct:  835 QNYRCAGCGTKV--ETGYIKRYRYCEYLGKYFCQCCHSSAITYIPGRILRKWDFTKYPVSNFSRDLLQKMHTDPLFSIQDINPTLYRRVKALDTVKEFRRQLFHFRRFVKTCRLGQSLFAELESLPSSWLDDVH-VYSIADLIKVRSGEMYDLLKKLVTKCYEHTRDCPLCQAKGFFCEFCNNRQDVIFPFELHKVENCPSCSACFHKGCYIPGK---CPRCARIEAR 1056
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. TrEMBL
Match: T2M8H1 (Run domain Beclin-1 interacting and cystein-rich containing protein OS=Hydra vulgaris OX=6087 GN=KIAA0226 PE=2 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 9.762e-42
Identity = 91/240 (37.92%), Postives = 135/240 (56.25%), Query Frame = 3 
Query: 1254 QATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSI-CPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQE 1970
            +  L+ Q  +C GC +  S   +  R  R C Y G YFC+ CH N   +IPA+IL+ WDF  +PVS  A++ +  I+++PLF  S  S  L  ++R+       R+Q   +  F+ +CR  N  + +  +LP H L++   ++SI DL   +SG ++  LK+ VM AV+H+ + C LC A G++CE C N  DV++PFEL KV  C  C  C H  C  +     CPRC+R K RK+  E
Sbjct:  650 KVMLQRQQYRCAGCGLKVS--PSLSRLFRFCEYLGKYFCTSCHQNNTSLIPAKILSKWDFKKYPVSDFAKEYIKEIYTKPLFDISGISPSLYDNVRLLALTNNWRIQLYYIKKFLSTCRMANSELGEISKLPFH-LAEETQLYSIDDLVQTKSGELQTKLKTIVMNAVQHIKVSCQLCSAKGFVCEFCKNGDDVLYPFELQKVEMCKECKTCYHRSCFAKG---FCPRCDRIKARKRMLE 883
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. TrEMBL
Match: A0A4Z2B840 (DUF4206 domain-containing protein OS=Takifugu bimaculatus OX=433685 GN=fugu_006190 PE=4 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 2.554e-41
Identity = 88/239 (36.82%), Postives = 127/239 (53.14%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCER------RKTRKQFQE 1970
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P R+L  WDF+ + +S  ARDLL+ I  +PLF+ S  + GL   ++   AV   R Q   +     +CR   +++ K   LP H   D+  +FS+ DL  + +G +   +K  +     HV+ C LCQA G++CE C N+ D+IFPF+L K  +C  C  C H  C    K+  CPRC+R      R TRK  +E
Sbjct:   87 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENAQAVVPGRVLRKWDFSKYYISNFARDLLSKIAGDPLFNLSDINSGLYKKVKALEAVRVFRTQLCHMKNLFKTCRFAKEVLDKFDILPGHLTEDL-HLFSLNDLNAVRNGNLVPRMKELLKLGTMHVAGCVLCQAKGFVCEFCGNEKDIIFPFQLHKCQRCEECHACYHRSCFRAGKD--CPRCQRLAERRERMTRKNMEE 320
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. TrEMBL
Match: V4AYT5 (DUF4206 domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_114026 PE=4 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 3.569e-41
Identity = 90/243 (37.04%), Postives = 131/243 (53.91%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERR 1946
            II  +H +       L  Q+ +C GC M    E  + +R R C Y G YFC  CHSN L  IP RI+  WDFT +PVS  ARD+L  +  +PLF+    +  +    +    +  LR Q   L  F+  C+ G  L+    +LP HW  D   ++S+ DL  +++G+M   LK+ V  ++ HV  C  CQ  G++CE+CH ++DVIFPF+L+K+  C+ C  C H +C +  K   C R E R
Sbjct:   18 IIFNIHPT-PKRNVILAKQNYRCAGCGMKV--ELDYIKRFRYCEYLGKYFCQCCHSNQLQYIPGRIIRKWDFTKYPVSNFARDVLTRLCKDPLFNIGDINPSIYRKSKTLETIRDLRKQLYHLYSFLKVCKTGFSLLEDIEKLPRHWSED-SYIYSLQDLLNVKNGSMLNQLKNIVSTSLSHVDSCQFCQGMGFICEMCH-ENDVIFPFQLNKISTCSDCHSCYHKECFVPDKCSKCARIEAR 255
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. TrEMBL
Match: A0A2T7NCZ3 (RUN domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_21607 PE=4 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 7.450e-41
Identity = 101/250 (40.40%), Postives = 135/250 (54.00%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQ 1967
            II  +HS    S   L  Q+ +C GC      E    +RLR C Y G YFC  CHSN++ VIP RI+  WDFT + VS  ARD+L  IH +PLF     +  L   +R+   V  LR Q   L+ F+  CR+   L+ +   L  HW  D   ++S+ D  ++ SG M   LK FV EA+ HV  C LCQ  G++CELC +Q  VIFPF+L +V  C  C  C H  C +  K   CP+C R + R++ Q
Sbjct:  739 IIFTVHSQEKRS-VVLSRQNMRCAGCGAKT--EPGFVKRLRYCEYMGKYFCQCCHSNSMEVIPGRIIMRWDFTQYYVSNFARDVLQKIHQQPLFHVEAINPALYRKVRLLDTVRDLRRQLGHLIVFLNICRRSTKLLEEMTSLRRHWAEDD-DIYSVEDFLMVRSGEMVAQLKQFVSEAISHVEGCQLCQGLGFICELCQDQG-VIFPFQLGRVTLCPVCQACFHRSCFIPGK---CPKCSRMEIRRKRQ 980
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Cavefish
Match: rubcn (rubicon autophagy regulator [Source:NCBI gene;Acc:103027127])

HSP 1 Score: 158.303 bits (399), Expect = 6.884e-39
Identity = 81/230 (35.22%), Postives = 120/230 (52.17%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P  +L  WDF+ + VS  ARDLL  I  +PLF+ +  +  L   ++    V  LR+Q   +     +CR   D++     +  H   D+  +FS+ DL  + SG +   L+  +     HVS C LCQA G++CE C N+ D+IFP+EL K  +C  C  C H  C    ++  CPRC+R   R++
Sbjct:  668 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENATAVVPGHVLRKWDFSKYYVSNFARDLLGKIAGDPLFNPNDVNTALYKKVKALETVRVLRMQLFHMKNLFKTCRLAKDVLEDFDSVAGHLTEDLH-LFSLNDLTAVRSGELTTKLRELLRLGSAHVSSCVLCQAKGFVCEFCGNEKDIIFPYELHKCQRCEECNACYHRTCFKSGQQ--CPRCQRLAERRE 892
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Cavefish
Match: rubcn (rubicon autophagy regulator [Source:NCBI gene;Acc:103027127])

HSP 1 Score: 157.918 bits (398), Expect = 8.173e-39
Identity = 81/230 (35.22%), Postives = 120/230 (52.17%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P  +L  WDF+ + VS  ARDLL  I  +PLF+ +  +  L   ++    V  LR+Q   +     +CR   D++     +  H   D+  +FS+ DL  + SG +   L+  +     HVS C LCQA G++CE C N+ D+IFP+EL K  +C  C  C H  C    ++  CPRC+R   R++
Sbjct:  692 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENATAVVPGHVLRKWDFSKYYVSNFARDLLGKIAGDPLFNPNDVNTALYKKVKALETVRVLRMQLFHMKNLFKTCRLAKDVLEDFDSVAGHLTEDLH-LFSLNDLTAVRSGELTTKLRELLRLGSAHVSSCVLCQAKGFVCEFCGNEKDIIFPYELHKCQRCEECNACYHRTCFKSGQQ--CPRCQRLAERRE 916
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Cavefish
Match: rubcn (rubicon autophagy regulator [Source:NCBI gene;Acc:103027127])

HSP 1 Score: 157.918 bits (398), Expect = 8.708e-39
Identity = 81/230 (35.22%), Postives = 120/230 (52.17%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P  +L  WDF+ + VS  ARDLL  I  +PLF+ +  +  L   ++    V  LR+Q   +     +CR   D++     +  H   D+  +FS+ DL  + SG +   L+  +     HVS C LCQA G++CE C N+ D+IFP+EL K  +C  C  C H  C    ++  CPRC+R   R++
Sbjct:  676 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENATAVVPGHVLRKWDFSKYYVSNFARDLLGKIAGDPLFNPNDVNTALYKKVKALETVRVLRMQLFHMKNLFKTCRLAKDVLEDFDSVAGHLTEDLH-LFSLNDLTAVRSGELTTKLRELLRLGSAHVSSCVLCQAKGFVCEFCGNEKDIIFPYELHKCQRCEECNACYHRTCFKSGQQ--CPRCQRLAERRE 900
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Cavefish
Match: plekhm3 (pleckstrin homology domain containing M3 [Source:NCBI gene;Acc:103035695])

HSP 1 Score: 137.887 bits (346), Expect = 7.448e-33
Identity = 79/238 (33.19%), Postives = 125/238 (52.52%), Query Frame = 3 
Query: 1254 QATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQ--GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            +  L  QS +C GC          R + ++CHY G+Y+C  CH + L +IPAR+L  WD + H VS  A++ L  I+ EPL      +  L        AV++LR Q + L  ++ +CR     DL R+    P  +L     ++S+ADLQ +  G +   L   +  A  HV  C LC+  G++CELCH+   +++PF+ +   +C  C    H +C ++++  PCPRC RR+  K+
Sbjct:  450 EKGLTAQSFRCAGCQRPVG---LSRGKAKVCHYSGWYYCQSCHQDNLFLIPARLLHNWDTSRHKVSKQAKEFLEFIYEEPLLDVQQLNPCLYEHSEPLAAVLKLRQQLQSLRAYLFNCRATVAEDLRRRI--FPREYLLQHIHLYSLADLQQVIDGKLAPFLSKVIKFASSHVYSCSLCREKGFICELCHD-GQILYPFQENATKRCEGCGAVFHAECRMRAQ--PCPRCVRRELHKK 679
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Cavefish
Match: rubcnl (rubicon like autophagy enhancer [Source:ZFIN;Acc:ZDB-GENE-070912-256])

HSP 1 Score: 129.413 bits (324), Expect = 4.012e-31
Identity = 75/225 (33.33%), Postives = 112/225 (49.78%), Query Frame = 3 
Query: 1284 CPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRK 1958
            C GC      E  + +RLR C Y G YFC  CHS    +IP R+L+ WDF  +PVS  ++ LL+ I  +PLF  S  +  L S  +       L+ Q   +   + +CR    ++    +LP H L++   +FS+ DL  ++ G +    K+ +  A  HV      +A G++CE C    DV+FPF+ D   +C  C  C H  C    ++  CPRC R + RK
Sbjct:  242 CAGCGTEV--EPRYIKRLRYCEYLGRYFCDSCHSGGDSMIPGRVLSRWDFGRYPVSSFSKQLLDSIWEQPLFKLSAVAKNLYSQAKELQRFRELQEQLISIKKLLKACRLSEGILSDFQQLPSH-LTEELHLFSMDDLFRVKRGQIFPTAKAMLRTAAAHVECS--SKAKGFICEFCRG-PDVLFPFQTDICTRCRDCRACFHTACF---RDESCPRCSRLQIRK 457
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008319.1 (pep scaffold:Pmarinus_7.0:GL477638:57374:63041:-1 gene:ENSPMAG00000007527.1 transcript:ENSPMAT00000008319.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.939 bits (302), Expect = 2.039e-31
Identity = 66/193 (34.20%), Postives = 99/193 (51.30%), Query Frame = 3 
Query: 1398 VIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENP 1976
            V+P R+L  WD + +PVS  AR+LL  I  +PL++    +  L   ++    V  LR Q   L   + +CR    L   S  +P H   ++  ++S+ DL  +  G +   L+  V +  +HV  C LCQA G++CE C  + D++FPFEL +  QC  C  C H KC   +    CPRC+R   R+Q    P
Sbjct:    2 VVPGRLLRRWDASRYPVSNFARELLVRIGHDPLYNLLDINPQLYRRVKALTVVQELRKQLVHLKHLLQTCRLAESLETLSSTVPGHLTEEV-DLYSLEDLLAVRRGELAPTLRQVVTQTTQHVRACQLCQARGFICEFCQKEEDILFPFELTRCQQCPGCRACYH-KCCFAAAREDCPRCKRILARRQRLAQP 192
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Sea Lamprey
Match: plekhm1 (pleckstrin homology domain containing, family M (with RUN domain) member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-2752])

HSP 1 Score: 119.398 bits (298), Expect = 1.808e-27
Identity = 75/239 (31.38%), Postives = 122/239 (51.05%), Query Frame = 3 
Query: 1251 SQATLRIQSNKCPGCS--MSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQ--GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTR 1955
            ++  L  Q+ KC GC   + F + KA     ++C Y   Y+C  CH++ L++IP R+L  WD ++  V+  A++ L  I  EPL   S  +  L   +    ++  +R Q + L  ++ +CR    ++L R+   LP  +L     ++SI DLQ +  G     L   +  A +HV  C LC   G++CE+C N S++I+PFE+    +C RC    H  C  +     CP+C RR+ R
Sbjct:  769 AEKGLDAQNCKCAGCGREIGFCYGKA-----KVCSYSRRYYCVHCHADDLVLIPGRVLHNWDVSLQKVAKQAKEFLEYIAEEPLLDVSEVNPKLYKHVAELASLRTMRQQLKSLRAYLFTCRSIVADELRRRV--LPREYLLAHMHLYSITDLQQVIDGRFAPFLAKTIKFASDHVYSCGLCSQKGFICEIC-NSSEIIYPFEVSSTIRCERCQAVFHKAC--KGSTVACPKCMRRELR 997
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005284.1 (pep scaffold:Pmarinus_7.0:GL480552:16638:25636:-1 gene:ENSPMAG00000004798.1 transcript:ENSPMAT00000005284.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 7.743e-9
Identity = 41/168 (24.40%), Postives = 80/168 (47.62%), Query Frame = 3 
Query: 2235 MRSLRGLVAALTGLFMIFSVALITTGILCKSLWSDYFRLLENSMAPIPFILIALGFIFLAVTVVGFLGTIMKNWIILVTYAGLLGSMVLTEVGAAITCGVFQTQMYSTVKLGLKNVIAN----QTAVMDSVQNKFGCCGINGYQD-YNGT------------LPSSCC 2687
            M  ++ LV     LF +  + LI  G + + +    F ++  +++  P+++IA+G +   V   G  G   +++ ++ T++  L  + + E+ A I   +F+ Q+   V+   K VI +        +D++Q +  CCG+  YQD +N T            +P SCC
Sbjct:   15 MACIKYLVLLFNLLFWLSGLGLIIVGAMAQ-MHIGAFSVVTGNLSGAPYVIIAVGVVIFVVAAFGCCGAHKESYFMVATFSVFLFLIFVAELAAGIGAYIFKDQLRDVVETKAKVVINDYPTKNKDPVDNMQKELQCCGVVHYQDWFNSTNWVTSDPNNPNSVPDSCC 181
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Sea Lamprey
Match: CD151 (CD151 molecule (Raph blood group) [Source:HGNC Symbol;Acc:HGNC:1630])

HSP 1 Score: 50.0618 bits (118), Expect = 1.155e-6
Identity = 42/163 (25.77%), Postives = 68/163 (41.72%), Query Frame = 3 
Query: 2286 FSVALITTGILCKSLWS-----DYFRLLENS-MAPIPFILIALGFIFLAVTVVGFLGTIMKNWIILVTYAGLLGSMVLTEVGAAITCGVFQTQMYSTVKLGLKNVIANQ---------TAVMDSVQNKFGCCGINGYQDYNGT------------LPSSCCPS 2693
            F   L   G++   +W+     DY  LL +S  A   +ILI  G + +   ++G    + +    L  Y GLL  + L EV A I   +++ Q+   +K  +   I            T  MD +Q +F CCG + + D+  +            +P SCC S
Sbjct:   26 FIFWLTGAGVMAVGVWTLVEKGDYLSLLASSTFAATAYILILAGSVVMLTGLLGCCAVVRERRGCLAAYCGLLLLIFLLEVIAGILAYLYRQQLSEELKSHMNKTIVESYGQPDQQRVTDAMDKLQQEFKCCGSHDWNDWQRSDWVKVAAAEGRLVPDSCCKS 188
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Nematostella
Match: EDO46085 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR10])

HSP 1 Score: 119.013 bits (297), Expect = 1.052e-29
Identity = 67/186 (36.02%), Postives = 98/186 (52.69%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSIC 1775
            +I  +H S    +  +  Q+ +C GC M    +  + +R R C+Y G YFCS CH N  MVIPARI+  WDF  + VS  A+DLLN IH +PLF+    +  L   +R    V  LR Q      F  +CR+  +L +   R+P H  ++   +FS+ DL  ++SG M    +S V  +  H+S C
Sbjct:   86 VIFHVHPS-KKRKVLMEQQNYRCAGCGMRVDPD--YMKRFRYCNYLGKYFCSSCHQNEPMVIPARIVRRWDFRKYEVSKFAKDLLNNIHYDPLFNIKDLNSALYQRVRALAEVQTLRKQLYFFRTFAQTCRKATELRQDLARIPDHIFTEE-HLFSVEDLLQVKSGEMVMLFRSLVTRSYRHISDC 267
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Nematostella
Match: EDO32187 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS4])

HSP 1 Score: 113.62 bits (283), Expect = 4.007e-28
Identity = 76/239 (31.80%), Postives = 118/239 (49.37%), Query Frame = 3 
Query: 1236 SSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQG-NDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRK 1949
            + + N Q  L  Q+ +C GC  +           ++C Y G Y+C  CH +   VIPAR++  WD   H V+   +  L  I  EPL +    +  L S +     +  LR Q + L GF+ +C+Q   D IR+ +  P  +L D    +S+ DL   +SG +  +LK  + +  +HV  C LC   G++CE C N   +I+PFE+    QC +C   SH  C    ++  CP+C RR+
Sbjct:    6 THIANEQG-LDSQNYQCKGCGRNIGMIYG---EAKVCSYDGGYYCYECHMDEDHVIPARVIYNWDLRKHRVARCTKLFLLQIEEEPLLNIDETNPTLYSVVEELEEIKVLRQQLQHLKGFLLTCKQPIADDIRRRI-WPREYLWDDIHQYSLLDLIQTQSGQLAHHLKKIIGQCTKHVYKCDLCCQKGFICEFC-NDPKIIYPFEVKTTFQCPKCKSVSHKSC---KRDENCPKCARRQ 235
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Nematostella
Match: EDO45985 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRC1])

HSP 1 Score: 88.9669 bits (219), Expect = 9.270e-19
Identity = 66/217 (30.41%), Postives = 105/217 (48.39%), Query Frame = 3 
Query: 1254 QATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCR---QGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSI-CPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSH 1892
            ++ L  Q  KC  C    S  K      RLC Y G YFC  CH N  ++IPARI+  WDFT + V+   + LL ++ ++P  +    +  L   +     + RLR +  ++  +  SCR   +   L++   R       D    +S+ DL  +E G++   +       + H+   C LCQA G++CE+C + +DVIF F+   V QC++C    H
Sbjct:  146 ESGLSTQQYKCAECRKRISFLKGEFSEARLCDYSGQYFCEECHWNDQVLIPARIIHNWDFTNYKVARQNKQLLALMLNKPQLNLEQLNPALFKFVGELREIKRLREEILIMKKYFMSCRAALESKLLLQLQDR---QHFVDNSYQYSLQDLIDVERGSLLPFVTRVHSLFLTHIKTDCELCQAKGFVCEVCKS-NDVIFAFDPHAV-QCSKCKAVLH 357
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Nematostella
Match: EDO30837 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZN5])

HSP 1 Score: 78.1814 bits (191), Expect = 6.959e-16
Identity = 44/171 (25.73%), Postives = 84/171 (49.12%), Query Frame = 3 
Query: 2235 MRSLRGLVAALTGLFMIFSVALITTGILCKSLWSDYFRLLENSMAPIPFILIALGFIFLAVTVVGFLGTIMKNWIILVTYAGLLGSMVLTEVGAAITCGVFQTQMYSTVKLGLKNVIANQ-----TAVMDSVQNKFGCCGINGYQDY-----------NGTLPSSCCPSTN 2699
            M+ ++ L+     LF +  ++++  GI  +  +SDY +L  +  A   +ILI +GF+   +  +G  G + ++  +L T+  +LG + L E+G AIT  +F++++ + +  GL   + +          + +Q    CCG   Y D+           NG++P SCC  T 
Sbjct:   10 MQCVKFLLFGFNALFWLMGLSVLAVGIWARIQFSDYMKLSSHDYATAAYILIGIGFLIAIIGFIGCCGALKEHTCLLKTFGVILGLLFLVELGTAITGYIFRSEIKTGLSDGLDTALKDYPEQGFKDAWNDMQKNLKCCGSRNYTDWFMVAWAGPNTKNGSVPESCCKDTK 180
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Nematostella
Match: EDO43827 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXD6])

HSP 1 Score: 64.6994 bits (156), Expect = 1.889e-11
Identity = 48/162 (29.63%), Postives = 79/162 (48.77%), Query Frame = 3 
Query: 2274 LFMIFSVALITTGILCKSLWSDYFRLLENSMAPIPFILIALGFIFLAVTVVGFLGTIMKNWIILVTYAGLLGSMVLTEVGAAITCGVFQTQMYSTVKLGLKNVIAN-----QTAVMDSVQNKFGCCGINGYQDY---NGTLPSSCCPSTNA------CTAGL 2717
            +F +  +AL+  G + KS + D+ ++  +S+A  P  LI +G I   V  +G  G   +N+ ++ T+A LL  + + E+ A      ++ ++   V+ GLKN + +         MD VQ +F CCG     D+   N T+P S C  TN       C  GL
Sbjct:   19 IFWLSGLALVIVGAIIKSKYGDFIQVSSSSLASGPVFLIVIGVIVAVVGFLGCCGAYKENYCMVTTFAVLLAFIFVLEIAAGALAYAYKGKLEGYVRTGLKNGVDHYDKKEYKKAMDKVQGEFKCCGYEDSNDHGYKNSTVPKS-CKDTNGTVFSKNCVKGL 179
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Medaka
Match: rubcn (rubicon autophagy regulator [Source:NCBI gene;Acc:101157851])

HSP 1 Score: 163.696 bits (413), Expect = 1.312e-40
Identity = 83/230 (36.09%), Postives = 125/230 (54.35%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P R+L  WDF+ + VS  ARDLL+ I  +PLF+ +  + GL   ++   +V  LR+Q   +   + +CR   +++ +   LP H   D+  ++S+ DL  + +G +   +K  +     HV+ C LCQA G++CE C N  D+IFPF+L K  +C  C  C H  C    K+  CPRC R   R+Q
Sbjct:  707 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENAQAVVPGRVLRKWDFSKYYVSNFARDLLSKIAGDPLFNPNDINSGLYKKIKALESVRVLRVQLFHMKNLLKTCRFAKEVLDQFDSLPGHLTEDLH-LYSLNDLTAVRNGELAPRMKELLKLGTMHVAGCMLCQAKGFVCEFCGNDKDIIFPFQLSKCQRCEECRACYHRSCFQAGKD--CPRCRRLAERRQ 931
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Medaka
Match: rubcn (rubicon autophagy regulator [Source:NCBI gene;Acc:101157851])

HSP 1 Score: 163.696 bits (413), Expect = 1.502e-40
Identity = 83/230 (36.09%), Postives = 125/230 (54.35%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P R+L  WDF+ + VS  ARDLL+ I  +PLF+ +  + GL   ++   +V  LR+Q   +   + +CR   +++ +   LP H   D+  ++S+ DL  + +G +   +K  +     HV+ C LCQA G++CE C N  D+IFPF+L K  +C  C  C H  C    K+  CPRC R   R+Q
Sbjct:  732 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENAQAVVPGRVLRKWDFSKYYVSNFARDLLSKIAGDPLFNPNDINSGLYKKIKALESVRVLRVQLFHMKNLLKTCRFAKEVLDQFDSLPGHLTEDLH-LYSLNDLTAVRNGELAPRMKELLKLGTMHVAGCMLCQAKGFVCEFCGNDKDIIFPFQLSKCQRCEECRACYHRSCFQAGKD--CPRCRRLAERRQ 956
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Medaka
Match: rubcn (rubicon autophagy regulator [Source:NCBI gene;Acc:101157851])

HSP 1 Score: 163.31 bits (412), Expect = 1.756e-40
Identity = 83/230 (36.09%), Postives = 125/230 (54.35%), Query Frame = 3 
Query: 1272 QSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQ 1961
            Q+ +C GC      +  + +RLR C Y G YFC  CH N   V+P R+L  WDF+ + VS  ARDLL+ I  +PLF+ +  + GL   ++   +V  LR+Q   +   + +CR   +++ +   LP H   D+  ++S+ DL  + +G +   +K  +     HV+ C LCQA G++CE C N  D+IFPF+L K  +C  C  C H  C    K+  CPRC R   R+Q
Sbjct:  732 QNYRCAGCGTRIDPD--YIKRLRYCEYLGRYFCQCCHENAQAVVPGRVLRKWDFSKYYVSNFARDLLSKIAGDPLFNPNDINSGLYKKIKALESVRVLRVQLFHMKNLLKTCRFAKEVLDQFDSLPGHLTEDL-HLYSLNDLTAVRNGELAPRMKELLKLGTMHVAGCMLCQAKGFVCEFCGNDKDIIFPFQLSKCQRCEECRACYHRSCFQAGKD--CPRCRRLAERRQ 956
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Medaka
Match: RUBCNL (rubicon like autophagy enhancer [Source:NCBI gene;Acc:101173346])

HSP 1 Score: 136.346 bits (342), Expect = 2.887e-32
Identity = 86/253 (33.99%), Postives = 134/253 (52.96%), Query Frame = 3 
Query: 1218 IITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENP 1976
            II  +H S   S+  + +Q+  C GC      E  + ++LR C Y G YFC  CHS +  VIPARIL+ WDF+ + VS  ++ LL+ +  EPLF  +     L S ++       L+ Q   +   + +CR    ++ +  +LP H L+++   FSI DL   + G +    ++ ++ A  HV  C LC + G++CE C  Q DVIFPF+ +   +C  C  C H +C +   ER CP+C R ++R + Q  P
Sbjct:  529 IIFTLHPSHRRSE-MVALQNFLCAGCGTEV--EPRYIKKLRYCEYLGRYFCDCCHSGSESVIPARILSCWDFSRYSVSDFSKHLLDSVWHEPLFDLACVGTTLCSRVKELSKFRDLQEQLMGIKKLLKACRFSGRVLAEFDQLPTH-LTEVPLFFSINDLLRAKKGQLAAPARALLLSATSHVESCELCLSRGFICEFCR-QKDVIFPFQRNICKRCKVCRACFHKRCFM---ERNCPKCARIQSRTEVQMRP 773
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Medaka
Match: plekhm3 (pleckstrin homology domain containing M3 [Source:NCBI gene;Acc:101163618])

HSP 1 Score: 129.413 bits (324), Expect = 3.844e-30
Identity = 80/234 (34.19%), Postives = 119/234 (50.85%), Query Frame = 3 
Query: 1254 QATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQ--GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRK 1949
            +  L  QS +C GC          R + ++C Y G+Y+C  CH +   +IPAR+L  WD T H VS  A++ L  ++ EPL      +  L         V+RLR Q + L  ++ SCR     DL R+    P  +L     ++S+ADLQ +  G +   L   +  A  HV  C LC+  G++CELCH+   VI+PF+ +    C+ C    H +C  + K +PCPRC RR+
Sbjct:  519 EKGLTAQSFRCAGCQHPIG---LSRGKAKVCCYSGWYYCQSCHQDNSFLIPARLLHNWDTTKHKVSEQAKEFLEFVYEEPLLDVHQLNPCLYQHCEPLSIVLRLRQQLQSLRAYLFSCRATIAEDLRRRI--FPREYLLQHIHLYSLADLQQVIDGKLAPFLTKVIKFASAHVFSCSLCREKGFICELCHD-GQVIYPFQENATRSCDLCGAVFHTEC--RQKAQPCPRCVRRE 744
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Planmine SMEST
Match: SMESG000019858.1 (SMESG000019858.1)

HSP 1 Score: 1168.3 bits (3021), Expect = 0.000e+0
Identity = 604/638 (94.67%), Postives = 608/638 (95.30%), Query Frame = 3 
Query:   69 FDHSILTRQIQPISNSIKYELIKPNHIRIMNLNVDKNLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQGNADVSPQVERYSESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNISALESLIMTRTLSIILVPPTPPHFTDCSSCSGTHXXXXXXXXXXXXXXXXXXXXTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 1982
             D++ILTRQIQPISNSIKYELIKPNHIRIMNLNVDK+LKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ             ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI                +PPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ
Sbjct:  113 IDYNILTRQIQPISNSIKYELIKPNHIRIMNLNVDKDLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ-------------ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI----------------IPPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 721
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Planmine SMEST
Match: SMESG000019858.1 (SMESG000019858.1)

HSP 1 Score: 1167.14 bits (3018), Expect = 0.000e+0
Identity = 604/638 (94.67%), Postives = 608/638 (95.30%), Query Frame = 3 
Query:   69 FDHSILTRQIQPISNSIKYELIKPNHIRIMNLNVDKNLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQGNADVSPQVERYSESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNISALESLIMTRTLSIILVPPTPPHFTDCSSCSGTHXXXXXXXXXXXXXXXXXXXXTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 1982
             D++ILTRQIQPISNSIKYELIKPNHIRIMNLNVDK+LKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ             ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI                +PPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ
Sbjct:  109 IDYNILTRQIQPISNSIKYELIKPNHIRIMNLNVDKDLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ-------------ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI----------------IPPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 717
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Planmine SMEST
Match: SMESG000019858.1 (SMESG000019858.1)

HSP 1 Score: 1163.67 bits (3009), Expect = 0.000e+0
Identity = 604/639 (94.52%), Postives = 608/639 (95.15%), Query Frame = 3 
Query:   69 FDHSILTRQIQPISNSIKYELIKPNHIRIMNLNVDKNLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQGNADVSPQVERYSESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNISALESLIMTRTLSIILVPPTPPHFTDCSSCSGTHXXXXXXXXXXXXXXXXXXXXTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQ-GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 1982
             D++ILTRQIQPISNSIKYELIKPNHIRIMNLNVDK+LKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ             ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI                +PPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQ GNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ
Sbjct:  113 IDYNILTRQIQPISNSIKYELIKPNHIRIMNLNVDKDLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ-------------ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI----------------IPPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQVGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 722
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Planmine SMEST
Match: SMESG000019858.1 (SMESG000019858.1)

HSP 1 Score: 1111.67 bits (2874), Expect = 0.000e+0
Identity = 578/609 (94.91%), Postives = 580/609 (95.24%), Query Frame = 3 
Query:  156 MNLNVDKNLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQGNADVSPQVERYSESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNISALESLIMTRTLSIILVPPTPPHFTDCSSCSGTHXXXXXXXXXXXXXXXXXXXXTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 1982
            MNLNVDK+LKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ             ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI                +PPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ
Sbjct:    1 MNLNVDKDLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ-------------ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI----------------IPPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 580
[Close]
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Planmine SMEST
Match: SMESG000019858.1 (SMESG000019858.1)

HSP 1 Score: 1084.32 bits (2803), Expect = 0.000e+0
Identity = 565/595 (94.96%), Postives = 566/595 (95.13%), Query Frame = 3 
Query:  198 MVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQGNADVSPQVERYSESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNISALESLIMTRTLSIILVPPTPPHFTDCSSCSGTHXXXXXXXXXXXXXXXXXXXXTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMXXXXXXXXXXXFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 1982
            MVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ             ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI                +PPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ
Sbjct:    1 MVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQ-------------ESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNI----------------IPPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESSTMSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGPMKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIVDNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNSTAVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQCLPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYYGYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSASHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCHWLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLCELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTRKQFQENPFQ 566
The following BLAST results are available for this feature:
BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RUBCN3.142e-3835.65rubicon autophagy regulator [Source:HGNC Symbol;Ac... [more]
RUBCN3.409e-3835.65rubicon autophagy regulator [Source:HGNC Symbol;Ac... [more]
RUBCN4.768e-3835.65rubicon autophagy regulator [Source:HGNC Symbol;Ac... [more]
RUBCNL8.170e-3534.13rubicon like autophagy enhancer [Source:HGNC Symbo... [more]
RUBCNL1.500e-3434.13rubicon like autophagy enhancer [Source:HGNC Symbo... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Y56A3A.163.486e-2331.02pep chromosome:WBcel235:III:11911111:11914315:-1 g... [more]
Y56A3A.161.056e-2130.77pep chromosome:WBcel235:III:11911001:11914317:-1 g... [more]
cup-145.056e-2127.85pep chromosome:WBcel235:II:13855788:13860058:-1 ge... [more]
cup-145.056e-2127.85pep chromosome:WBcel235:II:13855788:13860079:-1 ge... [more]
cup-145.056e-2127.85pep chromosome:WBcel235:II:13855788:13861040:-1 ge... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG127723.860e-2731.47gene:FBgn0030055 transcript:FBtr0331728[more]
CG127723.860e-2731.47gene:FBgn0030055 transcript:FBtr0071221[more]
CG115342.964e-2131.10gene:FBgn0046296 transcript:FBtr0075995[more]
Plekhm15.557e-1926.44gene:FBgn0034694 transcript:FBtr0071758[more]
Tsp47F2.923e-1227.81gene:FBgn0033629 transcript:FBtr0088151[more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rubcnl9.033e-4033.48rubicon like autophagy enhancer [Source:ZFIN;Acc:Z... [more]
rubcn1.210e-3937.23rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-G... [more]
rubcn1.217e-3937.23rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-G... [more]
rubcn1.424e-3937.23rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-G... [more]
rubcn2.450e-3533.46rubicon autophagy regulator [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000046880.13.887e-4036.95RUN domain and cysteine-rich domain containing, Be... [more]
ENSXETT00000046860.15.057e-4036.95RUN domain and cysteine-rich domain containing, Be... [more]
ENSXETT00000046840.15.704e-4036.95RUN domain and cysteine-rich domain containing, Be... [more]
ENSXETT00000046930.15.998e-4036.95RUN domain and cysteine-rich domain containing, Be... [more]
ENSXETT00000046922.16.625e-4036.95RUN domain and cysteine-rich domain containing, Be... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rubcn1.097e-3936.36RUN domain and cysteine-rich domain containing, Be... [more]
Rubcn1.291e-3936.36RUN domain and cysteine-rich domain containing, Be... [more]
Rubcn1.675e-3936.36RUN domain and cysteine-rich domain containing, Be... [more]
Rubcn1.752e-3936.36RUN domain and cysteine-rich domain containing, Be... [more]
Plekhm34.633e-3034.18pleckstrin homology domain containing, family M, m... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q80U62|RUBIC_MOUSE1.225e-3836.36Run domain Beclin-1-interacting and cysteine-rich ... [more]
sp|Q92622|RUBIC_HUMAN2.290e-3735.65Run domain Beclin-1-interacting and cysteine-rich ... [more]
sp|A7E316|PACER_BOVIN6.250e-3534.10Protein associated with UVRAG as autophagy enhance... [more]
sp|Q9H714|PACER_HUMAN2.897e-3334.13Protein associated with UVRAG as autophagy enhance... [more]
sp|Q6ZWE6|PKHM3_HUMAN3.794e-3034.60Pleckstrin homology domain-containing family M mem... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3HW322.451e-4542.54run domain Beclin-1-interacting and cysteine-rich ... [more]
T2M8H19.762e-4237.92Run domain Beclin-1 interacting and cystein-rich c... [more]
A0A4Z2B8402.554e-4136.82DUF4206 domain-containing protein OS=Takifugu bima... [more]
V4AYT53.569e-4137.04DUF4206 domain-containing protein (Fragment) OS=Lo... [more]
A0A2T7NCZ37.450e-4140.40RUN domain-containing protein OS=Pomacea canalicul... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rubcn6.884e-3935.22rubicon autophagy regulator [Source:NCBI gene;Acc:... [more]
rubcn8.173e-3935.22rubicon autophagy regulator [Source:NCBI gene;Acc:... [more]
rubcn8.708e-3935.22rubicon autophagy regulator [Source:NCBI gene;Acc:... [more]
plekhm37.448e-3333.19pleckstrin homology domain containing M3 [Source:N... [more]
rubcnl4.012e-3133.33rubicon like autophagy enhancer [Source:ZFIN;Acc:Z... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000008319.12.039e-3134.20pep scaffold:Pmarinus_7.0:GL477638:57374:63041:-1 ... [more]
plekhm11.808e-2731.38pleckstrin homology domain containing, family M (w... [more]
ENSPMAT00000005284.17.743e-924.40pep scaffold:Pmarinus_7.0:GL480552:16638:25636:-1 ... [more]
CD1511.155e-625.77CD151 molecule (Raph blood group) [Source:HGNC Sym... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO460851.052e-2936.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321874.007e-2831.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459859.270e-1930.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308376.959e-1625.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO438271.889e-1129.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rubcn1.312e-4036.09rubicon autophagy regulator [Source:NCBI gene;Acc:... [more]
rubcn1.502e-4036.09rubicon autophagy regulator [Source:NCBI gene;Acc:... [more]
rubcn1.756e-4036.09rubicon autophagy regulator [Source:NCBI gene;Acc:... [more]
RUBCNL2.887e-3233.99rubicon like autophagy enhancer [Source:NCBI gene;... [more]
plekhm33.844e-3034.19pleckstrin homology domain containing M3 [Source:N... [more]
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BLAST of run domain Beclin-1-interacting and cysteine-rich domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019858.10.000e+094.67SMESG000019858.1[more]
SMESG000019858.10.000e+094.67SMESG000019858.1[more]
SMESG000019858.10.000e+094.52SMESG000019858.1[more]
SMESG000019858.10.000e+094.91SMESG000019858.1[more]
SMESG000019858.10.000e+094.96SMESG000019858.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011903 ID=SMED30011903|Name=run domain Beclin-1-interacting and cysteine-rich domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3548bp
GGTGACCTACATTAATCGGTATGTATCTTACTGAAATGTGATTTGTGATC
TACATTAATCCAGATATATTTGACCACAGCATTCTCACCCGCCAAATTCA
ACCAATAAGCAACTCCATAAAATACGAACTGATTAAACCGAACCATATCC
GTATTATGAATCTAAACGTCGACAAGAACTTGAAGCCCTCTTATCTAATG
GTAAAGAAGAACAGCTGGGTATACAGTGATGTGGCTCAGGAAAACCAGCG
GCTGAGTAGTATAATGCACTATCTAATGTCTACCAAGGCAACGGGGCAGC
AAGGTAATGCTGATGTTTCCCCGCAAGTTGAAAGATATTCAGAATCTCGA
CAAAAACGAGACAGATTTACATCATTGGGCAATCTAGTAAACTTGTCCGT
TCCAAAAGCTTTAACCCGTTCAAAATCCCTTGGCAATATCAGTGCGTTAG
AATCGCTTATAATGACCAGAACATTGAGCATTATTCTAGTACCGCCGACG
CCGCCGCATTTCACTGATTGCTCGAGCTGCTCCGGCACGCATTTGCAATC
CCCAGAGAGCCGTAGCCAACAGCAGAGATCATCGGAACTCCTGGAATCTA
GCACCATGAGTCAAATCATGGAGAGCCTCGAATTTCAGGTGAGCCAGAGG
AACGAGCGGTCGCATTTCATTCTCAGTGAGCTGTTGATTCAGGCCATTGA
GTTTCTCTACTCAGATGAGTTGTTGCGGAGGTCTGGCGTCAATTTATGCG
GGCCGATGAAGCCTTCAATTTTGAAGCCCTTCAACACGGCCGCCTGTCCA
ATCGTGCTCAATATGCTCAACACATTCCATCCTGACCCTTCGTCACACCC
GGAACAGTGTCACAGCCTCTCCAGTAAGGCGGACGCGGTGGCAGTGCTCA
TTGTTGATAACGTGTTACACGTCTGTGTCAGCCTGGGCATCCAGCACAAA
TTCAAACAGGTTTTCCCATCAAGCCTGCAAATCCTCCAACATCAGCTGGA
ACAGCAACGGGAGTCCAGCAGTTATGACCGGCCTGTTAGGTTCCAGAATT
CCACTGCCGTTATATCCGAGGTTCACCAAGACAACCAAACTGACAGCCAA
TCAGAGACAGCCACTGAAAACCTGATACGGACAGCCGTAGAAGCTCAAAG
CTTGCCCTTGAACATCCAAGTTGGGGAATATCCAGTGATGCAAGGGGATC
AGTGCCTGCCGACGTATATTATCACCCGGATGCACAGCTCGCTCGGCAAT
TCCCAGGCAACGCTCAGAATCCAGTCCAACAAATGTCCCGGATGTTCCAT
GTCATTCTCACACGAGAAAGCTCACCGCCGCCGGCTCAGATTGTGCCATT
ACTATGGATACTACTTCTGCTCGGTGTGCCACAGCAACACGCTGATGGTG
ATTCCTGCCCGCATATTGACCGGCTGGGATTTCACCATGCATCCCGTCAG
CTGTTTGGCCCGCGACTTGCTCAATGTCATTCATTCGGAACCTTTGTTCT
CTGCTTCTCATTTCTCTGATGGATTGCGTTCTAGTTTGCGGGTGTTTGGT
GCCGTTATGCGGTTGCGGCTCCAGGGCCGCCTGCTGCTGGGCTTCATTGG
TTCCTGTCGTCAAGGAAATGATCTGATCAGGAAATCGATGCGGTTGCCTT
GCCATTGGCTGTCGGATATTTGCCCGATGTTCTCGATTGCCGACCTGCAA
CTCATCGAATCCGGTACAATGGAACGGAACCTGAAATCATTTGTCATGGA
AGCTGTGGAACACGTATCGATTTGCCCGCTCTGTCAGGCGCACGGATATT
TGTGCGAGCTTTGTCATAATCAATCAGATGTCATATTCCCATTCGAACTT
GACAAAGTCCACCAATGCAATCGCTGTTTCGGCTGTTCTCACATCAAGTG
CCACCTCCAGTCCAAGGAGCGTCCTTGTCCCAGATGTGAAAGGCGCAAAA
CCAGAAAACAGTTCCAAGAGAATCCTTTCCAATGAGAGAAATTATTTGAT
AAAGTTTTTTAATGAGATATTTGTAATCAATAAATTATTATTATTATTAT
TATGGATTTGCTGTTGTTGTGCTGTTGTTGTGCTGTTGGTGTGCATGTCT
GTGATTCTACAATTGTTGTCAAGGTCAACCGATTTGTATAATTGGCATAA
TTAATATTCCCAACTGTTCATTTCTCATTCTGCCTCAGGAATTATTGGGA
CATGTTTTCAGATTGCAATTGCCCGAATTTGGAAATGCGGAGCTTGAGAG
GGCTCGTTGCAGCACTAACTGGCCTCTTCATGATATTTTCTGTGGCGCTC
ATCACAACAGGAATCCTATGCAAATCGCTTTGGTCAGATTATTTTAGGCT
GTTGGAGAATTCCATGGCTCCGATCCCCTTCATTTTGATAGCCCTCGGAT
TTATATTCCTGGCCGTGACAGTTGTCGGATTTCTCGGTACAATTATGAAA
AATTGGATAATATTAGTCACGTACGCGGGGCTGCTCGGATCCATGGTATT
AACAGAAGTTGGAGCTGCAATTACGTGTGGAGTGTTTCAAACTCAGATGT
ATTCCACAGTGAAATTGGGTCTGAAGAATGTTATAGCAAACCAGACCGCA
GTTATGGATTCAGTGCAAAATAAGTTCGGCTGTTGTGGAATCAACGGATA
TCAGGACTACAACGGCACCCTTCCTAGCAGTTGCTGCCCATCAACTAATG
CATGCACTGCTGGCTTAGCTGCGCCTACAGGCTGCCTTTCTGCATTTGTC
AGTGTCAGTTCTAGCAGTATCAGTCTTGTAATTGGACTTACAATCGGAGC
CATCATATTTGAGACTCTTGCAATTATTGTTATCGCAAGACTGTATAATC
TTTTAAAATCGTCAAACAAGCCCCCTCCAGAATGATTTATCAGCAGGGTT
TATTTAATGGGAAATTGGTGAACATTGACGAAGGTTTAGGGTGTAGCTGC
AATCCCTTTCCGTGAATTGACATGATCATAATTTTGTGACATAATCGCAA
TTGCCTCGGGTTTGGGTTAAATGTATTTGAGTTGAGTTTGGCATTACTGA
CATTAGCTGACATTGCCTTTCAATCATATCGTTTGGGATTGGCACAATAT
AAATACCGCAACGTAACTTTTATAGTGCTCTAACTGATCCATCATTCACT
TCAATGAGATTTCATGCAGGCACCAGGACAATCAATAAATTAGTACACAT
TCACATTTGACATAAGGAGAACTCTCTAAAGTTCAGTGAATGATGATCCA
ATTGACTATTGCAATTATAATTATCAGGTTTCTTACATCAAGCTCATGCC
GTTAAGCGGCCGTTGAGGAATCCTTAAGTCTAAATGTCTCTCTGAACGTA
AAGCAATTATATATCAGTAAAAGTTGTCTATAAGATGGAATGTTGAGTGG
CGATTGCATGGGGGAATCCTCACTATCACTTACTTATGTATATCAATGGT
TTGCCGTTTTCATTATTAATGTCCATTCTACTGTATTTTAGGTGATCAAC
ACGTCACGACCTTTCAATAACCTGAAAATTTGCTTTTTTATTCCATCA
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protein sequence of SMED30011903-orf-1

>SMED30011903-orf-1 ID=SMED30011903-orf-1|Name=SMED30011903-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=116bp
MARQPHRFPDQIISLTTGTNEAQQQAALEPQPHNGTKHPQTRTQSIREMR
SREQRFRMNDIEQVAGQTADGMHGEIPAGQYAGRNHHQRVAVAHRAEVVS
IVMAQSEPAAVSFLV*
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protein sequence of SMED30011903-orf-2

>SMED30011903-orf-2 ID=SMED30011903-orf-2|Name=SMED30011903-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=610bp
MNLNVDKNLKPSYLMVKKNSWVYSDVAQENQRLSSIMHYLMSTKATGQQG
NADVSPQVERYSESRQKRDRFTSLGNLVNLSVPKALTRSKSLGNISALES
LIMTRTLSIILVPPTPPHFTDCSSCSGTHLQSPESRSQQQRSSELLESST
MSQIMESLEFQVSQRNERSHFILSELLIQAIEFLYSDELLRRSGVNLCGP
MKPSILKPFNTAACPIVLNMLNTFHPDPSSHPEQCHSLSSKADAVAVLIV
DNVLHVCVSLGIQHKFKQVFPSSLQILQHQLEQQRESSSYDRPVRFQNST
AVISEVHQDNQTDSQSETATENLIRTAVEAQSLPLNIQVGEYPVMQGDQC
LPTYIITRMHSSLGNSQATLRIQSNKCPGCSMSFSHEKAHRRRLRLCHYY
GYYFCSVCHSNTLMVIPARILTGWDFTMHPVSCLARDLLNVIHSEPLFSA
SHFSDGLRSSLRVFGAVMRLRLQGRLLLGFIGSCRQGNDLIRKSMRLPCH
WLSDICPMFSIADLQLIESGTMERNLKSFVMEAVEHVSICPLCQAHGYLC
ELCHNQSDVIFPFELDKVHQCNRCFGCSHIKCHLQSKERPCPRCERRKTR
KQFQENPFQ*
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protein sequence of SMED30011903-orf-3

>SMED30011903-orf-3 ID=SMED30011903-orf-3|Name=SMED30011903-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=228bp
MFSDCNCPNLEMRSLRGLVAALTGLFMIFSVALITTGILCKSLWSDYFRL
LENSMAPIPFILIALGFIFLAVTVVGFLGTIMKNWIILVTYAGLLGSMVL
TEVGAAITCGVFQTQMYSTVKLGLKNVIANQTAVMDSVQNKFGCCGINGY
QDYNGTLPSSCCPSTNACTAGLAAPTGCLSAFVSVSSSSISLVIGLTIGA
IIFETLAIIVIARLYNLLKSSNKPPPE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000419prepharyngeal region
PLANA:0000484secretory system
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR000301Tetraspanin
IPR018499Tetraspanin/Peripherin
IPR008952Tetraspanin_EC2_sf
IPR025258Zf-RING_9
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005654nucleoplasm
GO:0005764lysosome
GO:0005768endosome
GO:0005769early endosome
GO:0005770late endosome
GO:0005829cytosol
GO:0043231intracellular membrane-bounded organelle
Vocabulary: biological process
TermDefinition
GO:0002376immune system process
GO:0006897endocytosis
GO:0006914autophagy
GO:0010507negative regulation of autophagy
GO:0043553negative regulation of phosphatidylinositol 3-kinase activity
GO:0045806negative regulation of endocytosis
GO:1901097negative regulation of autophagosome maturation
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR025258Putative zinc-RING and/or ribbonSMARTSM01175DUF4206_2coord: 395..601
e-value: 5.5E-66
score: 235.2
IPR025258Putative zinc-RING and/or ribbonPFAMPF13901zf-RING_9coord: 395..598
e-value: 6.8E-54
score: 183.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 124..148
NoneNo IPR availablePANTHERPTHR45971FAMILY NOT NAMEDcoord: 334..602