Alpha-mannosidase 2C1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30011873 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Human
Match: MAN2C1 (mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]) HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0 Identity = 403/1109 (36.34%), Postives = 576/1109 (51.94%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSW--------PLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPF 3323
A K+WRTT ER++KF+S YFTD N+ + + + +T +L +++++ + A + FG TW WFR+E +P W + L W S+ E LV G +QGL +T+ L + DP + + LYV+ +C+ L GAG +I APD K F+L A L + + DL+LLL IA+ L +++ ++QAL+ ANQ VN+ + + A+ RFF G + ++HA GHCHIDTAWLW F ET RK ARSW T + L++++P F CSQAQQ++W++ YP L+ RI+ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ N+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + +S LES + + LCTW GELFLELHNGTYTT Q+K GN CE+++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V ++A + + + + + A+ L P ++N W P + L+ +P A + ++ + V D V +D N V +D R+ + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + + +A Y Q G RPTH NTSWD A++EV H W+ L E +G+A+ + +G+SV G + LSLLRAP +PDATAD H F YAL P + A +W+ S+ SP+ V ++ +K Q R V+RL+E G L S P++ A L ++L ER G+L + L PF
Sbjct: 4 APALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLS--SFLTPERLPYQEAVQRDFRPA------------------QVGDSFGPTWWTCWFRVELTIPEAWVGQEVH----LCWESDGEGLVWRD-GEPVQGLTKEGEKTSYVLTDRLGERDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAVFHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNV----CDPAQPETFPVAQALASRFFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQAQQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPRQLFSALES-DSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERILHDVELLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIRSHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLALVTVPSMGYAPVPPPTSLQPLLPQQPVFVVQETDGSVTLD-------------NGIIRVKLDPTGRLTSLVLVA--SGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGR--HEFTYALMPHKAPSP------------APATSWSA----------------------FSVSSPA---VVLETVKQAESSPQR-----RSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLL-ERPDPAGHLTLRDNRLKLTFSPF 1003
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Human
Match: MAN2C1 (mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]) HSP 1 Score: 608.601 bits (1568), Expect = 0.000e+0 Identity = 409/1116 (36.65%), Postives = 584/1116 (52.33%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSW------PLAVQNSAAGLLVIPP---------CXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPF 3323
A K+WRTT ER++KF+S YFTD N+ + + + +T +L +++++ + A + FG TW WFR+E +P W + L W S+ E LV G +QGL +T+ L + DP + + LYV+ +C+ L GAG +I APD K F+L A L + + DL+LLL IA+ L +++ ++QAL+ ANQ VN+ + + A+ RFF G + ++HA GHCHIDTAWLW F ET RK ARSW T + L++++P F CSQAQQ++W++ YP L+ RI+ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ N+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + +S LES + + LCTW GELFLELHNGTYTT Q+K GN CE+++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V ++A + + + + + A+ L P ++N W L A L + P CS ++ T+ A ++ P P + D L N V +D R+ + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + + +A Y Q G RPTH NTSWD A++EV H W+ L E +G+A+ + +G+SV G + LSLLRAP +PDATAD H F YAL P + + A + + A N+ L + S+ SP+ V ++ +K Q R V+RL+E G L S P++ A L ++L ER G+L + L PF
Sbjct: 4 APALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLS--SFLTPERLPYQEAVQRDFRPA------------------QVGDSFGPTWWTCWFRVELTIPEAWVGQEVH----LCWESDGEGLVWRD-GEPVQGLTKEGEKTSYVLTDRLGERDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAVFHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNV----CDPAQPETFPVAQALASRFFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQAQQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPRQLFSALES-DSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERILHDVELLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIRSHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLGLTPSPGDSAQHGLCSCSSPHLTAAPAAPAACVRSARAPTDSASRPPPTKTDGSVTL---DNGIIRVKLDPTGRLTSLVLVA--SGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGR--HEFTYALMPHKGSFQD-----AGVIQAAYSLNFP------LLALPAPSPAPATSWSAFSVSSPA---VVLETVKQAESSPQR-----RSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLL-ERPDPAGHLTLRDNRLKLTFSPF 1043
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Human
Match: MAN2C1 (mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]) HSP 1 Score: 608.216 bits (1567), Expect = 0.000e+0 Identity = 405/1109 (36.52%), Postives = 581/1109 (52.39%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSW--------PLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPF 3323
A K+WRTT ER++KF+S YFTD N+ + + + +T +L +++++ + A + FG TW WFR+E +P W + L W S+ E LV G +QGL +T+ L + DP + + LYV+ +C+ L GAG +I APD K F+L A L + + DL+LLL IA+ L +++ ++QAL+ ANQ VN+ + + A+ RFF G + ++HA GHCHIDTAWLW F ET RK ARSW T + L++++P F CSQAQQ++W++ YP L+ RI+ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ N+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + +S LES + + LCTW GELFLELHNGTYTT Q+K GN CE+++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V ++A + + + + + A+ L P ++N W P + L+ +P A + ++ + V D V +D N V +D R+ + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + + +A Y Q G RPTH NTSWD A++EV H W+ L E +G+A+ + +G+SV G + LSLLRAP +PDATAD H F YAL P + + A + + A N+ L + S+ SP+ V ++ +K Q R V+RL+E G L S P++ A L ++L ER G+L + L PF
Sbjct: 4 APALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLS--SFLTPERLPYQEAVQRDFRPA------------------QVGDSFGPTWWTCWFRVELTIPEAWVGQEVH----LCWESDGEGLVWRD-GEPVQGLTKEGEKTSYVLTDRLGERDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAVFHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNV----CDPAQPETFPVAQALASRFFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQAQQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPRQLFSALES-DSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERILHDVELLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIRSHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLALVTVPSMGYAPVPPPTSLQPLLPQQPVFVVQETDGSVTLD-------------NGIIRVKLDPTGRLTSLVLVA--SGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGR--HEFTYALMPHKGSFQD-----AGVIQAAYSLNFP------LLALPAPSPAPATSWSAFSVSSPA---VVLETVKQAESSPQR-----RSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLL-ERPDPAGHLTLRDNRLKLTFSPF 1026
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Human
Match: MAN2C1 (mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]) HSP 1 Score: 454.521 bits (1168), Expect = 6.485e-142 Identity = 295/783 (37.68%), Postives = 419/783 (53.51%), Query Frame = 3
Query: 1017 SQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSW--------PLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPF 3323
++AQQ++W++ YP L+ RI+ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ N+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + +S LES + + LCTW GELFLELHNGTYTT Q+K GN CE+++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V ++A + + + + + A+ L P ++N W P + L+ +P A + ++ + V D V +D N V +D R+ + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + + +A Y Q G RPTH NTSWD A++EV H W+ L E +G+A+ + +G+SV G + LSLLRAP +PDATAD H F YAL P + + A + + A N+ L + S+ SP+ V ++ +K Q R V+RL+E G L S P++ A L ++L ER G+L + L PF
Sbjct: 199 AKAQQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPRQLFSALES-DSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERILHDVELLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIRSHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLALVTVPSMGYAPVPPPTSLQPLLPQQPVFVVQETDGSVTLD-------------NGIIRVKLDPTGRLTSLVLVA--SGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGR--HEFTYALMPHKGSFQD-----AGVIQAAYSLNFP------LLALPAPSPAPATSWSAFSVSSPA---VVLETVKQAESSPQR-----RSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLL-ERPDPAGHLTLRDNRLKLTFSPF 927 HSP 2 Score: 81.6481 bits (200), Expect = 5.725e-15 Identity = 68/226 (30.09%), Postives = 104/226 (46.02%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEA 719
A K+WRTT ER++KF+S YFTD N+ + + + +T +L +++++ + A + FG TW WFR+E +P W + L W S+ E LV G +QGL +T+ L + DP + + LYV+ +C+ L GAG +I APD K F+L A L + + DL+LLL IA+A
Sbjct: 4 APALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLS--SFLTPERLPYQEAVQRDFRPA------------------QVGDSFGPTWWTCWFRVELTIPEAWVGQEVH----LCWESDGEGLVWRD-GEPVQGLTKEGEKTSYVLTDRLGERDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAVFHRDVHMLLVDLELLLGIAKA 201
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Human
Match: MAN2C1 (mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]) HSP 1 Score: 161.77 bits (408), Expect = 3.873e-42 Identity = 116/371 (31.27%), Postives = 173/371 (46.63%), Query Frame = 3
Query: 2223 ISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCC-TPESIDLLMCPFAI 3329
+ N V +D R+ + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + + +A Y Q G RPTH NTSWD A++EV H W+ L E +G+A+ + +G+SV G + LSLLRAP +PDATAD H F YAL P + + A + + A N+ + S+ SP+ V ++ +K Q R V+RL+E G L S P++ A L ++L ER G+L P L P A+
Sbjct: 52 LDNGIIRVKLDPTGRLTSLVLVA--SGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGR--HEFTYALMPHKGSFQD-----AGVIQAAYSLNFPLLALPAPSPAPATSWSA------FSVSSPA---VVLETVKQAESSPQR-----RSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLL-ERPDPAGHLTSGQPPEAHLFSLPSAV 392
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Celegans
Match: aman-2 (Alpha-mannosidase [Source:UniProtKB/TrEMBL;Acc:Q2PJ74]) HSP 1 Score: 64.6994 bits (156), Expect = 4.014e-10 Identity = 52/202 (25.74%), Postives = 88/202 (43.56%), Query Frame = 3
Query: 873 RLSLHAIGHCHIDTAWLWRFGETRRKLARS-WSTVVGLLDKHPSMAFVCSQAQQMD-WLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFG--AFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKF---PHHSFIWQGLDGSR----VVTHFPPGDSYSM--TCSVPE 1439
RL + I H H D W+ F E + R+ + L + M F+ ++ + W R+ ++ ++K E +F V G WV D S+ + G + + H G A + W D FG SP +P ++ A I+ + Q++ +S+ + + F W+ L GS + +H P SY + TC PE
Sbjct: 180 RLEVIVIPHSHCDPGWIMTFEEYYNRQTRNILDGMAKHLAEKDEMRFIYAEISFFETWWRDQADEIKKKVKGYLEAGKFEIVTGGWVMTDEANAHYHSMITELFEGHEWIQNHLGKSAIPQSHWSIDPFGLSPSMPHLLTSANITNAVIQRVHYSVKRELALKKNLEFYWRQLFGSTGHPDLRSHIMPFYSYDIPHTCG-PE 380
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Fly
Match: alpha-Man-IIa (gene:FBgn0011740 transcript:FBtr0082031) HSP 1 Score: 56.9954 bits (136), Expect = 1.087e-7 Identity = 46/199 (23.12%), Postives = 86/199 (43.22%), Query Frame = 3
Query: 873 RLSLHAIGHCHIDTAWLWRFGETRRKLARS-WSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDL----FIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHH---SFIWQGL----DGSRVVTHFPPGDSYSM--TC 1427
+L + + H H D W+ F E + + S + L +P M F+ + ++ + Y DL +++K++ + Q V G WV D ++ Q GQ + K+ W D FG+SP +P I++++G + Q+ +S+ + F+W+ + + + TH P SY + TC
Sbjct: 143 KLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWA---EISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTC 338
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Fly
Match: alpha-Man-IIa (gene:FBgn0011740 transcript:FBtr0334302) HSP 1 Score: 56.9954 bits (136), Expect = 1.153e-7 Identity = 46/199 (23.12%), Postives = 86/199 (43.22%), Query Frame = 3
Query: 873 RLSLHAIGHCHIDTAWLWRFGETRRKLARS-WSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDL----FIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHH---SFIWQGL----DGSRVVTHFPPGDSYSM--TC 1427
+L + + H H D W+ F E + + S + L +P M F+ + ++ + Y DL +++K++ + Q V G WV D ++ Q GQ + K+ W D FG+SP +P I++++G + Q+ +S+ + F+W+ + + + TH P SY + TC
Sbjct: 144 KLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWA---EISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTC 339
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Fly
Match: LManII (gene:FBgn0027611 transcript:FBtr0080031) HSP 1 Score: 51.6026 bits (122), Expect = 5.938e-6 Identity = 42/161 (26.09%), Postives = 68/161 (42.24%), Query Frame = 3
Query: 876 LSLHAIGHCHIDTAWL-----WRFG-ETRRKLARSW---STVVGLLDKHPSMAFV-CSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREF--WLPDTFGYSPQLPQIMRQAGISRFMTQKLSW 1322
L++H + H H D WL + +G ET+ + A +VV L + P F+ A W +E P + +K L E+ + +GG W D +S+ QF +G + FG R W D FG+S ++ + Q G +L +
Sbjct: 47 LNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDY 207
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Fly
Match: LManII (gene:FBgn0027611 transcript:FBtr0080030) HSP 1 Score: 51.2174 bits (121), Expect = 6.300e-6 Identity = 42/161 (26.09%), Postives = 68/161 (42.24%), Query Frame = 3
Query: 876 LSLHAIGHCHIDTAWL-----WRFG-ETRRKLARSW---STVVGLLDKHPSMAFV-CSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREF--WLPDTFGYSPQLPQIMRQAGISRFMTQKLSW 1322
L++H + H H D WL + +G ET+ + A +VV L + P F+ A W +E P + +K L E+ + +GG W D +S+ QF +G + FG R W D FG+S ++ + Q G +L +
Sbjct: 47 LNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDY 207
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Zebrafish
Match: man2c1 (mannosidase, alpha, class 2C, member 1 [Source:ZFIN;Acc:ZDB-GENE-101103-4]) HSP 1 Score: 626.706 bits (1615), Expect = 0.000e+0 Identity = 419/1117 (37.51%), Postives = 595/1117 (53.27%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRL-LYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSET-AYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDA--YW------AHRSVLDWCHQVTHSLASILRMVPPFLINPTSW--------PLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLE-NSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
+ KN RT ER++KF+SD YFTD N+ + D+ L I S+ L +K +IP ++ N K FG TW WF++ +P W + L W S+ E +V + +QGL +T+ L D + SH + LYV+ +C+ LFGAG +I APD N+ F L A L + + + D ++LLD+ + L E +QAL AN+ VN+ S AR +FFA K G + +HA+GHCHID+AWLW + ET RK ARSW TV+ L++K+P F CSQAQQ W++ YP LF IK ++ QFIPVGGTWVEMD NLP ES+ RQFL+GQNF+K+ FG +C+EFWLPDTFGYS QLPQIM+ GISRF+TQKLSW+L+N FPH++F W+G+DG+ V+THFPPG+SY M V +++ + N+ DKGR + + L+G GDGG GPT ML L RV + D LP++ STPD +S LES + LC W GELFLELHNGTYTTQ ++K+ N CE ++ VE+ S + + DS ++++ W+L+LLNQFHDV+PG+ I V +DA Y+ A R +LD C + S + + ++N SW P+ + L+ +P +A T+++ V T+ I ++ N +D L R++ + L + IS GNQ ++DDVPL+WDAWDVMDYHL+T + +V + A V +S VS F L N + ++Q + + + +F T + W E H+ +KV+ P + +PEA Y Q G RPTHRNTSWD A++EV GH W L E +G+A+ ++ +G SV + LSLLRAP +PD AD H+F+YAL P T AVI + A FN+ + V P S S S+ + ++ IK K +N ++RL+E G R V L +S ++ ++L ER + T I L PF I S+++
Sbjct: 6 VLKNRRTLLERVEKFISDIYFTDCNLRGRLFGDIYPLESI---------------SVFLSEK---RIPYSEAIQQNFQPC--KVGDSFGPTWWTCWFKVNLKIPETWGGKEVH----LRWESDGEGMVWQNQ-QPVQGLTNEGEKTSYILTECLKD---SESHGITLYVELACNGLFGAGQGSMIAAPDPNRKFTLQKAELVVFNRDVMELLTDFEMLLDMVKVLGEGEQRGFQALFTANEMVNLCDPANPGS----FAAARSLAQKFFAQKNGESQHVVHAMGHCHIDSAWLWPYEETIRKCARSWVTVIRLMEKNPEFVFTCSQAQQFQWVKSWYPGLFSEIKHFIQKGQFIPVGGTWVEMDGNLPSGESMVRQFLHGQNFFKDEFGNYCKEFWLPDTFGYSAQLPQIMKGCGISRFITQKLSWNLINTFPHNTFFWEGIDGTAVLTHFPPGNSYEMKGKVEDLINTVKNNKDKGRANHSALLFGFGDGGGGPTQLMLDRLHRVKDTDCLPKVQMSTPDVLFSHLES-DSSLLCRWVGELFLELHNGTYTTQAKIKMKNRQCETLLHDVEV------ASCLALSKKDSFKYPAC----RLQELWRLLLLNQFHDVIPGSCIGMVVEDALQYYDEIHTTASRLLLDACKSLPSSPDNGIA-----VLNTLSWERTEVISLPMKDTETRLALVRVPSVGVAHVKETAESAESVIATMMVNGTI------------------IMENGLLKATIDHLGRLMSLLLIQ--TNRETISEGCFGNQFALFDDVPLYWDAWDVMDYHLQTRKPV-----IEVIEPAKVLKSGGIQASVS-FSLRINGKSTIQQEIVLDACCPYIKFKTHVVWEEAHKFLKVEFPVQVRSPEATYEIQFGHLQRPTHRNTSWDWARFEVWGHKWADLSEHGFGVALLNDSKYGYSVHQNIMTLSLLRAPKAPDLNADMG--DHIFSYALMPH----TGTFQESAVI-QYAYNFNYPLRVHHG------------VIPKPWSAFSVSSPAIILETIKKAE-----KRENA--LLIRLYESHGSRVTVTLSTSFLLQEVWHCDLL-ERPDFRIPVSETTSGISLTFKPFQIRSLLL 1021
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Zebrafish
Match: man2b2 (mannosidase, alpha, class 2B, member 2 [Source:ZFIN;Acc:ZDB-GENE-140106-166]) HSP 1 Score: 51.6026 bits (122), Expect = 6.489e-6 Identity = 51/209 (24.40%), Postives = 85/209 (40.67%), Query Frame = 3
Query: 864 GGDRLSLHAIGHCHIDTAWLWRFGETRRKLARS-WSTVVGLLDKHPSMAFVCSQAQ--QMDW--LREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSL---VNKFPHHSFIWQG----LDGSRVVTHFPPGDSYSMTCSVPEMLRSA 1454
+++ I H H+D W++ E+ A + +STVV L + + F+ + + ++ W + D+ +R L R +FI +GG V D + + Q G F E FG R W D FG S P + AG + ++ + L + K F+W+G + + TH SY +P RS
Sbjct: 19 AAEKIQAFVIPHSHMDVGWVYTVQESMHAYASNVYSTVVEELTRVKNRKFIAVEQEFFRLWWTNVASDWHKKQVRQLLLEGRLEFI-IGGQ-VMHDEAVTDVDDAILQLTEGHGFLYETFGVRPRFAWHVDPFGASATTPVLFALAGFDAHLISRIDYDLKDDMQKNKKLQFVWRGSPTLKEKQEIFTHTMDQFSYCTPSYIPFSNRSG 225
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Zebrafish
Match: CR352328.2 (mannosidase, alpha, class 2B, member 2 [Source:NCBI gene;Acc:100003570]) HSP 1 Score: 51.2174 bits (121), Expect = 8.900e-6 Identity = 51/209 (24.40%), Postives = 85/209 (40.67%), Query Frame = 3
Query: 864 GGDRLSLHAIGHCHIDTAWLWRFGETRRKLARS-WSTVVGLLDKHPSMAFVCSQAQ--QMDW--LREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSL---VNKFPHHSFIWQG----LDGSRVVTHFPPGDSYSMTCSVPEMLRSA 1454
+++ I H H+D W++ E+ A + +STVV L + + F+ + + ++ W + D+ +R L R +FI +GG V D + + Q G F E FG R W D FG S P + AG + ++ + L + K F+W+G + + TH SY +P RS
Sbjct: 19 AAEKIQAFVIPHSHMDVGWVYTVQESMHAYASNVYSTVVEELTRVKNRKFIAVEQEFFRLWWTNVASDWHKKQVRQLLLEGRLEFI-IGGQ-VMHDEAVTDVDDAILQLTEGHGFLYETFGVRPRFAWHVDPFGASATTPVLFALAGFDAHLISRIDYDLKDDMQKNKKLQFVWRGSPTLKEKQEIFTHTMDQFSYCTPSYIPFSNRSG 225
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Xenopus
Match: man2c1 (mannosidase, alpha, class 2C, member 1 [Source:NCBI gene;Acc:100036651]) HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0 Identity = 406/1126 (36.06%), Postives = 599/1126 (53.20%), Query Frame = 3
Query: 57 KNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSV----LDWCHQVTHSL-------------ASILRMVPPFLINPTSWPLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLIS--NQFFTVAVDSLCRIVRMR-LRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEV------AIDWIKPVMCDCQLKGDNCRQ--FVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
KN RTT ER++KF+S+ YFTD N+ + L I + +T ++S +++++ + A + FG TW WF++ ++P EW + + L W + EA+V G +Q L + + LA + DP + + +Y++ +C+ LFGAG +I D+NK+F L A L + + D +++ D+A+ L +++ +QAL+ ANQ VNM + H I + D FF+ + G + +HA+GHCHID+AWLW + ET RK ARSW + V L+ K+P F CSQAQQ++W++ YP L+ +IK + QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG C EFWLPDTFGYS QLPQ+M GI RF+TQKLSWSL+N FPHH+F W+G+DGS+V+THFPPGDSY M +V E+L++ N+ DKGRV+ +++LYG GDGG GPT+ M+ + R+ + DGLPR+ STPDR++S +E+ + LCTW GELFLELHNGTYTTQ Q+K GN CEQ++ +VE L + + TT + +++ W+L+LLNQFHDVLPG+ I+QV +DA ++ + L + H+L +++ +P S A GL+ +P V + N+ P L N + I+ N +DS R+ + L S+ ES ++ GNQ V++DD+PL+WDAWDVMDYHLET + + S ++ R + TL ENS +EQ + + + +F+T++ W E H+ +KV+ P + + A Y Q G RPTHRNTSWD A+YEV H W+ L E +G+AV + +G SV+ + LSLLRAP SPDATAD H F+YA P +W AG +Q +SF + + +V A + + P + +K +Q V+RL+E G L + P+K ++L ER + L + + L PF + ++++
Sbjct: 21 KNRRTTLERVEKFISEIYFTDCNLRGKLFGATCPLDSISYF--LTEQRISYEEAVKREFQPA------------------QIGQTFGPTWWTCWFKVHVSIPKEWLGEEVH----LRWVCDGEAMVWKD-GEPVQALTNEGQKNSYILAGEFKSHDPQSIT---IYIEVACNGLFGAGQGSMIAPTDLNKTFCLQKAELAIFRRDVQELLLDFQVIYDMAKCLGEDNQRGFQALYVANQMVNMC---DVNDPHTYAIVHKISSD-FFSQRNGVSQHIIHAMGHCHIDSAWLWPYEETIRKCARSWISAVQLMAKYPDFTFTCSQAQQLEWVKNWYPGLYKQIKQYVKLGQFIPVGGTWVEMDGNLPSGESMVRQFLQGQQFFLKEFGKMCTEFWLPDTFGYSAQLPQLMNGCGIHRFLTQKLSWSLINAFPHHTFHWEGIDGSKVLTHFPPGDSYGMMGTVEEVLKTVKNNRDKGRVNDSIFLYGFGDGGGGPTENMVGRIKRMNDTDGLPRVHLSTPDRYFSTVET-DTSQLCTWVGELFLELHNGTYTTQAQIKKGNRQCEQLLHNVEALSAFALAED----------TTFIYPAARLQHLWRLLLLNQFHDVLPGSCIQQVVEDAIGYYKEISTEGLKLLKESIHALLKTCVVETSADHALTVINTLPWERTEVISILGASGQQTLGLVKVP--------------------SMGYVVLPKNLSPATPVTVILQNDNSITMENGILRANIDSAGRLTSLNLLTSNRES---VATGCFGNQFVLFDDIPLYWDAWDVMDYHLETRKLLTSVISKLRISQSGGLRGAVAFTLQIS---ENS--TIEQEIILDASCPYIRFNTKVKWNEAHKFLKVEFPARVRSLNATYEIQFGHIQRPTHRNTSWDWARYEVWAHKWMDLSEHGFGVAVLNDCKYGCSVLKNILSLSLLRAPKSPDATADIGV--HEFSYAFMP----------------------HWG--------TFQEAGVIQSAYSFCAPLLTTELTDVQTKSWSAFNVLSPAIVLETVKQAENQQDSLVLRLYEAYGSSVETWLQTPLPVKEVFSCDLL-ERPSSGKALRLEEQGVKLYFSPFKVLTLLL 1042
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Xenopus
Match: man2c1 (mannosidase, alpha, class 2C, member 1 [Source:NCBI gene;Acc:100036651]) HSP 1 Score: 490.73 bits (1262), Expect = 4.606e-159 Identity = 272/637 (42.70%), Postives = 393/637 (61.70%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSV 1955
+ KN RTT ER++KF+S+ YFTD N+ + L I + +T ++S +++++ + A + FG TW WF++ ++P EW + + L W + EA+V G +Q L + + LA + DP + + +Y++ +C+ LFGAG +I D+NK+F L A L + + D +++ D+A+ L +++ +QAL+ ANQ VNM + H I + D FF+ + G + +HA+GHCHID+AWLW + ET RK ARSW + V L+ K+P F CSQAQQ++W++ YP L+ +IK + QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG C EFWLPDTFGYS QLPQ+M GI RF+TQKLSWSL+N FPHH+F W+G+DGS+V+THFPPGDSY M +V E+L++ N+ DKGRV+ +++LYG GDGG GPT+ M+ + R+ + DGLPR+ STPDR++S +E+ + LCTW GELFLELHNGTYTTQ Q+K GN CEQ++ +VE L + + + TT + +++ W+L+LLNQFHDVLPG+ I+QV +DA ++ +
Sbjct: 1 MLKNRRTTLERVEKFISEIYFTDCNLRGKLFGATCPLDSISYF--LTEQRISYEEAVKREFQPA------------------QIGQTFGPTWWTCWFKVHVSIPKEWLGEEVH----LRWVCDGEAMVWKD-GEPVQALTNEGQKNSYILAGEFKSHDPQSIT---IYIEVACNGLFGAGQGSMIAPTDLNKTFCLQKAELAIFRRDVQELLLDFQVIYDMAKCLGEDNQRGFQALYVANQMVNMC---DVNDPHTYAIVHKISSD-FFSQRNGVSQHIIHAMGHCHIDSAWLWPYEETIRKCARSWISAVQLMAKYPDFTFTCSQAQQLEWVKNWYPGLYKQIKQYVKLGQFIPVGGTWVEMDGNLPSGESMVRQFLQGQQFFLKEFGKMCTEFWLPDTFGYSAQLPQLMNGCGIHRFLTQKLSWSLINAFPHHTFHWEGIDGSKVLTHFPPGDSYGMMGTVEEVLKTVKNNRDKGRVNDSIFLYGFGDGGGGPTENMVGRIKRMNDTDGLPRVHLSTPDRYFSTVET-DTSQLCTWVGELFLELHNGTYTTQAQIKKGNRQCEQLLHNVEALSAFAL----------AEDTTFIYPAARLQHLWRLLLLNQFHDVLPGSCIQQVVEDAIGYYKEI 594
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Xenopus
Match: man2c1 (mannosidase, alpha, class 2C, member 1 [Source:NCBI gene;Acc:100036651]) HSP 1 Score: 491.886 bits (1265), Expect = 1.129e-156 Identity = 279/657 (42.47%), Postives = 402/657 (61.19%), Query Frame = 3
Query: 42 MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRM 2006
M FKN RTT ER++KF+S+ YFTD N+ + L I + +T ++S +++++ + A + FG TW WF++ ++P EW + + L W + EA+V G +Q L + + LA + DP + + +Y++ +C+ LFGAG +I D+NK+F L A L + + D +++ D+A+ L +++ +QAL+ ANQ VNM + H I + D FF+ + G + +HA+GHCHID+AWLW + ET RK ARSW + V L+ K+P F CSQAQQ++W++ YP L+ +IK + QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG C EFWLPDTFGYS QLPQ+M GI RF+TQKLSWSL+N FPHH+F W+G+DGS+V+THFPPGDSY M +V E+L++ N+ DKGRV+ +++LYG GDGG GPT+ M+ + R+ + DGLPR+ STPDR++S +E+ + LCTW GELFLELHNGTYTTQ Q+K GN CEQ++ +VE L + + + TT + +++ W+L+LLNQFHDVLPG+ I+QV +DA ++ D + + S+ S LR+
Sbjct: 1 MILTFKNRRTTLERVEKFISEIYFTDCNLRGKLFGATCPLDSISYF--LTEQRISYEEAVKREFQPA------------------QIGQTFGPTWWTCWFKVHVSIPKEWLGEEVH----LRWVCDGEAMVWKD-GEPVQALTNEGQKNSYILAGEFKSHDPQSIT---IYIEVACNGLFGAGQGSMIAPTDLNKTFCLQKAELAIFRRDVQELLLDFQVIYDMAKCLGEDNQRGFQALYVANQMVNMC---DVNDPHTYAIVHKISSD-FFSQRNGVSQHIIHAMGHCHIDSAWLWPYEETIRKCARSWISAVQLMAKYPDFTFTCSQAQQLEWVKNWYPGLYKQIKQYVKLGQFIPVGGTWVEMDGNLPSGESMVRQFLQGQQFFLKEFGKMCTEFWLPDTFGYSAQLPQLMNGCGIHRFLTQKLSWSLINAFPHHTFHWEGIDGSKVLTHFPPGDSYGMMGTVEEVLKTVKNNRDKGRVNDSIFLYGFGDGGGGPTENMVGRIKRMNDTDGLPRVHLSTPDRYFSTVET-DTSQLCTWVGELFLELHNGTYTTQAQIKKGNRQCEQLLHNVEALSAFAL----------AEDTTFIYPAARLQHLWRLLLLNQFHDVLPGSCIQQVVEDAIGYYK---DTVNNLLTSVISKLRI 611 HSP 2 Score: 120.939 bits (302), Expect = 4.163e-27 Identity = 86/293 (29.35%), Postives = 134/293 (45.73%), Query Frame = 3
Query: 2508 ENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEV------AIDWIKPVMCDCQLKGDNCRQ--FVMRLHEQIGGRFLVRLISSAPIKSAALSNI------LEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
ENS +EQ + + + +F+T++ W E H+ +KV+ P + + A Y Q G RPTHRNTSWD A+YEV H W+ L E +G+AV + +G SV+ + LSLLRAP SPDATAD H F+YA P +W AG +Q +SF + + +V A + + P + +K +Q V+RL+E G L + P+K + ++ L ER + L + + L PF + ++++
Sbjct: 629 ENS--TIEQEIILDASCPYIRFNTKVKWNEAHKFLKVEFPARVRSLNATYEIQFGHIQRPTHRNTSWDWARYEVWAHKWMDLSEHGFGVAVLNDCKYGCSVLKNILSLSLLRAPKSPDATADIGV--HEFSYAFMP----------------------HWG--------TFQEAGVIQSAYSFCAPLLTTELTDVQTKSWSAFNVLSPAIVLETVKQAENQQDSLVLRLYEAYGSSVETWLQTPLPVKEGSSNHKCAPYCDLLERPSSGKALRLEEQGVKLYFSPFKVLTLLL 887
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Xenopus
Match: man2c1 (mannosidase, alpha, class 2C, member 1 [Source:NCBI gene;Acc:100036651]) HSP 1 Score: 489.96 bits (1260), Expect = 1.548e-155 Identity = 277/652 (42.48%), Postives = 399/652 (61.20%), Query Frame = 3
Query: 57 KNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRM 2006
KN RTT ER++KF+S+ YFTD N+ + L I + +T ++S +++++ + A + FG TW WF++ ++P EW + + L W + EA+V G +Q L + + LA + DP + + +Y++ +C+ LFGAG +I D+NK+F L A L + + D +++ D+A+ L +++ +QAL+ ANQ VNM + H I + D FF+ + G + +HA+GHCHID+AWLW + ET RK ARSW + V L+ K+P F CSQAQQ++W++ YP L+ +IK + QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG C EFWLPDTFGYS QLPQ+M GI RF+TQKLSWSL+N FPHH+F W+G+DGS+V+THFPPGDSY M +V E+L++ N+ DKGRV+ +++LYG GDGG GPT+ M+ + R+ + DGLPR+ STPDR++S +E+ + LCTW GELFLELHNGTYTTQ Q+K GN CEQ++ +VE L + + TT + +++ W+L+LLNQFHDVLPG+ I+QV +DA ++ D + + S+ S LR+
Sbjct: 38 KNRRTTLERVEKFISEIYFTDCNLRGKLFGATCPLDSISYF--LTEQRISYEEAVKREFQPA------------------QIGQTFGPTWWTCWFKVHVSIPKEWLGEEVH----LRWVCDGEAMVWKD-GEPVQALTNEGQKNSYILAGEFKSHDPQSIT---IYIEVACNGLFGAGQGSMIAPTDLNKTFCLQKAELAIFRRDVQELLLDFQVIYDMAKCLGEDNQRGFQALYVANQMVNMC---DVNDPHTYAIVHKISSD-FFSQRNGVSQHIIHAMGHCHIDSAWLWPYEETIRKCARSWISAVQLMAKYPDFTFTCSQAQQLEWVKNWYPGLYKQIKQYVKLGQFIPVGGTWVEMDGNLPSGESMVRQFLQGQQFFLKEFGKMCTEFWLPDTFGYSAQLPQLMNGCGIHRFLTQKLSWSLINAFPHHTFHWEGIDGSKVLTHFPPGDSYGMMGTVEEVLKTVKNNRDKGRVNDSIFLYGFGDGGGGPTENMVGRIKRMNDTDGLPRVHLSTPDRYFSTVET-DTSQLCTWVGELFLELHNGTYTTQAQIKKGNRQCEQLLHNVEALSAFALAED----------TTFIYPAARLQHLWRLLLLNQFHDVLPGSCIQQVVEDAIGYYK---DTVNNLLTSVISKLRI 643 HSP 2 Score: 121.324 bits (303), Expect = 3.877e-27 Identity = 86/293 (29.35%), Postives = 134/293 (45.73%), Query Frame = 3
Query: 2508 ENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEV------AIDWIKPVMCDCQLKGDNCRQ--FVMRLHEQIGGRFLVRLISSAPIKSAALSNI------LEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
ENS +EQ + + + +F+T++ W E H+ +KV+ P + + A Y Q G RPTHRNTSWD A+YEV H W+ L E +G+AV + +G SV+ + LSLLRAP SPDATAD H F+YA P +W AG +Q +SF + + +V A + + P + +K +Q V+RL+E G L + P+K + ++ L ER + L + + L PF + ++++
Sbjct: 661 ENS--TIEQEIILDASCPYIRFNTKVKWNEAHKFLKVEFPARVRSLNATYEIQFGHIQRPTHRNTSWDWARYEVWAHKWMDLSEHGFGVAVLNDCKYGCSVLKNILSLSLLRAPKSPDATADIGV--HEFSYAFMP----------------------HWG--------TFQEAGVIQSAYSFCAPLLTTELTDVQTKSWSAFNVLSPAIVLETVKQAENQQDSLVLRLYEAYGSSVETWLQTPLPVKEGSSNHKCAPYCDLLERPSSGKALRLEEQGVKLYFSPFKVLTLLL 919
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Xenopus
Match: man2c1 (mannosidase, alpha, class 2C, member 1 [Source:NCBI gene;Acc:100036651]) HSP 1 Score: 489.189 bits (1258), Expect = 1.639e-155 Identity = 277/652 (42.48%), Postives = 400/652 (61.35%), Query Frame = 3
Query: 57 KNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRM 2006
KN RTT ER++KF+S+ YFTD N+ + L I + +T ++S +++++ + A + FG TW WF++ ++P EW + + L W + EA+V G +Q L + + LA + DP + + +Y++ +C+ LFGAG +I D+NK+F L A L + + D +++ D+A+ L +++ +QAL+ ANQ VNM + H I + D FF+ + G + +HA+GHCHID+AWLW + ET RK ARSW + V L+ K+P F CSQAQQ++W++ YP L+ +IK + QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG C EFWLPDTFGYS QLPQ+M GI RF+TQKLSWSL+N FPHH+F W+G+DGS+V+THFPPGDSY M +V E+L++ N+ DKGRV+ +++LYG GDGG GPT+ M+ + R+ + DGLPR+ STPDR++S +E+ + LCTW GELFLELHNGTYTTQ Q+K GN CEQ++ +VE L + + + TT + +++ W+L+LLNQFHDVLPG+ I+QV +DA ++ D + + S+ S LR+
Sbjct: 11 KNRRTTLERVEKFISEIYFTDCNLRGKLFGATCPLDSISYF--LTEQRISYEEAVKREFQPA------------------QIGQTFGPTWWTCWFKVHVSIPKEWLGEEVH----LRWVCDGEAMVWKD-GEPVQALTNEGQKNSYILAGEFKSHDPQSIT---IYIEVACNGLFGAGQGSMIAPTDLNKTFCLQKAELAIFRRDVQELLLDFQVIYDMAKCLGEDNQRGFQALYVANQMVNMC---DVNDPHTYAIVHKISSD-FFSQRNGVSQHIIHAMGHCHIDSAWLWPYEETIRKCARSWISAVQLMAKYPDFTFTCSQAQQLEWVKNWYPGLYKQIKQYVKLGQFIPVGGTWVEMDGNLPSGESMVRQFLQGQQFFLKEFGKMCTEFWLPDTFGYSAQLPQLMNGCGIHRFLTQKLSWSLINAFPHHTFHWEGIDGSKVLTHFPPGDSYGMMGTVEEVLKTVKNNRDKGRVNDSIFLYGFGDGGGGPTENMVGRIKRMNDTDGLPRVHLSTPDRYFSTVET-DTSQLCTWVGELFLELHNGTYTTQAQIKKGNRQCEQLLHNVEALSAFAL----------AEDTTFIYPAARLQHLWRLLLLNQFHDVLPGSCIQQVVEDAIGYYK---DTVNNLLTSVISKLRI 616 HSP 2 Score: 120.168 bits (300), Expect = 6.751e-27 Identity = 87/285 (30.53%), Postives = 136/285 (47.72%), Query Frame = 3
Query: 2508 ENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNI------LEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
ENS +EQ + + + +F+T++ W E H+ +KV+ P + + A Y Q G RPTHRNTSWD A+YEV H W+ L E +G+AV + +G SV+ + LSLLRAP SPDATAD H F+YA P T A + + A F C L+ +Q ++ SP+ + ++ +K V + Q V+RL+E G L + P+K + ++ L ER + L + + L PF + ++++
Sbjct: 634 ENS--TIEQEIILDASCPYIRFNTKVKWNEAHKFLKVEFPARVRSLNATYEIQFGHIQRPTHRNTSWDWARYEVWAHKWMDLSEHGFGVAVLNDCKYGCSVLKNILSLSLLRAPKSPDATADIGV--HEFSYAFMPHWGTFQE-----AGVIQSAYSF---CA----PLLTTELTDVQTKSWSAFNVLSPA---IVLETVKQVSAENQQDS-----LVLRLYEAYGSSVETWLQTPLPVKEGSSNHKCAPYCDLLERPSSGKALRLEEQGVKLYFSPFKVLTLLL 894
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Mouse
Match: Man2c1 (mannosidase, alpha, class 2C, member 1 [Source:MGI Symbol;Acc:MGI:1920994]) HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0 Identity = 421/1117 (37.69%), Postives = 590/1117 (52.82%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSWPLAVQNSAAGLLVIP-PCXXXXXXXXXXXX---XXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQ---FVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W + L W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L + ++ DL+LLL +A+ L +S+ ++QALH ANQ VN + + + A+ +FF G + ++HA+GHCHIDTAWLW F ET RK ARSWST V L++++ F CSQAQQ++W++ YP L R++ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM+ GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ TN+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + ++ LE + LCTW GELFLELHNGTYTT QLK GN CEQ++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V +DA + + + + + A+ L P +IN W +L +P PC + + A Q + V V + D L N V +D + + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P I +P+A Y Q G RPTH NTSWD A+YEV H WI L E ++G+A+ +G+SV G + LSLLRAP +PDATAD H F YAL P F + +N N L + G S+ SP+ V ++ IK + + C Q V+RL+E G L +S P++ A L ++LE+R T G+L + L PF + S+++
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCSVT-----------------------LSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGQEVH----LCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLRASDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHSLLVDLELLLGVAKGLGEDSQRSFQALHTANQMVN----ICDPAQPETYPAAKALASKFFGQHGGESQHTIHAMGHCHIDTAWLWPFKETVRKCARSWSTAVTLMEQNTDFIFACSQAQQLEWVKSQYPGLHARLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPGQLFTALER-DSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVEVLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNPLLSAAAAALCAGEPGPKGLLIINTLPW------KRTEVLALPKPCGAHSLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTL---DNGIIRVRLDPTGCLTSLVLVA--SGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARIRSPQATYEIQFGHLQRPTHNNTSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGASVRGNVLSLSLLRAPKAPDATADMGR--HEFTYALMPHK-------GSFQEAGVIHAAYNLNF----PLLALPAPGPAPDTTWSAFSVSSPA---VVLETIK--------QAERCHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPT-GHLSLQDNRLKLTFSPFQVRSLLL 1032
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Mouse
Match: Man2c1 (mannosidase, alpha, class 2C, member 1 [Source:MGI Symbol;Acc:MGI:1920994]) HSP 1 Score: 627.861 bits (1618), Expect = 0.000e+0 Identity = 419/1117 (37.51%), Postives = 588/1117 (52.64%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSWPLAVQNSAAGLLVIP-PCXXXXXXXXXXXX---XXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQ---FVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W + L W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L + ++ DL+LLL +A+ L +S+ ++QALH ANQ VN + + + A+ +FF G + ++HA+GHCHIDTAWLW F ET RK ARSWST V L++++ F CSQAQQ++W++ YP L R++ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM+ GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ TN+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + ++ LE + LCTW GELFLELHNGTYTT Q GN CEQ++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V +DA + + + + + A+ L P +IN W +L +P PC + + A Q + V V + D L N V +D + + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P I +P+A Y Q G RPTH NTSWD A+YEV H WI L E ++G+A+ +G+SV G + LSLLRAP +PDATAD H F YAL P F + +N N L + G S+ SP+ V ++ IK + + C Q V+RL+E G L +S P++ A L ++LE+R T G+L + L PF + S+++
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCSVT-----------------------LSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGQEVH----LCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLRASDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHSLLVDLELLLGVAKGLGEDSQRSFQALHTANQMVN----ICDPAQPETYPAAKALASKFFGQHGGESQHTIHAMGHCHIDTAWLWPFKETVRKCARSWSTAVTLMEQNTDFIFACSQAQQLEWVKSQYPGLHARLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPGQLFTALER-DSGQLCTWVGELFLELHNGTYTTHAQ--KGNRECEQILHDVEVLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNPLLSAAAAALCAGEPGPKGLLIINTLPW------KRTEVLALPKPCGAHSLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTL---DNGIIRVRLDPTGCLTSLVLVA--SGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARIRSPQATYEIQFGHLQRPTHNNTSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGASVRGNVLSLSLLRAPKAPDATADMGR--HEFTYALMPHK-------GSFQEAGVIHAAYNLNF----PLLALPAPGPAPDTTWSAFSVSSPA---VVLETIK--------QAERCHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPT-GHLSLQDNRLKLTFSPFQVRSLLL 1030
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Mouse
Match: Man2c1 (mannosidase, alpha, class 2C, member 1 [Source:MGI Symbol;Acc:MGI:1920994]) HSP 1 Score: 514.612 bits (1324), Expect = 8.859e-166 Identity = 343/926 (37.04%), Postives = 480/926 (51.84%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDT-----------------------------------------AWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSWPLAVQNSAAGLLVIP-PCXXXXXXXXXXXX---XXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQY 2657
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W + L W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L + ++ DL+LLL +A+ L +S+ ++QALH ANQ VN+ + + A+ +FF G + ++HA+GHCHIDT AWLW F ET RK ARSWST V L++++ F CSQAQQ++W++ YP L R++ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM+ GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ TN+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + ++ LE + LCTW GELFLELHNGTYTT QLK GN CEQ++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V +DA + + + + + A+ L P +IN W +L +P PC + + A Q + V V + D L N V +D + + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P I +P+A Y
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCSVTL-----------------------SSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGQEVH----LCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLRASDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHSLLVDLELLLGVAKGLGEDSQRSFQALHTANQMVNI----CDPAQPETYPAAKALASKFFGQHGGESQHTIHAMGHCHIDTGVSRCTSKCVFFSQLLAVLIQMQLRFLTMEQGLMKLDLRPRAWLWPFKETVRKCARSWSTAVTLMEQNTDFIFACSQAQQLEWVKSQYPGLHARLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPGQLFTALER-DSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVEVLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNPLLSAAAAALCAGEPGPKGLLIINTLPW------KRTEVLALPKPCGAHSLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTL---DNGIIRVRLDPTGCLTSLVLVA--SGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARIRSPQATY 866
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Mouse
Match: Man2c1 (mannosidase, alpha, class 2C, member 1 [Source:MGI Symbol;Acc:MGI:1920994]) HSP 1 Score: 471.47 bits (1212), Expect = 1.477e-148 Identity = 306/789 (38.78%), Postives = 427/789 (54.12%), Query Frame = 3
Query: 1017 SQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSWPLAVQNSAAGLLVIP-PCXXXXXXXXXXXX---XXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQ---FVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
++AQQ++W++ YP L R++ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM+ GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ TN+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + ++ LE + LCTW GELFLELHNGTYTT QLK GN CEQ++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V +DA + + + + + A+ L P +IN W +L +P PC + + A Q + V V + D L N V +D + + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P I +P+A Y Q G RPTH NTSWD A+YEV H WI L E ++G+A+ +G+SV G + LSLLRAP +PDATAD H F YAL P + F + +N N L + G S+ SP+ V ++ IK + + C Q V+RL+E G L +S P++ A L ++LE+R T G+L + L PF + S+++
Sbjct: 198 AKAQQLEWVKSQYPGLHARLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPGQLFTALER-DSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVEVLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNPLLSAAAAALCAGEPGPKGLLIINTLPW------KRTEVLALPKPCGAHSLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTL---DNGIIRVRLDPTGCLTSLVLVA--SGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARIRSPQATYEIQFGHLQRPTHNNTSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGASVRGNVLSLSLLRAPKAPDATADMGR--HEFTYALMPHKGS-------FQEAGVIHAAYNLNF----PLLALPAPGPAPDTTWSAFSVSSPA---VVLETIK--------QAERCHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPT-GHLSLQDNRLKLTFSPFQVRSLLL 933 HSP 2 Score: 90.5077 bits (223), Expect = 7.506e-18 Identity = 77/246 (31.30%), Postives = 113/246 (45.93%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEA--LPNSETAYQALHAANQ 767
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W + L W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L + ++ DL+LLL +A+A L ++ Y LHA Q
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCSVT-----------------------LSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGQEVH----LCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLRASDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHSLLVDLELLLGVAKAQQLEWVKSQYPGLHARLQ 218
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Mouse
Match: Man2c1 (mannosidase, alpha, class 2C, member 1 [Source:MGI Symbol;Acc:MGI:1920994]) HSP 1 Score: 90.1225 bits (222), Expect = 8.421e-20 Identity = 64/207 (30.92%), Postives = 93/207 (44.93%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQL 656
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W + L W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L +
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCSVT-----------------------LSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGQEVH----LCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLRASDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAV 179
BLAST of Alpha-mannosidase 2C1 vs. UniProt/SwissProt
Match: sp|Q91W89|MA2C1_MOUSE (Alpha-mannosidase 2C1 OS=Mus musculus OX=10090 GN=Man2c1 PE=1 SV=1) HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0 Identity = 421/1117 (37.69%), Postives = 590/1117 (52.82%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSWPLAVQNSAAGLLVIP-PCXXXXXXXXXXXX---XXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQ---FVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W + L W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L + ++ DL+LLL +A+ L +S+ ++QALH ANQ VN + + + A+ +FF G + ++HA+GHCHIDTAWLW F ET RK ARSWST V L++++ F CSQAQQ++W++ YP L R++ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM+ GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ TN+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + ++ LE + LCTW GELFLELHNGTYTT QLK GN CEQ++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V +DA + + + + + A+ L P +IN W +L +P PC + + A Q + V V + D L N V +D + + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P I +P+A Y Q G RPTH NTSWD A+YEV H WI L E ++G+A+ +G+SV G + LSLLRAP +PDATAD H F YAL P F + +N N L + G S+ SP+ V ++ IK + + C Q V+RL+E G L +S P++ A L ++LE+R T G+L + L PF + S+++
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCSVT-----------------------LSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVWVGQEVH----LCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLRASDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHSLLVDLELLLGVAKGLGEDSQRSFQALHTANQMVN----ICDPAQPETYPAAKALASKFFGQHGGESQHTIHAMGHCHIDTAWLWPFKETVRKCARSWSTAVTLMEQNTDFIFACSQAQQLEWVKSQYPGLHARLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPGQLFTALER-DSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVEVLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNPLLSAAAAALCAGEPGPKGLLIINTLPW------KRTEVLALPKPCGAHSLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTL---DNGIIRVRLDPTGCLTSLVLVA--SGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARIRSPQATYEIQFGHLQRPTHNNTSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGASVRGNVLSLSLLRAPKAPDATADMGR--HEFTYALMPHK-------GSFQEAGVIHAAYNLNF----PLLALPAPGPAPDTTWSAFSVSSPA---VVLETIK--------QAERCHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPT-GHLSLQDNRLKLTFSPFQVRSLLL 1032
BLAST of Alpha-mannosidase 2C1 vs. UniProt/SwissProt
Match: sp|Q9NTJ4|MA2C1_HUMAN (Alpha-mannosidase 2C1 OS=Homo sapiens OX=9606 GN=MAN2C1 PE=1 SV=1) HSP 1 Score: 608.216 bits (1567), Expect = 0.000e+0 Identity = 405/1109 (36.52%), Postives = 581/1109 (52.39%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPP-----FLINPTSW--------PLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPF 3323
A K+WRTT ER++KF+S YFTD N+ + + + +T +L +++++ + A + FG TW WFR+E +P W + L W S+ E LV G +QGL +T+ L + DP + + LYV+ +C+ L GAG +I APD K F+L A L + + DL+LLL IA+ L +++ ++QAL+ ANQ VN+ + + A+ RFF G + ++HA GHCHIDTAWLW F ET RK ARSW T + L++++P F CSQAQQ++W++ YP L+ RI+ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM GI RF+TQKLSW+LVN FPHH+F W+GLDGSRV+ HFPPGDSY M SV E+L++ N+ DKGR + + +L+G GDGG GPT ML L R++N DGLPR+ S+P + +S LES + + LCTW GELFLELHNGTYTT Q+K GN CE+++ VE+L S+ + + + Q++ W+L+LLNQFHDV+ G+ I+ V ++A + + + + + A+ L P ++N W P + L+ +P A + ++ + V D V +D N V +D R+ + L + I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + + +A Y Q G RPTH NTSWD A++EV H W+ L E +G+A+ + +G+SV G + LSLLRAP +PDATAD H F YAL P + + A + + A N+ L + S+ SP+ V ++ +K Q R V+RL+E G L S P++ A L ++L ER G+L + L PF
Sbjct: 4 APALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLS--SFLTPERLPYQEAVQRDFRPA------------------QVGDSFGPTWWTCWFRVELTIPEAWVGQEVH----LCWESDGEGLVWRD-GEPVQGLTKEGEKTSYVLTDRLGERDPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAVFHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNV----CDPAQPETFPVAQALASRFFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQAQQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLSNTDGLPRVQLSSPRQLFSALES-DSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERILHDVELLSSLAL----------ARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIRSHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLALVTVPSMGYAPVPPPTSLQPLLPQQPVFVVQETDGSVTLD-------------NGIIRVKLDPTGRLTSLVLVA--SGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGR--HEFTYALMPHKGSFQD-----AGVIQAAYSLNFP------LLALPAPSPAPATSWSAFSVSSPA---VVLETVKQAESSPQR-----RSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLL-ERPDPAGHLTLRDNRLKLTFSPF 1026
BLAST of Alpha-mannosidase 2C1 vs. UniProt/SwissProt
Match: sp|P21139|MA2C1_RAT (Alpha-mannosidase 2C1 OS=Rattus norvegicus OX=10116 GN=Man2c1 PE=1 SV=1) HSP 1 Score: 473.011 bits (1216), Expect = 3.459e-147 Identity = 279/636 (43.87%), Postives = 377/636 (59.28%), Query Frame = 3
Query: 45 ASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDSENFTPELH--WNSECEALVVNSHGNIIQGLNATHSRTAVSLAA-IEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDA 1934
A K+WRTT ER++KF+S YFTD N+ + D +T S+ PE L + + A FG TW WFR+E +P W E+H W S+ E+LV G +QGL +T+ L+ + DP + + LYV+ +C+ L GAG +I APD K F+L A+L + + DL+LLL +A+ L +++ ++QAL+ ANQ VN + + + A +FF + G + ++HA GHCHIDTAWLW F ET RK ARSWST V L++++ F CSQAQQ++W++ YP L+ +++ R QF+PVGGTWVEMD NLP E++ RQFL GQNF+ + FG C EFWLPDTFGYS QLPQIM+ GI RF+TQKLSW+LVN FPHH+F W+GLDGS+V+ HFPPGDSY M SV E+L++ TN+ DKGR + + +L+G GDGG GPT ML L R+ N DG PR+ S+P + ++ LE + LCTW GELFLELHNGTYTT QLK GN CEQ++ VE+L S+ + SA + Q +L+LLNQFHDV+ G+ I+ V +DA
Sbjct: 4 APFLKHWRTTFERVEKFVSPIYFTDCNLRGRLFGDSCPVT-----------------------LSSFLTPERLPYEKAVQQNFSPAQVGDSFGPTWWTCWFRVELVIPEVW------VGKEVHLCWESDGESLVWRD-GEPVQGLTKEGEKTSYVLSERLHAADPRSLT---LYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHNLLVDLELLLGVAKGLGEDNQRSFQALYTANQMVN----ICDPAQPETYPAAEALASKFFGQRGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWSTAVKLMERNTEFTFACSQAQQLEWVKNQYPGLYAQLQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSQVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLGNTDGQPRVQLSSPGQLFTALER-DSGQLCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVELLSSLAL--------ARSAQFLYPAVQLQRLW--RLLLLNQFHDVVTGSCIQLVAEDA 591 HSP 2 Score: 166.392 bits (420), Expect = 2.260e-40 Identity = 111/345 (32.17%), Postives = 165/345 (47.83%), Query Frame = 3
Query: 2313 ISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
I+ GNQ V++DDVPL+WDAWDVMDYHLET + Q + V E + S + +S + + Q + + + +F T + W E H+ +KV+ P + +P+A Y Q G + SWD A+YEV H WI L E ++G+A+ +G+SV G + LSLLRAP +PD TAD H F YAL P + F + +N N L + G S+ SP+ V ++ IK K R V+RL+E G L +S P++ A L ++LE+R T G+L + L PF + S+++
Sbjct: 717 IAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVRGQAGTLAVGAEGGLRGSAWFLLQISP------NSRLSQEVVLDVGCPYVRFHTEVHWHETHKFLKVEFPARVRSPQATYEIQFGHLQEADPQQHSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGTSVRGNVLSLSLLRAPKAPDVTADMGR--HEFTYALMPHKGS-------FQEAGVIQAAYNLNF----PLLALPAPGPAPDTTWSAFSVSSPA---VVLETIKQAE-----KSHQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPT-GHLSLQDNRLKLTFSPFQVRSLLL 1033
BLAST of Alpha-mannosidase 2C1 vs. UniProt/SwissProt
Match: sp|Q54K67|MANG_DICDI (Alpha-mannosidase G OS=Dictyostelium discoideum OX=44689 GN=manG PE=1 SV=1) HSP 1 Score: 432.95 bits (1112), Expect = 9.510e-132 Identity = 260/657 (39.57%), Postives = 370/657 (56.32%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPK---LSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGL-NATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPN-SETAYQALHAANQTVNM--LVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQ-VTHSLASI 1997
+ K+ T ERI+KFLSD YF N+ +I+ L E +K+ +PK +S KD+++L K KI E FG +W+ +WF++ +VPT+W+ + +F WNS CE L+ +G IQGL T IE + H Y++ SC+ +FG G +GLIN D +++F+L A +++ + A+ + L++L D+ + P S QA+ AN +N + D T S +L K FF+ + + A+GHCHID WLW F +T+ K ARS+ST + +D +P F SQAQ W +E+YP+L+ RIK QFIP GGTWVEMD NLP ES RQFLYGQ F+++ FG C EF+LPDTFGYS QLPQ++R GI F+TQKLSW+ +NKFPH +FIW+G+DGS V+THFPP D+Y+ V E++ S++N+ D R + +M LYG+GDGG GPT M+ L + + G+P+I STP +F+ LE + L W GEL+ ELH GTYT+Q K GN CE + + EML S + + + + K W+ +LL QFHD LPG+SI+ +D H+ VL C +T S+ I
Sbjct: 7 MLKHQDVTIERIEKFLSDTYFVRENLYGKLIS----LKSSEAVKVKVSPKVEGISYKDAIQLEYKDT-KIGES-----------------FGPSWTNYWFKVTIDVPTDWKDKTIHFI----WNSSCEGLIW-MNGIAIQGLIGGTWQDLREEYKLIE--NSKGGEHFEFYIEISCNGMFGVGKDGLINPCDPDRTFELTKAEIRVKNKEANELYMYLQMLYDVGKNFPKESLRKKQAIWVANDIINQCNVNDSRTFSKCIELAKKE-----FFSQHNSESQTRVWAVGHCHIDLCWLWSFEKTKEKCARSFSTQILYMDYYPQFKFTQSQAQAYQWTKENYPELYERIKEKVVTGQFIPTGGTWVEMDGNLPSGESFIRQFLYGQRFFEKEFGKKCTEFFLPDTFGYSAQLPQVIRHMGIENFITQKLSWNNLNKFPHSTFIWEGIDGSSVLTHFPPADTYNSQADVKEIVMSSSNNKDIDRCNESMLLYGNGDGGGGPTIPMIERLTILKDTAGIPKIEFSTPAQFFKQLEP-HRSKLNKWVGELYFELHRGTYTSQATTKRGNRLCEIELHATEMLTSYCELFVEGFKSPN------------LSKLWQQVLLCQFHDALPGSSIQVCYEDILKIHQQVLVECKNIITQSMNHI 616 HSP 2 Score: 157.532 bits (397), Expect = 1.286e-37 Identity = 113/350 (32.29%), Postives = 171/350 (48.86%), Query Frame = 3
Query: 2220 LISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGS-GNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISS---APIKSAALSNILEE 3257
LI NQF ++ + S RI + +S + +I GS GN+L+++DD LFWDAWD + LE I + + ++ + + R V SK GL + V Q++ V S F T ++W E H++++V T I A A Y Q G RPTH NTSWD A++EV GH W L E ++G+A+ + +G S +GG + LSLLR+P SPD T D H F Y+++P +R ++ S + ++ N + I + L + S + + +D IK K ++ FV+R++E GG SS P KS N LEE
Sbjct: 735 LIDNQFISIVIGSNGRIKSLIEKS--ANREVIKQDGSLGNRLIIFDDTCLFWDAWDQEIFSLEKPLSILE-GTCKIIENGPL-RCVVQVHYDSK-GLPSGNGSVNQTIIVHFNSARVDFETNVNWNEAHKLLRVDFDTNIRAKNANYEIQFGHIERPTHYNTSWDFARFEVVGHKWADLSEYDFGMALLNDCKYGYSTLGGRIGLSLLRSPKSPDDTCDMG--SHKFTYSIYP---------HRGSLQSASVIKEGYSL--NNNFYISETPFSLASTTHIDKTFISTNKEAIIVDTIK--------KAEDGTSFVVRVYESFGGATTFNFTSSILPIPFKSIIECNGLEE 1058
BLAST of Alpha-mannosidase 2C1 vs. UniProt/SwissProt
Match: sp|Q9UT61|MAN1_SCHPO (Alpha-mannosidase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ams1 PE=3 SV=1) HSP 1 Score: 376.326 bits (965), Expect = 6.220e-111 Identity = 233/647 (36.01%), Postives = 343/647 (53.01%), Query Frame = 3
Query: 81 RIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLE--LFDKSALKIPEVLSMDGNQW-------ETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALP-NSETAYQALHAANQTVNML--VDMTTDSMHQKLIKA--RHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDR---VANFDG-LPRIT-HSTPDRFYSDL--ESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTIL--------EQIEKQWKLILLNQFHDVLPGTSIEQVCDDA 1934
R+D+FLS+ + D N+ + +H +I NP + L D ++P++ N+ ET K + FG +W+ WF + +P W K + WN + E LV + G +Q + + RT L D + Y++ +C+ +FG G I PD N+ F L A L ++ A + D L+ + LP N Y+A N +N D++T + + L KA + +D + D+ ++ AIGHCHIDTAWLW F ETRRK+ RSW+T + ++D++P FVCSQA Q WL+ED+PD+F ++K + +FIP+GG+WVE D N+P ESL RQFL GQ+F+++ FG CR FWLPDTFGYS Q+PQI R G+ RF+TQKLSW+ +N FP +F W LDGS+V+ H PP ++Y+ +V ++L S H + + ++G GDGG GPT EML L R +AN G LP + +T D F+ + + L +W+GEL+ E H GTYTTQ +LK ++MR VE+ + ++T+ +I E ++ W+ LL QFHDVLPG+ IE V DA
Sbjct: 23 RLDQFLSEGQYRDFNLPSVY----------DHARI-DNPSGDVNNDLSKGFVDLKVYRVPDLSRPSFNEVVGHKKFDETASKGD-TFGPSWATFWFEVHIRLPKSWAKYEQVI---FQWNCDNEGLVYSQDGVPLQAFSGSE-RTDFILP-----DSWKTTEDTFYIEMACNGMFGTGAGSQIAPPDPNRYFTLTKADLVAPNLPAMALAYDFLLMQQCVKQLPSNCWQKYKARQICNDIMNTFHPNDLSTINECRNLAKAFLGNDIDSEAVFEKNNDKANVFAIGHCHIDTAWLWPFAETRRKIVRSWATQMNIMDRYPEYQFVCSQALQYLWLKEDHPDVFEKLKEYVNQNKFIPIGGSWVEHDTNIPNGESLIRQFLLGQHFFEKEFGVRCRTFWLPDTFGYSSQIPQICRLCGMDRFLTQKLSWNNINSFPTSTFNWVALDGSQVICHMPPANTYTADTNVNDVLHSIDQHKNLVNDQAGLLVFGIGDGGGGPTPEMLEKLRRCKGIANTVGYLPNVKLGNTVDEFFDGILKRTNAGQTLPSWNGELYFEFHRGTYTTQAELK-------KLMRKVEIAL-----------HDAEYVSTLASIFSKDYSYPKESLQDLWRDTLLCQFHDVLPGSCIEMVYKDA 630 HSP 2 Score: 128.257 bits (321), Expect = 1.416e-28 Identity = 103/352 (29.26%), Postives = 154/352 (43.75%), Query Frame = 3
Query: 2319 NVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALF----PFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRL-ISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCP-----FAIASIIV 3344
N NQ V+++D PL W AWD + LE +D+ +E+ R++ V + TI + F+ +DW E + +KV+ P I++ A Y TQ G RPTH NTSWD AK+EVC + + +G++V + +G S G + LSLLR+P PDA AD H YA++ P D + ++F RL T+ + D+ +D Q V G P+ V + IK + + ++R++E +GG+ RL I S + S N LEE L CT +S D P F IA+ V
Sbjct: 757 NHAGANQYVLFEDTPLSWQAWDTEVFSLEKYEVLDKGKV--SIKESGPLRASVVVDIPISELSHMKATISLEGYNDCSEFTGVNFTCEVDWHESCKFLKVEFPVDIHSEFASYETQFGITKRPTHYNTSWDVAKFEVCHQKFADYSDFTYGVSVLNDCKYGFSTHGNLMRLSLLRSPKQPDAHADMG--KHTIRYAVYPHSKPLDSSTVRAAHKFNSNFRLLTRAS-------DTANLDIFDAFQLV-------GEPN---VILSHIK--------MAEKGKSIILRVYESLGGKSRARLVIKSLTVASVTKCNGLEEDLEE----LCTLKSNDYYEVPIELRAFEIATFKV 1075
BLAST of Alpha-mannosidase 2C1 vs. TrEMBL
Match: K1QJL8 (Alpha-mannosidase 2C1 OS=Crassostrea gigas OX=29159 GN=CGI_10021044 PE=4 SV=1) HSP 1 Score: 700.279 bits (1806), Expect = 0.000e+0 Identity = 419/1120 (37.41%), Postives = 618/1120 (55.18%), Query Frame = 3
Query: 54 FKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELH--WNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEAL-PNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTH-SLASILRMVPPFLINPTSWPLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLH-------------LISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGS--GNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERL--VTNGNLCCTPESIDLLMCPFAIASIIVEF 3350
K+ RTT ER DKF+S YF D N+ + D L I H + ++P ++ G +T + FG TWS HWF+LE +P + + E+H WNS EALV GN IQGL+ + R + L+ + N++ LYV+ +C+ + G G + +I PDMNK+F L A + + + D++ L D+A+ + +E YQAL+ NQ +NML D+ + + KA +FF + G + +L+A+GH H+D+AWLW + ET RK ARSWS + L++++P F CSQAQQ +W++++YP L+ +IK ++ +FIPVGGTWVEMD N+P E+ RQFLYGQ F+ + F C EFWLPDTFGYSPQLPQIM+ GISRF+TQKLSWSLVNKFPHH+F W+G+DGSRV++HFPPGDSY M V E+LR+ N+ DKGR + ++YL+G GDGG GP+++ML + R+ + DGLP++ TP F+SD+E + NLC W GEL+LELHNGTYTT ++K N CE + VE L S+ + + + T E++ + WKL+LLNQFHDVLPGTSI V +DA+ + ++ C +++ +LASI+ + Q++ +++ T + P +V +D Q ++L ++ N++ + +D+L RI+ + L E N IS+ GNQ VMYDD+PL+WDAWDVMDYHLET + Q+ R V+LV + + + +I +Q +++ S + +F T++DW E + +KV+ PT +++ A Y Q G H R H NTSWD A++EV GH W + E N+G+AV ++ +G S G + LSLLR+P SPD AD H F YA+ PF T + A + + A + N N + D ++ +Q+ SF S+ +P +V ++ IK D ++RL+E GG+ V+L + P S N LEE L +L I L PF I S++++F
Sbjct: 17 LKHKRTTLERADKFISPVYFNDVNLRGRLYRDNHPLKSITHY------------------AAPGRVPYQQAVKGKFTKT--EIGQSFGPTWSTHWFQLEIEIPDNMKGE------EVHLLWNSNSEALVWQG-GNPIQGLSGDYDRISFPLSKVLGK---NKTRCSLYVEMACNRILGEGKDSMIGPPDMNKTFTLSQAEIAVFDREVYELIIDIETLHDMAKHMTEETERGYQALYTMNQMINML-DLDDRATYS---KAHQLAKKFFQQRNGQSQHTLYAMGHAHMDSAWLWPYAETVRKCARSWSCTIRLMEQYPHFTFTCSQAQQYEWVKDNYPGLYTQIKEFVKKGRFIPVGGTWVEMDGNIPSGEAFVRQFLYGQRFFMKEFNKKCSEFWLPDTFGYSPQLPQIMKLFGISRFLTQKLSWSLVNKFPHHTFWWEGIDGSRVLSHFPPGDSYEMHGKVEEVLRTIKNYKDKGRSNKSVYLFGFGDGGNGPSEDMLVRMSRLQDVDGLPKVQPKTPQDFFSDVEKEDCGNLCRWRGELYLELHNGTYTTHAKVKKMNRFCEFRLHDVEFLASMAHIQSLIKKAAYKFPT------EELHRLWKLLLLNQFHDVLPGTSIGLVYEDAHQYYDDIVASCQKLSSDALASII-------------ADSAQSNPVSMVINCMGWHRKEVVTMSQSTGTPAKKQKKSP---ELVQIDSQGNTLVKCEKPCSIEKKQNGTFILHNEYLSAEIDNLGRIITLTLNG--EERNAISSEPGCYGNQFVMYDDIPLYWDAWDVMDYHLETRKPVLLSTKKTTIQDQGPLR----VSLVVEIKISDRSSI-KQVISLDTGSPYLRFQTQVDWHENRKFLKVEFPTSVHSMSATYEIQFGHHQRTNHNNTSWDWAQFEVFGHKWAAISEHNFGVAVLNDSKYGYSTRDGVMRLSLLRSPKSPDKDADMG--THSFTYAVMPFQGTFQS-----AGVIQAAYELN-NPL---DVHTLNLPKGVQESKSF-FSVDNP---QVILETIKK-------SEDLDNALILRLYESYGGQAKVKLTADLPFTSVKRCNGLEEILDNEVTSDLEVIGRQITLSFKPFEIISLLLKF 1051
BLAST of Alpha-mannosidase 2C1 vs. TrEMBL
Match: A0A267GET6 (Alpha-mann_mid domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006850g1 PE=4 SV=1) HSP 1 Score: 696.041 bits (1795), Expect = 0.000e+0 Identity = 447/1141 (39.18%), Postives = 621/1141 (54.43%), Query Frame = 3
Query: 42 MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEW-------EKDSENFTPELH--WNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDD------PLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLG---------GDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCH------QVTHSLASILRMVPPFLINPTSWPLAV---QNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGN-------QLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQ-VFQEAAVTRSNHSVTLV---SKFGLENSGT-------IVEQSLTVTERSEFCQFSTRID-WREKHRMVKVKVP-TVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVF-LSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLAT--QFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNG---EVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGR--------FLVRLISSAPIKSAALSNILEERL 3263
+ + K+WRTT ERI+KF+S YF D+N+ ++ I+HLK S + DK L + WE ID F FG WSIHWFR++ +W K S + E+H WNS+ EAL+ + G IIQG+ + H T + A + PDD P N S +LY+Q S S+LFGAG + + PD + L +L S + +DL LL++IA+ L ++ ++AL+ N VN+ + D A D FF + G DR+ LHA+GHCHIDTAWLW + ETRRK ARSWS+ + L+ KHP M FV SQAQQ+DWL+ DYP+LF I +L ++ +F+PVGG WVEMD NLPCCESL RQF YGQ F++ HFG C EFWLPDTFGYS QLPQ+MR AG+S F+TQKLSWSLVNKFPHHSF+W+G+DGS V+ HFPPGDSY+M E+ SA+NH DKGR A +LYGHGDGGQGP +ML L+R+++ GLPR++H TP ++ LES + NL +W+GEL+LELHNGTYTT R +KLGN CE +R VE L+++ G T V L+ ++ W L+LLNQFHDVLPG+SI +V D+ + +L C +V+ AS+ L+NPT W +++ ++ L+ +PP ++ Q+ +++ P + + ++ N+ +DS R+V + I ++G+G QL Y D+PLFWDAWD+MDY ET + + A+ + E+ S+HS V + + + T I Q + ER F TR+ WR H +++V++P V A QAG RPT NTSWD A +E C H ++ L EAN+G+A K+AI+G SV G+V LSLLR+P PDA AD H YAL P A + + + S +AT QF + L + + S ++ P+ G V +DWIKPV D + F++RL+E +GG +L R + + +A SN LEE+L
Sbjct: 2 LQDVHKHWRTTYERIEKFISPHYFCDSNLLSRQTSNRAAALSIQHLK-------SQEFLGSWLDKKTLTTESL-------WEDID-LGFKFGPVWSIHWFRVQLP-KADWLEEAFAASKQSGSINSEVHFQWNSDTEALIFSPTGRIIQGVTSLHDGTRET-AELSPDDQNDLQSPFNESQLMLYLQCSVSELFGAGPS-CVRPPDPKRQGNLSKCQLIRRDPIISRLIQDLHLLMEIAKELKETDQGHRALYCGNSIVNLCLQCRYDD-------AIKLADEFFKASRGTTMEPAGTSKDRMLLHAMGHCHIDTAWLWDYAETRRKTARSWSSTLRLMRKHPKMTFVVSQAQQLDWLKTDYPNLFSEIVSLAKQDRFLPVGGCWVEMDTNLPCCESLLRQFHYGQKFFQRHFGRKCPEFWLPDTFGYSGQLPQLMRHAGMSWFLTQKLSWSLVNKFPHHSFVWRGIDGSEVLAHFPPGDSYNMQVLPSELAFSASNHRDKGRTQHAGFLYGHGDGGQGPGPDMLDRLERLSDCPGLPRLSHGTPRTLFTGLES-DRANLHSWTGELYLELHNGTYTTHRSIKLGNFRCESALRVVEFLLAL----------GVLDETATVESLDSLDTAWHLLLLNQFHDVLPGSSIGRVYADSARHYNQILSVCSRFRSMDEVSTPAASVSEFA---LVNPTQWSMSLTLPEDHGRRLVSLPP---------------LSVCRLDQLLLKEATPPEPTAKLLDSKVVVLENEHLKAEIDSFGRVVSL----------ISKSIGAGRECLLAPVQLTYYHDMPLFWDAWDIMDYSWETRATVAEDATGKGRLIESCRIDSSHSCQTVYELTSYPTSSDATDSNLVSRIEHQVALLPERPHCLTFCTRVTPWRAAHTLLRVELPCNVRGVTRASAEIQAGRVDRPTRGNTSWDWAAHEHCSHRYLDLSEANFGLATIKQAIYGGSVRDGSVVNLSLLRSPRGPDAEADFNS-EHCLRYALMPHQSLA-GLTDSSSCRSLVATACQFGYQSDVELTRLRLTDRTAVPLTTSPLVTFEQPAPGSSQSVVLDWIKPVR-----SVDKSKWFLVRLYESVGGFVPNCCLRIYLPR--TGGRLTAAFESNALEEQL 1069
BLAST of Alpha-mannosidase 2C1 vs. TrEMBL
Match: A0A1I8H2F9 (Alpha-mann_mid domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0 Identity = 447/1141 (39.18%), Postives = 621/1141 (54.43%), Query Frame = 3
Query: 42 MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEW-------EKDSENFTPELH--WNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDD------PLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLG---------GDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCH------QVTHSLASILRMVPPFLINPTSWPLAV---QNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGN-------QLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQ-VFQEAAVTRSNHSVTLV---SKFGLENSGT-------IVEQSLTVTERSEFCQFSTRID-WREKHRMVKVKVP-TVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVF-LSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLAT--QFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNG---EVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGR--------FLVRLISSAPIKSAALSNILEERL 3263
+ + K+WRTT ERI+KF+S YF D+N+ ++ I+HLK S + DK L + WE ID F FG WSIHWFR++ +W K S + E+H WNS+ EAL+ + G IIQG+ + H T + A + PDD P N S +LY+Q S S+LFGAG + + PD + L +L S + +DL LL++IA+ L ++ ++AL+ N VN+ + D A D FF + G DR+ LHA+GHCHIDTAWLW + ETRRK ARSWS+ + L+ KHP M FV SQAQQ+DWL+ DYP+LF I +L ++ +F+PVGG WVEMD NLPCCESL RQF YGQ F++ HFG C EFWLPDTFGYS QLPQ+MR AG+S F+TQKLSWSLVNKFPHHSF+W+G+DGS V+ HFPPGDSY+M E+ SA+NH DKGR A +LYGHGDGGQGP +ML L+R+++ GLPR++H TP ++ LES + NL +W+GEL+LELHNGTYTT R +KLGN CE +R VE L+++ G T V L+ ++ W L+LLNQFHDVLPG+SI +V D+ + +L C +V+ AS+ L+NPT W +++ ++ L+ +PP ++ Q+ +++ P + + ++ N+ +DS R+V + I ++G+G QL Y D+PLFWDAWD+MDY ET + + A+ + E+ S+HS V + + + T I Q + ER F TR+ WR H +++V++P V A QAG RPT NTSWD A +E C H ++ L EAN+G+A K+AI+G SV G+V LSLLR+P PDA AD H YAL P A + + + S +AT QF + L + + S ++ P+ G V +DWIKPV D + F++RL+E +GG +L R + + +A SN LEE+L
Sbjct: 3 LQDVHKHWRTTYERIEKFISPHYFCDSNLLSRQTSNRAAALSIQHLK-------SQEFLGSWLDKKTLTTESL-------WEDID-LGFKFGPVWSIHWFRVQLP-KADWLEEAFAASKQSGSINSEVHFQWNSDTEALIFSPTGRIIQGVTSLHDGTRET-AELSPDDQNDLQSPFNESQLMLYLQCSVSELFGAGPS-CVRPPDPKRQGNLSKCQLIRRDPIISRLIQDLHLLMEIAKELKETDQGHRALYCGNSIVNLCLQCRYDD-------AIKLADEFFKASRGTTMEPAGTSKDRMLLHAMGHCHIDTAWLWDYAETRRKTARSWSSTLRLMRKHPKMTFVVSQAQQLDWLKTDYPNLFSEIVSLAKQDRFLPVGGCWVEMDTNLPCCESLLRQFHYGQKFFQRHFGRKCPEFWLPDTFGYSGQLPQLMRHAGMSWFLTQKLSWSLVNKFPHHSFVWRGIDGSEVLAHFPPGDSYNMQVLPSELAFSASNHRDKGRTQHAGFLYGHGDGGQGPGPDMLDRLERLSDCPGLPRLSHGTPRTLFTGLES-DRANLHSWTGELYLELHNGTYTTHRSIKLGNFRCESALRVVEFLLAL----------GVLDETATVESLDSLDTAWHLLLLNQFHDVLPGSSIGRVYADSARHYNQILSVCSRFRSMDEVSTPAASVSEFA---LVNPTQWSMSLTLPEDHGRRLVSLPP---------------LSVCRLDQLLLKEATPPEPTAKLLDSKVVVLENEHLKAEIDSFGRVVSL----------ISKSIGAGRECLLAPVQLTYYHDMPLFWDAWDIMDYSWETRATVAEDATGKGRLIESCRIDSSHSCQTVYELTSYPTSSDATDSNLVSRIEHQVALLPERPHCLTFCTRVTPWRAAHTLLRVELPCNVRGVTRASAEIQAGRVDRPTRGNTSWDWAAHEHCSHRYLDLSEANFGLATIKQAIYGGSVRDGSVVNLSLLRSPRGPDAEADFNS-EHCLRYALMPHQSLA-GLTDSSSCRSLVATACQFGYQSDVELTRLRLTDRTAVPLTTSPLVTFEQPAPGSSQSVVLDWIKPVR-----SVDQSKWFLVRLYESVGGFVPNCCLRIYLPR--TGGRLTAAFESNALEEQL 1070
BLAST of Alpha-mannosidase 2C1 vs. TrEMBL
Match: A0A267GEQ0 (Alpha-mann_mid domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012546g8 PE=4 SV=1) HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0 Identity = 447/1135 (39.38%), Postives = 617/1135 (54.36%), Query Frame = 3
Query: 57 KNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEF------NVPTEWEKDSENFTPELH--WNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDD------PLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLG---------GDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCH------QVTHSLASILRMVPPFLINPTSWPLAV---QNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGN-------QLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQ-VFQEAAVTRSNHSVTLV---SKFGLENSGT-------IVEQSLTVTERSEFCQFSTRID-WREKHRMVKVKVP-TVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVF-LSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLAT--QFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNG---EVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGR--------FLVRLISSAPIKSAALSNILEERL 3263
K+WRTT ERI+KF+S YF D+N+ ++ I+HLK S + DK L + WE ID F FG WSIHWFR++ N K S + E+H WNS+ EAL+ + G IIQG+ + H T + A + PDD P N S +LY+Q S S+LFGAG + + PD + L +L S + +DL LL++IA+ L ++ ++AL+ N VN+ + D A D FF + G DR+ LHA+GHCHIDTAWLW + ETRRK ARSWS+ + L+ KHP M FV SQAQQ+DWL+ DYP+LF I +L ++ +F+PVGG WVEMD NLPCCESL RQF YGQ F++ HFG C EFWLPDTFGYS QLPQ+MR AG+S F+TQKLSWSLVNKFPHHSF+W+G+DGS V+ HFPPGDSY+M E+ SA+NH DKGR A +LYGHGDGGQGP +ML L+R+++ GLPR++H TP ++ LES + NL +W+GEL+LELHNGTYTT R +KLGN CE +R VE L+++ G T V L+ ++ W L+LLNQFHDVLPG+SI +V D+ + +L C +V+ AS+ + L+NPT W +++ ++ L+ +PP ++ Q+ +++ P + + ++ N+ +DS R+V + I ++G+G QL Y D+PLFWDAWD+MDY ET + + A+ + E S HS V + + + T I Q + ER F TR+ WR H +++V++P V A QAG RPT NTSWD A +E C H ++ L EAN+G+A K+AI+G SV G+V LSLLR+P PDA AD H YAL P A + + + S +AT QF + L + + S ++ P+ G V +DWIKPV D + F++RL+E +GG +L R + + +A SN LEE+L
Sbjct: 5 KHWRTTYERIEKFISPLYFCDSNLLSRQTSNRAAALSIQHLK-------SQEFLGSWLDKKTLTTESL-------WEDID-LGFKFGPVWSIHWFRVQLPKADWLNEAFAASKKSGSINSEVHFQWNSDTEALIFSPTGRIIQGVTSLHDGTRET-AELSPDDQNDLQSPFNESQLMLYLQCSVSELFGAGPS-CVRPPDPKRQGNLSKCQLIRRDPIISRLIQDLHLLMEIAKELKETDQGHRALYCGNSIVNLCLQCRYDD-------AIKLADEFFKASRGTTMEPAGTSKDRMLLHAMGHCHIDTAWLWDYAETRRKTARSWSSTLRLMRKHPKMTFVVSQAQQLDWLKTDYPNLFSEIVSLAKQDRFLPVGGCWVEMDTNLPCCESLLRQFHYGQKFFQRHFGRKCPEFWLPDTFGYSGQLPQLMRHAGMSWFLTQKLSWSLVNKFPHHSFVWRGIDGSEVLAHFPPGDSYNMQVLPSELAFSASNHRDKGRTQHAGFLYGHGDGGQGPGPDMLDRLERLSDCPGLPRLSHGTPRTLFTGLES-DRANLHSWTGELYLELHNGTYTTHRSIKLGNFRCESALRVVEFLLAL----------GVLDETATVESLDSLDTAWHLLLLNQFHDVLPGSSIGRVYADSARHYNQILSVCSRFRSMDEVSTPAASVSELA---LVNPTQWSMSLTLPEDHGRRLVSLPP---------------LSVCRLDQLLLKEATPPEPTAKLLDSKVVVLENEHLKAEIDSFGRVVSL----------ISKSIGAGRECLLAPVQLTYYHDMPLFWDAWDIMDYSWETRATVAEDATGKGRLIEPCRIDSPHSCKTVYELTSYPTSSDATDSNLVSRIEHQVALLPERPHCLTFCTRVTPWRAAHTLLRVELPCNVRGVTRANAEIQAGRVDRPTRGNTSWDWAAHEHCSHRYLDLSEANFGLATIKQAIYGGSVRDGSVVNLSLLRSPRGPDAEADFNS-EHCLRYALMPHQGLA-GLTDSSSCRSLVATACQFGYQSDVELTRLRLTDRTAVPLTTSPLVTFEQPAPGSSQSVVLDWIKPVR-----SVDQSKWFLVRLYESVGGFVPNCCLRIYLPR--TGGRLTAAFESNALEEQL 1067
BLAST of Alpha-mannosidase 2C1 vs. TrEMBL
Match: A0A0P5AFG8 (Alpha-mannosidase 2C1 OS=Daphnia magna OX=35525 PE=4 SV=1) HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0 Identity = 418/1128 (37.06%), Postives = 614/1128 (54.43%), Query Frame = 3
Query: 42 MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNAT--HSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSE-----TAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASIL------RMVPPFLINPTSWP----LAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVT-RSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNC--VWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNC--RQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLL---MCPFAIASIIVEF 3350
MASL KN RTT ERI+KF+S YFTD N+ I ++ I H + N T E+ ++ P L FG T++ HWF++ +P W + L WNS EAL+ N+ G+ +QG + H + + + + + Y++ +C+ +FGAG G+I+APD++K + L A + + A + DL+LL ++A+ L + + YQAL+A NQ VN + D ++ A+ + FF + G + A+GHCHIDTAWLW + ET RK ARSW++V+ L+ +P M FVCSQAQQ W+++ YP L+ IK + +FIPVGGTWVEMD N+P ES RQFLYGQ F+ + FG +EFWLPDTFGYS Q PQI+R GISRF+TQKLSWSLVN+FPHH+F+W+GLDGS V+ HFPP DSY +C V E L++ N DKGRV+ ++ LYG+GDGG GP ML ++R+ + DG+P++ +STP++F+ +LE+ + LC W GEL+LELHNGTYT+Q +K N CE +R E+L+++ + + VV + I++ W+L+L+NQFHDVLPG+SIE V +A R L +V + L ++ P IN W + + + + P S V V PV D ++ I+NQ+F+V +DS RI+ M H +I GNQLV++DD+PL+WDAWD MDYH+ET +++ +S + +E V ++ VTL + + V Q + +T F QF TR++W E + +KV+ P ++A +A + TQ GF SRP H+NTSWD+AK+EVCGH W L E WG+AV ++ +G SV G + +SLLR+P +PDA D H F YAL P + +RF VI +N+NC + + I +G V S + ++ +KP C+ L ++ ++ ++RL E G R R+ ++ P+ L N LEE + +L + E PF + S ++ F
Sbjct: 40 MASLHKNRRTTLERIEKFVSRVYFTDVNLYGRIYPQ-QDNVDIFHWPLPQNKHWKTISFDEVVKQTF--TPVCLGS-------------CFGPTFATHWFKVVVKIPESWSGKEIH----LRWNSSSEALLFNTLGDPLQGFTGSPDHQKREEFIISKSWERKETEQELVYYIEMACNSMFGAGKGGMIDAPDLDKKYALEMANIAVCDTVAYRLLIDLELLFEMAKELTDVDGKGDSRGYQALYAGNQIVNAI---QADDWNE----AQRISNDFFKHRNGQRAHVIDAMGHCHIDTAWLWPYDETIRKCARSWASVIALMKDYPEMTFVCSQAQQFSWVKQHYPSLYKEIKHFIDLGRFIPVGGTWVEMDGNIPSGESFIRQFLYGQRFFIKEFGMRSQEFWLPDTFGYSAQTPQILRHVGISRFLTQKLSWSLVNRFPHHNFLWEGLDGSTVLVHFPPADSYEASCKVSEALKTERNLLDKGRVTKSIMLYGYGDGGGGPHKPMLDRMERLKDVDGVPKLMNSTPNKFFENLEAES-SQLCRWVGELYLELHNGTYTSQADMKKFNRCCEYKLRDAELLLAVSLALDRI------PLVDVVGLRTNIDEAWRLLLVNQFHDVLPGSSIELVHTEAKQWFRKCLRLAEEVAERCIAYLQGKANQQLTTPSFINTLPWSRNAIIYEEEKPVRAVNVQPMSWC-------------------VKELGGVTPV--VIDKTGGIYKIANQWFSVEIDSCGRIISM--IHHASGNQVIPAESFGNQLVLFDDIPLYWDAWDCMDYHIETRNVVNRPSSTE--EEVHVELQTPLKVTLKWSQSV-GKQSRVHQKIHITAVDCFVQFETRVEWSENRKFLKVEFPVEVHANQASFDTQFGFLSRPNHKNTSWDSAKFEVCGHKWADLSEPTWGVAVLNDSKYGWSVHGKTITMSLLRSPKAPDANCDMH--EHFFRYALMPHH----GLKSRFDVIKE---SYNFNCEMISTKSVNDISVSGSWFTVDS----------SSIVLETVKP--CEPMLNSEDAPVKKILLRLFESCGDRTQARIETNLPLLDYTLCNGLEEPIGPTSSLAASAEGKKFFTASFTPFQVKSFLLSF 1086
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Cavefish
Match: man2c1 (mannosidase alpha class 2C member 1 [Source:NCBI gene;Acc:103023374]) HSP 1 Score: 633.639 bits (1633), Expect = 0.000e+0 Identity = 414/1113 (37.20%), Postives = 594/1113 (53.37%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSET-AYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPPFLINPTSWPLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHL---------ISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSG-TIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIVEF 3350
+ KN RT ER +KF+SD YFTD N+ + D L +S+ +F ++A +IP ++ N K FG TW WF++ +P W+ + L W S+ E +V +QGL +T+ L + ++P + + L+V+ +C+ LFGAG +I APD N+ + L A L + + + D ++LLDI + L E YQAL N+ VN+ + KAR +FF+ K G + +HA+GHCHID+AWLW + ET RK ARSW T V L++K+P F CSQAQQ W+++ YP LF +I+ ++ QF+PVGGTWVEMD NLP ES+ RQFL GQNF+K FG +C+EFWLPDTFGYS QLPQ+M+ +GISRF+TQKLSW+LVN FPH++F W+G++GS V+THFPPG+SY M V +++ + N+ DKGR + + L+G GDGG GPT ML L RV + DGLPR+ S PDR +S+L++ + LCTWSGELFLELHNGTYTTQ ++KL N CE ++ +E+ + + E E+++K W+L+LLNQFHDV+PG+ IE V +DA + + + HS + LR P W L +S A L +P T D T+ + P V PV +S++ + + + N + +D++ R+V + L + IS+ GNQ V++DDVPL+WDAWDVMDYHL+T I D +V + S KF L+ SG + + Q + + + +F T++DW E H+ +KV+ P + +P A Y Q G RPTHRNTSWD A++EV GH W L E +G+A+ + +G SV + LSLLRAP +PDA AD H F YA+ P AVI A N+ D + P S + + V ++ +K Q +G V+RL+E G L +S ++ A ++L ER T T I L PF I S++++
Sbjct: 6 VLKNRRTLLERGEKFISDVYFTDCNLRGRLYGDTCPL-----------------ESITVF-QTAKRIPYSEAVQQNFQPC--KVGDSFGPTWWTCWFKIALKIPEAWKGKEVH----LRWESDGEGMVWRDQ-EPVQGLTKEGEKTSYILTECLTENEPYSIT---LFVELACNGLFGAGQGSMIAAPDPNRKYTLQKAELVVFNSEVQELLTDFEMLLDIVKLLGEGEQRGYQALFTMNEMVNLCDPANPGTWS----KARSLAQKFFSQKNGESQHIVHAMGHCHIDSAWLWPYEETIRKCARSWVTAVRLMEKNPEFIFTCSQAQQFQWVKDWYPGLFSQIQHFVQKGQFVPVGGTWVEMDGNLPSGESMVRQFLEGQNFFKAEFGQYCKEFWLPDTFGYSAQLPQLMQGSGISRFLTQKLSWNLVNTFPHNTFFWEGINGSLVLTHFPPGNSYEMKGRVEDLINTLKNNKDKGRANHSAVLFGFGDGGGGPTQLMLDRLQRVQDSDGLPRVHMSNPDRLFSELQA-DSSLLCTWSGELFLELHNGTYTTQAKIKLENRRCEALLHDIEVASCLALTQTAGFEYPT----------EKLQKLWRLLLLNQFHDVIPGSCIEIVVEDALEYYNEIEKTGSGLLHSACNALRTSP--------W-LGAGSSPAFLNTLP--WERTEVIALTEDGAQTKLALVKAP-SVGVSPVTASAESVSTVSITELADGSVRMENGLLSAVLDNMGRLVSLILVQ--TNREAISDGCFGNQFVVFDDVPLYWDAWDVMDYHLQTRKPIVDVTRPVEVVSTGGLRGS-------VKFSLQISGKSSITQEVILDANCPYIKFKTKVDWAEAHKFLKVEFPVQVRSPNATYEIQFGHLQRPTHRNTSWDWARFEVWGHKWADLSEHGFGVALLNDCKYGYSVYQNIMTLSLLRAPKAPDANADMGQ--HEFTYAVMPH----AGSFQEAAVIQH-AYNLNFPLRLIHDVKVAQ-----------PWSAFTLNTSAVILETVK------QAEGKK-NALVVRLYESHGSSVSAVLSTSLSVQEAWYCDLL-ERPDTAHPASFTGSKISLTFKPFQIISLLLQL 1028
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Cavefish
Match: man2c1 (mannosidase alpha class 2C member 1 [Source:NCBI gene;Acc:103023374]) HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0 Identity = 391/1117 (35.00%), Postives = 562/1117 (50.31%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSET-AYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVP-------PFLINPTSW------PLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI-DQIASFQVFQEAAVTRSNHSVTLVSKFGLENSG-TIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIVEF 3350
+ KN RT ER +KF+SD YFTD N+ + D L +S+ +F ++A +IP ++ N K FG TW WF++ +P W+ + L W S+ E +V +QGL +T+ L + ++P + + L+V+ +C+ LFGAG +I APD N+ + L A L + + + D ++LLDI + L E YQAL N+ VN+ + KAR +FF+ K G + +HA+GHCHID+AWLW + ET RK ARSW T V L++K+P F CSQ I + +L + D NLP ES+ RQFL GQNF+K FG +C+EFWLPDTFGYS QLPQ+M+ +GISRF+TQKLSW+LVN FPH++F W+G++GS V+THFPPG+SY M V +++ + N+ DKGR + + L+G GDGG GPT ML L RV + DGLPR+ S PDR +S+L++ + LCTWSGELFLELHNGTYTTQ ++KL N CE ++ +E+ + + E E+++K W+L+LLNQFHDV+PG+ IE V +DA + + + HS + LR P P +N W L + L++ P R + Q D + N + +D++ R+V + L + IS+ GNQ V++DDVPL+WDAWDVMDYHL+T I D +V + S KF L+ SG + + Q + + + +F T++DW E H+ +KV+ P + +P A Y Q G RPTHRNTSWD A++EV GH W L E +G+A+ + +G SV + LSLLRAP +PDA AD H F YA+ P AVI A N+ D + P S + + V ++ +K Q +G V+RL+E G L +S ++ A ++L ER T T I L PF I S++++
Sbjct: 6 VLKNRRTLLERGEKFISDVYFTDCNLRGRLYGDTCPL-----------------ESITVF-QTAKRIPYSEAVQQNFQPC--KVGDSFGPTWWTCWFKIALKIPEAWKGKEVH----LRWESDGEGMVWRDQ-EPVQGLTKEGEKTSYILTECLTENEPYSIT---LFVELACNGLFGAGQGSMIAAPDPNRKYTLQKAELVVFNSEVQELLTDFEMLLDIVKLLGEGEQRGYQALFTMNEMVNLCDPANPGTWS----KARSLAQKFFSQKNGESQHIVHAMGHCHIDSAWLWPYEETIRKCARSWVTAVRLMEKNPEFIFTCSQNMMQS----------ISLISLSQ--------------DGNLPSGESMVRQFLEGQNFFKAEFGQYCKEFWLPDTFGYSAQLPQLMQGSGISRFLTQKLSWNLVNTFPHNTFFWEGINGSLVLTHFPPGNSYEMKGRVEDLINTLKNNKDKGRANHSAVLFGFGDGGGGPTQLMLDRLQRVQDSDGLPRVHMSNPDRLFSELQA-DSSLLCTWSGELFLELHNGTYTTQAKIKLENRRCEALLHDIEVASCLALTQTAGFEYPT----------EKLQKLWRLLLLNQFHDVIPGSCIEIVVEDALEYYNEIEKTGSGLLHSACNALRTSPWLGAGSSPAFLNTLPWERTEVIALTEDGAQTKLVLFSPTHQ-----------------------RSEAWLSELQADGSVRME---NGLLSAVLDNMGRLVSLILVQ--TNREAISDGCFGNQFVVFDDVPLYWDAWDVMDYHLQTRKPIVDVTRPVEVVSTGGLRGS-------VKFSLQISGKSSITQEVILDANCPYIKFKTKVDWAEAHKFLKVEFPVQVRSPNATYEIQFGHLQRPTHRNTSWDWARFEVWGHKWADLSEHGFGVALLNDCKYGYSVYQNIMTLSLLRAPKAPDANADMGQ--HEFTYAVMPH----AGSFQEAAVIQH-AYNLNFPLRLIHDVKVAQ-----------PWSAFTLNTSAVILETVK------QAEGKK-NALVVRLYESHGSSVSAVLSTSLSVQEAWYCDLL-ERPDTAHPASFTGSKISLTFKPFQIISLLLQL 994
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Cavefish
Match: man2a1 (mannosidase alpha class 2A member 1 [Source:NCBI gene;Acc:103023301]) HSP 1 Score: 52.7582 bits (125), Expect = 2.907e-6 Identity = 52/223 (23.32%), Postives = 87/223 (39.01%), Query Frame = 3
Query: 876 LSLHAIGHCHIDTAWLWRFGETRRKLARSW--STVVGLLDKH------PSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFI-------WQGLDGSRVVTHFPPGDSYSM--TCSVPEML--RSATNHADKGRVSC 1487
L + + H H D WL F + R + + VV LL+ +++ +D + D +K L ER Q G WV D ++ Q L G + +++ G R W D FG+S I++QAG+S + Q++ +S+ F + W + ++ H P SY + TC + + GR+SC
Sbjct: 166 LHVVVVPHSHNDPGWLKTFDDYFRDQTQHILNNMVVKLLEDVRRKMIWSEISYFAKWWDNIDSQKRD------SVKKLIERGQLEIATGGWVMPDEANSHYSAMIDQLLEGHQWLEKNVGVKPRTGWAVDPFGHSSTQAYILKQAGLSNMLIQRVHYSIKKHFSTQKTLEFFWRQNWDHDSSTDILCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISC 382
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Cavefish
Match: man2a1 (mannosidase alpha class 2A member 1 [Source:NCBI gene;Acc:103023301]) HSP 1 Score: 52.373 bits (124), Expect = 2.993e-6 Identity = 52/223 (23.32%), Postives = 87/223 (39.01%), Query Frame = 3
Query: 876 LSLHAIGHCHIDTAWLWRFGETRRKLARSW--STVVGLLDKH------PSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFI-------WQGLDGSRVVTHFPPGDSYSM--TCSVPEML--RSATNHADKGRVSC 1487
L + + H H D WL F + R + + VV LL+ +++ +D + D +K L ER Q G WV D ++ Q L G + +++ G R W D FG+S I++QAG+S + Q++ +S+ F + W + ++ H P SY + TC + + GR+SC
Sbjct: 166 LHVVVVPHSHNDPGWLKTFDDYFRDQTQHILNNMVVKLLEDVRRKMIWSEISYFAKWWDNIDSQKRD------SVKKLIERGQLEIATGGWVMPDEANSHYSAMIDQLLEGHQWLEKNVGVKPRTGWAVDPFGHSSTQAYILKQAGLSNMLIQRVHYSIKKHFSTQKTLEFFWRQNWDHDSSTDILCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRISC 382
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005606.1 (pep scaffold:Pmarinus_7.0:GL490907:1909:6217:-1 gene:ENSPMAG00000005089.1 transcript:ENSPMAT00000005606.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 245.743 bits (626), Expect = 1.987e-72 Identity = 153/433 (35.33%), Postives = 208/433 (48.04%), Query Frame = 3
Query: 60 NWRTTSERIDKFLSDKYFTDANITKIIIADVKELT--KIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANF--VFGKTWSIHWFRLEFNVPTEWEKDS-------ENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNS-------ETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYP-DLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRF 1301
N RT ERI+K LS YFTD N+ + D + ++ + H ++S +D+ Q T ++ +G TWS HWF++ VP EW S E L W E E L+ G + GL +T+ + S YV+ +C+ LFGAG +I PD + F L A + L + DL+++ ++A L + Y+AL+ N + D D G +HA+GHCHIDTAWLW + ET RK ARSW+T + L+D+ P FVCSQAQQ+ WL++ Y L+ R++A R F+PVGGTWVE D NLP ESL RQFL GQ F+ FGA C EFWLPDTFGYS QLPQI+ + +F
Sbjct: 1 NKRTALERIEKALSPLYFTDVNLRGRLYEDARPVSGLAVHH----AGGRISFQDA--------------------QSATYERTQVGDSYGPTWSTHWFQVHVEVPEEWTCKSGDDDDDDECDEVHLLWECEGECLLFRD-GQPVAGLTTEGEKTSYVVG--RARRRTPPSSSSSYVEMACNGLFGAGGGSMIAPPDPERKFALKRAAVALFRRDVYELLTDLEVIYEVACGLAGEADGRGGEQLGYRALYCGNAVASACADAPRPGPAGAAPAGDDSGD-----TPGCRGTVVHAMGHCHIDTAWLWPYEETVRKCARSWATALQLMDRDPEFTFVCSQAQQLSWLKQRYSCSLYPRVRAAVARGAFVPVGGTWVEFDGNLPSGESLVRQFLLGQRFFLHEFGARCDEFWLPDTFGYSAQLPQIVNHFQLHKF 401
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004199.1 (pep scaffold:Pmarinus_7.0:GL486244:117:1844:1 gene:ENSPMAG00000003833.1 transcript:ENSPMAT00000004199.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 176.407 bits (446), Expect = 1.253e-47 Identity = 130/401 (32.42%), Postives = 188/401 (46.88%), Query Frame = 3
Query: 1842 EQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSV-LDWCHQVTHSLASILRMVPPFLINPTSWPLAVQNSAA---------------GL-LVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIAS-FQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVI--NAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFN 2984
+Q+ + W+ +LLNQFHDVLPG+ QV DA + V +D ++A++++ P P P+A N+ GL LV P + + + A + V + ++ DS A ++ N V+VD R+ L P ++ NQLVM+DDVPL+WDAWDVMDYHLET ++ + +V AA R +V G + T+ +++ S F +F W E R +K + P + + EA Y Q G RPTHRNTSWD +YEV H W HLGE +G+A+ + +G S G + LSLLR+P +PD AD H F YA P + N A + R A+ FN
Sbjct: 4 QQLTRLWEGVLLNQFHDVLPGSCTRQVARDAEEIYGGVEIDAGQIARDAMAAVVQREPGVRDFPRD-PIAFFNTLGWERTEVAALPGRGVNGLVLVTVPAFGYSVYSEASLLASAA---------KSLAVILHHESDSRA---VLENDLLRVSVDGAGRLTS--LIHKPSGREAVTPGQKANQLVMFDDVPLYWDAWDVMDYHLETRKPQERTSEPLRVLTNAAGIRV--AVRACLHLGERSRATV---DISLDAGSPFVRFDVTAAWHENRRFLKTEFPVAVRSSGGEATYEIQFGHVRRPTHRNTSWDWPRYEVWAHRWAHLGEHGFGLALLNDCKYGHSARGNVLSLSLLRSPKAPDPEADMGE--HTFAYAAMPHQGSFQN-----AGVIRCASAFN 377
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006368.1 (pep scaffold:Pmarinus_7.0:GL478975:152485:159376:1 gene:ENSPMAG00000005752.1 transcript:ENSPMAT00000006368.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 48.1358 bits (113), Expect = 7.412e-6 Identity = 26/100 (26.00%), Postives = 47/100 (47.00%), Query Frame = 3
Query: 1074 IKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHH---SFIWQ 1364
++ L ER Q V G WV D ++ Q + G + + G R W D FG+SP + ++R+AG+ + Q++ +++ H F+W+
Sbjct: 199 VRRLVERGQLEFVTGGWVMTDEANAHYFAIIDQMIEGHQWLHKTLGVRPRSGWAIDPFGHSPTMAYVLRRAGLQAMLIQRVHYAVKRHLAHERSLEFMWR 298
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003432.1 (pep scaffold:Pmarinus_7.0:GL488094:1155:3927:-1 gene:ENSPMAG00000003140.1 transcript:ENSPMAT00000003432.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 47.7506 bits (112), Expect = 9.754e-6 Identity = 27/90 (30.00%), Postives = 39/90 (43.33%), Query Frame = 3
Query: 1077 KALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPH 1346
K L + Q V G WV D ++ Q L G + + H G R W D FG+SP ++R AGI + Q+ +S+ H
Sbjct: 195 KRLIDGGQLEIVTGGWVMPDEANVHVWAMLDQMLEGHQWLERHLGVRPRSGWAIDPFGHSPTNAYLLRAAGIQNMLIQRTHYSVKKHLAH 284
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Yeast
Match: AMS1 (Vacuolar alpha mannosidase; involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway [Source:SGD;Acc:S000003124]) HSP 1 Score: 336.65 bits (862), Expect = 1.447e-98 Identity = 209/557 (37.52%), Postives = 306/557 (54.94%), Query Frame = 3
Query: 303 NFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALP-NSETAYQALHAANQTVNMLVDMTTDSMHQ-KLIKARHFLDRFFAS----KLGGDRL--SLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIK-ALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDG-----LPRITHS-TPDRFYSDL--ESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQV 1922
N FG +WS WF+++ ++P +W K +E W+ E +V++ I + RT L + Y++A + +FG G IN PD N+ F L A + + A + D +L D A LP +S +QA N +N+ S+ + + + R + D F S + G ++ +++ IG+CHIDTAWLW F ETRRK+ RSWS+ L+D+ P FV SQAQQ WL ED+P+ F ++ ++ QF VGGTWVE D N+P ESL RQF +GQ F+ +HFG + FWLPDTFGYS Q+PQ+ R +GI +F+TQKLSW+ +N FPH +F W G+DGS+++TH PPG++Y+ ++LR+A + + LYG GDGG GPT+EML + R+ + + +P++ T D FY D+ + +L TWSGEL+ E H GTYT+Q Q K E + +E + + V S + S +QI + W+ +LL QFHDVLPG+ IE V
Sbjct: 98 NQPFGPSWSTTWFKVKISLPEDWVKSNEQLL--FQWDCSNEGIVIDPKTLIPVTAFSGGERTEYVLPKT------SDGKHFFYIEAGNNGMFGCGAGSTINPPDDNRFFHLRKADIVWPDLDARALYIDFWMLGDAARELPGDSWQKHQARQLGNAVMNLFDPNDRSSVRKCRELLQREYFDSFLESSKVYEQGESQVLTNVYGIGNCHIDTAWLWPFAETRRKIVRSWSSQCTLMDRFPEYKFVASQAQQFKWLLEDHPEFFNKVLIPKIQQSQFFAVGGTWVENDTNIPSGESLARQFFFGQRFFLKHFGLKSKIFWLPDTFGYSSQMPQLCRLSGIDKFLTQKLSWNNINSFPHSTFNWAGIDGSQLLTHMPPGNTYTADSHFGDVLRTAKQNKTPEYYGSGLMLYGKGDGGGGPTEEMLQKMRRIRSMNNRNGNVIPKLQVGITVDEFYDDILKRTNQGHDLPTWSGELYFEFHRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDSYKYPS---------KQINELWENVLLCQFHDVLPGSCIEMV 637 HSP 2 Score: 118.627 bits (296), Expect = 2.358e-27 Identity = 104/364 (28.57%), Postives = 169/364 (46.43%), Query Frame = 3
Query: 2319 NVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLV----SKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVIS---RLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGD------NCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPES-------IDLLMCPFAIASIIVEF 3350
N NQ V+YDD PL W AWD Y + + + QV + T+ +V ++ K +++ ++ ++T + S+ +T +W +++ +KV+ P I A Y TQ G RPTH NTSWD AK+EVC H + E + G+++ + +G S G + LSLLR+P +PDA AD H YA++P +R A+ S +LA +FN+ C + L D + ISI N V + IK D +K + + + V+R++E +GG L ++ +K + LE ++ +L T + I + + PF IAS + F
Sbjct: 745 NKLGANQFVIYDDKPLGWQAWDTELYSVNQYKYVTKPKKVQV---SCNTKEKCAVEVIFQISEKCKIKSVISLNATAVTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDFASYETQFGITKRPTHYNTSWDVAKFEVCHHKFADYSEYSKGVSILNDCKYGFSTHGNLMRLSLLRSPKAPDAHADMG--THEIKYAIYP---------HRGALSSDTVKLAHEFNY-CF--KYKLPKDIGMNFDDI----ISISGDEN--VILSNIKRGEDDSAVKSNYSLNPRDEQSIVVRVYESLGGESFASLNTTLNLKRIEKVDNLEMKVYK--SLTATRDESNHAINRIPIKLRPFEIASFRLYF 1083
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Nematostella
Match: EDO33329 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSJ0]) HSP 1 Score: 609.757 bits (1571), Expect = 0.000e+0 Identity = 380/1107 (34.33%), Postives = 576/1107 (52.03%), Query Frame = 3
Query: 57 KNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALP-NSETAYQALHAANQTVNMLVDMTTDSMHQKLI-KARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPPFLINPTSWPLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDI----DQIASFQVFQEAAVTRSNHSVTLVSKFGLE-NSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRF--AVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIVEF 3350
K+WR T ER +KF+S ++F+D N+ + ++ LT + H +++ K ++ + S +K+ + FG TWS HWF++ +VP+EW + + L WNS EA+V G +QGL + + + +LY++ + + +FGAG +GLIN PD + + L A + + + DL +++D+A+ LP S ++ AL+ AN+ VN D+ ++ KA FF+ G + ++A+G+CHID AWLW ET RK RS++T V L+ K+P F CSQAQQ++W++ YP L+ IK QFIPVG TWVEMD N+P ES RQF+ GQ F+KE FG C+EFWLPDTFGYS QLPQI+ GI F+TQKLSWSL+NKFP SF WQG+DGS+ +THFPP D+Y ++L++++N DKGRV +M LYGHGDGG GP+++M+ L R+ + DG PR+ S+P F++ + + +LCTW GEL+LELH GT+TTQ ++K N E ++ + E++ S+V T + +++ K WKL LLNQFHD+LPGT I +V V++ + ++A + P ++N W + ++IP + T + ++ P V+ + + L N+F V +D + R+V L P I GNQLV++DDVPLFWDAWDVM Y+LET I Q +V + S +F L ++ + + Q +T+ + F+T++DW E + +KV+ P +++ A Y Q G RPTH NTSWD AKYEVCG W +L E NWG+++ ++ +G S G +++SLLR P +D H F YA+FP I F + + R A FN + L + C + S S N V ++ +K K +N ++R++E GG+ RL + + N+LEE NG L +D+ F I ++++ F
Sbjct: 9 KHWRCTLERAEKFVSKQFFSDINLYSRLYSNKAPLTAVTHF--AAPGRITYKQAIR-GEYSPVKVGD-----------------AFGPTWSTHWFKVTIDVPSEWAEKEVH----LRWNSGSEAMVWKD-GKPLQGLTGADGHQERTDCILSTCQASSERRYVLYIEMAANGMFGAGQDGLINPPDPARKYSLSMAEIAVFDPLCYQLLTDLNVIIDMAKHLPEGSPRSFDALYTANRIVN-----ACDTKDRRTFEKAHEIAQEFFSQHNGTSQHQVYAVGNCHIDCAWLWPAAETVRKCGRSFATAVQLMKKYPDFKFACSQAQQLEWVKIHYPGLYEEIKKFVANGQFIPVGATWVEMDGNIPSGESFIRQFVVGQQFFKEEFGMMCKEFWLPDTFGYSAQLPQIITGCGIKFFLTQKLSWSLINKFPFSSFFWQGIDGSKCLTHFPPADTYESRGDAKDVLKTSSNLKDKGRVHGSMLLYGHGDGGGGPSEDMIEMLKRMEDVDGCPRVKLSSPHEFFTAVAKRDSSSLCTWVGELYLELHQGTFTTQAEIKSLNRRGEFLLHNAELVTSLVWAL--------GGKTADLYPSQKLLKVWKLFLLNQFHDILPGTCIREVS-----LVELVVNCLDTLNRTVAQEILSAKPIIVNTLGW------ARDECVIIPDALVPNLTDRAIHRQTTSDGKTLGEPF---VLIILFIVPGQVTLE---NEFVRVRLDGVGRVV--SLVHKPSQREAIPCGSHGNQLVLFDDVPLFWDAWDVMPYYLETRKPIVESTKQDNCLRVLDRGPLRAS-------VEFSLRISANSSLTQLVTLDASLPYVTFNTKVDWHENRKFLKVEFPVDVHSMNATYEIQFGHLQRPTHCNTSWDWAKYEVCGQRWCNLSEHNWGVSLMTDSKYGYSTHGSTMYISLLRRPRPRTHQSDMGR--HQFAYAVFPH-------IGSFQDSGLIRHAQCFN-------EKLHVICCSVDEGFEK--QSFFSVDNPAVVLETVK--------KAENVDALILRMYEAFGGKTRARLTTKLNVTKIQRCNLLEEP-DRNGLLSLVDGGVDIPFGSFEIVTLLLYF 1024
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Medaka
Match: man2c1 (mannosidase alpha class 2C member 1 [Source:NCBI gene;Acc:101173055]) HSP 1 Score: 619.387 bits (1596), Expect = 0.000e+0 Identity = 405/1117 (36.26%), Postives = 594/1117 (53.18%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSET-AYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDA--YW----AHRSVLDWCHQVTHSLASILRMVPPFLINPTSWP----LAVQNSAAG----LLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVV--PVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCR-QFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIV 3344
+ KN RT ER +KF+SD YFTD N+ + D L I +PK + + S K D FG TW WF++ +P W + L W S+ E +V G+ +QGL +T+ L+ ++ +DP + + LYV+ +C+ LFGAG +I PD N+ F + A L + + + + ++L+DI + L E YQAL N+ VN D T S +A + +FF + G + ++HA+GHCHID+AWLW + ET RK RSW TV+ L++K+P F CSQAQQ W++ YP LF RI+ ++ QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG +C+EFWLPDTFGYS QLPQIMR GI F+TQKLSW+LVN FPH++F W+GLDGS+V+THFPPG+SY M + +++++ N+ DKGR + + L+G GDGG GP ML L V + DGLPR+ S+PD+ +S L++ + LCTW+GELFLELHNGTYTTQ Q+K N CE ++R VE+ S+ + T E++++ W+L+LLNQFHDV+PG+ V +DA Y+ A S+L H+ +L S + L N W + +++ G L+ +P I+T A AV + +N + Q +LA+LHLI+ A+ CR GNQ V++DDVPL+WDAWDVMDYHL+T ++++ + R++ S TL + + TIV Q + + S + +F+T+++W E H+ +KV+ P + +P A Y Q G RPTH NTSWD A++EV GH W L E N+G+++ ++ +G S+ + LSL+RAP +PD+TAD H F YA+ P F S + +N N R + C + SF ++ KPV+ + + ++ + V+RL+E G L ++ P+K A ++LE R T + I L PF I ++++
Sbjct: 6 VLKNRRTLLERAEKFISDVYFTDCNLRGRLYGDSCPLQSIASF---ISPK-----RIPFSEASTQKFEPYTVGD------------TFGPTWWTCWFKVTLTIPESWRGKEVH----LLWESDGEGMVWKD-GHPVQGLTKEGEKTSYILSDCLQSEDPHSFT---LYVEVACNGLFGAGQGSMIATPDPNRRFSIHKAELVIFNRDVRELLTEFEMLVDIVKELGEREQRGYQALFTVNEMVNR-CDPTDPS---SFSEAHNLACKFFNQRNGESQHTVHAMGHCHIDSAWLWPYEETIRKCGRSWVTVISLMEKNPEFTFTCSQAQQFQWVKSWYPGLFSRIQYFVKKGQFIPVGGTWVEMDGNLPSGESMIRQFLEGQRFFNQEFGTYCKEFWLPDTFGYSAQLPQIMRGCGIPNFLTQKLSWNLVNTFPHNTFFWEGLDGSQVLTHFPPGNSYEMKGKIEDLVKTVKNNKDKGRANHSAALFGFGDGGGGPNQLMLDRLRLVQDTDGLPRVQMSSPDQLFSQLQA-DSSLLCTWTGELFLELHNGTYTTQAQIKRENRQCEALLRDVEIASSLALCRS----------KTFSYPQEKLQRLWRLLLLNQFHDVIPGSCTAMVVEDALKYYEDIRADASIL--LHEACEALGS--KGSTAGLFNSLPWERQEVIEIKDGPGGLDLVLVEVPSIGISTIKAIQPVTAVSVTCQADGTVVMENGILRTAINQDGTLASLHLINAN--REALSDGCR---------------------GNQFVVFDDVPLYWDAWDVMDYHLQTRKPVEEVIQPVHVVSSGGLRASVSFTL----RISDKSTIV-QEIVMDAMSPYLKFNTKVEWAESHKFLKVEFPVRVRSPNATYEIQFGHLQRPTHWNTSWDWARFEVWGHKWADLSEHNFGVSLLNDSKYGYSIHKNTMTLSLIRAPKAPDSTADMG--AHQFTYAIMPH-------TGSFQDASVIQAAYNLNFPLRR----MQCHPDTKAWSSFSVT--------------KPVILETIKQAEDAKGTLVVRLYESHGSSLTATLCTTLPVKEAWHCDLLERRDPAR-PAHVTSDGIMLSFRPFQIVTLLL 1019
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Medaka
Match: man2c1 (mannosidase alpha class 2C member 1 [Source:NCBI gene;Acc:101173055]) HSP 1 Score: 403.29 bits (1035), Expect = 3.628e-126 Identity = 250/630 (39.68%), Postives = 348/630 (55.24%), Query Frame = 3
Query: 51 LFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA-AIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSET-AYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDA 1934
+ KN RT ER +KF+SD YFTD N+ + D L I +PK + + S K D FG TW WF++ +P W + L W S+ E +V G+ +QGL +T+ L+ ++ +DP + + LYV+ +C+ LFGAG +I PD N+ F + A L + + + + ++L+DI + L E YQAL N+ VN D T S +A + +FF + G + ++HA+GHCHID+AWLW + ET RK RSW TV+ L++K+P F CSQAQQ W++ YP LF RI+ ++ QFIPVGGTWVEMD NLP ES+ RQFL GQ F+ + FG +C+EFWLPDTFGYS QLPQIMR GI F+TQKLSW+L FP FP +S ++++ N+ DKGR + + L+G GDGG GP ML L V + DGLPR+ S+PD+ +S L++ + LCTW+GELFLELHNGTYTTQ Q+K N CE ++R VE+ S+ + T E++++ W+L+LLNQFHDV+PG+ V +DA
Sbjct: 6 VLKNRRTLLERAEKFISDVYFTDCNLRGRLYGDSCPLQSIASF---ISPK-----RIPFSEASTQKFEPYTVGD------------TFGPTWWTCWFKVTLTIPESWRGKEVH----LLWESDGEGMVWKD-GHPVQGLTKEGEKTSYILSDCLQSEDPHSFT---LYVEVACNGLFGAGQGSMIATPDPNRRFSIHKAELVIFNRDVRELLTEFEMLVDIVKELGEREQRGYQALFTVNEMVNR-CDPTDPS---SFSEAHNLACKFFNQRNGESQHTVHAMGHCHIDSAWLWPYEETIRKCGRSWVTVISLMEKNPEFTFTCSQAQQFQWVKSWYPGLFSRIQYFVKKGQFIPVGGTWVEMDGNLPSGESMIRQFLEGQRFFNQEFGTYCKEFWLPDTFGYSAQLPQIMRGCGIPNFLTQKLSWNLKTTFP----------------TFPASSLFS-------LVKTVKNNKDKGRANHSAALFGFGDGGGGPNQLMLDRLRLVQDTDGLPRVQMSSPDQLFSQLQA-DSSLLCTWTGELFLELHNGTYTTQAQIKRENRQCEALLRDVEIASSLALCRS----------KTFSYPQEKLQRLWRLLLLNQFHDVIPGSCTAMVVEDA 569
BLAST of Alpha-mannosidase 2C1 vs. Planmine SMEST
Match: SMESG000072790.1 (SMESG000072790.1) HSP 1 Score: 2191 bits (5676), Expect = 0.000e+0 Identity = 1086/1105 (98.28%), Postives = 1090/1105 (98.64%), Query Frame = 3
Query: 42 MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLAAIEPDDPLNRSHRLLYVQASCSDLFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSSCEQMMRSVEMLXXXXXXXXXXXEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPPFLINPTSWPLAVQNSAAGLLVIPPCXXXXXXXXXXXXXXXXXXXXXQVPIRDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDQIASFQVFQEAAVTRSNHSVTLVSKFGLENSGTIVEQSLTVTERSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVWNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKPVMCDCQLKGDNCRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIVEFAE 3356
MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLA IEPDDPLNRSHRLLYVQASCS+LFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNS CEQMMRSVEMLVSIVIVSRVRSEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPPFLINPTSWPLAVQNSAAGLLVIPP SIATATATSDADAVVT TVDSQVPI DNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDID+IASFQVFQEAAVTRSNHSVTLVSKFGLEN+GTIVEQSLTVTE SEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCV NRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKP KGDN RQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIVEFA+
Sbjct: 1 MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTNPKLSTKDSLELFDKSALKIPEVLSMDGNQWETIDKANFVFGKTWSIHWFRLEFNVPTEWEKDSENFTPELHWNSECEALVVNSHGNIIQGLNATHSRTAVSLATIEPDDPLNRSHRLLYVQASCSELFGAGNNGLINAPDMNKSFKLVTARLQLTSVAASTVQRDLKLLLDIAEALPNSETAYQALHAANQTVNMLVDMTTDSMHQKLIKARHFLDRFFASKLGGDRLSLHAIGHCHIDTAWLWRFGETRRKLARSWSTVVGLLDKHPSMAFVCSQAQQMDWLREDYPDLFIRIKALCERKQFIPVGGTWVEMDVNLPCCESLCRQFLYGQNFYKEHFGAFCREFWLPDTFGYSPQLPQIMRQAGISRFMTQKLSWSLVNKFPHHSFIWQGLDGSRVVTHFPPGDSYSMTCSVPEMLRSATNHADKGRVSCAMYLYGHGDGGQGPTDEMLYALDRVANFDGLPRITHSTPDRFYSDLESGNMDNLCTWSGELFLELHNGTYTTQRQLKLGNSICEQMMRSVEMLVSIVIVSRVRSEQGDSAMTTVVTILEQIEKQWKLILLNQFHDVLPGTSIEQVCDDAYWAHRSVLDWCHQVTHSLASILRMVPPFLINPTSWPLAVQNSAAGLLVIPPYSIATATATSDADAVVTVTVDSQVPIPDNVVPVDYQFDSLANLHLISNQFFTVAVDSLCRIVRMRLRSHPESMNIISNVGSGNQLVMYDDVPLFWDAWDVMDYHLETGTDIDRIASFQVFQEAAVTRSNHSVTLVSKFGLENTGTIVEQSLTVTEHSEFCQFSTRIDWREKHRMVKVKVPTVINAPEAQYRTQAGFHSRPTHRNTSWDTAKYEVCGHDWIHLGEANWGIAVFKEAIFGSSVIGGNVFLSLLRAPTSPDATADRKYLPHVFNYALFPFDCTATNMINRFAVISRLATQFNWNCVGNRDSLIIDCAGQLQQVHSFPISIGSPSNGEVAIDWIKP-------KGDNYRQFVMRLHEQIGGRFLVRLISSAPIKSAALSNILEERLVTNGNLCCTPESIDLLMCPFAIASIIVEFAD 1098 The following BLAST results are available for this feature:
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Alpha-mannosidase 2C1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Alpha-mannosidase 2C1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Alpha-mannosidase 2C1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Alpha-mannosidase 2C1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30011873 ID=SMED30011873|Name=Alpha-mannosidase 2C1|organism=Schmidtea mediterranea sexual|type=transcript|length=3531bpback to top protein sequence of SMED30011873-orf-1 >SMED30011873-orf-1 ID=SMED30011873-orf-1|Name=SMED30011873-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1106bp MASLFKNWRTTSERIDKFLSDKYFTDANITKIIIADVKELTKIEHLKIVTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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