Very-long-chain 3-oxoacyl-CoA reductase

Overview
NameVery-long-chain 3-oxoacyl-CoA reductase
Smed IDSMED30011844
Length (bp)1121
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Very-long-chain 3-oxoacyl-CoA reductase (SMED30011844) t-SNE clustered cells

Violin plots show distribution of expression levels for Very-long-chain 3-oxoacyl-CoA reductase (SMED30011844) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Very-long-chain 3-oxoacyl-CoA reductase (SMED30011844) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Very-long-chain 3-oxoacyl-CoA reductase (SMED30011844) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30011844

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30011844SMESG000075064.1 dd_Smed_v4_3371_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30011844SMESG000075064.1 dd_Smed_v4_3371_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011844SMESG000075064.1 dd_Smed_v4_3371_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Human
Match: HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:18646])

HSP 1 Score: 184.111 bits (466), Expect = 8.526e-55
Identity = 110/274 (40.15%), Postives = 168/274 (61.31%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            Y+ + I +S+F    +        +    G+WAVVTG+TDGIG+ Y  +LAK G+ V LISR + KL+  S E+K+ +K++      DFAS  IY+ +K  + GL+IG+LVNNVG+       F+D+ +  ++   +    + +V  M++++   M +R +G I+NISS S + P+P+ TIYSATK+F+  FS  L+EE    G+ VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H++ G I+ ++P +I +KI
Sbjct:   21 YLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL-AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Human
Match: HSDL1 (hydroxysteroid dehydrogenase like 1 [Source:HGNC Symbol;Acc:HGNC:16475])

HSP 1 Score: 164.466 bits (415), Expect = 3.993e-47
Identity = 96/276 (34.78%), Postives = 156/276 (56.52%), Query Frame = 3 
Query:  159 FSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASN-SIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAA---FRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            +S+ +  F+ +      LIK+ G+WAVV+GATDGIG+ Y  +LA  GLN+ LISR+E+KL++ +K++   YK++     ADF+S   IY  ++E +K  D+G+LVNNVG+  P    F  + E      I      +++M+  ++   M +RK+G I+ ISS S   P P    +SA+K++L HFS AL  E +  GI VQ++ PF+V T + A         + +P  + +   A+ T+G    T G   HSIQ +  + +P ++ +    ++ R
Sbjct:   45 YSLIRLHFIPRLGSRADLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVLPG-MVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANILNR 319
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Human
Match: HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212])

HSP 1 Score: 147.517 bits (371), Expect = 8.540e-41
Identity = 98/266 (36.84%), Postives = 156/266 (58.65%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVV-CDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIP--LFISIKIGKMIFRYFQSNLKLR 1001
            ++  G+WAV+TGA DGIG+ Y  +LAK GLNV LISR  +KLE  + E+++     V   QADF  + IYE +KE++ GL+IG+LVNNVG+   ++   F++  +   +  +I+ NI S V M+++I   M  R++G+I+NISS  +L P P+ ++YSA+K+F+  FS AL EE     +++Q + P+ V T +              +EFV+ ++  V   G+T G L H I    +  IP   F S    +++  ++ + LKL 
Sbjct:   44 LRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPD--EIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLN-TNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLN 306
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Human
Match: HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:HGNC Symbol;Acc:HGNC:5212])

HSP 1 Score: 143.28 bits (360), Expect = 1.858e-39
Identity = 90/232 (38.79%), Postives = 140/232 (60.34%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSI 908
            ++  G+WAV+TGA DGIG+ Y  +LAK GLNV LISR  +KLE  + E+++     V   QADF  + IYE +KE++ GL+IG+LVNNVG+   ++     ++    +  +I+ NI S V M+++I   M  R++G+I+NISS  +L P P+ ++YSA+K+F+  FS AL EE     +++Q + P+ V T +              +EFV+ ++  V   G+T G L H I
Sbjct:   44 LRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHF-LNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLN-TNVITKTADEFVKESLNYVTIGGETCGCLAHEI 273
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Human
Match: HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:18646])

HSP 1 Score: 135.961 bits (341), Expect = 9.182e-37
Identity = 95/274 (34.67%), Postives = 145/274 (52.92%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            Y+ + I +S+F    +        +    G+WAVVTG+TDGIG+ Y  +LAK G+ V LISR + KL+  S E+                                    +NNVG+       F+D+ +  ++   +    + +V  M++++   M +R +G I+NISS S + P+P+ TIYSATK+F+  FS  L+EE    G+ VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H++ G I+ ++P +I +KI
Sbjct:   21 YLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEI------------------------------------MNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL-AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKI 257
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Celegans
Match: stdh-2 (Putative steroid dehydrogenase 2 [Source:UniProtKB/Swiss-Prot;Acc:O17795])

HSP 1 Score: 138.272 bits (347), Expect = 9.875e-38
Identity = 109/294 (37.07%), Postives = 168/294 (57.14%), Query Frame = 3 
Query:  126 WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESG-KWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKE-LKKCYKIDVMYFQADFASNSI--YESLKERMKGLDIGVLVNNVGI--QQPVVCDFID--IDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFI---SIKIGKMIFR 974
            ++F++ I  I+  +  Y F     + + L K++G  WAVVTGATDGIG+ Y  +LA+ G NV+++SR + KLE T K+ L+K   I+V +   DF + S+  YE L  ++  + +G+L+NNVG+    P +   I+  ID    ++ +I IN L A ++S  I  +M  RK GII+NI S + +  L   +IYSATK ++   +  L +E S +GI+ Q + P  V TK+ A      FF P  + F  SA+ T+G   +T G + H IQ  I++ +P F+   SIK G   FR
Sbjct:   17 YIFYHFIRIILNILVPYAFC----QPIDLKKKAGASWAVVTGATDGIGKSYSFELARRGFNVYIVSRTQSKLEQTKKDILEKQPDIEVRFATYDFTNPSVTDYEKLLSKLNEVSVGILINNVGMFFDYPEMLHKINGGIDS---IANVIIINTLPATLLSAGILPQMVSRKAGIIVNIGSFAGVVKLAEWSIYSATKKYVEWLTGCLRKEYSHHGIIFQAITPAMVATKM-AGNPNTSFFCPDSDTFARSALNTIGHASETTGYIAHQIQCEILKLLPDFVIDRSIKKGNAEFR 302
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517])

HSP 1 Score: 135.191 bits (339), Expect = 1.461e-36
Identity = 100/257 (38.91%), Postives = 147/257 (57.20%), Query Frame = 3 
Query:  204 VKLIKESG-KWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKE-LKKCYKIDVMYFQADF--ASNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            + L K +G  WAVVTGATDGIG+ Y  +LA+ G NV L+SR + KL+ T KE L+K   I+V     DF  A+ S Y+ L   +  ++IGVL+NNVG+  + P V   +D      L+ I  IN L   ++S  I  +M  RK G+I+N+ S++  + + +  +YSATK +++  +  L +E    GI VQT+ P  V TK+ +  +   FF P    F +SA+ TVG   DT G + H +Q  ++  IP FI  KI
Sbjct:   39 IDLKKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVD-GGIERLANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQGITVQTIAPMMVATKM-SKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMDLIPTFIRDKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517])

HSP 1 Score: 135.191 bits (339), Expect = 1.461e-36
Identity = 100/257 (38.91%), Postives = 147/257 (57.20%), Query Frame = 3 
Query:  204 VKLIKESG-KWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKE-LKKCYKIDVMYFQADF--ASNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            + L K +G  WAVVTGATDGIG+ Y  +LA+ G NV L+SR + KL+ T KE L+K   I+V     DF  A+ S Y+ L   +  ++IGVL+NNVG+  + P V   +D      L+ I  IN L   ++S  I  +M  RK G+I+N+ S++  + + +  +YSATK +++  +  L +E    GI VQT+ P  V TK+ +  +   FF P    F +SA+ TVG   DT G + H +Q  ++  IP FI  KI
Sbjct:   39 IDLKKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVD-GGIERLANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQGITVQTIAPMMVATKM-SKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMDLIPTFIRDKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517])

HSP 1 Score: 134.806 bits (338), Expect = 2.906e-36
Identity = 100/257 (38.91%), Postives = 147/257 (57.20%), Query Frame = 3 
Query:  204 VKLIKESG-KWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKE-LKKCYKIDVMYFQADF--ASNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            + L K +G  WAVVTGATDGIG+ Y  +LA+ G NV L+SR + KL+ T KE L+K   I+V     DF  A+ S Y+ L   +  ++IGVL+NNVG+  + P V   +D      L+ I  IN L   ++S  I  +M  RK G+I+N+ S++  + + +  +YSATK +++  +  L +E    GI VQT+ P  V TK+ +  +   FF P    F +SA+ TVG   DT G + H +Q  ++  IP FI  KI
Sbjct:   56 IDLKKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVD-GGIERLANITTINTLPPTLLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQGITVQTIAPMMVATKM-SKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMDLIPTFIRDKI 310
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Celegans
Match: let-767 (Very-long-chain 3-oxooacyl-coA reductase let-767 [Source:UniProtKB/Swiss-Prot;Acc:Q09517])

HSP 1 Score: 132.88 bits (333), Expect = 1.868e-35
Identity = 93/260 (35.77%), Postives = 145/260 (55.77%), Query Frame = 3 
Query:  204 VKLIKESG-KWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKE-LKKCYKIDVMYFQADF--ASNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISA---EMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            + L K +G  WAVVTGATDGIG+ Y  +LA+ G NV L+SR + KL+ T KE L+K   I+V     DF  A+ S Y+ L   +  ++IGVL+NNVG+  + P V   +D       +      +   + ++++ +    +M  RK G+I+N+ S++  + + +  +YSATK +++  +  L +E    GI VQT+ P  V TK+ +  +   FF P    F +SA+ TVG   DT G + H +Q  ++  IP FI  KI
Sbjct:   56 IDLKKRAGASWAVVTGATDGIGKAYAFELARRGFNVLLVSRTQSKLDETKKEILEKYSSIEVRTAAFDFTNAAPSAYKDLLATLNQVEIGVLINNVGMSYEYPDVLHKVDGGIERLANITTINTLPPTLFLTQLSAGILPQMVARKAGVIVNVGSSAGANQMALWAVYSATKKYVSWLTAILRKEYEHQGITVQTIAPMMVATKM-SKVKRTSFFTPDGAVFAKSALNTVGNTSDTTGYITHQLQLELMDLIPTFIRDKI 314
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0345747)

HSP 1 Score: 166.392 bits (420), Expect = 3.142e-48
Identity = 103/261 (39.46%), Postives = 163/261 (62.45%), Query Frame = 3 
Query:  210 LIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIA-AFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            L+ + G+WAVVTGATDGIG+EY R+LA+ G+N+ LISR ++KL   + E++  YK+   +  ADFA    +Y+ +++ + G+D+G+LVNNVG+  + P   D +  D    L  ++ +N+ S  M+++ I  +M  R++G I+N+ S+S L PLP  T+Y+A+K F+T+FS AL  E++++ I VQ V P FV TK+ A   R+ +   F P    F  SA+ T+G   +T G   H IQ  I++  PL I   +G  +F+
Sbjct:   51 LVDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPESLDLVSED---LLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQYAIMKLAPLPIRTYLGHQLFK 308
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0080926)

HSP 1 Score: 166.392 bits (420), Expect = 3.142e-48
Identity = 103/261 (39.46%), Postives = 163/261 (62.45%), Query Frame = 3 
Query:  210 LIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIA-AFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            L+ + G+WAVVTGATDGIG+EY R+LA+ G+N+ LISR ++KL   + E++  YK+   +  ADFA    +Y+ +++ + G+D+G+LVNNVG+  + P   D +  D    L  ++ +N+ S  M+++ I  +M  R++G I+N+ S+S L PLP  T+Y+A+K F+T+FS AL  E++++ I VQ V P FV TK+ A   R+ +   F P    F  SA+ T+G   +T G   H IQ  I++  PL I   +G  +F+
Sbjct:   51 LVDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPESLDLVSED---LLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQYAIMKLAPLPIRTYLGHQLFK 308
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0332333)

HSP 1 Score: 166.392 bits (420), Expect = 4.441e-48
Identity = 103/261 (39.46%), Postives = 163/261 (62.45%), Query Frame = 3 
Query:  210 LIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIA-AFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            L+ + G+WAVVTGATDGIG+EY R+LA+ G+N+ LISR ++KL   + E++  YK+   +  ADFA    +Y+ +++ + G+D+G+LVNNVG+  + P   D +  D    L  ++ +N+ S  M+++ I  +M  R++G I+N+ S+S L PLP  T+Y+A+K F+T+FS AL  E++++ I VQ V P FV TK+ A   R+ +   F P    F  SA+ T+G   +T G   H IQ  I++  PL I   +G  +F+
Sbjct:   64 LVDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPESLDLVSED---LLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQYAIMKLAPLPIRTYLGHQLFK 321
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0332334)

HSP 1 Score: 166.392 bits (420), Expect = 5.167e-48
Identity = 103/261 (39.46%), Postives = 163/261 (62.45%), Query Frame = 3 
Query:  210 LIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIA-AFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            L+ + G+WAVVTGATDGIG+EY R+LA+ G+N+ LISR ++KL   + E++  YK+   +  ADFA    +Y+ +++ + G+D+G+LVNNVG+  + P   D +  D    L  ++ +N+ S  M+++ I  +M  R++G I+N+ S+S L PLP  T+Y+A+K F+T+FS AL  E++++ I VQ V P FV TK+ A   R+ +   F P    F  SA+ T+G   +T G   H IQ  I++  PL I   +G  +F+
Sbjct:   65 LVDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPESLDLVSED---LLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQYAIMKLAPLPIRTYLGHQLFK 322
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Fly
Match: CG13284 (gene:FBgn0032614 transcript:FBtr0080927)

HSP 1 Score: 166.392 bits (420), Expect = 5.167e-48
Identity = 103/261 (39.46%), Postives = 163/261 (62.45%), Query Frame = 3 
Query:  210 LIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGI--QQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIA-AFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            L+ + G+WAVVTGATDGIG+EY R+LA+ G+N+ LISR ++KL   + E++  YK+   +  ADFA    +Y+ +++ + G+D+G+LVNNVG+  + P   D +  D    L  ++ +N+ S  M+++ I  +M  R++G I+N+ S+S L PLP  T+Y+A+K F+T+FS AL  E++++ I VQ V P FV TK+ A   R+ +   F P    F  SA+ T+G   +T G   H IQ  I++  PL I   +G  +F+
Sbjct:   65 LVDKFGQWAVVTGATDGIGKEYARELARQGINLVLISRTKEKLIAVTNEIESQYKVKTKWIAADFAKGREVYDQIEKELAGIDVGILVNNVGMMYEHPESLDLVSED---LLWNLLTVNMGSVTMLTRKILPQMIGRRKGAIVNLGSSSELQPLPNMTVYAASKKFVTYFSKALELEVAEHNIHVQLVMPNFVVTKMNAYTDRVMQGGLFFPNAYTFARSAVFTLGKTSETNGFWTHGIQYAIMKLAPLPIRTYLGHQLFK 322
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Zebrafish
Match: hsd20b2 (hydroxysteroid (20-beta) dehydrogenase 2 [Source:ZFIN;Acc:ZDB-GENE-030804-21])

HSP 1 Score: 164.466 bits (415), Expect = 2.696e-47
Identity = 103/241 (42.74%), Postives = 150/241 (62.24%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGIQQ-PVVCDFIDI-DEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLP-KFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIV 923
            ++  G+WAVVTGAT GIGR Y  +LAK GLN+ LISR E+KL   +KE++  Y       QADF   +SIY ++ ++++GL+IG+LVNNVG+    V+ +F+D+ D    ++ ++N N LS   M ++I   M +R +G+IINISS +   P+PM ++YSATK+F+T+FSL LN E    GI VQ V PF V T +     +P    +     F   A+ TVG    T G L H++Q I++
Sbjct:   50 LRTYGRWAVVTGATSGIGRAYAEELAKRGLNIVLISRSEEKLHRVAKEIEDKYNQKTHVIQADFTEGHSIYSTITKQLEGLEIGILVNNVGMNYIGVLANFLDVPDPDQRITQVLNCNTLSVTQMCRVILPGMVERGKGLIINISSEAGYQPVPMVSLYSATKAFVTYFSLGLNAEYRSKGITVQCVAPFMVSTNM--THNVPVNPLVKSAASFARDALNTVGYTTYTSGCLTHALQHIVL 288
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Zebrafish
Match: hsd20b2 (hydroxysteroid (20-beta) dehydrogenase 2 [Source:ZFIN;Acc:ZDB-GENE-030804-21])

HSP 1 Score: 164.466 bits (415), Expect = 2.696e-47
Identity = 103/241 (42.74%), Postives = 150/241 (62.24%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGIQQ-PVVCDFIDI-DEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLP-KFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIV 923
            ++  G+WAVVTGAT GIGR Y  +LAK GLN+ LISR E+KL   +KE++  Y       QADF   +SIY ++ ++++GL+IG+LVNNVG+    V+ +F+D+ D    ++ ++N N LS   M ++I   M +R +G+IINISS +   P+PM ++YSATK+F+T+FSL LN E    GI VQ V PF V T +     +P    +     F   A+ TVG    T G L H++Q I++
Sbjct:   50 LRTYGRWAVVTGATSGIGRAYAEELAKRGLNIVLISRSEEKLHRVAKEIEDKYNQKTHVIQADFTEGHSIYSTITKQLEGLEIGILVNNVGMNYIGVLANFLDVPDPDQRITQVLNCNTLSVTQMCRVILPGMVERGKGLIINISSEAGYQPVPMVSLYSATKAFVTYFSLGLNAEYRSKGITVQCVAPFMVSTNM--THNVPVNPLVKSAASFARDALNTVGYTTYTSGCLTHALQHIVL 288
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Zebrafish
Match: hsd17b12b (hydroxysteroid (17-beta) dehydrogenase 12b [Source:NCBI gene;Acc:322626])

HSP 1 Score: 163.696 bits (413), Expect = 3.861e-47
Identity = 94/248 (37.90%), Postives = 151/248 (60.89%), Query Frame = 3 
Query:  192 SNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSI 932
             N ++      GKWAVVTGATDGIG+ Y  +LA+ G  + LISR ++KL+  SK ++  YK++     ADF S  IY  ++  + GL+IGVLVNNVG+       F++I +  S    +    + +V  M++++   M  R +G+I+N++SAS + P+P+ T+YS+TK+F+  FS  L+ E    GI++Q+V PF+V TKL +  R P   +P  E +V++ + T+G +  + G L H+I G +  S+
Sbjct:   37 GNGNLMRASSLGKWAVVTGATDGIGKAYAEELARRGFAIVLISRTQEKLDEVSKAIESKYKVETKTISADFGSVDIYPKIESGLAGLEIGVLVNNVGVSYSYPEFFLNIPDVDSFINNMININIMSVCQMTRLVLPRMVDRSKGVILNVASASGMYPVPLLTLYSSTKAFVDFFSRGLDAEYKSKGIIIQSVLPFYVTTKL-SKIRKPTLDIPTPERYVKAQLSTIGLQTQSNGYLPHAIMGWVTASL 283
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Zebrafish
Match: hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1339])

HSP 1 Score: 162.155 bits (409), Expect = 1.240e-46
Identity = 94/242 (38.84%), Postives = 146/242 (60.33%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGI-QQPVVCDFIDIDEXXXXXXXXXXXXXXA-VMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFI 944
            GKWAV+TG +DGIGR Y  +L+K G++V +ISR+++KL+  +K+++      V    ADF  + IY  + E ++GLDIGVLVNNVGI    + C  ++  +       I    + + V M +I+   M QR+RG+I+N+SS  +  P P+ T+Y+A+K F+  FS  L  E    GI++QTV PF V T +    + P       EEFV S+++ + T   T+GS+ H++ G IV+SIP ++
Sbjct:   47 GKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSDLEERIYDIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKGIIIQTVAPFGVSTAM-TGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHTLLGRIVQSIPTWV 287
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Zebrafish
Match: hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1339])

HSP 1 Score: 161.77 bits (408), Expect = 1.740e-46
Identity = 93/242 (38.43%), Postives = 146/242 (60.33%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGI-QQPVVCDFIDIDEXXXXXXXXXXXXXXA-VMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFI 944
            GKWAV+TG +DGIGR Y  +L+K G++V +ISR+++KL+  +K+++      V    ADF  + IY  + E ++GLDIGVLVNNVGI    + C  ++  +       I    + + V M +I+   M QR+RG+I+N+SS  +  P P+ T+Y+A+K F+  FS  L  E    G+++QTV PF V T +    + P       EEFV S+++ + T   T+GS+ H++ G IV+SIP ++
Sbjct:   47 GKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSDLEERIYDIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKGVIIQTVAPFGVSTAM-TGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHTLLGRIVQSIPTWV 287
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988])

HSP 1 Score: 169.088 bits (427), Expect = 5.094e-49
Identity = 105/248 (42.34%), Postives = 157/248 (63.31%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIG 959
            GKWAVVTGATDGIG+ Y  +LAK G+N+ LISR  +KLE  +K++K+ +K++     ADF   + IY  ++  ++ L+IGVLVNNVG+       F++I +  +    +    +++V  M++++   M  R RG+I+NISSAS + P+P+ T+YSATK+F+  FS  L  E    G+ VQ+V PF+V TKL A  R P +  P  E +V+SA+ TVG +  T G L H+I G I  S +P+  +I +G
Sbjct:   56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL-AKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAISLG 302
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988])

HSP 1 Score: 167.548 bits (423), Expect = 1.857e-48
Identity = 105/247 (42.51%), Postives = 154/247 (62.35%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIG 959
            GKWAVVTGATDGIG+ Y  +LAK G+N+ LISR  +KLE  +K++K+ +K++     ADF   + IY  ++  ++ L+IGVLVNNVG+       F++I +  ++S            M++++   M  R RG+I+NISSAS + P+P+ T+YSATK+F+  FS  L  E    G+ VQ+V PF+V TKL A  R P +  P  E +V+SA+ TVG +  T G L H+I G I  S +P+  +I +G
Sbjct:   56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENVSTNH--------TMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL-AKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAISLG 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988])

HSP 1 Score: 161.77 bits (408), Expect = 3.039e-46
Identity = 103/247 (41.70%), Postives = 153/247 (61.94%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIG 959
            GKWAVVTGATDGIG+ Y  +LAK G+N+ LISR  +KLE  +K++K+ +K++     ADF   + IY  ++  ++ L+IGVLVNNVG+       F++I +  +    +    +++V   +I+        RG+I+NISSAS + P+P+ T+YSATK+F+  FS  L  E    G+ VQ+V PF+V TKL A  R P +  P  E +V+SA+ TVG +  T G L H+I G I  S +P+  +I +G
Sbjct:   56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQVRIVGF----LGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL-AKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAISLG 297
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Xenopus
Match: hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:NCBI gene;Acc:549988])

HSP 1 Score: 155.606 bits (392), Expect = 5.948e-44
Identity = 101/247 (40.89%), Postives = 147/247 (59.51%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIG 959
            GKWAVVTGATDGIG+ Y  +LAK G+N+ LISR  +KLE  +K++K+ +K++     ADF   + IY  ++  ++ L+IGVLVNNVG+       F++I +  +            V  +  +         G+I+NISSAS + P+P+ T+YSATK+F+  FS  L  E    G+ VQ+V PF+V TKL A  R P +  P  E +V+SA+ TVG +  T G L H+I G I  S +P+  +I +G
Sbjct:   56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLEN------------VSTNHTVQQLPLTDPVGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL-AKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAISLG 289
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Xenopus
Match: ENSXETT00000003444.1 (estradiol 17-beta-dehydrogenase 12-B-like [Source:NCBI gene;Acc:100497556])

HSP 1 Score: 146.747 bits (369), Expect = 2.719e-40
Identity = 90/238 (37.82%), Postives = 141/238 (59.24%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASN-SIYESLKERMKGLDIGVLVNNVGI---QQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQ 911
            +++ G WAVVTGATDGIG+ Y  +LA+ G ++ LISR  +KL+  ++ +++         QAD+  +  IY  ++E +KGLDIGVLVNNVG+    +PV   F+D+         +    + +V+ M++I+   M ++K+G+IINISS +   P PM  +YS+TK F+ +FS  L+ E S  GI VQ+V P  V T +    +    F+   + +V  A+ TVG+   T G L H++Q
Sbjct:   74 LRQYGTWAVVTGATDGIGKSYAEELARRGFDIVLISRSPEKLQRVAEGIEQKSGRKTKIIQADYTGDVGIYTPIEEGLKGLDIGVLVNNVGMAYSNEPV--RFLDVPNVKERLTNVINCNIVSVLQMTRIVLPGMLKKKKGLIINISSEAGSHPFPMVAVYSSTKVFVDYFSRCLHTEYSPQGITVQSVMPLLVSTNMTFGIK-SNIFVKTSDSYVYDALNTVGSTTRTNGCLSHALQ 308
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Mouse
Match: Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12 [Source:MGI Symbol;Acc:MGI:1926967])

HSP 1 Score: 165.622 bits (418), Expect = 8.376e-48
Identity = 100/245 (40.82%), Postives = 151/245 (61.63%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            G+WAVVTG TDGIG+ Y  +LAK G+ + LISR + KL   S  +K+ + ++      DF+ + IY+ +K  + GL+IGVLVNNVG+       F++I +  +    +    + +V  +++++   M +R +G+I+NISSAS + P+P+ TIYSATK+F+  FS  L+EE    GI VQ+V P+ V TKL A  + P    P  E FV+SAI+TVG +  T G + HS+ G I   +P ++  KI
Sbjct:   50 GEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKL-AKIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Mouse
Match: Hsdl1 (hydroxysteroid dehydrogenase like 1 [Source:MGI Symbol;Acc:MGI:1919802])

HSP 1 Score: 156.377 bits (394), Expect = 2.386e-44
Identity = 98/277 (35.38%), Postives = 159/277 (57.40%), Query Frame = 3 
Query:  159 FSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAA----FRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            +S+ +  F+ +      LIK+ G+WAV++GATDGIG+ Y  +LA  GLNV LIS++E+KL+  +K +   Y+++ +   ADF+    IY  ++E ++  DIG+LVN+VG   P    F  + E  +L  I+N+NI +A +M  I+   M +RK+G I+ +SS S   P P    +SA+K++L HFS AL  E +  GI VQ++ PF+V +   A      R P +  P    + + A+ T+G    T G   HSIQ +  + +P ++ +    ++ R
Sbjct:   24 YSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPE-DTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSGAAPASFLHRCP-WLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNR 298
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Mouse
Match: Hsdl1 (hydroxysteroid dehydrogenase like 1 [Source:MGI Symbol;Acc:MGI:1919802])

HSP 1 Score: 155.992 bits (393), Expect = 4.624e-44
Identity = 98/277 (35.38%), Postives = 159/277 (57.40%), Query Frame = 3 
Query:  159 FSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAA----FRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFR 974
            +S+ +  F+ +      LIK+ G+WAV++GATDGIG+ Y  +LA  GLNV LIS++E+KL+  +K +   Y+++ +   ADF+    IY  ++E ++  DIG+LVN+VG   P    F  + E  +L  I+N+NI +A +M  I+   M +RK+G I+ +SS S   P P    +SA+K++L HFS AL  E +  GI VQ++ PF+V +   A      R P +  P    + + A+ T+G    T G   HSIQ +  + +P ++ +    ++ R
Sbjct:   45 YSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEEKLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPE-DTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSGAAPASFLHRCP-WLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNR 319
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Mouse
Match: Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:MGI Symbol;Acc:MGI:107177])

HSP 1 Score: 140.584 bits (353), Expect = 1.948e-38
Identity = 91/241 (37.76%), Postives = 146/241 (60.58%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIP 935
            ++  G+WAV+TGA DGIG+ Y  +LA+ GLNV LISR  +KL+  ++E+++     V   QADF    IY+ +KE ++GL+IG+LVNNVG+  P       +  S     +I+ NI S V M++++   M  R++G+I+NISS ++L P P+ ++YSA+K+F+  FS AL+ E    GI++Q + P+ + T +     L        +EFV+ +++ V    ++ G L H I  II+  IP
Sbjct:   40 LRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGM-LPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTK--YLNNKMTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIP 277
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Mouse
Match: Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3 [Source:MGI Symbol;Acc:MGI:107177])

HSP 1 Score: 140.584 bits (353), Expect = 1.948e-38
Identity = 91/241 (37.76%), Postives = 146/241 (60.58%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIP 935
            ++  G+WAV+TGA DGIG+ Y  +LA+ GLNV LISR  +KL+  ++E+++     V   QADF    IY+ +KE ++GL+IG+LVNNVG+  P       +  S     +I+ NI S V M++++   M  R++G+I+NISS ++L P P+ ++YSA+K+F+  FS AL+ E    GI++Q + P+ + T +     L        +EFV+ +++ V    ++ G L H I  II+  IP
Sbjct:   40 LRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGM-LPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTK--YLNNKMTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIP 277
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. UniProt/SwissProt
Match: sp|Q53GQ0|DHB12_HUMAN (Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2)

HSP 1 Score: 184.111 bits (466), Expect = 4.094e-54
Identity = 110/274 (40.15%), Postives = 168/274 (61.31%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            Y+ + I +S+F    +        +    G+WAVVTG+TDGIG+ Y  +LAK G+ V LISR + KL+  S E+K+ +K++      DFAS  IY+ +K  + GL+IG+LVNNVG+       F+D+ +  ++   +    + +V  M++++   M +R +G I+NISS S + P+P+ TIYSATK+F+  FS  L+EE    G+ VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H++ G I+ ++P +I +KI
Sbjct:   21 YLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL-AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. UniProt/SwissProt
Match: sp|Q4R5G7|DHB12_MACFA (Very-long-chain 3-oxoacyl-CoA reductase OS=Macaca fascicularis OX=9541 GN=HSD17B12 PE=2 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 3.340e-52
Identity = 109/274 (39.78%), Postives = 164/274 (59.85%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            Y+ + I +S+F    +        +    G+WAVVTG TDGIG+ Y  +LAK G+ V LISR + KL+  S E+K+ +K++      DF    IY+ +K  + GL+IG+LVNNVG+       F+D+ +  ++   +    + +V  M++++   M +R +G I+NISS S + P+P+ TIYSATK+F+  FS  L+EE    GI VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H + G I+ ++P +I +KI
Sbjct:   21 YLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGGTDGIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEKFKVETRTIAVDFTLEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMFPVPLLTIYSATKTFVDFFSQCLHEEYRSKGIFVQSVLPYFVATKL-AKIRKPTLDKPTPETFVKSAIKTVGLQSRTNGYLIHVLMGWIISNLPSWIYLKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. UniProt/SwissProt
Match: sp|Q5E9H7|DHB12_BOVIN (Very-long-chain 3-oxoacyl-CoA reductase OS=Bos taurus OX=9913 GN=HSD17B12 PE=2 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 9.990e-50
Identity = 99/246 (40.24%), Postives = 152/246 (61.79%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIG 959
            G+WAVVTG TDGIG+ Y  +LAK G+ + LISR + KL+  S E+ + +K++      DF S  IY+ +K  + GL+IGVLVNNVG+       F+D+ +  +    +      +V  M++++   M +R +G I+NISSAS + P+P+ TIYSATK+F+  FS  L+EE    G++VQ+V P++V TKL A  + P +  P  E FV+SA++T+G +  T G   HS+   +  S+P ++  KI 
Sbjct:   50 GEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLDQVSSEISEKFKVETKTIAVDFTSEDIYDKIKASLAGLNIGVLVNNVGMSYEYPEYFLDVPDLDNTIKKLITVNALSVCKMTRLVLPGMVERSKGAILNISSASGMYPVPLLTIYSATKAFVDFFSQCLHEEYKSKGVIVQSVLPYYVATKL-AKIKRPTWDKPSPETFVKSAMKTIGVQSRTNGYPIHSLVASVSASLPSWLYFKIA 294
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. UniProt/SwissProt
Match: sp|Q6P7R8|DHB12_RAT (Very-long-chain 3-oxoacyl-CoA reductase OS=Rattus norvegicus OX=10116 GN=Hsd17b12 PE=2 SV=1)

HSP 1 Score: 169.474 bits (428), Expect = 1.718e-48
Identity = 101/244 (41.39%), Postives = 152/244 (62.30%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIK 953
            G+WAVVTG TDGIG+ Y  +LAK G+ + LISR + KL+  S  +K+ + ++      DF+ + IY+ +K  + GL+IGVLVNNVG+       F++I +  +    +    + ++  +++++   M +R +G+I+NISSAS + P+P+ T+YSATK+F+  FS  L+EE    GI VQ+V PFFV TKL A  R P    P  E FV+SAI+TVG +  T G + H+I G I   +P +I  K
Sbjct:   50 GEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSICKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPFFVATKL-AKIRKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHAIMGSINSILPRWIYFK 292
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. UniProt/SwissProt
Match: sp|Q28IU1|DHB12_XENTR (Very-long-chain 3-oxoacyl-CoA reductase OS=Xenopus tropicalis OX=8364 GN=hsd17b12 PE=2 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 2.699e-48
Identity = 105/248 (42.34%), Postives = 157/248 (63.31%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIG 959
            GKWAVVTGATDGIG+ Y  +LAK G+N+ LISR  +KLE  +K++K+ +K++     ADF   + IY  ++  ++ L+IGVLVNNVG+       F++I +  +    +    +++V  M++++   M  R RG+I+NISSAS + P+P+ T+YSATK+F+  FS  L  E    G+ VQ+V PF+V TKL A  R P +  P  E +V+SA+ TVG +  T G L H+I G I  S +P+  +I +G
Sbjct:   56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL-AKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAISLG 302
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. TrEMBL
Match: G1TGT5 (Hydroxysteroid 17-beta dehydrogenase 12 OS=Oryctolagus cuniculus OX=9986 GN=HSD17B12 PE=3 SV=2)

HSP 1 Score: 188.734 bits (478), Expect = 2.264e-53
Identity = 111/245 (45.31%), Postives = 155/245 (63.27%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            G+WAVVTG+TDGIG+ Y  QLAK G+NV LISR + KL   S E+K+ +K++      DFAS  IY  ++  + GL+IGVLVNNVG+       F+DI +  +    +    + +V  M++++   M +R +G I+NISSAS   P+P+ TIYSATK+F+  FS  L+EE    GI VQ+V P++V TKL A  R P F  P  E FV+SAI+TVG +  T G L HS+ G I   +P ++ +KI
Sbjct:   50 GEWAVVTGSTDGIGKSYAEQLAKRGMNVVLISRSQDKLNQVSNEIKEKFKVETRTIAVDFASEDIYNKIETGLAGLEIGVLVNNVGMSYEYPEYFLDIPDLDNTIKKLININVLSVCKMTRLVLPRMVERSKGAILNISSASGTFPVPLLTIYSATKAFVDFFSQCLHEEYRSKGIFVQSVLPYYVATKL-AKIRKPTFDKPSSETFVKSAIKTVGLQSRTNGYLVHSLMGTIHSMLPSWVFVKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. TrEMBL
Match: A0A2G8LQ11 (Uncharacterized protein OS=Stichopus japonicus OX=307972 GN=BSL78_00675 PE=3 SV=1)

HSP 1 Score: 186.808 bits (473), Expect = 1.474e-52
Identity = 114/246 (46.34%), Postives = 159/246 (64.63%), Query Frame = 3 
Query:  216 KESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDI-DEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFIS 947
            K+ G W+VVTGATDGIG+ Y  QLA  GLNV L+SR E KL+  + E+   Y +       DF S S IYE++ +++ GL+IGVLVNNVG+  P    F ++ D    + G+IN+N L+A MM+ +I   M  RK+G+IINI+SA+   P P+ T+YS+TKS+L  FS ALN E S  G++VQ+V P+FV +KL +  R   F +P    +V+SA+ TVG E  TFG   H++QG +V  +P  IS
Sbjct:   50 KKYGSWSVVTGATDGIGKAYAEQLAAKGLNVVLMSRTESKLDAVASEIASKYNVQTKVIAVDFTSGSEIYENIGKQLDGLEIGVLVNNVGMSYPYPLYFHELEDPEKLIQGMINVNCLAATMMTYLIVPSMLSRKKGLIINIASAAGSLPTPLLTVYSSTKSYLDFFSRALNVEYSSKGLIVQSVMPYFVVSKL-SKIRRSSFTVPTATSYVKSALATVGNETRTFGCFVHNLQGAVVSFVPEVIS 294
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. TrEMBL
Match: A0A2R9C3H2 (Hydroxysteroid 17-beta dehydrogenase 12 OS=Pan paniscus OX=9597 GN=HSD17B12 PE=3 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 9.699e-52
Identity = 110/274 (40.15%), Postives = 168/274 (61.31%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            Y+ + I +S+F    +        +    G+WAVVTG+TDGIG+ Y  +LAK G+ V LISR + KL+  S E+K+ +K++      DFAS  IY+ +K  + GL+IG+LVNNVG+       F+D+ +  ++   +    + +V  M++++   M +R +G I+NISS S + P+P+ TIYSATK+F+  FS  L+EE    G+ VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H++ G I+ ++P +I +KI
Sbjct:   21 YLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTALAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL-AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. TrEMBL
Match: H2Q3G0 (HSD17B12 isoform 2 OS=Pan troglodytes OX=9598 GN=HSD17B12 PE=2 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 9.699e-52
Identity = 110/274 (40.15%), Postives = 168/274 (61.31%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKI 956
            Y+ + I +S+F    +        +    G+WAVVTG+TDGIG+ Y  +LAK G+ V LISR + KL+  S E+K+ +K++      DFAS  IY+ +K  + GL+IG+LVNNVG+       F+D+ +  ++   +    + +V  M++++   M +R +G I+NISS S + P+P+ TIYSATK+F+  FS  L+EE    G+ VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H++ G I+ ++P +I +KI
Sbjct:   21 YLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTALAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKL-AKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKI 293
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. TrEMBL
Match: A0A2K5RGY4 (Hydroxysteroid 17-beta dehydrogenase 12 OS=Cebus capucinus imitator OX=1737458 GN=HSD17B12 PE=3 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 1.336e-51
Identity = 107/244 (43.85%), Postives = 155/244 (63.52%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIK 953
            G+WAVVTG TDGIG+ Y  +LAK G+ V LISR + KL+  S E+K+ +K++      DFAS  IY+ ++  + GL+IG+LVNNVG+       F+DI +  ++   +    + +V  M++++   M +R +G I+NISSAS   P+PM TIYSATK+F+  FS  L+EE    GI VQ+V P+FV TKL A  R P    P  E FV+SAI+TVG +  T G L H++ G+I+  +P ++  K
Sbjct:   50 GEWAVVTGGTDGIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIETGLAGLEIGILVNNVGMAYEYPEHFLDIPDLDNMIKKMINVNILSVCKMTQLVLPGMIERAKGAILNISSASGSHPVPMLTIYSATKAFVDFFSRCLHEEYRSKGIFVQSVLPYFVATKL-AKIRKPTLNTPSSETFVKSAIKTVGLQSRTNGYLIHAVMGLIISVLPSWLYFK 292
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Cavefish
Match: hsd17b12a (hydroxysteroid 17-beta dehydrogenase 12 [Source:NCBI gene;Acc:103027081])

HSP 1 Score: 158.688 bits (400), Expect = 2.519e-45
Identity = 91/231 (39.39%), Postives = 141/231 (61.04%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQG 914
            GKWAVVTGATDGIG+ Y  +LA+ G ++ LISR ++KL+  ++ L++ YK++      DF    IY  ++  + GL+IGVLVNNVGI  P    F+ I +  +    +    +++V  M++++   M  R +G+I+NISSAS + P+P+ T+YS+TK+F+  FS  L  E    GI++Q+V PFFV TK+    R P    P  + +V + + TVG +  T G   H++ G
Sbjct:   48 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRTQEKLDDVAQSLERRYKVETKTVAVDFGQVDIYPKIETALSGLEIGVLVNNVGISYPYPEFFLHIPDLDNFINTMINVNITSVCQMTRLVLPRMEARAKGVILNISSASGMYPVPLLTVYSSTKAFVDFFSRGLQAEYKSKGIIIQSVLPFFVATKM-TKIRKPTLDKPTPDRYVAAELTTVGLQDQTNGYFPHAVMG 277
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Cavefish
Match: hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:NCBI gene;Acc:103031519])

HSP 1 Score: 154.836 bits (390), Expect = 6.119e-44
Identity = 96/263 (36.50%), Postives = 158/263 (60.08%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGI---QQP-VVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQSNLKLR 1001
            GKWAV+TG +DGIG+ Y ++LA+ GLNV +ISR ++KL+  ++E++   +  V    ADF  + IY  ++E ++GLDIG+LVNNVGI   Q P ++ +  +++E  +     N+  +  V M  I+   M +R RGI++N+SS  +  P P   +Y+A+K+F+  FS  L  E    GIL+Q+V PF V T +    + P       EEFV +++  + T   T+GS++HSI G ++++IP ++     +   ++FQ  +K R
Sbjct:   47 GKWAVITGGSDGIGKAYAQELARRGLNVVIISRTKEKLDGVAREIELKTEAKVRAIAADFTKDDIYRDIEENIEGLDIGLLVNNVGILPTQLPCILLETANLEEKINQVINCNVKTM--VKMCHIVLPGMVERGRGIVLNVSSGIAKIPCPTYALYAASKAFVERFSQGLLAEYRSSGILIQSVSPFGVSTTMTGHPK-PDLITFTAEEFVRNSLMYLKTGEQTYGSVRHSILGWVIQAIPTWVLRS--EAFHQHFQEYVKRR 304
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Cavefish
Match: hsd17b12b (very-long-chain 3-oxoacyl-CoA reductase-B-like [Source:NCBI gene;Acc:103024613])

HSP 1 Score: 153.295 bits (386), Expect = 3.419e-43
Identity = 90/239 (37.66%), Postives = 146/239 (61.09%), Query Frame = 3 
Query:  219 ESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSI 932
            E G WAVVTGATDGIG+ Y  +LA+ G ++ LISR ++KL+  SK ++  YK+      ADF    IY  ++  +  L IG+LVNNVG+       F+++    ++   +    +S+V  M++++   M +R +G+I+NISSAS + P+P+ T+YS++K+F+  FS AL+ E    G+++Q+V PF+V TKL +  +     +P  E +V S I TVG +  T G L H++ G +  ++
Sbjct:   49 ELGAWAVVTGATDGIGKAYAEELARRGFSIVLISRTQEKLDEVSKAIESKYKVQTKTISADFGCVDIYPKIQAGLANLQIGILVNNVGVSYSYPEFFLNVPNLDNVISSMININISSVCQMTRLVLPGMVERSKGVILNISSASGMYPVPLLTLYSSSKAFVDFFSRALDAEYKSKGVIIQSVLPFYVTTKL-SKIKRASLDIPTPERYVRSQISTVGLQNQTNGYLPHAVMGWVTTAL 286
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Cavefish
Match: hsd20b2 (very-long-chain 3-oxoacyl-CoA reductase-like [Source:NCBI gene;Acc:103033448])

HSP 1 Score: 152.14 bits (383), Expect = 1.169e-42
Identity = 100/238 (42.02%), Postives = 144/238 (60.50%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADF-ASNSIYESLKERMKGLDIGVLVNNVGIQ-QPVVCDFIDI-DEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGI 917
            +++ G+WAVVTGAT GIGR Y  +LA+ GL++ LISR E+KL  T+KE++  Y+      QADF    SIY ++ +++KGL+IG+LVNNV +        F+D+ D    ++ +IN NILS   M+++I   M +R  G+IIN+SS ++  P PM  +YSATK F+T+FS  L+ E    GI VQ V PF V T +     +    +   E F   A+ TVG    T G L H++Q I
Sbjct:   49 VRKFGQWAVVTGATSGIGRAYALELARRGLDIVLISRSEEKLLQTAKEIESQYRRQTRIIQADFTGGESIYPAIAQQLKGLEIGILVNNVAMNYAEEFAHFLDVPDSEQRITQVINCNILSVTQMTRVILPHMVERGSGLIINLSSEAASKPQPMLALYSATKIFVTYFSRCLHSEYRSRGITVQCVAPFVVSTNMTNNVPVSP-LVKSAESFARDALNTVGYSSFTSGCLTHALQNI 285
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Cavefish
Match: hsd17b12a (hydroxysteroid 17-beta dehydrogenase 12 [Source:NCBI gene;Acc:103027081])

HSP 1 Score: 150.599 bits (379), Expect = 2.985e-42
Identity = 90/230 (39.13%), Postives = 137/230 (59.57%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQG 914
            GKWAVVTGATDGIG+ Y  +LA+ G ++ LISR ++KL+  ++ L++ YK++      DF    IY  ++  + GL+IGVLVNNVGI  P    F+ I +  +    +    +++V   K +      R +G+I+NISSAS + P+P+ T+YS+TK+F+  FS  L  E    GI++Q+V PFFV TK+    R P    P  + +V + + TVG +  T G   H++ G
Sbjct:   48 GKWAVVTGATDGIGKSYAEELARRGFSMMLISRTQEKLDDVAQSLERRYKVETKTVAVDFGQVDIYPKIETALSGLEIGVLVNNVGISYPYPEFFLHIPDLDNFINTMINVNITSVCQFKPLFPHF--RAKGVILNISSASGMYPVPLLTVYSSTKAFVDFFSRGLQAEYKSKGIIIQSVLPFFVATKM-TKIRKPTLDKPTPDRYVAAELTTVGLQDQTNGYFPHAVMG 274
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Sea Lamprey
Match: hsd17b12b (hydroxysteroid (17-beta) dehydrogenase 12b [Source:NCBI gene;Acc:322626])

HSP 1 Score: 131.339 bits (329), Expect = 2.988e-36
Identity = 90/242 (37.19%), Postives = 138/242 (57.02%), Query Frame = 3 
Query:  234 AVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADF-ASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIK 953
            +VVTGATDGIG+ Y  Q+ K  L + L+           +E+ + +K++      DF AS  IY  +   ++ L +GVLVNNVGI       F+DI     +   I    + +V+ M++II   M +RK G+IINISS S+L P+P+ ++YSATK F+  FS  LN E    GI+VQ+V PF+V++ + +  +     MP  E F  SA+ TVG +  T+G L H++Q  +   +P  +++K
Sbjct:    1 SVVTGATDGIGKAYVEQMLKTDLPLRLVVCSSHNCAQIVREMSERFKVETKTVAVDFTASEEIYPKVLAALRDLPVGVLVNNVGISYTYPEYFLDIPNLDDMIKNILNVNVLSVLKMTQIILPGMLERKGGVIINISSGSALFPVPLLSLYSATKVFVDFFSRGLNTEYKSKGIIVQSVLPFYVKSNM-SRIQRATLNMPEAETFACSALATVGRQSRTYGYLPHALQAWLSNMVPTCLAMK 241
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Sea Lamprey
Match: hsd17b12b (hydroxysteroid (17-beta) dehydrogenase 12b [Source:NCBI gene;Acc:322626])

HSP 1 Score: 122.479 bits (306), Expect = 6.457e-33
Identity = 88/243 (36.21%), Postives = 139/243 (57.20%), Query Frame = 3 
Query:  234 AVVTGATDGIGREYCRQLAKIGLNVFLISRD-EKKLEITSKELKKCYKIDVMYFQADF-ASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVM-MSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIK 953
            +VVTGATDGIG+ Y  Q++  G  +   ++    +L +    + + +K++      DF AS  IY  +   ++ L +GVLVNNVGI       F+DI     +   I    + +V+ M++II   M +RK G+IINISS S+L P+P+ ++YSATK F+  FS  LN E    GI+VQ+V PF+V++ + +  +     MP  E F  SA+ TVG +  T+G L H++Q  +   +P  +++K
Sbjct:    1 SVVTGATDGIGKAYVEQVSSRGRIMSPTAKSLPTRLGVAHVYVCERFKVETKTVAVDFTASEEIYPKVLAALRDLPVGVLVNNVGISYTYPEYFLDIPNLDDMIKNILNVNVLSVLKMTQIILPGMLERKGGVIINISSGSALFPVPLLSLYSATKVFVDFFSRGLNTEYKSKGIIVQSVLPFYVKSNM-SRIQRATLNMPEAETFACSALATVGRQSRTYGYLPHALQAWLSNMVPTCLAMK 242
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Sea Lamprey
Match: dhrsx (dehydrogenase/reductase (SDR family) X-linked [Source:ZFIN;Acc:ZDB-GENE-060620-2])

HSP 1 Score: 51.2174 bits (121), Expect = 1.464e-7
Identity = 34/98 (34.69%), Postives = 53/98 (54.08%), Query Frame = 3 
Query:  207 KLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCY---KIDVMYFQADFASNSIYESLKERMKG--LDIGVLVNNVGI 485
             L +++G+ AVVTG   GIG E  R+LA++G +V L S +EK+    ++ L+      K+D M+   D  S S       R +   L + +LVNN G+
Sbjct:   25 SLPRQTGRVAVVTGGGRGIGLETGRRLAELGAHVILASNNEKEGSEAAQALRSDTGNDKVDFMHL--DLRSLSSVRDFVNRFRSRKLPLHILVNNAGV 120
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010315.1 (pep scaffold:Pmarinus_7.0:GL479994:4152:14615:1 gene:ENSPMAG00000009341.1 transcript:ENSPMAT00000010315.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.6766 bits (117), Expect = 5.413e-7
Identity = 54/195 (27.69%), Postives = 92/195 (47.18%), Query Frame = 3 
Query:  240 VTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSK---ELKKCYKIDVMYFQADFASNSIYESLKERMKGLD----IGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGX-XXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYG-ILVQTVRPFFVQTKLIA 797
            VTGA+ GIG    R+LA+ G  + L +R E +L+   K   E     + D++    D    S +E+  + +  LD    + VLVNN G  Q  +  F+D D     +      +    +   ++   M+    G  ++ +SS + L+ +P++  Y A+K  +     AL  EL +Y  I + TV P  VQ+ +I+
Sbjct:   55 VTGASSGIGEALARELARCGCQLVLSARREAELQRVRKNCLEDSSLKESDILVLPMDVLDLSTHEACTKAV--LDRFGRVDVLVNNAGRSQRSL--FMDTDLCVYRTLFELNVLAPVSLARCVLPGMMAPGSHGGILLAVSSIAGLAGVPLSAGYCASKHAVQGAFNALRSELDEYPQITISTVCPGPVQSHIIS 245
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Yeast
Match: IFA38 (Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides [Source:SGD;Acc:S000000363])

HSP 1 Score: 120.168 bits (300), Expect = 1.672e-31
Identity = 84/240 (35.00%), Postives = 130/240 (54.17%), Query Frame = 3 
Query:  180 FLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASN--SIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXX----XXXXXXXXXXXAVMMSKIISAEMSQRK----RGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVG 869
            FLL +    K   ++GK+  +TGA+DGIG+E+ RQ+AK G N+ LISR + KLE   KEL+  + + V     D A +  S YES+KE    L I VLVNNVG    +   F++ +E               +++ ++  KI+    ++ K    RG+I+ + S   L P P+   YS +KSFL  +S +L  ELSK  I V+ +  + V T  ++  R     +P  ++FV+S +R+VG
Sbjct:   47 FLLPAVNFDKYGAKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKELRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLV-TSSMSKIRRSSLMIPNPQQFVKSTLRSVG 285
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Nematostella
Match: EDO41444 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4B0])

HSP 1 Score: 161.384 bits (407), Expect = 9.428e-47
Identity = 100/251 (39.84%), Postives = 149/251 (59.36%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNS-IYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLP-KFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKI 956
            +K  G WAVVTG TDGIGR Y  +LA  GLN+ LISR  +KL+   + ++  + +       DF  N+ +Y+ L E++  LDIG+LVNNVG+   ++  F D+ +      ++N+N LSAVMM+ I+   M  R+RG+++N+SS     P+P+ ++Y ATK+FL  FS  L+ E S  GI VQ VRP FV TK+      P   F P  +++VE A+ T+G E  T G   HS+   +  + IP ++  +I
Sbjct:   47 LKRYGSWAVVTGCTDGIGRCYAEKLAGRGLNIVLISRSLEKLKQVQQHIESQFSVQTKIIVKDFGGNAEVYQDLDEQLSNLDIGILVNNVGMAS-MINRFADL-KIEVCWKMLNVNALSAVMMTHIVLPGMLSRQRGVVVNVSSLVGSDPMPLMSVYCATKAFLDFFSSCLHSEYSSKGIFVQCVRPAFVATKMTGMRNKPGTAFTPTADQYVEQALGTIGVEQRTSGFWSHSLMAWVTFNIIPAWVRNRI 295
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Nematostella
Match: EDO41442 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4A6])

HSP 1 Score: 152.525 bits (384), Expect = 2.284e-44
Identity = 95/227 (41.85%), Postives = 141/227 (62.11%), Query Frame = 3 
Query:  237 VVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFA-SNSIYESLKERMKGLDIGVLVNNVGIQQ-PVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQ 911
            VVTG TDGIG+ +  QLA  G+N+ LISR ++KLE    E+K  YK+D      DF+ S  IYE L  ++ GLDIG+LVNNVG+   P   +F    +      +IN+N LS +MM+ II   M  R +G+++N+SS + L P P+ ++YS+ K+F+  FS  L++E S  GI+VQ+V P +V TK+ +  R P  F+P  +E+V+  + TVG +  T G   H++Q
Sbjct:    6 VVTGCTDGIGKSFAYQLAAQGINLILISRTKEKLENMEAEIKSAYKVDTRIIALDFSGSADIYEGLDVKLGGLDIGILVNNVGVSHYP---EFFTNMKREDCWKMINVNDLSVIMMTHIILPGMVSRGKGLVLNLSSGAGLEPRPLLSVYSSCKAFVDFFSCCLHDEYSGKGIIVQSVMPLYVATKM-SRIRKPNLFVPGPDEYVKQVLGTVGVQSRTNGCWSHALQ 228
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Nematostella
Match: EDO41770 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3H1])

HSP 1 Score: 64.3142 bits (155), Expect = 1.730e-11
Identity = 61/221 (27.60%), Postives = 117/221 (52.94%), Query Frame = 3 
Query:  141 IIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVF---LISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERM-KGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKL 791
            IIV ++F+++ ++ L++S+  +K ++   K+ ++TG   G G+E    L  +G++V    L +R E++L+       + +++DV   +       +Y +L+E +  G  +  +VNN GI      D+I ++    ++ I    +   V ++K     + +R RG I+N++S +    LP A+ YS +K     FS A+  EL+ +GI V  V P F +TK+
Sbjct:   17 IIVLLVFTLWIFRKLVKSDCPIKDLES--KYVLITGCDSGFGQETAILLDSLGVHVIATCLTARGEQELQKECCGRVRTFRLDVTKSKE---VQEVYRALQEELPHGTGLWGVVNNAGIAGVGPVDWIPVERFKHVADINLWGL---VDVTKTF-LPLVKRARGRIVNVTSIAGRFTLPFASPYSVSKYGAEAFSDAIRRELAPFGISVSIVEPGFFRTKM 228
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Nematostella
Match: EDO38087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDX1])

HSP 1 Score: 62.003 bits (149), Expect = 4.635e-11
Identity = 63/194 (32.47%), Postives = 103/194 (53.09%), Query Frame = 3 
Query:  222 SGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELK--KCYKIDVMYFQADFASNSIYESLKERMKGL-DIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEM-SQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKL 791
            SGK A+VTGA  GIGR   + L K G +V  +SR +  L+    E    + + IDV               +++ +KGL DI +LVNN G+ +  +  F DI E      +  +N+ +A+ +++ ++ +M +Q   G I+N+SS +S +PL   T+Y A+K+ L   +  +  EL K+ I V +V P  V T +
Sbjct:    6 SGKRALVTGAGKGIGRCTAKALVKCGADVVALSRTQSDLDSLKAESPSIQTHHIDVQN----------TSDVRDLIKGLGDIHLLVNNAGVGRLHL--FEDI-EPEDYDIVFGVNVKAALFVAQAVARKMKAQGSGGAIVNVSSQASQAPLMEHTLYCASKAALDMITKVMALELGKHKIRVNSVNPTVVLTDM 186
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Nematostella
Match: EDO33036 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STD1])

HSP 1 Score: 58.151 bits (139), Expect = 9.112e-10
Identity = 63/204 (30.88%), Postives = 95/204 (46.57%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERM----KGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFM 824
            GK A+VT +TDGIG    +QL K G  V + SR +  + I +    +   IDVM            ++L  R      G+DI  LV+N     PV    +   E  +   I  +N+ ++ ++SK +   M +R  G I+ ISS     PL     YS +K+ L   + AL +E +  GI V  V P  ++T+  AA R  +  M
Sbjct:   13 GKVAIVTASTDGIGLAIAQQLGKDGAKVVVSSRKQDNV-IKAANFLENEGIDVMGVMCHVGKPEHRQNLINRTINHFGGIDI--LVSNA-ATNPVFGPLLQTTE-DAWDKIFEVNVKASFLLSKDVIPHMEKRGGGNIVYISSIGGYQPLQGLGAYSISKTTLLGLTKALADECADIGIRVNCVAPGVIKTRFSAAVRRGRDKM 211
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Medaka
Match: hsd17b12a (very-long-chain 3-oxoacyl-CoA reductase-A [Source:NCBI gene;Acc:101163971])

HSP 1 Score: 162.925 bits (411), Expect = 1.099e-46
Identity = 101/266 (37.97%), Postives = 157/266 (59.02%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQG-IIVRSIPLFISIKIGKMIFRYFQSNL----KLRE 1004
            GKWAVVTGATDGIG+ Y  +LA+ G  + LISR ++KL+  +K L++ + ++      DF    IY  ++  + GL+IGVLVNNVG+       +++I +  +    +    +++V  M++++   M  R +G+I+NISSAS + PLP+ T+YSATK+F+  FS  L EE  + GI++Q+V PFFV TK+    R P    P  E +V + + TVG +  T G   H++ G +  + +P  I I +G  + R  +S      KLRE
Sbjct:   56 GKWAVVTGATDGIGKSYAEELARRGFAMMLISRSQEKLDDVAKSLEEQFGVETKTIAVDFGKTDIYPKIEAGLVGLEIGVLVNNVGVSYHYPEYYLNIPDLDNFLTNMINVNMTSVCQMTRLVLPGMVSRAKGVILNISSASGMYPLPLLTVYSATKAFMDFFSRGLQEEYRRQGIIIQSVLPFFVATKM-TRIRKPTLDKPTPERYVAAELTTVGLQNQTNGYFPHAVMGWVTTKLVPTSIVIFLGASMNRVQRSGYLHRRKLRE 320
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Medaka
Match: hsd17b12b (very-long-chain 3-oxoacyl-CoA reductase-B [Source:NCBI gene;Acc:101160884])

HSP 1 Score: 153.68 bits (387), Expect = 2.519e-43
Identity = 93/237 (39.24%), Postives = 143/237 (60.34%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAV-MMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSI 932
            GKWAVVTGATDGIG+ Y  +LA+ G ++ LISR ++KL+  SK +     ++      DF+S  IY  ++  + GL+IGVLVNNVGI       F+++    +    +    +++V  M++++   M +RK+G I+NISSAS + P+P+ TIYSA+K+F+  FS  L  E    GI++Q+V PFFV TKL +  R      P  + +V + I TVG +  T G L H++ G +  ++
Sbjct:   56 GKWAVVTGATDGIGKAYAEELARRGFSIVLISRSQEKLDEVSKAIAGKCGVETKTIAVDFSSVDIYPKIEAGLAGLEIGVLVNNVGISYSHPEFFLNVPNLDTFIDTMVNINITSVCQMTRLVLPRMVERKKGAILNISSASGMYPVPLLTIYSASKAFVDFFSRGLQAEYKSKGIIIQSVLPFFVATKL-SKIRRATLDKPNPDRYVAAEINTVGLQTQTNGYLPHAVMGWVTTAL 291
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Medaka
Match: hsd17b12b (very-long-chain 3-oxoacyl-CoA reductase-B [Source:NCBI gene;Acc:101160884])

HSP 1 Score: 151.754 bits (382), Expect = 9.100e-43
Identity = 92/236 (38.98%), Postives = 138/236 (58.47%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSI 932
            GKWAVVTGATDGIG+ Y  +LA+ G ++ LISR ++KL+  SK +     ++      DF+S  IY  ++  + GL+IGVLVNNVGI       F+++    +              M++++   M +RK+G I+NISSAS + P+P+ TIYSA+K+F+  FS  L  E    GI++Q+V PFFV TKL +  R      P  + +V + I TVG +  T G L H++ G +  ++
Sbjct:   56 GKWAVVTGATDGIGKAYAEELARRGFSIVLISRSQEKLDEVSKAIAGKCGVETKTIAVDFSSVDIYPKIEAGLAGLEIGVLVNNVGISYSHPEFFLNVPNLDT--------------MTRLVLPRMVERKKGAILNISSASGMYPVPLLTIYSASKAFVDFFSRGLQAEYKSKGIIIQSVLPFFVATKL-SKIRRATLDKPNPDRYVAAEINTVGLQTQTNGYLPHAVMGWVTTAL 276
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Medaka
Match: hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:NCBI gene;Acc:100125485])

HSP 1 Score: 138.272 bits (347), Expect = 1.835e-37
Identity = 88/244 (36.07%), Postives = 147/244 (60.25%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVV----CDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPL 938
            G+WAVVTGA++GIGR Y   LA+ G+N+ ++SR +  L+  +KE+       V    ADF   +I+  ++E++K L +G+LVNNVGI    +     +  D+D++ +     N+  +  V M ++I  +M +R++G+I+NISS  +  P P+ T+Y+A+K F+  FS  L  E    GIL+Q V PF V T++ A ++ P    F+P  E+FV+++++ +     T GS+ H + G I++ IPL
Sbjct:   51 GEWAVVTGASEGIGRAYAFALAERGMNIVIMSRTKSTLDQVAKEISNSTGQKVRVIIADFTDENIFSEIEEQLKDLCVGILVNNVGILPSFIPYRFLESEDLDQTITKVINCNVKTM--VKMCRMILPQMDKRRKGVIVNISSGIASVPFPLYTLYAASKIFVERFSQGLQAEYENRGILIQAVAPFGVCTRM-AGYQPPNRVTFLP--EDFVKNSLQYLRAGNKTHGSICHIVLGWILQCIPL 289
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Medaka
Match: hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3 [Source:NCBI gene;Acc:100125485])

HSP 1 Score: 138.658 bits (348), Expect = 2.474e-37
Identity = 88/244 (36.07%), Postives = 147/244 (60.25%), Query Frame = 3 
Query:  225 GKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVV----CDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPK--FFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPL 938
            G+WAVVTGA++GIGR Y   LA+ G+N+ ++SR +  L+  +KE+       V    ADF   +I+  ++E++K L +G+LVNNVGI    +     +  D+D++ +     N+  +  V M ++I  +M +R++G+I+NISS  +  P P+ T+Y+A+K F+  FS  L  E    GIL+Q V PF V T++ A ++ P    F+P  E+FV+++++ +     T GS+ H + G I++ IPL
Sbjct:   79 GEWAVVTGASEGIGRAYAFALAERGMNIVIMSRTKSTLDQVAKEISNSTGQKVRVIIADFTDENIFSEIEEQLKDLCVGILVNNVGILPSFIPYRFLESEDLDQTITKVINCNVKTM--VKMCRMILPQMDKRRKGVIVNISSGIASVPFPLYTLYAASKIFVERFSQGLQAEYENRGILIQAVAPFGVCTRM-AGYQPPNRVTFLP--EDFVKNSLQYLRAGNKTHGSICHIVLGWILQCIPL 317
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Planmine SMEST
Match: SMESG000075064.1 (SMESG000075064.1)

HSP 1 Score: 518.079 bits (1333), Expect = 0.000e+0
Identity = 288/293 (98.29%), Postives = 289/293 (98.63%), Query Frame = 3 
Query:  126 WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQSNLKLRE 1004
            WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQP VCDFIDIDESFSLSGIININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMA IYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAA+RLPKFFM PVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQS LKLRE
Sbjct:   12 WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPFVCDFIDIDESFSLSGIININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMAAIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAYRLPKFFMSPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQSGLKLRE 304
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Planmine SMEST
Match: SMESG000075064.1 (SMESG000075064.1)

HSP 1 Score: 518.079 bits (1333), Expect = 0.000e+0
Identity = 288/293 (98.29%), Postives = 289/293 (98.63%), Query Frame = 3 
Query:  126 WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQSNLKLRE 1004
            WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQP VCDFIDIDESFSLSGIININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMA IYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAA+RLPKFFM PVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQS LKLRE
Sbjct:   11 WLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPFVCDFIDIDESFSLSGIININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMAAIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAYRLPKFFMSPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQSGLKLRE 303
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Planmine SMEST
Match: SMESG000062708.1 (SMESG000062708.1)

HSP 1 Score: 147.902 bits (372), Expect = 3.083e-41
Identity = 107/296 (36.15%), Postives = 165/296 (55.74%), Query Frame = 3 
Query:  138 YIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXX--XXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYG----ILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRS-IPLFISIKIGKMIFRYFQSNLKLRE 1004
            Y +V     ++ YK    S      IK  G W VVTG TDGIG+ +C +LAK   N+ LISR+E+KL I S+EL + ++I V Y  ADF    IY+ +   ++GL +G+L+NNVG   P   DF   D         +++ N LS V+M++I+      ++ G+I+N+SSASS   +P+ T+Y++ KS L  F+  L  E+   G    I VQ   PF+V +KL +  +  KF +P  EEF +S +R +     +FG + HS +   +   IP F++    K++ R  +S +KLR+
Sbjct:   28 YHVVYFAAVLWTYKLKPVSESKFDKIKSYGNWVVVTGTTDGIGKCFCEKLAKRKFNLILISRNEEKLLIQSQELMEKFRISVKYITADFRKTKIYDHIAASVEGLPVGLLINNVGAAYPSP-DFYTADHLSDRDFIDMLHCNCLSTVLMTRILLKSCMLKQGGVIVNMSSASSFLEIPVLTMYASCKSLLNCFTNCLQAEIDAQGAGDRIFVQNFTPFWVISKL-SGIKTRKFLVPTAEEFTDSCLRQLCENHQSFGYITHSYENWFLNKLIPKFLN----KVLVR--RSMMKLRD 315
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Planmine SMEST
Match: SMESG000077527.1 (SMESG000077527.1)

HSP 1 Score: 126.331 bits (316), Expect = 3.159e-33
Identity = 87/246 (35.37%), Postives = 142/246 (57.72%), Query Frame = 3 
Query:  213 IKESGKWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYFQADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFI--DIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEFVESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFI 944
            I + G W VVTGATDGIG+ +   LAK   N+ LISR  +KLE    E+ + + +D+    ADF+   IY+ ++  +K L+IG+L+NNVG+      D++  +I+   S+  I+N N LS V+M++++       K G I+N+SSASS+ P+P  ++Y ++K+F+  F+ ++  E  +  +  Q V PFFV TK+ +  R P    P    +  S +  +GT   T+G   H +QG  +  +P F+
Sbjct:   48 INKYGNWVVVTGATDGIGKAFAELLAKDKFNLVLISRSFEKLEKVKNEILEKHNVDIRIISADFSKLDIYDKIESEIKDLEIGLLINNVGMSSK-YPDYLTSEINSPDSVINILNCNCLSTVLMTRLLLKIRMADKGGFILNVSSASSMFPIPFLSVYGSSKAFINSFTRSMISEF-RNKVHFQNVAPFFVSTKM-SKLR-PSLTAPTPRNYANSVLNRLGTSTFTYGCFVHELQGWFIGLLPSFV 289
[Close]
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Planmine SMEST
Match: SMESG000079254.1 (SMESG000079254.1)

HSP 1 Score: 50.447 bits (119), Expect = 7.136e-7
Identity = 56/195 (28.72%), Postives = 95/195 (48.72%), Query Frame = 3 
Query:  228 KWAVVTGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSK--ELKKCYKID-VMYFQADFASNSIYESLKERM----KGLDIGVLVNNVGIQQPVVCDFIDIDEXXXXXXXXXXXXXXAVMMSKIISAEMSQRKRGXXXXXXXXXXXXPLPMATIYSATKSFLTHFSLALNEELSKYGILVQTVRPFFVQTKL 791
            K A++TGA+ GIG+       K+G N+ +  R+ + L  T K  EL K  +   ++ F AD  +    + L E+       LDI  L+NN G+   +  D I+  E  +   ++N+N+ S + ++ ++S  +  RK G I+N+SS +     P    Y  +K+ L  F+     +L+  G+ V  V P    T L
Sbjct:   10 KNALITGASSGIGKSTAELFFKLGANILITGRNLENLNDTIKLCELSKVNENQRIVAFTADLTNEEDVKKLAEKTLLEFPKLDI--LINNAGV---ISNDTIENVEMENFDSVMNMNLRSVIQLTNLLSPSLIDRK-GSIVNVSSVAGTRAFPNVMSYCISKAALEQFTKCTALDLASKGVRVNAVSPGVTVTNL 198
The following BLAST results are available for this feature:
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HSD17B128.526e-5540.15hydroxysteroid 17-beta dehydrogenase 12 [Source:HG... [more]
HSDL13.993e-4734.78hydroxysteroid dehydrogenase like 1 [Source:HGNC S... [more]
HSD17B38.540e-4136.84hydroxysteroid 17-beta dehydrogenase 3 [Source:HGN... [more]
HSD17B31.858e-3938.79hydroxysteroid 17-beta dehydrogenase 3 [Source:HGN... [more]
HSD17B129.182e-3734.67hydroxysteroid 17-beta dehydrogenase 12 [Source:HG... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stdh-29.875e-3837.07Putative steroid dehydrogenase 2 [Source:UniProtK... [more]
let-7671.461e-3638.91Very-long-chain 3-oxooacyl-coA reductase let-767 ... [more]
let-7671.461e-3638.91Very-long-chain 3-oxooacyl-coA reductase let-767 ... [more]
let-7672.906e-3638.91Very-long-chain 3-oxooacyl-coA reductase let-767 ... [more]
let-7671.868e-3535.77Very-long-chain 3-oxooacyl-coA reductase let-767 ... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG132843.142e-4839.46gene:FBgn0032614 transcript:FBtr0345747[more]
CG132843.142e-4839.46gene:FBgn0032614 transcript:FBtr0080926[more]
CG132844.441e-4839.46gene:FBgn0032614 transcript:FBtr0332333[more]
CG132845.167e-4839.46gene:FBgn0032614 transcript:FBtr0332334[more]
CG132845.167e-4839.46gene:FBgn0032614 transcript:FBtr0080927[more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsd20b22.696e-4742.74hydroxysteroid (20-beta) dehydrogenase 2 [Source:Z... [more]
hsd20b22.696e-4742.74hydroxysteroid (20-beta) dehydrogenase 2 [Source:Z... [more]
hsd17b12b3.861e-4737.90hydroxysteroid (17-beta) dehydrogenase 12b [Source... [more]
hsd17b31.240e-4638.84hydroxysteroid (17-beta) dehydrogenase 3 [Source:Z... [more]
hsd17b31.740e-4638.43hydroxysteroid (17-beta) dehydrogenase 3 [Source:Z... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsd17b125.094e-4942.34hydroxysteroid (17-beta) dehydrogenase 12 [Source:... [more]
hsd17b121.857e-4842.51hydroxysteroid (17-beta) dehydrogenase 12 [Source:... [more]
hsd17b123.039e-4641.70hydroxysteroid (17-beta) dehydrogenase 12 [Source:... [more]
hsd17b125.948e-4440.89hydroxysteroid (17-beta) dehydrogenase 12 [Source:... [more]
ENSXETT00000003444.12.719e-4037.82estradiol 17-beta-dehydrogenase 12-B-like [Source:... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hsd17b128.376e-4840.82hydroxysteroid (17-beta) dehydrogenase 12 [Source:... [more]
Hsdl12.386e-4435.38hydroxysteroid dehydrogenase like 1 [Source:MGI Sy... [more]
Hsdl14.624e-4435.38hydroxysteroid dehydrogenase like 1 [Source:MGI Sy... [more]
Hsd17b31.948e-3837.76hydroxysteroid (17-beta) dehydrogenase 3 [Source:M... [more]
Hsd17b31.948e-3837.76hydroxysteroid (17-beta) dehydrogenase 3 [Source:M... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q53GQ0|DHB12_HUMAN4.094e-5440.15Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sa... [more]
sp|Q4R5G7|DHB12_MACFA3.340e-5239.78Very-long-chain 3-oxoacyl-CoA reductase OS=Macaca ... [more]
sp|Q5E9H7|DHB12_BOVIN9.990e-5040.24Very-long-chain 3-oxoacyl-CoA reductase OS=Bos tau... [more]
sp|Q6P7R8|DHB12_RAT1.718e-4841.39Very-long-chain 3-oxoacyl-CoA reductase OS=Rattus ... [more]
sp|Q28IU1|DHB12_XENTR2.699e-4842.34Very-long-chain 3-oxoacyl-CoA reductase OS=Xenopus... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G1TGT52.264e-5345.31Hydroxysteroid 17-beta dehydrogenase 12 OS=Oryctol... [more]
A0A2G8LQ111.474e-5246.34Uncharacterized protein OS=Stichopus japonicus OX=... [more]
A0A2R9C3H29.699e-5240.15Hydroxysteroid 17-beta dehydrogenase 12 OS=Pan pan... [more]
H2Q3G09.699e-5240.15HSD17B12 isoform 2 OS=Pan troglodytes OX=9598 GN=H... [more]
A0A2K5RGY41.336e-5143.85Hydroxysteroid 17-beta dehydrogenase 12 OS=Cebus c... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsd17b12a2.519e-4539.39hydroxysteroid 17-beta dehydrogenase 12 [Source:NC... [more]
hsd17b36.119e-4436.50hydroxysteroid 17-beta dehydrogenase 3 [Source:NCB... [more]
hsd17b12b3.419e-4337.66very-long-chain 3-oxoacyl-CoA reductase-B-like [So... [more]
hsd20b21.169e-4242.02very-long-chain 3-oxoacyl-CoA reductase-like [Sour... [more]
hsd17b12a2.985e-4239.13hydroxysteroid 17-beta dehydrogenase 12 [Source:NC... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
hsd17b12b2.988e-3637.19hydroxysteroid (17-beta) dehydrogenase 12b [Source... [more]
hsd17b12b6.457e-3336.21hydroxysteroid (17-beta) dehydrogenase 12b [Source... [more]
dhrsx1.464e-734.69dehydrogenase/reductase (SDR family) X-linked [Sou... [more]
ENSPMAT00000010315.15.413e-727.69pep scaffold:Pmarinus_7.0:GL479994:4152:14615:1 ge... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
IFA381.672e-3135.00Microsomal beta-keto-reductase; contains oleate re... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO414449.428e-4739.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414422.284e-4441.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO417701.730e-1127.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO380874.635e-1132.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO330369.112e-1030.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsd17b12a1.099e-4637.97very-long-chain 3-oxoacyl-CoA reductase-A [Source:... [more]
hsd17b12b2.519e-4339.24very-long-chain 3-oxoacyl-CoA reductase-B [Source:... [more]
hsd17b12b9.100e-4338.98very-long-chain 3-oxoacyl-CoA reductase-B [Source:... [more]
hsd17b31.835e-3736.07hydroxysteroid 17-beta dehydrogenase 3 [Source:NCB... [more]
hsd17b32.474e-3736.07hydroxysteroid 17-beta dehydrogenase 3 [Source:NCB... [more]
back to top
BLAST of Very-long-chain 3-oxoacyl-CoA reductase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075064.10.000e+098.29SMESG000075064.1[more]
SMESG000075064.10.000e+098.29SMESG000075064.1[more]
SMESG000062708.13.083e-4136.15SMESG000062708.1[more]
SMESG000077527.13.159e-3335.37SMESG000077527.1[more]
SMESG000079254.17.136e-728.72SMESG000079254.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011844 ID=SMED30011844|Name=Very-long-chain 3-oxoacyl-CoA reductase|organism=Schmidtea mediterranea sexual|type=transcript|length=1121bp
GGACAGTTGTTTTTGAAATTCGAAAATTGTTTTATGAATTGTTATATTTT
GAATTAATTATTGCTCAGTCTTTATAAATCATATTAAGAAATATGATGAA
TATCATTGTTTTCATATTCATTTTTTGGCTTTTTCATTATATAATTGTTC
CAATCATATTTTCGATTTTTAAATATAAATTTCTATTGCAATCTAATAAG
CATGTAAAATTAATTAAAGAAAGTGGAAAATGGGCAGTAGTTACTGGTGC
AACAGATGGGATCGGCCGTGAGTATTGTCGGCAGTTGGCAAAAATTGGAT
TGAATGTTTTTCTTATAAGTAGAGATGAAAAGAAATTAGAAATAACTAGC
AAAGAATTAAAGAAATGTTATAAAATCGATGTGATGTATTTCCAAGCAGA
TTTTGCATCTAATTCAATTTATGAAAGTTTGAAAGAACGAATGAAAGGAT
TGGACATTGGAGTTTTAGTAAACAATGTAGGAATCCAGCAACCGGTTGTG
TGTGATTTTATTGATATTGACGAAAGCTTTTCTCTTAGTGGAATTATAAA
TATCAATATTTTGTCTGCCGTCATGATGTCAAAAATCATTTCCGCAGAAA
TGAGTCAACGAAAACGTGGAATTATCATCAACATTTCTTCTGCGTCTTCT
CTCTCTCCGCTACCAATGGCAACTATTTACAGCGCAACAAAATCATTCTT
AACTCATTTTTCTCTTGCGCTCAATGAAGAGTTGTCAAAATATGGAATAT
TAGTGCAAACAGTTCGTCCGTTTTTTGTTCAAACAAAATTAATAGCCGCA
TTTCGCCTGCCGAAATTTTTCATGCCGCCTGTGGAGGAATTTGTCGAGTC
GGCAATCAGGACTGTAGGAACCGAGGGCGACACATTTGGAAGTCTCCAGC
ATTCCATTCAAGGAATTATCGTTAGGAGTATTCCATTATTCATATCGATT
AAAATTGGGAAAATGATCTTTCGATATTTCCAAAGTAATTTGAAACTTCG
AGAATAATGCCGGATTTGCCTGATATTTGTTTTGTGTTGCTAATCTTGTC
GCTTTTTCTATTATTTGTTTGTTTCTTTTTTATAACGTTTTTATAATATA
AATAATTAAATAAATTTGGCA
back to top

protein sequence of SMED30011844-orf-1

>SMED30011844-orf-1 ID=SMED30011844-orf-1|Name=SMED30011844-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=305bp
MMNIIVFIFIFWLFHYIIVPIIFSIFKYKFLLQSNKHVKLIKESGKWAVV
TGATDGIGREYCRQLAKIGLNVFLISRDEKKLEITSKELKKCYKIDVMYF
QADFASNSIYESLKERMKGLDIGVLVNNVGIQQPVVCDFIDIDESFSLSG
IININILSAVMMSKIISAEMSQRKRGIIINISSASSLSPLPMATIYSATK
SFLTHFSLALNEELSKYGILVQTVRPFFVQTKLIAAFRLPKFFMPPVEEF
VESAIRTVGTEGDTFGSLQHSIQGIIVRSIPLFISIKIGKMIFRYFQSNL
KLRE*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000101muscle cell
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR036291NAD(P)-bd_dom_sf
IPR002347SDR_fam
IPR016040NAD(P)-bd_dom
Vocabulary: molecular function
TermDefinition
GO:0001968fibronectin binding
GO:0004303estradiol 17-beta-dehydrogenase activity
GO:0005515protein binding
GO:0005518collagen binding
GO:0008201heparin binding
GO:0016491oxidoreductase activity
GO:0016509long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:01023393-oxo-arachidoyl-CoA reductase activity
GO:01023403-oxo-behenoyl-CoA reductase activity
GO:01023413-oxo-lignoceroyl-CoA reductase activity
GO:01023423-oxo-cerotoyl-CoA reductase activity
Vocabulary: cellular component
TermDefinition
GO:0005578proteinaceous extracellular matrix
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006629lipid metabolic process
GO:0006633fatty acid biosynthetic process
GO:0006694steroid biosynthetic process
GO:0006703estrogen biosynthetic process
GO:0010811positive regulation of cell-substrate adhesion
GO:0030198extracellular matrix organization
GO:0035338long-chain fatty-acyl-CoA biosynthetic process
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002347Short-chain dehydrogenase/reductase SDRPRINTSPR00081GDHRDHcoord: 47..64
score: 40.58
coord: 196..215
score: 29.8
coord: 170..186
score: 34.61
coord: 120..131
score: 42.09
coord: 217..234
score: 30.34
IPR002347Short-chain dehydrogenase/reductase SDRPRINTSPR00080SDRFAMILYcoord: 176..184
score: 57.64
coord: 196..215
score: 30.68
coord: 120..131
score: 43.44
IPR002347Short-chain dehydrogenase/reductase SDRPFAMPF00106adh_shortcoord: 46..236
e-value: 2.8E-41
score: 141.1
NoneNo IPR availableGENE3DG3DSA:3.40.50.720coord: 39..272
e-value: 2.0E-48
score: 166.9
NoneNo IPR availablePIRSFPIRSF00012611-beta-HSD1coord: 1..301
e-value: 1.2E-83
score: 278.1
NoneNo IPR availablePANTHERPTHR43899FAMILY NOT NAMEDcoord: 6..298
NoneNo IPR availablePANTHERPTHR43899:SF9RE06583P-RELATEDcoord: 6..298
NoneNo IPR availableCDDcd0535617beta-HSD1_like_SDR_ccoord: 45..284
e-value: 7.74132E-83
score: 247.902
NoneNo IPR availableTMHMMTMhelixcoord: 176..198
NoneNo IPR availableTMHMMTMhelixcoord: 4..26
IPR036291NAD(P)-binding domain superfamilySUPERFAMILYSSF51735NAD(P)-binding Rossmann-fold domainscoord: 41..294