EH domain-containing protein 1

Overview
NameEH domain-containing protein 1
Smed IDSMED30011830
Length (bp)1879
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of EH domain-containing protein 1 (SMED30011830) t-SNE clustered cells

Violin plots show distribution of expression levels for EH domain-containing protein 1 (SMED30011830) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EH domain-containing protein 1 (SMED30011830) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EH domain-containing protein 1 (SMED30011830) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30011830

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30011830h1SMcG0014196 dd_Smed_v4_3205_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011830h1SMcG0014196 dd_Smed_v4_3205_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011830h1SMcG0014196 dd_Smed_v4_3205_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30011830h1SMcG0014196 dd_Smed_v4_3205_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of EH domain-containing protein 1 vs. Ensembl Human
Match: EHD4 (EH domain containing 4 [Source:HGNC Symbol;Acc:HGNC:3245])

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 275/477 (57.65%), Postives = 361/477 (75.68%), Query Frame = 2
Query:  119 KPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            KP +LL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ +   ST  PG A V D K PF+ L++FGN+FLNRF CS LPN VLKSI++ID+PGILSGEKQR+ RGYD+ QV+ WFA+RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W QPLQ  D+R+LF+ E ++L  D+++LP  AA+RK+NDLI+RARLAKVHA+IIS+LK+ MP +  KE KK+ELIS L E++ +L   +Q+S GDFP+VK+MQEQL + DF++  SLK KLI+ VDNML+  I  L+  I Q  EE     + V+GGAF+    E PF Q       +G  E  WVV + +  Y+E+F +L P NG ++G   +  ++ +KLP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELP+ LP HL+PPS
Sbjct:   61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGST--PGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQ--EETSTPTQLVQGGAFDGTT-EGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPS 532          
BLAST of EH domain-containing protein 1 vs. Ensembl Human
Match: EHD1 (EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242])

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 271/479 (56.58%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   71 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQVVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSK 544          
BLAST of EH domain-containing protein 1 vs. Ensembl Human
Match: EHD1 (EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 271/479 (56.58%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQVVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSK 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Human
Match: EHD1 (EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 271/479 (56.58%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQVVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSK 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Human
Match: EHD3 (EH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:3244])

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 274/482 (56.85%), Postives = 361/482 (74.90%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M  D     +IPG A V D K PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  K+ KK+EL+++L E++ R+   HQ+S GDFP +K MQ+QL   DFS+   LK KL++ VD+MLA DI  L+  + Q  EE+    + VKGGAF       PF         +G  +  WVV   +  Y+EIF +L P +G +TG   +  ++++KLP  VL ++WKL+D+D DG LD DEFALA++L+K+KL G ELPNELP HL+PPSK  +
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDM--EGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQ--EESQRPIQMVKGGAFEG-TLHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKV 533          
BLAST of EH domain-containing protein 1 vs. Ensembl Celegans
Match: rme-1 (Receptor Mediated Endocytosis [Source:UniProtKB/TrEMBL;Acc:Q86S80])

HSP 1 Score: 603.979 bits (1556), Expect = 0.000e+0
Identity = 290/486 (59.67%), Postives = 371/486 (76.34%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQ-----ITEENDFGKKTVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I K+KKK++LI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+         N     TV+GGAF+   E E P  F R E   +KG  E  WVV   ++  +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK
Sbjct:  288 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDLNRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKDKKKKDLIQNLDKIYEQLQREHNISPGDFPDVNKMREKLQTQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPFGFGRGE-GFDKGADEAEWVVSRERTTADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSK 770          
BLAST of EH domain-containing protein 1 vs. Ensembl Celegans
Match: rme-1 (Receptor Mediated Endocytosis [Source:UniProtKB/TrEMBL;Acc:Q86S80])

HSP 1 Score: 603.979 bits (1556), Expect = 0.000e+0
Identity = 290/486 (59.67%), Postives = 371/486 (76.34%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQ-----ITEENDFGKKTVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I K+KKK++LI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+         N     TV+GGAF+   E E P  F R E   +KG  E  WVV   ++  +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK
Sbjct:  288 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDLNRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKDKKKKDLIQNLDKIYEQLQREHNISPGDFPDVNKMREKLQTQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPFGFGRGE-GFDKGADEAEWVVSRERTTADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSK 770          
BLAST of EH domain-containing protein 1 vs. Ensembl Celegans
Match: rme-1 (Receptor Mediated Endocytosis [Source:UniProtKB/TrEMBL;Acc:Q86S80])

HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0
Identity = 289/490 (58.98%), Postives = 370/490 (75.51%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQ-----ITEENDFGKKTVKGGAFNAINE-ENPF------QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I K+KKK++LI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+         N     TV+GGAF+   E E PF       R     +KG  E  WVV   ++  +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK
Sbjct:  288 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDLNRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKDKKKKDLIQNLDKIYEQLQREHNISPGDFPDVNKMREKLQTQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPFGFGRYDARWGEGFDKGADEAEWVVSRERTTADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSK 775          
BLAST of EH domain-containing protein 1 vs. Ensembl Celegans
Match: rme-1 (Receptor Mediated Endocytosis [Source:UniProtKB/TrEMBL;Acc:Q86S80])

HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0
Identity = 289/490 (58.98%), Postives = 370/490 (75.51%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQ-----ITEENDFGKKTVKGGAFNAINE-ENPF------QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I K+KKK++LI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+         N     TV+GGAF+   E E PF       R     +KG  E  WVV   ++  +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK
Sbjct:  288 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDLNRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKDKKKKDLIQNLDKIYEQLQREHNISPGDFPDVNKMREKLQTQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPFGFGRYDARWGEGFDKGADEAEWVVSRERTTADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSK 775          
BLAST of EH domain-containing protein 1 vs. Ensembl Celegans
Match: rme-1 (Receptor Mediated Endocytosis [Source:UniProtKB/TrEMBL;Acc:Q86S80])

HSP 1 Score: 600.512 bits (1547), Expect = 0.000e+0
Identity = 290/486 (59.67%), Postives = 371/486 (76.34%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQ-----ITEENDFGKKTVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I K+KKK++LI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+         N     TV+GGAF+   E E P  F R E   +KG  E  WVV   ++  +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK
Sbjct:  110 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDLNRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKDKKKKDLIQNLDKIYEQLQREHNISPGDFPDVNKMREKLQTQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPFGFGRGE-GFDKGADEAEWVVSRERTTADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSK 592          
BLAST of EH domain-containing protein 1 vs. Ensembl Fly
Match: Past1 (gene:FBgn0016693 transcript:FBtr0082654)

HSP 1 Score: 585.489 bits (1508), Expect = 0.000e+0
Identity = 285/481 (59.25%), Postives = 372/481 (77.34%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEEN--PFQRVEI-AINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +M+ D+    VIPG A V D K  F+ L+K+GN+FLNRFQCS + + VL +I+++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEF+R+I+ LK +D+KIRIILNKADMI+ QQLM+VYGAL+WSLGKVL TPEV RV++GS+WDQPL+FD +R+LF+ EE++L  DL++LP NAA+RK+NDLI+RARLAKVHAFII+ L+++MP +  K+ KK++LI +L +V+ R+   H +S GDFP +K MQE L   DF++  SLK  L+D VDNMLA DI  L++ IPQ  E        VKGGAF  + +++  PF  ++   I+ G  E  W+  + +   + IFN L P +G ++G   +  L+K+KLP  VLS++WKLSD+DGDGFLD DEFALA +L+ +KL G ELP  LP+HL+PPSK
Sbjct:   60 AKPMILLVGQYSTGKTTFIRYLLERDFPGIRIGPEPTTDRFIAVMYDDK--EGVIPGNALVVDPKKQFRPLSKYGNAFLNRFQCSSVASPVLNAISIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFRRSIEALKGHDDKIRIILNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDQPLRFDANRRLFEDEEQDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIAELRKDMPSVFGKDSKKKDLIKNLGQVYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSLKPHLLDIVDNMLAKDIARLMEMIPQ-EEMTMVADPIVKGGAFEGVIDDHVSPFGYMKGEGIDAGYGEHEWICNKDKPRTDGIFNGLGPVDGKISGATAKQELIKSKLPNSVLSKIWKLSDVDGDGFLDSDEFALALHLINVKLEGCELPTVLPEHLVPPSK 537          
BLAST of EH domain-containing protein 1 vs. Ensembl Fly
Match: Past1 (gene:FBgn0016693 transcript:FBtr0082655)

HSP 1 Score: 584.719 bits (1506), Expect = 0.000e+0
Identity = 285/481 (59.25%), Postives = 372/481 (77.34%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEEN--PFQRVEI-AINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +M+ D+    VIPG A V D K  F+ L+K+GN+FLNRFQCS + + VL +I+++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEF+R+I+ LK +D+KIRIILNKADMI+ QQLM+VYGAL+WSLGKVL TPEV RV++GS+WDQPL+FD +R+LF+ EE++L  DL++LP NAA+RK+NDLI+RARLAKVHAFII+ L+++MP +  K+ KK++LI +L +V+ R+   H +S GDFP +K MQE L   DF++  SLK  L+D VDNMLA DI  L++ IPQ  E        VKGGAF  + +++  PF  ++   I+ G  E  W+  + +   + IFN L P +G ++G   +  L+K+KLP  VLS++WKLSD+DGDGFLD DEFALA +L+ +KL G ELP  LP+HL+PPSK
Sbjct:   54 AKPMILLVGQYSTGKTTFIRYLLERDFPGIRIGPEPTTDRFIAVMYDDK--EGVIPGNALVVDPKKQFRPLSKYGNAFLNRFQCSSVASPVLNAISIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFRRSIEALKGHDDKIRIILNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDQPLRFDANRRLFEDEEQDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIAELRKDMPSVFGKDSKKKDLIKNLGQVYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSLKPHLLDIVDNMLAKDIARLMEMIPQ-EEMTMVADPIVKGGAFEGVIDDHVSPFGYMKGEGIDAGYGEHEWICNKDKPRTDGIFNGLGPVDGKISGATAKQELIKSKLPNSVLSKIWKLSDVDGDGFLDSDEFALALHLINVKLEGCELPTVLPEHLVPPSK 531          
BLAST of EH domain-containing protein 1 vs. Ensembl Fly
Match: CG9297 (gene:FBgn0038181 transcript:FBtr0082827)

HSP 1 Score: 139.813 bits (351), Expect = 3.956e-34
Identity = 101/369 (27.37%), Postives = 180/369 (48.78%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFP--GIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIIS---HLKQNMPYLIRKEKKKQELISSLDEVFH---RLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQ--KLID-----------QVDNMLAVDIPILLQKIPQITE 1159
            +KP +L +G +S GK++ + YL + ++    +R G EP+   F ++M  ++  + V+ G     D    F GL KFG     R +   + + +L+ + +++ PGIL   KQ V R + +     WF  R D I L++D  KLD+  E +  +D LK  + + RIILNKAD +  ++L++V GAL+W++  ++S+ + P ++  S W  P Q     +L   +E   + DL+         KI    R A   + HA ++    +   N   L   +K+  + I    + +H    L+T+  +S  D P  +  +      DF +L+ L +  KL D           ++D  +A ++P L  K  +++E
Sbjct:  549 SKPLILFMGPWSGGKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNE--TEVLDGTQLAAD--YTFAGLQKFGQGLEERLRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYR------DFFRLNPLYEFKKLRDTCTYFRGCPITKLDLAIAYELPELAGKYKKMSE 906          
BLAST of EH domain-containing protein 1 vs. Ensembl Fly
Match: CG9297 (gene:FBgn0038181 transcript:FBtr0333192)

HSP 1 Score: 139.043 bits (349), Expect = 5.708e-34
Identity = 101/369 (27.37%), Postives = 180/369 (48.78%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFP--GIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIIS---HLKQNMPYLIRKEKKKQELISSLDEVFH---RLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQ--KLID-----------QVDNMLAVDIPILLQKIPQITE 1159
            +KP +L +G +S GK++ + YL + ++    +R G EP+   F ++M  ++  + V+ G     D    F GL KFG     R +   + + +L+ + +++ PGIL   KQ V R + +     WF  R D I L++D  KLD+  E +  +D LK  + + RIILNKAD +  ++L++V GAL+W++  ++S+ + P ++  S W  P Q     +L   +E   + DL+         KI    R A   + HA ++    +   N   L   +K+  + I    + +H    L+T+  +S  D P  +  +      DF +L+ L +  KL D           ++D  +A ++P L  K  +++E
Sbjct:  571 SKPLILFMGPWSGGKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNE--TEVLDGTQLAAD--YTFAGLQKFGQGLEERLRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYR------DFFRLNPLYEFKKLRDTCTYFRGCPITKLDLAIAYELPELAGKYKKMSE 928          
BLAST of EH domain-containing protein 1 vs. Ensembl Fly
Match: CG9297 (gene:FBgn0038181 transcript:FBtr0082828)

HSP 1 Score: 139.043 bits (349), Expect = 5.708e-34
Identity = 101/369 (27.37%), Postives = 180/369 (48.78%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFP--GIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIIS---HLKQNMPYLIRKEKKKQELISSLDEVFH---RLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQ--KLID-----------QVDNMLAVDIPILLQKIPQITE 1159
            +KP +L +G +S GK++ + YL + ++    +R G EP+   F ++M  ++  + V+ G     D    F GL KFG     R +   + + +L+ + +++ PGIL   KQ V R + +     WF  R D I L++D  KLD+  E +  +D LK  + + RIILNKAD +  ++L++V GAL+W++  ++S+ + P ++  S W  P Q     +L   +E   + DL+         KI    R A   + HA ++    +   N   L   +K+  + I    + +H    L+T+  +S  D P  +  +      DF +L+ L +  KL D           ++D  +A ++P L  K  +++E
Sbjct:  571 SKPLILFMGPWSGGKSSILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNE--TEVLDGTQLAAD--YTFAGLQKFGQGLEERLRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVGPETEAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYR------DFFRLNPLYEFKKLRDTCTYFRGCPITKLDLAIAYELPELAGKYKKMSE 928          
BLAST of EH domain-containing protein 1 vs. Ensembl Zebrafish
Match: ehd3 (EH-domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-041014-352])

HSP 1 Score: 565.074 bits (1455), Expect = 0.000e+0
Identity = 276/482 (57.26%), Postives = 359/482 (74.48%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKT+FIRYLLE+DFPG+RIGPEPTTD F+ +MH       +IPG A V D K PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  K+ KK+ELI+SL E++ R+   HQ+S GDFP +K MQEQL   D ++   LK KL+D VD+MLA DI  L+  + Q  EE     + VKGGAF       PF         +G  E  WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP++LP HL+PPSK  +
Sbjct:   57 NKPMVLLVGQYSTGKTSFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGTM--EGLIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELINSLGEIYSRIEREHQISPGDFPNLKKMQEQLQAHDLNKFQPLKMKLLDTVDDMLAHDIAQLMVLVRQ--EETQRPNQVVKGGAFEG-TMNGPFGHGYGEGAGEGIDEVEWVVARDKPMYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSDLPGHLVPPSKRKV 533          
BLAST of EH domain-containing protein 1 vs. Ensembl Zebrafish
Match: ehd1b (EH-domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-030131-2069])

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 269/479 (56.16%), Postives = 359/479 (74.95%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH +Q    +IPG A V D K PF+ LN FGN+FLNRF C+ +PN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D++ LP NAA+RK+NDLI+RARLAKV A+IIS LK+ MP +  KE KK+ELI++L E++ ++   HQ+S GDFPK+  MQE L   DF++   LK KL++ V++MLA DI  L+  + Q  EE     + V+GGAF       PF         +G  E  WVV + +  Y+EIF +L P NG ++G   +  ++K+KLP  VL ++WKL+D+D DG+LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   56 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMHGEQ--EGLIPGNALVVDPKKPFRKLNAFGNAFLNRFICAQMPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIRALKNHEDKMRVVLNKADQIGTQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWAQPLLVADNRKLFEAEEQDLFRDIQGLPRNAALRKLNDLIKRARLAKVQAYIISSLKKEMPNVFGKENKKKELIANLGEIYAKIEKEHQISPGDFPKLSKMQEVLAGQDFTKFQGLKPKLLESVEDMLANDIAKLMTLVRQ--EEASMPSQAVQGGAFEG-TMNGPFGHGYGEGAGEGIDELEWVVAKDKPTYDEIFYTLSPVNGKVSGAMAKKEMVKSKLPNNVLGKIWKLADVDKDGYLDDEEFALANHLIKVKLEGHELPADLPDHLVPPSK 529          
BLAST of EH domain-containing protein 1 vs. Ensembl Zebrafish
Match: ehd1b (EH-domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-030131-2069])

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 269/479 (56.16%), Postives = 359/479 (74.95%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH +Q    +IPG A V D K PF+ LN FGN+FLNRF C+ +PN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D++ LP NAA+RK+NDLI+RARLAKV A+IIS LK+ MP +  KE KK+ELI++L E++ ++   HQ+S GDFPK+  MQE L   DF++   LK KL++ V++MLA DI  L+  + Q  EE     + V+GGAF       PF         +G  E  WVV + +  Y+EIF +L P NG ++G   +  ++K+KLP  VL ++WKL+D+D DG+LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   56 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMHGEQ--EGLIPGNALVVDPKKPFRKLNAFGNAFLNRFICAQMPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIRALKNHEDKMRVVLNKADQIGTQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWAQPLLVADNRKLFEAEEQDLFRDIQGLPRNAALRKLNDLIKRARLAKVQAYIISSLKKEMPNVFGKENKKKELIANLGEIYAKIEKEHQISPGDFPKLSKMQEVLAGQDFTKFQGLKPKLLESVEDMLANDIAKLMTLVRQ--EEASMPSQAVQGGAFEG-TMNGPFGHGYGEGAGEGIDELEWVVAKDKPTYDEIFYTLSPVNGKVSGAMAKKEMVKSKLPNNVLGKIWKLADVDKDGYLDDEEFALANHLIKVKLEGHELPADLPDHLVPPSK 529          
BLAST of EH domain-containing protein 1 vs. Ensembl Zebrafish
Match: ehd1b (EH-domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-030131-2069])

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 269/479 (56.16%), Postives = 359/479 (74.95%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH +Q    +IPG A V D K PF+ LN FGN+FLNRF C+ +PN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D++ LP NAA+RK+NDLI+RARLAKV A+IIS LK+ MP +  KE KK+ELI++L E++ ++   HQ+S GDFPK+  MQE L   DF++   LK KL++ V++MLA DI  L+  + Q  EE     + V+GGAF       PF         +G  E  WVV + +  Y+EIF +L P NG ++G   +  ++K+KLP  VL ++WKL+D+D DG+LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   56 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMHGEQ--EGLIPGNALVVDPKKPFRKLNAFGNAFLNRFICAQMPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIRALKNHEDKMRVVLNKADQIGTQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWAQPLLVADNRKLFEAEEQDLFRDIQGLPRNAALRKLNDLIKRARLAKVQAYIISSLKKEMPNVFGKENKKKELIANLGEIYAKIEKEHQISPGDFPKLSKMQEVLAGQDFTKFQGLKPKLLESVEDMLANDIAKLMTLVRQ--EEASMPSQAVQGGAFEG-TMNGPFGHGYGEGAGEGIDELEWVVAKDKPTYDEIFYTLSPVNGKVSGAMAKKEMVKSKLPNNVLGKIWKLADVDKDGYLDDEEFALANHLIKVKLEGHELPADLPDHLVPPSK 529          
BLAST of EH domain-containing protein 1 vs. Ensembl Zebrafish
Match: ehd4 (EH-domain containing 4 [Source:ZFIN;Acc:ZDB-GENE-060810-22])

HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0
Identity = 271/478 (56.69%), Postives = 357/478 (74.69%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            +KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M++D  +  V+PG A V D K PF+ LN FGNSFLNRF CS +PN VL+SI++IDTPGILSGEKQR+ RGYD+++V+ WF +RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W +PLQ  ++R+LF+ E ++L  D++ LP NAA+RK+NDLI+RARLAKVHA+IIS+LK+ MP L  KEKKK+ELI+ L E++  L   H +S GDFP V  MQEQL   DFS+  S+K KLI+ VD ML+  I  L+  I +  EE+    + VKGGAF   + + PF       ++ G    +W+V   +  Y+EIF +L P NG +TG   +  ++ ++LP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELP ELP HL+PPS
Sbjct:  126 SKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDGFIAVMYND--NEGVVPGNALVVDPKKPFRKLNSFGNSFLNRFICSQMPNQVLQSISIIDTPGILSGEKQRISRGYDFSEVLRWFGERVDRIILLFDAHKLDISDEFSEAIRAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVVRVYLGSFWAKPLQNAENRRLFEAETQDLFRDIQGLPRNAALRKLNDLIKRARLAKVHAYIISYLKKEMPSLFGKEKKKEELIAHLPEIYQILQREHHISPGDFPNVIKMQEQLQHYDFSKFPSMKVKLIESVDRMLSTKISYLMNMIRE--EESKQPPQMVKGGAFED-SSDGPFGHGYGEGVSAGADTEDWIVSRDKHRYDEIFYTLMPVNGRVTGINAKKEMMNSRLPNTVLGKIWKLADCDKDGMLDDEEFALAQHLIKIKLEGFELPIELPNHLVPPS 598          
BLAST of EH domain-containing protein 1 vs. Ensembl Xenopus
Match: dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2 [Source:Xenbase;Acc:XB-GENE-854514])

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 273/479 (56.99%), Postives = 360/479 (75.16%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +MH D     VIPG A V D K PF+ LN FGN+FLNRF C+ LP+ VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  K+ KK+EL++ L E++ R+   HQ+S GDFP +K MQ+ L+  DF++   LK KL++ VD MLA DI  L+  + Q  EE     + VKGGAF    +  PF         +G  + +WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELPN+LP HL+PPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGD--VEGVIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPSPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPAVFGKDNKKKELVAGLGEIYARIEREHQISPGDFPNLKKMQDLLLAQDFNKFQPLKNKLLETVDEMLAHDIAHLMVLVRQ--EETQKPVQVVKGGAFEG-TQNGPFGHGYGEGAGEGIDDADWVVSRDKPMYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPNDLPCHLLPPSK 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Xenopus
Match: dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2 [Source:Xenbase;Acc:XB-GENE-854514])

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 273/482 (56.64%), Postives = 361/482 (74.90%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +MH D     VIPG A V D K PF+ LN FGN+FLNRF C+ LP+ VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  K+ KK+EL++ L E++ R+   HQ+S GDFP +K MQ+ L+  DF++   LK KL++ VD MLA DI  L+  + Q  EE     + VKGGAF    +  PF         +G  + +WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELPN+LP HL+PPSK  +
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGD--VEGVIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPSPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPAVFGKDNKKKELVAGLGEIYARIEREHQISPGDFPNLKKMQDLLLAQDFNKFQPLKNKLLETVDEMLAHDIAHLMVLVRQ--EETQKPVQVVKGGAFEG-TQNGPFGHGYGEGAGEGIDDADWVVSRDKPMYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPNDLPCHLLPPSKRKV 533          
BLAST of EH domain-containing protein 1 vs. Ensembl Xenopus
Match: ehd4 (EH domain containing 4 [Source:NCBI gene;Acc:100125054])

HSP 1 Score: 562.377 bits (1448), Expect = 0.000e+0
Identity = 274/477 (57.44%), Postives = 361/477 (75.68%), Query Frame = 2
Query:  122 PFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            P VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ ++  S  IPG A V D K PF+ LN FGN+FLNRF CS LPN+VL+SI++ID+PGILSGEKQR+ RGYD+ QV+ WFA+RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W +PLQ  ++RKLF++E ++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IISHLK+ MP +  K+ KK+ELIS L E++ +L   HQ+S GDFP VK MQ+QL   DFS+  ++K KLI+ VDNMLA  I  L+  I +  EE +   + V GGAF     E PF Q       +G  +  WVV + +  Y+E+F +L P NG ++G   +  ++ +KLP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELPN+LP HL+PPS+
Sbjct:   58 PMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGEKEGS--IPGNALVVDPKKPFRKLNSFGNAFLNRFMCSQLPNEVLRSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIRAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVVRVYIGSFWSKPLQNTENRKLFEMEAQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISHLKKEMPAVFGKDTKKKELISRLPEIYIQLQREHQISPGDFPDVKKMQQQLEMYDFSKFHTMKPKLIESVDNMLANKIAPLMSMIRE--EECNMPTQMVHGGAFEG-TMEGPFGQGYGEGAGEGAEDEEWVVAKDKPVYDELFYTLSPINGKISGVSAKKEMVNSKLPNSVLGKIWKLADNDKDGMLDDEEFALAKHLIKIKLEGYELPNDLPSHLVPPSQ 529          
BLAST of EH domain-containing protein 1 vs. Ensembl Xenopus
Match: nfe2l2 (nuclear factor, erythroid 2 like 2 [Source:Xenbase;Acc:XB-GENE-943926])

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 270/477 (56.60%), Postives = 359/477 (75.26%), Query Frame = 2
Query:  122 PFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            P VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH       V+PG A V D K PF+ L+ FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+II  LK+ MP +  KE KK+ELI++L E++ ++   HQ+S GDFP +K MQE L+  DF++  ++K KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF       PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HLIPPSK
Sbjct:   59 PMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--VEGVMPGNALVVDPKKPFRKLSAFGNAFLNRFMCAQLPNPVLESISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIIGALKKEMPNVFGKENKKKELINNLHEIYMKIEKEHQISPGDFPNIKKMQEILMTQDFAKFQAVKPKLLDTVDDMLASDIAKLMVMVRQ--EESQMTNQVVKGGAFEG-TMNGPFGHGYGEGAGEGIDDFEWVVGKDKPTYDEIFFTLSPVNGKITGASAKKEMVKSKLPNTVLGKIWKLADVDRDGLLDDEEFALANHLIKIKLEGHELPADLPSHLIPPSK 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Xenopus
Match: dyrk2 (dual specificity tyrosine phosphorylation regulated kinase 2 [Source:Xenbase;Acc:XB-GENE-854514])

HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0
Identity = 273/498 (54.82%), Postives = 361/498 (72.49%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDR----------------GYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +MH D     VIPG A V D K PF+ LN FGN+FLNRF C+ LP+ VL+SI++IDTPGILSGEKQR+ R                GYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  K+ KK+EL++ L E++ R+   HQ+S GDFP +K MQ+ L+  DF++   LK KL++ VD MLA DI  L+  + Q  EE     + VKGGAF    +  PF         +G  + +WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELPN+LP HL+PPSK  +
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGD--VEGVIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPSPVLESISVIDTPGILSGEKQRISREREESGYSGLRRCTYGGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPAVFGKDNKKKELVAGLGEIYARIEREHQISPGDFPNLKKMQDLLLAQDFNKFQPLKNKLLETVDEMLAHDIAHLMVLVRQ--EETQKPVQVVKGGAFEG-TQNGPFGHGYGEGAGEGIDDADWVVSRDKPMYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPNDLPCHLLPPSKRKV 549          
BLAST of EH domain-containing protein 1 vs. Ensembl Mouse
Match: Ehd4 (EH-domain containing 4 [Source:MGI Symbol;Acc:MGI:1919619])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 275/478 (57.53%), Postives = 360/478 (75.31%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
             KP +LL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ +   ST  PG A V D K PF+ L++FGN+FLNRF CS LPN VLKSI++ID+PGILSGEKQR+ RGYD+ QV+ WFA+RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W QPLQ  D+R+LF+ E ++L  D+++LP  AA+RK+NDLI+RARLAKVHA+IIS+LK+ MP +  KE KK+ELI  L E++ +L   +Q+S GDFP+VK+MQEQL + DF++  SLK KLI+ VDNML   I  L+  I Q  EE +   + V+GGAF+    E PF Q       +G  E  WVV + +  Y+E+F +L P NG ++G   +  ++ +KLP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELPN LP HL+PPS
Sbjct:   60 NKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGST--PGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQ--EEMNMPTQMVQGGAFDGTT-EGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPS 532          
BLAST of EH domain-containing protein 1 vs. Ensembl Mouse
Match: Ehd1 (EH-domain containing 1 [Source:MGI Symbol;Acc:MGI:1341878])

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 272/479 (56.78%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HLIPPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQAVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSK 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Mouse
Match: Ehd1 (EH-domain containing 1 [Source:MGI Symbol;Acc:MGI:1341878])

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 272/479 (56.78%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HLIPPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQAVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSK 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Mouse
Match: Ehd3 (EH-domain containing 3 [Source:MGI Symbol;Acc:MGI:1928900])

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 272/482 (56.43%), Postives = 361/482 (74.90%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M  D     +IPG A V D K PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  K+ KK+EL+++L E++ R+   HQ+S GDFP +K MQ+QL   DFS+   LK KL++ VD+MLA DI  L+  + Q  EE     + VKGGAF     + PF         +G  +  WVV   +  Y+EIF +L P +G +TG   +  ++++KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP+ELP HL+PPSK  +
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGD--VEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQ--EETQRPVQMVKGGAFEG-TLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKV 533          
BLAST of EH domain-containing protein 1 vs. Ensembl Mouse
Match: Ehd2 (EH-domain containing 2 [Source:MGI Symbol;Acc:MGI:2154274])

HSP 1 Score: 531.561 bits (1368), Expect = 0.000e+0
Identity = 257/482 (53.32%), Postives = 351/482 (72.82%), Query Frame = 2
Query:  119 KPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAIN-----EENPFQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            KP VL+ GQYSTGKT+FI+YLLE++ PG R+GPEPTTD FV +MH +  +   +PG A V D + PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSG KQRV RGYD+  V+ WFA+RVD IILLFDAHKL+ISDEF   I  L+ +++KIR++LNKADM+ +QQLM+VYGAL+W+LGKV+ TPEV RV++GS+W QPL   D+R+LF+LEE++L  D++ LP +AA+RK+NDL++RARL +VHA+IIS+LK+ MP +  KE KK++LI  L  +F ++   H +S GDFP  + MQE L+  DF++  SLK KL++ +D+MLA DI  L+  + Q  EE +  +  V+GGAF         E  P + +E      + +  WVV + +S Y+EIF +L P +G L+G + +  ++ TKLP  VL R+WKLSD+D DG LD +EFALAS+L++ KL G  LP  LP+ L+PPSK
Sbjct:   58 KPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGE--TEGTVPGNALVVDPEKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPTVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDDMLAQDIAKLMPLLRQ--EELESVEAGVQGGAFEGTRMGPFVERGPDEAIEDGEEGSEDDAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPTNLPRRLVPPSK 535          
BLAST of EH domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9EQP2|EHD4_MOUSE (EH domain-containing protein 4 OS=Mus musculus OX=10090 GN=Ehd4 PE=1 SV=1)

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 275/478 (57.53%), Postives = 360/478 (75.31%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
             KP +LL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ +   ST  PG A V D K PF+ L++FGN+FLNRF CS LPN VLKSI++ID+PGILSGEKQR+ RGYD+ QV+ WFA+RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W QPLQ  D+R+LF+ E ++L  D+++LP  AA+RK+NDLI+RARLAKVHA+IIS+LK+ MP +  KE KK+ELI  L E++ +L   +Q+S GDFP+VK+MQEQL + DF++  SLK KLI+ VDNML   I  L+  I Q  EE +   + V+GGAF+    E PF Q       +G  E  WVV + +  Y+E+F +L P NG ++G   +  ++ +KLP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELPN LP HL+PPS
Sbjct:   60 NKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGST--PGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQ--EEMNMPTQMVQGGAFDGTT-EGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPS 532          
BLAST of EH domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9H223|EHD4_HUMAN (EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1)

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 275/477 (57.65%), Postives = 361/477 (75.68%), Query Frame = 2
Query:  119 KPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            KP +LL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ +   ST  PG A V D K PF+ L++FGN+FLNRF CS LPN VLKSI++ID+PGILSGEKQR+ RGYD+ QV+ WFA+RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W QPLQ  D+R+LF+ E ++L  D+++LP  AA+RK+NDLI+RARLAKVHA+IIS+LK+ MP +  KE KK+ELIS L E++ +L   +Q+S GDFP+VK+MQEQL + DF++  SLK KLI+ VDNML+  I  L+  I Q  EE     + V+GGAF+    E PF Q       +G  E  WVV + +  Y+E+F +L P NG ++G   +  ++ +KLP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELP+ LP HL+PPS
Sbjct:   61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGST--PGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQ--EETSTPTQLVQGGAFDGTT-EGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPS 532          
BLAST of EH domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q641Z6|EHD1_RAT (EH domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Ehd1 PE=1 SV=1)

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 272/479 (56.78%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HLIPPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQAVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSK 530          
BLAST of EH domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9WVK4|EHD1_MOUSE (EH domain-containing protein 1 OS=Mus musculus OX=10090 GN=Ehd1 PE=1 SV=1)

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 272/479 (56.78%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HLIPPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQAVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLIPPSK 530          
BLAST of EH domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q5RBP4|EHD1_PONAB (EH domain-containing protein 1 OS=Pongo abelii OX=9601 GN=EHD1 PE=2 SV=1)

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 271/479 (56.58%), Postives = 361/479 (75.37%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH    +  V+PG A V D + PF+ LN FGN+FLNRF C+ LPN VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+EL+++L E++ ++   HQ+S GDFP ++ MQE L   DFS+  +LK KL+D VD+MLA DI  L+  + Q  EE+    + VKGGAF+      PF         +G  +  WVV + +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP +LP HL+PPSK
Sbjct:   57 NKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGP--TEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQ--EESLMPSQVVKGGAFDG-TMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSK 530          
BLAST of EH domain-containing protein 1 vs. TrEMBL
Match: A0A261BXB9 (Uncharacterized protein (Fragment) OS=Caenorhabditis latens OX=1503980 GN=FL83_10739 PE=3 SV=1)

HSP 1 Score: 611.683 bits (1576), Expect = 0.000e+0
Identity = 294/496 (59.27%), Postives = 376/496 (75.81%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKK-----TVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I KEKKK+ELI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+       G       TVKGGAF+   E E P  F R E   +KG  E+ W+V   +++ +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK  +     PT
Sbjct:  406 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDINRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKEKKKKELIQNLDKIYEQLQREHNISPGDFPDVNKMREKLAAQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEASAPVGANGPVDPTVKGGAFSQTTEAETPFGFGRGE-GFDKGADESEWIVNRERTSADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGMLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKRGVQDPVYPT 898          
BLAST of EH domain-containing protein 1 vs. TrEMBL
Match: A0A260YXE4 (Uncharacterized protein (Fragment) OS=Caenorhabditis remanei OX=31234 GN=FL82_18775 PE=3 SV=1)

HSP 1 Score: 611.683 bits (1576), Expect = 0.000e+0
Identity = 294/496 (59.27%), Postives = 376/496 (75.81%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKK-----TVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I KEKKK+ELI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+       G       TVKGGAF+   E E P  F R E   +KG  E+ W+V   +++ +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK  +     PT
Sbjct:  334 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDINRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKEKKKKELIQNLDKIYEQLQREHNISPGDFPDVNKMREKLAAQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEASAPVGANGPVDPTVKGGAFSQTTEAETPFGFGRGE-GFDKGADESEWIVNRERTSADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGMLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKRGVQDPVYPT 826          
BLAST of EH domain-containing protein 1 vs. TrEMBL
Match: A0A260YXU2 (Uncharacterized protein (Fragment) OS=Caenorhabditis remanei OX=31234 GN=FL82_18775 PE=3 SV=1)

HSP 1 Score: 610.912 bits (1574), Expect = 0.000e+0
Identity = 293/500 (58.60%), Postives = 375/500 (75.00%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKK-----TVKGGAFNAINE-ENPF------QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I KEKKK+ELI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+       G       TVKGGAF+   E E PF       R     +KG  E+ W+V   +++ +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P+ELPKHLIPPSK  +     PT
Sbjct:  334 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDINRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKEKKKKELIQNLDKIYEQLQREHNISPGDFPDVNKMREKLAAQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEASAPVGANGPVDPTVKGGAFSQTTEAETPFGFGRYDTRWGEGFDKGADESEWIVNRERTSADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGMLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKRGVQDPVYPT 831          
BLAST of EH domain-containing protein 1 vs. TrEMBL
Match: G0MXQ3 (Uncharacterized protein OS=Caenorhabditis brenneri OX=135651 GN=CAEBREN_20402 PE=3 SV=1)

HSP 1 Score: 610.142 bits (1572), Expect = 0.000e+0
Identity = 295/496 (59.48%), Postives = 375/496 (75.60%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKK-----TVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I KEKKK+ELI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+       G       TVKGGAF+   E E P  F R E   +KG  E  WVV   +++ +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P ELPKHLIPPSK  + +   PT
Sbjct:  300 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDINRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKEKKKKELIQNLDKIYEQLQREHNISPGDFPDVNKMREKLQAQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEASAPAGTNGSSDPTVKGGAFSQTTEAETPFGFGRGE-GFDKGADEAEWVVNRERTSADSTFESLGPVNGFLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLDADEFALANYLINLKLEGHEIPAELPKHLIPPSKRGVQEPVYPT 792          
BLAST of EH domain-containing protein 1 vs. TrEMBL
Match: A0A2P4VMD0 (Uncharacterized protein OS=Caenorhabditis remanei OX=31234 GN=FL81_20854 PE=3 SV=1)

HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0
Identity = 293/496 (59.07%), Postives = 376/496 (75.81%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKK-----TVKGGAFNAINE-ENP--FQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
             KP +LL+GQYSTGKTTFIRYLLE DFPGIRIGPEPTTDRF+ +MH D+  S  IPG A V DAK  F+ L+ FGN+FLNRFQCS LPN VL+S+T++DTPGILSGEKQR+DRGYD+T V++WFA+RVDRIILLFDAHKLDISDEFKR I+ L   ++KIRI+LNK+DM++ QQLM+VYGAL+WSLGKV  TPEV RV++GS+WD PL +D +R+LFQ E+ +L  DL+ LP NAA+RK+NDLI+RARLAKVHA+II+ L++ MP +I KEKKK+ELI +LD+++ +L   H +S GDFP V  M+E+L   DFS+ + LK KL++ VD MLA DI  L+ +IP+       G       TVKGGAF+   E E P  F R E   +KG  E+ W+V   +++ +  F SL P NG L+G+  ++H++K+KLP  VL +VWKL+D+D DG LD DEFALA+YL+ LKL G E+P++LPKHLIPPSK  +     PT
Sbjct:  416 AKPMILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDRFIAVMHGDEEGS--IPGNALVVDAKKQFRALSGFGNAFLNRFQCSTLPNQVLESVTIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFKRCIEALAGNEDKIRIVLNKSDMVDHQQLMRVYGALMWSLGKVFKTPEVSRVYLGSFWDHPLHYDINRRLFQDEQHDLFQDLQALPRNAALRKLNDLIKRARLAKVHAYIIAELRKQMPSMIGKEKKKKELIQNLDKIYEQLQREHNISPGDFPDVNKMREKLAAQDFSKFNPLKPKLLEVVDGMLATDIARLMAQIPKEEASAPVGANGPVDPTVKGGAFSQTTEAETPFGFGRGE-GFDKGADESEWIVNRERTSADSTFESLGPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGMLDADEFALANYLINLKLEGHEIPSDLPKHLIPPSKRGVQDPVYPT 908          
BLAST of EH domain-containing protein 1 vs. Ensembl Cavefish
Match: ehd1b (EH domain-containing protein 1-like [Source:NCBI gene;Acc:103046645])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 267/480 (55.62%), Postives = 364/480 (75.83%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKV 1552
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH++Q    ++PG A V D K PF+ LN FGN+FLNRF C+ +PN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK+Y++K+R++LNK+D I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D++NLP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+ELI++L E++  +   +Q+S GDFPK+  MQE L   DFS+  ++K KL++ V++ML  DI  L+  + Q  EE     +TV+GGAF    +  PF          G  E  W+V   + +Y+EIF  L P NG ++G   +  ++K+KLP  +L ++WKL+D+DGDG+LD +EFALA++L+K+KL G +LP +LP HL+PPSK+
Sbjct:   56 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMHAEQ--EGLVPGNALVVDPKKPFRKLNAFGNAFLNRFICAQMPNAVLESISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNYEDKMRVVLNKSDQIGTQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWAQPLLVADNRKLFEAEEQDLFRDIQNLPRNAALRKLNDLIKRARLAKVHAYIISALKKEMPNMFGKESKKKELIANLGEIYAMVEKEYQISPGDFPKLSKMQEILAIQDFSKFQTIKPKLMEAVEDMLTNDIARLMVLVRQ--EEAATPSQTVQGGAFEG-TKNGPFGHGYGEGAGAGIDELEWIVARDKPSYDEIFFMLSPINGKVSGAMAKKEMIKSKLPNTILGKIWKLADVDGDGYLDIEEFALANHLIKVKLEGHDLPADLPHHLVPPSKI 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Cavefish
Match: ehd1b (EH domain-containing protein 1-like [Source:NCBI gene;Acc:103046645])

HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0
Identity = 267/479 (55.74%), Postives = 363/479 (75.78%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH++Q    ++PG A V D K PF+ LN FGN+FLNRF C+ +PN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK+Y++K+R++LNK+D I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D++NLP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+ELI++L E++  +   +Q+S GDFPK+  MQE L   DFS+  ++K KL++ V++ML  DI  L+  + Q  EE     +TV+GGAF    +  PF          G  E  W+V   + +Y+EIF  L P NG ++G   +  ++K+KLP  +L ++WKL+D+DGDG+LD +EFALA++L+K+KL G +LP +LP HL+PPSK
Sbjct:   56 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMHAEQ--EGLVPGNALVVDPKKPFRKLNAFGNAFLNRFICAQMPNAVLESISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNYEDKMRVVLNKSDQIGTQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWAQPLLVADNRKLFEAEEQDLFRDIQNLPRNAALRKLNDLIKRARLAKVHAYIISALKKEMPNMFGKESKKKELIANLGEIYAMVEKEYQISPGDFPKLSKMQEILAIQDFSKFQTIKPKLMEAVEDMLTNDIARLMVLVRQ--EEAATPSQTVQGGAFEG-TKNGPFGHGYGEGAGAGIDELEWIVARDKPSYDEIFFMLSPINGKVSGAMAKKEMIKSKLPNTILGKIWKLADVDGDGYLDIEEFALANHLIKVKLEGHDLPADLPHHLVPPSK 529          
BLAST of EH domain-containing protein 1 vs. Ensembl Cavefish
Match: ehd4 (EH domain-containing protein 4 [Source:NCBI gene;Acc:103028495])

HSP 1 Score: 560.066 bits (1442), Expect = 0.000e+0
Identity = 271/478 (56.69%), Postives = 356/478 (74.48%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            +KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ +  +  V+PG A V D K PF+ LN FGN+FLNRF CS +PN VL+SI++IDTPGILSGEKQR+ RGYD+++V+ WF +RVDRIILLFDAHKLDISDEF   I   +  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W +PLQ  DSR+LF+ E ++L  D++ LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP L  KEKKK+ELI+ L E++  L   + +S GDFP V  MQEQL+  DFS+  SLK KLI+ VD ML+  I  L+  I +  EE     + V GGAF   +E+ PF       I+ G    +W+V   +  Y+EIF +L P NG +TG   +  ++ ++LP  VL ++WKL+D D DG LD +EFALA +L+K+KL G ELP+ELP HL+PP+
Sbjct:   58 SKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDGFIAVMYGE--NEGVVPGNALVVDPKKPFRKLNAFGNAFLNRFICSQMPNQVLQSISIIDTPGILSGEKQRISRGYDFSEVLRWFGERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVARVYLGSFWAKPLQNTDSRRLFEAEAQDLFRDIQALPRNAALRKLNDLIKRARLAKVHAYIISFLKKEMPSLFGKEKKKEELIARLPEIYQMLQREYHISPGDFPNVTKMQEQLMHYDFSKFPSLKIKLIEAVDKMLSNKISGLMTMIRE--EEGKQPTQVVTGGAFEG-SEDGPFGHGYGEGISAGADTEDWIVSRDKPRYDEIFYTLMPINGKVTGVNAKKEMMNSRLPNTVLGKIWKLADCDKDGMLDDEEFALAQHLIKVKLEGFELPSELPAHLVPPA 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Cavefish
Match: ehd3 (EH-domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-041014-352])

HSP 1 Score: 556.599 bits (1433), Expect = 0.000e+0
Identity = 278/500 (55.60%), Postives = 356/500 (71.20%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDR------------------GYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP +LL+GQYSTGKT+FIRYLLE+DFPG+RIGPEPTTD F+ +MH D     +IPG A V D K PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ R                  GYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA IIS LK+ MP +  KE KK+ELI+SL E++ R+   HQ+S GDFP +K MQEQL   DF +   +K KL+D  D+ML  DI  L+  + Q  EE     + VKGGAF       PF         +G  E  WVV   +  Y+EIF +L P NG + G   +  +LK+KLP  VL ++WKLSD+D DG LD +EFALA++L+K+KL G ELP+ELP HL+PPSK  I
Sbjct:   57 NKPMILLVGQYSTGKTSFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGDL--EGLIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRETAEDVCGYSCLHKCPYGGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLISDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAHIISSLKKEMPTVFGKENKKKELINSLGEIYSRIEREHQISPGDFPNLKKMQEQLQAHDFMKFQPMKMKLMDNADDMLTNDIAQLMVLVRQ--EETQRPNQVVKGGAFEG-TMNGPFGHGYGEGAGEGIDEVEWVVARDKPMYDEIFYTLSPVNGKVNGANAKKEMLKSKLPNTVLGKIWKLSDIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLVPPSKRKI 551          
BLAST of EH domain-containing protein 1 vs. Ensembl Cavefish
Match: ehd1a (EH domain-containing protein 1-like [Source:NCBI gene;Acc:103036046])

HSP 1 Score: 555.444 bits (1430), Expect = 0.000e+0
Identity = 270/480 (56.25%), Postives = 364/480 (75.83%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFN-AINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +M+ +Q    VIPG A V D K PF+ LN FGN+FLNRF C+ L N VL SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I++QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+II+ LK+ MP +  K+ KK+ELIS+L  ++ ++   H +S GDFP +K MQE L   DF++  +LK KL++ V++MLA DI  L+  + Q  EE     + VKGGAF+ A+N   PF         +G  E  WVV   + +Y+EIF +L P NG ++G   +  +LK+KLP  VL ++W L+D+D DG+LD +EFALA++L+K+KL G ELP++LP HL+PPSK
Sbjct:   55 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMYGEQ--EGVIPGNALVVDPKKPFRKLNAFGNAFLNRFMCAQLKNAVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQISTQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWAQPLLIADNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIITSLKKEMPSVFGKDSKKKELISNLGAIYEKIEKEHNISPGDFPNLKKMQELLNGQDFNKFPALKPKLLENVEDMLANDIAKLMTLVRQ--EEASMPNQIVKGGAFDGAMN--GPFGHGYGEGAGEGIDELEWVVGRDKPSYDEIFYTLSPVNGKVSGAAAKKEMLKSKLPNTVLGKIWTLADVDKDGYLDDEEFALANHLIKVKLEGYELPSKLPSHLVPPSK 528          
BLAST of EH domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ehd1a (EH-domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2518])

HSP 1 Score: 463.766 bits (1192), Expect = 4.034e-160
Identity = 225/399 (56.39%), Postives = 298/399 (74.69%), Query Frame = 2
Query:  356 RFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPFQRVEIAINKGKF-ETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            RF C+ LPN VL+SI++IDTPGILSGEKQR+ RGYD+T V+ WFA+RVDRIILLFDAHKLDISDEF   I  LK +D+KIR++LNKAD + +QQLM+VYGAL+WSLGKV++TPEV RV+MGS+W  PL   D+R+LF++EE++L  D++ LP NAA+RK+NDLI+R RLAKVHA+IISHL++ MP +  K+ KK+ELI++L E+F R+   HQ+S GDFP +K MQEQL D DF++  +LK KL ++VD ML+ DI  L+  + Q  EE     + V+GGAF    E  PF R           E +WVV + +  Y+EIF +L P +G ++G   +  ++K+KLP  VL R+WKL+D+D DG LD DEFALA++L+K+KL G ELP ELP HL+PPSK
Sbjct:    1 RFMCAQLPNPVLESISIIDTPGILSGEKQRISRGYDFTAVLTWFAERVDRIILLFDAHKLDISDEFSEVIRALKGHDDKIRVVLNKADQVETQQLMRVYGALMWSLGKVINTPEVVRVYMGSFWSNPLLIPDNRRLFEMEEQDLFKDIQTLPRNAALRKLNDLIKRTRLAKVHAYIISHLRKEMPAVFGKDAKKKELIANLGEIFTRIEREHQISAGDFPNLKKMQEQLQDQDFTKFHTLKPKLFEKVDEMLSHDIARLMGLVRQ--EEARVPSQAVRGGAFEG-TENGPFGRGYGEGAGEGADEADWVVSKDKPAYDEIFYTLSPIDGKISGASAKREMVKSKLPNTVLGRIWKLADVDKDGMLDDDEFALANHLIKVKLEGHELPEELPMHLLPPSK 396          
BLAST of EH domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007308.1 (pep scaffold:Pmarinus_7.0:GL476503:58924:70125:-1 gene:ENSPMAG00000006577.1 transcript:ENSPMAT00000007308.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 268.085 bits (684), Expect = 5.113e-82
Identity = 173/516 (33.53%), Postives = 268/516 (51.94%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLL----------EEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKS-----YDNKIRIILNKADMINSQ-QLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHR--LATVHQVSE-------GDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPI-------------LLQKIPQITEENDFGKKTVKGGAFNAINEENPFQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            + P VLL+G  + GKT+ +RYLL           +      + P   T    ++ H +   S V PG A V +A   F GL  FG++ ++R     LP  +L+S+T +DTPGI + E      G  Y  ++ W  +R DR+ L+ DA +  +S E       L+S     + +K+R++L +AD +     L++ +GAL WSLG++L     PRV+  ++ D PL++D +R L ++ E + MNDL++LP  A +R++ND+I RARLA+ HA I+S L   +P   R+        ++L E+  +  LA V +V++       GD P+++ MQE L+  D S +  ++++L+  VD +L  D P              LL    Q    +  G      G F +              +       W + E ++ Y E+F SL P  G ++G   R  LL+++LP   L RVW+LSD+D DG LD DEF +A++LV   L G ELP ELP HL+PPSK
Sbjct:   58 SPPTVLLLGAPAAGKTSLLRYLLGGPSSQQQQFLQQLQQGVLQPGSATTSVTIVQHGEAPGS-VTPGHALVLEANSAFAGLAAFGSAAMSRVVRVQLPCPILESVTFVDTPGIPNDEIATGQHGTYYGGLLAWLCERADRVALVCDAPRPSVS-ERGALATALRSLRRHLHPHKLRVLLLRADELGEPGSLLRAHGALCWSLGRLLGRVSPPRVYAAAFRDGPLRWDWNRDLLEVNERDFMNDLRSLPRLAPLRRLNDVIARARLARAHACIVSALHSQLPLFGRR--------AALTELVAQGGLAPVLEVAQQRWGLPVGDRPEMEPMQEWLMHCDMSFIRPMERRLLAAVDTLLQRDAPALLSRFRRRPRPSLLLLPGGQALPASSLGPFAEDLG-FVSATSPTCGDDDGDGDDDASSPAPWALSEEKALYEELFRSLSPVRGRVSGASARLVLLRSRLPACALRRVWRLSDVDADGMLDSDEFTVANHLVAAALRGHELPRELPPHLVPPSK 562          
BLAST of EH domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: srl (sarcalumenin [Source:ZFIN;Acc:ZDB-GENE-061110-91])

HSP 1 Score: 205.682 bits (522), Expect = 4.343e-60
Identity = 121/364 (33.24%), Postives = 191/364 (52.47%), Query Frame = 2
Query:  113 ITKPFVLLIGQYSTGKTTFIRYLLEED---FPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNM----PYLIRKEKKKQELISSLDE--VFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQK-------LIDQVDNMLAVDIPILLQKIPQIT 1156
            I KP VL +G +S GK++ I YLL  D   F     G EPTT  F VI H  +     + G    TD    F  L KFG SFL +F    +P+ +L+ +T +DTPGI+   KQ+  RGY +  V  WF  R D I ++FD  KLD+  E +     LK  +++IRIILNKAD +++QQLM+VYGAL WSL  +++  E PRV++ S+W    + D +R LF  EE  L++DL+ +  N    KI  + + A   ++HA ++    Q +     +    E+   +++   +E  ++  +     VS+ D P  K+ +        + +  L          L+D+++  ++V++P LL  +  +T
Sbjct:   50 IAKPLVLFLGPWSVGKSSMINYLLGLDDKAFSLYTGGAEPTTSEFTVIRHGTKVKH--LEGIVMATDGSRTFASLEKFGQSFLEKFSGVEMPHRLLERVTFVDTPGIIENRKQQ-QRGYPFNDVCQWFIDRGDLIFVVFDPTKLDVGLELETLFRQLKGRESQIRIILNKADSVSTQQLMRVYGALFWSLAPLINVTEPPRVYVSSFWPYAFRVDTNRGLFLAEETSLLDDLRQIIANRMENKIALIRQHAIRVRIHALVVDRYVQTLRTRSSFFSNAEQVFADIVEHPEEYNIYGSVLANSNVSKFDLPDPKTYKSFFGANSVATIRPLSYHCSYTNGCLLDKIERAISVELPALLGSLSPVT 410          
BLAST of EH domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004856.1 (pep scaffold:Pmarinus_7.0:GL476392:158221:184050:-1 gene:ENSPMAG00000004375.1 transcript:ENSPMAT00000004856.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.6709 bits (239), Expect = 3.728e-22
Identity = 48/93 (51.61%), Postives = 68/93 (73.12%), Query Frame = 2
Query: 1274 WVVE-EFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            W V+ E ++ ++ I++SL+P+NGLL+G++V+  LL +KLPV  L RVW LSD+D DGFLD DEF++A YLV   L  + +P  LP  LIPP+K
Sbjct:  121 WAVKPEEKAKFDSIYDSLKPQNGLLSGEKVKPVLLNSKLPVETLGRVWDLSDIDRDGFLDRDEFSVAMYLVYRALEKEPVPLALPIKLIPPAK 213          

HSP 2 Score: 48.9062 bits (115), Expect = 1.988e-6
Identity = 33/106 (31.13%), Postives = 56/106 (52.83%), Query Frame = 2
Query: 1196 AFNAINEENPFQRVEIAINKGKFETNWVVEEFQS----NYNEIFNSLEP-RNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLS 1498
            AF A+ E N      +A +  +F   W  +   +     Y+E+F  L+   +G +TG +V++  +KT L   VL+++W LSD    G L  D+F +A +LV+ K+ 
Sbjct:  238 AFTALFEANKL----LAKHSQRFRPLWQSQAVSAAERLKYDEMFTKLDKDGDGQVTGLEVKEVFMKTGLSPAVLAQIWALSDTRQCGKLTRDQFGMAMHLVQEKIG 339          
BLAST of EH domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1 [Source:HGNC Symbol;Acc:HGNC:24634])

HSP 1 Score: 89.3521 bits (220), Expect = 8.922e-19
Identity = 44/96 (45.83%), Postives = 68/96 (70.83%), Query Frame = 2
Query: 1265 ETNWVVE-EFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            E  WVV+ + ++ ++ IF+SL P NGLL+G++V+  L+ + LP+ VL +VW LSD+D DG LD DEFA+A +LV   L  + +P+ +P  L+PP+K
Sbjct:  119 EAFWVVKPDEKTKFDGIFDSLGPANGLLSGEKVKPVLINSNLPMEVLGKVWDLSDIDKDGHLDRDEFAVAMHLVYRALDKEPVPSVIPPKLVPPAK 214          

HSP 2 Score: 54.299 bits (129), Expect = 6.356e-8
Identity = 36/100 (36.00%), Postives = 58/100 (58.00%), Query Frame = 2
Query: 1268 TNWVVEEFQS-NYNEIFNSLE-PRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLS-GDELPNELPKHLIPPSKVNI 1558
            T WVV       Y+EIF   +   +GL++G +V+D  +++ LP  VL+++W L+D    G L  D+FAL  YL+  K+S G + P  L   ++PPS+  +
Sbjct:  282 TTWVVTPADKIKYDEIFLKTDLDMDGLVSGLEVKDIFMQSGLPQAVLAQIWALADTRQQGKLTQDQFALM-YLITQKVSKGVDPPVTLNADMMPPSERGV 380          
BLAST of EH domain-containing protein 1 vs. Ensembl Yeast
Match: PAN1 (Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease [Source:SGD;Acc:S000001445])

HSP 1 Score: 52.7582 bits (125), Expect = 1.720e-7
Identity = 33/91 (36.26%), Postives = 50/91 (54.95%), Query Frame = 2
Query: 1277 VVEEFQSNYNEIFNSLEPRN-GLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            +  E +S + +IF + + +N GLL      +   K+ L    L ++W L D++  G L+  EFAL  +LV  KL+G  +PN LP  LIP S
Sbjct:  596 ISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLIPSS 686          

HSP 2 Score: 49.2914 bits (116), Expect = 1.592e-6
Identity = 29/86 (33.72%), Postives = 47/86 (54.65%), Query Frame = 2
Query: 1271 NWVVEEFQSNYNEIFNSLEPRNG--LLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNEL 1522
            +++  + Q+ +  +F S+   NG   ++G   R  L+++ LP   L+R+W L D    G L   EFALA +L+   L GD +P EL
Sbjct:  264 SFITAQDQAKFETLFRSIV-TNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLINDVLQGDTIPYEL 348          
BLAST of EH domain-containing protein 1 vs. Ensembl Yeast
Match: EDE1 (Scaffold protein involved in the formation of early endocytic sites; putative regulator of cytokinesis; homo-oligomerization is required for localization to and organization of endocytic sites; has a network of interactions with other endocytic proteins; binds membranes in a ubiquitin-dependent manner; may also bind ubiquitinated membrane-associated proteins; interacts with Cmk2 and functions upstream of CMK2 in regulating non-apoptotic cell death; homolog of mammalian Eps15 [Source:SGD;Acc:S000000143])

HSP 1 Score: 51.2174 bits (121), Expect = 4.693e-7
Identity = 22/66 (33.33%), Postives = 36/66 (54.55%), Query Frame = 2
Query: 1301 YNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLS 1498
            ++++F+        + G + +D  LK +LP   L  +W L D D  G LD  EF +A YL++L +S
Sbjct:  139 FSQLFDRTAKGAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQLCMS 204          

HSP 2 Score: 50.0618 bits (118), Expect = 1.111e-6
Identity = 24/65 (36.92%), Postives = 41/65 (63.08%), Query Frame = 2
Query: 1292 QSNYNEIFNSLEPRN-GLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLV 1483
            Q+ YN+ F+ L+  + G++TG+ VR     + LP  +LS+VW   D+D  GFL+ +EF+ A  ++
Sbjct:   15 QAFYNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMI 79          
BLAST of EH domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO49577 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP8])

HSP 1 Score: 584.719 bits (1506), Expect = 0.000e+0
Identity = 283/482 (58.71%), Postives = 363/482 (75.31%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAF---NAINEENPFQRVEI-AINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFI+YLLE+DFPGIRIGPEPTTD F+ +MH D  S  VIPG A + D    F+ L+ FGN+FLNRF CS LPNDVL SIT++DTPGILSGEKQ V RGYD+T ++ WFA+R DRIILLFDAHKLDISDEF+R I+VL+ YD+KIRI+LNKADMIN+QQLM+VYGAL+WSLGKV++TPEV RV++GS+W+QPLQ DD+R+LF++E  +L  D++ LP NAA+RK+ND I+RARLAKVHA+IIS LK  MP +  K+KKK ELI  L +V+ ++   H +S GDFP V   +EQL   DF++  +L+ K I+ +D+MLA DIP L+  IP  T + D  K +V GGAF   +A N  NPF       +  G     WVVE+F+  Y+E+F +L P +G L+G + +  ++K+KLP   L R+WKLSD+D DG LD DEFALA YL+K+KL  +++P ELP HL+PPSK
Sbjct:   57 AKPMVLLVGQYSTGKTTFIKYLLEQDFPGIRIGPEPTTDSFIAVMHGD--SQQVIPGNALIVDPNKQFRSLSSFGNAFLNRFCCSELPNDVLNSITIVDTPGILSGEKQSVARGYDFTGILKWFAERCDRIILLFDAHKLDISDEFQRGIEVLRDYDDKIRIVLNKADMINTQQLMRVYGALMWSLGKVINTPEVARVYIGSFWNQPLQMDDNRRLFEMEATDLFRDIQELPRNAALRKLNDFIKRARLAKVHAYIISELKSQMPSMFGKDKKKDELIKKLTDVYQKIQREHNISPGDFPPVSKFKEQLKQHDFTKFHTLRAKHIETLDHMLAHDIPRLMAMIPHETTD-DASKPSVSGGAFAVHHATN--NPFASGACEGVALGAGTDTWVVEDFKPKYDELFKTLGPVDGKLSGAKAKKEMVKSKLPNTQLGRIWKLSDIDHDGCLDEDEFALAMYLIKVKLEDNDIPEELPVHLVPPSK 533          
BLAST of EH domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO43900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX50])

HSP 1 Score: 87.4261 bits (215), Expect = 8.202e-18
Identity = 37/90 (41.11%), Postives = 62/90 (68.89%), Query Frame = 2
Query: 1274 WVV-EEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIP 1540
            W++ EE ++ ++ +F S  P NG L+G+Q R   ++++LP+  LS++WKL+D+  D FLD  EFA A +L++L+L G ++P +LP  L P
Sbjct:    7 WIINEEERTRHDALFYSQNPENGFLSGEQARSLFIRSRLPLAELSKIWKLADVTRDNFLDVSEFATAMHLIQLRLKGFDIPEKLPSTLAP 96          
BLAST of EH domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO47146 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMS3])

HSP 1 Score: 68.5514 bits (166), Expect = 4.746e-12
Identity = 34/83 (40.96%), Postives = 53/83 (63.86%), Query Frame = 2
Query: 1301 YNEIFNSLE-PRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            Y ++F + +  + G L+G+QVR  L+++ LP P L+ +WKLSD+D DG L+ DEF LA + V +   G  LP  +P  L+ P+
Sbjct:  259 YTQMFKAQDFKQTGFLSGEQVRSMLIQSGLPQPSLALIWKLSDVDKDGQLNQDEFILAMHFVDMAKLGHTLPLVVPPELLTPA 341          

HSP 2 Score: 62.3882 bits (150), Expect = 3.841e-10
Identity = 32/81 (39.51%), Postives = 45/81 (55.56%), Query Frame = 2
Query: 1337 GLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
            G   G+Q +   LK+ LP  VL ++W LSD+D DG +   EF +A +L++ KL G E P+ LP  L   S  +    N PT
Sbjct:    5 GSPQGEQAKQFFLKSNLPAMVLGKIWSLSDIDRDGKMTMQEFTIAMHLIQNKLKGTEPPSVLPNTLKMTSLPSTFNRNQPT 85          
BLAST of EH domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO36122 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJH7])

HSP 1 Score: 48.1358 bits (113), Expect = 7.248e-6
Identity = 59/254 (23.23%), Postives = 111/254 (43.70%), Query Frame = 2
Query:  128 VLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGN--SFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYD----NKIRIILNKADMINSQQ-----LMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAA---IRKINDLI 847
            +L+IG +S GK++FI + +EE     R G    T  F  +    +  S  + G A +      FK L +      +L   + S         +T IDTPG++ G+   +   +D  + I W     D I + FD     +    KRT+++++  +     ++R  L+KAD    +      LM++   L    G   +  ++P +++ +  D+P +  +  +    E E+ +N      LN      +KI+D++
Sbjct:   59 LLMIGNHSAGKSSFINWYIEEHIQ--RTGVAIETQGFTFVTSGKKRES--LTGNATL-HLYSHFKPLQEIEGVVEYLTT-EISTSKQKKFPLVTFIDTPGLVDGD---MKYPFDVDEAIIWLGGLADLIFVFFDPIGQALC---KRTLNLVEHLNEDQSERLRFYLSKADTAGHESDRQKVLMQITQELCKRPGLNKAGFDMPTIYVPTMLDKPSRCANQIEDVCKEIEKTINQTIQNTLNTLEKDCQKISDIV 300          
BLAST of EH domain-containing protein 1 vs. Ensembl Medaka
Match: ehd3 (EH domain-containing protein 3 [Source:NCBI gene;Acc:101160952])

HSP 1 Score: 572.778 bits (1475), Expect = 0.000e+0
Identity = 278/482 (57.68%), Postives = 363/482 (75.31%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKT+FIRYLLE+DFPG+RIGPEPTTD F+ +MH D  +  VIPG A V D K PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+ELI+SL +++ R+   HQ+S GDFP +K MQ+ L D D ++  +LK KL++ VD+MLA DI  L+  + Q  EE+      VKGGAF+      PF         +G  E  WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP+ELP HL+PPSK  I
Sbjct:   57 NKPMVLLVGQYSTGKTSFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGD--TEGVIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISALKKEMPSVFGKENKKKELIASLGDIYKRIEREHQISPGDFPNLKKMQDLLQDQDLTRFQALKPKLLEAVDDMLASDIASLMVLVRQ--EESQRPNSAVKGGAFDG-TLNGPFGHGYGEGAGEGIDEAEWVVARDKPAYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLVPPSKRKI 533          
BLAST of EH domain-containing protein 1 vs. Ensembl Medaka
Match: ehd1a (EH domain-containing protein 1 [Source:NCBI gene;Acc:101158863])

HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0
Identity = 274/479 (57.20%), Postives = 366/479 (76.41%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VLL+GQYSTGKTTFIR+L+E+DFPG+RIGPEPTTD F+ +MH DQ    VIPG A V D K PF+ LN FGN+FLNRF C+ +PN VL+SI++IDTPGILSGEKQR+ RGYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++K+R++LNKAD I++QQLM+VYGAL+WSLGK+++TPEV RV++GS+W QPL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+II+ LK+ MP +  KE KK+ELI++L E++HR+   H +S GDFPK++ MQE L   DF++ ++LK KL++ V++MLA DI  L+  + Q  EE +   ++VKGGAF       PF        ++G  E  WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP  LP HL+PPSK
Sbjct:   52 NKPMVLLVGQYSTGKTTFIRHLMEQDFPGMRIGPEPTTDSFIAVMHGDQ--EGVIPGNALVVDPKKPFRKLNAFGNAFLNRFMCAQMPNAVLESISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIRALKNHEDKMRVVLNKADQISTQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWAQPLLVPDNRKLFEAEEQDLFVDIQSLPRNAALRKLNDLIKRARLAKVHAYIITALKKEMPAVFGKESKKKELITNLGEIYHRVEKEHNISPGDFPKLEKMQELLNGHDFTKFANLKPKLLEAVEDMLANDIARLMALVRQ--EEANMPSQSVKGGAFEG-TMSGPFGHGYGEGASEGIDELEWVVGRDKPTYDEIFYTLSPINGKVTGAAAKKEMVKSKLPNSVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPASLPDHLVPPSK 525          
BLAST of EH domain-containing protein 1 vs. Ensembl Medaka
Match: ehd3 (EH domain-containing protein 3 [Source:NCBI gene;Acc:101160952])

HSP 1 Score: 562.377 bits (1448), Expect = 0.000e+0
Identity = 278/498 (55.82%), Postives = 363/498 (72.89%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDR----------------GYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNI 1558
             KP VLL+GQYSTGKT+FIRYLLE+DFPG+RIGPEPTTD F+ +MH D  +  VIPG A V D K PF+ LN FGN+FLNRF C+ LPN VL+SI++IDTPGILSGEKQR+ R                GYD+  V++WFA+RVDRIILLFDAHKLDISDEF   I  LK++++KIR++LNKAD I +QQLM+VYGAL+WSLGK+++TPEV RV++GS+W  PL   D+RKLF+ EE++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS LK+ MP +  KE KK+ELI+SL +++ R+   HQ+S GDFP +K MQ+ L D D ++  +LK KL++ VD+MLA DI  L+  + Q  EE+      VKGGAF+      PF         +G  E  WVV   +  Y+EIF +L P NG +TG   +  ++K+KLP  VL ++WKL+D+D DG LD +EFALA++L+K+KL G ELP+ELP HL+PPSK  I
Sbjct:   57 NKPMVLLVGQYSTGKTSFIRYLLEQDFPGMRIGPEPTTDSFIAVMHGD--TEGVIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRDKEMSGYSCLHRCPYGGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISALKKEMPSVFGKENKKKELIASLGDIYKRIEREHQISPGDFPNLKKMQDLLQDQDLTRFQALKPKLLEAVDDMLASDIASLMVLVRQ--EESQRPNSAVKGGAFDG-TLNGPFGHGYGEGAGEGIDEAEWVVARDKPAYDEIFYTLSPVNGKVTGANAKREMVKSKLPNTVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLVPPSKRKI 549          
BLAST of EH domain-containing protein 1 vs. Ensembl Medaka
Match: ehd4 (EH domain-containing protein 4 [Source:NCBI gene;Acc:101167502])

HSP 1 Score: 561.607 bits (1446), Expect = 0.000e+0
Identity = 271/478 (56.69%), Postives = 357/478 (74.69%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPF-QRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS 1546
            +KP VLL+GQYSTGKTTFIRYLLE+DFPG+RIGPEPTTD F+ +M+ +  +  V+PG A V D+K PF+ LN FGN+FLNRF CS +PN VL+SI++IDTPGILSGEKQR+ RGYD+ +V+ WF +RVDRIILLFDAHKLDISDEF   I  LK  D+KIR++LNKAD +++QQLM+VYGAL+WSLGKV++TPEV RV++GS+W +PLQ  ++R+LF+ E ++L  D+++LP NAA+RK+NDLI+RARLAKVHA+IIS+LK+ MP L  +EKKK+ELI  L E++  L   H +S GDFP V  MQ+ L   DF +  SLK KLI+ VD MLA  I +L+  I +  EE+      V GGAF   +++ PF Q     I+ G    +W+V   +  Y+EIF +L P NG +TG   +  ++ ++LP  VL ++WKL+D D DG LD DEFALA +L+K+KL G ELP+ELP HL+PPS
Sbjct:   58 SKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDGFIAVMYGE--NEGVVPGNALVVDSKKPFRKLNAFGNAFLNRFICSQMPNQVLQSISIIDTPGILSGEKQRISRGYDFAEVLRWFGERVDRIILLFDAHKLDISDEFSEAIRALKGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVVRVYLGSFWAKPLQNTENRRLFEAESQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISYLKKEMPTLFGREKKKEELIMRLPEIYTILQREHHISAGDFPNVNKMQDMLQHYDFHKFPSLKMKLIESVDKMLATKIAVLMAMIRE--EESKQPAPFVSGGAFEG-SQDGPFGQGYGEGISAGADAEDWIVSRDKHRYDEIFYTLMPVNGKITGVNAKKEMMNSRLPNTVLGKIWKLADCDQDGMLDDDEFALAQHLIKIKLEGYELPSELPDHLVPPS 530          
BLAST of EH domain-containing protein 1 vs. Ensembl Medaka
Match: EHD2 (EH domain containing 2 [Source:NCBI gene;Acc:101167558])

HSP 1 Score: 533.102 bits (1372), Expect = 0.000e+0
Identity = 264/484 (54.55%), Postives = 350/484 (72.31%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFG-KKTVKGGAF-----NAINEENPFQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
             KP VL++GQYSTGKTTFI+YLLE+D PG R+GPEPTTD F  IMH +     VIPG A + D   PF+ LN FGN+FLNRFQC+ +PN VL+SI++IDTPGILSG KQRV RGYD+  V+ WFA+RVDRI+LLFDAHKL+ISDEF   I  LK  ++K+R++LNKADM+ +QQLM+VYGAL+WSLGKV  TPEV RV++GS+W +PL   D+RKLF+LEEE+L  +++NLP NAA+RK+NDL++RARL +VHA IIS+LKQ MP + RK+ KK+ LI  L  +F ++   H +S GDFP    MQEQL+  DF++  +LK  L+  +D +L+ DI  L+  + Q  EE + G +  V+GGAF        NE +PF   E      + E +WVV + +  Y+EIF +L P  G L+G + +D ++ ++LP  VL R+WKLSD+D DG LD +EFALAS+L+++KL G  LP ELP  L+PPSK
Sbjct:   55 NKPMVLVVGQYSTGKTTFIKYLLEQDIPGSRVGPEPTTDCFTAIMHGE--VEGVIPGNALIVDPNKPFRKLNPFGNTFLNRFQCAQMPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDRIVLLFDAHKLEISDEFSEAIGALKGNEDKLRVVLNKADMVGTQQLMRVYGALMWSLGKVFGTPEVLRVYIGSFWSEPLMVSDNRKLFELEEEDLFAEIQNLPRNAALRKLNDLVKRARLVRVHAHIISYLKQEMPSVFRKDNKKKNLIYQLPVIFSKIQLQHNISPGDFPDCAKMQEQLMVHDFTKFKTLKPNLMAALDELLSSDIAKLMPLLRQ--EELEAGDQPGVQGGAFMGTRAGPFNEGDPF--AEENGEGCEEEGDWVVTKDKPKYDEIFYNLAPNEGKLSGPKAKDWMVSSRLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEVKLEGHGLPPELPSRLVPPSK 532          
BLAST of EH domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000006379.1 (SMESG000006379.1)

HSP 1 Score: 992.26 bits (2564), Expect = 0.000e+0
Identity = 486/488 (99.59%), Postives = 486/488 (99.59%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPFQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 1579
             KP VLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPFQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT
Sbjct:   50 AKPLVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFGKKTVKGGAFNAINEENPFQRVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT 537          

HSP 2 Score: 69.3218 bits (168), Expect = 4.525e-12
Identity = 33/33 (100.00%), Postives = 33/33 (100.00%), Query Frame = 1
Query:   16 MSKKIVENPTTFGVLADLYKLYTRKLLPLEKTY 114
            MSKKIVENPTTFGVLADLYKLYTRKLLPLEKTY
Sbjct:    1 MSKKIVENPTTFGVLADLYKLYTRKLLPLEKTY 33          
BLAST of EH domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000026849.1 (SMESG000026849.1)

HSP 1 Score: 612.453 bits (1578), Expect = 0.000e+0
Identity = 298/484 (61.57%), Postives = 378/484 (78.10%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIP-QITEENDFGKKTVKGGAFNAINEENPFQ-RVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNIL 1561
             KP VLL+GQYSTGKTTFIRYLLE+DFPGIRIGPEPTTD+F+ IM  ++  +  IPG A V D K PF+ L+KFGN+FL RFQCSM+ N VL+SI +IDTPGILSGEKQR+DRGY +++VI+WFA+RVDRIILLFDAHKLDISDEF+R I++LK Y+ KIRI+LNK DM++SQQLM+VYGAL+WSLGKVL TPEV RV++GS+WDQPL FD +RKLF+LEE++L  DL++LP N+ +RK+ND IRRARLAKVHA+IIS L+  MP LI K+ KK+ELI +L  ++ R++  H +S GDFPK++ MQ  L D DF    +LKQKLI+ VD+MLA DI  L+Q IP + T +N+F    VKGGAF  +  +NPF       IN+GKF+T W V +F++ Y+E F SL P NG + G   +D+L+KTKLP  +L ++WKLSD+D DG LD DEFALA YLV+LKL  +E+P  LP HLIPP+K  I+
Sbjct:   54 AKPMVLLLGQYSTGKTTFIRYLLEQDFPGIRIGPEPTTDKFIAIMFDEKEGT--IPGNALVVDPKRPFRPLSKFGNNFLTRFQCSMIKNPVLESINIIDTPGILSGEKQRLDRGYSFSEVIEWFAERVDRIILLFDAHKLDISDEFRRVIELLKGYEEKIRIVLNKCDMVDSQQLMRVYGALMWSLGKVLYTPEVARVYIGSFWDQPLHFDTNRKLFELEEKDLFEDLRSLPRNSTVRKLNDFIRRARLAKVHAYIISALRDEMPALIGKDNKKKELIQNLQGIYDRISRQHSISPGDFPKIERMQNLLPDHDFKAFPTLKQKLIETVDDMLANDIAKLMQMIPKEQTAQNEF-TNPVKGGAFE-VQHDNPFGIGASEGINRGKFDTEWAVAKFKNEYDETFRSLHPVNGKINGTTAKDYLVKTKLPYNILGKIWKLSDIDLDGALDQDEFALAMYLVRLKLDNEEIPGTLPDHLIPPTKREIV 533          
BLAST of EH domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000001303.1 (SMESG000001303.1)

HSP 1 Score: 595.119 bits (1533), Expect = 0.000e+0
Identity = 303/486 (62.35%), Postives = 383/486 (78.81%), Query Frame = 2
Query:  116 TKPFVLLIGQYSTGKTTFIRYLLEEDFPGIRIGPEPTTDRFVVIMHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKSITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISDEFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPEVPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLIRRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQVSEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIPQITEENDFG---KKTVKGGAFNAINEENPFQ-RVEIAINKGKFETNWVVEEFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNIL 1561
             KP V+L+GQYSTGKTTFIRY+LEEDFPG+RIGPEPTTD FV +M  D+  S +IPG A V D K  F+ L+KFGN+FLNRFQC  L N VLK+IT IDTPGILSGEKQR+DRGY++ QVI+WFA+RVDRIILLFDAHKLDISDEFKR I++LK Y++KIRI+LNKAD I+SQQLM+VYGAL+WSLGKVL TPEV RV++GS+WDQPL +D +RKLF+LEE +LM+DL++LP NAA+RK+NDLI+RARLAKVHA+IIS LK  MP L+ KE KK+ELIS+L   + +++  + +S GDFPK+  MQE L D DF   S LK KLI+ VDNMLA D+  L+Q IP+  E++D     +  VKGGAF+ + ++N F       INKGKF+ +WVV   +  Y+EIF SL P NG + G   +++++KTKLP  +L ++WKLSD+D DGFLD DEFALASYL++LKL G+E+P+ LP HL+PPSK  I+
Sbjct:   54 AKPMVMLLGQYSTGKTTFIRYILEEDFPGMRIGPEPTTDSFVSLMDGDK--SGMIPGNALVVDTKRQFRPLSKFGNNFLNRFQCVTLNNPVLKTITFIDTPGILSGEKQRLDRGYNFGQVIEWFAERVDRIILLFDAHKLDISDEFKRVIELLKGYEDKIRIVLNKADRIDSQQLMRVYGALMWSLGKVLYTPEVTRVYIGSFWDQPLHYDTNRKLFELEEHDLMSDLQSLPANAALRKLNDLIKRARLAKVHAYIISSLKNQMPSLLGKESKKKELISNLQRTYDQISKEYSISIGDFPKIDRMQEILQDCDFKTFSPLKMKLIEDVDNMLANDVAKLMQMIPK--EQSDSTGQFEHRVKGGAFD-VQQDNLFGIGASDGINKGKFDDDWVVGRKRYEYDEIFKSLNPANGKINGTVAKEYMIKTKLPYNILGKIWKLSDVDLDGFLDIDEFALASYLLELKLEGEEIPSTLPDHLVPPSKRAIV 534          
BLAST of EH domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000037239.1 (SMESG000037239.1)

HSP 1 Score: 85.5001 bits (210), Expect = 4.410e-17
Identity = 43/105 (40.95%), Postives = 65/105 (61.90%), Query Frame = 2
Query: 1241 IAINKGKFETN-WVVE-EFQSNYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSK 1549
            +A+N     TN W +  + Q+ Y+++F SL P N  L+G  V+   L +KL VP L ++W L+D+D DG+LD +EF LA + +   L+ +ELP  LP + IP SK
Sbjct:  110 LAVNSAMSPTNIWAISNDEQARYSKVFESLNPVNNKLSGDAVKPVFLNSKLSVPTLGQIWTLADIDADGYLDREEFCLAMHFIYKCLANEELPKTLPINFIPLSK 214          

HSP 2 Score: 60.8474 bits (146), Expect = 2.673e-9
Identity = 29/102 (28.43%), Postives = 62/102 (60.78%), Query Frame = 2
Query: 1256 GKFETNWVVEEFQ-SNYNEIFNSLEP-RNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLS---GDELPNELPKHLIPPS 1546
            G   ++WV+ + +   Y+ +F + +  ++G ++G +++D  +++ LP   L+++W L D++  G L+ ++FALA YL+  ++S      +P+ L   +IPPS
Sbjct:  247 GSSSSDWVIGKLEKERYDNLFFAADKDKDGFVSGLEIKDTFVQSGLPQTELAKIWDLCDINKTGLLNSEQFALAMYLINQQISSAGSKPIPSSLALDMIPPS 348          
BLAST of EH domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000066021.1 (SMESG000066021.1)

HSP 1 Score: 81.6481 bits (200), Expect = 1.058e-15
Identity = 47/122 (38.52%), Postives = 68/122 (55.74%), Query Frame = 2
Query: 1313 FNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT*SIFRSLPSSMKFYQQLP*ITISTTNCATNFVP 1678
            F  L P NG +TG Q +    K+ LP  VL R+W L+D D DG ++ +EFA+A +L+K KL G ELP+ LP  L P      L+ N+ T S    +P S   Y  +P +  +T++  +N  P
Sbjct:   22 FQCLNPVNGFITGNQAKSLFTKSNLPTDVLGRIWFLADYDKDGCMNSNEFAIAMHLIKRKLEGYELPDVLPLSLNP------LQTNATTMSYSGYMPVS-NTYNTMP-VMHNTSHAMSNNNP 135          

HSP 2 Score: 79.7221 bits (195), Expect = 3.821e-15
Identity = 50/124 (40.32%), Postives = 72/124 (58.06%), Query Frame = 2
Query: 1220 NPFQRVEIAINKGKFET-----NWVV-EEFQSNYNEIFNSLEPRN--GLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFLDCDEFALASYLVKLKLSGDELPNELPKHLIPPS--KVNIL 1561
            NP   V   INK    T     +WV+ +  +  Y   FN  + RN  G LTG + +  L+++ LP   L+ +W L+D+D DG L C+EF +A +LV+   SG +LPN+LP+ L+PPS  K NIL
Sbjct:  181 NPSYAVPQDINKPPIHTVTSDDDWVIPQSVRPRYRLQFNQ-QDRNKRGFLTGVEAKAILVQSGLPNTSLASIWSLADIDQDGNLTCEEFCIAMHLVEQARSGRQLPNQLPQSLLPPSLQKKNIL 303          
The following BLAST results are available for this feature:
BLAST of EH domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
EHD40.000e+057.65EH domain containing 4 [Source:HGNC Symbol;Acc:HGN... [more]
EHD10.000e+056.58EH domain containing 1 [Source:HGNC Symbol;Acc:HGN... [more]
EHD10.000e+056.58EH domain containing 1 [Source:HGNC Symbol;Acc:HGN... [more]
EHD10.000e+056.58EH domain containing 1 [Source:HGNC Symbol;Acc:HGN... [more]
EHD30.000e+056.85EH domain containing 3 [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rme-10.000e+059.67Receptor Mediated Endocytosis [Source:UniProtKB/T... [more]
rme-10.000e+059.67Receptor Mediated Endocytosis [Source:UniProtKB/T... [more]
rme-10.000e+058.98Receptor Mediated Endocytosis [Source:UniProtKB/T... [more]
rme-10.000e+058.98Receptor Mediated Endocytosis [Source:UniProtKB/T... [more]
rme-10.000e+059.67Receptor Mediated Endocytosis [Source:UniProtKB/T... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Past10.000e+059.25gene:FBgn0016693 transcript:FBtr0082654[more]
Past10.000e+059.25gene:FBgn0016693 transcript:FBtr0082655[more]
CG92973.956e-3427.37gene:FBgn0038181 transcript:FBtr0082827[more]
CG92975.708e-3427.37gene:FBgn0038181 transcript:FBtr0333192[more]
CG92975.708e-3427.37gene:FBgn0038181 transcript:FBtr0082828[more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ehd30.000e+057.26EH-domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ehd1b0.000e+056.16EH-domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-... [more]
ehd1b0.000e+056.16EH-domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-... [more]
ehd1b0.000e+056.16EH-domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-... [more]
ehd40.000e+056.69EH-domain containing 4 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dyrk20.000e+056.99dual specificity tyrosine phosphorylation regulate... [more]
dyrk20.000e+056.64dual specificity tyrosine phosphorylation regulate... [more]
ehd40.000e+057.44EH domain containing 4 [Source:NCBI gene;Acc:10012... [more]
nfe2l20.000e+056.60nuclear factor, erythroid 2 like 2 [Source:Xenbase... [more]
dyrk20.000e+054.82dual specificity tyrosine phosphorylation regulate... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ehd40.000e+057.53EH-domain containing 4 [Source:MGI Symbol;Acc:MGI:... [more]
Ehd10.000e+056.78EH-domain containing 1 [Source:MGI Symbol;Acc:MGI:... [more]
Ehd10.000e+056.78EH-domain containing 1 [Source:MGI Symbol;Acc:MGI:... [more]
Ehd30.000e+056.43EH-domain containing 3 [Source:MGI Symbol;Acc:MGI:... [more]
Ehd20.000e+053.32EH-domain containing 2 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of EH domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9EQP2|EHD4_MOUSE0.000e+057.53EH domain-containing protein 4 OS=Mus musculus OX=... [more]
sp|Q9H223|EHD4_HUMAN0.000e+057.65EH domain-containing protein 4 OS=Homo sapiens OX=... [more]
sp|Q641Z6|EHD1_RAT0.000e+056.78EH domain-containing protein 1 OS=Rattus norvegicu... [more]
sp|Q9WVK4|EHD1_MOUSE0.000e+056.78EH domain-containing protein 1 OS=Mus musculus OX=... [more]
sp|Q5RBP4|EHD1_PONAB0.000e+056.58EH domain-containing protein 1 OS=Pongo abelii OX=... [more]
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BLAST of EH domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A261BXB90.000e+059.27Uncharacterized protein (Fragment) OS=Caenorhabdit... [more]
A0A260YXE40.000e+059.27Uncharacterized protein (Fragment) OS=Caenorhabdit... [more]
A0A260YXU20.000e+058.60Uncharacterized protein (Fragment) OS=Caenorhabdit... [more]
G0MXQ30.000e+059.48Uncharacterized protein OS=Caenorhabditis brenneri... [more]
A0A2P4VMD00.000e+059.07Uncharacterized protein OS=Caenorhabditis remanei ... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ehd1b0.000e+055.63EH domain-containing protein 1-like [Source:NCBI g... [more]
ehd1b0.000e+055.74EH domain-containing protein 1-like [Source:NCBI g... [more]
ehd40.000e+056.69EH domain-containing protein 4 [Source:NCBI gene;A... [more]
ehd30.000e+055.60EH-domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ehd1a0.000e+056.25EH domain-containing protein 1-like [Source:NCBI g... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ehd1a4.034e-16056.39EH-domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-... [more]
ENSPMAT00000007308.15.113e-8233.53pep scaffold:Pmarinus_7.0:GL476503:58924:70125:-1 ... [more]
srl4.343e-6033.24sarcalumenin [Source:ZFIN;Acc:ZDB-GENE-061110-91][more]
ENSPMAT00000004856.13.728e-2251.61pep scaffold:Pmarinus_7.0:GL476392:158221:184050:-... [more]
EPS15L18.922e-1945.83epidermal growth factor receptor pathway substrate... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
PAN11.720e-736.26Part of actin cytoskeleton-regulatory complex Pan1... [more]
EDE14.693e-733.33Scaffold protein involved in the formation of earl... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO495770.000e+058.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO439008.202e-1841.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO471464.746e-1240.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361227.248e-623.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of EH domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ehd30.000e+057.68EH domain-containing protein 3 [Source:NCBI gene;A... [more]
ehd1a0.000e+057.20EH domain-containing protein 1 [Source:NCBI gene;A... [more]
ehd30.000e+055.82EH domain-containing protein 3 [Source:NCBI gene;A... [more]
ehd40.000e+056.69EH domain-containing protein 4 [Source:NCBI gene;A... [more]
EHD20.000e+054.55EH domain containing 2 [Source:NCBI gene;Acc:10116... [more]
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BLAST of EH domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000006379.14.525e-1299.59SMESG000006379.1[more]
SMESG000026849.10.000e+061.57SMESG000026849.1[more]
SMESG000001303.10.000e+062.35SMESG000001303.1[more]
SMESG000037239.14.410e-1740.95SMESG000037239.1[more]
SMESG000066021.11.058e-1538.52SMESG000066021.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011830 ID=SMED30011830|Name=EH domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1879bp
CTTATATGTTTTAGAATGTCTAAAAAAATTGTTGAAAATCCTACAACTTT
TGGAGTTTTAGCAGATCTTTATAAGTTATATACAAGAAAACTTTTACCTT
TAGAGAAAACATATAACAAAACCATTCGTGTTACTAATTGGTCAATACTC
TACAGGTAAAACCACTTTTATTAGATATTTACTCGAAGAAGATTTCCCGG
GTATTAGAATTGGTCCAGAACCAACAACAGATCGTTTTGTAGTTATAATG
CATAGTGATCAAGGCAGCAGTACCGTAATTCCCGGCCAAGCGGCGGTTAC
TGATGCTAAATTGCCGTTTAAAGGATTAAATAAATTTGGAAATTCGTTTC
TTAATAGATTTCAATGTTCCATGTTACCAAATGATGTTTTGAAAAGTATA
ACATTAATAGATACCCCAGGGATTTTGAGTGGTGAAAAACAGAGAGTTGA
CCGAGGTTATGATTACACTCAAGTAATTGATTGGTTTGCCCAACGAGTTG
ATCGCATCATTCTACTATTTGATGCTCATAAGTTGGATATTTCCGACGAA
TTCAAACGTACCATCGATGTTTTAAAAAGTTATGATAATAAAATTCGAAT
AATTCTTAACAAAGCCGATATGATAAATTCTCAGCAATTGATGAAAGTAT
ATGGTGCCCTATTGTGGAGTCTTGGAAAGGTATTAAGTACACCGGAAGTT
CCTCGAGTTTTCATGGGCTCATATTGGGACCAACCATTGCAATTTGATGA
CAGTCGAAAACTGTTTCAATTAGAAGAAGAAGAACTAATGAATGATTTGA
AAAATTTGCCATTGAATGCAGCAATCAGAAAAATTAATGATTTAATTAGA
CGCGCAAGATTGGCCAAGGTTCATGCATTCATAATAAGTCATTTAAAACA
AAATATGCCTTATTTAATAAGAAAAGAAAAGAAAAAACAAGAATTAATAA
GCAGTTTAGATGAAGTGTTCCATAGATTGGCAACTGTCCATCAAGTATCC
GAAGGAGATTTTCCAAAAGTAAAAAGTATGCAAGAACAATTAATTGATAC
TGATTTCTCACAACTATCATCACTTAAACAAAAATTGATTGATCAAGTCG
ACAATATGCTTGCGGTTGACATTCCAATTCTTTTACAGAAAATACCACAA
ATAACTGAAGAAAATGATTTCGGTAAAAAAACTGTGAAAGGCGGCGCATT
TAATGCGATTAATGAAGAAAATCCATTCCAGCGGGTGGAAATCGCCATCA
ACAAAGGCAAATTCGAAACGAATTGGGTCGTTGAAGAATTTCAATCGAAT
TATAATGAAATTTTTAATTCCCTTGAACCAAGAAATGGGCTGCTTACAGG
CCAACAGGTCAGAGATCATCTTTTGAAGACGAAATTACCGGTGCCAGTGT
TGAGTCGAGTTTGGAAATTATCGGATTTGGATGGCGACGGATTCTTGGAC
TGCGACGAATTTGCTTTGGCGTCTTACTTGGTGAAATTGAAACTGAGTGG
GGACGAGTTGCCAAATGAACTGCCAAAGCATTTAATCCCCCCGTCAAAAG
TCAACATTCTAAAAATCAACAGCCCGACATGATCTATATTTAGATCTTTG
CCTTCATCAATGAAATTTTATCAACAATTACCGTGAATTACGATTTCCAC
AACTAACTGTGCTACAAATTTTGTGCCTGAATTGAAAATTGTCCGGATTT
TGGTTTGTGCGCATTAAATGCATAATAATAGATTTGTTTGGTTTATTATT
ACAGAATGTGTGTATGTGTGTGCGTGCGACTGCGTGTATACGCGCGGTAC
TTTTTAATGGCCAATATTGATTTGTTTTATTGTATTTTGATTATTCCGTG
CTTTTATTGATTAAAATAATTACATATCT
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protein sequence of SMED30011830-orf-1

>SMED30011830-orf-1 ID=SMED30011830-orf-1|Name=SMED30011830-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=445bp
MHSDQGSSTVIPGQAAVTDAKLPFKGLNKFGNSFLNRFQCSMLPNDVLKS
ITLIDTPGILSGEKQRVDRGYDYTQVIDWFAQRVDRIILLFDAHKLDISD
EFKRTIDVLKSYDNKIRIILNKADMINSQQLMKVYGALLWSLGKVLSTPE
VPRVFMGSYWDQPLQFDDSRKLFQLEEEELMNDLKNLPLNAAIRKINDLI
RRARLAKVHAFIISHLKQNMPYLIRKEKKKQELISSLDEVFHRLATVHQV
SEGDFPKVKSMQEQLIDTDFSQLSSLKQKLIDQVDNMLAVDIPILLQKIP
QITEENDFGKKTVKGGAFNAINEENPFQRVEIAINKGKFETNWVVEEFQS
NYNEIFNSLEPRNGLLTGQQVRDHLLKTKLPVPVLSRVWKLSDLDGDGFL
DCDEFALASYLVKLKLSGDELPNELPKHLIPPSKVNILKINSPT*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0032456endocytic recycling
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR040990DUF5600
IPR029952EHD4
IPR000261EH_dom
IPR027417P-loop_NTPase
IPR011992EF-hand-dom_pair
IPR022812Dynamin_SF
IPR018247EF_Hand_1_Ca_BS
IPR002048EF_hand_dom
IPR030381G_DYNAMIN_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005509calcium ion binding
GO:0005525GTP binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000261EH domainSMARTSM00027eh_3coord: 342..435
e-value: 6.2E-37
score: 138.7
IPR000261EH domainPFAMPF12763EF-hand_4coord: 350..441
e-value: 6.6E-18
score: 64.6
IPR000261EH domainPROSITEPS50031EHcoord: 348..436
score: 20.929
IPR000261EH domainCDDcd00052EHcoord: 352..417
e-value: 3.02061E-20
score: 82.2674
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1..198
e-value: 2.5E-59
score: 202.7
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 335..436
e-value: 1.9E-29
score: 103.4
NoneNo IPR availablePANTHERPTHR11216EH DOMAINcoord: 8..436
NoneNo IPR availableCDDcd09913EHDcoord: 1..202
e-value: 9.9202E-110
score: 321.53
IPR040990Domain of unknown function DUF5600PFAMPF18150DUF5600coord: 190..296
e-value: 1.8E-38
score: 131.4
IPR029952EH domain-containing protein 4PANTHERPTHR11216:SF57EH DOMAIN-CONTAINING PROTEIN 4coord: 8..436
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 393..405
IPR030381Dynamin-type guanine nucleotide-binding (G) domainPROSITEPS51718G_DYNAMIN_2coord: 1..188
score: 20.538
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 380..415
score: 9.464
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 346..433
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 27..226