slc22a-7
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30011820 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of slc22a-7 vs. Ensembl Human
Match: SLC22A4 (solute carrier family 22 member 4 [Source:HGNC Symbol;Acc:HGNC:10968]) HSP 1 Score: 91.2781 bits (225), Expect = 9.947e-19 Identity = 106/446 (23.77%), Postives = 207/446 (46.41%), Query Frame = 3
Query: 186 NFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNV-----AGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNK---WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKW-QSIFRMIFGSIGKVLVITSSQGVL-VYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI 1484
NF+ E + + + + ++G W FS + + T++++++LVC+ + L L++ L+ V G L+D++GRK + ++++T +F+ F+ + + +G + S Y + ++ E++ K R + +FF +V + PL Y R+WR+ L P +L V L F+PESPRWL + + ++ + +Q A +N + + + E + K + F+ N + SL S+ A+ +D L + Y++ F+ L+E P + ++L + R+ +I +G + L + L VD + SI ++ G G ITS+ +L V+ EL+PT R++ G+ + A Y L + +P ++ L ++ L +F PE+ G+ +PET+
Sbjct: 91 NFSALGLEPGRDVDLGQLEQESCLDG-------WEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFF----AVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGG-GVLLFIQLVPVDYYFLSIGLVMLGKFG----ITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILT-LFFPESLGMTLPETL 519
BLAST of slc22a-7 vs. Ensembl Human
Match: SLC22A13 (solute carrier family 22 member 13 [Source:HGNC Symbol;Acc:HGNC:8494]) HSP 1 Score: 88.5817 bits (218), Expect = 6.707e-18 Identity = 116/495 (23.43%), Postives = 205/495 (41.41%), Query Frame = 3
Query: 84 KKDTFKVIAF--LILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPV-FGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDL------QLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRK----RMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQE 1523
K TF + A L+LS+P G L+ N + Q + SH+ ++ C M W + ++ ++++LVCD K++ D ++ + L+ + FG L D+ GRK + L + T+ AF P+ ++ R + + + V L+ E V +R A S+ V Y RNWRL Q+ P +L + +PES RWL + + + ++ +Q A++N+ L QL P EKT N + F+ + F S+ + + + ++Y++ + G +E P S M F RK + + + I IF+ L V ++ +GK+ + VY+ ELFPT R G++ I + + L +++ +PMLIY L +++ L+ +PET G + +T+ D L R +
Sbjct: 56 KNHTFNLSAAEQLVLSVPLDTAGHPEPCLMFRPPPANASLQ-DILSHRFNETQP-CDMG----------WEYPENRL-PSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPELMNQLVP-----EKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPADLPVVVTMLAV-------VGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVA-GLLCTLLPETHGQGLKDTLQDLELGPHPRSPK 524
BLAST of slc22a-7 vs. Ensembl Human
Match: SLC22A3 (solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967]) HSP 1 Score: 87.8113 bits (216), Expect = 1.098e-17 Identity = 58/180 (32.22%), Postives = 94/180 (52.22%), Query Frame = 3
Query: 312 KTIMSDYDLVCDYKYVGDL---LVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIG-FSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFV-PESPRWLCVKNKKQQLMESLQTIANIN 836
TI+S++DLVC ++ DL ++ L + T A G+ AD+YGR +I ++ V ++AF PN + FR G F + + CYV + E+V R + G ++ ++ + + P Y NW+ QL PS L++L +V PESPRWL + K + ++ L+ IA N
Sbjct: 138 STIVSEFDLVCVNAWMLDLTQAILNLGFLTG--AFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCN 315 HSP 2 Score: 55.0694 bits (131), Expect = 2.663e-7 Identity = 42/161 (26.09%), Postives = 81/161 (50.31%), Query Frame = 3
Query: 1038 FVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSL----------FFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD 1490
F+ G++E PGALL L++ R+ ++ + ++ L + W R ++G++ + + + V + +EL+PTT R+ F G++ LL + AAV++ +P++I+ +L I C + + +PETKG+ +PET+ D
Sbjct: 384 FISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAW---LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRL-AAVWLE--------LPLIIFGILASI-CGGLVMLLPETKGIALPETVDD 531
BLAST of slc22a-7 vs. Ensembl Human
Match: SLC22A15 (solute carrier family 22 member 15 [Source:HGNC Symbol;Acc:HGNC:20301]) HSP 1 Score: 87.4261 bits (215), Expect = 1.552e-17 Identity = 109/454 (24.01%), Postives = 207/454 (45.59%), Query Frame = 3
Query: 204 NETSHQIQISKDQC----TMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPV-FGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYH-ICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWR-LTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANIN-KMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPG-ALLSYL-SMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMI----FGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQE 1523
N++ +DQ +T NGS + +H FSS +I S++ L+ + Y ++S + + FG L+D++GRK + + +++ + F+P+ R +G + +V L E V + +AGS L+ +V + + L Y R+WR L L++L +++++L LF+PESPRWL + + + E+L IA N K+ + + + + F+ L +F F S++ + + L +IY ++ + GL+E P L YL + +F RKR ++ F G + + + L + K +F ++ +GK+ + + V +Y +EL+PT R++ G + + A +I L +P ++ F ++ L+ + +PET P+ ET D ++ R E
Sbjct: 58 NQSHGNQSAGEDQAFGDWLLTANGSEIH-KHVHFSSSF--TSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPE-KKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIV-FGATGLTSGLLSLLLPETLNSPLLETFSDLQVYSYRRLGE 506
BLAST of slc22a-7 vs. Ensembl Human
Match: SLC22A2 (solute carrier family 22 member 2 [Source:HGNC Symbol;Acc:HGNC:10966]) HSP 1 Score: 85.1149 bits (209), Expect = 2.152e-17 Identity = 54/191 (28.27%), Postives = 98/191 (51.31%), Query Frame = 3
Query: 300 EPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF------GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGF-SESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
E G +I+++++LVC ++ DL + +S+ F G++AD++GRK+ + + I A ++A +P + + FRL G S++ + I Y+ + E V + +R G F+ + +V + V Y +WR Q P+ ++L + +PESPRWL +NK + M ++ IA N L
Sbjct: 108 ETPGSSIVTEFNLVCANSWMLDL-----FQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSL 293
BLAST of slc22a-7 vs. Ensembl Celegans
Match: C06H5.6 (pep chromosome:WBcel235:V:17879844:17888968:-1 gene:WBGene00007394.1 transcript:C06H5.6a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06H5.6) HSP 1 Score: 97.4413 bits (241), Expect = 3.331e-21 Identity = 116/478 (24.27%), Postives = 221/478 (46.23%), Query Frame = 3
Query: 171 SIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRN---VAGSFFWLYGSVAMTVFPLTVYVT-RNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNK----KQQLMESL----QTIA-----NINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSM-FGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI--FDQRLLVKE-REQEYLE 1532
SI + +F+ ++ H + Q +TI+ V + + ++ TI SD+DLVC+Y+ + + ++ ++ +P L+D GR+ + +I L I A I A PN + FR G + +++ + +V ME V+ +FR+ V + W+ G + VF YV +NWR+ + P +L + F PES WL K K+ + ES+ QTI+ NI +D + + + + N+F+ + + + S+ + F+ GL+E P LS + FKRK ++ +S+ F ++F+ +V + ++ IF ++ S ++ +SQ +L +E PTT R++F G++ + + A Y+N+L P ++ ++++++ L+ + PETK +PE + FD L + ++Q+ LE
Sbjct: 80 SIDSAHFSPLVGDSCH---LQDTQLNITIDCLAVNGASYNYLADK-KSTITSDFDLVCEYQGMAEHATSIFLVGGMIVSPFVSQLSDILGRRPLFLIPLYISVAANLICAAAPNYLIFLLFRFISGVATTSFSMTGFVLCMESVSLEFRSLIPVLTTISWVGGYMLAGVF----YVFFKNWRVLYFAASVPGLLTIPFFWFTPESLHWLMTKQNDRKIKKYINESVAFNKQTISLIDCRNIQTVDNAPATTKTRTFRALFYPKIFVHVVINSFILIVMSGTYWALSLYSTELSEDETTGY---------FLSGLVELPAGFLSVFLLIAFKRKT-VSFYSLAFTAVFMLCTVYIPMQGNYKMIFPLLAKSTNS--IVWASQPLLY--SEATPTTIRNVFSGVVSFVGELGSIGAPYMNRLTAINQDAPAILISIMSIVAAFLV-LLQPETKNKKLPEDLDQFDAGPLFRGWKKQKDLE 534
BLAST of slc22a-7 vs. Ensembl Celegans
Match: C06H5.6 (pep chromosome:WBcel235:V:17879844:17888984:-1 gene:WBGene00007394.1 transcript:C06H5.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06H5.6) HSP 1 Score: 97.4413 bits (241), Expect = 3.331e-21 Identity = 116/478 (24.27%), Postives = 221/478 (46.23%), Query Frame = 3
Query: 171 SIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRN---VAGSFFWLYGSVAMTVFPLTVYVT-RNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNK----KQQLMESL----QTIA-----NINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSM-FGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI--FDQRLLVKE-REQEYLE 1532
SI + +F+ ++ H + Q +TI+ V + + ++ TI SD+DLVC+Y+ + + ++ ++ +P L+D GR+ + +I L I A I A PN + FR G + +++ + +V ME V+ +FR+ V + W+ G + VF YV +NWR+ + P +L + F PES WL K K+ + ES+ QTI+ NI +D + + + + N+F+ + + + S+ + F+ GL+E P LS + FKRK ++ +S+ F ++F+ +V + ++ IF ++ S ++ +SQ +L +E PTT R++F G++ + + A Y+N+L P ++ ++++++ L+ + PETK +PE + FD L + ++Q+ LE
Sbjct: 80 SIDSAHFSPLVGDSCH---LQDTQLNITIDCLAVNGASYNYLADK-KSTITSDFDLVCEYQGMAEHATSIFLVGGMIVSPFVSQLSDILGRRPLFLIPLYISVAANLICAAAPNYLIFLLFRFISGVATTSFSMTGFVLCMESVSLEFRSLIPVLTTISWVGGYMLAGVF----YVFFKNWRVLYFAASVPGLLTIPFFWFTPESLHWLMTKQNDRKIKKYINESVAFNKQTISLIDCRNIQTVDNAPATTKTRTFRALFYPKIFVHVVINSFILIVMSGTYWALSLYSTELSEDETTGY---------FLSGLVELPAGFLSVFLLIAFKRKT-VSFYSLAFTAVFMLCTVYIPMQGNYKMIFPLLAKSTNS--IVWASQPLLY--SEATPTTIRNVFSGVVSFVGELGSIGAPYMNRLTAINQDAPAILISIMSIVAAFLV-LLQPETKNKKLPEDLDQFDAGPLFRGWKKQKDLE 534
BLAST of slc22a-7 vs. Ensembl Celegans
Match: B0361.11 (Putative transporter B0361.11 [Source:UniProtKB/Swiss-Prot;Acc:Q7Z118]) HSP 1 Score: 93.5893 bits (231), Expect = 6.524e-20 Identity = 110/446 (24.66%), Postives = 200/446 (44.84%), Query Frame = 3
Query: 195 CQY-NET-----SHQIQISKDQCTMTINGSNVKCQHWTF---SSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMA-PVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAY-HICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFK----DNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI 1484
C+Y NET + QI+ + +NG T +++ ++ D+DL C + + + + ++ +++A P LAD+YGRK I + + +A +F+PN + + R IG +Y + V E +++ R + + S+ M L +T +WR I P + + L F+PESP WL KNK ++L + ++T +N ++PE ++++ K +FK ++L + F IS++ AI L + + L+E P L M RK MI I+ + + VT+ +D ++ F+++ + KV+ ++ATE FPT+ RSL F ++ I M + + Y+ + +IP ++ L + IS L F+ + ETK +P I
Sbjct: 82 CEYKNETIPISETCQIETESSKAFGNLNGEYCGIAENTLVNVTNQKASTNLLVDFDLSCSHWFFQEFGLTIFTIGAVIAVPFMSMLADRYGRKPIIVTTAILAFLANMAASFSPNFAIFLILRAFIGACSDSYLSVASVATCEYLSEKARAWITVVYNVAWSLGMVWTLLVTLMTDDWRWRYFIVSLPGVYGFALWYFLPESPHWLITKNKTEKLKKYIKTANRVN----NVSPEFNDCQQSSHHEEKHESFKALLGSKKLIWLLFANGFIEMVISLVYFAISFMSVELGGDQVQAFLYSSLIEIPAGLAVIPLMMKMGRK-MIVIWCLVFQTLALIGVTVF-LDSYE--FKLVIMLVAKVMATIIYSVHPIWATEQFPTSVRSLCFSLMNIPQSMGIIMSPYVKHIVMSPNWIPFVVIALFSFISATLAFM-LHETKNKKLPTDI 518
BLAST of slc22a-7 vs. Ensembl Celegans
Match: oct-2 (Organic Cation Transporter [Source:UniProtKB/TrEMBL;Acc:Q23501]) HSP 1 Score: 87.4261 bits (215), Expect = 9.125e-18 Identity = 62/228 (27.19%), Postives = 111/228 (48.68%), Query Frame = 3
Query: 195 CQYNETSH-QIQIS-----KDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF--GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFR-LCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
C Y E + I++S KD M G +C+ W + + +TI+++++ VCD + V + YS + F G+++D+YGRK F + + F+L ++ + R L +E+A YV ME+ +R++ GS + L Y+T++W + LI + I+ +++L F+PESPRWL + NK +Q + ++ + NK L
Sbjct: 249 CHYFERDYVHIKLSPWAQVKD---MNATGKINRCKEWEYDTSVMDRTIVTEWNRVCDNNW-SRAHVHMSYSLGYLVGCFVGGFISDRYGRKTAITGFGILTMLFGFLLTYSKEFEIFLVVRFLLAATNEAADLAAYVLCMEVTGTKYRSIVGSLIQAPWACGYAFLALIAYLTKSWTMIHLICVLLHIISLMLLYFLPESPRWLILNNKTKQAEKIIREACHYNKSRL 472 HSP 2 Score: 53.1434 bits (126), Expect = 4.743e-7 Identity = 40/138 (28.99%), Postives = 73/138 (52.90%), Query Frame = 3
Query: 1101 KRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQF-YGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKE 1511
KR +M+ +F +F+ SV + V + QS +IF + K + S + ++ +EL PT R+ G+ ++ M A+ YI L+ +PM I+ ++++ + + +PET+GLP+P+TI D +VK
Sbjct: 572 KRSQMLVLFG--SGLFLLTSVVM--VYRKQSTLALIFMLLSKACIQGSFNILYIFTSELNPTVVRNSAVGISSMVARMGAGASGYIAILSDVTMPLVPMTIFACFSLLAG-CLVLLLPETQGLPLPDTILDSVQMVKR 704
BLAST of slc22a-7 vs. Ensembl Celegans
Match: C44C10.3 (pep chromosome:WBcel235:X:11702525:11704500:1 gene:WBGene00008084.1 transcript:C44C10.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C44C10.3) HSP 1 Score: 80.8777 bits (198), Expect = 4.998e-16 Identity = 73/264 (27.65%), Postives = 116/264 (43.94%), Query Frame = 3
Query: 75 FYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQI----SKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVC-DYKYVGDLLVLLWYSTSLMAPV-FGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICY-VWLMEMVNKDFRNVAGSFF-WLYGSVAMTVFPLTVYVTRNWRLTQLI---SLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANI 833
FY+ + F + F+ L F G N+ SI P + C + ++ KD T +P ++ D+D VC + L+ Y L+ V FG L+DKYGRK I I+ + I ++ +PN R C G S + +C W++E + R V +FF W + V +TV Y+T+ WRL + L P++L +LI +PES WL K + +++ES + +A I
Sbjct: 2 FYDV-NRFHLCVFVTWQLVNFAVGQYIFNIF-SIHVPKWKCGDGPVTKDCKVYQSCPKDNLTFV---------------DPIFTSVAMDFDWVCGSSAHYQSFFSLVQYLGVLVGTVLFGTLSDKYGRKPIGILVIVIAIISLLGTGLSPNRQLLFIARFCSGLSIAGVLVCICAWILESILSHQRMVIRAFFNWGWTRVFITV---VCYLTQEWRLASYVCAACLVPALL-MLIFLIPESAIWLHSKGETAKMIESEKFMAKI 244
BLAST of slc22a-7 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0084598) HSP 1 Score: 92.0485 bits (227), Expect = 2.329e-19 Identity = 69/265 (26.04%), Postives = 124/265 (46.79%), Query Frame = 3
Query: 99 KVIAFLILSLPAFQYGSQFQN--------LLVSIQTP-NFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVG---DLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESA-YHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDLQ 851
K+ +L+ P F+ F+N L ++ P N C Y + + + + N + C + + + + +++++LVC ++ D L +L L + VFG L+DKYGRK I L I+ + + P ++ F RL +G + S + + YV MEMV D R AG F ++ SV + + Y +WR Q+ P ++++ + +PES RWL +K +K + ++Q A NK+++
Sbjct: 35 KLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKT-CSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFML--GVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEIS 296
BLAST of slc22a-7 vs. Ensembl Fly
Match: Orct2 (gene:FBgn0086365 transcript:FBtr0334869) HSP 1 Score: 92.0485 bits (227), Expect = 2.329e-19 Identity = 69/265 (26.04%), Postives = 124/265 (46.79%), Query Frame = 3
Query: 99 KVIAFLILSLPAFQYGSQFQN--------LLVSIQTP-NFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVG---DLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESA-YHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDLQ 851
K+ +L+ P F+ F+N L ++ P N C Y + + + + N + C + + + + +++++LVC ++ D L +L L + VFG L+DKYGRK I L I+ + + P ++ F RL +G + S + + YV MEMV D R AG F ++ SV + + Y +WR Q+ P ++++ + +PES RWL +K +K + ++Q A NK+++
Sbjct: 35 KLAGVFLLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKT-CSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFML--GVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEIS 296
BLAST of slc22a-7 vs. Ensembl Fly
Match: CG8925 (gene:FBgn0038404 transcript:FBtr0083253) HSP 1 Score: 81.2629 bits (199), Expect = 8.194e-16 Identity = 55/197 (27.92%), Postives = 106/197 (53.81%), Query Frame = 3
Query: 273 KCQHWTFSS-EPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGF-SESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDLQL 854
+C H+ FS + KT++ ++DLVC + + + A + GW++D++GR+ + F++I++V ILAF+ +++ + R+ IGF S + + +V ++E+V+ +R V G L +++ + Y+ R+WR QL P ++ + I F +PESPRWL + + +L ++ A +N L
Sbjct: 248 QCWHFEFSDVDGSAKTLVQEFDLVCGRDILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGLAYLIRDWRHLQLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASL 444
BLAST of slc22a-7 vs. Ensembl Fly
Match: CG8925 (gene:FBgn0038404 transcript:FBtr0113241) HSP 1 Score: 80.8777 bits (198), Expect = 8.936e-16 Identity = 54/197 (27.41%), Postives = 106/197 (53.81%), Query Frame = 3
Query: 273 KCQHWTFSS-EPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDLQL 854
+C H+ FS + KT++ ++DLVC + + + A + GW++D++GR+ + F++I++V ILAF+ +++ + R+ IGF+ + + +V ++E+V+ +R V G L +++ + Y+ R+WR QL P ++ + I F +PESPRWL + + +L ++ A +N L
Sbjct: 184 QCWHFEFSDVDGSAKTLVQEFDLVCGRDILSLVETCFLVGAAAGAVLSGWISDRFGRRHTLMAFVTIQSVFGGILAFSTSVAMFMSLRVIIGFASMTVTVVSFVLVVELVSGKWRTVIGILNILPVAISYVLSAGLAYLIRDWRHLQLAISWPWLIMLSIWFWLPESPRWLLAQGRLDELCGLIERAARMNGTSASL 380
BLAST of slc22a-7 vs. Ensembl Fly
Match: Balat (gene:FBgn0033778 transcript:FBtr0087815) HSP 1 Score: 79.337 bits (194), Expect = 2.810e-15 Identity = 58/227 (25.55%), Postives = 109/227 (48.02%), Query Frame = 3
Query: 183 PNFTCQYNETSHQIQISKDQCTMTINGSNVKCQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWR-LTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQ 851
P+ Q E ++Q Q V CQH W + + T++ +++LVCD ++ L ++++ L+ VFG+L D +GR+ +L +E +A AF N + + R +G + A YV +E+V + R + S+ + V +Y+ R+WR L+ +S+ +L+ +PESPRWL K ++ ++ L+ +A +N + +
Sbjct: 102 PDLLRQQAEDLLKLQPDTTQV--------VPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVN 320
BLAST of slc22a-7 vs. Ensembl Zebrafish
Match: slc22a2 (solute carrier family 22 member 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2167]) HSP 1 Score: 110.538 bits (275), Expect = 3.919e-25 Identity = 109/447 (24.38%), Postives = 206/447 (46.09%), Query Frame = 3
Query: 312 KTIMSDYDLVC-DYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRK---MISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFS-ESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNN--------FLFLASTXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIIL-LMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD----QRLLVKEREQEYLEYMYNRSDVVNSD 1568
++ ++++DLVC D YV L + + G+LADKYGR +++ F+ + + ++A +PN S + FR GF + + + YV + E+V D R G + L+ S+ + + PL Y NWR Q++ P I ++ F+PESPRWL +NK + +E ++IA N+ L S K KD+N F+ L T+ + + +++ +++ L +L N+Y+ + G++E P A L L++ R+ ++ ++ + W + +G++ + + + V+ TEL+PT R+L + + + + A + +L + +P++I+ L ++ L+ + +PETKG+P+PETI D R ++ + LE + N D
Sbjct: 134 QSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTNFFIGVTGI---LVATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRRTVGVTYQLFFSMGILLLPLLAYFITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKENRKTL---------------SKKIETLKDDNIDSGSTASFMDLFKTAKLRTYTFILSFNWFTSAVVYQGLIMRLGILGGNVYVDFLISGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLITAFIPDSMFW---LKSAVACVGRLGITMAFEMVVFVNTELYPTVIRNLGVSVCSTLCDVGGIVAPFLLYRLAVIWLELPLIIFGALAFVAGGLV-LLLPETKGVPLPETIDDIEHPNRNKENPQQSQQLENLMTSDVTKNKD 558
BLAST of slc22a-7 vs. Ensembl Zebrafish
Match: slc22a4 (solute carrier family 22 member 4 [Source:ZFIN;Acc:ZDB-GENE-040426-1517]) HSP 1 Score: 108.997 bits (271), Expect = 1.146e-24 Identity = 109/445 (24.49%), Postives = 208/445 (46.74%), Query Frame = 3
Query: 207 ETSHQIQISKDQCTMTINGSNVKCQ----HWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF-GWLADKYGRKMISIIFLSIETVATFILAFTPNLS--SHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSFFWLYGS-VAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXM--------FVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIF-LSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI 1484
+T Q+ + + +N S ++ + W++S E + TI++++DLVC+ +Y G L +++ L+ G ++D+YGR+ + ++++T+ I F+P+ S I+F +GFS S Y + YV E+++ R + GS GS + FPL Y R+WR L + +LY L F+PESPRWL + + + L+ A N++ PE I +E+ K K + L++ + + I L+ ++ ++ F+ ++E P +++ L + F R+ + G IF + + +++ + M +GK+ V + V +ELFPT R++ G + + + +I L +Y +IP ++ L + S ++ + +PE+KG +PETI
Sbjct: 87 DTLRQLSMLNYTPNVEVNLSQIETEPCVDGWSYSQEFYQSTIVTEWDLVCEREYKGPLTSSIYFCGVLVGTFLSGQMSDRYGRRPVLFAMMALQTITILIQMFSPSWEVFSAIYF--FVGFSGFSNYVVAYVLGSEILSPASRVLFGSLGVFMGSGIGQMFFPLAAYFIRSWRWLVLTNALTGLLYFPLWWFIPESPRWLLSQGRTAEAEAVLRRAAEKNRVT---APEVIFSSSEIEEAAKKRIQKHSILDILSNCNAVSTILICSLLWMVITMSYYALILNTTNLHGNPYLNFFLSAVVEVPAYIIAALLLRFCSRRICQASTLLLGGALIFIIQLIPTELQGLSTALEM----LGKLCVTAAFCVVYAVTSELFPTVVRNMAMGSCSMTARIGSIISPFIIYLGNYYRYIPYIVIGGLALFS-GVMSLLLPESKGKVLPETI 521
BLAST of slc22a-7 vs. Ensembl Zebrafish
Match: slc22a6l (solute carrier family 22 member 6, like [Source:NCBI gene;Acc:404609]) HSP 1 Score: 99.7525 bits (247), Expect = 9.595e-22 Identity = 122/558 (21.86%), Postives = 229/558 (41.04%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQ--FQNLLVSIQTPNFTCQYN-----ETSHQIQISKDQCTMTINGSNVKCQH---------------------------------WTFSSEPFGKTIMSDYDLVCDYK---------YVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHI-CYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWR-LTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANIN-------KMDLQLTPXXXXXXXXXXXS--NKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI--FDQRLLVKEREQEYLEYM 1538
M +++ F+V+ +LS+P S QN + ++ P CQ + ++ + + + + +NG +C+ W ++ TI++++DLVCDY+ Y+G +LV A VFG L+D++GR+++ +I + + +AF+ + + FR+C G + S + + ++E + R V G+ + + Y R+WR LT +SL + ++ + ES RWL + K +Q +++L+T+A IN K+DL++ E +K E + + + + + + FS S + +DL +IY+ + G ++ P ++ + M R+ + I I +++ V + R IGK + S +YA EL+PT R G + ++ A + L Y +IP IY ++S F F+PET P+P+TI D R L + + E +
Sbjct: 1 MAFSDLLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAV--PPHHCQPHANLSMSSTDAMDVLRATVPLGLNGKLERCKRYTTPQWQILSLNTSESLWDESMAETETQSCEDGWFYNMTEMSSTIITEWDLVCDYRALKQMSQTTYMGGVLV--------GAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFSTSFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTGTGYCYTTGQLILAAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKKPEQAVKNLKTVARINGRSAEGDKIDLEMLQESMKKEMACSKGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLSMDLQKFGVSIYLIQIIFGAVDIPAKIIVTICMSMLGRRPSQCGALVLAGIMILINLL---VPSDLQMLRTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGGAPIVSGIFAF-FLPETLSQPLPDTIQDIDDRGLARTNSKRLPEKL 544
BLAST of slc22a-7 vs. Ensembl Zebrafish
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92]) HSP 1 Score: 98.9821 bits (245), Expect = 1.870e-21 Identity = 102/429 (23.78%), Postives = 205/429 (47.79%), Query Frame = 3
Query: 279 QHWTFSSEPFGKTIMSDYDLVCDYKYVGDL-LVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGF-SESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFV-PESPRWLCVKNKKQQLMESLQTIANINK---------MDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYI-NKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD-QRLLVKEREQE 1523
+ WTF+ TI++++ LVC+ ++ DL V L + A V G+LAD++GRK I + V+ + F+P +FFR GF ++ A+ YV ++E + R + S+ + + P Y +WR QL P+ ++++ +V PESPRWL + K ++ + +++IA NK MDL + +E + + K+ K + + F+ + + F+ +++ +++ L + N+++ + ++E P L+ Y + R+ ++ + G +S W R +G++ V ++ V TEL+PT R+L + + A +I +L + +P+L+Y +++++ L+ + +PE KG+ +PET+ D + L + + +E
Sbjct: 114 EGWTFNENR--TTIVTEFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGRKSCFIASIFGLGVSGTCIIFSPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKFVSVMSRTFYSLGLVLLPALAYYIPSWRNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFHEMDLLIEKQEEIMRPSYKDLFKTPKMRKHTFILIYA-----WFTGAVVFQGLVLRLGITGDNVFLDFLISAVVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAVPFISPNISW---LRRTIAIVGRLAVAIGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLLVYGVMSVLYSGLV-MLLPEMKGVDLPETVDDVENLRSRHKRKE 531
BLAST of slc22a-7 vs. Ensembl Zebrafish
Match: si:dkey-166k12.1 (si:dkey-166k12.1 [Source:ZFIN;Acc:ZDB-GENE-120215-78]) HSP 1 Score: 97.8265 bits (242), Expect = 3.679e-21 Identity = 66/214 (30.84%), Postives = 108/214 (50.47%), Query Frame = 3
Query: 237 DQCTMT--INGS-NVKCQ-HWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHI-CYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFV-PESPRWLCVKNKKQQLMESLQTIANINKMDLQLT 857
D CT +N S C+ W +S E F T ++++DLVCD + + L ++ L+ A VFG +AD+YGR+ ++ L+++TV AF PN ++ R IG + S I +V E R +AG F + + ++ R+WR QL P L++ ++V P S RWL V N+K++ ++ L+ A++N L T
Sbjct: 80 DACTAASGVNRSARTNCETGWVYSHEVFQSTTVTEWDLVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNFPVYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLAGIFTDYFFGFGYMLLAGVAFLIRDWRKLQLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPT 293 HSP 2 Score: 51.6026 bits (122), Expect = 1.866e-6 Identity = 44/151 (29.14%), Postives = 69/151 (45.70%), Query Frame = 3
Query: 1038 FVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD 1490
F+ GL+E P L L + RK +++F + G L++TL + R +GK + S + VY+ ELFPT R G+ + M A IN L + +PMLI F + + + +PET P+P++I D
Sbjct: 356 FMFGLVEIPARTL-VLVLLPCSRKIPLSVFLVVGGGACLLTLTLPADS---AHVRTALAMVGKFGITASFAIIYVYSAELFPTVLRQTGIGVSSMFARMGGVLAPLINLLGRHTPVVPMLI-FGSTPLLAAALALALPETARQPLPDSIHD 501
BLAST of slc22a-7 vs. Ensembl Xenopus
Match: ENSXETT00000022866.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 126.331 bits (316), Expect = 2.270e-30 Identity = 124/530 (23.40%), Postives = 219/530 (41.32%), Query Frame = 3
Query: 96 FKVIAFLILSLPAFQYGSQ--FQNLLVSIQTPNFTCQYNETSHQIQISKD------QCTMTINGSNVKCQH-----------------------------WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMF---------VLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYM 1538
F++ ++L P S QN +I P+ C+ N+T +Q + + + NG +C W +S + F TI++++DLVC K L ++ L+ A + G L+D+YGR+ + I V+ AF+PN S+ FR G + S + L+ E V R V G+ + + Y R+WR QL P +Y L + PES RWL + K ++ ++ ++ +AN+N + ++ K+ +A + + L T+ S ++ + + + F + G ++FP L+S +M + RK + + G I I ++ + ++ Q++ R GK + S + +Y TEL+PT R GM + + A + L + Y F+P+LIY +IS +F F+PET P+P+TI + + +VK + L M
Sbjct: 16 FQITQVVLLCFPILLMASHNLLQNFSAAI--PDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVP--NELQTV-RTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVF-FLPETVNKPLPDTIEEHKDIVKSLKLHSLALM 539
BLAST of slc22a-7 vs. Ensembl Xenopus
Match: ENSXETT00000036031.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 123.25 bits (308), Expect = 2.601e-29 Identity = 124/540 (22.96%), Postives = 221/540 (40.93%), Query Frame = 3
Query: 96 FKVIAFLILSLPAFQYGSQ--FQNLLVSIQTPNFTCQYNETSHQIQISKD------QCTMTINGSNVKCQH-----------------------------WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMF---------VLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSD 1568
F++ ++L P S QN +I P+ C+ N+T +Q + + + NG +C W +S + F TI++++DLVC K L ++ L+ A + G L+D+YGR+ + I V+ AF+PN S+ FR G + S + L+ E V R V G+ + + Y R+WR QL P +Y L + PES RWL + K ++ ++ ++ +AN+N + ++ K+ +A + + L T+ S ++ + + + F + G ++FP L+S +M + RK + + G I I ++ + ++ Q++ R GK + S + +Y TEL+PT R GM + + A + L + Y F+P+LIY +IS +F F+PET P+P+TI +E E+ L+ + ++ D
Sbjct: 16 FQITQVVLLCFPILLMASHNLLQNFSAAI--PDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVP--NELQTV-RTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVF-FLPETVNKPLPDTI-------EEVEKGELDVCKTKESHISQD 542
BLAST of slc22a-7 vs. Ensembl Xenopus
Match: ENSXETT00000036038.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 122.479 bits (306), Expect = 5.016e-29 Identity = 121/525 (23.05%), Postives = 216/525 (41.14%), Query Frame = 3
Query: 96 FKVIAFLILSLPAFQYGSQ--FQNLLVSIQTPNFTCQYNETSHQIQISKD------QCTMTINGSNVKCQH-----------------------------WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMF---------VLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQE 1523
F++ ++L P S QN +I P+ C+ N+T +Q + + + NG +C W +S + F TI++++DLVC K L ++ L+ A + G L+D+YGR+ + I V+ AF+PN S+ FR G + S + L+ E V R V G+ + + Y R+WR QL P +Y L + PES RWL + K ++ ++ ++ +AN+N + ++ K+ +A + + L T+ S ++ + + + F + G ++FP L+S +M + RK + + G I I ++ + ++ Q++ R GK + S + +Y TEL+PT R GM + + A + L + Y F+P+LIY +IS +F F+PET P+P+TI + + ++E
Sbjct: 16 FQITQVVLLCFPILLMASHNLLQNFSAAI--PDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVP--NELQTV-RTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVF-FLPETVNKPLPDTIEEVEKGINAPKKE 534
BLAST of slc22a-7 vs. Ensembl Xenopus
Match: ENSXETT00000022873.1 (solute carrier family 22 (organic anion transporter), member 8 [Source:NCBI gene;Acc:100490266]) HSP 1 Score: 122.094 bits (305), Expect = 7.200e-29 Identity = 120/512 (23.44%), Postives = 211/512 (41.21%), Query Frame = 3
Query: 96 FKVIAFLILSLPAFQYGSQ--FQNLLVSIQTPNFTCQYNETSHQIQISKD------QCTMTINGSNVKCQH-----------------------------WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMF---------VLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETI 1484
F++ ++L P S QN +I P+ C+ N+T +Q + + + NG +C W +S + F TI++++DLVC K L ++ L+ A + G L+D+YGR+ + I V+ AF+PN S+ FR G + S + L+ E V R V G+ + + Y R+WR QL P +Y L + PES RWL + K ++ ++ ++ +AN+N + ++ K+ +A + + L T+ S ++ + + + F + G ++FP L+S +M + RK + + G I I ++ + ++ Q++ R GK + S + +Y TEL+PT R GM + + A + L + Y F+P+LIY +IS +F F+PET P+P+TI
Sbjct: 16 FQITQVVLLCFPILLMASHNLLQNFSAAI--PDHKCKANDTGYQSNSTDETGYERLSAPLDANGQPDRCLEYVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTIITEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSPNYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVRTVTGTLAGFSYTAGQLLLAGLAYGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKKEEGEKITLESLKSEMIKELASAKSSYSVIDLVRTNTIRRISCALSLVWFSTSFAYYGLAMDLQKFNVSIYLIQVIFGAVDFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVP--NELQTV-RTSLAVFGKGCLAASFSCIFLYTTELYPTVIRQSGLGMCSTMARIGGIVAPLVKILGELYPFVPLLIYGGAPIISGLCVF-FLPETVNKPLPDTI 521
BLAST of slc22a-7 vs. Ensembl Xenopus
Match: emc2 (ER membrane protein complex subunit 2 [Source:Xenbase;Acc:XB-GENE-484487]) HSP 1 Score: 100.908 bits (250), Expect = 7.174e-22 Identity = 113/538 (21.00%), Postives = 234/538 (43.49%), Query Frame = 3
Query: 60 ENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQH---------------------------------WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSF-FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF--VPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRK-RMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIY----FLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKERE 1517
+ +F + F+V F +LS G + + TP C E+++ ++ +G + +C+ W +S + TI+++++LVC+ + G L L++ L+ V G ++D++GRK + ++++T + I F+ N + +G + S Y ++ E+++K R + + ++ ++ + PL Y R+WR T L++LT L+ + L+ +PESPRWL + + Q+ + ++ A N +TP + T + K K + FL L T + + ++ + ++ L + Y++ F+ ++E P ++++L + F R+ + + G + +F+ + V + I ++ +GK + ++ V VY EL+PT R++ G + M + Y L + F+P ++ L+ M + CL PE+ G+P+P+TI ++ L VK +
Sbjct: 5 DQATAFLGEWGPFQVSVFFLLSASIIPNGFTGLSAVFLAATPEHRCHVPESANLSAAWRNASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWNLVCENDWKGPLTTSLFFVGVLIGSFVSGQMSDRFGRKKVLFATMAVQTGFSIIQVFSVNWEMFTALFIIVGMGQISNYVAAFILGAEILDKSVRIIFSTLGVCIFYAIGYMLLPLFAYFIRDWR-TLLLALTIPGLFCIPLWWIIPESPRWLISQGRFQEAEDIIRKAAKKNG----ITPPDSIFNFTELQEQKELTHKSHTFLDLLKTRNIRIITFLSILLWMIISVGYFGLSLNTPNLHGDPYVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLLFIQL----VPQELGILSIVLVMLGKFGITSAFSMVYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLCL-----PESHGMPLPDTI-EEMLRVKGEQ 527
BLAST of slc22a-7 vs. Ensembl Mouse
Match: Slc22a5 (solute carrier family 22 (organic cation transporter), member 5 [Source:MGI Symbol;Acc:MGI:1329012]) HSP 1 Score: 106.301 bits (264), Expect = 9.850e-24 Identity = 113/462 (24.46%), Postives = 219/462 (47.40%), Query Frame = 3
Query: 186 NFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSF----FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNK--------WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMF--GSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQ 1520
NF+ E + + + + ++G W + + F TI++++DLVC + L L++ LM + G L+D++GRK + + + ++T +F+ F+ N + +G + S Y +V E+++K R + + F+ +G V PL Y R+WR+ L P +L L F+PESPRWL + + ++ ++ A IN + + P I ++ N ++ + N + S+ +IS+ + +D L +IY++ F+L +E P +L++L + + R+ I+ ++F GS+ +F+ + S++ + M +GK + ++ V VY EL+PT R++ G+ + + Y L + F+P ++ L +++ L +F PE+ G+P+P+TI DQ L VK +Q
Sbjct: 91 NFSELGLEPGRDVDLEQLEQESCLDG-------WEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFG---FMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGI---VAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISA-ALFLGGSVLLFMQLVPSELFYLSTALVM----VGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT-LFFPESFGVPLPDTI-DQMLRVKGIKQ 532
BLAST of slc22a-7 vs. Ensembl Mouse
Match: Slc22a21 (solute carrier family 22 (organic cation transporter), member 21 [Source:MGI Symbol;Acc:MGI:1929481]) HSP 1 Score: 97.4413 bits (241), Expect = 6.997e-21 Identity = 111/436 (25.46%), Postives = 202/436 (46.33%), Query Frame = 3
Query: 285 WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSF----FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIANINKM-------DLQLTPXXXXXXXXXXXSNK-WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTL------SKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYL 1529
W + + F TI++++DLVC + L +Y L+ + G L+D++GRK I + +++ T +FI F+ N +G S Y +V EM++K R + + F+ +G V PL Y R WR L P +L L F+PESPRWL + + ++ ++ A IN + D T + +S+ ++ + N L S+ +IS+ + +D L+ NIY++ F+L +E P +L++L + R+ +SM GS+F+ SV L S + + M +GK + ++ V VY EL+PT R++ G+ + + Y L + +P ++ L +++ +I +F PE+ G+ +PETI + + + K ++++ L
Sbjct: 117 WEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFG---FMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRR-----YSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVM----VGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILT-AIITLFFPESSGVSLPETIDEMQKVKKLKQRQSL 539
BLAST of slc22a-7 vs. Ensembl Mouse
Match: Slc22a20 (solute carrier family 22 (organic anion transporter), member 20 [Source:MGI Symbol;Acc:MGI:2685809]) HSP 1 Score: 97.0561 bits (240), Expect = 7.643e-21 Identity = 94/424 (22.17%), Postives = 192/424 (45.28%), Query Frame = 3
Query: 285 WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRK---MISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLI-LFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVL---------GLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKE 1511
W + F TI+ ++DLVC+ + + DL ++ S L+ A +FG LAD+ GRK + S + L++ AT A+ + S++ FR +G + S + + L+ E + R VAG ++ + Y+ R WR Q P +++ L ++PES RWL + K QQ +++LQ +A +N + ++ + + + N+ L L T + ++ + + + F L G+++ P L++ +M + R+ ++ F + + + ++ + + Q++ R + ++GK + +S V ++ EL+PT R + G + + A I L + +P + + ++++ + F+ ET+ +P+ ETI VK+
Sbjct: 111 WVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAAT---AYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEFASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMP--EDLQTL-RTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVPLVETIAAMERRVKQ 528
BLAST of slc22a-7 vs. Ensembl Mouse
Match: Slc22a3 (solute carrier family 22 (organic cation transporter), member 3 [Source:MGI Symbol;Acc:MGI:1333817]) HSP 1 Score: 92.4337 bits (228), Expect = 8.003e-20 Identity = 57/182 (31.32%), Postives = 97/182 (53.30%), Query Frame = 3
Query: 315 TIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF--GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIG-FSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
TI+S +DLVC ++ DL + + +A F G+ AD+YGR +I +I + ++AF PN S + FR G F + A+ C+V + E+V R + G ++ ++ + + P Y T +W+ QL PS L++L + VPESPRWL + + ++ ++ L+ +A N L
Sbjct: 134 TIVSQFDLVCSNAWMLDLTQAI-LNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHL 314
BLAST of slc22a-7 vs. Ensembl Mouse
Match: Slc22a3 (solute carrier family 22 (organic cation transporter), member 3 [Source:MGI Symbol;Acc:MGI:1333817]) HSP 1 Score: 93.9745 bits (232), Expect = 8.068e-20 Identity = 57/183 (31.15%), Postives = 97/183 (53.01%), Query Frame = 3
Query: 312 KTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF--GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIG-FSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
TI+S +DLVC ++ DL + + +A F G+ AD+YGR +I +I + ++AF PN S + FR G F + A+ C+V + E+V R + G ++ ++ + + P Y T +W+ QL PS L++L + VPESPRWL + + ++ ++ L+ +A N L
Sbjct: 133 STIVSQFDLVCSNAWMLDLTQAI-LNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHL 314 HSP 2 Score: 54.6842 bits (130), Expect = 2.035e-7 Identity = 41/161 (25.47%), Postives = 81/161 (50.31%), Query Frame = 3
Query: 1038 FVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSL----------FFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD 1490
F+ GL+E PGALL L++ R+ ++ + ++ L + W R ++G++ + + + V + +EL+PTT R+ F G++ LL + AA+++ +P++I+ +L + C + + +PETKG+ +PET+ D
Sbjct: 379 FISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPW---LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRL-AAIWLE--------LPLIIFGILASV-CGGLVMLLPETKGIALPETVED 526
BLAST of slc22a-7 vs. UniProt/SwissProt
Match: sp|Q9Z0E8|S22A5_MOUSE (Solute carrier family 22 member 5 OS=Mus musculus OX=10090 GN=Slc22a5 PE=1 SV=1) HSP 1 Score: 106.301 bits (264), Expect = 6.890e-23 Identity = 113/462 (24.46%), Postives = 219/462 (47.40%), Query Frame = 3
Query: 186 NFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSF----FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNK--------WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMF--GSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQ 1520
NF+ E + + + + ++G W + + F TI++++DLVC + L L++ LM + G L+D++GRK + + + ++T +F+ F+ N + +G + S Y +V E+++K R + + F+ +G V PL Y R+WR+ L P +L L F+PESPRWL + + ++ ++ A IN + + P I ++ N ++ + N + S+ +IS+ + +D L +IY++ F+L +E P +L++L + + R+ I+ ++F GS+ +F+ + S++ + M +GK + ++ V VY EL+PT R++ G+ + + Y L + F+P ++ L +++ L +F PE+ G+P+P+TI DQ L VK +Q
Sbjct: 91 NFSELGLEPGRDVDLEQLEQESCLDG-------WEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFG---FMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGI---VAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISA-ALFLGGSVLLFMQLVPSELFYLSTALVM----VGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT-LFFPESFGVPLPDTI-DQMLRVKGIKQ 532
BLAST of slc22a-7 vs. UniProt/SwissProt
Match: sp|O70594|S22A5_RAT (Solute carrier family 22 member 5 OS=Rattus norvegicus OX=10116 GN=Slc22a5 PE=1 SV=1) HSP 1 Score: 103.219 bits (256), Expect = 5.687e-22 Identity = 112/462 (24.24%), Postives = 217/462 (46.97%), Query Frame = 3
Query: 186 NFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSF----FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNK--------WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMF--GSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQ 1520
NF+ E + + + + ++G W ++ + F TI++++DLVC + L L++ LM + G L+D++GRK + + + ++T +F+ F+ N + +G + S Y +V E+++K R + + F+ +G V PL Y R+WR+ L P +L L F+PESPRWL + + ++ ++ A N + + P I ++ N ++ + N + S+ +IS+ + +D L +IY++ F+L +E P +L++L + R+ I+ ++F GS+ +F+ + S++ + M +GK + ++ V VY EL+PT R++ G+ + + Y L + F+P ++ L +++ L +F PE+ G P+P+TI DQ L VK +Q
Sbjct: 91 NFSALGLEPGRDVDLEQLEQENCLDG-------WEYNKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFG---FMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGI---VAPSTIFDPSELQDLNSKKPQSHHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISA-ALFLGGSVLLFIQLVPSELFYLSTALVM----VGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT-LFFPESFGAPLPDTI-DQMLRVKGIKQ 532
BLAST of slc22a-7 vs. UniProt/SwissProt
Match: sp|Q9WTN6|S22AL_MOUSE (Solute carrier family 22 member 21 OS=Mus musculus OX=10090 GN=Slc22a21 PE=2 SV=1) HSP 1 Score: 97.4413 bits (241), Expect = 4.894e-20 Identity = 111/436 (25.46%), Postives = 202/436 (46.33%), Query Frame = 3
Query: 285 WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSF----FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIANINKM-------DLQLTPXXXXXXXXXXXSNK-WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTL------SKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYL 1529
W + + F TI++++DLVC + L +Y L+ + G L+D++GRK I + +++ T +FI F+ N +G S Y +V EM++K R + + F+ +G V PL Y R WR L P +L L F+PESPRWL + + ++ ++ A IN + D T + +S+ ++ + N L S+ +IS+ + +D L+ NIY++ F+L +E P +L++L + R+ +SM GS+F+ SV L S + + M +GK + ++ V VY EL+PT R++ G+ + + Y L + +P ++ L +++ +I +F PE+ G+ +PETI + + + K ++++ L
Sbjct: 117 WEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFG---FMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRR-----YSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVM----VGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILT-AIITLFFPESSGVSLPETIDEMQKVKKLKQRQSL 539
BLAST of slc22a-7 vs. UniProt/SwissProt
Match: sp|Q80UJ1|S22AK_MOUSE (Solute carrier family 22 member 20 OS=Mus musculus OX=10090 GN=Slc22a20 PE=1 SV=1) HSP 1 Score: 97.0561 bits (240), Expect = 5.347e-20 Identity = 94/424 (22.17%), Postives = 192/424 (45.28%), Query Frame = 3
Query: 285 WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRK---MISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLM-EMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLI-LFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVL---------GLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKE 1511
W + F TI+ ++DLVC+ + + DL ++ S L+ A +FG LAD+ GRK + S + L++ AT A+ + S++ FR +G + S + + L+ E + R VAG ++ + Y+ R WR Q P +++ L ++PES RWL + K QQ +++LQ +A +N + ++ + + + N+ L L T + ++ + + + F L G+++ P L++ +M + R+ ++ F + + + ++ + + Q++ R + ++GK + +S V ++ EL+PT R + G + + A I L + +P + + ++++ + F+ ET+ +P+ ETI VK+
Sbjct: 111 WVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAAT---AYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEFASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMP--EDLQTL-RTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVPLVETIAAMERRVKQ 528
BLAST of slc22a-7 vs. UniProt/SwissProt
Match: sp|Q9WTW5|S22A3_MOUSE (Solute carrier family 22 member 3 OS=Mus musculus OX=10090 GN=Slc22a3 PE=2 SV=1) HSP 1 Score: 93.9745 bits (232), Expect = 5.644e-19 Identity = 57/183 (31.15%), Postives = 97/183 (53.01%), Query Frame = 3
Query: 312 KTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF--GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIG-FSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
TI+S +DLVC ++ DL + + +A F G+ AD+YGR +I +I + ++AF PN S + FR G F + A+ C+V + E+V R + G ++ ++ + + P Y T +W+ QL PS L++L + VPESPRWL + + ++ ++ L+ +A N L
Sbjct: 133 STIVSQFDLVCSNAWMLDLTQAI-LNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHL 314 HSP 2 Score: 54.6842 bits (130), Expect = 1.424e-6 Identity = 41/161 (25.47%), Postives = 81/161 (50.31%), Query Frame = 3
Query: 1038 FVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSL----------FFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD 1490
F+ GL+E PGALL L++ R+ ++ + ++ L + W R ++G++ + + + V + +EL+PTT R+ F G++ LL + AA+++ +P++I+ +L + C + + +PETKG+ +PET+ D
Sbjct: 379 FISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPW---LRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRL-AAIWLE--------LPLIIFGILASV-CGGLVMLLPETKGIALPETVED 526
BLAST of slc22a-7 vs. TrEMBL
Match: A0A0H3YF34 (Slc22a-7 OS=Schmidtea mediterranea OX=79327 GN=slc22a-7 PE=2 SV=1) HSP 1 Score: 983.786 bits (2542), Expect = 0.000e+0 Identity = 525/525 (100.00%), Postives = 525/525 (100.00%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRKFR 1625
MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKESNKWNAFKDNNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRKFR
Sbjct: 1 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKESNKWNAFKDNNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRKFR 525
BLAST of slc22a-7 vs. TrEMBL
Match: A0A0H3YJ93 (Slc22a-1 OS=Schmidtea mediterranea OX=79327 GN=slc22a-1 PE=2 SV=1) HSP 1 Score: 528.48 bits (1360), Expect = 1.347e-180 Identity = 272/528 (51.52%), Postives = 382/528 (72.35%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDV-VNSDRE----DSDASSEMSQLINRK 1619
MILE+++ YNK++TFK +AF ILSLP+FQ+ SQ QN+L+S TP +TC YN + +I IS DQC M I+GS + C W FS EP G+T+MSD+ LVCDYK +GD+++++WYSTS+ P+ GW +DK+GRK ++I L +ET++TF ++FTP+++S+I RL IG S + ++ CYVWLMEMV+ +FR +GSF W YG +A VFPLT Y T++WR+TQLISL P+ILY LIL PESPRWLCV N+K +L++SL IA INK+D + ++I + KT E N W A KD F + S VFSI+++ +AI ++L +LS+N+YISMF+LGLMEFPG LLSY+S+ FF+RK + GSIFI +SV S+ WQ + R+IFG I K+ V T +Q +VY +EL PT+HRSL F +Q+ L + TAAVYINKL+ F+PM+IYF+L ++ C+I++++PETK LPIPET+ DQ++L +E+E+L+YM + ++ V SD + S+ S+E S LINRK
Sbjct: 1 MILEDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTCLYNSSFSKISISADQCNMIIDGSTIVCNKWNFSYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYDQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILLSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAVYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREMEVESDLDLDLLKSNESTEESHLINRK 528
BLAST of slc22a-7 vs. TrEMBL
Match: A0A0H3YFD1 (Slc22a-9 OS=Schmidtea mediterranea OX=79327 GN=slc22a-9 PE=2 SV=1) HSP 1 Score: 410.994 bits (1055), Expect = 1.819e-134 Identity = 227/528 (42.99%), Postives = 357/528 (67.61%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNR-----SDVVNSDREDSDASSEMSQLINRK 1619
M L+N++S NK TFK++AF ILSLP FQ SQ QN+L ++ PNF C++N S I +SKDQC++ +NG+ + C+ W FS P G T++SD+ LVCD +Y+GD+++++WY+ L+ P+ G+++D++GRK I I+ L +ET ++ +LA +PN ++++ FR+ +G S SA +I VWL+E V+ +FR GSF+W Y +VA VFP+T ++ R+WRL+QL +L PS+ Y+ I F+PESPRWLCV N+K ++MESL+ ++ IN++ + ++I +E KE N A KD +F + T+LF FSI+++ S++L+D+ +LSSN+Y+S+F+LGLME P LLSY + + KRK + GS+ +F+S+ SK QS+ R++ G + K+ + + +Q ++VY ELFPTTHRS +L I ++ + AV IN+L+ F+P LIYF I +++ +PETK LPIPET+ D ++L +E+E++ YM N+ + V NSD + S+ +E S+LI K
Sbjct: 1 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCKFNSKSKFI-VSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPLVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSASAVYISIVWLIESVSIEFRPFIGSFYWFYWTVAYMVFPITSFLARDWRLSQLFTLIPSVFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSITALFCAFSINLIYSSMLVDIGILSSNMYLSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNNTVDNSDEKSSENLNEKSKLITGK 527
BLAST of slc22a-7 vs. TrEMBL
Match: A0A267FBR0 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009851g1 PE=4 SV=1) HSP 1 Score: 166.777 bits (421), Expect = 3.014e-41 Identity = 129/516 (25.00%), Postives = 251/516 (48.64%), Query Frame = 3
Query: 111 FLILSLPAFQYGSQFQNLLVSIQTPNFTC-QYNETSHQIQISKDQCTMT-INGS-------NVKCQHWTFS-SEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLI-LFVPESPRWLCVKNKKQQLMESLQTIANIN--KMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRK 1619
FL LS +F+ + +++++ F C Q N + + Q + C+++ + G N C + + + K+++ +YDLVCD K+ ++ +++ + +FG L DK GRK I I+ + + T + AF P + IF R GF + Y+ + + EM + R V G+ +WL+ V + VY+ + W QL S + Y++I + VPESPRWL +K + ++ ++ L+ IA N K + +++ + + N + + + ++ + D +++NI +++ + G +E P + + +L + RK I ++ S F ++V + +I + + +GK L+ T V+A E+FPT+ R+ + + +++ A IN L+ F+P LI+ + +++S L + +PETKGLP+PET+ LV+ RE+++ ++R + S +D D + SQ I ++
Sbjct: 21 FLALSFTSFKAVLDLELMVLTLHESKFRCAQQNSSDYVAQNYSEHCSISRLVGDDTNFTLINETCTKFDYQHGDVISKSMVEEYDLVCDRKHYATGMMSVFFLGCALGMLFGTLGDKIGRKKILIVCGVTDLITTILPAFMPTAETQIFARFLKGFPAAVYYQGLLIMEEMTEEKHRAVLGNLYWLFWCVGYMFSGVVVYIFKEWDKIQLFSTVFCLNYIVIFIVVPESPRWLVLKGRVEEAVDVLKRIAKWNGIKWEHKVSKVKALDVEEEPTGNILDLVTYPEMRMKSIVIFSNLAMFAMCYFGLSTDTTFITTNIVLNVLLNGAVEIPSSFIGWLGSDRYGRKYTTVIITVL-SGFCLIAVPIVPTGGVYNIVKAVVAMVGKCLLTTGYCIADVWAAEIFPTSVRNNGLFLATTLAMLSNIVAPVINTLSDVATFLPGLIFGITSIVS-ALSLLLLPETKGLPLPETVPSSEGLVRGRERQWAIETFSR-ERAQSLLDDDDMEAVNSQRIIKQ 533
BLAST of slc22a-7 vs. TrEMBL
Match: A0A0H3YF32 (Slc22a-2 OS=Schmidtea mediterranea OX=79327 GN=slc22a-2 PE=2 SV=1) HSP 1 Score: 159.844 bits (403), Expect = 7.454e-39 Identity = 143/500 (28.60%), Postives = 243/500 (48.60%), Query Frame = 3
Query: 96 FKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQ-----ISKDQCT--MTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAY-HICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFR---MIFGSIGKVLVITSSQGVL-VYATELFPTTHRSLFFGMLQIILLMAMTAAVYINK-LNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSD 1553
F I+F+ LS+ F+Y +FQ L ++ P F+C S I+ ISKDQC +++N S KC WTF T++++ +LVCD + +L+ ++ L + F L+D G++++ I+ + + T+ T + + + G +S Y + Y L+E++ ++A + FW S L Y+ R+WR ++SL SI YVL FVPE+PRWL + ++ + +++ IA INK L WN K ++ FA ++ S DL S NI+I+ FV+GL+E P LS + RK+ ++ S G I + + + D +S+++ + ++G L +S+ + + EL PTT R+ ++ I + + A I+ L QFY P L+Y LL +I+ L+F F+PET LP+P+TI L+ +EQE+ M +++
Sbjct: 16 FHYISFMTLSITTFKYVVEFQGLTFALYEPKFSCLVKNISSTIRNSTNLISKDQCQYRLSVNDSWNKCDQWTFEKRFMRNTLINELNLVCDRAFYRELIFTTFFVGCLFSFPFSILSDSIGKRLLLIVSIFLSTIITIGQMVSYQIWQQLVLSFVSGVCKSVYVSLAYTTLIEIIPVSHIDLAATNFWNLYSFGYMSVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEAFKTMSFIAKINKCTLNKEEFNKWKPIQQVTGKFWNLLKHKTMIYRFLILNFAGWAFSFAYIGSATDLTFASENIFITTFVMGLVELPTGPLSGIMANKLGRKKSVSALSGLG-IICLIIMPFIEADSLKSVWQPWLKVCLAMGAKLGFSSAWLIFDIITNELIPTTDRNTAMSLVYITVGLGSIFAPMIHSVLLQFYFAGPFLLYSLLLLITVVLVFAFIPETHHLPVPQTIEQAVSLLIHKEQEWKMDMIQQAE 514
BLAST of slc22a-7 vs. Ensembl Cavefish
Match: slc22a4 (solute carrier family 22 member 4-like [Source:NCBI gene;Acc:103026746]) HSP 1 Score: 105.531 bits (262), Expect = 1.232e-23 Identity = 109/421 (25.89%), Postives = 197/421 (46.79%), Query Frame = 3
Query: 273 KC-QHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSFFWLYGS-VAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINKM---DLQLTPXXXXXXXXXXXS--NKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPG-----ALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLN--MISCCLIFVFMPETKGLPIPETI 1484
KC W +S E + TI++++DLVCD +Y L +++ LM + G L+DKYGR+ + ++++T+ FI F+P+ +GFS S Y + +V E+++ R V S GS + PL Y R WRL LI+ +LY+ L F+PESPRWL + + + L+ A NK+ ++ P EI+ ++ + + ++ N + + I++ ++++ + L + Y++ F+ ++E P LL Y S F + ++ + G I +F+ + + + M +GK + + V +ELFPT R++ G+ + + + +I L +Y +P Y LL + L+ + +PET G +PETI
Sbjct: 112 KCLDGWNYSKEIYQSTIVTEWDLVCDNEYKVPLCSSIYFLGVLMGTFISGQLSDKYGRRPVLFAMMAMQTLTIFIQMFSPSWEVFTAIYFFVGFSGFSNYVVGFVLGSEILSPATRVVFCSLGVFMGSGIGQMFLPLAAYFARWWRLLVLINALTGVLYIPLWWFIPESPRWLLSQGRIAEAEAILRQAAQKNKISAPEVIFIPSEIEESAAIRKKKYSILDILRNGNAVTICIICSLLWIVITMSYYGLILNTSNLHGDPYLNYFISAVVELPAFFIAMLLLKYCSRRFCQSSTLL----LGGGIILFVQLVPEDLPELAVFLEM----VGKFGITAAFCVVYAVTSELFPTVVRNMAMGICSMSARIGSIISPFIIYLGSYYKMLP---YLLLGAWAVVASLLCLLLPETSGKVLPETI 521
BLAST of slc22a-7 vs. Ensembl Cavefish
Match: ENSAMXT00000010878.2 (pep primary_assembly:Astyanax_mexicanus-2.0:14:29265439:29284025:-1 gene:ENSAMXG00000010589.2 transcript:ENSAMXT00000010878.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 105.531 bits (262), Expect = 1.534e-23 Identity = 109/434 (25.12%), Postives = 205/434 (47.24%), Query Frame = 3
Query: 273 KC-QHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF-GWLADKYGRKMISIIFLSIETVATFILAFTPNLS--SHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSF-FWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSN--KWNAFKDNNFLFLASTXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMF-GSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQ 1520
KC WT+S + + TI++++DLVCD ++ +++ L F G ++D++GRK + + ++T+ TFI F P+ S +FF + +G S Y +V E+++ R S L+ + + PL Y+ RNWR+ + P ++Y+ L F+PESPRWL + + + E+ + N + + L P+ I + +E N +NN L L TS ++ + + + ++ + L + Y++ F+ +E P + S+LS+ + RK + + G + F+ + + M GK + + + Y EL+PT R+ G ++ + A Y L+ ++ ++P ++ L + S L +F+PET P+PETI DQ +++RE+
Sbjct: 128 KCTDGWTYSKDVYQSTIVTEFDLVCDDEWKQPFTSSIYFIGVLCGSFFSGQISDRFGRKPVLFATMMVQTIFTFIQVFAPSWEVFSILFFIVGLG-QISNYVAAFVLGTELLSGGVRVFYSSLGVCLFFAFGYMMLPLIAYLIRNWRMLLVALSVPGLIYIPLWWFIPESPRWLISQGRVE---EAEAIVKNAARKNGVLPPDIIFKKSEEEEKNTKPQKTKPENNILDLMRTSNIRRTTLILFLVWLTLSMGYFGLSLNTSRLHGDSYVNCFISAALEVPAYITSWLSLRYLPRKLSCPVSMLLGGGVLYFIQLVPPDLPALSVALEM----AGKFGMAIGTALMFAYTGELYPTVLRNTAVGSCAMVSRVGSAVAPYFIHLSVYHKYLPYILLGTLCIFS-SLTTLFLPETFRRPLPETI-DQ---MQKRER 548
BLAST of slc22a-7 vs. Ensembl Cavefish
Match: SLC22A2 (solute carrier family 22 member 2-like [Source:NCBI gene;Acc:103036098]) HSP 1 Score: 103.99 bits (258), Expect = 4.147e-23 Identity = 122/509 (23.97%), Postives = 225/509 (44.20%), Query Frame = 3
Query: 147 SQFQNLLVSIQTPNFTCQ-YNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPV-FGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFS-ESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNN-------FLFLASTXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIIL-LMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLI 1610
SQ Q V + + C + + ++Q + T NG + +H ++ ++++DLVCD ++ D+ + L+ + G+LADK+GRKM ++ + V ++A +PN S + FR GF + + YV + E V G F ++ S + + L Y+ NWR Q+ P I+++ FVPESPRWL +NK + +E Q +A NK L S KD+N F+ L T + +++ +++ L +L NIYI + G++EFP A L ++ R+ ++ ++ + + W + IG++ + + + V+ TEL+PT R+L + + + + A + +L + +P++I+ +L ++ L+ + +PETKG+P+PETI D +EY N ++ED+ S ++ L+
Sbjct: 86 SQCQRYDVDWNSTDLNCDGLDSETTEVQRAGLPITACKNGWHYDYEH--------RESFVTEFDLVCDDAWLVDVFQAVLGIGFLVGSITIGYLADKFGRKMSFLLSNILNAVTGILVAISPNYISLVVFRALHGFGVKGGWMAAYVLMTETV--------GVLFQMFFSFGLLLLALIAYLIPNWRWLQVAFTVPYIIFLSYYWFVPESPRWLLSQNKSSRAVEVTQAMAKENKKTL---------------SQNIKNLKDDNAETSTGSFMDLIRTPKIRKHTLILSFNWFTSAVVYQGLIMRLGILRGNIYIDFLISGIVEFPAAFLILFTIERIGRRLPFAAANIVSGAACLITAFIPESVLW---LKTAVACIGRLGITMAFEMVVFVNTELYPTFIRNLGVSVCSTLCDIGGIIAPFLLYRLAVIWLELPLIIFGVLAFVAGGLV-LLLPETKGVPLPETIDD------------IEYP-------NRNKEDTMKSHQLENLL 540
BLAST of slc22a-7 vs. Ensembl Cavefish
Match: ENSAMXT00000046180.1 (solute carrier family 22 member 4-like [Source:NCBI gene;Acc:103029834]) HSP 1 Score: 100.138 bits (248), Expect = 6.835e-22 Identity = 70/276 (25.36%), Postives = 139/276 (50.36%), Query Frame = 3
Query: 60 ENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQ---YNETSHQIQISKDQCTM------TINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFR---NVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINKM 842
+ V SF F+V F++LSL G ++ TP++ C+ +N ++ ++ + C+ + NG+ + W +S+E + TI++++DLVC+ + + +++ L V G L+D++GRK++ ++I+T+++ I + + F G + S Y +V E++ K+ R +V G+ ++ ++ + PL Y+ R+WRL + P +LY+ L F+PESPRWL K + Q+ + ++ A N +
Sbjct: 7 DEVTSFLGDWGPFQVTIFILLSLSTVPNGYTGMAMVFLADTPSYRCRTSHWNGSAASLEHTWGTCSQVPALNGSSNGTGLCVDGWEYSTERYESTIVTEWDLVCENSWKVPFSLSIFFLGVLSGSFVSGELSDRFGRKVVLFATMAIQTLSSLIQVTSVSWEMFCVFFFLTGIGQISNYMAAFVLGCELLGKNLRVVYSVLGTC--VFYALGYALLPLCAYLLRSWRLLLTVLSLPGLLYIPLWWFIPESPRWLLAKGRVQEAEDIIRAAARRNGI 280
BLAST of slc22a-7 vs. Ensembl Cavefish
Match: zmp:0000001102 (solute carrier family 22 member 7-like [Source:NCBI gene;Acc:103028659]) HSP 1 Score: 99.3673 bits (246), Expect = 1.054e-21 Identity = 122/515 (23.69%), Postives = 223/515 (43.30%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQF--QNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSN------VKCQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF-GWLADKYGRKMISIIFLSIETVATFILA--FTPNLSSHIFFRLCIGFSESAYHICYV-----WLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF-VPESPRWLCVKNKKQQLMESLQTIANI-------NKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQ 1520
M EN+++ + +++ +L P F N + +I P+ C ++ + + Q + N SN V+CQ W F F T+ + +DLVCD K + ++++ + VF G ++DKYGR+ S++ LS T F +A F+ + FR GFS + I + W+ ++ ++ F V GS FW G++ + Y+ +WRL + +P +L + +PES RWL V + + LQ A++ +K+ L+ +++ ++ K L + + ++ I ++L N+Y++ F+ +E P Y S+ R+ + I IF+++ + K + W FR I +GK L S V +Y TEL+PT R G + + + + I L + +P +++ + ++S L+ + ET +PETI D + K R Q
Sbjct: 1 MKFENILTETDGFGRYQIAILALLVFPRMTLPGHFLLNNFIGAI--PSHHCDFS----SLDTYEAQFHLLTNTSNTTELPVVRCQDGWHFDHSTFKSTLATQFDLVCDTKGLNKASATIFFTGVMFGAVFFGVMSDKYGRR--SMLLLSYITSIVFSVASAFSTSFPMFATFRFLTGFSLAGISIISIVLSIEWV-DIEHRTFIGVIGSMFWTVGNMLLGGI---AYLVTDWRLLIITVTSPLLLAGATWWWIPESARWLIVNGRTDRAYSYLQKCASVNGKEEFTSKVKLETLSSVAEVDNHGHNYTYFDLIKTPRLRRLTLFTGIVWYGVASTYYGISLNLKGFGLNLYLTHFIYSAIEAPAKFFIYFSLQKIGRRPNQVGTLLLTGICIFINIVVPK-EYWT--FRTIIAVLGKGLSEASFTTVFLYTTELYPTVLRQNGLGYNSFVARLGASISPLIMLLEDVWRLLPQVVFGTMAIVS-GLVACLLQETNNTRLPETIED---IEKTRNQ 496
BLAST of slc22a-7 vs. Ensembl Sea Lamprey
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92]) HSP 1 Score: 98.5969 bits (244), Expect = 4.798e-22 Identity = 60/205 (29.27%), Postives = 109/205 (53.17%), Query Frame = 3
Query: 246 TMTINGSNVKCQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDL-LVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIG-FSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSI-LYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
++ +G + C H W F +E G T++S++DLVC+ ++ DL LL + A + G+++D+YGR+ ++ + ++T+ ++AF PN ++ + R G F+ ++ +V E V R V ++ S + + Y R WR QL P++ L+ +PESPRWL +N+K+Q L+ IA++N +L
Sbjct: 117 NVSFSGRLIACDHGWEFDTEKTGLTLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFGVIMLSGIAYYLRTWRYLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGREL 321 HSP 2 Score: 49.6766 bits (117), Expect = 1.573e-6 Identity = 42/183 (22.95%), Postives = 80/183 (43.72%), Query Frame = 3
Query: 1047 GLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIIL-LMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDR-EDSDAS 1589
GL E PGAL+ + R+ + + + + + W +I + G +G + + + V + EL+PT R++ + + + A + +L + +PM+I+ L +I + + +PET GLP+PET D + K ++ + + + N R EDS A
Sbjct: 393 GLAEIPGALMVIALIDRVGRRLPMCVAPGLSGLACLATALVPHDIGWLNITLVTLGRLGLTM---AYEMVTLVNNELYPTHLRNMAMSTCSSLSGIGGIVAPFVLYRLYTIWRHLPMVIFGTLAIIGG-FVILLLPETNGLPLPETTEDAENISKNQKMKQKMLRSRKFETKNPLRNEDSQAD 571
BLAST of slc22a-7 vs. Ensembl Sea Lamprey
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]) HSP 1 Score: 92.0485 bits (227), Expect = 9.350e-21 Identity = 60/199 (30.15%), Postives = 102/199 (51.26%), Query Frame = 3
Query: 270 VKC-QHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAP-VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESA-----YHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL---FVPESPRWLCVKNKKQQLMESLQTIANIN 836
V C W + F +T+++ +DLVC++K + L + L+ + ++ VFG+L+D+YGR+ + + V A+ P+ SS R +G S S + WL + ++ F +G F W G++A+ L Y+ R W+ QL+ +P +Y IL F+PESPRWL V+ + ++ +L A IN
Sbjct: 109 VPCPSGWEYDRRQFTETVVTQWDLVCEHKALNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWL-DQGHRTFAGTSGGFAWSTGNMALG---LLAYLLRGWQQLQLVVTSP--IYFCILTWWFIPESPRWLLVRGRAREAHRNLSLCARIN 301
BLAST of slc22a-7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007122.1 (pep scaffold:Pmarinus_7.0:GL476962:153150:164773:-1 gene:ENSPMAG00000006444.1 transcript:ENSPMAT00000007122.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.5514 bits (166), Expect = 2.763e-13 Identity = 52/186 (27.96%), Postives = 87/186 (46.77%), Query Frame = 3
Query: 204 NETSHQIQISKDQCTMTINGSNVK--CQHWTFSSEPFGKTIMSDYDLVCDYKY---VGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHI-CYVWLMEMVNKDFRNVAG-SFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYV 740
E++ + +C +N S + W + F T+++++DLVC Y VG + +L + APV G +ADKYGRK + ++ ++I+T AF PN + R +G + S + +V E R +AG + +G M + P+ Y R+WR QL P IL++
Sbjct: 70 GESAAANGTERPRCGSRLNESGWQPCATGWDYDRSVFTSTVVTEWDLVCTRSYLNNVGSSIFML--GLMVGAPVLGTMADKYGRKSVILVSMAIQTAFGLGAAFAPNFVMYALARFMVGVAISGVIMNAFVLATEWTGIGERMLAGIATQQAFGVGYMLLAPV-AYFIRDWRQLQLAISIPEILFI 252
BLAST of slc22a-7 vs. Ensembl Sea Lamprey
Match: si:dkey-190l8.2 (si:dkey-190l8.2 [Source:ZFIN;Acc:ZDB-GENE-030131-9103]) HSP 1 Score: 67.781 bits (164), Expect = 1.936e-12 Identity = 79/326 (24.23%), Postives = 144/326 (44.17%), Query Frame = 3
Query: 408 VFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWL-MEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF--VPESPRWLCVKNKKQQLMESLQTIANINKM-DLQLTPXXXXXXXXXXXSNKWN---AFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIF---LSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIIL-LMAMTAAV 1352
G +D+YGR+ + + ++ + A F++AF PN +++ RL G + S +C L +E R L SV M +++NW L + P ++ VL+LF +PESPRWL +K + + L+ + IN+ ++ TP + + +T+ +N+ F++ + ++S+ + + + +I+++ F+ GL E P LL L +R I S+ G+ + L L+ V + +GK+ ++ +Y ELFPT R G Q L +AM +V
Sbjct: 35 AMGIASDRYGRRPVLLGCVASQGAAEFVIAFLPNFPTYLLGRLLTGTTASGIMLCSFSLGVEWCGPALRAWPPIILALAFSVGMMALAGVAKISQNWPQLHLATGVPQLM-VLLLFWSLPESPRWLFLKKRTTEARNLLRQASIINRRSEVSWTPLRLTSKLSTRGANESTLLITFRNRTLRKRLLIMSYICAAVSMTYYGLCLSVGDFGLDIHMAQFLSGLAEIPQLLLPPLMRRVGRRSLCIVFLSVAGATCLLCLPLQPNLANVV-------VALALLGKLCAQVTACVATLYRIELFPTNVRPRCHGHRQNALGAVAMCGSV 352
BLAST of slc22a-7 vs. Ensembl Sea Lamprey
Match: svopl (SVOP-like [Source:NCBI gene;Acc:492766]) HSP 1 Score: 52.7582 bits (125), Expect = 1.468e-7 Identity = 40/149 (26.85%), Postives = 65/149 (43.62%), Query Frame = 3
Query: 414 GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVA---GSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPS-ILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDL 848
G+LAD+YGR + ++ + + I +F+P +F R +G +V + E + R FW+ GS+ V + T W IS PS +L + F+PES R+ K + + +L IA +NK L
Sbjct: 105 GFLADRYGRWKVLLLVTIWSSYWSGISSFSPTYGWFVFLRFLMGCGIGGQSQGFVLMSEFMPSTARGRVLPMSQVFWVLGSLLEVVLAYLILPTLGWAWLIRISTIPSFVLLIAFKFIPESARYQVSAAKPDKALLTLAKIAKMNKTTL 253
BLAST of slc22a-7 vs. Ensembl Yeast
Match: CIN10 (Putative transporter; member of the sugar porter family; non-essential gene; overexpression results in elevated colony sectoring, an indicator of chromosomal instability [Source:SGD;Acc:S000002795]) HSP 1 Score: 49.6766 bits (117), Expect = 9.077e-7 Identity = 44/143 (30.77%), Postives = 65/143 (45.45%), Query Frame = 3
Query: 420 LADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICY-VWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYV--------TRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQ 818
LAD+YGR++ I SI +A +A L+ I RL +G + C ++L E+ R F +A+T L YV +WR +S P+IL++ IL F+PESPRW K +SL+
Sbjct: 103 LADRYGRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRG----FMLTLNIIAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLR 241
BLAST of slc22a-7 vs. Ensembl Nematostella
Match: EDO36723 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW3]) HSP 1 Score: 119.398 bits (298), Expect = 8.995e-29 Identity = 116/439 (26.42%), Postives = 207/439 (47.15%), Query Frame = 3
Query: 201 YNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLL-VLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVA--TFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSI-LYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVL-GLMEFPGALLSYLSMYFFKRKRMITIFSMFGSI-FIFLSVTLSKVDKWQSIF-RMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQ 1493
Y+ ++ I++ +C + N ++ K P TI++ +DLVCD + L +L++ +L A + G +ADKYGR+ S++F S V TF ++F I R GF + +V E+V R ++ + W Y ++A+ V L Y ++W+L +IS P + +++ F+PES RWL V +K Q E L+ +A +NK ++ P+E K + + L L + + ++ L+ + FVL ++EFP +L + F RK + +++ G+I + +S S D I R+ G++GK+ + TS + V++ ELFPT R+ G+L +I + A ++ +L + +P + L ++ L F+PET+G P E + D
Sbjct: 69 YSTSTQPIELYHRRCKL--NRTDWKFADPELYEGPV-HTIVTQFDLVCDNSFHAWLANSMLFFGWALGAIILGMIADKYGRR--SVLFPSAACVIAITFSMSFAQASWVVIALRFFSGFFLGGSILTMFVLAAELVGPAKRALSSTMVWFYFTLALMVLGLQAYFIKDWKLLCIISTVPFVFIFIFWKFIPESVRWLLVVGRKDQAREILEQVAKVNKKEM---PKEDLRVPVVKHNRGFLELFGTPRLALLTLLQCYAWLVNGLVYYAVSMSAGDFGGSIYLNFVLTSIVEFPANILVIDNCNRFGRKHTVVWYTVVGAISCLVVSFIPSGTDNIGYIAGRVAAGTLGKLCITTSFNSLYVFSAELFPTMIRNSGMGLLSVISRVGAALAPFVVQLTRINAILPFALMSGLTFLA-ALACWFLPETRGKPTLEVMGDD 498
BLAST of slc22a-7 vs. Ensembl Nematostella
Match: EDO36696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW2]) HSP 1 Score: 110.538 bits (275), Expect = 7.151e-26 Identity = 116/451 (25.72%), Postives = 208/451 (46.12%), Query Frame = 3
Query: 201 YNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLL-VLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVA--TFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVL-GLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQS-----IFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQ 1520
Y+ ++ I++ +C + N ++ K P TI++++DLVCD+ + + +L++ ++ A G +ADKYGR S++F S V + +AF + R IGF E + +V E+V R +AG+ W+Y + A+ V L + R+W +IS+ P + VL FVPES RWL V K + L+ N+ +++ + PEE + + L + + + ++ ++ + FVL L+EFP +L + F RKR + +++ G+I +T+S + + I R+ G +GK+ + TS G+ V++ ELFPT R+ G+L +I + A ++ +L + +P + L ++ L F+PET+G P E I D + E +
Sbjct: 69 YSTSTQPIELYHRRCKL--NRTDWKFADPELYEGPV-HTIVTEFDLVCDHSFTAWMANSMLFFGWAIGAIFLGIIADKYGR--CSVLFPSAILVMGLSLAMAFVKKAWLVLVLRFFIGFFEGGGFLSMFVLATELVGPAKRALAGTLVWIYFTAALMVLALKAFFIRDWSTLCIISIAPFVFIVLFWKFVPESVRWLLVTGSKGKARRILE---NVARVNKKSMPEEELFAPQVEHNRGIIELFSTKRLAVLTLLQCYAWFVNGMVYYGVSMSAGDFGGSIYLNFVLTSLVEFPANVLLIHNCNRFGRKRTVVAYTLIGAI---ACITVSFIPAGTNNLGFIIGRVTGGMLGKLCITTSFNGLYVFSAELFPTMVRNSGMGLLSVISRVGAALAPFVVQLTRINAILPFALMGGLTFLA-ALACWFLPETRGKPTLEVIGDDDPHILEEGK 507
BLAST of slc22a-7 vs. Ensembl Nematostella
Match: EDO27829 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T865]) HSP 1 Score: 92.8189 bits (229), Expect = 7.660e-20 Identity = 107/442 (24.21%), Postives = 191/442 (43.21%), Query Frame = 3
Query: 279 QHWTFSSEPFGKTIMSDYDLVCD---YKYVGDLLV-LLWYSTSLMAPVFGWLADKYGRKMI---SIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIA-----NINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVIT------SSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYN 1544
W F+ + +I++++DLVC Y + + + +LW ++ + G DK+GRK++ +IF S+ +A+ AF FR +G Y IC +V +ME + R++ G W +A+ + L Y+ +WR +I+ P +L +V F P+S RW VK K + L +A N K D + E + + + + F + S + ++ I + + ++Y++ F+ L E G + + F RK+ I ++ ++ LS+ D M+ G I +VI + GV VY++ELFPT R+ G + AA + + + +P I LN + C ++ + +PETK P+P+T VK+ E+ EY +
Sbjct: 79 DQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIG---DKFGRKIVVFPCVIFASLCGLAS---AFANKYWVFALFRALLGAGIGGYSICGFVLVMEYIGIRHRSIVGFCVWYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLGDIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIVASMYVAALAAIVAALLSQYDDGSQ--AMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTVYSQKVHPMMPFGI-MALNALICGILCMTLPETKDKPLPDT-------VKQTEESPCEYAFE 504
BLAST of slc22a-7 vs. Ensembl Nematostella
Match: EDO36597 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI67]) HSP 1 Score: 92.0485 bits (227), Expect = 8.184e-20 Identity = 100/419 (23.87%), Postives = 186/419 (44.39%), Query Frame = 3
Query: 279 QHWTFSSEPFGKTIMSDYDLVCD---YKYVGDLLV-LLWYSTSLMAPVFGWLADKYGRKMI---SIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIA-----NINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGS--IGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFL--LNMISCCLIFVFMPETKGLPIPETI 1484
W F+ + +I++++DLVC Y + + + +LW ++ + G DK+GRK++ +IF S+ +A+ AF FR +G Y IC +V +ME + R++ G + +A+ + L Y+ +WR +I+ P +L+ + F P+S RW VK K + L +A N K D + E + + + + F + S + ++ I + + ++Y++ F+ L E G + + F RK+ I ++ ++ LS+ D + I + I K V + GV VY++ELFPT R+ G + AA + K++ PM+ + + LN + C ++ + +PETK P+P+T+
Sbjct: 79 DQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIG---DKFGRKIVVFPCVIFASLCGLAS---AFANKYWVFALFRALLGAGIGGYSICSFVLVMEYIGIRHRSIVGFCVFYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLGDIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIAASMCVAALAAIVAALLSQYDDGTMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTQKVH------PMMPFGIMALNALICGILCMTLPETKDKPLPDTV 485
BLAST of slc22a-7 vs. Ensembl Nematostella
Match: EDO47316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMR6]) HSP 1 Score: 90.5077 bits (223), Expect = 2.247e-19 Identity = 101/420 (24.05%), Postives = 187/420 (44.52%), Query Frame = 3
Query: 279 QHWTFSSEPFGKTIMSDYDLVCD---YKYVGDLLV-LLWYSTSLMAPVFGWLADKYGRKMI---SIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHIC-YVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSIL-YVLILFVPESPRWLCVKNKKQQLMESLQTIA-----NINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGS--IGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFL--LNMISCCLIFVFMPETKGLPIPETI 1484
W F+ + +I++++DLVC Y + + + +LW ++ + ++DK+GRK++ +IF S+ +A+ AF FR +G Y IC +V +ME + R++ G W +A+ + L Y+ +WR +I+ P +L +V F P+S RW VK K + L +A N K D + E + + + + F + S + ++ I + + ++Y++ F+ L E G + + F RK+ I ++ ++ LS+ D + I + I K V + GV VY++ELFPT R+ G + AA + K++ PM+ + + LN + C ++ + +PETK P+P+T+
Sbjct: 79 DQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSI---ISDKFGRKIVVFPCVIFASLCGLAS---AFANKYWVFALFRALLGAGIGGYSICGFVLVMEYIGIRHRSIVGFCVWYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLGDIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIVASMYVAALAAIVAALLSQYDDGTMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTQKVH------PMMPFGIMALNALICGILCMTLPETKDKPLPDTV 486
BLAST of slc22a-7 vs. Ensembl Medaka
Match: slc22a4 (solute carrier family 22 member 4 [Source:NCBI gene;Acc:101163192]) HSP 1 Score: 111.694 bits (278), Expect = 1.130e-25 Identity = 120/429 (27.97%), Postives = 202/429 (47.09%), Query Frame = 3
Query: 276 CQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF-GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSFFWLYGS-VAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF--VPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAF------KDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD-QRLLVKEREQE 1523
CQ W +S E + TI++++DLVCD Y G L + Y L+ V G L+D++GRK + + ++++TVA F+PN F +G S Y I +V E+++ R V S GS V P Y R+WR + LIS+ S L + L+ + ESPRWL + K ++ L+ A +NK+ + P + E + K K N L + I+I A+L++ + L+ N Y++ F+ + E P +++ L + + R + G + I L V L +D ++ +GK V + V +ELFPT R+ G + +A + +I L ++Y +P ++ +L + + F+ +PET+G +PETI QR+ K+ E+E
Sbjct: 118 CQDGWIYSREIYQSTIVTEWDLVCDNAYKGPLTTSIHYVGVLVGTVLSGQLSDRFGRKPMLFVMMALQTVAITAQIFSPNWEIFTFIFCLVGAGGYSNYTIAFVLGSEILSPRIRVVFCSLGVFMGSAVGYMAMPAVAYFLRDWR-SLLISMAASGLIYIPLWWLLSESPRWLLSQGKVEEAEAILKDAAKMNKVQVP-EPIFTQAEVEDSLAMKERKINIMVIVKSCNILSITMACASLWMIITISYYALLLNTSNLNGNPYLNCFLSAVTEVPAYIIALLLLRYCSRHICQSSTLFLGGVMI-LCVRLIPID--LPAVAVLLEMLGKFGVTAAFCVVYSVTSELFPTVIRNTAMGCCSMAARIATILSPFIIYLGKYYKALPYIVMGVLALSGAVITFI-LPETRGKVLPETIPQMQRICGKQGEKE 540
BLAST of slc22a-7 vs. Ensembl Medaka
Match: slc22a2 (solute carrier family 22 member 2 [Source:NCBI gene;Acc:101173762]) HSP 1 Score: 105.916 bits (263), Expect = 1.045e-23 Identity = 59/190 (31.05%), Postives = 106/190 (55.79%), Query Frame = 3
Query: 279 QHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPV-FGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFS-ESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYV-LILFVPESPRWLCVKNKKQQLMESLQTIANINK 839
+ W + E ++ ++++DLVC + ++ D+ L+ + G+LAD++GRKM ++ + VA ++A +PN +S + FR GF + + YV + E+V +FR G + ++ SV + + PL + +WR QL P IL++ F+PESPRWL +NKK Q+++ ++IA N+
Sbjct: 119 EGWEYDYEGR-QSFVTEFDLVCSHGWMADMFQATLNVGFLVGSIAIGYLADRFGRKMSFLMSTLVNAVAGILVAVSPNYTSLLVFRSLSGFGVKGGWMAGYVLITEIVGVEFRRTVGVLYQMFFSVGLLILPLLAFFITDWRWLQLAITAPYILFLSYYWFIPESPRWLLSQNKKSQVVKITESIAKENR 307
BLAST of slc22a-7 vs. Ensembl Medaka
Match: slc22a4 (solute carrier family 22 member 4 [Source:NCBI gene;Acc:101163192]) HSP 1 Score: 105.916 bits (263), Expect = 1.049e-23 Identity = 117/431 (27.15%), Postives = 198/431 (45.94%), Query Frame = 3
Query: 276 CQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVF-GWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSE-SAYHICYVWLMEMVNKDFRNVAGSFFWLYGS-VAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILF--VPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAF------KDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLE 1532
CQ W +S E + TI++++DLVCD Y G L + Y L+ V G L+D++GRK + + ++++TVA F+PN F +G S Y I +V E+++ R V S GS V P Y R+WR + LIS+ S L + L+ + ESPRWL + K ++ L+ A +NK+ + P + E + K K N L + I+I A+L++ + L+ N Y++ F+ + E P +++ L + + R + G + I L V L +D ++ +GK V + V +ELFPT R+ G + +A + +I L ++Y +P ++ +L + + F+ +PET+G +PETI + + E E
Sbjct: 118 CQDGWIYSREIYQSTIVTEWDLVCDNAYKGPLTTSIHYVGVLVGTVLSGQLSDRFGRKPMLFVMMALQTVAITAQIFSPNWEIFTFIFCLVGAGGYSNYTIAFVLGSEILSPRIRVVFCSLGVFMGSAVGYMAMPAVAYFLRDWR-SLLISMAASGLIYIPLWWLLSESPRWLLSQGKVEEAEAILKDAAKMNKVQVP-EPIFTQAEVEDSLAMKERKINIMVIVKSCNILSITMACASLWMIITISYYALLLNTSNLNGNPYLNCFLSAVTEVPAYIIALLLLRYCSRHICQSSTLFLGGVMI-LCVRLIPID--LPAVAVLLEMLGKFGVTAAFCVVYSVTSELFPTVIRNTAMGCCSMAARIATILSPFIIYLGKYYKALPYIVMGVLALSGAVITFI-LPETRGKVLPETIPQMQRICGNANCEASE 542
BLAST of slc22a-7 vs. Ensembl Medaka
Match: ENSORLT00000024218.2 (solute carrier family 22 member 7 [Source:NCBI gene;Acc:101170147]) HSP 1 Score: 101.679 bits (252), Expect = 1.768e-22 Identity = 118/473 (24.95%), Postives = 212/473 (44.82%), Query Frame = 3
Query: 135 FQYGSQFQNLLVSIQTPNFTCQYNETSHQIQI-SKDQCTMTINGSN------VKCQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWY-STSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWL-MEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL--FVPESPRWLCVKNKKQQLMESLQTIANINKMD---LQLTPXXXXXXXXXXXSNKWNAFKD----NNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFS--MFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFD 1490
F+ S+ + L+VSI Q + +SH Q+ ++ Q + NG+N + C + W + + F T+ S +DLVCD K + +++ L A +FG+L+D++GRK ++ T F AF+ N + R G S I + L +E V+ R G L S + V P Y +WR + ++T +L +I ++PES RWL K + L A +N + L PE + ++ N+ ++ D LA + F ++ I +++ NIY++ F+ G+ E P +++ + K R +T + + IF ++ + + Q R G++GK+L + V +Y TEL+PT R G + + ++ + + L + + +P I+ + I+ L F+PET+ + +PETI D
Sbjct: 60 FRNLSELEKLVVSIP-----AQQDGSSHSCQMFAEPQYHLVWNGTNSTDPLKIPCTNGWWYDNTTFKSTLASQWDLVCDKKSMNRATATIFFMGVMLGAAIFGYLSDRFGRKRTLLVSYIATTTFGFASAFSYNFPMFVAMRFLTGVGISGISIVSIVLCVEWVDIKHRTYVGVLMSLDWSFSTVVLPALAYFVNDWR-SLTATVTAPLLAAMITWRWLPESARWLISTGKVDRAHFYLHQCATVNHREDFMADLKPEVLSKVILVEDENRKYSYVDLVKTPRMRRLALLTGIVWFGVACTYYGISLNVTGFGVNIYLTQFIYGVTEVPAK--AFIVFFLNKIGRRLTQVGTLLLTGLCIFCNIFIPQD---QVAARTTVGALGKMLAEAAFTTVFLYTTELYPTVMRQNGLGYSSFMARIGVSVSPLMMILEETWIHLPNTIFSAVAFIA-GLSASFLPETRNIRLPETIED 520
BLAST of slc22a-7 vs. Ensembl Medaka
Match: ENSORLT00000042842.1 (solute carrier family 22 member 7 [Source:NCBI gene;Acc:101172381]) HSP 1 Score: 93.9745 bits (232), Expect = 5.650e-20 Identity = 103/438 (23.52%), Postives = 195/438 (44.52%), Query Frame = 3
Query: 270 VKCQH-WTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLM-APVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWL-MEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLI-LFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNK-------WNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKE--REQEYLEYMYN 1544
VKCQ+ W + F T+ +++DLVC+ K++ +++ + AP+FG+L+D++GR+ + ++ + A + + R G S + I + L +E + R +G L ++ + Y WR L + +P IL V++ ++PES RWL K + + A +NK LT + + ES + + FK N LA + F ++ I ++++ N +++ F+ +E P + Y S+ R+R + S+ +F+++ +SK +KW + R I G +GK S + +Y TEL+PT R G + + ++ + + + + +P IY + + S +I +PET +PE I D K+ R +E M++
Sbjct: 107 VKCQNGWVYDKSIFRSTLATEWDLVCNKKWMNKATATVFFIGVMTGAPLFGYLSDRFGRRPLLLVSYLSSLTFAILSAVSTSFVMFAIMRFLTGISLAGISIISIALNIEWCSTKHRTFSGIIISLDWTLGNWLLVGIAYGINEWRTLILAATSPLILAVMVWRWLPESARWLIANGKAEAAQYYMMKCAKMNKGSKGLTTIIPEALLESVESEREGKKFTVADLFKTPNMRKLAICTGIVWFGVAFTYYGITLNISGFGLNPHLTQFIFASIEMPMKIAVYFSLEKLGRRRCEVTALLATSLLLFINIFVSK-EKW--LIRTIVGVLGKSTSEASFTIMYLYTTELYPTVVRQNGLGYTAFLARLGVSVSPLVVLSEEAWHLLPACIYCAVALGS-GVIASLLPETLDAQLPEFIEDIEKTRKQSVRREEIQSNMHD 540
BLAST of slc22a-7 vs. Planmine SMEST
Match: SMESG000025785.1 (SMESG000025785.1) HSP 1 Score: 970.304 bits (2507), Expect = 0.000e+0 Identity = 519/525 (98.86%), Postives = 522/525 (99.43%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRKFR 1625
MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSI+TPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFG+TIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNL SHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKE NKWNAFKD NFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLV+TSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRKFR
Sbjct: 1 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIRTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGETIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLYSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKEWNKWNAFKDMNFLFLASTSLFAVFSISILISAILIDLNLLSSNIYISMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVMTSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSDASSEMSQLINRKFR 525
BLAST of slc22a-7 vs. Planmine SMEST
Match: SMESG000025822.1 (SMESG000025822.1) HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0 Identity = 270/528 (51.14%), Postives = 381/528 (72.16%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDV-VNSDRE----DSDASSEMSQLINRK 1619
MILE+++ YNK++TFK +AF ILSLP+FQ+ SQ QN+L+S TP +TC YN + +I IS DQC M I+GS + C W FS EP G+T+MSD+ LVC+YK +GD+++++WYSTS+ P+ GW +DK+GRK ++I L +ET++TF ++FTP+++S+I RL IG S + ++ CYVWLMEMV+ +FR +GSF W YG +A VFPLT Y T++WR+TQLISL P+ILY LIL PESPRWLCV N+K +L++SL IA INK+D + E+I + KT E N W A KD F + S VFSI+++ +AI ++L +LS+N+YISMF+LGLMEFPG L SY+S+ FF+RK + GSIFI +SV S+ WQ + R+IFG I K+ V T +Q +VY +EL PT+HRSL F +Q+ L + TAA+YINKL+ F+PM+IYF+L ++ C+I++++PETK LPIPET+ DQ++L +E+E+L+YM + ++ V SD + S+ S+E S LINRK
Sbjct: 1 MILEDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTCLYNSSFSKISISADQCNMIIDGSTIVCNKWNFSYEPVGRTMMSDFSLVCNYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILFSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAIYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREMEVESDLDLDLLKSNESTEESHLINRK 528
BLAST of slc22a-7 vs. Planmine SMEST
Match: SMESG000025819.1 (SMESG000025819.1) HSP 1 Score: 523.857 bits (1348), Expect = 0.000e+0 Identity = 270/528 (51.14%), Postives = 380/528 (71.97%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDV-VNSDRE----DSDASSEMSQLINRK 1619
MILE+++ YNK++TFK +AF ILSLP+FQ+ SQ QN+L+S TP +TC YN + +I IS DQC M I+GS + C W F EP G+T+MSD+ LVCDYK +GD+++++WYSTS+ P+ GW +DK+GRK ++I L +ET++TF ++FTP+++S+I RL IG S + ++ CYVWLMEMV+ +FR +GSF W YG +A VFPLT Y T++WR+TQLISL P+ILY LIL PESPRWLCV N+K +L++SL IA INK+D + E+I + KT E N W A KD F + S VFSI+++ +AI ++L +LS+N+YISMF+LGLMEFPG L SY+S+ FF+RK + GSIFI +SV S+ WQ + R+IFG I K+ V T +Q +VY +EL PT+HRSL F +Q+ L + TAA+YINKL+ F+PM+IYF+L ++ C+I++++PETK LPIPET+ DQ++L +E+E+L+YM + ++ V SD + S+ S+E S LINRK
Sbjct: 1 MILEDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTCLYNSSFSKISISADQCNMIIDGSTIVCNKWNFLYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEINKIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVFSINLIYAAIAVNLQILSNNMYISMFLLGLMEFPGILFSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRSLGFASIQLANLCSFTAAIYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREMEVESDLDLDLLKSNESTEESHLINRK 528
BLAST of slc22a-7 vs. Planmine SMEST
Match: SMESG000025834.1 (SMESG000025834.1) HSP 1 Score: 326.25 bits (835), Expect = 1.243e-105 Identity = 202/528 (38.26%), Postives = 321/528 (60.80%), Query Frame = 3
Query: 51 MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQISKDQCTMTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVITSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSD-----VVNSDREDSDASSEMSQLINRK 1619
M L+N++S NK TFK++AF ILSLP FQ SQ QN+L ++ PNF C++N S I +SKDQC++ +NG+ + C+ W FS P G T++SD+ LVCD +Y+GD+++++WY+ L+ P+ G+++D++GRK I I+ L +ET ++ +LA +PN ++++ FR+ +G S + S L S+ LT + Y+ I F+PESPRWLCV N+K ++MESL+ ++ IN++ + ++I +E KE N A KD +F + T+LF FSI+++ S++L+D+ +LSSN+Y+S+F+LGLME P LLSY + + KRK + GS+ +F+S+ SK QS+ R++ G + K+ + + +Q ++VY ELFPTTHRS +L I ++ + AV IN+L+ F+P LIYF I +++ +PETK LPIPET+ D ++L +E+E++ YM N+ V NSD + S+ +E S+LI K
Sbjct: 1 MFLDNILSDINKPLTFKIVAFFILSLPTFQSCSQIQNILFALFIPNFKCKFNSKSKFI-VSKDQCSILMNGTTMNCKEWDFSLLPIGSTLVSDFGLVCDNRYLGDVILMVWYAMFLLGPLVGFMSDRFGRKNIVILSLVLETFSSILLALSPNFATYLTFRILLGLSA--------------------ILSSGRLLDRSIGSIGQSLTC-----------------VFYLFIFFMPESPRWLCVMNRKDEMMESLRFMSKINRLRFDVEKDQIYVENLVKEGNICVACKDTDFQSRSITALFCAFSINLIYSSMLVDIGILSSNMYLSVFLLGLMELPSLLLSYYVLRYIKRKIGFLLIGGVGSLLLFISIFFSKSIPLQSVIRIVLGCLSKIAISSCNQNIMVYVNELFPTTHRSFGITLLLISNFLSFSGAVLINRLSVISYFLPTLIYFSFLWIVGVVVYFSLPETKDLPIPETLIDMKMLKCGKEEEFVFYMQNKHKYFNHTVDNSDEKSSENLNEKSKLITGK 490
BLAST of slc22a-7 vs. Planmine SMEST
Match: SMESG000004219.1 (SMESG000004219.1) HSP 1 Score: 160.614 bits (405), Expect = 1.058e-42 Identity = 144/510 (28.24%), Postives = 247/510 (48.43%), Query Frame = 3
Query: 96 FKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQYNETSHQIQ-----ISKDQCT--MTINGSNVKCQHWTFSSEPFGKTIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSIETVATFILAFTPNLSSHIFFRLCIGFSESAY-HICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLIL-FVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPXXXXXXXXXXXSNKWNAFKDNNFLFLASTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMFVLGLMEFPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFR---MIFGSIGKVLVITSSQGVL-VYATELFPTTHRSLFFGMLQIILLMAMTAAVYINK-LNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDREDSD 1583
F I+F+ LS+ F+Y +FQ L ++ P F+C S I+ ISKDQC +++N S KC WTF T++++ +LVCD + +L+ ++ L + F L+D G++++ I+ + + T+ T + + + G +S Y + Y L+E++ ++A + FW S + L Y+ R+WR ++SL SI YVL FVPE+PRWL + ++ + +++ IA INK L WN K ++ FA ++ S DL S NI+I+ FV+GL+E P LS + RK+ ++ S G I + + + D +S+++ + ++G L +S+ + + EL PTT R+ ++ I + + A I+ L QFY P L+Y LL +I+ L+F F+PET LP+P+TI L+ +EQE+ M +++ + S+
Sbjct: 16 FHYISFMTLSITTFKYVVEFQGLTFALYEPKFSCLVKNISSTIRNSTNLISKDQCQYRLSVNDSWNKCDQWTFEKRFMRNTLINELNLVCDRAFYRELIFTTFFVGCLFSFPFSILSDSIGKRLLLIVSIFLSTIITIGQMVSYQIWQQLVLSFVSGVCKSVYVSLAYTTLIEIIPVSHIDLAATNFWNLYSFGYMLVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEAFKTMSFIAKINKCTLNKEEFNKWKPIQQVTGKFWNLLKHKTMIYRFLILNFAGWAFSFAYIGSATDLTFASENIFITTFVMGLIELPTGPLSGIMANKLGRKKSVSALSGLG-IICLIIMPFIEADSLKSVWQPWLKVCLAMGAKLGFSSAWLIFDIITNELIPTTDRNTAMSLVYITVGLGSIFAPMIHSVLLQFYFAGPFLLYSLLLLITVVLVFAFIPETHHLPVPQTIEQAVSLLIHKEQEWKMDMIQQAEKLGMVHRPSE 524 The following BLAST results are available for this feature:
BLAST of slc22a-7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc22a-7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc22a-7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of slc22a-7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc22a-7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc22a-7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30011820 ID=SMED30011820|Name=slc22a-7|organism=Schmidtea mediterranea sexual|type=transcript|length=1666bpback to top protein sequence of SMED30011820-orf-1 >SMED30011820-orf-1 ID=SMED30011820-orf-1|Name=SMED30011820-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=526bp MILENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIQTPNFTCQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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