Transmembrane emp24 domain-containing protein eca

Overview
NameTransmembrane emp24 domain-containing protein eca
Smed IDSMED30011806
Length (bp)774
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transmembrane emp24 domain-containing protein eca (SMED30011806) t-SNE clustered cells

Violin plots show distribution of expression levels for Transmembrane emp24 domain-containing protein eca (SMED30011806) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transmembrane emp24 domain-containing protein eca (SMED30011806) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transmembrane emp24 domain-containing protein eca (SMED30011806) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30011806

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30011806h1SMcG0013789 SmedASXL_004488SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30011806h1SMcG0013789 SmedASXL_004488SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30011806h1SMcG0013789 dd_Smed_v6_9884_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30011806h1SMcG0013790 OX_Smed_1.0.01614ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
head regionSMED30011806h1SMcG0013789 OX_Smed_1.0.01614ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Human
Match: TMED9 (transmembrane p24 trafficking protein 9 [Source:HGNC Symbol;Acc:HGNC:24878])

HSP 1 Score: 150.214 bits (378), Expect = 4.092e-44
Identity = 70/214 (32.71%), Postives = 130/214 (60.75%), Query Frame = 1
Query:  112 LIENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++  + ++L +     +++F++ E EKKCF+E++ D  +  G Y+ + YD  ++ Y   +   G+ V V D +  +I+++ Y  EG F+FT+H  GE ++C+ + S   +      LR++LD +  E A+DY +   +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +G WQ+ +LK+FF +KKL
Sbjct:   21 VMRTLLLVLWLATRGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKL 234          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 143.665 bits (361), Expect = 1.113e-41
Identity = 67/200 (33.50%), Postives = 123/200 (61.50%), Query Frame = 1
Query:  154 VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
               ++F++ E EK+CF+E++ D  +  G Y+ + +D  ++ ++  +   G+HV V D DG +++S+ Y  EG F+FT+H  G+ ++C+  ++  +A     KLR++LD +  E A++Y +   +  L + + + + ++  +  I  +Q+YQR +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:   27 AQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKL 226          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 95.1301 bits (235), Expect = 1.910e-23
Identity = 54/198 (27.27%), Postives = 94/198 (47.47%), Query Frame = 1
Query:  154 VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
               ++F++ E EK+CF+E++ D  +  G Y+ + +D  ++ ++  +   G+HV V D DG +++S+ Y  EG F+FT+H  G+ ++C+ + S         ++Y                                               +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:   27 AQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLY-----------------------------------------------REERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKL 177          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 89.7373 bits (221), Expect = 2.512e-21
Identity = 43/152 (28.29%), Postives = 90/152 (59.21%), Query Frame = 1
Query:  154 VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQR 603
               ++F++ E EK+CF+E++ D  +  G Y+ + +D  ++ ++  +   G+HV V D DG +++S+ Y  EG F+FT+H  G+ ++C+  ++  +A     KLR++LD +  E A++Y +   +  L + + + + ++  +  I  +Q+YQR
Sbjct:   27 AQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQR 178          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Human
Match: TMED10 (transmembrane p24 trafficking protein 10 [Source:HGNC Symbol;Acc:HGNC:16998])

HSP 1 Score: 73.9442 bits (180), Expect = 2.768e-15
Identity = 53/198 (26.77%), Postives = 100/198 (50.51%), Query Frame = 1
Query:  154 VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            V +I F++    +KC  E++  +++  G Y+I   D +  A   +S     H+ + D  G I+ SK    +G F+FTT  +  F+VC  +     I      + LD +    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN+R+L++S    F L+ +  WQ+  L+ FF +KKL
Sbjct:   29 VLAISFHLPINSRKCLREEIHKDLLVTGAYEIS--DQSGGAGGLRS-----HLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQ--LVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKL 217          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Celegans
Match: Y60A3A.9 (pep chromosome:WBcel235:V:19946691:19949093:-1 gene:WBGene00013360.1 transcript:Y60A3A.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y60A3A.9)

HSP 1 Score: 163.31 bits (412), Expect = 6.045e-50
Identity = 81/205 (39.51%), Postives = 126/205 (61.46%), Query Frame = 1
Query:  133 LLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            LL +  Y  S++F++ E EKKCF+E++ D  +  G YK++ YD N K Y     + G+HV V D +  +I+SK YT EG F+FT++  GE  +CI + S AW    +LR++LD +  + A DY     +  L++ + +I+ ++  +  I  +QNYQR +EE+FR+T   TNSR+ +WS  Q  VL   G WQ+ +L+ FF +KKL
Sbjct:    7 LLSLATYADSLYFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGY-GDYPNIGMHVEVKDPEDKVILSKLYTAEGRFTFTSNTPGEHVICIYSNSTAWFNGAQLRVHLDIQAGDHAQDYAQIAQKDKLNELQLRIRQLLDQVDQITKEQNYQRYREERFRQTSESTNSRVFYWSIAQVVVLAITGAWQMRHLRGFFEAKKL 210          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Celegans
Match: T08D2.1 (pep chromosome:WBcel235:X:162529:163134:-1 gene:WBGene00011606.1 transcript:T08D2.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08D2.1)

HSP 1 Score: 101.679 bits (252), Expect = 1.335e-26
Identity = 52/138 (37.68%), Postives = 83/138 (60.14%), Query Frame = 1
Query:  133 LLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAK 546
            LL +  Y  S++F++ E EKKCF+E++ D  +  G YK++ YD N K Y     + G+HV V D +  +I+SK YT EG F+FT++  GE  +CI + + AW    +LR++LD +  + A DY      + LD+++ K
Sbjct:    7 LLSLATYADSLYFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGY-GDYPNIGMHVEVKDPEDKVILSKLYTSEGRFTFTSNTPGEHVICIYSNTTAWFNGAQLRVHLDIQAGDHAQDYAQVEEERKLDENREK 143          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Celegans
Match: F47G9.1 (pep chromosome:WBcel235:V:11323965:11326964:-1 gene:WBGene00009829.1 transcript:F47G9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F47G9.1)

HSP 1 Score: 80.4925 bits (197), Expect = 3.003e-18
Identity = 56/213 (26.29%), Postives = 96/213 (45.07%), Query Frame = 1
Query:  115 IENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKLFN 753
            ++++ I L  I   HS+ FY+   EKKC  E++  N++  G Y  E+    Q           +HV    G            +G F+FT  ++  F++CI     A     K  + L  +    A +Y D    + L   + +++ +  +  +I     + R +EE+ R T   TNSR+L+ S      LL +  WQ++ L+ +F SKKL +
Sbjct:    1 MKSLVIFLSAIVLAHSLRFYVPPKEKKCLKEEIHKNVVVTGEY--EFSQGIQYT-------GSIHVTDTRGHTLYKRENFADLKGKFAFTADEYDIFEICIENHPPAGHPGEKREVSLILKHGVEAKNYDDIAKAEKLKPLEVELRRLEDMADSITKDFAFMRQREEEMRNTNESTNSRVLYLSIFSMLCLLGLAIWQVLFLRNYFKSKKLID 204          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Fly
Match: eca (gene:FBgn0069242 transcript:FBtr0082098)

HSP 1 Score: 173.326 bits (438), Expect = 1.301e-53
Identity = 80/209 (38.28%), Postives = 132/209 (63.16%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++ ++LC+++    ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  I++S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY     ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFWQ+ +LK+FF +KKL
Sbjct:    7 SLALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Fly
Match: p24-2 (gene:FBgn0053105 transcript:FBtr0082093)

HSP 1 Score: 160.229 bits (404), Expect = 4.200e-48
Identity = 75/206 (36.41%), Postives = 126/206 (61.17%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHS 738
            ++ ++LC+++    ++F++++ E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  I++S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY     ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFW + NL   FH+
Sbjct:    7 SLALILCVLHSACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNL---FHT 209          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Fly
Match: p24-2 (gene:FBgn0053105 transcript:FBtr0303038)

HSP 1 Score: 160.229 bits (404), Expect = 4.200e-48
Identity = 75/206 (36.41%), Postives = 126/206 (61.17%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHS 738
            ++ ++LC+++    ++F++++ E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  I++S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY     ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFW + NL   FH+
Sbjct:    7 SLALILCVLHSACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNL---FHT 209          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Fly
Match: bai (gene:FBgn0045866 transcript:FBtr0084758)

HSP 1 Score: 62.3882 bits (150), Expect = 1.946e-11
Identity = 50/203 (24.63%), Postives = 90/203 (44.33%), Query Frame = 1
Query:  157 HSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVC-ISTVSV---AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKLFN 753
            H++ F ++   +KC  ED+Q N +  G +++         Y+ + T    H++           K +  +G FSF +  +  +++C IS V       I+ V L      ET      Y        L   +  +K +  +  +I+      R +EE+ R+T   TNSR+L++S      LL +  WQ++ L+ +F +KKL  
Sbjct:   19 HAVMFKLSPNTQKCLKEDIQANQLVMGEFEVSDVPGQIIDYIARDTKG--HIL---------SQKEHITKGKFSFMSEVYDTYEICFISKVPAHQRGVIQEVSLLTKKGVETK----SYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Fly
Match: p24-1 (gene:FBgn0030341 transcript:FBtr0073604)

HSP 1 Score: 48.9062 bits (115), Expect = 9.848e-7
Identity = 31/128 (24.22%), Postives = 60/128 (46.88%), Query Frame = 1
Query:  376 SFTTHKF-----GEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKK 744
            +F +H+F     G +  C      A+   +   +Y+DF+  E         +   L Q +   +AI   + +IL  Q + R++E + R+     N R++ WS ++   ++ +G  QI+ L+ FF  +K
Sbjct:   77 TFDSHQFVAETTGVYTACFGNQFSAFSHKI---VYVDFQVGEEPALPGVDEHATVLTQMETSSQAIHKGLNDILDAQTHHRLREAQGRKRAEDLNQRVMVWSSLETAAVIVIGLVQIMVLRNFFTDRK 201          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Zebrafish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:ZFIN;Acc:ZDB-GENE-050417-434])

HSP 1 Score: 149.443 bits (376), Expect = 4.304e-44
Identity = 76/209 (36.36%), Postives = 129/209 (61.72%), Query Frame = 1
Query:  130 ILLCIIN-YVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +LL I N  V +++F++ E EKKCF+E++ D  +  G Y+ + YD  ++ Y+  +   G+ V V D D  +I+S+ Y  EG F FT+H  GE ++C+ + S   A      LR++LD +  E  ++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +GFWQ+ +LK+FF +KKL
Sbjct:   14 VLLNIYNSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFIFTSHTPGEHQICLHSNSSKFALFAGGMLRVHLDIQVGEHTNNYAEIAAKDKLTELQLRVRQLMEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKL 222          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Zebrafish
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:ZFIN;Acc:ZDB-GENE-040625-140])

HSP 1 Score: 145.591 bits (366), Expect = 1.638e-42
Identity = 67/208 (32.21%), Postives = 126/208 (60.58%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +L   ++   +++F++ E EKKCF+E++ D  +  G Y+ + +D    +++  +   G+HV + D +  +I+S+ Y  +G F+FT+H  GE ++C+  ++  +A     KLR++LD +  E  ++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:   17 LLFVWLSPSQALYFHIGETEKKCFIEEIPDETMVIGRYRTQLWDKQAGSFLPSTPGLGMHVEIKDPETKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTVILIITGIWQMKHLKSFFEAKKL 224          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Zebrafish
Match: si:ch211-255i20.3 (si:ch211-255i20.3 [Source:ZFIN;Acc:ZDB-GENE-141216-113])

HSP 1 Score: 114.775 bits (286), Expect = 8.534e-31
Identity = 65/208 (31.25%), Postives = 116/208 (55.77%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAW--IETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +L   +    +++F + E E+KC +E++  + +  G +++EY+D N+K+    +   GL V V D   ++++ K +   G F+FT+   G+  +C+ + S  +      +L+++LD +  E   D      +  +   +  ++ +I  MR I  QQ++QR +EEKFR+    TN  +LWW+ +Q  +LL VGFWQ+ NLK FF  KKL
Sbjct:   15 LLASFVILASAMYFDLGEQEEKCIIEEIPVDTLVTGVFRLEYWDENKKS---NTPQLGLTVTVRDPQHEVVLLKRFGRYGKFTFTSPASGQHFLCMQSNSTRFSVFAGDRLKVHLDVQMGEHTIDPNAAKTKDTIKAMEYNLQHLIDQMRYISRQQDFQREREEKFRQMSEETNGNVLWWAIIQTSILLSVGFWQMKNLKDFFIEKKL 219          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 77.0258 bits (188), Expect = 1.143e-16
Identity = 54/203 (26.60%), Postives = 99/203 (48.77%), Query Frame = 1
Query:  142 IINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVK-LRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +I  V SI FY+    +KC  E++  +++  G Y+I     N K  +K +   G H++           K    +G F+FTT  +  F+VC  + S      V   +I LD +    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN+R+L++S      L+ +  WQ+  L+ FF +KKL
Sbjct:   16 VIQSVLSISFYLPVRSRKCLREEIHKDVLVTGEYEISE-QPNTKTNLKITDSSG-HILYV---------KEDATKGKFAFTTEDYDMFEVCFESKSPMGTGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKL 207          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 77.0258 bits (188), Expect = 1.143e-16
Identity = 54/203 (26.60%), Postives = 99/203 (48.77%), Query Frame = 1
Query:  142 IINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVK-LRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +I  V SI FY+    +KC  E++  +++  G Y+I     N K  +K +   G H++           K    +G F+FTT  +  F+VC  + S      V   +I LD +    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN+R+L++S      L+ +  WQ+  L+ FF +KKL
Sbjct:   16 VIQSVLSISFYLPVRSRKCLREEIHKDVLVTGEYEISE-QPNTKTNLKITDSSG-HILYV---------KEDATKGKFAFTTEDYDMFEVCFESKSPMGTGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKL 207          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Xenopus
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:496564])

HSP 1 Score: 150.214 bits (378), Expect = 4.878e-44
Identity = 74/210 (35.24%), Postives = 126/210 (60.00%), Query Frame = 1
Query:  124 IWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            + +L        S++F++ E EKKCF+E++ D  +  G Y+ + +D  ++ Y+  +   G+ V V D D  +I+S+ Y  EG F+FT+H  GE ++C+ + S   A      LR++LD +  E A+DY+D   +  L+  + +++ +I  +  I  +QNYQR +EE+FR+T   T+ R+LWWS  Q  +L+ +G WQ+ +LK FF +KKL
Sbjct:   31 LLLLAACFGPAFSLYFHIGETEKKCFIEEIPDETMVVGNYRTQMFDKQREDYLPATPGLGMFVEVKDPDDKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSTKFALFAGGMLRVHLDIQVGEHANDYVDIAAKDKLNTLQLRVRQLIEQVEQIQKEQNYQRWREERFRQTSESTSQRVLWWSIAQTLILVTIGVWQMKHLKGFFEAKKL 240          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Xenopus
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:NCBI gene;Acc:548496])

HSP 1 Score: 147.132 bits (370), Expect = 5.167e-43
Identity = 72/210 (34.29%), Postives = 129/210 (61.43%), Query Frame = 1
Query:  130 ILLCIINY--VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +LL I+ +     ++F++ E EK+CF+E++ D  +  G YK + +D   + ++  +   G+HV V D DG +I+S+ Y  EG F+FT+H  GE ++C+  ++  +++    KLR++LD +  E  ++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:   18 LLLGILQFGLSRGLYFHIGETEKRCFIEEIPDETMVIGNYKTQLWDKQSETFLPSTPGLGMHVEVKDSDGKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSTRMSFFAGGKLRVHLDIQIGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRLTSESTNQRVLWWSIAQTLILILTGIWQMRHLKSFFEAKKL 227          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Xenopus
Match: thnsl1 (threonine synthase like 1 [Source:Xenbase;Acc:XB-GENE-982922])

HSP 1 Score: 117.087 bits (292), Expect = 1.570e-31
Identity = 63/198 (31.82%), Postives = 113/198 (57.07%), Query Frame = 1
Query:  160 SIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETV--KLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +++F++ E E+KC +EDL    +  G YKI+ +D  +  ++  +   G+ V V   +G++++SK Y  +G F+FT+H  GE  +C+ + S   I  V  KLRI+ D ++ E+  D+     +  + +    ++ +   + +I+ QQ YQR +EE +R     TN+ +LWW+ +Q  +L  VG WQI + K F  +KK+
Sbjct:   20 AMYFHVAEKEEKCLIEDLPSETLVTGRYKIQKWDLKEHDFLPSAPGLGMVVTVTAPNGEVLLSKLYGPDGKFTFTSHSPGEHTICLQSNSTNLIAFVSNKLRIHFDIQSGENPLDFHIINAKDKVKEVTYGLEHLRGEINHIIKQQEYQREREEHYRGKSEETNNNVLWWAIIQTAILTSVGIWQIKHFKDFLIAKKV 217          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Xenopus
Match: enpp7 (ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:Xenbase;Acc:XB-GENE-996993])

HSP 1 Score: 77.411 bits (189), Expect = 1.064e-16
Identity = 54/207 (26.09%), Postives = 99/207 (47.83%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLR-IYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +L C   YV  I F +    +KC  E++  N++  G Y  E  +A+ +  V+    D    I+Y        SK    +G F+FTT ++  F+VC  +   A    V  + + L  +    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN R+L++S      L+ +  WQ+  L+ FF +KKL
Sbjct:   11 LLFC--GYVQPISFSLPPNSRKCLREEIHKNVLVTGEY--ELSEAHNQGQVRLKITDSAGHILY--------SKEDASKGKFAFTTEEYDMFEVCFDSKLPAGAGRVPDQMVNLIMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNVRVLYFSIFSMCCLMGLATWQVFYLRRFFKAKKL 205          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Xenopus
Match: enpp7 (ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:Xenbase;Acc:XB-GENE-996993])

HSP 1 Score: 74.3294 bits (181), Expect = 1.801e-15
Identity = 53/211 (25.12%), Postives = 99/211 (46.92%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKK-----STHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +L C   YV  I F +    +KC  E++  N++  G Y++     NQ  +++      +  D    I+Y        SK    +G F+FTT ++  F+VC  +      + V L +    E    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN R+L++S      L+ +  WQ+  L+ FF +KKL
Sbjct:   11 LLFC--GYVQPISFSLPPNSRKCLREEIHKNVLVTGEYELSEAH-NQAGFIRSHLSFLNITDSAGHILY--------SKEDASKGKFAFTTEEYDMFEVCFDSAGRVPDQMVNLIMKHGVE----AKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNVRVLYFSIFSMCCLMGLATWQVFYLRRFFKAKKL 206          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Mouse
Match: Tmed9 (transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761])

HSP 1 Score: 149.443 bits (376), Expect = 6.714e-44
Identity = 69/198 (34.85%), Postives = 123/198 (62.12%), Query Frame = 1
Query:  160 SIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +++F++ E EKKCF+E++ D  +  G Y+ + YD  ++ Y   +   G+ V V D +  +I+++ Y  EG F+FT+H  GE ++C+ + S   +      LR++LD +  E A+DY +   +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +G WQ+ +LK+FF +KKL
Sbjct:   37 ALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKL 234          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Mouse
Match: Tmed4 (transmembrane p24 trafficking protein 4 [Source:MGI Symbol;Acc:MGI:1915070])

HSP 1 Score: 144.05 bits (362), Expect = 5.654e-42
Identity = 68/211 (32.23%), Postives = 126/211 (59.72%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
             + +L         ++F++ E EK+CF+E++ D  +  G Y+ + +D  ++ ++  +   G+HV V D DG +++S+ Y  EG F+FT+H  G+ ++C+  ++  +A     KLR++LD +  E A++Y +   +  L + + + + ++  +  I  +Q+YQR +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:   16 GLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKL 226          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Mouse
Match: Tmed9 (transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761])

HSP 1 Score: 126.331 bits (316), Expect = 2.875e-35
Identity = 60/173 (34.68%), Postives = 105/173 (60.69%), Query Frame = 1
Query:  235 GYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            G Y+ + YD  ++ Y   +   G+ V V D +  +I+++ Y  EG F+FT+H  GE ++C+ + S   +      LR++LD +  E A+DY +   +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +G WQ+ +LK+FF +KKL
Sbjct:   36 GNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKL 208          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Mouse
Match: Tmed11 (transmembrane p24 trafficking protein 11 [Source:MGI Symbol;Acc:MGI:1914616])

HSP 1 Score: 120.939 bits (302), Expect = 4.152e-33
Identity = 67/209 (32.06%), Postives = 119/209 (56.94%), Query Frame = 1
Query:  130 ILLCI-INYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIE--TVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ILLC   ++  + +F+  E E+KC +ED+  + +  G +K++ +D  +  +++ +   G+ V V   + ++++SK Y  +G F FT+H  GE  +C+ + S  ++     KLRI+LD    E   D      +  +++   K++ +I  +  IL +Q+YQR +EE FR T   TN  +LWW+F Q  + + VG +Q+ +LK FF +KKL
Sbjct:    6 ILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKVQQWDIVRHDFLESAPGLGMFVTVTTYNDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQVEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMKHLKDFFIAKKL 214          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Mouse
Match: Tmed4 (transmembrane p24 trafficking protein 4 [Source:MGI Symbol;Acc:MGI:1915070])

HSP 1 Score: 80.1073 bits (196), Expect = 4.690e-18
Identity = 42/163 (25.77%), Postives = 89/163 (54.60%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQR 603
             + +L         ++F++ E EK+CF+E++ D  +         +D  ++ ++  +   G+HV V D DG +++S+ Y  EG F+FT+H  G+ ++C+  ++  +A     KLR++LD +  E A++Y +   +  L + + + + ++  +  I  +Q+YQR
Sbjct:   16 GLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMM--------WDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQR 170          
BLAST of Transmembrane emp24 domain-containing protein eca vs. UniProt/SwissProt
Match: sp|B4NKL0|TMEDE_DROWI (Transmembrane emp24 domain-containing protein eca OS=Drosophila willistoni OX=7260 GN=eca PE=3 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 1.270e-53
Identity = 82/208 (39.42%), Postives = 131/208 (62.98%), Query Frame = 1
Query:  124 IWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            + +LLC +N    ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  +I+S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFWQ+ +LK+FF +KKL
Sbjct:    8 VALLLCALNSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKVILSRVYSSQGRISFTSHTPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVDQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. UniProt/SwissProt
Match: sp|B3NZM5|TMEDE_DROER (Transmembrane emp24 domain-containing protein eca OS=Drosophila erecta OX=7220 GN=eca PE=3 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 2.090e-53
Identity = 81/209 (38.76%), Postives = 133/209 (63.64%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++ ++LCI++    ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  I++S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFWQ+ +LK+FF +KKL
Sbjct:    7 SLALMLCILHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. UniProt/SwissProt
Match: sp|B4PVC6|TMEDE_DROYA (Transmembrane emp24 domain-containing protein eca OS=Drosophila yakuba OX=7245 GN=eca PE=3 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 2.831e-53
Identity = 80/209 (38.28%), Postives = 133/209 (63.64%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++ ++LC+++    ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  I++S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFWQ+ +LK+FF +KKL
Sbjct:    7 SLALMLCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. UniProt/SwissProt
Match: sp|B4JG34|TMEDE_DROGR (Transmembrane emp24 domain-containing protein eca OS=Drosophila grimshawi OX=7222 GN=eca PE=3 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 3.672e-53
Identity = 80/206 (38.83%), Postives = 131/206 (63.59%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++LC ++    ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  +I+S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  ++ I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFWQ+ +LK+FF +KKL
Sbjct:   10 LMLCALHSASGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKVILSRVYSSQGRISFTSHTPGEHVICMYSNSTAWFNGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVQQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. UniProt/SwissProt
Match: sp|B4HJV5|TMEDE_DROSE (Transmembrane emp24 domain-containing protein eca OS=Drosophila sechellia OX=7238 GN=eca PE=3 SV=1)

HSP 1 Score: 174.481 bits (441), Expect = 4.274e-53
Identity = 80/209 (38.28%), Postives = 133/209 (63.64%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++ ++LC+++    ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  I++S+ Y+ +G  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q  VL+C+GFWQ+ +LK+FF +KKL
Sbjct:    7 SLALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTIVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. TrEMBL
Match: A0A1W0XB29 (Transmembrane emp24 domain-containing protein 9 OS=Hypsibius dujardini OX=232323 GN=BV898_01574 PE=3 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 5.987e-53
Identity = 89/206 (43.20%), Postives = 132/206 (64.08%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            IL  +I   + ++F++ E EKKCFLE++ D  +  G YK+E++D N   YV      G+ V V D D  II+S+AY  EG F+FT+H  GE  +C+ST S  W     LR++LD    E A+DY +   R  L + + +++ ++  +  I  +QNYQR++EE+FR+T   TNSR+LWW+FMQ  VLL +GFWQ+ +LK+FF +KKL
Sbjct:   10 ILALLICSSNGLYFHLGETEKKCFLEEIPDETMVVGKYKVEFHDINMNQYVHVPPGMGMLVEVKDPDQKIIMSRAYGAEGKFTFTSHTPGEHTMCLSTNSSKWFGGSSLRVHLDISIGEHANDYKEIAARDKLSELQLRVRQLLDQVDQITKEQNYQRVREERFRQTSESTNSRVLWWAFMQTAVLLAIGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. TrEMBL
Match: A0A443S678 (Transmembrane emp24 domain-containing protein eca-like protein OS=Leptotrombidium deliense OX=299467 GN=B4U80_00725 PE=3 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 1.624e-52
Identity = 84/208 (40.38%), Postives = 135/208 (64.90%), Query Frame = 1
Query:  124 IWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            + + L  +N   +++F++ E E+KCF+E++ D  +  G YKIE +D N + Y++ S+  G+HV V D D   I+SK Y+ EG FSFT+H  GE  +C+ + S  W    +LR++LD +  E A DY +   ++ L + + +++ ++  +  I  +QNYQR +EE+FR+T   TNSR+LWWSF Q  +LL +GFWQ+ +LK+FF +KKL
Sbjct:    8 VAVFLVYLNCSFALYFHIGETERKCFIEEIPDETLVVGKYKIELHDPNTRGYMQTSSAFGMHVEVRDPDDKTILSKVYSAEGKFSFTSHTPGEHVICLYSNSTRWFAGAQLRVHLDIQVGEHAIDYANVAQKEKLSELQLRVRQLLDQVEQISKEQNYQRYREERFRQTSESTNSRVLWWSFGQTLILLSMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. TrEMBL
Match: A0A2C9K3I7 (GOLD domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106079898 PE=3 SV=1)

HSP 1 Score: 177.563 bits (449), Expect = 7.357e-52
Identity = 80/213 (37.56%), Postives = 133/213 (62.44%), Query Frame = 1
Query:  109 MLIENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            M +    ++ C+  Y ++++F++ E E+KCF+E++ D  +  G+YK++ YD N K Y+  S   G+HV V D +  +++S+ Y  EG F+FT+H  GE  +C+++ S AW    +LR++LD    E A DY     +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS  Q  +LL  GFWQ+ +LK+FF +KKL
Sbjct:    1 MALTTALVVFCLFLYTNALYFHIGETERKCFIEEIPDETMVVGHYKVQAYDHNAKDYMPVSPDIGMHVEVSDPESKVVLSRTYAAEGRFTFTSHSAGEHIICLNSNSSAWFNAGQLRVHLDINVGEHAVDYQQVQAKDKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILLITGFWQMQHLKSFFEAKKL 213          
BLAST of Transmembrane emp24 domain-containing protein eca vs. TrEMBL
Match: A0A034WPT5 (Transmembrane emp24 domain-containing protein eca OS=Bactrocera dorsalis OX=27457 GN=TMEDE PE=3 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 1.094e-51
Identity = 83/206 (40.29%), Postives = 130/206 (63.11%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +LLC++     ++F++ E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  +I+S+ Y+ EG  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q FVL+C+GFWQ+ +LK+FF +KKL
Sbjct:   10 VLLCVLQTTFGLYFHIAETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKVILSRVYSSEGRISFTSHIPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVDQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTFVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. TrEMBL
Match: W8C7B1 (Transmembrane emp24 domain-containing protein eca OS=Ceratitis capitata OX=7213 GN=TMEDE PE=2 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 2.336e-51
Identity = 82/206 (39.81%), Postives = 130/206 (63.11%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +L C++     ++F+++E E+KCF+E++ D       YK+E YD     ++  S   G+HV V D D  +I+S+ Y+ EG  SFT+H  GE  +C+ + S AW    +LR++LD +  E A DY +   ++ L + + +I+ ++  +  I  +QNYQR +EE+FR T   TNSR+LWWS  Q FVL+C+GFWQ+ +LK+FF +KKL
Sbjct:   10 VLFCVLQTTFGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKVILSRVYSSEGRISFTSHIPGEHVICMYSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVDQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTFVLVCMGFWQMRHLKSFFEAKKL 215          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Cavefish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:103030438])

HSP 1 Score: 145.976 bits (367), Expect = 7.345e-43
Identity = 75/222 (33.78%), Postives = 134/222 (60.36%), Query Frame = 1
Query:  109 MLIENIWILLC---IINY----VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            M++  +   LC   ++N+    V +++F++ E EKKCF+E++ D  +  G Y+ + YD  ++ Y+  +   G+ V V D D  +I+S+ Y  EG F+FT+H  GE ++C+ + S   +      LR++LD +  E  ++Y     +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +GFWQ+ +LK+FF +KKL
Sbjct:    1 MVVFRMQFTLCTVLVLNFCYSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFAGGMLRVHLDIQVGEHTNNYEVIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKL 222          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Cavefish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:103030438])

HSP 1 Score: 145.591 bits (366), Expect = 1.316e-42
Identity = 71/200 (35.50%), Postives = 124/200 (62.00%), Query Frame = 1
Query:  154 VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSV--AWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            V +++F++ E EKKCF+E++ D  +  G Y+ + YD  ++ Y+  +   G+ V V D D  +I+S+ Y  EG F+FT+H  GE ++C+ + S   +      LR++LD +  E  ++Y     +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +GFWQ+ +LK+FF +KKL
Sbjct:   32 VSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFAGGMLRVHLDIQVGEHTNNYEVIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKL 231          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Cavefish
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:ZFIN;Acc:ZDB-GENE-040625-140])

HSP 1 Score: 142.124 bits (357), Expect = 2.488e-41
Identity = 67/216 (31.02%), Postives = 127/216 (58.80%), Query Frame = 1
Query:  106 IMLIENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++    + +L    +   +++F++ E EKKCF+E++ D  +  G Y+ + +D    +++  +   G+HV + D D  +I+S+ Y  +G F+FT+H  GE ++C+  ++  +A     KLR++LD +  E  ++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR T   TN R+LWWS  Q  +L+    WQ+ +LK+FF +KKL
Sbjct:   10 VVCAAGLLLLFAWFSPSRALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQTGSFLPATPGLGMHVEIKDPDTKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTIILITAAIWQMRHLKSFFEAKKL 225          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Cavefish
Match: si:ch211-255i20.3 (transmembrane emp24 domain-containing protein 11-like [Source:NCBI gene;Acc:103034721])

HSP 1 Score: 112.079 bits (279), Expect = 1.242e-29
Identity = 61/205 (29.76%), Postives = 117/205 (57.07%), Query Frame = 1
Query:  139 CIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAW--IETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            C ++   +++F + +  +KC +E++ ++++  GY+ +E++D  ++     S H G+ V V D + ++++ K +   G F+FT+H  G+  +C+ + S  +      +L+++LD +  E   D      ++     + +++ +I  M+ I  QQ++QR +EE FRE    TN  +LWW+ +Q  +LL VGFWQ+ NLK F   KKL
Sbjct:   30 CFVSLSFAMYFDLVDQREKCIIEEIPEDVLVTGYFFVEHWDEKKQ---DNSPHLGVTVTVRDPNNEVLLMKRFGRYGKFTFTSHASGQHFLCVKSNSTRFSAFAGERLKVHLDVQMGEHTIDPSAEKAKETFKTMEYRMQHLIDQMQYISKQQDFQREREELFREMSETTNGSVLWWALIQTSILLTVGFWQMRNLKNFLIEKKL 231          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Cavefish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:103042340])

HSP 1 Score: 73.9442 bits (180), Expect = 1.346e-15
Identity = 53/201 (26.37%), Postives = 99/201 (49.25%), Query Frame = 1
Query:  148 NYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLR-IYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            + V SI F++    +KC  E++  +++  G Y+I     N K  +K +   G H++          SK    +G F+FTT  +  F+VC  + S      V  + I LD +    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN+R+L++S      L+ +  WQ+  L+ FF +KKL
Sbjct:   15 DSVFSISFFLPVRTRKCLKEEIHKDVLVTGEYEISE-QPNTKTNLKITDSSG-HIL---------YSKEDATKGKFAFTTEDYDMFEVCFESKSQMGTGRVPDQLINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKL 204          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001929.1 (pep scaffold:Pmarinus_7.0:GL476868:73855:89088:-1 gene:ENSPMAG00000001745.1 transcript:ENSPMAT00000001929.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 137.117 bits (344), Expect = 1.246e-40
Identity = 66/175 (37.71%), Postives = 111/175 (63.43%), Query Frame = 1
Query:  229 FKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            F G YK + +D N++ ++  +   G+HV V D DG +I+SK Y+ EG F+FT+H  GE ++C+  ++  +A     +LR++LD +  E A+DY +   +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:    1 FTGNYKTQLWDKNKQEFLPSTPGLGMHVEVKDPDGKVILSKQYSSEGRFTFTSHTPGEHQICLHSNSTKIALFAGGRLRVHLDIQVGEHANDYSEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILITTGIWQMRHLKSFFEAKKL 175          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Sea Lamprey
Match: tmed3 (transmembrane p24 trafficking protein 3 [Source:ZFIN;Acc:ZDB-GENE-030131-8335])

HSP 1 Score: 55.8398 bits (133), Expect = 9.900e-10
Identity = 46/198 (23.23%), Postives = 89/198 (44.95%), Query Frame = 1
Query:  163 IHFYMNEGEKKCFLEDLQDNIIFKGYYKI---EYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQ-DLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKK 744
            + F + +  K+CF ED+   +     +++     YD + +    K  HD    ++Y+ +     S        +++TT + G +++C S     +       +Y D +  E A  + D   R   L Q ++    I   ++++ + Q   R++E + R      NSR+  WS  +  +L+ VG  Q++ LK+FF  KK
Sbjct:   45 VTFELKDNAKQCFYEDIDQGVKVTLDFQVITGGNYDVDCRV---KGPHDS---VLYNENRKQYDS--------YAWTTEQRGTYEICFSNEFSTFTHKT---VYFDLQVGEEAPLFRDEGTRVVALTQMESACVTIHEGLKSVDNYQTQHRLQETQDRHQAEVLNSRVNMWSIGETIILVVVGVGQVMLLKSFFSDKK 225          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Sea Lamprey
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-269])

HSP 1 Score: 48.521 bits (114), Expect = 1.097e-7
Identity = 36/128 (28.12%), Postives = 61/128 (47.66%), Query Frame = 1
Query:  367 GFFSFTTHKFGEFKVCIST-VSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            G ++F  H  G +K C    +S    + V   I +  ET +  D  M+T   Q+  + +  I  +   M  +  +Q Y  ++E   R     TNSR++ W+F +A VL+ +   QI  LK FF  +++
Sbjct:   20 GKYTFAAHMDGVYKFCFGNKMSTMTPKMVMFTIDMG-ETPKGQD--METEAHQN--KLEEMINELATAMTAVKHEQEYMEVRERIHRSVNDNTNSRVVLWAFFEALVLVAMTLGQIYYLKRFFEVRRV 142          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Yeast
Match: ERP6 (Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002970])

HSP 1 Score: 97.8265 bits (242), Expect = 2.911e-25
Identity = 61/219 (27.85%), Postives = 114/219 (52.05%), Query Frame = 1
Query:  109 MLIENIWILLCIINY-VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVI----VYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKLF 750
            ML   I++   ++ + V + +FY   G++KCFL++L  + + KG Y +E YD     Y   S +D   VI    V+D +  ++  +  +  G FSF   + GE+K+C+ +    W+   K ++ ++FE    A   +D   ++ L+    K+  +   + +I  +Q   R +EE FR+     NSR +WW+  Q  +L+ +  WQ+ +L++FF  +K+ 
Sbjct:    1 MLSHYIFLAFVLLPFRVSAFYFYGYGGDRKCFLKELSKDTLLKGSYNLEVYDDKLADYALPSYNDYGIVIDVEEVFDNNHRVVHQQG-SPSGDFSFLALESGEYKICLQSRVNNWVGKTKTKLEIEFEVGFEA--MLDMQRKETLESLHGKVSILNSKIVDIRREQQLMREREESFRDISESVNSRAMWWTVTQVTLLIIICVWQMKSLRSFFVKQKVL 216          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Yeast
Match: ERP1 (Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms heterotrimeric complex with Erp2p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP1 has a paralog, ERP6, that arose from the whole genome duplication [Source:SGD;Acc:S000002129])

HSP 1 Score: 87.8113 bits (216), Expect = 1.835e-21
Identity = 56/229 (24.45%), Postives = 102/229 (44.54%), Query Frame = 1
Query:  100 LFIMLIENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHD-GL-----------HVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKLF 750
            L   L++     L +   V + ++Y +  E+KCF ++L    +F+  YK + YD   + Y      D G+           H++V+         +  +  G  +F     GE K+CI   +  W+   K +I ++F+    +D+ +D+  +  +D   AK+  +   +  I  +Q   R +E  FR+     NSR +WW  +Q  VL     WQ+ +L  FF  +K+ 
Sbjct:    2 LLTSLLQVFACCLVLPAQVTAFYYYTSGAERKCFHKELSKGTLFQATYKAQIYDDQLQNYRDAGAQDFGVLIDIEETFDDNHLVVH---------QKGSASGDLTFLASDSGEHKICIQPEAGGWLIKAKTKIDVEFQVG--SDEKLDSKGKATIDILHAKVNVLNSKIGEIRREQKLMRDREATFRDASEAVNSRAMWWIVIQLIVLAVTCGWQMKHLGKFFVKQKIL 219          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Yeast
Match: ERP5 (Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport [Source:SGD;Acc:S000001152])

HSP 1 Score: 70.8626 bits (172), Expect = 2.278e-15
Identity = 50/214 (23.36%), Postives = 101/214 (47.20%), Query Frame = 1
Query:  112 LIENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXX--XXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++  I +L  I   V ++HFY   GE KCF E L    +  G   ++ Y   +    ++     L + V +   +   ++++  +  G  +FT    GE + C +       ++  LR++++ E      + +D+  ++D++  K ++  +   + +I  +Q+  R KE +FR      NS+++ WS  Q  +LL    +Q+  LK FF  +K+
Sbjct:    5 IVHGICLLFAITQAVGAVHFYAKSGETKCFYEHLSRGNLLIG--DLDLY-VEKDGLFEEDPESSLTITVDETFDNDHRVLNQKNSHTGDVTFTALDTGEHRFCFTPFYSK--KSATLRVFIELEIGNV--EALDSKKKEDMNSLKGRVGQLTQRLSSIRKEQDAIREKEAEFRNQSESANSKIMTWSVFQLLILLGTCAFQLRYLKNFFVKQKV 211          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Yeast
Match: ERV25 (Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, [Source:SGD;Acc:S000004473])

HSP 1 Score: 51.6026 bits (122), Expect = 1.824e-8
Identity = 32/125 (25.60%), Postives = 58/125 (46.40%), Query Frame = 1
Query:  376 SFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKLF 750
            +FT      F VC    +     ++   I LD E+   A D+      + L   + +++ +  I   I+ +  Y + +EE+ R+T   TN R+  +S +   VL  +G WQ+  LK +F +K + 
Sbjct:   87 AFTAPSSTAFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII 211          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Yeast
Match: EMP24 (Component of the p24 complex; role in misfolded protein quality control; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles [Source:SGD;Acc:S000003168])

HSP 1 Score: 47.3654 bits (111), Expect = 3.922e-7
Identity = 50/217 (23.04%), Postives = 89/217 (41.01%), Query Frame = 1
Query:  127 WILLCIINYVHSIHFYMNEG-EKKCFLEDLQDNIIFKG---YYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLR------IYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +++ C + +  S H  +     ++CF EDL      KG       ++ D N ++    S   G  +I      +++ +   T  G  + +    G F+ C    +   IET  +       +Y+D          +D  N   LD +   ++ +  + R +  +Q+Y  I+E   R T   TN R+ WWS  Q  V++    +QI  L+ FF    L
Sbjct:    8 FVIACFLFFSASAHNVLLPAYGRRCFFEDLS-----KGDELSISFQFGDRNPQS---SSQLTGDFIIYGPERHEVLKTVRDTSHGEITLSAPYKGHFQYCFLNENTG-IETKDVTFNIHGVVYVD----------LDDPNTNTLDSA---VRKLSKLTREVKDEQSYIVIRERTHRNTAESTNDRVKWWSIFQLGVVIANSLFQIYYLRRFFEVTSL 202          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Nematostella
Match: EDO35953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK51])

HSP 1 Score: 163.696 bits (413), Expect = 3.272e-50
Identity = 83/204 (40.69%), Postives = 126/204 (61.76%), Query Frame = 1
Query:  142 IINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWI--ETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++  V +++F+M E EKKCF+E++ D  +  G YK + YD N K ++  S   G+HV V D +G II+SK Y+ EG F+FT+H  GE  +C+ + S  W      +LRI+LD +  E A+DY     +  L + + +I+ ++  +  I  +QNYQR +EE+FR T   TN R+LWW+  Q  +LL  GFWQ+ +LK FF +KKL
Sbjct:   13 MLGNVQALYFHMGETEKKCFIEEIPDETMVIGKYKTQLYDENIKDFLPSSPGIGMHVEVKDPNGKIIMSKYYSSEGRFTFTSHTPGEHVICLHSNSTRWSLWAGGRLRIHLDIQVGEHANDYAQIAAKDKLTELQLRIRQLLDQVEQISKEQNYQRFREERFRMTSESTNQRVLWWALAQTVILLATGFWQMRHLKGFFEAKKL 216          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Nematostella
Match: EDO41239 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z3])

HSP 1 Score: 65.855 bits (159), Expect = 4.807e-13
Identity = 49/209 (23.44%), Postives = 99/209 (47.37%), Query Frame = 1
Query:  124 IWILLC-IINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            + +L+C  I    S+ F ++ G +KC  E++  +++  G + +   DA Q+    K T    HV            +    +G F+FTT  +  ++VC  + +     + +  + ++ +    A +Y D    + L   + ++K +  +   I++   Y R +E++ R+T   T+SR+L++S      L  +  WQ+  L+ FF +KKL
Sbjct:    9 VPLLICEYILSASSLSFTLSSGNRKCLKEEVHKDVLVTGEFTLS--DAPQQKTNLKVTDSTGHVF---------YKRDDATKGKFAFTTDDYDMYEVCFDSETSHGGGSDR-EVSINIKHGVEAKNYEDLAKAEKLKPMEVELKRLEDLGDAIVNDFAYMRQREQEMRDTNESTHSRVLYFSIFSILCLFGLATWQLFYLRRFFIAKKL 205          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Nematostella
Match: EDO42051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2I7])

HSP 1 Score: 54.6842 bits (130), Expect = 4.492e-9
Identity = 48/221 (21.72%), Postives = 92/221 (41.63%), Query Frame = 1
Query:  124 IWILLCIINYVHSIHFYMNEGEKKCFLEDLQDN--------IIFKGYYKIE--YYDANQKAY--VKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLR-IYLDFETSESADDYMDTLNRQD-LDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKK 744
            +  L CI+     + F + +  ++CF E+L+ +        +I  G Y ++   YD N+K    V+K  +D                         +FT  + G +K C S        T+  + +Y DF++ E         N    L Q +     I   ++  +  Q + R++E + R+   + N R+ WWS  ++ +++ VG  Q+  L+ FF  ++
Sbjct:   13 VLALSCILVSCTELTFELEDNARQCFYEELKKDAKATLEFQVITGGNYDVDVILYDINEKELYSVQKKQYDS-----------------------HTFTVEQPGIYKFCFSN----EFSTISHKTVYFDFQSGEETQLTKTMGNHHTALTQMETACVTIHENLKIAIDYQTHHRLRESQGRDMAEYLNERVQWWSVGESVLIVIVGICQVFILRQFFAERR 206          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Nematostella
Match: EDO31547 (Transmembrane emp24 domain-containing protein [Source:UniProtKB/Swiss-Prot;Acc:A7SXK3])

HSP 1 Score: 51.2174 bits (121), Expect = 5.569e-8
Identity = 31/127 (24.41%), Postives = 55/127 (43.31%), Query Frame = 1
Query:  367 GFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            G ++F  H  G +  C S         V L+  +D   +       D      L +  +++      M  +  +Q Y  ++E   R     TNSR++WWSF ++ VL+ +   Q+  LK FF  +++
Sbjct:   80 GKYTFAAHMDGTYNYCFSNKMSTMTPKV-LKFSMDIGEAPKDTSKEDNAGHDKLSEMVSQLS---EAMTGVKHEQEYMEVRERIHRSINDNTNSRVVWWSFFESLVLVAMTLGQVYYLKRFFEVRRV 202          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Medaka
Match: tmed4 (transmembrane emp24 domain-containing protein 4 [Source:NCBI gene;Acc:101175398])

HSP 1 Score: 149.828 bits (377), Expect = 2.036e-44
Identity = 71/208 (34.13%), Postives = 128/208 (61.54%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +LL  I+ + +++F++ E EKKCF+E++ D  +  G Y+ + +D    +++  +   G+HV + D D  II+S+ Y  +G F+FT+H  GE ++C+  ++  +A     KLR++LD +  E  ++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:   11 LLLSWISSISALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQSGSFLPATPGLGMHVEIKDPDTKIILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSITQTLILIITGIWQMKHLKSFFEAKKL 218          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Medaka
Match: tmed4 (transmembrane emp24 domain-containing protein 4 [Source:NCBI gene;Acc:101175398])

HSP 1 Score: 149.828 bits (377), Expect = 2.166e-44
Identity = 71/208 (34.13%), Postives = 128/208 (61.54%), Query Frame = 1
Query:  130 ILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCI--STVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +LL  I+ + +++F++ E EKKCF+E++ D  +  G Y+ + +D    +++  +   G+HV + D D  II+S+ Y  +G F+FT+H  GE ++C+  ++  +A     KLR++LD +  E  ++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR T   TN R+LWWS  Q  +L+  G WQ+ +LK+FF +KKL
Sbjct:    6 LLLSWISSISALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQSGSFLPATPGLGMHVEIKDPDTKIILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGKLRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSITQTLILIITGIWQMKHLKSFFEAKKL 213          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Medaka
Match: tmed9 (transmembrane emp24 domain-containing protein 9 [Source:NCBI gene;Acc:101173315])

HSP 1 Score: 148.288 bits (373), Expect = 9.850e-44
Identity = 72/198 (36.36%), Postives = 125/198 (63.13%), Query Frame = 1
Query:  160 SIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVK--LRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +++F++ E EKKCF+E++ D  +  G Y+ + YD  ++ Y+  S   G+ V V D D  +I+S+ Y  EG F+FT+H  GE ++C+ + S  +   V   LR++LD +  E A++Y +   +  L + + +++ ++  +  I  +QNYQR +EE+FR+T   TN R+LWWS +Q  +L+ +G WQ+ +LK+FF +KKL
Sbjct:   20 ALYFHIGELEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPASPGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFVGGTLRVHLDIQVGEHANNYAEIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGIWQMRHLKSFFEAKKL 217          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Medaka
Match: si:ch211-255i20.3 (transmembrane emp24 domain-containing protein 11-like [Source:NCBI gene;Acc:101164569])

HSP 1 Score: 120.939 bits (302), Expect = 3.192e-33
Identity = 68/209 (32.54%), Postives = 121/209 (57.89%), Query Frame = 1
Query:  127 WILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAW--IETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            ++LL  +    +++F + E E+KC +E++ ++ + KG++ +  ++ N  ++   S H G+ V V D +  +++SK Y + G F+FT H  G+  +C  T S  +      K++++LD +  E + D    + + +L+  +  +  +   M  I  QQ YQR KEE FR+    TNS+++WW+ +Q  +LLCVGFWQ+  LK FF +KKL
Sbjct:    8 FVLLSYLMLSAAMYFQLGEQEEKCIIEEIPEDTLVKGHFLLVPWNPNMPSH---SPHLGVTVTVKDQNQKVVMSKRYGKLGKFTFTAHMSGQHYLCFQTNSTRFSVFAAEKMKLHLDVQMGEHSIDPSVQMTKDNLEVLEESLMHMREQMTYISRQQEYQREKEELFRQISEDTNSKVVWWAVVQTSLLLCVGFWQMKRLKDFFIAKKL 213          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Medaka
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:101167507])

HSP 1 Score: 73.9442 bits (180), Expect = 1.462e-15
Identity = 51/199 (25.63%), Postives = 97/199 (48.74%), Query Frame = 1
Query:  154 VHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLR-IYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            V+SI F++    +KC  E++  +++  G Y +     N K ++K  T    H +          SK    +G F+FTT  +  F+VC  + S      V  + + LD +    A +Y +    + L   + +++ +  +  +I++   Y + +EE+ R+T   TN+R+L++S      L+ +  WQ+  L+ FF +KKL
Sbjct:   18 VYSISFFLPVNSRKCLREEIHKDVLVTGEYDL-TEQPNTKTHLK-ITDSSTHTL---------YSKEDATKGKFAFTTEDYDMFEVCFESKSPLGTGRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKL 205          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Planmine SMEST
Match: SMESG000058563.1 (SMESG000058563.1)

HSP 1 Score: 331.643 bits (849), Expect = 1.209e-116
Identity = 170/171 (99.42%), Postives = 171/171 (100.00%), Query Frame = 1
Query:  235 GYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            GYYKIEYYDANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKK+
Sbjct:    5 GYYKIEYYDANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKI 175          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Planmine SMEST
Match: SMESG000058563.1 (SMESG000058563.1)

HSP 1 Score: 331.257 bits (848), Expect = 1.587e-116
Identity = 170/171 (99.42%), Postives = 171/171 (100.00%), Query Frame = 1
Query:  235 GYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            GYYKIEYYDANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKK+
Sbjct:    4 GYYKIEYYDANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKI 174          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Planmine SMEST
Match: SMESG000073800.1 (SMESG000073800.1)

HSP 1 Score: 147.902 bits (372), Expect = 9.432e-44
Identity = 78/209 (37.32%), Postives = 134/209 (64.11%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +I++ + I+N  ++I+F++ E E KCF+E++ ++ +  G YK E +D ++  YV   +  G+HV + D +  +++S+ Y+ EG F  TTH  GEF +C+ + S  W    KLR++L+ +T E A DY +   +  L   + +++ +I  +  I  +QNYQR +E +FR+T   TNSR+L++S +Q  +L+ VGFWQ+ NLK+FF +KKL
Sbjct:    7 SIFLSVFILN-TNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKL 214          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Planmine SMEST
Match: SMESG000073800.1 (SMESG000073800.1)

HSP 1 Score: 147.902 bits (372), Expect = 1.045e-43
Identity = 78/209 (37.32%), Postives = 134/209 (64.11%), Query Frame = 1
Query:  121 NIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYYDANQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            +I++ + I+N  ++I+F++ E E KCF+E++ ++ +  G YK E +D ++  YV   +  G+HV + D +  +++S+ Y+ EG F  TTH  GEF +C+ + S  W    KLR++L+ +T E A DY +   +  L   + +++ +I  +  I  +QNYQR +E +FR+T   TNSR+L++S +Q  +L+ VGFWQ+ NLK+FF +KKL
Sbjct:   11 SIFLSVFILN-TNAIYFHIRETESKCFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKL 218          
BLAST of Transmembrane emp24 domain-containing protein eca vs. Planmine SMEST
Match: SMESG000024933.1 (SMESG000024933.1)

HSP 1 Score: 77.7962 bits (190), Expect = 4.202e-17
Identity = 59/215 (27.44%), Postives = 106/215 (49.30%), Query Frame = 1
Query:  121 NIWIL-LCIINYVH---SIHFYMNE-GEKKCFLEDLQDNIIFKGYYKIEYYDA-NQKAYVKKSTHDGLHVIVYXXXXXXXXSKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKL 747
            N +I+ L I+N+++   +I F++   G KKC  E++  N++  G Y I   DA  QKA ++  T    HV+           K    +G F+FTT ++  F VC+ T  +   +     ++LD +      +Y      + L   + ++K +  +   I+    Y R +EEK R+T   T++R+ ++S      L+ +  WQ++ L+ +F SKKL
Sbjct:    2 NFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDIT--DAPGQKASIQ-VTDSKSHVL---------YQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKL 204          
The following BLAST results are available for this feature:
BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMED94.092e-4432.71transmembrane p24 trafficking protein 9 [Source:HG... [more]
TMED41.113e-4133.50transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED41.910e-2327.27transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED42.512e-2128.29transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED102.768e-1526.77transmembrane p24 trafficking protein 10 [Source:H... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Y60A3A.96.045e-5039.51pep chromosome:WBcel235:V:19946691:19949093:-1 gen... [more]
T08D2.11.335e-2637.68pep chromosome:WBcel235:X:162529:163134:-1 gene:WB... [more]
F47G9.13.003e-1826.29pep chromosome:WBcel235:V:11323965:11326964:-1 gen... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eca1.301e-5338.28gene:FBgn0069242 transcript:FBtr0082098[more]
p24-24.200e-4836.41gene:FBgn0053105 transcript:FBtr0082093[more]
p24-24.200e-4836.41gene:FBgn0053105 transcript:FBtr0303038[more]
bai1.946e-1124.63gene:FBgn0045866 transcript:FBtr0084758[more]
p24-19.848e-724.22gene:FBgn0030341 transcript:FBtr0073604[more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed94.304e-4436.36transmembrane p24 trafficking protein 9 [Source:ZF... [more]
tmed41.638e-4232.21transmembrane p24 trafficking protein 4 [Source:ZF... [more]
si:ch211-255i20.38.534e-3131.25si:ch211-255i20.3 [Source:ZFIN;Acc:ZDB-GENE-141216... [more]
tmed101.143e-1626.60transmembrane p24 trafficking protein 10 [Source:Z... [more]
tmed101.143e-1626.60transmembrane p24 trafficking protein 10 [Source:Z... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed94.878e-4435.24transmembrane p24 trafficking protein 9 [Source:NC... [more]
tmed45.167e-4334.29transmembrane p24 trafficking protein 4 [Source:NC... [more]
thnsl11.570e-3131.82threonine synthase like 1 [Source:Xenbase;Acc:XB-G... [more]
enpp71.064e-1626.09ectonucleotide pyrophosphatase/phosphodiesterase 7... [more]
enpp71.801e-1525.12ectonucleotide pyrophosphatase/phosphodiesterase 7... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tmed96.714e-4434.85transmembrane p24 trafficking protein 9 [Source:MG... [more]
Tmed45.654e-4232.23transmembrane p24 trafficking protein 4 [Source:MG... [more]
Tmed92.875e-3534.68transmembrane p24 trafficking protein 9 [Source:MG... [more]
Tmed114.152e-3332.06transmembrane p24 trafficking protein 11 [Source:M... [more]
Tmed44.690e-1825.77transmembrane p24 trafficking protein 4 [Source:MG... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B4NKL0|TMEDE_DROWI1.270e-5339.42Transmembrane emp24 domain-containing protein eca ... [more]
sp|B3NZM5|TMEDE_DROER2.090e-5338.76Transmembrane emp24 domain-containing protein eca ... [more]
sp|B4PVC6|TMEDE_DROYA2.831e-5338.28Transmembrane emp24 domain-containing protein eca ... [more]
sp|B4JG34|TMEDE_DROGR3.672e-5338.83Transmembrane emp24 domain-containing protein eca ... [more]
sp|B4HJV5|TMEDE_DROSE4.274e-5338.28Transmembrane emp24 domain-containing protein eca ... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1W0XB295.987e-5343.20Transmembrane emp24 domain-containing protein 9 OS... [more]
A0A443S6781.624e-5240.38Transmembrane emp24 domain-containing protein eca-... [more]
A0A2C9K3I77.357e-5237.56GOLD domain-containing protein OS=Biomphalaria gla... [more]
A0A034WPT51.094e-5140.29Transmembrane emp24 domain-containing protein eca ... [more]
W8C7B12.336e-5139.81Transmembrane emp24 domain-containing protein eca ... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed97.345e-4333.78transmembrane p24 trafficking protein 9 [Source:NC... [more]
tmed91.316e-4235.50transmembrane p24 trafficking protein 9 [Source:NC... [more]
tmed42.488e-4131.02transmembrane p24 trafficking protein 4 [Source:ZF... [more]
si:ch211-255i20.31.242e-2929.76transmembrane emp24 domain-containing protein 11-l... [more]
tmed101.346e-1526.37transmembrane p24 trafficking protein 10 [Source:N... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000001929.11.246e-4037.71pep scaffold:Pmarinus_7.0:GL476868:73855:89088:-1 ... [more]
tmed39.900e-1023.23transmembrane p24 trafficking protein 3 [Source:ZF... [more]
tmed21.097e-728.13transmembrane p24 trafficking protein 2 [Source:ZF... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
ERP62.911e-2527.85Member of the p24 family involved in ER to Golgi t... [more]
ERP11.835e-2124.45Member of the p24 family involved in ER to Golgi t... [more]
ERP52.278e-1523.36Protein with similarity to Emp24p and Erv25p; memb... [more]
ERV251.824e-825.60Member of the p24 family involved in ER to Golgi t... [more]
EMP243.922e-723.04Component of the p24 complex; role in misfolded pr... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO359533.272e-5040.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412394.807e-1323.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO420514.492e-921.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315475.569e-824.41Transmembrane emp24 domain-containing protein [So... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed42.036e-4434.13transmembrane emp24 domain-containing protein 4 [S... [more]
tmed42.166e-4434.13transmembrane emp24 domain-containing protein 4 [S... [more]
tmed99.850e-4436.36transmembrane emp24 domain-containing protein 9 [S... [more]
si:ch211-255i20.33.192e-3332.54transmembrane emp24 domain-containing protein 11-l... [more]
tmed101.462e-1525.63transmembrane p24 trafficking protein 10 [Source:N... [more]
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BLAST of Transmembrane emp24 domain-containing protein eca vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000058563.11.209e-11699.42SMESG000058563.1[more]
SMESG000058563.11.587e-11699.42SMESG000058563.1[more]
SMESG000073800.19.432e-4437.32SMESG000073800.1[more]
SMESG000073800.11.045e-4337.32SMESG000073800.1[more]
SMESG000024933.14.202e-1727.44SMESG000024933.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011806 ID=SMED30011806|Name=Transmembrane emp24 domain-containing protein eca|organism=Schmidtea mediterranea sexual|type=transcript|length=774bp
ATATTTTAAATTCTCACTTTAGGTTAAAATATTATAAATTCTAATAAATA
AAATTAATGTTAATTTTTGACGAGTTTTTGCTTTTGAAATAAATCTAACT
TGTTTATAATGTTGATTGAAAATATTTGGATTTTACTTTGTATAATTAAT
TATGTACATTCTATTCATTTTTATATGAATGAAGGAGAGAAGAAATGTTT
TCTCGAAGATCTTCAAGACAATATTATCTTTAAAGGATATTATAAAATTG
AATATTATGATGCAAATCAGAAAGCATATGTTAAGAAATCAACACATGAT
GGCTTACATGTGATCGTTTATGACGGAGATGGTGATATCATTATATCAAA
AGCATATACAGAGGAAGGATTTTTTTCTTTTACTACTCACAAATTTGGTG
AATTCAAAGTTTGTATTTCAACAGTTTCTGTGGCATGGATTGAGACCGTG
AAGCTAAGAATTTATTTGGACTTCGAAACTTCAGAATCTGCTGATGATTA
CATGGATACTTTGAATAGGCAAGATTTAGATCAGTCAAAGGCAAAAATAA
AAGCAATAATTCATATTATGAGAAATATACTTTCGCAGCAAAATTATCAA
AGAATAAAAGAAGAAAAATTTCGTGAAACAGTAGCATTTACCAACAGCAG
ATTATTATGGTGGAGTTTTATGCAAGCCTTCGTATTATTATGCGTGGGAT
TTTGGCAAATAATAAATCTTAAAACTTTTTTTCATAGTAAAAAATTGTTT
AATTGAAAATAAAACGATTGGAAA
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protein sequence of SMED30011806-orf-1

>SMED30011806-orf-1 ID=SMED30011806-orf-1|Name=SMED30011806-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=216bp
MLIENIWILLCIINYVHSIHFYMNEGEKKCFLEDLQDNIIFKGYYKIEYY
DANQKAYVKKSTHDGLHVIVYDGDGDIIISKAYTEEGFFSFTTHKFGEFK
VCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAI
IHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQ
IINLKTFFHSKKLFN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR009038GOLD_dom
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0061357positive regulation of Wnt protein secretion
GO:0070863positive regulation of protein exit from endoplasmic reticulum
GO:0090263positive regulation of canonical Wnt signaling pathway
GO:0000003reproduction
GO:0002121inter-male aggressive behavior
GO:0006888ER to Golgi vesicle-mediated transport
GO:0007030Golgi organization
GO:0007275multicellular organism development
GO:0009953dorsal/ventral pattern formation
GO:0034389lipid particle organization
GO:0035220wing disc development
GO:0048042regulation of post-mating oviposition
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0012505endomembrane system
GO:0016020membrane