Disks large-like protein 5

Overview
NameDisks large-like protein 5
Smed IDSMED30011728
Length (bp)4195
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Disks large-like protein 5 (SMED30011728) t-SNE clustered cells

Violin plots show distribution of expression levels for Disks large-like protein 5 (SMED30011728) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Disks large-like protein 5 (SMED30011728) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Disks large-like protein 5 (SMED30011728) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011728

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30011728h1SMcG0001775 dd_Smed_v4_2209_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011728h1SMcG0001775 dd_Smed_v4_2209_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011728h1SMcG0001775 dd_Smed_v4_2209_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30011728h1SMcG0001775 dd_Smed_v4_2209_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Human
Match: DLG5 (discs large MAGUK scaffold protein 5 [Source:HGNC Symbol;Acc:HGNC:2904])

HSP 1 Score: 52.373 bits (124), Expect = 7.828e-6
Identity = 40/179 (22.35%), Postives = 75/179 (41.90%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            ++ RP+++LGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI ++YKS K I++ R     + KV +    + F   +  E  +S    G +    +S+ C  I+  V   Q++ +W+P
Sbjct: 1737 TALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIP 1915
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Human
Match: DLG5 (discs large MAGUK scaffold protein 5 [Source:HGNC Symbol;Acc:HGNC:2904])

HSP 1 Score: 52.373 bits (124), Expect = 7.828e-6
Identity = 40/179 (22.35%), Postives = 75/179 (41.90%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            ++ RP+++LGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI ++YKS K I++ R     + KV +    + F   +  E  +S    G +    +S+ C  I+  V   Q++ +W+P
Sbjct: 1737 TALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIP 1915
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Human
Match: DLG5 (discs large MAGUK scaffold protein 5 [Source:HGNC Symbol;Acc:HGNC:2904])

HSP 1 Score: 51.9878 bits (123), Expect = 9.116e-6
Identity = 73/339 (21.53%), Postives = 132/339 (38.94%), Query Frame = 3 
Query: 3189 ILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSD-----DPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            IL VD T LP          + T   W AW +D   +KI+ G IPS + +++  S      +  +SE  +K    +T +   +    F             +  H H  S G K       K+ +     SSD     + +  + +++   +       ++ RP+++LGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI ++YKS K I++ R     + KV +    + F   +  E  +S    G +    +S+ C  I+  V   Q++ +W+P 
Sbjct:  580 ILYVDDT-LP----------QGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFS-----RRLSMSE--VKDDNSATKTLSAAARRSFF------------RRKHKHKRS-GSK-----DGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVD-----CTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPA 877
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Human
Match: DLG5 (discs large MAGUK scaffold protein 5 [Source:HGNC Symbol;Acc:HGNC:2904])

HSP 1 Score: 51.9878 bits (123), Expect = 9.116e-6
Identity = 73/339 (21.53%), Postives = 132/339 (38.94%), Query Frame = 3 
Query: 3189 ILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSD-----DPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            IL VD T LP          + T   W AW +D   +KI+ G IPS + +++  S      +  +SE  +K    +T +   +    F             +  H H  S G K       K+ +     SSD     + +  + +++   +       ++ RP+++LGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI ++YKS K I++ R     + KV +    + F   +  E  +S    G +    +S+ C  I+  V   Q++ +W+P 
Sbjct:  580 ILYVDDT-LP----------QGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFS-----RRLSMSE--VKDDNSATKTLSAAARRSFF------------RRKHKHKRS-GSK-----DGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVD-----CTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPA 877
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Celegans
Match: zoo-1 (ZO-1 (Zonula Occludens tight junctional protein) Ortholog [Source:UniProtKB/TrEMBL;Acc:H1UBK8])

HSP 1 Score: 56.9954 bits (136), Expect = 1.055e-7
Identity = 68/302 (22.52%), Postives = 131/302 (43.38%), Query Frame = 3 
Query: 2244 KSDVDVSVINQIFIRTIDFNSIAH-SAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLL----------------PFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLK-EGVVCHLKTHFRTVRINIYTVLKL--------IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNS 3071
            K D  + V  + +I+ I    +A    GL EGD ++ IN   +   + E+  N +L      +R +  L +  Q +  +    +  +N +                P  P++P  +  R+ ++  N  R   D S+  R   + S +N  ++N     S+++  +   C+ +   R++  N    +          +++IGG+ VGIFVS  V  DS + ++        ++ GD+ILEVNG N   V  + AV  L  L  +  L++ +       + ++    + FY+++ FS  + D +
Sbjct:   29 KDDFGIVVGCKFYIKEIRNPKLAEKDPGLKEGDSVLRINGQSLEGASLEEV-NKWL------ERSRDKLCLVIQRDVRRGTSRWPSQNTVYERVGSVAATPRHSPSPMLPHMPITQ--RNSHEYVNSPRHRSDGSVERR---VSSPANSQLSNFNGMASSQITTQDYDCYTRQPSRSIDANGVANIMFRKVGGSVGVRVIGGNEVGIFVS-AVAADSPASLHG-------VSCGDRILEVNGRNMRGVTRESAVQLLLGLDDRVSLRLEHARQDFEHVRANQLG-DNFYIRSHFSREKRDKA 309
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Celegans
Match: zoo-1 (ZO-1 (Zonula Occludens tight junctional protein) Ortholog [Source:UniProtKB/TrEMBL;Acc:H1UBK8])

HSP 1 Score: 56.9954 bits (136), Expect = 1.185e-7
Identity = 68/302 (22.52%), Postives = 131/302 (43.38%), Query Frame = 3 
Query: 2244 KSDVDVSVINQIFIRTIDFNSIAH-SAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLL----------------PFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLK-EGVVCHLKTHFRTVRINIYTVLKL--------IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNS 3071
            K D  + V  + +I+ I    +A    GL EGD ++ IN   +   + E+  N +L      +R +  L +  Q +  +    +  +N +                P  P++P  +  R+ ++  N  R   D S+  R   + S +N  ++N     S+++  +   C+ +   R++  N    +          +++IGG+ VGIFVS  V  DS + ++        ++ GD+ILEVNG N   V  + AV  L  L  +  L++ +       + ++    + FY+++ FS  + D +
Sbjct:  121 KDDFGIVVGCKFYIKEIRNPKLAEKDPGLKEGDSVLRINGQSLEGASLEEV-NKWL------ERSRDKLCLVIQRDVRRGTSRWPSQNTVYERVGSVAATPRHSPSPMLPHMPITQ--RNSHEYVNSPRHRSDGSVERR---VSSPANSQLSNFNGMASSQITTQDYDCYTRQPSRSIDANGVANIMFRKVGGSVGVRVIGGNEVGIFVS-AVAADSPASLHG-------VSCGDRILEVNGRNMRGVTRESAVQLLLGLDDRVSLRLEHARQDFEHVRANQLG-DNFYIRSHFSREKRDKA 401
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Celegans
Match: zoo-1 (ZO-1 (Zonula Occludens tight junctional protein) Ortholog [Source:UniProtKB/TrEMBL;Acc:H1UBK8])

HSP 1 Score: 56.9954 bits (136), Expect = 1.244e-7
Identity = 68/302 (22.52%), Postives = 131/302 (43.38%), Query Frame = 3 
Query: 2244 KSDVDVSVINQIFIRTIDFNSIAH-SAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLL----------------PFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLK-EGVVCHLKTHFRTVRINIYTVLKL--------IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNS 3071
            K D  + V  + +I+ I    +A    GL EGD ++ IN   +   + E+  N +L      +R +  L +  Q +  +    +  +N +                P  P++P  +  R+ ++  N  R   D S+  R   + S +N  ++N     S+++  +   C+ +   R++  N    +          +++IGG+ VGIFVS  V  DS + ++        ++ GD+ILEVNG N   V  + AV  L  L  +  L++ +       + ++    + FY+++ FS  + D +
Sbjct:  153 KDDFGIVVGCKFYIKEIRNPKLAEKDPGLKEGDSVLRINGQSLEGASLEEV-NKWL------ERSRDKLCLVIQRDVRRGTSRWPSQNTVYERVGSVAATPRHSPSPMLPHMPITQ--RNSHEYVNSPRHRSDGSVERR---VSSPANSQLSNFNGMASSQITTQDYDCYTRQPSRSIDANGVANIMFRKVGGSVGVRVIGGNEVGIFVS-AVAADSPASLHG-------VSCGDRILEVNGRNMRGVTRESAVQLLLGLDDRVSLRLEHARQDFEHVRANQLG-DNFYIRSHFSREKRDKA 433
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Fly
Match: Dlg5 (gene:FBgn0032363 transcript:FBtr0336631)

HSP 1 Score: 55.0694 bits (131), Expect = 5.442e-7
Identity = 30/103 (29.13%), Postives = 52/103 (50.49%), Query Frame = 3 
Query: 3786 HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
             H I  +S   +  L + +IYPIV+LL +KS KQIR +R   T +I    +   +M+ +    E+ +   I   +    + + C  I + V+  Q + +W+PV
Sbjct: 1812 RHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIRDFGTDKISAKAA--KEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPV 1912

HSP 2 Score: 55.0694 bits (131), Expect = 5.488e-7
Identity = 89/409 (21.76%), Postives = 142/409 (34.72%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLK--------MHELFKEKNL----------------------LPFDPNIPSVR------FTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNT--------------EEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKL-IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERML 3350
            IF+ T+   S A  AGL  GD+++ +    +   T E A N      L+     +++L+  Q+NP K         H L  E  +                      LP  P  PS R       +     D +FT  + + S       I SS ++  +                +E     L            R V +++     L IK+ GG+ VGI+V +V     +     ++        GDQILE NG +   V  + A + ++ L+    + V      L  I  +P   + FY++  F            +G+                    L    L F KD++L VD+T+              T   W AW +D    +   G+IPS   +E  L
Sbjct: 1314 IFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANV-----LRQCGDSFTMLV--QYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQS------DISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSDHAGIRK--------GDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEP--GDSFYIRVGF----------DRTGE--------------------LNEDDLRFVKDEVLYVDNTVF-----------NGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEEL 1658
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Fly
Match: Dlg5 (gene:FBgn0032363 transcript:FBtr0080246)

HSP 1 Score: 55.0694 bits (131), Expect = 5.442e-7
Identity = 30/103 (29.13%), Postives = 52/103 (50.49%), Query Frame = 3 
Query: 3786 HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
             H I  +S   +  L + +IYPIV+LL +KS KQIR +R   T +I    +   +M+ +    E+ +   I   +    + + C  I + V+  Q + +W+PV
Sbjct: 1813 RHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIRDFGTDKISAKAA--KEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPV 1913

HSP 2 Score: 55.0694 bits (131), Expect = 5.488e-7
Identity = 89/409 (21.76%), Postives = 142/409 (34.72%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLK--------MHELFKEKNL----------------------LPFDPNIPSVR------FTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNT--------------EEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKL-IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERML 3350
            IF+ T+   S A  AGL  GD+++ +    +   T E A N      L+     +++L+  Q+NP K         H L  E  +                      LP  P  PS R       +     D +FT  + + S       I SS ++  +                +E     L            R V +++     L IK+ GG+ VGI+V +V     +     ++        GDQILE NG +   V  + A + ++ L+    + V      L  I  +P   + FY++  F            +G+                    L    L F KD++L VD+T+              T   W AW +D    +   G+IPS   +E  L
Sbjct: 1315 IFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANV-----LRQCGDSFTMLV--QYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQS------DISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSDHAGIRK--------GDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEP--GDSFYIRVGF----------DRTGE--------------------LNEDDLRFVKDEVLYVDNTVF-----------NGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEEL 1659
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Fly
Match: Dlg5 (gene:FBgn0032363 transcript:FBtr0080247)

HSP 1 Score: 55.0694 bits (131), Expect = 5.442e-7
Identity = 30/103 (29.13%), Postives = 52/103 (50.49%), Query Frame = 3 
Query: 3786 HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
             H I  +S   +  L + +IYPIV+LL +KS KQIR +R   T +I    +   +M+ +    E+ +   I   +    + + C  I + V+  Q + +W+PV
Sbjct: 1813 RHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIRDFGTDKISAKAA--KEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPV 1913

HSP 2 Score: 55.0694 bits (131), Expect = 5.488e-7
Identity = 89/409 (21.76%), Postives = 142/409 (34.72%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLK--------MHELFKEKNL----------------------LPFDPNIPSVR------FTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNT--------------EEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKL-IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERML 3350
            IF+ T+   S A  AGL  GD+++ +    +   T E A N      L+     +++L+  Q+NP K         H L  E  +                      LP  P  PS R       +     D +FT  + + S       I SS ++  +                +E     L            R V +++     L IK+ GG+ VGI+V +V     +     ++        GDQILE NG +   V  + A + ++ L+    + V      L  I  +P   + FY++  F            +G+                    L    L F KD++L VD+T+              T   W AW +D    +   G+IPS   +E  L
Sbjct: 1315 IFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANV-----LRQCGDSFTMLV--QYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQS------DISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSDHAGIRK--------GDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEP--GDSFYIRVGF----------DRTGE--------------------LNEDDLRFVKDEVLYVDNTVF-----------NGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEEL 1659
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Zebrafish
Match: dlg5a (discs, large homolog 5a (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-3149])

HSP 1 Score: 79.7221 bits (195), Expect = 2.981e-14
Identity = 143/647 (22.10%), Postives = 239/647 (36.94%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHD--NSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTF---SFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEY-------------MIEQSPN-----------------STSKLNNCTIH--HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQL----KDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            IF+  +   SIAH AGL  GD+++  N   +   T + A        L   +Q  ++ I AQ+NP     +++  N       +  V    +       T   H   ++LS +     + S+   T T  PNS               R V +    V   I++ GG+  GIFV  +       E +      + +  GD ILE    N ++   + A   +   +    L+V +       +   P   + FY++  +   + +ELD                                  LSF+KDDIL VD T+       PN    N  T W AW +D   +KI+ G IPS F ++       + F    S   +K    S+ +   +    F             +  H H  S  +     ++  + I T ++   D    + +++   I       +S RP+++LGP  D    ML    P ++              IE+                    + + +N  T    H +  I+   +  LH   IYPIVI + YK+ KQI++ +     + KV++    + F       +DY   ++ I+ G  FP      C  IV  V+  QS+ +W P+
Sbjct: 1403 IFVSKVTGGSIAHQAGLEYGDQLLEYNGINLRNATEQQAR-------LIIGQQCDTITIMAQYNP----HMYQLGNHSRSSSRLEPVSTQSTPQGSGTATPDNHSTIDTLSEQDEGTLTPSSKQTTPTTSPNSFIRMPSESSKKVPEARLVTVRKTQVELGIQLCGGNLRGIFVERL-------EDDSPARGADAVVPGDMILEYGSVNMKNKTVEEAYLEMLKPAETVTLRVQHRLDEFNQVKGTPG--DGFYIRALYDRVAETELD----------------------------------LSFKKDDILYVDDTL-------PN---GNFGT-WMAWQLDENAQKIQRGQIPSKFMMD-------QEFYRRHSMTELKDETGSSKTLSAAARRSFF------------RRKHKHKRSSSKDGKDVVAL-DAISTDSIPFLDDCVSLAYQRVQKID-----CTSPRPVLILGPLVDPVKDMLVKDSPGKFSRCVLEVMKASQQAIERGVKDFLFIDYKRRSGHFDVTTVASINEITDKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIYLRDKVSQKHSKEQFEIAQKIEQDYSKFFTGIVQGGTFPY----ICTQIVTIVDQEQSKVLWTPL 1955
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Zebrafish
Match: dlg5a (discs, large homolog 5a (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-3149])

HSP 1 Score: 79.337 bits (194), Expect = 3.794e-14
Identity = 143/647 (22.10%), Postives = 239/647 (36.94%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHD--NSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTF---SFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEY-------------MIEQSPN-----------------STSKLNNCTIH--HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQL----KDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            IF+  +   SIAH AGL  GD+++  N   +   T + A        L   +Q  ++ I AQ+NP     +++  N       +  V    +       T   H   ++LS +     + S+   T T  PNS               R V +    V   I++ GG+  GIFV  +       E +      + +  GD ILE    N ++   + A   +   +    L+V +       +   P   + FY++  +   + +ELD                                  LSF+KDDIL VD T+       PN    N  T W AW +D   +KI+ G IPS F ++       + F    S   +K    S+ +   +    F             +  H H  S  +     ++  + I T ++   D    + +++   I       +S RP+++LGP  D    ML    P ++              IE+                    + + +N  T    H +  I+   +  LH   IYPIVI + YK+ KQI++ +     + KV++    + F       +DY   ++ I+ G  FP      C  IV  V+  QS+ +W P+
Sbjct: 1371 IFVSKVTGGSIAHQAGLEYGDQLLEYNGINLRNATEQQAR-------LIIGQQCDTITIMAQYNP----HMYQLGNHSRSSSRLEPVSTQSTPQGSGTATPDNHSTIDTLSEQDEGTLTPSSKQTTPTTSPNSFIRMPSESSKKVPEARLVTVRKTQVELGIQLCGGNLRGIFVERL-------EDDSPARGADAVVPGDMILEYGSVNMKNKTVEEAYLEMLKPAETVTLRVQHRLDEFNQVKGTPG--DGFYIRALYDRVAETELD----------------------------------LSFKKDDILYVDDTL-------PN---GNFGT-WMAWQLDENAQKIQRGQIPSKFMMD-------QEFYRRHSMTELKDETGSSKTLSAAARRSFF------------RRKHKHKRSSSKDGKDVVAL-DAISTDSIPFLDDCVSLAYQRVQKID-----CTSPRPVLILGPLVDPVKDMLVKDSPGKFSRCVLEVMKASQQAIERGVKDFLFIDYKRRSGHFDVTTVASINEITDKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIYLRDKVSQKHSKEQFEIAQKIEQDYSKFFTGIVQGGTFPY----ICTQIVTIVDQEQSKVLWTPL 1923
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Zebrafish
Match: dlg5b.1 (discs, large homolog 5b (Drosophila), tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-120206-4])

HSP 1 Score: 54.6842 bits (130), Expect = 1.047e-6
Identity = 41/180 (22.78%), Postives = 75/180 (41.67%), Query Frame = 3 
Query: 3648 TSSKRPLVLLGPHSDTFAMMLASTKPQEY-------MIEQSPNSTSKLNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            ++++RP+++LGP  +    ML    P +Y       M  Q       + +C                            H +  I+   +  LH   IYPIVI + Y++ KQI++ +     + KV++    + F   +  E  +S    G +    +SNTC  I+  V+  Q++ +W+P
Sbjct: 1512 STNRRPVLILGPLVEPIKDMLLREAPGKYCRCLPEGMKAQQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHAVSIYPIVIFIRYRNAKQIKEQKDPVYLRDKVSQKHSKEQFESAQRIEQDYSKYFTGVVQAGALSNTCTQIMAIVDQEQNKVLWIP 1691
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Mouse
Match: Dlg5 (discs large MAGUK scaffold protein 5 [Source:MGI Symbol;Acc:MGI:1918478])

HSP 1 Score: 53.5286 bits (127), Expect = 2.671e-6
Identity = 42/179 (23.46%), Postives = 74/179 (41.34%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            +S RP++LLGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI + YKS K I++ R     + KV +    + F   +  +  +S    G +    +S+ C  I+  V   QS+ +W+P
Sbjct: 1739 TSLRPVLLLGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIP 1917
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Mouse
Match: Dlg5 (discs large MAGUK scaffold protein 5 [Source:MGI Symbol;Acc:MGI:1918478])

HSP 1 Score: 53.5286 bits (127), Expect = 2.712e-6
Identity = 42/179 (23.46%), Postives = 74/179 (41.34%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            +S RP++LLGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI + YKS K I++ R     + KV +    + F   +  +  +S    G +    +S+ C  I+  V   QS+ +W+P
Sbjct: 1716 TSLRPVLLLGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIP 1894
[Close]
BLAST of Disks large-like protein 5 vs. Ensembl Mouse
Match: Dlg5 (discs large MAGUK scaffold protein 5 [Source:MGI Symbol;Acc:MGI:1918478])

HSP 1 Score: 53.1434 bits (126), Expect = 3.519e-6
Identity = 42/179 (23.46%), Postives = 74/179 (41.34%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            +S RP++LLGP  D    ML +  P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYPIVI + YKS K I++ R     + KV +    + F   +  +  +S    G +    +S+ C  I+  V   QS+ +W+P
Sbjct: 1390 TSLRPVLLLGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIP 1568
[Close]
BLAST of Disks large-like protein 5 vs. TrEMBL
Match: A0A023GKY7 (Putative membrane-associated guanylate kinase maguk (Fragment) OS=Amblyomma triste OX=251400 PE=2 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 8.440e-21
Identity = 114/481 (23.70%), Postives = 185/481 (38.46%), Query Frame = 3 
Query: 2754 IKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIP--TKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYM-------------IEQSPNSTS-----------------KLNNCTIH---HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            I ++GG++VGIFV +V  +DS +      S    L  GDQILE NG +  +   + A   L + +    +   YNP     I   P   + FY++  F  + +D SL                                +F KDDIL VD+T+            K  P  W AW++D+  +K++ G IPS +  E  L               MK SL               +  S   +    +        L    FS +S  N       TL+ D P   +   +     + P    S RP++L+GP  +     L    PQ++              +EQ     S                  L +CT H   H +  +S   +  L++ +IYPIVI + +K+ KQIR+++       KV      +M+      ES + H+I+  +  S+++  C  +   V+  Q++ +W+P
Sbjct:  108 ITLLGGNAVGIFVHSV-QEDSPA------SGPAGLLPGDQILEYNGTDLRNATAEEAAYELASNTENVHIIAQYNPERFAEIQEQP--GDSFYVRALFDRTSIDGSL--------------------------------AFHKDDILYVDNTMY-----------KGVPGQWRAWILDQDGQKLKCGFIPSKYKAEEEL--------------LMKRSLLDLEEGGTGRRGSTSTRRSFFRRRRHQQRSREDGKELAS--FSDVSINNSCGGSAGTLAEDVPPTYLRVDRL----NYP----SLRPVILVGPLQEAVVDKLEQDFPQQFQRCPSQPLRGSLQALEQGLQDLSLLDFRRRGSHYECLTLDALRHCTNHKLCHALLDVSLSAVERLNRCQIYPIVIFIKFKTTKQIREVKDSTYLTEKVTTKAAKEMYEHALKIESEYKHLINAVIPGSNLAYMCTQVKMCVDDEQNKALWVP 512
[Close]
BLAST of Disks large-like protein 5 vs. TrEMBL
Match: A0A1E1XBJ2 (Putative membrane-associated guanylate kinase maguk (Fragment) OS=Amblyomma aureolatum OX=187763 PE=2 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 2.439e-18
Identity = 136/584 (23.29%), Postives = 223/584 (38.18%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNS-----TKLKEGVVCHL--KTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHI--PTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYM-------------IEQSPNSTS-----------------KLNNCTIH---HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLR 3902
            IF+ ++  NSIA  A L  GD+++      V  +   +A      N L+  R   ++L+  QFNP K  E+  + N+   + N P                 +   + S ++   + S  + ++N + P+S     T+ K+  V     +   R V +   +    I ++GG++VGIFV + V +DS +      S    L  GDQILE NG +  +   + A   L + +    +   YNP     I   P   + FY++  F  + +D S                                L+F KDDIL VD+T+            K  P  W AW++D+  +K++ G IPS +  E  L               MK SL               +  S   +    +        L    FS +S  N       TL+ D P   +   +     + P    S RP++L+GP  +     L    PQ++              +EQ     S                  L +CT H   H +  +S   +  L++ +IYPIVI + +K+ KQIR+++
Sbjct: 1100 IFVSSVSENSIAAQASLQVGDQLLE-----VCGINMRNATYQLAANVLRQCRDSITMLV--QFNPDKYREVASD-NISTSEENSP-----------------VDTPAASPKMRHSKRSDLIRISNDDVPSSATSTLTRQKQSCVSAKGSRAEPRIVLLRKASPSLGITLLGGNAVGIFV-HSVQEDSPA------SGPAGLLPGDQILEYNGTDLRNATAEEAAYELASNTENVHIIAQYNPERFAEIQEQPG--DSFYVRALFDRASVDGS--------------------------------LAFHKDDILYVDNTMY-----------KGVPGQWRAWILDQDGQKLKCGFIPSKYKAEEEL--------------LMKRSLLDLEEGGTGRRGSTSTRRSFFRRRRHQQRSREDGKELAS--FSDVSINNSCGGSAGTLAEDVPPTYLRVDRL----NYP----SLRPVILVGPLQEAVVDKLEQDFPQQFQRCPSQPLRGSLQALEQGLQDLSLLDFRRRGSHYECLTLDALRHCTNHKLCHALLDVSLSAVERLNRCQIYPIVIFIKFKTTKQIREVK 1582
[Close]
BLAST of Disks large-like protein 5 vs. TrEMBL
Match: A0A131XKU3 (Putative membrane-associated guanylate kinase maguk OS=Hyalomma excavatum OX=257692 PE=2 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 3.448e-18
Identity = 136/584 (23.29%), Postives = 222/584 (38.01%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNS-----TKLKEGVVCHL--KTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHI--PTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYM-------------IEQSPNSTS-----------------KLNNCTIH---HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLR 3902
            IF+ ++  NSIA  A L  GD+++      V  +   +A      N L+  R   ++L+  QFNP K  E+  + N+   + N P                 +   + S ++   + S  + ++N + P+S     T+ K+  V     +   R V +   +    I ++GG++VGIFV + V +DS +      S    L  GDQILE NG +  +   + A   L + +    +   YNP     I   P   + FY+K  F  + +D S                                L+F KDDIL VD+T+            K  P  W AW++D+  +K++ G IPS +  E  L               MK SL               +  S   +    +        L    FS +S  N       TL+ D P   +   +     + P    S RP++L+GP  +     L    PQ++              +EQ     S                  L  CT H   H +  +S   +  L++ +I+PIVI + +K+ KQIR+++
Sbjct: 1219 IFVSSVSENSIAAQASLQVGDQLLE-----VCGINMRNATYQLAANVLRQCRDSITMLV--QFNPDKYREVASD-NISTSEENSP-----------------VDTPAASPKMRHSKRSDLIRISNDDVPSSATSTLTRQKQSCVSAKGSRAEPRIVLLRKASPSLGITLLGGNAVGIFV-HSVQEDSPA------SGPGGLLPGDQILEYNGTDLRNATAEEAAYELASNTENVHIVAQYNPERFAEIQEQPG--DSFYVKALFDRASIDGS--------------------------------LAFHKDDILYVDNTMY-----------KGVPGQWRAWILDQDGQKLKCGFIPSKYKAEEEL--------------LMKRSLLDLEEGGTGRRGSTSTRRSFFRRRRHQQRSREDGKELAS--FSDVSINNSCGGSAGTLAEDVPPTYLRVDRL----NYP----SLRPVILVGPLQEAVVDKLEQDFPQQFQRCPSQPLRGSLQALEQGLQDLSLLDFRRRGSHYECLTLDALRYCTNHKLCHALLDVSLSAVERLNRCQIFPIVIFIKFKTTKQIREVK 1701
[Close]
BLAST of Disks large-like protein 5 vs. TrEMBL
Match: L7MHS8 (Putative discs large log 5a (Fragment) OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 1.625e-17
Identity = 135/584 (23.12%), Postives = 222/584 (38.01%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNS-----TKLKEGVVCHL--KTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHI--PTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYM-------------IEQSPNSTS-----------------KLNNCTIH---HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLR 3902
            IF+ ++  NSIA  A L  GD+++      V  +   +A      N L+  R   ++L+  QFNP K  E+  + N+   + N P                 +   + S ++   + S  + ++N + P+S     T+ K+  V     +   R V +   +    I ++GG++VGIFV + V +DS +      S    L  GDQILE NG +  +   + A   L + +    +   YNP     I   P   + FY+K  F  + +D S                                L+F KDDIL VD+T+            K  P  W AW++D+  +K++ G IPS +  E  L               MK SL               +  S   +    +        L    FS +S  N       TL+ D P   +   +     + P    S RP++L+GP  +     L    PQ++              +E+     S                  L  CT H   H +  +S   +  L++ +I+PIVI + +K+ KQIR+++
Sbjct: 1152 IFVSSVSENSIAAQASLQVGDQLLE-----VCGINMRNATYQLAANVLRQCRDSITMLV--QFNPDKYREVASD-NISTSEENSP-----------------VDTPAASPKMRHSKRSDLIRISNDDVPSSATSTLTRQKQSCVSAKGSRAEPRIVLLRKASPSLGITLLGGNAVGIFV-HSVQEDSPA------SGPGGLLPGDQILEYNGTDLRNATAEEAAYELASNTENVHIIAQYNPERFAEIQEQPG--DSFYVKALFDRASIDGS--------------------------------LAFHKDDILYVDNTMY-----------KGVPGQWRAWILDQDGQKLKCGFIPSKYKAEEEL--------------LMKRSLLDLEEGGTGRRGSTSTRRSFFRRRRHQQRSREDGKELAS--FSDVSINNSCGGSAGTLAEDVPPTYLRVDRL----NYP----SLRPVILVGPLQEAVVDKLEQDFPQQFQRCPSQPLRGSLQALEKGLQDLSLLDFRRRGSHFECLTLDSLRYCTNHKLCHALLDVSLSAVERLNRCQIFPIVIFIKFKTTKQIREVK 1634
[Close]
BLAST of Disks large-like protein 5 vs. TrEMBL
Match: L7M707 (Putative discs large log 5a OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 1.916e-17
Identity = 135/584 (23.12%), Postives = 222/584 (38.01%), Query Frame = 3 
Query: 2277 IFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNS-----TKLKEGVVCHL--KTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHI--PTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYM-------------IEQSPNSTS-----------------KLNNCTIH---HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLR 3902
            IF+ ++  NSIA  A L  GD+++      V  +   +A      N L+  R   ++L+  QFNP K  E+  + N+   + N P                 +   + S ++   + S  + ++N + P+S     T+ K+  V     +   R V +   +    I ++GG++VGIFV + V +DS +      S    L  GDQILE NG +  +   + A   L + +    +   YNP     I   P   + FY+K  F  + +D S                                L+F KDDIL VD+T+            K  P  W AW++D+  +K++ G IPS +  E  L               MK SL               +  S   +    +        L    FS +S  N       TL+ D P   +   +     + P    S RP++L+GP  +     L    PQ++              +E+     S                  L  CT H   H +  +S   +  L++ +I+PIVI + +K+ KQIR+++
Sbjct: 1219 IFVSSVSENSIAAQASLQVGDQLLE-----VCGINMRNATYQLAANVLRQCRDSITMLV--QFNPDKYREVASD-NISTSEENSP-----------------VDTPAASPKMRHSKRSDLIRISNDDVPSSATSTLTRQKQSCVSAKGSRAEPRIVLLRKASPSLGITLLGGNAVGIFV-HSVQEDSPA------SGPGGLLPGDQILEYNGTDLRNATAEEAAYELASNTENVHIIAQYNPERFAEIQEQPG--DSFYVKALFDRASIDGS--------------------------------LAFHKDDILYVDNTMY-----------KGVPGQWRAWILDQDGQKLKCGFIPSKYKAEEEL--------------LMKRSLLDLEEGGTGRRGSTSTRRSFFRRRRHQQRSREDGKELAS--FSDVSINNSCGGSAGTLAEDVPPTYLRVDRL----NYP----SLRPVILVGPLQEAVVDKLEQDFPQQFQRCPSQPLRGSLQALEKGLQDLSLLDFRRRGSHFECLTLDSLRYCTNHKLCHALLDVSLSAVERLNRCQIFPIVIFIKFKTTKQIREVK 1701
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BLAST of Disks large-like protein 5 vs. Ensembl Cavefish
Match: dlg5b.1 (discs, large homolog 5b (Drosophila), tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-120206-4])

HSP 1 Score: 58.5362 bits (140), Expect = 3.488e-8
Identity = 64/308 (20.78%), Postives = 126/308 (40.91%), Query Frame = 3 
Query: 3264 YWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNC---------------TIHHIITVISKE----------FLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            YW AW +D   +K+  G +PS + +++         +FP   +C         S    +      S ++       KL H    S   K        + I T +++  +    + +++   ++     ++++RP+++LGP  +    ML    P +Y      +++ S  +  + + +C               T+  I  +I K+           +  LH   IYPIVI + YK+ KQI++ +     + KV++    + F   +  E  +S    G +    +S+ C  ++  VE  Q+E +WLP
Sbjct:  178 YWLAWQLDENAQKLARGQVPSKYMMDQ---------EFP--RRC---------SVTEGKDDGKTVSAAARRSFFRRKLKHRRSGSRDGK---DAPAPDSISTDSITYTEECLNLAYQRVQKVE-----STNRRPVLVLGPLVEPIKDMLVREAPGKYCRCLLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEIIEKDCHCLIEIAPHAIERLHTVSIYPIVIFIRYKNAKQIKEQKDPVYLRDKVSQKHSKEQFEAAQKMEQEYSKYFTGVVQGGPLSSICTQVMAIVEQEQNEPLWLP 457
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BLAST of Disks large-like protein 5 vs. Ensembl Cavefish
Match: dlg5a (discs, large homolog 5a (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-3149])

HSP 1 Score: 51.2174 bits (121), Expect = 9.330e-6
Identity = 30/102 (29.41%), Postives = 50/102 (49.02%), Query Frame = 3 
Query: 3789 HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            H +  I+   +  LH   IYPIVI + YK+ KQI++L+     + KV++    + F   +  E  +S    G +    +   C  IV  V+  QS+ +W P+
Sbjct: 1702 HCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKELKDPVYLRDKVSQKHSKEQFEGAQKIEQEYSKFFTGIVQGGTLPYICTQIVTIVDQEQSKVLWTPL 1803
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BLAST of Disks large-like protein 5 vs. Ensembl Cavefish
Match: dlg5a (discs, large homolog 5a (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-3149])

HSP 1 Score: 51.2174 bits (121), Expect = 9.334e-6
Identity = 41/180 (22.78%), Postives = 72/180 (40.00%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKP----------------------QEYMIEQSPNSTSKLNNCTIH----------HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            +S RP+++LGP  D    ML    P                      ++++       +   +  T+           H +  I+   +  LH   IYPIVI + YK+ KQI++L+     + KV++    + F   +  E  +S    G +    +   C  IV  V+  QS+ +W P+
Sbjct: 1763 TSPRPVLILGPLVDPVKDMLVKESPGKFSRCVLEVMKASQQAIERGVKDFLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKELKDPVYLRDKVSQKHSKEQFEGAQKIEQEYSKFFTGIVQGGTLPYICTQIVTIVDQEQSKVLWTPL 1942
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BLAST of Disks large-like protein 5 vs. Ensembl Nematostella
Match: EDO41849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S398])

HSP 1 Score: 50.0618 bits (118), Expect = 7.767e-6
Identity = 44/187 (23.53%), Postives = 76/187 (40.64%), Query Frame = 3 
Query: 3660 RPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTI--------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCV----AIVEKVETIQSEDIWLPVDQFEYSE*VECNYELFTRSFTSNL 4166
            RP+VLLGP +D     L   +P  Y +  +  ST    N                  H +  I+ + +  L+  ++YPIVI ++ K    I++LR     Q K +     K+F      +  ++H+   S+         +     + +K+  +Q  ++W    +FE  E VE N       + SNL
Sbjct:  262 RPVVLLGPLADIAIDKLLMDQPHVYAVPTAFGSTPGGKNARRTLSYAAIKEVVDKHQHCLLDIAPDEVERLNYCQLYPIVIHIDVKDKNAIKELRTS-MGQSKESAKHIKKLFDDEAKLKKKYTHLFTTSVTAGTEPELKLKWMNELKDKIRDLQDGNVWASETEFEEHEGVEFNRRSMAFDYESNL 447
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BLAST of Disks large-like protein 5 vs. Ensembl Medaka
Match: ENSORLT00000039944.1 (discs large MAGUK scaffold protein 5 [Source:NCBI gene;Acc:101171446])

HSP 1 Score: 52.373 bits (124), Expect = 4.417e-6
Identity = 40/178 (22.47%), Postives = 74/178 (41.57%), Query Frame = 3 
Query: 3654 SKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            S RP+++LGP  +T   ML    P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYP+V+ + YK+ KQI++ +     + K+++    + F   +  E  +S    G +    VS  C  I   VE  QS+ +W+P
Sbjct: 1756 SPRPVLILGPLVETVKDMLVKETPAKFCRCLPEIMKASQQAIERGVKDCVFIDFKRRSGHFDVTTVASIKEITEKDSHCLLDIAPHAIERLHSVHIYPVVLFIRYKNAKQIKEQKDPLYLREKLSQKHSKEQFELSQKIEQDYSRFFTGVIQGGSVSYMCTQITTMVEQEQSKVLWIP 1933
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BLAST of Disks large-like protein 5 vs. Ensembl Medaka
Match: ENSORLT00000011096.2 (discs large MAGUK scaffold protein 5 [Source:NCBI gene;Acc:101171446])

HSP 1 Score: 52.373 bits (124), Expect = 4.500e-6
Identity = 40/178 (22.47%), Postives = 74/178 (41.57%), Query Frame = 3 
Query: 3654 SKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI-------------------------HHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLP 4091
            S RP+++LGP  +T   ML    P ++      +++ S  +  + + +C                            H +  I+   +  LH   IYP+V+ + YK+ KQI++ +     + K+++    + F   +  E  +S    G +    VS  C  I   VE  QS+ +W+P
Sbjct: 1786 SPRPVLILGPLVETVKDMLVKETPAKFCRCLPEIMKASQQAIERGVKDCVFIDFKRRSGHFDVTTVASIKEITEKDSHCLLDIAPHAIERLHSVHIYPVVLFIRYKNAKQIKEQKDPLYLREKLSQKHSKEQFELSQKIEQDYSRFFTGVIQGGSVSYMCTQITTMVEQEQSKVLWIP 1963
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BLAST of Disks large-like protein 5 vs. Ensembl Medaka
Match: dlg5a (disks large homolog 5 [Source:NCBI gene;Acc:101174943])

HSP 1 Score: 51.2174 bits (121), Expect = 9.315e-6
Identity = 41/180 (22.78%), Postives = 77/180 (42.78%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI--------H-----------------HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            +S RP+++LGP SD    ML    P ++      +++ S  +  + + +C          H                 H +  I+   +  LH  +IYPIV+ + YK+ KQI++ +     + KV++    + F   +  E  +S    G +    +   C  I+  V+  QS+ +W P+
Sbjct: 1837 TSPRPVLILGPLSDPVKEMLMKESPGKFCRCVLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITDKGCHCLLEIAPHAIERLHSVQIYPIVVFIRYKNAKQIKEQKDPIYLRDKVSQKHSKEQFECAQKIEQEYSKFFTGIVQGGTLPYICTQIITIVDQEQSKVLWTPL 2016
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BLAST of Disks large-like protein 5 vs. Ensembl Medaka
Match: dlg5a (disks large homolog 5 [Source:NCBI gene;Acc:101174943])

HSP 1 Score: 51.2174 bits (121), Expect = 9.552e-6
Identity = 41/180 (22.78%), Postives = 77/180 (42.78%), Query Frame = 3 
Query: 3651 SSKRPLVLLGPHSDTFAMMLASTKPQEY------MIEQSPNSTSK-LNNCTI--------H-----------------HIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPV 4094
            +S RP+++LGP SD    ML    P ++      +++ S  +  + + +C          H                 H +  I+   +  LH  +IYPIV+ + YK+ KQI++ +     + KV++    + F   +  E  +S    G +    +   C  I+  V+  QS+ +W P+
Sbjct: 1834 TSPRPVLILGPLSDPVKEMLMKESPGKFCRCVLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITDKGCHCLLEIAPHAIERLHSVQIYPIVVFIRYKNAKQIKEQKDPIYLRDKVSQKHSKEQFECAQKIEQEYSKFFTGIVQGGTLPYICTQIITIVDQEQSKVLWTPL 2013
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BLAST of Disks large-like protein 5 vs. Planmine SMEST
Match: SMESG000059889.1 (SMESG000059889.1)

HSP 1 Score: 2476.05 bits (6416), Expect = 0.000e+0
Identity = 1327/1347 (98.52%), Postives = 1333/1347 (98.96%), Query Frame = 3 
Query:   78 MDRLXXXXXXXXXSFDGNF-ENFNMTSDDACNHNNSINTARTIPFNYTNSGNPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHEYSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVMQERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENGLYYNQLQGVLNENDTLKSKMANLESTIEELKSHNEMSCMQLNCVLDKYHKLKMAVANDVNHDRDFNSWINTPLIMRSISGTVVNEKIVTGSVKMIDLKMMLLKISYDGTCRTDSTIINKNDCDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWSVNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTPLWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDPSSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDSDCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLXXXXXXXXXXXXXXXXXXLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQSAIQFNFHNSMNATRRELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSKIFCXXXXXXXXXXXXTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE 4115
            MD+LNNNNNDNYNSFDGNF ENFNMTSDD CNHNNSINTARTIPFNYTNSGNPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHEYSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVMQERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENG+YYNQLQGVLNENDTLKS+MANLESTIEELKSHNEMSCMQLNCVLDKYHKLKMAVANDVNHDRDF          +SISGTVVNEKIVTGSVKMIDLKMMLLKISYDGTCRTDSTIINKNDCDNLLNSNSSNGAAAA +AVASINDGDDDYDDDAAAAVVGGGGGSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWSVNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTPLWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDPSSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDSDCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLSNISVSSAPPVPPRSSTSLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQSAIQFNFHNSMNAT RELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSKIFCLKDLGLHLLHGKTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPS+RFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCSTPSSPISETTEFLSSPSSSFQNDSSKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE
Sbjct:    1 MDKLNNNNNDNYNSFDGNFFENFNMTSDDVCNHNNSINTARTIPFNYTNSGNPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHEYSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVMQERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENGVYYNQLQGVLNENDTLKSEMANLESTIEELKSHNEMSCMQLNCVLDKYHKLKMAVANDVNHDRDF----------KSISGTVVNEKIVTGSVKMIDLKMMLLKISYDGTCRTDSTIINKNDCDNLLNSNSSNGAAAASAAVASINDGDDDYDDDAAAAVVGGGGGSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWSVNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTPLWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDPSSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDSDCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLSNISVSSAPPVPPRSSTSLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQSAIQFNFHNSMNATSRELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSKIFCLKDLGLHLLHGKTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSMRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCSTPSSPISETTEFLSSPSSSFQNDSSKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE 1337
[Close]
BLAST of Disks large-like protein 5 vs. Planmine SMEST
Match: SMESG000059889.1 (SMESG000059889.1)

HSP 1 Score: 2457.17 bits (6367), Expect = 0.000e+0
Identity = 1305/1323 (98.64%), Postives = 1310/1323 (99.02%), Query Frame = 3 
Query:  147 MTSDDACNHNNSINTARTIPFNYTNSGNPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHEYSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVMQERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENGLYYNQLQGVLNENDTLKSKMANLESTIEELKSHNEMSCMQLNCVLDKYHKLKMAVANDVNHDRDFNSWINTPLIMRSISGTVVNEKIVTGSVKMIDLKMMLLKISYDGTCRTDSTIINKNDCDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWSVNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTPLWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDPSSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDSDCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLXXXXXXXXXXXXXXXXXXLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQSAIQFNFHNSMNATRRELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSKIFCXXXXXXXXXXXXTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCXXXXXXXXXXXXFLXXXXXXXXXXXXKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE 4115
            MTSDD CNHNNSINTARTIPFNYTNSGNPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHEYSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVMQERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENG+YYNQLQGVLNENDTLKS+MANLESTIEELKSHNEMSCMQLNCVLDKYHKLKMAVANDVNHDRDF          +SISGTVVNEKIVTGSVKMIDLKMMLLKISYDGTCRTDSTIINKNDCDNLLNSNSSNGAAAA +AVASINDGDDDYDDDAAAAVVGGGGGSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWSVNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTPLWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDPSSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDSDCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLSNISVSSAPPVPPRSSTSLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQSAIQFNFHNSMNAT RELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSKIFCLKDLGLHLLHGKTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPS+RFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCSTPSSPISETTEFLSSPSSSFQNDSSKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE
Sbjct:    1 MTSDDVCNHNNSINTARTIPFNYTNSGNPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHEYSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVMQERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENGVYYNQLQGVLNENDTLKSEMANLESTIEELKSHNEMSCMQLNCVLDKYHKLKMAVANDVNHDRDF----------KSISGTVVNEKIVTGSVKMIDLKMMLLKISYDGTCRTDSTIINKNDCDNLLNSNSSNGAAAASAAVASINDGDDDYDDDAAAAVVGGGGGSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWSVNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTPLWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDPSSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDSDCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLSNISVSSAPPVPPRSSTSLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQSAIQFNFHNSMNATSRELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSKIFCLKDLGLHLLHGKTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGLVEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLKMHELFKEKNLLPFDPNIPSMRFTRSMYDDTNFTRGIHDNSLSHRLHIIRSSSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSSVGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAVSTLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLTSFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASMTKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKFPISEKCMKYSLCSTPSSPISETTEFLSSPSSSFQNDSSKLFHTHHSSLGQKIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLLGPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSELHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYESSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE 1313
The following BLAST results are available for this feature:
BLAST of Disks large-like protein 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
DLG57.828e-622.35discs large MAGUK scaffold protein 5 [Source:HGNC ... [more]
DLG57.828e-622.35discs large MAGUK scaffold protein 5 [Source:HGNC ... [more]
DLG59.116e-621.53discs large MAGUK scaffold protein 5 [Source:HGNC ... [more]
DLG59.116e-621.53discs large MAGUK scaffold protein 5 [Source:HGNC ... [more]
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BLAST of Disks large-like protein 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
zoo-11.055e-722.52ZO-1 (Zonula Occludens tight junctional protein) O... [more]
zoo-11.185e-722.52ZO-1 (Zonula Occludens tight junctional protein) O... [more]
zoo-11.244e-722.52ZO-1 (Zonula Occludens tight junctional protein) O... [more]
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BLAST of Disks large-like protein 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Dlg55.442e-729.13gene:FBgn0032363 transcript:FBtr0336631[more]
Dlg55.442e-729.13gene:FBgn0032363 transcript:FBtr0080246[more]
Dlg55.442e-729.13gene:FBgn0032363 transcript:FBtr0080247[more]
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BLAST of Disks large-like protein 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dlg5a2.981e-1422.10discs, large homolog 5a (Drosophila) [Source:ZFIN;... [more]
dlg5a3.794e-1422.10discs, large homolog 5a (Drosophila) [Source:ZFIN;... [more]
dlg5b.11.047e-622.78discs, large homolog 5b (Drosophila), tandem dupli... [more]
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BLAST of Disks large-like protein 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Disks large-like protein 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Dlg52.671e-623.46discs large MAGUK scaffold protein 5 [Source:MGI S... [more]
Dlg52.712e-623.46discs large MAGUK scaffold protein 5 [Source:MGI S... [more]
Dlg53.519e-623.46discs large MAGUK scaffold protein 5 [Source:MGI S... [more]
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BLAST of Disks large-like protein 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Disks large-like protein 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A023GKY78.440e-2123.70Putative membrane-associated guanylate kinase magu... [more]
A0A1E1XBJ22.439e-1823.29Putative membrane-associated guanylate kinase magu... [more]
A0A131XKU33.448e-1823.29Putative membrane-associated guanylate kinase magu... [more]
L7MHS81.625e-1723.12Putative discs large log 5a (Fragment) OS=Rhipicep... [more]
L7M7071.916e-1723.12Putative discs large log 5a OS=Rhipicephalus pulch... [more]
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BLAST of Disks large-like protein 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dlg5b.13.488e-820.78discs, large homolog 5b (Drosophila), tandem dupli... [more]
dlg5a9.330e-629.41discs, large homolog 5a (Drosophila) [Source:ZFIN;... [more]
dlg5a9.334e-622.78discs, large homolog 5a (Drosophila) [Source:ZFIN;... [more]
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BLAST of Disks large-like protein 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Disks large-like protein 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Disks large-like protein 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO418497.767e-623.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Disks large-like protein 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSORLT00000039944.14.417e-622.47discs large MAGUK scaffold protein 5 [Source:NCBI ... [more]
ENSORLT00000011096.24.500e-622.47discs large MAGUK scaffold protein 5 [Source:NCBI ... [more]
dlg5a9.315e-622.78disks large homolog 5 [Source:NCBI gene;Acc:101174... [more]
dlg5a9.552e-622.78disks large homolog 5 [Source:NCBI gene;Acc:101174... [more]
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BLAST of Disks large-like protein 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000059889.10.000e+098.52SMESG000059889.1[more]
SMESG000059889.10.000e+098.64SMESG000059889.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011728 ID=SMED30011728|Name=Disks large-like protein 5|organism=Schmidtea mediterranea sexual|type=transcript|length=4195bp
TTGATGTGGTTTATGCGATGCAAGTTTTTTCCCGAATGTTTACAAATTTT
TACAAAACATGATGTGTTCATTTCACAATGGATAGGTTAAACAATAACAA
TAATGACAATTATAATTCTTTTGATGGTAATTTTGAAAATTTTAATATGA
CATCTGATGATGCCTGTAATCACAATAACTCAATCAATACAGCAAGAACA
ATTCCATTCAACTATACTAATAGTGGAAATCCAATTTCATCATTGAACTC
ACAAGAGTTTACCAGAGCGAATTTTGATCGAATGAAAGATCGTCAGATAT
CTATATTAACCCAGAAAAATAATATTCTAGAAACTGAGTTATTGGCAATG
CGTCAGAAATATCCAGTATTGCATGAATATTCAATGATGGGGCATTTAAG
TAATGGAAACAAACATCTATATTTACAGATTAAATTATTGTCGACTACTC
TCAATGAAAAGTTTGAAGAATTACGGCAAACCAAAGAAGAATTGCGTCAA
ACAAAAAAGGAGTATAAATTAGTCATGCAAGAACGAACCACTGTCCATCG
GGAATTACAAGAACAAACGGCAGAGATAGAAATGTTAAAGAACCAAGTGC
AAATTTTAGAGGAGCAATTAAATTTCAAAACATCACCCAAGTCAAATGGG
ATATTGGACACAGAAAATGGGCTTTATTACAATCAACTGCAAGGAGTGCT
GAATGAGAATGATACCCTCAAATCCAAAATGGCCAACCTAGAATCAACCA
TTGAAGAACTGAAATCCCACAATGAAATGAGCTGCATGCAATTGAATTGT
GTATTGGATAAATATCATAAGCTAAAAATGGCTGTAGCTAATGATGTCAA
CCATGATAGGGATTTCAATTCTTGGATAAATACTCCTCTCATAATGCGAT
CCATATCCGGAACGGTGGTAAATGAAAAAATAGTCACTGGCAGCGTGAAA
ATGATTGATTTGAAAATGATGCTTTTGAAAATTTCATATGATGGAACTTG
TAGAACCGATTCTACGATAATCAATAAGAACGACTGTGATAATTTATTGA
ACTCTAATAGTAGCAATGGTGCTGCTGCTGCCATCTCTGCTGTAGCGTCA
ATAAATGATGGTGATGACGATTATGATGATGATGCTGCTGCTGCTGTTGT
TGGCGGCGGCGGCGGCAGCATCAATTCTTCGTGGAAGGCGGCGGACTGTA
GTTTTGATGAAACAATCTGTCTCCGAGAAGGTGACCAATTGTTGAAAATT
GAAGGTACGGATGTGGCTAATTGGTCTGTGAATAAAATCGTGGAATTTCT
GAGTAGGTTTGAGGCCAGCTCTTATTTGAAAATTGTAATATTGCGAACAT
CTCTTAAATCTGGACGTTATATGTCGTGGAAAGTAAAATTGGATACTTCT
ATGGTAAACAGTCTCTGTCTCACTCCTTTGTGGATGGTTTCGGTCTCTGA
TTTCAATGACAAAGATTTGCTTGTGTTTAAATCGGGAGATATTTTGCAAT
TGAAAAGCGACAATTGCAAAACCAAGACCAATTCTATTCAATCTAAAATG
GCGGTGAAAATTATCCGTTTGGATCCGTCATCGTTGGTAACAAACGATAA
AGAATCCGAAGATCAACAGAAAATTTCTCAATATCTTTCCCCCGTTACTT
ACAGAACTACTAATCATGTACAAAATACATATTCGAATTCAAAATATGGG
TCTGTTGGGTCTCCTGACTTGGATTCTGATTGTTTATTGACGGGTCAATC
ATTATTCCCAGTGTTACCAGTAAAACAGAAACTTCACGTTTTCTCTGACA
CTTATTCTAAGTCCTCTCATAGACCAATATCCGACTACAATTTATCTCAA
CTTAGCAATATATCAGTTTCGTCAGCGCCCCCAGTGCCACCAAGGTCCAG
TACAAGTCTTCAGTATTCTTTCATGGAAAACATTGACCATCCGAATGTGC
TTCACGTCAATAATGACAGTGTGGGAAACCGAGGATTTGATATGAAGGAC
AGTGAAAAATTGAATTTGTCTGTTCAATCGGCTATTCAATTCAATTTTCA
CAATAGTATGAATGCCACACGTCGGGAGTTGATGTCAGCTTCATTCAATT
GCACCAGTGAATTCTCCACCCATAAAATACCGAAATTGGGCAAATGTCGG
AAAGTTACTTTGACGGTGCCATCGAAAATATTTTGTCTGAAAGATTTGGG
ATTGCATTTATTGCATGGTAAAACAGAAGAAGCTCCTGTGAGCAAGTCAG
ATGTGGATGTGTCTGTGATCAATCAAATTTTCATTCGCACTATTGACTTT
AATAGTATTGCACATTCGGCTGGTCTAGTGGAGGGGGATGAAATCATAAC
AATTAATAATCATCCCGTGAGTAAAATGACTTCAGAGGACGCCGAAAATG
CATTCTTAACCAACCCATTGAAACCAGACCGACAGAAATATTCTCTTCTC
ATTAAAGCTCAATTTAATCCTTTAAAAATGCACGAACTTTTCAAAGAGAA
AAATCTTTTGCCATTTGATCCAAATATCCCTTCGGTGCGATTTACTAGAA
GTATGTATGATGACACGAATTTCACCCGAGGAATTCATGATAATAGTCTT
TCACATCGGCTTCATATTATTCGAAGTTCCTCTAATCTCAATGTGACAAA
CACAGAAGAACCTAATTCAACCAAATTAAAAGAAGGAGTTGTTTGTCATT
TAAAAACTCATTTTAGAACTGTCAGAATCAATATTTATACCGTTCTTAAA
TTAATAAAAATCATTGGTGGTTCGAGTGTTGGGATATTTGTGTCAAATGT
TGTGTATAAAGATTCTAACTCGGAAATAAACGATAAGGAGAGTATTGGAA
ACAGATTAGCTATTGGTGATCAAATTTTAGAGGTAAATGGAGAAAACTTC
GAGCATGTGATCGGTGATATGGCAGTGTCGACTTTGAACAATTTATCTCA
TCAAACCGTTTTGAAAGTTCTTTACAATCCTTCAGGATTGCTAACCATCA
ACAGTGATCCATTCTGTCAGGAAAGGTTTTACATGAAGACGACATTTTCA
TTCTCCGAATTAGACAATTCTTTAACGTCATTTTCTGGAAAAAGAGAAAA
GGCAGCATCCGTTTGTTCACGATTGGATCATTTGGTTGTGAACATTCAAT
TTCTAAGAAATTTTCATTTAAGCTTTGAGAAAGATGATATATTATTAGTG
GATTCGACCATTCTTCCGGCTTCCATGACAAAACCTAATCAATCCGATAA
AAACACTCCAACTTATTGGCATGCTTGGGTGGTTGACAGACAAAATAAAA
AAATCAGAAGTGGGATGATTCCCTCTGCATTTTGGATTGAAAGAATGTTA
TCAATTCATTTGAAATCTTTCAAATTTCCGATTTCAGAAAAATGCATGAA
ATATTCTTTGTGTTCAACTCCCAGTTCTCCGATTTCGGAAACCACAGAAT
TTCTATCTAGTCCCAGTAGCAGCTTTCAAAATGACTCATCGAAGTTATTT
CATACACATCATTCTAGTCTTGGGCAAAAAATCTTCAGTCGCATCTCTTT
CAAAAATCATATTCCAACGAAAACACTATCTAGTGATGATCCGAATAAAG
GAATCCATTTCAAAAAATTTGTTCCGATTAAACATTTACCAAGAGTCACC
AGTTCGAAACGACCTCTTGTCCTCCTGGGACCACATTCAGACACATTTGC
CATGATGTTGGCAAGCACGAAGCCTCAGGAGTATATGATCGAACAGTCTC
CAAATTCCACGAGCAAATTGAATAATTGTACAATTCATCATATAATTACT
GTTATATCCAAAGAATTTCTCTCAGAATTACATCAAAATAAAATATATCC
AATTGTTATACTACTCAATTATAAATCCCCCAAACAAATCAGGCAATTGA
GAATTTGTAAGACATCTCAAATCAAAGTTAATAAATCAGATTGCAATAAA
ATGTTTACTCAGCTAAAGGACTATGAAAGCAGTTGGTCACATATTATACA
TGGTTCCCTATTTCCAAGTCATGTATCCAACACTTGTGTAGCTATTGTTG
AAAAGGTTGAAACTATCCAGTCAGAGGATATTTGGTTGCCTGTTGATCAG
TTTGAGTATTCGGAATGAGTTGAATGTAATTATGAGCTATTTACGCGTTC
TTTCACATCCAATTTATTTAAATAAATTGTTTTGACATAGCTGGT
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protein sequence of SMED30011728-orf-1

>SMED30011728-orf-1 ID=SMED30011728-orf-1|Name=SMED30011728-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1347bp
MDRLNNNNNDNYNSFDGNFENFNMTSDDACNHNNSINTARTIPFNYTNSG
NPISSLNSQEFTRANFDRMKDRQISILTQKNNILETELLAMRQKYPVLHE
YSMMGHLSNGNKHLYLQIKLLSTTLNEKFEELRQTKEELRQTKKEYKLVM
QERTTVHRELQEQTAEIEMLKNQVQILEEQLNFKTSPKSNGILDTENGLY
YNQLQGVLNENDTLKSKMANLESTIEELKSHNEMSCMQLNCVLDKYHKLK
MAVANDVNHDRDFNSWINTPLIMRSISGTVVNEKIVTGSVKMIDLKMMLL
KISYDGTCRTDSTIINKNDCDNLLNSNSSNGAAAAISAVASINDGDDDYD
DDAAAAVVGGGGGSINSSWKAADCSFDETICLREGDQLLKIEGTDVANWS
VNKIVEFLSRFEASSYLKIVILRTSLKSGRYMSWKVKLDTSMVNSLCLTP
LWMVSVSDFNDKDLLVFKSGDILQLKSDNCKTKTNSIQSKMAVKIIRLDP
SSLVTNDKESEDQQKISQYLSPVTYRTTNHVQNTYSNSKYGSVGSPDLDS
DCLLTGQSLFPVLPVKQKLHVFSDTYSKSSHRPISDYNLSQLSNISVSSA
PPVPPRSSTSLQYSFMENIDHPNVLHVNNDSVGNRGFDMKDSEKLNLSVQ
SAIQFNFHNSMNATRRELMSASFNCTSEFSTHKIPKLGKCRKVTLTVPSK
IFCLKDLGLHLLHGKTEEAPVSKSDVDVSVINQIFIRTIDFNSIAHSAGL
VEGDEIITINNHPVSKMTSEDAENAFLTNPLKPDRQKYSLLIKAQFNPLK
MHELFKEKNLLPFDPNIPSVRFTRSMYDDTNFTRGIHDNSLSHRLHIIRS
SSNLNVTNTEEPNSTKLKEGVVCHLKTHFRTVRINIYTVLKLIKIIGGSS
VGIFVSNVVYKDSNSEINDKESIGNRLAIGDQILEVNGENFEHVIGDMAV
STLNNLSHQTVLKVLYNPSGLLTINSDPFCQERFYMKTTFSFSELDNSLT
SFSGKREKAASVCSRLDHLVVNIQFLRNFHLSFEKDDILLVDSTILPASM
TKPNQSDKNTPTYWHAWVVDRQNKKIRSGMIPSAFWIERMLSIHLKSFKF
PISEKCMKYSLCSTPSSPISETTEFLSSPSSSFQNDSSKLFHTHHSSLGQ
KIFSRISFKNHIPTKTLSSDDPNKGIHFKKFVPIKHLPRVTSSKRPLVLL
GPHSDTFAMMLASTKPQEYMIEQSPNSTSKLNNCTIHHIITVISKEFLSE
LHQNKIYPIVILLNYKSPKQIRQLRICKTSQIKVNKSDCNKMFTQLKDYE
SSWSHIIHGSLFPSHVSNTCVAIVEKVETIQSEDIWLPVDQFEYSE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036034PDZ_sf
IPR001478PDZ
IPR027417P-loop_NTPase
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0042981regulation of apoptotic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 205..232
NoneNo IPR availableCOILSCoilCoilcoord: 119..181
NoneNo IPR availableCOILSCoilCoilcoord: 75..95
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1189..1342
e-value: 1.5E-14
score: 56.0
NoneNo IPR availablePANTHERPTHR46360FAMILY NOT NAMEDcoord: 790..994
coord: 1238..1341
coord: 1031..1093
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 881..966
e-value: 3.64275E-7
score: 47.1763
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 692..773
e-value: 2.4181E-9
score: 53.3395
IPR001478PDZ domainSMARTSM00228pdz_newcoord: 706..797
e-value: 0.0032
score: 26.7
coord: 890..969
e-value: 0.12
score: 21.4
coord: 360..426
e-value: 4.4
score: 6.6
IPR001478PDZ domainPFAMPF00595PDZcoord: 728..776
e-value: 1.2E-5
score: 25.6
IPR001478PDZ domainPROSITEPS50106PDZcoord: 693..773
score: 9.752
IPR001478PDZ domainPROSITEPS50106PDZcoord: 890..969
score: 10.295
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 357..440
e-value: 3.7E-5
score: 25.3
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 891..977
e-value: 6.3E-9
score: 37.5
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 675..799
e-value: 1.7E-8
score: 36.3
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 383..441
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 894..971
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 729..777