1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30011684 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 24
Homology
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Human
Match: PLCB4 (phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]) HSP 1 Score: 1247.65 bits (3227), Expect = 0.000e+0 Identity = 641/1169 (54.83%), Postives = 838/1169 (71.69%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLE----MFLKGQTE----IIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ W+SE EGQVL+ S ++ +R G+ PK+ KI A L + + N L+ RIV +CSGTDLVNIS+T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L NG IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++F++EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE M G++ I++++NE + + D E+ E +P N+ HK + VK+ SD D +KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T ++ + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNE-----EEIESADQEE----EAHPEFKFGNELSADDLGHKEAVAN--SVKKASD-------------DLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIEL-IPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1131
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Human
Match: PLCB4 (phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]) HSP 1 Score: 1247.65 bits (3227), Expect = 0.000e+0 Identity = 641/1169 (54.83%), Postives = 838/1169 (71.69%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLE----MFLKGQTE----IIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ W+SE EGQVL+ S ++ +R G+ PK+ KI A L + + N L+ RIV +CSGTDLVNIS+T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L NG IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++F++EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE M G++ I++++NE + + D E+ E +P N+ HK + VK+ SD D +KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T ++ + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNE-----EEIESADQEE----EAHPEFKFGNELSADDLGHKEAVAN--SVKKASD-------------DLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIEL-IPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1131
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Human
Match: PLCB4 (phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]) HSP 1 Score: 1246.11 bits (3223), Expect = 0.000e+0 Identity = 640/1161 (55.12%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ W+SE EGQVL+ S ++ +R G+ PK+ KI A L + + N L+ RIV +CSGTDLVNIS+T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L NG IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++F++EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE + E E+A + L ED EI + + HPE E S L K ++ N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T ++ + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRS-----MMEAGESASPANIL-----EDDNEEEIES---ADQEEEAHPEFKFG--------NELSADDLGHK-------EAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Human
Match: PLCB4 (phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]) HSP 1 Score: 1246.11 bits (3223), Expect = 0.000e+0 Identity = 640/1161 (55.12%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ W+SE EGQVL+ S ++ +R G+ PK+ KI A L + + N L+ RIV +CSGTDLVNIS+T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L NG IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++F++EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE + E E+A + L ED EI + + HPE E S L K ++ N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T ++ + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRS-----MMEAGESASPANIL-----EDDNEEEIES---ADQEEEAHPEFKFG--------NELSADDLGHK-------EAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Human
Match: PLCB4 (phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]) HSP 1 Score: 1245.34 bits (3221), Expect = 0.000e+0 Identity = 640/1161 (55.12%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ W+SE EGQVL+ S ++ +R G+ PK+ KI A L + + N L+ RIV +CSGTDLVNIS+T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L NG IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++F++EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE + E E+A + L ED EI + + HPE E S L K ++ N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T ++ + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRS-----MMEAGESASPANIL-----EDDNEEEIES---ADQEEEAHPEFKFG--------NELSADDLGHK-------EAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIEL-IPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Celegans
Match: egl-8 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 [Source:UniProtKB/Swiss-Prot;Acc:G5EBH0]) HSP 1 Score: 1056.97 bits (2732), Expect = 0.000e+0 Identity = 588/1260 (46.67%), Postives = 816/1260 (64.76%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLER-ISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKS-DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQ-EPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPT-IIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGN--FPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG----KPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISH--------------------------------YNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ----EKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
+K F+FNW+ + +L++G+ FDRYD++S LE N VR+DE GFF+ W E + VLD+ Q+ + R G PK+ +I L +R S + +R + I G DLVN+ +V++ E+A + + ++++ +VCP QL K+ L + V IP++ I KTF+SGK EK++ + L +LGL K +E+D TFEKF LY+KICPRT+++E+F +LS K+++T E++I +LNE QRDPRLNEILFPF + + +L +E +Y+++GK+S + F R+LMSD+N PVFLDR+ + DMDQPL HYYINSSHNTYLTGRQ+GGKSS EIYRQVLLSGCRCIELDCWDG GE++ EPIITHGKAMCTD+ FKDV+ IRDTAF S+ P++LSFENHCSK Q K+AKYC D+ GD+LL+KP + L V LPSP +LRKKILIKNKRLK ++E+ QL+ FL+ + EE+E E P+ V GED ++P + K + + HPE+ + + LK + K+ LT EEE+ + A+YHY GATTNIHP LS++VNYT PVKF GFD+AE N+H+HMSSF+E+ GLG +++ V+YNKRQ SRIYP+G RVDS+NF+PQIFWNAGCQMV+LNFQTPD+ MQLN GKFEYNG SGYLLKP+F+RRP+R+FDPFSESP+DGVIAA +++ISGQFLSD+K+GTYVEV+MYGLPTDT RKE +T+V+P NGLNP+Y +D F+FRKVVLP+LAVLR VY++ GK +GQR+LPL+GLQ+GYRHISLR++ N F LS P +F +I TY+P+ L LVDAL+DPRA+LS+++KR + LA MG++ SDI DVP T + K+PP + +++ + G +S S+ + + + D+ K D I + L DK F KL+KR +EL++LRKKH+K + K Q DKL N+ R K+ + SL +S C + + V +++ LV T T EW++M +H +EE +L L+ + +LL K+M E Q++Q LK+ E E K++K QTK S++ K + D+ +K KAERDRR++ELN+ N K F+++RK A K + ++L ++H +Q +K+ A+D E +KE+ LA + + +
Sbjct: 2 AKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVLDMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVELAKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKMVQKCLNDLGLGGDKEREELDVDILTFEKFQRLYNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDIERHQLDQFLREGK--LDEEDELNETPE----VVGEDS----VSPREMPAKENDEAHPELKQNFIAKNLK--------------------GFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDP-FVFRKVVLPELAVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILS-PVLFVQIVIKTYVPDELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSSADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQQTNVDKLITNNRRSTKKEKGSRRSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVPQDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLALKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVG----NYKEEQLAAQPTSVV 1225
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Celegans
Match: egl-8 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 [Source:UniProtKB/Swiss-Prot;Acc:G5EBH0]) HSP 1 Score: 1049.27 bits (2712), Expect = 0.000e+0 Identity = 595/1321 (45.04%), Postives = 826/1321 (62.53%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLER-ISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKS-DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQ-EPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPT-IIVKNDTDPHPEMHKT----ELNGLLKVKEQSDTQLNI-----------------------------KVKEEKEPDSRKNASKKGS----------------------------LTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGN--FPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG----KPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISH--------------------------------YNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ----EKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
+K F+FNW+ + +L++G+ FDRYD++S LE N VR+DE GFF+ W E + VLD+ Q+ + R G PK+ +I L +R S + +R + I G DLVN+ +V++ E+A + + ++++ +VCP QL K+ L + V IP++ I KTF+SGK EK++ + L +LGL K +E+D TFEKF LY+KICPRT+++E+F +LS K+++T E++I +LNE QRDPRLNEILFPF + + +L +E +Y+++GK+S + F R+LMSD+N PVFLDR+ + DMDQPL HYYINSSHNTYLTGRQ+GGKSS EIYRQVLLSGCRCIELDCWDG GE++ EPIITHGKAMCTD+ FKDV+ IRDTAF S+ P++LSFENHCSK Q K+AKYC D+ GD+LL+KP + L V LPSP +LRKKILIKNKRLK ++E+ QL+ FL+ + EE+E E P+ V GED ++P + K + + HPE+ + L G K+Q D+ ++ + E + R KKG LT EEE+ + A+YHY GATTNIHP LS++VNYT PVKF GFD+AE N+H+HMSSF+E+ GLG +++ V+YNKRQ SRIYP+G RVDS+NF+PQIFWNAGCQMV+LNFQTPD+ MQLN GKFEYNG SGYLLKP+F+RRP+R+FDPFSESP+DGVIAA +++ISGQFLSD+K+GTYVEV+MYGLPTDT RKE +T+V+P NGLNP+Y +D F+FRKVVLP+LAVLR VY++ GK +GQR+LPL+GLQ+GYRHISLR++ N F LS P +F +I TY+P+ L LVDAL+DPRA+LS+++KR + LA MG++ SDI DVP T + K+PP + +++ + G +S S+ + + + D+ K D I + L DK F KL+KR +EL++LRKKH+K + K Q DKL N+ R K+ + SL +S C + + V +++ LV T T EW++M +H +EE +L L+ + +LL K+M E Q++Q LK+ E E K++K QTK S++ K + D+ +K KAERDRR++ELN+ N K F+++RK A K + ++L ++H +Q +K+ A+D E +KE+ LA + + +
Sbjct: 2 AKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVLDMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVELAKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKMVQKCLNDLGLGGDKEREELDVDILTFEKFQRLYNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDIERHQLDQFLREGK--LDEEDELNETPE----VVGEDS----VSPREMPAKENDEAHPELKQNFIAKNLKGFGFSKKQPDSSTSLLTASPTPSSSSMAMSNANNPFSSSTLNSPQPMERSRSEKRSFRQKKGGVFGDELHSDSAALIDFMRTASSRKKKPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDP-FVFRKVVLPELAVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILS-PVLFVQIVIKTYVPDELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSSADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQQTNVDKLITNNRRSTKKEKGSRRSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVPQDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLALKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVG----NYKEEQLAAQPTSVV 1306
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Celegans
Match: egl-8 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 [Source:UniProtKB/Swiss-Prot;Acc:G5EBH0]) HSP 1 Score: 1048.5 bits (2710), Expect = 0.000e+0 Identity = 588/1272 (46.23%), Postives = 816/1272 (64.15%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLER-ISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKS-DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQ-EPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPT-IIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGN--FPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG----KPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIV------------TDKLNANHAREINKKVKVKGSLMRKISH--------------------------------YNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ----EKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
+K F+FNW+ + +L++G+ FDRYD++S LE N VR+DE GFF+ W E + VLD+ Q+ + R G PK+ +I L +R S + +R + I G DLVN+ +V++ E+A + + ++++ +VCP QL K+ L + V IP++ I KTF+SGK EK++ + L +LGL K +E+D TFEKF LY+KICPRT+++E+F +LS K+++T E++I +LNE QRDPRLNEILFPF + + +L +E +Y+++GK+S + F R+LMSD+N PVFLDR+ + DMDQPL HYYINSSHNTYLTGRQ+GGKSS EIYRQVLLSGCRCIELDCWDG GE++ EPIITHGKAMCTD+ FKDV+ IRDTAF S+ P++LSFENHCSK Q K+AKYC D+ GD+LL+KP + L V LPSP +LRKKILIKNKRLK ++E+ QL+ FL+ + EE+E E P+ V GED ++P + K + + HPE+ + + LK + K+ LT EEE+ + A+YHY GATTNIHP LS++VNYT PVKF GFD+AE N+H+HMSSF+E+ GLG +++ V+YNKRQ SRIYP+G RVDS+NF+PQIFWNAGCQMV+LNFQTPD+ MQLN GKFEYNG SGYLLKP+F+RRP+R+FDPFSESP+DGVIAA +++ISGQFLSD+K+GTYVEV+MYGLPTDT RKE +T+V+P NGLNP+Y +D F+FRKVVLP+LAVLR VY++ GK +GQR+LPL+GLQ+GYRHISLR++ N F LS P +F +I TY+P+ L LVDAL+DPRA+LS+++KR + LA MG++ SDI DVP T + K+PP + +++ + G +S S+ + + + D+ K D I + L DK F KL+KR +EL++LRKKH+K + K Q DKL N+ R K+ + SL +S C + + V +++ LV T T EW++M +H +EE +L L+ + +LL K+M E Q++Q LK+ E E K++K QTK S++ K + D+ +K KAERDRR++ELN+ N K F+++RK A K + ++L ++H +Q +K+ A+D E +KE+ LA + + +
Sbjct: 2 AKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVLDMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVELAKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKMVQKCLNDLGLGGDKEREELDVDILTFEKFQRLYNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDIERHQLDQFLREGK--LDEEDELNETPE----VVGEDS----VSPREMPAKENDEAHPELKQNFIAKNLK--------------------GFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDP-FVFRKVVLPELAVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILS-PVLFVQIVIKTYVPDELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSSADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQPARRRNSSIAWIQTNVDKLITNNRRSTKKEKGSRRSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVPQDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLALKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVG----NYKEEQLAAQPTSVV 1237
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Celegans
Match: egl-8 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 [Source:UniProtKB/Swiss-Prot;Acc:G5EBH0]) HSP 1 Score: 1048.11 bits (2709), Expect = 0.000e+0 Identity = 591/1304 (45.32%), Postives = 823/1304 (63.11%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLER-ISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKS-DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQ-EPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKT---------ELNG-------------------------LLKVKEQSDTQLNIKVKEEKEPDSRKN-----------ASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGN--FPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG----KPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISH--------------------------------YNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ----EKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
+K F+FNW+ + +L++G+ FDRYD++S LE N VR+DE GFF+ W E + VLD+ Q+ + R G PK+ +I L +R S + +R + I G DLVN+ +V++ E+A + + ++++ +VCP QL K+ L + V IP++ I KTF+SGK EK++ + L +LGL K +E+D TFEKF LY+KICPRT+++E+F +LS K+++T E++I +LNE QRDPRLNEILFPF + + +L +E +Y+++GK+S + F R+LMSD+N PVFLDR+ + DMDQPL HYYINSSHNTYLTGRQ+GGKSS EIYRQVLLSGCRCIELDCWDG GE++ EPIITHGKAMCTD+ FKDV+ IRDTAF S+ P++LSFENHCSK Q K+AKYC D+ GD+LL+KP + L V LPSP +LRKKILIKNKRLK ++E+ QL+ FL+ + EE+E E P+ V GED ++ D HPE+ + ++G K ++ K +E P+ ++N + K+ LT EEE+ + A+YHY GATTNIHP LS++VNYT PVKF GFD+AE N+H+HMSSF+E+ GLG +++ V+YNKRQ SRIYP+G RVDS+NF+PQIFWNAGCQMV+LNFQTPD+ MQLN GKFEYNG SGYLLKP+F+RRP+R+FDPFSESP+DGVIAA +++ISGQFLSD+K+GTYVEV+MYGLPTDT RKE +T+V+P NGLNP+Y +D F+FRKVVLP+LAVLR VY++ GK +GQR+LPL+GLQ+GYRHISLR++ N F LS P +F +I TY+P+ L LVDAL+DPRA+LS+++KR + LA MG++ SDI DVP T + K+PP + +++ + G +S S+ + + + D+ K D I + L DK F KL+KR +EL++LRKKH+K + K Q DKL N+ R K+ + SL +S C + + V +++ LV T T EW++M +H +EE +L L+ + +LL K+M E Q++Q LK+ E E K++K QTK S++ K + D+ +K KAERDRR++ELN+ N K F+++RK A K + ++L ++H +Q +K+ A+D E +KE+ LA + + +
Sbjct: 2 AKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVLDMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVELAKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKMVQKCLNDLGLGGDKEREELDVDILTFEKFQRLYNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDIERHQLDQFLREGK--LDEEDELNETPE----VVGED--------SVSPPGDQRAHPEVEQPVSSSSPATPSISGPPPCATSSGSTSSITITTTGCSTSSSGPSKHILGGEMPAKENDEAHPELKQNFIAKNLKGFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDP-FVFRKVVLPELAVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILS-PVLFVQIVIKTYVPDELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSSADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQQTNVDKLITNNRRSTKKEKGSRRSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVPQDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLALKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVG----NYKEEQLAAQPTSVV 1285
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Celegans
Match: egl-8 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 [Source:UniProtKB/Swiss-Prot;Acc:G5EBH0]) HSP 1 Score: 1046.19 bits (2704), Expect = 0.000e+0 Identity = 589/1288 (45.73%), Postives = 817/1288 (63.43%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLER-ISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGL-------------PFGKS----------------DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQ-EPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPT-IIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGN--FPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG----KPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISH--------------------------------YNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ----EKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
+K F+FNW+ + +L++G+ FDRYD++S LE N VR+DE GFF+ W E + VLD+ Q+ + R G PK+ +I L +R S + +R + I G DLVN+ +V++ E+A + + ++++ +VCP QL K+ L + V IP++ I KTF+SGK EK++ + L +LGL GK +E+D TFEKF LY+KICPRT+++E+F +LS K+++T E++I +LNE QRDPRLNEILFPF + + +L +E +Y+++GK+S + F R+LMSD+N PVFLDR+ + DMDQPL HYYINSSHNTYLTGRQ+GGKSS EIYRQVLLSGCRCIELDCWDG GE++ EPIITHGKAMCTD+ FKDV+ IRDTAF S+ P++LSFENHCSK Q K+AKYC D+ GD+LL+KP + L V LPSP +LRKKILIKNKRLK ++E+ QL+ FL+ + EE+E E P+ V GED ++P + K + + HPE+ + + LK + K+ LT EEE+ + A+YHY GATTNIHP LS++VNYT PVKF GFD+AE N+H+HMSSF+E+ GLG +++ V+YNKRQ SRIYP+G RVDS+NF+PQIFWNAGCQMV+LNFQTPD+ MQLN GKFEYNG SGYLLKP+F+RRP+R+FDPFSESP+DGVIAA +++ISGQFLSD+K+GTYVEV+MYGLPTDT RKE +T+V+P NGLNP+Y +D F+FRKVVLP+LAVLR VY++ GK +GQR+LPL+GLQ+GYRHISLR++ N F LS P +F +I TY+P+ L LVDAL+DPRA+LS+++KR + LA MG++ SDI DVP T + K+PP + +++ + G +S S+ + + + D+ K D I + L DK F KL+KR +EL++LRKKH+K + K Q DKL N+ R K+ + SL +S C + + V +++ LV T T EW++M +H +EE +L L+ + +LL K+M E Q++Q LK+ E E K++K QTK S++ K + D+ +K KAERDRR++ELN+ N K F+++RK A K + ++L ++H +Q +K+ A+D E +KE+ LA + + +
Sbjct: 2 AKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVLDMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVELAKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKMVQKCLNDLGLGGDKYTPARVINRSMGKKFRNFYKCSRGRKRKEREELDVDILTFEKFQRLYNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDIERHQLDQFLREGK--LDEEDELNETPE----VVGEDS----VSPREMPAKENDEAHPELKQNFIAKNLK--------------------GFGFSKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDP-FVFRKVVLPELAVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILS-PVLFVQIVIKTYVPDELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSSADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQQTNVDKLITNNRRSTKKEKGSRRSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVPQDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLALKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVG----NYKEEQLAAQPTSVV 1253
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Fly
Match: norpA (gene:FBgn0262738 transcript:FBtr0343599) HSP 1 Score: 546.199 bits (1406), Expect = 5.924e-173 Identity = 272/497 (54.73%), Postives = 367/497 (73.84%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDS-----NSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENA 1613
+K +EF+W PV +L G FDR+ E+ N E + L +VDEYGFF++WKSE +G V++L QVSD+R G PK+ KI + ++ LD R +TICS TD +NI+Y H++ D A W++ +R +THN K NN+CPM+ L+KHW+RL V+ +G IPV++++KTFASGKTEK+++ +K+ GLP K+ + FTF+KFY LYHK+CPR DIEE+F ++ K DFI+ E+ I+++N+ QRDPR+NEIL+P + I+++ E EE +K ++S++ F RYLMSD+NAPVFLDRL+ +MDQPLAHYYINSSHNTYL+GRQ GGKSSVE+YRQ LL+GCRC+ELDCW+GKGED+EPI+THG A CT+ILFKD I AI D AFV+SE P+ILSFENHC++ QQYKLAKYC+D GDLLL +P+ H L +PLP P KL++KILIKNKR+KPEVEK +LE++LKG+ + + E+A
Sbjct: 2 TKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKIWLDGIRKITHNVKANNICPMMCLRKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDA 498 HSP 2 Score: 532.332 bits (1370), Expect = 7.162e-168 Identity = 283/638 (44.36%), Postives = 394/638 (61.76%), Query Frame = 3
Query: 1878 HYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR-EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEM-KFKEDLLATKRAT 3785
+Y G+TTN+HP+LS+MVNY QP+KFQGFD A + NI ++MSSF E+ G+ +++ I V+YNKRQ+SRIYP+G R DS+N+MPQ+FWNAGCQMV+LNFQ+ DL MQLNQGKFEYNG GYLLKP+FMRR ++ FDPF+++P+DGVIAA +K+I+GQFLSDKKVGTYVEVDM+GLP+DT +KEFRTR+V NNGLNP+Y +D F+FRKVVLPDLAVLR GVYE++GK++GQR+LPL+GLQ+GYRH+SLRTE NFP+SLP +F I Y+P+G D + LSDPR + +++ +Q+ +GIE + A +G++ P + F EP ++L L +K FQK+ K+Q +EL+ LRKKH K+ + K+Q DKL ++ +I +K S + T +WT M +HRKEE D+ ++ Q+ + +M VQ Q K+L+ R+IK++ A+Q K S D K V ND+ LK K E+DRR+RE N KRF++++K KQ R ++L H +Q +E + + K L++M K +E+ T+ T
Sbjct: 538 NYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDP-FVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQ----------------------------SGGAARDAGKAKEEEKKEPPLVF----------EP----VTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNS--------------------------------------INDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK---LMDMYKIEEEAYKTQGKT 1091
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Fly
Match: norpA (gene:FBgn0262738 transcript:FBtr0100670) HSP 1 Score: 546.199 bits (1406), Expect = 5.924e-173 Identity = 272/497 (54.73%), Postives = 367/497 (73.84%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDS-----NSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENA 1613
+K +EF+W PV +L G FDR+ E+ N E + L +VDEYGFF++WKSE +G V++L QVSD+R G PK+ KI + ++ LD R +TICS TD +NI+Y H++ D A W++ +R +THN K NN+CPM+ L+KHW+RL V+ +G IPV++++KTFASGKTEK+++ +K+ GLP K+ + FTF+KFY LYHK+CPR DIEE+F ++ K DFI+ E+ I+++N+ QRDPR+NEIL+P + I+++ E EE +K ++S++ F RYLMSD+NAPVFLDRL+ +MDQPLAHYYINSSHNTYL+GRQ GGKSSVE+YRQ LL+GCRC+ELDCW+GKGED+EPI+THG A CT+ILFKD I AI D AFV+SE P+ILSFENHC++ QQYKLAKYC+D GDLLL +P+ H L +PLP P KL++KILIKNKR+KPEVEK +LE++LKG+ + + E+A
Sbjct: 2 TKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKIWLDGIRKITHNVKANNICPMMCLRKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDA 498 HSP 2 Score: 532.332 bits (1370), Expect = 7.162e-168 Identity = 283/638 (44.36%), Postives = 394/638 (61.76%), Query Frame = 3
Query: 1878 HYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR-EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEM-KFKEDLLATKRAT 3785
+Y G+TTN+HP+LS+MVNY QP+KFQGFD A + NI ++MSSF E+ G+ +++ I V+YNKRQ+SRIYP+G R DS+N+MPQ+FWNAGCQMV+LNFQ+ DL MQLNQGKFEYNG GYLLKP+FMRR ++ FDPF+++P+DGVIAA +K+I+GQFLSDKKVGTYVEVDM+GLP+DT +KEFRTR+V NNGLNP+Y +D F+FRKVVLPDLAVLR GVYE++GK++GQR+LPL+GLQ+GYRH+SLRTE NFP+SLP +F I Y+P+G D + LSDPR + +++ +Q+ +GIE + A +G++ P + F EP ++L L +K FQK+ K+Q +EL+ LRKKH K+ + K+Q DKL ++ +I +K S + T +WT M +HRKEE D+ ++ Q+ + +M VQ Q K+L+ R+IK++ A+Q K S D K V ND+ LK K E+DRR+RE N KRF++++K KQ R ++L H +Q +E + + K L++M K +E+ T+ T
Sbjct: 538 NYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDP-FVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQ----------------------------SGGAARDAGKAKEEEKKEPPLVF----------EP----VTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNS--------------------------------------INDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK---LMDMYKIEEEAYKTQGKT 1091
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Fly
Match: norpA (gene:FBgn0262738 transcript:FBtr0100671) HSP 1 Score: 546.199 bits (1406), Expect = 5.924e-173 Identity = 272/497 (54.73%), Postives = 367/497 (73.84%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDS-----NSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENA 1613
+K +EF+W PV +L G FDR+ E+ N E + L +VDEYGFF++WKSE +G V++L QVSD+R G PK+ KI + ++ LD R +TICS TD +NI+Y H++ D A W++ +R +THN K NN+CPM+ L+KHW+RL V+ +G IPV++++KTFASGKTEK+++ +K+ GLP K+ + FTF+KFY LYHK+CPR DIEE+F ++ K DFI+ E+ I+++N+ QRDPR+NEIL+P + I+++ E EE +K ++S++ F RYLMSD+NAPVFLDRL+ +MDQPLAHYYINSSHNTYL+GRQ GGKSSVE+YRQ LL+GCRC+ELDCW+GKGED+EPI+THG A CT+ILFKD I AI D AFV+SE P+ILSFENHC++ QQYKLAKYC+D GDLLL +P+ H L +PLP P KL++KILIKNKR+KPEVEK +LE++LKG+ + + E+A
Sbjct: 2 TKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKIWLDGIRKITHNVKANNICPMMCLRKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDA 498 HSP 2 Score: 532.332 bits (1370), Expect = 7.162e-168 Identity = 283/638 (44.36%), Postives = 394/638 (61.76%), Query Frame = 3
Query: 1878 HYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR-EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEM-KFKEDLLATKRAT 3785
+Y G+TTN+HP+LS+MVNY QP+KFQGFD A + NI ++MSSF E+ G+ +++ I V+YNKRQ+SRIYP+G R DS+N+MPQ+FWNAGCQMV+LNFQ+ DL MQLNQGKFEYNG GYLLKP+FMRR ++ FDPF+++P+DGVIAA +K+I+GQFLSDKKVGTYVEVDM+GLP+DT +KEFRTR+V NNGLNP+Y +D F+FRKVVLPDLAVLR GVYE++GK++GQR+LPL+GLQ+GYRH+SLRTE NFP+SLP +F I Y+P+G D + LSDPR + +++ +Q+ +GIE + A +G++ P + F EP ++L L +K FQK+ K+Q +EL+ LRKKH K+ + K+Q DKL ++ +I +K S + T +WT M +HRKEE D+ ++ Q+ + +M VQ Q K+L+ R+IK++ A+Q K S D K V ND+ LK K E+DRR+RE N KRF++++K KQ R ++L H +Q +E + + K L++M K +E+ T+ T
Sbjct: 538 NYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDP-FVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQ----------------------------SGGAARDAGKAKEEEKKEPPLVF----------EP----VTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNS--------------------------------------INDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK---LMDMYKIEEEAYKTQGKT 1091
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Fly
Match: norpA (gene:FBgn0262738 transcript:FBtr0070651) HSP 1 Score: 540.036 bits (1390), Expect = 9.860e-171 Identity = 272/497 (54.73%), Postives = 363/497 (73.04%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDS-----NSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENA 1613
+K +EF+W PV +L G FDR+ E+ N E + L +VDEYGFF++WKSE +G V++L QVSD+R G PK+ KI + ++ LD R +TICS TD +NI+Y H++ D A W NLR +THN + NVCP + L KHW+RL V+ +G IPV++++KTFASGKTEK+++ +K+ GLP K+ + FTF+KFY LYHK+CPR DIEE+F ++ K DFI+ E+ I+++N+ QRDPR+NEIL+P + I+++ E EE +K ++S++ F RYLMSD+NAPVFLDRL+ +MDQPLAHYYINSSHNTYL+GRQ GGKSSVE+YRQ LL+GCRC+ELDCW+GKGED+EPI+THG A CT+ILFKD I AI D AFV+SE P+ILSFENHC++ QQYKLAKYC+D GDLLL +P+ H L +PLP P KL++KILIKNKR+KPEVEK +LE++LKG+ + + E+A
Sbjct: 2 TKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDA 498 HSP 2 Score: 533.102 bits (1372), Expect = 4.672e-168 Identity = 283/638 (44.36%), Postives = 394/638 (61.76%), Query Frame = 3
Query: 1878 HYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR-EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEM-KFKEDLLATKRAT 3785
+Y G+TTN+HP+LS+MVNY QP+KFQGFD A + NI ++MSSF E+ G+ +++ I V+YNKRQ+SRIYP+G R DS+N+MPQ+FWNAGCQMV+LNFQ+ DL MQLNQGKFEYNG GYLLKP+FMRR ++ FDPF+++P+DGVIAA +K+I+GQFLSDKKVGTYVEVDM+GLP+DT +KEFRTR+V NNGLNP+Y +D F+FRKVVLPDLAVLR GVYE++GK++GQR+LPL+GLQ+GYRH+SLRTE NFP+SLP +F I Y+P+G D + LSDPR + +++ +Q+ +GIE + A +G++ P + F EP ++L L +K FQK+ K+Q +EL+ LRKKH K+ + K+Q DKL ++ +I +K S + T +WT M +HRKEE D+ ++ Q+ + +M VQ Q K+L+ R+IK++ A+Q K S D K V ND+ LK K E+DRR+RE N KRF++++K KQ R ++L H +Q +E + + K L++M K +E+ T+ T
Sbjct: 538 NYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDP-FVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQ----------------------------SGGAARDAGKAKEEEKKEPPLVF----------EP----VTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNS--------------------------------------INDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK---LMDMYKIEEEAYKTQGKT 1091
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Fly
Match: norpA (gene:FBgn0262738 transcript:FBtr0301475) HSP 1 Score: 540.036 bits (1390), Expect = 9.860e-171 Identity = 272/497 (54.73%), Postives = 363/497 (73.04%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDS-----NSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENA 1613
+K +EF+W PV +L G FDR+ E+ N E + L +VDEYGFF++WKSE +G V++L QVSD+R G PK+ KI + ++ LD R +TICS TD +NI+Y H++ D A W NLR +THN + NVCP + L KHW+RL V+ +G IPV++++KTFASGKTEK+++ +K+ GLP K+ + FTF+KFY LYHK+CPR DIEE+F ++ K DFI+ E+ I+++N+ QRDPR+NEIL+P + I+++ E EE +K ++S++ F RYLMSD+NAPVFLDRL+ +MDQPLAHYYINSSHNTYL+GRQ GGKSSVE+YRQ LL+GCRC+ELDCW+GKGED+EPI+THG A CT+ILFKD I AI D AFV+SE P+ILSFENHC++ QQYKLAKYC+D GDLLL +P+ H L +PLP P KL++KILIKNKR+KPEVEK +LE++LKG+ + + E+A
Sbjct: 2 TKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDA 498 HSP 2 Score: 533.102 bits (1372), Expect = 4.672e-168 Identity = 283/638 (44.36%), Postives = 394/638 (61.76%), Query Frame = 3
Query: 1878 HYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR-EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEM-KFKEDLLATKRAT 3785
+Y G+TTN+HP+LS+MVNY QP+KFQGFD A + NI ++MSSF E+ G+ +++ I V+YNKRQ+SRIYP+G R DS+N+MPQ+FWNAGCQMV+LNFQ+ DL MQLNQGKFEYNG GYLLKP+FMRR ++ FDPF+++P+DGVIAA +K+I+GQFLSDKKVGTYVEVDM+GLP+DT +KEFRTR+V NNGLNP+Y +D F+FRKVVLPDLAVLR GVYE++GK++GQR+LPL+GLQ+GYRH+SLRTE NFP+SLP +F I Y+P+G D + LSDPR + +++ +Q+ +GIE + A +G++ P + F EP ++L L +K FQK+ K+Q +EL+ LRKKH K+ + K+Q DKL ++ +I +K S + T +WT M +HRKEE D+ ++ Q+ + +M VQ Q K+L+ R+IK++ A+Q K S D K V ND+ LK K E+DRR+RE N KRF++++K KQ R ++L H +Q +E + + K L++M K +E+ T+ T
Sbjct: 538 NYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDP-FVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQ----------------------------SGGAARDAGKAKEEEKKEPPLVF----------EP----VTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNS--------------------------------------INDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK---LMDMYKIEEEAYKTQGKT 1091
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Zebrafish
Match: PLCB4 (phospholipase C beta 4 [Source:NCBI gene;Acc:100537538]) HSP 1 Score: 1105.12 bits (2857), Expect = 0.000e+0 Identity = 614/1179 (52.08%), Postives = 800/1179 (67.85%), Query Frame = 3
Query: 228 EDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKI-CAVLLE-RISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKH--ELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVD-GEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQ-----AMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVP-----------TTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVK-VKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ 3695
+D ESNC +VDE GFF+ WKSE EGQVL+ S ++ +R S K+ K+ CA+ + + L+DRI+ ICSGTDLVN+S+ +MV+Q+ A W + LR L NT+ NNVCPM L+KHW+RL NG IPVRSI++TFASGKTEK IFQ+LK+LGLP GK+DEI FTF+KFY L KICPRTDIE +FK+ K D+++ E+ + +LN+ QRDPRLNEILFPF N I+ EP + G LS + F R+LMSD+NAPVFLDRL + Q+MD PL+HY+INSSHNTYLTGRQFGGKSSVEIYRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTD+LFKDVI I++TAF+TSE P+ILSFENHC+K QQYKLA+YCED+ GDLLL +P++ ++ PLPSP L+ KILIKN+RLKPEVEK+QLE F K + E +P V + ED +E N ++ + HPE ++G L + E+ + + + ++ KE R S +AEEE A++ Y Y+ ATTNIHPYLS ++NY Q VKF GFD AE+ NIH++MSSFNE+VGLG +R + I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG+ G+LLKP+FMRRP+R FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++ F+FRKV+LPDLAVLR+ VY+D KLIGQR+LPL+GLQSGYRHISLR E N PL L T+FC I TY+P+G +VDALSDP+ +LS EKR Q+ MGIE SDI DVP T P K S+ + P + + + +S+V TP + + L+ KTF KLIK+Q +E+ L+KKH K A L S + D+ A H +E + K + + RK+S + L E++ + + M K++++ ++ + E + M H EE + L + E L K++ QE Q +L ++ ER+ KEM+ Q K S++++K + D+ +KNKAER+RR+RELN NT++F+ +RK A KQ ++ ++L EQ
Sbjct: 1 QDPLVFESNCFFKVDESGFFLTWKSEGKEGQVLEFSLINSIRDASALKDPKVLCALEASGKCESNLEDRIICICSGTDLVNLSFMYMVTQNPTTAKEWTDGLRSLIQNTRANNVCPMTCLRKHWMRLSFLTNVNGQIPVRSITRTFASGKTEKGIFQALKDLGLPSGKNDEIQREIFTFDKFYSLTQKICPRTDIEVLFKKFKGDKGDYLSVEQFVHFLNDNQRDPRLNEILFPFFNSKCAFQIIQRYEPVKALVCAGLLSCDGFCRFLMSDENAPVFLDRLEVYQEMDHPLSHYFINSSHNTYLTGRQFGGKSSVEIYRQVLLTGCRCVELDCWDGKGEDQEPIITHGKAMCTDVLFKDVIQGIKETAFLTSEYPVILSFENHCTKHQQYKLARYCEDIFGDLLLKQPLEDFPPKMEPGCPLPSPNDLKGKILIKNRRLKPEVEKKQLEDFRK-----------HMEAGEPSVSTNLFEDENEDETNTAELL---NEAHPE----RIHGCL-ITEEENREEEVLLRHRKE---RCECLTYNSYSAEEENVADELAVIQSYTYVAATTNIHPYLSNIINYAQAVKFTGFDEAEEKNIHHNMSSFNESVGLGYLRTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGFLLKPDFMRRPDRMFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNAEA-FVFRKVILPDLAVLRVAVYDDNNKLIGQRILPLDGLQSGYRHISLRNEYNKPLPLATVFCNIILKTYVPDGFGAIVDALSDPKKFLSICEKRTDQMRAMGIEASDIADVPSDVWKGNKKRKTNQAGMMMKPQKDSDRPREN--MPISSKEVCEPADSSVLTPQLTIDD-------------------LKQTKTFLKLIKKQQKEVNALKKKHAKAHAALRSSHSAQLDRTVAQHEKEKHTLEKQLHKNTSRKVSESSSLEMSRDIEQQMKTAVM---NHKSKVLRIIDVYASECSEMLRWHSAEEQTVVEQHLLQQCEQLHKLLMLEQEQQTHQLTLLHERQSKEMRTNQAKTSMESSKAISQDKSIKNKAERERRVRELNSTNTRKFLTERKRLAMKQTKECEQLQAAQREQ 1132
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Zebrafish
Match: plcb3 (phospholipase C, beta 3 (phosphatidylinositol-specific) [Source:ZFIN;Acc:ZDB-GENE-030616-594]) HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0 Identity = 428/1176 (36.39%), Postives = 656/1176 (55.78%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQG-EGQVLDLSQVSDVR---FGSKPKEDKICAVLLE-RISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHC-SKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQL----EMFLKGQTEIIQEENENAEDPDPLVMVDG--------EDGPMNEINPTIIVKNDTDPHPE-MHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRK-NASKKGS----LTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENS---NQEPLTPNLANKSGQSNNSTVSTPVVG----FSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTK 3614
V++ L G+ F ++DE++NS S +RVD GFF++W E ++LD+S + D R F PK+ +I +L + D R++T+ G DLVNIS+ + + + W + L L N N L K + +L L V +G IPV++I K F+ +K + +L+ GL F + D I P FT+E F +K+ PR ++E IF +L S K F++ +++++++N QRD RLNE+L+P +D V+ +++ E + + ++S+ F +YL ++N V +RL+I DM+QPL+HY+INSSHNTYLT Q G SSVE+YRQVLL+GCRCIELDCW G+ ++EPIITHG M T+I FKDVI AI ++AF TS P+ILSFENH S QQ K+A+YC + GD LL P+DK+ L V QQL E+ K + ++ + A + + DG D P+++ + ++ N + E M K N K ++ D + + + +EE PD +K N + +G+ + A EE + L Y I P VKF+ F++A + MSSF E G+ ++ V+YNK+Q+SRIYP+G RVDS+N+MPQ+FWN GCQMVALNFQT DLAMQLN G FEYNG GYLLKPEFMRR ++ FDPF+ +DG++A T+++KIISGQFL+DKKVG YVEVDM+GLP DT RK +RT+ NN L+P++ DD F+F KVVLP LA LR+ VYE+ GK IG R+LP+ L+ GY +I L+ E N PL LP++ YIP + +AL++P +LS +R QL + ++ PT G P K+ +++S + +P+ P ++ + S + ++ P G NN + E S+ L+ ++ KL+K+Q +E + L KKH K L K Q + ++ ++ R+ ++ K + ++K + ++ E +++ E+QK QM + H + ++ + E ++ L+ + L + E Q Q K+LK + ++E KE++ + +++ ++ R KAE++ IR++N+IN K
Sbjct: 18 VNEVLKRGSKFIKWDEEANSTPSLITLRVDPNGFFLYWTGGTSMEAEILDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAVQDGYCKLWTDELFKLATNMLSQNASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSD---KKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLSPRPEVERIFVDLGSKGKPFLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQLERDQISLMSFTKYLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCRCIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDSAKQQAKMAEYCRSMFGDALLIDPLDKYPL--------------------------VPGQQLPSPQELLGKILIKNKKKHHHRASNGGSIRRKDGTDEQSSPLNDCPLSDGDVGQLMSNGGEKLAERMAKDHDNS--KSIDRGDGESDEEEEEEPIPDPKKHNNTDEGTAYSEVNATEEMSTLVNY--------IEP-----------VKFKSFEVAAKRKKFFEMSSFVETKGMDTLKNSPTEFVEYNKKQMSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLAMQLNMGVFEYNGRCGYLLKPEFMRRTDKHFDPFTTDIVDGIVANTVKVKIISGQFLNDKKVGVYVEVDMFGLPADTKRK-YRTKTSNNNSLDPVW-DDETFVFNKVVLPTLASLRVAVYEENGKFIGHRILPVSALRPGYHYICLKNELNQPLMLPSLLVYTEVQDYIPNEHQEYAEALTNPIKHLSLLAQRESQLLAL-------MEDPTEGGPTKQEEGDGTDSSCVTSADPIFPLPSSPTLPSVPTDLNPPPSGQKEDLVNNVLKVIEPE------SVDELKQHNSYLKLLKKQCKEFKELSKKHLKKMLALSKEQKTLFNQQSSELQRKRSQIEKRIRTSLKKNGSEDSVH--------RELNELDLELQK-QMEQFREEHMQKLLVLRQGQLQMEKEVKQFHLKEANQKLKDIAIECQAAQIKKLKDVCDKEKKELQKMLDRKRLNS---IVEAR----KAEKE--IRDVNEINRK 1110
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Zebrafish
Match: plcb3 (phospholipase C, beta 3 (phosphatidylinositol-specific) [Source:ZFIN;Acc:ZDB-GENE-030616-594]) HSP 1 Score: 659.062 bits (1699), Expect = 0.000e+0 Identity = 428/1162 (36.83%), Postives = 656/1162 (56.45%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQG-EGQVLDLSQVSDVR---FGSKPKEDKICAVLLE-RISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHC-SKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPE-MHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRK-NASKKGS----LTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENS---NQEPLTPNLANKSGQSNNSTVSTPVVG----FSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR---EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELN 3599
V++ L G+ F ++DE++NS S +RVD GFF++W E ++LD+S + D R F PK+ +I +L + D R++T+ G DLVNIS+ + + + W + L L N N L K + +L L V +G IPV++I K F+ +K + +L+ GL F + D I P FT+E F +K+ PR ++E IF +L S K F++ +++++++N QRD RLNE+L+P +D V+ +++ E + + ++S+ F +YL ++N V +RL+I DM+QPL+HY+INSSHNTYLT Q G SSVE+YRQVLL+GCRCIELDCW G+ ++EPIITHG M T+I FKDVI AI ++AF TS P+ILSFENH S QQ K+A+YC + GD LL P+DK+ L LPSP +L KIL ++ ++ I+ ++ E PL D P+++ + ++ N + E M K N K ++ D + + + +EE PD +K N + +G+ + A EE + L Y I P VKF+ F++A + MSSF E G+ ++ V+YNK+Q+SRIYP+G RVDS+N+MPQ+FWN GCQMVALNFQT DLAMQLN G FEYNG GYLLKPEFMRR ++ FDPF+ +DG++A T+++KIISGQFL+DKKVG YVEVDM+GLP DT RK +RT+ NN L+P++ DD F+F KVVLP LA LR+ VYE+ GK IG R+LP+ L+ GY +I L+ E N PL LP++ YIP + +AL++P +LS +R QL + ++ PT G P K+ +++S + +P+ P ++ + S + ++ P G NN + E S+ L+ ++ KL+K+Q +E + L KKH K L K Q + ++ ++ R +I K+++ ++K + ++ E +++ E+QK QM + H + ++ + E ++ L+ + L + E Q Q K+LK + ++E KE++ + +++ ++ R KAE++ + E+N
Sbjct: 18 VNEVLKRGSKFIKWDEEANSTPSLITLRVDPNGFFLYWTGGTSMEAEILDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAVQDGYCKLWTDELFKLATNMLSQNASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSD---KKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLSPRPEVERIFVDLGSKGKPFLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQLERDQISLMSFTKYLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCRCIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDSAKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKIL---------IKNKKKHHHRASNGGSIRRKDGTDEQSSPL-----NDCPLSDGDVGQLMSNGGEKLAERMAKDHDNS--KSIDRGDGESDEEEEEEPIPDPKKHNNTDEGTAYSEVNATEEMSTLVNY--------IEP-----------VKFKSFEVAAKRKKFFEMSSFVETKGMDTLKNSPTEFVEYNKKQMSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLAMQLNMGVFEYNGRCGYLLKPEFMRRTDKHFDPFTTDIVDGIVANTVKVKIISGQFLNDKKVGVYVEVDMFGLPADTKRK-YRTKTSNNNSLDPVW-DDETFVFNKVVLPTLASLRVAVYEENGKFIGHRILPVSALRPGYHYICLKNELNQPLMLPSLLVYTEVQDYIPNEHQEYAEALTNPIKHLSLLAQRESQLLAL-------MEDPTEGGPTKQEEGDGTDSSCVTSADPIFPLPSSPTLPSVPTDLNPPPSGQKEDLVNNVLKVIEPE------SVDELKQHNSYLKLLKKQCKEFKELSKKHLKKMLALSKEQKTLFNQQSSELQRKRSQIEKRIRTS---LKKNGSEDSVH--------RELNELDLELQK-QMEQFREEHMQKLLVLRQGQLQMEKEVKQFHLKEANQKLKDIAIECQAAQIKKLKDVCDKEKKELQKMLDRKRLNS---IVEAR----KAEKEIDVNEIN 1107
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Zebrafish
Match: CABZ01072157.1 (pep chromosome:GRCz11:17:2348540:2386569:-1 gene:ENSDARG00000090381.3 transcript:ENSDART00000121614.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01072157.1) HSP 1 Score: 302.753 bits (774), Expect = 6.709e-88 Identity = 146/285 (51.23%), Postives = 196/285 (68.77%), Query Frame = 3
Query: 1887 GATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPN-NGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDP 2738
G + +SA+VNY QP KF F+ A N + +SSF E G LI ++ + V+YNKRQLSRIYP+G RVDS+N+ PQ FW+AGCQ VALN+QT D MQLN FE+NG +GYLLK + MRR ++ FDPF + +D +IA+TL IKI SGQFLSDK V T VEV++ GLP D RK +RT++ NG+NP + ++ F+F KV+LP++A LR+ V E+ GK IG R++PL+ LQ+G++HI LR+E N PL LP++F I Y+P D DAL +P
Sbjct: 139 GQEVTAYEEMSALVNYVQPNKFISFENAAKKNRCFVISSFVETKGESLIAKNAVDWVEYNKRQLSRIYPKGTRVDSSNYSPQPFWSAGCQFVALNYQTMDFPMQLNMALFEFNGRTGYLLKHDVMRRSDKKFDPFCDR-IDTIIASTLTIKIYSGQFLSDKAVKTGVEVELIGLPKDPKRK-YRTKMSSTANGINPDWNEEP-FIFEKVLLPEMAYLRLVVQEEGGKFIGHRIIPLDALQTGFQHIGLRSESNMPLMLPSLFVHIEMKDYVPAAFADFSDALFNP 420
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Zebrafish
Match: BX936422.1 (phospholipase C, eta 1 [Source:NCBI gene;Acc:566479]) HSP 1 Score: 303.523 bits (776), Expect = 1.122e-85 Identity = 224/702 (31.91%), Postives = 334/702 (47.58%), Query Frame = 3
Query: 747 SFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQT--EIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTE------LNGLLKV-----KEQSDT---------------------------QLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIG---ATTNIHPYLSAMVNYTQPVKFQ-GFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQ--------FLSDKK--VGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYED--TGK-LIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKIT 2681
+ TFE+F Y + R D+ + S+ KD +T E++ +L Q+ + I++ E SEE ++ G L IE F Y+ S I QDMDQP+ +Y+I SSHNTYLTG Q S ++Y VL +GCRC+E+DCWDG D EP++ HG + + I FK VI I AFV +E P+ILS ENHCS QQ K+A++ +++ GD L ++ +A+ +L ++ LKG+ + + E E D D +EI +KN T P H+ E L+ L+K KE +D+ L+ V ++ SR + +++ Q++ G T + LS +V +T V Q D N+ SF+E L+ + +N+RQLSRIYP R+DS+NF PQ +WN GCQ+VALN+QT MQLN+ KF NG SGY+LKP M + +F+P S+ P+ L IKIISGQ L D+ + +VEV++ GLP D +++ TRVV +NG NP++ + F +P++A++R V++ G+ +GQR + L GYRH+ L EG ++ +IF IT
Sbjct: 189 TLTFEEFTVFYKMMSLRRDLFLLLMCFSDKKDHLTAEELGNFLRVEQK--------MSSVTPECCLDIINKFEVSEENKQNGVLGIEGFTNYMRSPACDVFNPQHHEINQDMDQPICNYFIASSHNTYLTGDQLLSHSKTDMYAWVLQAGCRCVEVDCWDGP--DGEPMVQHGYTLTSKITFKSVIETINKYAFVNNEFPVILSIENHCSIQQQKKIAQHLKEIFGDKL--------DVGEALNKDPKQLPSPNLLKG-------------KILLKGKRLPSYLSADAEEGEVSD--------DDSADEIEDDFKLKNSTSNGPSQHQVESHIRKKLDSLMKESQIGDKEDTDSFSIRALLRATHEGLQRNLRKLALFLSLTLSFSVFPQRHSKSRLKCQSVETEDDSQQEPSGGQFNRCGRRRKTIKLSRDLSDLVVFTNSVASQECLDEGSPCNV----LSFSEARAQNLVHHRAERFLTFNQRQLSRIYPSAYRIDSSNFNPQTYWNVGCQLVALNYQTEGRMMQLNRAKFMVNGGSGYVLKPSLMSKG--AFNPLSDEPLPANPKKQLVIKIISGQQLPKPPDSMLGDRGEIIDPFVEVEIIGLPVDCCKEQ--TRVVDDNGFNPVWEETLSFTLH---MPEVALVRFLVWDHDPIGRDFVGQRTIAFSSLMPGYRHVYL--EG---MTEASIFVHIT 835
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Xenopus
Match: ppp1r16b (protein phosphatase 1 regulatory subunit 16B [Source:Xenbase;Acc:XB-GENE-982398]) HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0 Identity = 642/1169 (54.92%), Postives = 837/1169 (71.60%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEP-LTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNA-------NHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V + +GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R+G+ PK+ KI + L + + LD +I+ +C GTDLVNIS+T+MV++ E+A W+ L+ +THN + NNV PM LKKHW++L +G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+PS+FTF+KFYEL KICPRTD EE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K G++S F RYLMSD+NAPVFLDRL + Q+M+ PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI+DTAFVTSE P+ILSFENHCSK QQYK++KYCE++ GDLLL+K ++ H L PLPSP L++KILIKNKRLK EVEK+QLE + + E E A P ++ D E+ N + + HPE + L + S + K+ E ++N +KKG++T E+EQA +A Y Y+GATTNIHP+LS+M+NY QPVKFQGF +AE+ NIH++MSSFNE+VGLG ++ + V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y D+ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP DKK + SN + +TP S + S + P G N K D + + L+ K F K K+Q +E+ L+KKH K+ +++ K Q DK+ A +H R + K +K KG+ NC +K++ + ++ K+++ D+V HT E+T M EE L L + ELL ++++ + Q ++LK+ +RE KEMKA Q K S++ K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKVYEFNWQKAVPSFMQDGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRYGAVPKDPKILSALEAVGKAEQELDGKILCVCCGTDLVNISFTYMVAESAELAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNISGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPSAFTFDKFYELTQKICPRTDTEELFKKINGDKSDYLTVDQLVSFLNEHQRDPRLNEILFPFFDAKRAMQIIETYEPDEELKKAGQISSHGFCRYLMSDENAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKDTAFVTSEYPVILSFENHCSKYQQYKMSKYCEEIFGDLLLSKALESHPLDTGRPLPSPNDLKRKILIKNKRLKAEVEKKQLEAL-----KSMMEAGETA-TPVSILEDDIEEEIEN-------ADQEEEAHPEF---KFGSELSSDDLSQKEAANIAKKMAEDAEQENNNKKGAITVEDEQAWMASYKYVGATTNIHPFLSSMINYAQPVKFQGFKVAEERNIHFNMSSFNESVGLGYLKTHALEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNDEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPADN----TKNDKKGKTSNAKTNVTP---QSSSEVRPSVTAAPGAGTENKKAID------IPQVKVEELKQMKAFLKQQKKQQKEIAALKKKHLKEHSVVQKLQCTQVDKIVAQFDKEKVSHERTLEKSIKKKGA-------SNC---HEMKKETENKIQVLTSDHKSKVKDIVAQHTKEFTEMVKAQNAEEQTLRDVHLSQQCELLKELLRGIHAQQMQQLKLTHDRESKEMKANQAKLSMENCKAISQDKSIKNKAERERRVRELNSSNTKKFL 1130
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Xenopus
Match: ppp1r16b (protein phosphatase 1 regulatory subunit 16B [Source:Xenbase;Acc:XB-GENE-982398]) HSP 1 Score: 1233.01 bits (3189), Expect = 0.000e+0 Identity = 640/1169 (54.75%), Postives = 834/1169 (71.34%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEP-LTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNA-------NHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V + +GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R+G+ PK+ KI + L + + LD +I+ +C GTDLVNIS+T+MV++ E+A W+ L+ +THN + NNV PM LKKHW++L +G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+PS+FTF+KFYEL KICPRTD EE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K G++S F RYLMSD+NAPVFLDRL + Q+M+ PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI+DTAFVTSE P+ILSFENHCSK QQYK++KYCE++ GDLLL+K ++ H L PLPSP L++KILIKNKRLK EVEK+QLE + + E E A P ++ D E+ N + + HPE + L + S + K+ E ++N +KKG++T E+EQA +A Y Y+GATTNIHP+LS+M+NY QPVKFQGF +AE+ NIH++MSSFNE+VGLG ++ + V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y D+ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP DKK + SN + +TP S + S + P G N K + L + F K K+Q +E+ L+KKH K+ +++ K Q DK+ A +H R + K +K KG+ NC +K++ + ++ K+++ D+V HT E+T M EE L L + ELL ++++ + Q ++LK+ +RE KEMKA Q K S++ K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKVYEFNWQKAVPSFMQDGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRYGAVPKDPKILSALEAVGKAEQELDGKILCVCCGTDLVNISFTYMVAESAELAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNISGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPSAFTFDKFYELTQKICPRTDTEELFKKINGDKSDYLTVDQLVSFLNEHQRDPRLNEILFPFFDAKRAMQIIETYEPDEELKKAGQISSHGFCRYLMSDENAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKDTAFVTSEYPVILSFENHCSKYQQYKMSKYCEEIFGDLLLSKALESHPLDTGRPLPSPNDLKRKILIKNKRLKAEVEKKQLEAL-----KSMMEAGETA-TPVSILEDDIEEEIEN-------ADQEEEAHPEF---KFGSELSSDDLSQKEAANIAKKMAEDAEQENNNKKGAITVEDEQAWMASYKYVGATTNIHPFLSSMINYAQPVKFQGFKVAEERNIHFNMSSFNESVGLGYLKTHALEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNDEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPADN----TKNDKKGKTSNAKTNVTP---QSSSEVRPSVTAAPGAGTENKKGKSSR------------LVSAPAFLKQQKKQQKEIAALKKKHLKEHSVVQKLQCTQVDKIVAQFDKEKVSHERTLEKSIKKKGA-------SNC---HEMKKETENKIQVLTSDHKSKVKDIVAQHTKEFTEMVKAQNAEEQTLRDVHLSQQCELLKELLRGIHAQQMQQLKLTHDRESKEMKANQAKLSMENCKAISQDKSIKNKAERERRVRELNSSNTKKFL 1124
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Xenopus
Match: ppp1r16b (protein phosphatase 1 regulatory subunit 16B [Source:Xenbase;Acc:XB-GENE-982398]) HSP 1 Score: 1230.7 bits (3183), Expect = 0.000e+0 Identity = 640/1169 (54.75%), Postives = 834/1169 (71.34%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEP-LTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNA-------NHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V + +GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R+G+ PK+ KI + L + + LD +I+ +C GTDLVNIS+T+MV++ E+A W+ L+ +THN + NNV PM LKKHW++L +G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+PS+FTF+KFYEL KICPRTD EE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K G++S F RYLMSD+NAPVFLDRL + Q+M+ PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI+DTAFVTSE P+ILSFENHCSK QQYK++KYCE++ GDLLL+K ++ H L PLPSP L++KILIKNKRLK EVEK+QLE + + E E A P ++ D E+ N + + HPE + L + S + K+ E ++N +KKG++T E+EQA +A Y Y+GATTNIHP+LS+M+NY QPVKFQGF +AE+ NIH++MSSFNE+VGLG ++ + V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y D+ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP DKK + SN + +TP S + S + P G N K + L + F K K+Q +E+ L+KKH K+ +++ K Q DK+ A +H R + K +K KG+ NC +K++ + ++ K+++ D+V HT E+T M EE L L + ELL ++++ + Q ++LK+ +RE KEMKA Q K S++ K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKVYEFNWQKAVPSFMQDGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRYGAVPKDPKILSALEAVGKAEQELDGKILCVCCGTDLVNISFTYMVAESAELAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNISGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPSAFTFDKFYELTQKICPRTDTEELFKKINGDKSDYLTVDQLVSFLNEHQRDPRLNEILFPFFDAKRAMQIIETYEPDEELKKAGQISSHGFCRYLMSDENAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKDTAFVTSEYPVILSFENHCSKYQQYKMSKYCEEIFGDLLLSKALESHPLDTGRPLPSPNDLKRKILIKNKRLKAEVEKKQLEAL-----KSMMEAGETA-TPVSILEDDIEEEIEN-------ADQEEEAHPEF---KFGSELSSDDLSQKEAANIAKKMAEDAEQENNNKKGAITVEDEQAWMASYKYVGATTNIHPFLSSMINYAQPVKFQGFKVAEERNIHFNMSSFNESVGLGYLKTHALEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNDEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPADN----TKNDKKGKTSNAKTNVTP---QSSSEVRPSVTAAPGAGTENKKGKSSR------------LVSAPAFLKQQKKQQKEIAALKKKHLKEHSVVQKLQCTQVDKIVAQFDKEKVSHERTLEKSIKKKGA-------SNC---HEMKKETENKIQVLTSDHKSKVKDIVAQHTKEFTEMVKAQNAEEQTLRDVHLSQQCELLKELLRGIHAQQMQQLKLTHDRESKEMKANQAKLSMENCKAISQDKSIKNKAERERRVRELNSSNTKKFL 1124
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Xenopus
Match: ppp1r16b (protein phosphatase 1 regulatory subunit 16B [Source:Xenbase;Acc:XB-GENE-982398]) HSP 1 Score: 1228.39 bits (3177), Expect = 0.000e+0 Identity = 639/1169 (54.66%), Postives = 832/1169 (71.17%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEP-LTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNA-------NHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V + +GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R+G+ PK+ KI + L + + LD +I+ +C GTDLVNIS+T+MV++ E+A W+ L+ +THN + NNV PM LKKHW++L +G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+PS+FTF+KFYEL KICPRTD EE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K G++S F RYLMSD+NAPVFLDRL + Q+M+ PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI+DTAFVTSE P+ILSFENHCSK QQYK++KYCE++ GDLLL+K ++ H L PLPSP L++KILIKNKRLK EVEK+QLE + + E E A P ++ D E+ N + + HPE + ++L+ +KE N +KKG++T E+EQA +A Y Y+GATTNIHP+LS+M+NY QPVKFQGF +AE+ NIH++MSSFNE+VGLG ++ + V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y D+ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP DKK + SN + +TP S + S + P G N K + L + F K K+Q +E+ L+KKH K+ +++ K Q DK+ A +H R + K +K KG+ NC +K++ + ++ K+++ D+V HT E+T M EE L L + ELL ++++ + Q ++LK+ +RE KEMKA Q K S++ K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKVYEFNWQKAVPSFMQDGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRYGAVPKDPKILSALEAVGKAEQELDGKILCVCCGTDLVNISFTYMVAESAELAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNISGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPSAFTFDKFYELTQKICPRTDTEELFKKINGDKSDYLTVDQLVSFLNEHQRDPRLNEILFPFFDAKRAMQIIETYEPDEELKKAGQISSHGFCRYLMSDENAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKDTAFVTSEYPVILSFENHCSKYQQYKMSKYCEEIFGDLLLSKALESHPLDTGRPLPSPNDLKRKILIKNKRLKAEVEKKQLEAL-----KSMMEAGETA-TPVSILEDDIEEEIEN-------ADQEEEAHPEF-------------KFGSELSSDDLSQKEA---ANIAKKGAITVEDEQAWMASYKYVGATTNIHPFLSSMINYAQPVKFQGFKVAEERNIHFNMSSFNESVGLGYLKTHALEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNDEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPADN----TKNDKKGKTSNAKTNVTP---QSSSEVRPSVTAAPGAGTENKKGKSSR------------LVSAPAFLKQQKKQQKEIAALKKKHLKEHSVVQKLQCTQVDKIVAQFDKEKVSHERTLEKSIKKKGA-------SNC---HEMKKETENKIQVLTSDHKSKVKDIVAQHTKEFTEMVKAQNAEEQTLRDVHLSQQCELLKELLRGIHAQQMQQLKLTHDRESKEMKANQAKLSMENCKAISQDKSIKNKAERERRVRELNSSNTKKFL 1111
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Xenopus
Match: ppp1r16b (protein phosphatase 1 regulatory subunit 16B [Source:Xenbase;Acc:XB-GENE-982398]) HSP 1 Score: 1226.85 bits (3173), Expect = 0.000e+0 Identity = 639/1169 (54.66%), Postives = 832/1169 (71.17%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEP-LTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNA-------NHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V + +GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R+G+ PK+ KI + L + + LD +I+ +C GTDLVNIS+T+MV++ E+A W+ L+ +THN + NNV PM LKKHW++L +G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+PS+FTF+KFYEL KICPRTD EE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K G++S F RYLMSD+NAPVFLDRL + Q+M+ PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI+DTAFVTSE P+ILSFENHCSK QQYK++KYCE++ GDLLL+K ++ H L PLPSP L++KILIKNKRLK EVEK+QLE + + E E A P ++ D E+ N + + HPE + ++L+ +KE N +KKG++T E+EQA +A Y Y+GATTNIHP+LS+M+NY QPVKFQGF +AE+ NIH++MSSFNE+VGLG ++ + V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y D+ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP DKK + SN + +TP S + S + P G N K + L + F K K+Q +E+ L+KKH K+ +++ K Q DK+ A +H R + K +K KG+ NC +K++ + ++ K+++ D+V HT E+T M EE L L + ELL ++++ + Q ++LK+ +RE KEMKA Q K S++ K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKVYEFNWQKAVPSFMQDGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRYGAVPKDPKILSALEAVGKAEQELDGKILCVCCGTDLVNISFTYMVAESAELAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNISGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPSAFTFDKFYELTQKICPRTDTEELFKKINGDKSDYLTVDQLVSFLNEHQRDPRLNEILFPFFDAKRAMQIIETYEPDEELKKAGQISSHGFCRYLMSDENAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKDTAFVTSEYPVILSFENHCSKYQQYKMSKYCEEIFGDLLLSKALESHPLDTGRPLPSPNDLKRKILIKNKRLKAEVEKKQLEAL-----KSMMEAGETA-TPVSILEDDIEEEIEN-------ADQEEEAHPEF-------------KFGSELSSDDLSQKEA---ANIAKKGAITVEDEQAWMASYKYVGATTNIHPFLSSMINYAQPVKFQGFKVAEERNIHFNMSSFNESVGLGYLKTHALEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNDEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPADN----TKNDKKGKTSNAKTNVTP---QSSSEVRPSVTAAPGAGTENKKGKSSR------------LVSAPAFLKQQKKQQKEIAALKKKHLKEHSVVQKLQCTQVDKIVAQFDKEKVSHERTLEKSIKKKGA-------SNC---HEMKKETENKIQVLTSDHKSKVKDIVAQHTKEFTEMVKAQNAEEQTLRDVHLSQQCELLKELLRGIHAQQMQQLKLTHDRESKEMKANQAKLSMENCKAISQDKSIKNKAERERRVRELNSSNTKKFL 1111
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Mouse
Match: Plcb4 (phospholipase C, beta 4 [Source:MGI Symbol;Acc:MGI:107464]) HSP 1 Score: 1243.02 bits (3215), Expect = 0.000e+0 Identity = 639/1161 (55.04%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R + PK+ KI A L + + N L+ RI+ +CSGTDLVNI +T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++FT+EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L PLPSP L++KILIKNKRLKPEVEK+QLE ++ E E P ++ ED EI + + HPE + +L+ KE + N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + P AN + QS++ T + ++ K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRQAAIPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTTGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEA--------LKSMMEAGESAAPASIL--EDDNEEEIES---ADQEEEAHPEY-------------KFGNELSADDYSHKE--AVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EIKKETEIKIQTLTTDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Mouse
Match: Plcb4 (phospholipase C, beta 4 [Source:MGI Symbol;Acc:MGI:107464]) HSP 1 Score: 1243.02 bits (3215), Expect = 0.000e+0 Identity = 639/1161 (55.04%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R + PK+ KI A L + + N L+ RI+ +CSGTDLVNI +T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++FT+EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L PLPSP L++KILIKNKRLKPEVEK+QLE ++ E E P ++ ED EI + + HPE + +L+ KE + N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + P AN + QS++ T + ++ K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRQAAIPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTTGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEA--------LKSMMEAGESAAPASIL--EDDNEEEIES---ADQEEEAHPEY-------------KFGNELSADDYSHKE--AVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EIKKETEIKIQTLTTDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Mouse
Match: Plcb4 (phospholipase C, beta 4 [Source:MGI Symbol;Acc:MGI:107464]) HSP 1 Score: 1162.13 bits (3005), Expect = 0.000e+0 Identity = 592/1031 (57.42%), Postives = 753/1031 (73.04%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCL 3233
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R + PK+ KI A L + + N L+ RI+ +CSGTDLVNI +T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++FT+EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L PLPSP L++KILIKNKRLKPEVEK+QLE ++ E E P ++ ED EI + + HPE + +L+ KE + N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + P AN + QS++ T + ++ K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRQAAIPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTTGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEA--------LKSMMEAGESAAPASIL--EDDNEEEIES---ADQEEEAHPEY-------------KFGNELSADDYSHKE--AVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPS----------DTSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL 992
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Mouse
Match: Plcb4 (phospholipase C, beta 4 [Source:MGI Symbol;Acc:MGI:107464]) HSP 1 Score: 1122.84 bits (2903), Expect = 0.000e+0 Identity = 558/895 (62.35%), Postives = 694/895 (77.54%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPT 2825
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R + PK+ KI A L + + N L+ RI+ +CSGTDLVNI +T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++FT+EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L PLPSP L++KILIKNKRLKPEVEK+QLE ++ E E P ++ ED EI + + HPE + L + S + ++ D +KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRQAAIPKDPKILAALEAVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTTGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEA--------LKSMMEAGESAAPASIL--EDDNEEEIESA---DQEEEAHPEY---KFGNELSADDYSHKEAVANSVKKTSDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPS 879
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Mouse
Match: Plcb1 (phospholipase C, beta 1 [Source:MGI Symbol;Acc:MGI:97613]) HSP 1 Score: 382.489 bits (981), Expect = 5.805e-112 Identity = 194/427 (45.43%), Postives = 275/427 (64.40%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSEN---------SNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR 3167
+S +VNY QPVKF+ F+I++ N + MSSF E GL + + + V+YNK QLSRIYP+G RVDS+N+MPQ+FWNAGCQMVALNFQT DLAMQ+N G +EYNG SGY LKPEFMRRP++ FDPF+E +DG++A TL +KIISGQFLSDKKVGTYVEVDM+GLP DT RK F+T+ N +NP++ ++ + +F+KVVLP LA LRI YE+ GK IG R+LP++ ++ GY +I LR E N PL+LP +F I Y+P+ D+++ALS+P Y++ E+R KQLA + +E D +V P + + SE ++ L P +++ S + S + + E + I L+ K+F KL K+ +E+++L K+H K + L K T +++ ++ R
Sbjct: 540 MSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPI-VFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLE--DEEEVKKEADPGETSSEAPSETRTTPAENGVNHTASLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE--ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLR 961 HSP 2 Score: 357.066 bits (915), Expect = 5.452e-103 Identity = 181/436 (41.51%), Postives = 277/436 (63.53%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGS---KPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKP-QQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
VSD L G F ++D+DS ++ + ++R D GFF +W + E ++LDLS V D R G PK+ K+ +L L+ R++T+ G DLVNIS+ ++V+ E+A W N + L N N+ L+K + +L L V G IP+++I + F++ + K + +L+ LP ++D I FT + + + +CPR +I+ IF E + SK ++T +++++++N QRDPRLNEIL+P ++ V+ +++ EP+ K+G++S++ F RYL ++N V ++L++ +DM QPL+HY+INSSHNTYLT Q G SSVE+YRQVLLSGCRC+ELDCW G+ ++EP+ITHG M T+I FK+VI AI + AF TS PI+LSFENH P QQ K+A+YC + GD LL +P++K+ L V
Sbjct: 18 VSDSLKKGTKFVKWDDDS-TIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADR--KRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGV 450
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q15147|PLCB4_HUMAN (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4 PE=1 SV=3) HSP 1 Score: 1246.11 bits (3223), Expect = 0.000e+0 Identity = 640/1161 (55.12%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ W+SE EGQVL+ S ++ +R G+ PK+ KI A L + + N L+ RIV +CSGTDLVNIS+T+MV+++ E+ W+ LR + HN + NNV PM LKKHW++L NG IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++F++EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE + E E+A + L ED EI + + HPE E S L K ++ N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T ++ + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRS-----MMEAGESASPANIL-----EDDNEEEIES---ADQEEEAHPEFKFG--------NELSADDLGHK-------EAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9QW07|PLCB4_RAT (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Rattus norvegicus OX=10116 GN=Plcb4 PE=1 SV=2) HSP 1 Score: 1245.72 bits (3222), Expect = 0.000e+0 Identity = 639/1161 (55.04%), Postives = 831/1161 (71.58%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
+K +EFNW++ V L GA FDRY+E+S E NCL +VDE+GFF+ WKSE EGQVL+ S ++ +R + PK+ KI A L + + N L+ RI+ +CSGTDLVNI +T+MV+++ EI W+ LR + HN + NNV PM LKKHW++L +G IPVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++FT+EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP EE +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQY+++KYCED+ GDLLL + ++ H L LPSP L++KILIKNKRLKPEVEK+QLE ++ E E P ++ ED EI + + HPE + +L+ KE + N+ KKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR QL MGIETSDI DVP+ S+N + P AN + QS++ T + ++ K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E + K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 2 AKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRLAAIPKDPKILAALESVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEITKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTSGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYQMSKYCEDLFGDLLLKQALESHPLEPGRLLPSPNDLKRKILIKNKRLKPEVEKKQLEA--------LKSMMEAGESAAPASIL--EDDNEEEIES---ADQEEEAHPEY-------------KFGNELSADDFSHKE--AVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQLRAMGIETSDIADVPSD----------TSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIE-LIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCL---EIKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 1119
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q07722|PLCB4_BOVIN (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (Fragment) OS=Bos taurus OX=9913 GN=PLCB4 PE=1 SV=1) HSP 1 Score: 1076.23 bits (2782), Expect = 0.000e+0 Identity = 554/1005 (55.12%), Postives = 716/1005 (71.24%), Query Frame = 3
Query: 633 PVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNE-------INPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
PVRSI++TFASGKTEK+IFQ+LKELGLP GK+DEI+P++FT+EKFYEL KICPRTDIE++FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + I++ EP E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MD PLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLL+GCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSK QQYK++KYCED+ GDLLL + ++ H L PLPSP L++KILIK + + EVEK+QLE ++ E E P+ M++ ++ E +P N+ HK + VK+ SD D SKKG +T E+EQA +A Y Y+GATTNIHPYLS M+NY QPVKFQGF +AE+ NIHY+MSSFNE+VGLG ++ I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWN+GCQMV+LN+QTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R+FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++S F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPTIFC I TY+P+G D+VDALSDP+ +LS EKR Q+ MGIETSDI DVP+ S+N + AN + QS++ T + K E + + L+ K + K +K+Q +EL +L+KKH K+ + + K DK+ A + +E K+ M+K NCL +K++ + + K+++ ++V HT EW+ M H EE ++ L + ELL K++ E Q ++LK+ +RE KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+
Sbjct: 1 PVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKQGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKKQTTETEVEKKQLEA--------LKSMMEAGESAAPVNMLEDDNEEEIESAEQEEEAHPEYKYGNELSADDLGHKEAIAN--SVKKASD-------------DLEHENSKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNSGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEES-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSD----------TSKNDKKGKANTAKANVTPQSSSELRPTTTAALGAGLEAKKGIEL-IPQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKLTHEKILEKAMKKKGGSNCL---EMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRKLLISAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFL 967
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. UniProt/SwissProt
Match: sp|G5EBH0|PLCB_CAEEL (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 OS=Caenorhabditis elegans OX=6239 GN=egl-8 PE=1 SV=1) HSP 1 Score: 579.711 bits (1493), Expect = 0.000e+0 Identity = 322/711 (45.29%), Postives = 449/711 (63.15%), Query Frame = 3
Query: 1821 ASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGN--FPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG----KPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIV------------TDKLNANHAREINKKVKVKGSLMRKISH--------------------------------YNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ----EKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
+ K+ LT EEE+ + A+YHY GATTNIHP LS++VNYT PVKF GFD+AE N+H+HMSSF+E+ GLG +++ V+YNKRQ SRIYP+G RVDS+NF+PQIFWNAGCQMV+LNFQTPD+ MQLN GKFEYNG SGYLLKP+F+RRP+R+FDPFSESP+DGVIAA +++ISGQFLSD+K+GTYVEV+MYGLPTDT RKE +T+V+P NGLNP+Y +D F+FRKVVLP+LAVLR VY++ GK +GQR+LPL+GLQ+GYRHISLR++ N F LS P +F +I TY+P+ L LVDAL+DPRA+LS+++KR + LA MG++ SDI DVP T + K+PP + +++ + G +S S+ + + + D+ K D I + L DK F KL+KR +EL++LRKKH+K + K Q DKL N+ R K+ + SL +S C + + V +++ LV T T EW++M +H +EE +L L+ + +LL K+M E Q++Q LK+ E E K++K QTK S++ K + D+ +K KAERDRR++ELN+ N K F+++RK A K + ++L ++H +Q +K+ A+D E +KE+ LA + + +
Sbjct: 727 SKKQPVLTKEEEERIFAEYHYTGATTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEFVNYNKRQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVISGQFLSDRKIGTYVEVEMYGLPTDTIRKEHKTKVIPGNGLNPVYNEDP-FVFRKVVLPELAVLRFAVYDENGKQLGQRILPLDGLQAGYRHISLRSDTNQSFILS-PVLFVQIVIKTYVPDELSGLVDALADPRAFLSEQKKRQEALAHMGVDDSDIPDVPNTRNMALRHVKQPPRQNGSSADLLANNGQTGSARGDQTSSMASSTIRSPNEQPQPVAVDKFKVDPIEVDDLRRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQPARRRNSSIAWIQTNVDKLITNNRRSTKKEKGSRRSLTASVSSGCGSASGTVTVSVCSPSGASCSGYSTGGPSTPVACNSDGTGSPATIGSPVPQDLVNNDRVRSLVNTQTGEWSAMVRRHDEEEFELKKVQLKEQFDLLRKLMSEAQKNQMLALKLRLEAEGKDLKQTQTKKSMEDAKVIQLDKGIKTKAERDRRVKELNEKNLKMFVEERKRLAMKAQKHEEQLTKRHLDQLEQLDKDFHKALDAEVG----NYKEEQLAAQPTSVV 1431 HSP 2 Score: 474.167 bits (1219), Expect = 3.523e-142 Identity = 260/532 (48.87%), Postives = 353/532 (66.35%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLER-ISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGL-------------PFGKS----------------DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQ-EPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGED 1652
+K F+FNW+ + +L++G+ FDRYD++S LE N VR+DE GFF+ W E + VLD+ Q+ + R G PK+ +I L +R S + +R + I G DLVN+ +V++ E+A + + ++++ +VCP QL K+ L + V IP++ I KTF+SGK EK++ + L +LGL GK +E+D TFEKF LY+KICPRT+++E+F +LS K+++T E++I +LNE QRDPRLNEILFPF + + +L +E +Y+++GK+S + F R+LMSD+N PVFLDR+ + DMDQPL HYYINSSHNTYLTGRQ+GGKSS EIYRQVLLSGCRCIELDCWDG GE++ EPIITHGKAMCTD+ FKDV+ IRDTAF S+ P++LSFENHCSK Q K+AKYC D+ GD+LL+KP + L V LPSP +LRKKILIKNKRLK ++E+ QL+ FL+ + EE+E E P+ V GED
Sbjct: 2 AKEFQFNWKPTIIPELLHGSVFDRYDDESTCLELNAQVRIDENGFFLRWLIEGKDAVVLDMGQIWEARTGGLPKDGRIMFELEQRGASETIAERTIWITHGQDLVNVQSFFLVAESVELAKTCRAGINDILKSSRIRHVCPTTQLMKYHTWLTMNVNERRKIPIKLIIKTFSSGKPEKMVQKCLNDLGLGGDKYTPARVINRSMGKKFRNFYKCSRGRKRKEREELDVDILTFEKFQRLYNKICPRTEVQELFVKLSGQKEYLTKERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSDENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIELDCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQLKMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPNRLRKKILIKNKRLKTDIERHQLDQFLREGK--LDEEDELNETPE----VVGED 527
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. UniProt/SwissProt
Match: sp|P13217|PIPA_DROME (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Drosophila melanogaster OX=7227 GN=norpA PE=1 SV=4) HSP 1 Score: 540.036 bits (1390), Expect = 9.884e-170 Identity = 272/497 (54.73%), Postives = 363/497 (73.04%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDS-----NSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENA 1613
+K +EF+W PV +L G FDR+ E+ N E + L +VDEYGFF++WKSE +G V++L QVSD+R G PK+ KI + ++ LD R +TICS TD +NI+Y H++ D A W NLR +THN + NVCP + L KHW+RL V+ +G IPV++++KTFASGKTEK+++ +K+ GLP K+ + FTF+KFY LYHK+CPR DIEE+F ++ K DFI+ E+ I+++N+ QRDPR+NEIL+P + I+++ E EE +K ++S++ F RYLMSD+NAPVFLDRL+ +MDQPLAHYYINSSHNTYL+GRQ GGKSSVE+YRQ LL+GCRC+ELDCW+GKGED+EPI+THG A CT+ILFKD I AI D AFV+SE P+ILSFENHC++ QQYKLAKYC+D GDLLL +P+ H L +PLP P KL++KILIKNKR+KPEVEK +LE++LKG+ + + E+A
Sbjct: 2 TKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDA 498 HSP 2 Score: 533.102 bits (1372), Expect = 4.684e-167 Identity = 283/638 (44.36%), Postives = 394/638 (61.76%), Query Frame = 3
Query: 1878 HYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR-EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEM-KFKEDLLATKRAT 3785
+Y G+TTN+HP+LS+MVNY QP+KFQGFD A + NI ++MSSF E+ G+ +++ I V+YNKRQ+SRIYP+G R DS+N+MPQ+FWNAGCQMV+LNFQ+ DL MQLNQGKFEYNG GYLLKP+FMRR ++ FDPF+++P+DGVIAA +K+I+GQFLSDKKVGTYVEVDM+GLP+DT +KEFRTR+V NNGLNP+Y +D F+FRKVVLPDLAVLR GVYE++GK++GQR+LPL+GLQ+GYRH+SLRTE NFP+SLP +F I Y+P+G D + LSDPR + +++ +Q+ +GIE + A +G++ P + F EP ++L L +K FQK+ K+Q +EL+ LRKKH K+ + K+Q DKL ++ +I +K S + T +WT M +HRKEE D+ ++ Q+ + +M VQ Q K+L+ R+IK++ A+Q K S D K V ND+ LK K E+DRR+RE N KRF++++K KQ R ++L H +Q +E + + K L++M K +E+ T+ T
Sbjct: 538 NYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDP-FVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQ----------------------------SGGAARDAGKAKEEEKKEPPLVF----------EP----VTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNS--------------------------------------INDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQK---LMDMYKIEEEAYKTQGKT 1091
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. TrEMBL
Match: A0A0X3P0N3 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Schistocephalus solidus OX=70667 GN=TR168281 PE=4 SV=1) HSP 1 Score: 1610.12 bits (4168), Expect = 0.000e+0 Identity = 803/1231 (65.23%), Postives = 990/1231 (80.42%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN-PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKN-DTDPHPEMHKTELNGL-LKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
M+SDIAKRQRTVPS+K ++F WR+PV L GA+FDR+DE++ +E C +RVDE GFF+ WKSE EGQVL+LSQVSDVR G KPK++K+ ++L ER +N PLD+R++T+CSG DLVNISYT+ V+ E+A +WI ++R LTHNTK NVCPM QL+KHWLR+ L V G IPVR ++KTFASG+ E+IIFQSLKELGLP GK+DE++PS FTFE+FYELYHKICPRTDIEE+FK LSN K I+ EK++E+LNEVQRDPRLNEIL+P+AN+ T++YI + EP E+ + L++ECFYRYLMSDDNAPVFLDRL+I QDMDQPL HYYINSSHNTYL GRQFGGKSSVEIYRQVLL+GCRCIELDCWDGKG+DQEPIITHGKAMCTDILFKDVIYA+RDTAFVTS+ P+I+SFENHCSK QQ+KLAKYCED+LGDLLLTKPIDKH L PLPSP KL++KIL+KNKRL P+VEK QLE+FLKGQT+ IQEE E+++ D + VDGE GP+N+++PT+ K D DPHPE +G + S + L ++ E E N ++GSLT EEEQAMLAQYHY GATT IHP LS+MVNY Q VKFQGFD+AE+ N+ +H+SSFNEN LGLI+ C V YNKRQ+SRIYPRGNRVDS+N+MPQIFWNAGCQMVALNFQTPDLAMQLNQG+FEYNGN G+LLKPEFMRRPER FDPFSESPMDGVIAAT E++IISGQFLSD+KVGTYVEVDMYGLPTDT RKEFRTRVVPNNGLNP+YG+D+VF+FRKVVLPDLAVLR VYEDTGKLIGQRVLPL+GLQSGYRHISLRTEGNFPLSLPT+FC+++ TTY+PEGL DLVDALSDPRA+LSKEE+RMKQLA MGI++S+I DVP T K K+ + + + + + G + ST +++KK++K+++PKF ISL +L DK ++KL+K+Q ++LE LR++HEK+++ + ++ TI+TDKLNA HA+ +K + + N + ++++QK++M DLV+ TD+W+S+K Q KE H L ++F+++R+ELLLKV++E EDQK+ELK IQERE KEMKAQQTK SI++N+ V+ DRKLKNKAERDRRIRELND NTKRFIDQRKAQAQ+ +RQ QEL R+HDE+E+ VV+ +++ER L ++E+LLA+KR T I
Sbjct: 1 MSSDIAKRQRTVPSAKVYDFVWRRPVPPALREGAYFDRFDEETGIVELGCFLRVDEDGFFLFWKSEANEGQVLELSQVSDVRQGCKPKDEKVVSILTERFANRPLDERVMTVCSGLDLVNISYTNFVASTPEVAAWWIQSVRGLTHNTKAQNVCPMTQLRKHWLRITLTVNPRGKIPVRVVTKTFASGRNERIIFQSLKELGLPSGKNDEVEPSEFTFERFYELYHKICPRTDIEELFKSLSNGKPTISHEKMMEFLNEVQRDPRLNEILYPYANRQTIRYIQEAYEPQEKSASQDGLTLECFYRYLMSDDNAPVFLDRLDIYQDMDQPLCHYYINSSHNTYLIGRQFGGKSSVEIYRQVLLAGCRCIELDCWDGKGDDQEPIITHGKAMCTDILFKDVIYAVRDTAFVTSDCPVIMSFENHCSKHQQFKLAKYCEDILGDLLLTKPIDKHPLEPGYPLPSPEKLKRKILVKNKRLTPDVEKHQLELFLKGQTDPIQEETESSDLADTIACVDGEVGPLNDLDPTMPPKPLDIDPHPETKSRPGSGTTINTLSPSGSSLPCRLSE-AEMKRLVNKKEEGSLTVEEEQAMLAQYHYTGATTAIHPLLSSMVNYAQAVKFQGFDVAEERNLSFHVSSFNENRALGLIKCYCTEFVVYNKRQMSRIYPRGNRVDSSNYMPQIFWNAGCQMVALNFQTPDLAMQLNQGRFEYNGNCGFLLKPEFMRRPERQFDPFSESPMDGVIAATCEVRIISGQFLSDRKVGTYVEVDMYGLPTDTIRKEFRTRVVPNNGLNPVYGEDAVFVFRKVVLPDLAVLRFAVYEDTGKLIGQRVLPLDGLQSGYRHISLRTEGNFPLSLPTLFCRVSLTTYVPEGLNDLVDALSDPRAFLSKEEQRMKQLASMGIDSSEIADVPATTKSLKRSGQSRVGVT----VNSSCPSSCGIDRPAGTSTSASNVNSSKKEEKREDPKFPGISLGMLRNDKNYRKLVKKQAKDLELLRRRHEKEASTMLRAHTILTDKLNAAHAK---ASAGIKAAAQKS----------------NGVNSQLKDLQKSEMSDLVRQQTDQWSSLKAQQMKEVHHLVLTFMDARKELLLKVLREAHEDQKRELKQIQERENKEMKAQQTKISIESNRTVLGDRKLKNKAERDRRIRELNDYNTKRFIDQRKAQAQRNERQIQELCRRHDEEEQGVVTGVNRERDELIHSYQEELLASKRTTVI 1207
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. TrEMBL
Match: A0A4Z2CYF8 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Schistosoma japonicum OX=6182 GN=EWB00_006501 PE=4 SV=1) HSP 1 Score: 1586.24 bits (4106), Expect = 0.000e+0 Identity = 811/1234 (65.72%), Postives = 988/1234 (80.06%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDG-PMN-----EINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPS+KAFEF W++PV + L +G HFDRYDE++ LE NC VRVD+ GFF++W+SE + Q L+LSQ+SDVR G+KPK++K+ A + ER S DRIVTICSG DLVNI+YTHMV++D E A+FWI +LR LTHNTK NVCPM QL+KHWLRL L V A IPVR I KTFASG+ E+I++QSLK+L LP GK+D+IDP+ F FEKFYELYHKICPRTDIE++FK LS K+ I +K+IE+LNE QRDPRLNEIL+PFANK T+KYI +N E EE++ ++SIECFYRYLMSDDNA VFLD+L+I QDMDQPL+HYYINSSHNTYL GRQFGGKSSVEIYRQVLL+GCRCIELDCWDG+GEDQEPIITHGKAMC+DILFKDVIYAIRDTAFV S+ P+I+SFENHCSK QQYKLAKYCE++LGD+LLTKP+D + L VPLP P KL++KILIKNKRLKPE EKQQLE+FLKGQT+ IQEENE EDPD + D DG P N +++ T I +D + L S +++K+E+ G+LTAEEEQ M+A YHY GAT++IHP LS+ +NY QPVKFQGFD+AED NIH+HMSSF+E + LGL++ I V+YNKRQ+SRIYPRGNRVDS+N+MPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGN GYLLKPEFMRRPER FDPFSESPMDGVIAAT E+KIISGQFLSD+KVGTYVEVDMYGLPTDT RKEFRTRVVPNNGLNP+YGDD+VF+FRKVVLPDLAVLR VYEDTGKLIGQRVLPL+GLQ+GYRHISLRTEGNFPLSLPT+FC+++ TTY+PEGL DLVDALSDPRA+LSKEE+RMKQLA MGI++S+I DVP+TG + ++ + L++ SG + + VS+ ++ KKDDKKD+PKFD IS+ LL+TDK +QKLIK+Q +ELE L+K+ EKD+ + ++ TI+TDKLN +HA+E + S R I+ N ++ +E+ +NQM +LV+ HTD+W+++K KE +DL +SF ++R++LL+K+MKEVQE+QK+EL+IIQ+RE+KEMKAQQTKASI+++++V+NDRKL+NKAERDRRIRELND NTKRFIDQRK QAQ+ D+QTQELN++H E+E+V+ I KER K++EDLLA KRAT I
Sbjct: 1 MTSDIAKRQRTVPSAKAFEFIWKRPVPEVLQSGEHFDRYDEEAGILEPNCFVRVDKDGFFIYWQSENNDSQQLELSQISDVRSGTKPKDEKLTAQIQER-SGKSWDRIVTICSGLDLVNINYTHMVAKDVETASFWIQSLRSLTHNTKAANVCPMTQLRKHWLRLTLTVNARNRIPVRVIMKTFASGRNERIVYQSLKDLNLPHGKNDDIDPNEFPFEKFYELYHKICPRTDIEDLFKSLSKGKNHIHADKMIEFLNETQRDPRLNEILYPFANKQTIKYIQENYETQEEFKNTDEISIECFYRYLMSDDNACVFLDKLDIYQDMDQPLSHYYINSSHNTYLIGRQFGGKSSVEIYRQVLLAGCRCIELDCWDGRGEDQEPIITHGKAMCSDILFKDVIYAIRDTAFVASDCPVIMSFENHCSKQQQYKLAKYCEEILGDMLLTKPLDNYPLEPGVPLPPPEKLKRKILIKNKRLKPEAEKQQLELFLKGQTDAIQEENEVTEDPDLTIDRDDGDGVPGNKPNNGDLSSTTIGGGGSDTTISLSTIPTPQTLSTCTSSAELKRLQLKKEE-----------GNLTAEEEQIMMAHYHYTGATSSIHPLLSSFINYAQPVKFQGFDVAEDENIHHHMSSFSETMALGLLKNQAIEFVNYNKRQMSRIYPRGNRVDSSNYMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNCGYLLKPEFMRRPERQFDPFSESPMDGVIAATCEVKIISGQFLSDRKVGTYVEVDMYGLPTDTIRKEFRTRVVPNNGLNPVYGDDAVFVFRKVVLPDLAVLRFAVYEDTGKLIGQRVLPLDGLQAGYRHISLRTEGNFPLSLPTLFCQVSLTTYVPEGLNDLVDALSDPRAFLSKEEQRMKQLASMGIDSSEIADVPSTGNAKRVGGVVGGSGTSGQLSGSALSSVSGSGDVANVSS-----NSTKKDDKKDDPKFDPISISLLQTDKIYQKLIKKQAKELEILQKRQEKDAVTMLRNHTIITDKLNTSHAKE-------RSSTKRSINKEN------------GQNAALEDTHRNQMCELVRQHTDQWSNLKSTQMKEVYDLVLSFFDTRKDLLVKIMKEVQEEQKRELRIIQDREVKEMKAQQTKASIESSRSVMNDRKLRNKAERDRRIRELNDYNTKRFIDQRKLQAQRHDKQTQELNKRHALDEQEIVNGIKKEREEFMRKYEEDLLALKRATVI 1198
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. TrEMBL
Match: A0A5K4F0P8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 1575.07 bits (4077), Expect = 0.000e+0 Identity = 814/1255 (64.86%), Postives = 983/1255 (78.33%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDG-PMNEIN-----------------PTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTG--------KPFKKPPDKKSENSNQEPLTPN-LANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPS+KAFEF W++PV + L G HFDRYDE++ LE NC VRVD+ GFF++W+SE + Q L+LSQ+SDVR G+KPK++K+ A + E+ S DRIVTICSG DLVNI+YTHMV++D E A+FWI +LR LTHNTK NVCPM QL+KHWLRL L + A IPVR I KTFASG+ E+I++QSLK+L LP GK+D+IDP+ F FEKFYELYHKICPRTDIE++FK LSN K I +K+IE+LNE QRDPRLNEIL+PFANK T+KYI +N E EE++ ++SIECFYRYLMSDDNA VFLD+L+I QDMDQPL+HYYINSSHNTYL GRQFGGKSSVE+YRQVLL+GCRCIELDCWDG+GEDQEPIITHGKAMCTDILFKDVIYAIRDTAFV S+ P+I+SFENHCSK QQYKLAKYCE++LGD+LLTKP+D + L V LP P KL++KILIKNKRLKPE EKQQL++FLKGQT+ IQEENE EDPD + D DG N+ N ++ +T P P++ + LK +L +K KEE G+LTAEEEQ M+A YHY GAT++IHP LS+ VNY QPVKFQGFD+AED NIH+HMSSF+E V LGL++ I V+YNKRQ+SRIYPRGNRVDS+N+MPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGN GYLLKPEFMRRPER FDPFSESPMDGVIAAT E+KIISGQFLSD+KVGTYVEVDMYGLPTDT RKEFRTRVVPNNGLNP+YGDD+VF+FRKVVLPDLAVLR VYEDTGKLIGQRVLPL+GLQ+GYRHISLRTEGNFPLSLPT+FC+++ TTY+PEGL DLVDALSDPRA+LSKEE+RMKQLA MGI++S+I DVP+TG L+ + ++N SG S VS ++ KKD+KKD+PKFD IS+ LL+TDK +QKLIK+Q +ELE L+K+ EKD+ + ++ TI+TDKLN +HA+E + S R ++ N ++ +++ NQM +LV+ HTD+W+S+K KE ++L +SF +SR+ELL+K+MKEVQE+QK+EL+IIQ+RE+KEMKAQQTKASI++N++V+NDRKL+NKAERDRRIRELND NTKRFIDQRK QAQ+ D+QTQELN+ H E+E+++ I KER K++EDLLA KRAT I
Sbjct: 1 MTSDIAKRQRTVPSAKAFEFIWKRPVPEVLQTGEHFDRYDEETGILEPNCFVRVDKDGFFIYWQSENNDSQQLELSQISDVRSGAKPKDEKLTAQIQEK-SGKSWDRIVTICSGLDLVNINYTHMVAKDAETASFWIQSLRSLTHNTKAANVCPMTQLRKHWLRLTLTLNARNRIPVRVIMKTFASGRNERIVYQSLKDLNLPHGKNDDIDPNEFPFEKFYELYHKICPRTDIEDLFKSLSNGKSHIHADKMIEFLNETQRDPRLNEILYPFANKQTIKYIQENYETQEEFKNTDEVSIECFYRYLMSDDNACVFLDKLDIYQDMDQPLSHYYINSSHNTYLIGRQFGGKSSVEMYRQVLLAGCRCIELDCWDGRGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVASDCPVIMSFENHCSKHQQYKLAKYCEEILGDMLLTKPLDNYALEPGVALPPPEKLKRKILIKNKRLKPEAEKQQLDLFLKGQTDAIQEENEVTEDPDLTIDRDDGDGCSANKANNGEITATTTTTTGSGGGGDTVIPLNTTPTPQLVSCTSSAELK-------RLQLK-KEE------------GNLTAEEEQIMMAHYHYTGATSSIHPLLSSFVNYAQPVKFQGFDVAEDENIHHHMSSFSETVALGLLKNQAIEFVNYNKRQMSRIYPRGNRVDSSNYMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNCGYLLKPEFMRRPERQFDPFSESPMDGVIAATCEVKIISGQFLSDRKVGTYVEVDMYGLPTDTIRKEFRTRVVPNNGLNPVYGDDAVFVFRKVVLPDLAVLRFAVYEDTGKLIGQRVLPLDGLQAGYRHISLRTEGNFPLSLPTLFCQVSLTTYVPEGLNDLVDALSDPRAFLSKEEQRMKQLASMGIDSSEIADVPSTGGGGNAKRVGGGAGGGSSGGLGGTSGQLSGSVMSNISGSGETSNVS-----LNSTKKDEKKDDPKFDPISITLLQTDKMYQKLIKKQAKELEILQKRQEKDAVSMLRNHTIITDKLNTSHAKE-------RSSTKRTVNKEN------------GQNAALQDTHHNQMCELVRQHTDQWSSLKSTQMKEVYELVLSFFDSRKELLIKIMKEVQEEQKRELRIIQDREVKEMKAQQTKASIESNRSVMNDRKLRNKAERDRRIRELNDYNTKRFIDQRKLQAQRHDKQTQELNKHHTLDEQEIINGIKKEREEFIRKYEEDLLALKRATVI 1210
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. TrEMBL
Match: A0A0R3U5L3 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS2018 PE=4 SV=2) HSP 1 Score: 1568.52 bits (4060), Expect = 0.000e+0 Identity = 804/1305 (61.61%), Postives = 986/1305 (75.56%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISN---PLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQ---------------------------LADMGIETSDIVDVPTT----GKPFKKPP-------DKKSENSNQEPLTPNL-----ANKSG-------------QSNNSTVSTPV--------VGFSNNXXX----------XXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
M+SDIAKRQRTVPSSKA++F WR+PV L G +FDR+DE++ +LE C +RVDE GFF+ WKS+ EGQVL+LSQVSDVR G KPK++K+ A L ER+S+ LD+ IVT+CSG DLVNISYT+ V+ E+A+ WI ++R LTHNTK NVCPM QL+KHWLRL L V G IPVR ++KTFASG+ E+IIFQSLKELGLP GK+DE++PS FTFE+FYELYHKICPRTDIEE+FK LSN K+ +T EK+IE+LNEVQRDPRLNEIL+P+AN+ T++YI + E +E LS++ FYRYLMSDDNAPVFLDRL+ICQDMDQPL HYYINSSHNTYL GRQFGGKSSVEIYRQVLL+GCRCIELDCWDGKGEDQEPIITHGKAMC+DILFKDVIYA+RDTAFVTS+ P+I+SFENHCSK QQYKLAKYCED+LGD+LLTKP+DK+ L VPLPSP KL++KILIKNKRL+P+VEK QLE+F+KGQ + +QE+++ AEDPDP+V D + GPMN D DPHPE +G + V S + + + E + ++ +KKGSLTAEEEQAMLAQYHY GAT IHP LS+MVNY QPVKFQGFD+AED N+HYHMSSF+E V LGL++ + I V+YNKRQ+SRIYPRGNRV+S+N+MPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGN GYLLKPEFMRRPER FDPFSESPMDGVIAAT E++IISGQFLSD+KVGTYVEVDMYGLPTDT RKEFRTRVVPNNGLNP+YG+D+VF+FRKVVLPDLAVLR VYEDTGKLIGQRVLPL+GLQSGYRHISLRTEGNFPLSLPT+FC+++ TTY+PEGL DLVDALSDPRA+LSKEE+RMKQ LA MGI++S+I DVPT+ K+ P + S NS L + A+ +G +S STV +P VG S K ++PKF ISL +L +DK ++KL+K+Q +ELE L+++HEK++A + ++ T++TDKLN++HA+ I S +K++ N ++E QM DLV+ TDEW+ +K E H L ++F+++R++LLLK++++ ++QK+ LK IQERE K+MKAQQ K S+D+N+NV+ND +LKNKAERDRRIREL D NTKRFIDQRKAQAQ+ DRQ Q+L R+H+E+E V++ ++ ER L ++E+LLATKR T I
Sbjct: 1 MSSDIAKRQRTVPSSKAYDFVWRRPVPAALREGTYFDRFDEETGTLELGCFLRVDEDGFFLFWKSDVNEGQVLELSQVSDVRHGMKPKDEKLVATLTERVSSIGKNLDEHIVTVCSGLDLVNISYTNFVATSPEVASLWIQSVRGLTHNTKAQNVCPMTQLRKHWLRLTLTVNPRGKIPVRVVTKTFASGRNERIIFQSLKELGLPSGKNDEVEPSEFTFERFYELYHKICPRTDIEELFKTLSNGKETLTIEKMIEFLNEVQRDPRLNEILYPYANRQTIRYIQETYESRDENTSSDTLSLKGFYRYLMSDDNAPVFLDRLDICQDMDQPLCHYYINSSHNTYLIGRQFGGKSSVEIYRQVLLAGCRCIELDCWDGKGEDQEPIITHGKAMCSDILFKDVIYAVRDTAFVTSDYPLIMSFENHCSKHQQYKLAKYCEDILGDMLLTKPLDKYPLEAGVPLPSPEKLKRKILIKNKRLEPDVEKHQLELFMKGQADPVQEDDDVAEDPDPVVTPDCDVGPMN---------GDIDPHPETKLRPGSGQINVLSTSLPLSSSLIGKLSETEMKRLITKKGSLTAEEEQAMLAQYHYTGATKTIHPLLSSMVNYAQPVKFQGFDVAEDENVHYHMSSFSETVALGLMKNEAIEFVNYNKRQMSRIYPRGNRVESSNYMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNCGYLLKPEFMRRPERQFDPFSESPMDGVIAATCEVRIISGQFLSDRKVGTYVEVDMYGLPTDTIRKEFRTRVVPNNGLNPVYGEDAVFVFRKVVLPDLAVLRFAVYEDTGKLIGQRVLPLDGLQSGYRHISLRTEGNFPLSLPTLFCRVSLTTYVPEGLNDLVDALSDPRAFLSKEEQRMKQVGILLEPVALLLLHMFTIPISVTSHLKLASMGIDSSEIDDVPTSSTKLAAMLKQRPMGMGNLSNAPSANSAAGLLPSGVGSVAAASSAGLTLPGVGASADHQKSTGSTVVSPSANPLTSGGVGVSGATSGPSANSAKKEDKKAEDPKFPPISLSMLRSDKNYRKLVKKQAKELEALQRRHEKEAAAMLRAHTLLTDKLNSSHAKAIASSTSSLRSTPQKMNGINT---------------PMKEAHIAQMNDLVRQQTDEWSKLKYTQMNEIHGLVLTFMDARKDLLLKILRDAHDEQKRLLKQIQERENKDMKAQQIKISLDSNRNVMNDPRLKNKAERDRRIRELKDYNTKRFIDQRKAQAQRNDRQVQDLLRRHEEEEHGVIAGVNLERDDLIRSYREELLATKRTTMI 1281
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. TrEMBL
Match: A0A074ZXA5 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase OS=Opisthorchis viverrini OX=6198 GN=T265_05106 PE=4 SV=1) HSP 1 Score: 1563.9 bits (4048), Expect = 0.000e+0 Identity = 794/1228 (64.66%), Postives = 970/1228 (78.99%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPS+KAFEFNWR+PV D L NGA FDR DE++ +LE++C VRVD GFF++WK+E + Q+L+LSQ+SDVR GSKPKE+K+ A + ER DRIVTICSG DLVNI YTHM++ + E A +WI LR LTHNTK NVCPM QL+KHW+RL L V IPVR I KTFASG+ E+++FQSLKELGLP GK+D I+P++F FEKFYELYHKICPRTDIE++FK LSN+ D + +K+IE+LNE QRDPRLNEIL+PFAN+ T+KYI +N E EEY+ LSIECFYRYLMSD+NA VFLDRL++ Q+MDQPL+HYYINSSHNTYL+GRQFGGKSSVE+YRQVLL+GCRCIELDCWDG+GEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSE P+I+SFENHCSK QQYKLAKYCED+LGD+LLTKPID L PLP P KL++KILIKNKRLKPE EKQQLE+FLKGQT+ IQEEN+ AEDPD V VDG+ G + P+ + E LNG + S+T D ++ KKG+LTAEEEQ M+ QY + GAT++IHP LS+ +NY QPVKFQGFD+AE+ N+H+HMSSF+E + LGL++ I V+YNKRQ+SRIYPRGNRVDS+N+MPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGN GYLLKPEFMRR ER FDPFSESPMDGVIAAT E+KIISGQFLSD+KVGTYVEVDMYGLPTDT RKEFRTRVVPNNGLNP+YG+D+VF+FRKVVLPDLAVLR VYE+TGKLIGQRV+PL+GLQ+GYRHISLRTEGNFPLSLPT+FC++ TTY+PEGL DLVDALSDPRA+LSKEE+RMKQLA MGI++S+I DVPTT + + T ++G ++ + KKD+PKFD ISL LL+TDK +QKL+K+Q++ELE ++++ +KD+ + ++ T+VTDKLN HA+E + S R N +S ++E QK+Q+ +L++ D+WT++K+ KE DL + ++E R+ELLL++MKEVQE+QK+EL+I+QERE+KEM+AQQTKASI+++++V+NDRKLKNKAERDRRIRELND NTKRFIDQRK QAQ+QD+QTQELN++H ++EK+V+ A+ KE+ K++EDLLA KR+T I
Sbjct: 1 MTSDIAKRQRTVPSAKAFEFNWRRPVPDVLQNGAFFDRLDEETGTLETDCFVRVDPDGFFIYWKTENSDSQLLELSQISDVRAGSKPKEEKLIAQIQERGPGKSWDRIVTICSGLDLVNIIYTHMIAPEPETAAYWIQQLRSLTHNTKAVNVCPMTQLRKHWIRLTLSVNPKNKIPVRVIMKTFASGRNERVVFQSLKELGLPHGKNDVIEPAAFPFEKFYELYHKICPRTDIEDLFKSLSNNTDVLHADKMIEFLNETQRDPRLNEILYPFANRQTIKYIQENYETQEEYKNTDMLSIECFYRYLMSDNNACVFLDRLDVYQEMDQPLSHYYINSSHNTYLSGRQFGGKSSVEMYRQVLLAGCRCIELDCWDGRGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEYPVIMSFENHCSKHQQYKLAKYCEDILGDMLLTKPIDGFPLEPGAPLPPPEKLKRKILIKNKRLKPEAEKQQLELFLKGQTDAIQEENDIAEDPDLTVDVDGKFGSLLLHEPSA-----RSCYSESGTKGLNGESGLSSSSNTPAP-PSGGSSSADLKRLQMKKGNLTAEEEQMMMVQYQHTGATSSIHPLLSSFINYVQPVKFQGFDVAEEKNLHFHMSSFSETISLGLMKNQAIEYVNYNKRQMSRIYPRGNRVDSSNYMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNCGYLLKPEFMRRLERQFDPFSESPMDGVIAATCEVKIISGQFLSDRKVGTYVEVDMYGLPTDTIRKEFRTRVVPNNGLNPVYGEDAVFVFRKVVLPDLAVLRFAVYEETGKLIGQRVIPLDGLQAGYRHISLRTEGNFPLSLPTLFCQVNLTTYVPEGLNDLVDALSDPRAFLSKEEQRMKQLASMGIDSSEIADVPTTTAKRTPASGAAAASGPPGAAT-----EAGDASGAKKEE------------KKDDPKFDPISLSLLQTDKNYQKLLKKQSKELELVQRRQDKDATAMLRNHTVVTDKLNTTHAKE-------RSSTKRPSKKEN------------GQSSVLEATQKSQLCELMRQQADQWTNLKVAQMKEICDLVLGYIEVRKELLLRIMKEVQEEQKRELRIVQEREVKEMRAQQTKASIESSRSVMNDRKLKNKAERDRRIRELNDYNTKRFIDQRKIQAQRQDKQTQELNKRHAQEEKDVIDAMHKEKDDFIRKYEEDLLAVKRSTVI 1186
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Cavefish
Match: PLCB4 (phospholipase C beta 4 [Source:NCBI gene;Acc:103022380]) HSP 1 Score: 1242.25 bits (3213), Expect = 0.000e+0 Identity = 657/1197 (54.89%), Postives = 847/1197 (70.76%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNP--LDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLK----GQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNAS-----KKGSLT---AEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ 3695
+K++EFNW++ V D L GA FDR DED ES+CL +VDE+GFF+ WKSE EGQVL+ S ++ VR G+ PK+ KI + L N L+ I+ +CSG DLVN+S+ +MV+ + + A W+ L+ + HN K NNVCPM LKKHW+RL NG IPVR I++TF SGKTEK IFQ+LKELGLP GK+DEID S FTF+ FY L KICPRTDIEE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + V I++ E E+ +K+G++S + F RYLMSD+NAPVFLDRL++CQDMDQPLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLLSGCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSKPQQYK+AKYCED+ G+LLL +P++ + A PLPSP L++KILIKNKRLKPEVE++QLE F + G+ + ++EN ED E+ E+N + +N T P T+ N + K K D I E + AS KKG A+ EQ ++A Y Y GATTNIHPYLSAMVNY QPVKFQ F+IAE+ NIH++MSSFNE+VGLG ++ + I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG GYL KP+FMRR +R FDPFSE+P+DGVIAAT +++ SGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP Y ++ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPT+FC I TY+P+G +VDALSDP+ +LS EKR Q+ +GIETSDI DVP K K N + +TP ++ GQ++ +T NN + KKD + +++ L+ K++ KLIK+Q +EL L+K+H KD + KS DK+ A H +E K+ ++K NC LK++ + + + K ++ D+V HT EW+ M H EE ++ + + + E L K++ VQE Q +LK++ ER+ KEMKA Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+++RK A K ++ ++L + EQ
Sbjct: 2 TKSYEFNWQKHVPDFLQEGAVFDRLDEDPFVFESSCLFKVDEFGFFLTWKSEGKEGQVLECSLINSVRVGAVPKDPKILSSLEAAGKNEADLEGCIICVCSGPDLVNLSFMYMVADNADTAKKWLEGLKSVIHNFKANNVCPMTCLKKHWMRLSFLTNVNGKIPVRGITRTFGSGKTEKGIFQALKELGLPSGKNDEIDHSMFTFDVFYALTQKICPRTDIEELFKKINGDKTDYLTVDQLVSFLNENQRDPRLNEILFPFYDPKRVMQIIEKYERDEDLKKKGRMSSDGFCRYLMSDENAPVFLDRLDMCQDMDQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKPQQYKMAKYCEDIFGELLLKQPLEGFPIEPARPLPSPNDLKRKILIKNKRLKPEVEQKQLESFKRHMEAGEMSVQGGDDENEED--------MENADSKEVNSDMKTRN-TSEEPSEQDTQENSVKKDKIPDDEITEISEATEADVTDLSEASDLDNKKKGGDAPEDADAEQQLIASYKYEGATTNIHPYLSAMVNYAQPVKFQSFEIAEEKNIHHNMSSFNESVGLGYLKTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGACGYLQKPDFMRRSDRMFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPAYNEEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGAIVDALSDPKKFLSIAEKRADQMRALGIETSDIADVPNES---SKNDKKGKVNQVKANVTPQTSSDMGQTSTAT--------QNNSSETKKDSALVNQVTIEDLKQMKSYVKLIKKQQKELNALKKRHAKDHNAMQKSHCTQVDKMVAQHDKEKFTLEKLLEKAIKKRGENNC---SELKKETAIKVENLTTDHKAKVKDIVAQHTKEWSEMINSHSTEEQEMKDAHVTQQCEHLKKLLSSVQEQQTMQLKLVHERQSKEMKANQAKTSMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKHSKELEQLQKSQREQ 1174
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Cavefish
Match: PLCB4 (phospholipase C beta 4 [Source:NCBI gene;Acc:103022380]) HSP 1 Score: 1241.87 bits (3212), Expect = 0.000e+0 Identity = 662/1228 (53.91%), Postives = 858/1228 (69.87%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNP--LDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLK----GQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNAS-----KKGSLT---AEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATA 3788
+K++EFNW++ V D L GA FDR DED ES+CL +VDE+GFF+ WKSE EGQVL+ S ++ VR G+ PK+ KI + L N L+ I+ +CSG DLVN+S+ +MV+ + + A W+ L+ + HN K NNVCPM LKKHW+RL NG IPVR I++TF SGKTEK IFQ+LKELGLP GK+DEID S FTF+ FY L KICPRTDIEE+FK+++ K D++T ++++ +LNE QRDPRLNEILFPF + V I++ E E+ +K+G++S + F RYLMSD+NAPVFLDRL++CQDMDQPLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLLSGCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTSE P+ILSFENHCSKPQQYK+AKYCED+ G+LLL +P++ + A PLPSP L++KILIKNKRLKPEVE++QLE F + G+ + ++EN ED E+ E+N + +N T P T+ N + K K D I E + AS KKG A+ EQ ++A Y Y GATTNIHPYLSAMVNY QPVKFQ F+IAE+ NIH++MSSFNE+VGLG ++ + I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG GYL KP+FMRR +R FDPFSE+P+DGVIAAT +++ SGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP Y ++ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPT+FC I TY+P+G +VDALSDP+ +LS EKR Q+ +GIETSDI DVP K K N + +TP ++ GQ++ +T NN + KKD + +++ L+ K++ KLIK+Q +EL L+K+H KD + KS DK+ A H +E K+ ++K NC LK++ + + + K ++ D+V HT EW+ M H EE ++ + + + E L K++ VQE Q +LK++ ER+ KEMKA Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+++R + L KH ++ +++ + ++ LE KF E LL + A +
Sbjct: 2 TKSYEFNWQKHVPDFLQEGAVFDRLDEDPFVFESSCLFKVDEFGFFLTWKSEGKEGQVLECSLINSVRVGAVPKDPKILSSLEAAGKNEADLEGCIICVCSGPDLVNLSFMYMVADNADTAKKWLEGLKSVIHNFKANNVCPMTCLKKHWMRLSFLTNVNGKIPVRGITRTFGSGKTEKGIFQALKELGLPSGKNDEIDHSMFTFDVFYALTQKICPRTDIEELFKKINGDKTDYLTVDQLVSFLNENQRDPRLNEILFPFYDPKRVMQIIEKYERDEDLKKKGRMSSDGFCRYLMSDENAPVFLDRLDMCQDMDQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKPQQYKMAKYCEDIFGELLLKQPLEGFPIEPARPLPSPNDLKRKILIKNKRLKPEVEQKQLESFKRHMEAGEMSVQGGDDENEEDM--------ENADSKEVNSDMKTRN-TSEEPSEQDTQENSVKKDKIPDDEITEISEATEADVTDLSEASDLDNKKKGGDAPEDADAEQQLIASYKYEGATTNIHPYLSAMVNYAQPVKFQSFEIAEEKNIHHNMSSFNESVGLGYLKTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGACGYLQKPDFMRRSDRMFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPAYNEEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGAIVDALSDPKKFLSIAEKRADQMRALGIETSDIADVPNES---SKNDKKGKVNQVKANVTPQTSSDMGQTSTAT--------QNNSSETKKDSALVNQVTIEDLKQMKSYVKLIKKQQKELNALKKRHAKDHNAMQKSHCTQVDKMVAQHDKEKFTLEKLLEKAIKKRGENNC---SELKKETAIKVENLTTDHKAKVKDIVAQHTKEWSEMINSHSTEEQEMKDAHVTQQCEHLKKLLSSVQEQQTMQLKLVHERQSKEMKANQAKTSMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEER-----------KRLAMKHSKELEQLQKSQREQLEKLE-KFNEQLLKSHHANS 1193
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Cavefish
Match: PLCB4 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [Source:NCBI gene;Acc:103033015]) HSP 1 Score: 1189.1 bits (3075), Expect = 0.000e+0 Identity = 632/1193 (52.98%), Postives = 820/1193 (68.73%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLK----GQTEII--QEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTP--NLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ 3695
+KA+EFNW++ V D L GA+FDR+DED + ESNC RVD +GFF+ WKSE EGQVL+ S ++ +R S PK+ KI + L + + L+ RI+ ICSG DLVN+S+ ++V+QD IA W ++LR L HN++ NNVCPM L+KHW+RL NG IPVRSI++TFASGKTEK+IFQ+LK+LGLP GK+DE++P +FTFEKFY L KICPRTDIE +FK+L K DF+ T++++ +LNE QRDPRLNEILFPF + + I+++ E E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MDQPLAHY+I+SSHNTYLTGRQFGG+SSVE+YRQVLLSGCRC+ELDCWDGKGEDQEPIITHGKAMCTD+LFKDVI AI +TAFV+SE P+ILSFENHCS+ QQYKLA+YCED+ GD LL +P+D L PLPSP L++KILIKN+RLKPEVEK+QLE F K G + E+EN ED +VD E +P I + ++ K + L + + E ++N K +EQA++ Y Y+ ATTNIHPYLS ++NY Q VKF GF+ AE+ NIH++MSSFNE+VGLG +R + I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPT+FC I TY+P+G +VDALSDP+ +LS EKR Q+ MGIET +I DVP KK + + + L+P +L +S S + + P K + +++ L+ K + KL K+Q +EL L+KK K L +S DK+ H +E K +K+S NC + + + I K ++ D H EW M H E +L + + E L K+M QE Q ++L + ER+ KEM+A Q K+S+ + + D+ +KNKAER+RR+RELN NT++F+ +RK A Q ++ ++L EQ
Sbjct: 2 AKAYEFNWQRAVPDCLQEGAYFDRFDEDPFAFESNCFFRVDAFGFFITWKSEGKEGQVLECSLINSIRSTSVPKDPKILSALEATGKTESDLEGRIICICSGADLVNLSFMYIVAQDISIAKQWTDSLRSLIHNSRANNVCPMTCLRKHWMRLSFLTNVNGKIPVRSITRTFASGKTEKVIFQALKDLGLPSGKNDELEPDAFTFEKFYSLSQKICPRTDIEVLFKKLCGEKSDFLNTDQLVSFLNENQRDPRLNEILFPFYDSKRARQIIESYETDEKLQKKGLMSCDGFSRYLMSDENAPVFLDRLELYQEMDQPLAHYFISSSHNTYLTGRQFGGRSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDVLFKDVIQAIEETAFVSSEFPVILSFENHCSRHQQYKLARYCEDIFGDTLLRQPLDDFPLEPGQPLPSPNDLKRKILIKNRRLKPEVEKKQLEHFRKHMEAGDVNMSTNMSEDENEEDAGCADLVD-------EAHPERICGRLVISQTNSSEGDVPAADKGNKDEVAGLEVLAQTPLEAACQENGKKACEPGVADEQALIQSYTYVAATTNIHPYLSNIINYAQAVKFLGFEEAEETNIHHNMSSFNESVGLGYLRTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRMFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGAIVDALSDPKKFLSICEKRTDQMRAMGIETWEIADVPNDS----CKRSKKGKANQVKSLSPQRSLETRSTSSGQNASTFP----------KKDTDTTMPQVTVEDLKQMKEYLKLAKKQVKELNALKKKQTKAHTALQRSHCTQMDKVVVQHEKEKRVLEKQLEKNKKKVSESNCC---EMGREIEMKMKTITADHKTKVKDAAAAHAREWAEMMKAHSAEIQELRDQHVLQQCEQLRKLMLMTQEQQTQQLTHLHERQCKEMRANQAKSSMANGRAISQDKSIKNKAERERRVRELNSNNTRKFLTERKRLAMGQSKEIEQLQTAQHEQ 1169
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Cavefish
Match: PLCB4 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [Source:NCBI gene;Acc:103033015]) HSP 1 Score: 1157.51 bits (2993), Expect = 0.000e+0 Identity = 619/1193 (51.89%), Postives = 807/1193 (67.64%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKG--------QTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTP--NLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ 3695
+KA+EFNW++ V D L GA+FDR+DED + ESNC RVD +GFF+ WKSE + ++L + + + + L+ RI+ ICSG DLVN+S+ ++V+QD IA W ++LR L HN++ NNVCPM L+KHW+RL NG IPVRSI++TFASGKTEK+IFQ+LK+LGLP GK+DE++P +FTFEKFY L KICPRTDIE +FK+L K DF+ T++++ +LNE QRDPRLNEILFPF + + I+++ E E+ +K+G +S + F RYLMSD+NAPVFLDRL + Q+MDQPLAHY+I+SSHNTYLTGRQFGG+SSVE+YRQVLLSGCRC+ELDCWDGKGEDQEPIITHGKAMCTD+LFKDVI AI +TAFV+SE P+ILSFENHCS+ QQYKLA+YCED+ GD LL +P+D L PLPSP L++KILIKN+RLKPEVEK+QLE F K T + ++ENE D +VD E +P I + ++ K + L + + E ++N K +EQA++ Y Y+ ATTNIHPYLS ++NY Q VKF GF+ AE+ NIH++MSSFNE+VGLG +R + I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG+ GYLLKP+FMRRP+R FDPFSE+P+DGVIAAT +++ISGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP+Y ++ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPT+FC I TY+P+G +VDALSDP+ +LS EKR Q+ MGIET +I DVP KK + + + L+P +L +S S + + P K + +++ L+ K + KL K+Q +EL L+KK K L +S DK+ H +E K +K+S NC + + + I K ++ D H EW M H E +L + + E L K+M QE Q ++L + ER+ KEM+A Q K+S+ + + D+ +KNKAER+RR+RELN NT++F+ +RK A Q ++ ++L EQ
Sbjct: 2 AKAYEFNWQRAVPDCLQEGAYFDRFDEDPFAFESNCFFRVDAFGFFITWKSEGKDPKILSALEATG------------------KTESDLEGRIICICSGADLVNLSFMYIVAQDISIAKQWTDSLRSLIHNSRANNVCPMTCLRKHWMRLSFLTNVNGKIPVRSITRTFASGKTEKVIFQALKDLGLPSGKNDELEPDAFTFEKFYSLSQKICPRTDIEVLFKKLCGEKSDFLNTDQLVSFLNENQRDPRLNEILFPFYDSKRARQIIESYETDEKLQKKGLMSCDGFSRYLMSDENAPVFLDRLELYQEMDQPLAHYFISSSHNTYLTGRQFGGRSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDVLFKDVIQAIEETAFVSSEFPVILSFENHCSRHQQYKLARYCEDIFGDTLLRQPLDDFPLEPGQPLPSPNDLKRKILIKNRRLKPEVEKKQLEHFRKHMEAGDVNMSTNMSEDENEEDAGCD---LVD-------EAHPERICGRLVISQTNSSEGDVPAADKGNKDEVAGLEVLAQTPLEAACQENGKKACEPGVADEQALIQSYTYVAATTNIHPYLSNIINYAQAVKFLGFEEAEETNIHHNMSSFNESVGLGYLRTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRMFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGAIVDALSDPKKFLSICEKRTDQMRAMGIETWEIADVPNDS----CKRSKKGKANQVKSLSPQRSLETRSTSSGQNASTFP----------KKDTDTTMPQVTVEDLKQMKEYLKLAKKQVKELNALKKKQTKAHTALQRSHCTQMDKVVVQHEKEKRVLEKQLEKNKKKVSESNCC---EMGREIEMKMKTITADHKTKVKDAAAAHAREWAEMMKAHSAEIQELRDQHVLQQCEQLRKLMLMTQEQQTQQLTHLHERQCKEMRANQAKSSMANGRAISQDKSIKNKAERERRVRELNSNNTRKFLTERKRLAMGQSKEIEQLQTAQHEQ 1148
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Cavefish
Match: plcb3 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [Source:NCBI gene;Acc:103029357]) HSP 1 Score: 654.825 bits (1688), Expect = 0.000e+0 Identity = 423/1157 (36.56%), Postives = 659/1157 (56.96%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCL-VRVDEYGFFVHWKSEQG-EGQVLDLSQVSDVRFGSKPKEDKICAVL----LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHC-SKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAED-PDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDP-RAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR---EINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIE--EVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQERE-----IKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRE 3593
V + L G+ F ++DE+ +S + + ++VD YGFF++W E +++D+S + D R G K K V + ++ ++VT+ G DLVNIS+ + + +IA W L L N N L K + +L L V +G IPV++I K F+ + + +L++ GL ++D + FT++KF + +C R +I+ IF EL S K F++ +++++++N QRD RLNE+L+P ++ V+ +++ E + + ++S+ F +YL ++NA V +R ++ DM+QPL+HY+INSSHNTYLT Q G SSVE+YRQVLL+GCRCIELDCW G+ D+EPIITHG M T+I FK+VI AI ++AF TS P+ILSFENH S QQ K+A+YC + GD LL P++K+ L LPSP +L KILIKNK+ Q + ++ + AED PL D P+NE + I+ N + E + + + K ++ D + + +EE D +K+ S +G+ Y + AT +S +VNY +PVKF+ F++A N ++ MSSF E G+ ++ + I V+YNK+QLSRIYP+G RV+S+N+MPQ+FWN GCQMVALNFQT DL MQLN FEYNG+SGYLLKPEFMRR ++ FDPF+E+ +DG++A T++IKI+SGQFL+DKKVG YVEVDM+GLP DT RK FRT+ NN ++P++ DD F+F KVVLP LA LR+ ++E+ GK IG R+LP+ L+ GY +I+L+ + N PL L ++ YIP+ DAL++P + L + E+++ + + + V KP +P + + + V PV+ EP+ S+ L+ K+++KL+K+Q +EL+ LRKKH K L K Q +++LN++ R ++ KK+++ ++K + ++ + E ++ E Q ++++L K K H E + + Q + +K +KE+ + +KKEL+ I +R+ I+ K + KA ++ +N IN + +++ RR+ E
Sbjct: 18 VHEVLKRGSKFIKWDEEPSSGQPTLVTLKVDPYGFFLYWSGGGNMEVEIVDISHIRDTRTGKFAKLPKALTVRELLGFGKGEGNVEGKLVTVVHGNDLVNISFLNFQAMQEDIAKVWTEELFKLATNILSQNSSRNTFLLKAYTKLTLQVTQDGKIPVKNILKMFSDKRR---VESALEQCGLVANRADGVKLDDFTWDKFQSFLNNLCMRPEIDRIFLELGSKGKPFLSLDQMLDFINRRQRDSRLNEVLYPPLKREQVRQLMEKYESNPSQLERDQISLMTFSKYLGGEENAVVPPERFDVMDDMNQPLSHYFINSSHNTYLTVGQLTGPSSVEMYRQVLLTGCRCIELDCWKGRPPDEEPIITHGFTMTTEIPFKEVIEAIAESAFKTSPYPVILSFENHVDSTRQQAKMAEYCRSIFGDALLIDPLEKYPLVPGQQLPSPQELMGKILIKNKKKHHHHHHQA-----TNGGSVRRKAGDGAEDQASPL-----NDCPLNEGEASQIISNGGEKLAERMSKD-SDIRKSIDRGDGESEEEEEEEPVADPKKHHSDEGT-----------AYSEVNATEE----MSTLVNYIEPVKFKSFELAAKRNKYFEMSSFVETKGMDSLKNNPIEFVEYNKKQLSRIYPKGTRVESSNYMPQLFWNVGCQMVALNFQTLDLPMQLNLSVFEYNGHSGYLLKPEFMRRTDKHFDPFTENIVDGIVANTVKIKIVSGQFLTDKKVGVYVEVDMFGLPADTKRK-FRTKTSNNNSMDPVW-DDEAFVFSKVVLPTLASLRVALFEENGKFIGHRILPVVALRPGYHYINLKNDLNQPLLLASLLVYTEVMDYIPDEHQGYADALTNPIKHVLDQRERQLAVFMEDNNDGNKRVQQDEGEKPEPRPV------AVVDFPSLPSPTPPPVEPEIPVPAPVI------------EPQ----SIEQLKQHKSYEKLLKKQNKELKELRKKHLKKVWALSKEQKTRSNQLNSDIQRRKSQVEKKLRLS---VKKNEPEGPVRTELNELVVELEKQTVQLREWQMQELLELRKKQYQLEKEKKFIHLGESYQKLKEVAQECQAVQIKKLKEICDKEKKELQKILDRKRQNSIIEARKGDKEKA--ESEQNEINRKHIQDSVNSYRRLDE 1116
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Sea Lamprey
Match: PLCB4 (phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059]) HSP 1 Score: 589.341 bits (1518), Expect = 0.000e+0 Identity = 302/582 (51.89%), Postives = 391/582 (67.18%), Query Frame = 3
Query: 1842 TAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVV--GFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDR 3581
+ E E A ++ Y Y G TTNIHPYLSA+VNY QPVKFQ F +AE+ NIHY+MSSFNE+VGLG ++ I LV+YNKRQ+SRIYPRG RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG G+LLKP+FMRRP+R+FDPFSE+P+DGVIA T +++ISGQFLSD++VGTYVEVDMYGLPTDT RKEFRTR+VPNNGLNP+Y + F+FRKV+LPDLAVLRI V++D+ KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPT+FC I TY+P+G D VDALSDP+ +LS+ EKR Q+ MGIE SDI DVP + + N+ TP S TPV NN DEP + + L K+F KL+K+Q +E+ L+K H K A L K+ T DK+ + + RE + +K + K +C + EK EE +E +K Q + + + R+EE + + EL+ ++ E Q ++L++ ER+ K+++ Q K S++ +K + DR +KNKAER+R
Sbjct: 1 SVESEDAWVSAYKYTGGTTNIHPYLSALVNYAQPVKFQNFVVAEERNIHYNMSSFNESVGLGYLKTGAIELVNYNKRQMSRIYPRGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGFCGFLLKPDFMRRPDRTFDPFSETPVDGVIAGTCSVQVISGQFLSDRQVGTYVEVDMYGLPTDTIRKEFRTRLVPNNGLNPLYNQEP-FVFRKVILPDLAVLRIAVFDDSNKLIGQRILPLDGLQTGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDFVDALSDPKRFLSQAEKRANQMQAMGIEASDIGDVP-----------ESRGSVNRGAATP---------QTSVTCTPVTVRSLGNNAIGSTPDEPLVPPVCVDTLRHSKSFLKLLKKQEKEMTLLKKAHAKAQASLQKTYTGQGDKVTSQYERERSSILKQTEKTLAKKGEGHCAGLQKETEKRVEEL-TVEHQRKTQALQAERAREQAALQAQQARRQEEARTAHA--AQQDELVRALLAGAHEQQIRQLQLTHERDTKQLEGTQAKQSMEESKLISQDRSIKNKAERER 558
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Sea Lamprey
Match: PLCB1 (phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917]) HSP 1 Score: 362.459 bits (929), Expect = 3.874e-107 Identity = 189/417 (45.32%), Postives = 261/417 (62.59%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADM---GIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNA 3155
+S +VNY QPVKF F+ A N Y MSSF E G+ + + + V+YNK QLSRIYP+G RVDS+N+MPQ+FWNAGCQ+VALN+QT DLAMQLN G FEYN SGY+LKPEFMRR ++ FDPFS++ +DG+IA T+ +K+ISGQFLSDKKVG +VEVDM+GLP DT RK ++T+ P N +NP++ D+ F+F+KVVLP LA LR+ +ED GK +G R++P+ ++ GYRHI LR E N L+LP I I Y+P+ DL +AL++P Y+S E+R +QLA + E + V + G P PP ++ P SG ++ TV +P + +++ ++ K KL +Q +E ++L K+H+K A L K Q L A
Sbjct: 512 MSNLVNYVQPVKFTTFEAARKKNRSYEMSSFVETKGMEQLTKCPVEFVEYNKCQLSRIYPKGTRVDSSNYMPQVFWNAGCQLVALNYQTMDLAMQLNIGMFEYNRRSGYILKPEFMRRSDKHFDPFSDNTVDGIIANTVSVKVISGQFLSDKKVGCFVEVDMFGLPVDTKRKIYKTKTAPGNSINPVW-DEEPFVFKKVVLPTLACLRVAAFEDGGKFLGHRIMPVSAIRPGYRHICLRNESNQALALPAILVYIQVKDYVPDAFADLTEALANPIRYVSLMEQRAQQLAALIGEFDEGTAEVRMAHDG-PISMPP-----APHKVAAPPGAPQGSGPTD--TVKSPAKPPPQKDDVLASILRGVEALTVEQIKQHKAVLKLQFKQHKEAKDLSKRHQKRIAELAKEQMARLSDLQA 919 HSP 2 Score: 315.849 bits (808), Expect = 1.111e-90 Identity = 151/355 (42.54%), Postives = 227/355 (63.94%), Query Frame = 3
Query: 417 LDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKP-QQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
L+ + VT+ G+D VN+++ + V+ EIA W + L N +N I L K + +L L + + IPV++I + FA+ + + + +L+ GLP G++D I P+ F + F ICPR +I+ IF E+ + S+ ++T ++ E++N QRDPRLNEIL+P V+ +++ EP+ K+G +S+ F ++L D+N+ + +++++ DM QPL+HY+INSSHNTYL Q G SSVE+YRQ LL+GCRC+ELDCW G+ D+EP+ITHG M T+ILFKDVI AI+D AF TS P+ILSFENH P QQ K+A+YC + GD LL P++K+ L +
Sbjct: 18 LEQKTVTVVFGSDFVNLTFLNFVAFSEEIAKEWATGIFQLASNLLYHNSSRDIFLDKLYTKLTLQLNQDSKIPVKNICRLFAADR--RRVETALESCGLPNGRNDAIYPAEFGPDVFRLFIKSICPRPEIDGIFAEVGARSRPYLTVDQFTEFINNCQRDPRLNEILYPPLKPSQVQLMIEKYEPNASLAKKGHISVGGFLKFLQGDENSAIPAEKIDLSDDMMQPLSHYFINSSHNTYLMAGQLAGSSSVEMYRQALLAGCRCVELDCWKGRTADEEPVITHGFTMTTEILFKDVIEAIKDCAFKTSPFPVILSFENHVDSPKQQAKMAEYCRTIFGDALLMDPLEKYLLESGI 370
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Sea Lamprey
Match: PLCB1 (phospholipase C beta 1 [Source:HGNC Symbol;Acc:HGNC:15917]) HSP 1 Score: 347.436 bits (890), Expect = 1.707e-100 Identity = 166/296 (56.08%), Postives = 215/296 (72.64%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVP-NNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIE 2798
+S +VNY QP+KF F+ A+ N +Y MSSF E+ G+ + + + V+YNK QLSRIYP+G RVDS+N+MPQ+FWNAGCQMVALN+QT DLAMQLN G FEYN SGYLLKPEFMRR ++ FDPF++ +DGVIA T+ +K+ISGQFLSD+KV TYVEVDM+GLP DT RK ++TR NN +NP++ +D F+F KVVLP LA LRIGV+E+ GK IG R+LP+ ++ G+ HI LR E N PLSLP IF I Y+P + + LS+P Y E+R KQL + ++
Sbjct: 510 MSNLVNYVQPIKFDSFEDAKKRNRNYEMSSFVESKGMEQLTKCPVEFVEYNKTQLSRIYPKGTRVDSSNYMPQVFWNAGCQMVALNYQTLDLAMQLNMGIFEYNCRSGYLLKPEFMRRADKQFDPFTQDIIDGVIANTISVKVISGQFLSDRKVSTYVEVDMFGLPVDTKRK-YKTRTSKDNNSINPVWEEDP-FVFDKVVLPSLASLRIGVFEEGGKFIGHRILPVSAIRPGFHHICLRNESNQPLSLPAIFVFIQVKDYVPVAFENFISGLSNPIMYQGLMEQRAKQLESLTMD 803 HSP 2 Score: 306.99 bits (785), Expect = 1.167e-86 Identity = 158/356 (44.38%), Postives = 220/356 (61.80%), Query Frame = 3
Query: 417 LDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL--SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKP-QQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
++ R +T+ G DLVNIS+ + + +A W + L L N N L K + +L L +PVRSI + F + K K + +L LP G++D I +FT+E FY +K+CPRTDI+ IF E + +T E+ +++N QRDPRLNE+LFP V+ ++D E S K+G++S+ F RYL ++N V ++L++ +DM QPL+HY+INSSHNTYLTG Q G SSVE+YRQ LL+GCRC+ELDCW G+ D++PIITHG M T+I FK+VI AI +TAF TS P++LSFENH P QQ K+A+YC + GD LL +DK+ L V
Sbjct: 19 MESRTITVVHGPDLVNISFLNFTALTESVAKVWTDELFTLATNLLAQNSSRDKFLNKAYTKLKLQSNTEDKVPVRSILRMFPTDK--KKVENALMSCELPSGRNDNIPIETFTYEAFYSFVNKLCPRTDIDSIFAERYGGQASAXMTVEQFTDFINSKQRDPRLNEVLFPPMKTHQVQALIDKFE-STNLAKKGQISVLGFLRYLNGEENGIVPPEKLDLNEDMTQPLSHYFINSSHNTYLTGGQLKGNSSVEMYRQSLLAGCRCVELDCWKGRTADEDPIITHGFTMTTEIPFKEVIDAIAETAFKTSPYPVVLSFENHVDSPKQQAKMAEYCRLMFGDALLVDVLDKYPLESGV 371
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Sea Lamprey
Match: plcd3b (phospholipase C, delta 3b [Source:ZFIN;Acc:ZDB-GENE-081222-2]) HSP 1 Score: 181.415 bits (459), Expect = 2.929e-47 Identity = 92/244 (37.70%), Postives = 140/244 (57.38%), Query Frame = 3
Query: 717 FGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPI 1448
F +SD ++F +L+ K+ R D+ +FK LS + ++ ++L + Q + ++ I+ +EP +E R +G ++++ F RYL S D + ++ DM QPL+HY+I+SSHNTYLT Q G SS E Y + L+ GCRC+ELDCWDG D EP+I HG + + ILF+DVI +I AF S P+ILS ENHC+ QQ +A++ +LG+ L+T P+
Sbjct: 183 FDESDSSHTGDLVEDEFVQLFRKLTRRDDVATLFKRLSPDGIGLPAARLAQFLQDEQHED---------DSEHRAACIIAEHEPLDEGRSKGLMTLDGFVRYLTSPDGSLWDQRHDSVSHDMTQPLSHYFISSSHNTYLTDDQLRGPSSTEAYVKSLMRGCRCVELDCWDGA--DGEPVIYHGYTLTSQILFRDVITSIAHEAFKASAYPVILSLENHCNVEQQIVMARHLRSILGERLVTAPL 415 HSP 2 Score: 176.407 bits (446), Expect = 1.381e-45 Identity = 109/269 (40.52%), Postives = 145/269 (53.90%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKK-------VGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGV--YEDTGK--LIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQT 2687
LS V Y V F+G + AE M SF+E +GLI A V YN + LSR YP G RV S N+ P WNAGCQ+VALNFQTP M L G F NG GY+LKP F+R P FDP + + G L I +ISGQ L ++ + V V+++G+ DT +E T NNGLNP++ ++ FLF ++ +P+LA++R V Y+ T + IGQ LP L+ GYRH+ L + L T+F I T
Sbjct: 491 LSDCVIYCSGVHFEGLERAESHQKGNEMCSFSETKTMGLIETQGNAFVRYNMQHLSRTYPSGTRVGSGNYNPHDMWNAGCQIVALNFQTPGKEMDLYDGLFRQNGGCGYVLKPSFLRDPHTDFDPGNPARGTGRHPVKLAITVISGQQLPKERNSRRGSIIDPLVSVEVHGVRGDTAVRE--THHQENNGLNPVWKEE--FLF-QLTVPELALIRFVVKDYDVTSRNDFIGQFSLPFSCLRQGYRHVHLLSLDGRSLFPATLFVHIRIT 754
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003983.1 (pep scaffold:Pmarinus_7.0:GL481506:4806:23311:-1 gene:ENSPMAG00000003626.1 transcript:ENSPMAT00000003983.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 172.94 bits (437), Expect = 3.140e-46 Identity = 85/161 (52.80%), Postives = 110/161 (68.32%), Query Frame = 3
Query: 963 EPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQD-MDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTK 1442
EPSE R+ G +S E F R+L+ DN L+ + + +PL+HYYI SSHNTYLTG Q G SSVE+YR VLL GCR +ELDCWD G+D PII HG + T I F+DV+ AI +AFVTSE+P+ILS ENHC QQ K+A+ ++V G+ L+T+
Sbjct: 3 EPSESMRQRGIMSFEGFARFLLDADNFACVLEESPPDESQLQRPLSHYYIASSHNTYLTGHQLKGDSSVELYRTVLLQGCRSVELDCWD--GDDGSPIIYHGHTLTTKIPFQDVVEAINRSAFVTSELPVILSIENHCCLAQQRKMAEIFKNVFGERLVTR 161 HSP 2 Score: 119.398 bits (298), Expect = 2.467e-28 Identity = 77/216 (35.65%), Postives = 110/216 (50.93%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIH--YHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVG--TYVEVDMYGLPTDTFRK-EFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGV 2546
+S +V Y Q VKF ++ + YHMSS NEN L RR + + QL R YP R++S+N P ++W G QMVALN+QT DL M LN FE NG G++LKP +RR + A + ++ISGQ++ +VE+++ G+P DT RT+ V N LNP++G+ V L +A LR+ V
Sbjct: 267 MSDLVIYCQAVKFPAKSLSALIRTPKCYHMSSMNENAAKRLCRRYGAKVPQHTMCQLLRTYPAATRIESSNPHPMLYWLHGIQMVALNYQTEDLPMALNAAMFEQNGGCGFVLKPPVLRRVRKRLRSACAR-AVVARRARADAQVISGQYVCPGNTAGSPHVELELAGMPLDTCHAGHLRTKTVARNALNPLWGETFTL---PVHLEAMAFLRLSV 478
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Yeast
Match: PLC1 (Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation [Source:SGD;Acc:S000006189]) HSP 1 Score: 102.834 bits (255), Expect = 1.751e-22 Identity = 52/116 (44.83%), Postives = 71/116 (61.21%), Query Frame = 3
Query: 1086 QPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLL 1433
+PL HY+I SSHNTYL G+Q SVE Y QVL GCRC+E+D WDG + P++ HG + + I K VI I+ AF+TS P+I+S E +C+K Q + +VL + L
Sbjct: 384 KPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDG---ENGPVVCHG-FLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQL 495 HSP 2 Score: 87.8113 bits (216), Expect = 6.700e-18 Identity = 84/283 (29.68%), Postives = 124/283 (43.82%), Query Frame = 3
Query: 1944 VKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCI--ALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEY-------NGNSGYLLKPEFMR---RPERSFDPFSESPMDGVIAATLEIKIISGQFL--------SDKKVGTYVEVDMY-----GLP------TDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISL-RTEGNFPLSLPTIFCKITQTTYI 2696
+KF+ F + E I H S NE +I+ + +L +N+R L R+YP R S+NF P FW AG QMVA N+QT D+ QLN F+ + SGY+LKP+ + + E +G T++I+I+S Q L S ++V+V+ + +P T E T+ NG NPI+ + + DL ++ V + + I L L L+ GYRHI L EG IFC + T I
Sbjct: 596 IKFRNFSLPESKTIA-HCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDT---DLTFIKFMVISEETQ-IASVCLKLNYLRMGYRHIPLFNMEGE-----QYIFCTLFIHTQI 868
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Nematostella
Match: EDO42237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S279]) HSP 1 Score: 858.21 bits (2216), Expect = 0.000e+0 Identity = 490/1165 (42.06%), Postives = 706/1165 (60.60%), Query Frame = 3
Query: 171 WRQPVSDDLINGAHFDRYDEDS-------NSLESNCLVRVDEYGFFVHWKSEQG-EGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKD-FITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFL-----KGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFI 3623
W V L +G R+DE S N L N VD+ GFF+ W+S+ EG +++S +S+VR G PK+ K+ L ++PL++R T+ T+LV+ +Y H+ + + +A W+ LRPL HN +++N + QL K +++ L A G I V+SI K +GK E ++ +L+ LGLP K+D+I P FTFE FY+LY K+CPR +I E+ E + +T +++ ++N+ QRDPRLNEILFPF + + ++ E + + ++ + RYL+S+DN + RLN+ DM+QPL+HY+INSSHNTYL GRQFGG+SSVE+YRQ L++GCRCIELDCWD G++ EPIITHG AMCT ILFKDVI AIRD+AF TS+ P+ILSFENHCSK QQYK+A YC D+LGD+L+TKP++ L + PLPSP +LR KILIKNK+LKPE E + F T+ + ++ E+ D ++ G K D H+ +N KV + SLT ++ ++A + T NI+P LS++VNY QPV FQGFD +E N+ Y MSSFNE+ G GL+R + V YNKRQ+SRIYPRG+RVDS+N+MPQ+FWN GCQMV+LNFQTPDL LNQGKFE+NG SGY+LKP+ MRR +R FDPF+ESP+DG + A + IK+ISGQ+LSDKK+ T VEVDMYGLPTDT RK+++T+ +NGLN +Y D +FR+VVLP++A+LR V +D ++I QRV+PL+ +Q+GYRH+ LRTE + P+ L T+F IT Y+PEG +VD L++P + +KR Q+ GI+ + V +P K+ S L P + + V P+ +F ISL L+ DKT++K+IKRQ +E E ++KK+ K+ ++ ++ T +KL ++ EI K + + R +K+LK +++ + + Q+ + ++ T TDEWTSM + EE + E++ +L + + E Q KE I ERE E+K +QTK SI+A K++ D+ +KNK ER+R++++L+ N K+F+
Sbjct: 8 WEVYVPLKLQSGTLLSRWDEASFLNKEPNNKLRINT-TYVDKCGFFLAWRSQDDKEGSSIEISNISEVRLGVLPKDQKVRESLQRTGADPLEERGFTVVYNTNLVDCNYLHLFASTSRVAKEWVEGLRPLLHNVRLDNCSVLTQLHKQYVKAGLHKDALGKISVKSICKALYAGKFESLVLDALQALGLPCSKNDKITPEDFTFEHFYQLYLKVCPRLEIMELCVEWGGGRAPILTATQLVNFMNKEQRDPRLNEILFPFCDNEKALSLIWKYEKQMDMLQRDRICVNGLTRYLLSEDNLLIMPGRLNLSDDMNQPLSHYFINSSHNTYLVGRQFGGRSSVEMYRQCLIAGCRCIELDCWD--GQNDEPIITHGNAMCTKILFKDVIEAIRDSAFQTSDFPVILSFENHCSKHQQYKMACYCMDILGDMLVTKPLESCPLEEGRPLPSPNQLRGKILIKNKKLKPEQEAEGESSFYGTKESSASTQSTESNGDDDEERDSVLPFKG--------------KRDDKGFGSTHRLNMNAYKKVSQ--------------------CCLDAASLTPDDVADIMASFPTQSTTGNINPLLSSLVNYIQPVPFQGFDESEKRNLFYQMSSFNESTGFGLVRATPLDFVKYNKRQMSRIYPRGSRVDSSNYMPQVFWNVGCQMVSLNFQTPDLPFHLNQGKFEFNGRSGYILKPDLMRRDDRMFDPFTESPIDGYVGAYVAIKVISGQYLSDKKITTVVEVDMYGLPTDTIRKKYKTKSSTSNGLNTLY-DGEHMVFRRVVLPEMALLRFAVIDDNDRIIAQRVVPLDSIQAGYRHVPLRTENDTPIPLATLFVHITLRCYVPEGYGAIVDELAEPIKFQCAADKRAAQMVVFGIDENVRARVIQV-EPRLLQHSKEHSRSVGFSLKPTINEQLFIGKYKIV--PI---------------EFIPISLEELKKDKTYRKVIKRQQKESEVIQKKYSKERVMMQRAHTSELEKLITSYD-EI--KQAAQKTYERATKRCGDDRAKALKAVYDKKIAYLSQSQREKAQKVLATQTDEWTSMISRQIAEEIAIYEQHAETQICVLQAALDQAHEIQLKETVIKHERENSEIKKRQTKQSIEAGKSIFMDKTIKNKEERERKLKQLDRHNLKQFV 1113
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Nematostella
Match: EDO43813 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXP6]) HSP 1 Score: 743.421 bits (1918), Expect = 0.000e+0 Identity = 375/796 (47.11%), Postives = 515/796 (64.70%), Query Frame = 3
Query: 411 NPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTE--KIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADM 2789
+PL ++ +TI G ++V++ Y VS + +A W ++L +THN N CP LKK + ++C+ +G + V+++ K +S E K I +L+ +GLP GK+D I F+F+ F+E Y+++C R DI++IF E+ + K ++ TE++++++N QRDPRLNEIL+P+ N++ + I+ EP++++ K+G S++ RYLMS+DNAP+ DRL++ QDM QP++HY+INSSHNTYLTG Q GKSSVE+YRQ LL+GCRCIELDCWDGK EDQEP+ITHG +CT+I FKDVI AI + AF TS+ P+ILSFENHC+ QQ K+A YC ++ GD+LL+KP+D + L + R P ++ ++ +K + I E N ++ + N PT P E E+NG E +PD AS++ S EE +A LS +VNY QPV F+ FD++ N Y MSSF E V ++ + V+YNKRQLSRIYP+G RV S N+MPQIFWNAGCQ+VALNFQT DLAM LN G FEYNG GY+LKP FMRR +R+FDPF+ES +DG+IA + +K+ISGQ L++KKVGTYVEV+MYGLP DT RK++RT+VVPNNG+NP+Y DD F F+KVVLP LAVLRI VYE++GKLIGQR+LP++GL GYRHI LR + N PL+LP +F I Y+P G D +AL DP A+ S+E+KR +QLA +
Sbjct: 18 DPLTEKAITIVHGANMVDLMYVTFVSSSSTMARQWTDSLVKITHNLLEINECPTTFLKKQYTKICVQTTQDGKVSVKNVIKYISSSSKEDRKRIQDALQSVGLPHGKNDAISLEKFSFDIFWEFYNRLCNRQDIDKIFTEIGTKKKPYMVTEQLVDFINNNQRDPRLNEILYPYCNEEKAREIIRKYEPNQDFVKKGHFSVQGLTRYLMSEDNAPIHPDRLSLHQDMTQPISHYFINSSHNTYLTGHQLTGKSSVEMYRQTLLAGCRCIELDCWDGKTEDQEPVITHGMTLCTEISFKDVIEAIAECAFKTSDYPVILSFENHCTPKQQLKMASYCVNIFGDMLLSKPLDDYPLEEG------------------RPLPPLKVLMRKIVIKNKKPIDSEPNATSD----------QAFSNNSAPPT--------PATEDKPPEING------------------EVDPD----ASQRDSTVEEEAAPDMA--------------LSELVNYFQPVHFKSFDVSAKRNRSYEMSSFVETVATTQLKEKPVEFVNYNKRQLSRIYPKGTRVGSENYMPQIFWNAGCQLVALNFQTLDLAMMLNLGIFEYNGRCGYILKPSFMRRSDRTFDPFAESTVDGIIAGAVHVKVISGQLLTEKKVGTYVEVEMYGLPADTVRKKYRTKVVPNNGINPVYDDDP-FEFKKVVLPSLAVLRIAVYEESGKLIGQRILPVDGLNPGYRHIKLRNDCNLPLTLPVLFVHIITKDYVPSGFEDFANALCDPIAFQSQEDKRQQQLAAL 740
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Nematostella
Match: EDO38229 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDH9]) HSP 1 Score: 202.601 bits (514), Expect = 1.562e-54 Identity = 116/302 (38.41%), Postives = 172/302 (56.95%), Query Frame = 3
Query: 1833 GSLTAEEEQAMLAQYHYIGA---------TTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKK--------VGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVY-EDTGK--LIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKI 2678
G+++ E+E A + Q A + LS VNY V F+ F+ +++ Y MSSF E+ L + V+YN RQLSR YP G+RVDS+N+ PQ+ WN GCQ+VALN+QT M LNQG+F N +GY+LKP +MR P+ F+P + GV L I++ISGQ L + + YVEV +YG+ +D+ +F+T+V+ +NG NP++ ++ + + + +P+LA+LR VY ED GK IGQ LP+ L++GYRHI L PL ++F +
Sbjct: 367 GTVSDEDEAADIEQEDLAAAREGEESKEKKVKLAKELSRCVNYISSVGFKNFEHSKENAKFYQMSSFVESKVATLAQNKAAGFVEYNTRQLSRTYPAGSRVDSSNYNPQVAWNVGCQIVALNYQTDGEYMHLNQGRFRENKRAGYVLKPAYMRNPDIKFNPNNPKSCPGVKKKLLIIQVISGQQLPKPQGSSSKGEVIDPYVEVKIYGVNSDS--ADFKTKVIKDNGFNPVWNEE---IKKLLYVPELAMLRFCVYDEDVGKDDFIGQFSLPITSLRTGYRHIHLLDIKGEPLPHASLFVHV 663 HSP 2 Score: 167.162 bits (422), Expect = 9.258e-43 Identity = 88/236 (37.29%), Postives = 133/236 (56.36%), Query Frame = 3
Query: 744 SSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPID 1451
++ E+F E + I R +I EI + ++ K + E + ++L + + E+ +K I+ EP+EE +++ +L I+ YL+S + + QDM QPL+HY+I SSHNTYL Q G SSV+ Y GCRC+ELDCWDG D PI+ HG + + I FKD+I A+ + AF S+ P+ILS ENHC+ Q K+A++ E++LGD L P+D
Sbjct: 106 AALNKEEFAEFFKAIATRDEIVEIMNKFTSGKAHMNVEDLQKFLYK----QGVKEV-----SKQYCDIIISTYEPTEEGQRDKQLGIDGLTNYLLSKEGDIFDTAHDKVYQDMRQPLSHYFIASSHNTYLMEDQLKGPSSVDAYINAFNKGCRCVELDCWDGDNGD--PIVYHGHTLTSKIKFKDIIQAVAEHAFKVSDYPVILSLENHCNIENQRKIAEHLENILGDKLFKDPVD 330
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Nematostella
Match: EDO46562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPT6]) HSP 1 Score: 197.208 bits (500), Expect = 1.202e-51 Identity = 107/280 (38.21%), Postives = 158/280 (56.43%), Query Frame = 3
Query: 1893 TTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKK----------VGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYED--TGK-LIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTY 2693
T + +LS +V YTQ F+G ++ ED H+ + S E Y + +L RIYP G R+DS+N PQ FWN GCQ+VALN+QT +Q+N+GKF NGN GY+LKP+ + + +SFDP + + GV L+I++ISGQ L K + YVEV++ G+P DT ++RT+ V +NG NP++ + VFL PD+A++R V+++ G+ IGQ LP + + G+RH+ L EG L T+FC +T Y
Sbjct: 600 TIRLSRHLSDLVAYTQSRAFKGLEVEEDGENHWEVISIPEPRAYRFTDTKATQFTRYTRYKLCRIYPAGYRIDSSNPNPQTFWNCGCQLVALNYQTEGRMLQINRGKFRANGNCGYVLKPDILCKESQSFDPMTRKDIPGVSKKVLKIRVISGQQLPKPKDSILGDRGEIIDPYVEVEIIGIPADT--SKYRTKTVIDNGFNPVWEETMVFLLN---FPDIALVRFVVWDEDPIGRDFIGQMTLPFQSIMPGFRHVHL--EG---LDQATVFCHVTIMDY 869 HSP 2 Score: 176.022 bits (445), Expect = 7.758e-45 Identity = 118/389 (30.33%), Postives = 194/389 (49.87%), Query Frame = 3
Query: 288 VHWK-SEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPL-THNTKMNNVCPMIQLKKHWLR---LCLGVKANGMIPVRSISKTFASGKTE-KIIFQSLKELGLPFGKSDEIDPSSFT-FEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLL 1433
+ W S++G+ + ++ V ++R G+ C+ + ++R T+ G + +V+ + E A W+ LR L + N + + WLR +G++ + + F K KI + ++E +D ++ S FE+F Y I R ++ + + NSK+ +T ++++ +L QR +E + I+ EP++ +K L I+ F YL+S D + ++ QDM +PL+HY+I SSHNTYLTG Q SS+++Y +VL SGCRC+ELDCWDGK D EP++ HG M + + F+ VI I D AF+ + P+ILS ENHCS QQ +A + D D+L
Sbjct: 49 ISWTPSKKGDRAKIPVNTVKEIREGTVSDAFSQCSEVFP------EERCFTLIHGESFATLD---LVAANREEAMHWMIGLRYLMAQHYGENEPTRRQKARDLWLRGIYTAADKSGDGLLSIDEVY--FLMHKLNVKISNRQVRE-NFKAADTDTVNSSGLLDFEEFANFYKSISTRRELYMLLLKYGNSKENMTVQELLNFLRIEQRVTECDE--------EYCSNIIQTYEPADSNKKNMLLGIDGFTSYLLSADGEIFNPEHSDVYQDMTRPLSHYFIASSHNTYLTGDQLASASSMDMYVRVLQSGCRCLELDCWDGK--DGEPVVYHGYTMTSKVKFRYVILNINDFAFLNNRYPVILSLENHCSVEQQKFMANFMRDTFKDIL 415
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Nematostella
Match: EDO46546 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ0]) HSP 1 Score: 192.2 bits (487), Expect = 8.535e-50 Identity = 117/316 (37.03%), Postives = 170/316 (53.80%), Query Frame = 3
Query: 1779 IKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGA----TTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGT--------YVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYED---TGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKIT 2681
I +K +K P S N + G ++ EE++ + H TT + LS +V+ + V FQ F + D + + S NE + L V+YNKR LSRIYP G RV S+N+ PQ WN GCQ+VALN+QTP + M +N GKF NG GY+LKP MR F+P ++ + G+ ++IK+ISGQ K T YV ++++G+P+D ++ RTR VP+NG NP++ D F F + LP++A+ R V +D IGQ +PL +Q G RH+ L PL T+F +T
Sbjct: 444 ILIKNKKLPASIDNDEEAGEVS-EEDEYVEENGHDANKNPRKTTKLARELSDLVSLCKSVTFQDFQYSADNQKFWELCSLNEALARRLGNAYPEEFVNYNKRCLSRIYPSGKRVGSSNYNPQDMWNCGCQLVALNYQTPGIMMHVNSGKFLENGECGYVLKPSVMRDEIAYFNPNTKDAIPGISPQIVQIKVISGQQFPKPKGSTAKGDVIDPYVTIEVFGIPSDIAQE--RTRTVPHNGFNPVF--DETFEFH-INLPEIALFRFVVQDDDFIGDGFIGQYTIPLNCMQQGDRHLRLLAFDGDPLDSATLFVHVT 753 HSP 2 Score: 177.178 bits (448), Expect = 4.932e-45 Identity = 133/416 (31.97%), Postives = 206/416 (49.52%), Query Frame = 3
Query: 234 SNSLESNCLVRVDEYGFFVHWK--SEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLD-DRIVTICSGTDLV--NISYTHMVSQDNEIATFWINNLRPLTHNTK-------MNNVCPMIQLKKHWLRLCLGVKAN-GMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTK 1442
SNS + +DE + WK S++ E + + V ++R G + I +D D I C+ + + N ++V+ + A W+ LR L + K ++++ LK+ ++ +G K I V ++ + E I+ Q K + S +S + E+F Y ++ R +I + +++ D++TT+ ++ +L Q R A K I+ EP+EE RK+ L I+ F +YLM D D+ NICQDM QPL+HY+I SSHNTYL Q G+SS+E Y L GCRC+ELDCWDG + EPII HG + + I+FK+ + AI + AF S P+ILS ENHC QQ +AKY +++L D L T+
Sbjct: 35 SNSRQYQRFFAIDEDFSTLRWKPSSKKPEKAKISMDTVREIRSGKNTE-----------IFREMDRDDIQEDCAFSIIYGDNFDTLNLVAYSPDEANIWVTGLRCLVDSEKDPLQLITIDSLTLHTWLKEQFVLADMGGKGRLNEIEVLTVLRQLKVQIPEVIVKQRFKATAV----SSAPQKNSLSREEFLSFYKELTTRPEIYFLLARYASNNDYLTTDDLLLFLESEQGITR--------AGKHYCLEIISRCEPTEEGRKKKCLGIDGFTQYLMESDCDIFDPDQQNICQDMTQPLSHYFIASSHNTYLLDNQLSGRSSIEGYIAALQQGCRCVELDCWDGPYD--EPIIYHGHTLTSKIMFKETVEAIEEHAFDVSPYPVILSIENHCCVKQQQIMAKYLKEILKDKLYTE 425
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Medaka
Match: PLCB4 (phospholipase C beta 4 [Source:NCBI gene;Acc:100049535]) HSP 1 Score: 1221.07 bits (3158), Expect = 0.000e+0 Identity = 644/1215 (53.00%), Postives = 855/1215 (70.37%), Query Frame = 3
Query: 150 SKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVL--LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSK-DFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLK----GQTE----IIQEENE-------------NAEDPDPLV-MVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLN-----IKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEV---QKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQ 3695
+K +EFNW++ + + + GA FDR+DED E NCLVRVDE+GFF+ WK+E EGQVL+ S ++ +R G+ PK+ KI + + + L+ I+ ICSG DLVN+S+ MV+ + E A WI LR + HN K NNVCPM LKKHW+++C NG IPVR I++TFASGKTEK IFQ+LK+LGLP GK+DEI+PS FTF+ FY L KICPRTDIEE+FK+++ +K D++T + ++ +LNE QRDPRLNEILFPF + I++ E EE +K+G++S + F RYLMSD+NAPVFLDRL + Q+MDQPLAHY+I+SSHNTYLTGRQFGGKSSVE+YRQVLLSGCRC+ELDCWDGKGEDQEPIITHGKAMCTDILFKDVI AI++TAFVTS+ P+ILSFENHCSKPQQYK+AKYCE++ GDLLL +P++ H + PLPSP L++KILIKNKRLKPEVE++Q E F K G+T I+ EE++ N+E P L M ++ + T+ +K + + N + KV E T+++ + E + D++K G + + E+A++AQY Y GATTNIHP+LSAMVNY QPVKFQ FD+AE+ NIHY+MSSFNE+VGLG ++ + I V+YNKRQ+SRIYP+G RVDS+N+MPQIFWNAGCQMV+LNFQTPDLAMQLNQGKFEYNG+ GYLLKP+FMRR +R FDPFSE+P+DGVIAAT +++ SGQFLSDKK+GTYVEVDMYGLPTDT RKEFRTR+V NNGLNP Y ++ F+FRKV+LPDLAVLRI VY+D KLIGQR+LPL+GLQ+GYRHISLR EGN PLSLPT+FC+I TY+P+G +VDALSDP+ +L+ EKR Q+ +GI+T+DI DVP +G K ++ + +TP ++ Q++NS NN + KKD N S+ L+ K + KL+K+Q +EL L+KKH K+ + K+ DK+ + H +E + K+ +K NC +E + E D I+ + K ++ ++ HT EW+ + H +E ++ + + E+L K++ QE Q +LK+I ER+ KEM+A Q K S++ +K + D+ +KNKAER+RR+RELN NTK+F+D+RK A K ++ ++L + EQ
Sbjct: 2 TKCYEFNWQKHLPEFMQEGASFDRFDEDPYLFEPNCLVRVDEFGFFITWKNEGKEGQVLECSLINSIRVGAVPKDPKILSSFESIGKTEADLEGCIICICSGADLVNLSFMFMVADNPETARKWIEGLRSVIHNFKANNVCPMTCLKKHWMKMCFLTNINGKIPVRGITRTFASGKTEKGIFQALKDLGLPSGKNDEIEPSDFTFDMFYALTQKICPRTDIEELFKKINGNKTDYLTVDHLVSFLNENQRDPRLNEILFPFYDPKRAMQIIEKYERDEELKKKGRMSSDGFCRYLMSDENAPVFLDRLELYQEMDQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSDYPVILSFENHCSKPQQYKMAKYCEEIFGDLLLKQPLESHPIEPGRPLPSPNDLKRKILIKNKRLKPEVEQKQFEAFKKHMEAGETNTPAIIMGEEDDVENGEKEGEEKDLNSEAPSCLSEMTSVKEANDVSLKETVSLKKEE---------QSNSIKKVPEHDGTEMSEATDATDISEASDQDNKK----AGEVAEDSEEALIAQYTYEGATTNIHPFLSAMVNYAQPVKFQSFDVAEERNIHYNMSSFNESVGLGYLKTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRSDRMFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPAYNEEP-FVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCQIILKTYVPDGFGAIVDALSDPKKFLTIAEKRADQMKALGIDTNDIADVP-SGNSKNDKKGKGKGDTVKTSVTPQASSDMAQTSNSA--------QNNTSESKKDATLVPNASIEDLKQTKAYLKLMKKQQKELNALKKKHSKEQNTMQKAHCTQVDKMVSLHEKEKSTLEKLLEKAFKKRGENNC------QELKKETEDKIQTLVTEHKAKVKEITAQHTKEWSELISGHSNKEQEMKDGHVMQQCEVLKKLLNNNQEQQTSQLKLIHERQSKEMRANQAKVSMENSKAINQDKTIKNKAERERRVRELNSSNTKKFLDERKRLAMKHQKEMEQLEKNQREQ 1187
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Medaka
Match: PLCB1 (phospholipase C beta 1 [Source:NCBI gene;Acc:101172698]) HSP 1 Score: 360.147 bits (923), Expect = 5.585e-104 Identity = 183/428 (42.76%), Postives = 266/428 (62.15%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIV----------DVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR 3167
+S +V Y QPVKF F+ ++ +N Y MSSF E L + + + V+YNK QLSRIYP+G RVDS+N+ PQ+FWNAGCQ+VALNFQT DL+MQLN G FEYNG GY LKPEFMRRP++ FDPF+ES +DG++A TL +KI+SGQFLSDKKVGTYVE+DM+GLP DT RK F+T+ N +NP++ ++++ +F+KVVLP LA LRI V+E+ GK IG R+ P ++ GY +I+LR E N L+LP++F + Y+P+ D+++ALS+P Y++ E+R QLA + +E D PT K + + +EN + P+ P+ S S + + E + ++ L+ K+F + ++Q +E++ L +KH + + + K T +L H R
Sbjct: 569 MSNLVLYIQPVKFHSFETSKKINRSYQMSSFVETKALEQLTKCPVEFVEYNKLQLSRIYPKGTRVDSSNYNPQLFWNAGCQLVALNFQTVDLSMQLNLGMFEYNGKCGYRLKPEFMRRPDKHFDPFTESTVDGIVANTLSVKILSGQFLSDKKVGTYVEIDMFGLPVDTKRKAFKTKTSQGNAINPVWEEEAI-VFKKVVLPTLASLRIAVFEEGGKFIGHRIFPASAIRPGYHYINLRNEKNQLLTLPSLFVYVEVKDYVPDTFADVIEALSNPIRYVNLMEQRANQLAALTLEEGGEEEGDKEVEAGSDAPTESK-VDRGVVQPAENGLETPIIPSKPPSLVGPTQSAGSLKPAAKTEDIIQSVLTE--LEAHTVEELKQQKSFVREQRKQYKEMKELVRKHHRKTGEMIKEHTARISELQGQHQR 992 HSP 2 Score: 349.747 bits (896), Expect = 2.391e-100 Identity = 179/437 (40.96%), Postives = 276/437 (63.16%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVR---FGSKPKEDKICAVL-LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKP-QQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
V + L G F ++++DS ++ L VD G+F++W + + +LD++ + D R F PK+ K+ VL + + L++R++T+ SGTD+VNI+Y + ++ EIA W L L N + N L+K + RL L + G IPV++I + F++ + K + +L+ LP G+++ I FT E + ICPR +++ IF E+ + S+ ++T E++ E++N QRDPRLNEIL+P + V+ ++D EP+ ++G++S+E F RYL ++N+ + ++L+ +DM PL+HY+INSSHNTYLT Q G SSVE+Y+QVLLSGCRCIELDCW G+ ++EP+ITHG M T+I FK+VI AI + AF TS PIILSFENH P QQ K+A+YC + GD LL +P++K++L V
Sbjct: 18 VPECLKKGNKFMKWEDDSTAVTPVTLT-VDPKGYFLYWTDQNKDTDLLDVAFIKDARNGKFCKMPKDAKLREVLDISTLVGKLENRMLTVVSGTDMVNITYLNFMAFQEEIAKEWAEELFKLASNLLVQNSSRETCLEKVYTRLKLQLNPEGRIPVKNIFRIFSADR--KRVETALESCNLPSGRNESIPQEDFTPEVYSMFLSNICPRPELDHIFSEIGAKSRPYLTVEQMTEFINSKQRDPRLNEILYPPLKAEQVQVLVDKYEPNASLAQKGQMSVEGFSRYLNGEENSIIPPEKLDQSEDMTFPLSHYFINSSHNTYLTAGQLAGNSSVEMYKQVLLSGCRCIELDCWKGRTTEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPIILSFENHVDSPKQQAKMAEYCRSIFGDALLMEPLEKYQLEAGV 451
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Medaka
Match: PLCB1 (phospholipase C beta 1 [Source:NCBI gene;Acc:101172698]) HSP 1 Score: 360.918 bits (925), Expect = 5.782e-104 Identity = 183/428 (42.76%), Postives = 266/428 (62.15%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIV----------DVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAR 3167
+S +V Y QPVKF F+ ++ +N Y MSSF E L + + + V+YNK QLSRIYP+G RVDS+N+ PQ+FWNAGCQ+VALNFQT DL+MQLN G FEYNG GY LKPEFMRRP++ FDPF+ES +DG++A TL +KI+SGQFLSDKKVGTYVE+DM+GLP DT RK F+T+ N +NP++ ++++ +F+KVVLP LA LRI V+E+ GK IG R+ P ++ GY +I+LR E N L+LP++F + Y+P+ D+++ALS+P Y++ E+R QLA + +E D PT K + + +EN + P+ P+ S S + + E + ++ L+ K+F + ++Q +E++ L +KH + + + K T +L H R
Sbjct: 569 MSNLVLYIQPVKFHSFETSKKINRSYQMSSFVETKALEQLTKCPVEFVEYNKLQLSRIYPKGTRVDSSNYNPQLFWNAGCQLVALNFQTVDLSMQLNLGMFEYNGKCGYRLKPEFMRRPDKHFDPFTESTVDGIVANTLSVKILSGQFLSDKKVGTYVEIDMFGLPVDTKRKAFKTKTSQGNAINPVWEEEAI-VFKKVVLPTLASLRIAVFEEGGKFIGHRIFPASAIRPGYHYINLRNEKNQLLTLPSLFVYVEVKDYVPDTFADVIEALSNPIRYVNLMEQRANQLAALTLEEGGEEEGDKEVEAGSDAPTESK-VDRGVVQPAENGLETPIIPSKPPSLVGPTQSAGSLKPAAKTEDIIQSVLTE--LEAHTVEELKQQKSFVREQRKQYKEMKELVRKHHRKTGEMIKEHTARISELQGQHQR 992 HSP 2 Score: 349.747 bits (896), Expect = 3.645e-100 Identity = 179/437 (40.96%), Postives = 276/437 (63.16%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVR---FGSKPKEDKICAVL-LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKP-QQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
V + L G F ++++DS ++ L VD G+F++W + + +LD++ + D R F PK+ K+ VL + + L++R++T+ SGTD+VNI+Y + ++ EIA W L L N + N L+K + RL L + G IPV++I + F++ + K + +L+ LP G+++ I FT E + ICPR +++ IF E+ + S+ ++T E++ E++N QRDPRLNEIL+P + V+ ++D EP+ ++G++S+E F RYL ++N+ + ++L+ +DM PL+HY+INSSHNTYLT Q G SSVE+Y+QVLLSGCRCIELDCW G+ ++EP+ITHG M T+I FK+VI AI + AF TS PIILSFENH P QQ K+A+YC + GD LL +P++K++L V
Sbjct: 18 VPECLKKGNKFMKWEDDSTAVTPVTLT-VDPKGYFLYWTDQNKDTDLLDVAFIKDARNGKFCKMPKDAKLREVLDISTLVGKLENRMLTVVSGTDMVNITYLNFMAFQEEIAKEWAEELFKLASNLLVQNSSRETCLEKVYTRLKLQLNPEGRIPVKNIFRIFSADR--KRVETALESCNLPSGRNESIPQEDFTPEVYSMFLSNICPRPELDHIFSEIGAKSRPYLTVEQMTEFINSKQRDPRLNEILYPPLKAEQVQVLVDKYEPNASLAQKGQMSVEGFSRYLNGEENSIIPPEKLDQSEDMTFPLSHYFINSSHNTYLTAGQLAGNSSVEMYKQVLLSGCRCIELDCWKGRTTEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPIILSFENHVDSPKQQAKMAEYCRSIFGDALLMEPLEKYQLEAGV 451
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Medaka
Match: PLCB1 (phospholipase C beta 1 [Source:NCBI gene;Acc:101172698]) HSP 1 Score: 352.443 bits (903), Expect = 3.088e-101 Identity = 158/294 (53.74%), Postives = 217/294 (73.81%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGI 2795
+S +V Y QPVKF F+ ++ +N Y MSSF E L + + + V+YNK QLSRIYP+G RVDS+N+ PQ+FWNAGCQ+VALNFQT DL+MQLN G FEYNG GY LKPEFMRRP++ FDPF+ES +DG++A TL +KI+SGQFLSDKKVGTYVE+DM+GLP DT RK F+T+ N +NP++ ++++ +F+KVVLP LA LRI V+E+ GK IG R+ P ++ GY +I+LR E N L+LP++F + Y+P+ D+++ALS+P Y++ E+R QLA + +
Sbjct: 563 MSNLVLYIQPVKFHSFETSKKINRSYQMSSFVETKALEQLTKCPVEFVEYNKLQLSRIYPKGTRVDSSNYNPQLFWNAGCQLVALNFQTVDLSMQLNLGMFEYNGKCGYRLKPEFMRRPDKHFDPFTESTVDGIVANTLSVKILSGQFLSDKKVGTYVEIDMFGLPVDTKRKAFKTKTSQGNAINPVWEEEAI-VFKKVVLPTLASLRIAVFEEGGKFIGHRIFPASAIRPGYHYINLRNEKNQLLTLPSLFVYVEVKDYVPDTFADVIEALSNPIRYVNLMEQRANQLAALTL 855 HSP 2 Score: 348.206 bits (892), Expect = 8.783e-100 Identity = 179/437 (40.96%), Postives = 276/437 (63.16%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVR---FGSKPKEDKICAVL-LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKEL-SNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKP-QQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
V + L G F ++++DS ++ L VD G+F++W + + +LD++ + D R F PK+ K+ VL + + L++R++T+ SGTD+VNI+Y + ++ EIA W L L N + N L+K + RL L + G IPV++I + F++ + K + +L+ LP G+++ I FT E + ICPR +++ IF E+ + S+ ++T E++ E++N QRDPRLNEIL+P + V+ ++D EP+ ++G++S+E F RYL ++N+ + ++L+ +DM PL+HY+INSSHNTYLT Q G SSVE+Y+QVLLSGCRCIELDCW G+ ++EP+ITHG M T+I FK+VI AI + AF TS PIILSFENH P QQ K+A+YC + GD LL +P++K++L V
Sbjct: 18 VPECLKKGNKFMKWEDDSTAVTPVTLT-VDPKGYFLYWTDQNKDTDLLDVAFIKDARNGKFCKMPKDAKLREVLDISTLVGKLENRMLTVVSGTDMVNITYLNFMAFQEEIAKEWAEELFKLASNLLVQNSSRETCLEKVYTRLKLQLNPEGRIPVKNIFRIFSADR--KRVETALESCNLPSGRNESIPQEDFTPEVYSMFLSNICPRPELDHIFSEIGAKSRPYLTVEQMTEFINSKQRDPRLNEILYPPLKAEQVQVLVDKYEPNASLAQKGQMSVEGFSRYLNGEENSIIPPEKLDQSEDMTFPLSHYFINSSHNTYLTAGQLAGNSSVEMYKQVLLSGCRCIELDCWKGRTTEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPIILSFENHVDSPKQQAKMAEYCRSIFGDALLMEPLEKYQLEAGV 451
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Medaka
Match: ENSORLT00000042446.1 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [Source:NCBI gene;Acc:101175365]) HSP 1 Score: 350.903 bits (899), Expect = 4.918e-101 Identity = 226/634 (35.65%), Postives = 349/634 (55.05%), Query Frame = 3
Query: 1914 LSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVP-NNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIE-------TSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVL-----------LETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKE 3758
+S +VNY QP KF F+ ++ YHMSSF E L + + + V+YNK QLSRIYP+G RVDS+NFMPQ+FWNAGCQ+VALN+QT DL+MQLN FEYNG SGY LKPEFMRRP++ FDPF+E+ +DG++A TL +K+ISGQFL++++VG YVEV+M+GLP DT RK +T+ NN +NP++ D+ +F+KV+LP LA LRI +E+ GK IG ++P+ ++ GYR+I LR E N L LP +F I Y+P+ D+++ALS+P Y++ E+R KQLA + +E T D D T + KP EN L+P + +T D K K +++ L + L+ K + K +RQ +EL+ L ++H+K ++ L RE N K K + R+ S E+E+ + +++++++Q L+ +++ S K + ++EH +++ E L + +E Q K+LK I ++E KE+K Q + + IN K K K + E+N + K + Q ++ +L +HD+ +E+ K + +E++F+E
Sbjct: 532 MSTLVNYVQPTKFNSFEASKKAARCYHMSSFVETKALEHLTKSPVEFVEYNKSQLSRIYPKGTRVDSSNFMPQLFWNAGCQLVALNYQTIDLSMQLNLFMFEYNGRSGYRLKPEFMRRPDKHFDPFTENTVDGIVANTLSVKVISGQFLTERRVGVYVEVEMFGLPADTRRKALKTKTSQNNNAINPVW-DEEPIVFKKVILPTLASLRIAAFEEGGKFIGHHIIPVSAIRPGYRYIGLRNERNQSLMLPAVFVYIEVKDYVPDTFADVIEALSNPIRYVNLLEQRSKQLAALTLEDGEEEAQTEDEADSTTEKRADLKP--ATVENG----LSPTSSQAGHTPAATTPKASSANQQAAAADPAKASVKTEDLVLSVLIEVPPCLLEHLQQSKLYSKEQRRQFKELKELSRRHQKKTSEL---------------LREFNNKYK---KMARQCS------KSRASSSESEKDERLQQLREDQHQQLLALRQEQFYSQK--YLQKEH------IKTLTERLSSLAEESHRGQMKKLKDICDKEKKELKRQMDRKRTEK----INQAKTKEKHLAEEEKIEINKSYVNEVVQNIKRLEETQAKRHDQLVEQHDQLLQEIQDQKLKLQAAVEVEFQE 1122 HSP 2 Score: 320.087 bits (819), Expect = 2.096e-90 Identity = 169/436 (38.76%), Postives = 266/436 (61.01%), Query Frame = 3
Query: 183 VSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPK---EDKICAVL-LERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHC-SKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAV 1475
VS L NG++F ++DED +++ + + VD GF+++W + + ++LDL+ V DVR G K E K+ +L + + L++R+VT+ + +DLVN++ + ++ + A W L L+ N +N+ L K ++RL L + +G IPV++I + F+S + K + +L LP+G+ D I FT E + +CPR ++ IFK + ++ +++ E++N QRDPRLNEIL+P +++ ++ + K G +S++ F YL SD+N + ++L+ +DM P++HY+INSSHNTYLT Q G SSVE+YRQVLL+GCRC+ELD W G+ ++EP+ITHG M ++I FK+VI AI + AF TS P+ILSFENH S QQ K+A+YC + GD LL P+DK+ L V
Sbjct: 18 VSHTLRNGSNFIKWDEDLSTV-TPVTLHVDPNGFYLYWTDQNKDTELLDLTVVKDVRTGRSTKTTKEAKLRELLDVGNLVGRLENRMVTVVTASDLVNVNQLNFIASQEDEAKVWCEELFSLSSNLLSHNLNRDQSLLKAYVRLTLQLNTDGRIPVKNIVRLFSSDR--KRVETALDSCRLPYGRGDSIRVEDFTLEVYKSFLDSLCPRPELGNIFKLQGGNGGMLSIDQMTEFINNKQRDPRLNEILYPPFRPAQTLSLMERHQLDQAELKRGLISLQAFSMYLSSDENGVIPPEKLDQSEDMSFPMSHYFINSSHNTYLTAGQLAGSSSVEMYRQVLLAGCRCVELDVWKGRTAEEEPVITHGFTMTSEISFKEVIEAIAECAFKTSLFPVILSFENHVDSLKQQAKMAEYCRSIFGDALLIDPLDKYPLEAGV 450
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Planmine SMEST
Match: SMESG000049234.1 (SMESG000049234.1) HSP 1 Score: 2384.76 bits (6179), Expect = 0.000e+0 Identity = 1206/1228 (98.21%), Postives = 1207/1228 (98.29%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGK+DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKG NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI
Sbjct: 1 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKNDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGE--------------------NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 1208
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Planmine SMEST
Match: SMESG000049234.1 (SMESG000049234.1) HSP 1 Score: 2379.75 bits (6166), Expect = 0.000e+0 Identity = 1227/1267 (96.84%), Postives = 1228/1267 (96.92%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE---------------------------------------DLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGK+DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE DLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYSKSLKEKENEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI
Sbjct: 1 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKNDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEEEAYHFHMSSFSETVALGYLKNEAIEFCFVLMHDYILLLDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYSKSLKEKENEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 1267
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Planmine SMEST
Match: SMESG000049234.1 (SMESG000049234.1) HSP 1 Score: 2337.76 bits (6057), Expect = 0.000e+0 Identity = 1206/1267 (95.19%), Postives = 1207/1267 (95.26%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE---------------------------------------DLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGK+DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE DLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKG NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI
Sbjct: 1 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKNDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEEEAYHFHMSSFSETVALGYLKNEAIEFCFVLMHDYILLLDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGE--------------------NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 1247
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Planmine SMEST
Match: SMESG000049234.1 (SMESG000049234.1) HSP 1 Score: 2331.98 bits (6042), Expect = 0.000e+0 Identity = 1206/1279 (94.29%), Postives = 1207/1279 (94.37%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE---------------------------------------------------DLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGK+DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE DLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKG NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI
Sbjct: 1 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKNDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEEEAYHFHMSSFSETVALGYLKNEAIEFVKYPKFLFFPLNCFVLMHDYILLLDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGE--------------------NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 1259
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Planmine SMEST
Match: SMESG000049234.1 (SMESG000049234.1) HSP 1 Score: 2326.21 bits (6027), Expect = 0.000e+0 Identity = 1189/1228 (96.82%), Postives = 1197/1228 (97.48%), Query Frame = 3
Query: 108 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKSDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVXXXXXXXXXXXXXXXXXXXXXEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEDLNIHYHMSSFNENVGLGLIRRDCIALVDYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNXXXXXXXEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGSLMRKISHYNCLYXXXXXXXXXXXXDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIXXXXXXXXXXXXXTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 3791
MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGK+DEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAE+ H+HMSSF+E V LG ++ + I V+YNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKG NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI
Sbjct: 1 MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCLVRVDEYGFFVHWKSEQGEGQVLDLSQVSDVRFGSKPKEDKICAVLLERISNPLDDRIVTICSGTDLVNISYTHMVSQDNEIATFWINNLRPLTHNTKMNNVCPMIQLKKHWLRLCLGVKANGMIPVRSISKTFASGKTEKIIFQSLKELGLPFGKNDEIDPSSFTFEKFYELYHKICPRTDIEEIFKELSNSKDFITTEKIIEYLNEVQRDPRLNEILFPFANKDTVKYILDNNEPSEEYRKEGKLSIECFYRYLMSDDNAPVFLDRLNICQDMDQPLAHYYINSSHNTYLTGRQFGGKSSVEIYRQVLLSGCRCIELDCWDGKGEDQEPIITHGKAMCTDILFKDVIYAIRDTAFVTSEMPIILSFENHCSKPQQYKLAKYCEDVLGDLLLTKPIDKHELSQAVPLPSPLKLRKKILIKNKRLKPEVEKQQLEMFLKGQTEIIQEENENAEDPDPLVMVDGEDGPMNEINPTIIVKNDTDPHPEMHKTELNGLLKVKEQSDTQLNIKVKEEKEPDSRKNASKKGSLTAEEEQAMLAQYHYIGATTNIHPYLSAMVNYTQPVKFQGFDIAEEEAYHFHMSSFSETVALGYLKNEAIEFVNYNKRQLSRIYPRGNRVDSANFMPQIFWNAGCQMVALNFQTPDLAMQLNQGKFEYNGNSGYLLKPEFMRRPERSFDPFSESPMDGVIAATLEIKIISGQFLSDKKVGTYVEVDMYGLPTDTFRKEFRTRVVPNNGLNPIYGDDSVFLFRKVVLPDLAVLRIGVYEDTGKLIGQRVLPLEGLQSGYRHISLRTEGNFPLSLPTIFCKITQTTYIPEGLVDLVDALSDPRAYLSKEEKRMKQLADMGIETSDIVDVPTTGKPFKKPPDKKSENSNQEPLTPNLANKSGQSNNSTVSTPVVGFSNNKKDDKKDEPKFDNISLVLLETDKTFQKLIKRQTRELENLRKKHEKDSAILHKSQTIVTDKLNANHAREINKKVKVKGE--------------------NEESDMIEEVQKNQMVDLVKTHTDEWTSMKLQHRKEEHDLCMSFLESRQELLLKVMKEVQEDQKKELKIIQEREIKEMKAQQTKASIDANKNVINDRKLKNKAERDRRIRELNDINTKRFIDQRKAQAQKQDRQTQELNRKHDEQEKEVVSAIDKERHLLEMKFKEDLLATKRATAI 1208 The following BLAST results are available for this feature:
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30011684 ID=SMED30011684|Name=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=4174bpback to top protein sequence of SMED30011684-orf-1 >SMED30011684-orf-1 ID=SMED30011684-orf-1|Name=SMED30011684-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1229bp MTSDIAKRQRTVPSSKAFEFNWRQPVSDDLINGAHFDRYDEDSNSLESNCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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