RRM domain-containing protein

Overview


Name	RRM domain-containing protein
Smed ID	SMED30011677
Length (bp)	1524

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of RRM domain-containing protein (SMED30011677) t-SNE clustered cells

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30011677) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RRM domain-containing protein (SMED30011677) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30011677) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30011677

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 23

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30011677	SMESG000018666.1	Contig3691	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30011677	SMESG000018666.1	Contig3691	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30011677	SMESG000070758.1	Contig3691	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30011677	SMESG000070758.1	Contig3691	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
X1 cell	SMED30011677	SMESG000018666.1	SmedASXL_015492	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30011677	SMESG000018666.1	SmedASXL_015492	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30011677	SMESG000018666.1	SmedASXL_015493	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30011677	SMESG000018666.1	SmedASXL_015493	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
neoblast	SMED30011677	SMESG000018666.1 SMESG000018665.1	dd_Smed_v4_10611_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30011677	SMESG000018666.1	CUFF.172807.1	be_Smed_v2	PMID:22543868 Onal et al., 2012
tail stripe	SMED30011677	SMESG000018666.1	CUFF.172807.1	be_Smed_v2	PMID:22543868 Onal et al., 2012
reproductive organ	SMED30011677	SMESG000018666.1	Contig32058	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30011677	SMESG000018666.1	Contig32058	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30011677	SMESG000018666.1 SMESG000018665.1	Contig38356	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30011677	SMESG000018666.1 SMESG000018665.1	Contig38356	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
ovary	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
testis	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
testis	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatogonium	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatocyte	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatid	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
spermatogonial stem cell	SMED30011677	SMESG000018666.1	KU519616	smed_ncbi_20200123	PMID:27330085 Iyer et al., 2016
testis primordium	SMED30011677	SMESG000018666.1	Contig6439_SE3	GPL10652	PMID:20844018 Wang et al., 2010

Note: Hover over icons to view figure legend

Homology

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BLAST of RRM domain-containing protein vs. Ensembl Human
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 119.783 bits (299), Expect = 7.571e-30
Identity = 58/91 (63.74%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 113

[Close]

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 119.783 bits (299), Expect = 8.960e-30
Identity = 58/91 (63.74%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   37 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 125

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 119.398 bits (298), Expect = 2.516e-29
Identity = 58/91 (63.74%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: DAZL (deleted in azoospermia like [Source:HGNC Symbol;Acc:HGNC:2685])

HSP 1 Score: 83.1889 bits (204), Expect = 1.042e-17
Identity = 42/90 (46.67%), Postives = 61/90 (67.78%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFL 557
            G ++PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++   + F  +KL +G A+RKQ   
Sbjct:   73 GKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFFNDVDVQKIVESQ---INFHGKKLKLGPAIRKQNLC 158

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: daz-1 (DAZ protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20870])

HSP 1 Score: 88.1965 bits (217), Expect = 2.083e-18
Identity = 48/108 (44.44%), Postives = 66/108 (61.11%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRK---QKFLEQFYIMDPCLML 593
            P    LIPNRIFVGG  ++TTE EL+  F  +  +KDVK++    G SKG YGF+TFE ++ AE+I K   + L F+ RKLN+G A+RK     F   + I  P  ++
Sbjct:   58 PPTYELIPNRIFVGGFPTSTTETELREHFEKFFAVKDVKMVKSLDGQSKG-YGFITFETEDQAEEIRKLTPKQLEFRSRKLNLGPAIRKINSNSFQPSYAIATPSQLV 164

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: sup-12 (SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189])

HSP 1 Score: 51.2174 bits (121), Expect = 1.574e-7
Identity = 26/77 (33.77%), Postives = 44/77 (57.14%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHA 536
            +IFVGG+  +T+++ L  +F  +G I++  +I DR       YGFVT +++ +AE+  K+     I   RK N+  A
Sbjct:   36 KIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKD--PNPIIDGRKANVNLA 110

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: msi-1 (MuSashI (Fly neural) family; Neural RNA-binding protein MSI-1 [Source:UniProtKB/TrEMBL;Acc:G5EFS2])

HSP 1 Score: 53.1434 bits (126), Expect = 2.166e-7
Identity = 19/59 (32.20%), Postives = 41/59 (69.49%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK 482
            ++F+GG+++ +T E++K +F +YG ++D  ++ D+       +GFVTF++ E A+K+ +
Sbjct:  135 KVFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDKATQRHRGFGFVTFDSDEVADKVCE 193

HSP 2 Score: 49.6766 bits (117), Expect = 2.961e-6
Identity = 23/90 (25.56%), Postives = 45/90 (50.00%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFL 557
            G+  P ++F+GG++  TT E L+ +F  +G + +  ++ D        +GF+TF +  + +K++ N    L  K+    +    R Q  L
Sbjct:   40 GSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPATKRARGFGFITFVDPSSVDKVLNNREHELDGKKIDPKVAFPKRTQAKL 129

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: sup-12 (SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189])

HSP 1 Score: 51.2174 bits (121), Expect = 5.329e-7
Identity = 25/74 (33.78%), Postives = 43/74 (58.11%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNI 527
            +IFVGG+  +T+++ L  +F  +G I++  +I DR       YGFVT +++ +AE+  K+     I   RK N+
Sbjct:   36 KIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACKD--PNPIIDGRKANV 107

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: H28G03.1 (pep chromosome:WBcel235:X:5216363:5219095:1 gene:WBGene00019249.1 transcript:H28G03.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:H28G03.1)

HSP 1 Score: 51.6026 bits (122), Expect = 5.916e-7
Identity = 22/65 (33.85%), Postives = 39/65 (60.00%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 500
            ++F+GG++ +TT+E+L  +FS +GP+ D  +I D        +GFVTF +  +AE  + +    L
Sbjct:   71 KLFIGGLSHDTTDEQLGNYFSQWGPVVDAIVIRDPNTKHSRGFGFVTFASIFSAESAMNDRPHKL 135

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076539)

HSP 1 Score: 105.145 bits (261), Expect = 7.065e-26
Identity = 50/91 (54.95%), Postives = 69/91 (75.82%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ 
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076541)

HSP 1 Score: 105.145 bits (261), Expect = 7.065e-26
Identity = 50/91 (54.95%), Postives = 69/91 (75.82%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ 
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076538)

HSP 1 Score: 105.531 bits (262), Expect = 1.142e-25
Identity = 50/91 (54.95%), Postives = 69/91 (75.82%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ 
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0344979)

HSP 1 Score: 105.531 bits (262), Expect = 1.142e-25
Identity = 50/91 (54.95%), Postives = 69/91 (75.82%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ 
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: bol (gene:FBgn0011206 transcript:FBtr0076540)

HSP 1 Score: 105.531 bits (262), Expect = 1.142e-25
Identity = 50/91 (54.95%), Postives = 69/91 (75.82%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ 
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP 113

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 68.1662 bits (165), Expect = 3.537e-13
Identity = 36/88 (40.91%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K++
Sbjct:   52 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 135

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 68.5514 bits (166), Expect = 6.195e-13
Identity = 36/88 (40.91%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K++
Sbjct:   25 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 108

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 68.5514 bits (166), Expect = 6.816e-13
Identity = 36/88 (40.91%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K++
Sbjct:   25 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIV----DPISFKGKKLKLGPAIMKER 107

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 68.5514 bits (166), Expect = 7.383e-13
Identity = 36/88 (40.91%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K++
Sbjct:   25 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 108

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:58039])

HSP 1 Score: 68.5514 bits (166), Expect = 9.514e-13
Identity = 36/88 (40.91%), Postives = 53/88 (60.23%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G + PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I+    + + FK +KL +G A+ K++
Sbjct:   42 GKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVD---QPISFKGKKLKLGPAIMKER 125

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: dazl (deleted in azoospermia-like [Source:NCBI gene;Acc:394676])

HSP 1 Score: 77.0258 bits (188), Expect = 4.230e-15
Identity = 40/88 (45.45%), Postives = 58/88 (65.91%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G +IPN +FVGGI     E  +   F  YG +KD+KII DRTG+SKG YGFV+F ++   +KI+K++   + F  +KL +G A+RK +
Sbjct:   25 GKVIPNTVFVGGIDITMDEMAIGNLFEKYGKVKDLKIITDRTGVSKG-YGFVSFYDEVDVQKIVKSQ---INFHGKKLKLGPAIRKMQ 108

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: deup1 (deuterosome assembly protein 1 [Source:Xenbase;Acc:XB-GENE-5961526])

HSP 1 Score: 57.7658 bits (138), Expect = 2.331e-8
Identity = 26/69 (37.68%), Postives = 43/69 (62.32%), Query Frame = 3

Query:  294 LIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 500
            L   +IFVGGI  +T E  L+ +F SYG I+ ++++ DR    K  + FVTF++ +T +KI+  +  T+
Sbjct:  115 LTVKKIFVGGIKEDTEEYHLRDYFQSYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTI 183

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: rbm24 (RNA binding motif protein 24 [Source:NCBI gene;Acc:394612])

HSP 1 Score: 56.225 bits (134), Expect = 2.524e-8
Identity = 28/87 (32.18%), Postives = 52/87 (59.77%), Query Frame = 3

Query:  303 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
             +IFVGG+  +TT+  L+ +F  +G I++  +I DR TG S+G YGFVT  ++  AE+  K+    +  ++  +N+ +   K + ++
Sbjct:   11 TKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRG-YGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQ 96

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: nxph2 (neurexophilin 2 [Source:Xenbase;Acc:XB-GENE-951506])

HSP 1 Score: 55.8398 bits (133), Expect = 2.920e-8
Identity = 29/87 (33.33%), Postives = 51/87 (58.62%), Query Frame = 3

Query:  303 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
             +IFVGG+  +TT+  L+ +F  +G I +  +I DR TG S+G YGFVT  ++  AE+  K+    +  ++  +N+ +   K + L+
Sbjct:   11 TKIFVGGLPYHTTDASLRKYFEVFGDIDEAVVITDRQTGKSRG-YGFVTMSDRAAAERACKDPNPIIDGRKANVNLAYLGAKPRNLQ 96

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: hnrnpa2b1 (heterogeneous nuclear ribonucleoprotein A2/B1 [Source:NCBI gene;Acc:549680])

HSP 1 Score: 55.4546 bits (132), Expect = 1.071e-7
Identity = 24/65 (36.92%), Postives = 41/65 (63.08%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 500
            ++FVGGI  +T E  L+ +F  YG I+ ++II D+    K  +GFVTF++ +  +KI+  +  T+
Sbjct:  101 KLFVGGIKEDTEEHHLREYFEEYGKIESIEIITDKQSGKKRGFGFVTFDDHDPVDKIVLQKYHTI 165

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Boll (boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638])

HSP 1 Score: 116.701 bits (291), Expect = 1.446e-30
Identity = 57/91 (62.64%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   37 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 125

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Boll (boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638])

HSP 1 Score: 118.242 bits (295), Expect = 1.532e-29
Identity = 57/91 (62.64%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   24 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 112

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Boll (boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638])

HSP 1 Score: 118.627 bits (296), Expect = 1.704e-29
Identity = 57/91 (62.64%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   37 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 125

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Dazl (deleted in azoospermia-like [Source:MGI Symbol;Acc:MGI:1342328])

HSP 1 Score: 85.1149 bits (209), Expect = 9.096e-18
Identity = 42/90 (46.67%), Postives = 61/90 (67.78%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFL 557
            G ++PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++   + F  +KL +G A+RKQ   
Sbjct:   35 GKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFYNDVDVQKIVESQ---INFHGKKLKLGPAIRKQNLC 120

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Dazl (deleted in azoospermia-like [Source:MGI Symbol;Acc:MGI:1342328])

HSP 1 Score: 82.0333 bits (201), Expect = 4.614e-17
Identity = 41/87 (47.13%), Postives = 59/87 (67.82%), Query Frame = 3

Query:  297 IPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFL 557
            +PN +FVGGI     E E++ FF+ YG +K+VKII DRTG+SKG YGFV+F N    +KI++++   + F  +KL +G A+RKQ   
Sbjct:    1 MPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG-YGFVSFYNDVDVQKIVESQ---INFHGKKLKLGPAIRKQNLC 83

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8WP23|BOLL_MACFA (Protein boule-like OS=Macaca fascicularis OX=9541 GN=BOLL PE=2 SV=2)

HSP 1 Score: 119.783 bits (299), Expect = 3.391e-29
Identity = 58/91 (63.74%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 113

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8N9W6|BOLL_HUMAN (Protein boule-like OS=Homo sapiens OX=9606 GN=BOLL PE=1 SV=2)

HSP 1 Score: 119.783 bits (299), Expect = 3.636e-29
Identity = 58/91 (63.74%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGFVTFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFVTFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 113

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q924M5|BOLL_MOUSE (Protein boule-like OS=Mus musculus OX=10090 GN=Boll PE=1 SV=2)

HSP 1 Score: 118.242 bits (295), Expect = 1.059e-28
Identity = 57/91 (62.64%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI   T E +L+ FFS YG +K+VKI+NDR G+SKG YGF+TFE QE A+KI++ EAE L +K++KLNIG A+RKQ+
Sbjct:   25 PRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKG-YGFITFETQEDAQKILQ-EAEKLNYKDKKLNIGPAIRKQQ 113

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q24207|BOULE_DROME (Protein boule OS=Drosophila melanogaster OX=7227 GN=bol PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 1.145e-24
Identity = 50/91 (54.95%), Postives = 69/91 (75.82%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            PK GTLIPNRIFVGGI+ +TTE +L   FS+YG +K  KII DR G+SKG YGFVTFE ++ A++ ++ + E ++ ++RKLNI  A++KQ 
Sbjct:   25 PKYGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKG-YGFVTFETEQEAQR-LQADGECVVLRDRKLNIAPAIKKQP 113

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q20870|DAZ1_CAEEL (DAZ protein 1 OS=Caenorhabditis elegans OX=6239 GN=daz-1 PE=2 SV=3)

HSP 1 Score: 88.1965 bits (217), Expect = 2.612e-17
Identity = 48/108 (44.44%), Postives = 66/108 (61.11%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRK---QKFLEQFYIMDPCLML 593
            P    LIPNRIFVGG  ++TTE EL+  F  +  +KDVK++    G SKG YGF+TFE ++ AE+I K   + L F+ RKLN+G A+RK     F   + I  P  ++
Sbjct:   59 PPTYELIPNRIFVGGFPTSTTETELREHFEKFFAVKDVKMVKSLDGQSKG-YGFITFETEDQAEEIRKLTPKQLEFRSRKLNLGPAIRKINSNSFQPSYAIATPSQLV 165

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A172RVQ0 (Boule 1 RNA-binding protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 266.544 bits (680), Expect = 3.503e-84
Identity = 144/149 (96.64%), Postives = 145/149 (97.32%), Query Frame = 3

Query:  159 ILFFKQSTDSQLTPKVDTLAQEFQVSLXXXXXXXXXXXXXPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQFYIMDPCLMLYKMV 605
            I    +STDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQFYIMDPCLMLYKMV
Sbjct:    6 ISMIHRSTDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQFYIMDPCLMLYKMV 154

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A3P6SII3 (RRM domain-containing protein (Fragment) OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS2692 PE=4 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 5.388e-42
Identity = 74/95 (77.89%), Postives = 86/95 (90.53%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQ 563
            PK GTLIPNRIFVGGI SNTTE+ELK +FSS+G +KDVKIINDR G++KGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ+   +
Sbjct:   14 PKFGTLIPNRIFVGGIPSNTTEQELKTYFSSFGQVKDVKIINDRLGVAKGSYGFVTFESQEMAEKIIKNESETLIFKDRKLNIGHAIRKQQLFPR 108

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A5K3F9R3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 6.169e-42
Identity = 78/112 (69.64%), Postives = 90/112 (80.36%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQFYIMDPCLMLYKMV*HC 614
            PK GTLIPNRIFVGGI SNTTE+ELK +FSS+G +KDVKIINDR G+SKGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ+   +   + P L        C
Sbjct:   38 PKFGTLIPNRIFVGGIPSNTTEQELKTYFSSFGQVKDVKIINDRLGVSKGSYGFVTFESQEVAEKIIKNESETLIFKDRKLNIGHAIRKQQLFPRPADVPPALFFAGGAIPC 149

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A564XYF3 (RRM domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS987 PE=4 SV=1)

HSP 1 Score: 164.466 bits (415), Expect = 7.136e-42
Identity = 77/103 (74.76%), Postives = 89/103 (86.41%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQFYIMDPCL 587
            PKIGTLIPNRIFVGGI SNTTE+ELK +FSS+G +KDVKIINDR G++KGSYGFVTFE QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ+   +   + P L
Sbjct:   38 PKIGTLIPNRIFVGGIPSNTTEQELKAYFSSFGQVKDVKIINDRLGVAKGSYGFVTFECQEVAEKIIKNESETLIFKDRKLNIGHAIRKQQLFPRPADVAPTL 140

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A5K4EPW2 (Boule-related OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 2.331e-41
Identity = 75/93 (80.65%), Postives = 83/93 (89.25%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFL 557
            PK GTLIPNRIFVGGI SNT E+ELK FFSS+G +KDVKIINDR G SKGSYGFVTFE+QE AEKIIKNE+ETLIFK+RKLNIGHA+RKQ+  
Sbjct:   36 PKFGTLIPNRIFVGGIPSNTNEQELKSFFSSFGHVKDVKIINDRLGASKGSYGFVTFESQEMAEKIIKNESETLIFKDRKLNIGHAIRKQQIF 128

HSP 2 Score: 38.5058 bits (88), Expect = 2.331e-41
Identity = 15/36 (41.67%), Postives = 27/36 (75.00%), Query Frame = 2

Query:  542 KTEISGTVLYNG-PVPYALQNGLTLFQVPGQDYSVL 646
            + E++ T+L+ G  +PY+ QNG+ +F +PGQ+Y +L
Sbjct:  130 RPELTTTLLFTGSAIPYSFQNGMAVFPLPGQEYPIL 165

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000005184.2 (pep primary_assembly:Astyanax_mexicanus-2.0:10:7750630:7761219:-1 gene:ENSAMXG00000005058.2 transcript:ENSAMXT00000005184.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.99 bits (258), Expect = 8.302e-25
Identity = 49/87 (56.32%), Postives = 67/87 (77.01%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 548
            GT+IPNRIFVGGI     E +L+ FFS YG I++V I+ DR G+SKG YGFVTFE QE A+KI+ ++A+ L F+++++N+G A RKQ
Sbjct:   32 GTVIPNRIFVGGIGGKAKENDLRCFFSEYGVIREVNIVTDRDGISKG-YGFVTFETQEDAQKIL-HDADRLSFRDKRINVGQAFRKQ 116

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: dazl (deleted in azoospermia like [Source:NCBI gene;Acc:103038434])

HSP 1 Score: 70.0922 bits (170), Expect = 2.201e-13
Identity = 37/88 (42.05%), Postives = 54/88 (61.36%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G L PN +FVGGI     E E++ FF+ YG +K+VKII  R G+ KG YGFV F      + I++ +   + FK +KL +G A+ K++
Sbjct:   26 GKLTPNTLFVGGIDMKVEENEIRDFFARYGAVKEVKIITYRGGICKG-YGFVYFSEDVDIQTIVEQQ---ISFKGKKLKLGPAIMKER 109

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000016054.2 (RNA binding motif protein 38 [Source:NCBI gene;Acc:103039930])

HSP 1 Score: 55.8398 bits (133), Expect = 1.815e-8
Identity = 29/86 (33.72%), Postives = 51/86 (59.30%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
            +IFVGG+  +T +  L+ +F +YG I +  +I DR TG S+G YGFVT  ++  AE+  K+    +  ++  +N+ +   K + L+
Sbjct:   27 KIFVGGLPYHTNDASLRKYFEAYGDIDEAVVITDRQTGKSRG-YGFVTMTDRVAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQ 111

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: rbm24a (RNA binding motif protein 24 [Source:NCBI gene;Acc:103027480])

HSP 1 Score: 54.6842 bits (130), Expect = 4.056e-8
Identity = 27/87 (31.03%), Postives = 52/87 (59.77%), Query Frame = 3

Query:  303 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
             +IFVGG+  +TT+  L+ +F  +G I++  +I DR TG S+G YGFVT  ++  A++  K+    +  ++  +N+ +   K + ++
Sbjct:   11 TKIFVGGLPYHTTDSSLRKYFEVFGEIEEAVVITDRQTGKSRG-YGFVTMADRSAADRACKDPNPIIDGRKANVNLAYLGAKPRVMQ 96

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: rbm24a (RNA binding motif protein 24 [Source:NCBI gene;Acc:103027480])

HSP 1 Score: 55.0694 bits (131), Expect = 4.749e-8
Identity = 27/87 (31.03%), Postives = 52/87 (59.77%), Query Frame = 3

Query:  303 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
             +IFVGG+  +TT+  L+ +F  +G I++  +I DR TG S+G YGFVT  ++  A++  K+    +  ++  +N+ +   K + ++
Sbjct:   32 TKIFVGGLPYHTTDSSLRKYFEVFGEIEEAVVITDRQTGKSRG-YGFVTMADRSAADRACKDPNPIIDGRKANVNLAYLGAKPRVMQ 117

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: BOLL (boule homolog, RNA binding protein [Source:HGNC Symbol;Acc:HGNC:14273])

HSP 1 Score: 118.242 bits (295), Expect = 3.416e-30
Identity = 57/91 (62.64%), Postives = 74/91 (81.32%), Query Frame = 3

Query:  279 PKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            P+ GT+IPNRIFVGGI     E ELK +F+ +G +KDVKIINDR G+SKG YGFVTFE+QE A+K I+ EAE +++K++KLNIG A+RKQ+
Sbjct:   34 PRYGTVIPNRIFVGGIDFKVNEAELKKYFTQFGVVKDVKIINDRAGVSKG-YGFVTFESQEDAQK-IQQEAEKIMYKDKKLNIGPAIRKQQ 122

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030])

HSP 1 Score: 60.077 bits (144), Expect = 4.728e-10
Identity = 25/65 (38.46%), Postives = 41/65 (63.08%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 500
            +IFVGGI  NT E+ L+ +FS YG ++ V ++ DR    K  +GFVTF + +  +K++  +  T+
Sbjct:  125 KIFVGGIKDNTDEDHLRDYFSEYGMVESVDVMEDRQSGKKRGFGFVTFSDHDAVDKVVVQKYHTI 189

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030])

HSP 1 Score: 57.3806 bits (137), Expect = 7.791e-10
Identity = 24/65 (36.92%), Postives = 42/65 (64.62%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETL 500
            +IFVGGI  +T E+ L+ +F  YG ++  +++ DR+   K  +GFVTF + +T +K+I  +  T+
Sbjct:  101 KIFVGGIRDDTDEQHLREYFQVYGDVEAAEVMEDRSTGKKRGFGFVTFSDHDTVDKVIVQKYHTI 165

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: rbm24a (RNA binding motif protein 24a [Source:NCBI gene;Acc:405801])

HSP 1 Score: 57.7658 bits (138), Expect = 9.730e-10
Identity = 30/76 (39.47%), Postives = 47/76 (61.84%), Query Frame = 3

Query:  303 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNI 527
             +IFVGG+  +TT+  L+ FF ++G I +  +I DR +G S+G YGFVT  ++ +AE+  K+     I   RK N+
Sbjct:   12 TKIFVGGLPYHTTDASLRAFFEAFGEIDEAVVITDRQSGKSRG-YGFVTMADRASAERACKD--PNPIIDGRKANV 84

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: rbmx (RNA binding motif protein X-linked [Source:NCBI gene;Acc:321860])

HSP 1 Score: 57.3806 bits (137), Expect = 3.769e-9
Identity = 33/87 (37.93%), Postives = 52/87 (59.77%), Query Frame = 3

Query:  285 IGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVR 542
            +G   P ++FVGG+  +TTE+ L+  FS YG + DV ++ DR T LS+G + FVTF N E A K  + +A   + + R + +  A +
Sbjct:    1 MGEADPGKLFVGGLNIDTTEKALEATFSKYGRVADVLLMKDRETNLSRG-FAFVTFANPEDA-KEAERDANGKVLEGRAMRVDQATK 85

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 53.9138 bits (128), Expect = 3.521e-8
Identity = 29/78 (37.18%), Postives = 52/78 (66.67%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHA 536
            +IFVGGI  +   +E + FFS +G I D +++ D+ TG S+G +GFVT+++ +  +++ +N+   + FK+RK+ I  A
Sbjct:  244 KIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSRG-FGFVTYDSADAVDRVCQNKF--IDFKDRKIEIKRA 318

HSP 2 Score: 53.1434 bits (126), Expect = 5.986e-8
Identity = 23/62 (37.10%), Postives = 44/62 (70.97%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIIND-RTGLSKGSYGFVTFENQETAEKIIKNE 488
            ++F+GG+  +TTE+ L+ +F  YG + D+KI+ D  TG S+G +GF++FE   + ++++K +
Sbjct:  160 KMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRG-FGFLSFEKPSSVDEVVKTQ 220

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: NAM8 (RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function [Source:SGD;Acc:S000001128])

HSP 1 Score: 47.7506 bits (112), Expect = 2.616e-6
Identity = 28/86 (32.56%), Postives = 49/86 (56.98%), Query Frame = 3

Query:  309 IFVGGITSNTTEEEL-KIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
            IFVG +  N TE +L ++F + Y      KI++D+ TG+SKG YGFV F N +  +++  +E + +    R + +G    +Q+ + 
Sbjct:  165 IFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKG-YGFVKFTNSD-EQQLALSEMQGVFLNGRAIKVGPTSGQQQHVS 248

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: RIE1 (Putative RNA binding protein; localizes to stress granules induced by glucose deprivation; interacts with Rbg1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003482])

HSP 1 Score: 47.7506 bits (112), Expect = 3.023e-6
Identity = 26/67 (38.81%), Postives = 34/67 (50.75%), Query Frame = 3

Query:  282 KIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIK 482
            K     P  IFVGGI  + +  EL   FS YGPI  +K+I D+T      YGF+++     A   IK
Sbjct:  188 KHALTYPGNIFVGGIAKSLSIGELSFLFSKYGPILSMKLIYDKTKGEPNGYGFISYPLGSQASLCIK 254

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO40536 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6X1])

HSP 1 Score: 81.6481 bits (200), Expect = 3.373e-18
Identity = 42/86 (48.84%), Postives = 61/86 (70.93%), Query Frame = 3

Query:  294 LIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIIND-RTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 548
            + P R+FVGG+   TTE EL+ FFS++GP+ DV+I+ D RTGL+KG +GF+TF  +E A+K+I  E   + FK R L +  A+RK+
Sbjct:   14 IYPTRVFVGGLARGTTELELETFFSNFGPVADVRIVCDRRTGLNKG-FGFITFSLEEPAKKLI--EQNNIDFKGRSLRLRQAIRKK 96

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO45185 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC5])

HSP 1 Score: 78.5666 bits (192), Expect = 7.140e-17
Identity = 42/91 (46.15%), Postives = 58/91 (63.74%), Query Frame = 3

Query:  300 PNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQFYI 572
            PNRIFVGG+   TT  EL+  F SYG ++DVKI  D  G+S+G YGFVTF   + A+K+ K    T+ +K ++L IG A RK +F    ++
Sbjct:    9 PNRIFVGGVAFQTTAIELRELFESYGAVRDVKIARDGEGVSRG-YGFVTFFRDDDAKKVFK--LGTVFYKGKRLVIGEAYRKLQFTYHSHV 96

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO43157 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZJ6])

HSP 1 Score: 75.0998 bits (183), Expect = 1.015e-15
Identity = 39/88 (44.32%), Postives = 57/88 (64.77%), Query Frame = 3

Query:  285 IGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 548
            +G   PN+IFVGG+   TT EEL  FF+++G + + K+I D  G+SKG YGFV+F +QE    +      TL  + +KLN+G AV+K+
Sbjct:    7 LGKRYPNKIFVGGLPPLTTAEELANFFANFGHVVESKVIFDHDGISKG-YGFVSFRSQEDVSCV--KAMGTLFLRNKKLNLGPAVKKE 91

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO31802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW5])

HSP 1 Score: 65.0846 bits (157), Expect = 1.568e-13
Identity = 31/58 (53.45%), Postives = 40/58 (68.97%), Query Frame = 3

Query:  297 IPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAE 470
            I  RIFV G    TTE EL+ FF  YG +K+ KI+ D+ G+SKG Y F+TFE+QE A+
Sbjct:    6 ISKRIFVKGFNRETTESELRAFFEEYGVVKESKIVRDKHGVSKG-YAFITFESQEVAD 62

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO49349 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG33])

HSP 1 Score: 56.6102 bits (135), Expect = 1.753e-9
Identity = 29/69 (42.03%), Postives = 46/69 (66.67%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKE 512
            +IF+GG+  NTTEE LK +FS +G I D  +I  R G S+G +GFVT+E+ ++  +++K +   L  +E
Sbjct:    1 KIFIGGLNWNTTEEGLKDYFSQWGTIVDC-VIMKRDGRSRG-FGFVTYESSDSVNEVLKKKDHVLDDRE 67

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: boll (boule homolog, RNA binding protein [Source:NCBI gene;Acc:100302724])

HSP 1 Score: 84.7297 bits (208), Expect = 2.296e-17
Identity = 41/88 (46.59%), Postives = 60/88 (68.18%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            GT+IPNRIFVGG+    TE  L   FS YG + +VKI+ +R+G+SKG YGFVTFE  E    I+ ++A  + ++++K +I  AV+K +
Sbjct:   35 GTIIPNRIFVGGVDYKVTENHLHHIFSHYGTVTEVKIVTNRSGMSKG-YGFVTFEAPEDVVNIL-SKANRICYRDKKFSISQAVQKSQ 120

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: dazl (deleted in azoospermia like [Source:NCBI gene;Acc:100049418])

HSP 1 Score: 64.6994 bits (156), Expect = 1.783e-11
Identity = 41/88 (46.59%), Postives = 54/88 (61.36%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G L PN +FVGGI     E E+K FF+ YG +++VKII  R GL KG YGFV F N++    I     + +IF  RKL +G A+ K+K
Sbjct:   27 GKLTPNSLFVGGIDMKVDENEIKEFFARYGSVREVKIIRYRGGLCKG-YGFVYF-NEDV--DIQSIIEQQIIFMGRKLKLGPAILKEK 110

[Close]

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G L PN +FVGGI     E E+K FF+ YG +++VKII  R GL KG YGFV F N++    I     + +IF  RKL +G A+ K+K
Sbjct:   27 GKLTPNSLFVGGIDMKVDENEIKEFFARYGSVREVKIIRYRGGLCKG-YGFVYF-NEDV--DIQSIIEQQIIFMGRKLKLGPAILKEK 110

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: dazl (deleted in azoospermia like [Source:NCBI gene;Acc:100049418])

HSP 1 Score: 64.3142 bits (155), Expect = 2.013e-11
Identity = 41/88 (46.59%), Postives = 54/88 (61.36%), Query Frame = 3

Query:  288 GTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            G L PN +FVGGI     E E+K FF+ YG +++VKII  R GL KG YGFV F N++    I     + +IF  RKL +G A+ K+K
Sbjct:   27 GKLTPNSLFVGGIDMKVDENEIKEFFARYGSVREVKIIRYRGGLCKG-YGFVYF-NEDV--DIQSIIEQQIIFMGRKLKLGPAILKEK 110

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: rbm24b (RNA-binding protein 24 [Source:NCBI gene;Acc:101161576])

HSP 1 Score: 54.6842 bits (130), Expect = 4.408e-8
Identity = 27/87 (31.03%), Postives = 53/87 (60.92%), Query Frame = 3

Query:  303 NRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE 560
             +IFVGG+  +TT+  L+ +F  +G I++  +I DR TG S+G YGFVT  ++ +A++  K+    +  ++  +N+ +   K + ++
Sbjct:   12 TKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRG-YGFVTMADRASADRACKDPNPIIDGRKANVNLAYLGAKPRVIQ 97

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000018666.1 (SMESG000018666.1)

HSP 1 Score: 226.098 bits (575), Expect = 2.166e-75
Identity = 124/129 (96.12%), Postives = 125/129 (96.90%), Query Frame = 3

Query:  177 STDSQLTPKVDTLAQEFQVSLXXXXXXXXXXXXXPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLEQ 563
            STDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ    +
Sbjct:    2 STDSQLTPKVDTLAQEFQVSLAAVNQATMTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQHLFPR 130

HSP 2 Score: 76.6406 bits (187), Expect = 2.166e-75
Identity = 36/38 (94.74%), Postives = 37/38 (97.37%), Query Frame = 2

Query:  542 KTEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQ 655
            + EISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQ
Sbjct:  130 RQEISGTVLYNGPVPYALQNGLTLFQVPGQDYSVLASQ 167

HSP 3 Score: 131.339 bits (329), Expect = 3.571e-33
Identity = 97/97 (100.00%), Postives = 97/97 (100.00%), Query Frame = 1

Query: 1183 SPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNXXXXXXXXXXXXWYTLAGLTAAPXXXXXXXXXXXXXXXAQTLRWAATTGSQ 1473
            SPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNGPGSAGSAAAAPWYTLAGLTAAPQSSSQISSNNSSNSIAQTLRWAATTGSQ
Sbjct:  168 SPQYATMMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNGPGSAGSAAAAPWYTLAGLTAAPQSSSQISSNNSSNSIAQTLRWAATTGSQ 264

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000061507.1 (SMESG000061507.1)

HSP 1 Score: 134.035 bits (336), Expect = 4.561e-35
Identity = 64/89 (71.91%), Postives = 73/89 (82.02%), Query Frame = 3

Query:  282 KIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQ 548
            KI TLIPNRIFVGG   NTTEEELK FF  YG IKDVKII D+ G +KGSYGFVTF +QE AE+II  +AETL+F++RKLNIG AV+KQ
Sbjct:   24 KISTLIPNRIFVGGFPQNTTEEELKSFFCKYGEIKDVKIIPDKAGQAKGSYGFVTFASQEVAERIITEQAETLVFRDRKLNIGRAVKKQ 112

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000061507.1 (SMESG000061507.1)

HSP 1 Score: 99.3673 bits (246), Expect = 4.296e-25
Identity = 49/66 (74.24%), Postives = 53/66 (80.30%), Query Frame = 3

Query:  282 KIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDRTGLSKGSYGFVTFENQETAEKII 479
            KI TLIPNRIFVGG   NTTEEELK FF  YG IKDVKII D+ G +KGSYGFVTF +QE AE+II
Sbjct:   24 KISTLIPNRIFVGGFPQNTTEEELKSFFCKYGEIKDVKIIPDKAGQAKGSYGFVTFASQEVAERII 89

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000006741.1 (SMESG000006741.1)

HSP 1 Score: 64.3142 bits (155), Expect = 4.682e-12
Identity = 35/83 (42.17%), Postives = 51/83 (61.45%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            +IFVGG+  +TT+E L++FF  +GPI++  +I DR +G S+G YGFVT  N E A + I N    +    RK N+  A+   K
Sbjct:   35 KIFVGGLPYHTTDESLRVFFECFGPIEEAVVITDRQSGKSRG-YGFVTMVNCEDAYRAISNPNPCI--DGRKANVNLAILGAK 114

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000006741.1 (SMESG000006741.1)

HSP 1 Score: 65.0846 bits (157), Expect = 1.905e-11
Identity = 35/83 (42.17%), Postives = 51/83 (61.45%), Query Frame = 3

Query:  306 RIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR-TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQK 551
            +IFVGG+  +TT+E L++FF  +GPI++  +I DR +G S+G YGFVT  N E A + I N    +    RK N+  A+   K
Sbjct:   35 KIFVGGLPYHTTDESLRVFFECFGPIEEAVVITDRQSGKSRG-YGFVTMVNCEDAYRAISNPNPCI--DGRKANVNLAILGAK 114

The following BLAST results are available for this feature:

BLAST of RRM domain-containing protein vs. Ensembl Human
BLAST of RRM domain-containing protein vs. Ensembl Celegans
BLAST of RRM domain-containing protein vs. Ensembl Fly
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
BLAST of RRM domain-containing protein vs. Ensembl Mouse
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
BLAST of RRM domain-containing protein vs. TrEMBL
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
BLAST of RRM domain-containing protein vs. Ensembl Yeast
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
BLAST of RRM domain-containing protein vs. Ensembl Medaka
BLAST of RRM domain-containing protein vs. Planmine SMEST

BLAST of RRM domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
BOLL	7.571e-30	63.74	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
BOLL	7.571e-30	63.74	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
BOLL	8.960e-30	63.74	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
BOLL	2.516e-29	63.74	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
DAZL	1.042e-17	46.67	deleted in azoospermia like [Source:HGNC Symbol;Ac...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
daz-1	2.083e-18	44.44	DAZ protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q2...	[more]
sup-12	1.574e-7	33.77	SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189]	[more]
msi-1	2.166e-7	32.20	MuSashI (Fly neural) family; Neural RNA-binding pr...	[more]
sup-12	5.329e-7	33.78	SUPpressor [Source:UniProtKB/TrEMBL;Acc:O45189]	[more]
H28G03.1	5.916e-7	33.85	pep chromosome:WBcel235:X:5216363:5219095:1 gene:W...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bol	7.065e-26	54.95	gene:FBgn0011206 transcript:FBtr0076539	[more]
bol	7.065e-26	54.95	gene:FBgn0011206 transcript:FBtr0076541	[more]
bol	1.142e-25	54.95	gene:FBgn0011206 transcript:FBtr0076538	[more]
bol	1.142e-25	54.95	gene:FBgn0011206 transcript:FBtr0344979	[more]
bol	1.142e-25	54.95	gene:FBgn0011206 transcript:FBtr0076540	[more]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dazl	3.537e-13	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	6.195e-13	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	6.816e-13	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	7.383e-13	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
dazl	9.514e-13	40.91	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dazl	4.230e-15	45.45	deleted in azoospermia-like [Source:NCBI gene;Acc:...	[more]
deup1	2.331e-8	37.68	deuterosome assembly protein 1 [Source:Xenbase;Acc...	[more]
rbm24	2.524e-8	32.18	RNA binding motif protein 24 [Source:NCBI gene;Acc...	[more]
nxph2	2.920e-8	33.33	neurexophilin 2 [Source:Xenbase;Acc:XB-GENE-951506...	[more]
hnrnpa2b1	1.071e-7	36.92	heterogeneous nuclear ribonucleoprotein A2/B1 [Sou...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Boll	1.446e-30	62.64	boule homolog, RNA binding protein [Source:MGI Sym...	[more]
Boll	1.532e-29	62.64	boule homolog, RNA binding protein [Source:MGI Sym...	[more]
Boll	1.704e-29	62.64	boule homolog, RNA binding protein [Source:MGI Sym...	[more]
Dazl	9.096e-18	46.67	deleted in azoospermia-like [Source:MGI Symbol;Acc...	[more]
Dazl	4.614e-17	47.13	deleted in azoospermia-like [Source:MGI Symbol;Acc...	[more]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8WP23\|BOLL_MACFA	3.391e-29	63.74	Protein boule-like OS=Macaca fascicularis OX=9541 ...	[more]
sp\|Q8N9W6\|BOLL_HUMAN	3.636e-29	63.74	Protein boule-like OS=Homo sapiens OX=9606 GN=BOLL...	[more]
sp\|Q924M5\|BOLL_MOUSE	1.059e-28	62.64	Protein boule-like OS=Mus musculus OX=10090 GN=Bol...	[more]
sp\|Q24207\|BOULE_DROME	1.145e-24	54.95	Protein boule OS=Drosophila melanogaster OX=7227 G...	[more]
sp\|Q20870\|DAZ1_CAEEL	2.612e-17	44.44	DAZ protein 1 OS=Caenorhabditis elegans OX=6239 GN...	[more]

BLAST of RRM domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A172RVQ0	3.503e-84	96.64	Boule 1 RNA-binding protein OS=Schmidtea mediterra...	[more]
A0A3P6SII3	5.388e-42	77.89	RRM domain-containing protein (Fragment) OS=Diboth...	[more]
A0A5K3F9R3	6.169e-42	69.64	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A564XYF3	7.136e-42	74.76	RRM domain-containing protein OS=Hymenolepis dimin...	[more]
A0A5K4EPW2	2.331e-41	80.65	Boule-related OS=Schistosoma mansoni OX=6183 PE=4 ...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000005184.2	8.302e-25	56.32	pep primary_assembly:Astyanax_mexicanus-2.0:10:775...	[more]
dazl	2.201e-13	42.05	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
ENSAMXT00000016054.2	1.815e-8	33.72	RNA binding motif protein 38 [Source:NCBI gene;Acc...	[more]
rbm24a	4.056e-8	31.03	RNA binding motif protein 24 [Source:NCBI gene;Acc...	[more]
rbm24a	4.749e-8	31.03	RNA binding motif protein 24 [Source:NCBI gene;Acc...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
BOLL	3.416e-30	62.64	boule homolog, RNA binding protein [Source:HGNC Sy...	[more]
HNRNPA0	4.728e-10	38.46	heterogeneous nuclear ribonucleoprotein A0 [Source...	[more]
HNRNPA0	7.791e-10	36.92	heterogeneous nuclear ribonucleoprotein A0 [Source...	[more]
rbm24a	9.730e-10	39.47	RNA binding motif protein 24a [Source:NCBI gene;Ac...	[more]
rbmx	3.769e-9	37.93	RNA binding motif protein X-linked [Source:NCBI ge...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
HRP1	3.521e-8	37.18	Subunit of cleavage factor I; cleavage factor I is...	[more]
NAM8	2.616e-6	32.56	RNA binding protein, component of the U1 snRNP pro...	[more]
RIE1	3.023e-6	38.81	Putative RNA binding protein; localizes to stress ...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40536	3.373e-18	48.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45185	7.140e-17	46.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43157	1.015e-15	44.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31802	1.568e-13	53.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49349	1.753e-9	42.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
boll	2.296e-17	46.59	boule homolog, RNA binding protein [Source:NCBI ge...	[more]
dazl	1.783e-11	46.59	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
dazl	1.783e-11	46.59	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
dazl	2.013e-11	46.59	deleted in azoospermia like [Source:NCBI gene;Acc:...	[more]
rbm24b	4.408e-8	31.03	RNA-binding protein 24 [Source:NCBI gene;Acc:10116...	[more]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000018666.1	2.166e-75	96.12	SMESG000018666.1	[more]
SMESG000061507.1	4.561e-35	71.91	SMESG000061507.1	[more]
SMESG000061507.1	4.296e-25	74.24	SMESG000061507.1	[more]
SMESG000006741.1	4.682e-12	42.17	SMESG000006741.1	[more]
SMESG000006741.1	1.905e-11	42.17	SMESG000006741.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30011677 ID=SMED30011677|Name=RRM domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1524bp
AACCAATCAATGCTAAGGATTGAAAATTAGTGTGTATGCAAACAAAATGG
TAAGTCTTTGTTAAATTTCATAACTTTATTTATAATGAAATCAATCAATA
TCAGTATGATTCATCGCGTATCCTTAATTTTTTTATCAAAATTTAAAATC
TAACCGCCATTTTATTTTTTAAACAGTCAACTGATAGTCAACTTACGCCT
AAAGTAGATACACTAGCTCAAGAATTTCAAGTTTCACTTGCTGCTGTTAA
TCAAGCAACGATGACTGCTGCTGCAAACCCTAAAATCGGTACTCTGATAC
CAAATCGAATATTTGTTGGTGGAATCACGTCAAATACGACAGAAGAAGAA
TTGAAAATATTTTTTTCAAGTTACGGTCCAATTAAGGATGTTAAAATAAT
AAATGATCGTACTGGATTATCCAAAGGGAGTTATGGGTTTGTTACATTTG
AAAATCAAGAAACTGCTGAAAAAATAATCAAAAATGAAGCAGAAACACTG
ATATTTAAGGAACGGAAATTAAACATAGGACACGCTGTTAGAAAACAGAA
ATTTCTGGAACAGTTTTATATAATGGACCCGTGCCTTATGCTTTACAAAA
TGGTTTAACATTGTTCCAAGTTCCTGGACAAGACTATTCAGTTTTAGCGT
CACAAGTGAGTAATTTTAAAATTACATTTATCAATCTCTTTTATTAGCTT
TGATAATGTTTTGGCTACTTCAAGTTAAATTATAATCATTTCAAAAAATA
TGAAGAGAACGTAATAAAATATTCTTATGAAAAGTTCTTATTTTCAAAAT
TGGATAATTTTAAATAATGCCATGATCCAAATTGTCACATACTTTTTCAG
TTCCGAGCTTTAGTATTTTTACTTGATTTTGAGATCAAATGTCTCTTATA
AAAAATTCATTTGGGATTATTCGTGTTTTTCATAATCTTTTAGTTATTGA
ATAAATATACTTCTGATTTTAGATTCAGAAAATAAAAAAATTTGTAATAA
AGTAATAAACACGTAAGTCATTGCTTATAAAAAATCCCACACTGGTTCTT
TTAGAGTAACTAGGTAGATGCTCACTGTAGGAAAAAAACTACAAGTAGTG
CTTTTTATAGCTTACTCTACAGCATTCTTGAAATCGAAAAAATACGATAC
TGTTTCATTTTTTAAAAATCAAGTTTTATATTTCTCCTCAATACGCAACT
ATGATGTTACCTCAACCGACTACGGCTATGTATTTACCGCAACCACAATA
TGCTTATCAAACGCCTACTGCTGTGATTCCTTCCCCTAACAACGGACAAC
AAGTAACATTTACTCAAAACGGTCCTGGATCAGCAGGATCAGCAGCTGCT
GCACCATGGTACACTTTAGCTGGATTAACGGCAGCACCACAATCATCTTC
ACAAATTTCAAGCAACAATAGTTCAAATTCAATTGCTCAAACTTTAAGAT
GGGCGGCTACAACTGGATCACAAGTTTATAATATATTAAACATTTTAATC
TATTAGGTGCTTTAGAGTCCTCCG

protein sequence of SMED30011677-orf-1

>SMED30011677-orf-1 ID=SMED30011677-orf-1|Name=SMED30011677-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=116bp
MTAAANPKIGTLIPNRIFVGGITSNTTEEELKIFFSSYGPIKDVKIINDR
TGLSKGSYGFVTFENQETAEKIIKNEAETLIFKERKLNIGHAVRKQKFLE
QFYIMDPCLMLYKMV*

protein sequence of SMED30011677-orf-2

>SMED30011677-orf-2 ID=SMED30011677-orf-2|Name=SMED30011677-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=102bp
MMLPQPTTAMYLPQPQYAYQTPTAVIPSPNNGQQVTFTQNGPGSAGSAAA
APWYTLAGLTAAPQSSSQISSNNSSNSIAQTLRWAATTGSQVYNILNILI
Y*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0000204	ovary
PLANA:0000208	testis
PLANA:0000219	spermatogonial stem cell
PLANA:0000220	spermatogonium
PLANA:0000221	spermatocyte
PLANA:0000222	spermatid
PLANA:0000422	tail stripe
PLANA:0000429	neoblast
PLANA:0002089	reproductive organ
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0002142	parenchyma
PLANA:0003304	testis primordium

Vocabulary: **INTERPRO**
Term	Definition
IPR037366	BOULE/DAZ
IPR035979	RBD_domain_sf
IPR000504	RRM_dom
IPR012677	Nucleotide-bd_a/b_plait_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000504	RNA recognition motif domain	SMART	SM00360	rrm1_1	coord: 16..90 e-value: 1.5E-19 score: 81.0
IPR000504	RNA recognition motif domain	PFAM	PF00076	RRM_1	coord: 17..78 e-value: 6.9E-19 score: 67.4
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 15..94 score: 16.261
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 9..103 e-value: 1.4E-25 score: 91.3
None	No IPR available	PANTHER	PTHR11176:SF14	PROTEIN BOULE	coord: 4..99
IPR037366	BOULE/DAZ family	PANTHER	PTHR11176	BOULE-RELATED	coord: 4..99
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 15..97