Derlin

Overview
NameDerlin
Smed IDSMED30011670
Length (bp)959
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Derlin (SMED30011670) t-SNE clustered cells

Violin plots show distribution of expression levels for Derlin (SMED30011670) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Derlin (SMED30011670) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Derlin (SMED30011670) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30011670

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30011670SMESG000024268.1 dd_Smed_v4_2882_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30011670SMESG000024268.1 dd_Smed_v4_2882_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011670SMESG000024268.1 Contig47490uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011670SMESG000024268.1 Contig47490newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
central nervous systemSMED30011670SMESG000024268.1 DN304569ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30011670SMESG000024268.1 DN304569ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
vitelline glandSMED30011670SMESG000024268.1 DN304569ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Derlin vs. Ensembl Human
Match: DERL1 (derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454])

HSP 1 Score: 299.671 bits (766), Expect = 1.614e-101
Identity = 144/249 (57.83%), Postives = 184/249 (73.90%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P  +FL    F+ +FQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
[Close]
BLAST of Derlin vs. Ensembl Human
Match: DERL1 (derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454])

HSP 1 Score: 264.233 bits (674), Expect = 8.003e-88
Identity = 132/249 (53.01%), Postives = 168/249 (67.47%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P  +FL    F+ +FQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G                     YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGG--------------------SYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 230
[Close]
BLAST of Derlin vs. Ensembl Human
Match: DERL1 (derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454])

HSP 1 Score: 174.096 bits (440), Expect = 1.177e-53
Identity = 83/150 (55.33%), Postives = 109/150 (72.67%), Query Frame = 3 
Query:  390 MLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            ML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    1 MLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 150
[Close]
BLAST of Derlin vs. Ensembl Human
Match: DERL1 (derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454])

HSP 1 Score: 174.096 bits (440), Expect = 1.177e-53
Identity = 83/150 (55.33%), Postives = 109/150 (72.67%), Query Frame = 3 
Query:  390 MLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            ML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    1 MLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 150
[Close]
BLAST of Derlin vs. Ensembl Human
Match: DERL2 (derlin 2 [Source:HGNC Symbol;Acc:HGNC:17943])

HSP 1 Score: 117.472 bits (293), Expect = 8.950e-31
Identity = 72/200 (36.00%), Postives = 110/200 (55.00%), Query Frame = 3 
Query:  111 YRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFM 707
            Y  IP VS+ + T  VL     +   + P+ ++       + FQIWR IT  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F    + + G    L  L +   I ++YVW + N  V + F+    F+A +LPW+L+ F++++      DLLGI VGH+YFFL   +P + GG   L+TP  +
Sbjct:   10 YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSIL 205
[Close]
BLAST of Derlin vs. Ensembl Celegans
Match: cup-2 (Derlin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q93561])

HSP 1 Score: 249.98 bits (637), Expect = 1.724e-82
Identity = 124/247 (50.20%), Postives = 166/247 (67.21%), Query Frame = 3 
Query:   96 DIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLG 836
            D+  +   IP V++YWF  S + PL G+FGF++   MFL W   + KFQ WRP+TAL YYPVTP TGFH+L+  YFLY+YS  LE+ T+ G+ ADYLFMLIFNW     +  A  +Y L+EPM+ISVLYVWCQ+NKD IV FWFG +F A YLPW+L  FN +++GGG  +L+GI+VGH YFF+  KYP E+G ++ + TP+F+++ +P+  GG+   G   + R AR        P   G G  LG
Sbjct:    2 DLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQFWRPLTALIYYPVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCSGLCMALDIYFLLEPMVISVLYVWCQVNKDTIVSFWFGMRFPARYLPWVLWGFNAVLRGGGTNELVGILVGHAYFFVALKYPDEYGVDL-ISTPEFLHRLIPDEDGGIH--GQDGNIRGARQQPRGHQWP--GGVGARLG 243
[Close]
BLAST of Derlin vs. Ensembl Celegans
Match: cup-2 (Derlin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q93561])

HSP 1 Score: 249.98 bits (637), Expect = 1.724e-82
Identity = 124/247 (50.20%), Postives = 166/247 (67.21%), Query Frame = 3 
Query:   96 DIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLG 836
            D+  +   IP V++YWF  S + PL G+FGF++   MFL W   + KFQ WRP+TAL YYPVTP TGFH+L+  YFLY+YS  LE+ T+ G+ ADYLFMLIFNW     +  A  +Y L+EPM+ISVLYVWCQ+NKD IV FWFG +F A YLPW+L  FN +++GGG  +L+GI+VGH YFF+  KYP E+G ++ + TP+F+++ +P+  GG+   G   + R AR        P   G G  LG
Sbjct:    2 DLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQFWRPLTALIYYPVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCSGLCMALDIYFLLEPMVISVLYVWCQVNKDTIVSFWFGMRFPARYLPWVLWGFNAVLRGGGTNELVGILVGHAYFFVALKYPDEYGVDL-ISTPEFLHRLIPDEDGGIH--GQDGNIRGARQQPRGHQWP--GGVGARLG 243
[Close]
BLAST of Derlin vs. Ensembl Celegans
Match: R151.6 (Derlin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21997])

HSP 1 Score: 93.9745 bits (232), Expect = 2.111e-22
Identity = 58/205 (28.29%), Postives = 108/205 (52.68%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFM 707
            N +      +P V++++    VL        F+ P+ ++  W   I K+Q WR IT+  ++     +   +L N+ F Y Y   LE  +F G+ AD+++M +F  + +++ G    +  L +   I ++Y+W + N  + + F+    F A YLPW+L+ F++++      D +GI  GH+YFFL   +P +  G  +L+TPQ++
Sbjct:    2 NGVVAALEEMPPVTRFYTGACVLLTTAVHLEFVTPFHLYFNWELIIRKYQFWRLITSFCFFGSFGFS---FLFNMIFTYRYCMMLEEGSFRGRRADFVYMFLFGAVLMILSGIFVQILFLGQAFTIMLVYIWSRRNPMIQMNFFGVLTFTAPYLPWVLLLFSLLLGNNAVVDFMGIACGHIYFFLEDVFPFQEHGKRFLKTPQWL 203
[Close]
BLAST of Derlin vs. Ensembl Fly
Match: Der-1 (gene:FBgn0267972 transcript:FBtr0077813)

HSP 1 Score: 211.846 bits (538), Expect = 1.955e-67
Identity = 109/247 (44.13%), Postives = 156/247 (63.16%), Query Frame = 3 
Query:   96 DIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLG 836
            D G WYRS+P  ++YW T +V+  +  +F  +  + + L  +    K Q+WR +T+LF +P++  T FH+LIN +F+  YS++LE   +   PADYL++LI + +   I G    +Y LM+ +++++ Y+WCQLNKDV V FWFGT+FKAMYLPW+L AF  I        L+GI VGH+Y+F  F+Y Q+ GG   L TPQF+ + +P+  GG  GFG+PP SRA    AT S      GRG TLG
Sbjct:    2 DAGVWYRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQLWRCMTSLFVFPISSNTAFHFLINCFFIVQYSSKLEKDQYSRSPADYLYLLIVSAVLANIGGMIFNVYFLMDTLVLAITYIWCQLNKDVTVSFWFGTRFKAMYLPWVLAAFEFIFH-FSLASLVGIFVGHVYYFFKFQYSQDLGGTPLLETPQFLKRLVPDVSGGFGGFGLPPESRAPPRQATESPW----GRGMTLG 243
[Close]
BLAST of Derlin vs. Ensembl Fly
Match: Der-1 (gene:FBgn0267972 transcript:FBtr0334758)

HSP 1 Score: 211.846 bits (538), Expect = 1.955e-67
Identity = 109/247 (44.13%), Postives = 156/247 (63.16%), Query Frame = 3 
Query:   96 DIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLG 836
            D G WYRS+P  ++YW T +V+  +  +F  +  + + L  +    K Q+WR +T+LF +P++  T FH+LIN +F+  YS++LE   +   PADYL++LI + +   I G    +Y LM+ +++++ Y+WCQLNKDV V FWFGT+FKAMYLPW+L AF  I        L+GI VGH+Y+F  F+Y Q+ GG   L TPQF+ + +P+  GG  GFG+PP SRA    AT S      GRG TLG
Sbjct:    2 DAGVWYRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQLWRCMTSLFVFPISSNTAFHFLINCFFIVQYSSKLEKDQYSRSPADYLYLLIVSAVLANIGGMIFNVYFLMDTLVLAITYIWCQLNKDVTVSFWFGTRFKAMYLPWVLAAFEFIFH-FSLASLVGIFVGHVYYFFKFQYSQDLGGTPLLETPQFLKRLVPDVSGGFGGFGLPPESRAPPRQATESPW----GRGMTLG 243
[Close]
BLAST of Derlin vs. Ensembl Fly
Match: Der-2 (gene:FBgn0038438 transcript:FBtr0083307)

HSP 1 Score: 105.916 bits (263), Expect = 1.886e-26
Identity = 64/213 (30.05%), Postives = 106/213 (49.77%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTI 731
            N + ++Y  IP V++ + T  VL  L      + P  ++   T  + KFQIWR  T   Y+      G  +  N+ F Y Y   LE  +F G+ +D++ M IF  + +   G    L  L +   + ++YVW + N  V + F+    F+A YLPW+L+  +MI+    + D++G+ VGH+Y+ L   YP    G   ++TP F+ +     I
Sbjct:    2 NALRQFYLEIPVVTRAYTTVCVLTTLAVHLDLVSPLQLYFNPTLIVRKFQIWRLATTFLYFGTI---GISFFFNMVFTYRYCRMLEDGSFRGRSSDFVMMFIFGGVLMTFFGIFVNLLFLGQAFTLMLVYVWSRRNPLVPMNFFGVLNFQAPYLPWVLLCCSMILGNTVWVDVIGMGVGHIYYVLEDVYPTLSNGYRLIKTPYFLKRLFNEHI 211
[Close]
BLAST of Derlin vs. Ensembl Zebrafish
Match: derl1 (derlin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2793])

HSP 1 Score: 290.041 bits (741), Expect = 1.078e-97
Identity = 136/226 (60.18%), Postives = 172/226 (76.11%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSR 770
            +DIG+W+++IPF+++YWF GS+  PL GK G + P  + L    F  KFQIWRPITA  Y+PV P TGF YL+NLYFLY YS+RLET  F G+PADY+FML+FNW+C+VI G    + LLM P+I+SVLYVW QLN+D IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMFKYP + GG  +L TPQF+Y+  PN  GG+SGFG+PPS R
Sbjct:    2 SDIGDWFKNIPFITRYWFAGSIAVPLIGKLGLIGPMYLVLWPEAFFHKFQIWRPITATLYFPVGPGTGFLYLVNLYFLYQYSSRLETGAFDGRPADYMFMLLFNWICIVITGLMMDMQLLMIPLIMSVLYVWAQLNRDTIVSFWFGTRFKACYLPWVILGFNYIIGGSVVNELIGNLVGHLYFFLMFKYPMDLGGRSFLSTPQFLYQMFPNRRGGVSGFGVPPSRR 227
[Close]
BLAST of Derlin vs. Ensembl Zebrafish
Match: derl2 (derlin 2 [Source:ZFIN;Acc:ZDB-GENE-050522-90])

HSP 1 Score: 129.413 bits (324), Expect = 2.063e-35
Identity = 78/230 (33.91%), Postives = 125/230 (54.35%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSR 770
            M+   I + Y  IP V++ + T  VL     +   + P+ ++      +  +Q+WR IT  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F  L + I G    L  L +   I ++Y+W + N +V + F+    F+A +LPW+L+ F++++      DLLGI VGH+Y+FL   +P + GG  WLRTP  + K L +T    + +   P  R
Sbjct:    1 MAYQTIRQEYLQIPVVTRAYTTACVLTTAAVQLELITPFQLYFNPDLILRNYQVWRLITNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGLLMTIFGTFVNLVFLGQAFTIMLVYIWSRRNPNVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHVYYFLEDVFPNQPGGGRWLRTPSIL-KMLFDTPEEDANYNPLPEDR 225
[Close]
BLAST of Derlin vs. Ensembl Zebrafish
Match: derl3 (derlin 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1324])

HSP 1 Score: 119.783 bits (299), Expect = 1.150e-31
Identity = 71/211 (33.65%), Postives = 120/211 (56.87%), Query Frame = 3 
Query:   90 GNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFL 719
             N + + Y  IP V++ + T  VL     +   + P+ ++      ++K+QIWR IT  LF+ P+    GF +L N+ FLY Y   LE  +F G+ AD+++M +F  + + + G  + L+ L +   I ++YVW + N  V + F+    F+A +LPW+L+ F++++      DLLGI VGH+Y+FL   +P + GG   L TP  +++FL
Sbjct:    2 ANSVTQEYMQIPAVTRAYTTACVLTTAAVQLELITPFQLYFNPDLILKKYQIWRLITNFLFFGPL----GFSFLFNMIFLYRYCRMLEEGSFRGRTADFVYMFLFGGVLMTLFGLFSNLFFLGQAFTIMLVYVWSRRNPFVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIVIDLLGIGVGHIYYFLEDVFPNQPGGRKLLATPG-IFRFL 207
[Close]
BLAST of Derlin vs. Ensembl Zebrafish
Match: derl3 (derlin 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1324])

HSP 1 Score: 119.398 bits (298), Expect = 1.332e-31
Identity = 69/204 (33.82%), Postives = 115/204 (56.37%), Query Frame = 3 
Query:   90 GNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTP 698
             N + + Y  IP V++ + T  VL     +   + P+ ++      ++K+QIWR IT  LF+ P+    GF +L N+ FLY Y   LE  +F G+ AD+++M +F  + + + G  + L+ L +   I ++YVW + N  V + F+    F+A +LPW+L+ F++++      DLLGI VGH+Y+FL   +P + GG   L TP
Sbjct:    2 ANSVTQEYMQIPAVTRAYTTACVLTTAAVQLELITPFQLYFNPDLILKKYQIWRLITNFLFFGPL----GFSFLFNMIFLYRYCRMLEEGSFRGRTADFVYMFLFGGVLMTLFGLFSNLFFLGQAFTIMLVYVWSRRNPFVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIVIDLLGIGVGHIYYFLEDVFPNQPGGRKLLATP 201
[Close]
BLAST of Derlin vs. Ensembl Xenopus
Match: derl1 (lipoxygenase homology domain-containing protein 1-like [Source:Xenbase;Acc:XB-GENE-6032685])

HSP 1 Score: 278.87 bits (712), Expect = 2.574e-93
Identity = 141/250 (56.40%), Postives = 185/250 (74.00%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPP-SSRAARGDATSSSRPRFPGRGQTLGD 839
            +D+G+W+RSIPF+++YWF  S+ FPL G+ G ++   + L    F+ KFQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADY+FML+FNW+C+VI G    + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLY+FLMFKYP + GG  +L TPQF+Y++ P+  GG SGFG+PP S+R    +   + R    G+G  LGD
Sbjct:    2 SDLGDWFRSIPFITRYWFAASIAFPLIGRLGLINGGNLILWPEYFLHKFQIWRPITATFYFPVGPKTGFLYLVNLYFLYQYSTRLETGAFDGRPADYVFMLLFNWICIVITGVIMNMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNFIISGSVVDELIGNLVGHLYYFLMFKYPMDLGGRSFLTTPQFLYRWFPSRRGGGSGFGVPPASARRVEDEQPGAGRRHNWGQGFRLGD 251
[Close]
BLAST of Derlin vs. Ensembl Xenopus
Match: derl1 (lipoxygenase homology domain-containing protein 1-like [Source:Xenbase;Acc:XB-GENE-6032685])

HSP 1 Score: 268.855 bits (686), Expect = 1.892e-89
Identity = 141/253 (55.73%), Postives = 185/253 (73.12%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLY---LLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPP-SSRAARGDATSSSRPRFPGRGQTLGD 839
            +D+G+W+RSIPF+++YWF  S+ FPL G+ G ++   + L    F+ KFQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADY+FML+FNW+C V +    P+Y   LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLY+FLMFKYP + GG  +L TPQF+Y++ P+  GG SGFG+PP S+R    +   + R    G+G  LGD
Sbjct:    2 SDLGDWFRSIPFITRYWFAASIAFPLIGRLGLINGGNLILWPEYFLHKFQIWRPITATFYFPVGPKTGFLYLVNLYFLYQYSTRLETGAFDGRPADYVFMLLFNWIC-VDVYITYPVYMLQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNFIISGSVVDELIGNLVGHLYYFLMFKYPMDLGGRSFLTTPQFLYRWFPSRRGGGSGFGVPPASARRVEDEQPGAGRRHNWGQGFRLGD 253
[Close]
BLAST of Derlin vs. Ensembl Xenopus
Match: orc6 (origin recognition complex subunit 6 [Source:Xenbase;Acc:XB-GENE-963541])

HSP 1 Score: 120.553 bits (301), Expect = 6.022e-32
Identity = 73/206 (35.44%), Postives = 113/206 (54.85%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTP 698
            M+     + Y  IP V++ + T  VL     +   + P+ ++         +QIWR +T  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F  L +VI G    L  L +   I ++YVW + N  V + F+    F+A +LPW+L+ F++++      DLLGI VGH+YFFL   +P + GG   L+TP
Sbjct:    1 MAYQTFRQEYMQIPPVTRAYTTACVLTTAVVQLELITPFQLYFNPELIFRHYQIWRLVTNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGLLMVIFGLFVNLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGGRILKTP 202
[Close]
BLAST of Derlin vs. Ensembl Mouse
Match: Derl1 (Der1-like domain family, member 1 [Source:MGI Symbol;Acc:MGI:1915069])

HSP 1 Score: 295.049 bits (754), Expect = 7.231e-100
Identity = 142/249 (57.03%), Postives = 181/249 (72.69%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P   FL    F+ +FQIWRP TA FY+PV P TGF YL+NLYFLY YSTRLE   F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFLWPEAFLYRFQIWRPFTATFYFPVGPGTGFLYLVNLYFLYQYSTRLEAGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDLIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
[Close]
BLAST of Derlin vs. Ensembl Mouse
Match: Derl2 (Der1-like domain family, member 2 [Source:MGI Symbol;Acc:MGI:2151483])

HSP 1 Score: 117.472 bits (293), Expect = 6.275e-31
Identity = 72/200 (36.00%), Postives = 110/200 (55.00%), Query Frame = 3 
Query:  111 YRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFM 707
            Y  IP VS+ + T  VL     +   + P+ ++       + FQIWR IT  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F    + + G    L  L +   I ++YVW + N  V + F+    F+A +LPW+L+ F++++      DLLGI VGH+YFFL   +P + GG   L+TP  +
Sbjct:   10 YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSIL 205
[Close]
BLAST of Derlin vs. Ensembl Mouse
Match: Derl2 (Der1-like domain family, member 2 [Source:MGI Symbol;Acc:MGI:2151483])

HSP 1 Score: 117.087 bits (292), Expect = 8.413e-31
Identity = 72/200 (36.00%), Postives = 110/200 (55.00%), Query Frame = 3 
Query:  111 YRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFM 707
            Y  IP VS+ + T  VL     +   + P+ ++       + FQIWR IT  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F    + + G    L  L +   I ++YVW + N  V + F+    F+A +LPW+L+ F++++      DLLGI VGH+YFFL   +P + GG   L+TP  +
Sbjct:   10 YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSIL 205
[Close]
BLAST of Derlin vs. Ensembl Mouse
Match: Derl3 (Der1-like domain family, member 3 [Source:MGI Symbol;Acc:MGI:1917627])

HSP 1 Score: 112.079 bits (279), Expect = 6.301e-29
Identity = 63/214 (29.44%), Postives = 113/214 (52.80%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPN 725
            M+G  +   +  +P V++ +    VL     +   L P+ ++        KFQ+WR IT   ++         +  N+ F++ Y   LE  +F G+ AD++FM +F  + + ++GF   L+ L + ++  ++YVW + +  V V F+    F+A +LPW L+ F++++     TDLLGI+VGH+Y+FL   +P + GG   L TP  +   L +
Sbjct:    1 MAGQRLAAGFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLITTFLFFGPLGFG---FFFNMLFVFRYCRMLEEGSFRGRKADFVFMFLFGGVLMTLLGFLGSLFFLGQALMAMLVYVWSRRSPHVRVNFFGLLNFQAPFLPWALMGFSLLLGNSVVTDLLGILVGHIYYFLEDVFPNQPGGKRLLLTPSVLKLLLDD 211
[Close]
BLAST of Derlin vs. Ensembl Mouse
Match: Derl3 (Der1-like domain family, member 3 [Source:MGI Symbol;Acc:MGI:1917627])

HSP 1 Score: 108.612 bits (270), Expect = 1.071e-27
Identity = 62/214 (28.97%), Postives = 113/214 (52.80%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPN 725
            M+G  +   +  +P V++ + T + +         L P+ ++        KFQ+WR IT   ++         +  N+ F++ Y   LE  +F G+ AD++FM +F  + + ++GF   L+ L + ++  ++YVW + +  V V F+    F+A +LPW L+ F++++     TDLLGI+VGH+Y+FL   +P + GG   L TP  +   L +
Sbjct:    1 MAGQRLAAGFLQVPAVTRAY-TAACVLTTAAVLELLSPFQLYFNPHLVFRKFQVWRLITTFLFFGPLGFG---FFFNMLFVFRYCRMLEEGSFRGRKADFVFMFLFGGVLMTLLGFLGSLFFLGQALMAMLVYVWSRRSPHVRVNFFGLLNFQAPFLPWALMGFSLLLGNSVVTDLLGILVGHIYYFLEDVFPNQPGGKRLLLTPSVLKLLLDD 210
[Close]
BLAST of Derlin vs. UniProt/SwissProt
Match: sp|Q9BUN8|DERL1_HUMAN (Derlin-1 OS=Homo sapiens OX=9606 GN=DERL1 PE=1 SV=1)

HSP 1 Score: 299.671 bits (766), Expect = 7.749e-101
Identity = 144/249 (57.83%), Postives = 184/249 (73.90%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P  +FL    F+ +FQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
[Close]
BLAST of Derlin vs. UniProt/SwissProt
Match: sp|Q5R9W3|DERL1_PONAB (Derlin-1 OS=Pongo abelii OX=9601 GN=DERL1 PE=2 SV=1)

HSP 1 Score: 299.671 bits (766), Expect = 8.548e-101
Identity = 144/249 (57.83%), Postives = 184/249 (73.90%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P  +FL    F+ +FQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYHYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
[Close]
BLAST of Derlin vs. UniProt/SwissProt
Match: sp|Q71SS4|DERL1_BOVIN (Derlin-1 OS=Bos taurus OX=9913 GN=DERL1 PE=2 SV=1)

HSP 1 Score: 298.13 bits (762), Expect = 3.132e-100
Identity = 144/249 (57.83%), Postives = 183/249 (73.49%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P   FL    F+ +FQIWRPITA FY+PV P TGF YL+NLYFLY YSTRLET  F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPTITRYWFAATVAVPLVGKLGLISPAYFFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
[Close]
BLAST of Derlin vs. UniProt/SwissProt
Match: sp|Q99J56|DERL1_MOUSE (Derlin-1 OS=Mus musculus OX=10090 GN=Derl1 PE=1 SV=1)

HSP 1 Score: 295.049 bits (754), Expect = 5.058e-99
Identity = 142/249 (57.03%), Postives = 181/249 (72.69%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            +DIG+W+RSIP +++YWF  +V  PL GK G + P   FL    F+ +FQIWRP TA FY+PV P TGF YL+NLYFLY YSTRLE   F G+PADYLFML+FNW+C+VI G A  + LLM P+I+SVLYVW QLN+D+IV FWFGT+FKA YLPW+++ FN II G    +L+G +VGHLYFFLMF+YP + GG  +L TPQF+Y++LP+  GG+SGFG+PP+S     D          G+G  LGD
Sbjct:    2 SDIGDWFRSIPAITRYWFAATVAVPLIGKLGIISPAYFFLWPEAFLYRFQIWRPFTATFYFPVGPGTGFLYLVNLYFLYQYSTRLEAGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDLIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
[Close]
BLAST of Derlin vs. UniProt/SwissProt
Match: sp|Q93561|DERL1_CAEEL (Derlin-1 OS=Caenorhabditis elegans OX=6239 GN=cup-2 PE=2 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 2.193e-81
Identity = 124/247 (50.20%), Postives = 166/247 (67.21%), Query Frame = 3 
Query:   96 DIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLG 836
            D+  +   IP V++YWF  S + PL G+FGF++   MFL W   + KFQ WRP+TAL YYPVTP TGFH+L+  YFLY+YS  LE+ T+ G+ ADYLFMLIFNW     +  A  +Y L+EPM+ISVLYVWCQ+NKD IV FWFG +F A YLPW+L  FN +++GGG  +L+GI+VGH YFF+  KYP E+G ++ + TP+F+++ +P+  GG+   G   + R AR        P   G G  LG
Sbjct:    2 DLENFLLGIPIVTRYWFLASTIIPLLGRFGFINVQWMFLQWDLVVNKFQFWRPLTALIYYPVTPQTGFHWLMMCYFLYNYSKALESETYRGRSADYLFMLIFNWFFCSGLCMALDIYFLLEPMVISVLYVWCQVNKDTIVSFWFGMRFPARYLPWVLWGFNAVLRGGGTNELVGILVGHAYFFVALKYPDEYGVDL-ISTPEFLHRLIPDEDGGIH--GQDGNIRGARQQPRGHQWP--GGVGARLG 243
[Close]
BLAST of Derlin vs. TrEMBL
Match: R7V7G0 (Derlin OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_179997 PE=3 SV=1)

HSP 1 Score: 351.673 bits (901), Expect = 1.017e-118
Identity = 172/254 (67.72%), Postives = 204/254 (80.31%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRA--ARGDATSSSRPRFPGRGQTLGD 839
            M+ NDIG+WYR+IP +S+YWFT SV+FPL GK G L  + M L +   +  FQ WRP+TALF+YP+TP TGFH+LINLYFLYSYSTRLET  F G+PAD LFMLIFNW+CLVIIGF   L LLM+PMI+SVLY+WCQLNKD IVQFWFGTQFKAMYLPWILVAFNMII+GGGF +LLGI+VGHLYFFL +KYPQ+FGG  +L+TPQF+YKF PN   G+SGFG+PPS+R      D  ++ R    G G TLG+
Sbjct:    1 MASNDIGDWYRNIPQISRYWFTASVVFPLLGKLGILSIFYMVLHFEMTVYGFQFWRPVTALFFYPLTPQTGFHFLINLYFLYSYSTRLETGIFFGRPADQLFMLIFNWICLVIIGFLVGLMLLMDPMILSVLYIWCQLNKDTIVQFWFGTQFKAMYLPWILVAFNMIIRGGGFNELLGIMVGHLYFFLAYKYPQDFGGRSFLQTPQFLYKFFPNQRPGVSGFGVPPSTRRRPEENDDPNARRRHAWGTGNTLGN 254
[Close]
BLAST of Derlin vs. TrEMBL
Match: C3YFB1 (Derlin OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_279759 PE=3 SV=1)

HSP 1 Score: 343.199 bits (879), Expect = 1.497e-115
Identity = 163/250 (65.20%), Postives = 200/250 (80.00%), Query Frame = 3 
Query:   87 SGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLG 836
             G+DIG+W+RSIP +++YWF  SV  PL G+ G +D  +M L W   +  FQIWRP+TALF+YP+ P TGFHYLINLYFLY+YSTRLET  F G+PADYLFMLIF WLCLVIIGF   LYLLM+PMI++VLYVWCQLN+D IV FWFGTQFKAMYLPW+LV FNMI++GGG+TDLLGI VGHLYFFLMFKYPQ+FGG  +L TP+ +Y++LPN  GG+SGFG+PP+SR        +++ +  G+G  LG
Sbjct:    3 EGSDIGDWFRSIPLITRYWFALSVALPLLGRIGLVDAMSMVLHWDMTVYHFQIWRPVTALFFYPLMPQTGFHYLINLYFLYNYSTRLETGLFDGRPADYLFMLIFQWLCLVIIGFMAELYLLMDPMILAVLYVWCQLNRDTIVSFWFGTQFKAMYLPWVLVGFNMILRGGGWTDLLGIFVGHLYFFLMFKYPQDFGGRSFLSTPEILYRYLPNRRGGVSGFGVPPASRR----RPDNNQHQGWGQGNVLG 248
[Close]
BLAST of Derlin vs. TrEMBL
Match: W4YQI8 (Derlin OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1)

HSP 1 Score: 338.191 bits (866), Expect = 1.814e-113
Identity = 162/252 (64.29%), Postives = 198/252 (78.57%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFP-GRGQTLG 836
            MS +DIG+WYR IP +++YWFTGS++ PL  +FG +   ++ L +     +FQIWR ITA+F++P+TPMTGFHYLI LYFLYSYSTRLET  F G+PADY+FMLIFNW+CLVIIGF  PL +LMEPMI+S LYVWCQLN+D IV FWFGT+FKAMYLPW+LVAFN I++GGG  +L+GIVVGHLYFFLMFKYPQ+FGG  +L TPQF+YK+ PN  GG+SGFG  PS R  R D     + R   G+G  LG
Sbjct:    1 MSQSDIGDWYRGIPQITRYWFTGSIIVPLIARFGLVSMKSLILSFELVFYRFQIWRTITAVFFFPITPMTGFHYLIQLYFLYSYSTRLETGIFDGRPADYVFMLIFNWICLVIIGFIAPLMMLMEPMILSALYVWCQLNRDTIVSFWFGTRFKAMYLPWVLVAFNWILRGGGLAELIGIVVGHLYFFLMFKYPQDFGGTAFLSTPQFLYKYFPNRRGGVSGFGEAPSFRRDRPDDRGQGQGRHNWGQGNVLG 252
[Close]
BLAST of Derlin vs. TrEMBL
Match: A0A267FI24 (Derlin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003689g1 PE=3 SV=1)

HSP 1 Score: 338.576 bits (867), Expect = 1.878e-113
Identity = 159/262 (60.69%), Postives = 198/262 (75.57%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSS----------RPRFPGRGQTLGD 839
            M+ N++ EWY ++P +S+YWFTGSV+ PL G+ G L PY+M L+W      F IWRPITAL YYP++P TGFHYLINLYFLYSYST LE+  F G PA+Y F+L+F W+CLV +G A  LYLLM+PM+++VLY+WCQLN+D IVQFWFG QFKAMYLPW+L+AFNMIIQGGGFT+LLGI+VGHLYFFL FKYPQ+ GG   +  P+F+Y+ LP   GG+SGFG+PPS+R  R D T  +          + RFPG G  LG 
Sbjct:    1 MAPNELAEWYWNVPRLSRYWFTGSVVLPLLGRIGLLSPYSMILVWEKLAYSFHIWRPITALLYYPISPQTGFHYLINLYFLYSYSTALESGQFAGNPAEYAFLLLFCWICLVALGCAVGLYLLMDPMVLAVLYIWCQLNRDTIVQFWFGMQFKAMYLPWVLLAFNMIIQGGGFTELLGILVGHLYFFLAFKYPQDLGGRQLIGAPEFLYRLLPRQRGGVSGFGVPPSNR-RREDGTDGAGDDERRGGWFQNRFPGAGHRLGQ 261
[Close]
BLAST of Derlin vs. TrEMBL
Match: V4B2N8 (Derlin OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_205920 PE=3 SV=1)

HSP 1 Score: 334.339 bits (856), Expect = 5.526e-112
Identity = 161/252 (63.89%), Postives = 193/252 (76.59%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            M+ NDIG+W+RSIP ++KYWFTGS++ PL G+ G   P  M L +  FI KFQ WRP+TA+ YYP+    GFHYLINLYFLYSYSTRLET  F G+PADY+FML FNW+CLVI+GFAT L LLM+PMI+SVLYVWCQLNKD IV FWFGT+FKAMYLPW+L+AFNM+I  GG  +LLGIVVGHLYFFLMFKYPQ+FGGN  +  P F+YK+ PN  GG+ GFG  PSSR  + +          G+G  LG+
Sbjct:    1 MASNDIGDWFRSIPPITKYWFTGSIVLPLAGRIGLFSPMWMILHFQSFIYKFQFWRPLTAVLYYPIAGPKGFHYLINLYFLYSYSTRLETGIFDGRPADYIFMLFFNWICLVILGFATDLMLLMDPMILSVLYVWCQLNKDQIVSFWFGTRFKAMYLPWVLLAFNMVIGQGGLQELLGIVVGHLYFFLMFKYPQDFGGNRMINVPSFLYKYFPNRRGGMGGFGQAPSSRRNQDNNRGGGGRHDWGQGNQLGN 252
[Close]
BLAST of Derlin vs. Ensembl Cavefish
Match: derl1 (derlin 1 [Source:NCBI gene;Acc:103028975])

HSP 1 Score: 285.419 bits (729), Expect = 4.613e-96
Identity = 132/228 (57.89%), Postives = 172/228 (75.44%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAA 776
            +DIG+W++S+PF+++YWF GS+  PL GK G + P  + L    F  KFQIWRPIT+  Y+PV P TGF YL+NLYFLY YS+RLET  F G+PADY+FML+FNWLC+VI G    + LLM P+I+SVLYVW QLN++ +V FWFGT+FKA YLPW+++ FN II G    +L+G +VGH YFFLMFKYP + GG  +L TPQF+Y++ PN  GG+SGFG+PP+ R  
Sbjct:    2 SDIGDWFKSVPFITRYWFAGSIAVPLIGKLGLISPVFLVLWPEAFFHKFQIWRPITSTLYFPVGPGTGFLYLVNLYFLYQYSSRLETGAFDGRPADYIFMLLFNWLCIVITGLMMDMQLLMIPLIMSVLYVWAQLNRETVVSFWFGTRFKACYLPWVILGFNYIIGGSVVNELIGNLVGHFYFFLMFKYPMDLGGRSFLSTPQFLYRWFPNRRGGVSGFGVPPTRRQV 229
[Close]
BLAST of Derlin vs. Ensembl Cavefish
Match: derl1 (derlin 1 [Source:NCBI gene;Acc:103028975])

HSP 1 Score: 226.098 bits (575), Expect = 2.795e-73
Identity = 111/228 (48.68%), Postives = 145/228 (63.60%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAA 776
            +DIG+W++S+PF+++YWF GS+  PL GK G + P  + L    F  KFQIWRPIT+  Y+PV P TGF YL+NLYFLY YS+RLET  F G+PADY+FML+FNWLC+VI G    + LLM P+I+SVLYVW QLN++ +V FWFGT+FKA YLPW+++ FN II G                                      Y++ PN  GG+SGFG+PP+ R  
Sbjct:    2 SDIGDWFKSVPFITRYWFAGSIAVPLIGKLGLISPVFLVLWPEAFFHKFQIWRPITSTLYFPVGPGTGFLYLVNLYFLYQYSSRLETGAFDGRPADYIFMLLFNWLCIVITGLMMDMQLLMIPLIMSVLYVWAQLNRETVVSFWFGTRFKACYLPWVILGFNYIIGGS-------------------------------------YRWFPNRRGGVSGFGVPPTRRQV 192
[Close]
BLAST of Derlin vs. Ensembl Cavefish
Match: derl2 (derlin 2 [Source:NCBI gene;Acc:103043610])

HSP 1 Score: 130.568 bits (327), Expect = 4.971e-36
Identity = 74/209 (35.41%), Postives = 118/209 (56.46%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFM 707
            M+     + Y  IP V++ + T  VL     +   + P+ ++      ++ +Q+WR +T  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F  L + I G    L  L +   I ++YVW + N +V + F+    F+A +LPW+L+ F++++      DLLGI VGH+YFFL   +P + GG  WLRTP F+
Sbjct:    1 MAYQTFQQEYLQIPVVTRTYTTACVLTTAAVQLELITPFQLYFNPDLILKHYQVWRLVTNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGLLMTIFGMFVSLVFLGQAFTIMLVYVWSRRNPNVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHVYFFLEDVFPNQPGGGRWLRTPSFL 205
[Close]
BLAST of Derlin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008257.1 (pep scaffold:Pmarinus_7.0:GL482614:7679:16539:-1 gene:ENSPMAG00000007457.1 transcript:ENSPMAT00000008257.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 294.278 bits (752), Expect = 2.942e-100
Identity = 136/221 (61.54%), Postives = 173/221 (78.28%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGI 755
             DI EW+R IP V++YWF GSVLFPL G+FG LDP T+ L  T    +FQIWRPITA  ++P+TP TGFH+LI+LYFLYSYSTRLET  F G+PADYLF+++FNW+C+ I+G    + LLM P+IISVLYVW QLN+D IV FWFGT FKA YLPW+++ FN I++G    +L+GI VGHLYFFLMFKYPQ+FGG+  + TP  +Y+ LP+  GG++GFG+
Sbjct:    5 TDIAEWFRGIPVVTRYWFAGSVLFPLLGRFGLLDPATLVLDATRLFSRFQIWRPITATLFFPLTPQTGFHFLIHLYFLYSYSTRLETGVFDGRPADYLFLVLFNWICITIVGIIVDMPLLMIPLIISVLYVWAQLNRDQIVTFWFGTTFKACYLPWVIMGFNFILRGSVMNELIGIFVGHLYFFLMFKYPQDFGGHTLISTPSILYRLLPSRRGGIAGFGV 225
[Close]
BLAST of Derlin vs. Ensembl Yeast
Match: DFM1 (Endoplasmic reticulum (ER) localized protein; involved in ER-associated protein degradation (ERAD), ER stress, and homeostasis; interacts with components of ERAD-L and ERAD-C and Cdc48p; derlin-like family member similar to Der1p [Source:SGD;Acc:S000002819])

HSP 1 Score: 54.6842 bits (130), Expect = 5.611e-9
Identity = 52/207 (25.12%), Postives = 89/207 (43.00%), Query Frame = 3 
Query:   93 NDI---GEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPA-----------DYLFMLIFNWLCLVIIGFATPL-------YLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFT-DLLGIVVGHLYFFL 647
            ND+    E++ +IP +++  FT +++  + G+   ++P+    +W    +K QIWR +T+        M     L+ LY +Y  S++LE   F   P            DY + L F   C++ I  AT +        +L    I  + Y W   N +V + F+        Y P I +  + +   G F   L+G   G+LY  L
Sbjct:   18 NDVMGPKEFWLNIPPITRTLFTLAIVMTIVGRLNLINPWYFIYVWNLTFKKVQIWRLLTSCVMLSSRAMPA---LMELYSIYDRSSQLERGHF--GPGLSNRRGPMVTVDYAYYLCF---CILAITTATTIIYGSYYPVVLTSGFISCITYTWSIDNANVQIMFYGLIPVWGKYFPLIQLFISFVFNEGDFVISLIGFTTGYLYTCL 216
[Close]
BLAST of Derlin vs. Ensembl Nematostella
Match: EDO47541 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM47])

HSP 1 Score: 111.694 bits (278), Expect = 3.015e-29
Identity = 62/199 (31.16%), Postives = 107/199 (53.77%), Query Frame = 3 
Query:  111 YRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFM 707
            Y  +P V++ + T  VL  L  +   + P+ ++       +++QIWR +T   ++      GF++  N+ F Y Y   LE  +F G+ AD++ M IF    + ++     L  L +   I ++Y+W + N  V + F+    FKA +LPW+L  F++++      DL+GI VGH+YFFL   +P++ GG   L+TP F+
Sbjct:   10 YMQMPIVTRAYTTACVLTTLAVQLDVITPFQLYFNPELIFQRYQIWRLVTNFLFFGTI---GFNFFFNMIFTYRYCRMLEEGSFRGRTADFVLMFIFGGALMTVLALFVNLVFLGQAFTIMLVYIWSRRNPYVRMNFFGLLTFKAPFLPWVLFGFSLMLGNSVMVDLIGIAVGHVYFFLEDIFPEQPGGFRILKTPGFL 205
[Close]
BLAST of Derlin vs. Ensembl Medaka
Match: derl1 (derlin 1 [Source:NCBI gene;Acc:101174652])

HSP 1 Score: 288.5 bits (737), Expect = 2.712e-97
Identity = 142/251 (56.57%), Postives = 180/251 (71.71%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSR-AARGDATSSSRPRFP-GRGQTLGD 839
            +DIG+W+RSIPF+++ WF  S+  P  GK G +D   + L       +F IWRPITA FY+P+TP TGF YL+NLYFLY YSTRLET  F G+PADY+FML+FNW+C+VI G    + LLM P+I+SVLYVW Q NKD IV FWFGT+FKA YLPW+++AFN II G    +L G +VGHL+FFLMFKYP + GG  +L TP+F+Y+F PN  GG+SGFG PPS R AA+  A   +  R   G+G  LG+
Sbjct:    2 SDIGDWFRSIPFITRSWFAASIAVPFIGKLGLIDFRNLLLFPELVFSRFHIWRPITATFYFPITPNTGFLYLVNLYFLYHYSTRLETGAFDGRPADYVFMLLFNWICIVITGLLMNMQLLMIPLIMSVLYVWAQFNKDTIVSFWFGTRFKAYYLPWVILAFNFIIGGSFMNELTGNLVGHLFFFLMFKYPMDLGGRSFLSTPEFLYRFFPNRRGGVSGFGAPPSRRPAAQDPAGGGAGGRHNWGQGFRLGE 252
[Close]
BLAST of Derlin vs. Ensembl Medaka
Match: derl1 (derlin 1 [Source:NCBI gene;Acc:101174652])

HSP 1 Score: 286.574 bits (732), Expect = 1.423e-96
Identity = 141/251 (56.18%), Postives = 179/251 (71.31%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSR-AARGDATSSSRPRFP-GRGQTLGD 839
            +DIG+W+RSIPF+++ WF  S+  P  GK G +D   + L       +F IWRPITA FY+P+TP TGF YL+NLYFLY YSTRLET  F G+PADY+FML+FNW+C+V+  F     LLM P+I+SVLYVW Q NKD IV FWFGT+FKA YLPW+++AFN II G    +L G +VGHL+FFLMFKYP + GG  +L TP+F+Y+F PN  GG+SGFG PPS R AA+  A   +  R   G+G  LG+
Sbjct:    2 SDIGDWFRSIPFITRSWFAASIAVPFIGKLGLIDFRNLLLFPELVFSRFHIWRPITATFYFPITPNTGFLYLVNLYFLYHYSTRLETGAFDGRPADYVFMLLFNWICIVLTAFHVLFQLLMIPLIMSVLYVWAQFNKDTIVSFWFGTRFKAYYLPWVILAFNFIIGGSFMNELTGNLVGHLFFFLMFKYPMDLGGRSFLSTPEFLYRFFPNRRGGVSGFGAPPSRRPAAQDPAGGGAGGRHNWGQGFRLGE 252
[Close]
BLAST of Derlin vs. Ensembl Medaka
Match: derl2 (derlin 2 [Source:NCBI gene;Acc:101169873])

HSP 1 Score: 129.798 bits (325), Expect = 1.265e-35
Identity = 79/230 (34.35%), Postives = 125/230 (54.35%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITA-LFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSR 770
            M+   + + Y  IP V++ + T  VL     +   + P+ ++      +  +Q+WR IT  LF+ PV    GF++L N+ FLY Y   LE  +F G+ AD++FM +F  L + I G    L  L +   I ++YVW + N +V + F+    F+A +LPW+L+ F++++      DLLGI VGH+YFFL   +P + GG  WLRTP  + K L +T    + +   P  R
Sbjct:    1 MAYQTLQQEYLQIPIVTRAYTTACVLTTAAVQLEIITPFQLYFNPDLILRNYQVWRLITNFLFFGPV----GFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGLLMTIFGTFVNLVFLGQAFTIMLVYVWSRRNPNVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHVYFFLEDVFPNQPGGGRWLRTPSII-KMLFDTPEEDANYNPLPEER 225
[Close]
BLAST of Derlin vs. Planmine SMEST
Match: SMESG000024268.1 (SMESG000024268.1)

HSP 1 Score: 506.908 bits (1304), Expect = 0.000e+0
Identity = 252/252 (100.00%), Postives = 252/252 (100.00%), Query Frame = 3 
Query:   84 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 839
            MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD
Sbjct:    1 MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTLGD 252
[Close]
BLAST of Derlin vs. Planmine SMEST
Match: SMESG000040218.1 (SMESG000040218.1)

HSP 1 Score: 111.694 bits (278), Expect = 5.580e-29
Identity = 68/207 (32.85%), Postives = 107/207 (51.69%), Query Frame = 3 
Query:   93 NDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIEKFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADYLFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGTQFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNIWLRTPQFMYK 713
            N I + Y  IP V++ + T   +  L     F+ P  ++   T     +Q WR IT   Y+      GF++L N+ F+Y Y   LE + F GK AD++ M +F    ++ IG    L  L     I ++YVW + N  + + F+    F A YLPW+L+ F+ ++      D +GI +GHLY+FL   +P++  G   LRTP+F+ K
Sbjct:    2 NHISQEYLQIPPVTRAYTTICAITTLAVHLEFISPLHLYFNPTLIFRNYQFWRLITNFCYFG---QIGFNFLFNMIFIYRYCRMLEENHFRGKEADFIIMFLFGGALMMFIGSFFALIFLGHAFTIMIVYVWSRRNPYIRMNFFGLFNFYAPYLPWVLLGFSFLLNNSVLVDAVGIGIGHLYYFLEDVFPRQTNGFKILRTPRFLKK 205
The following BLAST results are available for this feature:
BLAST of Derlin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DERL11.614e-10157.83derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454][more]
DERL18.003e-8853.01derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454][more]
DERL11.177e-5355.33derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454][more]
DERL11.177e-5355.33derlin 1 [Source:HGNC Symbol;Acc:HGNC:28454][more]
DERL28.950e-3136.00derlin 2 [Source:HGNC Symbol;Acc:HGNC:17943][more]
back to top
BLAST of Derlin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
cup-21.724e-8250.20Derlin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q93561][more]
cup-21.724e-8250.20Derlin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q93561][more]
R151.62.111e-2228.29Derlin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21997][more]
back to top
BLAST of Derlin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Der-11.955e-6744.13gene:FBgn0267972 transcript:FBtr0077813[more]
Der-11.955e-6744.13gene:FBgn0267972 transcript:FBtr0334758[more]
Der-21.886e-2630.05gene:FBgn0038438 transcript:FBtr0083307[more]
back to top
BLAST of Derlin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
derl11.078e-9760.18derlin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2793][more]
derl22.063e-3533.91derlin 2 [Source:ZFIN;Acc:ZDB-GENE-050522-90][more]
derl31.150e-3133.65derlin 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1324][more]
derl31.332e-3133.82derlin 3 [Source:ZFIN;Acc:ZDB-GENE-040426-1324][more]
back to top
BLAST of Derlin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
derl12.574e-9356.40lipoxygenase homology domain-containing protein 1-... [more]
derl11.892e-8955.73lipoxygenase homology domain-containing protein 1-... [more]
orc66.022e-3235.44origin recognition complex subunit 6 [Source:Xenba... [more]
back to top
BLAST of Derlin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Derl17.231e-10057.03Der1-like domain family, member 1 [Source:MGI Symb... [more]
Derl26.275e-3136.00Der1-like domain family, member 2 [Source:MGI Symb... [more]
Derl28.413e-3136.00Der1-like domain family, member 2 [Source:MGI Symb... [more]
Derl36.301e-2929.44Der1-like domain family, member 3 [Source:MGI Symb... [more]
Derl31.071e-2728.97Der1-like domain family, member 3 [Source:MGI Symb... [more]
back to top
BLAST of Derlin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9BUN8|DERL1_HUMAN7.749e-10157.83Derlin-1 OS=Homo sapiens OX=9606 GN=DERL1 PE=1 SV=... [more]
sp|Q5R9W3|DERL1_PONAB8.548e-10157.83Derlin-1 OS=Pongo abelii OX=9601 GN=DERL1 PE=2 SV=... [more]
sp|Q71SS4|DERL1_BOVIN3.132e-10057.83Derlin-1 OS=Bos taurus OX=9913 GN=DERL1 PE=2 SV=1[more]
sp|Q99J56|DERL1_MOUSE5.058e-9957.03Derlin-1 OS=Mus musculus OX=10090 GN=Derl1 PE=1 SV... [more]
sp|Q93561|DERL1_CAEEL2.193e-8150.20Derlin-1 OS=Caenorhabditis elegans OX=6239 GN=cup-... [more]
back to top
BLAST of Derlin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
R7V7G01.017e-11867.72Derlin OS=Capitella teleta OX=283909 GN=CAPTEDRAFT... [more]
C3YFB11.497e-11565.20Derlin OS=Branchiostoma floridae OX=7739 GN=BRAFLD... [more]
W4YQI81.814e-11364.29Derlin OS=Strongylocentrotus purpuratus OX=7668 PE... [more]
A0A267FI241.878e-11360.69Derlin OS=Macrostomum lignano OX=282301 GN=BOX15_M... [more]
V4B2N85.526e-11263.89Derlin OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_... [more]
back to top
BLAST of Derlin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
derl14.613e-9657.89derlin 1 [Source:NCBI gene;Acc:103028975][more]
derl12.795e-7348.68derlin 1 [Source:NCBI gene;Acc:103028975][more]
derl24.971e-3635.41derlin 2 [Source:NCBI gene;Acc:103043610][more]
back to top
BLAST of Derlin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000008257.12.942e-10061.54pep scaffold:Pmarinus_7.0:GL482614:7679:16539:-1 g... [more]
back to top
BLAST of Derlin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DFM15.611e-925.12Endoplasmic reticulum (ER) localized protein; invo... [more]
back to top
BLAST of Derlin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO475413.015e-2931.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Derlin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
derl12.712e-9756.57derlin 1 [Source:NCBI gene;Acc:101174652][more]
derl11.423e-9656.18derlin 1 [Source:NCBI gene;Acc:101174652][more]
derl21.265e-3534.35derlin 2 [Source:NCBI gene;Acc:101169873][more]
back to top
BLAST of Derlin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000024268.10.000e+0100.00SMESG000024268.1[more]
SMESG000040218.15.580e-2932.85SMESG000040218.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011670 ID=SMED30011670|Name=Derlin|organism=Schmidtea mediterranea sexual|type=transcript|length=959bp
GTTTAAAATTTACTATATATTTATAGAATAGTAAAATTCTTTTGTTAGTT
TATTTTTACTATTTGCTTTTCTTTTAAAATCTAATGTCTGGTAATGATAT
TGGAGAATGGTATCGATCTATACCATTTGTTTCCAAATATTGGTTCACTG
GTAGTGTTCTATTTCCCCTTTTTGGTAAATTTGGATTTCTTGATCCTTAC
ACAATGTTTTTGATATGGACACCTTTTATTGAGAAATTTCAAATATGGAG
ACCAATTACCGCACTGTTTTATTATCCCGTTACACCTATGACAGGATTTC
ATTACTTGATCAATCTGTATTTTCTATATTCATATTCAACCCGATTAGAA
ACAAGTACGTTTATCGGAAAACCAGCTGATTACCTGTTTATGTTAATTTT
CAACTGGCTTTGCTTAGTTATTATTGGATTTGCTACACCATTATATTTAC
TGATGGAACCGATGATCATCAGTGTTCTATATGTTTGGTGCCAATTGAAT
AAGGATGTCATCGTTCAATTCTGGTTCGGCACCCAATTCAAAGCGATGTA
TTTGCCCTGGATTTTGGTAGCTTTTAATATGATAATTCAAGGAGGTGGAT
TTACTGATTTGCTGGGAATTGTTGTTGGGCATTTGTATTTCTTCTTGATG
TTTAAATATCCACAAGAATTCGGAGGAAATATTTGGCTAAGAACTCCACA
ATTTATGTACAAATTTCTACCCAACACAATTGGAGGTCTGTCGGGCTTTG
GCATTCCGCCGTCGTCCCGAGCTGCCAGAGGAGACGCGACCAGCTCTAGT
CGCCCGAGGTTCCCAGGAAGGGGCCAAACATTGGGCGACTGAGAGTTGGT
TTCCATGGTTTCGATGATAAATTGGTCATTTTAATTTAAATAAATTATAA
ATTCATTGTTTTATTTATTGAACTTATTTTTTCCTTTATATTTGTCGGGA
AATATCAAA
back to top

protein sequence of SMED30011670-orf-1

>SMED30011670-orf-1 ID=SMED30011670-orf-1|Name=SMED30011670-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=253bp
MSGNDIGEWYRSIPFVSKYWFTGSVLFPLFGKFGFLDPYTMFLIWTPFIE
KFQIWRPITALFYYPVTPMTGFHYLINLYFLYSYSTRLETSTFIGKPADY
LFMLIFNWLCLVIIGFATPLYLLMEPMIISVLYVWCQLNKDVIVQFWFGT
QFKAMYLPWILVAFNMIIQGGGFTDLLGIVVGHLYFFLMFKYPQEFGGNI
WLRTPQFMYKFLPNTIGGLSGFGIPPSSRAARGDATSSSRPRFPGRGQTL
GD*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000103central nervous system
PLANA:0000142posterior region of the whole animal
PLANA:0000208testis
PLANA:0000231vitelline gland
Vocabulary: INTERPRO
TermDefinition
IPR007599DER1
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007599DerlinPFAMPF04511DER1coord: 13..206
e-value: 1.2E-62
score: 211.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 229..252
NoneNo IPR availablePANTHERPTHR11009DER1-LIKE PROTEIN, DERLINcoord: 7..251
NoneNo IPR availablePANTHERPTHR11009:SF1DERLIN-1coord: 7..251
NoneNo IPR availableSUPERFAMILYSSF144091Rhomboid-likecoord: 11..194
NoneNo IPR availableTMHMMTMhelixcoord: 21..43
NoneNo IPR availableTMHMMTMhelixcoord: 58..80
NoneNo IPR availableTMHMMTMhelixcoord: 159..181
NoneNo IPR availableTMHMMTMhelixcoord: 101..123