Actin-related protein 2/3 complex subunit 4

Overview


Name	Actin-related protein 2/3 complex subunit 4
Smed ID	SMED30011617
Length (bp)	818

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Actin-related protein 2/3 complex subunit 4 (SMED30011617) t-SNE clustered cells

Violin plots show distribution of expression levels for Actin-related protein 2/3 complex subunit 4 (SMED30011617) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Actin-related protein 2/3 complex subunit 4 (SMED30011617) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Actin-related protein 2/3 complex subunit 4 (SMED30011617) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30011617

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30011617	h1SMcG0001944	Contig1665	GPL15192	PMID:23079596 Forsthoefel et al., 2012
epidermis	SMED30011617	h1SMcG0001944	Contig1665	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30011617	h1SMcG0001944	Contig1665	GPL15192	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30011617	h1SMcG0001944	dd_Smed_v4_977_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30011617	h1SMcG0001944	dd_Smed_v4_977_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30011617	h1SMcG0001944	dd_Smed_v4_977_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30011617	h1SMcG0001944	dd_Smed_v4_977_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011617	h1SMcG0001944	Contig1665	GPL15192	PMID:29674431 Fincher et al., 2018
Category 4 cell	SMED30011617	h1SMcG0001944	dd_Smed_v4_977_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
Match: ARPC4 (actin related protein 2/3 complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:707])

HSP 1 Score: 276.944 bits (707), Expect = 1.701e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
Match: ARPC4 (actin related protein 2/3 complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:707])

HSP 1 Score: 275.789 bits (704), Expect = 7.985e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:   23 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 187

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
Match: ARPC4-TTLL3 (ARPC4-TTLL3 readthrough [Source:HGNC Symbol;Acc:HGNC:38830])

HSP 1 Score: 275.018 bits (702), Expect = 1.612e-93
Identity = 131/163 (80.37%), Postives = 148/163 (90.80%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLK 596
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLK 166

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
Match: ARPC4-TTLL3 (ARPC4-TTLL3 readthrough [Source:HGNC Symbol;Acc:HGNC:38830])

HSP 1 Score: 201.83 bits (512), Expect = 6.022e-65
Identity = 105/163 (64.42%), Postives = 119/163 (73.01%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLK 596
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++K                                QGYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVK--------------------------------QGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLK 134

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
Match: ARPC4 (actin related protein 2/3 complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:707])

HSP 1 Score: 180.644 bits (457), Expect = 2.325e-57
Identity = 85/107 (79.44%), Postives = 97/107 (90.65%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQ 428
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVE 110

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Celegans
Match: arx-6 (Probable actin-related protein 2/3 complex subunit 4 [Source:UniProtKB/Swiss-Prot;Acc:P58798])

HSP 1 Score: 257.684 bits (657), Expect = 2.834e-87
Identity = 120/166 (72.29%), Postives = 146/166 (87.95%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
             L+PYL AVRH+L+AALCL  F SQVVERHNKPEVEV++SKELL+T +V++RN++E+VLIE S+NSVRISI+IKQSDEIEK+LCHKFTRFM  RA+ F +LRRKP+ GYDISFLIT  HTE M KHKLVDF++ FM++IDKEISEM+L++NARAR  AEEFLK F+
Sbjct:    4 TLQPYLEAVRHTLQAALCLEQFSSQVVERHNKPEVEVQTSKELLMTPVVVARNKQERVLIEPSVNSVRISIAIKQSDEIEKILCHKFTRFMCQRADNFFVLRRKPLPGYDISFLITASHTEAMFKHKLVDFLLHFMQEIDKEISEMKLSLNARARVSAEEFLKRFN 169

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Fly
Match: Arpc4 (gene:FBgn0284255 transcript:FBtr0079200)

HSP 1 Score: 279.256 bits (713), Expect = 8.655e-96
Identity = 131/165 (79.39%), Postives = 150/165 (90.91%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             LKPYL AVRHSL AA+CL +F SQVVERHNKPEVE+ SSKEL+LT +V+SRNE+EKVLIE SINSVR+SI++KQ+DEIE++LCHKFTRFMM RAE FVILRRKP++GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+LA+NARAR CAEEFLK F
Sbjct:    4 TLKPYLTAVRHSLTAAMCLQDFPSQVVERHNKPEVEICSSKELVLTPVVVSRNEREKVLIEPSINSVRVSIAVKQADEIERILCHKFTRFMMRRAESFVILRRKPIEGYDISFLITNFHTEQMYKHKLVDFVISFMEEIDKEISEMKLAVNARARTCAEEFLKRF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Zebrafish
Match: arpc4 (actin related protein 2/3 complex, subunit 4 [Source:ZFIN;Acc:ZDB-GENE-010724-9])

HSP 1 Score: 275.789 bits (704), Expect = 2.959e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Zebrafish
Match: arpc4l (actin related protein 2/3 complex, subunit 4, like [Source:ZFIN;Acc:ZDB-GENE-040808-18])

HSP 1 Score: 275.789 bits (704), Expect = 2.959e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Zebrafish
Match: arpc4 (actin related protein 2/3 complex, subunit 4 [Source:ZFIN;Acc:ZDB-GENE-010724-9])

HSP 1 Score: 275.404 bits (703), Expect = 9.975e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:   29 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 193

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Xenopus
Match: acox2 (acyl-CoA oxidase 2, branched chain [Source:NCBI gene;Acc:548740])

HSP 1 Score: 72.4034 bits (176), Expect = 9.721e-14
Identity = 34/43 (79.07%), Postives = 39/43 (90.70%), Query Frame = 3

Query:  468 EQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLK 596
            EQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK
Sbjct:    1 EQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLK 43

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Mouse
Match: Arpc4 (actin related protein 2/3 complex, subunit 4 [Source:MGI Symbol;Acc:MGI:1915339])

HSP 1 Score: 276.944 bits (707), Expect = 1.168e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Mouse
Match: Arpc4 (actin related protein 2/3 complex, subunit 4 [Source:MGI Symbol;Acc:MGI:1915339])

HSP 1 Score: 154.451 bits (389), Expect = 1.254e-47
Identity = 73/90 (81.11%), Postives = 81/90 (90.00%), Query Frame = 3

Query:  333 SDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
            +DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    2 ADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 91

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Mouse
Match: Arpc4 (actin related protein 2/3 complex, subunit 4 [Source:MGI Symbol;Acc:MGI:1915339])

HSP 1 Score: 132.88 bits (333), Expect = 2.289e-39
Identity = 63/77 (81.82%), Postives = 69/77 (89.61%), Query Frame = 3

Query:  372 RFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
            RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    2 RFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 78

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Mouse
Match: Arpc4 (actin related protein 2/3 complex, subunit 4 [Source:MGI Symbol;Acc:MGI:1915339])

HSP 1 Score: 132.88 bits (333), Expect = 2.289e-39
Identity = 63/77 (81.82%), Postives = 69/77 (89.61%), Query Frame = 3

Query:  372 RFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
            RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    2 RFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 78

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q641G7|ARPC4_XENLA (Actin-related protein 2/3 complex subunit 4 OS=Xenopus laevis OX=8355 GN=arpc4 PE=1 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 8.078e-94
Identity = 133/165 (80.61%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
Match: sp|P59999|ARPC4_MOUSE (Actin-related protein 2/3 complex subunit 4 OS=Mus musculus OX=10090 GN=Arpc4 PE=1 SV=3)

HSP 1 Score: 276.944 bits (707), Expect = 8.167e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
Match: sp|P59998|ARPC4_HUMAN (Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3)

HSP 1 Score: 276.944 bits (707), Expect = 8.167e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q148J6|ARPC4_BOVIN (Actin-related protein 2/3 complex subunit 4 OS=Bos taurus OX=9913 GN=ARPC4 PE=1 SV=3)

HSP 1 Score: 276.944 bits (707), Expect = 8.167e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL+AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  + ISRNEKEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
Match: sp|P58798|ARPC4_CAEEL (Probable actin-related protein 2/3 complex subunit 4 OS=Caenorhabditis elegans OX=6239 GN=arx-6 PE=3 SV=1)

HSP 1 Score: 257.684 bits (657), Expect = 3.605e-86
Identity = 120/166 (72.29%), Postives = 146/166 (87.95%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
             L+PYL AVRH+L+AALCL  F SQVVERHNKPEVEV++SKELL+T +V++RN++E+VLIE S+NSVRISI+IKQSDEIEK+LCHKFTRFM  RA+ F +LRRKP+ GYDISFLIT  HTE M KHKLVDF++ FM++IDKEISEM+L++NARAR  AEEFLK F+
Sbjct:    4 TLQPYLEAVRHTLQAALCLEQFSSQVVERHNKPEVEVQTSKELLMTPVVVARNKQERVLIEPSVNSVRISIAIKQSDEIEKILCHKFTRFMCQRADNFFVLRRKPLPGYDISFLITASHTEAMFKHKLVDFLLHFMQEIDKEISEMKLSLNARARVSAEEFLKRFN 169

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
Match: A0A075ACN9 (Uncharacterized protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=T265_12580 PE=4 SV=1)

HSP 1 Score: 290.426 bits (742), Expect = 1.103e-96
Identity = 139/166 (83.73%), Postives = 154/166 (92.77%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
            ALKPYL AVRH+L AALC+ NF SQVVERHNKPE+EVK+SKELLL  +VISRNEKE+VLIEGSINSVR+SISIKQSDEIE+LLC KFTRFMMMRAE+FVILRRKPV GYDISFLITN HTEQM K K+VDF+I FM++IDKEISEMRLA+N+RARQCAEEFLKAFD
Sbjct:    1 ALKPYLTAVRHTLHAALCVQNFPSQVVERHNKPEIEVKTSKELLLQPVVISRNEKERVLIEGSINSVRVSISIKQSDEIERLLCRKFTRFMMMRAEDFVILRRKPVPGYDISFLITNFHTEQMSKTKVVDFVITFMDEIDKEISEMRLAVNSRARQCAEEFLKAFD 166

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
Match: A0A5K4FDI4 (Actin-related protein 2/3 complex subunit 4 OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 290.041 bits (741), Expect = 1.749e-96
Identity = 138/167 (82.63%), Postives = 154/167 (92.22%), Query Frame = 3

Query:  105 MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
            MALKPYL AVRH+L AALC+ NF SQVVERHNKPE+EV++SKELLL  ++ISRNEKE+VLIEGSINSVR+SI+IKQSDEIEKLLC KFTRFMM RAE+FVILRRKPV GYDISFLITN HTEQM K KLVDF+I FM++IDKEISEMRLA+N+RARQCAEEFLKAFD
Sbjct:    1 MALKPYLNAVRHTLNAALCVQNFSSQVVERHNKPEIEVRTSKELLLNPVIISRNEKERVLIEGSINSVRVSIAIKQSDEIEKLLCRKFTRFMMTRAEDFVILRRKPVPGYDISFLITNFHTEQMSKAKLVDFVITFMDEIDKEISEMRLAVNSRARQCAEEFLKAFD 167

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
Match: A0A4S2LYN4 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_005370 PE=4 SV=1)

HSP 1 Score: 291.197 bits (744), Expect = 4.122e-96
Identity = 139/167 (83.23%), Postives = 155/167 (92.81%), Query Frame = 3

Query:  105 MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
            +ALKPYL AVRH+L AALC+ NF SQVVERHNKPE+EVK+SKELLL  +VISRNEKE+VLIEGSINSVR+SISIKQSDEIE+LLC KFTRFMMMRAE+FVILRRKPV GYDISFLITN HTEQM K K+VDF+I FM++IDKEISEMRLA+N+RARQCAEEFLKAFD
Sbjct:   61 VALKPYLTAVRHTLHAALCVQNFPSQVVERHNKPEIEVKTSKELLLQPVVISRNEKERVLIEGSINSVRVSISIKQSDEIERLLCRKFTRFMMMRAEDFVILRRKPVPGYDISFLITNFHTEQMSKTKVVDFVITFMDEIDKEISEMRLAVNSRARQCAEEFLKAFD 227

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
Match: G7YPX6 (Actin related protein 2/3 complex subunit 4 OS=Clonorchis sinensis OX=79923 GN=CLF_106420 PE=4 SV=1)

HSP 1 Score: 293.508 bits (750), Expect = 5.870e-96
Identity = 139/167 (83.23%), Postives = 154/167 (92.22%), Query Frame = 3

Query:  105 MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
             ALKPYL AVRH+L AALC+ NF SQVVERHNKPE+EVK+SKELLL  +VISRNEKE+VLIEGSINSVR+SISIKQSDEIE+LLC KFTRFMMMRAE+FVILRRKPV GYDISFLITN HTEQM K K+VDF+I FM++IDKEISEMRLA+N+RARQCAEEFLKAFD
Sbjct:  133 FALKPYLTAVRHTLHAALCVQNFPSQVVERHNKPEIEVKTSKELLLQPVVISRNEKERVLIEGSINSVRVSISIKQSDEIERLLCRKFTRFMMMRAEDFVILRRKPVPGYDISFLITNFHTEQMSKAKVVDFVITFMDEIDKEISEMRLAVNSRARQCAEEFLKAFD 299

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
Match: G4V7X7 (Actin-related protein 2/3 complex subunit 4 OS=Schistosoma mansoni OX=6183 GN=Smp_160770.1 PE=3 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 6.603e-96
Identity = 137/166 (82.53%), Postives = 153/166 (92.17%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
            ALKPYL AVRH+L AALC+ NF SQVVERHNKPE+EV++SKELLL  ++ISRNEKE+VLIEGSINSVR+SI+IKQSDEIEKLLC KFTRFMM RAE+FVILRRKPV GYDISFLITN HTEQM K KLVDF+I FM++IDKEISEMRLA+N+RARQCAEEFLKAFD
Sbjct:    5 ALKPYLNAVRHTLNAALCVQNFSSQVVERHNKPEIEVRTSKELLLNPVIISRNEKERVLIEGSINSVRVSIAIKQSDEIEKLLCRKFTRFMMTRAEDFVILRRKPVPGYDISFLITNFHTEQMSKAKLVDFVITFMDEIDKEISEMRLAVNSRARQCAEEFLKAFD 170

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
Match: arpc4l (actin-related protein 2/3 complex subunit 4-like [Source:NCBI gene;Acc:103043660])

HSP 1 Score: 276.944 bits (707), Expect = 7.449e-95
Identity = 133/165 (80.61%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+LA+NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLAVNARARIVAEEFLKNF 168

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
Match: arpc4 (actin-related protein 2/3 complex subunit 4 [Source:NCBI gene;Acc:103038900])

HSP 1 Score: 275.789 bits (704), Expect = 2.508e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
Match: arpc4 (actin-related protein 2/3 complex subunit 4 [Source:NCBI gene;Acc:103038900])

HSP 1 Score: 275.404 bits (703), Expect = 8.747e-94
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:   30 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 194

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
Match: arpc4l (actin-related protein 2/3 complex subunit 4-like [Source:NCBI gene;Acc:103043660])

HSP 1 Score: 273.863 bits (699), Expect = 7.227e-93
Identity = 132/163 (80.98%), Postives = 148/163 (90.80%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLK 596
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+LA+NARAR  AEEFLK
Sbjct:    6 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLAVNARARIVAEEFLK 168

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
Match: arpc4l (actin-related protein 2/3 complex subunit 4-like [Source:NCBI gene;Acc:103043660])

HSP 1 Score: 273.863 bits (699), Expect = 7.451e-93
Identity = 132/163 (80.98%), Postives = 148/163 (90.80%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLK 596
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+LA+NARAR  AEEFLK
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLAVNARARIVAEEFLK 166

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009646.1 (pep scaffold:Pmarinus_7.0:GL477881:502174:523288:1 gene:ENSPMAG00000008716.1 transcript:ENSPMAT00000009646.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 177.563 bits (449), Expect = 3.323e-57
Identity = 85/107 (79.44%), Postives = 95/107 (88.79%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQ 428
             L+PYL AVR +L+A LCL NF SQVVERHNKPEVEV+S KELLL  ++ISRNEKEKVLIEGSINSVRISIS+KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+
Sbjct:    4 TLRPYLNAVRATLQATLCLENFSSQVVERHNKPEVEVRSGKELLLQPVMISRNEKEKVLIEGSINSVRISISVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVE 110

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Yeast
Match: ARC19 (Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches; mutation is functionally complemented by human ARPC4 [Source:SGD;Acc:S000001496])

HSP 1 Score: 224.172 bits (570), Expect = 6.855e-75
Identity = 112/166 (67.47%), Postives = 133/166 (80.12%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEV-KSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
            +L+PYL AVR+SLEAAL LSNF SQ VERHN+PEVEV  +S ELLL  + ISRNE E+VLIE S+NSVR+S+ +KQ+DEIE++L HKFTRF+  RAE F ILRR P+ GY ISFLITN HTE M   KLVDFII FMED+DKEISE++L +NARAR  AE +L  F
Sbjct:    4 SLRPYLTAVRYSLEAALTLSNFSSQEVERHNRPEVEVPNTSAELLLQPMHISRNENEQVLIEPSVNSVRMSLMVKQADEIEQILVHKFTRFLEQRAEAFYILRRVPIPGYSISFLITNKHTESMKTGKLVDFIIEFMEDVDKEISEIKLFLNARARFVAEAYLDEF 169

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Nematostella
Match: EDO46006 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRG4])

HSP 1 Score: 279.641 bits (714), Expect = 2.985e-96
Identity = 133/165 (80.61%), Postives = 150/165 (90.91%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L AA+CL NFDSQVVERHNKPEVEV+SSKELLLT +VISRNEKEKVLIEGSINS+RISI++KQ+DEIEK+LC KF RFMMMRAE F +LRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR CAEEFLK F
Sbjct:    4 TLRPYLNAVRSTLTAAMCLENFDSQVVERHNKPEVEVRSSKELLLTPLVISRNEKEKVLIEGSINSMRISIAVKQADEIEKILCKKFMRFMMMRAENFFVLRRKPVEGYDISFLITNFHTEQMFKHKLVDFVIQFMEEIDKEISEMKLSLNARARICAEEFLKNF 168

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BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Medaka
Match: arpc4 (actin-related protein 2/3 complex subunit 4 [Source:NCBI gene;Acc:101159909])

HSP 1 Score: 274.248 bits (700), Expect = 1.056e-93
Identity = 131/165 (79.39%), Postives = 148/165 (89.70%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKV IEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:    4 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVFIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Medaka
Match: arpc4 (actin-related protein 2/3 complex subunit 4 [Source:NCBI gene;Acc:101157122])

HSP 1 Score: 276.944 bits (707), Expect = 2.320e-93
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:   96 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 260

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Medaka
Match: arpc4 (actin-related protein 2/3 complex subunit 4 [Source:NCBI gene;Acc:101157122])

HSP 1 Score: 276.559 bits (706), Expect = 5.121e-93
Identity = 132/165 (80.00%), Postives = 149/165 (90.30%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKVLIEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:  118 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 282

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Medaka
Match: arpc4 (actin-related protein 2/3 complex subunit 4 [Source:NCBI gene;Acc:101159909])

HSP 1 Score: 272.707 bits (696), Expect = 6.921e-93
Identity = 131/165 (79.39%), Postives = 148/165 (89.70%), Query Frame = 3

Query:  108 ALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAF 602
             L+PYL AVR +L+AALCL NF SQVVERHNKPEVEV+SSKELLL  +VISRN+KEKV IEGSINSVR+SI++KQ+DEIEK+LCHKF RFMMMRAE F ILRRKPV+GYDISFLITN HTEQM KHKLVDF+I FME+IDKEISEM+L++NARAR  AEEFLK F
Sbjct:   20 TLRPYLNAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVVISRNDKEKVFIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 184

[Close]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Planmine SMEST
Match: SMESG000003841.1 (SMESG000003841.1)

HSP 1 Score: 337.806 bits (865), Expect = 5.523e-119
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 3

Query:  105 MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 605
            MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD
Sbjct:    1 MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIVISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFVILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLAMNARARQCAEEFLKAFD 167

The following BLAST results are available for this feature:

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Celegans
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Fly
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Zebrafish
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Xenopus
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Mouse
BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Sea Lamprey
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Yeast
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Nematostella
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Medaka
BLAST of Actin-related protein 2/3 complex subunit 4 vs. Planmine SMEST

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARPC4	1.701e-94	80.00	actin related protein 2/3 complex subunit 4 [Sourc...	[more]
ARPC4	7.985e-94	80.00	actin related protein 2/3 complex subunit 4 [Sourc...	[more]
ARPC4-TTLL3	1.612e-93	80.37	ARPC4-TTLL3 readthrough [Source:HGNC Symbol;Acc:HG...	[more]
ARPC4-TTLL3	6.022e-65	64.42	ARPC4-TTLL3 readthrough [Source:HGNC Symbol;Acc:HG...	[more]
ARPC4	2.325e-57	79.44	actin related protein 2/3 complex subunit 4 [Sourc...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
arx-6	2.834e-87	72.29	Probable actin-related protein 2/3 complex subunit...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Arpc4	8.655e-96	79.39	gene:FBgn0284255 transcript:FBtr0079200	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arpc4	2.959e-94	80.00	actin related protein 2/3 complex, subunit 4 [Sour...	[more]
arpc4	2.959e-94	80.00	actin related protein 2/3 complex, subunit 4 [Sour...	[more]
arpc4l	2.959e-94	80.00	actin related protein 2/3 complex, subunit 4, like...	[more]
arpc4l	2.959e-94	80.00	actin related protein 2/3 complex, subunit 4, like...	[more]
arpc4	9.975e-94	80.00	actin related protein 2/3 complex, subunit 4 [Sour...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
acox2	9.721e-14	79.07	acyl-CoA oxidase 2, branched chain [Source:NCBI ge...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Arpc4	1.168e-94	80.00	actin related protein 2/3 complex, subunit 4 [Sour...	[more]
Arpc4	1.254e-47	81.11	actin related protein 2/3 complex, subunit 4 [Sour...	[more]
Arpc4	2.289e-39	81.82	actin related protein 2/3 complex, subunit 4 [Sour...	[more]
Arpc4	2.289e-39	81.82	actin related protein 2/3 complex, subunit 4 [Sour...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q641G7\|ARPC4_XENLA	8.078e-94	80.61	Actin-related protein 2/3 complex subunit 4 OS=Xen...	[more]
sp\|P59999\|ARPC4_MOUSE	8.167e-94	80.00	Actin-related protein 2/3 complex subunit 4 OS=Mus...	[more]
sp\|P59998\|ARPC4_HUMAN	8.167e-94	80.00	Actin-related protein 2/3 complex subunit 4 OS=Hom...	[more]
sp\|Q148J6\|ARPC4_BOVIN	8.167e-94	80.00	Actin-related protein 2/3 complex subunit 4 OS=Bos...	[more]
sp\|P58798\|ARPC4_CAEEL	3.605e-86	72.29	Probable actin-related protein 2/3 complex subunit...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A075ACN9	1.103e-96	83.73	Uncharacterized protein (Fragment) OS=Opisthorchis...	[more]
A0A5K4FDI4	1.749e-96	82.63	Actin-related protein 2/3 complex subunit 4 OS=Sch...	[more]
A0A4S2LYN4	4.122e-96	83.23	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
G7YPX6	5.870e-96	83.23	Actin related protein 2/3 complex subunit 4 OS=Clo...	[more]
G4V7X7	6.603e-96	82.53	Actin-related protein 2/3 complex subunit 4 OS=Sch...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arpc4l	7.449e-95	80.61	actin-related protein 2/3 complex subunit 4-like [...	[more]
arpc4	2.508e-94	80.00	actin-related protein 2/3 complex subunit 4 [Sourc...	[more]
arpc4	8.747e-94	80.00	actin-related protein 2/3 complex subunit 4 [Sourc...	[more]
arpc4l	7.227e-93	80.98	actin-related protein 2/3 complex subunit 4-like [...	[more]
arpc4l	7.451e-93	80.98	actin-related protein 2/3 complex subunit 4-like [...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000009646.1	3.323e-57	79.44	pep scaffold:Pmarinus_7.0:GL477881:502174:523288:1...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ARC19	6.855e-75	67.47	Subunit of the ARP2/3 complex; ARP2/3 is required ...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO46006	2.985e-96	80.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
arpc4	1.056e-93	79.39	actin-related protein 2/3 complex subunit 4 [Sourc...	[more]
arpc4	2.320e-93	80.00	actin-related protein 2/3 complex subunit 4 [Sourc...	[more]
arpc4	5.121e-93	80.00	actin-related protein 2/3 complex subunit 4 [Sourc...	[more]
arpc4	6.921e-93	79.39	actin-related protein 2/3 complex subunit 4 [Sourc...	[more]

BLAST of Actin-related protein 2/3 complex subunit 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000003841.1	5.523e-119	100.00	SMESG000003841.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30011617 ID=SMED30011617|Name=Actin-related protein 2/3 complex subunit 4|organism=Schmidtea mediterranea sexual|type=transcript|length=818bp
CCGGAATTTGCTGTCTTGTTTTTCTACATAAAAACAATTTATTACTAAAG
TTGAAATTTAAACAATTTAAATTGAAAAATTAAAGGAAATTTTTTAATTT
TAAAATGGCTTTGAAACCATATTTAGCTGCTGTTCGGCATTCATTAGAAG
CTGCATTATGTCTTAGTAATTTTGATTCACAAGTTGTGGAGCGTCACAAC
AAGCCTGAAGTTGAAGTAAAATCATCGAAAGAACTGTTGCTTACCTCAAT
AGTTATAAGCAGAAATGAGAAAGAAAAAGTTCTTATTGAGGGCTCTATTA
ATTCGGTTCGTATTAGCATTTCCATTAAACAATCTGATGAAATCGAGAAA
TTGTTATGTCATAAATTTACTAGATTTATGATGATGAGGGCAGAAGAATT
TGTTATTTTACGTCGAAAACCTGTACAAGGATATGACATTAGTTTTCTAA
TAACAAATGTACATACTGAGCAAATGCTCAAACACAAATTAGTTGATTTT
ATCATTGGATTCATGGAAGATATTGATAAAGAAATCTCAGAAATGAGACT
TGCTATGAATGCTCGAGCTCGTCAATGCGCTGAAGAATTCCTGAAAGCAT
TCGATTAGTAATACTAAAAGTTATTCAAAATACTTTTTTCTATAATAAAT
TTGATTGACTTGTTTTATATTACGAGTTCCTTGACTTGCTATTTTGACTT
GCTAATAATTGTTGATGGACCTCTTGGCATTTGCTATCAATACAGTTGAG
CTAGTCCAATTAATTATTTTATTTAACTTGTGATTAAATAAACTGTTAAT
TTTAAAAAAAAAGATCGG

protein sequence of SMED30011617-orf-1

>SMED30011617-orf-1 ID=SMED30011617-orf-1|Name=SMED30011617-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=168bp
MALKPYLAAVRHSLEAALCLSNFDSQVVERHNKPEVEVKSSKELLLTSIV
ISRNEKEKVLIEGSINSVRISISIKQSDEIEKLLCHKFTRFMMMRAEEFV
ILRRKPVQGYDISFLITNVHTEQMLKHKLVDFIIGFMEDIDKEISEMRLA
MNARARQCAEEFLKAFD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003779	actin binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0035861	site of double-strand break
GO:0042995	cell projection
GO:0005885	Arp2/3 protein complex
GO:0015629	actin cytoskeleton

Vocabulary: **biological process**
Term	Definition
GO:0030833	regulation of actin filament polymerization
GO:0034314	Arp2/3 complex-mediated actin nucleation
GO:0030041	actin filament polymerization

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000018	Category 4 cell
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0002032	epidermal cell
PLANA:0002056	medial muscle cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR034666	ARPC2/4
IPR008384	ARPC4

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR008384	Actin-related protein 2/3 complex subunit 4	PIRSF	PIRSF039100	ARPC4	coord: 1..167 e-value: 1.1E-82 score: 273.5
IPR008384	Actin-related protein 2/3 complex subunit 4	PFAM	PF05856	ARPC4	coord: 2..164 e-value: 3.6E-79 score: 264.2
IPR008384	Actin-related protein 2/3 complex subunit 4	PANTHER	PTHR22629	ARP2/3 COMPLEX 20 KD SUBUNIT	coord: 2..166
IPR034666	Arp2/3 complex subunit 2/4	GENE3D	G3DSA:3.30.1460.20		coord: 1..166 e-value: 3.4E-82 score: 275.9
IPR034666	Arp2/3 complex subunit 2/4	SUPERFAMILY	SSF69645	Arp2/3 complex subunits	coord: 3..166