AP2-associated protein kinase 1-like Protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30011581 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13Note: Hover over icons to view figure legend
Homology
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Human
Match: AAK1 (AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]) HSP 1 Score: 238.424 bits (607), Expect = 9.256e-68 Identity = 141/344 (40.99%), Postives = 206/344 (59.88%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F + + M + FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K P+ N + S P L P+K SE T + ++ + P ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTG--FTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNS--PIPAKLPEPVKASEAAAKKT---QPKARLTDPIPTTETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Human
Match: AAK1 (AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]) HSP 1 Score: 238.424 bits (607), Expect = 1.417e-66 Identity = 143/348 (41.09%), Postives = 207/348 (59.48%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K P+ N + S P L P+K SE T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIP--AKLPEPVKASEAAAKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Human
Match: AAK1 (AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]) HSP 1 Score: 237.654 bits (605), Expect = 6.984e-66 Identity = 143/348 (41.09%), Postives = 207/348 (59.48%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K P+ N + S P L P+K SE T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIP--AKLPEPVKASEAAAKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Human
Match: BMP2K (BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041]) HSP 1 Score: 228.024 bits (580), Expect = 3.385e-64 Identity = 134/336 (39.88%), Postives = 199/336 (59.23%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ +A+GG+ TV+ + + ALK++ VNN L C REI I++ + + I+ ++D + +++EV IL + + ++M + FTE +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P +++EI ++TTL+YR+PEM +LY G I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ ++L P+PE RP+I+Q++ F K PV N S P +AL PM SE + + + + + PT ETSI PR RPK
Sbjct: 51 VTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTEPEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLY---GGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIP--SALPEPMTASEAAARKSQIKARITDTIGPT---ETSIAPRQRPK 375
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Human
Match: BMP2K (BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041]) HSP 1 Score: 228.024 bits (580), Expect = 5.553e-62 Identity = 134/336 (39.88%), Postives = 199/336 (59.23%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ +A+GG+ TV+ + + ALK++ VNN L C REI I++ + + I+ ++D + +++EV IL + + ++M + FTE +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P +++EI ++TTL+YR+PEM +LY G I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ ++L P+PE RP+I+Q++ F K PV N S P +AL PM SE + + + + + PT ETSI PR RPK
Sbjct: 51 VTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTEPEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLY---GGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIP--SALPEPMTASEAAARKSQIKARITDTIGPT---ETSIAPRQRPK 375
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Celegans
Match: sel-5 (Serine/threonine-protein kinase sel-5 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ3]) HSP 1 Score: 184.111 bits (466), Expect = 8.017e-49 Identity = 142/383 (37.08%), Postives = 205/383 (53.52%), Query Frame = 1
Query: 148 KSITLKYE--SVVIDDKIAQGGYGTVYKAHSF-HKQYALKK-LCVNNEDKLLNCIRE-IFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIG--YPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTP-EPESRPNIYQLASVLFS-----------------------------MTSKSNPVQNCEKS-REPDLNALSLPMKESEFKMSNTNRQKKN-SKSSMPTQP--VETSIIPRNRPK 1173
K +TLK + V I+ +IA+GG+ VY A + ++ALK+ +NE +L C RE F+ + + + I+ FVDS + I+E +LT ++ N+ M S +Q T ++L I T++ EAV+ +H+ PIIHRDLKVENVLI P YVLCDFGSAT + + + ++ E+ + TT+ YRSPEM D +Y G E IG K+DIWALGVL+Y +CFF +PF +S L+I S + P P D +KVL Y+L + RP+IYQ + + F M SNP + S R P+ P +S KM++ ++Q + S SMP+ VETS+ PR RPK
Sbjct: 36 KGVTLKLDHTRVTIEKQIAEGGFAIVYVASDRKNNKFALKRQFTKDNEKQLEACCREHSFLKQCIGHKNIVEFVDSYTNCLGNGIWECMLLTEYHQKNVLQLMNERISQNQYLTNDEILSIFTDLCEAVSFIHN-RPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQILSVEKYGVEYVKSEVERNTTMCYRSPEMID-FYSGLE--IGLKSDIWALGVLLYRLCFFCVPFEESPLAIQSVNYQFPS-VPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEANHRKPLSEEIQNKKCTDAVPSLKSCIQLMRDGSNPRNKRDSSPRNPE-----APPIQSSSKMASLSQQVPSISNISMPSGSGTVETSVAPRLRPK 408
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Celegans
Match: sel-5 (Serine/threonine-protein kinase sel-5 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ3]) HSP 1 Score: 183.726 bits (465), Expect = 8.866e-48 Identity = 142/383 (37.08%), Postives = 205/383 (53.52%), Query Frame = 1
Query: 148 KSITLKYE--SVVIDDKIAQGGYGTVYKAHSF-HKQYALKK-LCVNNEDKLLNCIRE-IFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIG--YPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTP-EPESRPNIYQLASVLFS-----------------------------MTSKSNPVQNCEKS-REPDLNALSLPMKESEFKMSNTNRQKKN-SKSSMPTQP--VETSIIPRNRPK 1173
K +TLK + V I+ +IA+GG+ VY A + ++ALK+ +NE +L C RE F+ + + + I+ FVDS + I+E +LT ++ N+ M S +Q T ++L I T++ EAV+ +H+ PIIHRDLKVENVLI P YVLCDFGSAT + + + ++ E+ + TT+ YRSPEM D +Y G E IG K+DIWALGVL+Y +CFF +PF +S L+I S + P P D +KVL Y+L + RP+IYQ + + F M SNP + S R P+ P +S KM++ ++Q + S SMP+ VETS+ PR RPK
Sbjct: 36 KGVTLKLDHTRVTIEKQIAEGGFAIVYVASDRKNNKFALKRQFTKDNEKQLEACCREHSFLKQCIGHKNIVEFVDSYTNCLGNGIWECMLLTEYHQKNVLQLMNERISQNQYLTNDEILSIFTDLCEAVSFIHN-RPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQILSVEKYGVEYVKSEVERNTTMCYRSPEMID-FYSGLE--IGLKSDIWALGVLLYRLCFFCVPFEESPLAIQSVNYQFP-SVPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEANHRKPLSEEIQNKKCTDAVPSLKSCIQLMRDGSNPRNKRDSSPRNPE-----APPIQSSSKMASLSQQVPSISNISMPSGSGTVETSVAPRLRPK 408
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Celegans
Match: sel-5 (Serine/threonine-protein kinase sel-5 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ3]) HSP 1 Score: 183.726 bits (465), Expect = 8.866e-48 Identity = 142/383 (37.08%), Postives = 205/383 (53.52%), Query Frame = 1
Query: 148 KSITLKYE--SVVIDDKIAQGGYGTVYKAHSF-HKQYALKK-LCVNNEDKLLNCIRE-IFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIG--YPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTP-EPESRPNIYQLASVLFS-----------------------------MTSKSNPVQNCEKS-REPDLNALSLPMKESEFKMSNTNRQKKN-SKSSMPTQP--VETSIIPRNRPK 1173
K +TLK + V I+ +IA+GG+ VY A + ++ALK+ +NE +L C RE F+ + + + I+ FVDS + I+E +LT ++ N+ M S +Q T ++L I T++ EAV+ +H+ PIIHRDLKVENVLI P YVLCDFGSAT + + + ++ E+ + TT+ YRSPEM D +Y G E IG K+DIWALGVL+Y +CFF +PF +S L+I S + P P D +KVL Y+L + RP+IYQ + + F M SNP + S R P+ P +S KM++ ++Q + S SMP+ VETS+ PR RPK
Sbjct: 36 KGVTLKLDHTRVTIEKQIAEGGFAIVYVASDRKNNKFALKRQFTKDNEKQLEACCREHSFLKQCIGHKNIVEFVDSYTNCLGNGIWECMLLTEYHQKNVLQLMNERISQNQYLTNDEILSIFTDLCEAVSFIHN-RPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQILSVEKYGVEYVKSEVERNTTMCYRSPEMID-FYSGLE--IGLKSDIWALGVLLYRLCFFCVPFEESPLAIQSVNYQFP-SVPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEANHRKPLSEEIQNKKCTDAVPSLKSCIQLMRDGSNPRNKRDSSPRNPE-----APPIQSSSKMASLSQQVPSISNISMPSGSGTVETSVAPRLRPK 408
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Celegans
Match: gakh-1 (GAK Homolog [Source:UniProtKB/TrEMBL;Acc:Q20483]) HSP 1 Score: 106.686 bits (265), Expect = 8.844e-24 Identity = 84/274 (30.66%), Postives = 138/274 (50.36%), Query Frame = 1
Query: 181 IDDKIAQGGYGTVYKA-HSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQC-FTESDVLLIMTNIS-EAVACLHHFTSTPI--------IHRDLKVENVLIGYPMRYVLCDFGSATLK--EVRP-CDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYI----LTPEPESR 948
++ IA+GG+GTV+ A ++ KQ A+K + ++ + EI +++ + E I+ D+ S+ S + S C F+ +DVLL +S + V + +FT+ + IHRD+K EN+LI + LCDFGSAT K E+ P + R +Q+E+ ++TT RSPE+ D+Y + IG++ D WA+G L+Y + F PF S L+I++G++ P P + L + LTP P+ R
Sbjct: 41 VEKVIAKGGFGTVFLATNTKGKQVAVKIMLSHDAAATKDIDNEIDMMKKLQHENIIQLFDASAESRSSN---------------RSVKEYKISMEYCKFSIADVLLKYKEVSIDFVVRIIYFTTRALVYLHSVGAIHRDIKAENLLINGNGKLKLCDFGSATTKSIEMAPLSNSERLAVQEEMFKYTTPITRSPEVCDVYSN---WPIGKQQDNWAMGCLIYFVAFGEHPFDGSALAIINGKYKKP--PPVQQNQLSAFADLIAKCLTPNPDER 294
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Celegans
Match: unc-82 (pep chromosome:WBcel235:IV:7425729:7444660:1 gene:WBGene00006814.1 transcript:B0496.3h.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-82) HSP 1 Score: 72.0182 bits (175), Expect = 1.413e-12 Identity = 82/315 (26.03%), Postives = 134/315 (42.54%), Query Frame = 1
Query: 115 GYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKA--HSFHKQYA---LKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVF------ILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQF-TTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDS-----VLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPV 1008
G C+ +K+ K ++E I K+ G YG V A H F ++ A +KK + ++ L+ REI I+ ++ I+ I+EVF IL Y + E+ S E++ I I+ AV H + HRDLK+EN+L+ + DFG + D N ++ F + Y SPE+ + G G + D W+LG+L+Y + + S+PF V I G + P+ P + +L + +L PE R I+ +AS + ++ PV
Sbjct: 44 GAEPCSPTKKEKH---RFE---ITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVRIRREIRIMSALNHPNIIQ------------IYEVFENKDKIILVMEY--SSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHR---VAHRDLKLENILLDQNNNAKIADFGLSNYF----ADKNL------LTTFCGSPLYASPEIIN-----GTPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPE-TPSTASML--IRNMLRVNPERRATIFDIASHWWLNLEENMPV 317
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Fly
Match: Nak (gene:FBgn0015772 transcript:FBtr0081189) HSP 1 Score: 255.373 bits (651), Expect = 4.078e-74 Identity = 146/350 (41.71%), Postives = 208/350 (59.43%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAH------SFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
K T+ +V ++D +A+GG+ V+ A S +YALK++ VNNE L REI I N+ + I+ +VDS I T + + EV +L + ++ + M FTE +VL I +I+EAV+ LH + TPIIHRDLKVEN+L +VLCDFGSAT K + P +Q+EI ++TTL+YR+PEM DLY G I KADIWALG ++Y +CFFSLPFG+S L+I +GQF++PD YS + +++ Y+L P+ E RPNI+Q+ V F + K NPVQN K+ P+ + L +P ESE K + K ++ TS+ PR+RPK
Sbjct: 36 GKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKHHMLAMMNARLHVG--FTEPEVLNIFCDIAEAVSRLH-YCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLY---GGKSITTKADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVVEAGTSVAPRSRPK 379
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Fly
Match: Nak (gene:FBgn0015772 transcript:FBtr0340326) HSP 1 Score: 255.373 bits (651), Expect = 5.309e-74 Identity = 146/350 (41.71%), Postives = 208/350 (59.43%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAH------SFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
K T+ +V ++D +A+GG+ V+ A S +YALK++ VNNE L REI I N+ + I+ +VDS I T + + EV +L + ++ + M FTE +VL I +I+EAV+ LH + TPIIHRDLKVEN+L +VLCDFGSAT K + P +Q+EI ++TTL+YR+PEM DLY G I KADIWALG ++Y +CFFSLPFG+S L+I +GQF++PD YS + +++ Y+L P+ E RPNI+Q+ V F + K NPVQN K+ P+ + L +P ESE K + K ++ TS+ PR+RPK
Sbjct: 36 GKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKHHMLAMMNARLHVG--FTEPEVLNIFCDIAEAVSRLH-YCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLY---GGKSITTKADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVVEAGTSVAPRSRPK 379
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Fly
Match: Nak (gene:FBgn0015772 transcript:FBtr0081187) HSP 1 Score: 255.373 bits (651), Expect = 2.998e-71 Identity = 146/350 (41.71%), Postives = 208/350 (59.43%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAH------SFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
K T+ +V ++D +A+GG+ V+ A S +YALK++ VNNE L REI I N+ + I+ +VDS I T + + EV +L + ++ + M FTE +VL I +I+EAV+ LH + TPIIHRDLKVEN+L +VLCDFGSAT K + P +Q+EI ++TTL+YR+PEM DLY G I KADIWALG ++Y +CFFSLPFG+S L+I +GQF++PD YS + +++ Y+L P+ E RPNI+Q+ V F + K NPVQN K+ P+ + L +P ESE K + K ++ TS+ PR+RPK
Sbjct: 36 GKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKHHMLAMMNARLHVG--FTEPEVLNIFCDIAEAVSRLH-YCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLY---GGKSITTKADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVVEAGTSVAPRSRPK 379
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Fly
Match: Nak (gene:FBgn0015772 transcript:FBtr0340325) HSP 1 Score: 255.373 bits (651), Expect = 2.998e-71 Identity = 146/350 (41.71%), Postives = 208/350 (59.43%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAH------SFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
K T+ +V ++D +A+GG+ V+ A S +YALK++ VNNE L REI I N+ + I+ +VDS I T + + EV +L + ++ + M FTE +VL I +I+EAV+ LH + TPIIHRDLKVEN+L +VLCDFGSAT K + P +Q+EI ++TTL+YR+PEM DLY G I KADIWALG ++Y +CFFSLPFG+S L+I +GQF++PD YS + +++ Y+L P+ E RPNI+Q+ V F + K NPVQN K+ P+ + L +P ESE K + K ++ TS+ PR+RPK
Sbjct: 36 GKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKHHMLAMMNARLHVG--FTEPEVLNIFCDIAEAVSRLH-YCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLY---GGKSITTKADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVVEAGTSVAPRSRPK 379
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Fly
Match: CG1227 (gene:FBgn0037491 transcript:FBtr0339736) HSP 1 Score: 121.324 bits (303), Expect = 7.798e-30 Identity = 79/300 (26.33%), Postives = 147/300 (49.00%), Query Frame = 1
Query: 124 NCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAH--SFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVD-------SIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSAT---LKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPF------GDSV-LSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQL 966
C S + +++ + I +++A GG+ + S + YA+K++ ++ D +REI R + E ++ VD I+ T S +F +L + +L+ ++ E+ +L I + E + +H P+ HRDLK N+ + ++ D GS T L+ V D R LQDE + +++ YR+PE L+ I + DIW+LG ++Y +C+F+ P+ GDSV L++LSG +P+ Y++D+ +++ Y+L +P RP ++ +
Sbjct: 13 GCLFSCRKETLNINGSRYTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDYELKGQADIVINTTSTLF--IVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQR--LQDEAEERSSIVYRAPE---LFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSV 305
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Zebrafish
Match: aak1b (AP2 associated kinase 1b [Source:ZFIN;Acc:ZDB-GENE-091118-25]) HSP 1 Score: 246.514 bits (628), Expect = 9.235e-69 Identity = 140/351 (39.89%), Postives = 211/351 (60.11%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
++ T+ V +++ +A+GG+ V+ + + ALK++ VNNE L C REI I+R+++ + I+ F+DS I D++EVFIL +F ++ ++T F+E + L I + EAVA LH + TPIIHRDLKVEN+L+ YVLCDFGSAT+K P ++DEI ++TTL+YR+PEM +LY +I KADIWA+G L+Y +CFF+LPFG+S ++I G FT+PD+ YS D+ +++ Y+L P+P+ RP+IYQ++ F + + PVQN + S P L P++ SE + Q K ++ + P ETSI PR RPK
Sbjct: 37 GRNFTVGRHQVTVEETLAEGGFAIVFLVRTNQGVRCALKRMYVNNEHDLQVCKREIQIMRDLNGHKNIVGFLDSSITAVGGGDVWEVFILMDFCRGGQVVNLMNQRLQT------GFSEQEALQIFCDTCEAVARLHQY-KTPIIHRDLKVENILLHDRGHYVLCDFGSATMKFQNPQSEGVTAVEDEIKKYTTLSYRAPEMVNLYNG---KIITTKADIWAMGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSQDMHRLIRYMLEPDPDKRPDIYQVSFFAFKLARRDCPVQNVKNSPIP--AKLPEPIRASEAAAKKSQTQTK-ARLTDPIPTTETSITPRQRPK 374
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Zebrafish
Match: aak1a (AP2 associated kinase 1a [Source:ZFIN;Acc:ZDB-GENE-081105-101]) HSP 1 Score: 233.417 bits (594), Expect = 4.317e-67 Identity = 137/343 (39.94%), Postives = 204/343 (59.48%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
V +++ +A+GG+ V+ + + ALK++ VNNE L C EI I+R+ V + I+ F+DS I S D++EV IL +F ++ ++T F+ES+VL I + EAVA LH PIIHRDLKVEN+L+ YVLCDFGSA + P +++EI ++TTL+YR+PEM +LY G VI KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+I+Q++ F ++ + PVQN S P L P++ SE + + + ++ + P ETSI PR RPK G
Sbjct: 43 VTVEETVAEGGFAIVFLVRTHQGVRCALKRMYVNNEHDLQVCKMEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFSESEVLQIFCDTCEAVARLHQ-CKPPIIHRDLKVENILLHDRGHYVLCDFGSAINRSQNPQTEGVAVVEEEIKKYTTLSYRAPEMVNLY---GGMVITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSHDMHCLIRYMLEPDPDMRPDIFQVSYFAFKLSRRDCPVQNVHNSPIP--TKLPEPIRASE---AVAKKSQNKARLTDPVPTTETSIAPRQRPKAG 370
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Zebrafish
Match: aak1a (AP2 associated kinase 1a [Source:ZFIN;Acc:ZDB-GENE-081105-101]) HSP 1 Score: 233.802 bits (595), Expect = 3.668e-65 Identity = 139/343 (40.52%), Postives = 205/343 (59.77%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
V +++ +A+GG+ V+ + + ALK++ VNNE L C EI I+R+ V + I+ F+DS I S D++EV IL +F ++ ++T F+ES+VL I + EAVA LH PIIHRDLKVEN+L+ YVLCDFGSA + P +++EI ++TTL+YR+PEM +LY G VI KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+I+Q++ F ++ + PVQN S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 43 VTVEETVAEGGFAIVFLVRTHQGVRCALKRMYVNNEHDLQVCKMEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFSESEVLQIFCDTCEAVARLHQ-CKPPIIHRDLKVENILLHDRGHYVLCDFGSAINRSQNPQTEGVAVVEEEIKKYTTLSYRAPEMVNLY---GGMVITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSHDMHCLIRYMLEPDPDMRPDIFQVSYFAFKLSRRDCPVQNVHNSPIP--TKLPEPIRASE-AVAKKSQNKARLTDPVPT--TETSIAPRQRPKAG 370
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Zebrafish
Match: bmp2k (BMP2 inducible kinase [Source:ZFIN;Acc:ZDB-GENE-041212-72]) HSP 1 Score: 217.624 bits (553), Expect = 9.176e-61 Identity = 135/336 (40.18%), Postives = 190/336 (56.55%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQC-FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ IA+GG+ V+ A + + ALK++ VNN L REI I++ + + I+ ++DS ++EV IL + +K M FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P ++DEI ++TTL+YR+PEM +LY I KADIWALG L+Y +CFF+LPFG+S ++I G F VPD +S L ++ Y+L P+ E RP+IYQ++ F + K PV N S P +L P S+ + + + + S PT ETSI PR RPK
Sbjct: 40 VTVEELIAEGGFSMVFLARTHSGVRCALKRMYVNNVHDLNIFRREITIMKELSGHKNIVRYLDSTTNAVGDSVWEVLILMEYC--KAGQVVKQMNQRLHIGFTEAEVLNIFCDACEAVARLHQ-CKTPIIHRDLKVENILLNDQGNYVLCDFGSATHKVLLPHKDGITAVEDEIKKYTTLSYRAPEMINLYQG---KAITTKADIWALGCLLYKLCFFTLPFGESQVAICDGTFAVPDGSKFSSKLHGLIRYMLEPDQEKRPDIYQVSYFAFRLAGKECPVPNLFNSPLP--TSLPEPFTASDIAAKKSLTKARITDSVGPT---ETSIAPRQRPK 364
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Zebrafish
Match: bmp2k (BMP2 inducible kinase [Source:ZFIN;Acc:ZDB-GENE-041212-72]) HSP 1 Score: 217.238 bits (552), Expect = 1.246e-60 Identity = 135/336 (40.18%), Postives = 190/336 (56.55%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQC-FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ IA+GG+ V+ A + + ALK++ VNN L REI I++ + + I+ ++DS ++EV IL + +K M FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P ++DEI ++TTL+YR+PEM +LY I KADIWALG L+Y +CFF+LPFG+S ++I G F VPD +S L ++ Y+L P+ E RP+IYQ++ F + K PV N S P +L P S+ + + + + S PT ETSI PR RPK
Sbjct: 40 VTVEELIAEGGFSMVFLARTHSGVRCALKRMYVNNVHDLNIFRREITIMKELSGHKNIVRYLDSTTNAVGDSVWEVLILMEYC--KAGQVVKQMNQRLHIGFTEAEVLNIFCDACEAVARLHQ-CKTPIIHRDLKVENILLNDQGNYVLCDFGSATHKVLLPHKDGITAVEDEIKKYTTLSYRAPEMINLYQG---KAITTKADIWALGCLLYKLCFFTLPFGESQVAICDGTFAVPDGSKFSSKLHGLIRYMLEPDQEKRPDIYQVSYFAFRLAGKECPVPNLFNSPLP--TSLPEPFTASDIAAKKSLTKARITDSVGPT---ETSIAPRQRPK 364
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Xenopus
Match: aak1 (AP2 associated kinase 1 [Source:NCBI gene;Acc:100135375]) HSP 1 Score: 243.047 bits (619), Expect = 2.358e-70 Identity = 144/353 (40.79%), Postives = 208/353 (58.92%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL ++ ++ ++T FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +CFF+LPFG+S +SI G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + + PVQN + P L P+K E T + ++ + P ETSI PR RPKPG
Sbjct: 32 GRVFTIGRHQVTVDEVLAEGGFALVFLVRTSNGMRRALKRMYVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDYCRGGQVVNLMNQRLQT------GFTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKCQNPQTEGVTAVEDEIKKYTTLSYRAPEMVNLYSG---KMITTKADIWALGCLLYKLCFFTLPFGESQVSICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLAKRECPVQNVHDAVIP--VKLPEPIKAGEAAAKKT---QPKARLTDPVPTTETSIAPRQRPKPG 369
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Xenopus
Match: aak1 (AP2 associated kinase 1 [Source:NCBI gene;Acc:100135375]) HSP 1 Score: 243.047 bits (619), Expect = 7.001e-70 Identity = 144/353 (40.79%), Postives = 208/353 (58.92%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL ++ ++ ++T FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +CFF+LPFG+S +SI G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + + PVQN + P L P+K E T + ++ + P ETSI PR RPKPG
Sbjct: 32 GRVFTIGRHQVTVDEVLAEGGFALVFLVRTSNGMRRALKRMYVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDYCRGGQVVNLMNQRLQT------GFTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKCQNPQTEGVTAVEDEIKKYTTLSYRAPEMVNLYSG---KMITTKADIWALGCLLYKLCFFTLPFGESQVSICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLAKRECPVQNVHDAVIP--VKLPEPIKAGEAAAKKT---QPKARLTDPVPTTETSIAPRQRPKPG 369
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Xenopus
Match: aak1 (AP2 associated kinase 1 [Source:NCBI gene;Acc:100135375]) HSP 1 Score: 243.047 bits (619), Expect = 2.772e-68 Identity = 144/353 (40.79%), Postives = 208/353 (58.92%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL ++ ++ ++T FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +CFF+LPFG+S +SI G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + + PVQN + P L P+K E T + ++ + P ETSI PR RPKPG
Sbjct: 32 GRVFTIGRHQVTVDEVLAEGGFALVFLVRTSNGMRRALKRMYVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDYCRGGQVVNLMNQRLQT------GFTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKCQNPQTEGVTAVEDEIKKYTTLSYRAPEMVNLYSG---KMITTKADIWALGCLLYKLCFFTLPFGESQVSICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLAKRECPVQNVHDAVIP--VKLPEPIKAGEAAAKKT---QPKARLTDPVPTTETSIAPRQRPKPG 369
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Xenopus
Match: aak1 (AP2 associated kinase 1 [Source:NCBI gene;Acc:100135375]) HSP 1 Score: 243.432 bits (620), Expect = 1.824e-67 Identity = 144/353 (40.79%), Postives = 208/353 (58.92%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL ++ ++ ++T FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +CFF+LPFG+S +SI G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + + PVQN + P L P+K E T + ++ + P ETSI PR RPKPG
Sbjct: 32 GRVFTIGRHQVTVDEVLAEGGFALVFLVRTSNGMRRALKRMYVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDYCRGGQVVNLMNQRLQT------GFTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKCQNPQTEGVTAVEDEIKKYTTLSYRAPEMVNLYSG---KMITTKADIWALGCLLYKLCFFTLPFGESQVSICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLAKRECPVQNVHDAVIP--VKLPEPIKAGEAAAKKT---QPKARLTDPVPTTETSIAPRQRPKPG 369
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Xenopus
Match: aak1 (AP2 associated kinase 1 [Source:NCBI gene;Acc:100135375]) HSP 1 Score: 243.047 bits (619), Expect = 4.878e-67 Identity = 145/359 (40.39%), Postives = 205/359 (57.10%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDNLSSEMKTMCSSSQC-----------FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL ++ C Q FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +CFF+LPFG+S +SI G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + + PVQN + P L P+K E T + ++ + P ETSI PR RPKPG
Sbjct: 32 GRVFTIGRHQVTVDEVLAEGGFALVFLVRTSNGMRRALKRMYVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDY------------CRGGQVVNLMNQRLQTGFTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKCQNPQTEGVTAVEDEIKKYTTLSYRAPEMVNLYSG---KMITTKADIWALGCLLYKLCFFTLPFGESQVSICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLAKRECPVQNVHDAVIP--VKLPEPIKAGEAAAKKT---QPKARLTDPVPTTETSIAPRQRPKPG 369
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Mouse
Match: Aak1 (AP2 associated kinase 1 [Source:MGI Symbol;Acc:MGI:1098687]) HSP 1 Score: 238.81 bits (608), Expect = 8.516e-67 Identity = 142/348 (40.80%), Postives = 208/348 (59.77%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K PV N + S P L P+K SE + T + ++ + P ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIP--AKLPEPVKASEAAVKKT---QPKARLTDPIPTTETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Mouse
Match: Aak1 (AP2 associated kinase 1 [Source:MGI Symbol;Acc:MGI:1098687]) HSP 1 Score: 238.81 bits (608), Expect = 1.857e-66 Identity = 144/348 (41.38%), Postives = 208/348 (59.77%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K PV N + S P L P+K SE + T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIP--AKLPEPVKASEAAVKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Mouse
Match: Bmp2k (BMP2 inducible kinase [Source:MGI Symbol;Acc:MGI:2155456]) HSP 1 Score: 228.409 bits (581), Expect = 1.760e-64 Identity = 135/337 (40.06%), Postives = 201/337 (59.64%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVY--KAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ +A+GG+ TV+ + HS + ALK++ VNN L C REI I++ + + I+ ++D + +++EV IL + + ++M + FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P +++EI ++TTL+YR+PEM +LY G I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ ++L P+PE RP+I+Q++ F K PV N S P + L PM +E + + + + + PT ETSI PR RPK
Sbjct: 48 VTLEESLAEGGFSTVFLVRTHSGIR-CALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLY---GGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNINNSFLP--STLPEPMTATEAAARKSQMKARITDTIGPT---ETSIAPRQRPK 372
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Mouse
Match: Bmp2k (BMP2 inducible kinase [Source:MGI Symbol;Acc:MGI:2155456]) HSP 1 Score: 227.639 bits (579), Expect = 4.676e-62 Identity = 135/337 (40.06%), Postives = 201/337 (59.64%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVY--KAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ +A+GG+ TV+ + HS + ALK++ VNN L C REI I++ + + I+ ++D + +++EV IL + + ++M + FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P +++EI ++TTL+YR+PEM +LY G I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ ++L P+PE RP+I+Q++ F K PV N S P + L PM +E + + + + + PT ETSI PR RPK
Sbjct: 48 VTLEESLAEGGFSTVFLVRTHSGIR-CALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLNDAGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLY---GGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNINNSFLP--STLPEPMTATEAAARKSQMKARITDTIGPT---ETSIAPRQRPK 372
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Mouse
Match: Gak (cyclin G associated kinase [Source:MGI Symbol;Acc:MGI:2442153]) HSP 1 Score: 122.479 bits (306), Expect = 5.548e-28 Identity = 90/281 (32.03%), Postives = 141/281 (50.18%), Query Frame = 1
Query: 193 IAQGGYGTVYKAHSFH--KQYALKKLCVNNEDKLLNCIREIFILRNVHCEY-ILHFVDSIIY---QTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRP----CDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSV-LSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSN 1002
+A+GG+ VY+A ++YALK+L N E+K I+E+ L+ + I+ F + ++D+ E +LT L +K + +S +L I AV +H PIIHRDLKVEN+L+ LCDFGSAT P R +++EI++ TT YR+PE+ DLY + IG K DIWALG ++Y +CF PF D L I++G++++P + ++ +L PE R +I ++ L + + N
Sbjct: 46 LAEGGFAFVYEAQDLGSGREYALKRLLSNEEEKNRAIIQEVCFLKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKRVECKGPLSCDS-ILKIFYQTCRAVQHMHR-QKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQKRAMVEEEITRNTTPMYRTPEIVDLYSN---FPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPVNDTRYTVFHDLIRAMLKVNPEERLSIAEVVRQLQEIAAARN 321
BLAST of AP2-associated protein kinase 1-like Protein vs. UniProt/SwissProt
Match: sp|F1SPM8|AAK1_PIG (AP2-associated protein kinase 1 OS=Sus scrofa OX=9823 GN=AAK1 PE=2 SV=2) HSP 1 Score: 239.58 bits (610), Expect = 8.862e-66 Identity = 145/348 (41.67%), Postives = 207/348 (59.48%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTES+VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K PV N + S P L P+K SE T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTESEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSFFSFKLLKKECPVPNVQNSPIP--AKLPEPVKASEAAAKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. UniProt/SwissProt
Match: sp|Q3UHJ0|AAK1_MOUSE (AP2-associated protein kinase 1 OS=Mus musculus OX=10090 GN=Aak1 PE=1 SV=2) HSP 1 Score: 238.81 bits (608), Expect = 1.299e-65 Identity = 144/348 (41.38%), Postives = 208/348 (59.77%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K PV N + S P L P+K SE + T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIP--AKLPEPVKASEAAVKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. UniProt/SwissProt
Match: sp|F1MH24|AAK1_BOVIN (AP2-associated protein kinase 1 OS=Bos taurus OX=9913 GN=AAK1 PE=1 SV=2) HSP 1 Score: 238.81 bits (608), Expect = 1.547e-65 Identity = 145/354 (40.96%), Postives = 204/354 (57.63%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDNLSSEMKTMCSSSQC-----------FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F C Q FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY VI KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K P+ N + S P L P+K SE T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDF------------CRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KVITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIP--TKLPEPVKASEAAAKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. UniProt/SwissProt
Match: sp|Q2M2I8|AAK1_HUMAN (AP2-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=AAK1 PE=1 SV=3) HSP 1 Score: 237.654 bits (605), Expect = 3.354e-65 Identity = 143/348 (41.09%), Postives = 207/348 (59.48%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K P+ N + S P L P+K SE T + K +PT ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIP--AKLPEPVKASEAAAKKT-QPKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. UniProt/SwissProt
Match: sp|P0C1X8|AAK1_RAT (AP2-associated protein kinase 1 OS=Rattus norvegicus OX=10116 GN=Aak1 PE=1 SV=1) HSP 1 Score: 236.113 bits (601), Expect = 1.249e-64 Identity = 143/348 (41.09%), Postives = 207/348 (59.48%), Query Frame = 1
Query: 160 LKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ + V +D+ +A+GG+ V+ + + + ALK++ VNNE L C REI I+R++ + I+ ++DS I S D++EV IL +F ++ ++T FTE++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P ++DEI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+F+LPFG+S ++I G FT+PD+ YS D + L Y+L P+P+ RP+IYQ++ F + K PV N + S P L P+K SE + T + ++ + P ETSI PR RPK G
Sbjct: 41 IGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFTENEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSG---KIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSQD-MHCLIYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIP--TKLPEPVKASEAAVKKT---QPKARLTDPIPTTETSIAPRQRPKAG 372
BLAST of AP2-associated protein kinase 1-like Protein vs. TrEMBL
Match: A0A0X3P1N6 (BMP-2-inducible protein kinase (Fragment) OS=Schistocephalus solidus OX=70667 GN=BMP2K PE=4 SV=1) HSP 1 Score: 265.774 bits (678), Expect = 2.189e-78 Identity = 136/329 (41.34%), Postives = 208/329 (63.22%), Query Frame = 1
Query: 88 ENEDIYRNVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSF-HKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKES 1071
ENE I ++N + K + + ++ IA+GG+G V + S + +A+K+ CVNN+ L RE+ I+ ++ + IL ++DS I +T+ I+EV ++T+FYP +++ + +Q F E++VL ++ ++ EAV+ LHH TPIIHRDLK+EN+LI +VLCDFGSAT + + P Q+EI + TTLAYR+PEM DLY +GG+ IG DIWALG ++Y +CFFSLPFG + L+I +GQF +PDH YS L K++ ++L+ E RP+I+Q+AS+ FS+ + NPV N S+ P +L+ P+ ES
Sbjct: 12 ENELISSQSAHHNSL--QTGKQFFVGNHKLTVEGIIAEGGFGVVCRVRSQDGRVFAMKRTCVNNKSDLATVKREVTIVSSLSHKNILKYIDSTITETEPGIYEVLLVTSFYPGSVAQVLTERRQKNQRFLETEVLRVLCDVCEAVSRLHH-CETPIIHRDLKIENILIDGQKNFVLCDFGSATSRVLHPGKHGPLRCQEEIEKHTTLAYRAPEMVDLYTNGGQP-IGPPVDIWALGCVVYGLCFFSLPFGANALAIQTGQFVIPDHSSYSPRLHKLIKFMLSVEALKRPDIFQVASLAFSLLGRPNPVLNVNASQLPSWQSLTEPLTES 336
BLAST of AP2-associated protein kinase 1-like Protein vs. TrEMBL
Match: A0A139WLH0 (AP2-associated protein kinase 1-like Protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC000132 PE=4 SV=1) HSP 1 Score: 273.478 bits (698), Expect = 1.315e-77 Identity = 163/412 (39.56%), Postives = 237/412 (57.52%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPV--ETSIIPRNRPKPGGKLQ-NYNNCHNTVQKPXXXXXXXXXXXXXXPDLLDFESQLEIESNNFETANQFSKTKSVDKL 1365
K T+ ++V ++D +A+GG+ VY + +YALK++ VNNE L REI I ++ + I+ +VDS + T ++EV +L + +N+ MK ++ FTE +VL I + EAV+ LHH TPIIHRDLKVEN+L+G YV+CDFGSAT K + P D +++EI ++TTL+YR+PEM D+Y I KADIWALG L+Y +CFF+LPFG+S L+I SG F++PD+ YS L +++ Y+L P+P+ RP+I+Q++ V F + SK NPV+N KS P L L +P ESE K + K P P+ TS++PR RPK N NN T+ P+ + K + P + + S NF+T F K +D L
Sbjct: 24 GKVFTVGRQTVTVEDILAEGGFAIVYLVKGTNGTRYALKRMYVNNEQDLNVAKREIQIASSLSGHKNIIGYVDSSLTATGGGVYEVLLLMPYCQENVFGLMKQRGKAN--FTEHEVLTIFCDTCEAVSRLHH-CKTPIIHRDLKVENILVGENGNYVICDFGSATAKVLNPADKGVAPVEEEIKRYTTLSYRAPEMVDMYCG---KPITTKADIWALGCLLYRLCFFTLPFGESTLAIQSGNFSIPDNSKYSKGLHQLMRYMLEPDPDKRPDIFQVSCVAFQLLSKENPVKNLMKSPIPKLEDLPVPPFESELKKAQVKVYNKT-----PAAPIVEGTSVMPRQRPKGSSTTPLNLNNIPLTLS-PSPTTSKKSQSPVTQPPVTTYPS-------NFQTQPTFEPVKQLDSL 416
BLAST of AP2-associated protein kinase 1-like Protein vs. TrEMBL
Match: A0A023G4X8 (Putative ark protein kinase family (Fragment) OS=Amblyomma triste OX=251400 PE=2 SV=1) HSP 1 Score: 264.233 bits (674), Expect = 4.999e-77 Identity = 149/345 (43.19%), Postives = 211/345 (61.16%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAH-SFHKQYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
K T+ +V ++D IA+GG+ V+ S + +YALK++ VN E L C REI I N+ + I+ FVDS+I ++EV +L ++Y ++ M S F+E +VL I +I EAV+ LHH TPI+HRDLKVEN+LI YVLCDFGSAT K + P +++EI ++TTLAYR+PEM +LY +I KADIWALG L+Y +CFFSLPFG+S L+I SG FT+PD+ YS + ++ Y+L +PE RP+I+Q++ V FS+ K PVQN S P++ L +P +SE K+S++ K +S TS+ PR RPK
Sbjct: 51 GKVFTVGRHTVTVEDVIAEGGFAIVFLVKGSNNVRYALKRMFVNEEHGLNVCKREIQIASNLSGHKNIIGFVDSVINHVGGGVYEVLMLMHYYKGHVLQLMNDKLQSG--FSEQEVLKIFCDICEAVSRLHH-CQTPIVHRDLKVENILISDSGHYVLCDFGSATAKSLNPQTQGVAVVEEEILKYTTLAYRAPEMVELYSG---KLITTKADIWALGCLLYKLCFFSLPFGESALAIQSGNFTIPDNSRYSKQMHSLIRYMLEVQPEKRPDIFQVSYVAFSLAGKECPVQNLHNSPIPNIEQLPVPQCDSEGKLSSS----KPPRSLQVPVAEGTSVAPRQRPK 385
BLAST of AP2-associated protein kinase 1-like Protein vs. TrEMBL
Match: A0A4S2L7X9 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009198 PE=4 SV=1) HSP 1 Score: 266.544 bits (680), Expect = 1.034e-75 Identity = 146/346 (42.20%), Postives = 210/346 (60.69%), Query Frame = 1
Query: 172 SVVIDDKIAQGGYGTVYKAHSFHKQ-YALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKM--------SNTNRQKKNSKSSMPTQPVETSII---PRNRPK 1173
S+V+D+ IA+GG+G V++ S Q YALK+ CVN+ + C REI I+ ++ + IL +DS I + IFEV +LT +YP +LS + Q TE +VL I ++ EAV LHH TPIIHRDLKVEN+LI +VLCDFGSAT + + P + Q+EI+++TTLAYR+PEM +LY + +G + DIWALG L+Y +CF +LPFGDS L+I SG +++PD PYS+ L +++ Y+L + RP+I+Q++++ FS+T++ NP QN P LS+P +ES+ K T R S S P T+ I PR RP+
Sbjct: 46 SLVVDEIIAEGGFGVVFRVRSQQGQHYALKRTCVNSAQNMAICKREITIVSSLSHKNILRSIDSRINRIQDGIFEVLLLTAYYPGSLSHLLSERQQHHQRLTEVEVLRIFCDLCEAVCRLHH-CKTPIIHRDLKVENILIDERQNFVLCDFGSATSRVLHPAVHGLERCQEEINKYTTLAYRAPEMINLYSNVP---LGPQIDIWALGCLLYCLCFTALPFGDSALAIQSGIYSIPDTSPYSERLHRLIGYLLQIDAAKRPDIFQVSALAFSLTARPNPAQNLNNLPVPHWQDLSIPPRESQLKALRTQPLVHEPTKRSSPLSSGSQLATPFSTTSITLAPRQRPR 387
BLAST of AP2-associated protein kinase 1-like Protein vs. TrEMBL
Match: A0A3R7H2D9 (AP2-associated protein kinase 1 OS=Clonorchis sinensis OX=79923 GN=AAK1 PE=4 SV=1) HSP 1 Score: 267.7 bits (683), Expect = 1.896e-75 Identity = 147/346 (42.49%), Postives = 210/346 (60.69%), Query Frame = 1
Query: 172 SVVIDDKIAQGGYGTVYKAHSFHKQY-ALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKM--------SNTNRQKKNSKSSMPTQPVETSII---PRNRPK 1173
S+V+D+ IA+GG+G V++ S QY ALK+ CVN+ L C REI I+ ++ + IL +DS I + IFEV +LT +YP +LS + Q TE +VL I ++ EAV LHH TPIIHRDLKVEN+LI +VLCDFGSAT + + P + Q+EI+++TTLAYR+PEM +LY + +G + DIWALG L+Y +CF +LPFGDS L+I SG +++PD PYS+ L +++ Y+L + RP+I+Q++++ FS+T++ NP QN P LS+P +ES+ K T R S + P TS I PR RP+
Sbjct: 46 SLVVDEIIAEGGFGVVFRVRSQQGQYYALKRTCVNSAQNLAICKREITIVSSLSHKNILRSIDSRINRIQDGIFEVLLLTAYYPGSLSHLLSERQQHQQRLTEVEVLRIFCDLCEAVCRLHH-CKTPIIHRDLKVENILIDERQNFVLCDFGSATSRVLHPAVHGLERCQEEINKYTTLAYRAPEMINLYSNVP---LGPQIDIWALGCLLYCLCFTALPFGDSALAIQSGIYSIPDTSPYSERLHRLIGYLLQIDAAKRPDIFQVSALAFSLTARPNPAQNLNNLPVPHWQDLSMPPRESQLKALRTQPVVHEPTKRSSPLSSGNQLATPFSTSSITLAPRQRPR 387
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Cavefish
Match: aak1b (AP2 associated kinase 1b [Source:ZFIN;Acc:ZDB-GENE-091118-25]) HSP 1 Score: 243.817 bits (621), Expect = 3.222e-72 Identity = 142/353 (40.23%), Postives = 211/353 (59.77%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
++ T+ V +++ +A+GG+ V+ + + ALK++ VNNE L C REI I+R++ + I+ F+DS + Q D++EVFIL +F ++ ++T F+E++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K P +++EI ++TTL+YR+PEM +LY +I KADIWALG L+Y +C+FSLPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ + + PVQN + S P N L P++ SE + Q K ++ + P ETSI PR RPK G
Sbjct: 36 GRNFTVGRHQVTVEETLAEGGFAIVFLVRTNQGVRCALKRMYVNNEYDLQVCRREIQIMRDLSGHKNIVGFLDSSVTQVGGGDVWEVFILMDFCKGGQVVNLMNQRLQTG------FSEAEVLQIFCDSCEAVAQLHQ-CKTPIIHRDLKVENILLHEKGHYVLCDFGSATKKFQNPQSEGVTIVEEEIKKYTTLSYRAPEMVNLY---NGKIITTKADIWALGCLLYKLCYFSLPFGESQVAICDGNFTIPDNSRYSHDMHCLIRYMLEPDPDKRPDIYQVSHFACRLARRDCPVQNVKNSPLP--NKLPEPVRASEAAAKKSQTQTK-ARLTDPIPTTETSITPRQRPKAG 375
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Cavefish
Match: ENSAMXT00000003200.2 (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:103021556]) HSP 1 Score: 239.58 bits (610), Expect = 8.562e-67 Identity = 146/359 (40.67%), Postives = 205/359 (57.10%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDNLSSEMKTMCSSSQC-----------FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ IA+GG+ V+ + + ALK++ VNNE L C REI I+R+ V + I+ F+DS I S D++EV IL +F C Q F+E +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT + P +++EI ++TTL+YR+PEM +LY G +I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K VQN S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 36 GRVFTIGRYQVTVDETIAEGGFAIVFLVRTHQGVRCALKRMYVNNEHDLQVCKREIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDF------------CRGGQVVNLMNQRLQTGFSEPEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQAEGAATVEEEIKKYTTLSYRAPEMVNLY---GGKMITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDIRPDIYQVSHFAFKLARKDCSVQNVHNSPIP--TKLPEPIRASE-AVAKKSQTKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Cavefish
Match: ENSAMXT00000054610.1 (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:103021556]) HSP 1 Score: 240.35 bits (612), Expect = 1.516e-66 Identity = 146/359 (40.67%), Postives = 205/359 (57.10%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDNLSSEMKTMCSSSQC-----------FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ IA+GG+ V+ + + ALK++ VNNE L C REI I+R+ V + I+ F+DS I S D++EV IL +F C Q F+E +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT + P +++EI ++TTL+YR+PEM +LY G +I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K VQN S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 36 GRVFTIGRYQVTVDETIAEGGFAIVFLVRTHQGVRCALKRMYVNNEHDLQVCKREIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDF------------CRGGQVVNLMNQRLQTGFSEPEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQAEGAATVEEEIKKYTTLSYRAPEMVNLY---GGKMITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDIRPDIYQVSHFAFKLARKDCSVQNVHNSPIP--TKLPEPIRASE-AVAKKSQTKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Cavefish
Match: ENSAMXT00000051497.1 (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:103021556]) HSP 1 Score: 240.35 bits (612), Expect = 1.948e-66 Identity = 146/359 (40.67%), Postives = 205/359 (57.10%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDNLSSEMKTMCSSSQC-----------FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ IA+GG+ V+ + + ALK++ VNNE L C REI I+R+ V + I+ F+DS I S D++EV IL +F C Q F+E +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT + P +++EI ++TTL+YR+PEM +LY G +I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K VQN S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 36 GRVFTIGRYQVTVDETIAEGGFAIVFLVRTHQGVRCALKRMYVNNEHDLQVCKREIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDF------------CRGGQVVNLMNQRLQTGFSEPEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQAEGAATVEEEIKKYTTLSYRAPEMVNLY---GGKMITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDIRPDIYQVSHFAFKLARKDCSVQNVHNSPIP--TKLPEPIRASE-AVAKKSQTKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Cavefish
Match: ENSAMXT00000042526.1 (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:103021556]) HSP 1 Score: 240.35 bits (612), Expect = 2.113e-66 Identity = 146/359 (40.67%), Postives = 205/359 (57.10%), Query Frame = 1
Query: 145 SKSITLKYESVVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDNLSSEMKTMCSSSQC-----------FTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
+ T+ V +D+ IA+GG+ V+ + + ALK++ VNNE L C REI I+R+ V + I+ F+DS I S D++EV IL +F C Q F+E +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT + P +++EI ++TTL+YR+PEM +LY G +I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS D+ ++ Y+L P+P+ RP+IYQ++ F + K VQN S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 36 GRVFTIGRYQVTVDETIAEGGFAIVFLVRTHQGVRCALKRMYVNNEHDLQVCKREIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDF------------CRGGQVVNLMNQRLQTGFSEPEVLQIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQAEGAATVEEEIKKYTTLSYRAPEMVNLY---GGKMITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDIRPDIYQVSHFAFKLARKDCSVQNVHNSPIP--TKLPEPIRASE-AVAKKSQTKARLTDPIPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006448.1 (pep scaffold:Pmarinus_7.0:GL476771:264361:311032:-1 gene:ENSPMAG00000005802.1 transcript:ENSPMAT00000006448.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 244.588 bits (623), Expect = 2.717e-69 Identity = 146/342 (42.69%), Postives = 202/342 (59.06%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAH-SFHKQYALKKLCVNNEDKLLNCIREIFILRNV--HCEYILHFVDSIIYQTDSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESE-FKMSNTNRQKKNSKSSM--PTQPVETSIIPRNRPKPG 1179
V +++ +A+GG+ V+ S + ALK++ VNNE L C REI I++ + H + + SI QT S ++EV IL + ++M S+ FTE +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P ++DEI ++TTL+YR+PEM +LY I K+DIWALG L+Y +CFF+LPFG+S ++I G FT+PDH YS ++ ++ Y+L P+P+SRP IYQ+A F ++ K P+ N +N LSLP K E K S +K SK+ + P ETSI PR RPK G
Sbjct: 45 VTVEEVLAEGGFAIVFLVKTSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIVGYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTG--FTECEVLRIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQAHGVSAVEDEIKKYTTLSYRAPEMVNLYNG---TPITAKSDIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDHSRYSHEMHCLIRYMLEPDPDSRPEIYQVACFAFKLSGKECPILN--------VNGLSLPNKLPEPLKASEAAARKTQSKTKLTETVGPTETSIAPRQRPKAG 372
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007073.1 (pep scaffold:Pmarinus_7.0:GL477321:233302:247915:1 gene:ENSPMAG00000006397.1 transcript:ENSPMAT00000007073.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 231.106 bits (588), Expect = 1.015e-67 Identity = 141/327 (43.12%), Postives = 194/327 (59.33%), Query Frame = 1
Query: 202 GGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSII-YQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQ-CFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRP 1170
GG+ V+ A + Q ALK++ VNNE L C REI I++ + + I+ ++DS I Q ++++EV +L F + M Q F+E +VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + +++EI ++TTL+YRSPEM +LY I KADIWALG L+Y +CFFSLPFG+S ++I G FTVPD+ YS DL ++ Y+L PEP++RP+I+Q+ASV F + K PV N + P + L P+ SE + R + +K P P ETSI+PR P
Sbjct: 1 GGFSVVFLARTHSGIQCALKRMYVNNEHDLKVCKREITIMKELSGHKNIVGYLDSAINAQAATEVWEVLVLMEFCKGAAGQVVNQMNRRLQNGFSEREVLSIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKVLNTQVSGVPAVEEEIQKYTTLSYRSPEMVNLYSGIP---ITTKADIWALGCLLYKLCFFSLPFGESQVAICDGSFTVPDNSKYSHDLHCLIRYMLEPEPDTRPDIFQVASVGFKLAKKDCPVPNLHSAPVP--SRLPEPLLASE---AAARRIQVKTKLPDPCGPTETSIVPRQIP 318
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Sea Lamprey
Match: stk16 (serine/threonine kinase 16 [Source:ZFIN;Acc:ZDB-GENE-050417-102]) HSP 1 Score: 84.7297 bits (208), Expect = 3.988e-18 Identity = 75/292 (25.68%), Postives = 132/292 (45.21%), Query Frame = 1
Query: 112 VGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSFH--KQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYP-DNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFT--TLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPF------GDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPN 954
+G NC S+ SI K + +++ +GG+ V H + YALK++ +++D +RE+ + R +L S + + EV++L +Y L E++ + + TE ++ I I + +H HRDLK NVL+ VL D GS + + +R+ + ++++ T++YR+PE L+ +I + DIW+LG +++ + F PF GDSV + VP YS L K+L ++ +P RP
Sbjct: 1 MGQANCICSRGIFSIDDKRYFFI--EQLGEGGFSYVDLVEGAHNGRFYALKRIVCHDKDDHKGALREVEMHRAFRHPNVLPLEGSRVVERGPKC-EVWLLLPYYQRGTLWDELEKLRNKHSFMTEERIVGIFRGICSGLKDIH---DKGFAHRDLKPTNVLLSDEDVPVLMDLGSMEKARIEIKN-SREAMALQVTRAVRCTISYRAPE---LFTVPSHCIIDARTDIWSLGCVLFAMMFLEGPFDGVFQRGDSVALAVQSSVNVPSSSRYSQPLRKLLTSLMDVDPSERPT 282
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Sea Lamprey
Match: phkg1b (phosphorylase kinase, gamma 1b (muscle) [Source:ZFIN;Acc:ZDB-GENE-050522-52]) HSP 1 Score: 77.0258 bits (188), Expect = 3.512e-15 Identity = 68/232 (29.31%), Postives = 109/232 (46.98%), Query Frame = 1
Query: 277 EDKLLNCIREIFILRNVHCE-YILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDS-----VLSILSGQ--FTVPDHCPYSDDLLKVLNYILTPEPESR 948
ED + ++E+ IL+ V +I+ +D+ Y++ + F VF L E+ + +E D IM +I E V LH + I+HRDLK EN+L+ M L DFG + ++RP + R+ T Y SPE+ D G++ D+WA GV+MY + S PF + I+ G+ F+ P+ SD + +++ +L EPE R
Sbjct: 69 EDIYSSTVKEVDILKAVSGHPHIITLIDA--YESSTFFFLVFDLMK------RGELFDYLTEKVALSEKDTRSIMRSIFEVVHFLH---AKNIVHRDLKPENILLDDNMNIRLSDFGFSM--QLRPGERLRE-------LCGTPGYLSPELLKCSMDESHPGYGKEVDLWACGVIMYTLLAGSPPFWHRKQMTMLRLIMDGKYDFSTPEWEDRSDTVKDLISRLLVVEPEKR 280
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Sea Lamprey
Match: NIM1K (NIM1 serine/threonine protein kinase [Source:HGNC Symbol;Acc:HGNC:28646]) HSP 1 Score: 72.0182 bits (175), Expect = 1.189e-13 Identity = 59/185 (31.89%), Postives = 86/185 (46.49%), Query Frame = 1
Query: 430 SSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQF-TTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPF-----GDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQL 966
E+ T S+ + L+ I+ AV +H ++HRDLK ENV + DFG +T V P + +S F + Y +PE L+ D + +G + D+WALGVL++ I +LPF G LSIL G F+VP P S ++ IL P P+ RP Q+
Sbjct: 124 GGELFTRVSTVGALPHDEAKLVFAQITAAVKHMHECG---VVHRDLKAENVFYAGNCWVKVGDFGFST--TVTP--------NERLSTFCGSPPYAAPE---LFRD--QSYLGPQVDVWALGVLLFFIASGTLPFRADTVGKLKLSILDGCFSVPLRVPAS--CCNLITTILRPLPDERPTAAQI 288
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Yeast
Match: ARK1 (Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication [Source:SGD;Acc:S000004965]) HSP 1 Score: 145.976 bits (367), Expect = 5.516e-37 Identity = 106/325 (32.62%), Postives = 165/325 (50.77%), Query Frame = 1
Query: 112 VGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKA-------HSFHKQYALKKLCVNNEDKLLNCIREIFILRNV-HCEYILHFVDSIIYQT--DSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDL---QDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPF---GDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREP 1035
+G YN +T+ V I + GG+ VY A HS LK++ V ++ L E+ +R + + Y++ ++DS + + +EVF+L + L M T + E ++L IM+ +++ VA +H P+IHRD+K+ENVLI Y LCDFGS +RP N Q+L Q +I + TT YRSPEM D + I K+DIWALG+ +Y +C+++ PF GD L+ILSG+F P + YS+ L ++ IL +P RPN+YQL + M + P+ + + + P
Sbjct: 6 IGTYNV-----GTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNR--LHEFEILQIMSQVTQGVAAMHAL-QPPLIHRDIKIENVLISANNEYKLCDFGSVC-GIIRPPR-NSQELSYVQQDILKNTTAQYRSPEMIDTFRG---LPIDEKSDIWALGIFLYKLCYYTTPFEKGGD--LAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAP 315
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Yeast
Match: PRK1 (Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001357]) HSP 1 Score: 135.191 bits (339), Expect = 3.553e-33 Identity = 101/302 (33.44%), Postives = 156/302 (51.66%), Query Frame = 1
Query: 193 IAQGGYGTVYKA-------HSFHKQYALKKLCVNNEDKLLNCIRE----IFILRNVHCEYILHFVDSIIYQTDSDI-FEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQD---LQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSV-LSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNA 1047
+ GG+ VY A +S LK++ V ++ L N +R + +LRN ++++ ++DS ++ + I +EVF+L F L M T + ES++L IM+ + + +H P+IHRD+K+ENVLI + Y +CDFGS + +RP N Q+ +Q +I TT YRSPEM DLY I K+DIWALGV +Y IC+++ PF S IL ++ P YSD L ++ +L P RPNI Q+ + + +K P++N R + NA
Sbjct: 28 LTSGGFAQVYTAEISPPDPYSNANIACLKRVIVPHKQGL-NTLRAEVDAMKLLRN--NKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNR--LQESEILEIMSQTVQGITAMHAL-QPPLIHRDIKIENVLISHDGLYKVCDFGSVS-GVIRPPR-NTQEFNYVQHDILTNTTAQYRSPEMIDLYRG---LPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQNKPCPIRNFYLLRAMNQNA 318
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Yeast
Match: AKL1 (Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization [Source:SGD;Acc:S000000263]) HSP 1 Score: 112.079 bits (279), Expect = 8.874e-26 Identity = 80/246 (32.52%), Postives = 129/246 (52.44%), Query Frame = 1
Query: 253 LKKLCVNNEDKLLNCIREIFILRNVH-CEYILHFVDSIIYQTDSDI--FEVFILTNFYPD-NLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQD---LQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFG-DSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQL 966
LK++ V +E+ L E+ +++ + I+ + DS + + FEV +L P+ +L M S+ TE++++ IM +++ +++ +H+ + +IHRD+K+ENVL+ + L DFGS + P QD L I TT YRSPEM DLY I K+DIWALGV +Y + FF+ PF +IL ++ P + YS L+ ++ +L P RPNIYQ+
Sbjct: 77 LKRVLVQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTK--LTEAEIVKIMYDVALSISQMHYLPVS-LIHRDIKIENVLVDAKNNFKLADFGSTST--CFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRC---LPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPVN-KYSSKLINLIIIMLAENPNLRPNIYQV 313
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Yeast
Match: PSK2 (PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405]) HSP 1 Score: 75.485 bits (184), Expect = 2.078e-14 Identity = 49/152 (32.24%), Postives = 74/152 (48.68%), Query Frame = 1
Query: 511 EAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQL 966
+ VA + H I+HRD+K ENV++ L DFGSA + P DV T+ Y +PE+ GG G+ DIWALGVL+Y I + P+ + + IL G+ S++ + ++ ILT E + RP I ++
Sbjct: 958 QVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDV----------FVGTMDYAAPEVL-----GGSSYKGKPQDIWALGVLLYTIIYKENPYYN-IDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEI 1093
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 74.7146 bits (182), Expect = 3.299e-14 Identity = 76/284 (26.76%), Postives = 127/284 (44.72%), Query Frame = 1
Query: 193 IAQGGYGTVYKAHSFH--KQYALKKLCVNNE-DKLLNCIREIFILRNV-HCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPE--MADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCP------YSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPV 1008
I +G +G VYK ++ + YA+K L ++++ D++ + REI L ++ I + S Y D+ ++ I+ + +L S ++ E + +IM + A+ C+H +IHRD+K NVLI LCDFG A +V + RQ + T + +PE M +YYD K DIW+LG+ Y I + P+ D V ++ + Q + P YS L + + L +P+ R + L F K+ P
Sbjct: 29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGS--YLKDTSLW--IIMEHCAGGSLRSLLR-----PGKIDEKYIGVIMRELLVALKCIHKDN---VIHRDIKAANVLITNEGNVKLCDFGVAA--QVNQTSLRRQTMAG------TPYWMAPEVIMEGVYYD-------TKVDIWSLGITTYEIATGNPPYCD-VEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPT 284
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Nematostella
Match: EDO39786 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S938]) HSP 1 Score: 233.802 bits (595), Expect = 4.931e-70 Identity = 140/361 (38.78%), Postives = 207/361 (57.34%), Query Frame = 1
Query: 109 NVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSFHKQ-YALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPGGK 1185
++G ++CTV ++ IA+GG+ V+ + Q ALK++ VNN L C +EI I++ V + + F+DS I QT DIFEV IL + + ++ ++ F+ES VL I T+ EAVA LH S P+IHRDLKVEN+L +VLCDFGSAT K+ P +++EI ++TTL YR+PEM DLY +I K+DIWALG L+Y +CFF+LPFG+S L+I + QFT P++ YS L +++YIL P+P++RP+IYQ++ F + + PV N KS P LP + + + + +R + + PV TS+ PR RP+ G+
Sbjct: 23 SIGRFHCTV----------------EEIIAEGGFALVFLVKTPQGQRLALKRVSVNNSHDLDICKQEISIMKLVSGHKNTIRFIDSKILQTSPDIFEVLILMEYCKEGHVVQLMNERINTG-FSESLVLKIFTDACEAVALLHQ-ASPPVIHRDLKVENILCSDRRDFVLCDFGSATRKDTDPQADGVTHVEEEIQKYTTLPYRAPEMVDLY---SGKIISTKSDIWALGCLLYKLCFFTLPFGESPLAIQNAQFTFPENSRYSKGLHSLISYILDPDPDTRPDIYQVSFEAFRLRGQDCPVLNVNKSSVPQF----LPEPKQKPDVVDKSRTAR-----LRDGPVTTSLTPRQRPRAAGQ 353
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Nematostella
Match: EDO43926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX98]) HSP 1 Score: 141.739 bits (356), Expect = 6.344e-35 Identity = 100/286 (34.97%), Postives = 153/286 (53.50%), Query Frame = 1
Query: 181 IDDKIAQGGYGTVYKAHSFH--KQYALKKLCVNNEDKLLNCIREIFILRNV--HCEYILHFVDSIIYQTDSD--IFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCD----VNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSV-LSILSGQFTVP----DHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTS 993
I IA+GGYG V+ A K+YALK+L +E N ++EI +L+ + H + + + + + +S + E ILT + + Q F+ +L I + AV+ +H S PIIHRDLK+EN+LIG + LCDFGSAT + + P D +NR +DEI + TT YR+PEM DLY + + KADIWALG +++ +CF PF DS L I++ ++T+P ++ Y D ++N L PE RP I + + L ++ +
Sbjct: 17 IKRVIAEGGYGFVFVAQDGKTGKEYALKRLMAGDEAANKNILQEINMLKRLRGHPNVVQFYSAASLGEKESGHGMTEYLILTELCTGIVDRVYQV--RDGQPFSPDQILRIFYQLCRAVSHMHK-QSPPIIHRDLKIENMLIGSKGQIKLCDFGSATTEPLTPDDSWTALNRSLAEDEIQRNTTPMYRAPEMVDLYSN---LPVTEKADIWALGCVLFYLCFMEHPFEDSAKLRIINAKYTIPEMDREYTMYHD----LINSTLVVHPEDRPCIRDILTQLEALAA 292
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Nematostella
Match: EDO33625 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRN4]) HSP 1 Score: 79.337 bits (194), Expect = 7.380e-16 Identity = 66/237 (27.85%), Postives = 116/237 (48.95%), Query Frame = 1
Query: 178 VIDDKIAQGGYGTVYKAHS--FHKQYALKKLCVNN--EDKLLNCI-REIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPE-MADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFT 870
+ D + +G Y V A+S KQ A+K + +D L + REI ++++++ ++ ++I +T S I+ + L + + ++ S+ E++ L + +AV LH+ ++HRDLK EN+L+ R ++ DFG A + V D ++ L + AY PE + + YDG ADIW+LGV++Y + SLPF D+ L +L Q +
Sbjct: 62 ALGDTLGKGSYAVVKAAYSRKLKKQVAVKIVTKKKAPDDYLTKFLPREIQVMKHLNHSNVVSLHEAI--ETSSRIYIILDLAD------NGDLLEYIRSNGAIPENEARLFYHQLVDAVEYLHN---KGVVHRDLKCENILLNRDNRILISDFGFARTQHVM-ADTGKRRLSQTFC--GSYAYAPPEILRGIAYDGT------LADIWSLGVVLYTMVSASLPFDDTNLKVLLEQVS 278
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Nematostella
Match: EDO37951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE61]) HSP 1 Score: 76.2554 bits (186), Expect = 6.336e-15 Identity = 72/274 (26.28%), Postives = 123/274 (44.89%), Query Frame = 1
Query: 181 IDDKIAQGGYGTVYKAHS--FHKQYALKKLCVNN--EDKLLNCI-REIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQF--TTLAYRSPE-MADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQ----FTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQL 966
+ D + +G Y V KA+S + + A+K +C ED L + REI +L+ + Y+ ++ I T ++I+T+ + ++ + TE + I+ V H+ S I+HRDLK EN+L+ + ++ DFG A R C + + ++S + AY +PE + + YD AD+W++GV++Y + LPF DS L L Q T SD +++ +LT R + QL
Sbjct: 54 LGDVLGKGSYAVVRKANSKRYKRDVAIKIICKKKAPEDFLTKFLPREIKVLKKIKNTYVTTLLEVIETNT-----RMYIITDLAENG---DLLEYIRTHGALTEKASRRLFRQITAGV---HYIHSQDIVHRDLKCENLLLDKDLNIIISDFGFA-----RDC-LTTATGKKKLSHTYCGSYAYAAPEILKGIAYD------ATLADVWSMGVILYTMLCGRLPFDDSNLRSLLQQVHKRVTFSSRVKLSDAAKAIIHKMLTWNLPERITVEQL 304
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Nematostella
Match: EDO40703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6E0]) HSP 1 Score: 73.9442 bits (180), Expect = 2.112e-14 Identity = 63/227 (27.75%), Postives = 108/227 (47.58%), Query Frame = 1
Query: 193 IAQGGYGTVYKAHSFHK--QYALKKLCVNNED------KLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYP-----MRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMA-DLYYDGGEHVIGRKADIWALGVLMYNICFFSLPF 831
+ +G +G V +A ++A+K VN E KLL RE+ I++ ++ E+++H + IY+T ++ V L + + + M + FTE + ++ + AVA LH I+HRDLK+EN+L+ +P + + DFG + +K D Q S T Y +PE+ DL Y ++ D+W++GV+MY + PF
Sbjct: 33 LGRGSFGVVNEAKHIETGTRWAIK--AVNKEKAGSSAVKLLE--REVMIMKKIYHEHLIHLEE--IYETSKRMYLVMELCD------AGGLDKMLERKKRFTEKETWTVIKQLVSAVAYLHDL---DIVHRDLKLENILLSHPTGNELLNVKITDFGLSIVKGGVGSDSMMQ------SVCGTPMYMAPEVIDDLGYS-------QQCDVWSIGVIMYTLFTGRPPF 231
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Medaka
Match: bmp2k (BMP2 inducible kinase [Source:NCBI gene;Acc:101161412]) HSP 1 Score: 229.95 bits (585), Expect = 1.632e-65 Identity = 137/336 (40.77%), Postives = 198/336 (58.93%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHK-QYALKKLCVNNEDKLLNCIREIFILRNVHC-EYILHFVDSIIYQTDSDIFEVFILTNF-YPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
V +++ +A+GG+ V+ A + + ALK++ VNN L C REI I++ + + I+ ++DS I +++EV IL F + +M + F+E++VL I + EAVA LH TPIIHRDLKVEN+L+ YVLCDFGSAT K + P ++DEI ++TTL+YR+PEM +LY G I KADIWALG L+Y +CFF+LPFG+S ++I G F VPD+ +S L ++ Y+L P+ E RP+IYQ++ F + + NPV N S P +L P+ SE + + + S +PT ETSI PR RPK
Sbjct: 38 VTVEELVAEGGFSVVFMARTHSGVRCALKRMYVNNVQDLNVCKREITIMKELSGHKNIVTYLDSTISSFSDNVWEVLILMEFCKAGQVVKQMNQRLNVG--FSEAEVLHIFCDTCEAVARLHQ-CKTPIIHRDLKVENILLNDQGNYVLCDFGSATHKVLLPHKDGVTAVEDEIKKYTTLSYRAPEMINLYAGTG---ITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFIVPDNSKFSCRLHCLIRYMLEPDLEKRPDIYQVSHFAFKLAGRENPVPNLCSSAIP--TSLPEPLTASEVAAKKNLTKARITDSVVPT---ETSIAPRQRPK 362
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Medaka
Match: aak1a (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:101173792]) HSP 1 Score: 232.261 bits (591), Expect = 7.560e-65 Identity = 145/344 (42.15%), Postives = 209/344 (60.76%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVY--KAHSFHKQYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
V +++ IA+GG+ V+ + H H+ ALK++ VNNE L C EI I+R+ V + I+ F+DS I S D++EV IL +F ++ ++T F+E++VL I + EAVA LHH TPIIHRDLKVEN+L+ YVLCDFGSAT + P + +++EI ++TTL+YR+PEM +LY GGE I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ Y+L P P+ RP+IYQ++ F + + PV N S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 46 VTVEEIIAEGGFAIVFLVRTHQGHR-CALKRMYVNNEHDLQICKLEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFSEAEVLQIFCDTCEAVARLHH-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQEEGVAAVEEEIKKYTTLSYRAPEMVNLY--GGE-AITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQEMHCLIRYMLEPHPDIRPDIYQVSYFAFKLARRECPVPNLHNSPIP--AKLPEPIRASE-AVAKKSQTKARLTDPVPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Medaka
Match: aak1a (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:101173792]) HSP 1 Score: 232.261 bits (591), Expect = 7.560e-65 Identity = 145/344 (42.15%), Postives = 209/344 (60.76%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVY--KAHSFHKQYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
V +++ IA+GG+ V+ + H H+ ALK++ VNNE L C EI I+R+ V + I+ F+DS I S D++EV IL +F ++ ++T F+E++VL I + EAVA LHH TPIIHRDLKVEN+L+ YVLCDFGSAT + P + +++EI ++TTL+YR+PEM +LY GGE I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ Y+L P P+ RP+IYQ++ F + + PV N S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 46 VTVEEIIAEGGFAIVFLVRTHQGHR-CALKRMYVNNEHDLQICKLEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFSEAEVLQIFCDTCEAVARLHH-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQEEGVAAVEEEIKKYTTLSYRAPEMVNLY--GGE-AITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQEMHCLIRYMLEPHPDIRPDIYQVSYFAFKLARRECPVPNLHNSPIP--AKLPEPIRASE-AVAKKSQTKARLTDPVPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Medaka
Match: aak1a (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:101173792]) HSP 1 Score: 233.417 bits (594), Expect = 1.399e-64 Identity = 145/344 (42.15%), Postives = 209/344 (60.76%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVY--KAHSFHKQYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
V +++ IA+GG+ V+ + H H+ ALK++ VNNE L C EI I+R+ V + I+ F+DS I S D++EV IL +F ++ ++T F+E++VL I + EAVA LHH TPIIHRDLKVEN+L+ YVLCDFGSAT + P + +++EI ++TTL+YR+PEM +LY GGE I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ Y+L P P+ RP+IYQ++ F + + PV N S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 46 VTVEEIIAEGGFAIVFLVRTHQGHR-CALKRMYVNNEHDLQICKLEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFSEAEVLQIFCDTCEAVARLHH-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQEEGVAAVEEEIKKYTTLSYRAPEMVNLY--GGE-AITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQEMHCLIRYMLEPHPDIRPDIYQVSYFAFKLARRECPVPNLHNSPIP--AKLPEPIRASE-AVAKKSQTKARLTDPVPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Medaka
Match: aak1a (AP2-associated protein kinase 1 [Source:NCBI gene;Acc:101173792]) HSP 1 Score: 233.417 bits (594), Expect = 1.751e-64 Identity = 145/344 (42.15%), Postives = 209/344 (60.76%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVY--KAHSFHKQYALKKLCVNNEDKLLNCIREIFILRN-VHCEYILHFVDSIIYQTDS-DIFEVFILTNFYPDN-----LSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPG 1179
V +++ IA+GG+ V+ + H H+ ALK++ VNNE L C EI I+R+ V + I+ F+DS I S D++EV IL +F ++ ++T F+E++VL I + EAVA LHH TPIIHRDLKVEN+L+ YVLCDFGSAT + P + +++EI ++TTL+YR+PEM +LY GGE I KADIWALG L+Y +CFF+LPFG+S ++I G FT+PD+ YS ++ ++ Y+L P P+ RP+IYQ++ F + + PV N S P L P++ SE ++ ++ K +PT ETSI PR RPK G
Sbjct: 46 VTVEEIIAEGGFAIVFLVRTHQGHR-CALKRMYVNNEHDLQICKLEIQIMRDLVGNKNIVGFLDSSITAVGSGDVWEVLILMDFCRGGQVVNLMNQRLQT------GFSEAEVLQIFCDTCEAVARLHH-CKTPIIHRDLKVENILLHDRGHYVLCDFGSATNRFQNPQEEGVAAVEEEIKKYTTLSYRAPEMVNLY--GGE-AITTKADIWALGCLLYKLCFFTLPFGESQVAICDGSFTIPDNSRYSQEMHCLIRYMLEPHPDIRPDIYQVSYFAFKLARRECPVPNLHNSPIP--AKLPEPIRASE-AVAKKSQTKARLTDPVPT--TETSIAPRQRPKAG 373
BLAST of AP2-associated protein kinase 1-like Protein vs. Planmine SMEST
Match: SMESG000051989.1 (SMESG000051989.1) HSP 1 Score: 1150.96 bits (2976), Expect = 0.000e+0 Identity = 605/607 (99.67%), Postives = 606/607 (99.84%), Query Frame = 1
Query: 61 MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPGGKLQNYNNCHNTVQKPXXXXXXXXXXXXXXPDLLDFESQLEIESNNFETANQFSKTKSVDKLEFENANQTNLMDFSSPIDDKIKQLINTPKSHSLSKNFGTHGSKEHYNVYEMISHSYQNVSSXXXXXXXXXXXXXXXXXXXXPFMNNCSIXXXXXXXXXXHCNVLNFGTPQNFNTVGPTVHRRNVSDPSQWFQSPNVPNQVSNTASSNILQPQKLPMKMKPTNVLDEFDPLTK 1881
MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSI LKYESVVIDDKIAQGGYGTVYKAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNAL+LPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPGGKLQNYNNCHNTVQKPNISEEKSNNINSQNPDLLDFESQLEIESNNFETANQFSKTKSVDKLEFENANQTNLMDFSSPIDDKIKQLINTPKSHSLSKNFGTHGSKEHYNVYEMISHSYQNVSSAQQFRYNNYNYNNNQFNAARPFMNNCSIPNNNPFFMNNHCNVLNFGTPQNFNTVGPTVHRRNVSDPSQWFQSPNVPNQVSNTASSNILQPQKLPMKMKPTNVLDEFDPLTK
Sbjct: 1 MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSIALKYESVVIDDKIAQGGYGTVYKAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPDHCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALNLPMKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPKPGGKLQNYNNCHNTVQKPNISEEKSNNINSQNPDLLDFESQLEIESNNFETANQFSKTKSVDKLEFENANQTNLMDFSSPIDDKIKQLINTPKSHSLSKNFGTHGSKEHYNVYEMISHSYQNVSSAQQFRYNNYNYNNNQFNAARPFMNNCSIPNNNPFFMNNHCNVLNFGTPQNFNTVGPTVHRRNVSDPSQWFQSPNVPNQVSNTASSNILQPQKLPMKMKPTNVLDEFDPLTK 607
BLAST of AP2-associated protein kinase 1-like Protein vs. Planmine SMEST
Match: SMESG000071701.1 (SMESG000071701.1) HSP 1 Score: 270.781 bits (691), Expect = 7.812e-81 Identity = 150/353 (42.49%), Postives = 219/353 (62.04%), Query Frame = 1
Query: 175 VVIDDKIAQGGYGTVYKAHSFHKQ-YALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYPDNLSSEMKTMCSSSQCFTESDVLLIMTNISEAVACLHHFTSTPIIHRDLKVENVLIGYPMRYVLCDFGSATLKEVRPCDVNRQDLQDEISQFTTLAYRSPEMADLYYDGGEHVIGRKADIWALGVLMYNICFFSLPFGDSVLSILSGQFTVPD-HCPYSDDLLKVLNYILTPEPESRPNIYQLASVLFSMTSKSNPVQNCEKSREPDLNALSLP------------------MKESEFKMSNTNRQKKNSKSSMPTQPVETSIIPRNRPK 1173
VV+++ IA+GG+G V+K S +ALK+LCVNN L C REI I+ ++ + IL +DS I + +DIFEV +L + P N++ MK+ +Q +E+ ++ I+ +I EAVA LH + TP+IHRDLKVEN+LI YVLCDFGSAT +++ P + ++EIS++TTLAYRSPEM L G +I K+DIWALG L+Y +C+F+LPF D VL+I SG+FT+P YSD +LK++ Y+LT P RP+IYQ++ + FSM + NP+QN +K + P + L LP E+ + ++N K S S+ ++ + TSI PR RP+
Sbjct: 65 VVVEEIIAEGGFGLVFKVRSQTDHIFALKRLCVNNRIDLKVCKREITIMSSLTHKNILSLIDSQINEQQNDIFEVLMLLAYCPKNVAHLMKSKQKVNQHLSENMIIKILCDIIEAVARLH-YCQTPVIHRDLKVENILIDERNNYVLCDFGSATARQIIPTEYGIGKTEEEISKYTTLAYRSPEMVQL----GSDIINCKSDIWALGCLLYYLCYFTLPFADRVLAIQSGKFTIPKIDVVYSDKILKLIQYMLTVNPADRPSIYQVSVLAFSMANGKNPIQNLDKEKVPQWDELPLPNSNHTPRKAVPHIKGDQLTNETPKTLLSSNANKVKSVSNQ-SKSISTSINPRIRPR 411
BLAST of AP2-associated protein kinase 1-like Protein vs. Planmine SMEST
Match: SMESG000036159.1 (SMESG000036159.1) HSP 1 Score: 168.318 bits (425), Expect = 8.857e-49 Identity = 86/120 (71.67%), Postives = 92/120 (76.67%), Query Frame = 1
Query: 61 MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYP 420
MNRTIY VIE EDI RN+ ESVV+DDKIAQGG GTV+KAHSFH+QYAL KLCVNNEDKLLNCIR+IFI RNV CEYILH VDSII QTDSDIFE FI+TNFYP
Sbjct: 1 MNRTIYGVIEKEDICRNID-----------------ESVVMDDKIAQGGCGTVFKAHSFHEQYALTKLCVNNEDKLLNCIRKIFIHRNVRCEYILHLVDSIIDQTDSDIFEAFIMTNFYP 103
BLAST of AP2-associated protein kinase 1-like Protein vs. Planmine SMEST
Match: SMESG000062682.1 (SMESG000062682.1) HSP 1 Score: 167.162 bits (422), Expect = 1.968e-48 Identity = 84/120 (70.00%), Postives = 92/120 (76.67%), Query Frame = 1
Query: 61 MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYP 420
MNR Y VIENEDI RN+ ESVV+D+KI QGG GTV+KAHSFH+QYAL KLCVNNEDKLLNCIR+IFILRNVHCEYILH VDSII QTDSD+FE FI+TNFYP
Sbjct: 1 MNRKTYGVIENEDICRNID-----------------ESVVMDNKITQGGCGTVFKAHSFHEQYALTKLCVNNEDKLLNCIRKIFILRNVHCEYILHLVDSIIDQTDSDVFESFIMTNFYP 103
BLAST of AP2-associated protein kinase 1-like Protein vs. Planmine SMEST
Match: SMESG000004784.1 (SMESG000004784.1) HSP 1 Score: 166.007 bits (419), Expect = 7.976e-48 Identity = 85/120 (70.83%), Postives = 92/120 (76.67%), Query Frame = 1
Query: 61 MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYGTVYKAHSFHKQYALKKLCVNNEDKLLNCIREIFILRNVHCEYILHFVDSIIYQTDSDIFEVFILTNFYP 420
MNRTIY VIENEDI RN+ ESVV+DDKIAQGG GTV+KAHSFH+QYAL KL VNNE+KLLNCIR+IFI RNV CEYILH VDSII QTDSDIFE FI+TNFYP
Sbjct: 1 MNRTIYGVIENEDICRNID-----------------ESVVMDDKIAQGGCGTVFKAHSFHQQYALTKLFVNNEEKLLNCIRKIFICRNVRCEYILHLVDSIIDQTDSDIFEAFIMTNFYP 103 The following BLAST results are available for this feature:
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of AP2-associated protein kinase 1-like Protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30011581 ID=SMED30011581|Name=AP2-associated protein kinase 1-like Protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2311bpback to top protein sequence of SMED30011581-orf-1 >SMED30011581-orf-1 ID=SMED30011581-orf-1|Name=SMED30011581-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=608bp MNRTIYRVIENEDIYRNVGYYNCTVSKQSKSITLKYESVVIDDKIAQGGYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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