HECT and RLD domain containing E3 ubiquitin protein ligase 2

Overview


Name	HECT and RLD domain containing E3 ubiquitin protein ligase 2
Smed ID	SMED30011576
Length (bp)	15623

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of HECT and RLD domain containing E3 ubiquitin protein ligase 2 (SMED30011576) t-SNE clustered cells

Violin plots show distribution of expression levels for HECT and RLD domain containing E3 ubiquitin protein ligase 2 (SMED30011576) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HECT and RLD domain containing E3 ubiquitin protein ligase 2 (SMED30011576) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30011576

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30011576	SMESG000054104.1 SMESG000017493.1 SMESG000016095.1 SMESG000014571.1	dd_Smed_v4_3885_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30011576	SMESG000054104.1 SMESG000017493.1 SMESG000016095.1 SMESG000014571.1	dd_Smed_v4_3885_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30011576	SMESG000054104.1 SMESG000017493.1 SMESG000016095.1 SMESG000014571.1	dd_Smed_v4_3885_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011576	SMESG000054105.1 SMESG000072701.1 SMESG000056240.1 SMESG000017493.1 SMESG000016095.1 SMESG000014571.1 SMESG000007988.1 SMESG000054104.1	Contig18224	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011576	SMESG000054105.1 SMESG000072701.1 SMESG000056240.1 SMESG000017493.1 SMESG000016095.1 SMESG000014571.1 SMESG000007988.1 SMESG000054104.1	Contig18224	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011576	SMESG000074552.1 SMESG000072701.1 SMESG000070601.1 SMESG000054104.1 SMESG000046807.1 SMESG000045951.1 SMESG000037636.1 SMESG000031066.1 SMESG000022931.1 SMESG000014571.1 SMESG000005372.1	Contig30920	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011576	SMESG000074552.1 SMESG000072701.1 SMESG000070601.1 SMESG000054104.1 SMESG000046807.1 SMESG000045951.1 SMESG000037636.1 SMESG000031066.1 SMESG000022931.1 SMESG000014571.1 SMESG000005372.1	Contig30920	newmark_ests	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30011576	SMESG000074552.1 SMESG000072701.1 SMESG000070601.1 SMESG000054104.1 SMESG000046807.1 SMESG000045951.1 SMESG000037636.1 SMESG000031066.1 SMESG000022931.1 SMESG000014571.1 SMESG000005372.1	Contig30920	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30011576	SMESG000074552.1 SMESG000072701.1 SMESG000070601.1 SMESG000054104.1 SMESG000046807.1 SMESG000045951.1 SMESG000037636.1 SMESG000031066.1 SMESG000022931.1 SMESG000014571.1 SMESG000005372.1	Contig30920	newmark_ests	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30011576	SMESG000054104.1 SMESG000017493.1 SMESG000016095.1 SMESG000014571.1	dd_Smed_v4_3885_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
parapharyngeal region	SMED30011576	SMESG000054104.1	DN306131	ncbi_smed_ests	PMID:25956527 Henderson et al., 2015
neoblast	SMED30011576	SMESG000054104.1	DN306131	ncbi_smed_ests	PMID:25956527 Henderson et al., 2015
parenchymal cell	SMED30011576	SMESG000054104.1	DN306131	ncbi_smed_ests	PMID:25956527 Henderson et al., 2015

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Homology

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 1001.12 bits (2587), Expect = 0.000e+0
Identity = 597/1325 (45.06%), Postives = 804/1325 (60.68%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+       ++  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +++ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ V+ +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+       S  G      PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++LSP A    ++  F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3612 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKELLSDRC---------VLSCPSMDLVTCLLDFRLNLASNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRKLLTT-------EFGQSININRLLGENDGETRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSENMDVLHESHDIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHLSELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-------SSFG------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLSPAARAPVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4802

HSP 2 Score: 486.878 bits (1252), Expect = 1.821e-136
Identity = 270/519 (52.02%), Postives = 344/519 (66.28%), Query Frame = 2

Query: 9323 NSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDV-FDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLV 10876
            N   ED   NS +L        +++   + I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA  +    D +     N+    + SK        N  +L+ ++  L G   +   +  +   LQ++ AR+ V
Sbjct: 2930 NEEEEDEKGNSGSLIRKKAAGLESA---ATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGASYLGVPSDADSSAASNKISGASNSK-------PNRPSLAKILLSLDGNLAKQQALSHILTALQIMYARDAV 3413

HSP 3 Score: 374.4 bits (960), Expect = 1.749e-102
Identity = 196/393 (49.87%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++VV +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 3954 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 4341

HSP 4 Score: 358.992 bits (920), Expect = 8.375e-98
Identity = 211/396 (53.28%), Postives = 276/396 (69.70%), Query Frame = 2

Query: 12407 KKCWPIDSASGL--EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            KK   ++SA+ +  +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2946 KKAAGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3327

HSP 5 Score: 281.952 bits (720), Expect = 1.961e-74
Identity = 160/377 (42.44%), Postives = 224/377 (59.42%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L    I+   K    ++R G+VY    +S+                + P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +V+++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        P  +  L    I  +ACG + S AW++
Sbjct:  422 LQEVIGWGL-----IGWKYYANVIGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNSD---------------TLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSS 778

HSP 6 Score: 262.307 bits (669), Expect = 1.408e-68
Identity = 170/384 (44.27%), Postives = 221/384 (57.55%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L+ L   QI   E+   I+S +GRVY   + ++             P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   V+KV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  417 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNSD----------TLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSSCS 780

HSP 7 Score: 136.732 bits (343), Expect = 1.178e-30
Identity = 91/264 (34.47%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + +V +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 4059 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 4315

HSP 8 Score: 118.242 bits (295), Expect = 5.038e-25
Identity = 91/265 (34.34%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  ++V +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3951 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4215

HSP 9 Score: 106.686 bits (265), Expect = 1.517e-21
Identity = 170/685 (24.82%), Postives = 281/685 (41.02%), Query Frame = 2

Query: 4667 IIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAYKAALMLKK---PKK--STDYWQIVYN---------------FVMKKFAGKIRQNKSAAIKLVDNSENIREF----------------CGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCD-KVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLLVNDQK-----IESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSD--SRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAG---QLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTL-ITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKLI 6559
            +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RW+ IA K     +K   PKK  STD  + + N                 + K    I+  K     L+     + ++                   I +F L +E +D++K+R  +L +    +++ + +  ILK     L     LLP VQ ++   FC  +  I +  + G   E + D LK  + +  FN + L        T   L   ++Q +R  L+    K     I+ +    + N       +G    A+  L + + L  T+    +   LLL +G+L L QT LR        LI   C +        +   S  +  ET K  +   L  S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L         E P+                   A +   ++++T  +S+ +     + P+A +F S  N    L L SAG   ++MQ+ + + L                      LL  L+   +   +   N   + +Y+EQ   WC   F+ ++ +T       +S  WI L +K  E     ++T ++  QIL + +L+ ++
Sbjct: 1491 LIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIMSKFKL-----------LSSLP---RWRRIAQKIIRERRKKRVPKKPESTDDEEKIGNEESDLEEACILPHSPINVDKRPIAIKSPKDKWQPLLSTVTGVHKYKWLKQNVQGLYPQSPLLSTIAEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILK-----LASKNFLLPSVQYAM---FCGWQRLIPEGIDIG---EPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNVLMDASAKFKELGIQPVPLQTITNENPSGPSLGTIPQARFLLVMLSML--TLQHGANNLDLLLNSGMLALTQTALR--------LIGPSCDNVEEDMNASAQGASATVLEETRKETAPVQLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLA--------ELPA-------------------AAQPSAEDSDTEDDSEAEQTERNIHPTAMMFTSTINLLQTLCL-SAGVHAEIMQSEATKTL--------------------CGLLRMLVESGTTDKTSSPN---RLVYREQHRSWCTLGFVRSIALTPQVCGALSSPQWITLLMKVVEGHAPFTAT-SLQRQILAVHLLQAVL 2081

HSP 10 Score: 102.834 bits (255), Expect = 2.172e-20
Identity = 64/209 (30.62%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ L K G VY+W K
Sbjct:  480 DTLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGK 683

HSP 11 Score: 97.0561 bits (240), Expect = 1.101e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4042 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4271

HSP 12 Score: 84.7297 bits (208), Expect = 6.311e-15
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3058 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3231

HSP 13 Score: 84.3445 bits (207), Expect = 8.530e-15
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  604 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 740

HSP 14 Score: 83.1889 bits (204), Expect = 2.106e-14
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  625 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGL 758

HSP 15 Score: 82.0333 bits (201), Expect = 4.664e-14
Identity = 61/205 (29.76%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  VVK  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  571 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACG 769

HSP 16 Score: 80.4925 bits (197), Expect = 1.123e-13
Identity = 47/136 (34.56%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RV+D+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4143 HRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4274

HSP 17 Score: 76.6406 bits (187), Expect = 1.982e-12
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3100 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3282

HSP 18 Score: 76.2554 bits (186), Expect = 2.343e-12
Identity = 44/136 (32.35%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+DV A    +H   VT AG +Y+WG    G+LG  D++D+ +P +++   + H +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L G+ V ++      S+ L+  GA++TWG
Sbjct: 4093 VVDVAAG--GAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEAL-QGH-RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGLGVVKVECGSQFSVALTKSGAVYTWG 4222

HSP 19 Score: 75.8702 bits (185), Expect = 2.937e-12
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct: 3035 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3281

HSP 20 Score: 73.9442 bits (180), Expect = 1.208e-11
Identity = 68/241 (28.22%), Postives = 106/241 (43.98%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVSMISK----------------GDGEFYFLDKSG 2293
            A T   +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+  S+                GDG+F  L + G
Sbjct: 2954 AATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3189

HSP 21 Score: 63.1586 bits (152), Expect = 1.957e-8
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 3997 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 4116

HSP 22 Score: 57.3806 bits (137), Expect = 1.191e-6
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3211 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3325

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 999.579 bits (2583), Expect = 0.000e+0
Identity = 597/1325 (45.06%), Postives = 804/1325 (60.68%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+       ++  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +++ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ V+ +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+       S  G      PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++LSP A    ++  F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct:  859 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKELLSDRC---------VLSCPSMDLVTCLLDFRLNLASNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRKLLTT-------EFGQSININRLLGENDGETRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSENMDVLHESHDIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHLSELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-------SSFG------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLSPAARAPVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 2049

HSP 2 Score: 485.337 bits (1248), Expect = 8.314e-138
Identity = 270/519 (52.02%), Postives = 344/519 (66.28%), Query Frame = 2

Query: 9323 NSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDV-FDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLV 10876
            N   ED   NS +L        +++   + I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA  +    D +     N+    + SK        N  +L+ ++  L G   +   +  +   LQ++ AR+ V
Sbjct:  177 NEEEEDEKGNSGSLIRKKAAGLESA---ATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGASYLGVPSDADSSAASNKISGASNSK-------PNRPSLAKILLSLDGNLAKQQALSHILTALQIMYARDAV 660

HSP 3 Score: 372.859 bits (956), Expect = 1.197e-102
Identity = 196/393 (49.87%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++VV +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 1201 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 1588

HSP 4 Score: 357.066 bits (915), Expect = 1.102e-97
Identity = 211/396 (53.28%), Postives = 276/396 (69.70%), Query Frame = 2

Query: 12407 KKCWPIDSASGL--EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            KK   ++SA+ +  +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct:  193 KKAAGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 574

HSP 5 Score: 135.961 bits (341), Expect = 1.840e-30
Identity = 91/264 (34.47%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + +V +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 1306 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 1562

HSP 6 Score: 117.087 bits (292), Expect = 8.461e-25
Identity = 91/265 (34.34%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  ++V +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 1198 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 1462

HSP 7 Score: 94.3597 bits (233), Expect = 7.069e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWGS---------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSV-LLKSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 1289 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 1518

HSP 8 Score: 85.1149 bits (209), Expect = 4.193e-15
Identity = 59/181 (32.60%), Postives = 89/181 (49.17%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWGS-TFDNCRRHLS---NWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S   N    IE    +    + QI+        L KSG V+TW K
Sbjct:  305 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQ---GVCQIECGAQFSLALTKSGVVWTWGK 478

HSP 9 Score: 82.0333 bits (201), Expect = 3.388e-14
Identity = 47/136 (34.56%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RV+D+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 1390 HRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 1521

HSP 10 Score: 76.6406 bits (187), Expect = 1.690e-12
Identity = 44/136 (32.35%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+DV A    +H   VT AG +Y+WG    G+LG  D++D+ +P +++   + H +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L G+ V ++      S+ L+  GA++TWG
Sbjct: 1340 VVDVAAG--GAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEAL-QGH-RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGLGVVKVECGSQFSVALTKSGAVYTWG 1469

HSP 11 Score: 75.0998 bits (183), Expect = 4.625e-12
Identity = 44/127 (34.65%), Postives = 67/127 (52.76%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct:  355 SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWG 477

HSP 12 Score: 74.7146 bits (182), Expect = 6.578e-12
Identity = 55/198 (27.78%), Postives = 93/198 (46.97%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQ-VKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+   R + Q V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct:  347 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIE---RLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 529

HSP 13 Score: 73.559 bits (179), Expect = 1.266e-11
Identity = 55/175 (31.43%), Postives = 81/175 (46.29%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVD--GHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            A T   +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW
Sbjct:  201 AATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSA--LNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTW 370

HSP 14 Score: 64.3142 bits (155), Expect = 9.322e-9
Identity = 41/122 (33.61%), Postives = 66/122 (54.10%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++     ++   V  G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 1244 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 1363

HSP 15 Score: 56.6102 bits (135), Expect = 2.016e-6
Identity = 25/60 (41.67%), Postives = 37/60 (61.67%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct:  515 HCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 572

HSP 16 Score: 55.0694 bits (131), Expect = 5.471e-6
Identity = 40/126 (31.75%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VY+ G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  L++ G ++TWG
Sbjct:  248 SKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAALTSSGELYTWG 371

HSP 17 Score: 54.299 bits (129), Expect = 8.391e-6
Identity = 35/116 (30.17%), Postives = 56/116 (48.28%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLS 1981
            S   +A+T++G VY+WG     +LG G     +RP  +        +V  +A G  H +  T+ G++Y+ G N  GQLG G       P R+ A+ L G  V ++A     ++  S
Sbjct: 1453 SQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQ--GKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRP-RLVAA-LQGKKVNRVACGSAHTLAWS 1564

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 483.797 bits (1244), Expect = 8.976e-141
Identity = 270/519 (52.02%), Postives = 344/519 (66.28%), Query Frame = 2

Query: 9323 NSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDV-FDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLV 10876
            N   ED   NS +L        +++   + I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA  +    D +     N+    + SK        N  +L+ ++  L G   +   +  +   LQ++ AR+ V
Sbjct:  167 NEEEEDEKGNSGSLIRKKAAGLESA---ATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGASYLGVPSDADSSAASNKISGASNSK-------PNRPSLAKILLSLDGNLAKQQALSHILTALQIMYARDAV 650

HSP 2 Score: 424.091 bits (1089), Expect = 5.098e-121
Identity = 273/672 (40.62%), Postives = 389/672 (57.89%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIK 13231
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+       ++  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +++ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ V+ +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMK+  + GA +++
Sbjct:  849 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKELLSDRC---------VLSCPSMDLVTCLLDFRLNLASNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRKLLTT-------EFGQSININRLLGENDGETRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSENMDVLHESHDIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKVRFIHGATMMR 1438

HSP 3 Score: 354.369 bits (908), Expect = 2.718e-98
Identity = 211/396 (53.28%), Postives = 276/396 (69.70%), Query Frame = 2

Query: 12407 KKCWPIDSASGL--EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            KK   ++SA+ +  +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct:  183 KKAAGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 564

HSP 4 Score: 212.616 bits (540), Expect = 7.077e-54
Identity = 124/243 (51.03%), Postives = 160/243 (65.84%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKI 10153
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++VV +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P K+
Sbjct: 1191 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKV 1428

HSP 5 Score: 106.301 bits (264), Expect = 1.410e-21
Identity = 89/270 (32.96%), Postives = 132/270 (48.89%), Query Frame = 2

Query: 12740 LALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINR 13543
            L+   +G +Y WG     +LG       G  V  PT  ++L     + +  G     A++  G+LY  G G  GRLG G  +    P ++E+++   +  VA  SG    L ++   +          V+SWG+ + GKLG G    C  P  IE+L G  V+ V  G   S  +TA+G++YTWGKG Y RLGH       KP+ V  L   +++D+ACGS     +C T+D  V+SWGD D G+LG G +     P  +  + G  + R
Sbjct: 1183 LSAGGSGTIYGWGHNHRGQLG----GIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGE----------VYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKVRFIHGATMMR 1438

HSP 6 Score: 103.99 bits (258), Expect = 7.097e-21
Identity = 80/230 (34.78%), Postives = 117/230 (50.87%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNG 10432
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  ++V +A G+     L +TD   V+SWGD D+G+ G G
Sbjct: 1188 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRG 1417

HSP 7 Score: 93.5893 bits (231), Expect = 1.090e-17
Identity = 66/218 (30.28%), Postives = 110/218 (50.46%), Query Frame = 2

Query: 9908 GHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTL-ALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMS--LSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF 10552
            G +Y WG    G+LG  + A    P   ++L   + VQ+  G    QTL A+T+D  +++ G G  G+LG GG+     P  +E +       + +  G +   AL+  G+V++WG+ +  +LGHG       P  IE L+  ++V +A G  H   VT  G +Y+WG   +G+ G+      ++P LV AL  +++  +ACGS  +     +D D+ 
Sbjct: 1189 GTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGE---QTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTV 1403

HSP 8 Score: 93.2041 bits (230), Expect = 1.579e-17
Identity = 66/223 (29.60%), Postives = 110/223 (49.33%), Query Frame = 2

Query: 12932 LYTWGKGRYGRLGHGNGDDQPFPKIVEAL---RGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGV--IKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGS--AHTLAWT 13579
            +Y WG    G+LG   G     P   EAL   R   +IG                E +   +  +  +++ G G  G+LG GG +    P  +E+++   +  + V+ G +  L L++ GEVY+WG+ +  +LGHG+ +   +P  +  L   +++DVA G  H  C T  G++Y+WG    G+LG   +    +P+++E+L G  +  +ACGS  A TL  T
Sbjct: 1191 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIG---------------GEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLT 1398

HSP 9 Score: 87.4261 bits (215), Expect = 8.092e-16
Identity = 49/133 (36.84%), Postives = 74/133 (55.64%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG 2008
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG
Sbjct: 1279 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVVDIACGSGDAQTLCLTDDDTVWSWG 1407

HSP 10 Score: 83.5741 bits (205), Expect = 1.107e-14
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct:  295 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 468

HSP 11 Score: 78.1814 bits (191), Expect = 4.748e-13
Identity = 45/147 (30.61%), Postives = 70/147 (47.62%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVV 9862
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + +V +A  SG    + LT +   +SWG+GD GKLG         P K+++  G  ++
Sbjct: 1296 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQ-----LKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKVRFIHGATMM 1437

HSP 12 Score: 75.0998 bits (183), Expect = 4.959e-12
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct:  337 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 519

HSP 13 Score: 74.3294 bits (181), Expect = 7.000e-12
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct:  272 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 518

HSP 14 Score: 72.7886 bits (177), Expect = 2.512e-11
Identity = 68/241 (28.22%), Postives = 106/241 (43.98%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVSMISK----------------GDGEFYFLDKSG 2293
            A T   +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+  S+                GDG+F  L + G
Sbjct:  191 AATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 426

HSP 15 Score: 62.003 bits (149), Expect = 3.964e-8
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 1234 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 1353

HSP 16 Score: 59.3066 bits (142), Expect = 2.763e-7
Identity = 33/103 (32.04%), Postives = 57/103 (55.34%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRI 1909
            V+DV A    +H   VT AG +Y+WG    G+LG  D++D+ +P +++   + H +V  +AC  G+  +L LT    ++S G    G+LG G      +P+++
Sbjct: 1330 VVDVAAG--GAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEAL-QGH-RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKV 1428

HSP 17 Score: 56.6102 bits (135), Expect = 1.909e-6
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct:  448 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 562

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
Match: HERC1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:HGNC Symbol;Acc:HGNC:4867])

HSP 1 Score: 445.277 bits (1144), Expect = 7.070e-124
Identity = 343/1101 (31.15%), Postives = 542/1101 (49.23%), Query Frame = 2

Query: 11966 INDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSI---------------SPVS-TADEWAWFRNYCLTYRTTESLITNSSLPYRF-INEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWK---KCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSL-STRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL--NRQS------------VMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYAD-KTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET----ELENLQIP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            +N    +  FL  L  ++ +Q+ +E+P V    QL +S +++ L  L+  + LD +                P S   +EWAW   +  T +  E+L   +  P  F + +       EP  +D L   +          D  ++    D QI+ W  SRP+ W    KC         +V+ WG    GQL    G  + VP      S  + +Q+I G+   F++  +G V A G G+ GRLG G+++ +    ++S L+  +V ++  + G   H +AL  +G V++WGD +  KLG        +    P  +++L   E++ ++ G  HSA ++  G+L+T+G G YGRLG GN  ++  P+ V AL GY +  VACG     TL ++ +          + VW++GDGDYGKLG G       P KI+ L G G+ KV CG+QFS+ LT  G VYT+G+     L  G   +  +P+++  L    I DVA G+ H +    +G+VY+WG N EGQLG G T     P ++  L GK + +++ G  H+ AWT           S   +L L  T P     L   S  ++  R  LL+H+++L  S+   ++L  N Q+            V  ++R +L P          +  TM   K +GP+I V R+                                G  C         K +F Q+  ++++    ++ S            LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I SP        ++D F+ +P A    +   F FLG L+G+AIRT +PL L ++ L+WK L    L   DL+  D   + +L S+  I+++    E  +  IP   +   + DGK V + I    +I +  SNR  Y++  I Y++HE D+    +R G+S ++P+PLL+L ++++LE +VCG   I +  LK +  YR V     ++ WFW  +EE +NE R LF+RFV GR+RLP   +D+  +  +++V   Y    D LP + TCFF L+LP YSS+ ++ E+L YAI+ C+SID+D+Y
Sbjct: 3844 LNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQNCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDL------EPVPEDELVFLM----------DNSKWINGMDEQIMSWATSRPEDWHLGGKC---------DVYLWGAGRHGQLAEA-GRNVMVPAAAPSFS--QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHG----NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLN--HTLAVSAD---------GSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGALREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRIST-----------------------------RGRKC---------KPIFVQIARQVVK----LNASD---------LRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPI-IPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY----DSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNY 4845

HSP 2 Score: 232.646 bits (592), Expect = 1.270e-59
Identity = 146/380 (38.42%), Postives = 211/380 (55.53%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFT-VWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLP 10558
            +Y+WG     QL  EA   V +P    + S+   V    G    F +   G V   G+ S GRLG G+  D+    +I      AL  + + ++    G   H++ALT++GE FSWG+GD GKLGH +  +   PR+I+  +G+ VV ++CG  HSA +   G L+T+G GDYGRLG G+T+ +  PE V +L  Y++ QVACG     TLA+++D + VW++GDGD+GKLG G S+    PQKI+ +    + ++ CG Q S ALT++G V+T+G+     L  G  ++   P QI  L    I  +AVGA H LA+   G VY+WG N  GQ G G   +   PTLV+ L    +  ++ G  HS AWTA  +    P
Sbjct: 3999 VYLWGAGRHGQLA-EAGRNVMVPAAAPSFSQAQQVIC--GQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVI-----SALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLN--HTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWTAPPVPPRAP 4368

HSP 3 Score: 226.098 bits (575), Expect = 1.452e-57
Identity = 154/379 (40.63%), Postives = 210/379 (55.41%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIK-YFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            ++YVWG N   QL      K+  P L  + S  D  +I  G    F ++  G V   G  S GRLG+G   + +       K+L       I KV+   G   H +A T  GE FSWG+GD GKLGH +     YP+ I+   +GK VV V+ G  HSAA+   G LYTWG GD+GRLGHGD+  R  P LVK + +  V +V+CGS  + T+AL+ D  TVWS+G GD GKLG G ++    P+ IE +    + ++  G+QSS ALT  GQV+ WG G     G      +R P  IE+L  T+IV +++G  HCLA++   +VY+WG+N  GQ G G  T  + +P  VS L    I  ++ G+SHS+AWTA   D
Sbjct:  373 EVYVWGSNSSHQLVEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTL-----KKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGEVSCGS--SHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRD 739

HSP 4 Score: 182.956 bits (463), Expect = 1.501e-44
Identity = 140/386 (36.27%), Postives = 218/386 (56.48%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKV--PVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXX-XXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV+ WG N   QL  VEG++ K+  P L    S    + I  G+   F++S DG V A G G+ GRLG+G + +  T   ++    + + KV+ + G   H LA    G V++WGD +  KLG             P L++  ++ +++  ++AG  HSAA++  GELYTWG+G +GRLGHG+ + +  P +V+ +   +V  V+CGS  + T+ ++K  D R       +VWS+G GD GKLG G  +    P  IE L+G  + KV  GSQ SL LT++G+VY WG G     G  S+    +P+ + +L   +I+DV+ G  HC+  + D EVY+WG+N  GQ G G +T   ++P+ +  L G  I +++ G++H+LAWT +
Sbjct:  373 EVYVWGSNSSHQL--VEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHG----NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGS--SHTIALSK--DGR-------TVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCG-SSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTAL 736

HSP 5 Score: 101.679 bits (252), Expect = 4.656e-20
Identity = 85/267 (31.84%), Postives = 133/267 (49.81%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGE-TFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALT 10219
            +++ WG  D  +LG   + + + P   EAL   + V +S G K    VT  GK++  G+   GRLG+G+ ++        P+R+ AL+ Y I +VA   G  H +A++ +G   +++G+GD GKLG  +    + P+KI    G  +  VACG+  S A+   GH+YT+G      L  G       P+ +  L    +  VA G+    TLAL S+  V++WG    G+LG G ++    P  +  +   NV QI  G   S A T
Sbjct: 4102 EVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKL-----PERVTALEGYQIGQVAC--GLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAE--HTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWT 4359

HSP 6 Score: 99.7525 bits (247), Expect = 1.675e-19
Identity = 96/358 (26.82%), Postives = 157/358 (43.85%), Query Frame = 2

Query: 12398 DAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEG---SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSG-LEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHG-SDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT---EDGEVYSW 13447
            +A + C  + S  G  V + G    G+LG  +    S +K      H S  +     G +      + +G V++ G G+ G+LG G++ + + P L+ G L+ K+VV   V++G +H  A+  +G +Y WG+ +  +LG             PTLVK +               A       ++++G G  G+LGHG+ +    PK++EAL+G  +  V  GS             S + L     V++WG G     G       + P  IE L    ++ V  G    L L+   EVY WG     + G G S   + KP+KV+ L+   I  ++ G+ H +  T    D +V +W
Sbjct:  409 EAGQYCTFVISTDG-SVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVV--CVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG----DSNSRNIPTLVKDISNV-GEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGS------------QSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAW 745

HSP 7 Score: 87.8113 bits (216), Expect = 7.348e-16
Identity = 56/193 (29.02%), Postives = 92/193 (47.67%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG-DIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTW--GSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW----LKYCTECNKSDDI 2197
            H  AVTE G++Y+WG    G+LG GD+  R  PT++   S     V +V+CG  H++ L++ G  ++S G    G+LGHGD    + P  I A  L G+ ++++      S+ L++ G ++ W  G+         +   PK+   +   R  I  + + DS    L     VY W    +  C + N +  I
Sbjct:  522 HSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS----NVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEA--LQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATR--IVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPI 706

HSP 8 Score: 86.2705 bits (212), Expect = 2.255e-15
Identity = 42/120 (35.00%), Postives = 74/120 (61.67%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAI 1996
             H +A+TE+G+V+SWG    GKLG G++  ++RP  I+       +V Q++CG +HS ++T  G +++ G    G+LG G+  ++ LP R+TA  L G  + Q+A   + ++ +S DG++
Sbjct: 4092 GHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQ--GEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTA--LEGYQIGQVACGLNHTLAVSADGSM 4207

HSP 9 Score: 81.6481 bits (200), Expect = 5.159e-14
Identity = 58/208 (27.88%), Postives = 106/208 (50.96%), Query Frame = 2

Query: 1409 NEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYS------SHVLAVTEAGQ-VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            + + R ++I     +  V   CG+ +    +SD  +  FTF +   ++    L N S  KL    RV  ++           +H LAV+  G  V+++G    GKLG G++  +  P  ID    C + +K+VACG + S+ LT+ G +Y+ G++ +  L  G  ++ + P +I    L GV+++ +AV    ++ L+++G ++ WGS
Sbjct: 4120 DRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKL--FTFGNG--DYGRLGLGNTSNKKL--PERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVL--CGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPV--LAGVIIEDVAVGAEHTLALASNGDVYAWGS 4317

HSP 10 Score: 80.8777 bits (198), Expect = 1.069e-13
Identity = 59/202 (29.21%), Postives = 96/202 (47.52%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC---GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG-AIFTWGSTFDNCRRHLSN---WSPK-IETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSD--DIQPEL 2209
             H LA T  G+V+SWG    GKLG G++  +K P +I    +  LQ K V C   G  HS  +T+ G++Y+ G    G+LGHGD   R++P  +     +G    +++     ++ LS DG  ++++G   +    H      + PK IE     +   I ++     +   L  +G VY W    C  C  S+   ++P+L
Sbjct:  468 GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLI----QGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVG----EVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMF---IRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKL 658

HSP 11 Score: 67.0106 bits (162), Expect = 1.414e-9
Identity = 39/117 (33.33%), Postives = 61/117 (52.14%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV----DGHQSMCLSNDGAIFTWG 2008
            VY WG    G+L +   ++   P    +FS    Q +QV CG+  + ++  +G + +CG    G+LG G+  D H+   I+A  L G +V Q+      DGH SM L+  G +F+WG
Sbjct: 3999 VYLWGAGRHGQLAEAG-RNVMVPAAAPSFS----QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISA--LQGFVVTQLVTSCGSDGH-SMALTESGEVFSWG 4107

HSP 12 Score: 66.2402 bits (160), Expect = 2.540e-9
Identity = 45/132 (34.09%), Postives = 71/132 (53.79%), Query Frame = 2

Query: 1664 GQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEE-HSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPK 2056
            G V + G  + G+LGQG++ D    T+I       +     +CG + HS+ LT+SG+++S G    G+LGHG+   +  P +I A  L G  V Q++     S  +++DG +FT+G+  D  R  L N S K
Sbjct: 4046 GTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEA--LQGEEVVQMSCGFKHSAVVTSDGKLFTFGNG-DYGRLGLGNTSNK 4174

HSP 13 Score: 58.5362 bits (140), Expect = 5.949e-7
Identity = 61/264 (23.11%), Postives = 110/264 (41.67%), Query Frame = 2

Query: 1625 NIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG------------STFDNCRRHLSNWSPKIETCVNE-YRNEIDQIQVHDSTYSVLLKSGSVYTWLKY-CTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIKRNY 2368
            +I +     V+E  +VY WG+N+S +L +G  +   +P +  +FS      + +  G+  + +++  G + +CG+   G+LG GD  ++    ++T      I  +      DGH ++  + +G +F+WG            ST    +        K+  CV+  YR+            + + + G +YTW +         D     + T++K  + NV  +S G      L K G  RT  S    D+   G G   R Y
Sbjct:  359 SIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFS----DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGH-TLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHS-----------AAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVK-DISNVGEVSCGSSHTIALSKDG--RTVWSFGGGDNGKLGHGDTNRVY 603

HSP 14 Score: 57.7658 bits (138), Expect = 8.108e-7
Identity = 35/103 (33.98%), Postives = 55/103 (53.40%), Query Frame = 2

Query: 1646 LAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV 1954
            +A+T+ G VY++G +    L +G  ++  RP  I   +   + ++ VA G EH+L L  +GD+Y+ G N  GQLG G       P  +T   L G  V+QI+ 
Sbjct: 4252 VALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLA--GVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTG--LQGKNVRQISA 4350

HSP 15 Score: 57.7658 bits (138), Expect = 9.829e-7
Identity = 47/159 (29.56%), Postives = 72/159 (45.28%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSM---CLSNDGAIFTW---------GSTFDNCRRHLSNWSPKIET 2065
            S   LA+T  GQVY+WG      LG G ++    RP +I+  +    ++  V+ G+ H L L+   ++Y+ G N MGQ G G+      PI      S L G+ ++QI+     S+    L  D  +  W          STF + R  L  +  KI +
Sbjct:  623 SQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAAT--RIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTG---PITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINS 774

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868])

HSP 1 Score: 363.229 bits (931), Expect = 1.545e-109
Identity = 195/378 (51.59%), Postives = 257/378 (67.99%), Query Frame = 2

Query: 14030 KTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPD--------KDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            K+VFGQ+  K+       S  G      PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P+        +DC++LSP A    ++  F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct:  130 KSVFGQMCAKM-------SSFG------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLSPAARAPVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 491

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Celegans
Match: herc-1 (HECT and RCC domain E3 ubiquitin ligase [Source:UniProtKB/TrEMBL;Acc:W6RY72])

HSP 1 Score: 110.153 bits (274), Expect = 2.676e-23
Identity = 84/321 (26.17%), Postives = 152/321 (47.35%), Query Frame = 2

Query: 9590 AGDSSNGRLGI---GSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLN---YPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG-HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNG-TVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
             G +  G+LG+    S   +   +I  P  ++          +V  G +H + LTK+G+ +S G   DG+LG  SR + +   YP  + +    +++ ++ G SH+ ++   G ++ WG  ++G+LG       +  P  V+ + D  +VQVA GS     +AL     V+ W        G      C+  P+ +E +S   ++++  GA+   AL+ +G V+TWG+ +   LG    +       +  +    +V  A G  H + +T  G+ +S+G +  GQ G G  V     PT VS L+ + +  +A G+ H++A
Sbjct:    8 CGHTGEGQLGVRLSESTIQVPERIIGAPNDMDG-----TAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYP--VSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEIND--IVQVASGSN--HCIALDEGGRVFVW--------GEQADGRCIHRPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIA 309

HSP 2 Score: 94.7449 bits (234), Expect = 1.670e-18
Identity = 87/325 (26.77%), Postives = 149/325 (45.85%), Query Frame = 2

Query: 12614 GFGNNGRLGIGSTES-VQTPILVSGLEEKI--VVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTT-TNSRPRIIESLTGKGINRVACGSAHTLA 13573
            G    G+LG+  +ES +Q P  + G    +      +V  G +H + L  +G +++ G   D +LG   R +    +   +   S   A+II I+AG SH+ +++  G ++ WG   +G+LG  +    Q  P+ V+ +    ++ VA GS      CI  +E  R+       VW           +        P  +E L G  +++V  G++  L L+ASG V+TWG+ +   LG          + V Q++   +++ ACG  H +  T  G  +S+G +  GQ G G      + P  +  L G  + R+A G+ HT+A
Sbjct:    9 GHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYPVSWTSS---AKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEIND--IVQVASGSNH----CIALDEGGRV------FVWG---------EQADGRCIHRPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIA 309

HSP 3 Score: 93.2041 bits (230), Expect = 4.605e-18
Identity = 98/377 (25.99%), Postives = 164/377 (43.50%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLG-GVEGSKIKVPVLC----EHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGS-TESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG-------SGDAQTLCITKNEDSRI---DLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVR-KPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESL 13522
            E+   GH   GQLG  +  S I+VP         +       +  GEQ    ++ DG++++ G   +G+LG GS TE   +   VS      +++++  +G  H +++ ++G V+AWG  E  +LG++ +        TP  V+ +   +I+ +A+G +H  A+   G ++ WG+   GR  H        P+ VE L G  ++ V  G       S         +N    +   DL P TSV                        +  ++G GV++  CG   +++LT  G  +++G     + G G     R  P  V+ L    +  +A G+ H I   + G  Y +G N  GQLG+G   T S PR  + L
Sbjct:    4 ELLGCGHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYPVSWTSSAKIIQIS--AGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQG---TPRRVQEI--NDIVQVASGSNHCIALDEGGRVFVWGEQADGRCIHR-------PEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSV----------------------QHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIAICK-GAPYPFGLNSSGQLGNGKIMTQSTPRKTDEL 343

HSP 4 Score: 89.3521 bits (220), Expect = 6.488e-17
Identity = 70/269 (26.02%), Postives = 124/269 (46.10%), Query Frame = 2

Query: 9752 GETFSWGEGDDGKLGHN-SRLKLNYPRKI----KYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG---DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWT 10531
             E    G   +G+LG   S   +  P +I        G  V  V CG  H+  +   G +++ G    G+LG G   + +  ++P  V      K++Q++ G   + T+++T D  V++WG  + G+LG          P++++   +++++Q+  G+    AL E G+V+ WG+           + I  P  +E L    IV +  GA HCLA++  G V++WG N+ G+ G   +        V  +    +   ACG +H+V  T
Sbjct:    3 AELLGCGHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYP--VSWTSSAKIIQISAGR--SHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQ--EINDIVQVASGSNHCIALDEGGRVFVWGE-------QADGRCIHRPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLT 258

HSP 5 Score: 86.6557 bits (213), Expect = 4.127e-16
Identity = 60/215 (27.91%), Postives = 102/215 (47.44%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSEL-DCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG-DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLAL 10060
            +++ WG N+  QLG E  SK         + E+ D V ++ GS     +   G+V+V G+ ++GR             I  P+ +E L    IV+V   +G RH +AL+ +G  F+WG+ + G+LG +        + +    G  VV+ ACG +H+  +   G  +++G    G+ G G     R +P  V  L    V ++A G+    T+A+
Sbjct:  114 RVFAWGSNEHGQLGME--SKFTWQGTPRRVQEINDIVQVASGSNHCIALDEGGRVFVWGEQADGR------------CIHRPEPVEQLSGVPIVRVL--AGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGA--CHTIAI 310

HSP 6 Score: 71.2478 bits (173), Expect = 2.495e-11
Identity = 36/119 (30.25%), Postives = 58/119 (48.74%), Query Frame = 2

Query: 13223 VIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            +++V  GS   + L   G V+ WG+    R  H       +PE V QL+   I+ V  G+ HC+  +  G V++WG N+ G+LG       +  + +  + G G+   ACG  HT+  T
Sbjct:  147 IVQVASGSNHCIALDEGGRVFVWGEQADGRCIH-------RPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLT 258

HSP 7 Score: 69.3218 bits (168), Expect = 8.129e-11
Identity = 47/150 (31.33%), Postives = 78/150 (52.00%), Query Frame = 2

Query: 1562 CLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHG-DVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            C+     ++  S   ++ V A   + H LA++ +G V++WG N SG+LG  D   R + ++        L V + ACG+ H+++LT  G  +S G + +GQ G G  V+ R  P  +  SDLIG  V +IA     ++ +   GA + +G
Sbjct:  177 CIHRPEPVEQLSGVPIVRVLAG--ARHCLALSASGAVFTWGQNNSGELGIDDL--RPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAV--SDLIGSHVTRIAAGACHTIAICK-GAPYPFG 319

HSP 8 Score: 66.2402 bits (160), Expect = 6.531e-10
Identity = 82/335 (24.48%), Postives = 142/335 (42.39%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDEL-----------QNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELE-----NLQIPYSVTAIDGKEVNLNIETSGAIF--VNASNRNSYIDEVINYKIH-----EFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRG-VKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            KV + GE  DD GG   E    +  ++           +  HL +F   P + C          + + F  LG L+G++I  +  +       ++K L     +  DL          L  L + +E ++E     N  I +++      E +     SG     V  +NR+ Y+   +++++      E  +  L  R+G S  +    L  F   EL+ ++ GN++   +  + I +YRG   S    I  FW+    +T++ R  FL+F+ G TR+P     + G E +   +   +P  + LP A+TCF LL LPN +    L  +L  +I
Sbjct:  697 KVNIAGEDADDAGGVRKEFFILVMRKILQSDYGMFSEDEESHLVWFSGLPSEFC----------DREQFHQLGRLVGLSIYNHSIVPFPFPLALYKYLLDTPPDLEDLCELSPSEGKGLKMLLSYEEDDVEDVFGLNFCISFNILG----ETHTTELLSGGTEKPVTNANRDEYVRLYVHHRLELGYNGEIAQQALLFRKGFSESLHSRTLRFFQPCELKEMIVGNENYDWNEFRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFLTGSTRIP-----VSGWEELHAAIQPSAP--ESLPVAHTCFNLLDLPNIADDVELLRRLRISI 1010

HSP 9 Score: 60.8474 bits (146), Expect = 3.588e-8
Identity = 51/227 (22.47%), Postives = 100/227 (44.05%), Query Frame = 2

Query: 1613 DVDANIYSS------HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLG-HGDVKDRHLPIRITA-SDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGE 2269
            D+D    +S      H + +T+ G+++S G+N  G+LG+G ++     +I         ++ Q++ G  H++ +T  G +++ G N  GQLG       +  P R+   +D++     Q+A   +  + L   G +F WG   D    H      + E         I ++         L  SG+V+TW +  +     DD++P+      +Q+D + ++    G+
Sbjct:   37 DMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRG-SRTEGSFSIYPVSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEINDIV-----QVASGSNHCIALDEGGRVFVWGEQADGRCIH------RPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGD 251

HSP 10 Score: 59.3066 bits (142), Expect = 8.479e-8
Identity = 43/145 (29.66%), Postives = 67/145 (46.21%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLG-------QGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  ++I + A    SH ++VT+ G+V++WG+N  G+LG       QG    R+   I D        + QVA G  H + L + G ++  G    G+  H     R  P+      L GV + ++       + LS  GA+FTWG
Sbjct:   92 SSAKIIQISAG--RSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQG--TPRRVQEIND--------IVQVASGSNHCIALDEGGRVFVWGEQADGRCIH-----RPEPVE----QLSGVPIVRVLAGARHCLALSASGAVFTWG 215

HSP 11 Score: 55.4546 bits (132), Expect = 1.336e-6
Identity = 37/137 (27.01%), Postives = 72/137 (52.55%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            N ++ V +   S+H +A+ E G+V+ WG        Q D +   RP  ++  S   + + +V  G  H L L+ SG +++ G+N+ G+LG  D++ +     +   D +GV+  + A   + ++ L++ G  F++GS
Sbjct:  145 NDIVQVASG--SNHCIALDEGGRVFVWGE-------QADGRCIHRPEPVEQLS--GVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVV--EAACGDNHTVLLTHCGRTFSFGS 268

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Query: 9590 AGDSSNGRLGI---GSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLN---YPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG-HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNG-TVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
             G +  G+LG+    S   +   +I  P  ++          +V  G +H + LTK+G+ +S G   DG+LG  SR + +   YP  + +    +++ ++ G SH+ ++   G ++ WG  ++G+LG       +  P  V+ + D  +VQVA GS     +AL     V+ W        G      C+  P+ +E +S   ++++  GA+   AL+ +G V+TWG+ +   LG    +       +  +    +V  A G  H + +T  G+ +S+G +  GQ G G  V     PT VS L+ + +  +A G+ H++A
Sbjct:    8 CGHTGEGQLGVRLSESTIQVPERIIGAPNDMDG-----TAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYP--VSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEIND--IVQVASGSN--HCIALDEGGRVFVW--------GEQADGRCIHRPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIA 309

HSP 2 Score: 94.7449 bits (234), Expect = 1.670e-18
Identity = 87/325 (26.77%), Postives = 149/325 (45.85%), Query Frame = 2

Query: 12614 GFGNNGRLGIGSTES-VQTPILVSGLEEKI--VVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTT-TNSRPRIIESLTGKGINRVACGSAHTLA 13573
            G    G+LG+  +ES +Q P  + G    +      +V  G +H + L  +G +++ G   D +LG   R +    +   +   S   A+II I+AG SH+ +++  G ++ WG   +G+LG  +    Q  P+ V+ +    ++ VA GS      CI  +E  R+       VW           +        P  +E L G  +++V  G++  L L+ASG V+TWG+ +   LG          + V Q++   +++ ACG  H +  T  G  +S+G +  GQ G G      + P  +  L G  + R+A G+ HT+A
Sbjct:    9 GHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYPVSWTSS---AKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEIND--IVQVASGSNH----CIALDEGGRV------FVWG---------EQADGRCIHRPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIA 309

HSP 3 Score: 93.2041 bits (230), Expect = 4.605e-18
Identity = 98/377 (25.99%), Postives = 164/377 (43.50%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLG-GVEGSKIKVPVLC----EHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGS-TESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG-------SGDAQTLCITKNEDSRI---DLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVR-KPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESL 13522
            E+   GH   GQLG  +  S I+VP         +       +  GEQ    ++ DG++++ G   +G+LG GS TE   +   VS      +++++  +G  H +++ ++G V+AWG  E  +LG++ +        TP  V+ +   +I+ +A+G +H  A+   G ++ WG+   GR  H        P+ VE L G  ++ V  G       S         +N    +   DL P TSV                        +  ++G GV++  CG   +++LT  G  +++G     + G G     R  P  V+ L    +  +A G+ H I   + G  Y +G N  GQLG+G   T S PR  + L
Sbjct:    4 ELLGCGHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYPVSWTSSAKIIQIS--AGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQG---TPRRVQEI--NDIVQVASGSNHCIALDEGGRVFVWGEQADGRCIHR-------PEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSV----------------------QHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGACHTIAICK-GAPYPFGLNSSGQLGNGKIMTQSTPRKTDEL 343

HSP 4 Score: 89.3521 bits (220), Expect = 6.488e-17
Identity = 70/269 (26.02%), Postives = 124/269 (46.10%), Query Frame = 2

Query: 9752 GETFSWGEGDDGKLGHN-SRLKLNYPRKI----KYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG---DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWT 10531
             E    G   +G+LG   S   +  P +I        G  V  V CG  H+  +   G +++ G    G+LG G   + +  ++P  V      K++Q++ G   + T+++T D  V++WG  + G+LG          P++++   +++++Q+  G+    AL E G+V+ WG+           + I  P  +E L    IV +  GA HCLA++  G V++WG N+ G+ G   +        V  +    +   ACG +H+V  T
Sbjct:    3 AELLGCGHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRGSRTEGSFSIYP--VSWTSSAKIIQISAGR--SHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQ--EINDIVQVASGSNHCIALDEGGRVFVWGE-------QADGRCIHRPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLT 258

HSP 5 Score: 86.6557 bits (213), Expect = 4.127e-16
Identity = 60/215 (27.91%), Postives = 102/215 (47.44%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSEL-DCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG-DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLAL 10060
            +++ WG N+  QLG E  SK         + E+ D V ++ GS     +   G+V+V G+ ++GR             I  P+ +E L    IV+V   +G RH +AL+ +G  F+WG+ + G+LG +        + +    G  VV+ ACG +H+  +   G  +++G    G+ G G     R +P  V  L    V ++A G+    T+A+
Sbjct:  114 RVFAWGSNEHGQLGME--SKFTWQGTPRRVQEINDIVQVASGSNHCIALDEGGRVFVWGEQADGR------------CIHRPEPVEQLSGVPIVRVL--AGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAGA--CHTIAI 310

HSP 6 Score: 71.2478 bits (173), Expect = 2.495e-11
Identity = 36/119 (30.25%), Postives = 58/119 (48.74%), Query Frame = 2

Query: 13223 VIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            +++V  GS   + L   G V+ WG+    R  H       +PE V QL+   I+ V  G+ HC+  +  G V++WG N+ G+LG       +  + +  + G G+   ACG  HT+  T
Sbjct:  147 IVQVASGSNHCIALDEGGRVFVWGEQADGRCIH-------RPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLT 258

HSP 7 Score: 69.3218 bits (168), Expect = 8.129e-11
Identity = 47/150 (31.33%), Postives = 78/150 (52.00%), Query Frame = 2

Query: 1562 CLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHG-DVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            C+     ++  S   ++ V A   + H LA++ +G V++WG N SG+LG  D   R + ++        L V + ACG+ H+++LT  G  +S G + +GQ G G  V+ R  P  +  SDLIG  V +IA     ++ +   GA + +G
Sbjct:  177 CIHRPEPVEQLSGVPIVRVLAG--ARHCLALSASGAVFTWGQNNSGELGIDDL--RPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAV--SDLIGSHVTRIAAGACHTIAICK-GAPYPFG 319

HSP 8 Score: 66.2402 bits (160), Expect = 6.531e-10
Identity = 82/335 (24.48%), Postives = 142/335 (42.39%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDEL-----------QNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELE-----NLQIPYSVTAIDGKEVNLNIETSGAIF--VNASNRNSYIDEVINYKIH-----EFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRG-VKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            KV + GE  DD GG   E    +  ++           +  HL +F   P + C          + + F  LG L+G++I  +  +       ++K L     +  DL          L  L + +E ++E     N  I +++      E +     SG     V  +NR+ Y+   +++++      E  +  L  R+G S  +    L  F   EL+ ++ GN++   +  + I +YRG   S    I  FW+    +T++ R  FL+F+ G TR+P     + G E +   +   +P  + LP A+TCF LL LPN +    L  +L  +I
Sbjct:  697 KVNIAGEDADDAGGVRKEFFILVMRKILQSDYGMFSEDEESHLVWFSGLPSEFC----------DREQFHQLGRLVGLSIYNHSIVPFPFPLALYKYLLDTPPDLEDLCELSPSEGKGLKMLLSYEEDDVEDVFGLNFCISFNILG----ETHTTELLSGGTEKPVTNANRDEYVRLYVHHRLELGYNGEIAQQALLFRKGFSESLHSRTLRFFQPCELKEMIVGNENYDWNEFRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFLTGSTRIP-----VSGWEELHAAIQPSAP--ESLPVAHTCFNLLDLPNIADDVELLRRLRISI 1010

HSP 9 Score: 60.8474 bits (146), Expect = 3.588e-8
Identity = 51/227 (22.47%), Postives = 100/227 (44.05%), Query Frame = 2

Query: 1613 DVDANIYSS------HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLG-HGDVKDRHLPIRITA-SDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGE 2269
            D+D    +S      H + +T+ G+++S G+N  G+LG+G ++     +I         ++ Q++ G  H++ +T  G +++ G N  GQLG       +  P R+   +D++     Q+A   +  + L   G +F WG   D    H      + E         I ++         L  SG+V+TW +  +     DD++P+      +Q+D + ++    G+
Sbjct:   37 DMDGTAVTSVTCGEQHTVFLTKDGKMWSVGSNMDGQLGRG-SRTEGSFSIYPVSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQGTPRRVQEINDIV-----QVASGSNHCIALDEGGRVFVWGEQADGRCIH------RPEPVEQLSGVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVVEAACGD 251

HSP 10 Score: 59.3066 bits (142), Expect = 8.479e-8
Identity = 43/145 (29.66%), Postives = 67/145 (46.21%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLG-------QGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  ++I + A    SH ++VT+ G+V++WG+N  G+LG       QG    R+   I D        + QVA G  H + L + G ++  G    G+  H     R  P+      L GV + ++       + LS  GA+FTWG
Sbjct:   92 SSAKIIQISAG--RSHTVSVTDDGRVFAWGSNEHGQLGMESKFTWQG--TPRRVQEIND--------IVQVASGSNHCIALDEGGRVFVWGEQADGRCIH-----RPEPVE----QLSGVPIVRVLAGARHCLALSASGAVFTWG 215

HSP 11 Score: 55.4546 bits (132), Expect = 1.336e-6
Identity = 37/137 (27.01%), Postives = 72/137 (52.55%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            N ++ V +   S+H +A+ E G+V+ WG        Q D +   RP  ++  S   + + +V  G  H L L+ SG +++ G+N+ G+LG  D++ +     +   D +GV+  + A   + ++ L++ G  F++GS
Sbjct:  145 NDIVQVASG--SNHCIALDEGGRVFVWGE-------QADGRCIHRPEPVEQLS--GVPIVRVLAGARHCLALSASGAVFTWGQNNSGELGIDDLRPQTSVQHVHQMDGLGVV--EAACGDNHTVLLTHCGRTFSFGS 268

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Celegans
Match: Y92H12A.2 (E3 ubiquitin-protein ligase [Source:UniProtKB/TrEMBL;Acc:Q9BKW4])

HSP 1 Score: 106.301 bits (264), Expect = 8.066e-23
Identity = 94/326 (28.83%), Postives = 172/326 (52.76%), Query Frame = 2

Query: 14129 LPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFF-ISSPDKDCFVLSPYADKTNTK---WFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVT-AIDGKEVNLNIETSGA-IFVNASNRNSYIDEVINYK-IHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYR-GVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLP-RYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            L N++W ++  GE+  D GG   E    +  ++ N +   F  S+ D     ++P+++  N +   +F F+G ++G+AI   + L        +K++ G+ +   D++  D +  +SL+ +K  D  +LE   + +S+  +I G+  N+ +  +GA + V   N+  YI+ VI+++ ++  +K    I +G+  V+P  LL LF + ELE L+CG   I +   K+ T+Y+ G      ++  FW+ +    NE+R+  L+FV G +R+P     +L G   + +   +   + D LP A+TCF  L LP Y++   L+ KLL AI
Sbjct:  165 LRNKLW-IEFFGETGLDYGGVTREWFFLLSHQIFNPYYGLFEYSATDNYTLQINPHSEACNPEHLSYFHFIGRIIGMAIYHGKLLDAFFIRPFYKMMLGKKITLFDMESVDNEYYNSLIYVKDNDPADLE---LTFSLDDSIFGETQNIELIPNGANVPVTEDNKEEYIEAVISWRFVNRIEKQMNQILKGLQEVVPSNLLRLFDANELELLMCGLQKIDVKDWKANTIYKGGYGPSSQVVHNFWKCILSFDNEMRARVLQFVSGTSRVPMNGFRELYGSNGLQKFTIERWGSADMLPRAHTCFNRLDLPPYTTFKELKSKLLTAI 486

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Celegans
Match: glo-4 (X-linked retinitis pigmentosa GTPase regulator homolog [Source:UniProtKB/Swiss-Prot;Acc:Q5DX34])

HSP 1 Score: 101.679 bits (252), Expect = 1.459e-20
Identity = 82/344 (23.84%), Postives = 141/344 (40.99%), Query Frame = 2

Query: 9530 SISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLN--YPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSN-------------------------------------------VIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQG 10426
            +I+ G++ +  ++ +G++   G +  G+ G+G    I          L  +D  +     +  G  H+  +  +G  +++G G  G+LGH  R   N   P ++     K V  +ACG +H+  +   G +   G G YG++G  D   ++       L   +V  +A  +    ++ +T D  V+ WG        R       + +KI    L N                                           ++ + CG   S  +T  G ++TWGKG  Y+LGHG      EP Q+ +    K V++++G  H +A TD G V++WG ND GQ G
Sbjct:  774 AIACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIA--------NLHQVDGDWPAIEKIACGQFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLICK-VTQIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDDDIKKVFAFTPLPLGPLRVRDIA--THYYHSICITEDNRVFEWGRNPQELKMRM-----FVMKKIRSAQLKNTEDPSSPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTDDGSVFAWGKNDFGQCG 1101

HSP 2 Score: 84.3445 bits (207), Expect = 2.523e-15
Identity = 88/340 (25.88%), Postives = 156/340 (45.88%), Query Frame = 2

Query: 12542 RPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKN----------EDSRIDLVPNTSVWSWXXXXXXXXXXXXXXI--------CKLPMKI-----------ETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLG 13474
            RPR I  G + + ++S  G++ A G    G+ G+G +  +     V G +   + K+A   G  H   +C++G ++ +G     +LG   R    +  L PT V  L+  ++  IA G +H+  ++ +G +   G G YG++G  +   + F      L    V  +A  +    ++CIT++          ++ ++ +     + S    +                     LP +I             L+G  ++ V CG   S ++T+ G +YTWGKG  ++LGHG+ N   +P +V + N  K ++V+ G+ H I  T+DG V++WG ND GQ G
Sbjct:  771 RPRAIACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLHQVDG-DWPAIEKIAC--GQFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQ--LVPTRVNGLI-CKVTQIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDDDIKKVFAFTPLPLGPLRVRDIA--THYYHSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPSSPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDG-NIVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTDDGSVFAWGKNDFGQCG 1101

HSP 3 Score: 73.559 bits (179), Expect = 4.898e-12
Identity = 84/319 (26.33%), Postives = 132/319 (41.38%), Query Frame = 2

Query: 9707 AVHSGGRHAIALTKNGETFSWGEGDDGK--LGHNSRLKLNYPRKIKYFKG--KRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG--DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGK----------------------------------GDYYRLGHGTDKHI-REPMQIEDLKK---TKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWT 10531
            A+  G  H + L+ +G+  +WG    G+  +GH+ R+       +    G    +  +ACG  HSA I   G L+T+G G +G+LGHG  + + +L P  V  L   KV Q+ACG   A T+ LT    V   G G +G++G       +       +    V  I      S  +TE+ +V+ WG+                                  G   R+       I RE + + ++K      IV +A G  H   +T  G +Y+WG     Q G+G     M P  V      K  +V+ G++H++A T
Sbjct:  774 AIACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIA-----NLHQVDGDWPAIEKIACGQFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI-CKVTQIACGR--AHTVVLTDTGRVLVCGSGSYGQMGVDDDIKKVFAFTPLPLGPLRVRDIATHYYHSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPSSPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIAST 1084

HSP 4 Score: 67.0106 bits (162), Expect = 4.225e-10
Identity = 54/202 (26.73%), Postives = 93/202 (46.04%), Query Frame = 2

Query: 9824 PRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGR--LGHGDTAMRLHPELVKSLRDYKVVQ-VACGSRDAQTLALTSDFTVWS--WXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLK--KTKIVHLAVGALHCLAVTDRGQVYSWGDN 10408
            PR ++Y  G R   +ACG+ H   +   G L  WG   +G+  +GH      LH    +   D+  ++ +ACG     +  + SD ++W+  WG       G   +S  L+P ++  + +  V QI CG   +  LT+ G+V   G G Y ++  G D  I++      L     ++  +A    H + +T+  +V+ WG N
Sbjct:  762 PRVLEY-PGGRPRAIACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLH----QVDGDWPAIEKIACG--QFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGL-ICKVTQIACGRAHTVVLTDTGRVLVCGSGSYGQM--GVDDDIKKVFAFTPLPLGPLRVRDIATHYYHSICITEDNRVFEWGRN 953

HSP 5 Score: 63.5438 bits (153), Expect = 5.006e-9
Identity = 54/208 (25.96%), Postives = 82/208 (39.42%), Query Frame = 2

Query: 1394 LPRELN-EKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR--PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            LPR L     R + I C      VLS  G L     +         F    + H F       V   W     I         H   +   G ++++G    G+LG G   +  +  PT ++       +V Q+ACG  H+++LT +G +  CG    GQ+G  D  D       T   L  + V+ IA   + S+C++ D  +F WG
Sbjct:  761 LPRVLEYPGGRPRAIACGAEHILVLSSSGQLSAWGGNR--------FGQCGVGHSFRIANLHQVDGDWPAIEKIACG----QFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI---CKVTQIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDD--DIKKVFAFTPLPLGPLRVRDIATHYYHSICITEDNRVFEWG 951

HSP 6 Score: 58.9214 bits (141), Expect = 1.182e-7
Identity = 55/246 (22.36%), Postives = 95/246 (38.62%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSS-------DDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNT--------------SGKLGQGDTKDRKRPTIIDTFSRCHLQVK----------------------QVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGST-FDNC 2026
            ++ +I C    T VL+D G +    + S       DD+   F F               + L L    RV D+  + Y  H + +TE  +V+ WG N               S +L   +      P+   +  R +L +                        VACG  HS ++T  G +Y+ G+    QLGHG+  +R  P ++   +  G     +++  + ++  ++DG++F WG   F  C
Sbjct:  875 KVTQIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDDDIKKVFAF---------------TPLPL-GPLRVRDIATHYY--HSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPSSPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPN--GAKWVNVSLGNNHTIASTDDGSVFAWGKNDFGQC 1100

HSP 7 Score: 55.8398 bits (133), Expect = 1.265e-6
Identity = 47/175 (26.86%), Postives = 76/175 (43.43%), Query Frame = 2

Query: 10184 IECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNG--TVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQ 10702
            I CGA+    L+ +GQ+  WG   + + G G    I    Q+ D     I  +A G  H   +   G ++++G    GQ G+G    +  + PT V+ L+  K+  +ACG +H+V  T +       S +  +          + V D    +F F P PLG   V DI  + + 
Sbjct:  775 IACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLHQV-DGDWPAIEKIACGQFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI-CKVTQIACGRAHTVVLTDTGRVLVCGSGSYGQ----------MGVDDDIKKVFAFTPLPLGPLRVRDIATHYYH 937

HSP 8 Score: 54.6842 bits (130), Expect = 2.859e-6
Identity = 34/126 (26.98%), Postives = 62/126 (49.21%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            + H+L ++ +GQ+ +WG N  G+ G G +    R   +         ++++ACG+ HS  +   G +++ G    GQLGHG   + +  +    + LI   V QIA     ++ L++ G +   GS
Sbjct:  779 AEHILVLSSSGQLSAWGGNRFGQCGVGHSF---RIANLHQVDGDWPAIEKIACGQFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI-CKVTQIACGRAHTVVLTDTGRVLVCGS 900

HSP 9 Score: 53.1434 bits (126), Expect = 7.709e-6
Identity = 35/118 (29.66%), Postives = 60/118 (50.85%), Query Frame = 2

Query: 13232 VDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSR--PRIIESLTGKGINRVACGSAHTLAWT 13579
            + CG++  LVL++SG++  WG   + + G G    +    +V   +   I  +ACG  H      DG ++++G    GQLG G    +++  P  +  L  K + ++ACG AHT+  T
Sbjct:  775 IACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLHQVDG-DWPAIEKIACGQFHSAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLICK-VTQIACGRAHTVVLT 890

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Celegans
Match: Y92H12A.2 (E3 ubiquitin-protein ligase [Source:UniProtKB/TrEMBL;Acc:Q9BKW4])

HSP 1 Score: 89.3521 bits (220), Expect = 5.560e-17
Identity = 89/325 (27.38%), Postives = 159/325 (48.92%), Query Frame = 2

Query: 14129 LPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFF-ISSPDKDCFVLSPYADKTNTK---WFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVT-AIDGKEVNLNIETSGA-IFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYR-GVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLP-RYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            L N++W ++  GE+  D GG   E    +  ++ N +   F  S+ D     ++P+++  N +   +F F+G ++G+AI   + L        +K++ G+ +   D++  D +  +SL+ +K  D  +LE   + +S+  +I G+  N+ +  +GA + V   N+  YI+                       V+P  LL LF + ELE L+CG   I +   K+ T+Y+ G      ++  FW+ +    NE+R+  L+FV G +R+P     +L G   + +   +   + D LP A+TCF  L LP Y++   L+ KLL AI
Sbjct:  416 LRNKLW-IEFFGETGLDYGGVTREWFFLLSHQIFNPYYGLFEYSATDNYTLQINPHSEACNPEHLSYFHFIGRIIGMAIYHGKLLDAFFIRPFYKMMLGKKITLFDMESVDNEYYNSLIYVKDNDPADLE---LTFSLDDSIFGETQNIELIPNGANVPVTEDNKEEYIE----------------------AVVPSNLLRLFDANELELLMCGLQKIDVKDWKANTIYKGGYGPSSQVVHNFWKCILSFDNEMRARVLQFVSGTSRVPMNGFRELYGSNGLQKFTIERWGSADMLPRAHTCFNRLDLPPYTTFKELKSKLLTAI 714

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Fly
Match: HERC2 (gene:FBgn0031107 transcript:FBtr0301344)

HSP 1 Score: 923.309 bits (2385), Expect = 0.000e+0
Identity = 563/1377 (40.89%), Postives = 782/1377 (56.79%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNE--IELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVS---------------TAD--EWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLK-----------EPTVKDP------------------------LTREINAI---------TAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGK---LIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSP-YADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETE--LENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +++ES HPY +N  ++G V IP A  L +EFD QCSTE+  D LVIMD    ++A RSG+ +  W  ++ + G+EL W F SD S+  WGWRF V         + I    T     ++   L  P++ L+  LL+      Q          + + SQ+      L    RIW++R++ A++                              L  Q   P +P+                            +   L  L   +L+Q+++EEP+V+    L +S + K+L  L+C ++LD+  P +               T D  +WAWF+ YC+  R  +SLI  + LP  F  E + +F +            P  + P                        +T E   +         T+   + D   F   HD Q++ WL  RPD W   W         ++ WGHNHRGQLGG+EGS+IK P  CE LS LRP Q+ GGEQSLF V+ DG+++ATG+G+ GRLG+G ++S   P L+  L+   V KVAVNSGGKHCLAL   G VYAWG+ ED KLG   R+        P LV+ L    + DIA G +HSAAI+ SG + TWGKGRYGRLGHG+ +DQ  PK+VEAL GY  I +ACGSGDAQTLCIT +++          VWSWGDGDYGKLGRGG D CKLP KIE+L G GV+KV+CGSQFS+ LT SG VYTWGKGD+ RLGHGS +HVR+P+KVA L  KKII +A GSLHC+ C++ GEVY+WGDNDEGQLGDGT T   RPR++ +L GK I +V CGSAHTLA +T        ++  ++   L   P   +L+ + +  +L  R +LLHH++EL C  L  + ++    +  ++ +L+ + KE+ FR ++QTTM   K+HGP I++NR+                             + + + C G   I   K+VFGQ+  K   L +EA                  LP+RVWKVK +GESVDDCGGGYSESI E+CDELQNG +P  I++P        ++DCF+L P  +       F FLG L+GIA+RT  PLS+ +++ +W+ L+G+ L   DL   D+D ++ L+ ++ +D+       L++P+S ++  G EV L+   +    ++  NR  Y+   + +++HEFD+    +R G+S VIP+PLL+LFS+ EL+ +VCG+  IP+  LKS+  Y+G      ++ WFWE+MEE TN+ RSLFLRFVWGRTRLPR ++D RG++FV+QVL K +P D +LPE+YTCFFLLK+P YS KA+L EKL YAIHFCKSID D+YAR+A+ 
Sbjct: 3658 VMQESSHPYVDNVNVTGVVRIPGAEMLRLEFDSQCSTEKRNDPLVIMDGTGRVLAMRSGREFAHWAPEIRVLGDELRWKFSSDSSVNGWGWRFWV---------HAIMPAATLGESGSDRAVLSQPSMALVMSLLDSRLAPRQPSVLLRLASALAACSQLGA----LTTAQRIWSLRKLHAVL------------------------------LLEQAPRPQDPS----------------------------LSTLLQPLIPELLRQYEYEEPQVRGGIHLMHSDYFKTLAALACDMQLDAALPATSSSSSSSAAPGAISSTGDVHKWAWFKRYCIAVRVAQSLIRRTELPRAFCLEVRKKFAEMLPSSSSNSNANPGCQSPGASMLNSTTSLSSSTVSNVSPPPGITGEQPDLHCHAHQLESTSTLLHEDHTLFQAPHDAQLLQWLNRRPDDWALSW----GGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRM----SYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDN----------VWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALST--------SQLSERLRPLPNPPLEYDLVRDLAPEALHARLILLHHFSELVCPCLAMLPISGDLSLGALKDVLVYNIKEAAFRKVIQTTMVRDKQHGPVIELNRIQV---------------------------KRSRNRCNGLAGIDGMKSVFGQMVQKLPLLTQEA----------------LALPHRVWKVKFVGESVDDCGGGYSESIAEMCDELQNGSVPLLINTPNGRGEAGANRDCFLLDPTLSSVLQMNMFRFLGVLMGIAVRTGSPLSINLAEPVWRQLTGEVLRPTDLTEVDRDYVAGLLCIRNMDDDPKLFTALELPFSTSSARGHEVPLSTRYT---HISPRNRAEYVRLALGFRLHEFDEQVKAVRDGMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYKGFDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADFRGRDFVLQVLEK-NPPDHFLPESYTCFFLLKMPRYSCKAVLLEKLKYAIHFCKSIDTDEYARVAMG 4890

HSP 2 Score: 433.721 bits (1114), Expect = 1.051e-120
Identity = 225/396 (56.82%), Postives = 286/396 (72.22%), Query Frame = 2

Query: 9341 PTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAW 10528
            P + +   + +T   +  +  +  +   + VWGLNDK+QLG    SKVK+P  ++ +S L  + I+GGSKSLF V++ GKVY  G+ +NGRLG+G    +T  V + P +L  L +Y + KVAVHSGG+HA+ALT +G+ FSWGEG+DGKLGH +R  L+ PR ++  + K++ DVACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P+LV +L   +VVQVACGSRDAQTLALT D  V+SWGDGDFGKLGRGGS G   P +IE +S   V+QIECGAQ S ALT  G+VWTWGKGDYYRLGHG D+H+R+P  I  L+  +++H+AVGALHCLAVTD GQVY+WGDNDHGQQG+G    N +P LV  L    +  VACGSSHS+AW
Sbjct: 2960 PGSTAGAGAVSTSHEEAAAAPEQDLPCTVMVWGLNDKEQLGGLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLG----VTHNVPL-PHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIAW 3350

HSP 3 Score: 362.459 bits (929), Expect = 3.446e-99
Identity = 193/379 (50.92%), Postives = 262/379 (69.13%), Query Frame = 2

Query: 9419 SKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFL 10555
            S IY WG N + QLG    S++K P   EALS L  V ++GG +SLF VT  GK++  G  S GRLG+G         ++G     +L   F+ KVAV+SGG+H +ALT  GE ++WGEG+DGKLGH +R+  + P+ +++  G  V D+ACGS+HSAAI   GH+ TWG G YGRLGHGD+  +L P+LV++L  Y+ + +ACGS DAQTL +T D  VWSWGDGD+GKLGRGGS GC +P KIE ++   V+++ECG+Q S ALT++G V+TWGKGD++RLGHG+  H+R P ++  L+  KI+ +A G+LHC+A +D G+VY+WGDND GQ G+GTVT   RP LV+AL    I  V CGS+H++A + S L   L
Sbjct: 4049 STIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLG-----SLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQLSERL 4422

HSP 4 Score: 352.443 bits (903), Expect = 3.993e-96
Identity = 203/391 (51.92%), Postives = 264/391 (67.52%), Query Frame = 2

Query: 12446 VWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESP 13618
            V  WG N + QLGG++GSK+KVP   + +S LRP  I GG +SLFIVS DG+VYA G G NGRLG+G T +V  P  +  L + +V KVAV+SGGKH LAL  +G V++WG+ ED KLG   R      +  P LV++L   +I D+A G SHSAAIS  GELYTWG G YGRLGHG+   Q  PK+V AL G  V+ VACGS DAQTL +T++           +V+SWGDGD+GKLGRGG +    P +IE L G GV++++CG+QFSL LT +GEV+TWGKGDY+RLGHG D HVRKP+ +  L  +++I VA G+LHC+  T+ G+VY+WGDND GQ G G T  N +P ++  L    +NRVACGS+H++AW   + +   E   P
Sbjct: 2988 VMVWGLNDKEQLGGLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRT----TLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTED----------GAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIAWGLPNASSDEEKRGP 3364

HSP 5 Score: 180.644 bits (457), Expect = 3.362e-44
Identity = 120/298 (40.27%), Postives = 171/298 (57.38%), Query Frame = 2

Query: 9662 PKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-TDKHIRE---PMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYN--MRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            P  +E +     + +A H  GRH +A+  N   +SWG G+D +LGH        P KI   +   V  V CG S+SAAI  GG+L TWG G Y RLGHG++  R  P LV +L D+ VV VA GS DA +LALTS+  V++WGDGD+GKLG G  +G L P  +E  SL  V ++  G+Q S AL+  GQ++TWGK     LGH   ++ ++    P  +  L+  +IV +AV   HCLA++  G+V+ WG ND  Q    +V+    +R  ++ +L     + +AC S+ S+ WT S
Sbjct:  605 PLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVE--SLPRVQRVFAGSQFSVALSSEGQLYTWGKATC--LGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWTQS 898

HSP 6 Score: 149.058 bits (375), Expect = 1.037e-34
Identity = 125/354 (35.31%), Postives = 186/354 (52.54%), Query Frame = 2

Query: 12548 RQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-DIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHG----SDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNS--RPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +Q+   E  + I+S +G++Y        RL     E    P+ +  +   + + +A +  G+H LA+ +N   Y+WG  ED++LG  D   +       PT + +L +  +  +  G S+SAAI+  G L TWG+G Y RLGHGN DD+  P +V AL  + V+ VA GSGDA +L +T              V++WGDGDYGKLG G  +    P+ +E+L    V +V  GSQFS+ L++ G++YTWGK     LGH     S      P  V+ L  K+I+DVA    HC+  +  GEV+ WG ND  Q+   + ++    R  I+ SL     + +AC SA +L WT  S
Sbjct:  575 KQVACCETQMLILSQEGKLY------TWRLAKPEAE----PLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHAR-----AVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTS----------EGLVFAWGDGDYGKLGNGNCNGSLQPILVESL--PRVQRVFAGSQFSVALSSEGQLYTWGKATC--LGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWTQSS 899

HSP 7 Score: 106.686 bits (265), Expect = 6.753e-22
Identity = 94/273 (34.43%), Postives = 135/273 (49.45%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLV 13261
            +V+SWG    G+LG    + +  P L E L A + R +  G      +S  G +Y  G G  GRLG G   +   P LV+ L  + VV+VA  S     LAL  +G V++WGD +  KLG       G D  TP  ++ L    ++ I  G   S A++R+GE++TWGKG Y RLGHG       P+ +  LRG  VI VA G+      C+   +  +        V++WGD D+G+ G G   + K P  +  L+   V +V CGS  S+ 
Sbjct: 3093 KVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRG--GSEGSD--TPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGA----LHCLAVTDAGQ--------VYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIA 3349

HSP 8 Score: 96.2857 bits (238), Expect = 9.254e-19
Identity = 71/229 (31.00%), Postives = 111/229 (48.47%), Query Frame = 2

Query: 9854 RVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            ++  VAC  +    +   G LYTW      RL   +      P  ++ +     + +A        LA+ S+   +SWG G+  +LG G +    +P KI  +    V  + CG   S A+T  G + TWG+G Y RLGHG       P  +  L    +V +A+G+   H LA+T  G V++WGD D+G+ GNG    +++P LV +L   ++  V  GS  SVA ++
Sbjct:  573 QIKQVACCETQMLILSQEGKLYTW------RLAKPEA----EPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESL--PRVQRVFAGSQFSVALSS 789

HSP 9 Score: 95.5153 bits (236), Expect = 1.823e-18
Identity = 65/195 (33.33%), Postives = 100/195 (51.28%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWGS-TFDNCRRHLSNWSPKIETCVNEYRNE----IDQIQVH-DSTYSV-LLKSGSVYTWLK 2164
            V  V  N    H LA+T  G+VY+WG    GKLG G+     RP +++  +   + V  +ACG  HS  +T SG + + G+   G+LGHGD +D+  P  + A  L+G     IA      Q++C+++D  +++WG   +    R  S      + C   Y+ E    +  ++V   S +SV L KSG+VYTW K
Sbjct: 4136 VKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLN--GMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEA--LLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGS------DGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGK 4320

HSP 10 Score: 88.5817 bits (218), Expect = 1.945e-16
Identity = 74/256 (28.91%), Postives = 117/256 (45.70%), Query Frame = 2

Query: 1406 LNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSR-CHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITA-SDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKS-GSVYTWLK 2164
            L+ +F+IK++ C      +LS  G LY    +  +                + L  + V    + +  I +  +    H LA+      YSWGT    +LG GDT  R  PT I    + C   V+ V CG  +S  +T  G++ + GR    +LGHG+  DR LP  + A SD + V V   + D H S+ L+++G +F WG   D  +    N +  ++  + E    + ++    S +SV L S G +YTW K
Sbjct:  568 LSCRFQIKQVACCETQMLILSQEGKLYTWRLAKPEA---------------EPLPMEEV----AHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHC---VQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAH-SLALTSEGLVFAWGDG-DYGKLGNGNCNGSLQPILVESLPRVQRV-FAGSQFSVALSSEGQLYTWGK 798

HSP 11 Score: 79.7221 bits (195), Expect = 1.070e-13
Identity = 45/135 (33.33%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            R ID+      +  L +T+   V+SWG    GKLG+G +   K P  I++ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG V     P ++ A  L G  +  IA      +  S+ G ++TWG
Sbjct: 4241 RAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLA--GLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAA--LQGKKIISIATGSLHCVACSDSGEVYTWG 4371

HSP 12 Score: 78.1814 bits (191), Expect = 2.849e-13
Identity = 44/135 (32.59%), Postives = 72/135 (53.33%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RV+ V      +  LA+TE G V+SWG    GKLG+G ++    P  I+  S   + V Q+ CG + SL LT++G++++ G+    +LGHG   D+H+        L G  V  +AV     + +++ G ++ WG
Sbjct: 3178 RVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLS--GIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGG--DQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWG 3308

HSP 13 Score: 77.7962 bits (190), Expect = 4.117e-13
Identity = 43/127 (33.86%), Postives = 67/127 (52.76%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            SSH  A++  G++Y+WG    G+LG GD   + +P ++   +    +V QVACG  +  +L LT+ G ++S G    G+LG G  +    P  I    L G+ V QI      S+ L+  G ++TWG
Sbjct: 3134 SSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALA--GRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEI--ERLSGIGVVQIECGAQFSLALTRAGEVWTWG 3256

HSP 14 Score: 70.4774 bits (171), Expect = 5.551e-11
Identity = 54/202 (26.73%), Postives = 94/202 (46.53%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNC------RRHLSNWS-PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTE--CNKSDDIQPELDT 2215
            S+  A+T  G + +WG  T  +LG G++ DR  PT++   S   +    +  G+ HSL LT  G +++ G    G+LG+G+      PI + +       V+++      S+ LS++G ++TWG     C       R +   S P++ + +   R  I  + V  +    L  SG V+ W +  ++  C  S   +P L T
Sbjct:  678 SYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLP----RVQRVFAGSQFSVALSSEGQLYTWGKA--TCLGHQLVERSVQGCSVPRLVSSLQHKR--IVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRT 871

HSP 15 Score: 67.0106 bits (162), Expect = 6.446e-10
Identity = 64/254 (25.20%), Postives = 108/254 (42.52%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVD--GHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYR-NEIDQIQVHDSTYSVLLKSGSVYTW----LKYCTECNKSDDIQPELDTVLKYQ-----------------VDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIK 2359
            V  WG N   +LG       K PT   T SR  L+   +A G +   I++Q G +Y+CG    G+LG G   +  LP ++    L   +VK++AV   G  ++ L+ DG +F+WG   D    H +  +      V   R  +I  +    S  + +   G +YTW           + +  ++P+L T L  +                  ++ ++ S GDG+F  L + G   +    +I   + SG G ++
Sbjct: 2988 VMVWGLNDKEQLGGLKGSKVKVPTFSQTISR--LRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPV--LRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEI--ERLSGIGVVQ 3235

HSP 16 Score: 66.2402 bits (160), Expect = 1.238e-9
Identity = 48/178 (26.97%), Postives = 82/178 (46.07%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            S  +  V++ G+VY+ G  T+G+LG G T +   P  +    +  ++   V  G +H+L LT  G ++S G    G+LGHG+      P  + A  L    ++ +A     S  +S+ G ++TWG        H  N +   PK+ T +   R         D+    L + G+V++W
Sbjct: 3028 SKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEA--LRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSW 3203

HSP 17 Score: 65.855 bits (159), Expect = 1.578e-9
Identity = 69/304 (22.70%), Postives = 131/304 (43.09%), Query Frame = 2

Query: 9185 ISNDILLKTIFSISDKNWSAEDIDTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVEN-QDNSKFKSRIM--SKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSL--FCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHN----SRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMR--LHPELVKSLRDYKVVQVACGSRDAQTLALT 10063
            +++D+ +        +++ A D     N+  Y+W     ++L    +++     T    L ++ V++      + + I     +  WG     +LG   +    LP L  ALS+   V ++ GS       +T  G V+  GD   G+LG G+       +++  + L  + + F       +G + ++AL+  G+ ++WG+     LGH     S    + PR +   + KR+VDVA   +H  A+   G ++ WG  D  ++     +    L   ++ SL  +    +AC S  AQ+L  T
Sbjct:  611 VAHDVFISIAGHCEGRHFLAID----SNHNAYSWGTGEDHRL-GHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILV--ESLPRVQRVF-------AGSQFSVALSSEGQLYTWGKAT--CLGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTS--AQSLVWT 896

HSP 18 Score: 64.3142 bits (155), Expect = 4.272e-9
Identity = 46/154 (29.87%), Postives = 68/154 (44.16%), Query Frame = 2

Query: 5762 LPSQLKKGTLVLRGRDWKYGDQDG--PNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISI 6217
            L   +K GT ++RG DWK+GDQDG  P    I+     +G VRV+W     T SYR GK+  YDL+L  S  +V + T  E                           E ++ S+               P++ + PS LL H A +L+Q +++
Sbjct: 1921 LAKLMKIGTRIVRGADWKWGDQDGNPPGEGRIISEVGEDGWVRVEWYTG-ATNSYRMGKEGQYDLQLADSALNVASPTEPE--------------------------REDVSGSEAS-------------PTSDSHPSKLLRHCAAKLLQILAV 2034

HSP 19 Score: 63.1586 bits (152), Expect = 9.073e-9
Identity = 43/140 (30.71%), Postives = 73/140 (52.14%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGR-NHMG-QLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S + V+DV      +H LA+T  G V++WG    GKLG G+     +P ++++  R    V++V  G + S+ L+  G +Y+ G+   +G QL    V+   +P R+ +S L    +  +AV     + LS+ G +F WG
Sbjct:  718 SDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLPR----VQRVFAGSQFSVALSSEGQLYTWGKATCLGHQLVERSVQGCSVP-RLVSS-LQHKRIVDVAVSVAHCLALSSSGEVFGWG 851

HSP 20 Score: 59.6918 bits (143), Expect = 1.245e-7
Identity = 37/117 (31.62%), Postives = 57/117 (48.72%), Query Frame = 2

Query:  485 LGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTDTLPFWSGVTEQTYQFLKNTVLC-PSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLK 832
            L  V   + +   F F++R WR G   D + C E++  A+  +QE+P A  F  +  +     W  V E++ +FL+   L  P  N    P   R  AL LLLE+G+  G L+  L+
Sbjct:  303 LARVATHAALNFSFAFLRRAWRSGE--DTEMCSELLSEALASLQELPEATLFEAAVVSS---LWLEVMERSIKFLRLVALGDPMGNRCTAPLNDRHTALCLLLELGVQKGTLAATLE 414

HSP 21 Score: 55.8398 bits (133), Expect = 1.639e-6
Identity = 30/69 (43.48%), Postives = 41/69 (59.42%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSL 1810
            RVI V   + + H LAVT+AGQVY+WG N  G+ G G+T   K+P ++         V +VACG  HS+
Sbjct: 3284 RVIHV--AVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVF--VNRVACGSSHSI 3348

HSP 22 Score: 55.0694 bits (131), Expect = 2.945e-6
Identity = 40/122 (32.79%), Postives = 64/122 (52.46%), Query Frame = 2

Query: 12446 VWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVY----ATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKL 12799
            V++WG    G+LG    +    P+L E L   R +++  G Q    +S +G++Y    AT  G+  +L   S +    P LVS L+ K +V VAV+    HCLAL ++G V+ WG  +  ++
Sbjct:  743 VFAWGDGDYGKLGNGNCNGSLQPILVESLP--RVQRVFAGSQFSVALSSEGQLYTWGKATCLGH--QLVERSVQGCSVPRLVSSLQHKRIVDVAVSVA--HCLALSSSGEVFGWGRNDSQQI 858

HSP 23 Score: 54.6842 bits (130), Expect = 3.600e-6
Identity = 34/116 (29.31%), Postives = 57/116 (49.14%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLS 1981
            S   +A+T++G VY+WG     +LG G     +RP  +        ++  +A G  H +  + SG++Y+ G N  GQLG G V     P R+ A+ L G  + ++      ++ LS
Sbjct: 4303 SQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQ--GKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRP-RLVAA-LQGKHIVKVTCGSAHTLALS 4414

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Fly
Match: Herc4 (gene:FBgn0035207 transcript:FBtr0072670)

HSP 1 Score: 152.525 bits (384), Expect = 4.657e-36
Identity = 101/324 (31.17%), Postives = 170/324 (52.47%), Query Frame = 2

Query: 9578 KVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG-DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXX---XXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            ++Y  G +S+G+LG+G   D   E I+ P ++       + +VA   G RH + LT  G+ ++ G  D  +LGH+  L    P  I   +   ++ + CGS HS A+   G + +WG  D G+LGH  D  +   P++V+ L    VVQ+ACG+    +LALTS   ++SWG   +G+LG       + C  P ++  +    +  I CG   SF ++++G V+ WG+ +  +LG   + +   P Q++ L+   +  +A G    + +T+ G V++ G   +GQ G+G  +  M P +V  LM + I  VACG+ H++A   S
Sbjct:    6 ELYCWGSTSHGQLGLGGIED---EQILTPSQIPWTPDTAVQQVAC--GHRHTLFLTATGKVYACGSNDYSQLGHD--LPTKRPLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNN--HSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPS 320

HSP 2 Score: 146.747 bits (369), Expect = 2.750e-34
Identity = 116/367 (31.61%), Postives = 184/367 (50.14%), Query Frame = 2

Query: 12431 ASGLEVWSWGHNHRGQ--LGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQP---FPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTED-GEVYSWGDNDEGQLGDGTTTTNSRPRII 13513
            ASG E++ WG    GQ  LGG+E  +I  P           +Q+  G +    ++  G+VYA G  +  +L  G     + P+L+  L++ +++++    G +H LAL + G V +WGD +  +LG        E V  P +V+ LV   ++ IA G +HS A++  GELY+WG   YG+LG  + +D     +P  +  L G  +  +ACG     +  I+K          + +V+ WG  + G+LG         P +++TL   GV  V CG +FS+ LT  G V+T G G Y +LGHG  ++   P  V +L    I  VACG+ H +      G VY++G    GQLG  +T +   P+++
Sbjct:    2 ASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQL--GHDLPTKRPLLIPELQDYVIIQICC--GSRHSLALSDWGQVLSWGDNDCGQLG---HATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISK----------SGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVV 349

HSP 3 Score: 144.821 bits (364), Expect = 1.055e-33
Identity = 120/426 (28.17%), Postives = 195/426 (45.77%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGC------EATSKVKLP-ILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKL-NYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG---HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLA-VTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLV---------SALMDNK-------IAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSV 10615
            ++Y WG     QLG       +  +  ++P   + A+ ++ C    G   +LF +T TGKVY  G +   +LG    T         P  +  L  Y I+++    G RH++AL+  G+  SWG+ D G+LGH +  ++   P+ ++    K VV +ACG++HS A+   G LY+WG   YG+LG     D     +P  + +L    +  +ACG     +  ++    V+ WG  + G+LG    +    P +++ +    V  + CG + S  LT  G V+T G G Y +LGHG   +   P  + +L  + I  +A G  H LA V  RG+VY++G    GQ G  +    M P +V         SAL+ +        I  +  G   S+  T   +D   P    N  P  + ++ +  V
Sbjct:    6 ELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVAC----GHRHTLF-LTATGKVYACGSNDYSQLGHDLPTK-------RPLLIPELQDYVIIQICC--GSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVVIGPWVSPSGSALLQSNDSQVSLVIRQIFSGGDQSIVTTTLFVDKVPPEDFRNYNPKSQILTLTAEV 415

HSP 4 Score: 120.168 bits (300), Expect = 3.424e-26
Identity = 103/336 (30.65%), Postives = 160/336 (47.62%), Query Frame = 2

Query: 12602 VYATGFGNNGRLGIGSTESVQ--TPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXX---XXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            +Y  G  ++G+LG+G  E  Q  TP  +    +  V +VA   G +H L L   G VYA G  + ++LG D+  +       P L+  L    II I  G  HS A+S  G++ +WG    G+LGH    +    PK+V  L    V+ +ACG+            +  + L     ++SWG   YG+LG         C  P+++ TL G  +  + CG   S +++ SG V+ WG+ +  +LG   + +   P ++  L    +  VACG    +  T +G V++ G    GQLG G ++    PR++  L G  I +VACG+ HTLA     G
Sbjct:    7 LYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVAC--GHRHTLFLTATGKVYACGSNDYSQLGHDLPTK------RPLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGN------------NHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRG 322

HSP 5 Score: 89.3521 bits (220), Expect = 8.933e-17
Identity = 60/215 (27.91%), Postives = 103/215 (47.91%), Query Frame = 2

Query: 1367 EIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCL-SNDGAIFTWG 2008
            EIV++   K+ R+L  K  + +I C    +  L+ CG LY   ++         +    +N   D    +  L+L +   +         +H   ++++G V+ WG N  G+LG  D  +R  PT + T     L V+ VACG+E S+ LT  G +++CG    GQLGHG   +  LP  +   +L+G  + Q+A     ++ L  + G ++ +G
Sbjct:  129 EIVQL--PKVVRQLVTK-TVVQIACGNNHSLALTSCGELYSWGSN--------IYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRT--LGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVM--ELMGSTITQVACGNRHTLALVPSRGRVYAFG 328

HSP 6 Score: 88.1965 bits (217), Expect = 1.785e-16
Identity = 53/135 (39.26%), Postives = 75/135 (55.56%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKD-RKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLG---HGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNC 2026
            S H LA+++ GQV SWG N  G+LG    K+  + P ++         V Q+ACG  HSL LT  G++YS G N  GQLG     D+   + P+R+T   L+G+ +  IA  G+ S  +S  GA+F WG   +NC
Sbjct:   99 SRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQL--VTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTT--LLGIPLAAIACGGNHSFLISKSGAVFGWGR--NNC 227

HSP 7 Score: 81.2629 bits (199), Expect = 2.643e-14
Identity = 65/242 (26.86%), Postives = 113/242 (46.69%), Query Frame = 2

Query: 1295 HKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR---PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            H L+            ND  +   ++   RP  +P EL + + I +I C    +  LSD G   +V +  D+  D     H       + ++   V++      V+ +     ++H LA+T  G++YSWG+N  G+LG     D      P  + T     + +  +ACG  HS ++++SG ++  GRN+ GQLG  D  +R  P ++     +GV  + +A     S+ L+N+G +FT G+
Sbjct:   51 HTLFLTATGKVYACGSNDYSQLGHDLPTKRPLLIP-ELQD-YVIIQICCGSRHSLALSDWG---QVLSWGDN--DCGQLGHATDK---EIVQLPKVVRQLVTKTVVQIACG--NNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTL--LGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGV--RFVACGDEFSVFLTNEGGVFTCGA 276

HSP 8 Score: 73.9442 bits (180), Expect = 4.818e-12
Identity = 40/114 (35.09%), Postives = 59/114 (51.75%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++Y WG+ + G+LG G  +D +  T           V+QVACG  H+L LT +G +Y+CG N   QLGH     R L I     +L   ++ QI      S+ LS+ G + +WG
Sbjct:    6 ELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPLLI----PELQDYVIIQICCGSRHSLALSDWGQVLSWG 115

HSP 9 Score: 70.4774 bits (171), Expect = 4.355e-11
Identity = 68/232 (29.31%), Postives = 102/232 (43.97%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKD-RHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-------EIDQIQVHDSTYSVLLKSGSVYTWLK-YCTECNKSDDIQPELDTVLK-YQVDNVSMISKGDGEFYFLDKSGIIRT 2305
            H L +T  G+VY+ G+N   +LG       KRP +I         + Q+ CG  HSL L+  G + S G N  GQLGH   K+   LP  +    L+   V QIA   + S+ L++ G +++WGS   N    L   SP   T  N            +  I    +   ++ KSG+V+ W +  C +   +D+      T LK  +   V  ++ GD    FL   G + T
Sbjct:   51 HTLFLTATGKVYACGSNDYSQLGH--DLPTKRPLLIPELQ--DYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVV--RQLVTKTVVQIACGNNHSLALTSCGELYSWGS---NIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFT 273

HSP 10 Score: 70.0922 bits (170), Expect = 5.752e-11
Identity = 84/320 (26.25%), Postives = 143/320 (44.69%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLF---DKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLF----IRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYR-GVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIH 15082
            K+K  GE  +D GG   E    +  +L +     F           +    +T   +F+ +G L G+AI     ++L     ++K L G+ ++ +DL+     + + + SL+  +  D  E+ +L    S       E          I V   NR  ++D  +++    F+K+         +G   V    ++++F   EL  +V GN+      L+    YR G  S D  I WFWE++ +M+   +  FL F+ G  R+P  +  ++  +  IQ     +P + +LP A+TCF LL LP Y +K  L+ KLL AI 
Sbjct:  741 KIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKYGMFKEYEQSRLLWFADLTFETENMYFL-IGVLCGLAIYNFTIINLPFPLALFKKLLGKPVDLSDLRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKCLKPNGNEIAVTLENRQEFVDLYVDFV---FNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVGNEDYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIP--IQGMKALKLTIQP----TPDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAIQ 1050

HSP 11 Score: 63.929 bits (154), Expect = 4.276e-9
Identity = 39/105 (37.14%), Postives = 53/105 (50.48%), Query Frame = 2

Query: 13268 ASG-EVYTWGKGDYFRLGHGS--DNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            ASG E+Y WG   + +LG G   D  +  P ++       +  VACG  H +  T  G+VY+ G ND  QLG    T   RP +I  L    I ++ CGS H+LA
Sbjct:    2 ASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPT--KRPLLIPELQDYVIIQICCGSRHSLA 104

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Fly
Match: Herc4 (gene:FBgn0035207 transcript:FBtr0072671)

HSP 1 Score: 152.525 bits (384), Expect = 4.657e-36
Identity = 101/324 (31.17%), Postives = 170/324 (52.47%), Query Frame = 2

Query: 9578 KVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG-DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXX---XXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            ++Y  G +S+G+LG+G   D   E I+ P ++       + +VA   G RH + LT  G+ ++ G  D  +LGH+  L    P  I   +   ++ + CGS HS A+   G + +WG  D G+LGH  D  +   P++V+ L    VVQ+ACG+    +LALTS   ++SWG   +G+LG       + C  P ++  +    +  I CG   SF ++++G V+ WG+ +  +LG   + +   P Q++ L+   +  +A G    + +T+ G V++ G   +GQ G+G  +  M P +V  LM + I  VACG+ H++A   S
Sbjct:    6 ELYCWGSTSHGQLGLGGIED---EQILTPSQIPWTPDTAVQQVAC--GHRHTLFLTATGKVYACGSNDYSQLGHD--LPTKRPLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNN--HSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPS 320

HSP 2 Score: 146.747 bits (369), Expect = 2.750e-34
Identity = 116/367 (31.61%), Postives = 184/367 (50.14%), Query Frame = 2

Query: 12431 ASGLEVWSWGHNHRGQ--LGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQP---FPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTED-GEVYSWGDNDEGQLGDGTTTTNSRPRII 13513
            ASG E++ WG    GQ  LGG+E  +I  P           +Q+  G +    ++  G+VYA G  +  +L  G     + P+L+  L++ +++++    G +H LAL + G V +WGD +  +LG        E V  P +V+ LV   ++ IA G +HS A++  GELY+WG   YG+LG  + +D     +P  +  L G  +  +ACG     +  I+K          + +V+ WG  + G+LG         P +++TL   GV  V CG +FS+ LT  G V+T G G Y +LGHG  ++   P  V +L    I  VACG+ H +      G VY++G    GQLG  +T +   P+++
Sbjct:    2 ASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQL--GHDLPTKRPLLIPELQDYVIIQICC--GSRHSLALSDWGQVLSWGDNDCGQLG---HATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISK----------SGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVV 349

HSP 3 Score: 144.821 bits (364), Expect = 1.055e-33
Identity = 120/426 (28.17%), Postives = 195/426 (45.77%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGC------EATSKVKLP-ILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKL-NYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG---HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLA-VTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLV---------SALMDNK-------IAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSV 10615
            ++Y WG     QLG       +  +  ++P   + A+ ++ C    G   +LF +T TGKVY  G +   +LG    T         P  +  L  Y I+++    G RH++AL+  G+  SWG+ D G+LGH +  ++   P+ ++    K VV +ACG++HS A+   G LY+WG   YG+LG     D     +P  + +L    +  +ACG     +  ++    V+ WG  + G+LG    +    P +++ +    V  + CG + S  LT  G V+T G G Y +LGHG   +   P  + +L  + I  +A G  H LA V  RG+VY++G    GQ G  +    M P +V         SAL+ +        I  +  G   S+  T   +D   P    N  P  + ++ +  V
Sbjct:    6 ELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVAC----GHRHTLF-LTATGKVYACGSNDYSQLGHDLPTK-------RPLLIPELQDYVIIQICC--GSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVVIGPWVSPSGSALLQSNDSQVSLVIRQIFSGGDQSIVTTTLFVDKVPPEDFRNYNPKSQILTLTAEV 415

HSP 4 Score: 120.168 bits (300), Expect = 3.424e-26
Identity = 103/336 (30.65%), Postives = 160/336 (47.62%), Query Frame = 2

Query: 12602 VYATGFGNNGRLGIGSTESVQ--TPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXX---XXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            +Y  G  ++G+LG+G  E  Q  TP  +    +  V +VA   G +H L L   G VYA G  + ++LG D+  +       P L+  L    II I  G  HS A+S  G++ +WG    G+LGH    +    PK+V  L    V+ +ACG+            +  + L     ++SWG   YG+LG         C  P+++ TL G  +  + CG   S +++ SG V+ WG+ +  +LG   + +   P ++  L    +  VACG    +  T +G V++ G    GQLG G ++    PR++  L G  I +VACG+ HTLA     G
Sbjct:    7 LYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVAC--GHRHTLFLTATGKVYACGSNDYSQLGHDLPTK------RPLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGN------------NHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRG 322

HSP 5 Score: 89.3521 bits (220), Expect = 8.933e-17
Identity = 60/215 (27.91%), Postives = 103/215 (47.91%), Query Frame = 2

Query: 1367 EIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCL-SNDGAIFTWG 2008
            EIV++   K+ R+L  K  + +I C    +  L+ CG LY   ++         +    +N   D    +  L+L +   +         +H   ++++G V+ WG N  G+LG  D  +R  PT + T     L V+ VACG+E S+ LT  G +++CG    GQLGHG   +  LP  +   +L+G  + Q+A     ++ L  + G ++ +G
Sbjct:  129 EIVQL--PKVVRQLVTK-TVVQIACGNNHSLALTSCGELYSWGSN--------IYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRT--LGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVM--ELMGSTITQVACGNRHTLALVPSRGRVYAFG 328

HSP 6 Score: 88.1965 bits (217), Expect = 1.785e-16
Identity = 53/135 (39.26%), Postives = 75/135 (55.56%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKD-RKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLG---HGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNC 2026
            S H LA+++ GQV SWG N  G+LG    K+  + P ++         V Q+ACG  HSL LT  G++YS G N  GQLG     D+   + P+R+T   L+G+ +  IA  G+ S  +S  GA+F WG   +NC
Sbjct:   99 SRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQL--VTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTT--LLGIPLAAIACGGNHSFLISKSGAVFGWGR--NNC 227

HSP 7 Score: 81.2629 bits (199), Expect = 2.643e-14
Identity = 65/242 (26.86%), Postives = 113/242 (46.69%), Query Frame = 2

Query: 1295 HKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR---PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            H L+            ND  +   ++   RP  +P EL + + I +I C    +  LSD G   +V +  D+  D     H       + ++   V++      V+ +     ++H LA+T  G++YSWG+N  G+LG     D      P  + T     + +  +ACG  HS ++++SG ++  GRN+ GQLG  D  +R  P ++     +GV  + +A     S+ L+N+G +FT G+
Sbjct:   51 HTLFLTATGKVYACGSNDYSQLGHDLPTKRPLLIP-ELQD-YVIIQICCGSRHSLALSDWG---QVLSWGDN--DCGQLGHATDK---EIVQLPKVVRQLVTKTVVQIACG--NNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTL--LGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGV--RFVACGDEFSVFLTNEGGVFTCGA 276

HSP 8 Score: 73.9442 bits (180), Expect = 4.818e-12
Identity = 40/114 (35.09%), Postives = 59/114 (51.75%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++Y WG+ + G+LG G  +D +  T           V+QVACG  H+L LT +G +Y+CG N   QLGH     R L I     +L   ++ QI      S+ LS+ G + +WG
Sbjct:    6 ELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPLLI----PELQDYVIIQICCGSRHSLALSDWGQVLSWG 115

HSP 9 Score: 70.4774 bits (171), Expect = 4.355e-11
Identity = 68/232 (29.31%), Postives = 102/232 (43.97%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKD-RHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-------EIDQIQVHDSTYSVLLKSGSVYTWLK-YCTECNKSDDIQPELDTVLK-YQVDNVSMISKGDGEFYFLDKSGIIRT 2305
            H L +T  G+VY+ G+N   +LG       KRP +I         + Q+ CG  HSL L+  G + S G N  GQLGH   K+   LP  +    L+   V QIA   + S+ L++ G +++WGS   N    L   SP   T  N            +  I    +   ++ KSG+V+ W +  C +   +D+      T LK  +   V  ++ GD    FL   G + T
Sbjct:   51 HTLFLTATGKVYACGSNDYSQLGH--DLPTKRPLLIPELQ--DYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVV--RQLVTKTVVQIACGNNHSLALTSCGELYSWGS---NIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFT 273

HSP 10 Score: 70.0922 bits (170), Expect = 5.752e-11
Identity = 84/320 (26.25%), Postives = 143/320 (44.69%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLF---DKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLF----IRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYR-GVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIH 15082
            K+K  GE  +D GG   E    +  +L +     F           +    +T   +F+ +G L G+AI     ++L     ++K L G+ ++ +DL+     + + + SL+  +  D  E+ +L    S       E          I V   NR  ++D  +++    F+K+         +G   V    ++++F   EL  +V GN+      L+    YR G  S D  I WFWE++ +M+   +  FL F+ G  R+P  +  ++  +  IQ     +P + +LP A+TCF LL LP Y +K  L+ KLL AI 
Sbjct:  741 KIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKYGMFKEYEQSRLLWFADLTFETENMYFL-IGVLCGLAIYNFTIINLPFPLALFKKLLGKPVDLSDLRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKCLKPNGNEIAVTLENRQEFVDLYVDFV---FNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVGNEDYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIP--IQGMKALKLTIQP----TPDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAIQ 1050

HSP 11 Score: 63.929 bits (154), Expect = 4.276e-9
Identity = 39/105 (37.14%), Postives = 53/105 (50.48%), Query Frame = 2

Query: 13268 ASG-EVYTWGKGDYFRLGHGS--DNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            ASG E+Y WG   + +LG G   D  +  P ++       +  VACG  H +  T  G+VY+ G ND  QLG    T   RP +I  L    I ++ CGS H+LA
Sbjct:    2 ASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPT--KRPLLIPELQDYVIIQICCGSRHSLA 104

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Fly
Match: Herc4 (gene:FBgn0035207 transcript:FBtr0310555)

HSP 1 Score: 149.443 bits (376), Expect = 3.530e-35
Identity = 102/329 (31.00%), Postives = 171/329 (51.98%), Query Frame = 2

Query: 9578 KVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRK-----IKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG-DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXX---XXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            ++Y  G +S+G+LG+G   D   E I+ P ++       + +VA   G RH + LT  G+ ++ G  D  +LGH+  L    PR      I   +   ++ + CGS HS A+   G + +WG  D G+LGH  D  +   P++V+ L    VVQ+ACG+    +LALTS   ++SWG   +G+LG       + C  P ++  +    +  I CG   SF ++++G V+ WG+ +  +LG   + +   P Q++ L+   +  +A G    + +T+ G V++ G   +GQ G+G  +  M P +V  LM + I  VACG+ H++A   S
Sbjct:    6 ELYCWGSTSHGQLGLGGIED---EQILTPSQIPWTPDTAVQQVAC--GHRHTLFLTATGKVYACGSNDYSQLGHD--LPTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNN--HSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPS 325

HSP 2 Score: 143.665 bits (361), Expect = 2.505e-33
Identity = 116/370 (31.35%), Postives = 186/370 (50.27%), Query Frame = 2

Query: 12431 ASGLEVWSWGHNHRGQ--LGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLG--IGSTESVQTP-ILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQP---FPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTED-GEVYSWGDNDEGQLGDGTTTTNSRPRII 13513
            ASG E++ WG    GQ  LGG+E  +I  P           +Q+  G +    ++  G+VYA G  +  +LG  + +     +P +L+  L++ +++++    G +H LAL + G V +WGD +  +LG        E V  P +V+ LV   ++ IA G +HS A++  GELY+WG   YG+LG  + +D     +P  +  L G  +  +ACG     +  I+K          + +V+ WG  + G+LG         P +++TL   GV  V CG +FS+ LT  G V+T G G Y +LGHG  ++   P  V +L    I  VACG+ H +      G VY++G    GQLG  +T +   P+++
Sbjct:    2 ASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYVIIQICC--GSRHSLALSDWGQVLSWGDNDCGQLG---HATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISK----------SGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVV 354

HSP 3 Score: 143.665 bits (361), Expect = 2.526e-33
Identity = 119/428 (27.80%), Postives = 199/428 (46.50%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGC------EATSKVKLP-ILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLG--IGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKL-NYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG---HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLA-VTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLV---------SALMDNK-------IAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSV 10615
            ++Y WG     QLG       +  +  ++P   + A+ ++ C    G   +LF +T TGKVY  G +   +LG  + +     +  ++ P+    L  Y I+++    G RH++AL+  G+  SWG+ D G+LGH +  ++   P+ ++    K VV +ACG++HS A+   G LY+WG   YG+LG     D     +P  + +L    +  +ACG     +  ++    V+ WG  + G+LG    +    P +++ +    V  + CG + S  LT  G V+T G G Y +LGHG   +   P  + +L  + I  +A G  H LA V  RG+VY++G    GQ G  +    M P +V         SAL+ +        I  +  G   S+  T   +D   P    N  P  + ++ +  V
Sbjct:    6 ELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVAC----GHRHTLF-LTATGKVYACGSNDYSQLGHDLPTKRPRMSPFLLIPE----LQDYVIIQICC--GSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGN--HSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVVIGPWVSPSGSALLQSNDSQVSLVIRQIFSGGDQSIVTTTLFVDKVPPEDFRNYNPKSQILTLTAEV 420

HSP 4 Score: 117.857 bits (294), Expect = 1.619e-25
Identity = 103/339 (30.38%), Postives = 162/339 (47.79%), Query Frame = 2

Query: 12602 VYATGFGNNGRLGIGSTESVQ--TPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDI---RVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXX---XXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            +Y  G  ++G+LG+G  E  Q  TP  +    +  V +VA   G +H L L   G VYA G  + ++LG D+   R +    +L P L   ++    I I  G  HS A+S  G++ +WG    G+LGH    +    PK+V  L    V+ +ACG+            +  + L     ++SWG   YG+LG         C  P+++ TL G  +  + CG   S +++ SG V+ WG+ +  +LG   + +   P ++  L    +  VACG    +  T +G V++ G    GQLG G ++    PR++  L G  I +VACG+ HTLA     G
Sbjct:    7 LYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVAC--GHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYVI----IQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGN------------NHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRG 327

HSP 5 Score: 89.7373 bits (221), Expect = 7.435e-17
Identity = 60/215 (27.91%), Postives = 103/215 (47.91%), Query Frame = 2

Query: 1367 EIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCL-SNDGAIFTWG 2008
            EIV++   K+ R+L  K  + +I C    +  L+ CG LY   ++         +    +N   D    +  L+L +   +         +H   ++++G V+ WG N  G+LG  D  +R  PT + T     L V+ VACG+E S+ LT  G +++CG    GQLGHG   +  LP  +   +L+G  + Q+A     ++ L  + G ++ +G
Sbjct:  134 EIVQL--PKVVRQLVTK-TVVQIACGNNHSLALTSCGELYSWGSN--------IYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRT--LGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVM--ELMGSTITQVACGNRHTLALVPSRGRVYAFG 333

HSP 6 Score: 88.5817 bits (218), Expect = 1.631e-16
Identity = 53/135 (39.26%), Postives = 75/135 (55.56%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKD-RKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLG---HGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNC 2026
            S H LA+++ GQV SWG N  G+LG    K+  + P ++         V Q+ACG  HSL LT  G++YS G N  GQLG     D+   + P+R+T   L+G+ +  IA  G+ S  +S  GA+F WG   +NC
Sbjct:  104 SRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQL--VTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTT--LLGIPLAAIACGGNHSFLISKSGAVFGWGR--NNC 232

HSP 7 Score: 80.1073 bits (196), Expect = 6.054e-14
Identity = 43/129 (33.33%), Postives = 72/129 (55.81%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR---PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            ++H LA+T  G++YSWG+N  G+LG     D      P  + T     + +  +ACG  HS ++++SG ++  GRN+ GQLG  D  +R  P ++     +GV  + +A     S+ L+N+G +FT G+
Sbjct:  157 NNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTL--LGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGV--RFVACGDEFSVFLTNEGGVFTCGA 281

HSP 8 Score: 72.7886 bits (177), Expect = 9.240e-12
Identity = 38/115 (33.04%), Postives = 59/115 (51.30%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHG-DVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++Y WG+ + G+LG G  +D +  T           V+QVACG  H+L LT +G +Y+CG N   QLGH    K   +   +   +L   ++ QI      S+ LS+ G + +WG
Sbjct:    6 ELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWG 120

HSP 9 Score: 70.0922 bits (170), Expect = 5.760e-11
Identity = 84/320 (26.25%), Postives = 143/320 (44.69%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLF---DKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLF----IRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYR-GVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIH 15082
            K+K  GE  +D GG   E    +  +L +     F           +    +T   +F+ +G L G+AI     ++L     ++K L G+ ++ +DL+     + + + SL+  +  D  E+ +L    S       E          I V   NR  ++D  +++    F+K+         +G   V    ++++F   EL  +V GN+      L+    YR G  S D  I WFWE++ +M+   +  FL F+ G  R+P  +  ++  +  IQ     +P + +LP A+TCF LL LP Y +K  L+ KLL AI 
Sbjct:  745 KIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKYGMFKEYEQSRLLWFADLTFETENMYFL-IGVLCGLAIYNFTIINLPFPLALFKKLLGKPVDLSDLRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKCLKPNGNEIAVTLENRQEFVDLYVDFV---FNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVGNEDYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIP--IQGMKALKLTIQP----TPDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAIQ 1054

HSP 10 Score: 70.0922 bits (170), Expect = 6.537e-11
Identity = 69/235 (29.36%), Postives = 103/235 (43.83%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQ---VKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKD-RHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-------EIDQIQVHDSTYSVLLKSGSVYTWLK-YCTECNKSDDIQPELDTVLK-YQVDNVSMISKGDGEFYFLDKSGIIRT 2305
            H L +T  G+VY+ G+N   +LG       KRP +        LQ   + Q+ CG  HSL L+  G + S G N  GQLGH   K+   LP  +    L+   V QIA   + S+ L++ G +++WGS   N    L   SP   T  N            +  I    +   ++ KSG+V+ W +  C +   +D+      T LK  +   V  ++ GD    FL   G + T
Sbjct:   51 HTLFLTATGKVYACGSNDYSQLGH--DLPTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVV--RQLVTKTVVQIACGNNHSLALTSCGELYSWGS---NIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFT 278

HSP 11 Score: 61.2326 bits (147), Expect = 3.582e-8
Identity = 40/110 (36.36%), Postives = 54/110 (49.09%), Query Frame = 2

Query: 13268 ASG-EVYTWGKGDYFRLGHGS--DNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPR-----IIESLTGKGINRVACGSAHTLA 13573
            ASG E+Y WG   + +LG G   D  +  P ++       +  VACG  H +  T  G+VY+ G ND  QLG    T   RPR     +I  L    I ++ CGS H+LA
Sbjct:    2 ASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHDLPT--KRPRMSPFLLIPELQDYVIIQICCGSRHSLA 109

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Fly
Match: CG9135 (gene:FBgn0031769 transcript:FBtr0079185)

HSP 1 Score: 89.7373 bits (221), Expect = 2.431e-17
Identity = 85/344 (24.71%), Postives = 145/344 (42.15%), Query Frame = 2

Query: 9434 WGLNDKDQLGCEATSKV-KLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNS---------RLKLNY---PRKIKYF------------KGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSL--RDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYY-RLGHGT-DKHIREPMQIEDLKKTKIVHLAVGALHCLAVTD 10378
            +G N   QLG     K+ + P +  AL +L+ V  + G      +T TG VY  G++ +G+ G+G+    T   I  P  +       I    +  G   ++ L   G   ++G  + G+LGHN+         +L  ++   P+K+  +             G ++VD ACG++H+ AI     +Y+WG G +GRLGH +    + P L+K    +      V CGS        T    V   G        +      + P+ ++ +S  N+  I C A +S  ++ +  +  WG    +  LG G   K    P ++  L   KI  + +G  H + + D
Sbjct:  140 FGRNPSGQLGLSQDIKLAEKPTIIPALEQLNIVQAAVGRHHTLFLTDTGTVYACGENKSGQCGVGN----THANIYSPTPINYRGPPII---RIGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGS--------TFSLIVNELGLLFLFGQNKKTGEANMYPKPVQDLSGWNITDIGC-ANTSIMISADDTLIAWGASPTFGELGIGEFQKSSTVPKEVPKLDNIKIPQVTMGYSHTVLLVD 467

HSP 2 Score: 67.781 bits (164), Expect = 1.834e-10
Identity = 42/145 (28.97%), Postives = 67/145 (46.21%), Query Frame = 2

Query: 13214 GAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSD------------NHVRKPEKVAQLNRK------------KIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESL--TGKGINRVACGSAHTL 13570
            G  +I++ CG++FS++L   G ++T+G  +Y +LGH +D            +    P+KV     K            +I+D ACG+ H +       VYSWG    G+LG         PR+++     G+G   V CGS  +L
Sbjct:  220 GPPIIRIGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSL 364

HSP 3 Score: 62.7734 bits (151), Expect = 6.418e-9
Identity = 78/332 (23.49%), Postives = 131/332 (39.46%), Query Frame = 2

Query: 12608 ATGFGNN--GRLGIGS-TESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-----DIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALR-GYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHG--SDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTL 13570
            A GFG N  G+LG+    +  + P ++  LE+  +V+ AV  G  H L L + G VYA G+ +  + G+     +I      +   P +++    AE   I               L+T+G   YG+LGH N D + F   V A +  +H       S     L I K+++  +  V                                 +G  ++   CG+  ++ + +   VY+WG G + RLGH    D  V +  K      +    V CGS   +   E G ++ +G N +      T   N  P+ ++ L+G  I  + C +   +
Sbjct:  137 ALGFGRNPSGQLGLSQDIKLAEKPTIIPALEQLNIVQAAV--GRHHTLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPINYRGPPIIRIGCGAEFSVILDIKG---------SLHTFGLPEYGQLGH-NTDAKYF---VNANKLSFHF----ETSPKKVVLYIEKSKEGHVTPV---------------------------------DGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSLIVNELGLLFLFGQNKK------TGEANMYPKPVQDLSGWNITDIGCANTSIM 410

HSP 4 Score: 58.9214 bits (141), Expect = 9.734e-8
Identity = 41/133 (30.83%), Postives = 65/133 (48.87%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLG-QGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPI-RITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V +   ++H + +    +   +G N SG+LG   D K  ++PTII    +  L + Q A G  H+L LT +G +Y+CG N  GQ G G+    H  I   T  +  G  + +I      S+ L   G++ T+G
Sbjct:  119 VASGPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTIIPALEQ--LNIVQAAVGRHHTLFLTDTGTVYACGENKSGQCGVGNT---HANIYSPTPINYRGPPIIRIGCGAEFSVILDIKGSLHTFG 246

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Zebrafish
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-070718-6])

HSP 1 Score: 999.579 bits (2583), Expect = 0.000e+0
Identity = 605/1321 (45.80%), Postives = 807/1321 (61.09%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L IMD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         ++ ++I+   +L              DT  E  +        ++                ++ G    LQ+    Q+++EEP V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC   R + +L   S LP  F++E   +  +       L  +   +  + E  D   F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP   E L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G +Y+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ SGELYTWGKGRYGRLGHG+ +DQ  PK+VEAL+G+ VI VACGSGDAQTLC+T ++           VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+  + + L NR LLLHH +ELFC  +   DL  +        SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A    +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + +  E E + +P++V +  G+EV L+ + S    ++  NR+ Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+GV+    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FV+QVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL+
Sbjct: 3608 VVVESSHPYIDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTIMDGANRIVSVRSGREWSDWSSELRIPGDELKWKFTSDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EYGQSININRLLG-------------DTEGEARSMSFTGSALAA----------------LVKGLPEALQR----QYEYEEPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCTASRVSVALDKRSPLPRPFLDEVAKKIRE-------LMADHENMNTLHESHD--LFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGELYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGHRVIDVACGSGDAQTLCLTDDD----------MVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPTNAGKLPAQ------VPMEYNHLQEIAIIGLRNRLLLLHHISELFCPCIPMFDLEGRLGETGHGVSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKSPLHISMFRFLGVLLGIAIRTGSPLSLYLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEASAEEFEAMPLPFTVPSACGQEVQLSSKHS---HISLENRSEYVRLAINYRLHEFDEQVSAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGVEPTAPLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVVQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKLVLEEKLKYAIHFCKSIDTDDYARIALS 4798

HSP 2 Score: 489.189 bits (1258), Expect = 2.108e-137
Identity = 271/535 (50.65%), Postives = 352/535 (65.79%), Query Frame = 2

Query: 9323 NSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA---GDVFDIDKNIFQ-KRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTCSQSTE 10915
            N   ED  T + ++S   +   +++   + I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    +++  I  P+++ AL  Y + KVAVHSGGRHA+ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LY+WGLG+YGRLGHGD   +L P+LVK L  ++VVQVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVT+ GQV++WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA   G   D D ++   K N  +    ++           +L+ ++  L G   +   +  +  +LQ++ AR+ V   +  +C    E
Sbjct: 2924 NEEEEDEKTATGSMSRKRLSGLESA---ATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG----LSSGTIPIPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVTT----------PSVHE-----------PVLFQTARDSLGASYLGVPSDSDPSLLSNKLNGVNNVKPNR----------PSLAKILLSLDGNLAKQQALSHVLSSLQIMYARDAVVGALMPSCMMPLE 3420

HSP 3 Score: 376.711 bits (966), Expect = 2.225e-103
Identity = 196/394 (49.75%), Postives = 268/394 (68.02%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEMS 10600
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV++L+ ++V+ VACGS DAQTL LT D  VWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LP+Q    + H++E++
Sbjct: 3950 IYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGELYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPTNAGKLPAQVPMEYNHLQEIA 4338

HSP 4 Score: 357.451 bits (916), Expect = 1.480e-97
Identity = 205/382 (53.66%), Postives = 268/382 (70.16%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+ +G+VYA G   NGRLG+G S+ ++  P  +S L   +V KVAV+SGG+H +AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELY+WG G YGRLGHG+   Q  PK+V+ L G+ V+ VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  TE G+V++WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2954 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLGLSSGTIPIPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVVQVACGSRDAQTLALTDE----------GMVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3321

HSP 5 Score: 281.182 bits (718), Expect = 1.833e-74
Identity = 162/377 (42.97%), Postives = 225/377 (59.68%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKG----KRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  +ALS L    I    K    +T TG VY     S                 + P  + AL    I+K+A H  G+H +AL+ NGE FSWG GD G+LGH     L  P  I  F G    K+VV +ACGS++SAAI   G L+TWG G+YGRLGHG +  +  P LV +L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ +E +   +++++ CG+Q S ALT++GQV+TWGKGD  RLGHGTD+H+R P  ++ L+  ++V +AVG+ HCLA+T+ G+V+SWG ND  Q  +   +   +P  +  L    I  ++CG   S +W++
Sbjct:  412 LQEVIGWGL-----LGWKPYANVNGPIQCKALSNLGVTQIVCSEKGFLILTITGAVYTQNYKST---------------TLAPMLVHALTSRKIMKLAAHPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSNDKLQHFDTLFSNKKQPKALPGLNSKHIVGISCGPGQSFSWSS 768

HSP 6 Score: 256.144 bits (653), Expect = 6.916e-67
Identity = 161/382 (42.15%), Postives = 225/382 (58.90%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV  WG      LG    + +  P+ C+ LS L   QI+  E+   I++I G VY   + +          +   P+LV  L  + ++K+A +  G+H LAL  NG V++WG  +  +LG        E  +        V  +++ IA G ++SAAI+  GEL+TWG+G YGRLGHG+ +DQ  P +V AL+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  +E L+   ++KV CGSQFS+ LT  G+VYTWGKGD  RLGHG+D HVR P+ +  L  K+++D+A GS HC+  TE+GEV+SWG ND+ Q  D   +   +P+ +  L  K I  ++CG   + +W++ S
Sbjct:  414 EVIGWG-----LLGWKPYANVNGPIQCKALSNLGVTQIVCSEKGFLILTITGAVYTQNYKS----------TTLAPMLVHALTSRKIMKLAAHPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSNDKLQHFDTLFSNKKQPKALPGLNSKHIVGISCGPGQSFSWSSCS 770

HSP 7 Score: 189.119 bits (479), Expect = 1.390e-46
Identity = 202/803 (25.16%), Postives = 344/803 (42.84%), Query Frame = 2

Query: 8075 NLKGEFNVVCVNNFGEIFVGDQG-ILSCDGDAI-DGYCNVFWTKISKT-----ISTEKLNIHIFTNPTMSIIIGDEVTFSES-GIRFHSVPAMTSLSNGIVRQIVRLDSEDDDLKIIVDFPNCIGKVCNISDLKLVVKGQHKYQCQACLKSPISLPMYKCKICRNLYLCSNCXXXXXXXXXXXXLNITADEDAKKPKITN--------------GNLFDD-SGKVQTLSVTASVSKSEL-----KQCLSFTNFSLIPQTMSRNIEYTSSNNHCL-IKIAEGYRVHKIFMLISLSEFLLLPSHVIVKKGIKSKKLSTVYRAHVQSLKEDEFIINSSKYYSSGLKLMWLKIYQDKRKHQSTERVXXXXXXXXXXXXRTVFNAVKSFHIQLMENRVDAKSTAISNDILLKTIFSISDKNWSAEDIDTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSK--FKSRIMSKIYVWGLNDKDQLGCEATS-KVKLPILNEALSE--LDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGS--SHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVT 10375
            N++    V C   + E++ GD G ++  D D + D      W +   T     I TE L     ++P+  I IGD+V    S     +   ++T  S G+V+         +   +IVDFP        +S+++LV       +C  C   PI+ P +KC+ C +   C +C    + + +H F  I  +E  + P  +               G L D+ S  V+ LSV++SV+++       +QC   +                S   H + +++     VHK+ M++  ++   +PS V+V  G     L  +   ++        ++N    Y       ++++   + +    +                   A   F     E   D K+             S+S K  S  +        ++ W     ++L     S  + P+ +    + N V+    SK  F      K+Y  G     +LG   +S  + +P    ALS   +  V++  G +    +T  GKV+  G+  +G+LG  S  +        P+ +EAL    I  +A   G  H+ A+T +GE +SWG G+ G+LGH        P+ +K   G RVV VACGS  + + A+   G +++WG GD+G+LG G +     P+ ++ L    V Q+ CG++   +LALT    VW+WG GD+ +LG G       PQ +E +    ++ +  GA    A+TE GQV+ WG  D+ + G+GT    R+P  ++ L+  KI  +A G+ H +A T
Sbjct: 2564 NIQVGMMVRCCRTYEEVYEGDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHTELLGFPPQSSPS-HIKIGDKVRVKPSVTTPKYKWGSVTHRSVGVVKAF-----SANGKDVIVDFPQQSHWTGLLSEMELVPSVHPGVRCDGCQMFPINGPRFKCRSCDDFDFCESCFKTRKHNPRHSFGRI--NEPGQSPTFSGRSGKQLKRHHSSQRGMLIDEWSRVVKNLSVSSSVNQASRLIDCGEQCWQSSG---------------SQGKHWIRLELFPDMLVHKLKMIVDPADSSYMPSLVVVSGGTSLNNLIELKTININPTDTVVSLLNDCTEYHR-----YIEVAIKQCRSSGIDCKIHGLSAVGRVRAEDEDLATVPFLASDNEEEEDEKTAT----------GSMSRKRLSGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLGLSSGTIPIPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDK-----PRLIEALKTKRIRDIAC--GSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQ--FSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWT 3319

HSP 8 Score: 139.813 bits (351), Expect = 1.048e-31
Identity = 91/264 (34.47%), Postives = 133/264 (50.38%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V I+ G     C+T +G++Y  G    GRLG G   D      + PK +EAL  + ++ VA  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 4055 ELYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSED-----QLKPKLVEALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4311

HSP 9 Score: 122.094 bits (305), Expect = 2.041e-26
Identity = 91/265 (34.34%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  ++SWG+ + GKLG G  S C  P+ IE +    V+ I  G   S  +T +G+++TWGKG Y RLGHG  +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3947 SGTIYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGELYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4211

HSP 10 Score: 106.301 bits (264), Expect = 1.406e-21
Identity = 132/518 (25.48%), Postives = 220/518 (42.47%), Query Frame = 2

Query: 4589 MRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEV--------------EILS-------INNSAINAGRKK-------SININDFTSDHLTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGKIRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLLVNDQK-----IESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPN--YQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDGPN-SVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL-------KKSIEDVKNETPSE 5998
            M Q  ++ +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+              ++LS       I    I   RKK       S ++ +   +     PP     +   K    +K  K+  D WQ + N +     G +++ +      V  S +       I +F L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++L  +   +      E  N  E + D LK  + +  FN + L        T   L   SIQ +R  LL    K     ++ +    + N       +G    A+  L++ + L  T+    +   LLL +G+L L Q++LR        LI   C  +      +    S  +  E+ K  +   L +S   L + +K  T V+RG DWK+GDQDGP+  +G V  E   +G +RVQW +   T SYR GK+  YDL+L       + + ED   E  +E
Sbjct: 1458 MDQGKQRSLPKSVIDVCRMVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVSNDLSIVSKLKLLSSQPRWKRITQKLIRDRRKKRVPKKSESADLEECKMEGTNEEPPAPLSPAPVDKKQTTVKSAKQ--DKWQPLLNTI-----GSVQKYRWLR-HSVQGSFSQSSLMSTIVEFSLKEEPLDVEKIRKCLLKQLERAEVRLEGIDTMLK-----LASKNFLLPSVQYAMLCGWQRVIP-----EGTNIGEPLADCLKDVDLIPPFNRMLLEV------TFGKLYAWSIQNVRNILLEASVKFKELGVQPVPLQTITNENPAGPSLGTIPQARFLLAMLHML--TLKHGANSLSLLLNSGILALTQSVLR--------LIGPSCDSSEEELTSVAHGGSATVLEESRKETAPTPLPASGPELAAMMKISTRVMRGPDWKWGDQDGPSPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLAEPPPATQPATEDSDTEDDTE 1940

HSP 11 Score: 100.138 bits (248), Expect = 1.013e-19
Identity = 62/197 (31.47%), Postives = 108/197 (54.82%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL--QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQV-HDSTYSVLL-KSGSVYTWLK 2164
            +  +++ + A+    H LA++  G+V+SWG    G+LG GDT   + PT+I  FS   +  QV  +ACG  +S  +T  G++++ GR + G+LGHG  +D+  P+ +TA   + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +SV L K G VYTW K
Sbjct:  481 TSRKIMKLAAHPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----VEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGK 673

HSP 12 Score: 96.2857 bits (238), Expect = 1.368e-18
Identity = 77/244 (31.56%), Postives = 116/244 (47.54%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G++YSWG    GKLG G+     RP +I++     ++V  +A G  HS  +T SG++Y+ G+   G+LGHGD +D+  P  + A  L G  V  +A      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4038 VAVNSGGKHCLALSSEGELYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVEA--LQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4267

HSP 13 Score: 86.6557 bits (213), Expect = 1.079e-15
Identity = 56/178 (31.46%), Postives = 87/178 (48.88%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H +A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++YS G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3052 HAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKV--LLGHRVVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3225

HSP 14 Score: 86.2705 bits (212), Expect = 1.341e-15
Identity = 57/182 (31.32%), Postives = 88/182 (48.35%), Query Frame = 2

Query: 1472 CGWLYEVNTSSDDVIDTFT-FKHNAINHQFDCLKNDSVLKLWSKN-RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            CG  Y    ++D  + T+    +  + H     +   +L    K  +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +++      L + +V CG + S+ LT+ G +Y+ G+    +LGHG   D H+        L G  V  IAV     + L+ +G + +WGS
Sbjct:  548 CGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQ--DLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHG--TDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGS 725

HSP 15 Score: 82.0333 bits (201), Expect = 2.729e-14
Identity = 49/136 (36.03%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVIDV      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4139 HRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4270

HSP 16 Score: 79.337 bits (194), Expect = 1.609e-13
Identity = 61/211 (28.91%), Postives = 100/211 (47.39%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR+++    + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++YSWG    G+LG GD   + RP ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 3029 IPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVL--LGHRVVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWG 3224

HSP 17 Score: 77.411 bits (189), Expect = 7.567e-13
Identity = 43/136 (31.62%), Postives = 77/136 (56.62%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T +G++Y+WG    G+LG GD++D+ +P +++   + H +V  VAC  G+  +L LT    ++S G    G+LG G      +P++I +  L G+ V ++      S+ L+  GA++TWG
Sbjct: 4089 VVDIAAG--GAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVEAL-QGH-RVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGLGVVKVECGSQFSVALTKSGAVYTWG 4218

HSP 18 Score: 76.2554 bits (186), Expect = 1.491e-12
Identity = 52/197 (26.40%), Postives = 90/197 (45.69%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RV+ V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + ++  G +F WG
Sbjct: 3094 RIRDIACGSSHSAAITSSGELYSWGLG----------EYGRLGHGDNTTQLRPKLVKVLLGHRVVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWG 3276

HSP 19 Score: 76.2554 bits (186), Expect = 1.634e-12
Identity = 69/241 (28.63%), Postives = 107/241 (44.40%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVS----------------MISKGDGEFYFLDKSG 2293
            A T   +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    S L   +VK++AV   G  +M L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +Y+W L         D+   ++P+L   +L ++V  V+                + S GDG+F  L + G
Sbjct: 2948 AATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG-LSSGTIPIPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVVQVACGSRDAQTLALTDEGMVFSWGDGDFGKLGRGG 3183

HSP 20 Score: 65.0846 bits (157), Expect = 3.517e-9
Identity = 43/122 (35.25%), Postives = 66/122 (54.10%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++     ++   V  G +H L L+  G++YS G    G+LGHG+      P R+  S L GV V  IA  G  S C++  G ++TWG
Sbjct: 3993 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGELYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGVEVVDIAAGGAHSACITASGELYTWG 4112

HSP 21 Score: 55.0694 bits (131), Expect = 3.594e-6
Identity = 33/123 (26.83%), Postives = 59/123 (47.97%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   +++     +++ V   + + H LAVTE GQV++WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3205 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQMVEGLRGKKIVHV--AVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3319

HSP 22 Score: 54.6842 bits (130), Expect = 4.543e-6
Identity = 48/179 (26.82%), Postives = 77/179 (43.02%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            S  + AVT  G+VY+ G  T+G+LG G  +     P  I   S   ++   V  G  H++ LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  +++ G +++WG        H  N +   PK+   +  +R         D+    L   G V++W
Sbjct: 2995 SKSLFAVTAEGKVYACGEATNGRLGLGLSSGTIPIPRQISALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVVQVACGSRDAQTLALTDEGMVFSW 3171

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Zebrafish
Match: herc1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-8542])

HSP 1 Score: 453.751 bits (1166), Expect = 1.176e-126
Identity = 348/1108 (31.41%), Postives = 552/1108 (49.82%), Query Frame = 2

Query: 11966 INDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSI---SPVS---------------------TADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWK---KCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLST-RPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL--NRQS------------VMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYAD-KTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETEL--ENLQ--IP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            +N    +  FL  L  ++ +Q+ +E+P V   +QL +S +++ L  LS  ++LD +    PV                       + EWAW   +  T +T E+L    + P  FI         EP  KD L   ++    VS            D Q++ W  SRP+ W    KC         +V+ WG    GQL    G  I VP L    S  + +Q++ G+   F++  +G V A G G+ GRLG G+++ +    ++S L+  +V ++  + G   H +AL  +G V++WGD +  KLG        +    P  +++L   E++ ++ G  HSA ++  G+L+++G G YGRLG GN  ++  P+ V AL G+ V  VACG     TL ++ +           +VW++GDGDYGKLG G       P K++ L G G+ KV CG+QFS+ LT  G VYT+G+     L  G   +  +P++V  L    I DVA G+ H +  +  G+VY+WG N EGQLG G T     P +I +L GK I +++ G  H+ AWT           S   +L L    P   + L   S  +L  R  LL+H+++L  S+   ++L  N QS            V  ++R +L P          +  TM   K +GP+I V R+                                G  C         K +F Q+  ++++    ++ S            LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I SP        ++D F+L+P A  + +   F FLG L+G+AIRT +PL L ++ ++WK L    L+  DL+  D   + +L S+  ++++ +  +N    IP   +   + DGK V + I    +I +  SNR  Y++  I Y++HE D+    +R G+S ++P+PLL+L ++R+LE +VCG   I +  LK +  YR V     ++ WFW+ +++ +NE R LF+RFV GR+RLP   +D+  +  +++V   Y    D LP + TCFF L+LP YSS++++ E+L YAI+ C+SID+D+Y
Sbjct: 3827 LNMAPCMRAFLERLPIMLQEQYAYEKPHVVCGEQLVHSPYMQCLASLSVGLQLDVLLCHPPVPPHMAHCPPEPGSSSIPSHGSWASSEWAWLHCFSTTIKTAEALARGHTFPESFIVPDL-----EPVAKDKLALLMDNSKWVSGM----------DEQVMSWATSRPEDWHLGGKC---------DVFLWGAGRHGQLAEA-GRNILVPTLAPSFS--QAQQVVCGQNCTFVIQANGTVSACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQMVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHG----NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLN--HTLAVSAD---------GMTVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIEDVAVGAEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAAWTAPPVPPRAPGSSVPLQLGLPVCVPPQYSALREVSMEALRARLRLLYHFSDLMYSSWRLLNLSPNNQSCTSRYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRIST-----------------------------RGRKC---------KPIFVQIARQVVK----LNASD---------LRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNAAAEVGYNRDRFLLNPSACLEEHLLQFKFLGILMGVAIRTKKPLDLHLAPMVWKQLCCIPLSLEDLEEVDLLYVQTLNSILHLEDSGITEQNFHEMIPLDSFVGQSADGKMVPI-IPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTARQLEQMVCGLPEISVEVLKKVVRYREVDEQQQLVQWFWQTLDDFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY----DSLPTSQTCFFQLRLPPYSSQSVMAERLRYAINNCRSIDMDNY 4836

HSP 2 Score: 232.646 bits (592), Expect = 8.778e-60
Identity = 144/384 (37.50%), Postives = 215/384 (55.99%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQAL 10570
            +++WG     QL  EA   + +P L  + S+   V    G    F +   G V   G+ S GRLG G+  D+    +I      AL  + + ++    G   H++ALT++GE FSWG+GD GKLGH +  +   PR+I+  +G+ VV ++CG  HSA +   G L+++G GDYGRLG G+T+ +  PE V +L  ++V QVACG     TLA+++D  TVW++GDGD+GKLG G S+    PQK++ +    + ++ CG Q S ALT++G V+T+G+     L  G  ++   P Q+  L    I  +AVGA H L ++  G VY+WG N  GQ G G   +   PTL+SAL    I  ++ G  HS AWTA  +    P  ++
Sbjct: 3990 VFLWGAGRHGQLA-EAGRNILVPTLAPSFSQAQQVVC--GQNCTFVIQANGTVSACGEGSYGRLGQGNSDDLHVLTVI-----SALQGFVVTQMVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLN--HTLAVSADGMTVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIEDVAVGAEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAAWTAPPVPPRAPGSSV 4363

HSP 3 Score: 222.246 bits (565), Expect = 1.302e-56
Identity = 151/379 (39.84%), Postives = 209/379 (55.15%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIK-YFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            ++YVWG N   QL      K+  P L  + S  D  +I  G    F ++  G V   G  S GRLG+G   + +       K+L       I KV+   G   H +A T  GE FSWG+GD GKLGH +     YP+ I+   +GK VV V+ G  HSAA+   G LYTWG GD+GRLGHGD+  R  P LVK + +  V +V+CGS  + T+AL+ D  TVWS+G GD GKLG G ++    P+ +E +    + ++  G+QSS ALT  GQV+ WG G     G      +R P  IE+L  T++V +++G  HCLA++   +VY+WG+N  GQ G G  T  + +P  V  L    I  ++ G+SHS+AWTA   D
Sbjct:  368 EVYVWGSNSSHQLVEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISSDGSVRACGKGSYGRLGLGDSNNQSTL-----KKLTFEPHRAIKKVSSSKGSDGHTLAFTSEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGEVSCGS--SHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELATTRVVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVIGLDGVAIQQISAGTSHSLAWTALPRD 734

HSP 4 Score: 179.874 bits (455), Expect = 7.738e-44
Identity = 138/386 (35.75%), Postives = 219/386 (56.74%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKV--PVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXX-XXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV+ WG N   QL  VEG++ K+  P L    S    + I  G+   F++S DG V A G G+ GRLG+G + +  T   ++    + + KV+ + G   H LA  + G V++WGD +  KLG             P L++  ++ +++  ++AG  HSAA+S  GELYTWG+G +GRLGHG+ + +  P +V+ +   +V  V+CGS  + T+ ++K  D R       +VWS+G GD GKLG G  +    P  +E L+G  + KV  GSQ SL LT++G+VY WG G     G  S+    +P+ + +L   +++D++ G  HC+  + D EVY+WG+N  GQ G G +T   ++P+ +  L G  I +++ G++H+LAWT +
Sbjct:  368 EVYVWGSNSSHQL--VEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISSDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRAIKKVSSSKGSDGHTLAFTSEGEVFSWGDGDYGKLGHG----NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGS--SHTIALSK--DGR-------TVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCG-SSEATALRPKLIEELATTRVVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVIGLDGVAIQQISAGTSHSLAWTAL 731

HSP 5 Score: 95.9005 bits (237), Expect = 1.631e-18
Identity = 82/267 (30.71%), Postives = 134/267 (50.19%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGET-FSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALT 10219
            +++ WG  D  +LG   + + + P   EAL   + V +S G K    VT  GK++  G+   GRLG+G+ ++        P+R+ AL+ + + +VA   G  H +A++ +G T +++G+GD GKLG  +    + P+K+    G  +  VACG+  S A+   G++YT+G      L  G       P+ V +L    +  VA G+    TL+ T D  V++WG    G+LG G ++    P  I  +   N+ QI  G   S A T
Sbjct: 4093 EVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKL-----PERVSALEGHQVGQVAC--GLNHTLAVSADGMTVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIEDVAVGAEHTLTLSSTGD--VYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAAWT 4350

HSP 6 Score: 86.2705 bits (212), Expect = 1.276e-15
Identity = 41/124 (33.06%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG-DIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H  AV+E G++Y+WG    G+LG GD+  R  PT++   S     V +V+CG  H++ L++ G  ++S G    G+LGHGD    + P  + A  L G+ ++++      S+ L++ G ++ WG
Sbjct:  517 HSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS----NVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEA--LQGMFIRKVCAGSQSSLALTSTGQVYAWG 634

HSP 7 Score: 85.5001 bits (210), Expect = 2.472e-15
Identity = 43/117 (36.75%), Postives = 72/117 (61.54%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG 1990
            H +A+TE+G+V+SWG    GKLG G++  ++RP  I+       +V Q++CG +HS ++T  G ++S G    G+LG G+  ++ LP R++A  L G  V Q+A   + ++ +S DG
Sbjct: 4084 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQ--GEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSA--LEGHQVGQVACGLNHTLAVSADG 4196

HSP 8 Score: 79.7221 bits (195), Expect = 1.242e-13
Identity = 59/216 (27.31%), Postives = 97/216 (44.91%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC---GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG-AIFTWGSTFDNCRRHLSN---WSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGD 2263
            H LA T  G+V+SWG    GKLG G++  +K P +I    +  LQ K V C   G  HS  +++ G++Y+ G    G+LGHGD   R++P  +     +G    +++     ++ LS DG  ++++G   +    H      + PK+   +      I ++     +   L  +G VY W    C  C  S+        + +     V  IS GD
Sbjct:  464 HTLAFTSEGEVFSWGDGDYGKLGHGNSSTQKYPKLI----QGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVG----EVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMF--IRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELATTRVVDISIGD 669

HSP 9 Score: 68.5514 bits (166), Expect = 2.906e-10
Identity = 86/309 (27.83%), Postives = 138/309 (44.66%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII---GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVA-VNSGGKHCLALCNNG-LVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPF-PKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTA---SGEVYTWGKGDYFRLGHGSDNHVR 13342
            EV+SWG    G+LG    S  K P L +    L+ + ++    G +    VS DG +Y  G G+ GRLG G + S   P LV     K +  V  V+ G  H +AL  +G  V+++G  ++ KLG          V  P +V++L    I  + AG   S A++ +G++Y WG G    LG G+ +     PK++E L    V+ ++ G     + C+  + D+ +        W          G     I K P K+  L+G  + ++  G+  SL  TA     +V  W +     L   + +H+R
Sbjct:  473 EVFSWGDGDYGKLGHGNSSTQKYPKLIQ--GPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLV-----KDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHG----DTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELATTRVVDISIG----DSHCLALSHDNEV------YAWGNNSMGQCGQGNSTGPITK-PKKVIGLDGVAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLR 757

HSP 10 Score: 68.1662 bits (165), Expect = 3.735e-10
Identity = 39/117 (33.33%), Postives = 63/117 (53.85%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV----DGHQSMCLSNDGAIFTWG 2008
            V+ WG    G+L +   ++   PT+  +FS    Q +QV CG+  + ++  +G + +CG    G+LG G+  D H+   I+A  L G +V Q+      DGH SM L+  G +F+WG
Sbjct: 3990 VFLWGAGRHGQLAEAG-RNILVPTLAPSFS----QAQQVVCGQNCTFVIQANGTVSACGEGSYGRLGQGNSDDLHVLTVISA--LQGFVVTQMVTSCGSDGH-SMALTESGEVFSWG 4098

HSP 11 Score: 66.6254 bits (161), Expect = 1.289e-9
Identity = 44/132 (33.33%), Postives = 71/132 (53.79%), Query Frame = 2

Query: 1664 GQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEE-HSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPK 2056
            G V + G  + G+LGQG++ D    T+I       +     +CG + HS+ LT+SG+++S G    G+LGHG+   +  P +I A  L G  V Q++     S  +++DG +F++G+  D  R  L N S K
Sbjct: 4037 GTVSACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQMVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEA--LQGEEVVQMSCGFKHSAVVTSDGKLFSFGNG-DYGRLGLGNTSNK 4165

HSP 12 Score: 60.4622 bits (145), Expect = 8.604e-8
Identity = 32/130 (24.62%), Postives = 67/130 (51.54%), Query Frame = 2

Query: 1625 NIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +I +     V+E  +VY WG+N+S +L +G  +   +P +  +FS      + +  G+  + +++  G + +CG+   G+LG GD  ++    ++T      I  +      DGH ++  +++G +F+WG
Sbjct:  354 SIQAGEAAMVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFS----DAQTIEAGQYCTFVISSDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRAIKKVSSSKGSDGH-TLAFTSEGEVFSWG 478

HSP 13 Score: 58.5362 bits (140), Expect = 3.784e-7
Identity = 34/102 (33.33%), Postives = 56/102 (54.90%), Query Frame = 2

Query: 1646 LAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIA 1951
            +A+T+ G VY++G +    L +G  ++  RP  +   +   ++   VA G EH+L L+ +GD+Y+ G N  GQLG G       P  I+A  L G  ++QI+
Sbjct: 4243 VALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIE--DVAVGAEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISA--LQGKNIQQIS 4340

HSP 14 Score: 57.7658 bits (138), Expect = 5.201e-7
Identity = 45/156 (28.85%), Postives = 70/156 (44.87%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDR-HLPIRITASDLIGVLVKQIAVDGHQSM---CLSNDGAIFTWG---------STFDNCRRHLSNWSPKI 2059
            S   LA+T  GQVY+WG      LG G ++    RP +I+  +    +V  ++ G+ H L L+   ++Y+ G N MGQ G G+       P ++   D  GV ++QI+     S+    L  D  +  W          STF + R  L  +   I
Sbjct:  618 SQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELATT--RVVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVIGLD--GVAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDGI 767

[Close]

Query: 11966 INDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSI---SPVS---------------------TADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWK---KCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLST-RPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL--NRQS------------VMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYAD-KTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETEL--ENLQ--IP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            +N    +  FL  L  ++ +Q+ +E+P V   +QL +S +++ L  LS  ++LD +    PV                       + EWAW   +  T +T E+L    + P  FI         EP  KD L   ++    VS            D Q++ W  SRP+ W    KC         +V+ WG    GQL    G  I VP L    S  + +Q++ G+   F++  +G V A G G+ GRLG G+++ +    ++S L+  +V ++  + G   H +AL  +G V++WGD +  KLG        +    P  +++L   E++ ++ G  HSA ++  G+L+++G G YGRLG GN  ++  P+ V AL G+ V  VACG     TL ++ +           +VW++GDGDYGKLG G       P K++ L G G+ KV CG+QFS+ LT  G VYT+G+     L  G   +  +P++V  L    I DVA G+ H +  +  G+VY+WG N EGQLG G T     P +I +L GK I +++ G  H+ AWT           S   +L L    P   + L   S  +L  R  LL+H+++L  S+   ++L  N QS            V  ++R +L P          +  TM   K +GP+I V R+                                G  C         K +F Q+  ++++    ++ S            LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I SP        ++D F+L+P A  + +   F FLG L+G+AIRT +PL L ++ ++WK L    L+  DL+  D   + +L S+  ++++ +  +N    IP   +   + DGK V + I    +I +  SNR  Y++  I Y++HE D+    +R G+S ++P+PLL+L ++R+LE +VCG   I +  LK +  YR V     ++ WFW+ +++ +NE R LF+RFV GR+RLP   +D+  +  +++V   Y    D LP + TCFF L+LP YSS++++ E+L YAI+ C+SID+D+Y
Sbjct: 3827 LNMAPCMRAFLERLPIMLQEQYAYEKPHVVCGEQLVHSPYMQCLASLSVGLQLDVLLCHPPVPPHMAHCPPEPGSSSIPSHGSWASSEWAWLHCFSTTIKTAEALARGHTFPESFIVPDL-----EPVAKDKLALLMDNSKWVSGM----------DEQVMSWATSRPEDWHLGGKC---------DVFLWGAGRHGQLAEA-GRNILVPTLAPSFS--QAQQVVCGQNCTFVIQANGTVSACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQMVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHG----NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLN--HTLAVSAD---------GMTVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIEDVAVGAEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAAWTAPPVPPRAPGSSVPLQLGLPVCVPPQYSALREVSMEALRARLRLLYHFSDLMYSSWRLLNLSPNNQSCTSRYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRIST-----------------------------RGRKC---------KPIFVQIARQVVK----LNASD---------LRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNAAAEVGYNRDRFLLNPSACLEEHLLQFKFLGILMGVAIRTKKPLDLHLAPMVWKQLCCIPLSLEDLEEVDLLYVQTLNSILHLEDSGITEQNFHEMIPLDSFVGQSADGKMVPI-IPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTARQLEQMVCGLPEISVEVLKKVVRYREVDEQQQLVQWFWQTLDDFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY----DSLPTSQTCFFQLRLPPYSSQSVMAERLRYAINNCRSIDMDNY 4836

HSP 2 Score: 232.646 bits (592), Expect = 8.778e-60
Identity = 144/384 (37.50%), Postives = 215/384 (55.99%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQAL 10570
            +++WG     QL  EA   + +P L  + S+   V    G    F +   G V   G+ S GRLG G+  D+    +I      AL  + + ++    G   H++ALT++GE FSWG+GD GKLGH +  +   PR+I+  +G+ VV ++CG  HSA +   G L+++G GDYGRLG G+T+ +  PE V +L  ++V QVACG     TLA+++D  TVW++GDGD+GKLG G S+    PQK++ +    + ++ CG Q S ALT++G V+T+G+     L  G  ++   P Q+  L    I  +AVGA H L ++  G VY+WG N  GQ G G   +   PTL+SAL    I  ++ G  HS AWTA  +    P  ++
Sbjct: 3990 VFLWGAGRHGQLA-EAGRNILVPTLAPSFSQAQQVVC--GQNCTFVIQANGTVSACGEGSYGRLGQGNSDDLHVLTVI-----SALQGFVVTQMVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSALEGHQVGQVACGLN--HTLAVSADGMTVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIEDVAVGAEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAAWTAPPVPPRAPGSSV 4363

HSP 3 Score: 222.246 bits (565), Expect = 1.302e-56
Identity = 151/379 (39.84%), Postives = 209/379 (55.15%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIK-YFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            ++YVWG N   QL      K+  P L  + S  D  +I  G    F ++  G V   G  S GRLG+G   + +       K+L       I KV+   G   H +A T  GE FSWG+GD GKLGH +     YP+ I+   +GK VV V+ G  HSAA+   G LYTWG GD+GRLGHGD+  R  P LVK + +  V +V+CGS  + T+AL+ D  TVWS+G GD GKLG G ++    P+ +E +    + ++  G+QSS ALT  GQV+ WG G     G      +R P  IE+L  T++V +++G  HCLA++   +VY+WG+N  GQ G G  T  + +P  V  L    I  ++ G+SHS+AWTA   D
Sbjct:  368 EVYVWGSNSSHQLVEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISSDGSVRACGKGSYGRLGLGDSNNQSTL-----KKLTFEPHRAIKKVSSSKGSDGHTLAFTSEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGEVSCGS--SHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELATTRVVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVIGLDGVAIQQISAGTSHSLAWTALPRD 734

HSP 4 Score: 179.874 bits (455), Expect = 7.738e-44
Identity = 138/386 (35.75%), Postives = 219/386 (56.74%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKV--PVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXX-XXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV+ WG N   QL  VEG++ K+  P L    S    + I  G+   F++S DG V A G G+ GRLG+G + +  T   ++    + + KV+ + G   H LA  + G V++WGD +  KLG             P L++  ++ +++  ++AG  HSAA+S  GELYTWG+G +GRLGHG+ + +  P +V+ +   +V  V+CGS  + T+ ++K  D R       +VWS+G GD GKLG G  +    P  +E L+G  + KV  GSQ SL LT++G+VY WG G     G  S+    +P+ + +L   +++D++ G  HC+  + D EVY+WG+N  GQ G G +T   ++P+ +  L G  I +++ G++H+LAWT +
Sbjct:  368 EVYVWGSNSSHQL--VEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISSDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRAIKKVSSSKGSDGHTLAFTSEGEVFSWGDGDYGKLGHG----NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGS--SHTIALSK--DGR-------TVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCG-SSEATALRPKLIEELATTRVVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVIGLDGVAIQQISAGTSHSLAWTAL 731

HSP 5 Score: 95.9005 bits (237), Expect = 1.631e-18
Identity = 82/267 (30.71%), Postives = 134/267 (50.19%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGET-FSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALT 10219
            +++ WG  D  +LG   + + + P   EAL   + V +S G K    VT  GK++  G+   GRLG+G+ ++        P+R+ AL+ + + +VA   G  H +A++ +G T +++G+GD GKLG  +    + P+K+    G  +  VACG+  S A+   G++YT+G      L  G       P+ V +L    +  VA G+    TL+ T D  V++WG    G+LG G ++    P  I  +   N+ QI  G   S A T
Sbjct: 4093 EVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKL-----PERVSALEGHQVGQVAC--GLNHTLAVSADGMTVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIEDVAVGAEHTLTLSSTGD--VYAWGSNSEGQLGLGHTNHVREPTLISALQGKNIQQISAGRCHSAAWT 4350

HSP 6 Score: 86.2705 bits (212), Expect = 1.276e-15
Identity = 41/124 (33.06%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG-DIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H  AV+E G++Y+WG    G+LG GD+  R  PT++   S     V +V+CG  H++ L++ G  ++S G    G+LGHGD    + P  + A  L G+ ++++      S+ L++ G ++ WG
Sbjct:  517 HSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS----NVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEA--LQGMFIRKVCAGSQSSLALTSTGQVYAWG 634

HSP 7 Score: 85.5001 bits (210), Expect = 2.472e-15
Identity = 43/117 (36.75%), Postives = 72/117 (61.54%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG 1990
            H +A+TE+G+V+SWG    GKLG G++  ++RP  I+       +V Q++CG +HS ++T  G ++S G    G+LG G+  ++ LP R++A  L G  V Q+A   + ++ +S DG
Sbjct: 4084 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQ--GEEVVQMSCGFKHSAVVTSDGKLFSFGNGDYGRLGLGNTSNKKLPERVSA--LEGHQVGQVACGLNHTLAVSADG 4196

HSP 8 Score: 79.7221 bits (195), Expect = 1.242e-13
Identity = 59/216 (27.31%), Postives = 97/216 (44.91%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC---GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG-AIFTWGSTFDNCRRHLSN---WSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGD 2263
            H LA T  G+V+SWG    GKLG G++  +K P +I    +  LQ K V C   G  HS  +++ G++Y+ G    G+LGHGD   R++P  +     +G    +++     ++ LS DG  ++++G   +    H      + PK+   +      I ++     +   L  +G VY W    C  C  S+        + +     V  IS GD
Sbjct:  464 HTLAFTSEGEVFSWGDGDYGKLGHGNSSTQKYPKLI----QGPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVG----EVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEALQGMF--IRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELATTRVVDISIGD 669

HSP 9 Score: 68.5514 bits (166), Expect = 2.906e-10
Identity = 86/309 (27.83%), Postives = 138/309 (44.66%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII---GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVA-VNSGGKHCLALCNNG-LVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPF-PKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTA---SGEVYTWGKGDYFRLGHGSDNHVR 13342
            EV+SWG    G+LG    S  K P L +    L+ + ++    G +    VS DG +Y  G G+ GRLG G + S   P LV     K +  V  V+ G  H +AL  +G  V+++G  ++ KLG          V  P +V++L    I  + AG   S A++ +G++Y WG G    LG G+ +     PK++E L    V+ ++ G     + C+  + D+ +        W          G     I K P K+  L+G  + ++  G+  SL  TA     +V  W +     L   + +H+R
Sbjct:  473 EVFSWGDGDYGKLGHGNSSTQKYPKLIQ--GPLQGKVVVCVSAGYRHSAAVSEDGELYTWGEGDFGRLGHGDSNSRNIPTLV-----KDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHG----DTNRVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELATTRVVDISIG----DSHCLALSHDNEV------YAWGNNSMGQCGQGNSTGPITK-PKKVIGLDGVAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLR 757

HSP 10 Score: 68.1662 bits (165), Expect = 3.735e-10
Identity = 39/117 (33.33%), Postives = 63/117 (53.85%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV----DGHQSMCLSNDGAIFTWG 2008
            V+ WG    G+L +   ++   PT+  +FS    Q +QV CG+  + ++  +G + +CG    G+LG G+  D H+   I+A  L G +V Q+      DGH SM L+  G +F+WG
Sbjct: 3990 VFLWGAGRHGQLAEAG-RNILVPTLAPSFS----QAQQVVCGQNCTFVIQANGTVSACGEGSYGRLGQGNSDDLHVLTVISA--LQGFVVTQMVTSCGSDGH-SMALTESGEVFSWG 4098

HSP 11 Score: 66.6254 bits (161), Expect = 1.289e-9
Identity = 44/132 (33.33%), Postives = 71/132 (53.79%), Query Frame = 2

Query: 1664 GQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEE-HSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPK 2056
            G V + G  + G+LGQG++ D    T+I       +     +CG + HS+ LT+SG+++S G    G+LGHG+   +  P +I A  L G  V Q++     S  +++DG +F++G+  D  R  L N S K
Sbjct: 4037 GTVSACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQMVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEA--LQGEEVVQMSCGFKHSAVVTSDGKLFSFGNG-DYGRLGLGNTSNK 4165

HSP 12 Score: 60.4622 bits (145), Expect = 8.604e-8
Identity = 32/130 (24.62%), Postives = 67/130 (51.54%), Query Frame = 2

Query: 1625 NIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +I +     V+E  +VY WG+N+S +L +G  +   +P +  +FS      + +  G+  + +++  G + +CG+   G+LG GD  ++    ++T      I  +      DGH ++  +++G +F+WG
Sbjct:  354 SIQAGEAAMVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFS----DAQTIEAGQYCTFVISSDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRAIKKVSSSKGSDGH-TLAFTSEGEVFSWG 478

HSP 13 Score: 58.5362 bits (140), Expect = 3.784e-7
Identity = 34/102 (33.33%), Postives = 56/102 (54.90%), Query Frame = 2

Query: 1646 LAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIA 1951
            +A+T+ G VY++G +    L +G  ++  RP  +   +   ++   VA G EH+L L+ +GD+Y+ G N  GQLG G       P  I+A  L G  ++QI+
Sbjct: 4243 VALTKDGNVYTFGQDRLIGLPEGRARNHNRPQQVPALTGVFIE--DVAVGAEHTLTLSSTGDVYAWGSNSEGQLGLGHTNHVREPTLISA--LQGKNIQQIS 4340

HSP 14 Score: 57.7658 bits (138), Expect = 5.201e-7
Identity = 45/156 (28.85%), Postives = 70/156 (44.87%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDR-HLPIRITASDLIGVLVKQIAVDGHQSM---CLSNDGAIFTWG---------STFDNCRRHLSNWSPKI 2059
            S   LA+T  GQVY+WG      LG G ++    RP +I+  +    +V  ++ G+ H L L+   ++Y+ G N MGQ G G+       P ++   D  GV ++QI+     S+    L  D  +  W          STF + R  L  +   I
Sbjct:  618 SQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELATT--RVVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVIGLD--GVAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDGI 767

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Zebrafish
Match: LO018116.1 (pep chromosome:GRCz11:CHR_ALT_CTG6_1_36:37834788:37847878:1 gene:ENSDARG00000115404.1 transcript:ENSDART00000185717.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LO018116.1)

HSP 1 Score: 356.295 bits (913), Expect = 2.821e-108
Identity = 192/378 (50.79%), Postives = 259/378 (68.52%), Query Frame = 2

Query: 14030 KTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPD--------KDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            K+VFGQ+  K+   +             PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P+        +DCF+L+P A    +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + +  E E + +P++V +  G+EV L+ + S    ++  NR+ Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+GV+    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FV+QVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL+
Sbjct:   60 KSVFGQMCAKMSSFS-------------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKSPLHISMFRFLGVLLGIAIRTGSPLSLYLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEASAEEFEAMPLPFTVPSACGQEVQLSSKHS---HISLENRSEYVRLAINYRLHEFDEQVSAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGVEPTAPLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVVQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKLVLEEKLKYAIHFCKSIDTDDYARIALS 421

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Zebrafish
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-070718-6])

HSP 1 Score: 279.641 bits (714), Expect = 1.028e-77
Identity = 162/377 (42.97%), Postives = 225/377 (59.68%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKG----KRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  +ALS L    I    K    +T TG VY     S                 + P  + AL    I+K+A H  G+H +AL+ NGE FSWG GD G+LGH     L  P  I  F G    K+VV +ACGS++SAAI   G L+TWG G+YGRLGHG +  +  P LV +L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ +E +   +++++ CG+Q S ALT++GQV+TWGKGD  RLGHGTD+H+R P  ++ L+  ++V +AVG+ HCLA+T+ G+V+SWG ND  Q  +   +   +P  +  L    I  ++CG   S +W++
Sbjct:  412 LQEVIGWGL-----LGWKPYANVNGPIQCKALSNLGVTQIVCSEKGFLILTITGAVYTQNYKS---------------TTLAPMLVHALTSRKIMKLAAHPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSNDKLQHFDTLFSNKKQPKALPGLNSKHIVGISCGPGQSFSWSS 768

HSP 2 Score: 252.677 bits (644), Expect = 9.996e-69
Identity = 158/372 (42.47%), Postives = 222/372 (59.68%), Query Frame = 2

Query: 12473 GQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            G LG    + +  P+ C+ LS L   QI+  E+   I++I G VY   + +          +   P+LV  L  + ++K+A +  G+H LAL  NG V++WG  +  +LG        E  +        V  +++ IA G ++SAAI+  GEL+TWG+G YGRLGHG+ +DQ  P +V AL+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  +E L+   ++KV CGSQFS+ LT  G+VYTWGKGD  RLGHG+D HVR P+ +  L  K+++D+A GS HC+  TE+GEV+SWG ND+ Q  D   +   +P+ +  L  K I  ++CG   + +W++ S
Sbjct:  419 GLLGWKPYANVNGPIQCKALSNLGVTQIVCSEKGFLILTITGAVYTQNYKS----------TTLAPMLVHALTSRKIMKLAAHPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGSNDKLQHFDTLFSNKKQPKALPGLNSKHIVGISCGPGQSFSWSSCS 770

HSP 3 Score: 99.7525 bits (247), Expect = 6.332e-20
Identity = 62/197 (31.47%), Postives = 108/197 (54.82%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL--QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQV-HDSTYSVLL-KSGSVYTWLK 2164
            +  +++ + A+    H LA++  G+V+SWG    G+LG GDT   + PT+I  FS   +  QV  +ACG  +S  +T  G++++ GR + G+LGHG  +D+  P+ +TA   + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +SV L K G VYTW K
Sbjct:  481 TSRKIMKLAAHPDGQHYLALSVNGEVFSWGCGDGGRLGHGDTTYLEEPTMISVFSGRPVGKQVVHIACGSTYSAAITADGELHTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLV----EKLQDLDIVKVCCGSQFSVALTKDGQVYTWGK 673

HSP 4 Score: 85.5001 bits (210), Expect = 1.348e-15
Identity = 49/136 (36.03%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +++      L + +V CG + S+ LT+ G +Y+ G+    +LGHG   D H+        L G  V  IAV     + L+ +G + +WGS
Sbjct:  594 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQ--DLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHG--TDEHVRYPKLLDSLQGKRVVDIAVGSTHCLALTEEGEVHSWGS 725

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 1007.67 bits (2604), Expect = 0.000e+0
Identity = 599/1321 (45.34%), Postives = 806/1321 (61.01%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L IMD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L    ++++ ++           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP +F++E   +  +       L  +   + A  E  D   F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ +GELYTWGKGRYGRLGHG+ +DQ  PK+VEAL+GY VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL  +        S+  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+   +             PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A  T +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   I Y++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFW++ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3509 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTIMDGANRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EFGQSININRLLGDGETETRAMS-----------FSGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRQFLDEVAKKIRE-------LMADNENMNAGHESHD--TFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPANAGKLPSQ------VPMEYNHLQEIMIIALRNRLLLLHHISELFCPCIPMFDLEGRLDESGQGPSIGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKMASFS-------------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKTTLHMNMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMILPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAIGYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPTASLIQWFWDVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4699

HSP 2 Score: 482.641 bits (1241), Expect = 2.946e-135
Identity = 265/481 (55.09%), Postives = 327/481 (67.98%), Query Frame = 2

Query: 9263 CNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKS-------------RIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            C ++  + +   LN L  Q+ +  ED  T     S+N  E+ D +   S              I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA
Sbjct: 2790 CRSSGIDCKIHELN-LVGQIRAEDEDMATVPFLASDNDEEDDDKASTGSFVRKKTAGLESTATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDALGA 3244

HSP 3 Score: 379.407 bits (973), Expect = 5.857e-104
Identity = 198/393 (50.38%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV++L+ Y+V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V ++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LPSQ    + H++E+
Sbjct: 3851 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPANAGKLPSQVPMEYNHLQEI 4238

HSP 4 Score: 352.443 bits (903), Expect = 8.258e-96
Identity = 206/382 (53.93%), Postives = 265/382 (69.37%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+ +G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G  V +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P ++  L G+ I RVACGS+H++AWTTV
Sbjct: 2855 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTV 3222

HSP 5 Score: 259.996 bits (663), Expect = 7.418e-68
Identity = 153/373 (41.02%), Postives = 221/373 (59.25%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  EAL+ L    ++   K    ++R GK+Y    ++N                +GP+ ++ L    IVK+A H  G+H +AL+   E FSWG GD       S L            GK+V+ +ACGS++SAAI   G LYTWG G+YGRLGHG +  +  P LV  L+  KVV V+CGS DAQTL++T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +++++ CG+Q S A+T++GQV++WGKGD  RLGHGT++H+R P  +  L+  K+V +AVG+ HCLA+T+ G+VYSWG ND  Q  +        P+++  L    I  ++CG + S AW++
Sbjct:  328 LQEVISWGL-----LGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN---------------TLGPQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDVLFCPLVSALSGKQ-------TGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSS 673

HSP 6 Score: 249.595 bits (636), Expect = 9.396e-65
Identity = 167/386 (43.26%), Postives = 223/386 (57.77%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSL----VKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV SWG      LG    + +  P+ CE L+ L   Q+   E+   I+S +G++Y   + NN  LG         P LV GL  + +VK+A +  G+H LAL     +++WG                 DVL   LV +L       ++I IA G ++SAAI+  GELYTWG+G YGRLGHG+ +DQ  P +V  L+G  V+ V+CGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   ++KV CGSQFS+ +T  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK++DVA GS HC+  TE GEVYSWG ND+ Q  D        P ++  L  K I  ++CG A + AW++ S
Sbjct:  330 EVISWG-----LLGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCG---------------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCS 675

HSP 7 Score: 138.658 bits (348), Expect = 3.137e-31
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L   + V I+ G     C+T  G++Y  G    GRLG G   D      + PK +EAL  Y ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  V  V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 3956 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSED-----QLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4212

HSP 8 Score: 125.561 bits (314), Expect = 2.902e-27
Identity = 92/303 (30.36%), Postives = 154/303 (50.83%), Query Frame = 2

Query: 9653 IIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVAC--GSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYK----VVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGA--QSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            + GP + EAL    + +VA     +  + L++NG+ ++    ++  LG         P+ ++    + +V +A      H  A+     L++WG GD            L   LV +L   +    V+ +ACGS    + A+T+D  +++WG G++G+LG G S    +P  +  +    V+ + CG+    + ++TENGQVW+WG GDY +LG G     + P  IE L+   IV +  G+   +A+T  GQVYSWG  D+ + G+GT  +   P +++ L   K+  VA GS+H +A T S
Sbjct:  345 VSGPIQCEALANLGVTQVACAE--KCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDV-----------LFCPLVSALSGKQTGKQVIHIACGS--TYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTES 622

HSP 9 Score: 124.02 bits (310), Expect = 8.127e-27
Identity = 92/265 (34.72%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +  + V+ I  G   S  +T  G+++TWGKG Y RLGHG  +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3848 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKS 4112

HSP 10 Score: 112.849 bits (281), Expect = 1.889e-23
Identity = 175/743 (23.55%), Postives = 299/743 (40.24%), Query Frame = 2

Query: 4529 LNLVALVKHV---NLCEELANH---IMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAY----------------------------------------------KAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQ--LVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTL-ITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKL 6556
            L L  L+KH    N+   L +H    + Q   + +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RWK I                                                K  + +K PK   D WQ + + V      K ++ N       V  +       G I +F+L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++   FC    +    E  N +E + D LK  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + N L  T        +LLL +G+L L QT+LR        LI   C+++ +     VM  S  +  E+ K  +   L +S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L         E P     +++ +D                     ++++  +E E++  + +        P+ L+L S   L+QA+ +         V+     S+       LL  L+   ++  +     S K +Y+EQ   WC   F+ ++ I        +   WI L +K  E     S+  ++  QIL +++L+ +
Sbjct: 1334 LLLCCLLKHEDLGNIALSLVHHGALSVEQVKHKTLPKSVVDVCRVVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIVSKLKL-----------LSSVP---RWKRIVQKIIREKRKKKVPKKSESADVDDTKLGNEEGEMEESCVVPSSPVSVDKKTVPIKSPK---DKWQPLLSTVAGVHKYKWLKHN-------VQGTYPQSALLGTIVEFVLKEEPVDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LAAKTFLLPSVQYAM---FCGWQRL--VPEGTNISEPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNTLMDASSCFKEMGIQPVPLQTITNENPSGPSLGTIPQARFMLVMVNML--TCQHGAKSLNLLLNSGMLALTQTILR--------LIGPSCENSEDDSSVCVMGASATVLEESRKETTPVQLPASGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKL--------TEPPP--ATQAMAED---------------------SDTEDDSEGEQIDKNLH--------PTSLMLMSTVNLLQALCLSA------GVNAEVMQSETTRTLCGLLRMLVESGTMDKT--STQSNKLVYKEQHKSWCTLGFIRSIAIMPQMCSTLSMPQWISLLMKIVEGPESFSAA-SLQRQILAVRLLQAV 1977

HSP 11 Score: 112.464 bits (280), Expect = 2.328e-23
Identity = 66/166 (39.76%), Postives = 90/166 (54.22%), Query Frame = 2

Query: 13214 GAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTR-----PTSCNLLENKSAVSL 13690
            G  VI + CGS +S  +TA GE+YTWG+G+Y RLGHGS      P  V  L   K++DV+CGS     +  TE+G+V+SWGD D G+LG G +     P++IE L    I +V CGS  ++A  T  G      +  +QRL   T      P   N L+ K  V +
Sbjct:  445 GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIA-ITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDV 609

HSP 12 Score: 108.612 bits (270), Expect = 3.781e-22
Identity = 87/265 (32.83%), Postives = 132/265 (49.81%), Query Frame = 2

Query: 12515 VLCEHLSALRPRQIIGGEQSLFI---------VSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            + C  +SAL  +Q   G+Q + I         ++ DG +Y  G GN GRLG GS+E    P+LV+GL+   VV V+  SG    L++  NG V++WGD +  KLG     + G D   TP L++ L   +I+ +  G   S AI++ G++Y+WGKG   RLGHG  +   +PKI+  L+G  V+ VA GS    T C+   E           V+SWG  D  +          +P  +  L+   ++ + CG   S   ++  E
Sbjct:  431 LFCPLVSALSGKQT--GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLG-----RGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGS----THCLALTESGE--------VYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCSE 676

HSP 13 Score: 97.4413 bits (241), Expect = 8.565e-19
Identity = 77/243 (31.69%), Postives = 114/243 (46.91%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++      +V  +A G  HS  +T +G++Y+ G+   G+LGHGD +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++       +++      S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 3939 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEA--LQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTGVGVTKVE----CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4168

HSP 14 Score: 85.8853 bits (211), Expect = 2.899e-15
Identity = 48/142 (33.80%), Postives = 76/142 (53.52%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +V+DV      +  L+VTE GQV+SWG    GKLG+G +   K P +I+      L + +V CG + S+ +T+ G +YS G+    +LGHG   + H+      + L G  V  +AV     + L+  G +++WGS  D C+
Sbjct:  499 KVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHG--TEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSN-DQCQ 635

HSP 15 Score: 84.3445 bits (207), Expect = 7.464e-15
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 2953 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGK 3126

HSP 16 Score: 81.2629 bits (199), Expect = 7.212e-14
Identity = 43/136 (31.62%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T AG++Y+WG    G+LG GD++D+ +P +++       +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L GV V ++      S+ L+  GA++TWG
Sbjct: 3990 VVDIAAG--GAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQ--GYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGVGVTKVECGSQFSVALTKSGAVYTWG 4119

HSP 17 Score: 80.4925 bits (197), Expect = 1.087e-13
Identity = 47/135 (34.81%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   + V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4041 RVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4171

HSP 18 Score: 76.6406 bits (187), Expect = 1.809e-12
Identity = 59/211 (27.96%), Postives = 99/211 (46.92%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 2930 IPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQAVCQIECGAQFSLALTKSGVVWTWG 3125

HSP 19 Score: 75.485 bits (184), Expect = 3.973e-12
Identity = 52/197 (26.40%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 2995 RIRDIACGSSHSAAITSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWG 3177

HSP 20 Score: 73.1738 bits (178), Expect = 2.049e-11
Identity = 52/169 (30.77%), Postives = 79/169 (46.75%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +YTW
Sbjct: 2855 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYTW 3018

HSP 21 Score: 70.0922 bits (170), Expect = 1.381e-10
Identity = 61/254 (24.02%), Postives = 117/254 (46.06%), Query Frame = 2

Query: 1424 IKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            + ++ C+     +LS  G LY           T  + +N +  Q        V  L S+N ++ + A+    H LA++   +++SWG             D     ++   S  +   QV  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D+ +P+ +T    + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ + K G VY+W K
Sbjct:  359 VTQVACAEKCFLILSRNGKLY-----------TQAYNNNTLGPQL-------VQGLASRN-IVKIAAHPDGQHYLALSATSELFSWGCG-----------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGK 578

HSP 22 Score: 63.5438 bits (153), Expect = 1.300e-8
Identity = 45/124 (36.29%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G  V  IA  G  S C++  G ++TWG
Sbjct: 3894 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGTEVVDIAAGGAHSACITAAGELYTWG 4013

HSP 23 Score: 57.7658 bits (138), Expect = 8.462e-7
Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   V++     +++ V   + + H LAVT+AGQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3106 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLE--GQKITRVACGSSHSVAWT 3220

HSP 24 Score: 54.299 bits (129), Expect = 9.909e-6
Identity = 39/126 (30.95%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VY+ G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  +++ G ++TWG
Sbjct: 2896 SKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAAITSSGELYTWG 3019

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 1007.28 bits (2603), Expect = 0.000e+0
Identity = 599/1321 (45.34%), Postives = 806/1321 (61.01%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L IMD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L    ++++ ++           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP +F++E   +  +       L  +   + A  E  D   F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ +GELYTWGKGRYGRLGHG+ +DQ  PK+VEAL+GY VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL  +        S+  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+   +             PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A  T +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   I Y++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFW++ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3587 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTIMDGANRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EFGQSININRLLGDGETETRAMS-----------FSGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRQFLDEVAKKIRE-------LMADNENMNAGHESHD--TFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPANAGKLPSQ------VPMEYNHLQEIMIIALRNRLLLLHHISELFCPCIPMFDLEGRLDESGQGPSIGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKMASFS-------------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKTTLHMNMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMILPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAIGYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPTASLIQWFWDVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4777

HSP 2 Score: 482.641 bits (1241), Expect = 3.659e-135
Identity = 265/481 (55.09%), Postives = 327/481 (67.98%), Query Frame = 2

Query: 9263 CNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKS-------------RIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            C ++  + +   LN L  Q+ +  ED  T     S+N  E+ D +   S              I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA
Sbjct: 2868 CRSSGIDCKIHELN-LVGQIRAEDEDMATVPFLASDNDEEDDDKASTGSFVRKKTAGLESTATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDALGA 3322

HSP 3 Score: 379.407 bits (973), Expect = 6.066e-104
Identity = 198/393 (50.38%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV++L+ Y+V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V ++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LPSQ    + H++E+
Sbjct: 3929 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPANAGKLPSQVPMEYNHLQEI 4316

HSP 4 Score: 352.443 bits (903), Expect = 8.472e-96
Identity = 206/382 (53.93%), Postives = 265/382 (69.37%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+ +G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G  V +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P ++  L G+ I RVACGS+H++AWTTV
Sbjct: 2933 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTV 3300

HSP 5 Score: 259.996 bits (663), Expect = 7.398e-68
Identity = 153/373 (41.02%), Postives = 221/373 (59.25%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  EAL+ L    ++   K    ++R GK+Y    ++N                +GP+ ++ L    IVK+A H  G+H +AL+   E FSWG GD       S L            GK+V+ +ACGS++SAAI   G LYTWG G+YGRLGHG +  +  P LV  L+  KVV V+CGS DAQTL++T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +++++ CG+Q S A+T++GQV++WGKGD  RLGHGT++H+R P  +  L+  K+V +AVG+ HCLA+T+ G+VYSWG ND  Q  +        P+++  L    I  ++CG + S AW++
Sbjct:  409 LQEVISWGL-----LGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN---------------TLGPQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDVLFCPLVSALSGKQ-------TGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSS 754

HSP 6 Score: 249.595 bits (636), Expect = 9.525e-65
Identity = 167/386 (43.26%), Postives = 223/386 (57.77%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSL----VKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV SWG      LG    + +  P+ CE L+ L   Q+   E+   I+S +G++Y   + NN  LG         P LV GL  + +VK+A +  G+H LAL     +++WG                 DVL   LV +L       ++I IA G ++SAAI+  GELYTWG+G YGRLGHG+ +DQ  P +V  L+G  V+ V+CGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   ++KV CGSQFS+ +T  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK++DVA GS HC+  TE GEVYSWG ND+ Q  D        P ++  L  K I  ++CG A + AW++ S
Sbjct:  411 EVISWG-----LLGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCG---------------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCS 756

HSP 7 Score: 138.658 bits (348), Expect = 2.868e-31
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L   + V I+ G     C+T  G++Y  G    GRLG G   D      + PK +EAL  Y ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  V  V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 4034 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSED-----QLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4290

HSP 8 Score: 125.561 bits (314), Expect = 3.084e-27
Identity = 92/303 (30.36%), Postives = 154/303 (50.83%), Query Frame = 2

Query: 9653 IIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVAC--GSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYK----VVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGA--QSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            + GP + EAL    + +VA     +  + L++NG+ ++    ++  LG         P+ ++    + +V +A      H  A+     L++WG GD            L   LV +L   +    V+ +ACGS    + A+T+D  +++WG G++G+LG G S    +P  +  +    V+ + CG+    + ++TENGQVW+WG GDY +LG G     + P  IE L+   IV +  G+   +A+T  GQVYSWG  D+ + G+GT  +   P +++ L   K+  VA GS+H +A T S
Sbjct:  426 VSGPIQCEALANLGVTQVACAE--KCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDV-----------LFCPLVSALSGKQTGKQVIHIACGS--TYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTES 703

HSP 9 Score: 124.02 bits (310), Expect = 8.351e-27
Identity = 92/265 (34.72%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +  + V+ I  G   S  +T  G+++TWGKG Y RLGHG  +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3926 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKS 4190

HSP 10 Score: 112.464 bits (280), Expect = 2.294e-23
Identity = 66/166 (39.76%), Postives = 90/166 (54.22%), Query Frame = 2

Query: 13214 GAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTR-----PTSCNLLENKSAVSL 13690
            G  VI + CGS +S  +TA GE+YTWG+G+Y RLGHGS      P  V  L   K++DV+CGS     +  TE+G+V+SWGD D G+LG G +     P++IE L    I +V CGS  ++A  T  G      +  +QRL   T      P   N L+ K  V +
Sbjct:  526 GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIA-ITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDV 690

HSP 11 Score: 109.383 bits (272), Expect = 1.875e-22
Identity = 139/544 (25.55%), Postives = 225/544 (41.36%), Query Frame = 2

Query: 4529 LNLVALVKHV---NLCEELANH---IMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAY----------------------------------------------KAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQ--LVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKK 5962
            L L  L+KH    N+   L +H    + Q   + +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RWK I                                                K  + +K PK   D WQ + + V      K ++ N       V  +       G I +F+L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++   FC    +    E  N +E + D LK  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + N L  T        +LLL +G+L L QT+LR        LI   C+++ +     VM  S  +  E+ K  +   L +S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L +
Sbjct: 1415 LLLCCLLKHEDLGNIALSLVHHGALSVEQVKHKTLPKSVVDVCRVVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIVSKLKL-----------LSSVP---RWKRIVQKIIREKRKKKVPKKSESADVDDTKLGNEEGEMEESCVVPSSPVSVDKKTVPIKSPK---DKWQPLLSTVAGVHKYKWLKHN-------VQGTYPQSALLGTIVEFVLKEEPVDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LAAKTFLLPSVQYAM---FCGWQRL--VPEGTNISEPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNTLMDASSCFKEMGIQPVPLQTITNENPSGPSLGTIPQARFMLVMVNML--TCQHGAKSLNLLLNSGMLALTQTILR--------LIGPSCENSEDDSSVCVMGASATVLEESRKETTPVQLPASGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLTE 1907

HSP 12 Score: 108.612 bits (270), Expect = 3.483e-22
Identity = 87/265 (32.83%), Postives = 132/265 (49.81%), Query Frame = 2

Query: 12515 VLCEHLSALRPRQIIGGEQSLFI---------VSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            + C  +SAL  +Q   G+Q + I         ++ DG +Y  G GN GRLG GS+E    P+LV+GL+   VV V+  SG    L++  NG V++WGD +  KLG     + G D   TP L++ L   +I+ +  G   S AI++ G++Y+WGKG   RLGHG  +   +PKI+  L+G  V+ VA GS    T C+   E           V+SWG  D  +          +P  +  L+   ++ + CG   S   ++  E
Sbjct:  512 LFCPLVSALSGKQT--GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLG-----RGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGS----THCLALTESGE--------VYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCSE 757

HSP 13 Score: 97.4413 bits (241), Expect = 7.695e-19
Identity = 77/243 (31.69%), Postives = 114/243 (46.91%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++      +V  +A G  HS  +T +G++Y+ G+   G+LGHGD +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++       +++      S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4017 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEA--LQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTGVGVTKVE----CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4246

HSP 14 Score: 85.8853 bits (211), Expect = 2.518e-15
Identity = 48/142 (33.80%), Postives = 76/142 (53.52%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +V+DV      +  L+VTE GQV+SWG    GKLG+G +   K P +I+      L + +V CG + S+ +T+ G +YS G+    +LGHG   + H+      + L G  V  +AV     + L+  G +++WGS  D C+
Sbjct:  580 KVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHG--TEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSN-DQCQ 716

HSP 15 Score: 84.3445 bits (207), Expect = 6.874e-15
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3031 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGK 3204

HSP 16 Score: 81.2629 bits (199), Expect = 6.108e-14
Identity = 43/136 (31.62%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T AG++Y+WG    G+LG GD++D+ +P +++       +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L GV V ++      S+ L+  GA++TWG
Sbjct: 4068 VVDIAAG--GAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQ--GYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGVGVTKVECGSQFSVALTKSGAVYTWG 4197

HSP 17 Score: 80.8777 bits (198), Expect = 9.282e-14
Identity = 47/135 (34.81%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   + V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4119 RVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4249

HSP 18 Score: 76.6406 bits (187), Expect = 1.666e-12
Identity = 59/211 (27.96%), Postives = 99/211 (46.92%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 3008 IPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQAVCQIECGAQFSLALTKSGVVWTWG 3203

HSP 19 Score: 75.485 bits (184), Expect = 3.689e-12
Identity = 52/197 (26.40%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3073 RIRDIACGSSHSAAITSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWG 3255

HSP 20 Score: 73.1738 bits (178), Expect = 1.951e-11
Identity = 52/169 (30.77%), Postives = 79/169 (46.75%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +YTW
Sbjct: 2933 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYTW 3096

HSP 21 Score: 70.4774 bits (171), Expect = 1.272e-10
Identity = 61/254 (24.02%), Postives = 117/254 (46.06%), Query Frame = 2

Query: 1424 IKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            + ++ C+     +LS  G LY           T  + +N +  Q        V  L S+N ++ + A+    H LA++   +++SWG             D     ++   S  +   QV  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D+ +P+ +T    + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ + K G VY+W K
Sbjct:  440 VTQVACAEKCFLILSRNGKLY-----------TQAYNNNTLGPQL-------VQGLASRN-IVKIAAHPDGQHYLALSATSELFSWGCG-----------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGK 659

HSP 22 Score: 63.929 bits (154), Expect = 1.177e-8
Identity = 45/124 (36.29%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G  V  IA  G  S C++  G ++TWG
Sbjct: 3972 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGTEVVDIAAGGAHSACITAAGELYTWG 4091

HSP 23 Score: 57.7658 bits (138), Expect = 8.980e-7
Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   V++     +++ V   + + H LAVT+AGQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3184 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLE--GQKITRVACGSSHSVAWT 3298

HSP 24 Score: 54.299 bits (129), Expect = 8.674e-6
Identity = 39/126 (30.95%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VY+ G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  +++ G ++TWG
Sbjct: 2974 SKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAAITSSGELYTWG 3097

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 1006.9 bits (2602), Expect = 0.000e+0
Identity = 599/1321 (45.34%), Postives = 806/1321 (61.01%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L IMD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L    ++++ ++           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP +F++E   +  +       L  +   + A  E  D   F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ +GELYTWGKGRYGRLGHG+ +DQ  PK+VEAL+GY VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL  +        S+  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+   +             PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A  T +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   I Y++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFW++ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3591 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTIMDGANRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EFGQSININRLLGDGETETRAMS-----------FSGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRQFLDEVAKKIRE-------LMADNENMNAGHESHD--TFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPANAGKLPSQ------VPMEYNHLQEIMIIALRNRLLLLHHISELFCPCIPMFDLEGRLDESGQGPSIGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKMASFS-------------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKTTLHMNMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMILPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAIGYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPTASLIQWFWDVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4781

HSP 2 Score: 482.256 bits (1240), Expect = 4.258e-135
Identity = 265/481 (55.09%), Postives = 327/481 (67.98%), Query Frame = 2

Query: 9263 CNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKS-------------RIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            C ++  + +   LN L  Q+ +  ED  T     S+N  E+ D +   S              I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA
Sbjct: 2872 CRSSGIDCKIHELN-LVGQIRAEDEDMATVPFLASDNDEEDDDKASTGSFVRKKTAGLESTATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDALGA 3326

HSP 3 Score: 379.022 bits (972), Expect = 7.298e-104
Identity = 198/393 (50.38%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV++L+ Y+V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V ++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LPSQ    + H++E+
Sbjct: 3933 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPANAGKLPSQVPMEYNHLQEI 4320

HSP 4 Score: 352.058 bits (902), Expect = 9.373e-96
Identity = 206/382 (53.93%), Postives = 265/382 (69.37%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+ +G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G  V +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P ++  L G+ I RVACGS+H++AWTTV
Sbjct: 2937 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTV 3304

HSP 5 Score: 259.61 bits (662), Expect = 8.182e-68
Identity = 153/373 (41.02%), Postives = 221/373 (59.25%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  EAL+ L    ++   K    ++R GK+Y    ++N                +GP+ ++ L    IVK+A H  G+H +AL+   E FSWG GD       S L            GK+V+ +ACGS++SAAI   G LYTWG G+YGRLGHG +  +  P LV  L+  KVV V+CGS DAQTL++T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +++++ CG+Q S A+T++GQV++WGKGD  RLGHGT++H+R P  +  L+  K+V +AVG+ HCLA+T+ G+VYSWG ND  Q  +        P+++  L    I  ++CG + S AW++
Sbjct:  409 LQEVISWGL-----LGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN---------------TLGPQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDVLFCPLVSALSGKQ-------TGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSS 754

HSP 6 Score: 249.595 bits (636), Expect = 1.027e-64
Identity = 167/386 (43.26%), Postives = 223/386 (57.77%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSL----VKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV SWG      LG    + +  P+ CE L+ L   Q+   E+   I+S +G++Y   + NN  LG         P LV GL  + +VK+A +  G+H LAL     +++WG                 DVL   LV +L       ++I IA G ++SAAI+  GELYTWG+G YGRLGHG+ +DQ  P +V  L+G  V+ V+CGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   ++KV CGSQFS+ +T  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK++DVA GS HC+  TE GEVYSWG ND+ Q  D        P ++  L  K I  ++CG A + AW++ S
Sbjct:  411 EVISWG-----LLGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCG---------------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCS 756

HSP 7 Score: 138.658 bits (348), Expect = 3.171e-31
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L   + V I+ G     C+T  G++Y  G    GRLG G   D      + PK +EAL  Y ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  V  V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 4038 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSED-----QLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4294

HSP 8 Score: 125.176 bits (313), Expect = 3.298e-27
Identity = 92/303 (30.36%), Postives = 154/303 (50.83%), Query Frame = 2

Query: 9653 IIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVAC--GSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYK----VVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGA--QSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            + GP + EAL    + +VA     +  + L++NG+ ++    ++  LG         P+ ++    + +V +A      H  A+     L++WG GD            L   LV +L   +    V+ +ACGS    + A+T+D  +++WG G++G+LG G S    +P  +  +    V+ + CG+    + ++TENGQVW+WG GDY +LG G     + P  IE L+   IV +  G+   +A+T  GQVYSWG  D+ + G+GT  +   P +++ L   K+  VA GS+H +A T S
Sbjct:  426 VSGPIQCEALANLGVTQVACAE--KCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDV-----------LFCPLVSALSGKQTGKQVIHIACGS--TYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTES 703

HSP 9 Score: 124.02 bits (310), Expect = 8.856e-27
Identity = 92/265 (34.72%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +  + V+ I  G   S  +T  G+++TWGKG Y RLGHG  +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3930 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKS 4194

HSP 10 Score: 112.849 bits (281), Expect = 1.893e-23
Identity = 175/743 (23.55%), Postives = 299/743 (40.24%), Query Frame = 2

Query: 4529 LNLVALVKHV---NLCEELANH---IMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAY----------------------------------------------KAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQ--LVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTL-ITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKL 6556
            L L  L+KH    N+   L +H    + Q   + +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RWK I                                                K  + +K PK   D WQ + + V      K ++ N       V  +       G I +F+L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++   FC    +    E  N +E + D LK  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + N L  T        +LLL +G+L L QT+LR        LI   C+++ +     VM  S  +  E+ K  +   L +S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L         E P     +++ +D                     ++++  +E E++  + +        P+ L+L S   L+QA+ +         V+     S+       LL  L+   ++  +     S K +Y+EQ   WC   F+ ++ I        +   WI L +K  E     S+  ++  QIL +++L+ +
Sbjct: 1415 LLLCCLLKHEDLGNIALSLVHHGALSVEQVKHKTLPKSVVDVCRVVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIVSKLKL-----------LSSVP---RWKRIVQKIIREKRKKKVPKKSESADVDDTKLGNEEGEMEESCVVPSSPVSVDKKTVPIKSPK---DKWQPLLSTVAGVHKYKWLKHN-------VQGTYPQSALLGTIVEFVLKEEPVDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LAAKTFLLPSVQYAM---FCGWQRL--VPEGTNISEPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNTLMDASSCFKEMGIQPVPLQTITNENPSGPSLGTIPQARFMLVMVNML--TCQHGAKSLNLLLNSGMLALTQTILR--------LIGPSCENSEDDSSVCVMGASATVLEESRKETTPVQLPASGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKL--------TEPPP--ATQAMAED---------------------SDTEDDSEGEQIDKNLH--------PTSLMLMSTVNLLQALCLSA------GVNAEVMQSETTRTLCGLLRMLVESGTMDKT--STQSNKLVYKEQHKSWCTLGFIRSIAIMPQMCSTLSMPQWISLLMKIVEGPESFSAA-SLQRQILAVRLLQAV 2058

HSP 11 Score: 112.464 bits (280), Expect = 2.413e-23
Identity = 66/166 (39.76%), Postives = 90/166 (54.22%), Query Frame = 2

Query: 13214 GAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTR-----PTSCNLLENKSAVSL 13690
            G  VI + CGS +S  +TA GE+YTWG+G+Y RLGHGS      P  V  L   K++DV+CGS     +  TE+G+V+SWGD D G+LG G +     P++IE L    I +V CGS  ++A  T  G      +  +QRL   T      P   N L+ K  V +
Sbjct:  526 GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIA-ITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDV 690

HSP 12 Score: 108.612 bits (270), Expect = 3.602e-22
Identity = 87/265 (32.83%), Postives = 132/265 (49.81%), Query Frame = 2

Query: 12515 VLCEHLSALRPRQIIGGEQSLFI---------VSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            + C  +SAL  +Q   G+Q + I         ++ DG +Y  G GN GRLG GS+E    P+LV+GL+   VV V+  SG    L++  NG V++WGD +  KLG     + G D   TP L++ L   +I+ +  G   S AI++ G++Y+WGKG   RLGHG  +   +PKI+  L+G  V+ VA GS    T C+   E           V+SWG  D  +          +P  +  L+   ++ + CG   S   ++  E
Sbjct:  512 LFCPLVSALSGKQT--GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLG-----RGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGS----THCLALTESGE--------VYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCSE 757

HSP 13 Score: 97.4413 bits (241), Expect = 8.872e-19
Identity = 77/243 (31.69%), Postives = 114/243 (46.91%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++      +V  +A G  HS  +T +G++Y+ G+   G+LGHGD +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++       +++      S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4021 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEA--LQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTGVGVTKVE----CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4250

HSP 14 Score: 85.8853 bits (211), Expect = 2.761e-15
Identity = 48/142 (33.80%), Postives = 76/142 (53.52%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +V+DV      +  L+VTE GQV+SWG    GKLG+G +   K P +I+      L + +V CG + S+ +T+ G +YS G+    +LGHG   + H+      + L G  V  +AV     + L+  G +++WGS  D C+
Sbjct:  580 KVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHG--TEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSN-DQCQ 716

HSP 15 Score: 84.3445 bits (207), Expect = 7.730e-15
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3035 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGK 3208

HSP 16 Score: 81.2629 bits (199), Expect = 6.926e-14
Identity = 43/136 (31.62%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T AG++Y+WG    G+LG GD++D+ +P +++       +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L GV V ++      S+ L+  GA++TWG
Sbjct: 4072 VVDIAAG--GAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQ--GYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGVGVTKVECGSQFSVALTKSGAVYTWG 4201

HSP 17 Score: 80.4925 bits (197), Expect = 1.070e-13
Identity = 47/135 (34.81%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   + V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4123 RVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4253

HSP 18 Score: 76.6406 bits (187), Expect = 1.857e-12
Identity = 59/211 (27.96%), Postives = 99/211 (46.92%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 3012 IPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQAVCQIECGAQFSLALTKSGVVWTWG 3207

HSP 19 Score: 75.0998 bits (183), Expect = 4.218e-12
Identity = 52/197 (26.40%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3077 RIRDIACGSSHSAAITSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWG 3259

HSP 20 Score: 72.7886 bits (177), Expect = 2.121e-11
Identity = 52/169 (30.77%), Postives = 79/169 (46.75%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +YTW
Sbjct: 2937 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYTW 3100

HSP 21 Score: 70.0922 bits (170), Expect = 1.466e-10
Identity = 61/254 (24.02%), Postives = 117/254 (46.06%), Query Frame = 2

Query: 1424 IKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            + ++ C+     +LS  G LY           T  + +N +  Q        V  L S+N ++ + A+    H LA++   +++SWG             D     ++   S  +   QV  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D+ +P+ +T    + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ + K G VY+W K
Sbjct:  440 VTQVACAEKCFLILSRNGKLY-----------TQAYNNNTLGPQL-------VQGLASRN-IVKIAAHPDGQHYLALSATSELFSWGCG-----------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGK 659

HSP 22 Score: 63.929 bits (154), Expect = 1.207e-8
Identity = 45/124 (36.29%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G  V  IA  G  S C++  G ++TWG
Sbjct: 3976 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGTEVVDIAAGGAHSACITAAGELYTWG 4095

HSP 23 Score: 57.3806 bits (137), Expect = 9.764e-7
Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   V++     +++ V   + + H LAVT+AGQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3188 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLE--GQKITRVACGSSHSVAWT 3302

HSP 24 Score: 54.299 bits (129), Expect = 9.045e-6
Identity = 39/126 (30.95%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VY+ G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  +++ G ++TWG
Sbjct: 2978 SKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAAITSSGELYTWG 3101

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 1006.9 bits (2602), Expect = 0.000e+0
Identity = 599/1321 (45.34%), Postives = 806/1321 (61.01%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L IMD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L    ++++ ++           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP +F++E   +  +       L  +   + A  E  D   F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ +GELYTWGKGRYGRLGHG+ +DQ  PK+VEAL+GY VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL  +        S+  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+   +             PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A  T +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   I Y++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFW++ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3590 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTIMDGANRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EFGQSININRLLGDGETETRAMS-----------FSGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRQFLDEVAKKIRE-------LMADNENMNAGHESHD--TFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPANAGKLPSQ------VPMEYNHLQEIMIIALRNRLLLLHHISELFCPCIPMFDLEGRLDESGQGPSIGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKMASFS-------------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKTTLHMNMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMILPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAIGYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPTASLIQWFWDVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4780

HSP 2 Score: 482.256 bits (1240), Expect = 4.330e-135
Identity = 265/481 (55.09%), Postives = 327/481 (67.98%), Query Frame = 2

Query: 9263 CNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKS-------------RIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            C ++  + +   LN L  Q+ +  ED  T     S+N  E+ D +   S              I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA
Sbjct: 2871 CRSSGIDCKIHELN-LVGQIRAEDEDMATVPFLASDNDEEDDDKASTGSFVRKKTAGLESTATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDALGA 3325

HSP 3 Score: 379.022 bits (972), Expect = 6.940e-104
Identity = 198/393 (50.38%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV++L+ Y+V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V ++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LPSQ    + H++E+
Sbjct: 3932 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPANAGKLPSQVPMEYNHLQEI 4319

HSP 4 Score: 352.058 bits (902), Expect = 9.773e-96
Identity = 206/382 (53.93%), Postives = 265/382 (69.37%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+ +G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G  V +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P ++  L G+ I RVACGS+H++AWTTV
Sbjct: 2936 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTV 3303

HSP 5 Score: 259.61 bits (662), Expect = 8.460e-68
Identity = 153/373 (41.02%), Postives = 221/373 (59.25%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  EAL+ L    ++   K    ++R GK+Y    ++N                +GP+ ++ L    IVK+A H  G+H +AL+   E FSWG GD       S L            GK+V+ +ACGS++SAAI   G LYTWG G+YGRLGHG +  +  P LV  L+  KVV V+CGS DAQTL++T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +++++ CG+Q S A+T++GQV++WGKGD  RLGHGT++H+R P  +  L+  K+V +AVG+ HCLA+T+ G+VYSWG ND  Q  +        P+++  L    I  ++CG + S AW++
Sbjct:  409 LQEVISWGL-----LGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN---------------TLGPQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDVLFCPLVSALSGKQ-------TGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSS 754

HSP 6 Score: 249.595 bits (636), Expect = 1.062e-64
Identity = 167/386 (43.26%), Postives = 223/386 (57.77%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSL----VKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV SWG      LG    + +  P+ CE L+ L   Q+   E+   I+S +G++Y   + NN  LG         P LV GL  + +VK+A +  G+H LAL     +++WG                 DVL   LV +L       ++I IA G ++SAAI+  GELYTWG+G YGRLGHG+ +DQ  P +V  L+G  V+ V+CGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   ++KV CGSQFS+ +T  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK++DVA GS HC+  TE GEVYSWG ND+ Q  D        P ++  L  K I  ++CG A + AW++ S
Sbjct:  411 EVISWG-----LLGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCG---------------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCS 756

HSP 7 Score: 138.658 bits (348), Expect = 3.145e-31
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L   + V I+ G     C+T  G++Y  G    GRLG G   D      + PK +EAL  Y ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  V  V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 4037 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSED-----QLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4293

HSP 8 Score: 125.176 bits (313), Expect = 3.382e-27
Identity = 92/303 (30.36%), Postives = 154/303 (50.83%), Query Frame = 2

Query: 9653 IIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVAC--GSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYK----VVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGA--QSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            + GP + EAL    + +VA     +  + L++NG+ ++    ++  LG         P+ ++    + +V +A      H  A+     L++WG GD            L   LV +L   +    V+ +ACGS    + A+T+D  +++WG G++G+LG G S    +P  +  +    V+ + CG+    + ++TENGQVW+WG GDY +LG G     + P  IE L+   IV +  G+   +A+T  GQVYSWG  D+ + G+GT  +   P +++ L   K+  VA GS+H +A T S
Sbjct:  426 VSGPIQCEALANLGVTQVACAE--KCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDV-----------LFCPLVSALSGKQTGKQVIHIACGS--TYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTES 703

HSP 9 Score: 124.02 bits (310), Expect = 9.081e-27
Identity = 92/265 (34.72%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +  + V+ I  G   S  +T  G+++TWGKG Y RLGHG  +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3929 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKS 4193

HSP 10 Score: 112.849 bits (281), Expect = 1.893e-23
Identity = 175/743 (23.55%), Postives = 299/743 (40.24%), Query Frame = 2

Query: 4529 LNLVALVKHV---NLCEELANH---IMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAY----------------------------------------------KAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQ--LVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTL-ITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKL 6556
            L L  L+KH    N+   L +H    + Q   + +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RWK I                                                K  + +K PK   D WQ + + V      K ++ N       V  +       G I +F+L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++   FC    +    E  N +E + D LK  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + N L  T        +LLL +G+L L QT+LR        LI   C+++ +     VM  S  +  E+ K  +   L +S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L         E P     +++ +D                     ++++  +E E++  + +        P+ L+L S   L+QA+ +         V+     S+       LL  L+   ++  +     S K +Y+EQ   WC   F+ ++ I        +   WI L +K  E     S+  ++  QIL +++L+ +
Sbjct: 1415 LLLCCLLKHEDLGNIALSLVHHGALSVEQVKHKTLPKSVVDVCRVVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIVSKLKL-----------LSSVP---RWKRIVQKIIREKRKKKVPKKSESADVDDTKLGNEEGEMEESCVVPSSPVSVDKKTVPIKSPK---DKWQPLLSTVAGVHKYKWLKHN-------VQGTYPQSALLGTIVEFVLKEEPVDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LAAKTFLLPSVQYAM---FCGWQRL--VPEGTNISEPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNTLMDASSCFKEMGIQPVPLQTITNENPSGPSLGTIPQARFMLVMVNML--TCQHGAKSLNLLLNSGMLALTQTILR--------LIGPSCENSEDDSSVCVMGASATVLEESRKETTPVQLPASGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKL--------TEPPP--ATQAMAED---------------------SDTEDDSEGEQIDKNLH--------PTSLMLMSTVNLLQALCLSA------GVNAEVMQSETTRTLCGLLRMLVESGTMDKT--STQSNKLVYKEQHKSWCTLGFIRSIAIMPQMCSTLSMPQWISLLMKIVEGPESFSAA-SLQRQILAVRLLQAV 2058

HSP 11 Score: 112.464 bits (280), Expect = 2.495e-23
Identity = 66/166 (39.76%), Postives = 90/166 (54.22%), Query Frame = 2

Query: 13214 GAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTR-----PTSCNLLENKSAVSL 13690
            G  VI + CGS +S  +TA GE+YTWG+G+Y RLGHGS      P  V  L   K++DV+CGS     +  TE+G+V+SWGD D G+LG G +     P++IE L    I +V CGS  ++A  T  G      +  +QRL   T      P   N L+ K  V +
Sbjct:  526 GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIA-ITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDV 690

HSP 12 Score: 108.612 bits (270), Expect = 3.694e-22
Identity = 87/265 (32.83%), Postives = 132/265 (49.81%), Query Frame = 2

Query: 12515 VLCEHLSALRPRQIIGGEQSLFI---------VSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            + C  +SAL  +Q   G+Q + I         ++ DG +Y  G GN GRLG GS+E    P+LV+GL+   VV V+  SG    L++  NG V++WGD +  KLG     + G D   TP L++ L   +I+ +  G   S AI++ G++Y+WGKG   RLGHG  +   +PKI+  L+G  V+ VA GS    T C+   E           V+SWG  D  +          +P  +  L+   ++ + CG   S   ++  E
Sbjct:  512 LFCPLVSALSGKQT--GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLG-----RGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGS----THCLALTESGE--------VYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCSE 757

HSP 13 Score: 97.4413 bits (241), Expect = 8.508e-19
Identity = 77/243 (31.69%), Postives = 114/243 (46.91%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++      +V  +A G  HS  +T +G++Y+ G+   G+LGHGD +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++       +++      S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4020 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEA--LQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTGVGVTKVE----CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4249

HSP 14 Score: 85.8853 bits (211), Expect = 2.761e-15
Identity = 48/142 (33.80%), Postives = 76/142 (53.52%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +V+DV      +  L+VTE GQV+SWG    GKLG+G +   K P +I+      L + +V CG + S+ +T+ G +YS G+    +LGHG   + H+      + L G  V  +AV     + L+  G +++WGS  D C+
Sbjct:  580 KVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHG--TEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSN-DQCQ 716

HSP 15 Score: 84.3445 bits (207), Expect = 7.794e-15
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3034 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGK 3207

HSP 16 Score: 81.2629 bits (199), Expect = 6.868e-14
Identity = 43/136 (31.62%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T AG++Y+WG    G+LG GD++D+ +P +++       +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L GV V ++      S+ L+  GA++TWG
Sbjct: 4071 VVDIAAG--GAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQ--GYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGVGVTKVECGSQFSVALTKSGAVYTWG 4200

HSP 17 Score: 80.4925 bits (197), Expect = 1.061e-13
Identity = 47/135 (34.81%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   + V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4122 RVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4252

HSP 18 Score: 76.2554 bits (186), Expect = 1.889e-12
Identity = 59/211 (27.96%), Postives = 99/211 (46.92%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 3011 IPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQAVCQIECGAQFSLALTKSGVVWTWG 3206

HSP 19 Score: 75.0998 bits (183), Expect = 4.325e-12
Identity = 52/197 (26.40%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3076 RIRDIACGSSHSAAITSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWG 3258

HSP 20 Score: 72.7886 bits (177), Expect = 2.121e-11
Identity = 52/169 (30.77%), Postives = 79/169 (46.75%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +YTW
Sbjct: 2936 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTAEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYTW 3099

HSP 21 Score: 70.0922 bits (170), Expect = 1.454e-10
Identity = 61/254 (24.02%), Postives = 117/254 (46.06%), Query Frame = 2

Query: 1424 IKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            + ++ C+     +LS  G LY           T  + +N +  Q        V  L S+N ++ + A+    H LA++   +++SWG             D     ++   S  +   QV  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D+ +P+ +T    + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ + K G VY+W K
Sbjct:  440 VTQVACAEKCFLILSRNGKLY-----------TQAYNNNTLGPQL-------VQGLASRN-IVKIAAHPDGQHYLALSATSELFSWGCG-----------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGK 659

HSP 22 Score: 63.929 bits (154), Expect = 1.269e-8
Identity = 45/124 (36.29%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G  V  IA  G  S C++  G ++TWG
Sbjct: 3975 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGTEVVDIAAGGAHSACITAAGELYTWG 4094

HSP 23 Score: 57.3806 bits (137), Expect = 9.522e-7
Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   V++     +++ V   + + H LAVT+AGQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3187 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLE--GQKITRVACGSSHSVAWT 3301

HSP 24 Score: 54.299 bits (129), Expect = 9.121e-6
Identity = 39/126 (30.95%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VY+ G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  +++ G ++TWG
Sbjct: 2977 SKSLFAVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAAITSSGELYTWG 3100

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Xenopus
Match: HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:100487407])

HSP 1 Score: 944.11 bits (2439), Expect = 0.000e+0
Identity = 574/1321 (43.45%), Postives = 785/1321 (59.42%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T     V +       +++   C              N       +G+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L    ++++ ++           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP +F++E   +  +       L  +   + A  E  D   F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ +GELYTWGKGRYGRLGHG+ +DQ  PK+VEAL+GY VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL  +        S+  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+   +             PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A  T +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   I Y++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFW++ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3500 VVVESSHPYTDDTSTKYPVTVSLFLHYHMQYLNACI-------------NYVFSVYFTGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EFGQSININRLLGDGETETRAMS-----------FSGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRQFLDEVAKKIRE-------LMADNENMNAGHESHD--TFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPANAGKLPSQ------VPMEYNHLQEIMIIALRNRLLLLHHISELFCPCIPMFDLEGRLDESGQGPSIGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKMASFS-------------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKTTLHMNMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMILPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAIGYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPTASLIQWFWDVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4677

HSP 2 Score: 444.891 bits (1143), Expect = 9.662e-124
Identity = 253/481 (52.60%), Postives = 311/481 (64.66%), Query Frame = 2

Query: 9263 CNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKS-------------RIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            C ++  + +   LN L  Q+ +  ED  T     S+N  E+ D +   S              I +K++VWGLNDKDQLG    SK+     +     L            F VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA
Sbjct: 2792 CRSSGIDCKIHELN-LVGQIRAEDEDMATVPFLASDNDEEDDDKASTGSFVRKKTAGLESTATIRTKVFVWGLNDKDQLGGLKGSKLLFQYFSHCSFSLR-----------FTVTAEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDALGA 3235

HSP 3 Score: 379.022 bits (972), Expect = 8.030e-104
Identity = 198/393 (50.38%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV++L+ Y+V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V ++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LPSQ    + H++E+
Sbjct: 3829 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPANAGKLPSQVPMEYNHLQEI 4216

HSP 4 Score: 319.701 bits (818), Expect = 6.460e-86
Identity = 194/382 (50.79%), Postives = 253/382 (66.23%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSK+          +LR           F V+ +G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G  V +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P ++  L G+ I RVACGS+H++AWTTV
Sbjct: 2857 KVFVWGLNDKDQLGGLKGSKLLFQYFSHCSFSLR-----------FTVTAEGKVYACGEATNGRLGLGISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLEGQKITRVACGSSHSVAWTTV 3213

HSP 5 Score: 259.61 bits (662), Expect = 7.985e-68
Identity = 153/373 (41.02%), Postives = 221/373 (59.25%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  EAL+ L    ++   K    ++R GK+Y    ++N                +GP+ ++ L    IVK+A H  G+H +AL+   E FSWG GD       S L            GK+V+ +ACGS++SAAI   G LYTWG G+YGRLGHG +  +  P LV  L+  KVV V+CGS DAQTL++T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +++++ CG+Q S A+T++GQV++WGKGD  RLGHGT++H+R P  +  L+  K+V +AVG+ HCLA+T+ G+VYSWG ND  Q  +        P+++  L    I  ++CG + S AW++
Sbjct:  409 LQEVISWGL-----LGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN---------------TLGPQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDVLFCPLVSALSGKQ-------TGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSS 754

HSP 6 Score: 249.595 bits (636), Expect = 9.072e-65
Identity = 167/386 (43.26%), Postives = 223/386 (57.77%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSL----VKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV SWG      LG    + +  P+ CE L+ L   Q+   E+   I+S +G++Y   + NN  LG         P LV GL  + +VK+A +  G+H LAL     +++WG                 DVL   LV +L       ++I IA G ++SAAI+  GELYTWG+G YGRLGHG+ +DQ  P +V  L+G  V+ V+CGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   ++KV CGSQFS+ +T  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK++DVA GS HC+  TE GEVYSWG ND+ Q  D        P ++  L  K I  ++CG A + AW++ S
Sbjct:  411 EVISWG-----LLGWKYYANVSGPIQCEALANLGVTQVACAEKCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCG---------------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCS 756

HSP 7 Score: 138.658 bits (348), Expect = 3.057e-31
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L   + V I+ G     C+T  G++Y  G    GRLG G   D      + PK +EAL  Y ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  V  V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 3934 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSED-----QLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4190

HSP 8 Score: 125.561 bits (314), Expect = 3.101e-27
Identity = 92/303 (30.36%), Postives = 154/303 (50.83%), Query Frame = 2

Query: 9653 IIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVAC--GSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYK----VVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGA--QSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            + GP + EAL    + +VA     +  + L++NG+ ++    ++  LG         P+ ++    + +V +A      H  A+     L++WG GD            L   LV +L   +    V+ +ACGS    + A+T+D  +++WG G++G+LG G S    +P  +  +    V+ + CG+    + ++TENGQVW+WG GDY +LG G     + P  IE L+   IV +  G+   +A+T  GQVYSWG  D+ + G+GT  +   P +++ L   K+  VA GS+H +A T S
Sbjct:  426 VSGPIQCEALANLGVTQVACAE--KCFLILSRNGKLYTQAYNNN-TLG---------PQLVQGLASRNIVKIAAHPDGQHYLALSATSELFSWGCGDV-----------LFCPLVSALSGKQTGKQVIHIACGS--TYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTES 703

HSP 9 Score: 124.02 bits (310), Expect = 9.131e-27
Identity = 92/265 (34.72%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +  + V+ I  G   S  +T  G+++TWGKG Y RLGHG  +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3826 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGVGVTKVECGSQFSVALTKS 4090

HSP 10 Score: 112.464 bits (280), Expect = 2.347e-23
Identity = 66/166 (39.76%), Postives = 90/166 (54.22%), Query Frame = 2

Query: 13214 GAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTR-----PTSCNLLENKSAVSL 13690
            G  VI + CGS +S  +TA GE+YTWG+G+Y RLGHGS      P  V  L   K++DV+CGS     +  TE+G+V+SWGD D G+LG G +     P++IE L    I +V CGS  ++A  T  G      +  +QRL   T      P   N L+ K  V +
Sbjct:  526 GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIA-ITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDV 690

HSP 11 Score: 109.768 bits (273), Expect = 1.480e-22
Identity = 144/563 (25.58%), Postives = 230/563 (40.85%), Query Frame = 2

Query: 4529 LNLVALVKHV---NLCEELANH---IMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAY----------------------------------------------KAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQ--LVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKKS-------IEDVKNETPSE 5998
            L L  L+KH    N+   L +H    + Q   + +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RWK I                                                K  + +K PK   D WQ + + V      K ++ N       V  +       G I +F+L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++   FC    +    E  N +E + D LK  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + N L  T        +LLL +G+L L QT+LR        LI   C+++ +     VM  S  +  E+ K  +   L +S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L +         ED   E  SE
Sbjct: 1410 LLLCCLLKHEDLGNIALSLVHHGALSVEQVKHKTLPKSVVDVCRVVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIVSKLKL-----------LSSVP---RWKRIVQKIIREKRKKKVPKKSESADVDDTKLGNEEGEMEESCVVPSSPVSVDKKTVPIKSPK---DKWQPLLSTVAGVHKYKWLKHN-------VQGTYPQSALLGTIVEFVLKEEPVDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LAAKTFLLPSVQYAM---FCGWQRL--VPEGTNISEPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNTLMDASSCFKEMGIQPVPLQTITNENPSGPSLGTIPQARFMLVMVNML--TCQHGAKSLNLLLNSGMLALTQTILR--------LIGPSCENSEDDSSVCVMGASATVLEESRKETTPVQLPASGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLTEPPPATQAMAEDSDTEDDSE 1921

HSP 12 Score: 108.997 bits (271), Expect = 3.169e-22
Identity = 87/265 (32.83%), Postives = 132/265 (49.81%), Query Frame = 2

Query: 12515 VLCEHLSALRPRQIIGGEQSLFI---------VSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            + C  +SAL  +Q   G+Q + I         ++ DG +Y  G GN GRLG GS+E    P+LV+GL+   VV V+  SG    L++  NG V++WGD +  KLG     + G D   TP L++ L   +I+ +  G   S AI++ G++Y+WGKG   RLGHG  +   +PKI+  L+G  V+ VA GS    T C+   E           V+SWG  D  +          +P  +  L+   ++ + CG   S   ++  E
Sbjct:  512 LFCPLVSALSGKQT--GKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLG-----RGGSDGCKTPKLIEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHGTEEHVRYPKIMNGLQGKKVVDVAVGS----THCLALTESGE--------VYSWGSNDQCQHFDTLRIAKPVPSVLPGLDSKHIVGISCGPAQSFAWSSCSE 757

HSP 13 Score: 97.4413 bits (241), Expect = 8.279e-19
Identity = 77/243 (31.69%), Postives = 114/243 (46.91%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++      +V  +A G  HS  +T +G++Y+ G+   G+LGHGD +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++       +++      S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 3917 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GTEVVDIAAGGAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEA--LQGYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTGVGVTKVE----CGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4146

HSP 14 Score: 85.8853 bits (211), Expect = 2.371e-15
Identity = 48/142 (33.80%), Postives = 76/142 (53.52%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +V+DV      +  L+VTE GQV+SWG    GKLG+G +   K P +I+      L + +V CG + S+ +T+ G +YS G+    +LGHG   + H+      + L G  V  +AV     + L+  G +++WGS  D C+
Sbjct:  580 KVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDIVKVRCGSQFSIAITKDGQVYSWGKGDNQRLGHG--TEEHVRYPKIMNGLQGKKVVDVAVGSTHCLALTESGEVYSWGSN-DQCQ 716

HSP 15 Score: 84.7297 bits (208), Expect = 6.418e-15
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 2944 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQAVCQIECGAQFSLALTKSGVVWTWGK 3117

HSP 16 Score: 81.2629 bits (199), Expect = 6.098e-14
Identity = 43/136 (31.62%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T AG++Y+WG    G+LG GD++D+ +P +++       +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L GV V ++      S+ L+  GA++TWG
Sbjct: 3968 VVDIAAG--GAHSACITAAGELYTWGKGRYGRLGHGDSEDQLKPKLVEALQ--GYRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGVGVTKVECGSQFSVALTKSGAVYTWG 4097

HSP 17 Score: 80.8777 bits (198), Expect = 9.113e-14
Identity = 47/135 (34.81%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   + V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4019 RVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GVGVTKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4149

HSP 18 Score: 76.6406 bits (187), Expect = 1.734e-12
Identity = 59/211 (27.96%), Postives = 99/211 (46.92%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 2921 IPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQAVCQIECGAQFSLALTKSGVVWTWG 3116

HSP 19 Score: 75.485 bits (184), Expect = 3.592e-12
Identity = 52/197 (26.40%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 2986 RIRDIACGSSHSAAITSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQAVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDAGQVYAWG 3168

HSP 20 Score: 70.4774 bits (171), Expect = 1.270e-10
Identity = 61/254 (24.02%), Postives = 117/254 (46.06%), Query Frame = 2

Query: 1424 IKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            + ++ C+     +LS  G LY           T  + +N +  Q        V  L S+N ++ + A+    H LA++   +++SWG             D     ++   S  +   QV  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D+ +P+ +T    + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ + K G VY+W K
Sbjct:  440 VTQVACAEKCFLILSRNGKLY-----------TQAYNNNTLGPQL-------VQGLASRN-IVKIAAHPDGQHYLALSATSELFSWGCG-----------DVLFCPLVSALSGKQTGKQVIHIACGSTYSAAITADGELYTWGRGNYGRLGHGSSEDQTVPMLVTGLKGLKVVDVSCGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDIVKVRCGSQFSIAITKDGQVYSWGK 659

HSP 21 Score: 63.929 bits (154), Expect = 1.146e-8
Identity = 45/124 (36.29%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G  V  IA  G  S C++  G ++TWG
Sbjct: 3872 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGTEVVDIAAGGAHSACITAAGELYTWG 3991

HSP 22 Score: 60.077 bits (144), Expect = 1.547e-7
Identity = 47/169 (27.81%), Postives = 74/169 (43.79%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ WG N   +LG    K  K   +   FS C   ++           +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +YTW
Sbjct: 2857 KVFVWGLNDKDQLG--GLKGSK--LLFQYFSHCSFSLR---------FTVTAEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSNYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYTW 3009

HSP 23 Score: 57.3806 bits (137), Expect = 9.432e-7
Identity = 35/123 (28.46%), Postives = 60/123 (48.78%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   V++     +++ V   + + H LAVT+AGQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3097 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDAGQVYAWGDNDHGQQGNGTTTVNRKPTLVHGLE--GQKITRVACGSSHSVAWT 3211

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 998.038 bits (2579), Expect = 0.000e+0
Identity = 596/1325 (44.98%), Postives = 801/1325 (60.45%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +S+ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++L+P      +   F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    ++ WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3614 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------VLSCPSMDLVTCLLDFRLNLTSNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRRLLTT-------EFGQSININRLLGENDGESRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSESMDVLHESHSIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLNPATRAPVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4804

HSP 2 Score: 480.33 bits (1235), Expect = 1.359e-134
Identity = 250/418 (59.81%), Postives = 306/418 (73.21%), Query Frame = 2

Query: 9413 IMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    +++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA
Sbjct: 2958 IRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG----MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGA 3350

HSP 3 Score: 374.4 bits (960), Expect = 1.493e-102
Identity = 195/393 (49.62%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 3956 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 4343

HSP 4 Score: 356.295 bits (913), Expect = 3.790e-97
Identity = 206/382 (53.93%), Postives = 268/382 (70.16%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VY+ G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3328

HSP 5 Score: 285.419 bits (729), Expect = 1.138e-75
Identity = 161/377 (42.71%), Postives = 227/377 (60.21%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L  + ++   K    ++R G+VY    +S+               ++ P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +VI++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        PT +  L    I  +ACG + S AW++
Sbjct:  423 LQEVIGWGL-----IGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD---------------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSS 779

HSP 6 Score: 264.618 bits (675), Expect = 2.271e-69
Identity = 170/384 (44.27%), Postives = 223/384 (58.07%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L++L   Q+   E+   I+S +GRVY   + ++          +  P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   VIKV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  418 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD----------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCS 781

HSP 7 Score: 136.346 bits (342), Expect = 1.112e-30
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 4061 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 4317

HSP 8 Score: 117.857 bits (294), Expect = 4.522e-25
Identity = 90/265 (33.96%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3953 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4217

HSP 9 Score: 102.834 bits (255), Expect = 1.395e-20
Identity = 65/209 (31.10%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D I+V   S +S+ L K G VY+W K
Sbjct:  481 DMLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGK 684

HSP 10 Score: 98.2117 bits (243), Expect = 3.711e-19
Identity = 143/519 (27.55%), Postives = 214/519 (41.23%), Query Frame = 2

Query: 4667 IIKRHQQTCISYKELCSNINIRCRFLIDEVE--------ILS-------------INNSAINAGRKKSI-----------NINDFTSDH-----LTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCD-KVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWC---QDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL-------KKSIEDVKNETPSEC--GVRSLMKDISML 6037
            +IK HQ+   SYKE+C+ +  R RFL +E+         I+S             I    I   RKK +            I +  SD      L  +P     + I+      +K PK   D WQ + N V      K ++QN       V            I +F L +E +D++K+R  +L +    +++ + +  ILK     L     LLP VQ ++   FC  +  I +  + G   E + D L+  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + + L  T+    +   LLL +G L L QT LR        LI   C   +D  N       S  +  ET K  +   L  S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L       + S ED   E  SE   G R++     ML
Sbjct: 1492 LIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCSDLSIMSKFKLLGSLPRWRRIAQKIIRERRKKRVPKKPESIDSEEKIGNEESDLEEACVLPHSPINVDKRPIS------MKSPK---DKWQPLLNTVTGVHKYKWLKQN-------VQGLYPQSALLNTIVEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILK-----LAAKSFLLPSVQYAM---FCGWQRLIPEGIDIG---EPLTDCLRDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRSVLMDASARFKELGIQPVPLQTITNENPAGPSLGTIPQARFLLVMLSML--TLQHGANNLDLLLNSGTLALTQTALR--------LIGPTCDSVEDDMNAS-ARGASATVLEETRKETAPVQLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLVELPVSSQPSAEDSDTEDDSEAEQGERNIHPTAMML 1965

HSP 11 Score: 96.6709 bits (239), Expect = 1.178e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4044 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4273

HSP 12 Score: 84.7297 bits (208), Expect = 4.871e-15
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3059 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3232

HSP 13 Score: 83.9593 bits (206), Expect = 7.341e-15
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  605 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 741

HSP 14 Score: 82.8037 bits (203), Expect = 1.585e-14
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  626 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGL 759

HSP 15 Score: 82.0333 bits (201), Expect = 3.176e-14
Identity = 60/205 (29.27%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  V+K  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  572 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACG 770

HSP 16 Score: 81.2629 bits (199), Expect = 5.517e-14
Identity = 48/136 (35.29%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4145 HRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4276

HSP 17 Score: 76.2554 bits (186), Expect = 1.480e-12
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3101 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3283

HSP 18 Score: 75.8702 bits (185), Expect = 2.424e-12
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct: 3036 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3282

HSP 19 Score: 73.1738 bits (178), Expect = 1.382e-11
Identity = 67/235 (28.51%), Postives = 104/235 (44.26%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVS----------------MISKGDGEFYFLDKSG 2293
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +YSCG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+                + S GDG+F  L + G
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG-MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3190

HSP 20 Score: 63.1586 bits (152), Expect = 1.436e-8
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 3999 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 4118

HSP 21 Score: 56.9954 bits (136), Expect = 9.508e-7
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3212 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3326

HSP 22 Score: 54.6842 bits (130), Expect = 4.821e-6
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VYS G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  L++ G ++TWG
Sbjct: 3002 SKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAALTSSGELYTWG 3125

[Close]

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +S+ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++L+P      +   F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    ++ WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3614 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------VLSCPSMDLVTCLLDFRLNLTSNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRRLLTT-------EFGQSININRLLGENDGESRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSESMDVLHESHSIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLNPATRAPVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4804

HSP 2 Score: 480.33 bits (1235), Expect = 1.359e-134
Identity = 250/418 (59.81%), Postives = 306/418 (73.21%), Query Frame = 2

Query: 9413 IMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    +++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA
Sbjct: 2958 IRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG----MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGA 3350

HSP 3 Score: 374.4 bits (960), Expect = 1.493e-102
Identity = 195/393 (49.62%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 3956 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 4343

HSP 4 Score: 356.295 bits (913), Expect = 3.790e-97
Identity = 206/382 (53.93%), Postives = 268/382 (70.16%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VY+ G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3328

HSP 5 Score: 285.419 bits (729), Expect = 1.138e-75
Identity = 161/377 (42.71%), Postives = 227/377 (60.21%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L  + ++   K    ++R G+VY    +S+               ++ P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +VI++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        PT +  L    I  +ACG + S AW++
Sbjct:  423 LQEVIGWGL-----IGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD---------------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSS 779

HSP 6 Score: 264.618 bits (675), Expect = 2.271e-69
Identity = 170/384 (44.27%), Postives = 223/384 (58.07%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L++L   Q+   E+   I+S +GRVY   + ++          +  P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   VIKV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  418 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD----------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCS 781

HSP 7 Score: 136.346 bits (342), Expect = 1.112e-30
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 4061 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 4317

HSP 8 Score: 117.857 bits (294), Expect = 4.522e-25
Identity = 90/265 (33.96%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3953 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4217

HSP 9 Score: 102.834 bits (255), Expect = 1.395e-20
Identity = 65/209 (31.10%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D I+V   S +S+ L K G VY+W K
Sbjct:  481 DMLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGK 684

HSP 10 Score: 98.2117 bits (243), Expect = 3.711e-19
Identity = 143/519 (27.55%), Postives = 214/519 (41.23%), Query Frame = 2

Query: 4667 IIKRHQQTCISYKELCSNINIRCRFLIDEVE--------ILS-------------INNSAINAGRKKSI-----------NINDFTSDH-----LTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCD-KVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWC---QDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL-------KKSIEDVKNETPSEC--GVRSLMKDISML 6037
            +IK HQ+   SYKE+C+ +  R RFL +E+         I+S             I    I   RKK +            I +  SD      L  +P     + I+      +K PK   D WQ + N V      K ++QN       V            I +F L +E +D++K+R  +L +    +++ + +  ILK     L     LLP VQ ++   FC  +  I +  + G   E + D L+  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + + L  T+    +   LLL +G L L QT LR        LI   C   +D  N       S  +  ET K  +   L  S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L       + S ED   E  SE   G R++     ML
Sbjct: 1492 LIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCSDLSIMSKFKLLGSLPRWRRIAQKIIRERRKKRVPKKPESIDSEEKIGNEESDLEEACVLPHSPINVDKRPIS------MKSPK---DKWQPLLNTVTGVHKYKWLKQN-------VQGLYPQSALLNTIVEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILK-----LAAKSFLLPSVQYAM---FCGWQRLIPEGIDIG---EPLTDCLRDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRSVLMDASARFKELGIQPVPLQTITNENPAGPSLGTIPQARFLLVMLSML--TLQHGANNLDLLLNSGTLALTQTALR--------LIGPTCDSVEDDMNAS-ARGASATVLEETRKETAPVQLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLVELPVSSQPSAEDSDTEDDSEAEQGERNIHPTAMML 1965

HSP 11 Score: 96.6709 bits (239), Expect = 1.178e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4044 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4273

HSP 12 Score: 84.7297 bits (208), Expect = 4.871e-15
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3059 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3232

HSP 13 Score: 83.9593 bits (206), Expect = 7.341e-15
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  605 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 741

HSP 14 Score: 82.8037 bits (203), Expect = 1.585e-14
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  626 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGL 759

HSP 15 Score: 82.0333 bits (201), Expect = 3.176e-14
Identity = 60/205 (29.27%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  V+K  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  572 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACG 770

HSP 16 Score: 81.2629 bits (199), Expect = 5.517e-14
Identity = 48/136 (35.29%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4145 HRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4276

HSP 17 Score: 76.2554 bits (186), Expect = 1.480e-12
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3101 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3283

HSP 18 Score: 75.8702 bits (185), Expect = 2.424e-12
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct: 3036 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3282

HSP 19 Score: 73.1738 bits (178), Expect = 1.382e-11
Identity = 67/235 (28.51%), Postives = 104/235 (44.26%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVS----------------MISKGDGEFYFLDKSG 2293
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +YSCG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+                + S GDG+F  L + G
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG-MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3190

HSP 20 Score: 63.1586 bits (152), Expect = 1.436e-8
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 3999 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 4118

HSP 21 Score: 56.9954 bits (136), Expect = 9.508e-7
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3212 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3326

HSP 22 Score: 54.6842 bits (130), Expect = 4.821e-6
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VYS G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  L++ G ++TWG
Sbjct: 3002 SKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAALTSSGELYTWG 3125

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 940.258 bits (2429), Expect = 0.000e+0
Identity = 574/1325 (43.32%), Postives = 777/1325 (58.64%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYA-DKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP                                    G+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +S+ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++L+P      +   F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    ++ WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3614 VVVESSHPYTDDTSTSGTVKIP------------------------------------GREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------VLSCPSMDLVTCLLDFRLNLTSNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRRLLTT-------EFGQSININRLLGENDGESRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSESMDVLHESHSIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLNPATRAPVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4768

HSP 2 Score: 479.945 bits (1234), Expect = 1.597e-134
Identity = 250/418 (59.81%), Postives = 306/418 (73.21%), Query Frame = 2

Query: 9413 IMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    +++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA
Sbjct: 2958 IRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG----MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGA 3350

HSP 3 Score: 374.015 bits (959), Expect = 1.686e-102
Identity = 195/393 (49.62%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 3920 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 4307

HSP 4 Score: 356.295 bits (913), Expect = 4.280e-97
Identity = 206/382 (53.93%), Postives = 268/382 (70.16%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VY+ G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3328

HSP 5 Score: 285.034 bits (728), Expect = 1.275e-75
Identity = 161/377 (42.71%), Postives = 227/377 (60.21%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L  + ++   K    ++R G+VY    +S+               ++ P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +VI++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        PT +  L    I  +ACG + S AW++
Sbjct:  423 LQEVIGWGL-----IGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD---------------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSS 779

HSP 6 Score: 264.233 bits (674), Expect = 2.678e-69
Identity = 170/384 (44.27%), Postives = 223/384 (58.07%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L++L   Q+   E+   I+S +GRVY   + ++          +  P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   VIKV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  418 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD----------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCS 781

HSP 7 Score: 136.346 bits (342), Expect = 1.168e-30
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 4025 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 4281

HSP 8 Score: 117.857 bits (294), Expect = 4.830e-25
Identity = 90/265 (33.96%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3917 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4181

HSP 9 Score: 103.219 bits (256), Expect = 1.304e-20
Identity = 65/209 (31.10%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D I+V   S +S+ L K G VY+W K
Sbjct:  481 DMLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGK 684

HSP 10 Score: 98.2117 bits (243), Expect = 3.708e-19
Identity = 143/519 (27.55%), Postives = 214/519 (41.23%), Query Frame = 2

Query: 4667 IIKRHQQTCISYKELCSNINIRCRFLIDEVE--------ILS-------------INNSAINAGRKKSI-----------NINDFTSDH-----LTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCD-KVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWC---QDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL-------KKSIEDVKNETPSEC--GVRSLMKDISML 6037
            +IK HQ+   SYKE+C+ +  R RFL +E+         I+S             I    I   RKK +            I +  SD      L  +P     + I+      +K PK   D WQ + N V      K ++QN       V            I +F L +E +D++K+R  +L +    +++ + +  ILK     L     LLP VQ ++   FC  +  I +  + G   E + D L+  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + + L  T+    +   LLL +G L L QT LR        LI   C   +D  N       S  +  ET K  +   L  S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L       + S ED   E  SE   G R++     ML
Sbjct: 1492 LIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCSDLSIMSKFKLLGSLPRWRRIAQKIIRERRKKRVPKKPESIDSEEKIGNEESDLEEACVLPHSPINVDKRPIS------MKSPK---DKWQPLLNTVTGVHKYKWLKQN-------VQGLYPQSALLNTIVEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILK-----LAAKSFLLPSVQYAM---FCGWQRLIPEGIDIG---EPLTDCLRDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRSVLMDASARFKELGIQPVPLQTITNENPAGPSLGTIPQARFLLVMLSML--TLQHGANNLDLLLNSGTLALTQTALR--------LIGPTCDSVEDDMNAS-ARGASATVLEETRKETAPVQLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLVELPVSSQPSAEDSDTEDDSEAEQGERNIHPTAMML 1965

HSP 11 Score: 96.6709 bits (239), Expect = 1.056e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4008 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4237

HSP 12 Score: 84.7297 bits (208), Expect = 4.515e-15
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3059 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3232

HSP 13 Score: 83.9593 bits (206), Expect = 6.861e-15
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  605 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 741

HSP 14 Score: 82.8037 bits (203), Expect = 1.625e-14
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  626 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGL 759

HSP 15 Score: 82.0333 bits (201), Expect = 3.200e-14
Identity = 60/205 (29.27%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  V+K  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  572 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACG 770

HSP 16 Score: 81.2629 bits (199), Expect = 5.200e-14
Identity = 48/136 (35.29%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4109 HRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4240

HSP 17 Score: 76.2554 bits (186), Expect = 1.442e-12
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3101 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3283

HSP 18 Score: 75.8702 bits (185), Expect = 2.228e-12
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct: 3036 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3282

HSP 19 Score: 73.1738 bits (178), Expect = 1.249e-11
Identity = 67/235 (28.51%), Postives = 104/235 (44.26%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVS----------------MISKGDGEFYFLDKSG 2293
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +YSCG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+                + S GDG+F  L + G
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG-MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3190

HSP 20 Score: 63.1586 bits (152), Expect = 1.412e-8
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 3963 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 4082

HSP 21 Score: 57.3806 bits (137), Expect = 8.963e-7
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3212 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3326

HSP 22 Score: 54.6842 bits (130), Expect = 4.700e-6
Identity = 41/126 (32.54%), Postives = 59/126 (46.83%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VYS G  T+G+LG G  +     P  I   S   ++   V  G  H+  LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  L++ G ++TWG
Sbjct: 3002 SKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAALTSSGELYTWG 3125

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Mouse
Match: Herc1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:MGI Symbol;Acc:MGI:2384589])

HSP 1 Score: 441.81 bits (1135), Expect = 6.260e-123
Identity = 341/1101 (30.97%), Postives = 539/1101 (48.96%), Query Frame = 2

Query: 11966 INDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSI---------------SPVS-TADEWAWFRNYCLTYRTTESLITNSSLPYRF-INEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWK---KCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSL-STRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL--NRQS------------VMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYAD-KTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET----ELENLQIP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            +N    +  FL  L  ++ +Q+ +E+P V    QL +S +++ L  L+  + LD +                P S   +EWAW   +  T +  E+L   +  P  F + +       EP  +D L   +          D  ++    D QI+ W  SRP+ W    KC         +V+ WG    GQL    G  + VP      S  + +Q+I G+   F++  +G V A G G+ GRLG G+++ +    ++S L+  +V ++  + G   H +AL  +G V++WGD +  KLG        +    P  +++L   E++ ++ G  HSA ++  G+L+T+G G YGRLG GN  ++  P+ V AL GY +  VACG     TL ++ +          + VW++GDGDYGKLG G       P K++ L G G+ KV CG+QFS+ LT  G VYT+G+     L  G   +  +P+++  L    I DVA G+ H +     G+VY+WG N EGQLG G T     P ++  L GK I +++ G  H+ AWT           S   +L L    P     L   S  ++  R  LL+H+++L  S+   ++L  N Q+            V  ++R +L P          +  TM   K +GP+I V R+                                G  C         K +F Q+  ++++    ++ S            LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I SP        ++D F+ +P A    +   F FLG L+G+AIRT +PL L ++ L+WK L    L   DL+  D   + +L S+  I+++    E  +  IP   +   + DGK V + I    +I +  SNR  Y++  I Y++HE D+    +R G+S ++P+PLL+L ++++LE +VCG   I +  LK +  YR V     ++ W W  +EE +NE R LF+RFV GR+RLP   +D+  +  +++V   Y    D LP + TCFF L+LP YSS+ ++ E+L YAI+ C+SID+D+Y
Sbjct: 3842 LNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQNCLPDPTSWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDL------EPVPEDELVLLM----------DNSKWINGMDEQIMSWATSRPEDWHLGGKC---------DVYLWGAGRHGQLAEA-GRNVMVPATAPSFS--QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHG----NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLN--HTLAVSAD---------GSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDAVPPQYGALREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRIST-----------------------------RGRKC---------KPIFVQIARQVVK----LNASD---------LRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPI-IPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVDVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY----DSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNY 4843

HSP 2 Score: 233.032 bits (593), Expect = 7.189e-60
Identity = 146/380 (38.42%), Postives = 211/380 (55.53%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFT-VWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLP 10558
            +Y+WG     QL  EA   V +P    + S+   V    G    F +   G V   G+ S GRLG G+  D+    +I      AL  + + ++    G   H++ALT++GE FSWG+GD GKLGH +  +   PR+I+  +G+ VV ++CG  HSA +   G L+T+G GDYGRLG G+T+ +  PE V +L  Y++ QVACG     TLA+++D + VW++GDGD+GKLG G S+    PQK++ +    + ++ CG Q S ALT++G V+T+G+     L  G  ++   P QI  L    I  +AVGA H LA+   G VY+WG N  GQ G G   +   PTLV+ L    I  ++ G  HS AWTA  +    P
Sbjct: 3997 VYLWGAGRHGQLA-EAGRNVMVPATAPSFSQAQQVIC--GQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVI-----SALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLN--HTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAP 4366

HSP 3 Score: 225.328 bits (573), Expect = 1.465e-57
Identity = 153/379 (40.37%), Postives = 210/379 (55.41%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIK-YFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            ++YVWG N   QL      K+  P L  + S  D  +I  G    F ++  G V   G  S GRLG+G   + +       K+L       I KV+   G   H +A T  GE FSWG+GD GKLGH +     YP+ I+   +GK VV V+ G  HSAA+   G LYTWG GD+GRLGHGD+  R  P LVK + +  V +V+CGS  + T+AL+ D  TVWS+G GD GKLG G ++    P+ IE +    + ++  G+QSS ALT  GQV+ WG G     G      +R P  IE+L  T+IV +++G  HCL+++   +VY+WG+N  GQ G G  T  + +P  VS L    I  ++ G+SHS+AWTA   D
Sbjct:  373 EVYVWGSNSSHQLVEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTL-----KKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGEVSCGS--SHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRD 739

HSP 4 Score: 182.185 bits (461), Expect = 1.775e-44
Identity = 139/386 (36.01%), Postives = 218/386 (56.48%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKV--PVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXX-XXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV+ WG N   QL  VEG++ K+  P L    S    + I  G+   F++S DG V A G G+ GRLG+G + +  T   ++    + + KV+ + G   H LA    G V++WGD +  KLG             P L++  ++ +++  ++AG  HSAA++  GELYTWG+G +GRLGHG+ + +  P +V+ +   +V  V+CGS  + T+ ++K  D R       +VWS+G GD GKLG G  +    P  IE L+G  + KV  GSQ SL LT++G+VY WG G     G  S+    +P+ + +L   +I+D++ G  HC+  + D EVY+WG+N  GQ G G +T   ++P+ +  L G  I +++ G++H+LAWT +
Sbjct:  373 EVYVWGSNSSHQL--VEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHG----NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGS--SHTIALSK--DGR-------TVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCG-SSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTAL 736

HSP 5 Score: 100.908 bits (250), Expect = 5.888e-20
Identity = 83/267 (31.09%), Postives = 132/267 (49.44%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGE-TFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALT 10219
            +++ WG  D  +LG   + + + P   EAL   + V +S G K    VT  GK++  G+   GRLG+G+ ++        P+R+ AL+ Y I +VA   G  H +A++ +G   +++G+GD GKLG  +    + P+K+    G  +  VACG+  S A+   GH+YT+G      L  G       P+ +  L    +  VA G+    TLAL S   V++WG    G+LG G ++    P  +  +   N+ QI  G   S A T
Sbjct: 4100 EVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKL-----PERVTALEGYQIGQVAC--GLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAE--HTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWT 4357

HSP 6 Score: 98.9821 bits (245), Expect = 2.484e-19
Identity = 95/358 (26.54%), Postives = 157/358 (43.85%), Query Frame = 2

Query: 12398 DAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEG---SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSG-LEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHG-SDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT---EDGEVYSW 13447
            +A + C  + S  G  V + G    G+LG  +    S +K      H S  +     G +      + +G V++ G G+ G+LG G++ + + P L+ G L+ K+VV   V++G +H  A+  +G +Y WG+ +  +LG             PTLVK +               A       ++++G G  G+LGHG+ +    PK++EAL+G  +  V  GS             S + L     V++WG G     G       + P  IE L    ++ +  G    L L+   EVY WG     + G G S   + KP+KV+ L+   I  ++ G+ H +  T    D +V +W
Sbjct:  409 EAGQYCTFVISTDG-SVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVV--CVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG----DSNSRNIPTLVKDISNV-GEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGS------------QSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAW 745

HSP 7 Score: 87.4261 bits (215), Expect = 6.649e-16
Identity = 57/193 (29.53%), Postives = 92/193 (47.67%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG-DIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTW--GSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW----LKYCTECNKSDDI 2197
            H  AVTE G++Y+WG    G+LG GD+  R  PT++   S     V +V+CG  H++ L++ G  ++S G    G+LGHGD    + P  I A  L G+ ++++      S+ L++ G ++ W  G+         +   PK+   +   R  I  I + DS    L     VY W    +  C + N +  I
Sbjct:  522 HSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS----NVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEA--LQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATR--IVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPI 706

HSP 8 Score: 86.2705 bits (212), Expect = 1.448e-15
Identity = 42/120 (35.00%), Postives = 74/120 (61.67%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAI 1996
             H +A+TE+G+V+SWG    GKLG G++  ++RP  I+       +V Q++CG +HS ++T  G +++ G    G+LG G+  ++ LP R+TA  L G  + Q+A   + ++ +S DG++
Sbjct: 4090 GHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQ--GEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTA--LEGYQIGQVACGLNHTLAVSADGSM 4205

HSP 9 Score: 80.8777 bits (198), Expect = 7.154e-14
Identity = 59/202 (29.21%), Postives = 96/202 (47.52%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC---GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG-AIFTWGSTFDNCRRHLSN---WSPK-IETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSD--DIQPEL 2209
             H LA T  G+V+SWG    GKLG G++  +K P +I    +  LQ K V C   G  HS  +T+ G++Y+ G    G+LGHGD   R++P  +     +G    +++     ++ LS DG  ++++G   +    H      + PK IE     +   I ++     +   L  +G VY W    C  C  S+   ++P+L
Sbjct:  468 GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLI----QGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVG----EVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMF---IRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKL 658

HSP 10 Score: 67.3958 bits (163), Expect = 8.706e-10
Identity = 39/117 (33.33%), Postives = 61/117 (52.14%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV----DGHQSMCLSNDGAIFTWG 2008
            VY WG    G+L +   ++   P    +FS    Q +QV CG+  + ++  +G + +CG    G+LG G+  D H+   I+A  L G +V Q+      DGH SM L+  G +F+WG
Sbjct: 3997 VYLWGAGRHGQLAEAG-RNVMVPATAPSFS----QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISA--LQGFVVTQLVTSCGSDGH-SMALTESGEVFSWG 4105

HSP 11 Score: 66.2402 bits (160), Expect = 1.590e-9
Identity = 45/132 (34.09%), Postives = 71/132 (53.79%), Query Frame = 2

Query: 1664 GQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEE-HSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPK 2056
            G V + G  + G+LGQG++ D    T+I       +     +CG + HS+ LT+SG+++S G    G+LGHG+   +  P +I A  L G  V Q++     S  +++DG +FT+G+  D  R  L N S K
Sbjct: 4044 GTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEA--LQGEEVVQMSCGFKHSAVVTSDGKLFTFGNG-DYGRLGLGNTSNK 4172

HSP 12 Score: 58.5362 bits (140), Expect = 3.884e-7
Identity = 61/264 (23.11%), Postives = 110/264 (41.67%), Query Frame = 2

Query: 1625 NIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG------------STFDNCRRHLSNWSPKIETCVNE-YRNEIDQIQVHDSTYSVLLKSGSVYTWLKY-CTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIKRNY 2368
            +I +     V+E  +VY WG+N+S +L +G  +   +P +  +FS      + +  G+  + +++  G + +CG+   G+LG GD  ++    ++T      I  +      DGH ++  + +G +F+WG            ST    +        K+  CV+  YR+            + + + G +YTW +         D     + T++K  + NV  +S G      L K G  RT  S    D+   G G   R Y
Sbjct:  359 SIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFS----DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGH-TLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHS-----------AAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVK-DISNVGEVSCGSSHTIALSKDG--RTVWSFGGGDNGKLGHGDTNRVY 603

HSP 13 Score: 57.7658 bits (138), Expect = 6.920e-7
Identity = 34/103 (33.01%), Postives = 55/103 (53.40%), Query Frame = 2

Query: 1646 LAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV 1954
            +A+T+ G VY++G +    L +G  ++  RP  I   +   + ++ VA G EH+L L  +GD+Y+ G N  GQLG G       P  +T   L G  ++QI+ 
Sbjct: 4250 VALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLA--GVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTV--LQGKNIRQISA 4348

HSP 14 Score: 56.225 bits (134), Expect = 1.611e-6
Identity = 46/159 (28.93%), Postives = 72/159 (45.28%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSM---CLSNDGAIFTW---------GSTFDNCRRHLSNWSPKIET 2065
            S   LA+T  GQVY+WG      LG G ++    RP +I+  +    ++  ++ G+ H L L+   ++Y+ G N MGQ G G+      PI      S L G+ ++QI+     S+    L  D  +  W          STF + R  L  +  KI +
Sbjct:  623 SQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAAT--RIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTG---PITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINS 774

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Mouse
Match: Herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:MGI Symbol;Acc:MGI:103234])

HSP 1 Score: 285.419 bits (729), Expect = 1.131e-78
Identity = 161/377 (42.71%), Postives = 227/377 (60.21%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L  + ++   K    ++R G+VY    +S+               ++ P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +VI++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        PT +  L    I  +ACG + S AW++
Sbjct:  423 LQEVIGWGL-----IGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD---------------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSS 779

HSP 2 Score: 260.766 bits (665), Expect = 1.583e-70
Identity = 170/384 (44.27%), Postives = 223/384 (58.07%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L++L   Q+   E+   I+S +GRVY   + ++          +  P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   VIKV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  418 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD----------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCS 781

HSP 3 Score: 102.449 bits (254), Expect = 1.047e-20
Identity = 65/209 (31.10%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D I+V   S +S+ L K G VY+W K
Sbjct:  481 DMLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGK 684

HSP 4 Score: 83.1889 bits (204), Expect = 9.408e-15
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  605 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 741

HSP 5 Score: 81.2629 bits (199), Expect = 3.021e-14
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  626 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGL 759

HSP 6 Score: 80.1073 bits (196), Expect = 8.542e-14
Identity = 60/205 (29.27%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  V+K  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  572 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACG 770

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. UniProt/SwissProt
Match: sp|O95714|HERC2_HUMAN (E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2)

HSP 1 Score: 1001.12 bits (2587), Expect = 0.000e+0
Identity = 597/1325 (45.06%), Postives = 804/1325 (60.68%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+       ++  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +++ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ V+ +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+       S  G      PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++LSP A    ++  F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3612 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKELLSDRC---------VLSCPSMDLVTCLLDFRLNLASNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRKLLTT-------EFGQSININRLLGENDGETRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSENMDVLHESHDIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHLSELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-------SSFG------PDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLSPAARAPVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4802

HSP 2 Score: 486.878 bits (1252), Expect = 8.744e-136
Identity = 270/519 (52.02%), Postives = 344/519 (66.28%), Query Frame = 2

Query: 9323 NSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDV-FDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLV 10876
            N   ED   NS +L        +++   + I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    I++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA  +    D +     N+    + SK        N  +L+ ++  L G   +   +  +   LQ++ AR+ V
Sbjct: 2930 NEEEEDEKGNSGSLIRKKAAGLESA---ATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG----ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGASYLGVPSDADSSAASNKISGASNSK-------PNRPSLAKILLSLDGNLAKQQALSHILTALQIMYARDAV 3413

HSP 3 Score: 374.4 bits (960), Expect = 8.398e-102
Identity = 196/393 (49.87%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++VV +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 3954 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 4341

HSP 4 Score: 358.992 bits (920), Expect = 4.022e-97
Identity = 211/396 (53.28%), Postives = 276/396 (69.70%), Query Frame = 2

Query: 12407 KKCWPIDSASGL--EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            KK   ++SA+ +  +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VYA G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2946 KKAAGLESAATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3327

HSP 5 Score: 281.952 bits (720), Expect = 9.415e-74
Identity = 160/377 (42.44%), Postives = 224/377 (59.42%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L    I+   K    ++R G+VY    +S+                + P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +V+++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        P  +  L    I  +ACG + S AW++
Sbjct:  422 LQEVIGWGL-----IGWKYYANVIGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNSD---------------TLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSS 778

HSP 6 Score: 262.307 bits (669), Expect = 6.763e-68
Identity = 170/384 (44.27%), Postives = 221/384 (57.55%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L+ L   QI   E+   I+S +GRVY   + ++             P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   V+KV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  417 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNSD----------TLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSSCS 780

HSP 7 Score: 136.732 bits (343), Expect = 5.659e-30
Identity = 91/264 (34.47%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + +V +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 4059 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 4315

HSP 8 Score: 118.242 bits (295), Expect = 2.420e-24
Identity = 91/265 (34.34%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  ++V +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3951 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4215

HSP 9 Score: 106.686 bits (265), Expect = 7.286e-21
Identity = 170/685 (24.82%), Postives = 281/685 (41.02%), Query Frame = 2

Query: 4667 IIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAYKAALMLKK---PKK--STDYWQIVYN---------------FVMKKFAGKIRQNKSAAIKLVDNSENIREF----------------CGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCD-KVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLLVNDQK-----IESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSD--SRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAG---QLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTL-ITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKLI 6559
            +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L++ P   RW+ IA K     +K   PKK  STD  + + N                 + K    I+  K     L+     + ++                   I +F L +E +D++K+R  +L +    +++ + +  ILK     L     LLP VQ ++   FC  +  I +  + G   E + D LK  + +  FN + L        T   L   ++Q +R  L+    K     I+ +    + N       +G    A+  L + + L  T+    +   LLL +G+L L QT LR        LI   C +        +   S  +  ET K  +   L  S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L         E P+                   A +   ++++T  +S+ +     + P+A +F S  N    L L SAG   ++MQ+ + + L                      LL  L+   +   +   N   + +Y+EQ   WC   F+ ++ +T       +S  WI L +K  E     ++T ++  QIL + +L+ ++
Sbjct: 1491 LIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIMSKFKL-----------LSSLP---RWRRIAQKIIRERRKKRVPKKPESTDDEEKIGNEESDLEEACILPHSPINVDKRPIAIKSPKDKWQPLLSTVTGVHKYKWLKQNVQGLYPQSPLLSTIAEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILK-----LASKNFLLPSVQYAM---FCGWQRLIPEGIDIG---EPLTDCLKDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRNVLMDASAKFKELGIQPVPLQTITNENPSGPSLGTIPQARFLLVMLSML--TLQHGANNLDLLLNSGMLALTQTALR--------LIGPSCDNVEEDMNASAQGASATVLEETRKETAPVQLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLA--------ELPA-------------------AAQPSAEDSDTEDDSEAEQTERNIHPTAMMFTSTINLLQTLCL-SAGVHAEIMQSEATKTL--------------------CGLLRMLVESGTTDKTSSPN---RLVYREQHRSWCTLGFVRSIALTPQVCGALSSPQWITLLMKVVEGHAPFTAT-SLQRQILAVHLLQAVL 2081

HSP 10 Score: 102.834 bits (255), Expect = 1.043e-19
Identity = 64/209 (30.62%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D ++V   S +S+ L K G VY+W K
Sbjct:  480 DTLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGK 683

HSP 11 Score: 97.0561 bits (240), Expect = 5.287e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4042 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4271

HSP 12 Score: 84.7297 bits (208), Expect = 3.031e-14
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3058 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3231

HSP 13 Score: 84.3445 bits (207), Expect = 4.096e-14
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  604 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 740

HSP 14 Score: 83.1889 bits (204), Expect = 1.011e-13
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  625 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGL 758

HSP 15 Score: 82.0333 bits (201), Expect = 2.240e-13
Identity = 61/205 (29.76%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  VVK  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  571 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACG 769

HSP 16 Score: 80.4925 bits (197), Expect = 5.394e-13
Identity = 47/136 (34.56%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RV+D+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4143 HRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4274

HSP 17 Score: 76.6406 bits (187), Expect = 9.518e-12
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3100 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3282

HSP 18 Score: 76.2554 bits (186), Expect = 1.125e-11
Identity = 44/136 (32.35%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+DV A    +H   VT AG +Y+WG    G+LG  D++D+ +P +++   + H +V  +AC  G+  +L LT    ++S G    G+LG G      +P++I +  L G+ V ++      S+ L+  GA++TWG
Sbjct: 4093 VVDVAAG--GAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEAL-QGH-RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGLGVVKVECGSQFSVALTKSGAVYTWG 4222

HSP 19 Score: 75.8702 bits (185), Expect = 1.411e-11
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct: 3035 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3281

HSP 20 Score: 73.9442 bits (180), Expect = 5.803e-11
Identity = 68/241 (28.22%), Postives = 106/241 (43.98%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVSMISK----------------GDGEFYFLDKSG 2293
            A T   +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +Y+CG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+  S+                GDG+F  L + G
Sbjct: 2954 AATIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLG-ISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3189

HSP 21 Score: 63.1586 bits (152), Expect = 9.396e-8
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 3997 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 4116

HSP 22 Score: 57.3806 bits (137), Expect = 5.721e-6
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3211 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3325

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. UniProt/SwissProt
Match: sp|Q4U2R1|HERC2_MOUSE (E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 GN=Herc2 PE=1 SV=3)

HSP 1 Score: 998.038 bits (2579), Expect = 0.000e+0
Identity = 596/1325 (44.98%), Postives = 801/1325 (60.45%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPRE-----FSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+       + S+  +L  SL+  A     L    R+WA++++  ++         +F ++I+   +L     +S+ L+           F   A                      +   +  L + + +QF++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC+  R   +L   + LP  F++E              + ++I  + A SE  D        F  + D Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP  CE L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++D+AAGG+HSA ++ +G+LYTWGKGRYGRLGH + +DQ  PK+VEAL+G+ VI +ACGSGDAQTLC+T ++          +VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK +NRVACGSAHTLAW+T     +   + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL           SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK +GESVDDCGGGYSESI EIC+ELQNG  P  I +P        ++DC++L+P      +   F FLG LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V +  G+++ L   +S    +   NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+G++    ++ WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FVIQVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3614 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVSVRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------VLSCPSMDLVTCLLDFRLNLTSNRSIVPRLAASLAACA-QLSALAASHRMWALQRLRRLLTT-------EFGQSININRLLGENDGESRALS-----------FTGSA----------------------LAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDE--------------VAKKIRELMADSESMDVLHESHSIFKREQDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDD----------TVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWST--SKPASAGKLPAQ------VPMEYNHLQEIPIIALRNRLLLLHHISELFCPCIPMFDLEGSLDETGLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLNPATRAPVHCSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQL---SSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4804

HSP 2 Score: 480.33 bits (1235), Expect = 9.509e-134
Identity = 250/418 (59.81%), Postives = 306/418 (73.21%), Query Frame = 2

Query: 9413 IMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGA 10666
            I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF VT  GKVY  G+++NGRLG+G    +++  +  P+++ AL  Y + KVAVHSGGRHA ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAA+   G LYTWGLG+YGRLGHGD   +L P++VK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHG+D H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   DPLGA
Sbjct: 2958 IRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG----MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVAT----------PSVHE-----------PVLFQTARDPLGA 3350

HSP 3 Score: 374.4 bits (960), Expect = 1.045e-101
Identity = 195/393 (49.62%), Postives = 267/393 (67.94%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVDVA G +HSA +   G LYTWG G YGRLGH D+  +L P+LV++L+ ++V+ +ACGS DAQTL LT D TVWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   K+  VACGS+H++AW+ S   S   LP+Q    + H++E+
Sbjct: 3956 IYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSKPASAGKLPAQVPMEYNHLQEI 4343

HSP 4 Score: 356.295 bits (913), Expect = 2.651e-96
Identity = 206/382 (53.93%), Postives = 268/382 (70.16%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+++G+VY+ G   NGRLG+G S+ +V  P  ++ L   +V KVAV+SGG+H  AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAA++ SGELYTWG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHGSD HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLGMSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3328

HSP 5 Score: 285.419 bits (729), Expect = 7.958e-75
Identity = 161/377 (42.71%), Postives = 227/377 (60.21%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     +G +  + V  PI  E L+ L  + ++   K    ++R G+VY    +S+               ++ P+ ++ L    IVK+A HS G H +AL   GE +SWG GD G+LGH   + L  P+ I  F GK+    VV +ACGS++SAAI   G LYTWG G+YGRLGHG +     P LV  L+  KV+ VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ IE +   +VI++ CG+Q S ALT++GQV++WGKGD  RLGHGT++H+R P  +E L+  K++ +A G+ HCLA+T+  +V+SWG ND  Q  +        PT +  L    I  +ACG + S AW++
Sbjct:  423 LQEVIGWGL-----IGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD---------------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSS 779

HSP 6 Score: 264.618 bits (675), Expect = 1.588e-68
Identity = 170/384 (44.27%), Postives = 223/384 (58.07%), Query Frame = 2

Query: 12464 NHRGQLGGVEG---------SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +H+G L  V G         + +  P+ CE L++L   Q+   E+   I+S +GRVY   + ++          +  P LV GL  + +VK+A +S G H LAL   G VY+WG  +  +LG    V   E  +            ++ IA G ++SAAI+  GELYTWG+G YGRLGHG+ +D+  P +V  L+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  IE L+   VIKV CGSQFS+ LT  G+VY+WGKGD  RLGHG++ HVR P+ +  L  KK+IDVA GS HC+  TED EV+SWG ND+ Q  D    T   P  +  L  K I  +ACG A + AW++ S
Sbjct:  418 SHKGSLQEVIGWGLIGWKYYANVIGPIQCEGLASLGVMQVACAEKRFLILSRNGRVYTQAYNSD----------MLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTEN----------GQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACGPAQSFAWSSCS 781

HSP 7 Score: 136.346 bits (342), Expect = 7.779e-30
Identity = 90/264 (34.09%), Postives = 130/264 (49.24%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V ++ G     CVT  G +Y  G    GRLG     D      + PK +EAL  + ++ +A  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    V ++ CG+  + A
Sbjct: 4061 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSED-----QLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLA 4317

HSP 8 Score: 117.857 bits (294), Expect = 3.163e-24
Identity = 90/265 (33.96%), Postives = 131/265 (49.43%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ +  G   S  +T  G ++TWGKG Y RLGH   +   +P  +E L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3953 SGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4217

HSP 9 Score: 102.834 bits (255), Expect = 9.758e-20
Identity = 65/209 (31.10%), Postives = 108/209 (51.67%), Query Frame = 2

Query: 1559 DCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK 2164
            D L    V  L S+N ++ + A+    H LA+   G+VYSWG    G+LG GDT   + P +I  FS  +    V  +ACG  +S  +T  G++Y+ GR + G+LGHG  +D  +P+ +     + V+         Q++ ++ +G +++WG   +    R  S+   +PK+     E   ++D I+V   S +S+ L K G VY+W K
Sbjct:  481 DMLAPQLVQGLASRN-IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKL----IEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGK 684

HSP 10 Score: 98.2117 bits (243), Expect = 2.596e-18
Identity = 143/519 (27.55%), Postives = 214/519 (41.23%), Query Frame = 2

Query: 4667 IIKRHQQTCISYKELCSNINIRCRFLIDEVE--------ILS-------------INNSAINAGRKKSI-----------NINDFTSDH-----LTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGK-IRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCD-KVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLL-----VNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWC---QDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL-------KKSIEDVKNETPSEC--GVRSLMKDISML 6037
            +IK HQ+   SYKE+C+ +  R RFL +E+         I+S             I    I   RKK +            I +  SD      L  +P     + I+      +K PK   D WQ + N V      K ++QN       V            I +F L +E +D++K+R  +L +    +++ + +  ILK     L     LLP VQ ++   FC  +  I +  + G   E + D L+  + +  FN + L        T   L   ++Q +R  L+       +  I+ +    + N       +G    A+  L + + L  T+    +   LLL +G L L QT LR        LI   C   +D  N       S  +  ET K  +   L  S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L       + S ED   E  SE   G R++     ML
Sbjct: 1492 LIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCSDLSIMSKFKLLGSLPRWRRIAQKIIRERRKKRVPKKPESIDSEEKIGNEESDLEEACVLPHSPINVDKRPIS------MKSPK---DKWQPLLNTVTGVHKYKWLKQN-------VQGLYPQSALLNTIVEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILK-----LAAKSFLLPSVQYAM---FCGWQRLIPEGIDIG---EPLTDCLRDVDLIPPFNRMLLEV------TFGKLYAWAVQNIRSVLMDASARFKELGIQPVPLQTITNENPAGPSLGTIPQARFLLVMLSML--TLQHGANNLDLLLNSGTLALTQTALR--------LIGPTCDSVEDDMNAS-ARGASATVLEETRKETAPVQLPVSGPELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTGSTNSYRMGKEGKYDLKLVELPVSSQPSAEDSDTEDDSEAEQGERNIHPTAMML 1965

HSP 11 Score: 96.6709 bits (239), Expect = 8.238e-18
Identity = 79/244 (32.38%), Postives = 115/244 (47.13%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  VA G  HS  +T +GD+Y+ G+   G+LGH D +D+  P  + A  L G  V  IA      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4044 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEA--LQGHRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4273

HSP 12 Score: 84.7297 bits (208), Expect = 3.408e-14
Identity = 56/178 (31.46%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H  A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  LT SG++Y+ G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3059 HATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3232

HSP 13 Score: 83.9593 bits (206), Expect = 5.135e-14
Identity = 51/142 (35.92%), Postives = 73/142 (51.41%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCR 2029
            +VIDV      +  LAVTE GQV+SWG    GKLG+G +   K P +I+      L V +V CG + S+ LT+ G +YS G+    +LGHG   + H+        L G  V  +A      + L+ D  + +WGS  D C+
Sbjct:  605 KVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQ--DLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHG--TEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSN-DQCQ 741

HSP 14 Score: 82.8037 bits (203), Expect = 1.109e-13
Identity = 51/136 (37.50%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL 12850
            +VWSWG    G+LG       K P L E L  L   ++  G Q    ++ DG+VY+ G G+N RLG G+ E V+ P L+ GL+ K V+ VA  +G  HCLAL  +  V++WG  +  +    +RV   E    P L
Sbjct:  626 QVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVA--AGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGL 759

HSP 15 Score: 82.0333 bits (201), Expect = 2.221e-13
Identity = 60/205 (29.27%), Postives = 108/205 (52.68%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII--GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            E+++WG  + G+LG        +P+L   L  L+   +    G+     V+ +G+V++ G G+ G+LG G ++  +TP L+  L++  V+K  V  G +  +AL  +G VY+WG  ++ +LG        E V  P L++ L   ++ID+AAG +H  A++   E+++WG     +        +P P  +  L   H++G+ACG
Sbjct:  572 ELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVIK--VRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPTALPGLDSKHIVGIACG 770

HSP 16 Score: 81.2629 bits (199), Expect = 3.859e-13
Identity = 48/136 (35.29%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVID+      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4145 HRVIDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4276

HSP 17 Score: 76.2554 bits (186), Expect = 1.035e-11
Identity = 53/197 (26.90%), Postives = 91/197 (46.19%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  L+  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3101 RIRDIACGSSHSAALTSSGELYTWGLG----------EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--SDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3283

HSP 18 Score: 75.8702 bits (185), Expect = 1.696e-11
Identity = 70/262 (26.72%), Postives = 115/262 (43.89%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTW 2158
            +PR++     + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++Y+WG    G+LG GD   + +P ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG        H S+   +    V   R  +I  + V       +  SG VY W
Sbjct: 3036 IPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3282

HSP 19 Score: 73.1738 bits (178), Expect = 9.668e-11
Identity = 67/235 (28.51%), Postives = 104/235 (44.26%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVS----------------MISKGDGEFYFLDKSG 2293
            +V+ WG N   +LG       K P+  +T S   L V QVA G +    +T  G +YSCG    G+LG G +    +PI    + L   +VK++AV   G  +  L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + L  SG +YTW L         D+   ++P++   +L ++V  V+                + S GDG+F  L + G
Sbjct: 2961 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSKSLFAVTVEGKVYSCGEATNGRLGLG-MSSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3190

HSP 20 Score: 63.1586 bits (152), Expect = 1.005e-7
Identity = 44/124 (35.48%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+      P R+  S L G+ V  +A  G  S C++  G ++TWG
Sbjct: 3999 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGIEVVDVAAGGAHSACVTAAGDLYTWG 4118

HSP 21 Score: 56.9954 bits (136), Expect = 6.651e-6
Identity = 34/123 (27.64%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H +  H    ++   V++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3212 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3326

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. UniProt/SwissProt
Match: sp|Q9VR91|HERC2_DROME (Probable E3 ubiquitin-protein ligase HERC2 OS=Drosophila melanogaster OX=7227 GN=HERC2 PE=1 SV=3)

HSP 1 Score: 923.309 bits (2385), Expect = 0.000e+0
Identity = 563/1377 (40.89%), Postives = 782/1377 (56.79%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNE--IELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVS---------------TAD--EWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLK-----------EPTVKDP------------------------LTREINAI---------TAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGK---LIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSP-YADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETE--LENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +++ES HPY +N  ++G V IP A  L +EFD QCSTE+  D LVIMD    ++A RSG+ +  W  ++ + G+EL W F SD S+  WGWRF V         + I    T     ++   L  P++ L+  LL+      Q          + + SQ+      L    RIW++R++ A++                              L  Q   P +P+                            +   L  L   +L+Q+++EEP+V+    L +S + K+L  L+C ++LD+  P +               T D  +WAWF+ YC+  R  +SLI  + LP  F  E + +F +            P  + P                        +T E   +         T+   + D   F   HD Q++ WL  RPD W   W         ++ WGHNHRGQLGG+EGS+IK P  CE LS LRP Q+ GGEQSLF V+ DG+++ATG+G+ GRLG+G ++S   P L+  L+   V KVAVNSGGKHCLAL   G VYAWG+ ED KLG   R+        P LV+ L    + DIA G +HSAAI+ SG + TWGKGRYGRLGHG+ +DQ  PK+VEAL GY  I +ACGSGDAQTLCIT +++          VWSWGDGDYGKLGRGG D CKLP KIE+L G GV+KV+CGSQFS+ LT SG VYTWGKGD+ RLGHGS +HVR+P+KVA L  KKII +A GSLHC+ C++ GEVY+WGDNDEGQLGDGT T   RPR++ +L GK I +V CGSAHTLA +T        ++  ++   L   P   +L+ + +  +L  R +LLHH++EL C  L  + ++    +  ++ +L+ + KE+ FR ++QTTM   K+HGP I++NR+                             + + + C G   I   K+VFGQ+  K   L +EA                  LP+RVWKVK +GESVDDCGGGYSESI E+CDELQNG +P  I++P        ++DCF+L P  +       F FLG L+GIA+RT  PLS+ +++ +W+ L+G+ L   DL   D+D ++ L+ ++ +D+       L++P+S ++  G EV L+   +    ++  NR  Y+   + +++HEFD+    +R G+S VIP+PLL+LFS+ EL+ +VCG+  IP+  LKS+  Y+G      ++ WFWE+MEE TN+ RSLFLRFVWGRTRLPR ++D RG++FV+QVL K +P D +LPE+YTCFFLLK+P YS KA+L EKL YAIHFCKSID D+YAR+A+ 
Sbjct: 3658 VMQESSHPYVDNVNVTGVVRIPGAEMLRLEFDSQCSTEKRNDPLVIMDGTGRVLAMRSGREFAHWAPEIRVLGDELRWKFSSDSSVNGWGWRFWV---------HAIMPAATLGESGSDRAVLSQPSMALVMSLLDSRLAPRQPSVLLRLASALAACSQLGA----LTTAQRIWSLRKLHAVL------------------------------LLEQAPRPQDPS----------------------------LSTLLQPLIPELLRQYEYEEPQVRGGIHLMHSDYFKTLAALACDMQLDAALPATSSSSSSSAAPGAISSTGDVHKWAWFKRYCIAVRVAQSLIRRTELPRAFCLEVRKKFAEMLPSSSSNSNANPGCQSPGASMLNSTTSLSSSTVSNVSPPPGITGEQPDLHCHAHQLESTSTLLHEDHTLFQAPHDAQLLQWLNRRPDDWALSW----GGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRM----SYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDN----------VWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALST--------SQLSERLRPLPNPPLEYDLVRDLAPEALHARLILLHHFSELVCPCLAMLPISGDLSLGALKDVLVYNIKEAAFRKVIQTTMVRDKQHGPVIELNRIQV---------------------------KRSRNRCNGLAGIDGMKSVFGQMVQKLPLLTQEA----------------LALPHRVWKVKFVGESVDDCGGGYSESIAEMCDELQNGSVPLLINTPNGRGEAGANRDCFLLDPTLSSVLQMNMFRFLGVLMGIAVRTGSPLSINLAEPVWRQLTGEVLRPTDLTEVDRDYVAGLLCIRNMDDDPKLFTALELPFSTSSARGHEVPLSTRYT---HISPRNRAEYVRLALGFRLHEFDEQVKAVRDGMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYKGFDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADFRGRDFVLQVLEK-NPPDHFLPESYTCFFLLKMPRYSCKAVLLEKLKYAIHFCKSIDTDEYARVAMG 4890

HSP 2 Score: 433.721 bits (1114), Expect = 1.053e-119
Identity = 225/396 (56.82%), Postives = 286/396 (72.22%), Query Frame = 2

Query: 9341 PTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAW 10528
            P + +   + +T   +  +  +  +   + VWGLNDK+QLG    SKVK+P  ++ +S L  + I+GGSKSLF V++ GKVY  G+ +NGRLG+G    +T  V + P +L  L +Y + KVAVHSGG+HA+ALT +G+ FSWGEG+DGKLGH +R  L+ PR ++  + K++ DVACGSSHSAAI   G LYTWGLG+YGRLGHGD   +L P+LV +L   +VVQVACGSRDAQTLALT D  V+SWGDGDFGKLGRGGS G   P +IE +S   V+QIECGAQ S ALT  G+VWTWGKGDYYRLGHG D+H+R+P  I  L+  +++H+AVGALHCLAVTD GQVY+WGDNDHGQQG+G    N +P LV  L    +  VACGSSHS+AW
Sbjct: 2960 PGSTAGAGAVSTSHEEAAAAPEQDLPCTVMVWGLNDKEQLGGLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLG----VTHNVPL-PHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIAW 3350

HSP 3 Score: 362.459 bits (929), Expect = 3.454e-98
Identity = 193/379 (50.92%), Postives = 262/379 (69.13%), Query Frame = 2

Query: 9419 SKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFL 10555
            S IY WG N + QLG    S++K P   EALS L  V ++GG +SLF VT  GK++  G  S GRLG+G         ++G     +L   F+ KVAV+SGG+H +ALT  GE ++WGEG+DGKLGH +R+  + P+ +++  G  V D+ACGS+HSAAI   GH+ TWG G YGRLGHGD+  +L P+LV++L  Y+ + +ACGS DAQTL +T D  VWSWGDGD+GKLGRGGS GC +P KIE ++   V+++ECG+Q S ALT++G V+TWGKGD++RLGHG+  H+R P ++  L+  KI+ +A G+LHC+A +D G+VY+WGDND GQ G+GTVT   RP LV+AL    I  V CGS+H++A + S L   L
Sbjct: 4049 STIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLG-----SLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQLSERL 4422

HSP 4 Score: 352.443 bits (903), Expect = 4.003e-95
Identity = 203/391 (51.92%), Postives = 264/391 (67.52%), Query Frame = 2

Query: 12446 VWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESP 13618
            V  WG N + QLGG++GSK+KVP   + +S LRP  I GG +SLFIVS DG+VYA G G NGRLG+G T +V  P  +  L + +V KVAV+SGGKH LAL  +G V++WG+ ED KLG   R      +  P LV++L   +I D+A G SHSAAIS  GELYTWG G YGRLGHG+   Q  PK+V AL G  V+ VACGS DAQTL +T++           +V+SWGDGD+GKLGRGG +    P +IE L G GV++++CG+QFSL LT +GEV+TWGKGDY+RLGHG D HVRKP+ +  L  +++I VA G+LHC+  T+ G+VY+WGDND GQ G G T  N +P ++  L    +NRVACGS+H++AW   + +   E   P
Sbjct: 2988 VMVWGLNDKEQLGGLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRT----TLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTED----------GAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIAWGLPNASSDEEKRGP 3364

HSP 5 Score: 180.644 bits (457), Expect = 3.370e-43
Identity = 120/298 (40.27%), Postives = 171/298 (57.38%), Query Frame = 2

Query: 9662 PKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-TDKHIRE---PMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYN--MRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            P  +E +     + +A H  GRH +A+  N   +SWG G+D +LGH        P KI   +   V  V CG S+SAAI  GG+L TWG G Y RLGHG++  R  P LV +L D+ VV VA GS DA +LALTS+  V++WGDGD+GKLG G  +G L P  +E  SL  V ++  G+Q S AL+  GQ++TWGK     LGH   ++ ++    P  +  L+  +IV +AV   HCLA++  G+V+ WG ND  Q    +V+    +R  ++ +L     + +AC S+ S+ WT S
Sbjct:  605 PLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVE--SLPRVQRVFAGSQFSVALSSEGQLYTWGKATC--LGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWTQS 898

HSP 6 Score: 149.058 bits (375), Expect = 1.039e-33
Identity = 125/354 (35.31%), Postives = 186/354 (52.54%), Query Frame = 2

Query: 12548 RQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-DIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHG----SDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNS--RPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            +Q+   E  + I+S +G++Y        RL     E    P+ +  +   + + +A +  G+H LA+ +N   Y+WG  ED++LG  D   +       PT + +L +  +  +  G S+SAAI+  G L TWG+G Y RLGHGN DD+  P +V AL  + V+ VA GSGDA +L +T              V++WGDGDYGKLG G  +    P+ +E+L    V +V  GSQFS+ L++ G++YTWGK     LGH     S      P  V+ L  K+I+DVA    HC+  +  GEV+ WG ND  Q+   + ++    R  I+ SL     + +AC SA +L WT  S
Sbjct:  575 KQVACCETQMLILSQEGKLY------TWRLAKPEAE----PLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHAR-----AVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTS----------EGLVFAWGDGDYGKLGNGNCNGSLQPILVESL--PRVQRVFAGSQFSVALSSEGQLYTWGKATC--LGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWTQSS 899

HSP 7 Score: 106.686 bits (265), Expect = 6.769e-21
Identity = 94/273 (34.43%), Postives = 135/273 (49.45%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLV 13261
            +V+SWG    G+LG    + +  P L E L A + R +  G      +S  G +Y  G G  GRLG G   +   P LV+ L  + VV+VA  S     LAL  +G V++WGD +  KLG       G D  TP  ++ L    ++ I  G   S A++R+GE++TWGKG Y RLGHG       P+ +  LRG  VI VA G+      C+   +  +        V++WGD D+G+ G G   + K P  +  L+   V +V CGS  S+ 
Sbjct: 3093 KVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRG--GSEGSD--TPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGA----LHCLAVTDAGQ--------VYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIA 3349

HSP 8 Score: 96.2857 bits (238), Expect = 9.276e-18
Identity = 71/229 (31.00%), Postives = 111/229 (48.47%), Query Frame = 2

Query: 9854 RVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            ++  VAC  +    +   G LYTW      RL   +      P  ++ +     + +A        LA+ S+   +SWG G+  +LG G +    +P KI  +    V  + CG   S A+T  G + TWG+G Y RLGHG       P  +  L    +V +A+G+   H LA+T  G V++WGD D+G+ GNG    +++P LV +L   ++  V  GS  SVA ++
Sbjct:  573 QIKQVACCETQMLILSQEGKLYTW------RLAKPEA----EPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESL--PRVQRVFAGSQFSVALSS 789

HSP 9 Score: 95.5153 bits (236), Expect = 1.827e-17
Identity = 65/195 (33.33%), Postives = 100/195 (51.28%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWGS-TFDNCRRHLSNWSPKIETCVNEYRNE----IDQIQVH-DSTYSV-LLKSGSVYTWLK 2164
            V  V  N    H LA+T  G+VY+WG    GKLG G+     RP +++  +   + V  +ACG  HS  +T SG + + G+   G+LGHGD +D+  P  + A  L+G     IA      Q++C+++D  +++WG   +    R  S      + C   Y+ E    +  ++V   S +SV L KSG+VYTW K
Sbjct: 4136 VKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLN--GMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEA--LLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGS------DGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGK 4320

HSP 10 Score: 88.5817 bits (218), Expect = 1.950e-15
Identity = 74/256 (28.91%), Postives = 117/256 (45.70%), Query Frame = 2

Query: 1406 LNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSR-CHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITA-SDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKS-GSVYTWLK 2164
            L+ +F+IK++ C      +LS  G LY    +  +                + L  + V    + +  I +  +    H LA+      YSWGT    +LG GDT  R  PT I    + C   V+ V CG  +S  +T  G++ + GR    +LGHG+  DR LP  + A SD + V V   + D H S+ L+++G +F WG   D  +    N +  ++  + E    + ++    S +SV L S G +YTW K
Sbjct:  568 LSCRFQIKQVACCETQMLILSQEGKLYTWRLAKPEA---------------EPLPMEEV----AHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPTKIAALEQHC---VQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAH-SLALTSEGLVFAWGDG-DYGKLGNGNCNGSLQPILVESLPRVQRV-FAGSQFSVALSSEGQLYTWGK 798

HSP 11 Score: 79.7221 bits (195), Expect = 1.073e-12
Identity = 45/135 (33.33%), Postives = 70/135 (51.85%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            R ID+      +  L +T+   V+SWG    GKLG+G +   K P  I++ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG V     P ++ A  L G  +  IA      +  S+ G ++TWG
Sbjct: 4241 RAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLA--GLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAA--LQGKKIISIATGSLHCVACSDSGEVYTWG 4371

HSP 12 Score: 78.1814 bits (191), Expect = 2.856e-12
Identity = 44/135 (32.59%), Postives = 72/135 (53.33%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RV+ V      +  LA+TE G V+SWG    GKLG+G ++    P  I+  S   + V Q+ CG + SL LT++G++++ G+    +LGHG   D+H+        L G  V  +AV     + +++ G ++ WG
Sbjct: 3178 RVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLS--GIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGG--DQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTDAGQVYAWG 3308

HSP 13 Score: 77.7962 bits (190), Expect = 4.127e-12
Identity = 43/127 (33.86%), Postives = 67/127 (52.76%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            SSH  A++  G++Y+WG    G+LG GD   + +P ++   +    +V QVACG  +  +L LT+ G ++S G    G+LG G  +    P  I    L G+ V QI      S+ L+  G ++TWG
Sbjct: 3134 SSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALA--GRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEI--ERLSGIGVVQIECGAQFSLALTRAGEVWTWG 3256

HSP 14 Score: 70.4774 bits (171), Expect = 5.564e-10
Identity = 54/202 (26.73%), Postives = 94/202 (46.53%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNC------RRHLSNWS-PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTE--CNKSDDIQPELDT 2215
            S+  A+T  G + +WG  T  +LG G++ DR  PT++   S   +    +  G+ HSL LT  G +++ G    G+LG+G+      PI + +       V+++      S+ LS++G ++TWG     C       R +   S P++ + +   R  I  + V  +    L  SG V+ W +  ++  C  S   +P L T
Sbjct:  678 SYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLP----RVQRVFAGSQFSVALSSEGQLYTWGKA--TCLGHQLVERSVQGCSVPRLVSSLQHKR--IVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRT 871

HSP 15 Score: 67.0106 bits (162), Expect = 6.461e-9
Identity = 64/254 (25.20%), Postives = 108/254 (42.52%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVD--GHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYR-NEIDQIQVHDSTYSVLLKSGSVYTW----LKYCTECNKSDDIQPELDTVLKYQ-----------------VDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIK 2359
            V  WG N   +LG       K PT   T SR  L+   +A G +   I++Q G +Y+CG    G+LG G   +  LP ++    L   +VK++AV   G  ++ L+ DG +F+WG   D    H +  +      V   R  +I  +    S  + +   G +YTW           + +  ++P+L T L  +                  ++ ++ S GDG+F  L + G   +    +I   + SG G ++
Sbjct: 2988 VMVWGLNDKEQLGGLKGSKVKVPTFSQTISR--LRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPV--LRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEI--ERLSGIGVVQ 3235

HSP 16 Score: 66.2402 bits (160), Expect = 1.241e-8
Identity = 48/178 (26.97%), Postives = 82/178 (46.07%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            S  +  V++ G+VY+ G  T+G+LG G T +   P  +    +  ++   V  G +H+L LT  G ++S G    G+LGHG+      P  + A  L    ++ +A     S  +S+ G ++TWG        H  N +   PK+ T +   R         D+    L + G+V++W
Sbjct: 3028 SKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEA--LRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSW 3203

HSP 17 Score: 65.855 bits (159), Expect = 1.582e-8
Identity = 69/304 (22.70%), Postives = 131/304 (43.09%), Query Frame = 2

Query: 9185 ISNDILLKTIFSISDKNWSAEDIDTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVEN-QDNSKFKSRIM--SKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSL--FCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHN----SRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMR--LHPELVKSLRDYKVVQVACGSRDAQTLALT 10063
            +++D+ +        +++ A D     N+  Y+W     ++L    +++     T    L ++ V++      + + I     +  WG     +LG   +    LP L  ALS+   V ++ GS       +T  G V+  GD   G+LG G+       +++  + L  + + F       +G + ++AL+  G+ ++WG+     LGH     S    + PR +   + KR+VDVA   +H  A+   G ++ WG  D  ++     +    L   ++ SL  +    +AC S  AQ+L  T
Sbjct:  611 VAHDVFISIAGHCEGRHFLAID----SNHNAYSWGTGEDHRL-GHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILV--ESLPRVQRVF-------AGSQFSVALSSEGQLYTWGKAT--CLGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTS--AQSLVWT 896

HSP 18 Score: 64.3142 bits (155), Expect = 4.282e-8
Identity = 46/154 (29.87%), Postives = 68/154 (44.16%), Query Frame = 2

Query: 5762 LPSQLKKGTLVLRGRDWKYGDQDG--PNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISI 6217
            L   +K GT ++RG DWK+GDQDG  P    I+     +G VRV+W     T SYR GK+  YDL+L  S  +V + T  E                           E ++ S+               P++ + PS LL H A +L+Q +++
Sbjct: 1921 LAKLMKIGTRIVRGADWKWGDQDGNPPGEGRIISEVGEDGWVRVEWYTG-ATNSYRMGKEGQYDLQLADSALNVASPTEPE--------------------------REDVSGSEAS-------------PTSDSHPSKLLRHCAAKLLQILAV 2034

HSP 19 Score: 63.1586 bits (152), Expect = 9.095e-8
Identity = 43/140 (30.71%), Postives = 73/140 (52.14%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGR-NHMG-QLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S + V+DV      +H LA+T  G V++WG    GKLG G+     +P ++++  R    V++V  G + S+ L+  G +Y+ G+   +G QL    V+   +P R+ +S L    +  +AV     + LS+ G +F WG
Sbjct:  718 SDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLPR----VQRVFAGSQFSVALSSEGQLYTWGKATCLGHQLVERSVQGCSVP-RLVSS-LQHKRIVDVAVSVAHCLALSSSGEVFGWG 851

HSP 20 Score: 59.6918 bits (143), Expect = 1.248e-6
Identity = 37/117 (31.62%), Postives = 57/117 (48.72%), Query Frame = 2

Query:  485 LGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTDTLPFWSGVTEQTYQFLKNTVLC-PSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLK 832
            L  V   + +   F F++R WR G   D + C E++  A+  +QE+P A  F  +  +     W  V E++ +FL+   L  P  N    P   R  AL LLLE+G+  G L+  L+
Sbjct:  303 LARVATHAALNFSFAFLRRAWRSGE--DTEMCSELLSEALASLQELPEATLFEAAVVSS---LWLEVMERSIKFLRLVALGDPMGNRCTAPLNDRHTALCLLLELGVQKGTLAATLE 414

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. UniProt/SwissProt
Match: sp|Q15751|HERC1_HUMAN (Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens OX=9606 GN=HERC1 PE=1 SV=2)

HSP 1 Score: 445.277 bits (1144), Expect = 3.395e-123
Identity = 343/1101 (31.15%), Postives = 542/1101 (49.23%), Query Frame = 2

Query: 11966 INDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSI---------------SPVS-TADEWAWFRNYCLTYRTTESLITNSSLPYRF-INEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWK---KCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSL-STRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL--NRQS------------VMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYAD-KTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET----ELENLQIP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            +N    +  FL  L  ++ +Q+ +E+P V    QL +S +++ L  L+  + LD +                P S   +EWAW   +  T +  E+L   +  P  F + +       EP  +D L   +          D  ++    D QI+ W  SRP+ W    KC         +V+ WG    GQL    G  + VP      S  + +Q+I G+   F++  +G V A G G+ GRLG G+++ +    ++S L+  +V ++  + G   H +AL  +G V++WGD +  KLG        +    P  +++L   E++ ++ G  HSA ++  G+L+T+G G YGRLG GN  ++  P+ V AL GY +  VACG     TL ++ +          + VW++GDGDYGKLG G       P KI+ L G G+ KV CG+QFS+ LT  G VYT+G+     L  G   +  +P+++  L    I DVA G+ H +    +G+VY+WG N EGQLG G T     P ++  L GK + +++ G  H+ AWT           S   +L L  T P     L   S  ++  R  LL+H+++L  S+   ++L  N Q+            V  ++R +L P          +  TM   K +GP+I V R+                                G  C         K +F Q+  ++++    ++ S            LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I SP        ++D F+ +P A    +   F FLG L+G+AIRT +PL L ++ L+WK L    L   DL+  D   + +L S+  I+++    E  +  IP   +   + DGK V + I    +I +  SNR  Y++  I Y++HE D+    +R G+S ++P+PLL+L ++++LE +VCG   I +  LK +  YR V     ++ WFW  +EE +NE R LF+RFV GR+RLP   +D+  +  +++V   Y    D LP + TCFF L+LP YSS+ ++ E+L YAI+ C+SID+D+Y
Sbjct: 3844 LNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQNCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDL------EPVPEDELVFLM----------DNSKWINGMDEQIMSWATSRPEDWHLGGKC---------DVYLWGAGRHGQLAEA-GRNVMVPAAAPSFS--QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHG----NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLN--HTLAVSAD---------GSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGALREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRIST-----------------------------RGRKC---------KPIFVQIARQVVK----LNASD---------LRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPI-IPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPY----DSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNY 4845

HSP 2 Score: 232.646 bits (592), Expect = 6.097e-59
Identity = 146/380 (38.42%), Postives = 211/380 (55.53%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFT-VWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLP 10558
            +Y+WG     QL  EA   V +P    + S+   V    G    F +   G V   G+ S GRLG G+  D+    +I      AL  + + ++    G   H++ALT++GE FSWG+GD GKLGH +  +   PR+I+  +G+ VV ++CG  HSA +   G L+T+G GDYGRLG G+T+ +  PE V +L  Y++ QVACG     TLA+++D + VW++GDGD+GKLG G S+    PQKI+ +    + ++ CG Q S ALT++G V+T+G+     L  G  ++   P QI  L    I  +AVGA H LA+   G VY+WG N  GQ G G   +   PTLV+ L    +  ++ G  HS AWTA  +    P
Sbjct: 3999 VYLWGAGRHGQLA-EAGRNVMVPAAAPSFSQAQQVIC--GQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVI-----SALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLN--HTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWTAPPVPPRAP 4368

HSP 3 Score: 226.098 bits (575), Expect = 6.974e-57
Identity = 154/379 (40.63%), Postives = 210/379 (55.41%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIK-YFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSD-FTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            ++YVWG N   QL      K+  P L  + S  D  +I  G    F ++  G V   G  S GRLG+G   + +       K+L       I KV+   G   H +A T  GE FSWG+GD GKLGH +     YP+ I+   +GK VV V+ G  HSAA+   G LYTWG GD+GRLGHGD+  R  P LVK + +  V +V+CGS  + T+AL+ D  TVWS+G GD GKLG G ++    P+ IE +    + ++  G+QSS ALT  GQV+ WG G     G      +R P  IE+L  T+IV +++G  HCLA++   +VY+WG+N  GQ G G  T  + +P  VS L    I  ++ G+SHS+AWTA   D
Sbjct:  373 EVYVWGSNSSHQLVEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTL-----KKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGEVSCGS--SHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRD 739

HSP 4 Score: 182.956 bits (463), Expect = 7.206e-44
Identity = 140/386 (36.27%), Postives = 218/386 (56.48%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKV--PVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXX-XXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV+ WG N   QL  VEG++ K+  P L    S    + I  G+   F++S DG V A G G+ GRLG+G + +  T   ++    + + KV+ + G   H LA    G V++WGD +  KLG             P L++  ++ +++  ++AG  HSAA++  GELYTWG+G +GRLGHG+ + +  P +V+ +   +V  V+CGS  + T+ ++K  D R       +VWS+G GD GKLG G  +    P  IE L+G  + KV  GSQ SL LT++G+VY WG G     G  S+    +P+ + +L   +I+DV+ G  HC+  + D EVY+WG+N  GQ G G +T   ++P+ +  L G  I +++ G++H+LAWT +
Sbjct:  373 EVYVWGSNSSHQL--VEGTQEKILQPKLAPSFS--DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHG----NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGEVSCGS--SHTIALSK--DGR-------TVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCG-SSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTAL 736

HSP 5 Score: 101.679 bits (252), Expect = 2.236e-19
Identity = 85/267 (31.84%), Postives = 133/267 (49.81%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGE-TFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALT 10219
            +++ WG  D  +LG   + + + P   EAL   + V +S G K    VT  GK++  G+   GRLG+G+ ++        P+R+ AL+ Y I +VA   G  H +A++ +G   +++G+GD GKLG  +    + P+KI    G  +  VACG+  S A+   GH+YT+G      L  G       P+ +  L    +  VA G+    TLAL S+  V++WG    G+LG G ++    P  +  +   NV QI  G   S A T
Sbjct: 4102 EVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKL-----PERVTALEGYQIGQVAC--GLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAE--HTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQGKNVRQISAGRCHSAAWT 4359

HSP 6 Score: 99.7525 bits (247), Expect = 8.046e-19
Identity = 96/358 (26.82%), Postives = 157/358 (43.85%), Query Frame = 2

Query: 12398 DAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEG---SKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSG-LEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHG-SDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT---EDGEVYSW 13447
            +A + C  + S  G  V + G    G+LG  +    S +K      H S  +     G +      + +G V++ G G+ G+LG G++ + + P L+ G L+ K+VV   V++G +H  A+  +G +Y WG+ +  +LG             PTLVK +               A       ++++G G  G+LGHG+ +    PK++EAL+G  +  V  GS             S + L     V++WG G     G       + P  IE L    ++ V  G    L L+   EVY WG     + G G S   + KP+KV+ L+   I  ++ G+ H +  T    D +V +W
Sbjct:  409 EAGQYCTFVISTDG-SVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVV--CVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG----DSNSRNIPTLVKDISNV-GEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGS------------QSSLALTSTGQVYAWGCGACLGCGSSEATALR-PKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAW 745

HSP 7 Score: 87.8113 bits (216), Expect = 3.529e-15
Identity = 56/193 (29.02%), Postives = 92/193 (47.67%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG-DIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTW--GSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW----LKYCTECNKSDDI 2197
            H  AVTE G++Y+WG    G+LG GD+  R  PT++   S     V +V+CG  H++ L++ G  ++S G    G+LGHGD    + P  I A  L G+ ++++      S+ L++ G ++ W  G+         +   PK+   +   R  I  + + DS    L     VY W    +  C + N +  I
Sbjct:  522 HSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS----NVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEA--LQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATR--IVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPI 706

HSP 8 Score: 86.2705 bits (212), Expect = 1.083e-14
Identity = 42/120 (35.00%), Postives = 74/120 (61.67%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAI 1996
             H +A+TE+G+V+SWG    GKLG G++  ++RP  I+       +V Q++CG +HS ++T  G +++ G    G+LG G+  ++ LP R+TA  L G  + Q+A   + ++ +S DG++
Sbjct: 4092 GHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQ--GEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTA--LEGYQIGQVACGLNHTLAVSADGSM 4207

HSP 9 Score: 81.6481 bits (200), Expect = 2.478e-13
Identity = 58/208 (27.88%), Postives = 106/208 (50.96%), Query Frame = 2

Query: 1409 NEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYS------SHVLAVTEAGQ-VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            + + R ++I     +  V   CG+ +    +SD  +  FTF +   ++    L N S  KL    RV  ++           +H LAV+  G  V+++G    GKLG G++  +  P  ID    C + +K+VACG + S+ LT+ G +Y+ G++ +  L  G  ++ + P +I    L GV+++ +AV    ++ L+++G ++ WGS
Sbjct: 4120 DRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKL--FTFGNG--DYGRLGLGNTSNKKL--PERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKIDVL--CGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPV--LAGVIIEDVAVGAEHTLALASNGDVYAWGS 4317

HSP 10 Score: 80.8777 bits (198), Expect = 5.132e-13
Identity = 59/202 (29.21%), Postives = 96/202 (47.52%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC---GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG-AIFTWGSTFDNCRRHLSN---WSPK-IETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSD--DIQPEL 2209
             H LA T  G+V+SWG    GKLG G++  +K P +I    +  LQ K V C   G  HS  +T+ G++Y+ G    G+LGHGD   R++P  +     +G    +++     ++ LS DG  ++++G   +    H      + PK IE     +   I ++     +   L  +G VY W    C  C  S+   ++P+L
Sbjct:  468 GHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLI----QGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVG----EVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMF---IRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKL 658

HSP 11 Score: 67.0106 bits (162), Expect = 6.790e-9
Identity = 39/117 (33.33%), Postives = 61/117 (52.14%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV----DGHQSMCLSNDGAIFTWG 2008
            VY WG    G+L +   ++   P    +FS    Q +QV CG+  + ++  +G + +CG    G+LG G+  D H+   I+A  L G +V Q+      DGH SM L+  G +F+WG
Sbjct: 3999 VYLWGAGRHGQLAEAG-RNVMVPAAAPSFS----QAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISA--LQGFVVTQLVTSCGSDGH-SMALTESGEVFSWG 4107

HSP 12 Score: 66.2402 bits (160), Expect = 1.220e-8
Identity = 45/132 (34.09%), Postives = 71/132 (53.79%), Query Frame = 2

Query: 1664 GQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEE-HSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPK 2056
            G V + G  + G+LGQG++ D    T+I       +     +CG + HS+ LT+SG+++S G    G+LGHG+   +  P +I A  L G  V Q++     S  +++DG +FT+G+  D  R  L N S K
Sbjct: 4046 GTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEA--LQGEEVVQMSCGFKHSAVVTSDGKLFTFGNG-DYGRLGLGNTSNK 4174

HSP 13 Score: 58.5362 bits (140), Expect = 2.857e-6
Identity = 61/264 (23.11%), Postives = 110/264 (41.67%), Query Frame = 2

Query: 1625 NIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG------------STFDNCRRHLSNWSPKIETCVNE-YRNEIDQIQVHDSTYSVLLKSGSVYTWLKY-CTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIKRNY 2368
            +I +     V+E  +VY WG+N+S +L +G  +   +P +  +FS      + +  G+  + +++  G + +CG+   G+LG GD  ++    ++T      I  +      DGH ++  + +G +F+WG            ST    +        K+  CV+  YR+            + + + G +YTW +         D     + T++K  + NV  +S G      L K G  RT  S    D+   G G   R Y
Sbjct:  359 SIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFS----DAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGH-TLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHS-----------AAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVK-DISNVGEVSCGSSHTIALSKDG--RTVWSFGGGDNGKLGHGDTNRVY 603

HSP 14 Score: 57.7658 bits (138), Expect = 3.894e-6
Identity = 35/103 (33.98%), Postives = 55/103 (53.40%), Query Frame = 2

Query: 1646 LAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV 1954
            +A+T+ G VY++G +    L +G  ++  RP  I   +   + ++ VA G EH+L L  +GD+Y+ G N  GQLG G       P  +T   L G  V+QI+ 
Sbjct: 4252 VALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLA--GVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTG--LQGKNVRQISA 4350

HSP 15 Score: 57.7658 bits (138), Expect = 4.720e-6
Identity = 47/159 (29.56%), Postives = 72/159 (45.28%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSM---CLSNDGAIFTW---------GSTFDNCRRHLSNWSPKIET 2065
            S   LA+T  GQVY+WG      LG G ++    RP +I+  +    ++  V+ G+ H L L+   ++Y+ G N MGQ G G+      PI      S L G+ ++QI+     S+    L  D  +  W          STF + R  L  +  KI +
Sbjct:  623 SQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAAT--RIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTG---PITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINS 774

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. UniProt/SwissProt
Match: sp|Q9FN03|UVR8_ARATH (Ultraviolet-B receptor UVR8 OS=Arabidopsis thaliana OX=3702 GN=UVR8 PE=1 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 4.538e-42
Identity = 115/348 (33.05%), Postives = 171/348 (49.14%), Query Frame = 2

Query: 9434 WGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTG-KVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSAL 10474
            WG  +  QLG         P    AL     VS++ G+      +++G +VY  G    GRLG G+ +D+       P  ++AL    I ++A   G  H +A+T  GE  SWG   +G+LG         P+KI+ F+G R+  VA G+ H+AA+   G LY WG G YG LG GD   RL PE V S    K+  VACG R   +++ +     + W        G       LIP K+E +S S + QI  G + + ALT +G+++ WG   + ++G G +     P+Q+      K+V ++ G  H LAVT+R  V++WG   +GQ G G       P ++ AL
Sbjct:   39 WGRGEDGQLGHGDAEDRPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFT-----PLPIKALHGIRIKQIAC--GDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDH--LIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEAL 377

HSP 2 Score: 155.606 bits (392), Expect = 1.975e-38
Identity = 99/303 (32.67%), Postives = 167/303 (55.12%), Query Frame = 2

Query: 9635 DITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGG-HLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG--TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            D+ A+ +  P R     K  I+     +G  H++AL       SWG G+DG+LGH        P ++    G ++V V CG+ H+ A    G  +Y+WG GD+GRLGHG+++    P  +K+L   ++ Q+ACG  D+  LA+T +  V SWG    G+LG G +   L+PQKI+      +  +  GA+ + A+TE+G ++ WG G Y  LG G  TD+ +  P ++      K+  +A G  H ++V+  G +Y++G + +GQ G+G +  ++ P  + AL ++ I+ ++ G  H++A T+
Sbjct:    4 DMAADEVTAPPR-----KVLIIS----AGASHSVALLSGDIVCSWGRGEDGQLGHGDAEDRPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACG--DSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLV--PERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTS 293

HSP 3 Score: 155.221 bits (391), Expect = 3.100e-38
Identity = 103/312 (33.01%), Postives = 163/312 (52.24%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNG-ETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
            G   +G+LG G   D  +     P +L ALD + IV V    G  H +A +++G E +SWG GD G+LGH +   L  P  IK   G R+  +ACG SH  A+   G + +WG    G+LG GDT   L P+ +++    ++  VA G+    T A+T D  ++ WG G +G LG G  +  L+P+++       +  + CG + + +++ +G ++T+G   Y +LGHG  +    P ++E L  + I  ++ G  H +A+T  G++Y WG N  GQ G G       P  V    D K+  V+CG  H++A
Sbjct:   40 GRGEDGQLGHGDAEDRPS-----PTQLSALDGHQIVSVTC--GADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGAE--HTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLA 342

HSP 4 Score: 139.813 bits (351), Expect = 4.223e-33
Identity = 107/358 (29.89%), Postives = 172/358 (48.04%), Query Frame = 2

Query: 9254 DTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVE---NQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDL 10318
            D VC+     W +    +L      +   PT  S       V      D++   S+   ++Y WG  D  +LG   +S +  P+  +AL  +    I+ G      VT  G+V   G + NG+LG+G   D        P++++A +   I  VA  +G  H  A+T++G+ + WG G  G LG   R     P ++    G+++  VACG  H+ ++ + G LYT+G   YG+LGHGD    L P  +++L +  + Q++ G R   T+ALTSD  ++ WG   FG++G G +     P ++       V+Q+ CG + + A+TE   V+ WG+G   +LG G       P  IE L
Sbjct:   34 DIVCS-----WGRGEDGQLGHGDAEDRPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLV-----PQKIQAFEGIRIKMVA--AGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWR--HTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEAL 377

HSP 5 Score: 136.346 bits (342), Expect = 6.170e-32
Identity = 116/368 (31.52%), Postives = 192/368 (52.17%), Query Frame = 2

Query: 12434 SGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII----GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLT 13525
            SG  V SWG    GQLG  +      P     LSAL   QI+    G + ++        VY+ G+G+ GRLG G++  + TP+ +  L    + ++A   G  HCLA+   G V +WG  ++ +LGL       ED L P  +++     I  +AAG  H+AA++  G+LY WG GRYG LG G+  D+  P+ V +  G  +  VACG     T+ ++           + +++++G   YG+LG G  +   +P K+E L  + + ++  G + ++ LT+ G++Y WG   + ++G G++     P +V   + +K++ V+CG  H +  TE   V++WG    GQLG G +   + P+IIE+L+
Sbjct:   32 SGDIVCSWGRGEDGQLGHGDAEDRPSPT---QLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIAC--GDSHCLAVTMEGEVQSWGRNQNGQLGLGDT----EDSLVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGW--RHTISVSY----------SGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEALS 378

HSP 6 Score: 125.946 bits (315), Expect = 1.989e-28
Identity = 93/290 (32.07%), Postives = 146/290 (50.34%), Query Frame = 2

Query: 12716 VNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXX-XXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTT 13582
            +++G  H +AL +  +V +WG  ED +LG        ED  +PT + +L   +I+ +        A      E+Y+WG G +GRLGHGN  D   P  ++AL G  +  +ACG  D+  L +T   +          V SWG    G+LG G  +   +P KI+  EG  +  V  G++ +  +T  G++Y WG G Y  LG G       PE+V     +K+  VACG  H I  +  G +Y++G +  GQLG G    +  P  +E+L+   I++++ G  HT+A T+
Sbjct:   20 ISAGASHSVALLSGDIVCSWGRGEDGQLGHG----DAEDRPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACG--DSHCLAVTMEGE----------VQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTS 293

HSP 7 Score: 116.701 bits (291), Expect = 2.704e-25
Identity = 105/350 (30.00%), Postives = 172/350 (49.14%), Query Frame = 2

Query: 12545 PRQII----GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGL-VYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            PR+++    G   S+ ++S D  V + G G +G+LG G  E   +P  +S L+   +V  +V  G  H +A   +G+ VY+WG  +  +LG         D+ TP  +K+L    I  IA G SH  A++  GE+ +WG+ + G+LG G+ +D   P+ ++A  G  +  VA G+    T  +T++ D           W WG      LG     +  +P ++ +  G  +  V CG + ++ ++ SG +YT+G   Y +LGHG       P K+  L+   I  ++ G  H +  T DG++Y WG N  GQ+G G       P  +     + + +V+CG  HTLA T
Sbjct:   14 PRKVLIISAGASHSVALLSGD-IVCSWGRGEDGQLGHGDAEDRPSPTQLSALDGHQIV--SVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHG----NSSDLFTPLPIKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGA--EHTAAVTEDGD--------LYGWGWGRYGNLGLGDRTDRL--VPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVT 344

HSP 8 Score: 108.612 bits (270), Expect = 1.233e-22
Identity = 97/324 (29.94%), Postives = 156/324 (48.15%), Query Frame = 2

Query: 12428 SASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACG 13399
            S SG+EV+SWG    G+LG    S +  P+  + L  +R +QI  G+     V+++G V + G   NG+LG+G TE    P  +    E I +K+ V +G +H  A+  +G +Y WG      LGL  R     D L P  V S    ++  +A G  H+ ++S SG LYT+G  +YG+LGHG+ +D   P  +EAL    +  ++ G     T+ +T   D ++        W W       +G         P+++   +   V++V CG + +L +T    V+ WG+G   +LG G       P+ +  L+    +D A G
Sbjct:   83 SQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAF-EGIRIKM-VAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRT----DRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGW--RHTMALTS--DGKL------YGWGWNKFGQVGVGNNLDQCS--PVQVRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEALS----VDGASG 384

HSP 9 Score: 89.3521 bits (220), Expect = 2.114e-16
Identity = 50/124 (40.32%), Postives = 73/124 (58.87%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            SH LAVT  G+V SWG N +G+LG GDT+D   P  I  F    +++K VA G EH+  +T+ GD+Y  G    G LG GD  DR +P R+T++   G  +  +A     ++ +S  GA++T+G
Sbjct:  130 SHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFE--GIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTG--GEKMSMVACGWRHTISVSYSGALYTYG 249

HSP 10 Score: 87.8113 bits (216), Expect = 5.854e-16
Identity = 45/126 (35.71%), Postives = 74/126 (58.73%), Query Frame = 2

Query: 1634 SSHVLAVTEAG-QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + H +A +++G +VYSWG    G+LG G++ D   P  I       +++KQ+ACG+ H L +T  G++ S GRN  GQLG GD +D  +P +I A +  G+ +K +A     +  ++ DG ++ WG
Sbjct:   76 ADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALH--GIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFE--GIRIKMVAAGAEHTAAVTEDGDLYGWG 197

HSP 11 Score: 83.5741 bits (205), Expect = 1.606e-14
Identity = 46/125 (36.80%), Postives = 70/125 (56.00%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + H  AVTE G +Y WG    G LG GD  DR  P  +   S    ++  VACG  H++ ++ SG +Y+ G +  GQLGHGD++D  +P ++ A  L    + QI+     +M L++DG ++ WG
Sbjct:  181 AEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERV--TSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEA--LSNSFISQISGGWRHTMALTSDGKLYGWG 301

HSP 12 Score: 79.337 bits (194), Expect = 3.694e-13
Identity = 45/126 (35.71%), Postives = 69/126 (54.76%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG-DIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +SH +A+     V SWG    G+LG GD +DR  PT +        Q+  V CG +H++  +QSG ++YS G    G+LGHG+  D   P+ I A  L G+ +KQIA      + ++ +G + +WG
Sbjct:   24 ASHSVALLSGDIVCSWGRGEDGQLGHGDAEDRPSPTQLSALD--GHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKA--LHGIRIKQIACGDSHCLAVTMEGEVQSWG 145

HSP 13 Score: 68.9366 bits (167), Expect = 7.222e-10
Identity = 47/190 (24.74%), Postives = 90/190 (47.37%), Query Frame = 2

Query: 1412 EKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTF-----------KHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQI 1948
            ++   +++  +G +   +  CGW + ++ S    + T+ +           + + I H+ + L N  + ++    R           H +A+T  G++Y WG N  G++G G+  D+  P  +  F     +V QV+CG  H+L +T+  ++++ GR   GQLG G+  DR+ P  I A  + G   + I
Sbjct:  211 DRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWR-----------HTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQV-RFPDDQ-KVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEALSVDGASGQHI 387

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. TrEMBL
Match: A0A3M6TI31 (Uncharacterized protein OS=Pocillopora damicornis OX=46731 GN=pdam_00014859 PE=4 SV=1)

HSP 1 Score: 1397.88 bits (3617), Expect = 0.000e+0
Identity = 842/1984 (42.44%), Postives = 1156/1984 (58.27%), Query Frame = 2

Query: 9359 TLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLV------SNLMARTCSQSTELTKKESDNLPSTAN----------------KRLSVMESF------------LLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLLL---VDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEI--ELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAIT--AVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ----------SVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSP-YADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            T +E+T E Q N          ++VWGLNDKDQLG    SK+K+P+L++ +S L    +SGGSKSLF V   GKV+  G+S+NGRLG+G    IT  V++ P+++E L ++ + KV+VHSGGRHA+A+T  G+ FSWGEG+DGKLGH +++  + P+ ++  K K V +++CGSSHSAA++  G LYTWGLG+YGRLGHGD   +L P+ V++L     + VACGSRDAQTLALT D  VWSWGDGDFGKLGRGGS GC +P  +E +    V ++ CGAQ S ALT+ GQVWTWGKGDY+RLGHG D HIR+P  +E LK  K+V +AVGALHCLAVT++G+V++WGDNDHGQQGNGT T N RP LV  L + KI  VACGSSHS+AW  SD  + +  +                     P++F  + DPLGA        NI  +      +T+++        +  +L+ ++  L     +   +  +   LQ++ +R+ V       + + R    S E   +E+ +L S +                  R S  E F             L  + LKL  A+ +++    +++L       +    ++  +LL   + E+E     NSS ++G                     +V+ES HPY ++T  SG V IP A  L VEFD+QCSTER  D L IMD    +V+ RSG+ W DW S++ ++G+EL W F SD S+  WGW+F V P+        +  D               P+I L++ LL  +  + Q    + +L     L+ ++  +       R WA+ ++  ++        ++    ID  ++        + +    +T N+  +  I +                          +  L   + +Q+++EEP V+  K LF+S F K L+  +C + LD +   +   EWAWFR +C+  R   SL   S LPY F+ E          V + +T  +   T   + EY D + F  +HD Q++ WL  RP  W   W     SG  ++ WGHNHRGQLGG+EG K+K P  CE LSA+RP QI+GGEQ+LF V+ +G+VYATG+G+ GRLG+G TE+V +  L+  L+  ++ KV+V+SGGKH +AL  +G VY+WG+ +D KLG   R         P ++++L    I+DIA GGSHSA I+ SGELYTWGKGRYGRLGHG+ DDQ  PK+VEALRG  VI VACGSGDAQTLC+T N+           VWSWGDGDYGKLGRGG D CK+PMK+E L  AGV KV+CGSQFS+ LT SG VYTWGKGDY+RLGHGSD+HVR+P++VA L  KK++ +A GSLHC+ CT+ GEVY+WGDNDEGQLGDG+T    RPR++ +L GK  NRVACGSAHT+AW+T     +        RL     P   N L++    +L NR +LLHH++EL CS++   DL  +            +D +R +L+PS KE+ FR +VQTTM   ++HGP I++NR+                           + R  G    G T     K+VFGQ   K+       S  G      PD   LP+RVWKVK IGESVDDCGGGYSESI E+CDELQNG LP  I +P        ++DCF+L+P  A   +   F FLG L+GIAIRT  PLSL +++ +W+ L+G SL   DL   DKD +  LM ++ ++    E +++P+S  +  G EV L+ +      +   NR  Y+   ++Y++HEFD     +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+GV+++  ++ WFWE +E  +N  RSLFLRFVWGRTRLPR +           VL KYSP D YLPE+YTCFFLLK+P YS + +L EKL YAIHFCKSID DDYARI L 
Sbjct: 2996 TTTESTPEGQVN----------MFVWGLNDKDQLGGLKGSKIKIPMLSDVMSALKVQQVSGGSKSLFAVNLEGKVFACGESTNGRLGLGP---ITGNVLV-PRQIEGLSQFVVKKVSVHSGGRHAMAITIEGKLFSWGEGEDGKLGHGNKMNFDRPQLVETLKTKSVQEISCGSSHSAAVLSTGELYTWGLGEYGRLGHGDYQTQLRPKQVRALSGIHAIDVACGSRDAQTLALTDDGCVWSWGDGDFGKLGRGGSEGCSVPHVVERLKGQGVCKVLCGAQFSLALTKPGQVWTWGKGDYFRLGHGNDSHIRKPQVVEGLKGHKVVDVAVGALHCLAVTEQGKVFAWGDNDHGQQGNGTTTVNRRPQLVQGLDEFKITRVACGSSHSMAWAESDFPAPVAHE---------------------PVMFPASRDPLGA-------SNIGPESQEQSNSTEAETNEYGEHRHRPSLAKIVLSLNSNYERQQALGHILTALQIIYSRDAVVRALLDPHSLIRGDPTSVEADDEEAVSLASVSEMSIDDIVLPEVVSGGVSRTSFTEEFGEFTTSLGHDDSRLLVELLKL--AVADRAGENGKEVLSGVLRALAETKPEIASMLLELCISELEDVATDNSSVHSGFQ------------------PVVQESSHPYIDDTNTSGVVKIPGAEGLRVEFDKQCSTERRHDPLTIMDSTGRVVSVRSGREWSDWSSELRMSGDELRWKFMSDSSVNGWGWKFTVYPIPPAAAPCDVLSDRALQ---------SRPSIDLVRCLLETLGGKAQIPRLAASLSACAQLNTLSAGQ-------RTWALHRLKKLL-------MSEVGPVIDVPALFGYNLMYDQPIVQMKNTGNQRMSAGIASSALGK--------------------LVRGLPDTLRRQYEYEEPLVRGGKHLFHSDFFKVLVAFACDLTLDFLPCCADGHEWAWFRRFCMASRVASSLELRSPLPYDFLTE----------VGEKITEMVLETTQDCIVEYNDHKVFKKEHDEQLLLWLNQRPSDWTVTW---GGSGT-IYGWGHNHRGQLGGIEGGKVKFPQPCEALSAIRPVQIVGGEQTLFAVTAEGKVYATGYGHGGRLGLGGTETVTSVRLIESLQHVVIKKVSVHSGGKHAMALSQDGDVYSWGEGDDGKLGHGNR----NSCDRPRVIEALRGKSIVDIACGGSHSACITTSGELYTWGKGRYGRLGHGDSDDQLLPKLVEALRGQRVIDVACGSGDAQTLCLTDND----------CVWSWGDGDYGKLGRGGSDGCKIPMKVEALMRAGVCKVECGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAALQNKKVVAIATGSLHCVACTDTGEVYTWGDNDEGQLGDGSTNAIQRPRLVTALQGKQTNRVACGSAHTIAWSTTKPANA-------GRLPKEV-PMEFNHLQHIPLGALRNRLMLLHHFSELVCSSIALFDLQPRLKEPIGQGTSVALDALRGVLIPSGKEAAFRKVVQTTMVRDRQHGPVIELNRIQIK------------------------KYRSKG----GLTGPDGSKSVFGQACSKM-------SNFG------PDSLYLPHRVWKVKFIGESVDDCGGGYSESIAEMCDELQNGSLPLLIVTPNGREESGANRDCFILNPDAATPVHLNMFKFLGVLIGIAIRTGSPLSLNLAEPVWQQLAGMSLRVTDLAEIDKDYVPGLMCIRDMEREAFEAMEMPFSTPSASGHEVQLHNKIK---CITLDNREEYVRLALHYRLHEFDLQVSAVRAGMARVVPVPLLSLFTGPELETMVCGSPDIPLDLLKSVVTYKGVEANAPLVRWFWETLESFSNAERSLFLRFVWGRTRLPRTI-----------VLDKYSPPDHYLPESYTCFFLLKMPRYSCQRVLCEKLKYAIHFCKSIDSDDYARIDLT 4783

HSP 2 Score: 279.256 bits (713), Expect = 1.772e-70
Identity = 159/350 (45.43%), Postives = 213/350 (60.86%), Query Frame = 2

Query: 9491 PILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEAL-DKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            P    +L E+    I    K    VT+TGKVY    ++ G+               GP  +E+L  K  I+K+A +   +H +AL++ GE +SWG GD GKLGH      + P  I    GK+V+ +ACGSSHSAA+   G LYTWG G+YGRLGHG +   L P LV  LR Y ++ VACGS DA +LA+  D TVWSWGDGD+GKLG GGS G   P+ I+ +    V+++ CG+Q S ALT +GQ+  WGKGD  RLGH T+ H+R P  IE     KI+   VG++HCLAVT+ G+VYSWG N+ GQ G+ + T    PTL+S+L   +I  VACG + S AW+++
Sbjct:  476 PTTLGSLVEIGIAQICCAEKCFLAVTKTGKVYTCLYTTEGQ---------------GPVLIESLAHKCEIIKIATNPECKHFMALSREGEVYSWGSGDGGKLGHGDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGYHIIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDGYKAPKVIDKLQSLGVVRVFCGSQFSVALTRDGQLLAWGKGDGSRLGHVTEDHVRYPKVIEAFCGKKIIDFGVGSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEITGVACGPAQSFAWSSA 810

HSP 3 Score: 256.914 bits (655), Expect = 8.169e-64
Identity = 169/384 (44.01%), Postives = 220/384 (57.29%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKI-VVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVL--TPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV  WG    G  G   G     P     L  +   QI   E+    V+  G+VY   +   G          Q P+L+  L  K  ++K+A N   KH +AL   G VY+WG  +  KLG       G++     PTL+  L   ++I IA G SHSAA++  GELYTWG+G YGRLGHG+ +D   P +V  LRGYH+I VACGSGDA +L +  +           +VWSWGDGDYGKLG GG D  K P  I+ L+  GV++V CGSQFS+ LT  G++  WGKGD  RLGH +++HVR P+ +     KKIID   GS+HC+  TEDGEVYSWG N++GQLGD + T  + P +I SL GK I  VACG A + AW++ 
Sbjct:  458 EVLGWGWLSWGNAGHTLG-----PTTLGSLVEIGIAQICCAEKCFLAVTKTGKVYTCLYTTEG----------QGPVLIESLAHKCEIIKIATNPECKHFMALSREGEVYSWGSGDGGKLGH------GDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGYHIIDVACGSGDAHSLAVADD----------GTVWSWGDGDYGKLGHGGSDGYKAPKVIDKLQSLGVVRVFCGSQFSVALTRDGQLLAWGKGDGSRLGHVTEDHVRYPKVIEAFCGKKIIDFGVGSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEITGVACGPAQSFAWSSA 810

HSP 4 Score: 124.02 bits (310), Expect = 1.367e-23
Identity = 76/268 (28.36%), Postives = 131/268 (48.88%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSK--IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSL--FCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +Y+W      KL    N+  ++PT  +    +  ++    S   + + S+  +Y WG  +  +LG  ++    +P+L   L     + ++ GS       V   G V+  GD   G+LG G      A     PK ++ L    +V+  V  G + ++ALT++G+  +WG+GD  +LGH +   + YP+ I+ F GK+++D   GS H  A+   G +Y+WG  + G+LG      +  P L+ SL   ++  VACG   AQ+ A +S
Sbjct:  551 VYSWGSGDGGKLGHGDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGYHIIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDGYKA-----PKVIDKLQSLGVVR--VFCGSQFSVALTRDGQLLAWGKGDGSRLGHVTEDHVRYPKVIEAFCGKKIIDFGVGSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEITGVACGP--AQSFAWSS 809

HSP 5 Score: 117.857 bits (294), Expect = 1.053e-21
Identity = 81/271 (29.89%), Postives = 131/271 (48.34%), Query Frame = 2

Query: 9266 NNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMS--KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGS--KSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +  +Y+W +    KL     ++ + P        ++ V+        + I +  ++Y WG     +LG   +    LP L EAL     + ++ GS      C+T    V+  GD   G+LG G            P ++EAL +  + K  V  G + ++ALTK+G  ++WG+GD  +LGH S   +  P+++   + K+VV +A GS H  A    G +YTWG  D G+LG G T     P LV +L+  +  +VACGS  A T+A ++
Sbjct: 4050 DGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALRGKSIVDIACGGSHSACITTSGELYTWGKGRYGRLGHGDSDDQLLPKLVEALRGQRVIDVACGSGDAQTLCLTDNDCVWSWGDGDYGKLGRGGSDGCKI-----PMKVEALMRAGVCK--VECGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAALQNKKVVAIATGSLHCVACTDTGEVYTWGDNDEGQLGDGSTNAIQRPRLVTALQGKQTNRVACGS--AHTIAWST 4311

HSP 6 Score: 98.5969 bits (244), Expect = 5.593e-16
Identity = 68/220 (30.91%), Postives = 105/220 (47.73%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG 2260
            H +A+++ G VYSWG    GKLG G+     RP +I+        +  +ACG  HS  +T SG++Y+ G+   G+LGHGD  D+ LP  + A  L G  V  +A      Q++CL+++  +++WG            D C+  +     K+E  +   R  + +++        L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G
Sbjct: 4043 HAMALSQDGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALR--GKSIVDIACGGSHSACITTSGELYTWGKGRYGRLGHGDSDDQLLPKLVEA--LRGQRVIDVACGSGDAQTLCLTDNDCVWSWGDGDYGKLGRGGSDGCKIPM-----KVEALM---RAGVCKVECGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAALQNKKVVAIATG 4250

HSP 7 Score: 97.0561 bits (240), Expect = 1.790e-15
Identity = 51/143 (35.66%), Postives = 80/143 (55.94%), Query Frame = 2

Query: 1589 LWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV---DGHQSMCLSNDGAIFTWG 2008
            L  K  +I +  N    H +A++  G+VYSWG+   GKLG GD      PT+I   +    QV Q+ACG  HS  +T  G++Y+ GR + G+LGHG  +D  +P+ +    L G  +  +A    D H S+ +++DG +++WG
Sbjct:  524 LAHKCEIIKIATNPECKHFMALSREGEVYSWGSGDGGKLGHGDNNFYDEPTLITGLA--GKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNG--LRGYHIIDVACGSGDAH-SLAVADDGTVWSWG 661

HSP 8 Score: 92.4337 bits (228), Expect = 3.895e-14
Identity = 63/203 (31.03%), Postives = 102/203 (50.25%), Query Frame = 2

Query: 9923 WGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGS--SHSVA 10525
            WG   +G  GH      L P  + SL +  + Q+ C  +    LA+T    V++      G+      S   +  K E + ++     EC  +   AL+  G+V++WG GD  +LGHG +    EP  I  L   +++ +A G+ H  AVT  G++Y+WG  ++G+ G+G+   ++ P LV+ L    I  VACGS  +HS+A
Sbjct:  462 WGWLSWGNAGH-----TLGPTTLGSLVEIGIAQICCAEK--CFLAVTKTGKVYTCLYTTEGQGPVLIES---LAHKCEIIKIAT--NPEC--KHFMALSREGEVYSWGSGDGGKLGHGDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGYHIIDVACGSGDAHSLA 650

HSP 9 Score: 85.8853 bits (211), Expect = 4.157e-12
Identity = 52/188 (27.66%), Postives = 93/188 (49.47%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK 2164
            V  V  +    H +A+T  G+++SWG    GKLG G+  +  RP +++T       V++++CG  HS  +  +G++Y+ G    G+LGHGD + +  P ++ A   I  +         Q++ L++DG +++WG   F    R  S     +   V   + +     +  + +S+ L K G V+TW K
Sbjct: 3094 VKKVSVHSGGRHAMAITIEGKLFSWGEGEDGKLGHGNKMNFDRPQLVETLKT--KSVQEISCGSSHSAAVLSTGELYTWGLGEYGRLGHGDYQTQLRPKQVRALSGIHAIDVACGSRDAQTLALTDDGCVWSWGDGDFGKLGRGGSEGC-SVPHVVERLKGQGVCKVLCGAQFSLALTKPGQVWTWGK 3278

HSP 10 Score: 79.337 bits (194), Expect = 3.720e-10
Identity = 53/170 (31.18%), Postives = 79/170 (46.47%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLG 9934
            ++ WG  D  +LG   +   K P + + L  L  V +  GS+    +TR G++   G     RLG      +T + +  PK +EA     I+   V  G  H +A+T++GE +SWG  + G+LG  S      P  I    GK +  VACG + S A    GH   W +G
Sbjct:  657 VWSWGDGDYGKLGHGGSDGYKAPKVIDKLQSLGVVRVFCGSQFSVALTRDGQLLAWGKGDGSRLG-----HVTEDHVRYPKVIEAFCGKKIIDFGV--GSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEITGVACGPAQSFAWSSAGH---WNVG 816

HSP 11 Score: 74.7146 bits (182), Expect = 9.253e-9
Identity = 42/127 (33.07%), Postives = 64/127 (50.39%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            SSH  AVT  G++Y+WG    G+LG G ++D   P +++     H  +  VAC  G+ HSL +   G ++S G    G+LGHG       P  I     +GV+  ++      S+ L+ DG +  WG
Sbjct:  591 SSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGYH--IIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDGYKAPKVIDKLQSLGVV--RVFCGSQFSVALTRDGQLLAWG 713

HSP 12 Score: 74.3294 bits (181), Expect = 1.189e-8
Identity = 42/134 (31.34%), Postives = 65/134 (48.51%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +IDV      +H LAV + G V+SWG    GKLG G +   K P +ID      L V +V CG + S+ LT+ G + + G+    +LGH  V + H+          G  +    V     + ++ DG +++WG
Sbjct:  636 IIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDGYKAPKVIDKLQ--SLGVVRVFCGSQFSVALTRDGQLLAWGKGDGSRLGH--VTEDHVRYPKVIEAFCGKKIIDFGVGSVHCLAVTEDGEVYSWG 765

HSP 13 Score: 72.4034 bits (176), Expect = 4.538e-8
Identity = 42/134 (31.34%), Postives = 67/134 (50.00%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
             IDV      +  LA+T+ G V+SWG    GKLG+G ++    P +++        V +V CG + SL LT+ G +++ G+    +LGHG+  D H+        L G  V  +AV     + ++  G +F WG
Sbjct: 3200 AIDVACGSRDAQTLALTDDGCVWSWGDGDFGKLGRGGSEGCSVPHVVERLK--GQGVCKVLCGAQFSLALTKPGQVWTWGKGDYFRLGHGN--DSHIRKPQVVEGLKGHKVVDVAVGALHCLAVTEQGKVFAWG 3329

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. TrEMBL
Match: A7SGI6 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g170394 PE=4 SV=1)

HSP 1 Score: 1382.85 bits (3578), Expect = 0.000e+0
Identity = 842/1958 (43.00%), Postives = 1150/1958 (58.73%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRN-------------LQVLVARNLVSNLMARTCSQSTELTKKESDNLPSTANKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLLLVDEIEKFGDSNS--------SKNNGIHHYCD---NKDFVTMMKRTRDISIV--------RESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSV----------MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQ----NGHLPFFISSP--------DKDCFVLSPYA-DKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            K++VWGLNDKDQLG    SK+K+P+L+E +  L    I+GGSK+LF V+  GKV+  G+S+NGRLG+G    ++A V + P+++E L  + + KV+VHSGGRHA+ALT  G+ FSWGEG+DGKLGH +R+  ++P+ I  FK   V D++CGSSHSAAI+  G LYTWGLG+YGRLGHGD    L P+ V+S   ++V+ +ACGSRDAQTLALT D TVWSWGDGDFGKLGRGGS GC +P  +E +    V ++ CGAQ S AL+ +G VWTWGKGDYYRLGHG D H+R+P  ++ L+  KIV +AVGALHCLAVTD GQV++WGDNDHGQQGN T T N RP LV+ L   KI  VACGSSHS+AW  SDL    P+ A +                  P++F  + DPLGA  +             + E TQS +    +  ++ +L   IS  R R +   ++ SL  N             LQ++ AR+ V   +  + +      K    + P+     L+ +    L    L +++    Q+V+  +DL   T      + R +  LL +    + G+           S   G     D         +   T D SIV        +ES HPY ++T  SG V +  A  L VEFDRQCSTER  D L IMD    I++ RSG+ W +W S++ ++G+EL W F SD S+  WGWRF V P+        +  D            LF P+I L++ LL+         S   +L  SL   A     L    R WA+ ++  ++R+ ++G                          P  D P       I       DEE++  S   +  +      +  L + + +Q+++EEP V+  K L +S F K ++ L+C + +D +       EWAWFR +C+  R   SL +   LPY F+ + + + L+       L  E        EY     F  + D Q++ WL  RP  W   W     SG  ++ WGHNHRGQLG +EG+K+K+P   E L+++RP QI+GGEQ+LF V+ +G+VYATG+G+ GRLG+G T++V +  ++  L+  +V KVAV+SGGKH +AL  +G VY+WG+ +D KLG   R         P ++++L    +IDI+ GGSHSA I+++ ELYTWGKGRYGRLGHG+ +DQ  PK+VEALRG  VI VACGSGDAQTLC+T ++           VWSWGDGDYGKLGRGG D CK+PMK+E+L G GV KV+CGSQFS+ LT SG VYTWGKGDY+RLGHG D+HVR+P++VA L  KK+I +A GSLHC+  T+ GEVY+WGDNDEGQLGDGTT   +RPR++ +L GK I+RVACGSAHT+AW+T      +    PD+       P   N L++    +  NR +LLH ++ELFC+++   DL+              +D +R +L+PS+KE+ FR +VQTTM   ++HGP I++NR+                           + R  G    G       K+VFGQ         D +S  G      P+   LP+RVWKVK IGESVDDCGGGYSESI E+CDELQ    NG LP  I +P        ++DCF+L+P A    +   F FLG L+GIAIRT  PLSL +++  WK L+G +L   DL   DKD +  LM ++ +D   LE + +P+S  +  G+E+ L+ +      +   NR  Y+   +N+++HEFD+ C  +R G+  V+P+P L+LF+  ELE +VCG+  IP+  LKS+  Y+G+  +  ++ WFW+ +E  +N  RSLFLRFVWGRTRLPR ++D RG++FV QVL KY+P D YLPE+YTCFFLLK+P YSS  IL EKL YA+HFCKSID DDYARI L 
Sbjct: 2422 KVFVWGLNDKDQLGGLKGSKIKVPVLSEFIGALKVQQIAGGSKTLFAVSHDGKVFACGESTNGRLGLGP---LSANVTV-PRQIENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSCVRDMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGNDTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVNGLEGQKITRVACGSSHSIAWAESDL----PTPATHE-----------------PVMFPVSRDPLGASCL-------------APEPTQSPSATILDTISNNDL---ISGKRHRPSLAKIVLSLNTNCERQQALGHILTALQIIYARDAVVGALMDSQAFLASDPKASPRDDPTDEAVSLASVPEVSLDDVTLTVESHASRQAVV--EDLDEFTAGLGPEDARLLVELLKLAVAGRAGEPGQDVLSRVLRSLAQGRPEIADMLLELCITELEDVTTDNSIVHSAFQPVVQESSHPYTDDTNTSGVVKVAGAEGLRVEFDRQCSTERRHDPLTIMDSTGRILSLRSGREWSEWASELRVSGDELRWKFTSDSSVNGWGWRFTVYPIAPAAAPCDVMSDRA---------LLFRPSIDLVRCLLDFQLETLCSPSQIPRLAASLGACA-QLSTLSASQRTWALHRLRKLLRS-DVG--------------------------PPLDVPTLLGYNLI-------DEEEMAISGSSLGSL------VRGLPEALQRQYEYEEPLVRGGKHLMHSDFFKVMVALACDLGIDLLPCCMDRHEWAWFRRFCMASRIASSLESRLPLPYNFVQDVREKILE-------LIPE--ECGDGEEYVSHTVFKREQDEQLLLWLNQRPSDWTMTW---GGSG-TIYGWGHNHRGQLGSLEGAKVKLPQTIEALASIRPVQIVGGEQTLFAVTAEGKVYATGYGHGGRLGLGGTDTVTSIKMLESLQHVVVRKVAVHSGGKHAMALSADGDVYSWGEGDDGKLGHGNR----NSCDRPRVIEALRGKGVIDISCGGSHSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEALRGNRVIDVACGSGDAQTLCLTDDD----------CVWSWGDGDYGKLGRGGSDGCKIPMKVESLIGLGVSKVECGSQFSVALTRSGAVYTWGKGDYYRLGHGVDDHVRRPKRVAALQGKKVITIATGSLHCVASTDTGEVYTWGDNDEGQLGDGTTNAIARPRLVTALQGKKISRVACGSAHTIAWSTC--KPVNAGRLPDE------VPMEYNHLQHIPLAATRNRLILLHEFSELFCTSVTLFDLDPGHEETLDYGPLVGLDTLRGVLIPSNKETAFRKVVQTTMVRDRQHGPVIELNRIQVK------------------------KYRSKG----GLAGPDGTKSVFGQ-------ACDKMSNFG------PESLFLPHRVWKVKFIGESVDDCGGGYSESIAEMCDELQASYHNGSLPLLIVTPNGREESGANRDCFILNPDATSAVHLGMFRFLGMLIGIAIRTGSPLSLNLAEPTWKQLAGMTLTVTDLAEIDKDYVPGLMCIRDMDAAALEAMDMPFSTPSASGREMRLHAKMK---TICQENREEYVRLALNHRLHEFDQQCSAVREGMGRVVPVPFLSLFTGPELETMVCGSPDIPLDLLKSVVTYKGIDGNAPLVRWFWDTLESFSNAERSLFLRFVWGRTRLPRTIADFRGRDFVFQVLDKYNPPDHYLPESYTCFFLLKMPRYSSHRILCEKLKYAVHFCKSIDSDDYARIDLT 4207

HSP 2 Score: 342.813 bits (878), Expect = 9.258e-90
Identity = 197/381 (51.71%), Postives = 261/381 (68.50%), Query Frame = 2

Query: 12440 LEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGS-TESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            ++V+ WG N + QLGG++GSKIKVPVL E + AL+ +QI GG ++LF VS DG+V+A G   NGRLG+G  + +V  P  +  L   +V KV+V+SGG+H +AL   G +++WG+ ED KLG   R+      L  T   S V+    D++ G SHSAAI  SGELYTWG G YGRLGHG+      PK V++   + VI +ACGS DAQTL +T +           +VWSWGDGD+GKLGRGG + C +P  +E L+G GV KV CG+QFSL L+ SG V+TWGKGDY+RLGHG+D HVRKP+ V  L  KKI+DVA G+LHC+  T+ G+V++WGDND GQ G+ TTT N RP+++  L G+ I RVACGS+H++AW 
Sbjct: 2421 IKVFVWGLNDKDQLGGLKGSKIKVPVLSEFIGALKVQQIAGGSKTLFAVSHDGKVFACGESTNGRLGLGPLSANVTVPRQIENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSCVR----DMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDD----------GTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGNDTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVNGLEGQKITRVACGSSHSIAWA 2787

HSP 3 Score: 283.878 bits (725), Expect = 5.641e-72
Identity = 150/293 (51.19%), Postives = 192/293 (65.53%), Query Frame = 2

Query: 9662 PKRLEALD-KYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            P  LE L  K  IV+V  H+ G+H +ALT+ GE +SWG GD GKLGH        P  +    GK+V+ ++CGS+HSAA+   G LYTWG G+YGRLGHG +  +L P LV  LR + ++ VACGS DA TLA   D TVWSWGDGD+GKLGRGGS GC  P+ IE +    V ++ CGAQ S ALT +G VWTWGKG+ +RLGHGT+ H+R P  +E L    +V ++VG++HCLA+TD G+VY WG ND GQ G+        PTLVS L    I  +ACG + S AW+ +
Sbjct:    5 PAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWSCA 297

HSP 4 Score: 256.144 bits (653), Expect = 1.629e-63
Identity = 155/307 (50.49%), Postives = 198/307 (64.50%), Query Frame = 2

Query: 12662 QTPILVSGLEEKI-VVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            Q P  +  L  K  +V+V  ++ GKH LAL   G VY+WG  +  KLG      P E+   PTLV  L   ++I I+ G +HSAA++  GELYTWG+G YGRLGHG+ +DQ  P +V  LRG+H+I VACGSGDA TL    +           +VWSWGDGDYGKLGRGG D CK P  IE L+G GV KV CG+QFSL LT  G V+TWGKG+ FRLGHG+++HVR P+ V  L+ K ++DV+ GS+HC+  T+ GEVY WG ND+GQLGD        P ++  L  KGI  +ACG A + AW+
Sbjct:    3 QPPAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHG-DTSPREE---PTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADD----------GTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWS 295

HSP 5 Score: 144.05 bits (362), Expect = 1.027e-29
Identity = 100/304 (32.89%), Postives = 157/304 (51.64%), Query Frame = 2

Query: 9512 SELDCVS---------ISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGS--SHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIR-EPMQIEDLKKTKIVHLAVGALHCLAVTDRGQ 10387
            +EL+C+S              K    +TR G+VY  G    G+LG G DT    E    P  +  L    +++++   G  H+ A+T  GE ++WG G+ G+LGH S      P  +   +G  ++DVACGS  +H+ A    G +++WG GDYG+LG G +    +P+ ++ L+   V +V CG++   +LALT D +VW+WG G+  +LG G       P+ +E +   +V+ +  G+    ALT+ G+V+ WG+ D  +LG   D  IR EP  +  L    IV +A G     A +  GQ
Sbjct:    6 AELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHG-DTSPREE----PTLVTGLAGKQVIRISC--GSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQ--FSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGD-IDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWSCAGQ 299

HSP 6 Score: 124.405 bits (311), Expect = 8.469e-24
Identity = 98/280 (35.00%), Postives = 147/280 (52.50%), Query Frame = 2

Query: 12569 QSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXE--LYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVR-KPEKVAQLNRKKIIDVACG 13399
            +    ++ +G VY+ G G+ G+LG G T   + P LV+GL  K V++++   G  H  A+ + G +Y WG     +LG        ED L P LV  L    IID+A G   +  ++ + +  +++WG G YG+LG G  D    PK +E L+G  V  V CG+    +L +T+          + SVW+WG G+  +LG G  D  + P  +E L+G  V+ V  GS   L LT +GEVY WG+ D  +LG   D  +R +P  V+ L  K I+ +ACG
Sbjct:   27 KHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISC--GSTHSAAVTSEGELYTWGRGNYGRLGHG----SSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGA--QFSLALTR----------DGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGD-IDCQIRPEPTLVSGLASKGIVGIACG 287

HSP 7 Score: 122.094 bits (305), Expect = 4.997e-23
Identity = 77/265 (29.06%), Postives = 128/265 (48.30%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSK--IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRT--GKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLA 10057
            +Y+W      KL     S  E+PT  +    +  +     S   + + S+  +Y WG  +  +LG  ++    +P+L   L     + ++ GS     +     G V+  GD   G+LG G      ++    PK +E L    + K  V+ G + ++ALT++G  ++WG+G+  +LGH +   + +P+ ++   GK VVDV+ GS H  A+   G +Y WG  D G+LG  D  +R  P LV  L    +V +ACG   AQ+ A
Sbjct:   38 VYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGG-----SDGCKNPKSIERLQGLGVCK--VYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGP--AQSFA 293

HSP 8 Score: 121.324 bits (303), Expect = 7.532e-23
Identity = 97/280 (34.64%), Postives = 138/280 (49.29%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            EV+SWG    G+LG  + S  + P L   L+  +  +I  G      V+ +G +Y  G GN GRLG GS+E    P+LVSGL    ++ VA  SG  H LA  ++G V++WGD +  KLG     + G D    P  ++ L    +  +  G   S A++R G ++TWGKG   RLGHG  D    PK+VEAL G HV+ V+ GS      C+         L     V+ WG  D G+LG     I   P  +  L   G++ + CG   S   + +G+
Sbjct:   37 EVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLG-----RGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGS----IHCLA--------LTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWSCAGQ 299

HSP 9 Score: 113.235 bits (282), Expect = 2.293e-20
Identity = 77/271 (28.41%), Postives = 129/271 (47.60%), Query Frame = 2

Query: 9266 NNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMS--KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGS--KSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +  +Y+W +    KL     ++ + P        +  ++        + I    ++Y WG     +LG   +    LP + EAL     + ++ GS      C+T    V+  GD   G+LG G            P ++E+L    + K  V  G + ++ALT++G  ++WG+GD  +LGH     +  P+++   +GK+V+ +A GS H  A    G +YTWG  D G+LG G T     P LV +L+  K+ +VACGS  A T+A ++
Sbjct: 3459 DGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALRGKGVIDISCGGSHSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEALRGNRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKI-----PMKVESLIGLGVSK--VECGSQFSVALTRSGAVYTWGKGDYYRLGHGVDDHVRRPKRVAALQGKKVITIATGSLHCVASTDTGEVYTWGDNDEGQLGDGTTNAIARPRLVTALQGKKISRVACGS--AHTIAWST 3720

HSP 10 Score: 99.7525 bits (247), Expect = 2.969e-16
Identity = 51/143 (35.66%), Postives = 84/143 (58.74%), Query Frame = 2

Query: 1589 LWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV---DGHQSMCLSNDGAIFTWG 2008
            L  K  ++ V  +    H LA+T  G+VYSWG+   GKLG GDT  R+ PT++   +    QV +++CG  HS  +T  G++Y+ GR + G+LGHG  +D+ +P+ +  S L G  +  +A    D H ++  ++DG +++WG
Sbjct:   11 LSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLA--GKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLV--SGLRGHHIIDVACGSGDAH-TLAAADDGTVWSWG 148

HSP 11 Score: 93.9745 bits (232), Expect = 1.328e-14
Identity = 46/136 (33.82%), Postives = 76/136 (55.88%), Query Frame = 2

Query: 10142 PQKIECMSLS-NVIQI--ECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD 10540
            P ++EC+S    ++Q+      +   ALT  G+V++WG GD  +LGHG      EP  +  L   +++ ++ G+ H  AVT  G++Y+WG  ++G+ G+G+    + P LVS L  + I  VACGS  +    A+D
Sbjct:    5 PAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAAD 140

HSP 12 Score: 92.8189 bits (229), Expect = 2.942e-14
Identity = 60/187 (32.09%), Postives = 98/187 (52.41%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWGS---------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSV-LLKSGSVYTWLK 2164
            H +A++  G VYSWG    GKLG G+     RP +I+        V  ++CG  HS  +TQ+ ++Y+ G+   G+LGHGD +D+ LP  + A  L G  V  +A      Q++CL++D  +++WG            D C+  +     K+E+ +    ++++      S +SV L +SG+VYTW K
Sbjct: 3452 HAMALSADGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALR--GKGVIDISCGGSHSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEA--LRGNRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPM-----KVESLIGLGVSKVEC----GSQFSVALTRSGAVYTWGK 3625

HSP 13 Score: 84.7297 bits (208), Expect = 8.950e-12
Identity = 42/124 (33.87%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTF-SRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H +A+T  G+++SWG    GKLG G+  +   P +IDTF S C   V+ ++CG  HS  +  SG++Y+ G    G+LGHGD      P ++ +     V+         Q++ L++DG +++WG
Sbjct: 2520 HAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSC---VRDMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVWSWG 2640

HSP 14 Score: 76.2554 bits (186), Expect = 3.245e-9
Identity = 47/136 (34.56%), Postives = 70/136 (51.47%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            NRVIDV      +  L +T+   V+SWG    GKLG+G +   K P  +++     L V +V CG + S+ LT+SG +Y+ G+    +LGHG       P R+ A  L G  V  IA      +  ++ G ++TWG
Sbjct: 3545 NRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPMKVESL--IGLGVSKVECGSQFSVALTRSGAVYTWGKGDYYRLGHGVDDHVRRPKRVAA--LQGKKVITIATGSLHCVASTDTGEVYTWG 3676

HSP 15 Score: 75.485 bits (184), Expect = 5.100e-9
Identity = 43/139 (30.94%), Postives = 73/139 (52.52%), Query Frame = 2

Query: 1592 WSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++ +RVID+      +  LA+T+ G V+SWG    GKLG+G ++    P  ++        V +VACG + SL L+ SG +++ G+    +LGHG+  D H+        L G  +  +AV     + +++ G +F WG
Sbjct: 2610 FTSHRVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQ--GQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGN--DTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWG 2744

HSP 16 Score: 72.4034 bits (176), Expect = 4.688e-8
Identity = 43/132 (32.58%), Postives = 69/132 (52.27%), Query Frame = 2

Query: 1619 DANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            D +  SSH  A+  +G++Y+WG    G+LG GD     +P  + +F+  H +V  +ACG  +  +L LT  G ++S G    G+LG G  +   +P  +    L G  V ++A     S+ LS  G ++TWG
Sbjct: 2565 DMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTS-H-RVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPV--EKLQGQGVCKVACGAQFSLALSTSGLVWTWG 2692

HSP 17 Score: 72.0182 bits (175), Expect = 7.245e-8
Identity = 41/127 (32.28%), Postives = 65/127 (51.18%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S+H  AVT  G++Y+WG    G+LG G ++D+  P ++      H  +  VAC  G+ H+L     G ++S G    G+LG G       P  I    L G+ V ++      S+ L+ DG+++TWG
Sbjct:   78 STHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHH--IIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSI--ERLQGLGVCKVYCGAQFSLALTRDGSVWTWG 200

HSP 18 Score: 66.6254 bits (161), Expect = 2.520e-6
Identity = 47/134 (35.07%), Postives = 68/134 (50.75%), Query Frame = 2

Query: 5567 LLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG--PNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKK 5962
            L+L++GVLGL QT++R     + G      ++      ++ + +  K   T       L    +A    LK GT V+RG DWK+GDQDG  P+   I+     +G  RVQW     T SYR GK+  YDL+L +
Sbjct: 1273 LVLSSGVLGLTQTIMRLAGPCDTGE-----EEDAALAAIIDEGKAAKKRPTV-----PLTGPEVA--KMLKIGTRVVRGPDWKWGDQDGPPPSEGRIIGELGEDGWARVQW-ETGSTNSYRMGKEGKYDLKLAR 1393

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. TrEMBL
Match: A0A2B4RK68 (E3 ubiquitin-protein ligase HERC2 OS=Stylophora pistillata OX=50429 GN=HERC2 PE=4 SV=1)

HSP 1 Score: 1381.31 bits (3574), Expect = 0.000e+0
Identity = 835/1989 (41.98%), Postives = 1145/1989 (57.57%), Query Frame = 2

Query: 9359 TLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLV------SNLMARTCSQSTELTKKESDNLPSTAN----------------KRLSVMES--------------FLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLL---------LLVDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLN-EIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ----------SVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            T +E+T E Q N          ++VWGLNDKDQLG    SK +     + +  +D V + G            +V+  G+S+NGRLG+G    IT  V++ P+++E L ++ + KV+VHSGGRHA+A+T  G+ FSWGEG+DGKLGH +++  + P+ ++  K K V +++CGSSHSAA++  G LYTWGLG+YGRLGHGD  M+L P+ V++L   + V VACGSRDAQTLALT D  VWSWGDGDFGKLGRGGS GC +P  +E +    V ++ CGAQ S ALT+ GQVWTWGKGDY+RLGHG D HIR+P  +E LK  K+V +AVGALHCLAVT++G+V++WGDNDHGQQGNGT T N RP LV  L + KI  VACGSSHS+AW  SD  + +  +                     P++F  + DPLGA        NI  +      + ++++       +  +L+ ++  L     +   +  +   LQ++ +R+ V         + R  + S E   +E+ +L S +                  R S +E                L+    L + +         L  +LR     +  +  ++ L+         L + E+E     NSS ++G                     +++ES HPY ++T  +G V IP A  L VEFD+QCSTER  D L IMD    +V+ RSG+ W DW S++ ++G+EL W F SD S+  WGWRF V P+        +  D               P+I L++ LL+ ++E   E   +  +L  SLS  A     L    R WA+ ++  ++        ++    ID  ++        + +    +T N+     I +                          +  L   + +Q+++EEP V+  K LF+S F K L+  +C + LD +   +   EWAWFR +C+  R   SL + S LPY F+ E + +  +       +  E    T   EY D + F  +HD Q++ WL  RP  W   W     SG  ++ WGHNHRGQLGG+EG K+K P  CE LSA+RP QI+GGEQ+LF V+ +G+VYATG+G+ GRLG+G TE+V +  L+  L+   + K+AV+SGGKH + L   G VY+WG+ +D KLG   R         P ++++L    I+DI+ GGSHSA I+ +GELYTWGKGRYGRLGHG+ DDQ  PK+VEALRG  VI VACGSGDAQTLC+T N+           VWSWGDGDYGKLGRGG D CK+PMK+E L  AGV KVDCGSQFS+ LT SG VYTWGKGDY+RLGHGSD+HVR+P++VA L  KK++ +A GSLHC+ CT+ GEVY+WGDNDEGQLGDG+T    RPR++ +L GK  NRVACGSAHT+AW+T     +        RL     P   N L++    SL NR +LLHH++EL CS++   DL  +            +D +R +L+PS KE+ FR +VQTTM   ++HGP I++NR+                           + R  G    G T     K+VFGQ   K+       S  G      PD   LP+RVWKVK IGESVDDCGGGYSESI E+CDELQNG LP  I +P        ++DCF+L+P A  + +   F FLG L+GIAIRT  PLSL +++ +W+ L+G SL   DL   DKD +  LM ++ ++    E +++P+S  +  G E  L+ +      +   NR  Y+   ++Y++HEFD     +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+GV ++  ++ WFWE +E  +N  RSLFLRFVWGRTRLPR + D RG++FV QVL KYSP D YLPE+YTCFFLLK+P YS + +L EKL YAIHFCKSID DDYARI L 
Sbjct: 2939 TTTESTPEGQVN----------VFVWGLNDKDQLGGLKGSKAE-----QIMKCIDWVVVEG------------RVFACGESTNGRLGLGP---ITGNVLV-PRQIEGLSQFVVKKVSVHSGGRHAMAITIEGKLFSWGEGEDGKLGHGNKMNFDRPQLVETLKTKSVQEISCGSSHSAAVLSTGELYTWGLGEYGRLGHGDNQMQLRPKQVRALSGSRAVDVACGSRDAQTLALTDDGCVWSWGDGDFGKLGRGGSEGCSVPHMVERLKGQGVCKVLCGAQFSLALTKLGQVWTWGKGDYFRLGHGNDSHIRKPQVVEGLKGHKVVDVAVGALHCLAVTEKGKVFAWGDNDHGQQGNGTTTVNRRPQLVQGLEEFKITRVACGSSHSMAWAESDFPAPVAHE---------------------PVMFPASRDPLGA-------SNIGPESQEQSISAEAESNEYGEHRHRPSLAKIVLSLNSNYERQQALGHILTALQIIYSRDAVIRALLDPRSLIRGNTTSVEAEDEEAVSLASVSEVSIDDVALPEAASGSVSRTSFIEDIGEFTSSLGHDDSRLLVELLKLAVADRAGENGKEVLSGVLRVLAQTKPEDANEMMLMISIASTLLELCISELEDVATDNSSVHSGFQ------------------PVLQESSHPYTDDTNTTGVVKIPGAEGLRVEFDKQCSTERRHDPLTIMDSTGRVVSVRSGREWSDWSSELRMSGDELRWKFMSDSSVNGWGWRFTVYPIPPAAAPCDVLSDRALQ---------SRPSIDLVRCLLDFKLETLGEKAQIP-RLAASLSACAQLN-TLSAGQRTWALHRLRRLLT-------SEVGPVIDVPALFGYNLMYDQPIVQMKNTGNQRMGAGIASSALGK--------------------LVRGLPDTLRRQYEYEEPLVRGGKHLFHSDFFKVLVAFACDLALDFLPCCADGHEWAWFRRFCMASRVASSLESRSPLPYDFLTEVREKITE-------MVLETQDCTV--EYHDHKVFKKEHDEQLLLWLNQRPSDWTVTW---GGSGT-IYGWGHNHRGQLGGIEGGKVKFPQPCEALSAIRPVQIVGGEQTLFAVTAEGKVYATGYGHGGRLGLGGTETVTSVRLIESLQHVAIKKIAVHSGGKHAMVLSLEGDVYSWGEGDDGKLGHGNR----NSCDRPRVIEALRGKSIVDISCGGSHSACITTTGELYTWGKGRYGRLGHGDSDDQLLPKLVEALRGQRVIDVACGSGDAQTLCLTDND----------CVWSWGDGDYGKLGRGGSDGCKIPMKVEALMRAGVCKVDCGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAALQNKKVVAIATGSLHCVACTDTGEVYTWGDNDEGQLGDGSTNAIQRPRLVTALQGKQTNRVACGSAHTIAWSTTKPANA-------GRLPKEV-PMEFNHLQHIPLGSLRNRLMLLHHFSELVCSSIALFDLQPRLKEPMGQGTSVALDALRGVLIPSGKEAAFRKVVQTTMVRDRQHGPVIELNRIQIK------------------------KYRSKG----GLTGPDGSKSVFGQACSKM-------SNFG------PDSLFLPHRVWKVKFIGESVDDCGGGYSESIAEMCDELQNGSLPLLIVTPNGREESGANRDCFILNPDATTSVHLNMFKFLGVLIGIAIRTGSPLSLNLAEPVWQQLAGMSLRVTDLAEIDKDYVPGLMCIRDMEREAFEAMEMPFSTPSASGHEAQLHNKIK---CITLDNREEYVRLALHYRLHEFDLQVAAVRAGMARVVPVPLLSLFTGPELETMVCGSPDIPLDLLKSVVTYKGVDANAPLVRWFWETLESFSNAERSLFLRFVWGRTRLPRTIVDFRGRDFVFQVLDKYSPPDHYLPESYTCFFLLKMPRYSCQRVLCEKLKYAIHFCKSIDSDDYARIDLT 4733

HSP 2 Score: 279.256 bits (713), Expect = 1.636e-70
Identity = 159/350 (45.43%), Postives = 214/350 (61.14%), Query Frame = 2

Query: 9491 PILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEAL-DKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            P    +L E+    I    K    VT+TGKVY    ++ G+               GP  +E+L  K  I+KVA +   +H +AL++ GE +SWG GD GKLGH      + P  I    GK+V+ +ACGSSHSAA+   G LYTWG G+YGRLGHG +   L P LV  LR + ++ VACGS DA +LA+  D TVWSWGDGD+GKLG GGS     P+ I+ +    V++I CG+Q S ALT +GQ+  WGKGD  RLGH ++ H+R P  IE     KI+  AVG++HCLAVT+ G+VYSWG N+ GQ G+ + T    PTL+S+L   +I+ VACG + S AW+++
Sbjct:  419 PTTLGSLVEIGIAHICCAEKCFLAVTKTGKVYTCLYTTEGQ---------------GPVLIESLAQKCEIIKVATNPECKHFMALSREGEVYSWGSGDGGKLGHGDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGFHIIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDSYKAPKVIDRLQSLGVMRIFCGSQFSVALTRDGQLLAWGKGDGSRLGHVSEDHVRYPKVIEAFCGKKIIDFAVGSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEISGVACGPAQSFAWSSA 753

HSP 3 Score: 257.299 bits (656), Expect = 7.806e-64
Identity = 169/384 (44.01%), Postives = 222/384 (57.81%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKI-VVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVL--TPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            EV  WG    G  G   G     P     L  +    I   E+    V+  G+VY   +   G          Q P+L+  L +K  ++KVA N   KH +AL   G VY+WG  +  KLG       G++     PTL+  L   ++I IA G SHSAA++  GELYTWG+G YGRLGHG+ +D   P +V  LRG+H+I VACGSGDA +L +  +           +VWSWGDGDYGKLG GG D  K P  I+ L+  GV+++ CGSQFS+ LT  G++  WGKGD  RLGH S++HVR P+ +     KKIID A GS+HC+  TEDGEVYSWG N++GQLGD + T  + P +I SL GK I+ VACG A + AW++ 
Sbjct:  401 EVLGWGWLSWGNAGHTLG-----PTTLGSLVEIGIAHICCAEKCFLAVTKTGKVYTCLYTTEG----------QGPVLIESLAQKCEIIKVATNPECKHFMALSREGEVYSWGSGDGGKLGH------GDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGFHIIDVACGSGDAHSLAVADD----------GTVWSWGDGDYGKLGHGGSDSYKAPKVIDRLQSLGVMRIFCGSQFSVALTRDGQLLAWGKGDGSRLGHVSEDHVRYPKVIEAFCGKKIIDFAVGSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEISGVACGPAQSFAWSSA 753

HSP 4 Score: 124.405 bits (311), Expect = 9.057e-24
Identity = 76/268 (28.36%), Postives = 132/268 (49.25%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSK--IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSL--FCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +Y+W      KL    N+  ++PT  +    +  ++    S   + + S+  +Y WG  +  +LG  ++    +P+L   L     + ++ GS       V   G V+  GD   G+LG G      A     PK ++ L    +++  +  G + ++ALT++G+  +WG+GD  +LGH S   + YP+ I+ F GK+++D A GS H  A+   G +Y+WG  + G+LG      +  P L+ SL   ++  VACG   AQ+ A +S
Sbjct:  494 VYSWGSGDGGKLGHGDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGFHIIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDSYKA-----PKVIDRLQSLGVMR--IFCGSQFSVALTRDGQLLAWGKGDGSRLGHVSEDHVRYPKVIEAFCGKKIIDFAVGSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEISGVACGP--AQSFAWSS 752

HSP 5 Score: 117.087 bits (292), Expect = 1.458e-21
Identity = 81/268 (30.22%), Postives = 130/268 (48.51%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMS--KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGS--KSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +Y+W +    KL     ++ + P        ++ V+        + I +  ++Y WG     +LG   +    LP L EAL     + ++ GS      C+T    V+  GD   G+LG G            P ++EAL +  + K  V  G + ++ALTK+G  ++WG+GD  +LGH S   +  P+++   + K+VV +A GS H  A    G +YTWG  D G+LG G T     P LV +L+  +  +VACGS  A T+A ++
Sbjct: 3992 VYSWGEGDDGKLGHGNRNSCDRPRVIEALRGKSIVDISCGGSHSACITTTGELYTWGKGRYGRLGHGDSDDQLLPKLVEALRGQRVIDVACGSGDAQTLCLTDNDCVWSWGDGDYGKLGRGGSDGCKI-----PMKVEALMRAGVCK--VDCGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAALQNKKVVAIATGSLHCVACTDTGEVYTWGDNDEGQLGDGSTNAIQRPRLVTALQGKQTNRVACGS--AHTIAWST 4250

HSP 6 Score: 98.2117 bits (243), Expect = 7.303e-16
Identity = 52/143 (36.36%), Postives = 80/143 (55.94%), Query Frame = 2

Query: 1589 LWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV---DGHQSMCLSNDGAIFTWG 2008
            L  K  +I V  N    H +A++  G+VYSWG+   GKLG GD      PT+I   +    QV Q+ACG  HS  +T  G++Y+ GR + G+LGHG  +D  +P+ +    L G  +  +A    D H S+ +++DG +++WG
Sbjct:  467 LAQKCEIIKVATNPECKHFMALSREGEVYSWGSGDGGKLGHGDNNFYDEPTLITGLA--GKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNG--LRGFHIIDVACGSGDAH-SLAVADDGTVWSWG 604

HSP 7 Score: 92.4337 bits (228), Expect = 3.859e-14
Identity = 68/221 (30.77%), Postives = 105/221 (47.51%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG 2260
            H + ++  G VYSWG    GKLG G+     RP +I+        +  ++CG  HS  +T +G++Y+ G+   G+LGHGD  D+ LP  + A  L G  V  +A      Q++CL+++  +++WG            D C+  +     K+E  +     ++D      S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G
Sbjct: 3982 HAMVLSLEGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALR--GKSIVDISCGGSHSACITTTGELYTWGKGRYGRLGHGDSDDQLLPKLVEA--LRGQRVIDVACGSGDAQTLCLTDNDCVWSWGDGDYGKLGRGGSDGCKIPM-----KVEALMRAGVCKVD----CGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAALQNKKVVAIATG 4189

HSP 8 Score: 92.0485 bits (227), Expect = 5.815e-14
Identity = 63/203 (31.03%), Postives = 102/203 (50.25%), Query Frame = 2

Query: 9923 WGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGS--SHSVA 10525
            WG   +G  GH      L P  + SL +  +  + C  +    LA+T    V++      G+      S   + QK E + ++     EC  +   AL+  G+V++WG GD  +LGHG +    EP  I  L   +++ +A G+ H  AVT  G++Y+WG  ++G+ G+G+   ++ P LV+ L    I  VACGS  +HS+A
Sbjct:  405 WGWLSWGNAGH-----TLGPTTLGSLVEIGIAHICCAEK--CFLAVTKTGKVYTCLYTTEGQGPVLIES---LAQKCEIIKVAT--NPEC--KHFMALSREGEVYSWGSGDGGKLGHGDNNFYDEPTLITGLAGKQVIQIACGSSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGFHIIDVACGSGDAHSLA 593

HSP 9 Score: 82.0333 bits (201), Expect = 5.946e-11
Identity = 42/136 (30.88%), Postives = 75/136 (55.15%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG 2008
            V  V  +    H +A+T  G+++SWG    GKLG G+  +  RP +++T       V++++CG  HS  +  +G++Y+ G    G+LGHGD + +  P ++ A  L G     +A      Q++ L++DG +++WG
Sbjct: 3020 VKKVSVHSGGRHAMAITIEGKLFSWGEGEDGKLGHGNKMNFDRPQLVETLKT--KSVQEISCGSSHSAAVLSTGELYTWGLGEYGRLGHGDNQMQLRPKQVRA--LSGSRAVDVACGSRDAQTLALTDDGCVWSWG 3151

HSP 10 Score: 78.5666 bits (192), Expect = 7.509e-10
Identity = 53/170 (31.18%), Postives = 80/170 (47.06%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLG 9934
            ++ WG  D  +LG   +   K P + + L  L  + I  GS+    +TR G++   G     RLG      ++ + +  PK +EA     I+  AV  G  H +A+T++GE +SWG  + G+LG  S      P  I    GK +  VACG + S A    GH   W +G
Sbjct:  600 VWSWGDGDYGKLGHGGSDSYKAPKVIDRLQSLGVMRIFCGSQFSVALTRDGQLLAWGKGDGSRLG-----HVSEDHVRYPKVIEAFCGKKIIDFAV--GSVHCLAVTEDGEVYSWGWNEQGQLGDTSCTNKAEPTLISSLAGKEISGVACGPAQSFAWSSAGH---WNVG 759

HSP 11 Score: 77.0258 bits (188), Expect = 1.901e-9
Identity = 51/178 (28.65%), Postives = 81/178 (45.51%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEY-RNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            SSH  AVT  G++Y+WG    G+LG G ++D   P +++     H  +  VAC  G+ HSL +   G ++S G    G+LGHG       P  I     +GV+  +I      S+ L+ DG +  WG    +   H+S    +    +  +   +I    V       + + G VY+W
Sbjct:  534 SSHSAAVTSEGELYTWGRGNYGRLGHGSSEDHLVPVLVNGLRGFH--IIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDSYKAPKVIDRLQSLGVM--RIFCGSQFSVALTRDGQLLAWGKGDGSRLGHVSEDHVRYPKVIEAFCGKKIIDFAVGSVHCLAVTEDGEVYSW 707

HSP 12 Score: 75.8702 bits (185), Expect = 4.246e-9
Identity = 42/134 (31.34%), Postives = 66/134 (49.25%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +IDV      +H LAV + G V+SWG    GKLG G +   K P +ID      L V ++ CG + S+ LT+ G + + G+    +LGH  V + H+          G  +   AV     + ++ DG +++WG
Sbjct:  579 IIDVACGSGDAHSLAVADDGTVWSWGDGDYGKLGHGGSDSYKAPKVIDRLQ--SLGVMRIFCGSQFSVALTRDGQLLAWGKGDGSRLGH--VSEDHVRYPKVIEAFCGKKIIDFAVGSVHCLAVTEDGEVYSWG 708

HSP 13 Score: 73.9442 bits (180), Expect = 1.661e-8
Identity = 43/142 (30.28%), Postives = 72/142 (50.70%), Query Frame = 2

Query: 1583 LKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++  S +R +DV      +  LA+T+ G V+SWG    GKLG+G ++    P +++        V +V CG + SL LT+ G +++ G+    +LGHG+  D H+        L G  V  +AV     + ++  G +F WG
Sbjct: 3118 VRALSGSRAVDVACGSRDAQTLALTDDGCVWSWGDGDFGKLGRGGSEGCSVPHMVERLK--GQGVCKVLCGAQFSLALTKLGQVWTWGKGDYFRLGHGN--DSHIRKPQVVEGLKGHKVVDVAVGALHCLAVTEKGKVFAWG 3255

HSP 14 Score: 72.4034 bits (176), Expect = 4.611e-8
Identity = 43/138 (31.16%), Postives = 72/138 (52.17%), Query Frame = 2

Query:  485 LGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTDTLPFWSGVTEQTYQFLKNTVLCPSSNDMIIPKPI-------RDAALVLLLEMGLIYGNLSMQLKHIIMLIQL-SSGSKN 874
            L  + A++ +   F F++R WR G E D+  C E++  A+E +Q +P A  F   D     P W  V E+  +FL++ V    + D +  KP+       +  AL +LLE+G+  G L   L+ I+++++L  SG  N
Sbjct:  223 LARIGARAALSFAFAFLRRAWRSGEEADL--CRELLDEALEALQCLPEATLF---DEASVSPVWLEVVERATKFLRSVVAGKGNEDRVYCKPLDSVPVSDQHVALGILLELGVQRGTLQHMLEVILLMLELWDSGQDN 355

HSP 15 Score: 72.4034 bits (176), Expect = 5.142e-8
Identity = 41/133 (30.83%), Postives = 70/133 (52.63%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            VD +   SH   +T  G++Y+WG    G+LG GD+ D+  P +++       +V  VAC  G+  +L LT +  ++S G    G+LG G      +P+++ A  L+   V ++      S+ L+  GA++TWG
Sbjct: 4026 VDISCGGSHSACITTTGELYTWGKGRYGRLGHGDSDDQLLPKLVEALR--GQRVIDVACGSGDAQTLCLTDNDCVWSWGDGDYGKLGRGGSDGCKIPMKVEA--LMRAGVCKVDCGSQFSVALTKSGAVYTWG 4154

HSP 16 Score: 72.4034 bits (176), Expect = 5.544e-8
Identity = 45/136 (33.09%), Postives = 67/136 (49.26%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
             RVIDV      +  L +T+   V+SWG    GKLG+G +   K P  ++   R    V +V CG + S+ LT+SG +Y+ G+    +LGHG       P R+ A  L    V  IA      +  ++ G ++TWG
Sbjct: 4075 QRVIDVACGSGDAQTLCLTDNDCVWSWGDGDYGKLGRGGSDGCKIPMKVEALMRAG--VCKVDCGSQFSVALTKSGAVYTWGKGDYYRLGHGSDDHVRRPKRVAA--LQNKKVVAIATGSLHCVACTDTGEVYTWG 4206

HSP 17 Score: 65.855 bits (159), Expect = 5.173e-6
Identity = 41/127 (32.28%), Postives = 63/127 (49.61%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            SSH  AV   G++Y+WG    G+LG GD + + RP  +   S    +   VACG  +  +L LT  G ++S G    G+LG G  +   +P  +    L G  V ++      S+ L+  G ++TWG
Sbjct: 3081 SSHSAAVLSTGELYTWGLGEYGRLGHGDNQMQLRPKQVRALSGS--RAVDVACGSRDAQTLALTDDGCVWSWGDGDFGKLGRGGSEGCSVPHMV--ERLKGQGVCKVLCGAQFSLALTKLGQVWTWG 3203

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. TrEMBL
Match: A0A162DDE6 (E3 ubiquitin-protein ligase HERC2 OS=Daphnia magna OX=35525 GN=APZ42_025304 PE=4 SV=1)

HSP 1 Score: 1360.13 bits (3519), Expect = 0.000e+0
Identity = 851/1978 (43.02%), Postives = 1182/1978 (59.76%), Query Frame = 2

Query: 9383 NQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTCSQSTELTKKESDNLPSTANKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFN---------------------QSNNLRQVGLLLLVDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEI------ELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICG----FLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTAD--EWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL----NRQ---SVM-----------DKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADK-TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETE----LENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIA 15124
            NQ  S   S    ++YVWGLNDK+QLG    SK+K+P   + +  L  ++++GGSKSLF VT++GK Y  G+ SNGRLG+G   +I       P ++ AL +Y + K+AVHSGGRHA+ALT +G  FSWGEGDDGKLGH     L+ PR ++   G R+ DVA GS+HSAA+   G LYTWGLG+YGRLGHGD   +L P+ V +L   +V+QV+CGSRDAQTLAL     V+SWGDGDFGKLGRGGS GC  P  ++ +S   V  +ECGAQ S ALT NG V+TWGKGDY+RLGHG+D+H+R P  +E L+  K++ ++VGALHCLAVTD GQV++WGDNDHGQQGNG+VT N RPTLV  +   KI  VACGSSHSVAWTA +  S  P +                     P+ F    DPLG+      + +    R+ +  T ++         +  ++          A Q  + C L+ ++Q+ + R+ V  + ++  + + +L  +     P+ +    +  E  +  FD +KL   + ++    L +LL+    N                     + +++R++ +   V E+E+     S +  GIHH+ +   F   +   +   IV+ES HPY ++  L+G V++P A  L VEFDRQCSTE+  D L + D    I+A RSG+ W DW  +V + GNEL W F SDGS+  WGWRF V P+         +  +       E L L  P++ ++  LL+ +      +       L  +L  +L+  A     L  + R+WA++++  I+                               TP   T + P + + EA E ++    V  SS +++  DI  G     L  L +++L+Q+++EE  V+  +QL +S F + LI L+C +R D + P+ T D   W+WFR YC   R    L+  + LP  F  + K +  +       +  +   ITA  ++ +P  FS++HD Q++ W+ S P+ W + W   +  G +++ WGHNHRGQLGGVEG+K+K+P +CE LSALRP Q+ GGEQ+LF V+ DGRVYATG+G  GRLGIG  ESV  P L+  L+   V KVAVNSGGKHCLAL + G VY+WG+ ED KLG   ++ P +    P +++SL   +++D+A GG+HSAAI+ SGELYTWGKGRYGRLGHG+ DDQ  PK+VEAL GY V  VACGSGDAQT  IT+ +          +VWSWGDGDYGKLGRGG D CK+P KIE+L G  ++KV+CGSQFS+ L+++G VYTWGKGDY RLGHG+D HVR+P+KV  L  KK+I ++ G+LHC+ CT+ GEVY+WGDNDEGQLGDGTTT   +PR++ +L  K INRV+CGSAHT+AW+T  G  +    S   RL  +T P   +LL++     L NR LLLHH+ E+ C  L  + L    +R+   SVM           D++R IL+ S+KE+ FR +VQ TM   ++HGP +++NR+        G S    AG                             TVF Q+  KL           S+     D  +LP+R WKVK +GESVDDCGGGYSESI E+C+ELQNG LP  I +P        ++DCF+L+P A+   N K F FLG L+GIAIRT  PLSL +++  WK L G  L+  DL   D+    +L  ++   + E    L  L +P+S ++  G +V L   +   I     NR+ Y+   +++++HEFD     +R+G+  V+PLPLL+LF+  ELE +VCG+  IP++ LKS+T Y+G++    ++ WFWE+MEE ++  RSLFLRFVWGRTRLPR ++D RG++FV+QVL KY+PAD +LPE+YTCFFLLK+P YS K +L+EKL YAIHFCKSID D+YAR+A
Sbjct: 2984 NQPLSSLNS--AKRVYVWGLNDKEQLGGPKGSKIKVPQAVDWMVSLQPINLAGGSKSLFLVTQSGKAYACGEGSNGRLGLGHSKNINT-----PHQIFALSQYVVRKIAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDVASLDTPRCVEALNGFRIRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVDALVGQRVLQVSCGSRDAQTLALVEGGLVYSWGDGDFGKLGRGGSEGCSSPCLVDKLSGLGVCHVECGAQFSVALTCNGHVYTWGKGDYFRLGHGSDQHVRWPTLVEGLRGKKVIGVSVGALHCLAVTDAGQVFAWGDNDHGQQGNGSVTVNRRPTLVQGIDGIKITRVACGSSHSVAWTAPEPPSVAPPE---------------------PVPFPTTKDPLGSTAAGLNEGSAEMGRHSAQPTKENSASLSRALLSLSSV---------EAQQRALHCVLY-SMQIQLCRDAVVAIFSQRATMNDDLLSQTG---PAQSTSDETDGEGSVEQFDGIKL---IKHKETAALWELLKLFSSNCKHSSSEARTTLSNALLAAAVKESSVRELLIEFCVAELEEV----SGEGTGIHHF-NAAGFGVGLGFPQ--PIVQESSHPYTDDVTLTGHVVLPGAESLRVEFDRQCSTEKRHDPLTLSDGVGRILAIRSGRDWADWSQEVRVQGNELRWRFTSDGSVNGWGWRFIVYPVISPGAAASGEVQS-------ERLLLARPSVSVVACLLDPLIKYLSCQSDSRKGRLPTRLAMALAGCAQRSGSLTPKDRMWALQRLRRILS------------------------------TP--GTCDAPASANYEASENAAVRSAV--SSTMMSPKDINHGTLGKLLRNLPEMLLQQYEYEEAAVRGGQQLLHSPFFQVLIALACDLRFDRL-PICTNDGSRWSWFRRYCAAARAATGLMQRTRLPESFTADVKRKISE-------IQSDDTNITA--DHENPLLFSHEHDQQLLQWMNSHPEDWTQSW--TAVGGGQIYGWGHNHRGQLGGVEGAKVKIPTVCEALSALRPIQLAGGEQTLFAVTSDGRVYATGYGAGGRLGIGGAESVTMPSLLESLQHVFVKKVAVNSGGKHCLALSSEGEVYSWGEGEDGKLGHGNKL-PCD---RPRIIESLRGKDVVDVACGGAHSAAITASGELYTWGKGRYGRLGHGDSDDQLKPKLVEALVGYRVKDVACGSGDAQTCAITEEDGG--------TVWSWGDGDYGKLGRGGSDGCKIPTKIESLSGKSIVKVECGSQFSVALSSNGSVYTWGKGDYHRLGHGADEHVRRPKKVMTLQGKKVISISTGALHCVVCTDQGEVYTWGDNDEGQLGDGTTTGIQKPRLVTALQNKKINRVSCGSAHTVAWSTCKGCTTPVAGS--SRLP-TTIPLQYDLLKDIPIPVLRNRLLLLHHFAEVVCPILPMLPLVSVHSREMDGSVMEETEGVLCGNHDRLRGILMASAKEAAFRKVVQATMIRDRQHGPVVELNRIALRRCRATGTS--GNAG--------------------------PNSTVFAQMANKL-----------SLLT--YDVLMLPHRTWKVKFVGESVDDCGGGYSESIAEMCEELQNGSLPLLILTPNGREEAGTNRDCFILNPSANSGQNLKMFQFLGVLMGIAIRTGSPLSLNLAEPTWKALVGLPLSLIDLNEIDRHYWPALCHIRDCKDAEGDLTLSQLDLPFSTSSAAGHDVALLPHSHRRI--TRDNRDLYLKLALHFRLHEFDGQVRAVRQGLGQVVPLPLLSLFTGAELEAMVCGSPEIPLALLKSVTTYKGIEPHCALVRWFWEVMEEYSHVERSLFLRFVWGRTRLPRTLADFRGRDFVLQVLDKYNPADYFLPESYTCFFLLKMPRYSCKVVLREKLSYAIHFCKSIDNDEYARVA 4799

HSP 2 Score: 333.954 bits (855), Expect = 4.798e-87
Identity = 200/416 (48.08%), Postives = 275/416 (66.11%), Query Frame = 2

Query: 12338 PREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-DIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTT 13582
            P +F ++H   +    KS+    +    ++SA    V+ WG N + QLGG +GSKIKVP   + + +L+P  + GG +SLF+V+  G+ YA G G+NGRLG+G ++++ TP  +  L + +V K+AV+SGG+H LAL  +G V++WG+ +D KLG  D+       + TP  V++L    I D+AAG +HSAA++ SGELYTWG G YGRLGHG+   Q  PK V+AL G  V+ V+CGS DAQTL           LV    V+SWGDGD+GKLGRGG + C  P  ++ L G GV  V+CG+QFS+ LT +G VYTWGKGDYFRLGHGSD HVR P  V  L  KK+I V+ G+LHC+  T+ G+V++WGDND GQ G+G+ T N RP +++ + G  I RVACGS+H++AWT 
Sbjct: 2964 PPDFEFEHADSVFN--KSQQSINQPLSSLNSAK--RVYVWGLNDKEQLGGPKGSKIKVPQAVDWMVSLQPINLAGGSKSLFLVTQSGKAYACGEGSNGRLGLGHSKNINTPHQIFALSQYVVRKIAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDV-----ASLDTPRCVEALNGFRIRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVDALVGQRVLQVSCGSRDAQTLA----------LVEGGLVYSWGDGDFGKLGRGGSEGCSSPCLVDKLSGLGVCHVECGAQFSVALTCNGHVYTWGKGDYFRLGHGSDQHVRWPTLVEGLRGKKVIGVSVGALHCLAVTDAGQVFAWGDNDHGQQGNGSVTVNRRPTLVQGIDGIKITRVACGSSHSVAWTA 3360

HSP 3 Score: 97.0561 bits (240), Expect = 1.836e-15
Identity = 78/227 (34.36%), Postives = 110/227 (48.46%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV-DGHQSMCL---SNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNE-IDQIQVHDSTYSVLLKS-GSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG 2260
            V  V  N    H LA++  G+VYSWG    GKLG G+     RP II++       V  VACG  HS  +T SG++Y+ G+   G+LGHGD  D+  P  + A  L+G  VK +A   G    C     + G +++WG   +    R  S+   KI T +     + I +++   S +SV L S GSVYTW K  Y    + +D+       V+  Q   V  IS G
Sbjct: 4019 VKKVAVNSGGKHCLALSSEGEVYSWGEGEDGKLGHGNKLPCDRPRIIESLR--GKDVVDVACGGAHSAAITASGELYTWGKGRYGRLGHGDSDDQLKPKLVEA--LVGYRVKDVACGSGDAQTCAITEEDGGTVWSWGDGDYGKLGRGGSDGC-KIPTKIESLSGKSIVKVEC-GSQFSVALSSNGSVYTWGKGDYHRLGHGADEHVRRPKKVMTLQGKKVISISTG 4239

HSP 4 Score: 80.8777 bits (198), Expect = 1.398e-10
Identity = 45/136 (33.09%), Postives = 69/136 (50.74%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
             RV+ V      +  LA+ E G VYSWG    GKLG+G ++    P ++D  S   L V  V CG + S+ LT +G +Y+ G+    +LGHG   D+H+        L G  V  ++V     + +++ G +F WG
Sbjct: 3185 QRVLQVSCGSRDAQTLALVEGGLVYSWGDGDFGKLGRGGSEGCSSPCLVDKLS--GLGVCHVECGAQFSVALTCNGHVYTWGKGDYFRLGHG--SDQHVRWPTLVEGLRGKKVIGVSVGALHCLAVTDAGQVFAWG 3316

HSP 5 Score: 76.6406 bits (187), Expect = 2.868e-9
Identity = 67/241 (27.80%), Postives = 107/241 (44.40%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRH---LSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDDI----QPELDTVLKYQVDNVSMISK----------------GDGEFYFLDKSG 2293
            ++  A +VY WG N   +LG       K P  +D      LQ   +A G +   ++TQSG  Y+CG    G+LG G  K+ + P +I A  L   +V++IAV   G  ++ L+ DG +F+WG   D    H    S  +P+    +N +R  I  +    +  + +  SG +YTW L         D++       +D ++  +V  VS  S+                GDG+F  L + G
Sbjct: 2989 SLNSAKRVYVWGLNDKEQLGGPKGSKIKVPQAVDWM--VSLQPINLAGGSKSLFLVTQSGKAYACGEGSNGRLGLGHSKNINTPHQIFA--LSQYVVRKIAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDVASLDTPRCVEALNGFR--IRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVDALVGQRVLQVSCGSRDAQTLALVEGGLVYSWGDGDFGKLGRGG 3223

HSP 6 Score: 76.2554 bits (186), Expect = 3.279e-9
Identity = 51/179 (28.49%), Postives = 89/179 (49.72%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRH---LSNWSPK-IETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            S  +  VT++G+ Y+ G  ++G+LG G +K+   P  I   S+  ++   V  G  H+L LT  G ++S G    G+LGHGDV     P  + A  L G  ++ +A   + S  +++ G ++TWG        H   L+  +PK ++  V +   ++      D+    L++ G VY+W
Sbjct: 3036 SKSLFLVTQSGKAYACGEGSNGRLGLGHSKNINTPHQIFALSQYVVRKIAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDVASLDTPRCVEA--LNGFRIRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVDALVGQRVLQVS-CGSRDAQTLALVEGGLVYSW 3211

HSP 7 Score: 74.7146 bits (182), Expect = 9.179e-9
Identity = 119/535 (22.24%), Postives = 205/535 (38.32%), Query Frame = 2

Query:  335 IFQNTMETFITYQDHVDSKIQNSDNLTKEQLIPETHNLFRSYQGKATGGL------------------LGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTD--TLPFWSGVTEQTYQFLKNTVLCPSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLKHIIMLIQL----SSGSKNYSHLTLTTGSDNGETMKPMITGQILSVLIRIAKFVKITTTNNNEITCARSTHLSSNPCLRLLDWMHLDNMKDDEPIDVDICLLNAAVYIMSCLDCLTIENQIAYSTWYKAHLVKHADSNVPNYKYENFLNTFCSSIEKSSHKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQL 1867
            +F+  +E     +   DS+I+   NL K++L  +  N+ R    +  G +                  L  V + + +  +F F +R W+ G + D   C E++  A+E ++ +P A  F++    D  T   W  +  ++  FL++ +   SS    IP   R  AL LLLE+ +  G+L   L  + +L++L     SG  N S+       + G    P+I      + +R    V+   T  +E         S + CL  L    L    +D   DVD+ L  AAV I++ LD L             A  ++   S+                           R     TL++ DL  S         D+          I++++C+ +   +LS  G +Y +          +T     I           +LK +S   V ++     +   + +T AGQVY+W           D+ D     + D        + +++CG E+ + L++ GDIY  G    GQL
Sbjct:  167 LFRRHIEEVRKVRHAEDSRIRGIGNLNKDEL--DKSNVQRKCVYEEIGSISAEKTKNPASSPQTIVATLTEVGSNAALNFLFAFFRRAWQSGEDGDA--CFELLIHALESLRSLPPASIFHLLHQKDNSTCDLWFRLLNKSVSFLRSIIFEESSCS--IPLRDRQVALQLLLEVSIQRGSLLCVLHAVHLLLELWDVEESGQDNRSN-------NRGLAFAPLI------LTLRRWSAVQQEQTGGSEKYSDEEYATSPSACL--LRQASLTPEPEDGDKDVDVDLYQAAVLILAHLDRLA------------APFIQPPLSD---------------------------RTVIENTLIRLDLNASTMA------DRYTEVHKLSITIEQMICTALGLLILSSDGKVYVIG---------YTDPEPTIR----------ILKSFSTFLVSEISFMAGACVCVILTHAGQVYAWPW-------MADSDDIPMMIMPDQ------DIVRISCGHEYGVALSEDGDIYIWGVQPGGQL 603

HSP 8 Score: 71.633 bits (174), Expect = 8.087e-8
Identity = 62/215 (28.84%), Postives = 94/215 (43.72%), Query Frame = 2

Query: 1385 PDKLPRELNEKFRIKKIV---CSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINH--QFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTE--AGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            P   PR + E  R K +V   C G  +  ++  G LY               ++  + H    D LK   V  L    RV DV      +   A+TE   G V+SWG    GKLG+G +   K PT I++ S     + +V CG + S+ L+ +G +Y+ G+    +LGHG   D H+        L G  V  I+      +  ++ G ++TWG
Sbjct: 4058 PCDRPR-IIESLRGKDVVDVACGGAHSAAITASGELYTWGKG----------RYGRLGHGDSDDQLKPKLVEAL-VGYRVKDVACGSGDAQTCAITEEDGGTVWSWGDGDYGKLGRGGSDGCKIPTKIESLS--GKSIVKVECGSQFSVALSSNGSVYTWGKGDYHRLGHG--ADEHVRRPKKVMTLQGKKVISISTGALHCVVCTDQGEVYTWG 4256

HSP 9 Score: 68.5514 bits (166), Expect = 7.430e-7
Identity = 66/259 (25.48%), Postives = 115/259 (44.40%), Query Frame = 2

Query: 1661 AGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVD--GHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTWLK----YCTECNKSDDIQPEL-DTVLKYQVDNVS------------------MISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIK 2359
             GQ+Y WG N  G+LG  +    K PT+ +  S   L+  Q+A GE+    +T  G +Y+ G    G+LG G  +   +P  + +  L  V VK++AV+  G   + LS++G +++WG   D    H +         +   R  ++  +    +  + +  SG +YTW K         +  D ++P+L + ++ Y+V +V+                  + S GDG++  L + G    K   KI     SG   +K
Sbjct: 3931 GGQIYGWGHNHRGQLGGVEGAKVKIPTVCEALSA--LRPIQLAGGEQTLFAVTSDGRVYATGYGAGGRLGIGGAESVTMPSLLES--LQHVFVKKVAVNSGGKHCLALSSEGEVYSWGEGEDGKLGHGNKLPCDRPRIIESLRGKDVVDVACGGAHSAAITASGELYTWGKGRYGRLGHGDSDDQLKPKLVEALVGYRVKDVACGSGDAQTCAITEEDGGTVWSWGDGDYGKLGRGGSDGCKIPTKI--ESLSGKSIVK 4183

HSP 10 Score: 66.2402 bits (160), Expect = 3.995e-6
Identity = 40/103 (38.83%), Postives = 56/103 (54.37%), Query Frame = 2

Query: 5660 DTPNYQLVMSD--SRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG--PNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRL 5956
            D  N Q+++ +  SR     +T  D +  L  S     + +K G  V+RG DWK+GDQDG  P    ++     +G VRVQW N   T SYR G+++ YDLRL
Sbjct: 1789 DISNVQVILDEGVSRRKGVTSTGNDCLATLALSGPEAAAMMKLGARVVRGPDWKWGDQDGTPPGEGRVIGDLGEDGWVRVQWYNG-ATNSYRMGREDKYDLRL 1890

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. TrEMBL
Match: E9GGZ0 (Uncharacterized protein OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_50378 PE=4 SV=1)

HSP 1 Score: 1359.74 bits (3518), Expect = 0.000e+0
Identity = 854/1967 (43.42%), Postives = 1163/1967 (59.13%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTC-------SQSTELTKKESDNLPSTA-------NKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLL---LVDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNE-----IELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLL-CLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTAD--EWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLN--------------RQSVM----DKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXK----AIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIA-----LNPDS 15139
            ++YVWGLNDK+QLG    SK+K+P   +    L  +S++GGSKSLF VT++GK Y  G+ SNGRLG+G   ++ +     P ++ AL ++ + KVAVHSGGRHA+ALT +G  FSWGEGDDGKLGH     L+ PR I+   G RV DVA GS+HSAA+   G LYTWGLG+YGRLGHGD   +L P+ V+SL   +VVQV+CGSRDAQTLAL     V+SWGDGDFGKLGRGGS GC  P  ++ +S   V  +ECGAQ S ALT NG V+TWGKGDY+RLGHG+D+H+R P  +E L+  K++ ++VGALHCLAVTD GQV++WGDNDHGQQGNG++T N RPTLV  +   KI  VACGSSHSVAWTA +  S  P +                     P+ F    DPLG+      + +    RN +  T ++                ++S     A Q  + C L+ ++Q+ + R+ V  + ++         SQ+ +     +D++   A        K +   E+  L ++ LKL ++    +    +  L N     +     V  LL    V E+E+     S +   IHH+ +   F   +   +   IV+ES HPY ++  L+G V++P A  L VEFDRQCSTE+  D L + D    I+A RSG+ W DW  +V + GNEL W F SDGS+  WGWRF V P+       +++         +E L L  P++ ++  LL+      I  Q     L  +L  +L+  A     L  + R+WA++++  I+                                                   S+     D S  +IN      G LL  L +++L+Q+++EE  V+  +QL +S FL+ LI L+C +R D + P+ T D   W+WFR YC   R    L+    LP  F  + K +  +          + +     +++ DP  FS++HD Q++ W+ S P+ W + W   +  G +++ WGHNHRGQLGGVEG+K+KVP +CE LSALRP Q+ GGEQ+LF ++ DGRVYATG+G  GRLGIG  ESV  P L+  L+   V KVAVNSGGKHCLAL + G VY+WG+ ED KLG   ++ P +    P +++SL   +++D+A GG+HSAAI+  GELYTWGKGRYGRLGHG+ DDQ  PK+VEAL GY V+ VACGSGDAQT  IT  E          +VWSWGDGDYGKLGRGG D CK+P KIE+L G G+IKV+CGSQFS+ L+ +G VYTWGKGDY RLGHG D HVR+P+KV  L  KK+I ++ G+LHC+ CT+ GEVY+WGDNDEGQLGDGTTT   +PR++ +L  K INRV+CGSAHT+AW+T  G  +    S   RL  S  P   +LL++    +L NR LLLHH+ E+ C  L  + L                + V+    D++R IL+ S+KE+ FR +VQ TM   ++HGP +++NR+        G S    AG                             TVF Q+  KL           S+     D  +LP+R WKVK +GESVDDCGGGYSESI E+C+ELQNG LP  I +P        ++DCF+L+P A    N K F FLG L+GIAIRT  PLSL +++  WK L G  L+  DL   D+    +L  ++    A  +  L  L +P+S ++  G+EV L+  T   I     NR+ Y+   +++++HEFD     +R+G+  V+PLPLL+LF+  ELE +VCG+  IP++ LKS+T Y+G++    ++ WFWE+MEE ++  RSLFLRFVWGRTRLPR ++D RG++FV+QVL KY+PAD +LPE+YTCFFLLK+P YS KA+L+EKL YAIHFCKSID D+YAR+A     LNP +
Sbjct: 2699 RVYVWGLNDKEQLGGPKGSKIKVPQAVDWTVSLQPISVAGGSKSLFLVTQSGKAYACGEGSNGRLGLGHSRNVNS-----PHQITALSQHVVRKVAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDVTSLDTPRCIEALNGFRVRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVESLVGQRVVQVSCGSRDAQTLALVEGGLVYSWGDGDFGKLGRGGSEGCSSPCLVDKLSGLGVCHVECGAQFSVALTCNGHVYTWGKGDYFRLGHGSDQHVRWPTLVEGLRGKKVIGVSVGALHCLAVTDAGQVFAWGDNDHGQQGNGSITVNRRPTLVQGIDGIKITRVACGSSHSVAWTAPEPPSVAPPE---------------------PVPFPTIKDPLGSTAAGLTESSAEMGRNSTQPTKENNASLS---------RALLSLSSLEAQQRALHCVLY-SMQIQLCRDAVVGIFSQQAVVNGDSPSQTGQAQLSPTDSINGEAPVEQFDWTKLIKHKETAAL-WELLKLSSSSCKPTSSEARTTLSNALLAAAAEESSVRDLLTEFCVAELEEV----SGEGTSIHHF-NAAGFGVGLGFPQ--PIVQESSHPYTDDVTLTGHVVLPGAESLRVEFDRQCSTEKRHDPLTLSDGVGRILAIRSGRDWADWSQEVRVQGNELRWRFTSDGSVNGWGWRFIVYPVISPGNFGEVQ---------SERLLLARPSVSVVACLLDPLIKYLICSQSRKGRLPTRLAMALAGCAQRSGSLTPKDRMWALQRLRRIL---------------------------------------------------STPGTCCDASPAVININHGTLGKLLRNLPEMLLQQYEYEEAAVRGGQQLLHSPFLQVLIALACDLRFDRL-PICTNDGSRWSWFRRYCAAARAATGLMQRIRLPESFTADVKRKISE---------IQNDGANVGNDHEDPVVFSHEHDQQLLQWMNSHPEDWTQSW--TAVGGGQIYGWGHNHRGQLGGVEGAKVKVPTVCEALSALRPIQLAGGEQTLFAITSDGRVYATGYGAGGRLGIGGAESVTVPSLLESLQHVFVKKVAVNSGGKHCLALSSEGEVYSWGEGEDGKLGHGNKL-PCD---RPRIIESLRGKDVVDVACGGAHSAAITALGELYTWGKGRYGRLGHGDSDDQLKPKLVEALLGYRVMDVACGSGDAQTCAITDEEGG--------TVWSWGDGDYGKLGRGGSDGCKIPTKIESLSGLGIIKVECGSQFSVALSNNGSVYTWGKGDYHRLGHGVDEHVRRPKKVMTLQGKKVISISTGALHCVVCTDQGEVYTWGDNDEGQLGDGTTTGIQKPRLVAALQNKKINRVSCGSAHTVAWSTCKGCSTPVAGS--SRLPTSI-PLQYDLLKDIPIPALRNRLLLLHHFAEIVCPILPMLPLGTVNCRDMDGNVLEETEGVLCGNHDRLRGILMASAKEAAFRKVVQATMIRDRQHGPVVELNRIALRRSRATGTS--GNAG--------------------------PNSTVFAQMANKL-----------SLLT--YDVLMLPHRTWKVKFVGESVDDCGGGYSESIAEMCEELQNGSLPLLILTPNGREEAGTNRDCFILNPSASTAQNLKMFQFLGVLMGIAIRTGSPLSLNLAEPTWKALVGLPLSLIDLNEIDRHYWPALCHIRDCKDADGDVTLSQLDLPFSTSSATGQEVALSPHTHRRI--TRDNRDLYLQLALHFRLHEFDPQVRAVRQGLGQVVPLPLLSLFTGAELEAMVCGSPEIPLALLKSVTTYKGIEPHCALVRWFWEVMEEYSHVERSLFLRFVWGRTRLPRTLADFRGRDFVLQVLDKYNPADYFLPESYTCFFLLKMPRYSCKAVLREKLSYAIHFCKSIDNDEYARVAAPEVLLNPPA 4491

HSP 2 Score: 337.806 bits (865), Expect = 2.867e-88
Identity = 197/390 (50.51%), Postives = 265/390 (67.95%), Query Frame = 2

Query: 12419 PIDSASGLE-VWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-DIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTT 13582
            PI S SG + V+ WG N + QLGG +GSKIKVP   +   +L+P  + GG +SLF+V+  G+ YA G G+NGRLG+G + +V +P  ++ L + +V KVAV+SGG+H LAL  +G V++WG+ +D KLG  D+       + TP  +++L    + D+AAG +HSAA++ SGELYTWG G YGRLGHG+   Q  PK VE+L G  V+ V+CGS DAQTL           LV    V+SWGDGD+GKLGRGG + C  P  ++ L G GV  V+CG+QFS+ LT +G VYTWGKGDYFRLGHGSD HVR P  V  L  KK+I V+ G+LHC+  T+ G+V++WGDND GQ G+G+ T N RP +++ + G  I RVACGS+H++AWT 
Sbjct: 2690 PISSVSGAKRVYVWGLNDKEQLGGPKGSKIKVPQAVDWTVSLQPISVAGGSKSLFLVTQSGKAYACGEGSNGRLGLGHSRNVNSPHQITALSQHVVRKVAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDV-----TSLDTPRCIEALNGFRVRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVESLVGQRVVQVSCGSRDAQTLA----------LVEGGLVYSWGDGDFGKLGRGGSEGCSSPCLVDKLSGLGVCHVECGAQFSVALTCNGHVYTWGKGDYFRLGHGSDQHVRWPTLVEGLRGKKVIGVSVGALHCLAVTDAGQVFAWGDNDHGQQGNGSITVNRRPTLVQGIDGIKITRVACGSSHSVAWTA 3064

HSP 3 Score: 111.309 bits (277), Expect = 9.676e-20
Identity = 76/270 (28.15%), Postives = 126/270 (46.67%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRI--MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRT----GKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +Y+W +    KL        + P        ++ V+        + I  + ++Y WG     +LG   +     P L EAL     + ++ GS        T    G V+  GD   G+LG G            P ++E+L    I+K  V  G + ++AL+ NG  ++WG+GD  +LGH     +  P+K+   +GK+V+ ++ G+ H       G +YTWG  D G+LG G T     P LV +L++ K+ +V+CGS  A T+A ++
Sbjct: 3722 VYSWGEGEDGKLGHGNKLPCDRPRIIESLRGKDVVDVACGGAHSAAITALGELYTWGKGRYGRLGHGDSDDQLKPKLVEALLGYRVMDVACGSGDAQTCAITDEEGGTVWSWGDGDYGKLGRGGSDGCKI-----PTKIESLSGLGIIK--VECGSQFSVALSNNGSVYTWGKGDYHRLGHGVDEHVRRPKKVMTLQGKKVISISTGALHCVVCTDQGEVYTWGDNDEGQLGDGTTTGIQKPRLVAALQNKKINRVSCGS--AHTVAWST 3982

HSP 4 Score: 92.0485 bits (227), Expect = 6.135e-14
Identity = 70/193 (36.27%), Postives = 97/193 (50.26%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV-DGHQSMCLSND---GAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLLK-SGSVYTWLK 2164
            V  V  N    H LA++  G+VYSWG    GKLG G+     RP II++       V  VACG  HS  +T  G++Y+ G+   G+LGHGD  D+  P  + A  L+G  V  +A   G    C   D   G +++WG   +    R  S+   KI T + E  + +  I+V   S +SV L  +GSVYTW K
Sbjct: 3701 VKKVAVNSGGKHCLALSSEGEVYSWGEGEDGKLGHGNKLPCDRPRIIESLR--GKDVVDVACGGAHSAAITALGELYTWGKGRYGRLGHGDSDDQLKPKLVEA--LLGYRVMDVACGSGDAQTCAITDEEGGTVWSWGDGDYGKLGRGGSDGC-KIPTKI-ESLSGLGIIKVECGSQFSVALSNNGSVYTWGK 3887

HSP 5 Score: 85.5001 bits (210), Expect = 5.449e-12
Identity = 110/460 (23.91%), Postives = 191/460 (41.52%), Query Frame = 2

Query:  485 LGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTD--TLPFWSGVTEQTYQFLKNTVLCPSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLKHIIMLIQL----SSGSKNYSHLTLTTGSDNGETMKPMITGQILSVLIRIAKFVKITTTNNNEITCARSTHLSSNPCLRLLDWMHLDNMKDDEPIDVDICLLNAAVYIMSCLDCLTIENQIAYSTWYKAHLVKHADSNVPNYK---YENFLNTFCSSIEKSSHKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIY 1837
            L  V + + +  +F F +R W+ G + D   C E++  A+E ++ +P    F++    D  T   W  + +++  FL++ V     N   IP   R  AL LLLE+ +  G+L   L+ + +L++L     SG  N S+       + G T+ P+I       L R +   +  T ++ E         +++P   LL    L    +D   DVD+ L  AAV I+                   AHL + A   +  +K   Y NF N+  + +E +      IRL  S   +       +F +V+    KLP        I ++VC+ +   +LS  G +Y +                + N Q   L+N   L  +S   V ++     +     +T +GQVY W           D+ D     II         + +++CG+E+ + L+++G+IY
Sbjct:    4 LTEVGSNAALNFLFAFFRRAWQSGEDGDA--CFELLVHALESLRSLPPTSIFHLLHQRDNNTFGLWFRLLDKSTSFLRSIVF--EENSCSIPLRDRQVALQLLLEISIQRGSLLCVLQTVHLLLELWDVEESGQDNRSN-------NRGLTVAPLIL-----TLRRWSAVQQGQTGSSKEYI---DEMYATSPSACLLRQASLSPEPEDGDKDVDVDLYQAAVLIL-------------------AHLDRLASPFIQTFKSVFYFNFANSLQTFMENT-----LIRLDLSAATV------DRFTVVQ----KLP------ITIDQVVCTALGLLILSGDGKVYTI----------------SYNDQEPTLRN---LNCFSAFPVAEIGFMAGNCVCAVLTHSGQVYLWPWME-------DSDDNPTMVIIS-----DQDIVRISCGDEYGVALSKNGEIY 373

HSP 6 Score: 81.2629 bits (199), Expect = 9.700e-11
Identity = 45/136 (33.09%), Postives = 69/136 (50.74%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
             RV+ V      +  LA+ E G VYSWG    GKLG+G ++    P ++D  S   L V  V CG + S+ LT +G +Y+ G+    +LGHG   D+H+        L G  V  ++V     + +++ G +F WG
Sbjct: 2889 QRVVQVSCGSRDAQTLALVEGGLVYSWGDGDFGKLGRGGSEGCSSPCLVDKLS--GLGVCHVECGAQFSVALTCNGHVYTWGKGDYFRLGHG--SDQHVRWPTLVEGLRGKKVIGVSVGALHCLAVTDAGQVFAWG 3020

HSP 7 Score: 79.7221 bits (195), Expect = 2.856e-10
Identity = 53/179 (29.61%), Postives = 90/179 (50.28%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRH---LSNWSPK-IETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            S  +  VT++G+ Y+ G  ++G+LG G +++   P  I   S+  ++   V  G  H+L LT  G ++S G    G+LGHGDV     P  I A  L G  V+ +A   + S  +++ G ++TWG        H   L+  +PK +E+ V +   ++      D+    L++ G VY+W
Sbjct: 2740 SKSLFLVTQSGKAYACGEGSNGRLGLGHSRNVNSPHQITALSQHVVRKVAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDVTSLDTPRCIEA--LNGFRVRDVAAGSNHSAAVTSSGELYTWGLGEYGRLGHGDNLTQLTPKRVESLVGQRVVQVS-CGSRDAQTLALVEGGLVYSW 2915

HSP 8 Score: 77.7962 bits (190), Expect = 1.036e-9
Identity = 56/176 (31.82%), Postives = 89/176 (50.57%), Query Frame = 2

Query: 1649 AVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIID-TFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRH---LSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ A +VY WG N   +LG       K P  +D T S   LQ   VA G +   ++TQSG  Y+CG    G+LG G  ++ + P +ITA  L   +V+++AV   G  ++ L+ DG +F+WG   D    H    S  +P+    +N +R  +  +    +  + +  SG +YTW
Sbjct: 2693 SVSGAKRVYVWGLNDKEQLGGPKGSKIKVPQAVDWTVS---LQPISVAGGSKSLFLVTQSGKAYACGEGSNGRLGLGHSRNVNSPHQITA--LSQHVVRKVAVHSGGRHALALTADGRVFSWGEGDDGKLGHGDVTSLDTPRCIEALNGFR--VRDVAAGSNHSAAVTSSGELYTW 2861

HSP 9 Score: 74.7146 bits (182), Expect = 1.107e-8
Identity = 63/215 (29.30%), Postives = 96/215 (44.65%), Query Frame = 2

Query: 1385 PDKLPRELNEKFRIKKIV---CSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINH--QFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVT--EAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            P   PR + E  R K +V   C G  +  ++  G LY               ++  + H    D LK   V  L    RV+DV      +   A+T  E G V+SWG    GKLG+G +   K PT I++ S   L + +V CG + S+ L+ +G +Y+ G+    +LGHG   D H+        L G  V  I+      +  ++ G ++TWG
Sbjct: 3740 PCDRPR-IIESLRGKDVVDVACGGAHSAAITALGELYTWGKG----------RYGRLGHGDSDDQLKPKLVEALLGY-RVMDVACGSGDAQTCAITDEEGGTVWSWGDGDYGKLGRGGSDGCKIPTKIESLS--GLGIIKVECGSQFSVALSNNGSVYTWGKGDYHRLGHG--VDEHVRRPKKVMTLQGKKVISISTGALHCVVCTDQGEVYTWG 3938

HSP 10 Score: 70.8626 bits (172), Expect = 1.364e-7
Identity = 68/259 (26.25%), Postives = 115/259 (44.40%), Query Frame = 2

Query: 1661 AGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVD--GHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTWLK----YCTECNKSDDIQPEL-DTVLKYQVDNVS------------------MISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIK 2359
             GQ+Y WG N  G+LG  +    K PT+ +  S   L+  Q+A GE+    +T  G +Y+ G    G+LG G  +   +P  + +  L  V VK++AV+  G   + LS++G +++WG   D    H +         +   R  ++  +    +  + +   G +YTW K         +  D ++P+L + +L Y+V +V+                  + S GDG++  L + G    K   KI     SG G IK
Sbjct: 3613 GGQIYGWGHNHRGQLGGVEGAKVKVPTVCEALSA--LRPIQLAGGEQTLFAITSDGRVYATGYGAGGRLGIGGAESVTVPSLLES--LQHVFVKKVAVNSGGKHCLALSSEGEVYSWGEGEDGKLGHGNKLPCDRPRIIESLRGKDVVDVACGGAHSAAITALGELYTWGKGRYGRLGHGDSDDQLKPKLVEALLGYRVMDVACGSGDAQTCAITDEEGGTVWSWGDGDYGKLGRGGSDGCKIPTKI--ESLSGLGIIK 3865

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Cavefish
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-070718-6])

HSP 1 Score: 995.342 bits (2572), Expect = 0.000e+0
Identity = 601/1321 (45.50%), Postives = 807/1321 (61.09%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L VEFDRQCSTER  D L +MD  N IV+ RSG+ W DW S++ I G+EL W F SDGS+  WGWRF V P+        +  D            L  P++ L+  LL+   L F  + S+  +L  SL+  A     L    R+WA++++  ++         ++ ++I+   +L  +  +++           P +F   A                      +   +  L + + +Q+++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC   R   +L   + LP  F++E   + ++E          +N +    E      F  +HD Q+V W+  RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP   E L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ SGELYTWGKGRYGRLGHG+ +DQ  PK+V+AL+G+ VI VACGSGDAQTLC+T ++           VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYTWGKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTEDGEVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+    ++L NR LLLHH +ELFC  +   DL  +        SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK +GESVDDCGGGYSESI E+C+ELQNG  P  I +P        ++DCF+L+P A    +   F FLG LLGIAIRT  PLSL +++ +WK L+G +L   DL   DKD +  LM ++  + +  E E + +P++V    G+EV L+ + S    ++  NR  Y+   INY++HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+GV+    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FV+QVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL+
Sbjct: 3607 VVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGANRIVSVRSGREWSDWSSELRIPGDELKWKFTSDGSVNGWGWRFTVYPIMPAAGPKDLLSDRC---------ILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLAACA-QLSALAAGHRMWALQRLRKLLTT-------EYGQSININRLLGDSEGEAR-----------PMSFTGSA----------------------LAALVKGLPEALQRQYEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCTASRVAVALDKRTPLPRLFLDEVAKK-IRELMADH---ENMNGLHESHEL-----FKREHDEQLVQWMNRRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-SPCD---RPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDD----------MVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPTNAGKLPAQ------VPMEYNHLQEIPIMALRNRLLLLHHISELFCPCIPMFDLEGRLGQTGQGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPAAKSPLHMSMFRFLGVLLGIAIRTGSPLSLYLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEASAEEFEAMPLPFTVPNACGQEVQLSSKYS---HISLENRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGVEPTAPLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVVQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKLVLEEKLKYAIHFCKSIDTDDYARIALS 4797

HSP 2 Score: 480.715 bits (1236), Expect = 7.433e-135
Identity = 270/541 (49.91%), Postives = 351/541 (64.88%), Query Frame = 2

Query: 9299 LNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKS--RIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTCSQSTE 10915
            L  + F  + N E+     D  +  ++  + +S  +S   I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V +SGGSKSLF VT  GKVY  G+++NGRLG+G    +++  I  P+++ AL  Y + KVAVHSGGRHA+ALT +G+ FSWGEGDDGKLGH SR+  + PR I+  K KR+ D+ACGSSHSAAI   G LY+WGLG+YGRLGHGD   +L P+LVK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWTWGKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVT+ GQV++WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA     +  +       +  + Q+       + N  +L+ ++  L G   +   +  +   LQ++ AR+ V   +   C    E
Sbjct: 2913 LATVPFLASDNEEE---EDDKAATGSLARKRSSGLESAASIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVSGGSKSLFAVTAEGKVYACGEATNGRLGLG----LSSGTIPIPRQVSALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVTT----------PSVHE-----------PVLFQTARDSLGA-SYLGVPSDSDPSSLSNKLSGQNS-----VKPNRPSLAKILLSLDGNLAKQQALSHVLSALQIMYARDAVVGALMPACMMPVE 3419

HSP 3 Score: 375.17 bits (962), Expect = 6.249e-103
Identity = 196/393 (49.87%), Postives = 266/393 (67.68%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEM 10597
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G LYTWG G YGRLGHGD+  +L P+LV +L+ ++V+ VACGS DAQTL LT D  VWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+TWGKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+ G+VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   LP+Q    + H++E+
Sbjct: 3949 IYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPTNAGKLPAQVPMEYNHLQEI 4336

HSP 4 Score: 357.066 bits (915), Expect = 1.907e-97
Identity = 211/398 (53.02%), Postives = 277/398 (69.60%), Query Frame = 2

Query: 12401 AWKKCWPIDSASGL--EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            A K+   ++SA+ +  +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF V+ +G+VYA G   NGRLG+G S+ ++  P  VS L   +V KVAV+SGG+H +AL  +G V++WG+ +D KLG   R+    +   P L+++L    I DIA G SHSAAI+ SGELY+WG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T              V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+TWGKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  TE G+V++WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2937 ARKRSSGLESAASIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVSGGSKSLFAVTAEGKVYACGEATNGRLGLGLSSGTIPIPRQVSALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRM----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDE----------GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3320

HSP 5 Score: 277.715 bits (709), Expect = 1.719e-73
Identity = 161/377 (42.71%), Postives = 224/377 (59.42%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRV----VDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  +ALS L    I    K    ++ +G VY     S                 + P  +  L    IVK+A H  G+H +AL+ NGE FSWG GD G+LGH     L  P  I  F GK+V    V +ACGS++SAAI   G L+TWG G+YGRLGHG +  +  P LV +L+  KV+ VACGS DAQTL++T +  VWSWGDGD+GKLGRGGS GC  P+ +E +   +++++ CG+Q S ALT++GQV+TWGKGD  RLGHGTD+H+R P  ++ L+  K+V +AVG+ HCLA+T+ G+V+SWG ND  Q  +   +   +P  +  L    I  ++CG   S AW++
Sbjct:  421 LQEVIGWGL-----LGWKVYANVNGPIQCKALSSLGVTQIVCSEKGFLILSISGAVYTQNYKST---------------TLSPMLVHGLSSRKIVKLAAHPEGQHYLALSANGEVFSWGCGDGGRLGHGDTTYLEEPTMIAAFSGKQVGKHVVHIACGSTYSAAITADGELFTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKSPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKKVVDIAVGSTHCLALTEDGEVHSWGSNDKLQHFDTLFSNKKQPKALPGLNSKHIVGISCGPGQSFAWSS 777

HSP 6 Score: 264.618 bits (675), Expect = 1.782e-69
Identity = 167/382 (43.72%), Postives = 227/382 (59.42%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            EV  WG      LG    + +  P+ C+ LS+L   QI+  E+   I+SI G VY   + +          +  +P+LV GL  + +VK+A +  G+H LAL  NG V++WG  +  +LG        E  +        V   ++ IA G ++SAAI+  GEL+TWG+G YGRLGHG+ +DQ  P +V AL+G  VI VACGSGDAQTL +T+N            VWSWGDGDYGKLGRGG D CK P  +E L+   ++KV CGSQFS+ LT  G+VYTWGKGD  RLGHG+D HVR P+ +  L  KK++D+A GS HC+  TEDGEV+SWG ND+ Q  D   +   +P+ +  L  K I  ++CG   + AW++ S
Sbjct:  423 EVIGWG-----LLGWKVYANVNGPIQCKALSSLGVTQIVCSEKGFLILSISGAVYTQNYKS----------TTLSPMLVHGLSSRKIVKLAAHPEGQHYLALSANGEVFSWGCGDGGRLGHGDTTYLEEPTMIAAFSGKQVGKHVVHIACGSTYSAAITADGELFTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLSVTEN----------GQVWSWGDGDYGKLGRGGSDGCKSPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQGKKVVDIAVGSTHCLALTEDGEVHSWGSNDKLQHFDTLFSNKKQPKALPGLNSKHIVGISCGPGQSFAWSSCS 779

HSP 7 Score: 137.887 bits (346), Expect = 3.145e-31
Identity = 90/264 (34.09%), Postives = 133/264 (50.38%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFA 10213
            ++Y WG  +  +LG    S    P + E+L  ++ V I+ G     C+T +G++Y  G    GRLG G   D      + PK ++AL  + ++ VA  SG    + LT +   +SWG+GD GKLG         P KI    G  VV V CGS  S A+   G +YTWG GDY RLGHG       P  V+ L+  KV+ +A GS     +  T D  V++WGD D G+LG G ++    P+ +  +    + ++ CG+  + A
Sbjct: 4054 EVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSED-----QLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGS--LHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLA 4310

HSP 8 Score: 121.709 bits (304), Expect = 2.629e-26
Identity = 91/265 (34.34%), Postives = 134/265 (50.57%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SWG+ + GKLG G  S C  P+ IE +    V+ I  G   S  +T +G+++TWGKG Y RLGHG  +   +P  ++ L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3946 SGTIYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4210

HSP 9 Score: 102.834 bits (255), Expect = 1.273e-20
Identity = 63/197 (31.98%), Postives = 107/197 (54.31%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL--QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQV-HDSTYSVLL-KSGSVYTWLK 2164
            S  +++ + A+    H LA++  G+V+SWG    G+LG GDT   + PT+I  FS   +   V  +ACG  +S  +T  G++++ GR + G+LGHG  +D+  P+ +TA   + V+         Q++ ++ +G +++WG   +    R  S+   SPK+     E   ++D ++V   S +SV L K G VYTW K
Sbjct:  490 SSRKIVKLAAHPEGQHYLALSANGEVFSWGCGDGGRLGHGDTTYLEEPTMIAAFSGKQVGKHVVHIACGSTYSAAITADGELFTWGRGNYGRLGHGSSEDQTTPMLVTALKGLKVIDVACGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKSPKL----VEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGK 682

HSP 10 Score: 101.679 bits (252), Expect = 2.965e-20
Identity = 139/547 (25.41%), Postives = 228/547 (41.68%), Query Frame = 2

Query: 4529 LNLVALVKHVNLCE---ELANHI---MRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEV--------------EILS-------INNSAINAGRKKSININDFTSDHLTATPPTTRWKS------------IAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGKIRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQ--ILRENLLVNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQL---VMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL-------KKSIEDVKNETPSE 5998
            L L  L+KH +L      L N     + Q  ++ +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+              ++LS       I    I   RKK +     ++D         R  +               K  + +K PK   D WQ + N V      K R  K +    V    +     G I +F L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++L  +   +      E  N  E + D LK    +  FN + L      L   YS  + +++  +L  ++   +  ++ +    + N       +G    A+  L++   L  T+    +   LLL +G L L Q++LR    S          D+    L   V   S  +  E+ K      L +S   L + +K GT V+RG+DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L       + ++ED   E  +E
Sbjct: 1431 LLLCCLLKHQDLGHVALSLVNQCALAVDQGKQRSLPKSVIDVCRMVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVSNYLSIVCKLKLLSSQPRWKMITRKLIRECRKKRVPKKSESADVEECKQEREREGTNEEEPPPPISPTPVDKKQITVKSPK---DKWQPLLNTVAT--VQKYRWLKHS----VQGPCSQSSLMGTIVEFALKEEPLDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LTSKGFLLPSVQYAMLCGWQRVIP-----EGPNIGEPLSDCLKDVYLIPPFNRMLLEVTFGKL---YSWAIQNVRNILLEASVKFKELGVQPVPLQTITNENPAGPSLGTIPQARFLLAMLQIL--TLKHGANSLSLLLNSGALALTQSVLRLIGPS---------SDSTEEDLSSGVHGGSATVLEESRKETVPAPLPASGPELAAMMKIGTRVMRGQDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTSSTNSYRMGKEGKYDLKLAEPPPATQPAMEDSDTEDDTE 1943

HSP 11 Score: 97.0561 bits (240), Expect = 6.345e-19
Identity = 78/244 (31.97%), Postives = 116/244 (47.54%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYTWLK--YCTECNKSDDIQPELDTVLKYQVDNVSMISKG---------DGEFY 2275
            V  N    H LA++  G+VYSWG    GKLG G+     RP +I++     ++V  +A G  HS  +T SG++Y+ G+   G+LGHGD +D+  P  + A  L G  V  +A      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYTW K  Y    + SDD       V   Q   V  I+ G         DGE Y
Sbjct: 4037 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLR--GVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVDA--LQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVY 4266

HSP 12 Score: 86.2705 bits (212), Expect = 1.344e-15
Identity = 56/178 (31.46%), Postives = 87/178 (48.88%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGH--QSMCLSNDGAIFTWG-STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            H +A+T  G+V+SWG    GKLG     +  +P +I+       +++ +ACG  HS  +T SG++YS G    G+LGHGD   +  P  +    L+G  V Q+A      Q++ L+++G +F+WG   F    R  S      +         + QI+        L KSG V+TW K
Sbjct: 3051 HAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKV--LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGK 3224

HSP 13 Score: 86.2705 bits (212), Expect = 1.378e-15
Identity = 49/136 (36.03%), Postives = 72/136 (52.94%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            +VIDV      +  L+VTE GQV+SWG    GKLG+G +   K P +++      L + +V CG + S+ LT+ G +Y+ G+    +LGHG   D H+        L G  V  IAV     + L+ DG + +WGS
Sbjct:  603 KVIDVACGSGDAQTLSVTENGQVWSWGDGDYGKLGRGGSDGCKSPKLVEKLQ--DLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHG--TDEHVRYPKLLDSLQGKKVVDIAVGSTHCLALTEDGEVHSWGS 734

HSP 14 Score: 82.0333 bits (201), Expect = 2.473e-14
Identity = 49/136 (36.03%), Postives = 71/136 (52.21%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVIDV      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + DG ++TWG
Sbjct: 4138 HRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGS--DDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4269

HSP 15 Score: 78.5666 bits (192), Expect = 2.330e-13
Identity = 44/136 (32.35%), Postives = 77/136 (56.62%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+D+ A    +H   +T +G++Y+WG    G+LG GD++D+ +P ++D   + H +V  VAC  G+  +L LT    ++S G    G+LG G      +P++I +  L G+ V ++      S+ L+  GA++TWG
Sbjct: 4088 VVDIAAG--GAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKLVDAL-QGH-RVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGLGVVKVECGSQFSVALTKSGAVYTWG 4217

HSP 16 Score: 78.5666 bits (192), Expect = 2.470e-13
Identity = 61/211 (28.91%), Postives = 100/211 (47.39%), Query Frame = 2

Query: 1394 LPRELN--EKFRIKKIVC--SGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +PR+++    + +KK+     G     L+  G ++      D  +  F+        + +C K   +  L +K R+ D+     SSH  A+T +G++YSWG    G+LG GD   + RP ++        +V QVACG  +  +L LT  G ++S G    G+LG G  +  ++P  I    L G  V QI      S+ L+  G ++TWG
Sbjct: 3028 IPRQVSALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFS--------RMNCDKPRLIEALKTK-RIRDIACG--SSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVL--LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNI--ERLNGQGVCQIECGAQFSLALTKSGVVWTWG 3223

HSP 17 Score: 75.8702 bits (185), Expect = 1.610e-12
Identity = 53/197 (26.90%), Postives = 90/197 (45.69%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+ G V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + ++  G +F WG
Sbjct: 3093 RIRDIACGSSHSAAITSSGELYSWGLG----------EYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG--TDVHVRKPQMVEGLRGKKIVHVAVGALHCLAVTETGQVFAWG 3275

HSP 18 Score: 74.3294 bits (181), Expect = 4.359e-12
Identity = 66/235 (28.09%), Postives = 105/235 (44.68%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV--DGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSDD---IQPEL-DTVLKYQVDNVSMISK----------------GDGEFYFLDKSG 2293
            +V+ WG N   +LG       K P+  +T S   L V QV+ G +    +T  G +Y+CG    G+LG G +    +PI    S L   +VK++AV   G  +M L+ DG +F+WG   D    H S  +   P++   +   R  I  I    S  + +  SG +Y+W L         D+   ++P+L   +L ++V  V+  S+                GDG+F  L + G
Sbjct: 2953 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVSGGSKSLFAVTAEGKVYACGEATNGRLGLG-LSSGTIPIPRQVSALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKR--IRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGG 3182

HSP 19 Score: 66.6254 bits (161), Expect = 9.392e-10
Identity = 69/242 (28.51%), Postives = 103/242 (42.56%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSN---WSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIK 2359
            + AVT  G++Y+ G    G+LG G T+    PT++++     ++   V  G +H L L+  G++YS G    G+LGHG+      P R+  S L GV V  IA  G  S C++  G ++TWG        H  +     PK+          +D +Q H     V   SG   T       C   DD+                + S GDG++  L + G    K  MKI     +G G +K
Sbjct: 3992 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIRKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRSPCDRP-RVIES-LRGVEVVDIAAGGAHSACITASGELYTWGKGRYGRLGHGDSEDQLKPKL----------VDALQGH-RVIDVACGSGDAQTL------CLTDDDM----------------VWSWGDGDYGKLGRGGSDGCKVPMKI--DSLTGLGVVK 4196

HSP 20 Score: 55.0694 bits (131), Expect = 2.970e-6
Identity = 33/123 (26.83%), Postives = 59/123 (47.97%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVI------DTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+      D F   H    H    ++   +++     +++ V   + + H LAVTE GQV++WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3204 ECGAQFSLALTKSGVVWTWGKGDYFRLGHGTDVH----VRKPQMVEGLRGKKIVHV--AVGALHCLAVTETGQVFAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3318

HSP 21 Score: 53.5286 bits (127), Expect = 9.505e-6
Identity = 37/126 (29.37%), Postives = 60/126 (47.62%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S  + AVT  G+VY+ G  T+G+LG G  +     P  +   S   ++   V  G  H++ LT  G ++S G    G+LGH    +   P  I A  L    ++ IA     S  +++ G +++WG
Sbjct: 2994 SKSLFAVTAEGKVYACGEATNGRLGLGLSSGTIPIPRQVSALSNYVVKKVAVHSGGRHAMALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEA--LKTKRIRDIACGSSHSAAITSSGELYSWG 3117

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Cavefish
Match: ENSAMXT00000014806.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000133.1:558903:571495:-1 gene:ENSAMXG00000014386.2 transcript:ENSAMXT00000014806.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 222.631 bits (566), Expect = 5.505e-61
Identity = 136/344 (39.53%), Postives = 211/344 (61.34%), Query Frame = 2

Query: 14129 LPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYAD-KTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETEL--ENLQ--IP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I SP        ++D F+L+P A  + +   F FLG L+G+AIRT +PL L ++ L+WK L    L   DL+  D   + +L S+  +++T +  +N    IP   +   + DGK V + I    +I +  SNR  Y++  I Y++HE D+    +R G+S ++P+PLL+L ++R+LE +VCG   I +  LK +  YR V+    ++ WFW+ +EE +NE R LF+RFV GR+RLP   +D+  +    Q++  Y    D LP + TCFF L+LP YSS++++ E+L YAI+ C+SID+D+Y
Sbjct:  202 LPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPMPTAEVGYNRDRFLLNPSACLEEHLLQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCIPLTLEDLEEVDLLYVQTLNSILHLEDTSITEQNFHEMIPLDSFVGQSADGKMVPI-IPGGNSIPLTFSNRKEYVERAIEYRLHEIDRQVAAVREGMSWIVPVPLLSLLTARQLEQMVCGLPEISVEVLKKVVRYREVEEQQQLVQWFWQTLEEFSNEERVLFMRFVSGRSRLPANTADISQR---FQIMKPY----DSLPTSQTCFFQLRLPPYSSQSLMAERLRYAINNCRSIDMDNY 537

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Cavefish
Match: herc4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4 [Source:NCBI gene;Acc:103028096])

HSP 1 Score: 154.451 bits (389), Expect = 1.129e-36
Identity = 100/325 (30.77%), Postives = 169/325 (52.00%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDT--AMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXX-XXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD--LDSF 10552
            G++S G+LG+G    I  E+++ P++    +   +  V    G RH + L  +G  ++ G  D G+LGH    K   P ++     + +V V+CG SH+ A+   G ++ WG    G+LG  +    +R+ P  +KSL +  +VQV CG R   +LAL+    ++SWG   +G+LG G      L PQ ++ +      QI  G   SF LT +G V+ WG+  + +LG   +     P  ++ L+  ++V++  G  H  A+T  G V+++G   +GQ G+ T  + + P  V  LM N +  ++CG  H++A+  S   +DSF
Sbjct:    5 GNASYGQLGLGG---IDEEIVVEPRKCSFFNGKLVWDVGC--GRRHTVFLLGDGTVYTCGCNDLGQLGHEKTRK--KPEQVVALDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRV-PRNIKSLSEVHIVQVTCGYR--HSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSSGKIDSF 319

HSP 2 Score: 112.079 bits (279), Expect = 1.180e-23
Identity = 63/216 (29.17%), Postives = 111/216 (51.39%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSK-VKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +++ WG   + QLG       V++P   ++LSE+  V ++ G +    ++R G+++  G +  G+LG+G +       ++ P+ +++L    I    + +GG H+  LT +G  F WG    G+LG N       P  +K  + +RVV + CG  H+AA+   G ++T+G G YG+LGH  T   ++P  V  L    V Q++CG +       +S
Sbjct:  104 QVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKE----GPSVLTPQLVQSL--LGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSS 313

HSP 3 Score: 102.834 bits (255), Expect = 7.189e-21
Identity = 93/330 (28.18%), Postives = 160/330 (48.48%), Query Frame = 2

Query: 12614 GFGNNGRLGIGST--ESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKL-PMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            G  + G+LG+G    E V  P   S    K+V  V    G +H + L  +G VY  G  +  +LG +   +  E V+      +L    I+ ++ G SH+ A++  G+++ WG+   G+LG  N +D    P+ +++L   H++ V CG     +L +++             ++SWG   YG+LG G      L P  +++L G    ++  G   S  LT SG V+ WG+  + +LG   ++    P  +  L  ++++ + CG  H    T++G V+++G    GQLG  TT     PR +  L G  + +++CG  HT+A+   SG
Sbjct:    5 GNASYGQLGLGGIDEEIVVEPRKCSFFNGKLVWDVGC--GRRHTVFLLGDGTVYTCGCNDLGQLGHEKTRKKPEQVV------ALDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGY--RHSLALSRR----------GQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSSG 314

HSP 4 Score: 100.908 bits (250), Expect = 2.666e-20
Identity = 68/212 (32.08%), Postives = 106/212 (50.00%), Query Frame = 2

Query: 9914 LYTWGLGDYGRLGHG--DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLG-HGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYN-MRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +  WG   YG+LG G  D  + + P          V  V CG R   T+ L  D TV++ G  D G+LG   +     P+++  +   N++ + CG   + AL + GQV+ WG+    +LG    +  +R P  I+ L +  IV +  G  H LA++ RGQ++SWG N +GQ G G    + + P LV +L+    A ++ G +HS   T S
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCSFFNGKLVWDVGCGRR--HTVFLLGDGTVYTCGCNDLGQLGHEKTRK--KPEQVVALDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLS 208

HSP 5 Score: 91.2781 bits (225), Expect = 2.262e-17
Identity = 56/156 (35.90%), Postives = 85/156 (54.49%), Query Frame = 2

Query: 1544 INHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR-PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + H+    K + V+ L ++N ++ V      SH LA+ + GQV++WG  + G+LG  + +D  R P  I + S  H  + QV CG  HSL L++ G I+S G+N  GQLG G      L  ++  S L+G+   QI+  G  S  L+  GA+F WG
Sbjct:   66 LGHEKTRKKPEQVVALDAQN-IVAVSCG--ESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVH--IVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQS-LLGIPFAQISAGGAHSFGLTLSGAVFGWG 215

HSP 6 Score: 80.1073 bits (196), Expect = 6.017e-14
Identity = 95/329 (28.88%), Postives = 142/329 (43.16%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKT--NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELEN---LQIPYSVTAIDGKEVNLNIETSGAIFVNASNR----NSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVK-SDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDI 15103
            KV  +GE   D GG   E    I  EL +     F    +     L  +ADKT      F  +G + G+AI     + L     ++K L  ++   +DL+    D+  SL  L    E ++E    L    +V      EV   +     I VN  NR    N+Y+D + N  + +          G   V    +L LF   EL+ +V GN +     L+    Y+G   +    I  FWE+  E+  E +  FL F+ G  R+P     + G + +  V+      + YLP A+TCF LL LP Y+S+ ILQEKLL AI   +  ++
Sbjct:  731 KVIFVGEEAVDAGGVRKEFFLLIMKELLDPKYGMFRYYEESR---LIWFADKTFEEVDLFHLIGVICGLAIYNLTIVELNFPVALYKKLLKRTPTLDDLKELMPDVGRSLQQLLDYTEDDVEETFCLNFTITVENFGATEVLELVPNGMDINVNNHNRQDFVNAYVDYIFNTSVAQLFNA---FHAGFHKVCGGNVLELFQPNELQAMVIGNTNYDWKELEQSAEYKGEYWAGHPTIKLFWEVFHELPLEKKKQFLLFLTGSDRIP-----ILGMKSLALVIQPTGGGEHYLPVAHTCFNLLDLPKYNSRQILQEKLLKAIEHNQGFNL 1048

HSP 7 Score: 79.337 bits (194), Expect = 1.182e-13
Identity = 63/242 (26.03%), Postives = 110/242 (45.45%), Query Frame = 2

Query: 1295 HKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIID---TFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            H ++ +   T  T   NDL +   E    +P+++   L+ +  I  + C    T  L+D G ++    +S+  +         + +  DC++    +K  S+  ++ V       H LA++  GQ++SWG N  G+LG G    ++ P+++      S   +   Q++ G  HS  LT SG ++  GRN  GQLG  D  DR  P  +    L    V  I      +  L+ +G +FT+G+
Sbjct:   45 HTVFLLGDGTVYTCGCNDLGQLGHEKTRKKPEQV-VALDAQ-NIVAVSCGESHTLALNDKGQVFAWGQASEGQL--------GLANMEDCVRVPRNIKSLSEVHIVQVTCGY--RHSLALSRRGQIFSWGQNKYGQLGLG----KEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKT--LRSQRVVYICCGEDHTAALTKEGGVFTFGA 268

HSP 8 Score: 78.5666 bits (192), Expect = 1.757e-13
Identity = 64/205 (31.22%), Postives = 106/205 (51.71%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSK-IKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGST-ESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            +V++WG    GQLG       ++VP   + LS +   Q+  G +    +S  G++++ G    G+LG+G    SV TP LV  L    +    +++GG H   L  +G V+ WG  +  +LGL+       D   P L+K+L    ++ I  G  H+AA+++ G ++T+G G YG+LGH   + +  P+ V  L G  V  ++CG
Sbjct:  104 QVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLG--IPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLN----DNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCG 302

HSP 9 Score: 70.8626 bits (172), Expect = 4.604e-11
Identity = 39/126 (30.95%), Postives = 65/126 (51.59%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMC-LSNDGAIFTWG 2008
             +H   +T +G V+ WG N  G+LG  D  DR  P ++ T      +V  + CGE+H+  LT+ G +++ G    GQLGH        P ++   +L+G +V QI+     +M  + + G I ++G
Sbjct:  199 GAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRS--QRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVF--ELMGNVVTQISCGRQHTMAFIPSSGKIDSFG 320

HSP 10 Score: 63.929 bits (154), Expect = 5.776e-9
Identity = 48/171 (28.07%), Postives = 81/171 (47.37%), Query Frame = 2

Query: 1679 WGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL----QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-----EIDQIQVH-DSTYSVLL-KSGSVYTW 2158
            WG  + G+LG G   +     I+    +C       V  V CG  H++ L   G +Y+CG N +GQLGH   K R  P ++ A D   ++   ++     ++ L++ G +F WG   +  +  L+N    +E CV   RN     E+  +QV     +S+ L + G +++W
Sbjct:    4 WGNASYGQLGLGGIDEE----IVVEPRKCSFFNGKLVWDVGCGRRHTVFLLGDGTVYTCGCNDLGQLGH--EKTRKKPEQVVALDAQNIVA--VSCGESHTLALNDKGQVFAWGQASEG-QLGLAN----MEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSW 161

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Cavefish
Match: herc4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4 [Source:NCBI gene;Acc:103028096])

HSP 1 Score: 154.451 bits (389), Expect = 1.264e-36
Identity = 100/325 (30.77%), Postives = 169/325 (52.00%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDT--AMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXX-XXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD--LDSF 10552
            G++S G+LG+G    I  E+++ P++    +   +  V    G RH + L  +G  ++ G  D G+LGH    K   P ++     + +V V+CG SH+ A+   G ++ WG    G+LG  +    +R+ P  +KSL +  +VQV CG R   +LAL+    ++SWG   +G+LG G      L PQ ++ +      QI  G   SF LT +G V+ WG+  + +LG   +     P  ++ L+  ++V++  G  H  A+T  G V+++G   +GQ G+ T  + + P  V  LM N +  ++CG  H++A+  S   +DSF
Sbjct:    5 GNASYGQLGLGG---IDEEIVVEPRKCSFFNGKLVWDVGC--GRRHTVFLLGDGTVYTCGCNDLGQLGHEKTRK--KPEQVVALDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRV-PRNIKSLSEVHIVQVTCGYR--HSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSSGKIDSF 319

HSP 2 Score: 112.079 bits (279), Expect = 1.259e-23
Identity = 63/216 (29.17%), Postives = 111/216 (51.39%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSK-VKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +++ WG   + QLG       V++P   ++LSE+  V ++ G +    ++R G+++  G +  G+LG+G +       ++ P+ +++L    I    + +GG H+  LT +G  F WG    G+LG N       P  +K  + +RVV + CG  H+AA+   G ++T+G G YG+LGH  T   ++P  V  L    V Q++CG +       +S
Sbjct:  104 QVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKE----GPSVLTPQLVQSL--LGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSS 313

HSP 3 Score: 102.834 bits (255), Expect = 7.754e-21
Identity = 93/330 (28.18%), Postives = 160/330 (48.48%), Query Frame = 2

Query: 12614 GFGNNGRLGIGST--ESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKL-PMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            G  + G+LG+G    E V  P   S    K+V  V    G +H + L  +G VY  G  +  +LG +   +  E V+      +L    I+ ++ G SH+ A++  G+++ WG+   G+LG  N +D    P+ +++L   H++ V CG     +L +++             ++SWG   YG+LG G      L P  +++L G    ++  G   S  LT SG V+ WG+  + +LG   ++    P  +  L  ++++ + CG  H    T++G V+++G    GQLG  TT     PR +  L G  + +++CG  HT+A+   SG
Sbjct:    5 GNASYGQLGLGGIDEEIVVEPRKCSFFNGKLVWDVGC--GRRHTVFLLGDGTVYTCGCNDLGQLGHEKTRKKPEQVV------ALDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGY--RHSLALSRR----------GQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCGRQHTMAFIPSSG 314

HSP 4 Score: 100.908 bits (250), Expect = 2.711e-20
Identity = 68/212 (32.08%), Postives = 106/212 (50.00%), Query Frame = 2

Query: 9914 LYTWGLGDYGRLGHG--DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLG-HGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYN-MRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +  WG   YG+LG G  D  + + P          V  V CG R   T+ L  D TV++ G  D G+LG   +     P+++  +   N++ + CG   + AL + GQV+ WG+    +LG    +  +R P  I+ L +  IV +  G  H LA++ RGQ++SWG N +GQ G G    + + P LV +L+    A ++ G +HS   T S
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCSFFNGKLVWDVGCGRR--HTVFLLGDGTVYTCGCNDLGQLGHEKTRK--KPEQVVALDAQNIVAVSCGESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLS 208

HSP 5 Score: 91.2781 bits (225), Expect = 2.774e-17
Identity = 56/156 (35.90%), Postives = 85/156 (54.49%), Query Frame = 2

Query: 1544 INHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR-PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + H+    K + V+ L ++N ++ V      SH LA+ + GQV++WG  + G+LG  + +D  R P  I + S  H  + QV CG  HSL L++ G I+S G+N  GQLG G      L  ++  S L+G+   QI+  G  S  L+  GA+F WG
Sbjct:   66 LGHEKTRKKPEQVVALDAQN-IVAVSCG--ESHTLALNDKGQVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVH--IVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQS-LLGIPFAQISAGGAHSFGLTLSGAVFGWG 215

HSP 6 Score: 80.1073 bits (196), Expect = 6.401e-14
Identity = 95/329 (28.88%), Postives = 142/329 (43.16%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKT--NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELEN---LQIPYSVTAIDGKEVNLNIETSGAIFVNASNR----NSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVK-SDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDI 15103
            KV  +GE   D GG   E    I  EL +     F    +     L  +ADKT      F  +G + G+AI     + L     ++K L  ++   +DL+    D+  SL  L    E ++E    L    +V      EV   +     I VN  NR    N+Y+D + N  + +          G   V    +L LF   EL+ +V GN +     L+    Y+G   +    I  FWE+  E+  E +  FL F+ G  R+P     + G + +  V+      + YLP A+TCF LL LP Y+S+ ILQEKLL AI   +  ++
Sbjct:  719 KVIFVGEEAVDAGGVRKEFFLLIMKELLDPKYGMFRYYEESR---LIWFADKTFEEVDLFHLIGVICGLAIYNLTIVELNFPVALYKKLLKRTPTLDDLKELMPDVGRSLQQLLDYTEDDVEETFCLNFTITVENFGATEVLELVPNGMDINVNNHNRQDFVNAYVDYIFNTSVAQLFNA---FHAGFHKVCGGNVLELFQPNELQAMVIGNTNYDWKELEQSAEYKGEYWAGHPTIKLFWEVFHELPLEKKKQFLLFLTGSDRIP-----ILGMKSLALVIQPTGGGEHYLPVAHTCFNLLDLPKYNSRQILQEKLLKAIEHNQGFNL 1036

HSP 7 Score: 78.9518 bits (193), Expect = 1.403e-13
Identity = 63/242 (26.03%), Postives = 110/242 (45.45%), Query Frame = 2

Query: 1295 HKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIID---TFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            H ++ +   T  T   NDL +   E    +P+++   L+ +  I  + C    T  L+D G ++    +S+  +         + +  DC++    +K  S+  ++ V       H LA++  GQ++SWG N  G+LG G    ++ P+++      S   +   Q++ G  HS  LT SG ++  GRN  GQLG  D  DR  P  +    L    V  I      +  L+ +G +FT+G+
Sbjct:   45 HTVFLLGDGTVYTCGCNDLGQLGHEKTRKKPEQV-VALDAQ-NIVAVSCGESHTLALNDKGQVFAWGQASEGQL--------GLANMEDCVRVPRNIKSLSEVHIVQVTCGY--RHSLALSRRGQIFSWGQNKYGQLGLG----KEGPSVLTPQLVQSLLGIPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKT--LRSQRVVYICCGEDHTAALTKEGGVFTFGA 268

HSP 8 Score: 78.5666 bits (192), Expect = 1.967e-13
Identity = 64/205 (31.22%), Postives = 106/205 (51.71%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSK-IKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGST-ESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            +V++WG    GQLG       ++VP   + LS +   Q+  G +    +S  G++++ G    G+LG+G    SV TP LV  L    +    +++GG H   L  +G V+ WG  +  +LGL+       D   P L+K+L    ++ I  G  H+AA+++ G ++T+G G YG+LGH   + +  P+ V  L G  V  ++CG
Sbjct:  104 QVFAWGQASEGQLGLANMEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSWGQNKYGQLGLGKEGPSVLTPQLVQSLLG--IPFAQISAGGAHSFGLTLSGAVFGWGRNKFGQLGLN----DNSDRCAPCLLKTLRSQRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVFELMGNVVTQISCG 302

HSP 9 Score: 70.4774 bits (171), Expect = 5.564e-11
Identity = 48/172 (27.91%), Postives = 79/172 (45.93%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMC-LSNDGAIFTWG-------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYS 2125
             +H   +T +G V+ WG N  G+LG  D  DR  P ++ T      +V  + CGE+H+  LT+ G +++ G    GQLGH        P ++   +L+G +V QI+     +M  + + G I ++G        T   C R     SP       ++R   D I + +  Y+
Sbjct:  199 GAHSFGLTLSGAVFGWGRNKFGQLGLNDNSDRCAPCLLKTLRS--QRVVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNTTNHEINPRKVF--ELMGNVVTQISCGRQHTMAFIPSSGKIDSFGLGGNGQLGTRSTCNRK----SPA--PVKGQWRAYNDPIPMEEGQYT 360

HSP 10 Score: 63.5438 bits (153), Expect = 6.868e-9
Identity = 48/171 (28.07%), Postives = 81/171 (47.37%), Query Frame = 2

Query: 1679 WGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL----QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-----EIDQIQVH-DSTYSVLL-KSGSVYTW 2158
            WG  + G+LG G   +     I+    +C       V  V CG  H++ L   G +Y+CG N +GQLGH   K R  P ++ A D   ++   ++     ++ L++ G +F WG   +  +  L+N    +E CV   RN     E+  +QV     +S+ L + G +++W
Sbjct:    4 WGNASYGQLGLGGIDEE----IVVEPRKCSFFNGKLVWDVGCGRRHTVFLLGDGTVYTCGCNDLGQLGH--EKTRKKPEQVVALDAQNIVA--VSCGESHTLALNDKGQVFAWGQASEG-QLGLAN----MEDCVRVPRNIKSLSEVHIVQVTCGYRHSLALSRRGQIFSW 161

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Cavefish
Match: herc3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:NCBI gene;Acc:103047299])

HSP 1 Score: 150.214 bits (378), Expect = 2.849e-35
Identity = 96/318 (30.19%), Postives = 166/318 (52.20%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG--DTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXX-XXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            G S+ G+LG+G    + AE    P+         + +VA    G+H++ L  +G  +S G    G+LGH      N P  +     +++  VACG +HS A+   G ++ WG G+ G+LG G  + A+R+ P L+K L ++++ QV CG++    +AL  D  +++WG    G+LG G      L PQ ++ +    + QI  G   SFAL+ +G V+ WG+    +LG   ++    P  I+ L+  K+V+++ G  H  A+T  G ++++G+   GQ G+ +      P  V  LM  +++ + CG  H++A+  S
Sbjct:    5 GSSAWGQLGLGDAEPVVAE----PRSCRMFSGRGLKEVACR--GQHSLFLLHDGSVYSCGSNSHGQLGHEK--PGNKPELVVALDAQKIAGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRV-PRLIKKLCEHRISQVMCGNQ--HCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCGKHHTLAFVPS 311

HSP 2 Score: 137.887 bits (346), Expect = 1.539e-31
Identity = 112/366 (30.60%), Postives = 176/366 (48.09%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGC-EATSKVKLP-----ILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNS-RLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGD-TAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLA-VTDRGQVYSWGDNDHGQ-----QGNGTVTY---NMRPTLVSA 10471
            +  WG +   QLG  +A   V  P          L E+ C     G  SLF +   G VY  G +S+G+LG     +        P+ + ALD   I  VA   G  H++A+ + G+ F+WG G+ G+LG  +    +  PR IK     R+  V CG+ H  A+   G L+TWG    G+LG G      L P+ +KSL    + Q++ G   +  L+L+    V+ WG    G+LG        +P  I+ +    V+ I CG + + ALT++G ++T+G G   +LGH +  +   P ++ +L  T++  +  G  H LA V   G VY++G N HGQ     +GN  +     N++P  +S+
Sbjct:    1 MLCWGSSAWGQLGLGDAEPVVAEPRSCRMFSGRGLKEVAC----RGQHSLF-LLHDGSVYSCGSNSHGQLGHEKPGN-------KPELVVALDAQKIAGVAC--GDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSG--AVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCGKHHTLAFVPSTGLVYAFGCNAHGQLGLANRGNARIPLPVRNIQPPYLSS 350

HSP 3 Score: 123.635 bits (309), Expect = 3.196e-27
Identity = 108/344 (31.40%), Postives = 166/344 (48.26%), Query Frame = 2

Query: 12455 WGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQII-GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPF-PKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCIC-CTEDGEVYSWGDNDEGQLG 13474
            WG +  GQLG G     +  P  C   S    +++   G+ SLF++  DG VY+ G  ++G+LG    +    P LV  L+ + +  VA   G  H LA+   G V+AWG  E  +LGL       E V  P L+K L +  I  +  G  H  A+++ G+L+TWG+   G+LG G G+     P+ +++L         CG   AQ   I+   D    L  + +V+ WG    G+LG        +P  I+ L    V+ + CG + +  LT  G ++T+G G   +LGH S N+   P +V +L   ++  + CG  H +      G VY++G N  GQLG
Sbjct:    4 WGSSAWGQLGLGDAEPVVAEPRSCRMFSGRGLKEVACRGQHSLFLLH-DGSVYSCGSNSHGQLG--HEKPGNKPELVVALDAQKIAGVAC--GDAHSLAVNEQGQVFAWGTGEKGQLGLGTV---EEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSL---------CGIPLAQ---ISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCGKHHTLAFVPSTGLVYAFGCNAHGQLG 327

HSP 4 Score: 112.464 bits (280), Expect = 1.007e-23
Identity = 93/324 (28.70%), Postives = 162/324 (50.00%), Query Frame = 2

Query: 12629 GRLGIGSTESV-QTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQ-PFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKL-PMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            G+LG+G  E V   P        + + +VA    G+H L L ++G VY+ G     +LG +   +PG     P LV +L   +I  +A G +HS A++  G+++ WG G  G+LG G  ++    P++++ L  + +  V CG+      CI   +D ++        ++WG    G+LG G  +   L P  +++L G  + ++  G   S  L+ SG V+ WG+    +LG   +     P  +  L  +K++ ++CG  H    T+DG ++++G+   GQLG  +T     PR +  L G  ++++ CG  HTLA+   +G
Sbjct:   10 GQLGLGDAEPVVAEPRSCRMFSGRGLKEVACR--GQHSLFLLHDGSVYSCGSNSHGQLGHE---KPGNK---PELVVALDAQKIAGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQH----CIALAKDGQL--------FTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCGKHHTLAFVPSTG 313

HSP 5 Score: 112.079 bits (279), Expect = 1.068e-23
Identity = 65/215 (30.23%), Postives = 112/215 (52.09%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSK-VKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALT 10063
            +++ WG  +K QLG     + V++P L + L E     +  G++    + + G+++  G +S+G+LG+G     +    + P+ L++L    + +++  +GG H+ AL+ +G  F WG    G+LG N       P  IK+ + ++VV ++CG  H+AA+   G L+T+G G  G+LGH  T     P  V  L   +V Q+ CG     TLA  
Sbjct:  103 QVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSS----LSPQPLKSLCGIPLAQIS--AGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCGKH--HTLAFV 309

HSP 6 Score: 90.1225 bits (222), Expect = 6.017e-17
Identity = 65/205 (31.71%), Postives = 113/205 (55.12%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTE-SVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            +V++WG   +GQLG G     ++VP L + L   R  Q++ G Q    ++ DG+++  G  ++G+LG+G  E S  +P  +  L    + +++  +GG H  AL  +G V+ WG     +LGL+      +D   P  +K L   +++ I+ G  H+AA+++ G L+T+G G  G+LGH + +++P P+ V  L G  V  + CG
Sbjct:  103 QVFAWGTGEKGQLGLGTVEEAVRVPRLIKKLCEHRISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSLCGIPLAQIS--AGGDHSFALSLSGAVFGWGRNSAGQLGLNDE----QDRAVPCHIKFLRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCG 301

HSP 7 Score: 81.2629 bits (199), Expect = 2.707e-14
Identity = 57/211 (27.01%), Postives = 103/211 (48.82%), Query Frame = 2

Query: 1379 IRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMC-LSNDGAIFTWG 2008
            +R  +L ++L E  RI +++C       L+  G L+    +S   +     + ++++ Q         LK      +  + A     H  A++ +G V+ WG N++G+LG  D +DR  P  I  F R   +V  ++CG+EH+  LT+ G +++ G    GQLGH    +  LP R+   +L+G  V QI    H ++  + + G ++ +G
Sbjct:  124 VRVPRLIKKLCEH-RISQVMCGNQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQ--------PLKSLCGIPLAQISAG--GDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIK-FLRSQ-KVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVL--ELMGTEVSQIVCGKHHTLAFVPSTGLVYAFG 319

HSP 8 Score: 79.7221 bits (195), Expect = 7.640e-14
Identity = 61/249 (24.50%), Postives = 113/249 (45.38%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLS-NWSPKIETCVNEYRNEIDQIQV-HDSTYSVLLKSGSVYTW 2158
            +I  + C    +  +++ G ++   T     +   T +        + ++   ++K   ++R+  V     + H +A+ + GQ+++WG N+SG+LG G  +     P  + +   C + + Q++ G +HS  L+ SG ++  GRN  GQLG  D +DR +P  I    L    V  I+     +  L+ DG +FT+G+       H S N  P     +     E+ QI      T + +  +G VY +
Sbjct:   84 KIAGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVE--------EAVRVPRLIKKLCEHRISQVMCG--NQHCIALAKDGQLFTWGQNSSGQLGLGKGEPSSLSPQPLKSL--CGIPLAQISAGGDHSFALSLSGAVFGWGRNSAGQLGLNDEQDRAVPCHIKF--LRSQKVVYISCGDEHTAALTKDGGLFTFGNGSRGQLGHDSTNNEPLPRRVLELMGTEVSQIVCGKHHTLAFVPSTGLVYAF 318

HSP 9 Score: 70.4774 bits (171), Expect = 5.775e-11
Identity = 52/174 (29.89%), Postives = 82/174 (47.13%), Query Frame = 2

Query: 1679 WGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL----QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDR-HLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS---------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            WG++  G+LG GD +    P + +  S C +     +K+VAC  +HSL L   G +YSCG N  GQLGH    ++  L + + A  + GV       D H S+ ++  G +F WG+         T +   R      P++   + E+R  I Q+   +     L K G ++TW
Sbjct:    4 WGSSAWGQLGLGDAE----PVVAEPRS-CRMFSGRGLKEVACRGQHSLFLLHDGSVYSCGSNSHGQLGHEKPGNKPELVVALDAQKIAGVACG----DAH-SLAVNEQGQVFAWGTGEKGQLGLGTVEEAVR-----VPRLIKKLCEHR--ISQVMCGNQHCIALAKDGQLFTW 160

HSP 10 Score: 65.4698 bits (158), Expect = 1.799e-9
Identity = 38/123 (30.89%), Postives = 61/123 (49.59%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H L +   G VYS G+N+ G+LG    K   +P ++        ++  VACG+ HSL + + G +++ G    GQLG G V++     R+    L    + Q+       + L+ DG +FTWG
Sbjct:   44 HSLFLLHDGSVYSCGSNSHGQLGH--EKPGNKPELVVALDA--QKIAGVACGDAHSLAVNEQGQVFAWGTGEKGQLGLGTVEEAVRVPRLI-KKLCEHRISQVMCGNQHCIALAKDGQLFTWG 161

HSP 11 Score: 60.077 bits (144), Expect = 8.827e-8
Identity = 76/282 (26.95%), Postives = 119/282 (42.20%), Query Frame = 2

Query: 14291 YADK--TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDL------------QLFDKDXXXXXXXXKAIDETELENLQIP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHE-FDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRG-VKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            ++DK      WF  +G + G+AI  +  + L    +++K L   S + +DL            QL D +          I+ET   N  I    Y +T     EV   +     I V+ SNR  ++   + Y   +   +       G   V    +L+LF   EL  +V GN S     L+   +Y+G   +    +  FWE+  +   E +  FL F+ G  R+P     + G   +  VL   S A+ YLP A+TC+ LL +P Y +K  L  +L  AI
Sbjct:  820 FSDKCFVEHNWFNLIGIVCGLAIYNSTVVDLHFPLVLYKKLLDVSPSLDDLKELSPTEGRSLQQLLDYEG-------DDIEETFCLNFAITREHYGMT-----EVKELVPGGENITVDRSNREEFVQAYLRYVFSDSVQELYSAFSGGFLKVCGGRILSLFQPSELMAMVVGNSSYNWEELEKNAVYKGEFSASHPTVRMFWEVFHDFPLEKKKQFLLFLTGSDRIP-----IHGMASLRIVLQSTSAAEHYLPVAHTCYNLLDMPCYKTKETLHLRLTRAI 1084

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001275.1 (pep scaffold:Pmarinus_7.0:GL476529:184068:212443:-1 gene:ENSPMAG00000001140.1 transcript:ENSPMAT00000001275.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 219.164 bits (557), Expect = 3.134e-57
Identity = 148/380 (38.95%), Postives = 209/380 (55.00%), Query Frame = 2

Query: 9419 SKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIK-YFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDF-TVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            S++YVWG N   QL   A  K+  P +    +  +  +I  G    F +   G V   G  S GRLG+G   + +       K+L    +  + K++   G   H +A+T  GE FSWG+GD GKLGH +     YP+ I+   +GK VV V+ G  HSA++   G LYTWG GD+GRLGHGD+  R  P LVK + +  V QVACGS  + T+A++ D   VWS+G GD GKLG G ++    P+ IE +    + ++  G+QSS ALT  GQ++ WG G     G      +R P  IEDL  T+IV ++ G  HCLA+T   +VY+WG+N  GQ G G  T  + +P  V  +    +  ++ G+SHS+AWTA   D
Sbjct:  379 SEVYVWGSNSSHQLAEGAQEKILQPKMASGFA--NAQTIEAGQYCTFVIAVDGSVRACGKGSYGRLGLGDSNNQSTL-----KKLTFEPQRAVKKISSSRGSDGHTLAVTMEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSASVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGQVACGS--SHTIAVSQDGRIVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQLYAWGCGACLGCGSSEATALR-PKLIEDLACTRIVDISCGDSHCLALTHDNEVYAWGNNSMGQCGQGHSTSPVTKPKKVMGMDGISVQQISAGTSHSLAWTALPTD 746

HSP 2 Score: 182.185 bits (461), Expect = 9.792e-46
Identity = 133/388 (34.28%), Postives = 216/388 (55.67%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXX-XXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTVSGNK 13597
            EV+ WG N   QL      KI  P +    +    + I  G+   F++++DG V A G G+ GRLG+G + +  T   ++   ++ V K++ + G   H LA+   G V++WGD +  KLG             P L++  ++ +++  ++AG  HSA+++  GELYTWG+G +GRLGHG+ + +  P +V+ +   +V  VACGS       I  ++D RI       VWS+G GD GKLG G  +    P  IE L+G  + KV  GSQ SL LT++G++Y WG G     G  S+    +P+ +  L   +I+D++CG  HC+  T D EVY+WG+N  GQ G G +T+  ++P+ +  + G  + +++ G++H+LAWT +  ++
Sbjct:  380 EVYVWGSNSSHQLAEGAQEKILQPKMASGFA--NAQTIEAGQYCTFVIAVDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPQRAVKKISSSRGSDGHTLAVTMEGEVFSWGDGDYGKLGHG----NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSASVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS--NVGQVACGSSHT----IAVSQDGRI-------VWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQLYAWGCGACLGCG-SSEATALRPKLIEDLACTRIVDISCGDSHCLALTHDNEVYAWGNNSMGQCGQGHSTSPVTKPKKVMGMDGISVQQISAGTSHSLAWTALPTDR 747

HSP 3 Score: 87.4261 bits (215), Expect = 7.298e-17
Identity = 45/124 (36.29%), Postives = 70/124 (56.45%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDI-YSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H  +VTE G++Y+WG    G+LG GD+  R  PT++   S     V QVACG  H++ ++Q G I +S G    G+LGHGD    + P  I A  L G+ ++++      S+ L++ G ++ WG
Sbjct:  529 HSASVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDIS----NVGQVACGSSHTIAVSQDGRIVWSFGGGDNGKLGHGDTNRVYKPKVIEA--LQGMFIRKVCAGSQSSLALTSTGQLYAWG 646

HSP 4 Score: 81.6481 bits (200), Expect = 4.848e-15
Identity = 61/202 (30.20%), Postives = 95/202 (47.03%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC---GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSN----WSPK-IETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW-LKYCTECNKSD--DIQPEL 2209
             H LAVT  G+V+SWG    GKLG G++  +K P +I    +  LQ K V C   G  HS  +T+ G++Y+ G    G+LGHGD   R++P  +     +G    Q+A     ++ +S DG I       DN +    +    + PK IE     +   I ++     +   L  +G +Y W    C  C  S+   ++P+L
Sbjct:  475 GHTLAVTMEGEVFSWGDGDYGKLGHGNSSTQKYPKLI----QGPLQGKVVVCVSAGYRHSASVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVG----QVACGSSHTIAVSQDGRIVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMF---IRKVCAGSQSSLALTSTGQLYAWGCGACLGCGSSEATALRPKL 665

HSP 5 Score: 68.5514 bits (166), Expect = 4.745e-11
Identity = 87/310 (28.06%), Postives = 147/310 (47.42%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQII---GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNG-LVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPF-PKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXX--XXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTA---SGEVYTWGKGDYFRLGHGSDNHVR 13342
            EV+SWG    G+LG    S  K P L +    L+ + ++    G +    V+ DG +Y  G G+ GRLG G + S   P LV  +    V +VA   G  H +A+  +G +V+++G  ++ KLG          V  P ++++L    I  + AG   S A++ +G+LY WG G    LG G+ +     PK++E L    ++ ++C  GD+  L +T + +          V++WG+   G+   G     + K P K+  ++G  V ++  G+  SL  TA     +V  W +     L   + +H+R
Sbjct:  485 EVFSWGDGDYGKLGHGNSSTQKYPKLIQ--GPLQGKVVVCVSAGYRHSASVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISN--VGQVAC--GSSHTIAVSQDGRIVWSFGGGDNGKLGHGDT----NRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQLYAWGCGAC--LGCGSSEATALRPKLIEDLACTRIVDISC--GDSHCLALTHDNE----------VYAWGNNSMGQCGQGHSTSPVTK-PKKVMGMDGISVQQISAGTSHSLAWTALPTDRQVVAWHRPFCVDLEESTFSHLR 769

HSP 6 Score: 58.151 bits (139), Expect = 6.669e-8
Identity = 50/179 (27.93%), Postives = 82/179 (45.81%), Query Frame = 2

Query: 1598 KNRVIDVDANIY-------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHG-DVKDRHLPIRITASDLIGVLVKQIAVDGHQSM---CLSNDGAIFTW---------GSTFDNCRRHLSNWSPKIETCV 2071
            K +VI+    ++       S   LA+T  GQ+Y+WG      LG G ++    RP +I+  + C  ++  ++CG+ H L LT   ++Y+ G N MGQ G G        P ++   D  G+ V+QI+     S+    L  D  +  W          STF + R  L ++  +I + V
Sbjct:  611 KPKVIEALQGMFIRKVCAGSQSSLALTSTGQLYAWGCGAC--LGCGSSEATALRPKLIEDLA-C-TRIVDISCGDSHCLALTHDNEVYAWGNNSMGQCGQGHSTSPVTKPKKVMGMD--GISVQQISAGTSHSLAWTALPTDRQVVAWHRPFCVDLEESTFSHLRSFLEHYYDRINSDV 783

HSP 7 Score: 55.4546 bits (132), Expect = 4.320e-7
Identity = 30/121 (24.79%), Postives = 62/121 (51.24%), Query Frame = 2

Query: 1652 VTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGV--LVKQIAVDGHQSMCLSNDGAIFTWG 2008
            V+E  +VY WG+N+S +L +G  +   +P +   F+      + +  G+  + ++   G + +CG+   G+LG GD  ++    ++T      V  +      DGH ++ ++ +G +F+WG
Sbjct:  375 VSETSEVYVWGSNSSHQLAEGAQEKILQPKMASGFA----NAQTIEAGQYCTFVIAVDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPQRAVKKISSSRGSDGH-TLAVTMEGEVFSWG 490

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Sea Lamprey
Match: rcc2 (regulator of chromosome condensation 2 [Source:NCBI gene;Acc:406455])

HSP 1 Score: 119.783 bits (299), Expect = 3.836e-28
Identity = 100/342 (29.24%), Postives = 163/342 (47.66%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNS---------RLKLN---YPRKIKYF------------KGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGK-GDYYRLGHGTDKHIREPMQIEDLKKTKIVHL---AVGALHCL 10366
            +Y WG  +K QLG   T +V +P + + L E   V  + G     C+T TG VY  G++  G+LG+G+ TD     +  P ++    +  +VKVA   G   ++ +  +G  FS+G  + G+LGHN+         R++      PR++  F            +G  V DVACG++H+ A+   G ++TWG G YGRLGH +    L P LVK L        +  +  + T A+    T++ WG  +  +         + P+ +  +  ++V  + CG +SS  +T +    +WG    Y  LG+G  K  R     ++LKK   +H+   A+G  H L
Sbjct:   75 VYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTD----AVPSPTQIVYSGRQ-VVKVAC--GAEFSVFIDCDGNLFSFGCPEYGQLGHNTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDTRGRVFTWGFGGYGRLGHAEQKDELLPRLVKLLDRPAPAVNSVRAGYSCTFAINVVGTLYFWGSTNTSRDPT------MYPKAVHDLCGTHVRSLACG-KSSILITSDESTMSWGPWPTYGELGYGEGKQ-RSSSMPQELKKLSGIHIHEVAMGFAHSL 401

HSP 2 Score: 101.679 bits (252), Expect = 3.720e-22
Identity = 92/343 (26.82%), Postives = 152/343 (44.31%), Query Frame = 2

Query: 9662 PKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDT--AMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLI-PQKIE---------------------CMSLSNVI--QIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREP--MQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYS 10606
            P R  +L    + +V       H++ ++  G  +SWG G+ G+LGH    +++ PR I   K   +VD ACG SH+  +   G +Y +G    G+LG G+   A+    ++V S R  +VV+VACG+    ++ +  D  ++S+G  ++G+LG       ++  Q+IE                      +++  V+   + CGA  + AL   G+V+TWG G Y RLGH   K    P  +++ D     +  +  G     A+   G +Y WG        N +    M P  V  L    +  +ACG S  +  +     S+ P      WP   E+ Y 
Sbjct:   43 PHRYGSLRDIAVSRVITGPCAAHSLLISTRGLVYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTDAVPSPTQIVYSGR--QVVKVACGAE--FSVFIDCDGNLFSFGCPEYGQLGHNTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDTRGRVFTWGFGGYGRLGHAEQKDELLPRLVKLLDRPAPAVNSVRAGYSCTFAINVVGTLYFWGST------NTSRDPTMYPKAVHDLCGTHVRSLACGKSSILITSDESTMSWGP------WPTYGELGYG 369

HSP 3 Score: 79.337 bits (194), Expect = 7.830e-15
Identity = 53/149 (35.57%), Postives = 75/149 (50.34%), Query Frame = 2

Query: 1589 LWSKNR--------VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDR-HLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            LW+ +R        V  V     ++H L ++  G VYSWG    G+LG GDT     P IIDT   C   +   ACG  H+L LT +G +Y+ G N +GQLG G+  D    P +I  S   G  V ++A     S+ +  DG +F++G
Sbjct:   40 LWAPHRYGSLRDIAVSRVITGPCAAHSLLISTRGLVYSWGRGEKGQLGHGDTCRVDVPRIIDTLKEC--VIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTDAVPSPTQIVYS---GRQVVKVACGAEFSVFIDCDGNLFSFG 183

HSP 4 Score: 77.0258 bits (188), Expect = 3.499e-14
Identity = 47/131 (35.88%), Postives = 73/131 (55.73%), Query Frame = 2

Query: 13190 PMKIETLEGAGVIKVDCG--SQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTT--TNSRPRIIESLTGKGINRVACGSAHTL 13570
            P +  +L    V +V  G  +  SL+++  G VY+WG+G+  +LGHG    V  P  +  L    I+D ACG  H +C T+ G VY++G+N  GQLG G  T    S  +I+ S  G+ + +VACG+  ++
Sbjct:   43 PHRYGSLRDIAVSRVITGPCAAHSLLISTRGLVYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTDAVPSPTQIVYS--GRQVVKVACGAEFSV 171

HSP 5 Score: 76.2554 bits (186), Expect = 7.036e-14
Identity = 94/337 (27.89%), Postives = 136/337 (40.36%), Query Frame = 2

Query: 12578 FIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLV----KSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNR--KKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTL 13570
             ++S  G VY+ G G  G+LG G T  V  P ++  L+E ++V  A   G  H L L + G VYA+G+    +LGL  +    + V +PT +    + +VK      A G   S  I   G L+++G   YG+LGH N D +    IV A R   V  +A          I K  D                                  ++ T+ G  V  V CG+  ++ L   G V+TWG G Y RLGH        P  V  L+R    +  V  G          G +Y WG  +  +  D T      P+ +  L G  +  +ACG +  L
Sbjct:   67 LLISTRGLVYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVIVDGAC--GRSHTLCLTDTGTVYAFGENRLGQLGLGNQT---DAVPSPTQIVYSGRQVVKV-----ACGAEFSVFIDCDGNLFSFGCPEYGQLGH-NTDGR---YIVRAQRIEFVCELA---PRRLARFIEKTRDG---------------------------------QVLTVRGVVVRDVACGANHTIALDTRGRVFTWGFGGYGRLGHAEQKDELLPRLVKLLDRPAPAVNSVRAGYSCTFAINVVGTLYFWGSTNTSR--DPTMY----PKAVHDLCGTHVRSLACGKSSIL 347

HSP 6 Score: 66.6254 bits (161), Expect = 7.946e-11
Identity = 52/165 (31.52%), Postives = 76/165 (46.06%), Query Frame = 2

Query: 1604 RVID-------VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDR-KRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHG----------------DVKDRHLPIRITAS------DLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            R+ID       VD     SH L +T+ G VY++G N  G+LG G+  D    PT I    R   QV +VACG E S+ +   G+++S G    GQLGH                 ++  R L   I  +       + GV+V+ +A   + ++ L   G +FTWG
Sbjct:   98 RIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTDAVPSPTQIVYSGR---QVVKVACGAEFSVFIDCDGNLFSFGCPEYGQLGHNTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDTRGRVFTWG 259

HSP 7 Score: 65.0846 bits (157), Expect = 2.515e-10
Identity = 94/360 (26.11%), Postives = 151/360 (41.94%), Query Frame = 2

Query: 12428 SASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGS-TESVQTP--ILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLD------IRVQPGEDV--LTPTLVKSLVKAEXXXXXXX------------XXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGK-GDYFRLGHGSDNHVRK--PEKVAQLNRKKIIDVACGSLHCICCTED 13429
            S  GL V+SWG   +GQLG  +  ++ VP + + L          G      ++  G VYA G    G+LG+G+ T++V +P  I+ SG +   VVKVA   G +  + +  +G ++++G  E  +LG +      +R Q  E V  L P  +   ++                      +H+ A+   G ++TWG G YGRLGH    D+  P++V+ L        A  S  A   C        I++V     W               D    P  +  L G  V  + CG   S+++T+     +WG    Y  LG+G         P+++ +L+   I +VA G  H +    D
Sbjct:   70 STRGL-VYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTDAVPSPTQIVYSGRQ---VVKVAC--GAEFSVFIDCDGNLFSFGCPEYGQLGHNTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDTRGRVFTWGFGGYGRLGHAEQKDELLPRLVKLL---DRPAPAVNSVRAGYSCTFA-----INVVGTLYFWG--------STNTSRDPTMYPKAVHDLCGTHVRSLACGKS-SILITSDESTMSWGPWPTYGELGYGEGKQRSSSMPQELKKLSGIHIHEVAMGFAHSLLLARD 406

HSP 8 Score: 56.6102 bits (135), Expect = 1.200e-7
Identity = 56/178 (31.46%), Postives = 88/178 (49.44%), Query Frame = 2

Query: 13124 VWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSD-NHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLG---DGTTTTNSR-------------PRIIES------LTGKG--INRVACGSAHTLAWTT 13582
            V+SWG G+ G+LG G      +P  I+TL+   ++   CG   +L LT +G VY +G+    +LG G+  + V  P ++    R +++ VACG+   +    DG ++S+G  + GQLG   DG     ++              R IE       LT +G  +  VACG+ HT+A  T
Sbjct:   75 VYSWGRGEKGQLGHGDTCRVDVPRIIDTLKECVIVDGACGRSHTLCLTDTGTVYAFGENRLGQLGLGNQTDAVPSPTQIVYSGR-QVVKVACGAEFSVFIDCDGNLFSFGCPEYGQLGHNTDGRYIVRAQRIEFVCELAPRRLARFIEKTRDGQVLTVRGVVVRDVACGANHTIALDT 251

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005516.1 (pep scaffold:Pmarinus_7.0:GL477585:22018:44632:1 gene:ENSPMAG00000004971.1 transcript:ENSPMAT00000005516.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 117.857 bits (294), Expect = 3.005e-26
Identity = 98/340 (28.82%), Postives = 162/340 (47.65%), Query Frame = 2

Query: 14144 WKVKLIGESVDDCGGGYSESITEICDELQNGH------LPFFI-----SSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFD----KDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNA--SNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVL--SKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDID 15106
            W      E ++D GGG  E +++I +EL          +PFF+     S+  ++  V  P  D  +   F ++G ++G A+R    L L +  L+WK L G+++  +D +  D    + L S   +       +L   ++ Y+ T   G+ V L     G ++V     +R  Y   V   ++ E  +    IR+GI  V+P  ++NL + +E+E +V G   I +  LK  ++   + + +  +   +E +   +NE R LFLRFV GR+R P            IQV+  S  S   D LPE   C   L LPNYSS  + +EKL +A++ C ++D D
Sbjct:  513 WSCDFTLEGMNDAGGGQRECLSDIAEELCPSDPYCPVPVPFFLRMLGRSTGGQESCVYVPNPDCRDLYMFTWIGKIMGAALRGANILILCLPALVWKQLVGETVTWSDFRSVDETLARSLRSLEEAADEAAFAQLFGEELTYATTLSSGRTVEL---VPGGVWVRVHYGDRLRYARLVQEARLCESRQQVEAIRKGIFSVVPQHIVNLLTWQEMERIVSGEAEITMDVLKR-SITSVMDNGEARMKCLFEALSNFSNEDRRLFLRFVTGRSRPP----------ITIQVMQSSMDSNKSDVLPETSLCSNTLILPNYSSAKVCEEKLHFAMYNCTTVDRD 838

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001750.1 (pep scaffold:Pmarinus_7.0:GL481695:1137:12922:1 gene:ENSPMAG00000001576.1 transcript:ENSPMAT00000001750.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.842 bits (268), Expect = 1.854e-23
Identity = 91/314 (28.98%), Postives = 146/314 (46.50%), Query Frame = 2

Query: 9656 IGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNS---RLKLNYPRKIKYF----KGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYY------RLGHGTDKH-----------IREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
            + P +L A+    +++VAV  G      +T++G    W E   G +G  +    +    P+ +  F     G  +  V+CG   +A +   G L T+G G  G LGHG  +    P++V++L  Y++ Q++CG   +  LA++++  V++WG GD G+LG G     L PQ +            CG   S  +T +G++   G    Y      ++ H  D             +  P+Q   L   ++VH+A+G  H  AVTD G  Y++G N HGQ G G  T +  P  V  L   K+  V CG + +VA
Sbjct:  244 LAPVKL-AMPNTEVLQVAV--GRTQRAGVTRSGRLIVW-EASPGTVGDAALPGSVGSVQPQLVSRFLEGQSGVTIQHVSCGDLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGM--SHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGIDCSM-VTSSGKLLACGSNRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVA 550

HSP 2 Score: 102.834 bits (255), Expect = 6.202e-22
Identity = 90/355 (25.35%), Postives = 152/355 (42.82%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLG----IGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACG------SRDAQTLALTSDF--------TVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQG 10426
            +S +Y+WG            + VKL     A+   + + ++ G      VTR+G++ V  ++S G +G     GS   +  +++   + LE      I  V+   G      LT  G   ++G G  G LGH S   +  P+ ++   G  +  ++CG SH  A+     ++ WG GD GRLG G+  + L P+ V     Y+     CG      +   + LA  S+          +   GD       +   S  L P +   +  + V+ +  G   S A+T+ G  +T+G   + +LG G     R P  ++ L   K+V +  G    +AV + GQV++WG    G+ G
Sbjct:  233 LSSVYMWGSG--------TLAPVKL-----AMPNTEVLQVAVGRTQRAGVTRSGRLIVW-EASPGTVGDAALPGSVGSVQPQLVS--RFLEGQSGVTIQHVSC--GDLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGIDCSMVTSSGKLLACGSNRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAVAEGGQVFTWGKAARGRLG 569

HSP 3 Score: 87.0409 bits (214), Expect = 6.292e-17
Identity = 72/231 (31.17%), Postives = 112/231 (48.48%), Query Frame = 2

Query: 12932 LYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGD-YFRLG-----HGSDNH-----------VRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            L T+G G  G LGHG+  D   PKIVEAL GY +  ++CG   +  L ++  ++          V++WG GD G+LG G  ++   P  +            CG   S+V T+SG++   G    Y +LG     H  D+            V  P + + L+  +++ VA G+ H    T+ G  Y++G N  GQLG G  T++  P+ ++ L G  + +V CG A T+A
Sbjct:  333 LMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGM--SHVLAVSNEQE----------VFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGIDCSMV-TSSGKLLACGSNRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVA 550

HSP 4 Score: 86.6557 bits (213), Expect = 8.008e-17
Identity = 85/314 (27.07%), Postives = 134/314 (42.68%), Query Frame = 2

Query: 12596 GRVYATGFGNNGRLGI--------------GSTESVQTPILVSGLEEKIVVKVA-VNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG------SGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLG 13474
            GR    G   +GRL +              GS  SVQ  ++   LE +  V +  V+ G      L + G++  +G      LG         DV  P +V++L+  EI  ++ G SH  A+S   E++ WG+G  GRLG GN +    P+ V     Y      CG      +   + L    N   R + +    +   GD       +    +   P++   L+GA V+ V  G+  S  +T +G  YT+G   + +LG G+    R P+ V  L   K++ V CG    +   E G+V++WG    G+LG
Sbjct:  262 GRTQRAGVTRSGRLIVWEASPGTVGDAALPGSVGSVQPQLVSRFLEGQSGVTIQHVSCGDLFTACLTDRGILMTYGSGSSGCLGHGSY----SDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGIDCSMVTSSGKLLACGSNR--RYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAVAEGGQVFTWGKAARGRLG 569

HSP 5 Score: 77.0258 bits (188), Expect = 6.565e-14
Identity = 61/223 (27.35%), Postives = 96/223 (43.05%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLG--------CEATSKVKLPILN-EALSELDCVSISGGSKSLFCVT--RTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGD-TAMRLHPELVKSLRDYKVVQVACGSRDAQTL 10054
            +++ WG  D  +LG        C     V  P     A   +DC  ++   K L C +  R  K+ +   S +G             +++ P +   LD   +V VA+  G  H+ A+T  G  +++G    G+LG  +R     P+ +    G +VV V CG + + A+  GG ++TWG    GRLG  D  A    P  ++    Y V  V+  SR   TL
Sbjct:  384 EVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGIDCSMVTSSGKLLACGSNRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVAL--GTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAVAEGGQVFTWGKAARGRLGRTDGEACVPGPVQLQERFPYAVTSVS--SRHGNTL 602

HSP 6 Score: 67.0106 bits (162), Expect = 8.227e-11
Identity = 50/187 (26.74%), Postives = 86/187 (45.99%), Query Frame = 2

Query: 9995 SLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKI----ECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDL 10543
            ++ + +V+QVA G      +  +    VW    G  G     GS G + PQ +    E  S   +  + CG   +  LT+ G + T+G G    LGHG+   + +P  +E L   +I  ++ G  H LAV++  +V++WG  D+G+ G G    ++ P  V+     +     CG   S+  ++  L
Sbjct:  250 AMPNTEVLQVAVGRTQRAGVTRSGRLIVWEASPGTVGDAALPGSVGSVQPQLVSRFLEGQSGVTIQHVSCGDLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGIDCSMVTSSGKL 436

HSP 7 Score: 65.4698 bits (158), Expect = 2.765e-10
Identity = 35/105 (33.33%), Postives = 55/105 (52.38%), Query Frame = 2

Query: 13199 IETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRII 13513
            +E   G  +  V CG  F+  LT  G + T+G G    LGHGS + V +P+ V  L   +I  ++CG  H +  + + EV++WG  D G+LG G    +  P+ +
Sbjct:  306 LEGQSGVTIQHVSCGDLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPV 410

HSP 8 Score: 62.3882 bits (150), Expect = 2.696e-9
Identity = 68/229 (29.69%), Postives = 107/229 (46.72%), Query Frame = 2

Query: 12446 VWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTE--SVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWG-DAEDNKLGLDIRVQPGED------------VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKN 13087
            + ++G    G LG    S +  P + E L      Q+  G   +  VS +  V+A G G+NGRLG+G+ E      P+ V    E       ++     C  + ++G + A G +   NKLGLD     G+D            VL+P     L  A ++ +A G +HSAA++ +G  YT+G  ++G+LG G       P+ V+ L G  V+ V C  GDA T+ + + 
Sbjct:  333 LMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGID-----CSMVTSSGKLLACGSNRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTC--GDAFTVAVAEG 554

HSP 9 Score: 56.9954 bits (136), Expect = 9.903e-8
Identity = 69/282 (24.47%), Postives = 116/282 (41.13%), Query Frame = 2

Query: 9761 FSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTW--GLGDYGRLGHGDTAMRLHPELVKSLRDYK----VVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDK-HI-REPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDND-HGQQGNGTVTYN----------------MRPTLVSALMDNKIAHVACGSSHSVAWT 10531
            + WG G        + +KL  P          V+ VA G +  A +   G L  W    G  G      +   + P+LV    + +    +  V+CG  D  T  LT    + ++G G  G LG G  S    P+ +E +    + Q+ CG     A++   +V+ WG+GD  RLG G  + H+  +P+ +    +    H  +    C  VT  G++ + G N  + + G   ++++                + P   S L   ++ HVA G++HS A T
Sbjct:  237 YMWGSGT------LAPVKLAMPNT-------EVLQVAVGRTQRAGVTRSGRLIVWEASPGTVGDAALPGSVGSVQPQLVSRFLEGQSGVTIQHVSCG--DLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAHCGI---DCSMVTSSGKLLACGSNRRYNKLGLDKISHDGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVT 500

HSP 10 Score: 56.225 bits (134), Expect = 2.077e-7
Identity = 28/92 (30.43%), Postives = 51/92 (55.43%), Query Frame = 2

Query: 1604 RVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGD 1879
            RV+ V   + ++H  AVT+ G  Y++G+N  G+LG G     + P  +D      ++V QV CG+  ++ + + G +++ G+   G+LG  D
Sbjct:  485 RVVHV--ALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLG--GVKVVQVTCGDAFTVAVAEGGQVFTWGKAARGRLGRTD 572

HSP 11 Score: 53.1434 bits (126), Expect = 1.508e-6
Identity = 24/65 (36.92%), Postives = 40/65 (61.54%), Query Frame = 2

Query: 13379 IIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            I  V+CG L   C T+ G + ++G    G LG G+ +  ++P+I+E+L G  I +++CG +H LA
Sbjct:  314 IQHVSCGDLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQMSCGMSHVLA 378

HSP 12 Score: 50.8322 bits (120), Expect = 7.918e-6
Identity = 60/287 (20.91%), Postives = 113/287 (39.37%), Query Frame = 2

Query: 1370 IVEIRPDKLPR--ELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRP---TIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNH------MGQLGHGDVKDRHLPIRITASDLI----------GVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-EIDQIQVHDSTYSVLLKSGSVYTWLK 2164
            +  ++P  + R  E      I+ + C  + T  L+D G L    + S   +   ++   A     + L    + ++           +   SHVLAV+   +V++WG   +G+LG G+ +    P    +   +  C        CG + S++ T SG + +CG N       + ++ H D  D   P   T   L+          G  V  +A+    S  +++ G  +T+GS         +  S +    V+     ++ Q+   D+    + + G V+TW K
Sbjct:  294 VGSVQPQLVSRFLEGQSGVTIQHVSCGDLFTACLTDRGILMTYGSGSSGCLGHGSYSDVAQPKIVEALLGYEITQM-----------SCGMSHVLAVSNEQEVFAWGRGDNGRLGLGNQELHLCPQPVAVPPPYEPCTAH-----CGIDCSMV-TSSGKLLACGSNRRYNKLGLDKISH-DGDDAACPAEQTEESLVLSPVQSSPLDGARVVHVALGTAHSAAVTDTGTCYTFGSNQHGQLGGGARTSSRAPQPVDGLGGVKVVQVTCGDAFTVAVAEGGQVFTWGK 562

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Sea Lamprey
Match: rcc2 (regulator of chromosome condensation 2 [Source:NCBI gene;Acc:406455])

HSP 1 Score: 95.9005 bits (237), Expect = 3.347e-20
Identity = 93/379 (24.54%), Postives = 148/379 (39.05%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNS---------RLKLN---YPRKIKYFKGKR------------VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDND--------HGQQGNGTVTYNMRP 10456
            + ++Y WG  DK QLG     +V+ P   +AL +L  V+ + G     C+T TG V   G++  G+LG+G+ ++        PK++       +VKVA   G   ++ +   G  +S+G  + G+LGHN+         RL+      PR++  F  +             V D+ACGS+H+        +++WG G YGRLGH +    + P LVK                        DF                       P +           +  G   SFA+ E G ++ WG     R      +    P  + DL   KI  LA G    +   D   + SWG +          G+Q + T+   ++P
Sbjct:   72 LGQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAACGRSHTLCITETGVVMAFGENHLGQLGLGTKSNAMPT----PKQI-VYSGQPVVKVAC--GAEFSMLVDCKGNLYSFGCPEYGQLGHNTDGRFLACSNRLEFVCELAPRRVLVFTERTRDGKVNTVPAVCVTDIACGSNHTLVRDSQRRVFSWGFGGYGRLGHSEQKDEMLPRLVKMF----------------------DF-----------------------PGR-------GAASVHAGYSCSFAIIETGALYFWGTSSTMR------ESTMYPKPVMDLAGWKIRSLACGKSSVMVAADESTI-SWGPSPAFGEIGYGDGKQKSSTIAKEVKP 384

HSP 2 Score: 94.3597 bits (233), Expect = 1.017e-19
Identity = 93/365 (25.48%), Postives = 148/365 (40.55%), Query Frame = 2

Query: 9506 ALSELDCVSISGGSKSLFCV--TRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRL-KLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRL----HPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREP--MQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALN 10573
             L+++   S+  G  +  C+  T  G+VY  G    G+LG G    + A     P+ ++AL K  +V  A   G  H + +T+ G   ++GE   G+LG  ++   +  P++I Y  G+ VV VACG+  S  +   G+LY++G  +YG+LGH      L      E V  L   +V+     +RD                                   K+  +    V  I CG+  +       +V++WG G Y RLGH   K    P  +++ D        +  G     A+ + G +Y WG +   ++        M P  V  L   KI  +ACG S  +        S+ PS A  
Sbjct:   48 CLAKVHVSSVVSGPTACHCLLLTDLGQVYTWGRGDKGQLGHGDLKRVEA-----PRPVDALFKLTVVAAAC--GRSHTLCITETGVVMAFGENHLGQLGLGTKSNAMPTPKQIVY-SGQPVVKVACGAEFSMLVDCKGNLYSFGCPEYGQLGHNTDGRFLACSNRLEFVCELAPRRVLVFTERTRDG----------------------------------KVNTVPAVCVTDIACGSNHTLVRDSQRRVFSWGFGGYGRLGHSEQKDEMLPRLVKMFDFPGRGAASVHAGYSCSFAIIETGALYFWGTSSTMRES------TMYPKPVMDLAGWKIRSLACGKSSVMVAADESTISWGPSPAFG 364

HSP 3 Score: 84.3445 bits (207), Expect = 1.784e-16
Identity = 66/242 (27.27%), Postives = 109/242 (45.04%), Query Frame = 2

Query: 12929 ELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETL-EGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHV----RKPEKVAQLNRKKII--------------------DVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIE--SLTGKGINRVACGSAHTLA 13573
            ++YTWG+G  G+LGHG+      P+ V+AL    V+  ACG   + TLCIT+           T V      ++      G     +P   + +  G  V+KV CG++FS+++   G +Y++G  +Y +LGH +D        + E V +L  ++++                    D+ACGS H +       V+SWG    G+LG         PR+++     G+G   V  G + + A
Sbjct:   74 QVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAACGR--SHTLCITE-----------TGVVMAFGENHLGQLGLGTKSNAMPTPKQIVYSGQPVVKVACGAEFSMLVDCKGNLYSFGCPEYGQLGHNTDGRFLACSNRLEFVCELAPRRVLVFTERTRDGKVNTVPAVCVTDIACGSNHTLVRDSQRRVFSWGFGGYGRLGHSEQKDEMLPRLVKMFDFPGRGAASVHAGYSCSFA 302

HSP 4 Score: 80.4925 bits (197), Expect = 2.923e-15
Identity = 45/108 (41.67%), Postives = 66/108 (61.11%), Query Frame = 2

Query: 13256 LVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRP---RIIESLTGKGINRVACGSAHTL 13570
            L+LT  G+VYTWG+GD  +LGHG    V  P  V  L +  ++  ACG  H +C TE G V ++G+N  GQLG G T +N+ P   +I+ S  G+ + +VACG+  ++
Sbjct:   67 LLLTDLGQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAACGRSHTLCITETGVVMAFGENHLGQLGLG-TKSNAMPTPKQIVYS--GQPVVKVACGAEFSM 171

HSP 5 Score: 79.337 bits (194), Expect = 6.916e-15
Identity = 50/155 (32.26%), Postives = 79/155 (50.97%), Query Frame = 2

Query: 1550 HQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLI--GVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H++ CL         +K  V  V +   + H L +T+ GQVY+WG    G+LG GD K  + P  +D   +  L V   ACG  H+L +T++G + + G NH+GQLG G  K   +P   T   ++  G  V ++A     SM +   G ++++G
Sbjct:   44 HRYGCL---------AKVHVSSVVSGPTACHCLLLTDLGQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFK--LTVVAAACGRSHTLCITETGVVMAFGENHLGQLGLG-TKSNAMP---TPKQIVYSGQPVVKVACGAEFSMLVDCKGNLYSFG 183

HSP 6 Score: 76.2554 bits (186), Expect = 6.852e-14
Identity = 46/130 (35.38%), Postives = 70/130 (53.85%), Query Frame = 2

Query: 10142 PQKIECMSLSNVIQIECG--AQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNK-IAHVACGSSHSV 10522
            P +  C++  +V  +  G  A     LT+ GQV+TWG+GD  +LGHG  K +  P  ++ L K  +V  A G  H L +T+ G V ++G+N  GQ G GT + N  PT    +   + +  VACG+  S+
Sbjct:   43 PHRYGCLAKVHVSSVVSGPTACHCLLLTDLGQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAACGRSHTLCITETGVVMAFGENHLGQLGLGTKS-NAMPTPKQIVYSGQPVVKVACGAEFSM 171

HSP 7 Score: 67.3958 bits (163), Expect = 4.309e-11
Identity = 81/333 (24.32%), Postives = 121/333 (36.34%), Query Frame = 2

Query: 12596 GRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQ----PGEDVLT-PTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCIT-KNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNR--KKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTL 13570
            G+VY  G G+ G+LG G  + V+ P  V  L +  VV  A   G  H L +   G+V A+G+    +LGL  +      P + V +   +VK    AE   +               LY++G   YG+LGH    D  F      L         C     + L  T +  D +++ VP                     +C             V  + CGS  +LV  +   V++WG G Y RLGH        P  V   +   +    V  G        E G +Y WG +           +   P+ +  L G  I  +ACG +  +
Sbjct:   73 GQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAAC--GRSHTLCITETGVVMAFGENHLGQLGLGTKSNAMPTPKQIVYSGQPVVKVACGAEFSMLVDCKG---------NLYSFGCPEYGQLGHNT--DGRFLACSNRLE------FVCELAPRRVLVFTERTRDGKVNTVP--------------------AVC-------------VTDIACGSNHTLVRDSQRRVFSWGFGGYGRLGHSEQKDEMLPRLVKMFDFPGRGAASVHAGYSCSFAIIETGALYFWGTSST------MRESTMYPKPVMDLAGWKIRSLACGKSSVM 347

HSP 8 Score: 54.299 bits (129), Expect = 5.495e-7
Identity = 36/86 (41.86%), Postives = 45/86 (52.33%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGH 1873
            V A    SH L +TE G V ++G N  G+LG G TK    PT           VK VACG E S+++   G++YS G    GQLGH
Sbjct:  109 VAAACGRSHTLCITETGVVMAFGENHLGQLGLG-TKSNAMPTPKQIVYSGQPVVK-VACGAEFSMLVDCKGNLYSFGCPEYGQLGH 192

HSP 9 Score: 53.9138 bits (128), Expect = 7.499e-7
Identity = 28/80 (35.00%), Postives = 42/80 (52.50%), Query Frame = 2

Query: 13346 PEKVAQLNRKKIIDVACG--SLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            P +   L +  +  V  G  + HC+  T+ G+VY+WG  D+GQLG G       PR +++L    +   ACG +HTL  T
Sbjct:   43 PHRYGCLAKVHVSSVVSGPTACHCLLLTDLGQVYTWGRGDKGQLGHGDLKRVEAPRPVDALFKLTVVAAACGRSHTLCIT 122

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Yeast
Match: HUL5 (Multiubiquitin chain assembly factor (E4); proteasome processivity factor that elongates polyUb chains on substrates, opposing Ubp6p, a branched polyubiquitin protease; required for retrograde transport of misfolded proteins during ERAD; required for ubiquitination of a subset of cytosolic misfolded proteins upon heat shock [Source:SGD;Acc:S000003109])

HSP 1 Score: 78.1814 bits (191), Expect = 2.860e-14
Identity = 95/319 (29.78%), Postives = 157/319 (49.22%), Query Frame = 2

Query: 14177 DCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKIL----SGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAID--GKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHE--FDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGN-DSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDY-LPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDI 15103
            D GG   E +T + DE           + D+     S   D T  K+  FLG ++G  +  +  + ++ +D   K L    +G   + +DL  +D  L ++L+ L  +   E+++L + + +   +   K V+L I      +V   N   Y+ +V +YK+++  F     F   G+S++I    + +F+S EL+ L+ G  D+I +  LKS T Y G K +D  I+ FWE++ E   E +  FL+FV    + P         +F I    + +  + Y LP A TC  LLKLP+Y +K IL+EKLLYAI+     D+
Sbjct:  597 DGGGITKEFLTTVSDEGFKDPKHELFRTNDRYELYPSVVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSNGFLSSFSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPESSAKVVDL-IPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAF-HGGLSVIIAPHWMEMFNSIELQMLISGERDNIDLDDLKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGI----RNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARFDL 909

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Yeast
Match: TOM1 (E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase [Source:SGD;Acc:S000002865])

HSP 1 Score: 76.6406 bits (187), Expect = 1.368e-13
Identity = 92/336 (27.38%), Postives = 156/336 (46.43%), Query Frame = 2

Query: 14129 LPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP-DKDCFVLSPYADKT------NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKE---VNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCL--FIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLP-RYVSDLRGKEFVIQVLSKYSPADDY-----LPEAYTCFFLLKLPNYSSKAILQEKLLYAIH 15082
            + N   ++   GES  D GG   E    +  ++ N     F+  P DK  F    + ++T      +  +F F+G ++G AIR    L    S  ++K + G+ ++  D++  D D   SL+ +   D T++  ++  +SV   D  E   +NL IE    I V  +N+  Y+ +V+ YK+    K  +  F+  G   +I   L+ +F  +ELE L+ G   I +   K+ T Y    +    + +FW  +     E R+  L+FV G +++P     +L G    +  + K+S   D+     LP ++TCF  L LP Y S   L+  LL AI+
Sbjct: 2936 IKNSKLEITFKGESGVDAGGVTREWYQVLSRQMFNPDYALFLPVPSDKTTF----HPNRTSGINPEHLSFFKFIGMIIGKAIRDQCFLDCHFSREVYKNILGRPVSLKDMESLDPDYYKSLVWILENDITDI--IEETFSVETDDYGEHKVINL-IEGGKDIIVTEANKQDYVKKVVEYKLQTSVKEQMDNFLV-GFYALISKDLITIFDEQELELLISGLPDIDVDDWKNNTTYVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSG----VNGVCKFSIHRDFGSSERLPSSHTCFNQLNLPPYESYETLRGSLLLAIN 3259

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Yeast
Match: SRM1 (Nucleotide exchange factor for Gsp1p; localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p; human homolog of the RAN GEF, RCC1, can complement a temperature sensitive point mutant [Source:SGD;Acc:S000003065])

HSP 1 Score: 70.8626 bits (172), Expect = 2.993e-12
Identity = 89/370 (24.05%), Postives = 140/370 (37.84%), Query Frame = 2

Query: 9488 LPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGD--SSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNS----RLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACG-SRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLG--------------HGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMR-PTLV--SALMDNKIAHVACGSSHSVA 10525
             P L E    +   +    S +LF     G+VY  G    + G LG   D     ++   P ++    KY IV++A   G  H + L + G  F+WG G   +LG       RLK   PR    F  + V  +A G +H  A+     L +WGL  +G+                           CG S D +  AL +                         P+++       +  I  G   S  L+++G +++ G+ D + +G              HG  + +  P ++ ++ K K V  A G+ H +AV   G  YSWG  +    G G    +   PT +  +A  D+ I  V CG   SV+
Sbjct:  158 FPPLAEGHKVVQLAATDNMSCALFS---NGEVYAWGTFRCNEGILGFYQDK---IKIQKTPWKVPTFSKYNIVQLA--PGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRP---FGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQ---------------------------CGVSEDVEDGALVTK------------------------PKRLALPDNVVIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPTKLNNVPKFKSV--AAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEVPTRIKNTATQDHNIILVGCGGQFSVS 463

HSP 2 Score: 69.3218 bits (168), Expect = 9.728e-12
Identity = 59/226 (26.11%), Postives = 103/226 (45.58%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVS-ISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLG--------------HNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG----DTAMRLHPELVK--SLRDYKVVQVACGSR 10039
            ++ WG   ++QLG +   + +L  L+     L  V  I+ G    F +T+  K+   G +  G+ G+  D +  A ++  PKRL   D   I  +A  +G  H++ L+++G+ +S G  D  ++G              H     +  P K+      +   VA GS HS A+   G  Y+WG G+   +G G    DT +   P  +K  + +D+ ++ V CG +
Sbjct:  242 VFAWGNGQQNQLGRKVMERFRLKTLDPRPFGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGA-LVTKPKRLALPDNVVIRSIA--AGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPTKLNNVP--KFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEV---PTRIKNTATQDHNIILVGCGGQ 459

HSP 3 Score: 67.0106 bits (162), Expect = 4.618e-11
Identity = 41/142 (28.87%), Postives = 69/142 (48.59%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQ----VKQVACGEEHSLILTQSGDIYSCGRNHMGQLG--------------HGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +H  A+T+  ++ SWG N  G+ G   ++D +   ++    R  L     ++ +A GE HSLIL+Q GD+YSCGR  M ++G              HG  +   LP ++          K +A   H S+ ++ +G  ++WG
Sbjct:  284 NHCFALTKDNKLVSWGLNQFGQCGV--SEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPTKLNNVPKF----KSVAAGSHHSVAVAQNGIAYSWG 419

HSP 4 Score: 65.4698 bits (158), Expect = 1.396e-10
Identity = 75/302 (24.83%), Postives = 121/302 (40.07%), Query Frame = 2

Query: 9755 ETFSWGEGDDGKLGHNSRLK---LNYPRKIKYFK--GKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHG----------------------------DTAMRLHPELVKSLRD-YKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL----IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIR-EPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQG------NGTVTYNMRPTLVSALMDN-KIAHVACGSSHSV 10522
            + F WG G   +LG     K   +  PR   +      +++  A G  H+ A+    ++++WG  D G LG                               T  ++  E    L + +KVVQ+A  + D  + AL S+  V++WG     +   G     +     P K+   S  N++Q+  G      L E G V+ WG G   +LG    +  R + +         + ++A G  HC A+T   ++ SWG N  GQ G      +G +    +P  + AL DN  I  +A G  HS+
Sbjct:   47 DIFCWGTGSMCELGLGPLAKNKEVKRPRLNPFLPRDEAKIISFAVGGMHTLALDEESNVWSWGCNDVGALGRDTSNAKEQLKDMDADDSSDDEDGDLNELESTPAKIPRESFPPLAEGHKVVQLA--ATDNMSCALFSNGEVYAWGTFRCNEGILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRPFGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALV--TKPKRL-ALPDNVVIRSIAAGEHHSL 343

HSP 5 Score: 64.3142 bits (155), Expect = 2.737e-10
Identity = 62/221 (28.05%), Postives = 99/221 (44.80%), Query Frame = 2

Query: 1373 VEIRPDKLPRE----LNEKFRIKKIVCSGVDTYVLSDCGWLYEVNT-SSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLG-HGDVKDRHL---PIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +E  P K+PRE    L E  ++ ++  +   +  L   G +Y   T   ++ I    F  + I  Q    K    +  +SK  ++ +       H+L + E G V++WG     +LG+    +R R   +D        VK +A GE H   LT+   + S G N  GQ G   DV+D  L   P R+   D   V+++ IA   H S+ LS DG +++ G
Sbjct:  146 LESTPAKIPRESFPPLAEGHKVVQLAATDNMSCALFSNGEVYAWGTFRCNEGI--LGFYQDKIKIQ----KTPWKVPTFSKYNIVQLAPG--KDHILFLDEEGMVFAWGNGQQNQLGR-KVMERFRLKTLDPRPFGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPD--NVVIRSIAAGEHHSLILSQDGDLYSCG 355

HSP 6 Score: 55.0694 bits (131), Expect = 2.369e-7
Identity = 39/138 (28.26%), Postives = 57/138 (41.30%), Query Frame = 2

Query: 13178 ICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVR-KPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLG------DGTTTTNSRPRIIESLTGKGINRVACGSAHTL 13570
            I K P K+ T     ++++  G    L L   G V+ WG G   +LG       R K         + +  +A G  HC   T+D ++ SWG N  GQ G      DG   T  +P+ +       I  +A G  H+L
Sbjct:  208 IQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRPFGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVT--KPKRLALPDNVVIRSIAAGEHHSL 343

HSP 7 Score: 51.6026 bits (122), Expect = 2.441e-6
Identity = 40/136 (29.41%), Postives = 62/136 (45.59%), Query Frame = 2

Query: 13211 EGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFR-----LGHGSDN-HVRK-PEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTT------TTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            EG  V+++      S  L ++GEVY WG    FR     LG   D   ++K P KV   ++  I+ +A G  H +   E+G V++WG+  + QLG          T + RP  +     + +  +A G  H  A T
Sbjct:  163 EGHKVVQLAATDNMSCALFSNGEVYAWGT---FRCNEGILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRPFGL-----RHVKYIASGENHCFALT 290

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Yeast
Match: RSP5 (NEDD4 family E3 ubiquitin ligase; regulates processes including: MVB sorting, the heat shock response, transcription, endocytosis and ribosome stability; ubiquitinates Sec23p, Sna3p, Ste4p, Nfi1p, Rpo21p and Sem1p; autoubiquitinates; deubiquitinated by Ubp2p; regulated by SUMO ligase Siz1p, in turn regulates Siz1p SUMO ligase activity; required for efficient Golgi-to-ER trafficking in COPI mutants; mutant tolerates aneuploidy; human homolog implicated in Liddle syndrome [Source:SGD;Acc:S000000927])

HSP 1 Score: 69.3218 bits (168), Expect = 1.554e-11
Identity = 81/322 (25.16%), Postives = 153/322 (47.52%), Query Frame = 2

Query: 14150 VKLIGESVDDCGGGYSESITEICDELQNGHLPFF----ISSPDKDCFVLSPYA--DKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAID---GKEVNLNIETSGA-IFVNASNRNSYIDEVINYKI-HEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLP-RYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            +K  GE   D GG   E    +  E+ N   PF+     S+ D     ++P +  +  +  +F F+G ++G+ +   + L       ++K++  + +   D++  D ++ +SL     + E  ++ + +  + +A D   G+ V ++++  G  I V   N+  Y++    ++I     +       G + +IP  L+ +F  RELE L+ G   I I   K  T YRG +  D +I WFW+ + E  NE R+  L+F  G +R+P     DL+G +   +   + +     LP+++TCF  + LP Y     +++KL  A+
Sbjct:  486 IKFDGEEGLDYGGVSREFFFLLSHEMFN---PFYCLFEYSAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSL---NWMLENSIDGV-LDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAV 800

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Nematostella
Match: EDO37196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGI6])

HSP 1 Score: 1382.85 bits (3578), Expect = 0.000e+0
Identity = 842/1958 (43.00%), Postives = 1150/1958 (58.73%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRN-------------LQVLVARNLVSNLMARTCSQSTELTKKESDNLPSTANKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLLLVDEIEKFGDSNS--------SKNNGIHHYCD---NKDFVTMMKRTRDISIV--------RESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSV----------MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQ----NGHLPFFISSP--------DKDCFVLSPYA-DKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            K++VWGLNDKDQLG    SK+K+P+L+E +  L    I+GGSK+LF V+  GKV+  G+S+NGRLG+G    ++A V + P+++E L  + + KV+VHSGGRHA+ALT  G+ FSWGEG+DGKLGH +R+  ++P+ I  FK   V D++CGSSHSAAI+  G LYTWGLG+YGRLGHGD    L P+ V+S   ++V+ +ACGSRDAQTLALT D TVWSWGDGDFGKLGRGGS GC +P  +E +    V ++ CGAQ S AL+ +G VWTWGKGDYYRLGHG D H+R+P  ++ L+  KIV +AVGALHCLAVTD GQV++WGDNDHGQQGN T T N RP LV+ L   KI  VACGSSHS+AW  SDL    P+ A +                  P++F  + DPLGA  +             + E TQS +    +  ++ +L   IS  R R +   ++ SL  N             LQ++ AR+ V   +  + +      K    + P+     L+ +    L    L +++    Q+V+  +DL   T      + R +  LL +    + G+           S   G     D         +   T D SIV        +ES HPY ++T  SG V +  A  L VEFDRQCSTER  D L IMD    I++ RSG+ W +W S++ ++G+EL W F SD S+  WGWRF V P+        +  D            LF P+I L++ LL+         S   +L  SL   A     L    R WA+ ++  ++R+ ++G                          P  D P       I       DEE++  S   +  +      +  L + + +Q+++EEP V+  K L +S F K ++ L+C + +D +       EWAWFR +C+  R   SL +   LPY F+ + + + L+       L  E        EY     F  + D Q++ WL  RP  W   W     SG  ++ WGHNHRGQLG +EG+K+K+P   E L+++RP QI+GGEQ+LF V+ +G+VYATG+G+ GRLG+G T++V +  ++  L+  +V KVAV+SGGKH +AL  +G VY+WG+ +D KLG   R         P ++++L    +IDI+ GGSHSA I+++ ELYTWGKGRYGRLGHG+ +DQ  PK+VEALRG  VI VACGSGDAQTLC+T ++           VWSWGDGDYGKLGRGG D CK+PMK+E+L G GV KV+CGSQFS+ LT SG VYTWGKGDY+RLGHG D+HVR+P++VA L  KK+I +A GSLHC+  T+ GEVY+WGDNDEGQLGDGTT   +RPR++ +L GK I+RVACGSAHT+AW+T      +    PD+       P   N L++    +  NR +LLH ++ELFC+++   DL+              +D +R +L+PS+KE+ FR +VQTTM   ++HGP I++NR+                           + R  G    G       K+VFGQ         D +S  G      P+   LP+RVWKVK IGESVDDCGGGYSESI E+CDELQ    NG LP  I +P        ++DCF+L+P A    +   F FLG L+GIAIRT  PLSL +++  WK L+G +L   DL   DKD +  LM ++ +D   LE + +P+S  +  G+E+ L+ +      +   NR  Y+   +N+++HEFD+ C  +R G+  V+P+P L+LF+  ELE +VCG+  IP+  LKS+  Y+G+  +  ++ WFW+ +E  +N  RSLFLRFVWGRTRLPR ++D RG++FV QVL KY+P D YLPE+YTCFFLLK+P YSS  IL EKL YA+HFCKSID DDYARI L 
Sbjct: 2422 KVFVWGLNDKDQLGGLKGSKIKVPVLSEFIGALKVQQIAGGSKTLFAVSHDGKVFACGESTNGRLGLGP---LSANVTV-PRQIENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSCVRDMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGNDTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVNGLEGQKITRVACGSSHSIAWAESDL----PTPATHE-----------------PVMFPVSRDPLGASCL-------------APEPTQSPSATILDTISNNDL---ISGKRHRPSLAKIVLSLNTNCERQQALGHILTALQIIYARDAVVGALMDSQAFLASDPKASPRDDPTDEAVSLASVPEVSLDDVTLTVESHASRQAVV--EDLDEFTAGLGPEDARLLVELLKLAVAGRAGEPGQDVLSRVLRSLAQGRPEIADMLLELCITELEDVTTDNSIVHSAFQPVVQESSHPYTDDTNTSGVVKVAGAEGLRVEFDRQCSTERRHDPLTIMDSTGRILSLRSGREWSEWASELRVSGDELRWKFTSDSSVNGWGWRFTVYPIAPAAAPCDVMSDRA---------LLFRPSIDLVRCLLDFQLETLCSPSQIPRLAASLGACA-QLSTLSASQRTWALHRLRKLLRS-DVG--------------------------PPLDVPTLLGYNLI-------DEEEMAISGSSLGSL------VRGLPEALQRQYEYEEPLVRGGKHLMHSDFFKVMVALACDLGIDLLPCCMDRHEWAWFRRFCMASRIASSLESRLPLPYNFVQDVREKILE-------LIPE--ECGDGEEYVSHTVFKREQDEQLLLWLNQRPSDWTMTW---GGSG-TIYGWGHNHRGQLGSLEGAKVKLPQTIEALASIRPVQIVGGEQTLFAVTAEGKVYATGYGHGGRLGLGGTDTVTSIKMLESLQHVVVRKVAVHSGGKHAMALSADGDVYSWGEGDDGKLGHGNR----NSCDRPRVIEALRGKGVIDISCGGSHSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEALRGNRVIDVACGSGDAQTLCLTDDD----------CVWSWGDGDYGKLGRGGSDGCKIPMKVESLIGLGVSKVECGSQFSVALTRSGAVYTWGKGDYYRLGHGVDDHVRRPKRVAALQGKKVITIATGSLHCVASTDTGEVYTWGDNDEGQLGDGTTNAIARPRLVTALQGKKISRVACGSAHTIAWSTC--KPVNAGRLPDE------VPMEYNHLQHIPLAATRNRLILLHEFSELFCTSVTLFDLDPGHEETLDYGPLVGLDTLRGVLIPSNKETAFRKVVQTTMVRDRQHGPVIELNRIQVK------------------------KYRSKG----GLAGPDGTKSVFGQ-------ACDKMSNFG------PESLFLPHRVWKVKFIGESVDDCGGGYSESIAEMCDELQASYHNGSLPLLIVTPNGREESGANRDCFILNPDATSAVHLGMFRFLGMLIGIAIRTGSPLSLNLAEPTWKQLAGMTLTVTDLAEIDKDYVPGLMCIRDMDAAALEAMDMPFSTPSASGREMRLHAKMK---TICQENREEYVRLALNHRLHEFDQQCSAVREGMGRVVPVPFLSLFTGPELETMVCGSPDIPLDLLKSVVTYKGIDGNAPLVRWFWDTLESFSNAERSLFLRFVWGRTRLPRTIADFRGRDFVFQVLDKYNPPDHYLPESYTCFFLLKMPRYSSHRILCEKLKYAVHFCKSIDSDDYARIDLT 4207

HSP 2 Score: 342.813 bits (878), Expect = 1.280e-93
Identity = 197/381 (51.71%), Postives = 261/381 (68.50%), Query Frame = 2

Query: 12440 LEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGS-TESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            ++V+ WG N + QLGG++GSKIKVPVL E + AL+ +QI GG ++LF VS DG+V+A G   NGRLG+G  + +V  P  +  L   +V KV+V+SGG+H +AL   G +++WG+ ED KLG   R+      L  T   S V+    D++ G SHSAAI  SGELYTWG G YGRLGHG+      PK V++   + VI +ACGS DAQTL +T +           +VWSWGDGD+GKLGRGG + C +P  +E L+G GV KV CG+QFSL L+ SG V+TWGKGDY+RLGHG+D HVRKP+ V  L  KKI+DVA G+LHC+  T+ G+V++WGDND GQ G+ TTT N RP+++  L G+ I RVACGS+H++AW 
Sbjct: 2421 IKVFVWGLNDKDQLGGLKGSKIKVPVLSEFIGALKVQQIAGGSKTLFAVSHDGKVFACGESTNGRLGLGPLSANVTVPRQIENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSCVR----DMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDD----------GTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQGQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGNDTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVNGLEGQKITRVACGSSHSIAWA 2787

HSP 3 Score: 283.878 bits (725), Expect = 7.801e-76
Identity = 150/293 (51.19%), Postives = 192/293 (65.53%), Query Frame = 2

Query: 9662 PKRLEALD-KYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            P  LE L  K  IV+V  H+ G+H +ALT+ GE +SWG GD GKLGH        P  +    GK+V+ ++CGS+HSAA+   G LYTWG G+YGRLGHG +  +L P LV  LR + ++ VACGS DA TLA   D TVWSWGDGD+GKLGRGGS GC  P+ IE +    V ++ CGAQ S ALT +G VWTWGKG+ +RLGHGT+ H+R P  +E L    +V ++VG++HCLA+TD G+VY WG ND GQ G+        PTLVS L    I  +ACG + S AW+ +
Sbjct:    5 PAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWSCA 297

HSP 4 Score: 256.144 bits (653), Expect = 2.252e-67
Identity = 155/307 (50.49%), Postives = 198/307 (64.50%), Query Frame = 2

Query: 12662 QTPILVSGLEEKI-VVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWT 13579
            Q P  +  L  K  +V+V  ++ GKH LAL   G VY+WG  +  KLG      P E+   PTLV  L   ++I I+ G +HSAA++  GELYTWG+G YGRLGHG+ +DQ  P +V  LRG+H+I VACGSGDA TL    +           +VWSWGDGDYGKLGRGG D CK P  IE L+G GV KV CG+QFSL LT  G V+TWGKG+ FRLGHG+++HVR P+ V  L+ K ++DV+ GS+HC+  T+ GEVY WG ND+GQLGD        P ++  L  KGI  +ACG A + AW+
Sbjct:    3 QPPAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHG-DTSPREE---PTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADD----------GTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWS 295

HSP 5 Score: 144.05 bits (362), Expect = 1.420e-33
Identity = 100/304 (32.89%), Postives = 157/304 (51.64%), Query Frame = 2

Query: 9512 SELDCVS---------ISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGS--SHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIR-EPMQIEDLKKTKIVHLAVGALHCLAVTDRGQ 10387
            +EL+C+S              K    +TR G+VY  G    G+LG G DT    E    P  +  L    +++++   G  H+ A+T  GE ++WG G+ G+LGH S      P  +   +G  ++DVACGS  +H+ A    G +++WG GDYG+LG G +    +P+ ++ L+   V +V CG++   +LALT D +VW+WG G+  +LG G       P+ +E +   +V+ +  G+    ALT+ G+V+ WG+ D  +LG   D  IR EP  +  L    IV +A G     A +  GQ
Sbjct:    6 AELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHG-DTSPREE----PTLVTGLAGKQVIRISC--GSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGAQ--FSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGD-IDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWSCAGQ 299

HSP 6 Score: 124.405 bits (311), Expect = 1.171e-27
Identity = 98/280 (35.00%), Postives = 147/280 (52.50%), Query Frame = 2

Query: 12569 QSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXE--LYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVR-KPEKVAQLNRKKIIDVACG 13399
            +    ++ +G VY+ G G+ G+LG G T   + P LV+GL  K V++++   G  H  A+ + G +Y WG     +LG        ED L P LV  L    IID+A G   +  ++ + +  +++WG G YG+LG G  D    PK +E L+G  V  V CG+    +L +T+          + SVW+WG G+  +LG G  D  + P  +E L+G  V+ V  GS   L LT +GEVY WG+ D  +LG   D  +R +P  V+ L  K I+ +ACG
Sbjct:   27 KHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISC--GSTHSAAVTSEGELYTWGRGNYGRLGHG----SSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSIERLQGLGVCKVYCGA--QFSLALTR----------DGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGD-IDCQIRPEPTLVSGLASKGIVGIACG 287

HSP 7 Score: 122.094 bits (305), Expect = 6.911e-27
Identity = 77/265 (29.06%), Postives = 128/265 (48.30%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSK--IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRT--GKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLA 10057
            +Y+W      KL     S  E+PT  +    +  +     S   + + S+  +Y WG  +  +LG  ++    +P+L   L     + ++ GS     +     G V+  GD   G+LG G      ++    PK +E L    + K  V+ G + ++ALT++G  ++WG+G+  +LGH +   + +P+ ++   GK VVDV+ GS H  A+   G +Y WG  D G+LG  D  +R  P LV  L    +V +ACG   AQ+ A
Sbjct:   38 VYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGG-----SDGCKNPKSIERLQGLGVCK--VYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGP--AQSFA 293

HSP 8 Score: 121.324 bits (303), Expect = 1.042e-26
Identity = 97/280 (34.64%), Postives = 138/280 (49.29%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGED-VLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGE 13279
            EV+SWG    G+LG  + S  + P L   L+  +  +I  G      V+ +G +Y  G GN GRLG GS+E    P+LVSGL    ++ VA  SG  H LA  ++G V++WGD +  KLG     + G D    P  ++ L    +  +  G   S A++R G ++TWGKG   RLGHG  D    PK+VEAL G HV+ V+ GS      C+         L     V+ WG  D G+LG     I   P  +  L   G++ + CG   S   + +G+
Sbjct:   37 EVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLG-----RGGSDGCKNPKSIERLQGLGVCKVYCGAQFSLALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKHVVDVSVGS----IHCLA--------LTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIVGIACGPAQSFAWSCAGQ 299

HSP 9 Score: 113.235 bits (282), Expect = 3.171e-24
Identity = 77/271 (28.41%), Postives = 129/271 (47.60%), Query Frame = 2

Query: 9266 NNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMS--KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGS--KSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTS 10066
            +  +Y+W +    KL     ++ + P        +  ++        + I    ++Y WG     +LG   +    LP + EAL     + ++ GS      C+T    V+  GD   G+LG G            P ++E+L    + K  V  G + ++ALT++G  ++WG+GD  +LGH     +  P+++   +GK+V+ +A GS H  A    G +YTWG  D G+LG G T     P LV +L+  K+ +VACGS  A T+A ++
Sbjct: 3459 DGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALRGKGVIDISCGGSHSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEALRGNRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKI-----PMKVESLIGLGVSK--VECGSQFSVALTRSGAVYTWGKGDYYRLGHGVDDHVRRPKRVAALQGKKVITIATGSLHCVASTDTGEVYTWGDNDEGQLGDGTTNAIARPRLVTALQGKKISRVACGS--AHTIAWST 3720

HSP 10 Score: 99.7525 bits (247), Expect = 4.106e-20
Identity = 51/143 (35.66%), Postives = 84/143 (58.74%), Query Frame = 2

Query: 1589 LWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV---DGHQSMCLSNDGAIFTWG 2008
            L  K  ++ V  +    H LA+T  G+VYSWG+   GKLG GDT  R+ PT++   +    QV +++CG  HS  +T  G++Y+ GR + G+LGHG  +D+ +P+ +  S L G  +  +A    D H ++  ++DG +++WG
Sbjct:   11 LSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLA--GKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLV--SGLRGHHIIDVACGSGDAH-TLAAADDGTVWSWG 148

HSP 11 Score: 93.9745 bits (232), Expect = 1.837e-18
Identity = 46/136 (33.82%), Postives = 76/136 (55.88%), Query Frame = 2

Query: 10142 PQKIECMSLS-NVIQI--ECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD 10540
            P ++EC+S    ++Q+      +   ALT  G+V++WG GD  +LGHG      EP  +  L   +++ ++ G+ H  AVT  G++Y+WG  ++G+ G+G+    + P LVS L  + I  VACGS  +    A+D
Sbjct:    5 PAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHHIIDVACGSGDAHTLAAAD 140

HSP 12 Score: 92.8189 bits (229), Expect = 4.069e-18
Identity = 60/187 (32.09%), Postives = 98/187 (52.41%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWGS---------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSV-LLKSGSVYTWLK 2164
            H +A++  G VYSWG    GKLG G+     RP +I+        V  ++CG  HS  +TQ+ ++Y+ G+   G+LGHGD +D+ LP  + A  L G  V  +A      Q++CL++D  +++WG            D C+  +     K+E+ +    ++++      S +SV L +SG+VYTW K
Sbjct: 3452 HAMALSADGDVYSWGEGDDGKLGHGNRNSCDRPRVIEALR--GKGVIDISCGGSHSACITQNHELYTWGKGRYGRLGHGDSEDQLLPKVVEA--LRGNRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPM-----KVESLIGLGVSKVEC----GSQFSVALTRSGAVYTWGK 3625

HSP 13 Score: 84.7297 bits (208), Expect = 1.238e-15
Identity = 42/124 (33.87%), Postives = 69/124 (55.65%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTF-SRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            H +A+T  G+++SWG    GKLG G+  +   P +IDTF S C   V+ ++CG  HS  +  SG++Y+ G    G+LGHGD      P ++ +     V+         Q++ L++DG +++WG
Sbjct: 2520 HAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSC---VRDMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVWSWG 2640

HSP 14 Score: 76.2554 bits (186), Expect = 4.488e-13
Identity = 47/136 (34.56%), Postives = 70/136 (51.47%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            NRVIDV      +  L +T+   V+SWG    GKLG+G +   K P  +++     L V +V CG + S+ LT+SG +Y+ G+    +LGHG       P R+ A  L G  V  IA      +  ++ G ++TWG
Sbjct: 3545 NRVIDVACGSGDAQTLCLTDDDCVWSWGDGDYGKLGRGGSDGCKIPMKVESL--IGLGVSKVECGSQFSVALTRSGAVYTWGKGDYYRLGHGVDDHVRRPKRVAA--LQGKKVITIATGSLHCVASTDTGEVYTWG 3676

HSP 15 Score: 75.485 bits (184), Expect = 7.053e-13
Identity = 43/139 (30.94%), Postives = 73/139 (52.52%), Query Frame = 2

Query: 1592 WSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++ +RVID+      +  LA+T+ G V+SWG    GKLG+G ++    P  ++        V +VACG + SL L+ SG +++ G+    +LGHG+  D H+        L G  +  +AV     + +++ G +F WG
Sbjct: 2610 FTSHRVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPVEKLQ--GQGVCKVACGAQFSLALSTSGLVWTWGKGDYYRLGHGN--DTHVRKPQIVDGLRGKKIVDVAVGALHCLAVTDSGQVFAWG 2744

HSP 16 Score: 72.4034 bits (176), Expect = 6.483e-12
Identity = 43/132 (32.58%), Postives = 69/132 (52.27%), Query Frame = 2

Query: 1619 DANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACG--EEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            D +  SSH  A+  +G++Y+WG    G+LG GD     +P  + +F+  H +V  +ACG  +  +L LT  G ++S G    G+LG G  +   +P  +    L G  V ++A     S+ LS  G ++TWG
Sbjct: 2565 DMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTS-H-RVIDIACGSRDAQTLALTDDGTVWSWGDGDFGKLGRGGSEGCSVPNPV--EKLQGQGVCKVACGAQFSLALSTSGLVWTWG 2692

HSP 17 Score: 72.0182 bits (175), Expect = 1.002e-11
Identity = 41/127 (32.28%), Postives = 65/127 (51.18%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            S+H  AVT  G++Y+WG    G+LG G ++D+  P ++      H  +  VAC  G+ H+L     G ++S G    G+LG G       P  I    L G+ V ++      S+ L+ DG+++TWG
Sbjct:   78 STHSAAVTSEGELYTWGRGNYGRLGHGSSEDQLVPVLVSGLRGHH--IIDVACGSGDAHTLAAADDGTVWSWGDGDYGKLGRGGSDGCKNPKSI--ERLQGLGVCKVYCGAQFSLALTRDGSVWTWG 200

HSP 18 Score: 66.6254 bits (161), Expect = 3.485e-10
Identity = 47/134 (35.07%), Postives = 68/134 (50.75%), Query Frame = 2

Query: 5567 LLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG--PNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKK 5962
            L+L++GVLGL QT++R     + G      ++      ++ + +  K   T       L    +A    LK GT V+RG DWK+GDQDG  P+   I+     +G  RVQW     T SYR GK+  YDL+L +
Sbjct: 1273 LVLSSGVLGLTQTIMRLAGPCDTGE-----EEDAALAAIIDEGKAAKKRPTV-----PLTGPEVA--KMLKIGTRVVRGPDWKWGDQDGPPPSEGRIIGELGEDGWARVQW-ETGSTNSYRMGKEGKYDLKLAR 1393

HSP 19 Score: 62.7734 bits (151), Expect = 5.162e-9
Identity = 32/84 (38.10%), Postives = 50/84 (59.52%), Query Frame = 2

Query: 13340 RKPEKVAQLNRK-KIIDVACGS--LHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTT 13582
            + P ++  L+RK +I+ V   +   H +  T +GEVYSWG  D G+LG G T+    P ++  L GK + R++CGS H+ A T+
Sbjct:    3 QPPAELECLSRKCEIVQVVTHTDGKHFLALTREGEVYSWGSGDGGKLGHGDTSPREEPTLVTGLAGKQVIRISCGSTHSAAVTS 86

HSP 20 Score: 61.6178 bits (148), Expect = 1.172e-8
Identity = 41/168 (24.40%), Postives = 84/168 (50.00%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVK-DRHLPIRITASDLIGVLVKQIAVD--GHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNE-IDQIQVHDSTYSVLLKSGSVYTW 2158
            +V+ WG N   +LG       K P + +      L+V+Q+A G +    ++  G +++CG +  G+LG G +  +  +P +I   +L   +V++++V   G  +M L+ +G +F+WG   D    H +  +      ++ +++  +  +    S  + +L SG +YTW
Sbjct: 2422 KVFVWGLNDKDQLGGLKGSKIKVPVLSEFIGA--LKVQQIAGGSKTLFAVSHDGKVFACGESTNGRLGLGPLSANVTVPRQI--ENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDTFKSSCVRDMSCGSSHSAAILSSGELYTW 2585

HSP 21 Score: 60.077 bits (144), Expect = 3.255e-8
Identity = 38/115 (33.04%), Postives = 55/115 (47.83%), Query Frame = 2

Query: 1646 LAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG 1990
            LA+T  G V++WG     +LG G     + P +++     H  V  V+ G  H L LT +G++Y  GRN  GQLG  D + R  P  ++     G++   IA    QS   S  G
Sbjct:  188 LALTRDGSVWTWGKGEGFRLGHGTEDHVRHPKLVEALDGKH--VVDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLASKGIV--GIACGPAQSFAWSCAG 298

HSP 22 Score: 56.6102 bits (135), Expect = 3.814e-7
Identity = 45/179 (25.14%), Postives = 79/179 (44.13%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGD-TKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWS---PKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            S  + AV+  G+V++ G +T+G+LG G  + +   P  I+  S   ++   V  G  H++ LT  G ++S G    G+LGHG+  +   P  I         V+ ++     S  + + G ++TWG        H  N++   PK       +R         D+    L   G+V++W
Sbjct: 2463 SKTLFAVSHDGKVFACGESTNGRLGLGPLSANVTVPRQIENLSSFMVRKVSVHSGGRHAMALTIEGKLFSWGEGEDGKLGHGNRMNCDHPKLIDT--FKSSCVRDMSCGSSHSAAILSSGELYTWGLGEYGRLGHGDNYTHLKPKKVQSFTSHRVIDIACGSRDAQTLALTDDGTVWSW 2639

HSP 23 Score: 55.8398 bits (133), Expect = 7.640e-7
Identity = 25/70 (35.71%), Postives = 41/70 (58.57%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQS 1825
            VD  + + H LAVT++GQV++WG N  G+ G   T   +RP +++       ++ +VACG  HS+   +S
Sbjct: 2722 VDVAVGALHCLAVTDSGQVFAWGDNDHGQQGNNTTTVNRRPQLVNGLE--GQKITRVACGSSHSIAWAES 2789

HSP 24 Score: 55.0694 bits (131), Expect = 1.316e-6
Identity = 42/124 (33.87%), Postives = 66/124 (53.23%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            + AVT  G+VY+ G    G+LG G T       ++++    H+ V++VA   G +H++ L+  GD+YS G    G+LGHG+      P  I A  L G  V  I+  G  S C++ +  ++TWG
Sbjct: 3399 LFAVTAEGKVYATGYGHGGRLGLGGTDTVTSIKMLESLQ--HVVVRKVAVHSGGKHAMALSADGDVYSWGEGDDGKLGHGNRNSCDRPRVIEA--LRGKGVIDISCGGSHSACITQNHELYTWG 3518

HSP 25 Score: 53.1434 bits (126), Expect = 4.940e-6
Identity = 26/71 (36.62%), Postives = 40/71 (56.34%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSG 1828
            VD ++ S H LA+T+AG+VY WG N  G+LG  D + R  PT++   +     +  +ACG   S   + +G
Sbjct:  230 VDVSVGSIHCLALTDAGEVYCWGRNDQGQLGDIDCQIRPEPTLVSGLAS--KGIVGIACGPAQSFAWSCAG 298

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Nematostella
Match: EDO45583 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSK9])

HSP 1 Score: 435.261 bits (1118), Expect = 3.041e-126
Identity = 329/1082 (30.41%), Postives = 535/1082 (49.45%), Query Frame = 2

Query: 12005 LQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSI-------SPV--------STADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETES--PDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDL----------NRQS---VMDKVRQILLPS-SKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKL--IEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYA-DKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIP---YSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDY 15112
            L  ++L Q+ +E+ ++    QL +S FL+SL  L+  + LD +       +P+        +   EW W +++C+     ++L             F+ RF K   V  P   +I+         D   +S   D Q++ W   RP+ W      ++    + + WG    GQL    G  + VP + + L++   +Q++ G+   F+V ++G + A G G+ GRLG+G+++ + T   +S L+  +V+++A + G   H LAL ++G V++WGD +  KLG        +    P  +++L   E++++A G  HSA ++  G+L+T+G G YGRLGHGN  ++  P+ V AL  + +  VACG      L    N           +VW++GDGDYGKLG G       P  I+ L G G  K+ CG+QFS+VLT  G V+++G+        G     +KP+++  L    I DV  G+ H +  T  GEV+ WG+N +GQLG G +     P +I  L GK I +++ G  H+ AWT           +  P Q       P     L   S V++  R  +LHH+++L  S+     L          NR +   V  ++R +L    S   + R M +T + G K +GP+I V RL                                    +GR K    K +F Q+  ++  ++ AD                 LP+R WKVKL+GE  DD GG + ++ITE+C EL+ G +   I +P        ++D F+L+P A  + +   + FLG L G+A+RT +PL L ++ L+WK L G  L  +D++  +       +    +DET    + IP   +   + DG+ V + + +   I +  SNR+ Y+++ + +++ EFD+    +R G+  ++P+PLL+L +   LE LVCG+  + +  LK +  YR +   D ++ W W ++E  TNE R LF+RFV GR+RLP  V D+  +  ++    K     D LP A TCFF L+LP YSS+  +  +L YAI+ C+SID+D+Y
Sbjct:  349 LPTIMLDQYNYEKAKLSRGDQLVHSPFLQSLAALTVGLDLDRVMCHALSRAPIPPCSWNEANALPEWLWLKSFCVAVHAADALT------------FRERFQKNFLV--PNEEKISEDEPFQPL-DNSSWSLTMDEQVMAWAMRRPEDW------ETGGKCDAYLWGGGRHGQLA-ESGRGVNVPTVTKSLAS--AQQVVCGQNCTFVVQVNGTILACGEGSYGRLGMGNSDDLFTLSPISALQGYVVIQIATSRGSDGHSLALTDSGEVFSWGDGDYGKLGHG----NSDRQRRPRQIEALRGEEVVNMACGFKHSAVVTVDGKLFTFGNGDYGRLGHGNSANKKTPERVTALEKHAIGQVACGLNHTLVLSADGN-----------TVWAFGDGDYGKLGLGSCTAKTSPQAIDVLAGIGCKKICCGTQFSVVLTNDGRVFSFGQERLTGQPEGRLRGPQKPQQIQALASHFIDDVCVGAEHVLALTSTGEVWGWGNNVDGQLGLGHSNAQREPCVIPDLKGKNIRQISAGRNHSAAWTAPPPPPRFPPGAPMPLQLGHPEHTPPQFPALAEVSTVAVRARLRVLHHFSDLVYSSWKMFSLMPGEVEAHAYNRGTIGFVRGQLRPLLATRVSNLPIVRAMGRTMVQG-KNYGPQITVKRL------------------------------------IGRGK--KSKAIFVQIATQVTKLKSAD---------------LCLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELEEGVVNLLIHTPNSTAEVGFNRDRFLLNPAATSEDDLVLYKFLGILFGVAVRTKKPLDLHLAPLVWKQLVGIPLTPDDIE--ESLRGIRDIHESGVDETTFAEI-IPIETFETQSADGRFVPM-VPSGHNIHLTFSNRSEYVEQALKFRLQEFDRQVAAVREGMGWILPVPLLSLLTPDNLEQLVCGSAEVSVDMLKRVVRYREIDPSDSLVSWLWRVLESFTNEERILFMRFVSGRSRLPANVGDITQRFQLV----KLDRGVDSLPTAQTCFFQLRLPPYSSQEAMANRLRYAINNCRSIDMDNY 1329

HSP 2 Score: 221.861 bits (564), Expect = 1.531e-57
Identity = 141/371 (38.01%), Postives = 210/371 (56.60%), Query Frame = 2

Query: 9428 YVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDF-TVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            Y+WG     QL  E+   V +P + ++L+    V    G    F V   G +   G+ S GRLG+G+  D+     + P  + AL  Y ++++A   G   H++ALT +GE FSWG+GD GKLGH +  +   PR+I+  +G+ VV++ACG  HSA +   G L+T+G GDYGRLGHG++A +  PE V +L  + + QVACG     TL L++D  TVW++GDGD+GKLG G  +    PQ I+ ++     +I CG Q S  LT +G+V+++G+        G  +  ++P QI+ L    I  + VGA H LA+T  G+V+ WG+N  GQ G G       P ++  L    I  ++ G +HS AWTA
Sbjct:  491 YLWGGGRHGQLA-ESGRGVNVPTVTKSLASAQQVVC--GQNCTFVVQVNGTILACGEGSYGRLGMGNSDDL---FTLSP--ISALQGYVVIQIATSRGSDGHSLALTDSGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALRGEEVVNMACGFKHSAVVTVDGKLFTFGNGDYGRLGHGNSANKKTPERVTALEKHAIGQVACGLN--HTLVLSADGNTVWAFGDGDYGKLGLGSCTAKTSPQAIDVLAGIGCKKICCGTQFSVVLTNDGRVFSFGQERLTGQPEGRLRGPQKPQQIQALASHFIDDVCVGAEHVLALTSTGEVWGWGNNVDGQLGLGHSNAQREPCVIPDLKGKNIRQISAGRNHSAAWTA 851

HSP 3 Score: 88.5817 bits (218), Expect = 7.693e-17
Identity = 79/267 (29.59%), Postives = 127/267 (47.57%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGET-FSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALT 10219
            +++ WG  D  +LG   + + + P   EAL   + V+++ G K    VT  GK++  G+   GRLG G+  +        P+R+ AL+K+ I +VA   G  H + L+ +G T +++G+GD GKLG  S      P+ I    G     + CG+  S  +   G ++++G         G       P+ +++L  + +  V  G+     LALTS   VW WG+   G+LG G S+    P  I  +   N+ QI  G   S A T
Sbjct:  593 EVFSWGDGDYGKLGHGNSDRQRRPRQIEALRGEEVVNMACGFKHSAVVTVDGKLFTFGNGDYGRLGHGNSANKKT-----PERVTALEKHAIGQVAC--GLNHTLVLSADGNTVWAFGDGDYGKLGLGSCTAKTSPQAIDVLAGIGCKKICCGTQFSVVLTNDGRVFSFGQERLTGQPEGRLRGPQKPQQIQALASHFIDDVCVGAE--HVLALTSTGEVWGWGNNVDGQLGLGHSNAQREPCVIPDLKGKNIRQISAGRNHSAAWT 850

HSP 4 Score: 80.4925 bits (197), Expect = 1.738e-14
Identity = 42/118 (35.59%), Postives = 70/118 (59.32%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG 1990
             H LA+T++G+V+SWG    GKLG G++  ++RP  I+       +V  +ACG +HS ++T  G +++ G    G+LGHG+  ++  P R+TA  L    + Q+A   + ++ LS DG
Sbjct:  583 GHSLALTDSGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALR--GEEVVNMACGFKHSAVVTVDGKLFTFGNGDYGRLGHGNSANKKTPERVTA--LEKHAIGQVACGLNHTLVLSADG 696

HSP 5 Score: 67.0106 bits (162), Expect = 2.652e-10
Identity = 50/178 (28.09%), Postives = 86/178 (48.31%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGD-IYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS---TFDNCRRHLSNWSP-KIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            H   VT  G+++++G    G+LG G++ ++K P  +    + H  + QVACG  H+L+L+  G+ +++ G    G+LG G    +  P  I    L G+  K+I      S+ L+NDG +F++G    T     R      P +I+   + +   ID + V       L  +G V+ W
Sbjct:  636 HSAVVTVDGKLFTFGNGDYGRLGHGNSANKKTPERVTALEK-H-AIGQVACGLNHTLVLSADGNTVWAFGDGDYGKLGLGSCTAKTSPQAIDV--LAGIGCKKICCGTQFSVVLTNDGRVFSFGQERLTGQPEGRLRGPQKPQQIQALASHF---IDDVCVGAEHVLALTSTGEVWGW 806

HSP 6 Score: 58.151 bits (139), Expect = 1.112e-7
Identity = 37/117 (31.62%), Postives = 58/117 (49.57%), Query Frame = 2

Query: 1670 VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAV----DGHQSMCLSNDGAIFTWG 2008
             Y WG    G+L +       R   + T ++     +QV CG+  + ++  +G I +CG    G+LG G+  D      I+A  L G +V QIA     DGH S+ L++ G +F+WG
Sbjct:  490 AYLWGGGRHGQLAESG-----RGVNVPTVTKSLASAQQVVCGQNCTFVVQVNGTILACGEGSYGRLGMGNSDDLFTLSPISA--LQGYVVIQIATSRGSDGH-SLALTDSGEVFSWG 598

HSP 7 Score: 57.7658 bits (138), Expect = 1.480e-7
Identity = 37/145 (25.52%), Postives = 69/145 (47.59%), Query Frame = 2

Query: 1640 HVLAVTEAGQ-VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCV 2071
            H L ++  G  V+++G    GKLG G    +  P  ID  +   +  K++ CG + S++LT  G ++S G+  +     G ++    P +I A  L    +  + V     + L++ G ++ WG+  D  +  L + + + E CV
Sbjct:  688 HTLVLSADGNTVWAFGDGDYGKLGLGSCTAKTSPQAIDVLA--GIGCKKICCGTQFSVVLTNDGRVFSFGQERLTGQPEGRLRGPQKPQQIQA--LASHFIDDVCVGAEHVLALTSTGEVWGWGNNVDG-QLGLGHSNAQREPCV 827

HSP 8 Score: 53.5286 bits (127), Expect = 2.856e-6
Identity = 36/116 (31.03%), Postives = 58/116 (50.00%), Query Frame = 2

Query: 1664 GQVYSWGTNTSGKLGQGDTKDRKRPTIIDTF-SRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            G + + G  + G+LG G++ D    + I        +Q+      + HSL LT SG+++S G    G+LGHG+   +  P +I A  L G  V  +A     S  ++ DG +FT+G
Sbjct:  537 GTILACGEGSYGRLGMGNSDDLFTLSPISALQGYVVIQIATSRGSDGHSLALTDSGEVFSWGDGDYGKLGHGNSDRQRRPRQIEA--LRGEEVVNMACGFKHSAVVTVDGKLFTFG 650

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Nematostella
Match: EDO32366 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVB1])

HSP 1 Score: 198.364 bits (503), Expect = 4.059e-57
Identity = 95/201 (47.26%), Postives = 138/201 (68.66%), Query Frame = 2

Query: 14480 KAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIH 15082
            + +D   LE + +P+S  +  G+E+ L+ +      +   NR  Y+   +N+++HEFD+ C  +R G+  V+P+P L+LF+  ELE +VCG+  IP+  LKS+  Y+G+  +  ++ WFW+ +E  +N  RSLFLRFVWGRTRLPR ++D RG++FV QVL KY+P D YLPE+YTCFFLLK+P YSS  IL EKL YA+H
Sbjct:   22 RDMDAAALEAMDMPFSTPSASGREMRLHAKMKT---ICQENREEYVRLALNHRLHEFDQQCSAVREGMGRVVPVPFLSLFTGPELETMVCGSPDIPLDLLKSVVTYKGIDGNAPLVRWFWDTLESFSNAERSLFLRFVWGRTRLPRTIADFRGRDFVFQVLDKYNPPDHYLPESYTCFFLLKMPRYSSHRILCEKLKYAVH 219

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Nematostella
Match: EDO45579 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSK3])

HSP 1 Score: 204.142 bits (518), Expect = 2.774e-52
Identity = 146/380 (38.42%), Postives = 205/380 (53.95%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVD-VACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDF-TVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGT-DKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNM-RPTLVSALMDNKIAHVACGSSHSVAWTASDLD 10546
            ++YVWG N   QL   +  K+ +P L  +        I  G    F +   G V+  G  S GRLG+G  T+ T       KRL   ++  +  V+   G   H +ALT +G+ +SWG+GD GKLGH +      P+ ++   G +VV  +A G  HSAA+   G LYTWG GDYGRLGHGD   R  P  VK + +  V QVACGS  A T+ ++ D  TVWS+G GD GKLG   ++    P+ IE +    + ++ CG+Q S ALT  GQV+ WG G    LG G+ D     P  +  L+   +V ++VG  HC+A+T    VY+WG+N  GQ G G  T  + +P  V  L    +  ++ G+SH+VAWTA  +D
Sbjct:  365 EVYVWGSNSSHQLAEGSMDKILVPKLATSFGSAQ--QIEAGQYCTFVIFPDGFVHACGKGSYGRLGLGDSTNQTQL-----KRLNFDNECLVKSVSSSKGSDGHTLALTLDGKVYSWGDGDYGKLGHGNSQTQKIPKLVEGALGNKVVCCIAAGYRHSAAVTEDGELYTWGEGDYGRLGHGDNNSRNVPVQVKDVAN--VGQVACGS--AHTVCVSQDGQTVWSFGSGDNGKLGHSDTNRVYKPKVIEALQGMVIRKVCCGSQCSLALTSTGQVYVWGCGP--SLGTGSVDATSATPKLLLALQSHSVVDISVGDSHCVALTQDNNVYAWGNNSMGQCGQGHCTTPITKPKKVLGLDGVAVHQISAGTSHTVAWTALPMD 731

HSP 2 Score: 184.882 bits (468), Expect = 2.287e-46
Identity = 149/393 (37.91%), Postives = 214/393 (54.45%), Query Frame = 2

Query: 12431 ASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVK-SLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGS-DNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTN-SRPRIIESLTGKGINRVACGSAHTLAWTTVSGNK 13597
            AS  EV+ WG N   QL      KI VP L     +   +QI  G+   F++  DG V+A G G+ GRLG+G ST   Q   L    E  +    +      H LAL  +G VY+WGD +  KLG        +    P LV+ +L    +  IAAG  HSAA++  GELYTWG+G YGRLGHG+ + +  P  V+ +   +V  VACGS  A T+C++++           +VWS+G GD GKLG    +    P  IE L+G  + KV CGSQ SL LT++G+VY WG G    LG GS D     P+ +  L    ++D++ G  HC+  T+D  VY+WG+N  GQ G G  TT  ++P+ +  L G  +++++ G++HT+AWT +  ++
Sbjct:  361 ASNEEVYVWGSNSSHQLAEGSMDKILVPKLATSFGS--AQQIEAGQYCTFVIFPDGFVHACGKGSYGRLGLGDSTNQTQLKRLNFDNECLVKSVSSSKGSDGHTLALTLDGKVYSWGDGDYGKLGHG----NSQTQKIPKLVEGALGNKVVCCIAAGYRHSAAVTEDGELYTWGEGDYGRLGHGDNNSRNVPVQVKDVA--NVGQVACGS--AHTVCVSQD---------GQTVWSFGSGDNGKLGHSDTNRVYKPKVIEALQGMVIRKVCCGSQCSLALTSTGQVYVWGCGP--SLGTGSVDATSATPKLLLALQSHSVVDISVGDSHCVALTQDNNVYAWGNNSMGQCGQGHCTTPITKPKKVLGLDGVAVHQISAGTSHTVAWTALPMDR 732

HSP 3 Score: 106.301 bits (264), Expect = 2.945e-22
Identity = 95/290 (32.76%), Postives = 141/290 (48.62%), Query Frame = 2

Query: 12734 HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSR-----IDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIK-VDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGE-VYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTT 13582
            H  +  +N  VY WG    ++L         + +L P L  S   A+ I+     +          ++  GKG YGRLG G+  +Q   K +                D + L  + +         + L  +  V+SWGDGDYGKLG G     K+P  +E   G  V+  +  G + S  +T  GE+YTWG+GDY RLGHG +N    P +V  +    +  VACGS H +C ++DG+ V+S+G  D G+LG   T    +P++IE+L G  I +V CGS  +LA T+
Sbjct:  356 HGNSFASNEEVYVWGSNSSHQLAEGSM----DKILVPKLATSFGSAQQIEAGQYCTFVIFPDGF--VHACGKGSYGRLGLGDSTNQTQLKRLNF--------------DNECLVKSVSSSKGSDGHTLALTLDGKVYSWGDGDYGKLGHGNSQTQKIPKLVEGALGNKVVCCIAAGYRHSAAVTEDGELYTWGEGDYGRLGHGDNNSRNVPVQVKDV--ANVGQVACGSAHTVCVSQDGQTVWSFGSGDNGKLGHSDTNRVYKPKVIEALQGMVIRKVCCGSQCSLALTS 623

HSP 4 Score: 82.8037 bits (203), Expect = 3.384e-15
Identity = 64/216 (29.63%), Postives = 108/216 (50.00%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDG-AIFTWGSTFDNCRRHLSN----WSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW---LKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGD 2263
            H LA+T  G+VYSWG    GKLG G+++ +K P +++  +  +  V  +A G  HS  +T+ G++Y+ G    G+LGHGD   R++P+++     +G    Q+A     ++C+S DG  ++++GS  DN +   S+    + PK+   +      I ++         L  +G VY W       T    +    P+L  +L  Q  +V  IS GD
Sbjct:  461 HTLALTLDGKVYSWGDGDYGKLGHGNSQTQKIPKLVEG-ALGNKVVCCIAAGYRHSAAVTEDGELYTWGEGDYGRLGHGDNNSRNVPVQVKDVANVG----QVACGSAHTVCVSQDGQTVWSFGSG-DNGKLGHSDTNRVYKPKVIEALQGMV--IRKVCCGSQCSLALTSTGQVYVWGCGPSLGTGSVDATSATPKL--LLALQSHSVVDISVGD 666

HSP 5 Score: 53.5286 bits (127), Expect = 3.033e-6
Identity = 37/132 (28.03%), Postives = 67/132 (50.76%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRC-HLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            ++A  Y + V  +   G V++ G  + G+LG GD+ ++ +   ++  + C    V      + H+L LT  G +YS G    G+LGHG+ + + +P ++    L   +V  IA     S  ++ DG ++TWG
Sbjct:  400 IEAGQYCTFV--IFPDGFVHACGKGSYGRLGLGDSTNQTQLKRLNFDNECLVKSVSSSKGSDGHTLALTLDGKVYSWGDGDYGKLGHGNSQTQKIP-KLVEGALGNKVVCCIAAGYRHSAAVTEDGELYTWG 528

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Nematostella
Match: EDO49099 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI68])

HSP 1 Score: 137.117 bits (344), Expect = 1.201e-32
Identity = 106/329 (32.22%), Postives = 164/329 (49.85%), Query Frame = 2

Query: 9581 VYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFG---GHLYTWGLGDYGRLG-HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIEC---MSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLG----HGTDKHIREPMQIEDLKKT--KIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNK-IAHVACGSSHSVA 10525
            +Y  G+ +NG LG G DT         P  +EAL    I KVA   G  H +AL+K+GE FSWG G  G+LG         P +I   +   +  VAC   HSAA+      G L+++G  DYG+LG   D  +  + + V SL ++K+ +VACGS    + AL    ++W WG  + G+LG G  +   +P  +E    +    V+++ CG Q S  +T+ G+++  G   Y +LG       D H+   + +     T  + VH+A G  H   VTD G++++WG    G+ G+G       PT +   M+ K +  V+CG +H+  
Sbjct:  209 IYTWGEGTNGMLGHGEDTQEAH-----PHVVEALLGKDIRKVAC--GATHTLALSKDGEVFSWGSGYGGRLGQGHLRDRFTPIRICGLESLNLTQVACNEFHSAAVCACSKQGALFSFGENDYGQLGIPEDKLLTSYIQCVSSLSEHKISRVACGS--FHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPTDFRCVHVACGDSHTAVVTDGGEIFTWGRGKGGRLGHGDNLNRHLPTEIEIGMEGKHVRGVSCGRAHTAC 528

HSP 2 Score: 128.257 bits (321), Expect = 1.006e-29
Identity = 87/273 (31.87%), Postives = 139/273 (50.92%), Query Frame = 2

Query: 9755 ETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGS-RDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIEC---MSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIE---DLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQG-------NGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWT 10531
            + ++WGEG +G LGH    +  +P  ++   GK +  VACG++H+ A+   G +++WG G  GRLG G    R  P  +  L    + QVAC     A   A +    ++S+G+ D+G+LG       L+   I+C   +S   + ++ CG+  S AL E+G +W WG  +  +LG+G       P  +E   DL+   ++ +A G  H   +T +G+++  GDN +GQ G       +  VTYN+    V    D +  HVACG SH+   T
Sbjct:  208 DIYTWGEGTNGMLGHGEDTQEAHPHVVEALLGKDIRKVACGATHTLALSKDGEVFSWGSGYGGRLGQGHLRDRFTPIRICGLESLNLTQVACNEFHSAAVCACSKQGALFSFGENDYGQLGIPEDK--LLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNV-AVRVRVPTDFRCVHVACGDSHTAVVT 477

HSP 3 Score: 112.079 bits (279), Expect = 1.348e-24
Identity = 101/385 (26.23%), Postives = 174/385 (45.19%), Query Frame = 2

Query: 9299 LNKLRFQMNSNTEDPTT---NSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAI-ALTKNGETFSWGEGDDGKLG-HNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKS---LRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXX------------XXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIE-DLKKTKIVHLAVGALHCLAVTDRGQV 10390
            +NK+ F+ + +  D  T       L + TV  ++++         IY WG      LG    ++   P + EAL   D   ++ G+     +++ G+V+  G    GRLG G   D        P R+  L+   + +VA +     A+ A +K G  FS+GE D G+LG    +L  +Y + +      ++  VACGS HSAA+   G L+ WG  + G+LG+G+      P L+++   LR   V++VACG  D  +  +T    ++  GD  +G+            +    +    +P    C      + + CG   +  +T+ G+++TWG+G   RLGHG + +   P +IE  ++   +  ++ G  H      R  V
Sbjct:  171 MNKVDFEDSQDQTDSGTVEVEFGLLGQATVHVKEDA-------CDIYTWGEGTNGMLGHGEDTQEAHPHVVEALLGKDIRKVACGATHTLALSKDGEVFSWGSGYGGRLGQGHLRD-----RFTPIRICGLESLNLTQVACNEFHSAAVCACSKQGALFSFGENDYGQLGIPEDKLLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACG--DQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPTDFRC------VHVACGDSHTAVVTDGGEIFTWGRGKGGRLGHGDNLNRHLPTEIEIGMEGKHVRGVSCGRAHTACTVTRAWV 535

HSP 4 Score: 108.612 bits (270), Expect = 2.017e-23
Identity = 100/334 (29.94%), Postives = 159/334 (47.60%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALC---NNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTL--VKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEA---LRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVA-QLNRKKIIDVACGSLHCIC 13417
            ++++WG    G LG  E ++   P + E L     R++  G      +S DG V++ G G  GRLG G      TPI + GLE   + +VA N    H  A+C     G ++++G+ +  +LG+     P + +LT  +  V SL + +I  +A G  HSAA++  G L+ WG    G+LG+GN      P ++EA   LR   V+ VAC  GD  +  ITK    R+    + +    G                + +++ T      + V CG   + V+T  GE++TWG+G   RLGHG + +   P ++   +  K +  V+CG  H  C
Sbjct:  208 DIYTWGEGTNGMLGHGEDTQEAHPHVVEALLGKDIRKVACGATHTLALSKDGEVFSWGSGYGGRLGQGHLRDRFTPIRICGLESLNLTQVACNE--FHSAAVCACSKQGALFSFGENDYGQLGI-----PEDKLLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVAC--GDQHSAFITKK--GRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPT--DFRCVHVACGDSHTAVVTDGGEIFTWGRGKGGRLGHGDNLNRHLPTEIEIGMEGKHVRGVSCGRAHTAC 528

HSP 5 Score: 105.531 bits (262), Expect = 1.608e-22
Identity = 80/228 (35.09%), Postives = 120/228 (52.63%), Query Frame = 2

Query: 12929 ELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTA---SGEVYTWGKGDYFRLGHGSDNHVRKP-EKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIES---LTGKGINRVACGSAHTLAWTTVSG 13591
            ++YTWG+G  G LGHG    +  P +VEAL G  +  VACG+    TL ++K+ +          V+SWG G  G+LG+G       P++I  LE   + +V C    S  + A    G ++++G+ DY +LG   D  +    + V+ L+  KI  VACGS H     E G ++ WG N+ GQLG+G  T+ S P ++E+   L    +  VACG  H+ A+ T  G
Sbjct:  208 DIYTWGEGTNGMLGHGEDTQEAHPHVVEALLGKDIRKVACGA--THTLALSKDGE----------VFSWGSGYGGRLGQGHLRDRFTPIRICGLESLNLTQVACNEFHSAAVCACSKQGALFSFGENDYGQLGIPEDKLLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHS-AFITKKG 422

HSP 6 Score: 102.834 bits (255), Expect = 1.043e-21
Identity = 106/344 (30.81%), Postives = 157/344 (45.64%), Query Frame = 2

Query: 12602 VYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-DIRVQPGEDVLTPTLV---KSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQ---PFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIET---LEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLG-HGSDN---HVRK--PEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIE-SLTGKGINRVACGSAHTLAWTT 13582
            +Y  G G NG LG G       P +V  L  K + KVA   G  H LAL  +G V++WG     +LG   +R     D  TP  +   +SL   ++       +   A S+ G L+++G+  YG+LG    +D+    + + V +L  + +  VACGS  +  L              + S+W WG  + G+LG G +    LP  +E    L    V++V CG Q S  +T  G ++  G   Y +LG H +DN   HV      +V      + + VACG  H    T+ GE+++WG    G+LG G       P  IE  + GK +  V+CG AHT    T
Sbjct:  209 IYTWGEGTNGMLGHGEDTQEAHPHVVEALLGKDIRKVAC--GATHTLALSKDGEVFSWGSGYGGRLGQGHLR-----DRFTPIRICGLESLNLTQVACNEFHSAAVCACSKQGALFSFGENDYGQLG--IPEDKLLTSYIQCVSSLSEHKISRVACGSFHSAAL------------AEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPTDFRCVHVACGDSHTAVVTDGGEIFTWGRGKGGRLGHGDNLNRHLPTEIEIGMEGKHVRGVSCGRAHTACTVT 531

HSP 7 Score: 78.1814 bits (191), Expect = 5.500e-14
Identity = 65/248 (26.21%), Postives = 118/248 (47.58%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTE-AGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCL---SNDGAIFTWGSTFDNCRRHLSNWSPKIET----CVNEY-RNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDI------QPELDTVLK----YQVDNVSMISKGDGEFYFLDKSG 2293
             ++V+  +     + V E A  +Y+WG  T+G LG G+      P +++        +++VACG  H+L L++ G+++S G  + G+LG G ++DR  PIRI    L  + + Q+A +   S  +   S  GA+F++G   +N    L     K+ T    CV+    ++I ++       + L + GS++ W      CN+S  +         L ++L+     + D V  ++ GD    F+ K G
Sbjct:  187 TVEVEFGLLGQATVHVKEDACDIYTWGEGTNGMLGHGEDTQEAHPHVVEAL--LGKDIRKVACGATHTLALSKDGEVFSWGSGYGGRLGQGHLRDRFTPIRICG--LESLNLTQVACNEFHSAAVCACSKQGALFSFG---ENDYGQLGIPEDKLLTSYIQCVSSLSEHKISRVACGSFHSAALAEHGSLWLW-----GCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKG 422

HSP 8 Score: 74.7146 bits (182), Expect = 7.715e-13
Identity = 48/148 (32.43%), Postives = 76/148 (51.35%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRC-HLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGH--GDVKDRHLPIRITASDLIGVLVKQIAV---DGHQSMCLSNDGAIFTWG-------STFDNCRRHL 2038
            S H  A+ E G ++ WG N SG+LG G+      P++++  +   H  V +VACG++HS  +T+ G ++ CG N  GQLG    D +D H+   +     +    + + V   D H ++ +++ G IFTWG          DN  RHL
Sbjct:  357 SFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQHSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPTDFRCVHVACGDSHTAV-VTDGGEIFTWGRGKGGRLGHGDNLNRHL 503

HSP 9 Score: 63.5438 bits (153), Expect = 1.783e-9
Identity = 45/170 (26.47%), Postives = 82/170 (48.24%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCG--WLYEVNTSSDDVIDTFTFKH-NAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQ--GDTKDRKRPTIIDTFSRCHLQVK--QVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRI 1909
            +I ++ C    +  L++ G  WL+  N S       +T     ++    + L++D+V+++   ++           H   +T+ G+++  G NT G+LG    D +D      +    R     +   VACG+ H+ ++T  G+I++ GR   G+LGHGD  +RHLP  I
Sbjct:  349 KISRVACGSFHSAALAEHGSLWLWGCNESGQLGNGNYTSTSLPSLLEAGNDLRHDAVMEVACGDQ-----------HSAFITKKGRMFCCGDNTYGQLGAHLNDNQDDHVTYNVAVRVRVPTDFRCVHVACGDSHTAVVTDGGEIFTWGRGKGGRLGHGDNLNRHLPTEI 507

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Medaka
Match: herc2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:NCBI gene;Acc:101167612])

HSP 1 Score: 940.258 bits (2429), Expect = 0.000e+0
Identity = 591/1321 (44.74%), Postives = 803/1321 (60.79%), Query Frame = 2

Query: 11231 IVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQF-EDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQ--------SV-MDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSP--------DKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDET--ELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALN 15130
            +V ES HPY ++T  SG V IP A  L +EFDRQ STER  D L IMD  N IV+ RS + W DW S++ I G+EL W F SDGS+  WGWRF V P+      + +          ++   L  P++ L+  LL+   L F  + S+  +L  SL+  A ++       R+WA++++  ++         ++ ++I+   +L     +++ ++           F   A                      +   +  L + + +Q+++E+P V+  KQL +S F K L+ L+C + LD++   +   +WAWFR YC   R   +L   +SL   F++E   +  +       L  +   ++ + E  D   F  +HD Q+V W+ +RPD W     + +     ++ WGHNHRGQLGG+EG+K+KVP   E L+ LRP Q+IGGEQ+LF V+ DG++YATG+G  GRLGIG TESV TP L+  ++   + KVAVNSGGKHCLAL + G VY+WG+AED KLG   R  P +    P +++SL   E++DIAAGG+HSA I+ SGEL+TWGKGRYGRLGHG+ +DQ  PK+V+AL+G+ VI VACGSGDAQTLC+T ++           VWSWGDGDYGKLGRGG D CK+PMKI++L G GV+KV+CGSQFS+ LT SG VYT GKGDY RLGHGSD+HVR+P +V  L  KK+I +A GSLHC+CCTED EVY+WGDNDEGQLGDGTT    RPR++ +L GK INRVACGSAHTLAW+T     ++  + P Q       P   N L+  S ++L NR LLLHH++ELFC  +   DL  +        SV  D +R IL+   KE+ FR +VQ TM   ++HGP +++NR+        G                            G       K+VFGQ+  K+           S F   PD  LLP+RVWKVK + ESVDDCGGGYSESI E+C+ELQN   P  I +P        ++DCF+L+P A    +   F FL  LLGIAIRT  PLSL +++ +WK L+G SL   DL   DKD +  LM ++  + T  E E + +P++V    G+++ L+ + S    +   NR  Y+   INY +HEFD+    +R G++ V+P+PLL+LF+  ELE +VCG+  IP+  LKS+  Y+GV+    +I WFWE+ME  +N  RSLFLRFVWGRTRLPR ++D RG++FV+QVL KY+P D +LPE+YTCFFLLKLP YS K +L+EKL YAIHFCKSID DDYARIAL 
Sbjct: 3556 VVVESSHPYTDDTSTSGTVKIP-AEGLRIEFDRQSSTERRHDPLTIMDGANRIVSVRS-REWSDWSSELRIPGDELKWKFTSDGSVNGWGWRFTVYPIMPAAPKDLL----------SDRCILSCPSMDLVTCLLD-FRLNFASNRSIVPRLAASLA--ACAQLSALAGHRMWALQRLRKLLTT-------EYGQSININRLLGDGDGEARSIS-----------FTGSA----------------------LAALVKGLPEALQRQYEYEDPIVRGGKQLLHSPFFKVLVALACDLELDTLPCCAETHKWAWFRRYCTASRVAVALDKRTSLARAFLDEVTKKIRE-------LMADHENMSGLHESHD--LFKREHDEQLVQWM-NRPDDWT----LSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR--PCD---RPRVIESLRGVEVVDIAAGGAHSACITASGELFTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDD----------MVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYT-GKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTED-EVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWST--SKPTNAGKMPAQ------VPMEYNHLQEISVMALRNRLLLLHHFSELFCPCIPMFDLEGRLGQTGHGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSKG----------------------------GLAGPDGTKSVFGQMCAKM-----------SSF--SPDSLLLPHRVWKVKFV-ESVDDCGGGYSESIAEMCEELQNSLTPLLIVTPNGRDESGANRDCFLLNPAAKSPLHMGMFRFL-VLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMTLPFTVPNASGQDIQLSSKYS---HITLENRAEYVRLAINY-LHEFDEQVSAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGVEPTAPLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVVQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALT 4735

HSP 2 Score: 450.284 bits (1157), Expect = 1.325e-125
Identity = 260/494 (52.63%), Postives = 328/494 (66.40%), Query Frame = 2

Query: 9407 SRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLM 10888
            + I +K++VWGLNDKDQLG    SK+K+P  +E LS L+ V ++GGSKSLF  T  GK+Y  G+++NGRLG+G    +++  I  P+++ AL  Y + KVAVHS  RHA+ALT +G+ FSWGEGDDGKLGH SR   + PR I+  K KR+ D+ACGSSHSAAI   G LY+WGLG+YGRLGHGD   +L P+LVK L  ++V+QVACGSRDAQTLALT +  V+SWGDGDFGKLGRGGS GC IPQ IE ++   V QIECGAQ S ALT++G VWT GKGDY+RLGHGTD H+R+P  +E L+  KIVH+AVGALHCLAVTD GQVY+WGDNDHGQQGNGT T N +PTLV  L   KI  VACGSSHSVAWT  D+ +          P + E           P+LF+   D LGA  +   D +     N+       K        N  +L+ ++  L G   +   +  +   LQ++ A  +V  LM
Sbjct: 2904 ASIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLF-ATVEGKIYACGEATNGRLGLG----LSSGTIQIPRQISALSNYVVKKVAVHS--RHAMALTVDGKVFSWGEGDDGKLGHFSR-NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDEL-VFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWT-GKGDYFRLGHGTDVHVRKPQIVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVTT----------PSVHE-----------PVLFQTARDSLGASYLVQSDSDSSAASNKMSGQNSLK-------PNRPSLAKILLSLDGNLAKQQALSHVLSALQIMYADAVVGALM 3359

HSP 3 Score: 355.91 bits (912), Expect = 3.618e-97
Identity = 193/394 (48.98%), Postives = 265/394 (67.26%), Query Frame = 2

Query: 9425 IYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSF--LPSQALNRWPHIKEMS 10600
            IY WG N + QLG    +KVK+P   EAL+ L  V + GG ++LF VT  GK+Y     + G    G       E +  P  LE++   FI KVAV+SGG+H +AL+  GE +SWGE +DGKLGH +R   + PR I+  +G  VVD+A G +HSA I   G L+TWG G YGRLGHGD+  +L P+LV +L+ ++V+ VACGS DAQTL LT D  VWSWGDGD+GKLGRGGS GC +P KI+ ++   V+++ECG+Q S ALT++G V+T GKGDY+RLGHG+D H+R P Q++ L+  K++ +A G+LHC+  T+  +VY+WGDND GQ G+GT     RP LV+AL   KI  VACGS+H++AW+ S   +   +P+Q    + H++E+S
Sbjct: 3893 IYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLY-----ATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNR-PCDRPRVIESLRGVEVVDIAAGGAHSACITASGELFTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYT-GKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTE-DEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKINRVACGSAHTLAWSTSKPTNAGKMPAQVPMEYNHLQEIS 4278

HSP 4 Score: 338.191 bits (866), Expect = 8.651e-92
Identity = 207/398 (52.01%), Postives = 275/398 (69.10%), Query Frame = 2

Query: 12401 AWKKCWPIDSASGL--EVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTV 13585
            A KK   ++SA+ +  +V+ WG N + QLGG++GSKIKVP   E LSAL   Q+ GG +SLF  +++G++YA G   NGRLG+G S+ ++Q P  +S L   +V KVAV+S  +H +AL  +G V++WG+ +D KLG   R     +   P L+++L    I DIA G SHSAAI+ SGELY+WG G YGRLGHG+   Q  PK+V+ L G+ VI VACGS DAQTL +T           +  V+SWGDGD+GKLGRGG + C +P  IE L G GV +++CG+QFSL LT SG V+T GKGDYFRLGHG+D HVRKP+ V  L  KKI+ VA G+LHC+  T+ G+VY+WGDND GQ G+GTTT N +P +++ L G+ I RVACGS+H++AWTTV
Sbjct: 2893 ARKKSSGLESAASIRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLF-ATVEGKIYACGEATNGRLGLGLSSGTIQIPRQISALSNYVVKKVAVHS--RHAMALTVDGKVFSWGEGDDGKLGHFSR-----NCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALT-----------DELVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWT-GKGDYFRLGHGTDVHVRKPQIVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTV 3270

HSP 5 Score: 264.233 bits (674), Expect = 1.982e-69
Identity = 162/377 (42.97%), Postives = 222/377 (58.89%), Query Frame = 2

Query: 9416 MSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKR----VVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTA 10534
            + ++  WGL     LG +  + V  PI  +ALS      I    K    ++R+G VY     S                 + P  +  L    IVK+A H  G+H +AL+ +GE +SWG GD G+LGH     L  P  I  F GK+    VV +ACGS++SAA+   G LYTWG G+YGRLGH    +   P LV +L+  KVV VACGS DAQTLA+T +  VWSWGDGD+GKLGRGGS GC  P+ +E +   +++++ CG+Q S ALT++GQV+TWGKGD  RLGHGTD+H+R P  ++ L+K K+V +AVG+ HCLA+TD G+V+SWG ND  Q  +       +P  +  L    I  ++CG   S AW++
Sbjct:  395 LQEVIAWGL-----LGWKLYANVCGPIHCKALSSTGVTQIVCSEKVFLILSRSGAVYTQNYKST---------------TLAPMLIHGLSSRKIVKLAAHPDGQHFLALSTSGEVYSWGCGDGGRLGHGDAY-LEEPALITTFSGKQTGKQVVQIACGSTYSAAVTADGELYTWGRGNYGRLGHSSEDVTT-PMLVTALKGQKVVDVACGSGDAQTLAVTEN-QVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSLQK-KVVDIAVGSTHCLALTDEGEVHSWGSNDKLQHFDTLFPNKKQPKALPGLNSKHIVGISCGPGQSFAWSS 747

HSP 6 Score: 244.973 bits (624), Expect = 1.587e-63
Identity = 165/395 (41.77%), Postives = 233/395 (58.99%), Query Frame = 2

Query: 12413 CWPIDSASG--LEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGL-DIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVS 13588
            C P +  SG   EV +WG      LG    + +  P+ C+ LS+    QI+  E+   I+S  G VY   + +          +   P+L+ GL  + +VK+A +  G+H LAL  +G VY+WG  +  +LG  D  ++  E  L  T        +++ IA G ++SAA++  GELYTWG+G YGRLGH + +D   P +V AL+G  V+ VACGSGDAQTL +T+N+           VWSWGDGDYGKLGRGG D CK P  +E L+   ++KV CGSQFS+ LT  G+VYTWGKGD  RLGHG+D HVR P+ +  L +KK++D+A GS HC+  T++GEV+SWG ND+ Q  D       +P+ +  L  K I  ++CG   + AW++ S
Sbjct:  385 CSPPNCNSGSLQEVIAWG-----LLGWKLYANVCGPIHCKALSSTGVTQIVCSEKVFLILSRSGAVYTQNYKS----------TTLAPMLIHGLSSRKIVKLAAHPDGQHFLALSTSGEVYSWGCGDGGRLGHGDAYLE--EPALITTFSGKQTGKQVVQIACGSTYSAAVTADGELYTWGRGNYGRLGHSS-EDVTTPMLVTALKGQKVVDVACGSGDAQTLAVTENQ-----------VWSWGDGDYGKLGRGGSDGCKTPKLVEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLLDSL-QKKVVDIAVGSTHCLALTDEGEVHSWGSNDKLQHFDTLFPNKKQPKALPGLNSKHIVGISCGPGQSFAWSSCS 749

HSP 7 Score: 117.087 bits (292), Expect = 5.489e-25
Identity = 85/265 (32.08%), Postives = 127/265 (47.92%), Query Frame = 2

Query: 9749 NGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGA--LHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            +G  + WG    G+LG     K+  P   +     R V +  G     A+   G LY  G G  GRLG G T     P L++S++   + +VA  S     LAL+S+  V+SW           G+  C  P+ IE +    V+ I  G   S  +T +G+++TWGKG Y RLGHG  +   +P  ++ L+  +++ +A G+     L +TD   V+SWGD D+G+ G G       P  + +L    +  V CGS  SVA T S
Sbjct: 3890 SGTIYGWGHNHRGQLGGIEGAKVKVPTPTEALATLRPVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSW-GEAEDGKLGHGNRPCDRPRVIESLRGVEVVDIAAGGAHSACITASGELFTWGKGRYGRLGHGDSEDQLKPKLVDALQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKS 4153

HSP 8 Score: 94.3597 bits (233), Expect = 3.808e-18
Identity = 126/497 (25.35%), Postives = 213/497 (42.86%), Query Frame = 2

Query: 4589 MRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAYKAAL--MLKKPKKS--TDYWQ----------IVYNFVMKKFAGKI------RQNK-SAAIKLVDNSENIR-------------EFCGQIYQFLLNKESIDLQKLRTLVLAK----KIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQ-ILRENLLVNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDG-PNSVGIVKREC-INGMVRVQWLNNKKTASYRAGKDNFYDLRL 5956
            + Q  ++ +   +  V +  +  +  +IK HQ+   SYKE+C+ +  R RFL +E+     N+ +I +  K            L ++ P  RW+ I  K       K+PKKS  TD  +            +        GK       +QNK    +  V N +  R                  I +F L +E +D++K+R  +L +    +++ + +  +LK     L     LLP VQ ++L          +    G   E +YD LK  + +  FN + L      L   YS  + +I+ IL E      + ++ +    + N       +G    A+  L++ + L  ++   ++   LLL +G+L L Q++LR    ++    ++          V+ +SR     T        + +S   L + +K GT V+RG DWK+GDQDG P  +G V  E   +G +RVQW +   T SYR GK+  YDL+L
Sbjct: 1426 VEQGKQRSLPKSVIDVCRMVYQAKCSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVSNDLSIVSKLK------------LLSSQP--RWRRITQKLIRDQRKKRPKKSESTDVEEPKLENEETNEEEHQISPTPAEGKPLPVKPPKQNKWQPVLNTVANVQRYRWLKHSVPSAFSQSSLMASIVEFALKEEPLDVEKMRKCLLKQLERAEVRLEGIDTMLK-----LASKSFLLPSVQYAML------CGWQRVIPEGTNIEPLYDCLKDVDLIPPFNRMLLEVTFGKL---YSWAIQNIRNILLEASARFKELVQLVPLQTITNENPAGPSLGTIPQARFLLAMIHML--SLKHGSNSLSLLLNSGILALTQSILRLIPSTDSSEEDLSACSHGGSATVLEESRKEAAPTP-------VPASGPELAAMMKIGTRVVRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQW-DTSSTNSYRMGKEGKYDLKL 1884

HSP 9 Score: 90.1225 bits (222), Expect = 7.557e-17
Identity = 66/198 (33.33%), Postives = 106/198 (53.54%), Query Frame = 2

Query: 1595 SKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFS--RCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLS-NDGAIFTWG-STFDNCRRHLSNW--SPKIETCVNEYRNEIDQIQV-HDSTYSVLL-KSGSVYTWLK 2164
            S  +++ + A+    H LA++ +G+VYSWG    G+LG GD    + P +I TFS  +   QV Q+ACG  +S  +T  G++Y+ GR + G+LGH   +D   P+ +TA  L G  V  +A     +  L+  +  +++WG   +    R  S+   +PK+     E   ++D ++V   S +SV L K G VYTW K
Sbjct:  464 SSRKIVKLAAHPDGQHFLALSTSGEVYSWGCGDGGRLGHGDAY-LEEPALITTFSGKQTGKQVVQIACGSTYSAAVTADGELYTWGRGNYGRLGHSS-EDVTTPMLVTA--LKGQKVVDVACGSGDAQTLAVTENQVWSWGDGDYGKLGRGGSDGCKTPKL----VEKLQDLDIVKVCCGSQFSVALTKDGQVYTWGK 653

HSP 10 Score: 85.8853 bits (211), Expect = 1.426e-15
Identity = 62/193 (32.12%), Postives = 100/193 (51.81%), Query Frame = 2

Query: 1616 VDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDG--HQSMCLSNDGAIFTWG---------STFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVH-DSTYSVLL-KSGSVYT 2155
            V  N    H LA++  G+VYSWG    GKLG G+ +   RP +I++     ++V  +A G  HS  +T SG++++ G+   G+LGHGD +D+  P  + A  L G  V  +A      Q++CL++D  +++WG            D C+  +     KI++        +  ++V   S +SV L KSG+VYT
Sbjct: 3981 VAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGN-RPCDRPRVIESLR--GVEVVDIAAGGAHSACITASGELFTWGKGRYGRLGHGDSEDQLKPKLVDA--LQGHRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPM-----KIDSLTG-----LGVVKVECGSQFSVALTKSGAVYT 4158

HSP 11 Score: 79.337 bits (194), Expect = 1.600e-13
Identity = 51/181 (28.18%), Postives = 88/181 (48.62%), Query Frame = 2

Query: 1472 CGWLYEVNTSSDDVIDTFT-FKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            CG  Y    ++D  + T+    +  + H  + +    ++      +V+DV      +  LAVTE  QV+SWG    GKLG+G +   K P +++      L + +V CG + S+ LT+ G +Y+ G+    +LGHG  +    P  +   D +   V  IAV     + L+++G + +WGS
Sbjct:  530 CGSTYSAAVTADGELYTWGRGNYGRLGHSSEDVTTPMLVTALKGQKVVDVACGSGDAQTLAVTE-NQVWSWGDGDYGKLGRGGSDGCKTPKLVEKLQ--DLDIVKVCCGSQFSVALTKDGQVYTWGKGDNQRLGHGTDEHVRYPKLL---DSLQKKVVDIAVGSTHCLALTDEGEVHSWGS 704

HSP 12 Score: 77.411 bits (189), Expect = 5.431e-13
Identity = 43/128 (33.59%), Postives = 71/128 (55.47%), Query Frame = 2

Query: 1628 IYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLS-NDGAIFTWG 2008
            ++S H +A+T  G+V+SWG    GKLG   +++  +P +I+       +++ +ACG  HS  +T SG++YS G    G+LGHGD   +  P  +    L+G  V Q+A     +  L+  D  +F+WG
Sbjct: 3000 VHSRHAMALTVDGKVFSWGEGDDGKLGH-FSRNCDKPRLIEALKT--KRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKV--LLGHRVIQVACGSRDAQTLALTDELVFSWG 3122

HSP 13 Score: 72.4034 bits (176), Expect = 1.679e-11
Identity = 66/230 (28.70%), Postives = 100/230 (43.48%), Query Frame = 2

Query: 1667 QVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHG-DVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTW----LKYCTECNKSDDIQPEL-DTVLKYQVDNVS---------------MISKGDGEFYFLDKSG 2293
            +V+ WG N   +LG       K P+  +T S   L V QVA G + SL  T  G IY+CG    G+LG G       +P +I+A  L   +VK++AV    +M L+ DG +F+WG   D    H S    K           I  I    S  + +  SG +Y+W           + +  ++P+L   +L ++V  V+               + S GDG+F  L + G
Sbjct: 2909 KVFVWGLNDKDQLGGLKGSKIKVPSFSETLS--ALNVVQVAGGSK-SLFATVEGKIYACGEATNGRLGLGLSSGTIQIPRQISA--LSNYVVKKVAVHSRHAMALTVDGKVFSWGEGDDGKLGHFSRNCDKPRLIEALKTKRIRDIACGSSHSAAITSSGELYSWGLGEYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDELVFSWGDGDFGKLGRGG 3133

HSP 14 Score: 71.2478 bits (173), Expect = 3.845e-11
Identity = 48/136 (35.29%), Postives = 70/136 (51.47%), Query Frame = 2

Query: 1601 NRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +RVIDV      +  L +T+   V+SWG    GKLG+G +   K P  ID+ +   L V +V CG + S+ LT+SG +Y+ G+    +LGHG   D H+        L G  V  IA      +C + D  ++TWG
Sbjct: 4081 HRVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDSLT--GLGVVKVECGSQFSVALTKSGAVYT-GKGDYHRLGHG--SDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTED-EVYTWG 4210

HSP 15 Score: 70.8626 bits (172), Expect = 4.984e-11
Identity = 41/134 (30.60%), Postives = 75/134 (55.97%), Query Frame = 2

Query: 1607 VIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFT 2002
            V+D+ A    +H   +T +G++++WG    G+LG GD++D+ +P ++D   + H +V  VAC  G+  +L LT    ++S G    G+LG G      +P++I +  L G+ V ++      S+ L+  GA++T
Sbjct: 4031 VVDIAAG--GAHSACITASGELFTWGKGRYGRLGHGDSEDQLKPKLVDAL-QGH-RVIDVACGSGDAQTLCLTDDDMVWSWGDGDYGKLGRGGSDGCKVPMKIDS--LTGLGVVKVECGSQFSVALTKSGAVYT 4158

HSP 16 Score: 67.781 bits (164), Expect = 4.735e-10
Identity = 74/245 (30.20%), Postives = 108/245 (44.08%), Query Frame = 2

Query: 1643 VLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVAC--GEEHSLILTQSGDIYSCGRNHMGQLGHGDVK-DRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSN---WSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIK 2359
            + AVT  G++Y+ G    G+LG G T+    PT++++    H+ +K+VA   G +H L L+  G++YS G    G+LGHG+   DR    R+  S L GV V  IA  G  S C++  G +FTWG        H  +     PK+          +D +Q H     V   SG   T       C   DD+                + S GDG++  L + G    K  MKI     +G G +K
Sbjct: 3936 LFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQ--HVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGNRPCDRP---RVIES-LRGVEVVDIAAGGAHSACITASGELFTWGKGRYGRLGHGDSEDQLKPKL----------VDALQGH-RVIDVACGSGDAQTL------CLTDDDM----------------VWSWGDGDYGKLGRGGSDGCKVPMKI--DSLTGLGVVK 4139

HSP 17 Score: 64.6994 bits (156), Expect = 3.967e-9
Identity = 51/197 (25.89%), Postives = 90/197 (45.69%), Query Frame = 2

Query: 1421 RIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLK-NDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            RI+ I C    +  ++  G LY               ++  + H  +  +    ++K+   +RVI V      +  LA+T+   V+SWG    GKLG+G ++    P  I+  +     V Q+ CG + SL LT+SG +++ G+    +LGHG   D H+        L G  +  +AV     + +++ G ++ WG
Sbjct: 3045 RIRDIACGSSHSAAITSSGELYSWGLG----------EYGRLGHGDNTTQLRPKLVKVLLGHRVIQVACGSRDAQTLALTDE-LVFSWGDGDFGKLGRGGSEGCNIPQNIERLN--GQGVCQIECGAQFSLALTKSGVVWT-GKGDYFRLGHG--TDVHVRKPQIVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3225

HSP 18 Score: 57.7658 bits (138), Expect = 5.350e-7
Identity = 32/118 (27.12%), Postives = 61/118 (51.69%), Query Frame = 2

Query: 1469 DCGWLYEVNTSSDDVIDTFTFKHNAINHQFDC-LKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILT 1819
            +CG  + +  +   V+ T    +  + H  D  ++   +++     +++ V   + + H LAVT++GQVY+WG N  G+ G G T   ++PT++        ++ +VACG  HS+  T
Sbjct: 3155 ECGAQFSLALTKSGVVWTGKGDYFRLGHGTDVHVRKPQIVEGLRGKKIVHV--AVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLE--GQKITRVACGSSHSVAWT 3268

HSP 19 Score: 54.299 bits (129), Expect = 5.082e-6
Identity = 94/423 (22.22%), Postives = 155/423 (36.64%), Query Frame = 2

Query: 7346 ASRACSIKSSISVQELKKALSQLATNIYSGSEEKEPMGSNAKLTDFDYIENSMGIQR----KEKKRKSSALSKIMKSKNPHKESRRDPLNINMDLQFQIMEMGFSKRQIQAAVKELARNGNLYLTSNPESIITTILSFQQDDYSLSPXXXXXXXXXXXXXXXXXSTGLNLTDDNSSCSTVCDHLQYMMPMHQLHSPTVSDNDDKIYDLYGNDDILTNDDEAFNAXXXXXXXXXXXXKPMTSDVEKNFNLKGEFNVVCVNNFGEIFVGDQG-ILSCDGDAI-DGYCNVFWTKISKTISTEKLNIHIFTNPTMS----IIIGDEVTFSESGIRFHSVPAMTSLSN--GIVRQ----IVRLDSEDDDLKIIVDFPNCIGKVCNISDLKLVVKGQHKYQCQACLKSPISLPMYKCKICRNLYLCSNC 8566
            A++   IK+    QE++ A   LA   Y   E   P     + +        + +Q     K+KK+K+S +                PL I +    Q+MEMGF ++ I+ A+K L+           E++++ +L     D  ++ +                 +  +   D  S   V D L    P   + +  V   + + Y      D  +NDD A                          N++    V C   + E++ GD G ++  D D + D      W +   T     ++I +   P  S    I IGD+V            PA+T+     G V      +V+  +   D  +IVDFP        +S+++LV    H   C  C   PI+ P +KCK C +   C NC
Sbjct: 2341 ATQPSPIKAIFDRQEMEAA--ALAVCQYLAVESAHPSSPTFEESSSSEATTPVTVQHVRPPKQKKQKTSPIP---------------PLPIVL----QLMEMGFPRKNIEFALKSLSGTTGSASGIPVEALVSWLLD--HPDVHVTEL-----------------SDADTVSDEYSDEEVLDELVEAEPAFSVPAGAVV-TESQTYK--KRSDFQSNDDYAMYVRE---------------------NIQVGMMVKCCRTYEEVYDGDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHIELLGFPPQSSPSHIKIGDKVRVK---------PAVTTPKYKWGSVTHRSVGVVKFSANGKD--VIVDFPQQSHWTGLLSEMELV-PSVHPGVCDGCQMFPINGPRFKCKNCDDFDFCDNC 2687

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Medaka
Match: herc4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4 [Source:NCBI gene;Acc:101174618])

HSP 1 Score: 159.073 bits (401), Expect = 4.039e-38
Identity = 103/325 (31.69%), Postives = 177/325 (54.46%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG--HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD--LDSF 10552
            G++S G+LG+G    I  E+++ P++ E      +  V    G RH   L ++G  ++ G  D G+LGH    K   P ++     + +V ++CG SH+ A+   G +++WGLG  G+LG  + +  +R+ P  +KSL D +V QVACG     +LAL+    ++SWG   +G+LG G +   + +PQ ++ +      QI  G   SFALT +G V+ WG+  + +LG         P  ++ L+  ++++++ G  H  A+T  G V+++G   +GQ G+ +  + + P  V  LM N +  +ACG  H++A+T S   +DSF
Sbjct:    5 GNASYGQLGLGG---IDEEIVVEPRKCEFFHGKRVRDVGC--GRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRK--KPEQVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRV-PRNIKSLSDVQVAQVACGY--WHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSGKMDSF 319

HSP 2 Score: 139.043 bits (349), Expect = 6.639e-32
Identity = 119/398 (29.90%), Postives = 189/398 (47.49%), Query Frame = 2

Query: 12455 WGHNHRGQLG--GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHG-NGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT-EDGEVYSWGDNDEGQLGDGTTTTNSRPRIIES-----------LTGKG--INRVACGSAHTLAWTTVSGNK 13597
            WG+   GQLG  G++   +  P  CE     R R +  G +    +  DG VY  G  + G+L  G  +S + P  V  L+ +I+  VA++ G  H LAL + G V++WG   D +LGL+      E +  P  +KSL   ++  +A G  HS A+S+ G +++WG+ RYG+LG G  G     P+ +++L+G     +A G   +  L ++             +V+ WG   +G+LG    +    P  ++ L    VI + CG   +  LT  G V+T+G G Y +LGH S NH   P KV +L    +  +ACG  H +  T   G++ S+G    GQLG  +T     P  ++              G+   +NR+  G   + A  + S N+
Sbjct:    4 WGNASYGQLGLGGIDEEIVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQL--GHEKSRKKPEQVVALDAQII--VALSCGESHTLALNDKGQVFSWGLGSDGQLGLN---NFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSG------------AVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSGKMDSFGLGGNGQLGTRSTCNRKSPAPVKGPWASSSASSDSDIGESCVVNRIYAGGDQSFAHYSSSSNE 382

HSP 3 Score: 118.242 bits (295), Expect = 1.338e-25
Identity = 67/215 (31.16%), Postives = 116/215 (53.95%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSK-VKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALT 10063
            +++ WGL    QLG     + +++P   ++LS++    ++ G      +++ G ++  G +  G+LG+G    +T + I  P+ L++L      ++A  +GG H+ ALT +G  F WG    G+LG N      +P  +K  + +RV+ ++CG  H+AA+   G ++T+G G YG+LGH  T   ++P  V  L    V Q+ACG +   TLA T
Sbjct:  104 QVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLG----MTGQSISVPQHLQSLQGIPFAQIA--AGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQ--HTLAFT 310

HSP 4 Score: 98.2117 bits (243), Expect = 1.995e-19
Identity = 73/258 (28.29%), Postives = 108/258 (41.86%), Query Frame = 2

Query: 9914 LYTWGLGDYGRLGHG--DTAMRLHPELVKSLRDYKVVQVACGSR-------------------------------------DAQ-----------TLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWT 10531
            +  WG   YG+LG G  D  + + P   +     +V  V CG R                                     DAQ           TLAL     V+SWG G  G+LG      C+ +P+ I+ +S   V Q+ CG   S AL++ G +++WG+  Y +LG G T + I  P  ++ L+      +A G  H  A+T  G V+ WG N  GQ G         P L+ AL   ++ +++CG  H+ A T
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALT 258

HSP 5 Score: 91.2781 bits (225), Expect = 2.773e-17
Identity = 55/142 (38.73%), Postives = 79/142 (55.63%), Query Frame = 2

Query: 1604 RVIDVDANIY------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR-PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +V+ +DA I        SH LA+ + GQV+SWG  + G+LG  + ++  R P  I + S   +QV QVACG  HSL L++ G I+S G+N  GQLG G +  + + +      L G+   QIA  G  S  L+  GA+F WG
Sbjct:   77 QVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLS--DVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLG-MTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWG 215

HSP 6 Score: 83.1889 bits (204), Expect = 6.712e-15
Identity = 66/240 (27.50%), Postives = 108/240 (45.00%), Query Frame = 2

Query: 1295 HKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDR-KRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            H  + +   T  T   NDL +   E    +P+++   L+ +  I  + C    T  L+D G ++     SD  +         +N+  +C++    +K  S  +V  V    +  H LA+++ G ++SWG N  G+LG G T      P  + +     +   Q+A G  HS  LT SG ++  GRN  GQLG  D  DR  P  + A  L    V  I+     +  L+ +G +FT+G+
Sbjct:   45 HTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQV-VALDAQI-IVALSCGESHTLALNDKGQVFSWGLGSDGQL--------GLNNFEECIRVPRNIKSLSDVQVAQVACGYW--HSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQ--GIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKA--LRSQRVIYISCGEDHTAALTKEGGVFTFGA 268

HSP 7 Score: 80.4925 bits (197), Expect = 4.599e-14
Identity = 70/215 (32.56%), Postives = 113/215 (52.56%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSK-IKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGST-ESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCIT 13081
            +V+SWG    GQLG     + I+VP   + LS ++  Q+  G      +S  G +++ G    G+LG+G T +S+  P  +  L+     ++A  +GG H  AL  +G V+ WG  +  +LGL+       D   P L+K+L    +I I+ G  H+AA+++ G ++T+G G YG+LGH + + +  P+ V  L G  V  +ACG     TL  T
Sbjct:  104 QVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIA--AGGAHSFALTLSGAVFGWGRNKFGQLGLN----DTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGR--QHTLAFT 310

HSP 8 Score: 72.4034 bits (176), Expect = 1.380e-11
Identity = 37/116 (31.90%), Postives = 61/116 (52.59%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLS 1981
             +H  A+T +G V+ WG N  G+LG  DT DR  P ++        +V  ++CGE+H+  LT+ G +++ G    GQLGH        P ++   +L+G +V QIA     ++  +
Sbjct:  199 GAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRS--QRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVF--ELMGNVVTQIACGRQHTLAFT 310

HSP 9 Score: 70.0922 bits (170), Expect = 7.910e-11
Identity = 93/329 (28.27%), Postives = 146/329 (44.38%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKT--NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELEN---LQIPYSVTAIDGKEVNLNIETSGAIFVNASNR----NSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVK-SDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDI 15103
            KV  +GE   D GG   E    I  EL +     F    D     L  +++KT  +   F  +G + G+AI     + L     ++K L  +    +DL+    D+  SL  L    E ++E    L    +       EV+  +     + VN  NR    N+Y+D V N  +    + C +   G   V    +L LF   EL+ +V GN +   + L+  T Y+G   ++   I  FWE+  E+  E +  FL F+ G  R+P  +  ++  + VIQ        + +LP A+TCF LL LP Y+S   L+EKLL AI   +  ++
Sbjct:  729 KVIFVGEDAVDAGGVRKEFFLLIMKELLDPKYGMFRYHEDSR---LIWFSNKTFEDIDLFNLIGLICGLAIYNLTIVELHFPLALYKKLLKKKPTLDDLKELMPDVGRSLQQLLDYTEDDVEETFCLNFTITEENYGATEVHELVPNGEELSVNKGNRQDFVNAYVDYVFNSSVASLFE-CFY--SGFHKVCGGKVLELFQPSELQAMVIGNTNYDWTELEKSTEYKGEYWAEHPTIKLFWEVFHELPLEKKKQFLLFLTGSDRIP--ILGMKSLKLVIQ---PTGGGEQFLPVAHTCFNLLDLPKYTSPEALREKLLQAIDHNRGFNL 1046

HSP 10 Score: 68.1662 bits (165), Expect = 2.851e-10
Identity = 47/171 (27.49%), Postives = 80/171 (46.78%), Query Frame = 2

Query: 1679 WGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL----QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN--EIDQIQVHDSTYS-----VLLKSGSVYTW 2158
            WG  + G+LG G   +     I+    +C      +V+ V CG  H+  L + G +Y+CG N +GQLGH   K R  P ++ A D    ++  ++     ++ L++ G +F+WG   D  +  L+N+    E C+   RN   +  +QV            L K G +++W
Sbjct:    4 WGNASYGQLGLGGIDEE----IVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGH--EKSRKKPEQVVALD--AQIIVALSCGESHTLALNDKGQVFSWGLGSDG-QLGLNNF----EECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSW 161

HSP 11 Score: 62.7734 bits (151), Expect = 1.300e-8
Identity = 39/125 (31.20%), Postives = 59/125 (47.20%), Query Frame = 2

Query: 12431 ASGLEVWSWGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLG 12802
            + G  ++SWG N  GQLG G+ G  I VP   + L  +   QI  G    F +++ G V+  G    G+LG+  T     P L+  L  + V+ ++   G  H  AL   G V+ +G     +LG
Sbjct:  153 SKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISC--GEDHTAALTKEGGVFTFGAGGYGQLG 275

HSP 12 Score: 54.299 bits (129), Expect = 4.745e-6
Identity = 47/192 (24.48%), Postives = 79/192 (41.15%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSE---NTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTK-NGETFSWGEGDDGKLGHNSRLKLNYPRKIK 9838
            I++W Q R  +L   M   +     +  +L       +       F   +   ++ WG N   QLG   T+    P L +AL     + IS G      +T+ G V+  G    G+LG  S         + P+++  L    + ++A   G +H +A T  +G+  S+G G +G+LG  S      P  +K
Sbjct:  158 IFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNH-----EVNPRKVFELMGNVVTQIAC--GRQHTLAFTPSSGKMDSFGLGGNGQLGTRSTCNRKSPAPVK 342

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Medaka
Match: herc4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4 [Source:NCBI gene;Acc:101174618])

HSP 1 Score: 159.073 bits (401), Expect = 5.108e-38
Identity = 103/325 (31.69%), Postives = 177/325 (54.46%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG--HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASD--LDSF 10552
            G++S G+LG+G    I  E+++ P++ E      +  V    G RH   L ++G  ++ G  D G+LGH    K   P ++     + +V ++CG SH+ A+   G +++WGLG  G+LG  + +  +R+ P  +KSL D +V QVACG     +LAL+    ++SWG   +G+LG G +   + +PQ ++ +      QI  G   SFALT +G V+ WG+  + +LG         P  ++ L+  ++++++ G  H  A+T  G V+++G   +GQ G+ +  + + P  V  LM N +  +ACG  H++A+T S   +DSF
Sbjct:    5 GNASYGQLGLGG---IDEEIVVEPRKCEFFHGKRVRDVGC--GRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRK--KPEQVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRV-PRNIKSLSDVQVAQVACGY--WHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSGKMDSF 319

HSP 2 Score: 138.272 bits (347), Expect = 1.186e-31
Identity = 112/354 (31.64%), Postives = 174/354 (49.15%), Query Frame = 2

Query: 12455 WGHNHRGQLG--GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHG-NGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT-EDGEVYSWGDNDEGQLGDGTTTTNSRP 13504
            WG+   GQLG  G++   +  P  CE     R R +  G +    +  DG VY  G  + G+L  G  +S + P  V  L+ +I+  VA++ G  H LAL + G V++WG   D +LGL+      E +  P  +KSL   ++  +A G  HS A+S+ G +++WG+ RYG+LG G  G     P+ +++L+G     +A G   +  L ++             +V+ WG   +G+LG    +    P  ++ L    VI + CG   +  LT  G V+T+G G Y +LGH S NH   P KV +L    +  +ACG  H +  T   G++ S+G    GQLG  +T     P
Sbjct:    4 WGNASYGQLGLGGIDEEIVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQL--GHEKSRKKPEQVVALDAQII--VALSCGESHTLALNDKGQVFSWGLGSDGQLGLN---NFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSG------------AVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSGKMDSFGLGGNGQLGTRSTCNRKSP 338

HSP 3 Score: 118.242 bits (295), Expect = 1.540e-25
Identity = 67/215 (31.16%), Postives = 116/215 (53.95%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCEATSK-VKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALT 10063
            +++ WGL    QLG     + +++P   ++LS++    ++ G      +++ G ++  G +  G+LG+G    +T + I  P+ L++L      ++A  +GG H+ ALT +G  F WG    G+LG N      +P  +K  + +RV+ ++CG  H+AA+   G ++T+G G YG+LGH  T   ++P  V  L    V Q+ACG +   TLA T
Sbjct:  104 QVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLG----MTGQSISVPQHLQSLQGIPFAQIA--AGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQ--HTLAFT 310

HSP 4 Score: 105.145 bits (261), Expect = 1.328e-21
Identity = 94/342 (27.49%), Postives = 156/342 (45.61%), Query Frame = 2

Query: 12614 GFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVA------------VNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDV--LTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDD-QPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXX-XICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            G  + G+LG+G            G++E+IVV+              V  G +H   L  +G VY  G  +  +LG +   +  E V  L   ++ +L   E   +A             ++++WG G  G+LG  N ++    P+ +++L    V  VACG     +L ++K             ++SWG   YG+LG G       +P  +++L+G    ++  G   S  LT SG V+ WG+  + +LG    N    P  +  L  +++I ++CG  H    T++G V+++G    GQLG  +T     PR +  L G  + ++ACG  HTLA+T  SG
Sbjct:    5 GNASYGQLGLG------------GIDEEIVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQIIVALSCGESHTLALNDKG--------QVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGY--WHSLALSKG----------GHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGRQHTLAFTPSSG 314

HSP 5 Score: 98.2117 bits (243), Expect = 2.048e-19
Identity = 73/258 (28.29%), Postives = 108/258 (41.86%), Query Frame = 2

Query: 9914 LYTWGLGDYGRLGHG--DTAMRLHPELVKSLRDYKVVQVACGSR-------------------------------------DAQ-----------TLALTSDFTVWSWXXXXXXXXXXXXXXXCL-IPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWT 10531
            +  WG   YG+LG G  D  + + P   +     +V  V CG R                                     DAQ           TLAL     V+SWG G  G+LG      C+ +P+ I+ +S   V Q+ CG   S AL++ G +++WG+  Y +LG G T + I  P  ++ L+      +A G  H  A+T  G V+ WG N  GQ G         P L+ AL   ++ +++CG  H+ A T
Sbjct:    1 MLCWGNASYGQLGLGGIDEEIVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALT 258

HSP 6 Score: 90.8929 bits (224), Expect = 3.453e-17
Identity = 55/142 (38.73%), Postives = 79/142 (55.63%), Query Frame = 2

Query: 1604 RVIDVDANIY------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR-PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWG 2008
            +V+ +DA I        SH LA+ + GQV+SWG  + G+LG  + ++  R P  I + S   +QV QVACG  HSL L++ G I+S G+N  GQLG G +  + + +      L G+   QIA  G  S  L+  GA+F WG
Sbjct:   77 QVVALDAQIIVALSCGESHTLALNDKGQVFSWGLGSDGQLGLNNFEECIRVPRNIKSLS--DVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLG-MTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWG 215

HSP 7 Score: 83.1889 bits (204), Expect = 6.990e-15
Identity = 66/240 (27.50%), Postives = 108/240 (45.00%), Query Frame = 2

Query: 1295 HKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDR-KRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGS 2011
            H  + +   T  T   NDL +   E    +P+++   L+ +  I  + C    T  L+D G ++     SD  +         +N+  +C++    +K  S  +V  V    +  H LA+++ G ++SWG N  G+LG G T      P  + +     +   Q+A G  HS  LT SG ++  GRN  GQLG  D  DR  P  + A  L    V  I+     +  L+ +G +FT+G+
Sbjct:   45 HTAFLLEDGTVYTCGCNDLGQLGHEKSRKKPEQV-VALDAQI-IVALSCGESHTLALNDKGQVFSWGLGSDGQL--------GLNNFEECIRVPRNIKSLSDVQVAQVACGYW--HSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQ--GIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKA--LRSQRVIYISCGEDHTAALTKEGGVFTFGA 268

HSP 8 Score: 80.1073 bits (196), Expect = 5.765e-14
Identity = 70/215 (32.56%), Postives = 113/215 (52.56%), Query Frame = 2

Query: 12443 EVWSWGHNHRGQLGGVEGSK-IKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGST-ESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCIT 13081
            +V+SWG    GQLG     + I+VP   + LS ++  Q+  G      +S  G +++ G    G+LG+G T +S+  P  +  L+     ++A  +GG H  AL  +G V+ WG  +  +LGL+       D   P L+K+L    +I I+ G  H+AA+++ G ++T+G G YG+LGH + + +  P+ V  L G  V  +ACG     TL  T
Sbjct:  104 QVFSWGLGSDGQLGLNNFEECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIA--AGGAHSFALTLSGAVFGWGRNKFGQLGLN----DTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVFELMGNVVTQIACGR--QHTLAFT 310

HSP 9 Score: 72.4034 bits (176), Expect = 1.602e-11
Identity = 37/116 (31.90%), Postives = 61/116 (52.59%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLS 1981
             +H  A+T +G V+ WG N  G+LG  DT DR  P ++        +V  ++CGE+H+  LT+ G +++ G    GQLGH        P ++   +L+G +V QIA     ++  +
Sbjct:  199 GAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRS--QRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNHEVNPRKVF--ELMGNVVTQIACGRQHTLAFT 310

HSP 10 Score: 70.0922 bits (170), Expect = 6.948e-11
Identity = 93/329 (28.27%), Postives = 146/329 (44.38%), Query Frame = 2

Query: 14147 KVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKT--NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELEN---LQIPYSVTAIDGKEVNLNIETSGAIFVNASNR----NSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVK-SDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDI 15103
            KV  +GE   D GG   E    I  EL +     F    D     L  +++KT  +   F  +G + G+AI     + L     ++K L  +    +DL+    D+  SL  L    E ++E    L    +       EV+  +     + VN  NR    N+Y+D V N  +    + C +   G   V    +L LF   EL+ +V GN +   + L+  T Y+G   ++   I  FWE+  E+  E +  FL F+ G  R+P  +  ++  + VIQ        + +LP A+TCF LL LP Y+S   L+EKLL AI   +  ++
Sbjct:  743 KVIFVGEDAVDAGGVRKEFFLLIMKELLDPKYGMFRYHEDSR---LIWFSNKTFEDIDLFNLIGLICGLAIYNLTIVELHFPLALYKKLLKKKPTLDDLKELMPDVGRSLQQLLDYTEDDVEETFCLNFTITEENYGATEVHELVPNGEELSVNKGNRQDFVNAYVDYVFNSSVASLFE-CFY--SGFHKVCGGKVLELFQPSELQAMVIGNTNYDWTELEKSTEYKGEYWAEHPTIKLFWEVFHELPLEKKKQFLLFLTGSDRIP--ILGMKSLKLVIQ---PTGGGEQFLPVAHTCFNLLDLPKYTSPEALREKLLQAIDHNRGFNL 1060

HSP 11 Score: 68.1662 bits (165), Expect = 3.091e-10
Identity = 46/171 (26.90%), Postives = 80/171 (46.78%), Query Frame = 2

Query: 1679 WGTNTSGKLGQGDTKDRKRPTIIDTFSRCHL----QVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRN-------EIDQIQVHDSTYSVLLKSGSVYTW 2158
            WG  + G+LG G   +     I+    +C      +V+ V CG  H+  L + G +Y+CG N +GQLGH   K R  P ++ A D    ++  ++     ++ L++ G +F+WG   D  +  L+N+    E C+   RN       ++ Q+         L K G +++W
Sbjct:    4 WGNASYGQLGLGGIDEE----IVVEPRKCEFFHGKRVRDVGCGRRHTAFLLEDGTVYTCGCNDLGQLGH--EKSRKKPEQVVALD--AQIIVALSCGESHTLALNDKGQVFSWGLGSDG-QLGLNNF----EECIRVPRNIKSLSDVQVAQVACGYWHSLALSKGGHIFSW 161

HSP 12 Score: 62.3882 bits (150), Expect = 1.373e-8
Identity = 39/125 (31.20%), Postives = 59/125 (47.20%), Query Frame = 2

Query: 12431 ASGLEVWSWGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLG 12802
            + G  ++SWG N  GQLG G+ G  I VP   + L  +   QI  G    F +++ G V+  G    G+LG+  T     P L+  L  + V+ ++   G  H  AL   G V+ +G     +LG
Sbjct:  153 SKGGHIFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISC--GEDHTAALTKEGGVFTFGAGGYGQLG 275

HSP 13 Score: 53.9138 bits (128), Expect = 5.403e-6
Identity = 47/192 (24.48%), Postives = 79/192 (41.15%), Query Frame = 2

Query: 9275 IYNWRQARLNKLRFQMNSNTEDPTTNSDTLSE---NTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTK-NGETFSWGEGDDGKLGHNSRLKLNYPRKIK 9838
            I++W Q R  +L   M   +     +  +L       +       F   +   ++ WG N   QLG   T+    P L +AL     + IS G      +T+ G V+  G    G+LG  S         + P+++  L    + ++A   G +H +A T  +G+  S+G G +G+LG  S      P  +K
Sbjct:  158 IFSWGQNRYGQLGLGMTGQSISVPQHLQSLQGIPFAQIAAGGAHSFALTLSGAVFGWGRNKFGQLGLNDTNDRCFPALLKALRSQRVIYISCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTNH-----EVNPRKVFELMGNVVTQIAC--GRQHTLAFTPSSGKMDSFGLGGNGQLGTRSTCNRKSPAPVK 342

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Medaka
Match: herc3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:NCBI gene;Acc:101155493])

HSP 1 Score: 151.754 bits (382), Expect = 5.956e-36
Identity = 96/318 (30.19%), Postives = 169/318 (53.14%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG--HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXC-LIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            G++ +G+LGIG + +   E    P+         + +VA   GG+H + L ++G  ++ G    G+LGH+     N P  +     +++  V+CG +HS A+   G ++ WG GD G+LG    +TA+R+ P L+K L D+ + QV CG++    +AL+ D  +++WG    G+LG G      L P  ++ ++   + QI  G    FAL+ +G V+ WGK    +LG    +    P  I+ L+  ++V+++ G  H  A+T  G ++++GD   GQ G+G+    + P  V  LM  +++ + CG  H++A+  S
Sbjct:    5 GNARDGQLGIGVEGNPVFE----PRICHVFSGRGLKEVAC--GGQHTLFLLQDGSVYTCGSNSCGQLGHDK--AGNSPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRI-PRLLKKLCDHSISQVVCGNQ--HCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPS 311

HSP 2 Score: 145.976 bits (367), Expect = 4.077e-34
Identity = 110/359 (30.64%), Postives = 170/359 (47.35%), Query Frame = 2

Query: 9506 ALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLG-HNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG--HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLA-VTDRGQVYSWGDNDHGQQGNGTVTYNMRP----------TLVSALMDNKIAHVACGSSHSVAWTASD 10540
             L E+ C    GG  +LF + + G VY  G +S G+LG     +        P+ + ALD   I  V+   G  H++A+ + G+ F WG GD G+LG   +   +  PR +K      +  V CG+ H  A+   G L+TWG    G+LG   G+T+ +L P  VKSL    + Q+  G      L+L+    V+ WG    G+LG        +P  I+ +    V+ I CG + + ALT++G ++T+G G   +LGHG+  +   P ++ +L  T++  +  G  H LA V   G VY++G N HGQ G G +     P           L   L    +  + CG  HS    +S+
Sbjct:   34 GLKEVAC----GGQHTLF-LLQDGSVYTCGSNSCGQLGHDKAGN-------SPELVGALDTQKITMVSC--GRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETS-KLSPSPVKSLAGIPLAQITAGGDHCFALSLSG--AVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFGCNSHGQLGTGILADLRSPHPVKNDFLTLNLRKDLRKYTVIKIICGGDHSFLMYSSE 375

HSP 3 Score: 131.724 bits (330), Expect = 1.024e-29
Identity = 113/386 (29.27%), Postives = 182/386 (47.15%), Query Frame = 2

Query: 12455 WGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQII-GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPF-PKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT-EDGEVYSWGDNDEGQLGDGTTTTNSRPRIIES----------LTGKGINRVACGSAHTL 13570
            WG+   GQLG GVEG+ +  P +C   S    +++  GG+ +LF++  DG VY  G  + G+LG    ++  +P LV  L+ + +  V+   G  H +A+   G V+ WG  +  +LGL+        V  P L+K L    I  +  G  H  A+SR G+L+TWG+   G+LG G G+     P  V++L G  +  +  G      L ++             +V+ WG    G+LG        +P  I+ L    V+ + CG + +  LT SG ++T+G G   +LGHGS N+   P +V +L   ++  + CG  H +      G VY++G N  GQLG G       P  +++          L    + ++ CG  H+ 
Sbjct:    4 WGNARDGQLGIGVEGNPVFEPRICHVFSGRGLKEVACGGQHTLFLLQ-DGSVYTCGSNSCGQLG--HDKAGNSPELVGALDTQKITMVSC--GRAHSVAVNEQGQVFVWGAGDGGQLGLETAETA---VRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIPLAQITAGGDHCFALSLSG------------AVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFGCNSHGQLGTGILADLRSPHPVKNDFLTLNLRKDLRKYTVIKIICGGDHSF 369

HSP 4 Score: 124.02 bits (310), Expect = 2.408e-27
Identity = 88/282 (31.21%), Postives = 147/282 (52.13%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCE-ATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALT-SDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLS----------NVIQIECGAQSSFALTENGQ 10231
            +++VWG  D  QLG E A + V++P L + L +     +  G++    ++R G+++  G +S+G+LG+G     T++  + P  +++L    + ++   +GG H  AL+ +G  F WG+   G+LG N +     P  IK+ + +RVV ++CG  H+AA+   G L+T+G G  G+LGHG +   L P  V  L   +V Q+ CG     TLA   S  TV+++G    G+LG G  +    P  ++   L+           VI+I CG   SF +  + Q
Sbjct:  103 QVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGE--TSK--LSPSPVKSLAGIPLAQIT--AGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRH--HTLAFVPSSGTVYAFGCNSHGQLGTGILADLRSPHPVKNDFLTLNLRKDLRKYTVIKIICGGDHSFLMYSSEQ 376

HSP 5 Score: 107.071 bits (266), Expect = 3.138e-22
Identity = 94/329 (28.57%), Postives = 160/329 (48.63%), Query Frame = 2

Query: 12614 GFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQP-FPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKL-PMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSG 13591
            G   +G+LGIG     V  P +      + + +VA   GG+H L L  +G VY  G     +LG D   + G    +P LV +L   +I  ++ G +HS A++  G+++ WG G  G+LG    +     P++++ L  + +  V CG+      CI  + D ++        ++WG    G+LG G  +  KL P  +++L G  + ++  G      L+ SG V+ WGK    +LG         P  +  L  ++++ ++CG  H    T+ G ++++GD   GQLG G++     PR +  L G  ++++ CG  HTLA+   SG
Sbjct:    5 GNARDGQLGIGVEGNPVFEPRICHVFSGRGLKEVAC--GGQHTLFLLQDGSVYTCGSNSCGQLGHD---KAGN---SPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQH----CIALSRDGQL--------FTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSG 313

HSP 6 Score: 87.4261 bits (215), Expect = 3.969e-16
Identity = 71/233 (30.47%), Postives = 122/233 (52.36%), Query Frame = 2

Query: 12368 QIVGWLKSRPDAWKKCWPIDSASGLE---VWSWGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQ-TPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            ++VG L ++      C    S +  E   V+ WG    GQLG     + +++P L + L      Q++ G Q    +S DG+++  G  ++G+LG+G  E+ + +P  V  L    +    + +GG HC AL  +G V+ WG  +  +LGL+ +    +D   P  +K L    ++ I+ G  H+AA+++SG L+T+G G  G+LGHG+ +++  P+ V  L G  V  + CG
Sbjct:   75 ELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAG--IPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDK----QDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCG 301

HSP 7 Score: 84.3445 bits (207), Expect = 3.427e-15
Identity = 44/124 (35.48%), Postives = 71/124 (57.26%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMC-LSNDGAIFTWG 2008
            H  A++ +G V+ WG N +G+LG  D +DR  P  I  F R   +V  ++CG+EH+  LT+SG +++ G    GQLGHG   +  LP R+   +L+G  V QI    H ++  + + G ++ +G
Sbjct:  200 HCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIK-FLRSQ-RVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVM--ELMGTEVSQITCGRHHTLAFVPSSGTVYAFG 319

HSP 8 Score: 79.7221 bits (195), Expect = 7.947e-14
Identity = 52/177 (29.38%), Postives = 83/177 (46.89%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR-PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEY--RNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +H +AV E GQV+ WG    G+LG    +   R P ++     C   + QV CG +H + L++ G +++ G+N  GQLG G  +   L      S L G+ + QI   G     LS  GA+F WG      +  L++   +   C  ++     +  I   D   + L KSG ++T+
Sbjct:   93 AHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKL--CDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKS-LAGIPLAQITAGGDHCFALSLSGAVFGWGKN-KAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTF 265

HSP 9 Score: 76.2554 bits (186), Expect = 8.679e-13
Identity = 52/179 (29.05%), Postives = 87/179 (48.60%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIE----TCVNEYRNEIDQIQV-HDSTYSVLLKSGSVYTW 2158
            H +A++  GQ+++WG N+SG+LG G  +  K  P+ + + +   + + Q+  G +H   L+ SG ++  G+N  GQLG  D +DR +P  I    L    V  I+     +  L+  G +FT+G   D  R  L + S   E      +     E+ QI      T + +  SG+VY +
Sbjct:  147 HCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAG--IPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKF--LRSQRVVYISCGDEHTAALTKSGGLFTFG---DGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAF 318

HSP 10 Score: 67.0106 bits (162), Expect = 6.031e-10
Identity = 50/172 (29.07%), Postives = 76/172 (44.19%), Query Frame = 2

Query: 1679 WGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVL----VKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYR-------NEIDQIQVHDSTYSVLLKSGSVYTW 2158
            WG    G+LG G +      P I   FS   L  K+VACG +H+L L Q G +Y+CG N  GQLGH    +        + +L+G L    +  ++     S+ ++  G +F WG+  D  +  L       ET V   R       + I Q+   +     L + G ++TW
Sbjct:    4 WGNARDGQLGIGVEGNPVFEPRICHVFSGRGL--KEVACGGQHTLFLLQDGSVYTCGSNSCGQLGHDKAGN--------SPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAG-DGGQLGLET----AETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTW 160

HSP 11 Score: 57.7658 bits (138), Expect = 3.554e-7
Identity = 61/232 (26.29%), Postives = 92/232 (39.66%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITA--SDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDN----CRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK----YCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRT 2305
            H L + + G VY+ G+N+ G+LG    K    P ++        ++  V+CG  HS+ + + G ++  G    GQLG   ++     +RI      L    + Q+       + LS DG +FTWG          +   S  SP     +      + QI         L  SG+V+ W K         +K D   P     L+ Q   V  IS GD     L KSG + T
Sbjct:   44 HTLFLLQDGSVYTCGSNSCGQLGH--DKAGNSPELVGALDT--QKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLG---LETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGI--PLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQ--RVVYISCGDEHTAALTKSGGLFT 264

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Medaka
Match: herc3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:NCBI gene;Acc:101155493])

HSP 1 Score: 151.369 bits (381), Expect = 1.017e-35
Identity = 96/318 (30.19%), Postives = 169/318 (53.14%), Query Frame = 2

Query: 9593 GDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG--HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXC-LIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            G++ +G+LGIG + +   E    P+         + +VA   GG+H + L ++G  ++ G    G+LGH+     N P  +     +++  V+CG +HS A+   G ++ WG GD G+LG    +TA+R+ P L+K L D+ + QV CG++    +AL+ D  +++WG    G+LG G      L P  ++ ++   + QI  G    FAL+ +G V+ WGK    +LG    +    P  I+ L+  ++V+++ G  H  A+T  G ++++GD   GQ G+G+    + P  V  LM  +++ + CG  H++A+  S
Sbjct:    5 GNARDGQLGIGVEGNPVFE----PRICHVFSGRGLKEVAC--GGQHTLFLLQDGSVYTCGSNSCGQLGHDK--AGNSPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRI-PRLLKKLCDHSISQVVCGNQ--HCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPS 311

HSP 2 Score: 143.28 bits (360), Expect = 2.825e-33
Identity = 102/316 (32.28%), Postives = 158/316 (50.00%), Query Frame = 2

Query: 9506 ALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLG-HNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLG--HGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLA-VTDRGQVYSWGDNDHGQQGNGTVT 10441
             L E+ C    GG  +LF + + G VY  G +S G+LG     +        P+ + ALD   I  V+   G  H++A+ + G+ F WG GD G+LG   +   +  PR +K      +  V CG+ H  A+   G L+TWG    G+LG   G+T+ +L P  VKSL    + Q+  G      L+L+    V+ WG    G+LG        +P  I+ +    V+ I CG + + ALT++G ++T+G G   +LGHG+  +   P ++ +L  T++  +  G  H LA V   G VY++G N HGQ G G + 
Sbjct:   34 GLKEVAC----GGQHTLF-LLQDGSVYTCGSNSCGQLGHDKAGN-------SPELVGALDTQKITMVSC--GRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETS-KLSPSPVKSLAGIPLAQITAGGDHCFALSLSG--AVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFGCNSHGQLGTGILA 332

HSP 3 Score: 134.42 bits (337), Expect = 1.480e-30
Identity = 110/359 (30.64%), Postives = 174/359 (48.47%), Query Frame = 2

Query: 12455 WGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQII-GGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPF-PKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCT-EDGEVYSWGDNDEGQLGDGTTTTNSRPRIIES 13519
            WG+   GQLG GVEG+ +  P +C   S    +++  GG+ +LF++  DG VY  G  + G+LG    ++  +P LV  L+ + +  V+   G  H +A+   G V+ WG  +  +LGL+        V  P L+K L    I  +  G  H  A+SR G+L+TWG+   G+LG G G+     P  V++L G  +  +  G             D    L  + +V+ WG    G+LG        +P  I+ L    V+ + CG + +  LT SG ++T+G G   +LGHGS N+   P +V +L   ++  + CG  H +      G VY++G N  GQLG G       P  +++
Sbjct:    4 WGNARDGQLGIGVEGNPVFEPRICHVFSGRGLKEVACGGQHTLFLLQ-DGSVYTCGSNSCGQLG--HDKAGNSPELVGALDTQKITMVSC--GRAHSVAVNEQGQVFVWGAGDGGQLGLET---AETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIPLAQITAGG------------DHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAFGCNSHGQLGTGILADLRSPHPVKN 342

HSP 4 Score: 123.25 bits (308), Expect = 4.793e-27
Identity = 73/224 (32.59%), Postives = 124/224 (55.36%), Query Frame = 2

Query: 9422 KIYVWGLNDKDQLGCE-ATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALT-SDFTVWSW 10087
            +++VWG  D  QLG E A + V++P L + L +     +  G++    ++R G+++  G +S+G+LG+G     T++  + P  +++L    + ++   +GG H  AL+ +G  F WG+   G+LG N +     P  IK+ + +RVV ++CG  H+AA+   G L+T+G G  G+LGHG +   L P  V  L   +V Q+ CG     TLA   S  TV+++
Sbjct:  103 QVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGE--TSK--LSPSPVKSLAGIPLAQIT--AGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRH--HTLAFVPSSGTVYAF 318

HSP 5 Score: 111.309 bits (277), Expect = 2.165e-23
Identity = 94/330 (28.48%), Postives = 160/330 (48.48%), Query Frame = 2

Query: 12614 GFGNNGRLGIG-STESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQP-FPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKL-PMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGN 13594
            G   +G+LGIG     V  P +      + + +VA   GG+H L L  +G VY  G     +LG D   + G    +P LV +L   +I  ++ G +HS A++  G+++ WG G  G+LG    +     P++++ L  + +  V CG+      CI  + D ++        ++WG    G+LG G  +  KL P  +++L G  + ++  G      L+ SG V+ WGK    +LG         P  +  L  ++++ ++CG  H    T+ G ++++GD   GQLG G++     PR +  L G  ++++ CG  HTLA+   SG 
Sbjct:    5 GNARDGQLGIGVEGNPVFEPRICHVFSGRGLKEVAC--GGQHTLFLLQDGSVYTCGSNSCGQLGHD---KAGN---SPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQH----CIALSRDGQL--------FTWGQNSSGQLGLGKGETSKLSPSPVKSLAGIPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGT 314

HSP 6 Score: 89.7373 bits (221), Expect = 6.535e-17
Identity = 71/233 (30.47%), Postives = 122/233 (52.36%), Query Frame = 2

Query: 12368 QIVGWLKSRPDAWKKCWPIDSASGLE---VWSWGHNHRGQLG-GVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQ-TPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACG 13051
            ++VG L ++      C    S +  E   V+ WG    GQLG     + +++P L + L      Q++ G Q    +S DG+++  G  ++G+LG+G  E+ + +P  V  L    +    + +GG HC AL  +G V+ WG  +  +LGL+ +    +D   P  +K L    ++ I+ G  H+AA+++SG L+T+G G  G+LGHG+ +++  P+ V  L G  V  + CG
Sbjct:   75 ELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAG--IPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDK----QDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCG 301

HSP 7 Score: 84.3445 bits (207), Expect = 3.237e-15
Identity = 44/124 (35.48%), Postives = 71/124 (57.26%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMC-LSNDGAIFTWG 2008
            H  A++ +G V+ WG N +G+LG  D +DR  P  I  F R   +V  ++CG+EH+  LT+SG +++ G    GQLGHG   +  LP R+   +L+G  V QI    H ++  + + G ++ +G
Sbjct:  200 HCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIK-FLRSQ-RVVYISCGDEHTAALTKSGGLFTFGDGSRGQLGHGSSNNELLPRRVM--ELMGTEVSQITCGRHHTLAFVPSSGTVYAFG 319

HSP 8 Score: 79.337 bits (194), Expect = 9.405e-14
Identity = 52/177 (29.38%), Postives = 83/177 (46.89%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKR-PTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEY--RNEIDQIQVHDSTYSVLLKSGSVYTW 2158
            +H +AV E GQV+ WG    G+LG    +   R P ++     C   + QV CG +H + L++ G +++ G+N  GQLG G  +   L      S L G+ + QI   G     LS  GA+F WG      +  L++   +   C  ++     +  I   D   + L KSG ++T+
Sbjct:   93 AHSVAVNEQGQVFVWGAGDGGQLGLETAETAVRIPRLLKKL--CDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKS-LAGIPLAQITAGGDHCFALSLSGAVFGWGKN-KAGQLGLNDKQDRAVPCHIKFLRSQRVVYISCGDEHTAALTKSGGLFTF 265

HSP 9 Score: 76.2554 bits (186), Expect = 9.503e-13
Identity = 52/179 (29.05%), Postives = 87/179 (48.60%), Query Frame = 2

Query: 1640 HVLAVTEAGQVYSWGTNTSGKLGQGDTKDRK-RPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIE----TCVNEYRNEIDQIQV-HDSTYSVLLKSGSVYTW 2158
            H +A++  GQ+++WG N+SG+LG G  +  K  P+ + + +   + + Q+  G +H   L+ SG ++  G+N  GQLG  D +DR +P  I    L    V  I+     +  L+  G +FT+G   D  R  L + S   E      +     E+ QI      T + +  SG+VY +
Sbjct:  147 HCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAG--IPLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKF--LRSQRVVYISCGDEHTAALTKSGGLFTFG---DGSRGQLGHGSSNNELLPRRVMELMGTEVSQITCGRHHTLAFVPSSGTVYAF 318

HSP 10 Score: 67.0106 bits (162), Expect = 5.647e-10
Identity = 50/172 (29.07%), Postives = 76/172 (44.19%), Query Frame = 2

Query: 1679 WGTNTSGKLGQG-DTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVL----VKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYR-------NEIDQIQVHDSTYSVLLKSGSVYTW 2158
            WG    G+LG G +      P I   FS   L  K+VACG +H+L L Q G +Y+CG N  GQLGH    +        + +L+G L    +  ++     S+ ++  G +F WG+  D  +  L       ET V   R       + I Q+   +     L + G ++TW
Sbjct:    4 WGNARDGQLGIGVEGNPVFEPRICHVFSGRGL--KEVACGGQHTLFLLQDGSVYTCGSNSCGQLGHDKAGN--------SPELVGALDTQKITMVSCGRAHSVAVNEQGQVFVWGAG-DGGQLGLET----AETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTW 160

HSP 11 Score: 60.8474 bits (146), Expect = 4.029e-8
Identity = 66/269 (24.54%), Postives = 116/269 (43.12%), Query Frame = 2

Query: 14291 YADK--TNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVN--ASNRNSYIDEVINYKIHE-FDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXX-XXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAI 15079
            ++DK      WF  +G + G+AI  +  + L     ++K L   S +  D               K +  TE  +LQ    +   +G++V      + A  +N     R  ++D  + Y   +  D+       G   V    +L+LF   EL  +V GN++     L+   +Y+G  S     +  + E+  E   E +  FL F+ G  R+P     + G E +  ++   +  + YLP A+TC+ LL +P Y +K IL+ +L  A+
Sbjct:  770 FSDKCFVEQNWFHLIGIICGLAIYNSTVVDLHFPLALYKKLLDVSPSLEDF--------------KELSPTEARSLQ---QLLDYEGRDVEGTFLLNFAYLLNLCVCFRKEFVDSYLRYVFSDSVDEQYSAFSSGFLKVCGGEILSLFQPSELMAMVVGNNNYNWEELEKNAVYKGEYSATHPTVKLFWEVFHEFPLEKKKQFLLFLTGSDRIP-----IHGMESLRIIIQSTTAEEHYLPVAHTCYNLLDMPRYQTKEILRRRLTQAV 1016

HSP 12 Score: 57.3806 bits (137), Expect = 5.639e-7
Identity = 61/234 (26.07%), Postives = 92/234 (39.32%), Query Frame = 2

Query: 1634 SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRIT--ASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDN----CRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK----YCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRT 2305
              H L + + G VY+ G+N+ G+LG    K    P ++        ++  V+CG  HS+ + + G ++  G    GQLG   ++     +RI      L    + Q+       + LS DG +FTWG          +   S  SP     +      + QI         L  SG+V+ W K         +K D   P     L+ Q   V  IS GD     L KSG + T
Sbjct:   42 GQHTLFLLQDGSVYTCGSNSCGQLGH--DKAGNSPELVGALDT--QKITMVSCGRAHSVAVNEQGQVFVWGAGDGGQLG---LETAETAVRIPRLLKKLCDHSISQVVCGNQHCIALSRDGQLFTWGQNSSGQLGLGKGETSKLSPSPVKSLAGI--PLAQITAGGDHCFALSLSGAVFGWGKNKAGQLGLNDKQDRAVPCHIKFLRSQ--RVVYISCGDEHTAALTKSGGLFT 264

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Planmine SMEST
Match: SMESG000054104.1 (SMESG000054104.1)

HSP 1 Score: 10064.9 bits (26117), Expect = 0.000e+0
Identity = 5160/5160 (100.00%), Postives = 5160/5160 (100.00%), Query Frame = 2

Query:   53 MLHSYDFKTLSNESNFYKLLNEDKEAVGKFFSHSDEITNKLKRQLEDCNYEFGYLNAESILINKLVKISKESSDLVKSVIISGDIQPQIELFHLIFQNTMETFITYQDHVDSKIQNSDNLTKEQLIPETHNLFRSYQGKATGGLLGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTDTLPFWSGVTEQTYQFLKNTVLCPSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLKHIIMLIQLSSGSKNYSHLTLTTGSDNGETMKPMITGQILSVLIRIAKFVKITTTNNNEITCARSTHLSSNPCLRLLDWMHLDNMKDDEPIDVDICLLNAAVYIMSCLDCLTIENQIAYSTWYKAHLVKHADSNVPNYKYENFLNTFCSSIEKSSHKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIKRNYILAWSLVKEKPKLTQPFILEVSIENXXXXXXXXXXIIVNFGTASDNENNVESRIESNNWLQYLLKINPNNKFELTEDRLCILVSSLHLLSIQLQKIVEEHLKIPNELLVQLKRDIINCCCGSISQMHSSIKHAAQMCLISGWKILFASQMEKLLGIYYTLQIAEPSESRYNLIVAMCLDTIDLKQFIHTLIELSTNIAGTVSQDLPNVEDVIETIVRYTFTNIRSQFXXXXXXXXXXXXXXXXXXXXXNKELFDCDPLNAPNIADLNDNDHSIMHKLFSFLSDLMRKIIFLLKESKPGQDSLQPTLKSLIGIYGKVLAQQSIETAEYCWLCISKSNITPKELIHTLNKSGFSRLLLNFIESMRWLLKSYLDSKSVLKSDYKLSKANWKSLNSSSNPMFHFDMLFKFSVNMREIVFAFKPLILLLDKINRLNESLLFVDSEDGSLPGWLYNPCSESLQKIDKVIFRSKDISESTDQLIVIDNRVYDLDRLLMDSREKFDEYLPNRNSKTIITDIVNKSIYRXXXXXXXXXCYCGEYIDDDSQPISYFDSDNEDYRQLYFIERMLLMLMSDVLLFHQTCCNLMKQSIGFKQLQEFPLALKQIVLKKKXXXXXXXXXXXXXXILSFSHMEEKERDEVEETNDMSGTGVINLNEDSNRKMITTCINLLMFGSASSLIGKGTSPIMTNILQWLRSDTYKTKNISKANSMLLLDNIQDSYLNSLFVLNLVALVKHVNLCEELANHIMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGKIRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAKKIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLLVNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDGPNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTLITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKLICRSAITDSIIERLWNCLLQAILGHCSEDMKSLFSAHSLNASPSKIKIMELSIIFRNMLRCSSPNRISARNFLFNAISQSLDQQMDNQIQLLGLFCIFSDIENRIYPGIAMSTVKRENEKKQQTYLGIVEEITMIENDKFXXXXXXASAADSCDSFVDWQRDYDIHDLTCDLQIDSSKILFPFEIMSSLTETESEVMSKFLLMLISNFYSSNENILTKTSSLQNVFKIMQLSTLMEFCEHNLTELWYPIYKSNDEVFRSALDMASRACSIKSSISVQELKKALSQLATNIYSGSEEKEPMGSNAKLTDFDYIENSMGIQRKEKKRKSSALSKIMKSKNPHKESRRDPLNINMDLQFQIMEMGFSKRQIQAAVKELARNGNLYLTSNPESIITTILSFQQDDYSLSPXXXXXXXXXXXXXXXXXSTGLNLTDDNSSCSTVCDHLQYMMPMHQLHSPTVSDNDDKIYDLYGNDDILTNDDEAFNAXXXXXXXXXXXXKPMTSDVEKNFNLKGEFNVVCVNNFGEIFVGDQGILSCDGDAIDGYCNVFWTKISKTISTEKLNIHIFTNPTMSIIIGDEVTFSESGIRFHSVPAMTSLSNGIVRQIVRLDSEDDDLKIIVDFPNCIGKVCNISDLKLVVKGQHKYQCQACLKSPISLPMYKCKICRNLYLCSNCXXXXXXXXXXXXLNITADEDAKKPKITNGNLFDDSGKVQTLSVTASVSKSELKQCLSFTNFSLIPQTMSRNIEYTSSNNHCLIKIAEGYRVHKIFMLISLSEFLLLPSHVIVKKGIKSKKLSTVYRAHVQSLKEDEFIINSSKYYSSGLKLMWLKIYQDKRKHQSTERVXXXXXXXXXXXXRTVFNAVKSFHIQLMENRVDAKSTAISNDILLKTIFSISDKNWSAEDIDTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKXXXXXXXXXXXXLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTCSQSTELTKKESDNLPSTANKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLLLVDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALNPDSLPCAESVPNLPRREINCXXXXXXXXXXPRIYIXXXXXXXXXXXXXXXXXXXTARAPNALFGSSPSPSDRYSIQRNNQYLVDDYMELINGVFDAPRFMDISLDTEVNXXXXXXXXXHPYGTITSLFRGLRDD 15532
            MLHSYDFKTLSNESNFYKLLNEDKEAVGKFFSHSDEITNKLKRQLEDCNYEFGYLNAESILINKLVKISKESSDLVKSVIISGDIQPQIELFHLIFQNTMETFITYQDHVDSKIQNSDNLTKEQLIPETHNLFRSYQGKATGGLLGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTDTLPFWSGVTEQTYQFLKNTVLCPSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLKHIIMLIQLSSGSKNYSHLTLTTGSDNGETMKPMITGQILSVLIRIAKFVKITTTNNNEITCARSTHLSSNPCLRLLDWMHLDNMKDDEPIDVDICLLNAAVYIMSCLDCLTIENQIAYSTWYKAHLVKHADSNVPNYKYENFLNTFCSSIEKSSHKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIKRNYILAWSLVKEKPKLTQPFILEVSIENLQLLSRLLSSIIVNFGTASDNENNVESRIESNNWLQYLLKINPNNKFELTEDRLCILVSSLHLLSIQLQKIVEEHLKIPNELLVQLKRDIINCCCGSISQMHSSIKHAAQMCLISGWKILFASQMEKLLGIYYTLQIAEPSESRYNLIVAMCLDTIDLKQFIHTLIELSTNIAGTVSQDLPNVEDVIETIVRYTFTNIRSQFLVPVVSSFKSSPGSFSSSVLKNKELFDCDPLNAPNIADLNDNDHSIMHKLFSFLSDLMRKIIFLLKESKPGQDSLQPTLKSLIGIYGKVLAQQSIETAEYCWLCISKSNITPKELIHTLNKSGFSRLLLNFIESMRWLLKSYLDSKSVLKSDYKLSKANWKSLNSSSNPMFHFDMLFKFSVNMREIVFAFKPLILLLDKINRLNESLLFVDSEDGSLPGWLYNPCSESLQKIDKVIFRSKDISESTDQLIVIDNRVYDLDRLLMDSREKFDEYLPNRNSKTIITDIVNKSIYRKELLKLLLECYCGEYIDDDSQPISYFDSDNEDYRQLYFIERMLLMLMSDVLLFHQTCCNLMKQSIGFKQLQEFPLALKQIVLKKKTDQSQTNNDTNTATILSFSHMEEKERDEVEETNDMSGTGVINLNEDSNRKMITTCINLLMFGSASSLIGKGTSPIMTNILQWLRSDTYKTKNISKANSMLLLDNIQDSYLNSLFVLNLVALVKHVNLCEELANHIMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGKIRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAKKIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLLVNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDGPNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTLITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKLICRSAITDSIIERLWNCLLQAILGHCSEDMKSLFSAHSLNASPSKIKIMELSIIFRNMLRCSSPNRISARNFLFNAISQSLDQQMDNQIQLLGLFCIFSDIENRIYPGIAMSTVKRENEKKQQTYLGIVEEITMIENDKFVVTTVVASAADSCDSFVDWQRDYDIHDLTCDLQIDSSKILFPFEIMSSLTETESEVMSKFLLMLISNFYSSNENILTKTSSLQNVFKIMQLSTLMEFCEHNLTELWYPIYKSNDEVFRSALDMASRACSIKSSISVQELKKALSQLATNIYSGSEEKEPMGSNAKLTDFDYIENSMGIQRKEKKRKSSALSKIMKSKNPHKESRRDPLNINMDLQFQIMEMGFSKRQIQAAVKELARNGNLYLTSNPESIITTILSFQQDDYSLSPVEDNDVEADDDNDEDDDSTGLNLTDDNSSCSTVCDHLQYMMPMHQLHSPTVSDNDDKIYDLYGNDDILTNDDEAFNADSSDDGISEDEEKPMTSDVEKNFNLKGEFNVVCVNNFGEIFVGDQGILSCDGDAIDGYCNVFWTKISKTISTEKLNIHIFTNPTMSIIIGDEVTFSESGIRFHSVPAMTSLSNGIVRQIVRLDSEDDDLKIIVDFPNCIGKVCNISDLKLVVKGQHKYQCQACLKSPISLPMYKCKICRNLYLCSNCHSKFQKSHKHKFLNITADEDAKKPKITNGNLFDDSGKVQTLSVTASVSKSELKQCLSFTNFSLIPQTMSRNIEYTSSNNHCLIKIAEGYRVHKIFMLISLSEFLLLPSHVIVKKGIKSKKLSTVYRAHVQSLKEDEFIINSSKYYSSGLKLMWLKIYQDKRKHQSTERVFSLDLFDESSSLRTVFNAVKSFHIQLMENRVDAKSTAISNDILLKTIFSISDKNWSAEDIDTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWGDGDFGKLGRGGSSGCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKNENDENENNDYNLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTCSQSTELTKKESDNLPSTANKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLLLVDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEIIDIAAGGSHSAAISRSGELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWGDGDYGKLGRGGFDICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDLLSSLMSLKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLIIIWFWEIMEEMTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALNPDSLPCAESVPNLPRREINCSQSSSSGSTSPRIYISNSSSSSSSSSQDDDSDASTARAPNALFGSSPSPSDRYSIQRNNQYLVDDYMELINGVFDAPRFMDISLDTEVNEDDDSSEDDHPYGTITSLFRGLRDD
Sbjct:    1 MLHSYDFKTLSNESNFYKLLNEDKEAVGKFFSHSDEITNKLKRQLEDCNYEFGYLNAESILINKLVKISKESSDLVKSVIISGDIQPQIELFHLIFQNTMETFITYQDHVDSKIQNSDNLTKEQLIPETHNLFRSYQGKATGGLLGNVLAKSGVKMMFIFMQRLWRVGNEMDVQNCVEVMRSAIEEIQEIPVAGFFNVSDNTDTLPFWSGVTEQTYQFLKNTVLCPSSNDMIIPKPIRDAALVLLLEMGLIYGNLSMQLKHIIMLIQLSSGSKNYSHLTLTTGSDNGETMKPMITGQILSVLIRIAKFVKITTTNNNEITCARSTHLSSNPCLRLLDWMHLDNMKDDEPIDVDICLLNAAVYIMSCLDCLTIENQIAYSTWYKAHLVKHADSNVPNYKYENFLNTFCSSIEKSSHKLYFIRLSTSLTLMKNDLRESKFEIVEIRPDKLPRELNEKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIYSSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLKYCTECNKSDDIQPELDTVLKYQVDNVSMISKGDGEFYFLDKSGIIRTKKSMKITDHKFSGFGFIKRNYILAWSLVKEKPKLTQPFILEVSIENLQLLSRLLSSIIVNFGTASDNENNVESRIESNNWLQYLLKINPNNKFELTEDRLCILVSSLHLLSIQLQKIVEEHLKIPNELLVQLKRDIINCCCGSISQMHSSIKHAAQMCLISGWKILFASQMEKLLGIYYTLQIAEPSESRYNLIVAMCLDTIDLKQFIHTLIELSTNIAGTVSQDLPNVEDVIETIVRYTFTNIRSQFLVPVVSSFKSSPGSFSSSVLKNKELFDCDPLNAPNIADLNDNDHSIMHKLFSFLSDLMRKIIFLLKESKPGQDSLQPTLKSLIGIYGKVLAQQSIETAEYCWLCISKSNITPKELIHTLNKSGFSRLLLNFIESMRWLLKSYLDSKSVLKSDYKLSKANWKSLNSSSNPMFHFDMLFKFSVNMREIVFAFKPLILLLDKINRLNESLLFVDSEDGSLPGWLYNPCSESLQKIDKVIFRSKDISESTDQLIVIDNRVYDLDRLLMDSREKFDEYLPNRNSKTIITDIVNKSIYRKELLKLLLECYCGEYIDDDSQPISYFDSDNEDYRQLYFIERMLLMLMSDVLLFHQTCCNLMKQSIGFKQLQEFPLALKQIVLKKKTDQSQTNNDTNTATILSFSHMEEKERDEVEETNDMSGTGVINLNEDSNRKMITTCINLLMFGSASSLIGKGTSPIMTNILQWLRSDTYKTKNISKANSMLLLDNIQDSYLNSLFVLNLVALVKHVNLCEELANHIMRQNYEQPISNELTIVIQESFLIRKDIIKRHQQTCISYKELCSNINIRCRFLIDEVEILSINNSAINAGRKKSININDFTSDHLTATPPTTRWKSIAYKAALMLKKPKKSTDYWQIVYNFVMKKFAGKIRQNKSAAIKLVDNSENIREFCGQIYQFLLNKESIDLQKLRTLVLAKKIQFKSLINILKEFKCLLQFSCGLLPGVQVSLLQFFCDKVSIDQSNETGNEAENIYDVLKSANSLSMFNFVSLHTRQSFLQTEYSLVLLSIQILRENLLVNDQKIESIKCMNMLNNQSHIIGIGHWANAKLNLSLCNFLLQTISWSNDIYHLLLANGVLGLIQTLLRQYYESEPGLINIWCQDTPNYQLVMSDSRNIKNETTKCDSIEDLNSSAIALPSQLKKGTLVLRGRDWKYGDQDGPNSVGIVKRECINGMVRVQWLNNKKTASYRAGKDNFYDLRLKKSIEDVKNETPSECGVRSLMKDISMLQEKFRANRLGIKNNETITNSQMKNEIEEVAPSAYLFPSNWNQPSMLLLHSAGQLMQAISIQQLIVNQNNVSKPNGSSDIIFNKIYLLLWLIYKNSILASIHKNDSIKNMYQEQINLWCNPSFLLTLITQHHFPWPNSNGWIDLFLKKAEIEIKISSTENIFNQILTLKILEKLICRSAITDSIIERLWNCLLQAILGHCSEDMKSLFSAHSLNASPSKIKIMELSIIFRNMLRCSSPNRISARNFLFNAISQSLDQQMDNQIQLLGLFCIFSDIENRIYPGIAMSTVKRENEKKQQTYLGIVEEITMIENDKFVVTTVVASAADSCDSFVDWQRDYDIHDLTCDLQIDSSKILFPFEIMSSLTETESEVMSKFLLMLISNFYSSNENILTKTSSLQNVFKIMQLSTLMEFCEHNLTELWYPIYKSNDEVFRSALDMASRACSIKSSISVQELKKALSQLATNIYSGSEEKEPMGSNAKLTDFDYIENSMGIQRKEKKRKSSALSKIMKSKNPHKESRRDPLNINMDLQFQIMEMGFSKRQIQAAVKELARNGNLYLTSNPESIITTILSFQQDDYSLSPVEDNDVEADDDNDEDDDSTGLNLTDDNSSCSTVCDHLQYMMPMHQLHSPTVSDNDDKIYDLYGNDDILTNDDEAFNADSSDDGISEDEEKPMTSDVEKNFNLKGEFNVVCVNNFGEIFVGDQGILSCDGDAIDGYCNVFWTKISKTISTEKLNIHIFTNPTMSIIIGDEVTFSESGIRFHSVPAMTSLSNGIVRQIVRLDSEDDDLKIIVDFPNCIGKVCNISDLKLVVKGQHKYQCQACLKSPISLPMYKCKICRNLYLCSNCHSKFQKSHKHKFLNITADEDAKKPKITNGNLFDDSGKVQTLSVTASVSKSELKQCLSFTNFSLIPQTMSRNIEYTSSNNHCLIKIAEGYRVHKIFMLISLSEFLLLPSHVIVKKGIKSKKLSTVYRAHVQSLKEDEFIINSSKYYSSGLKLMWLKIYQDKRKHQSTERVFSLDLFDESSSLRTVFNAVKSFHIQLMENRVDAKSTAISNDILLKTIFSISDKNWSAEDIDTVCNNTIYNWRQARLNKLRFQMNSNTEDPTTNSDTLSENTVENQDNSKFKSRIMSKIYVWGLNDKDQLGCEATSKVKLPILNEALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLEALDKYFIVKVAVHSGGRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWGDGDFGKLGRGGSSGCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDLDSFLPSQALNRWPHIKEMSYSLSVLDFSPLLFKFNPDPLGAGDVFDIDKNIFQKRNRSDETTQSKNENDENENNDYNLSVVISQLRGRATQVGVICSLFRNLQVLVARNLVSNLMARTCSQSTELTKKESDNLPSTANKRLSVMESFLLAFDYLKLQNALPNQSVLFLQDLLRNTDFNQSNNLRQVGLLLLVDEIEKFGDSNSSKNNGIHHYCDNKDFVTMMKRTRDISIVRESPHPYNENTKLSGKVLIPDAPRLIVEFDRQCSTERNKDVLVIMDHNNSIVAERSGQRWEDWGSKVIINGNELHWSFKSDGSITAWGWRFEVKPLWKQYQDNKIKYDTTENIDNNELLTLFSPNIPLIKELLNEIELQFEDTSLTLQLIKSLSQMAFSRWDLDCESRIWAVRQILAIIRNLNLGVFAQFMKAIDSYSVLSAARSDSKVLTPQDDTPNEPNNFDIEADETSSDEEQVDKSSQLINDIDIICGFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLDSISPVSTADEWAWFRNYCLTYRTTESLITNSSLPYRFINEFKSRFLKEPTVKDPLTREINAITAVSEYADPREFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGKHCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEIIDIAAGGSHSAAISRSGELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTLCITKNEDSRIDLVPNTSVWSWGDGDYGKLGRGGFDICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAWTTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVNRLHASAGTPAGVSILQRAGWAEVENHCDDERRDNGDICVGRTKIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQNGHLPFFISSPDKDCFVLSPYADKTNTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDLLSSLMSLKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIFVNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLIIIWFWEIMEEMTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARIALNPDSLPCAESVPNLPRREINCSQSSSSGSTSPRIYISNSSSSSSSSSQDDDSDASTARAPNALFGSSPSPSDRYSIQRNNQYLVDDYMELINGVFDAPRFMDISLDTEVNEDDDSSEDDHPYGTITSLFRGLRDD 5160

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BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Planmine SMEST
Match: SMESG000006057.1 (SMESG000006057.1)

HSP 1 Score: 218.394 bits (555), Expect = 1.176e-55
Identity = 287/1120 (25.62%), Postives = 469/1120 (41.88%), Query Frame = 2

Query: 11990 GFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLD-SISP--------VSTADEWAW---------FRNYCLTYR--TTESLITNSSLPYRF----INEFKSRFLKEPTVKDPLTREINAITAVS--EYADP--------REFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIG-VACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYF-------RLGHGSDNHVRKPEKVAQL-NRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAW---------TTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVN-RLHASAGTPAGVSILQRAGWAEVENHCDDE-------RRDNGDICVGRT--------KIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQN-GHLPFFISSPDKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIF-----VNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARI 15121
             F+L L K++ +QF  E   VKS   + YS++L+ LI+ +  + L  S+ P         S  ++  W         F+   L +      +L  N  L + F    + +       E  + D +      +  V   EYA            +S +   ++  W +  P+ W       S      + WG   +G+ G         P L   ++    +QI+ G     +++ + ++ A G G          E     I V  L +  +  V+ + G + H +A+   G V++WG     KLG          +  P  +++L     I    G  HSA ++ SG LY +G G  G+LG+        P++V+   G   IG V+CG      L    + D +        V+        K         +    +   +   ++KV CG  FS  LT +GEVYTWG  D+         +    ++H+  P   + L     IID+  G+      T +  +Y WG N    L  G       P ++       + +++CG  H  A          T  SG +    E P+  + L    T  N     +   +  R +L+ +W EL       + L  Q  + +  Q    S  +      + +   GSK      +VN +L+  + +            +EV    + E       R  NG +   RT        +I  ++ VF Q   ++I   D +S              LP R WKVKL+ E  DD GG Y E+I+EIC+EL+N    P  ++    D     P  D T   ++F FLG L+  AIRT +P+ L +  + WK ++   ++ +DL   D    +SL+S+        ++L   Y V       VN   ET    +     V+ +N + +++  I Y++HEFD     IR+    + P+ +L++ S R LE +VCG+ +I I  LK+I  Y     +D+I  WFWEI+       +SLFLRFV G++RLP + S +  + F+   +SK  PA+  LP++ TCF  ++LP Y S++ ++  L  AI  C+SID+DDY  I
Sbjct: 3312 NFILSLHKLLDEQFLEEVELVKSGFSIVYSQYLQCLIQFTTSLNLTGSLMPYYVMEPIDASNRNKSLWMLEIPSETCFQRAILRHNLNINNTLPPNHQLHWLFTIDEVMKLTQAICFERDIPDNIIPRWWWVWCVGSDEYAHHYLQSKWKNNFWSLKQQTELFQWYQDSPEYWI------SEYSNSTYIWGCGIKGEAGFSTNDDWIKPTL---MNINGIQQIVCGSGVTLLITCESKLMACGEGLEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHG----HATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMNHTLAL----STDGQKLYAFGEGVYGKLGVGDVKD--------RFSPTLVDFQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLRLGGKAHAYYPELVFFEKDIHLQQISCGRNHAAASCHAPYSYRNTIPSGPQFQHKEIPE--IPLIKYTTLYN--SEYNFYDMTARLILILYWNEL-------VRLTWQFWIPQTNQHYDKSDYD------LNSISLGSKSLDNASRVNSKLNLFSQSNWNWKPFNNFNISEVRQFINSEFISSAMYRYINGSMINNRTYTSLVRIDRINKKEPVFIQTCRQVIN-MDAVS------------LRLPWRAWKVKLVNEGADDAGGAYDETISEICNELENEAIFPRILTPIPSDTSTFIPNPDPTIPPQYFHFLGILMATAIRTKKPIDLHLDPIFWKRMTKSIVSVDDLLRMDPSYFNSLLSMNEAAALGFDSLDEVYGVDKFVCFSVN-KTETEICHWGLKQKVDVNNVSDFVNRCIYYRLHEFDSAIEHIRKSFCNIAPMVMLDIMSWRHLEKIVCGSKTISIDILKNIARYVDADINDIIFSWFWEILGSFNELEKSLFLRFVTGKSRLPSHDSHIPFRLFI--YISK-QPANS-LPQSQTCFNQIRLPRYKSRSDMEACLRIAISQCRSIDMDDYMLI 4371

HSP 2 Score: 118.242 bits (295), Expect = 2.177e-25
Identity = 112/388 (28.87%), Postives = 169/388 (43.56%), Query Frame = 2

Query: 9428 YVWGLNDKDQLGCEATSK-VKLPILN-EALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLE---------ALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLR-DYKVVQVACGSRDAQTLALTSDFT-VWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYY-------RLGHGTDKHIREPMQIEDLKKTK-IVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
            Y+WG   K + G       +K  ++N   + ++ C     GS     +T   K+   G+                E+I  P   E          L+ Y I  V+   G   H IA+T  GE FSWG G  GKLGH     L  P+ I+  +GK  +   CG  HSA +   G LY +GLG  G+LG+        P LV     + K+  V+CG     TLAL++D   ++++G+G +GKLG G       P  ++      ++++ CG   S ALTENG+V+TWG  D+         +    + H+  P     L     I+ L  G     A+T+   +Y WG N +     G   +   P LV    D  +  ++CG +H+ A
Sbjct: 3493 YIWGCGIKGEAGFSTNDDWIKPTLMNINGIQQIVC-----GSGVTLLITCESKLMACGEG--------------LEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMN--HTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVD-FQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLRLGGKAHAYYPELVFFEKDIHLQQISCGRNHAAA 3858

HSP 3 Score: 75.0998 bits (183), Expect = 2.217e-12
Identity = 72/282 (25.53%), Postives = 122/282 (43.26%), Query Frame = 2

Query: 1412 EKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIY-----------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRH--LPIRITASDLIGVLVKQIAVDGHQSMCLS-NDGAIFTWGS--------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK----YCTEC 2179
            E   +++I+CS  +  VL++ G +   + S        T KH  I   F         + WS     DV   I            S H+LA+T+ GQ+YSWG  + GKLG GD  D+  PT+I+        ++ ++CG  HS  ++++G  +  G  H       + KD +   P+R+  +     ++  I    H +  LS N   ++  GS        T D   +H  +    +     +   +I++I V+ +   VLL +G++Y+        CTEC
Sbjct:  365 ENHSVREIICSENEIIVLNNLGQIRSRSISPPS-----TKKHENIVMLFH--------QCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR--GYNIRNISCGASHSSAVSETGLGFVWGNPHA-----FNSKDENCLFPVRLRQA-----IMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTEC 621

HSP 4 Score: 73.1738 bits (178), Expect = 8.182e-12
Identity = 57/195 (29.23%), Postives = 87/195 (44.62%), Query Frame = 2

Query: 9878 SSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-------TDKHIRE--PMQIEDL------KKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG 10417
            S H  A+   G LY+WG G +G+LGHGD   +  P L+++LR Y +  ++CG+  +  ++ T    VW                 CL P ++    +S+++   CG  S+F L+ N       K + Y LG         T   I +  P  IE L      K  KI  +AV +   L + + G +YS G   HG
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-----NPHAFNSKDENCLFPVRLRQAIMSSIV---CGPHSTFFLSIN-------KRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIG---HG 613

HSP 5 Score: 71.2478 bits (173), Expect = 3.339e-11
Identity = 43/139 (30.94%), Postives = 75/139 (53.96%), Query Frame = 2

Query: 1637 SHVLAVTEAGQ-VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGR-NHMGQL---GHGDVKDR-HLPIRITASDLIGV-LVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRR 2032
            +H LA++  GQ +Y++G    GKLG GD KDR  PT++D   +   ++ +V CG+  S  LT++G++Y+ G  + +G        D+ D  HL +    S L+G+  +  +      +  L+N+  ++ WGS  +N  R
Sbjct: 3690 NHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVDFQKK---KLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLR 3825

HSP 6 Score: 67.0106 bits (162), Expect = 6.146e-10
Identity = 49/180 (27.22%), Postives = 70/180 (38.89%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIY------------------------------------SCGRNH------------------MGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGST 2014
            SH++A+T  G+V+SWG  + GKLG G     K+P  I+   R    +    CG  HS ++T SG +Y                                    SCG NH                   G+LG GDVKDR  P   T  D     + ++      S  L+ +G ++TWG +
Sbjct: 3585 SHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEAL-RGKGSIMS-DCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMNHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSP---TLVDFQKKKLLKVICGKSFSAALTENGEVYTWGHS 3759

HSP 7 Score: 64.6994 bits (156), Expect = 2.773e-9
Identity = 27/69 (39.13%), Postives = 44/69 (63.77%), Query Frame = 2

Query: 9722 GRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWG 9928
             +H +ALT++G+ +SWG G  GKLGH   L  + P  I+  +G  + +++CG+SHS+A+   G  + WG
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG 505

HSP 8 Score: 62.7734 bits (151), Expect = 9.650e-9
Identity = 35/88 (39.77%), Postives = 50/88 (56.82%), Query Frame = 2

Query: 10298 PMQIEDLKKTKIVHLAVG------ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDL 10543
            P+   D+K  KI  LAVG      + H LA+T  GQ+YSWG    G+ G+G +     PTL+ AL    I +++CG+SHS A + + L
Sbjct:  414 PINFPDVK-CKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL 500

HSP 9 Score: 58.9214 bits (141), Expect = 1.580e-7
Identity = 34/99 (34.34%), Postives = 56/99 (56.57%), Query Frame = 2

Query: 10196 AQSSFALTENGQVWTWGKGDYYRLGHG--TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG---QQGNGTVTYNMRPTLVSALM 10477
            +Q   ALT++GQ+++WG G + +LGHG   DKH   P  IE L+   I +++ GA H  AV++ G  + WG N H    +  N      +R  ++S+++
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKH--SPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENCLFPVRLRQAIMSSIV 532

HSP 10 Score: 57.7658 bits (138), Expect = 3.680e-7
Identity = 20/48 (41.67%), Postives = 35/48 (72.92%), Query Frame = 2

Query: 12929 ELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTL 13072
            +LY+WG G +G+LGHG+  D+  P ++EALRGY++  ++CG+  +  +
Sbjct:  448 QLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAV 495

HSP 11 Score: 56.6102 bits (135), Expect = 8.357e-7
Identity = 35/129 (27.13%), Postives = 58/129 (44.96%), Query Frame = 2

Query: 10160 MSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVG---ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            M+++ + QI CG+  +  +T   ++   G+G          +     + +  L   KI H++       H +A+T  G+V+SWG   HG+ G+G  T   +P  + AL         CG  HS   TAS
Sbjct: 3517 MNINGIQQIVCGSGVTLLITCESKLMACGEGLEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTAS 3645

HSP 12 Score: 53.5286 bits (127), Expect = 7.551e-6
Identity = 22/58 (37.93%), Postives = 34/58 (58.62%), Query Frame = 2

Query: 13400 SLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            S H +  T+ G++YSWG    G+LG G       P +IE+L G  I  ++CG++H+ A
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 494

HSP 13 Score: 53.1434 bits (126), Expect = 8.007e-6
Identity = 30/86 (34.88%), Postives = 43/86 (50.00%), Query Frame = 2

Query: 13196 KIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGD 13453
            KIE L     I  D  SQ  L LT  G++Y+WG G + +LGHG       P  +  L    I +++CG+ H    +E G  + WG+
Sbjct:  423 KIEQLAVGWPILND--SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 506

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Planmine SMEST
Match: SMESG000006057.1 (SMESG000006057.1)

HSP 1 Score: 218.009 bits (554), Expect = 1.388e-55
Identity = 287/1120 (25.62%), Postives = 469/1120 (41.88%), Query Frame = 2

Query: 11990 GFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLD-SISP--------VSTADEWAW---------FRNYCLTYR--TTESLITNSSLPYRF----INEFKSRFLKEPTVKDPLTREINAITAVS--EYADP--------REFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIG-VACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYF-------RLGHGSDNHVRKPEKVAQL-NRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAW---------TTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVN-RLHASAGTPAGVSILQRAGWAEVENHCDDE-------RRDNGDICVGRT--------KIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQN-GHLPFFISSPDKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIF-----VNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARI 15121
             F+L L K++ +QF  E   VKS   + YS++L+ LI+ +  + L  S+ P         S  ++  W         F+   L +      +L  N  L + F    + +       E  + D +      +  V   EYA            +S +   ++  W +  P+ W       S      + WG   +G+ G         P L   ++    +QI+ G     +++ + ++ A G G          E     I V  L +  +  V+ + G + H +A+   G V++WG     KLG          +  P  +++L     I    G  HSA ++ SG LY +G G  G+LG+        P++V+   G   IG V+CG      L    + D +        V+        K         +    +   +   ++KV CG  FS  LT +GEVYTWG  D+         +    ++H+  P   + L     IID+  G+      T +  +Y WG N    L  G       P ++       + +++CG  H  A          T  SG +    E P+  + L    T  N     +   +  R +L+ +W EL       + L  Q  + +  Q    S  +      + +   GSK      +VN +L+  + +            +EV    + E       R  NG +   RT        +I  ++ VF Q   ++I   D +S              LP R WKVKL+ E  DD GG Y E+I+EIC+EL+N    P  ++    D     P  D T   ++F FLG L+  AIRT +P+ L +  + WK ++   ++ +DL   D    +SL+S+        ++L   Y V       VN   ET    +     V+ +N + +++  I Y++HEFD     IR+    + P+ +L++ S R LE +VCG+ +I I  LK+I  Y     +D+I  WFWEI+       +SLFLRFV G++RLP + S +  + F+   +SK  PA+  LP++ TCF  ++LP Y S++ ++  L  AI  C+SID+DDY  I
Sbjct: 3288 NFILSLHKLLDEQFLEEVELVKSGFSIVYSQYLQCLIQFTTSLNLTGSLMPYYVMEPIDASNRNKSLWMLEIPSETCFQRAILRHNLNINNTLPPNHQLHWLFTIDEVMKLTQAICFERDIPDNIIPRWWWVWCVGSDEYAHHYLQSKWKNNFWSLKQQTELFQWYQDSPEYWI------SEYSNSTYIWGCGIKGEAGFSTNDDWIKPTL---MNINGIQQIVCGSGVTLLITCESKLMACGEGLEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHG----HATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMNHTLAL----STDGQKLYAFGEGVYGKLGVGDVKD--------RFSPTLVDFQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLRLGGKAHAYYPELVFFEKDIHLQQISCGRNHAAASCHAPYSYRNTIPSGPQFQHKEIPE--IPLIKYTTLYN--SEYNFYDMTARLILILYWNEL-------VRLTWQFWIPQTNQHYDKSDYD------LNSISLGSKSLDNASRVNSKLNLFSQSNWNWKPFNNFNISEVRQFINSEFISSAMYRYINGSMINNRTYTSLVRIDRINKKEPVFIQTCRQVIN-MDAVS------------LRLPWRAWKVKLVNEGADDAGGAYDETISEICNELENEAIFPRILTPIPSDTSTFIPNPDPTIPPQYFHFLGILMATAIRTKKPIDLHLDPIFWKRMTKSIVSVDDLLRMDPSYFNSLLSMNEAAALGFDSLDEVYGVDKFVCFSVN-KTETEICHWGLKQKVDVNNVSDFVNRCIYYRLHEFDSAIEHIRKSFCNIAPMVMLDIMSWRHLEKIVCGSKTISIDILKNIARYVDADINDIIFSWFWEILGSFNELEKSLFLRFVTGKSRLPSHDSHIPFRLFI--YISK-QPANS-LPQSQTCFNQIRLPRYKSRSDMEACLRIAISQCRSIDMDDYMLI 4347

HSP 2 Score: 118.627 bits (296), Expect = 1.664e-25
Identity = 112/388 (28.87%), Postives = 169/388 (43.56%), Query Frame = 2

Query: 9428 YVWGLNDKDQLGCEATSK-VKLPILN-EALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLE---------ALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLR-DYKVVQVACGSRDAQTLALTSDFT-VWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYY-------RLGHGTDKHIREPMQIEDLKKTK-IVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
            Y+WG   K + G       +K  ++N   + ++ C     GS     +T   K+   G+                E+I  P   E          L+ Y I  V+   G   H IA+T  GE FSWG G  GKLGH     L  P+ I+  +GK  +   CG  HSA +   G LY +GLG  G+LG+        P LV     + K+  V+CG     TLAL++D   ++++G+G +GKLG G       P  ++      ++++ CG   S ALTENG+V+TWG  D+         +    + H+  P     L     I+ L  G     A+T+   +Y WG N +     G   +   P LV    D  +  ++CG +H+ A
Sbjct: 3469 YIWGCGIKGEAGFSTNDDWIKPTLMNINGIQQIVC-----GSGVTLLITCESKLMACGEG--------------LEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMN--HTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVD-FQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLRLGGKAHAYYPELVFFEKDIHLQQISCGRNHAAA 3834

HSP 3 Score: 75.0998 bits (183), Expect = 2.253e-12
Identity = 72/282 (25.53%), Postives = 122/282 (43.26%), Query Frame = 2

Query: 1412 EKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIY-----------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRH--LPIRITASDLIGVLVKQIAVDGHQSMCLS-NDGAIFTWGS--------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK----YCTEC 2179
            E   +++I+CS  +  VL++ G +   + S        T KH  I   F         + WS     DV   I            S H+LA+T+ GQ+YSWG  + GKLG GD  D+  PT+I+        ++ ++CG  HS  ++++G  +  G  H       + KD +   P+R+  +     ++  I    H +  LS N   ++  GS        T D   +H  +    +     +   +I++I V+ +   VLL +G++Y+        CTEC
Sbjct:  365 ENHSVREIICSENEIIVLNNLGQIRSRSISPPS-----TKKHENIVMLFH--------QCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR--GYNIRNISCGASHSSAVSETGLGFVWGNPHA-----FNSKDENCLFPVRLRQA-----IMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTEC 621

HSP 4 Score: 73.1738 bits (178), Expect = 7.274e-12
Identity = 57/195 (29.23%), Postives = 87/195 (44.62%), Query Frame = 2

Query: 9878 SSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-------TDKHIRE--PMQIEDL------KKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG 10417
            S H  A+   G LY+WG G +G+LGHGD   +  P L+++LR Y +  ++CG+  +  ++ T    VW                 CL P ++    +S+++   CG  S+F L+ N       K + Y LG         T   I +  P  IE L      K  KI  +AV +   L + + G +YS G   HG
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-----NPHAFNSKDENCLFPVRLRQAIMSSIV---CGPHSTFFLSIN-------KRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIG---HG 613

HSP 5 Score: 71.2478 bits (173), Expect = 3.337e-11
Identity = 43/139 (30.94%), Postives = 75/139 (53.96%), Query Frame = 2

Query: 1637 SHVLAVTEAGQ-VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGR-NHMGQL---GHGDVKDR-HLPIRITASDLIGV-LVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRR 2032
            +H LA++  GQ +Y++G    GKLG GD KDR  PT++D   +   ++ +V CG+  S  LT++G++Y+ G  + +G        D+ D  HL +    S L+G+  +  +      +  L+N+  ++ WGS  +N  R
Sbjct: 3666 NHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVDFQKK---KLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLR 3801

HSP 6 Score: 67.0106 bits (162), Expect = 5.557e-10
Identity = 49/180 (27.22%), Postives = 70/180 (38.89%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIY------------------------------------SCGRNH------------------MGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGST 2014
            SH++A+T  G+V+SWG  + GKLG G     K+P  I+   R    +    CG  HS ++T SG +Y                                    SCG NH                   G+LG GDVKDR  P   T  D     + ++      S  L+ +G ++TWG +
Sbjct: 3561 SHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEAL-RGKGSIMS-DCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMNHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSP---TLVDFQKKKLLKVICGKSFSAALTENGEVYTWGHS 3735

HSP 7 Score: 64.6994 bits (156), Expect = 2.528e-9
Identity = 53/234 (22.65%), Postives = 99/234 (42.31%), Query Frame = 2

Query: 9722 GRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIE------CMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQ-IEDLKKTKIVHLAVGALHCLAVTDRGQVYSWG 10402
             +H +ALT++G+ +SWG G  GKLGH   L  + P  I+  +G  + +++CG+SHS+A+   G  + WG        H   +   +      LR   +  + CG      L++      +        +L          P  IE      C     + +I   +     L  NG +++ G G    LG  T+  I +  + ++ + + K+  +++   H + +  +  +YSW 
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG------NPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHG--INLG-CTECQIHKTFEKVQCMSRHKVFDISLSENH-IVILGQNVIYSWS 660

HSP 8 Score: 63.1586 bits (152), Expect = 9.408e-9
Identity = 35/88 (39.77%), Postives = 50/88 (56.82%), Query Frame = 2

Query: 10298 PMQIEDLKKTKIVHLAVG------ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDL 10543
            P+   D+K  KI  LAVG      + H LA+T  GQ+YSWG    G+ G+G +     PTL+ AL    I +++CG+SHS A + + L
Sbjct:  414 PINFPDVK-CKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL 500

HSP 9 Score: 58.9214 bits (141), Expect = 1.429e-7
Identity = 34/99 (34.34%), Postives = 56/99 (56.57%), Query Frame = 2

Query: 10196 AQSSFALTENGQVWTWGKGDYYRLGHG--TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG---QQGNGTVTYNMRPTLVSALM 10477
            +Q   ALT++GQ+++WG G + +LGHG   DKH   P  IE L+   I +++ GA H  AV++ G  + WG N H    +  N      +R  ++S+++
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKH--SPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENCLFPVRLRQAIMSSIV 532

HSP 10 Score: 57.7658 bits (138), Expect = 3.528e-7
Identity = 20/48 (41.67%), Postives = 35/48 (72.92%), Query Frame = 2

Query: 12929 ELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTL 13072
            +LY+WG G +G+LGHG+  D+  P ++EALRGY++  ++CG+  +  +
Sbjct:  448 QLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAV 495

HSP 11 Score: 56.6102 bits (135), Expect = 8.012e-7
Identity = 35/129 (27.13%), Postives = 58/129 (44.96%), Query Frame = 2

Query: 10160 MSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVG---ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            M+++ + QI CG+  +  +T   ++   G+G          +     + +  L   KI H++       H +A+T  G+V+SWG   HG+ G+G  T   +P  + AL         CG  HS   TAS
Sbjct: 3493 MNINGIQQIVCGSGVTLLITCESKLMACGEGLEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTAS 3621

HSP 12 Score: 53.5286 bits (127), Expect = 7.120e-6
Identity = 22/58 (37.93%), Postives = 34/58 (58.62%), Query Frame = 2

Query: 13400 SLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            S H +  T+ G++YSWG    G+LG G       P +IE+L G  I  ++CG++H+ A
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 494

HSP 13 Score: 53.1434 bits (126), Expect = 7.872e-6
Identity = 30/86 (34.88%), Postives = 43/86 (50.00%), Query Frame = 2

Query: 13196 KIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGD 13453
            KIE L     I  D  SQ  L LT  G++Y+WG G + +LGHG       P  +  L    I +++CG+ H    +E G  + WG+
Sbjct:  423 KIEQLAVGWPILND--SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 506

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Planmine SMEST
Match: SMESG000006057.1 (SMESG000006057.1)

HSP 1 Score: 218.009 bits (554), Expect = 1.475e-55
Identity = 287/1120 (25.62%), Postives = 469/1120 (41.88%), Query Frame = 2

Query: 11990 GFLLCLQKVVLKQFKFEEPEVKSSKQLFYSRFLKSLIELSCYIRLD-SISP--------VSTADEWAW---------FRNYCLTYR--TTESLITNSSLPYRF----INEFKSRFLKEPTVKDPLTREINAITAV--SEYADP--------REFSYQHDLQIVGWLKSRPDAWKKCWPIDSASGLEVWSWGHNHRGQLGGVEGSKIKVPVLCEHLSALRPRQIIGGEQSLFIVSIDGRVYATGFGNNGRLGIGSTESVQTPILVSGLEEKIVVKVAVNSGGK-HCLALCNNGLVYAWGDAEDNKLGLDIRVQPGEDVLTPTLVKSLVKAEXXXXXXXXXXXXXXXXXXELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIG-VACGSGDAQTLCITKNEDSRIDLVPNTSVWSWXXXXXXXXXXXXXXICKLPMKIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYF-------RLGHGSDNHVRKPEKVAQL-NRKKIIDVACGSLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLAW---------TTVSGNKSHETESPDQRLSLSTRPTSCNLLENKSAVSLINRFLLLHHWTELFCSNLHFMDLNRQSVMDKVRQILLPSSKESLFRLMVQTTMYGSKKHGPEIKVN-RLHASAGTPAGVSILQRAGWAEVENHCDDE-------RRDNGDICVGRT--------KIQLEKTVFGQLGGKLIEEADCISKSGSIFVPPPDFFLLPNRVWKVKLIGESVDDCGGGYSESITEICDELQN-GHLPFFISSPDKDCFVLSPYADKT-NTKWFIFLGCLLGIAIRTNQPLSLTVSDLIWKILSGQSLNKNDLQLFDKDXXXXXXXXKAIDETELENLQIPYSVTAIDGKEVNLNIETSGAIF-----VNASNRNSYIDEVINYKIHEFDKTCLFIRRGISLVIPLPLLNLFSSRELECLVCGNDSIPISFLKSITLYRGVKSDDLXXXXXXXXXXXXTNEVRSLFLRFVWGRTRLPRYVSDLRGKEFVIQVLSKYSPADDYLPEAYTCFFLLKLPNYSSKAILQEKLLYAIHFCKSIDIDDYARI 15121
             F+L L K++ +QF  E   VKS   + YS++L+ LI+ +  + L  S+ P         S  ++  W         F+   L +      +L  N  L + F    + +       E  + D +      +  V   EYA            +S +   ++  W +  P+ W       S      + WG   +G+ G         P L   ++    +QI+ G     +++ + ++ A G G          E     I V  L +  +  V+ + G + H +A+   G V++WG     KLG          +  P  +++L     I    G  HSA ++ SG LY +G G  G+LG+        P++V+   G   IG V+CG      L    + D +        V+        K         +    +   +   ++KV CG  FS  LT +GEVYTWG  D+         +    ++H+  P   + L     IID+  G+      T +  +Y WG N    L  G       P ++       + +++CG  H  A          T  SG +    E P+  + L    T  N     +   +  R +L+ +W EL       + L  Q  + +  Q    S  +      + +   GSK      +VN +L+  + +            +EV    + E       R  NG +   RT        +I  ++ VF Q   ++I   D +S              LP R WKVKL+ E  DD GG Y E+I+EIC+EL+N    P  ++    D     P  D T   ++F FLG L+  AIRT +P+ L +  + WK ++   ++ +DL   D    +SL+S+        ++L   Y V       VN   ET    +     V+ +N + +++  I Y++HEFD     IR+    + P+ +L++ S R LE +VCG+ +I I  LK+I  Y     +D+I  WFWEI+       +SLFLRFV G++RLP + S +  + F+   +SK  PA+  LP++ TCF  ++LP Y S++ ++  L  AI  C+SID+DDY  I
Sbjct: 3095 NFILSLHKLLDEQFLEEVELVKSGFSIVYSQYLQCLIQFTTSLNLTGSLMPYYVMEPIDASNRNKSLWMLEIPSETCFQRAILRHNLNINNTLPPNHQLHWLFTIDEVMKLTQAICFERDIPDNIIPRWWWVWCVGSDEYAHHYLQSKWKNNFWSLKQQTELFQWYQDSPEYWI------SEYSNSTYIWGCGIKGEAGFSTNDDWIKPTL---MNINGIQQIVCGSGVTLLITCESKLMACGEGLEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHG----HATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMNHTLAL----STDGQKLYAFGEGVYGKLGVGDVKD--------RFSPTLVDFQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLRLGGKAHAYYPELVFFEKDIHLQQISCGRNHAAASCHAPYSYRNTIPSGPQFQHKEIPE--IPLIKYTTLYN--SEYNFYDMTARLILILYWNEL-------VRLTWQFWIPQTNQHYDKSDYD------LNSISLGSKSLDNASRVNSKLNLFSQSNWNWKPFNNFNISEVRQFINSEFISSAMYRYINGSMINNRTYTSLVRIDRINKKEPVFIQTCRQVIN-MDAVS------------LRLPWRAWKVKLVNEGADDAGGAYDETISEICNELENEAIFPRILTPIPSDTSTFIPNPDPTIPPQYFHFLGILMATAIRTKKPIDLHLDPIFWKRMTKSIVSVDDLLRMDPSYFNSLLSMNEAAALGFDSLDEVYGVDKFVCFSVN-KTETEICHWGLKQKVDVNNVSDFVNRCIYYRLHEFDSAIEHIRKSFCNIAPMVMLDIMSWRHLEKIVCGSKTISIDILKNIARYVDADINDIIFSWFWEILGSFNELEKSLFLRFVTGKSRLPSHDSHIPFRLFI--YISK-QPANS-LPQSQTCFNQIRLPRYKSRSDMEACLRIAISQCRSIDMDDYMLI 4154

HSP 2 Score: 118.242 bits (295), Expect = 1.971e-25
Identity = 112/388 (28.87%), Postives = 169/388 (43.56%), Query Frame = 2

Query: 9428 YVWGLNDKDQLGCEATSK-VKLPILN-EALSELDCVSISGGSKSLFCVTRTGKVYVAGDSSNGRLGIGSDTDITAEVIIGPKRLE---------ALDKYFIVKVAVHSGGR-HAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLR-DYKVVQVACGSRDAQTLALTSDFT-VWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYY-------RLGHGTDKHIREPMQIEDLKKTK-IVHLAVGALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVA 10525
            Y+WG   K + G       +K  ++N   + ++ C     GS     +T   K+   G+                E+I  P   E          L+ Y I  V+   G   H IA+T  GE FSWG G  GKLGH     L  P+ I+  +GK  +   CG  HSA +   G LY +GLG  G+LG+        P LV     + K+  V+CG     TLAL++D   ++++G+G +GKLG G       P  ++      ++++ CG   S ALTENG+V+TWG  D+         +    + H+  P     L     I+ L  G     A+T+   +Y WG N +     G   +   P LV    D  +  ++CG +H+ A
Sbjct: 3276 YIWGCGIKGEAGFSTNDDWIKPTLMNINGIQQIVC-----GSGVTLLITCESKLMACGEG--------------LEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMN--HTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVD-FQKKKLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLRLGGKAHAYYPELVFFEKDIHLQQISCGRNHAAA 3641

HSP 3 Score: 75.0998 bits (183), Expect = 1.899e-12
Identity = 72/282 (25.53%), Postives = 122/282 (43.26%), Query Frame = 2

Query: 1412 EKFRIKKIVCSGVDTYVLSDCGWLYEVNTSSDDVIDTFTFKHNAINHQFDCLKNDSVLKLWSKNRVIDVDANIY-----------SSHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGRNHMGQLGHGDVKDRH--LPIRITASDLIGVLVKQIAVDGHQSMCLS-NDGAIFTWGS--------TFDNCRRHLSNWSPKIETCVNEYRNEIDQIQVHDSTYSVLLKSGSVYTWLK----YCTEC 2179
            E   +++I+CS  +  VL++ G +   + S        T KH  I   F         + WS     DV   I            S H+LA+T+ GQ+YSWG  + GKLG GD  D+  PT+I+        ++ ++CG  HS  ++++G  +  G  H       + KD +   P+R+  +     ++  I    H +  LS N   ++  GS        T D   +H  +    +     +   +I++I V+ +   VLL +G++Y+        CTEC
Sbjct:  365 ENHSVREIICSENEIIVLNNLGQIRSRSISPPS-----TKKHENIVMLFH--------QCWSPINFPDVKCKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALR--GYNIRNISCGASHSSAVSETGLGFVWGNPHA-----FNSKDENCLFPVRLRQA-----IMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHGINLGCTEC 621

HSP 4 Score: 73.1738 bits (178), Expect = 7.558e-12
Identity = 57/195 (29.23%), Postives = 87/195 (44.62%), Query Frame = 2

Query: 9878 SSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIECMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHG-------TDKHIRE--PMQIEDL------KKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG 10417
            S H  A+   G LY+WG G +G+LGHGD   +  P L+++LR Y +  ++CG+  +  ++ T    VW                 CL P ++    +S+++   CG  S+F L+ N       K + Y LG         T   I +  P  IE L      K  KI  +AV +   L + + G +YS G   HG
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-----NPHAFNSKDENCLFPVRLRQAIMSSIV---CGPHSTFFLSIN-------KRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIG---HG 613

HSP 5 Score: 71.2478 bits (173), Expect = 2.983e-11
Identity = 43/139 (30.94%), Postives = 75/139 (53.96%), Query Frame = 2

Query: 1637 SHVLAVTEAGQ-VYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIYSCGR-NHMGQL---GHGDVKDR-HLPIRITASDLIGV-LVKQIAVDGHQSMCLSNDGAIFTWGSTFDNCRR 2032
            +H LA++  GQ +Y++G    GKLG GD KDR  PT++D   +   ++ +V CG+  S  LT++G++Y+ G  + +G        D+ D  HL +    S L+G+  +  +      +  L+N+  ++ WGS  +N  R
Sbjct: 3473 NHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSPTLVDFQKK---KLLKVICGKSFSAALTENGEVYTWGHSDFVGTFLSDSEVDLTDESHLLVPTLNSSLVGIGFIIDLCAGNDTTFALTNNCHLYGWGSNANNLLR 3608

HSP 6 Score: 67.0106 bits (162), Expect = 5.539e-10
Identity = 49/180 (27.22%), Postives = 70/180 (38.89%), Query Frame = 2

Query: 1637 SHVLAVTEAGQVYSWGTNTSGKLGQGDTKDRKRPTIIDTFSRCHLQVKQVACGEEHSLILTQSGDIY------------------------------------SCGRNH------------------MGQLGHGDVKDRHLPIRITASDLIGVLVKQIAVDGHQSMCLSNDGAIFTWGST 2014
            SH++A+T  G+V+SWG  + GKLG G     K+P  I+   R    +    CG  HS ++T SG +Y                                    SCG NH                   G+LG GDVKDR  P   T  D     + ++      S  L+ +G ++TWG +
Sbjct: 3368 SHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEAL-RGKGSIMS-DCGHMHSAVVTASGGLYMFGLGVNGQLGNEILCGCDTPRLVDFTDGEPKIGFVSCGMNHTLALSTDGQKLYAFGEGVYGKLGVGDVKDRFSP---TLVDFQKKKLLKVICGKSFSAALTENGEVYTWGHS 3542

HSP 7 Score: 65.0846 bits (157), Expect = 2.478e-9
Identity = 53/234 (22.65%), Postives = 99/234 (42.31%), Query Frame = 2

Query: 9722 GRHAIALTKNGETFSWGEGDDGKLGHNSRLKLNYPRKIKYFKGKRVVDVACGSSHSAAIVFGGHLYTWGLGDYGRLGHGDTAMRLHPELVKSLRDYKVVQVACGSRDAQTLALTSDFTVWSWXXXXXXXXXXXXXXXCLIPQKIE------CMSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQ-IEDLKKTKIVHLAVGALHCLAVTDRGQVYSWG 10402
             +H +ALT++G+ +SWG G  GKLGH   L  + P  I+  +G  + +++CG+SHS+A+   G  + WG        H   +   +      LR   +  + CG      L++      +        +L          P  IE      C     + +I   +     L  NG +++ G G    LG  T+  I +  + ++ + + K+  +++   H + +  +  +YSW 
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG------NPHAFNSKDENCLFPVRLRQAIMSSIVCGPHSTFFLSINKRNVYYLGSQCSENELFTKDFILQHYPSIIEGLPFTKCDKSEKIEKIAVNSTVVLVLLNNGNLYSIGHG--INLG-CTECQIHKTFEKVQCMSRHKVFDISLSENH-IVILGQNVIYSWS 660

HSP 8 Score: 62.7734 bits (151), Expect = 1.037e-8
Identity = 35/88 (39.77%), Postives = 50/88 (56.82%), Query Frame = 2

Query: 10298 PMQIEDLKKTKIVHLAVG------ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTASDL 10543
            P+   D+K  KI  LAVG      + H LA+T  GQ+YSWG    G+ G+G +     PTL+ AL    I +++CG+SHS A + + L
Sbjct:  414 PINFPDVK-CKIEQLAVGWPILNDSQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGL 500

HSP 9 Score: 58.9214 bits (141), Expect = 1.523e-7
Identity = 34/99 (34.34%), Postives = 56/99 (56.57%), Query Frame = 2

Query: 10196 AQSSFALTENGQVWTWGKGDYYRLGHG--TDKHIREPMQIEDLKKTKIVHLAVGALHCLAVTDRGQVYSWGDNDHG---QQGNGTVTYNMRPTLVSALM 10477
            +Q   ALT++GQ+++WG G + +LGHG   DKH   P  IE L+   I +++ GA H  AV++ G  + WG N H    +  N      +R  ++S+++
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKH--SPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWG-NPHAFNSKDENCLFPVRLRQAIMSSIV 532

HSP 10 Score: 57.7658 bits (138), Expect = 3.374e-7
Identity = 20/48 (41.67%), Postives = 35/48 (72.92%), Query Frame = 2

Query: 12929 ELYTWGKGRYGRLGHGNGDDQPFPKIVEALRGYHVIGVACGSGDAQTL 13072
            +LY+WG G +G+LGHG+  D+  P ++EALRGY++  ++CG+  +  +
Sbjct:  448 QLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAV 495

HSP 11 Score: 56.6102 bits (135), Expect = 8.616e-7
Identity = 35/129 (27.13%), Postives = 58/129 (44.96%), Query Frame = 2

Query: 10160 MSLSNVIQIECGAQSSFALTENGQVWTWGKGDYYRLGHGTDKHIREPMQIEDLKKTKIVHLAVG---ALHCLAVTDRGQVYSWGDNDHGQQGNGTVTYNMRPTLVSALMDNKIAHVACGSSHSVAWTAS 10537
            M+++ + QI CG+  +  +T   ++   G+G          +     + +  L   KI H++       H +A+T  G+V+SWG   HG+ G+G  T   +P  + AL         CG  HS   TAS
Sbjct: 3300 MNINGIQQIVCGSGVTLLITCESKLMACGEGLEMIFNPFMREETYRIINVPVLNDYKITHVSASKGPESHIIAITIFGEVFSWGIGSHGKLGHGHATTLKKPKSIEALRGKGSIMSDCGHMHSAVVTAS 3428

HSP 12 Score: 53.5286 bits (127), Expect = 7.406e-6
Identity = 22/58 (37.93%), Postives = 34/58 (58.62%), Query Frame = 2

Query: 13400 SLHCICCTEDGEVYSWGDNDEGQLGDGTTTTNSRPRIIESLTGKGINRVACGSAHTLA 13573
            S H +  T+ G++YSWG    G+LG G       P +IE+L G  I  ++CG++H+ A
Sbjct:  437 SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSA 494

HSP 13 Score: 53.1434 bits (126), Expect = 8.189e-6
Identity = 30/86 (34.88%), Postives = 43/86 (50.00%), Query Frame = 2

Query: 13196 KIETLEGAGVIKVDCGSQFSLVLTASGEVYTWGKGDYFRLGHGSDNHVRKPEKVAQLNRKKIIDVACGSLHCICCTEDGEVYSWGD 13453
            KIE L     I  D  SQ  L LT  G++Y+WG G + +LGHG       P  +  L    I +++CG+ H    +E G  + WG+
Sbjct:  423 KIEQLAVGWPILND--SQHILALTQHGQLYSWGGGSFGKLGHGDMLDKHSPTLIEALRGYNIRNISCGASHSSAVSETGLGFVWGN 506

[Close]

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Planmine SMEST
Match: SMESG000018659.1 (SMESG000018659.1)

HSP 1 Score: 190.66 bits (483), Expect = 1.613e-52
Identity = 100/137 (72.99%), Postives = 111/137 (81.02%), Query Frame = 2

Query: 7043 YDIHDLTCDLQIDSSKILFPFEIMSSLTETESEVMSKFLLMLISNFYSSNENILTKTSSLQNVFKIMQLSTLMEFCEHNLTELWYPIYKSNDEVFRSALDMASRACSIKSSISVQELKKALSQLATNIYSGSEEKEP 7453
            Y    L C + + SSKILFPFEIMSSLTETESE+MSKFLLMLI NFYSSN N+LTKTSS+QNVFKIMQLSTLMEFC+HNLTELWYPI++SNDEVF S LDM SRACSIKSSISVQE      +++T   SG   K P
Sbjct:  116 YAYCGLFCAV-LSSSKILFPFEIMSSLTETESEIMSKFLLMLIFNFYSSNNNVLTKTSSVQNVFKIMQLSTLMEFCKHNLTELWYPIFQSNDEVFMSELDMDSRACSIKSSISVQE--STSFKMSTKSKSGKTNKSP 249

The following BLAST results are available for this feature:

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Celegans
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Fly
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Zebrafish
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Xenopus
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Mouse
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. UniProt/SwissProt
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. TrEMBL
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Cavefish
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Sea Lamprey
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Yeast
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Nematostella
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Medaka
BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Planmine SMEST

BLAST of HECT and RLD domain containing E3 ubiquitin protein ligase 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5

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HECT and RLD domain containing E3 ubiquitin protein ligase 2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13