Ubiquitin-conjugating enzyme E2 variant 2

Overview
NameUbiquitin-conjugating enzyme E2 variant 2
Smed IDSMED30011574
Length (bp)830
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ubiquitin-conjugating enzyme E2 variant 2 (SMED30011574) t-SNE clustered cells

Violin plots show distribution of expression levels for Ubiquitin-conjugating enzyme E2 variant 2 (SMED30011574) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ubiquitin-conjugating enzyme E2 variant 2 (SMED30011574) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ubiquitin-conjugating enzyme E2 variant 2 (SMED30011574) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011574

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30011574h1SMcG0018450 dd_Smed_v4_1036_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30011574h1SMcG0018450 dd_Smed_v4_1036_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Human
Match: UBE2V1 (ubiquitin conjugating enzyme E2 V1 [Source:HGNC Symbol;Acc:HGNC:12494])

HSP 1 Score: 158.303 bits (399), Expect = 4.486e-48
Identity = 72/135 (53.33%), Postives = 98/135 (72.59%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP VRF +KI M GVN +NG++D +  S L+ W    +IK+VL ++R+ M+ KEN KL QP E   +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Human
Match: UBE2V1 (ubiquitin conjugating enzyme E2 V1 [Source:HGNC Symbol;Acc:HGNC:12494])

HSP 1 Score: 158.303 bits (399), Expect = 8.945e-48
Identity = 72/135 (53.33%), Postives = 98/135 (72.59%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP VRF +KI M GVN +NG++D +  S L+ W    +IK+VL ++R+ M+ KEN KL QP E   +
Sbjct:   34 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 168
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Human
Match: UBE2V1 (ubiquitin conjugating enzyme E2 V1 [Source:HGNC Symbol;Acc:HGNC:12494])

HSP 1 Score: 158.303 bits (399), Expect = 8.945e-48
Identity = 72/135 (53.33%), Postives = 98/135 (72.59%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP VRF +KI M GVN +NG++D +  S L+ W    +IK+VL ++R+ M+ KEN KL QP E   +
Sbjct:   34 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 168
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Human
Match: UBE2V2 (ubiquitin conjugating enzyme E2 V2 [Source:HGNC Symbol;Acc:HGNC:12495])

HSP 1 Score: 157.147 bits (396), Expect = 1.192e-47
Identity = 69/135 (51.11%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP+VRF +KI M G+N ++G++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E  T+
Sbjct:    9 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Human
Match: TMEM189-UBE2V1 (TMEM189-UBE2V1 readthrough [Source:HGNC Symbol;Acc:HGNC:33521])

HSP 1 Score: 160.229 bits (404), Expect = 3.082e-46
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 2 
Query:   56 YIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +  T    +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP VRF +KI M GVN +NG++D +  S L+ W    +IK+VL ++R+ M+ KEN KL QP E   +
Sbjct:  226 FCITTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 368
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Celegans
Match: uev-1 (Ubiquitin-conjugating enzyme E2 variant 1 [Source:UniProtKB/Swiss-Prot;Acc:O45495])

HSP 1 Score: 167.162 bits (422), Expect = 3.889e-52
Identity = 79/136 (58.09%), Postives = 101/136 (74.26%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKG-MLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KGK DG ISWGL DD D T+T W   I+GP ++PY+ +IY+L+I C   YP EPPTVRFT+K+ MVGVN++NG+IDK+  +TL +W+    IK VL DIRK  M+ KEN KL QPAE + F
Sbjct:    4 VPRNFRLLEELEEGQKGKGDGNISWGLEDDSDMTLTRWTASIIGPPRTPYESRIYNLQIQCGGNYPREPPTVRFTTKVHMVGVNQSNGVIDKRNLTTLRNWSNSYMIKTVLEDIRKNMMMAKENLKLQQPAEGAMF 139
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Celegans
Match: uev-1 (Ubiquitin-conjugating enzyme E2 variant 1 [Source:UniProtKB/Swiss-Prot;Acc:O45495])

HSP 1 Score: 167.162 bits (422), Expect = 3.889e-52
Identity = 79/136 (58.09%), Postives = 101/136 (74.26%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKG-MLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KGK DG ISWGL DD D T+T W   I+GP ++PY+ +IY+L+I C   YP EPPTVRFT+K+ MVGVN++NG+IDK+  +TL +W+    IK VL DIRK  M+ KEN KL QPAE + F
Sbjct:    4 VPRNFRLLEELEEGQKGKGDGNISWGLEDDSDMTLTRWTASIIGPPRTPYESRIYNLQIQCGGNYPREPPTVRFTTKVHMVGVNQSNGVIDKRNLTTLRNWSNSYMIKTVLEDIRKNMMMAKENLKLQQPAEGAMF 139
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Celegans
Match: let-70 (Ubiquitin-conjugating enzyme E2 2 [Source:UniProtKB/Swiss-Prot;Acc:P35129])

HSP 1 Score: 55.8398 bits (133), Expect = 1.168e-9
Identity = 35/105 (33.33%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  +      S G V DD   + +W   I+GP +SPY G ++ L I     YP +PP V FT++I    +N    + +D  R    S W+   TI  VL  I
Sbjct:    9 ELQDLGRDPPAQCSAGPVGDD---LFHWQATIMGPPESPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Celegans
Match: ubc-1 (Ubiquitin-conjugating enzyme E2 1 [Source:UniProtKB/Swiss-Prot;Acc:P52478])

HSP 1 Score: 48.9062 bits (115), Expect = 8.235e-7
Identity = 17/41 (41.46%), Postives = 30/41 (73.17%), Query Frame = 2 
Query:  188 WNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKI 310
            W  +I GP ++P++   + L ++ TE+YP++PPTV+F SK+
Sbjct:   36 WEAIIFGPQETPFEDGTFKLSLEFTEEYPNKPPTVKFISKM 76
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Celegans
Match: ubc-21 (Probable ubiquitin-conjugating enzyme E2 21 [Source:UniProtKB/Swiss-Prot;Acc:P52484])

HSP 1 Score: 48.9062 bits (115), Expect = 8.513e-7
Identity = 26/85 (30.59%), Postives = 40/85 (47.06%), Query Frame = 2 
Query:  194 GMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENS 448
            G I GP  +PY G  + +K+D  E YP EPP  +F ++I    ++   G I          WT   T++ VL  ++  +   E S
Sbjct:   55 GFIKGPEGTPYAGGTFEIKVDIPEHYPFEPPKAKFVTRIWHPNISSQTGTICLDILK--DKWTASLTLRTVLLSLQAMLCSPEPS 137
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Fly
Match: Uev1A (gene:FBgn0035601 transcript:FBtr0345026)

HSP 1 Score: 163.696 bits (413), Expect = 1.646e-50
Identity = 72/137 (52.55%), Postives = 102/137 (74.45%), Query Frame = 2 
Query:   74 AVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
             V+PR+F LL+EL++G KG  DGTISWGL +DDD T+TYW GMI+GP ++P++ ++YSLKI+C E+YPDEPPT+RF +K+ +  +N+ NG++D +    L+ W+R   IK +L +IR+ M  KEN KL QP E S F
Sbjct:    9 VVVPRNFRLLEELDQGQKGVGDGTISWGLENDDDMTLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFITKVNINCINQNNGVVDHRSVQMLARWSREYNIKTMLQEIRRIMTMKENLKLAQPPEGSCF 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Fly
Match: Uev1A (gene:FBgn0035601 transcript:FBtr0077155)

HSP 1 Score: 163.696 bits (413), Expect = 1.646e-50
Identity = 72/137 (52.55%), Postives = 102/137 (74.45%), Query Frame = 2 
Query:   74 AVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
             V+PR+F LL+EL++G KG  DGTISWGL +DDD T+TYW GMI+GP ++P++ ++YSLKI+C E+YPDEPPT+RF +K+ +  +N+ NG++D +    L+ W+R   IK +L +IR+ M  KEN KL QP E S F
Sbjct:    9 VVVPRNFRLLEELDQGQKGVGDGTISWGLENDDDMTLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFITKVNINCINQNNGVVDHRSVQMLARWSREYNIKTMLQEIRRIMTMKENLKLAQPPEGSCF 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Fly
Match: Uev1A (gene:FBgn0035601 transcript:FBtr0077156)

HSP 1 Score: 122.094 bits (305), Expect = 5.703e-35
Identity = 50/102 (49.02%), Postives = 74/102 (72.55%), Query Frame = 2 
Query:  176 TMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            T+TYW GMI+GP ++P++ ++YSLKI+C E+YPDEPPT+RF +K+ +  +N+ NG++D +    L+ W+R   IK +L +IR+ M  KEN KL QP E S F
Sbjct:    2 TLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFITKVNINCINQNNGVVDHRSVQMLARWSREYNIKTMLQEIRRIMTMKENLKLAQPPEGSCF 103
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Fly
Match: eff (gene:FBgn0011217 transcript:FBtr0310554)

HSP 1 Score: 55.0694 bits (131), Expect = 3.423e-9
Identity = 35/105 (33.33%), Postives = 50/105 (47.62%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  +      S G V DD   + +W   I+GP  SPY G ++ L I     YP +PP V FT++I    +N    + +D  R    S W+   TI  VL  I
Sbjct:    9 ELQDLGRDPPAQCSAGPVGDD---LFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Fly
Match: eff (gene:FBgn0011217 transcript:FBtr0336876)

HSP 1 Score: 55.0694 bits (131), Expect = 3.423e-9
Identity = 35/105 (33.33%), Postives = 50/105 (47.62%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  +      S G V DD   + +W   I+GP  SPY G ++ L I     YP +PP V FT++I    +N    + +D  R    S W+   TI  VL  I
Sbjct:    9 ELQDLGRDPPAQCSAGPVGDD---LFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Zebrafish
Match: ube2v2 (ubiquitin-conjugating enzyme E2 variant 2 [Source:NCBI gene;Acc:406836])

HSP 1 Score: 160.229 bits (404), Expect = 3.735e-49
Identity = 71/135 (52.59%), Postives = 100/135 (74.07%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP+++ Y+ +IYSLK++C  KYP+ PPTVRF +KI M G+N +NG++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E  T+
Sbjct:    9 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPARTNYENRIYSLKVECGPKYPEVPPTVRFVTKISMNGINNSNGMVDARSIPILAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Zebrafish
Match: ube2v1 (ubiquitin-conjugating enzyme E2 variant 1 [Source:ZFIN;Acc:ZDB-GENE-051030-102])

HSP 1 Score: 150.599 bits (379), Expect = 4.783e-45
Identity = 65/135 (48.15%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ ++YSL+++C  +YP+ PP VRF +KI + GV+ +NG++D +  S+L+ W    +I++VL ++R+ M+ KEN KL QP E   +
Sbjct:   27 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGMIIGPPRTIYENRMYSLRVECGPRYPETPPFVRFVTKINLNGVHNSNGVVDMRAVSSLAKWQNSYSIRVVLQELRRLMMCKENMKLPQPPEGQIY 161
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Zebrafish
Match: ube2d1b (ubiquitin-conjugating enzyme E2D 1b [Source:ZFIN;Acc:ZDB-GENE-030131-2735])

HSP 1 Score: 58.151 bits (139), Expect = 3.128e-10
Identity = 36/105 (34.29%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  +      S G V DD   + +W   I+GPS SPY G ++ L I     YP +PP V FT+KI    +N    + +D  R    S W+   T+  VL  I
Sbjct:    9 ELQDLQRDPPAQCSAGPVGDD---LFHWQATIMGPSDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR----SQWSPALTVSKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Zebrafish
Match: ube2d2 (ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-120312-1])

HSP 1 Score: 55.8398 bits (133), Expect = 2.237e-9
Identity = 36/105 (34.29%), Postives = 50/105 (47.62%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL +  +      S G V DD   M +W   I+GP+ SPY G ++ L I     YP +PP V FT++I    +N    + +D  R    S W+   TI  VL  I
Sbjct:    9 ELHDLGRDPPAQCSAGPVGDD---MFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Zebrafish
Match: ube2d3 (ubiquitin-conjugating enzyme E2D 3 [Source:ZFIN;Acc:ZDB-GENE-030131-551])

HSP 1 Score: 55.4546 bits (132), Expect = 3.253e-9
Identity = 35/105 (33.33%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL +  +      S G V DD   + +W   I+GP++SPY G ++ L I     YP +PP V FT++I    +N    + +D  R    S W+   TI  VL  I
Sbjct:    9 ELTDLARDPPAQCSAGPVGDD---VFHWQATIMGPNESPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Xenopus
Match: krt78.7 (keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876590])

HSP 1 Score: 159.458 bits (402), Expect = 1.394e-48
Identity = 70/141 (49.65%), Postives = 101/141 (71.63%), Query Frame = 2 
Query:   62 FTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +T+   +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP +RF +KI M GVN +NG++D +  S L+ W    +IK++L ++R+ M+ KEN KL QP E   +
Sbjct:    4 YTICVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKVECGPKYPEAPPFIRFVTKINMNGVNNSNGVVDPRTISVLAKWQNSYSIKVILQEMRRLMMSKENMKLPQPPEGQCY 144
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Xenopus
Match: cnot7 (CCR4-NOT transcription complex subunit 7 [Source:Xenbase;Acc:XB-GENE-969324])

HSP 1 Score: 159.073 bits (401), Expect = 4.238e-48
Identity = 75/154 (48.70%), Postives = 106/154 (68.83%), Query Frame = 2 
Query:   26 LNFDFKLLDI-YIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            LN   K + + +  T+   +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PPTVRF +K+ M G+N +NG +D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E  T+
Sbjct:   15 LNLALKPVCLTHSATVGVKMPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKIECGPKYPEAPPTVRFVTKMNMNGINNSNGTVDSRSIPVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQTY 168
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Xenopus
Match: krt78.7 (keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876590])

HSP 1 Score: 157.147 bits (396), Expect = 8.745e-48
Identity = 70/139 (50.36%), Postives = 100/139 (71.94%), Query Frame = 2 
Query:   68 MSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +S  +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP +RF +KI M GVN +NG++D +  S L+ W    +IK++L ++R+ M+ KEN KL QP E   +
Sbjct:    1 VSVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKVECGPKYPEAPPFIRFVTKINMNGVNNSNGVVDPRTISVLAKWQNSYSIKVILQEMRRLMMSKENMKLPQPPEGQCY 139
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Xenopus
Match: krt78.7 (keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876590])

HSP 1 Score: 157.147 bits (396), Expect = 1.077e-47
Identity = 72/141 (51.06%), Postives = 102/141 (72.34%), Query Frame = 2 
Query:   65 TMSAV-IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            T+S V +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP +RF +KI M GVN +NG++D +  S L+ W    +IK++L ++R+ M+ KEN KL QP E   +
Sbjct:    5 TVSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKVECGPKYPEAPPFIRFVTKINMNGVNNSNGVVDPRTISVLAKWQNSYSIKVILQEMRRLMMSKENMKLPQPPEGQCY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Xenopus
Match: krt78.7 (keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876590])

HSP 1 Score: 157.147 bits (396), Expect = 1.104e-47
Identity = 70/139 (50.36%), Postives = 99/139 (71.22%), Query Frame = 2 
Query:   68 MSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            M   +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP +RF +KI M GVN +NG++D +  S L+ W    +IK++L ++R+ M+ KEN KL QP E   +
Sbjct:    5 MGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKVECGPKYPEAPPFIRFVTKINMNGVNNSNGVVDPRTISVLAKWQNSYSIKVILQEMRRLMMSKENMKLPQPPEGQCY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Mouse
Match: Ube2v2 (ubiquitin-conjugating enzyme E2 variant 2 [Source:MGI Symbol;Acc:MGI:1917870])

HSP 1 Score: 157.147 bits (396), Expect = 8.730e-48
Identity = 68/135 (50.37%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP+VRF +KI M G+N ++G++D +    L+ W    +IK++L ++R+ M+ KEN KL QP E  T+
Sbjct:    9 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGSKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVILQELRRLMMSKENMKLPQPPEGQTY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Mouse
Match: Ube2v1 (ubiquitin-conjugating enzyme E2 variant 1 [Source:MGI Symbol;Acc:MGI:1913839])

HSP 1 Score: 155.606 bits (392), Expect = 2.712e-47
Identity = 67/135 (49.63%), Postives = 100/135 (74.07%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP+VRF +++ M GV+ +NG++D +  + L+ W   ++IK++L ++R+ M+ KEN KL QP E   +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRVNMSGVSSSNGVVDPRATAVLAKWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Mouse
Match: Ube2v1 (ubiquitin-conjugating enzyme E2 variant 1 [Source:MGI Symbol;Acc:MGI:1913839])

HSP 1 Score: 155.221 bits (391), Expect = 9.010e-47
Identity = 67/135 (49.63%), Postives = 100/135 (74.07%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP+VRF +++ M GV+ +NG++D +  + L+ W   ++IK++L ++R+ M+ KEN KL QP E   +
Sbjct:   37 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRVNMSGVSSSNGVVDPRATAVLAKWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCY 171
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Mouse
Match: Gm20431 (predicted gene 20431 [Source:MGI Symbol;Acc:MGI:5141896])

HSP 1 Score: 157.532 bits (397), Expect = 2.557e-45
Identity = 68/143 (47.55%), Postives = 102/143 (71.33%), Query Frame = 2 
Query:   56 YIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +  T    +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP+VRF +++ M GV+ +NG++D +  + L+ W   ++IK++L ++R+ M+ KEN KL QP E   +
Sbjct:  227 FCITTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRVNMSGVSSSNGVVDPRATAVLAKWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCY 369
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Mouse
Match: Ube2v2 (ubiquitin-conjugating enzyme E2 variant 2 [Source:MGI Symbol;Acc:MGI:1917870])

HSP 1 Score: 114.775 bits (286), Expect = 6.147e-32
Identity = 46/102 (45.10%), Postives = 72/102 (70.59%), Query Frame = 2 
Query:  176 TMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PP+VRF +KI M G+N ++G++D +    L+ W    +IK++L ++R+ M+ KEN KL QP E  T+
Sbjct:    2 TLTRWTGMIIGPPRTNYENRIYSLKVECGSKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVILQELRRLMMSKENMKLPQPPEGQTY 103
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. UniProt/SwissProt
Match: sp|O45495|UB2V1_CAEEL (Ubiquitin-conjugating enzyme E2 variant 1 OS=Caenorhabditis elegans OX=6239 GN=uev-1 PE=1 SV=1)

HSP 1 Score: 167.162 bits (422), Expect = 4.947e-51
Identity = 79/136 (58.09%), Postives = 101/136 (74.26%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKG-MLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KGK DG ISWGL DD D T+T W   I+GP ++PY+ +IY+L+I C   YP EPPTVRFT+K+ MVGVN++NG+IDK+  +TL +W+    IK VL DIRK  M+ KEN KL QPAE + F
Sbjct:    4 VPRNFRLLEELEEGQKGKGDGNISWGLEDDSDMTLTRWTASIIGPPRTPYESRIYNLQIQCGGNYPREPPTVRFTTKVHMVGVNQSNGVIDKRNLTTLRNWSNSYMIKTVLEDIRKNMMMAKENLKLQQPAEGAMF 139
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. UniProt/SwissProt
Match: sp|Q5F3Z3|UB2V2_CHICK (Ubiquitin-conjugating enzyme E2 variant 2 OS=Gallus gallus OX=9031 GN=UBE2V2 PE=2 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 2.704e-48
Identity = 71/135 (52.59%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLK++C  KYP+ PPTVRF +KI M G+N +NG++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E  T+
Sbjct:    8 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPTVRFVTKINMNGINNSNGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTY 142
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. UniProt/SwissProt
Match: sp|Q6PEH5|UB2V2_DANRE (Ubiquitin-conjugating enzyme E2 variant 2 OS=Danio rerio OX=7955 GN=ube2v2 PE=2 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 2.820e-48
Identity = 71/135 (52.59%), Postives = 100/135 (74.07%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP+++ Y+ +IYSLK++C  KYP+ PPTVRF +KI M G+N +NG++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E  T+
Sbjct:    9 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPARTNYENRIYSLKVECGPKYPEVPPTVRFVTKISMNGINNSNGMVDARSIPILAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. UniProt/SwissProt
Match: sp|Q90879|UB2V1_CHICK (Ubiquitin-conjugating enzyme E2 variant 1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=2 SV=2)

HSP 1 Score: 158.688 bits (400), Expect = 1.284e-47
Identity = 73/140 (52.14%), Postives = 99/140 (70.71%), Query Frame = 2 
Query:   65 TMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            T    +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP VRF +KI M GVN +NG++D +  S L+ W    +IK+VL ++R+ M+ KEN KL QP E   +
Sbjct:    4 TTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. UniProt/SwissProt
Match: sp|Q13404|UB2V1_HUMAN (Ubiquitin-conjugating enzyme E2 variant 1 OS=Homo sapiens OX=9606 GN=UBE2V1 PE=1 SV=2)

HSP 1 Score: 158.303 bits (399), Expect = 2.154e-47
Identity = 72/135 (53.33%), Postives = 98/135 (72.59%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ +IYSLKI+C  KYP+ PP VRF +KI M GVN +NG++D +  S L+ W    +IK+VL ++R+ M+ KEN KL QP E   +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. TrEMBL
Match: A0A183P355 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS8791 PE=4 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 3.565e-54
Identity = 83/147 (56.46%), Postives = 112/147 (76.19%), Query Frame = 2 
Query:   44 LLDIYIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +L + +F  +  +PR+FYLLDELE+G KG ++G+ISWGL +  D T+T WNGMI+GP+++P++ +IY L+I+C  KYPD PPTVRF +KIRM GVNE  G +D + FSTLS+WTRG  I+ VL D+RK M   ENS+L QP E+STF
Sbjct:    1 MLFMLLFGFTVCVPRNFYLLDELEQGQKGSQEGSISWGLENMADATLTKWNGMILGPTRTPFENRIYDLRIECGPKYPDIPPTVRFVTKIRMHGVNENTGEVDPRMFSTLSNWTRGYCIRHVLLDVRKKMSASENSRLAQPPENSTF 147
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. TrEMBL
Match: A0A2P6KT92 (Ube2v2 OS=Nephila clavipes OX=2585209 GN=NCL1_29050 PE=4 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 1.012e-53
Identity = 81/146 (55.48%), Postives = 108/146 (73.97%), Query Frame = 2 
Query:   47 LDIYIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            + + IF    V+PR+F LL+ELE+G KG  DGTISWGL DD D T+T W GMI+GP ++PY+ +IYSLK++C  +YPDEPPTVRF SKI+M GV+E++G +DK+    LSHW R  +IK VL ++R+ M  KEN +L+QP E S F
Sbjct:    1 MRLVIFKKGVVVPRNFRLLEELEQGQKGVGDGTISWGLEDDSDMTLTQWTGMIIGPPRTPYENRIYSLKVECGLQYPDEPPTVRFISKIKMTGVSESSGTVDKRTLPVLSHWQRNYSIKTVLQELRRAMTLKENQRLSQPPEGSAF 146
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. TrEMBL
Match: A0A430QSN1 (Ubiquitin-conjugating enzyme E2 variant OS=Schistosoma bovis OX=6184 GN=DC041_0009246 PE=4 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.246e-53
Identity = 82/144 (56.94%), Postives = 110/144 (76.39%), Query Frame = 2 
Query:   53 IYIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            + +F  +  +PR+FYLLDELE+G KG ++G+ISWGL +  D T+T WNGMI+GP+++P++ +IY L+I+C  KYPD PPTVRF +KIRM GVNE  G +D + FSTLS+WTRG  I+ VL D+RK M   ENS+L QP E+STF
Sbjct:    1 MLLFGFTVCVPRNFYLLDELEQGQKGSQEGSISWGLENMADATLTKWNGMILGPTRTPFENRIYDLRIECGPKYPDIPPTVRFVTKIRMHGVNENTGEVDPRMFSTLSNWTRGYCIRHVLLDVRKKMSASENSRLAQPPENSTF 144
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. TrEMBL
Match: A0A183KYU9 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS20246 PE=4 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.246e-53
Identity = 82/144 (56.94%), Postives = 110/144 (76.39%), Query Frame = 2 
Query:   53 IYIFTMSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            + +F  +  +PR+FYLLDELE+G KG ++G+ISWGL +  D T+T WNGMI+GP+++P++ +IY L+I+C  KYPD PPTVRF +KIRM GVNE  G +D + FSTLS+WTRG  I+ VL D+RK M   ENS+L QP E+STF
Sbjct:    1 MLLFGFTVCVPRNFYLLDELEQGQKGSQEGSISWGLENMADATLTKWNGMILGPTRTPFENRIYDLRIECGPKYPDIPPTVRFVTKIRMHGVNENTGEVDPRMFSTLSNWTRGYCIRHVLLDVRKKMSASENSRLAQPPENSTF 144
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. TrEMBL
Match: A0A3Q1C7M4 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Amphiprion ocellaris OX=80972 PE=4 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 2.607e-53
Identity = 79/138 (57.25%), Postives = 105/138 (76.09%), Query Frame = 2 
Query:   71 SAVIPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            S V+PRSF LL+ELEEG KG  DGT+SWGL DDDD T+T+WNGMI+GP+K+ YDG+IYSLKIDC  +YP+ PP VRF +KI + GVN +NG++D K  + LS W     I+MVL ++R+ M+ KEN++L+QP E   +
Sbjct:    6 SVVVPRSFRLLEELEEGQKGGGDGTVSWGLADDDDMTLTHWNGMIIGPAKTVYDGRIYSLKIDCGTRYPEHPPHVRFVNKINLTGVNSSNGVVDIKSVTALSRWKNSYNIRMVLQELRQHMMMKENNRLSQPPEGQVY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Cavefish
Match: ube2v2 (ubiquitin conjugating enzyme E2 V2 [Source:NCBI gene;Acc:103033870])

HSP 1 Score: 159.844 bits (403), Expect = 5.044e-49
Identity = 71/135 (52.59%), Postives = 100/135 (74.07%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP+++ Y+ +IYSLK++C  KYP+ PPTVRF +KI M G+N +NG++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E  T+
Sbjct:    9 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPARTNYENRIYSLKVECGPKYPELPPTVRFVTKISMNGINNSNGMVDARSIPILTKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTY 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Cavefish
Match: ube2v1 (ubiquitin-conjugating enzyme E2 variant 1 [Source:NCBI gene;Acc:103044311])

HSP 1 Score: 150.984 bits (380), Expect = 1.776e-45
Identity = 66/135 (48.89%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ ++YSL+++C  KYP+ PP VRF +KI + GV+ +NG++D +  S+L+ W    +I++VL ++R+ M+ KEN KL QP E   +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGMIIGPPRTIYENRMYSLRVECGPKYPETPPFVRFVTKINLNGVHNSNGVVDMRAVSSLAKWQNSYSIRVVLQELRRLMMCKENMKLPQPPEGQIY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Cavefish
Match: ENSAMXT00000034419.1 (ubiquitin-conjugating enzyme E2 variant 1-like [Source:NCBI gene;Acc:103028786])

HSP 1 Score: 150.214 bits (378), Expect = 3.624e-45
Identity = 65/135 (48.15%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP ++ Y+ ++YSL+++C  +YP+ PP VRF +KI + GV+ +NG++D +  S+L+ W    +I++VL ++R+ M+ KEN KL QP E   +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGMIIGPPRTIYENRMYSLRVECGPRYPETPPFVRFVTKINLNGVHNSNGVVDTRAVSSLAKWQNSYSIRVVLQELRRLMMCKENMKLPQPPEGQIY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Cavefish
Match: ENSAMXT00000046207.1 (ubiquitin-conjugating enzyme E2 variant 1-like [Source:NCBI gene;Acc:103028786])

HSP 1 Score: 68.1662 bits (165), Expect = 2.262e-13
Identity = 30/47 (63.83%), Postives = 38/47 (80.85%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSK 217
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W GMI+GP +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGMIIGPPR 57
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Cavefish
Match: ube2d1b (ubiquitin conjugating enzyme E2 D1 [Source:NCBI gene;Acc:103029965])

HSP 1 Score: 58.151 bits (139), Expect = 2.651e-10
Identity = 36/105 (34.29%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  +      S G V DD   + +W   I+GPS SPY G ++ L I     YP +PP V FT+KI    +N    + +D  R    S W+   T+  VL  I
Sbjct:    9 ELQDLQRDPPAQCSAGPVGDD---LFHWQATIMGPSDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR----SQWSPALTVSKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003439.1 (pep scaffold:Pmarinus_7.0:GL492337:1118:2976:1 gene:ENSPMAG00000003150.1 transcript:ENSPMAT00000003439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.3882 bits (150), Expect = 3.301e-13
Identity = 28/42 (66.67%), Postives = 34/42 (80.95%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMI 202
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D TMT W GM+
Sbjct:   22 VPRNFCLLEELEEGQKGVGDGTVSWGLEDDEDMTMTRWTGMV 63
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010378.1 (pep scaffold:Pmarinus_7.0:GL477318:26908:31295:-1 gene:ENSPMAG00000009396.1 transcript:ENSPMAT00000010378.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.8398 bits (133), Expect = 4.679e-10
Identity = 37/114 (32.46%), Postives = 54/114 (47.37%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            +P +  L  EL +  +      S G V DD   + +W   I+GP+ SPY G ++ L I     YP +PP V FT++I    +N    + +D  R    S W+   TI  VL  I
Sbjct:    1 MPPTRPLHQELNDLGRDPPAQCSAGPVGDD---LFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 107
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006211.1 (pep scaffold:Pmarinus_7.0:GL476897:3176:4886:1 gene:ENSPMAG00000005612.1 transcript:ENSPMAT00000006211.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 1.394e-8
Identity = 20/41 (48.78%), Postives = 30/41 (73.17%), Query Frame = 2 
Query:  188 WNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKI 310
            WN +I GP  +P++   + L I+ TE+YP++PPTVRF SK+
Sbjct:   24 WNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKM 64
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008817.1 (pep scaffold:Pmarinus_7.0:GL476329:1748443:1760143:-1 gene:ENSPMAG00000007968.1 transcript:ENSPMAT00000008817.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.2914 bits (116), Expect = 8.382e-8
Identity = 18/41 (43.90%), Postives = 30/41 (73.17%), Query Frame = 2 
Query:  188 WNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKI 310
            WN +I GP  +P++   + L ++ TE+YP++PPTV+F SK+
Sbjct:   36 WNAVIFGPEGTPFEDGTFKLTLEFTEEYPNKPPTVKFVSKM 76
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Sea Lamprey
Match: ube2na (ubiquitin-conjugating enzyme E2Na [Source:ZFIN;Acc:ZDB-GENE-040426-2873])

HSP 1 Score: 46.2098 bits (108), Expect = 3.608e-7
Identity = 19/51 (37.25%), Postives = 32/51 (62.75%), Query Frame = 2 
Query:  158 VDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKI 310
             + D+    Y++ +I GP+ SP++G  + L++   E+YP  PP VRF +KI
Sbjct:   26 AEPDESNARYFHVVIAGPADSPFEGGTFKLELFLPEEYPMAPPKVRFMTKI 76
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Yeast
Match: MMS2 (Ubiquitin-conjugating enzyme variant; involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003055])

HSP 1 Score: 127.102 bits (318), Expect = 3.117e-37
Identity = 67/135 (49.63%), Postives = 84/135 (62.22%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELE+G KG    + S+GL D DD TMT WNG I+GP  S ++ +IYSL IDC   YPD PP V F SKI +  VN T G + +  F TL  W R  T++ +L D+RK M    N KL QP E  TF
Sbjct:    4 VPRNFRLLEELEKGEKGFGPESCSYGLADSDDITMTKWNGTILGPPHSNHENRIYSLSIDCGPNYPDSPPKVTFISKINLPCVNPTTGEV-QTDFHTLRDWKRAYTMETLLLDLRKEMATPANKKLRQPKEGETF 137
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Yeast
Match: UBC5 (Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466])

HSP 1 Score: 53.5286 bits (127), Expect = 1.635e-9
Identity = 35/105 (33.33%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNET-NGLIDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL +  +    + S G V DD   + +W   I+GPS SPY G ++ L I     YP +PP V FT+KI    +N + N  +D  +      W+   T+  VL  I
Sbjct:   10 ELSDLGRDPPASCSAGPVGDD---LYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILK----DQWSPALTLSKVLLSI 107
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Yeast
Match: UBC4 (Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286])

HSP 1 Score: 51.2174 bits (121), Expect = 1.188e-8
Identity = 33/105 (31.43%), Postives = 50/105 (47.62%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNET-NGLIDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL +  +    + S G V DD   + +W   I+GP+ SPY G ++ L I     YP +PP + FT+KI    +N   N  +D  +      W+   T+  VL  I
Sbjct:   10 ELSDLERDPPTSCSAGPVGDD---LYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILK----DQWSPALTLSKVLLSI 107
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Yeast
Match: UBC11 (Ubiquitin-conjugating enzyme; most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2 [Source:SGD;Acc:S000005866])

HSP 1 Score: 50.447 bits (119), Expect = 2.604e-8
Identity = 29/94 (30.85%), Postives = 51/94 (54.26%), Query Frame = 2 
Query:   98 LLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL---IDKKRFSTL 370
            L +EL + +     +IS   VDD+D  +TYW G I GP  +PY G  + + +   + YP  PP ++F S +    V+++  +   I K+++S +
Sbjct:   13 LQNELLQLLSSTTESISAFPVDDND--LTYWVGYITGPKDTPYSGLKFKVSLKFPQNYPFHPPMIKFLSPMWHPNVDKSGNICLDILKEKWSAV 104
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Yeast
Match: RAD6 (Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026])

HSP 1 Score: 47.7506 bits (112), Expect = 2.816e-7
Identity = 28/98 (28.57%), Postives = 49/98 (50.00%), Query Frame = 2 
Query:  188 WNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            WN MI+GP+ +PY+   + L ++  E+YP++PP V+F S++    V   NG I        + WT    +  +L+ I + +    N       E++T 
Sbjct:   36 WNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVY-ANGEICLDILQ--NRWTPTYDVASILTSI-QSLFNDPNPASPANVEAATL 129
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Nematostella
Match: EDO30421 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0T9])

HSP 1 Score: 154.066 bits (388), Expect = 2.842e-47
Identity = 70/134 (52.24%), Postives = 98/134 (73.13%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LLDELEEG KG DGT+SWGL  DDD  +  WNGMI+GP+++ ++ +IY+LKI C   YP +PPTV+F SKI M GVN + G +++++   LS W +G +IK +L+ +RK M +K+N KL QP E ST+
Sbjct:    9 VPRNFRLLDELEEGQKGGDGTVSWGLESDDDMELYRWNGMILGPARTVFENRIYNLKIVCGPNYPQKPPTVKFVSKINMNGVN-SKGEVEERQHPLLSRWNQGESIKSILTSLRKQMTEKQNCKLQQPPEGSTY 141
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Nematostella
Match: EDO43669 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXR8])

HSP 1 Score: 56.225 bits (134), Expect = 4.484e-10
Identity = 36/105 (34.29%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  +      S G V DD   + +W   I+GP+ SPY G ++ L I     YP +PP V FT+KI    +N    + +D  R    S W+   TI  VL  I
Sbjct:    9 ELQDLGRDPPAQCSAGPVGDD---LFHWQATIMGPADSPYQGGVFFLTIHFPTDYPFKPPKVSFTTKIYHPNINSNGSICLDILR----SQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Nematostella
Match: EDO39550 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q6])

HSP 1 Score: 50.0618 bits (118), Expect = 1.887e-7
Identity = 29/91 (31.87%), Postives = 43/91 (47.25%), Query Frame = 2 
Query:  170 DPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKE 442
            D T T   G I GP ++P++G  Y+L I   E YP  PP V+FT+KI    ++   G I          W    T++ V+  I+  +   E
Sbjct:   33 DETFTKLKGEIRGPPETPFEGGTYNLDIVIPETYPFNPPKVKFTTKIWHPNISSVTGAICLDILK--DQWAAAMTLRTVMLSIQALLASPE 121
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Medaka
Match: ENSORLT00000012514.2 (ubiquitin-conjugating enzyme E2 variant 1 [Source:NCBI gene;Acc:101155761])

HSP 1 Score: 164.851 bits (416), Expect = 6.013e-51
Identity = 73/135 (54.07%), Postives = 100/135 (74.07%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DG +SWGL +D+D  +++WNGMI+GP K+ Y+G++YSLKIDC  +YP+ PP VRF +KI M GVN + G++D K   +LS W   N IKMVL ++R+ M+ KENS+L+QP E   F
Sbjct:   11 VPRNFRLLEELEEGQKGGGDGIVSWGLENDEDMMLSHWNGMIIGPPKTVYEGRMYSLKIDCGSRYPEHPPHVRFINKINMTGVNSSTGVVDLKSVPSLSRWKNSNNIKMVLLELRQHMMLKENSRLSQPPEGQVF 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Medaka
Match: ube2v2 (ubiquitin conjugating enzyme E2 V2 [Source:NCBI gene;Acc:101173013])

HSP 1 Score: 158.688 bits (400), Expect = 1.300e-48
Identity = 70/135 (51.85%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG+ DGT+SWGL DDDD T+T W GMI+GP+++ Y+ +IYSLK++C  +YP+  PTVRF +KI M G+N +NG++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E   F
Sbjct:    9 VPRNFRLLEELEEGQKGEGDGTVSWGLEDDDDMTLTRWTGMIIGPARTNYENRIYSLKVECGPRYPETAPTVRFVTKISMNGINNSNGMVDSRSIPILAKWQNSYSIKIVLQELRRLMMSKENMKLPQPPEGQIF 143
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Medaka
Match: ube2v2 (ubiquitin conjugating enzyme E2 V2 [Source:NCBI gene;Acc:101173013])

HSP 1 Score: 159.073 bits (401), Expect = 3.006e-48
Identity = 70/135 (51.85%), Postives = 99/135 (73.33%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKGK-DGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG+ DGT+SWGL DDDD T+T W GMI+GP+++ Y+ +IYSLK++C  +YP+  PTVRF +KI M G+N +NG++D +    L+ W    +IK+VL ++R+ M+ KEN KL QP E   F
Sbjct:   41 VPRNFRLLEELEEGQKGEGDGTVSWGLEDDDDMTLTRWTGMIIGPARTNYENRIYSLKVECGPRYPETAPTVRFVTKISMNGINNSNGMVDSRSIPILAKWQNSYSIKIVLQELRRLMMSKENMKLPQPPEGQIF 175
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Medaka
Match: ENSORLT00000018878.2 (pep primary_assembly:ASM223467v1:7:21895490:21901902:1 gene:ENSORLG00000022116.1 transcript:ENSORLT00000018878.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 145.206 bits (365), Expect = 2.768e-43
Identity = 65/139 (46.76%), Postives = 96/139 (69.06%), Query Frame = 2 
Query:   68 MSAVIPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            M   +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W G+I+GP ++ Y+ ++Y+LK++C   YP+ PP VRF +KI + GV+ +NG++D    + L+ W    +I+MVL ++R+ M  KEN KL QP E   +
Sbjct:    1 MCVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGVILGPPRTSYENRMYNLKVECGPGYPESPPFVRFVTKINLNGVHNSNGVVDMHAVTALAKWQNSYSIRMVLLELRRLMTCKENMKLPQPPEGQIY 139
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Medaka
Match: ENSORLT00000029461.1 (pep primary_assembly:ASM223467v1:7:21894091:21904217:1 gene:ENSORLG00000022116.1 transcript:ENSORLT00000029461.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 143.665 bits (361), Expect = 1.102e-42
Identity = 64/135 (47.41%), Postives = 95/135 (70.37%), Query Frame = 2 
Query:   80 IPRSFYLLDELEEGMKG-KDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            +PR+F LL+ELEEG KG  DGT+SWGL DD+D T+T W G+I+GP ++ Y+ ++Y+LK++C   YP+ PP VRF +KI + GV+ +NG++D    + L+ W    +I+MVL ++R+ M  KEN KL QP E   +
Sbjct:   11 VPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWRGVILGPPRTSYENRMYNLKVECGPGYPESPPFVRFVTKINLNGVHNSNGVVDMHAVTALAKWQNSYSIRMVLLELRRLMTCKENMKLPQPPEGQIY 145
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Planmine SMEST
Match: SMESG000062065.1 (SMESG000062065.1)

HSP 1 Score: 284.648 bits (727), Expect = 2.779e-98
Identity = 138/138 (100.00%), Postives = 138/138 (100.00%), Query Frame = 2 
Query:   68 MSAVIPRSFYLLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 481
            MSAVIPRSFYLLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF
Sbjct:    1 MSAVIPRSFYLLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF 138
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Planmine SMEST
Match: SMESG000063640.1 (SMESG000063640.1)

HSP 1 Score: 55.8398 bits (133), Expect = 1.536e-9
Identity = 36/104 (34.62%), Postives = 52/104 (50.00%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL+  M       S G  + D   + +W+  I+GP+ SPY+G I+SL I+    YP +PP V+F +KI    +N +NG I          W+   TI  VL  I
Sbjct:    9 ELKSLMTDPPAQCSAGPKESD---LVHWSATIMGPADSPYEGGIFSLSIEFPPDYPFKPPMVKFDTKIFHPNIN-SNGSICLDILK--GQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Planmine SMEST
Match: SMESG000064169.1 (SMESG000064169.1)

HSP 1 Score: 55.8398 bits (133), Expect = 1.630e-9
Identity = 35/105 (33.33%), Postives = 51/105 (48.57%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGL-IDKKRFSTLSHWTRGNTIKMVLSDI 418
            EL++  K      S G + +D   + +W   I+GP+ SPYDG ++ L I     YP +PP V FT+KI    +N    + +D  R      W+   TI  VL  I
Sbjct:    9 ELQDLAKDPPAQCSAGPMHED---LFHWQATIMGPNDSPYDGGVFFLDIQFPTDYPFKPPKVTFTTKIYHPNINANGSICLDILR----GQWSPALTISKVLLSI 106
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Planmine SMEST
Match: SMESG000016630.1 (SMESG000016630.1)

HSP 1 Score: 53.9138 bits (128), Expect = 1.021e-8
Identity = 32/112 (28.57%), Postives = 52/112 (46.43%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKE 442
            E +E MK  +   S   V   +  + + NG IVGP ++PY+G  + L I   E YP  PP V+F ++I    ++   G+I          W    +++ VL  I+  +   E
Sbjct:   12 EFKELMKSPESVSSQLKVKPINDNLMHMNGTIVGPPETPYEGAEFVLDIVIPENYPFVPPKVKFLTRIWHPNISSATGVICLDILK--DQWAAAMSLRTVLLSIQALLASPE 121
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Planmine SMEST
Match: SMESG000016608.1 (SMESG000016608.1)

HSP 1 Score: 53.9138 bits (128), Expect = 1.021e-8
Identity = 32/112 (28.57%), Postives = 52/112 (46.43%), Query Frame = 2 
Query:  107 ELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSKSPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFSTLSHWTRGNTIKMVLSDIRKGMLQKE 442
            E +E MK  +   S   V   +  + + NG IVGP ++PY+G  + L I   E YP  PP V+F ++I    ++   G+I          W    +++ VL  I+  +   E
Sbjct:   12 EFKELMKSPESVSSQLKVKPINDNLMHMNGTIVGPPETPYEGAEFVLDIVIPENYPFVPPKVKFLTRIWHPNISSATGVICLDILK--DQWAAAMSLRTVLLSIQALLASPE 121
The following BLAST results are available for this feature:
BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
UBE2V14.486e-4853.33ubiquitin conjugating enzyme E2 V1 [Source:HGNC Sy... [more]
UBE2V18.945e-4853.33ubiquitin conjugating enzyme E2 V1 [Source:HGNC Sy... [more]
UBE2V18.945e-4853.33ubiquitin conjugating enzyme E2 V1 [Source:HGNC Sy... [more]
UBE2V21.192e-4751.11ubiquitin conjugating enzyme E2 V2 [Source:HGNC Sy... [more]
TMEM189-UBE2V13.082e-4651.05TMEM189-UBE2V1 readthrough [Source:HGNC Symbol;Acc... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
uev-13.889e-5258.09Ubiquitin-conjugating enzyme E2 variant 1 [Source... [more]
uev-13.889e-5258.09Ubiquitin-conjugating enzyme E2 variant 1 [Source... [more]
let-701.168e-933.33Ubiquitin-conjugating enzyme E2 2 [Source:UniProt... [more]
ubc-18.235e-741.46Ubiquitin-conjugating enzyme E2 1 [Source:UniProt... [more]
ubc-218.513e-730.59Probable ubiquitin-conjugating enzyme E2 21 [Sour... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Uev1A1.646e-5052.55gene:FBgn0035601 transcript:FBtr0345026[more]
Uev1A1.646e-5052.55gene:FBgn0035601 transcript:FBtr0077155[more]
Uev1A5.703e-3549.02gene:FBgn0035601 transcript:FBtr0077156[more]
eff3.423e-933.33gene:FBgn0011217 transcript:FBtr0310554[more]
eff3.423e-933.33gene:FBgn0011217 transcript:FBtr0336876[more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2v23.735e-4952.59ubiquitin-conjugating enzyme E2 variant 2 [Source:... [more]
ube2v14.783e-4548.15ubiquitin-conjugating enzyme E2 variant 1 [Source:... [more]
ube2d1b3.128e-1034.29ubiquitin-conjugating enzyme E2D 1b [Source:ZFIN;A... [more]
ube2d22.237e-934.29ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog... [more]
ube2d33.253e-933.33ubiquitin-conjugating enzyme E2D 3 [Source:ZFIN;Ac... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
krt78.71.394e-4849.65keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876... [more]
cnot74.238e-4848.70CCR4-NOT transcription complex subunit 7 [Source:X... [more]
krt78.78.745e-4850.36keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876... [more]
krt78.71.077e-4751.06keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876... [more]
krt78.71.104e-4750.36keratin 78, gene 7 [Source:Xenbase;Acc:XB-GENE-876... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ube2v28.730e-4850.37ubiquitin-conjugating enzyme E2 variant 2 [Source:... [more]
Ube2v12.712e-4749.63ubiquitin-conjugating enzyme E2 variant 1 [Source:... [more]
Ube2v19.010e-4749.63ubiquitin-conjugating enzyme E2 variant 1 [Source:... [more]
Gm204312.557e-4547.55predicted gene 20431 [Source:MGI Symbol;Acc:MGI:51... [more]
Ube2v26.147e-3245.10ubiquitin-conjugating enzyme E2 variant 2 [Source:... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O45495|UB2V1_CAEEL4.947e-5158.09Ubiquitin-conjugating enzyme E2 variant 1 OS=Caeno... [more]
sp|Q5F3Z3|UB2V2_CHICK2.704e-4852.59Ubiquitin-conjugating enzyme E2 variant 2 OS=Gallu... [more]
sp|Q6PEH5|UB2V2_DANRE2.820e-4852.59Ubiquitin-conjugating enzyme E2 variant 2 OS=Danio... [more]
sp|Q90879|UB2V1_CHICK1.284e-4752.14Ubiquitin-conjugating enzyme E2 variant 1 OS=Gallu... [more]
sp|Q13404|UB2V1_HUMAN2.154e-4753.33Ubiquitin-conjugating enzyme E2 variant 1 OS=Homo ... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183P3553.565e-5456.46UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A2P6KT921.012e-5355.48Ube2v2 OS=Nephila clavipes OX=2585209 GN=NCL1_2905... [more]
A0A430QSN11.246e-5356.94Ubiquitin-conjugating enzyme E2 variant OS=Schisto... [more]
A0A183KYU91.246e-5356.94UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A3Q1C7M42.607e-5357.25UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2v25.044e-4952.59ubiquitin conjugating enzyme E2 V2 [Source:NCBI ge... [more]
ube2v11.776e-4548.89ubiquitin-conjugating enzyme E2 variant 1 [Source:... [more]
ENSAMXT00000034419.13.624e-4548.15ubiquitin-conjugating enzyme E2 variant 1-like [So... [more]
ENSAMXT00000046207.12.262e-1363.83ubiquitin-conjugating enzyme E2 variant 1-like [So... [more]
ube2d1b2.651e-1034.29ubiquitin conjugating enzyme E2 D1 [Source:NCBI ge... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000003439.13.301e-1366.67pep scaffold:Pmarinus_7.0:GL492337:1118:2976:1 gen... [more]
ENSPMAT00000010378.14.679e-1032.46pep scaffold:Pmarinus_7.0:GL477318:26908:31295:-1 ... [more]
ENSPMAT00000006211.11.394e-848.78pep scaffold:Pmarinus_7.0:GL476897:3176:4886:1 gen... [more]
ENSPMAT00000008817.18.382e-843.90pep scaffold:Pmarinus_7.0:GL476329:1748443:1760143... [more]
ube2na3.608e-737.25ubiquitin-conjugating enzyme E2Na [Source:ZFIN;Acc... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
MMS23.117e-3749.63Ubiquitin-conjugating enzyme variant; involved in ... [more]
UBC51.635e-933.33Ubiquitin-conjugating enzyme; mediates selective d... [more]
UBC41.188e-831.43Ubiquitin-conjugating enzyme (E2); key E2 partner ... [more]
UBC112.604e-830.85Ubiquitin-conjugating enzyme; most similar in sequ... [more]
RAD62.816e-728.57Ubiquitin-conjugating enzyme (E2); involved in pos... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO304212.842e-4752.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436694.484e-1034.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395501.887e-731.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000012514.26.013e-5154.07ubiquitin-conjugating enzyme E2 variant 1 [Source:... [more]
ube2v21.300e-4851.85ubiquitin conjugating enzyme E2 V2 [Source:NCBI ge... [more]
ube2v23.006e-4851.85ubiquitin conjugating enzyme E2 V2 [Source:NCBI ge... [more]
ENSORLT00000018878.22.768e-4346.76pep primary_assembly:ASM223467v1:7:21895490:219019... [more]
ENSORLT00000029461.11.102e-4247.41pep primary_assembly:ASM223467v1:7:21894091:219042... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 variant 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000062065.12.779e-98100.00SMESG000062065.1[more]
SMESG000063640.11.536e-934.62SMESG000063640.1[more]
SMESG000064169.11.630e-933.33SMESG000064169.1[more]
SMESG000016630.11.021e-828.57SMESG000016630.1[more]
SMESG000016608.11.021e-828.57SMESG000016608.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011574 ID=SMED30011574|Name=Ubiquitin-conjugating enzyme E2 variant 2|organism=Schmidtea mediterranea sexual|type=transcript|length=830bp
AGTTATGTTGTTTGTTTATATTTAGTTAAATTTTGATTTTAAGTTATTAG
ATATTTATATATTTACTATGTCTGCTGTTATTCCCAGGAGTTTTTATCTG
TTGGATGAATTGGAAGAAGGCATGAAAGGCAAAGACGGAACTATTAGCTG
GGGATTAGTTGATGATGATGATCCAACAATGACTTATTGGAATGGTATGA
TTGTTGGCCCTTCAAAGTCACCATATGATGGTAAAATCTATTCGTTGAAA
ATAGATTGTACTGAAAAGTACCCAGATGAACCTCCAACAGTTCGTTTTAC
TTCTAAAATTAGAATGGTTGGTGTTAATGAGACTAATGGCTTAATTGATA
AAAAACGGTTTTCGACTCTTAGTCATTGGACTCGCGGTAACACGATTAAA
ATGGTTTTATCTGATATTCGAAAGGGGATGTTGCAGAAAGAAAACTCGAA
ACTAACACAACCAGCCGAATCTTCAACATTTTAAAGTGTAACCAAACTTC
AAGAGATCGTTCTGAATAAATATCCGACACTTTCTTATTTTTTATTGTAA
GAGTTAAATAATTTGATTTGTTTAATCATATTGTCTTTATTTTGCATACT
TTTAAGTATACAAAATAGAAATAATGAAATTTGATTAGTGTTCACTATTA
TGCATAAATTAATTTGACCATGATTTTCTACAACCAAGTGCTAATTTTGA
AAGTAATTATTCCCATTTGTTTACGTTAAAACCTTTGTTTGGTAGCACTG
TTGTGGTATTTTATAAAATGCTTTTCAATTTTGAATATTCCCACATTTTC
ATAAAATAGAAATTACTTTGTCTTGAAAGA
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protein sequence of SMED30011574-orf-1

>SMED30011574-orf-1 ID=SMED30011574-orf-1|Name=SMED30011574-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=139bp
MSAVIPRSFYLLDELEEGMKGKDGTISWGLVDDDDPTMTYWNGMIVGPSK
SPYDGKIYSLKIDCTEKYPDEPPTVRFTSKIRMVGVNETNGLIDKKRFST
LSHWTRGNTIKMVLSDIRKGMLQKENSKLTQPAESSTF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0000729DNA double-strand break processing
GO:0016567protein ubiquitination
GO:0042275error-free postreplication DNA repair
GO:0006301postreplication repair
GO:0070534protein K63-linked ubiquitination
GO:0090325regulation of locomotion involved in locomotory behavior
GO:2000008regulation of protein localization to cell surface
Vocabulary: cellular component
TermDefinition
GO:0005654nucleoplasm
GO:0031372UBC13-MMS2 complex
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005829cytosol
GO:0030425dendrite
GO:0042995cell projection
GO:0043005neuron projection
GO:0043204perikaryon
Vocabulary: molecular function
TermDefinition
GO:0061631ubiquitin conjugating enzyme activity
GO:0031624ubiquitin conjugating enzyme binding
GO:0031625ubiquitin protein ligase binding
GO:0061630ubiquitin protein ligase activity
Vocabulary: INTERPRO
TermDefinition
IPR000608UBQ-conjugat_E2
IPR016135UBQ-conjugating_enzyme/RWD
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableSMARTSM00212ubc_7coord: 9..137
e-value: 1.2E-4
score: 29.6
NoneNo IPR availablePANTHERPTHR24068FAMILY NOT NAMEDcoord: 3..137
NoneNo IPR availablePANTHERPTHR24068:SF169HCG2044781-RELATEDcoord: 3..137
IPR016135Ubiquitin-conjugating enzyme/RWD-likeGENE3DG3DSA:3.10.110.10coord: 1..138
e-value: 1.9E-51
score: 175.6
IPR016135Ubiquitin-conjugating enzyme/RWD-likeSUPERFAMILYSSF54495UBC-likecoord: 4..137
IPR000608Ubiquitin-conjugating enzyme E2PFAMPF00179UQ_concoord: 12..127
e-value: 2.6E-17
score: 62.8
IPR000608Ubiquitin-conjugating enzyme E2PROSITEPS50127UBIQUITIN_CONJUGAT_2coord: 9..138
score: 17.998