Ragulator complex protein isoform 1

Overview
NameRagulator complex protein isoform 1
Smed IDSMED30011568
Length (bp)738
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ragulator complex protein isoform 1 (SMED30011568) t-SNE clustered cells

Violin plots show distribution of expression levels for Ragulator complex protein isoform 1 (SMED30011568) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ragulator complex protein isoform 1 (SMED30011568) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ragulator complex protein isoform 1 (SMED30011568) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011568

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30011568SMESG000081274.1 Contig787GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30011568SMESG000058434.1 Contig787GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30011568SMESG000058434.1 dd_Smed_v4_2623_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011568SMESG000058434.1 dd_Smed_v4_2623_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011568SMESG000058434.1 dd_Smed_v4_2623_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011568SMESG000058434.1 Contig33578newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011568SMESG000058434.1 Contig33578uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011568SMESG000058434.1 Contig34053newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011568SMESG000058434.1 Contig34053uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Human
Match: LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606])

HSP 1 Score: 50.8322 bits (120), Expect = 1.076e-7
Identity = 31/112 (27.68%), Postives = 57/112 (50.89%), Query Frame = 1 
Query:   16 VSDHLRNFLSLS----DGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALE 339
            ++D L+ FL       +G+  I + D+DGV ++KE         ++P   ++F  A  Q SK+ L   K II  Y  + + QFN       P++   + ++ A+ G++++LE
Sbjct:    1 MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKE-------HALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFN-----RLPLVVSFIASSSANTGLIVSLE 100
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Fly
Match: CG5110 (gene:FBgn0032642 transcript:FBtr0080983)

HSP 1 Score: 60.4622 bits (145), Expect = 1.652e-11
Identity = 35/108 (32.41%), Postives = 57/108 (52.78%), Query Frame = 1 
Query:   16 VSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALE 339
            +  +L   L    G+  I + D+DGV +++ + ++NVD  + P    +FT A  Q+SK+ LG  K II+ Y+ + + Q N       P+I   VG    + G +LALE
Sbjct:    5 IKKYLDGLLQKVSGLYVIQITDRDGVPLLRVSQEKNVDFALMPSFIPTFTTACDQASKLGLGRNKTIISMYSNYQVVQMN-----KLPLILTFVGAENCNTGHILALE 107
[Close]
BLAST of Ragulator complex protein isoform 1 vs. Ensembl Fly
Match: CG5110 (gene:FBgn0032642 transcript:FBtr0306162)

HSP 1 Score: 60.4622 bits (145), Expect = 1.652e-11
Identity = 35/108 (32.41%), Postives = 57/108 (52.78%), Query Frame = 1 
Query:   16 VSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALE 339
            +  +L   L    G+  I + D+DGV +++ + ++NVD  + P    +FT A  Q+SK+ LG  K II+ Y+ + + Q N       P+I   VG    + G +LALE
Sbjct:    5 IKKYLDGLLQKVSGLYVIQITDRDGVPLLRVSQEKNVDFALMPSFIPTFTTACDQASKLGLGRNKTIISMYSNYQVVQMN-----KLPLILTFVGAENCNTGHILALE 107
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BLAST of Ragulator complex protein isoform 1 vs. UniProt/SwissProt
Match: sp|Q9VJD2|LTOR3_DROME (Ragulator complex protein LAMTOR3 homolog OS=Drosophila melanogaster OX=7227 GN=CG5110 PE=2 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 1.656e-10
Identity = 35/108 (32.41%), Postives = 57/108 (52.78%), Query Frame = 1 
Query:   16 VSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALE 339
            +  +L   L    G+  I + D+DGV +++ + ++NVD  + P    +FT A  Q+SK+ LG  K II+ Y+ + + Q N       P+I   VG    + G +LALE
Sbjct:    5 IKKYLDGLLQKVSGLYVIQITDRDGVPLLRVSQEKNVDFALMPSFIPTFTTACDQASKLGLGRNKTIISMYSNYQVVQMN-----KLPLILTFVGAENCNTGHILALE 107
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BLAST of Ragulator complex protein isoform 1 vs. TrEMBL
Match: A0A4S2LA25 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009170 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 7.039e-29
Identity = 53/126 (42.06%), Postives = 86/126 (68.25%), Query Frame = 1 
Query:   19 SDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFAR-DPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKM 393
            +D+L+ FLS  DGIIG+++ DKDGV+M   + ++  DQ +QP++ T+F ++IQQSSK+ +G  ++++TRY   VICQFN+A   P  P+   +VG+N  D+G +LA EP I  ++   +   SS++
Sbjct:    6 TDYLKRFLSDVDGIIGLYVSDKDGVIMASVSSEDMPDQAIQPYVATTFLSSIQQSSKLEMGALEWMVTRYEYMVICQFNYATARPPLPLFLTIVGSNNCDLGAILATEPSIRPLITRLAAHVSSRL 131
[Close]
BLAST of Ragulator complex protein isoform 1 vs. TrEMBL
Match: Q86EA8 (Clone ZZD612 mRNA sequence OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 1.102e-27
Identity = 53/129 (41.09%), Postives = 86/129 (66.67%), Query Frame = 1 
Query:   13 AVSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDH 399
            +  DHL+ FLS  DGI+GIF+ DKDGVV+   T+D+  DQ   P++  +F  ++QQ +K++LG  +++IT Y E VICQF+F    + P+   VVG++  ++G ++ALEP I  ++   +P ASS++ +
Sbjct:    4 SACDHLKRFLSEVDGILGIFVADKDGVVVASATMDDMPDQARSPYVTAAFIVSLQQVNKLDLGELEWMITSYQEMVICQFHFTCRLALPLFLTVVGSSECNIGAVIALEPSIRPLLNRLAPEASSRIQN 132
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BLAST of Ragulator complex protein isoform 1 vs. TrEMBL
Match: A0A183QHU2 (Uncharacterized protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 1.365e-27
Identity = 52/129 (40.31%), Postives = 87/129 (67.44%), Query Frame = 1 
Query:   13 AVSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDH 399
            +  D+L+ FLS  DGI+GIF+ DKDGVV+   T+D+  DQ   P++  +F  ++QQ +K++LG+ +++IT Y E VICQF+F    + P+   VVG++  ++G ++ALEP I  ++   +P ASS++ +
Sbjct:    4 SACDYLKRFLSEVDGILGIFVADKDGVVVASATMDDMPDQARSPYVTAAFIVSLQQVNKLDLGDLEWMITSYQEMVICQFHFTCQSALPLFLTVVGSSECNIGAIIALEPSIRPLLNRLAPEASSRIQN 132
[Close]
BLAST of Ragulator complex protein isoform 1 vs. TrEMBL
Match: G4LWW9 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 GN=Smp_041500 PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 2.542e-27
Identity = 51/129 (39.53%), Postives = 87/129 (67.44%), Query Frame = 1 
Query:   13 AVSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDH 399
            +  D+L+ FLS  DGI+GIF+ DKDGVV+   T+D+  DQ   P++  +F  ++QQ +K++LG+ +++IT Y E V+CQF+F    + P+   VVG++  ++G ++ALEP I  ++   +P ASS++ +
Sbjct:    4 SACDYLKRFLSEVDGILGIFVADKDGVVVASATMDDMPDQARSPYVTAAFIVSLQQVNKLDLGDLEWMITSYQEMVVCQFHFTCQSALPLFLTVVGSSECNIGAIIALEPSIRPLLNRLAPEASSRIQN 132
[Close]
BLAST of Ragulator complex protein isoform 1 vs. TrEMBL
Match: A0A4Z2D432 (Ragulator complex protein isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_004777 PE=4 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 9.899e-27
Identity = 53/129 (41.09%), Postives = 86/129 (66.67%), Query Frame = 1 
Query:   13 AVSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDH 399
            +  DHL+ FLS  DGI+GIF+ DKDGVV+   T+D+  DQ   P++  +F  ++QQ +K++LG  +++IT Y E VICQF+F    + P+   VVG++  ++G ++ALEP I  ++   +P ASS++ +
Sbjct:   88 SACDHLKRFLSEVDGILGIFVADKDGVVVASATMDDMPDQARSPYVTAAFIVSLQQVNKLDLGELEWMITSYQEMVICQFHFTCRLALPLFLTVVGSSECNIGAVIALEPSIRPLLNRLAPEASSRIQN 216
[Close]
BLAST of Ragulator complex protein isoform 1 vs. Ensembl Nematostella
Match: EDO46320 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ93])

HSP 1 Score: 55.0694 bits (131), Expect = 7.465e-10
Identity = 31/106 (29.25%), Postives = 55/106 (51.89%), Query Frame = 1 
Query:   22 DHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALE 339
            D +R F    DG++GI + D+DGV +VK          ++     +F  A +Q+SK+ L   K II  +  + +  FN+      P++  V+  + A+ G++L+LE
Sbjct:   11 DIMRRF----DGVLGIIVTDRDGVPVVKVADARIPGTALRSSYLATFATATEQASKLGLSKNKNIICTFPSYQVVHFNYL-----PLVVSVIATSQANTGVILSLE 107
[Close]
BLAST of Ragulator complex protein isoform 1 vs. Ensembl Medaka
Match: lamtor3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:NCBI gene;Acc:101169004])

HSP 1 Score: 51.6026 bits (122), Expect = 3.467e-8
Identity = 30/104 (28.85%), Postives = 53/104 (50.96%), Query Frame = 1 
Query:   52 DGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVE 363
            DG+  I + D+DGV ++K   D      ++P   ++F  A  Q SK+ L   K II  Y  + I QFN       P++   + ++ A+ G+++ LE  +  ++E
Sbjct:   25 DGLHAIVVTDRDGVPVIKVANDSVPVHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQIMQFN-----RLPLVVSFIASSSANTGLIMTLEKELAPLME 123
[Close]
BLAST of Ragulator complex protein isoform 1 vs. Planmine SMEST
Match: SMESG000058434.1 (SMESG000058434.1)

HSP 1 Score: 216.853 bits (551), Expect = 1.689e-72
Identity = 104/104 (100.00%), Postives = 104/104 (100.00%), Query Frame = 1 
Query:   97 MVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDHMKF 408
            MVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDHMKF
Sbjct:    1 MVKETLDENVDQFVQPHMQTSFTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNMADMGMMLALEPVILHVVEFFSPLASSKMDHMKF 104
The following BLAST results are available for this feature:
BLAST of Ragulator complex protein isoform 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
LAMTOR31.076e-727.68late endosomal/lysosomal adaptor, MAPK and MTOR ac... [more]
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG51101.652e-1132.41gene:FBgn0032642 transcript:FBtr0080983[more]
CG51101.652e-1132.41gene:FBgn0032642 transcript:FBtr0306162[more]
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|Q9VJD2|LTOR3_DROME1.656e-1032.41Ragulator complex protein LAMTOR3 homolog OS=Droso... [more]
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BLAST of Ragulator complex protein isoform 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2LA257.039e-2942.06Uncharacterized protein OS=Opisthorchis felineus O... [more]
Q86EA81.102e-2741.09Clone ZZD612 mRNA sequence OS=Schistosoma japonicu... [more]
A0A183QHU21.365e-2740.31Uncharacterized protein OS=Schistosoma rodhaini OX... [more]
G4LWW92.542e-2739.53Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4Z2D4329.899e-2741.09Ragulator complex protein isoform 1 OS=Schistosoma... [more]
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO463207.465e-1029.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ragulator complex protein isoform 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lamtor33.467e-828.85late endosomal/lysosomal adaptor, MAPK and MTOR ac... [more]
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BLAST of Ragulator complex protein isoform 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000058434.11.689e-72100.00SMESG000058434.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011568 ID=SMED30011568|Name=Ragulator complex protein isoform 1|organism=Schmidtea mediterranea sexual|type=transcript|length=738bp
TAAAATTGAATGGCTGTATCAGATCATTTACGAAATTTTCTCTCTCTTTC
CGACGGAATTATTGGGATATTTTTATGTGACAAAGATGGAGTCGTAATGG
TAAAAGAAACATTGGATGAAAATGTTGATCAATTTGTCCAACCTCATATG
CAGACTTCCTTTACGAATGCAATTCAGCAATCTTCAAAAATGAATTTAGG
CAACACCAAATATATTATTACCAGATATACAGAGTTTGTGATTTGTCAAT
TTAACTTCGCCAGAGATCCTAGTAAACCGATAATTGCAGTGGTAGTTGGA
AACAATATGGCAGATATGGGGATGATGCTGGCGTTGGAACCTGTGATTTT
GCATGTGGTGGAATTCTTCAGTCCTCTCGCATCCAGCAAAATGGATCACA
TGAAATTTTAAGCTCTGCACTATTATCATATACAATCAATAAAATTATCT
TTGTGTTTTTTATTTTTAATCGATTCAAGAATGATGCTGTAATTTTGTCG
AATTTATTTTGTTTTCTAATCATTTATAACACATTTGTTCACATTGAATT
TTTATTACTTCGGAATTGTTATTTTTATCACTTTCTAGCACTCATTTTTT
AGTAAGGCGCAATAAATGCTTATTTTAAAAGGTAACATCAACTAAGGATG
TCTCCTAAGAAGGGGAGGGAAGGGGGACTTCACAAAAGGGATAAATTGGG
ACACTTGGAAGGGGTATCAAGTACTTAGGACATCCCCA
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protein sequence of SMED30011568-orf-1

>SMED30011568-orf-1 ID=SMED30011568-orf-1|Name=SMED30011568-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=134bp
MAVSDHLRNFLSLSDGIIGIFLCDKDGVVMVKETLDENVDQFVQPHMQTS
FTNAIQQSSKMNLGNTKYIITRYTEFVICQFNFARDPSKPIIAVVVGNNM
ADMGMMLALEPVILHVVEFFSPLASSKMDHMKF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR015019LAMTOR3
Vocabulary: biological process
TermDefinition
GO:0032006regulation of TOR signaling
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015019Ragulator complex protein LAMTOR3SMARTSM01278MAPKK1_Int_3coord: 4..126
e-value: 2.7E-17
score: 73.4
IPR015019Ragulator complex protein LAMTOR3PFAMPF08923MAPKK1_Intcoord: 2..116
e-value: 1.9E-26
score: 92.2
IPR015019Ragulator complex protein LAMTOR3PANTHERPTHR13378REGULATOR COMPLEX PROTEIN LAMTOR3coord: 3..118
NoneNo IPR availableGENE3DG3DSA:3.30.450.30coord: 1..123
e-value: 1.9E-28
score: 100.6
NoneNo IPR availableSUPERFAMILYSSF103196Roadblock/LC7 domaincoord: 2..110