Ras associated and pleckstrin y

Overview


Name	Ras associated and pleckstrin y
Smed ID	SMED30011564
Length (bp)	1660

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ras associated and pleckstrin y (SMED30011564) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras associated and pleckstrin y (SMED30011564) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras associated and pleckstrin y (SMED30011564) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras associated and pleckstrin y (SMED30011564) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30011564

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30011564	h1SMcG0013831	dd_Smed_v4_17910_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30011564	h1SMcG0013831	dd_Smed_v4_17910_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30011564	h1SMcG0013831	Contig25052	newmark_ests	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30011564	h1SMcG0013831	dd_Smed_v4_26418_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30011564	h1SMcG0013831	dd_Smed_v4_26418_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30011564	h1SMcG0013831	dd_Smed_v4_26418_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30011564	h1SMcG0013831	dd_Smed_v4_26418_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
Match: GRB10 (growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564])

HSP 1 Score: 60.4622 bits (145), Expect = 1.279e-17
Identity = 37/113 (32.74%), Postives = 58/113 (51.33%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            +K+ +K ++CLR SG+Y   K    +   LQL+  L  S ++++ I G  Q  APT +G C+K    +N  K +   CA  E +   W + FR+   G  L+ NY+   Q  A
Sbjct:  298 KKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDS-NIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKA 409

HSP 2 Score: 49.6766 bits (117), Expect = 1.279e-17
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1

Query:  640 IARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLG---------SNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            + R   E Q     SLP I +   E C        +  +L    +  K  + V+  + T K + I    TA ++CQLL  +++ +    ++LVE   HL +ER  ED E   L +       ++S   F     KY  F +P  +           SN S+ +  + ++N          P  +  L  ++L +K+WK+
Sbjct:  114 VRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHE---LVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS------SSCPEIQGFLHVKELGKKSWKK 303

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
Match: GRB10 (growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564])

HSP 1 Score: 60.8474 bits (146), Expect = 1.486e-17
Identity = 37/113 (32.74%), Postives = 58/113 (51.33%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            +K+ +K ++CLR SG+Y   K    +   LQL+  L  S ++++ I G  Q  APT +G C+K    +N  K +   CA  E +   W + FR+   G  L+ NY+   Q  A
Sbjct:  246 KKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDS-NIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKA 357

HSP 2 Score: 49.2914 bits (116), Expect = 1.486e-17
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1

Query:  640 IARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLG---------SNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            + R   E Q     SLP I +   E C        +  +L    +  K  + V+  + T K + I    TA ++CQLL  +++ +    ++LVE   HL +ER  ED E   L +       ++S   F     KY  F +P  +           SN S+ +  + ++N          P  +  L  ++L +K+WK+
Sbjct:   62 VRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHE---LVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS------SSCPEIQGFLHVKELGKKSWKK 251

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
Match: GRB10 (growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564])

HSP 1 Score: 60.8474 bits (146), Expect = 1.486e-17
Identity = 37/113 (32.74%), Postives = 58/113 (51.33%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            +K+ +K ++CLR SG+Y   K    +   LQL+  L  S ++++ I G  Q  APT +G C+K    +N  K +   CA  E +   W + FR+   G  L+ NY+   Q  A
Sbjct:  246 KKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDS-NIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKA 357

HSP 2 Score: 49.2914 bits (116), Expect = 1.486e-17
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1

Query:  640 IARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLG---------SNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            + R   E Q     SLP I +   E C        +  +L    +  K  + V+  + T K + I    TA ++CQLL  +++ +    ++LVE   HL +ER  ED E   L +       ++S   F     KY  F +P  +           SN S+ +  + ++N          P  +  L  ++L +K+WK+
Sbjct:   62 VRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHE---LVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS------SSCPEIQGFLHVKELGKKSWKK 251

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
Match: GRB10 (growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564])

HSP 1 Score: 60.8474 bits (146), Expect = 1.486e-17
Identity = 37/113 (32.74%), Postives = 58/113 (51.33%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            +K+ +K ++CLR SG+Y   K    +   LQL+  L  S ++++ I G  Q  APT +G C+K    +N  K +   CA  E +   W + FR+   G  L+ NY+   Q  A
Sbjct:  246 KKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDS-NIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKA 357

HSP 2 Score: 49.2914 bits (116), Expect = 1.486e-17
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1

Query:  640 IARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLG---------SNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            + R   E Q     SLP I +   E C        +  +L    +  K  + V+  + T K + I    TA ++CQLL  +++ +    ++LVE   HL +ER  ED E   L +       ++S   F     KY  F +P  +           SN S+ +  + ++N          P  +  L  ++L +K+WK+
Sbjct:   62 VRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHE---LVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS------SSCPEIQGFLHVKELGKKSWKK 251

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
Match: GRB10 (growth factor receptor bound protein 10 [Source:HGNC Symbol;Acc:HGNC:4564])

HSP 1 Score: 60.8474 bits (146), Expect = 1.486e-17
Identity = 37/113 (32.74%), Postives = 58/113 (51.33%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            +K+ +K ++CLR SG+Y   K    +   LQL+  L  S ++++ I G  Q  APT +G C+K    +N  K +   CA  E +   W + FR+   G  L+ NY+   Q  A
Sbjct:  246 KKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDS-NIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKA 357

HSP 2 Score: 49.2914 bits (116), Expect = 1.486e-17
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1

Query:  640 IARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLG---------SNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            + R   E Q     SLP I +   E C        +  +L    +  K  + V+  + T K + I    TA ++CQLL  +++ +    ++LVE   HL +ER  ED E   L +       ++S   F     KY  F +P  +           SN S+ +  + ++N          P  +  L  ++L +K+WK+
Sbjct:   62 VRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHE---LVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS------SSCPEIQGFLHVKELGKKSWKK 251

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Celegans
Match: mig-10 (Abnormal cell migration protein 10 [Source:UniProtKB/Swiss-Prot;Acc:P34400])

HSP 1 Score: 66.2402 bits (160), Expect = 3.785e-11
Identity = 41/117 (35.04%), Postives = 60/117 (51.28%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ--NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTL 1535
            +K+ +K +  LR SG+Y   KS K    DL  +++LH S  +YT IG   + K+PTP+   +K    Q    ++I Y CA  E + + W    RIA  G  L  NY+   Q   +TL
Sbjct:  341 RKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLH-SNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETL 456

[Close]

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ--NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTL 1535
            +K+ +K +  LR SG+Y   KS K    DL  +++LH S  +YT IG   + K+PTP+   +K    Q    ++I Y CA  E + + W    RIA  G  L  NY+   Q   +TL
Sbjct:  341 RKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLH-SNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETL 456

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Celegans
Match: mig-10 (Abnormal cell migration protein 10 [Source:UniProtKB/Swiss-Prot;Acc:P34400])

HSP 1 Score: 65.855 bits (159), Expect = 4.233e-11
Identity = 41/117 (35.04%), Postives = 60/117 (51.28%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ--NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTL 1535
            +K+ +K +  LR SG+Y   KS K    DL  +++LH S  +YT IG   + K+PTP+   +K    Q    ++I Y CA  E + + W    RIA  G  L  NY+   Q   +TL
Sbjct:  358 RKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLH-SNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETL 473

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Celegans
Match: mig-10 (Abnormal cell migration protein 10 [Source:UniProtKB/Swiss-Prot;Acc:P34400])

HSP 1 Score: 65.855 bits (159), Expect = 4.233e-11
Identity = 41/117 (35.04%), Postives = 60/117 (51.28%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ--NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTL 1535
            +K+ +K +  LR SG+Y   KS K    DL  +++LH S  +YT IG   + K+PTP+   +K    Q    ++I Y CA  E + + W    RIA  G  L  NY+   Q   +TL
Sbjct:  358 RKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLH-SNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETL 473

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Celegans
Match: mig-10 (Abnormal cell migration protein 10 [Source:UniProtKB/Swiss-Prot;Acc:P34400])

HSP 1 Score: 65.855 bits (159), Expect = 4.233e-11
Identity = 41/117 (35.04%), Postives = 60/117 (51.28%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ--NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTL 1535
            +K+ +K +  LR SG+Y   KS K    DL  +++LH S  +YT IG   + K+PTP+   +K    Q    ++I Y CA  E + + W    RIA  G  L  NY+   Q   +TL
Sbjct:  358 RKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLH-SNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETL 473

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Fly
Match: pico (gene:FBgn0261811 transcript:FBtr0074804)

HSP 1 Score: 60.077 bits (144), Expect = 8.772e-17
Identity = 44/137 (32.12%), Postives = 71/137 (51.82%), Query Frame = 1

Query:  820 KTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSY-PDGGNKSMVFFEDREDKYGLFTD-----PGKWLGSNFSENEKER-YYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            K++L+DE    G + +LL  +N++     ++LVE    L++ER+FED E  V  L+++  D GN+  V F+ R DK  LF       PG  +      +E+ R   ++E FD    QL +    L+ +   +K WKR
Sbjct:  380 KSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNR--VLFQQRPDKVTLFLRPELYLPGPQMAPGCQHDEQTRQMLLDEFFDS-HNQL-QMDGPLYMKADPKKGWKR 512

HSP 2 Score: 46.595 bits (109), Expect = 8.772e-17
Identity = 28/113 (24.78%), Postives = 56/113 (49.56%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGE----QNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K  ++    LR+SG+Y + K    +  DL  +   H   ++YT +G   + K+PT Y F  K  G+    ++ + +   CA    +L  W +  R+   GK L+ ++++ ++
Sbjct:  507 KKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFHGH-NVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLE 618

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Fly
Match: pico (gene:FBgn0261811 transcript:FBtr0303995)

HSP 1 Score: 60.077 bits (144), Expect = 1.026e-16
Identity = 44/137 (32.12%), Postives = 71/137 (51.82%), Query Frame = 1

Query:  820 KTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSY-PDGGNKSMVFFEDREDKYGLFTD-----PGKWLGSNFSENEKER-YYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            K++L+DE    G + +LL  +N++     ++LVE    L++ER+FED E  V  L+++  D GN+  V F+ R DK  LF       PG  +      +E+ R   ++E FD    QL +    L+ +   +K WKR
Sbjct:  331 KSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNR--VLFQQRPDKVTLFLRPELYLPGPQMAPGCQHDEQTRQMLLDEFFDS-HNQL-QMDGPLYMKADPKKGWKR 463

HSP 2 Score: 46.2098 bits (108), Expect = 1.026e-16
Identity = 28/113 (24.78%), Postives = 56/113 (49.56%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGE----QNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K  ++    LR+SG+Y + K    +  DL  +   H   ++YT +G   + K+PT Y F  K  G+    ++ + +   CA    +L  W +  R+   GK L+ ++++ ++
Sbjct:  458 KKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFHGH-NVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLE 569

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Fly
Match: pico (gene:FBgn0261811 transcript:FBtr0074805)

HSP 1 Score: 60.4622 bits (145), Expect = 2.017e-15
Identity = 44/137 (32.12%), Postives = 71/137 (51.82%), Query Frame = 1

Query:  820 KTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSY-PDGGNKSMVFFEDREDKYGLFTD-----PGKWLGSNFSENEKER-YYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            K++L+DE    G + +LL  +N++     ++LVE    L++ER+FED E  V  L+++  D GN+  V F+ R DK  LF       PG  +      +E+ R   ++E FD    QL +    L+ +   +K WKR
Sbjct:  252 KSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNR--VLFQQRPDKVTLFLRPELYLPGPQMAPGCQHDEQTRQMLLDEFFDS-HNQL-QMDGPLYMKADPKKGWKR 384

HSP 2 Score: 41.5874 bits (96), Expect = 2.017e-15
Identity = 28/113 (24.78%), Postives = 56/113 (49.56%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGE----QNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K  ++    LR+SG+Y + K    +  DL  +   H   ++YT +G   + K+PT Y F  K  G+    ++ + +   CA    +L  W +  R+   GK L+ ++++ ++
Sbjct:  379 KKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFH-GHNVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLE 490

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Fly
Match: pico (gene:FBgn0261811 transcript:FBtr0303996)

HSP 1 Score: 60.4622 bits (145), Expect = 2.017e-15
Identity = 44/137 (32.12%), Postives = 71/137 (51.82%), Query Frame = 1

Query:  820 KTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSY-PDGGNKSMVFFEDREDKYGLFTD-----PGKWLGSNFSENEKER-YYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            K++L+DE    G + +LL  +N++     ++LVE    L++ER+FED E  V  L+++  D GN+  V F+ R DK  LF       PG  +      +E+ R   ++E FD    QL +    L+ +   +K WKR
Sbjct:  252 KSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNR--VLFQQRPDKVTLFLRPELYLPGPQMAPGCQHDEQTRQMLLDEFFDS-HNQL-QMDGPLYMKADPKKGWKR 384

HSP 2 Score: 41.5874 bits (96), Expect = 2.017e-15
Identity = 28/113 (24.78%), Postives = 56/113 (49.56%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGE----QNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K  ++    LR+SG+Y + K    +  DL  +   H   ++YT +G   + K+PT Y F  K  G+    ++ + +   CA    +L  W +  R+   GK L+ ++++ ++
Sbjct:  379 KKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFH-GHNVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLE 490

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Zebrafish
Match: grb7 (growth factor receptor bound protein 7 [Source:ZFIN;Acc:ZDB-GENE-091118-23])

HSP 1 Score: 48.9062 bits (115), Expect = 8.512e-12
Identity = 33/106 (31.13%), Postives = 50/106 (47.17%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ-NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQ 1505
            +K+ +K +  LR SG+Y   K    +   LQ    L   L+++T   G     AP  + FC+K+  E+   + +   CA SE S   W + FR+   G  L  NYQ
Sbjct:  244 KKSWKKLYFVLRRSGLYCSSKGQSKEPRHLQFTGDLE-DLNVFTVFTGRKHYGAPGEHVFCIKSSKERFRGQDLKLMCADSEQSRTCWITAFRLFKHGTQLQQNYQ 348

HSP 2 Score: 41.2022 bits (95), Expect = 8.512e-12
Identity = 32/156 (20.51%), Postives = 67/156 (42.95%), Query Frame = 1

Query:  766 PTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNFSENEKE--------RYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            P+      + V+      +++L+    TA ++CQ+L    +      ++L+E  + L +ER  ED E  +    S+P  G+  ++F ++   KY  F  P  +   +   +  +            N +  G  P++  +   L  R+  +K+WK+
Sbjct:   98 PSDSSTHVVRVFSDATHCRSVLVSSRATAHDVCQMLAQSAHCTDEESWALIEHHTALGLERCLEDHELVLQVQSSWPVEGDTKLLFRKNYA-KYEFFKKPVSFFPEHMISDSADVTKGMTSSELVQNMVKSGSCPEIQGF---LHVREGGKKSWKK 249

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Zebrafish
Match: wu:fj59g11 (wu:fj59g11 [Source:ZFIN;Acc:ZDB-GENE-030131-8202])

HSP 1 Score: 65.0846 bits (157), Expect = 1.412e-10
Identity = 47/165 (28.48%), Postives = 83/165 (50.30%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  + L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L         ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  349 KLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIE-RIEKYALFKNPQNYLLGRKETCEMADRNKE-ALLEECFGGSTISVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 504

HSP 2 Score: 51.9878 bits (123), Expect = 1.435e-6
Identity = 39/125 (31.20%), Postives = 58/125 (46.40%), Query Frame = 3

Query: 1146 SIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            S+  ++    L    +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C      L  W +  RIA  GK L+VNYQ  ++
Sbjct:  474 SVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQL-DHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMR 597

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Zebrafish
Match: grb10a (growth factor receptor-bound protein 10a [Source:ZFIN;Acc:ZDB-GENE-040822-32])

HSP 1 Score: 59.3066 bits (142), Expect = 7.514e-9
Identity = 45/135 (33.33%), Postives = 67/135 (49.63%), Query Frame = 3

Query: 1143 SSIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSF 1544
            SS   +Q    + +T +K+ +K +M LR SG+Y   K    +   LQL+  L  S +++T   G     APT Y FC+K + G    K +   CA  E S   W + FR+   G  L+ NY+T  Q    T+S+F
Sbjct:  297 SSCPEIQGFLYMKETGRKSWKKLYMFLRRSGLYYSTKGMSKEPRHLQLLSDLEES-NIFTVTTGRKMHNAPTDYQFCIKPSKGRTELKELKMLCAEDEQSRTCWMTAFRLLKFGILLYQNYKTPHQ--RKTISNF 428

[Close]

Query: 1143 SSIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSF 1544
            SS   +Q    + +T +K+ +K +M LR SG+Y   K    +   LQL+  L  S +++T   G     APT Y FC+K + G    K +   CA  E S   W + FR+   G  L+ NY+T  Q    T+S+F
Sbjct:  297 SSCPEIQGFLYMKETGRKSWKKLYMFLRRSGLYYSTKGMSKEPRHLQLLSDLEES-NIFTVTTGRKMHNAPTDYQFCIKPSKGRTELKELKMLCAEDEQSRTCWMTAFRLLKFGILLYQNYKTPHQ--RKTISNF 428

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Zebrafish
Match: raph1b (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b [Source:ZFIN;Acc:ZDB-GENE-090311-54])

HSP 1 Score: 59.3066 bits (142), Expect = 1.088e-8
Identity = 47/165 (28.48%), Postives = 83/165 (50.30%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++      ++LVE    L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L      S  ++  KE   + E F G    +P  +  L+ ++  +K+WK+       R F+L  S I
Sbjct:  287 KLVIRVHMSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSPDWALVETIPELQMERIFEDHENLVENLLNWTRDSQNKLMFIE-RIEKYALFKNPQNYLLGRKETSEMADRNKE-ALLEECFCGSSVSVPEIEGVLWLKEDGKKSWKK-------RYFLLRASGI 442

HSP 2 Score: 54.299 bits (129), Expect = 3.548e-7
Identity = 38/125 (30.40%), Postives = 60/125 (48.00%), Query Frame = 3

Query: 1146 SIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            S+  ++    L +  +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L++NYQ  ++
Sbjct:  412 SVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEAMK 535

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
Match: nr1d2 (nuclear receptor subfamily 1 group D member 2 [Source:Xenbase;Acc:XB-GENE-478410])

HSP 1 Score: 54.299 bits (129), Expect = 6.450e-17
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL 1077
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L
Sbjct:  313 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVE-RIEKYALFKNPQNYL 410

HSP 2 Score: 53.5286 bits (127), Expect = 6.450e-17
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  442 KKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGLRIAKYGKQLYTNYQEALK 550

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
Match: nr1d2 (nuclear receptor subfamily 1 group D member 2 [Source:Xenbase;Acc:XB-GENE-478410])

HSP 1 Score: 57.3806 bits (137), Expect = 8.479e-17
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL 1077
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L
Sbjct:  314 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVE-RIEKYALFKNPQNYL 411

HSP 2 Score: 50.0618 bits (118), Expect = 8.479e-17
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  443 KKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGLRIAKYGKQLYTNYQEALK 551

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
Match: nr1d2 (nuclear receptor subfamily 1 group D member 2 [Source:Xenbase;Acc:XB-GENE-478410])

HSP 1 Score: 54.6842 bits (130), Expect = 1.939e-15
Identity = 39/124 (31.45%), Postives = 66/124 (53.23%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDG 1137
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L      S  ++  KE   + E F G
Sbjct:  297 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVE-RIEKYALFKNPQNYLLGRKETSEMADRNKE-VLLEECFCG 418

HSP 2 Score: 48.521 bits (114), Expect = 1.939e-15
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  426 KKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGLRIAKYGKQLYTNYQEALK 534

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
Match: nr1d2 (nuclear receptor subfamily 1 group D member 2 [Source:Xenbase;Acc:XB-GENE-478410])

HSP 1 Score: 54.299 bits (129), Expect = 2.942e-15
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL 1077
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L
Sbjct:  272 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVE-RIEKYALFKNPQNYL 369

HSP 2 Score: 48.1358 bits (113), Expect = 2.942e-15
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  401 KKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGLRIAKYGKQLYTNYQEALK 509

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
Match: rock1 (Rho-associated, coiled-coil containing protein kinase 1 [Source:Xenbase;Acc:XB-GENE-984661])

HSP 1 Score: 58.9214 bits (141), Expect = 1.159e-8
Identity = 37/109 (33.94%), Postives = 56/109 (51.38%), Query Frame = 3

Query: 1182 KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQ 1505
            +  +K+ +K F+CLR SG+Y   K    +   LQ I  L  S ++Y+ I       APT +GFC+K    +N  K + + CA  E S   W + FR+   G  L+ NY+
Sbjct:  138 EVGKKSWKKLFVCLRRSGLYCSTKGMSKEPRHLQGISDLEDS-NIYSLISCKKLYNAPTDFGFCVKPNKVRNEVKELRFLCAEDEQSRTCWMTAFRLLKYGMLLYQNYR 245

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
Match: Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:MGI Symbol;Acc:MGI:1924550])

HSP 1 Score: 68.5514 bits (166), Expect = 1.089e-11
Identity = 49/165 (29.70%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDP-----GKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P     GK   +  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  323 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFME-RIEKYALFKNPQNYLLGKKETAEMADRNKE-VLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 478

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
Match: Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:MGI Symbol;Acc:MGI:1924550])

HSP 1 Score: 67.781 bits (164), Expect = 2.161e-11
Identity = 49/165 (29.70%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDP-----GKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P     GK   +  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  323 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFME-RIEKYALFKNPQNYLLGKKETAEMADRNKE-VLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 478

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
Match: Grb14 (growth factor receptor bound protein 14 [Source:MGI Symbol;Acc:MGI:1355324])

HSP 1 Score: 64.6994 bits (156), Expect = 1.544e-10
Identity = 36/104 (34.62%), Postives = 51/104 (49.04%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNY 1502
            +K+ +K +  LR SG+Y   K    +   LQL      S H+Y ++ G  +  APTPYGFCLK      P+ +   CA  E S   W +  R+   G  L+ NY
Sbjct:  246 KKSWKKAYFFLRRSGLYFSTKGTSKEPRHLQLFSEFSTS-HVYMSLAGKKKHGAPTPYGFCLKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKDGMQLYQNY 348

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
Match: Raph1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:MGI Symbol;Acc:MGI:1924550])

HSP 1 Score: 63.1586 bits (152), Expect = 8.350e-10
Identity = 49/165 (29.70%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDP-----GKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P     GK   +  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  271 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFME-RIEKYALFKNPQNYLLGKKETAEMADRNKE-VLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 426

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
Match: Apbb1ip (amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Source:MGI Symbol;Acc:MGI:1861354])

HSP 1 Score: 53.5286 bits (127), Expect = 5.498e-7
Identity = 38/123 (30.89%), Postives = 58/123 (47.15%), Query Frame = 3

Query: 1149 IATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQI 1514
            +  L+    L +  +K+ ++ +  LR SGIY   K       DL   I    ++++Y  I    + KAPT + F LK    ++  +YI Y C     +L  W    RIA  GKTL+ NYQ  +
Sbjct:  313 VPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFE-NVNIYYGIQCKMKYKAPTDHCFVLKHPQIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYDNYQRAV 434

HSP 2 Score: 51.9878 bits (123), Expect = 1.693e-6
Identity = 49/180 (27.22%), Postives = 85/180 (47.22%), Query Frame = 1

Query:  808 NRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDP------GKWLGSNFSENEK-----ERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI----KMTLQTCS*LSVFI 1302
            + + K++++DE   A ++   L  + +    + + L E    L+IER+FED E  V+ +LS      ++ V F ++E++Y +F +P       K    N   NEK     + Y + E F G    +P  +  L+ ++  +K+WKR       R F+L  S I    K   +T   L+ FI
Sbjct:  189 DSSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERVFEDHEN-VVEVLSDWTRDTENKVLFLEKEERYAVFKNPQNFYLDNKGKKENKETNEKMNAKNKEYLLEESFCGTSIIVPELEGALYLKEDGKKSWKR-------RYFLLRASGIYYVPKGKTKTSRDLACFI 360

[Close]

BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
Match: sp|P34400|MIG10_CAEEL (Abnormal cell migration protein 10 OS=Caenorhabditis elegans OX=6239 GN=mig-10 PE=1 SV=3)

HSP 1 Score: 65.855 bits (159), Expect = 6.336e-10
Identity = 41/117 (35.04%), Postives = 60/117 (51.28%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQ--NPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTL 1535
            +K+ +K +  LR SG+Y   KS K    DL  +++LH S  +YT IG   + K+PTP+   +K    Q    ++I Y CA  E + + W    RIA  G  L  NY+   Q   +TL
Sbjct:  470 RKSWKKHYFVLRPSGLYYAPKSKKPTTKDLTCLMNLH-SNQVYTGIGWEKKYKSPTPWCISIKLTALQMKRSQFIKYICAEDEMTFKKWLVALRIAKNGAELLENYERACQIRRETL 585

[Close]

BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
Match: sp|Q9JLM9|GRB14_MOUSE (Growth factor receptor-bound protein 14 OS=Mus musculus OX=10090 GN=Grb14 PE=1 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.080e-9
Identity = 36/104 (34.62%), Postives = 51/104 (49.04%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNY 1502
            +K+ +K +  LR SG+Y   K    +   LQL      S H+Y ++ G  +  APTPYGFCLK      P+ +   CA  E S   W +  R+   G  L+ NY
Sbjct:  246 KKSWKKAYFFLRRSGLYFSTKGTSKEPRHLQLFSEFSTS-HVYMSLAGKKKHGAPTPYGFCLKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKDGMQLYQNY 348

[Close]

BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
Match: sp|Q70E73|RAPH1_HUMAN (Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=RAPH1 PE=1 SV=3)

HSP 1 Score: 63.5438 bits (153), Expect = 3.692e-9
Identity = 49/165 (29.70%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDP-----GKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P     GK   +  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  270 KLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFME-RIEKYALFKNPQNYLLGKKETAEMADRNKE-VLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 425

[Close]

BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
Match: sp|B5KFD7|GRB10_PIG (Growth factor receptor-bound protein 10 OS=Sus scrofa OX=9823 GN=Grb10 PE=2 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 4.354e-9
Identity = 45/135 (33.33%), Postives = 65/135 (48.15%), Query Frame = 3

Query: 1143 SSIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSF 1544
            SS   +Q    + +  +K+ +K ++CLR SG+Y   K    +   LQL+  L  S  +++ I G  Q  APT YGFC+K        K +   CA  E S   W + FR+   G  L+ NY+   Q  A  LS F
Sbjct:  283 SSCPEIQGFLHVKELGRKSWKKLYVCLRRSGLYCSTKGASKEPRHLQLLADLEDS-SIFSLIAGRKQYGAPTDYGFCIKPNRVRTEAKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYRVPQQRKA-VLSPF 415

HSP 2 Score: 53.1434 bits (126), Expect = 4.913e-6
Identity = 53/199 (26.63%), Postives = 84/199 (42.21%), Query Frame = 1

Query:  646 RFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDE--TPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLG---------SNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            R   E Q     SLP I +   E C        S  +L    +  K  + V+  + T K + I    TA ++CQLL  R++ +    ++LVE   HL +ER  ED E  T V + L+     ++S   F     KY  F +P  +           SN S+ +  + ++N          P  +  L  ++L RK+WK+
Sbjct:  117 RLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLSPGSLPPGQAAAKQDVKVFSEDGTCKVVEILADMTARDLCQLLVYRSHCVDDNSWTLVEHHPHLGLERGLEDHERVTQVQHTLA-----SESKFLFRKNYAKYEFFKNPTNFFPEQMVTWCQQSNGSQTQLLQNFLNSS------SCPEIQGFLHVKELGRKSWKK 304

[Close]

BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
Match: sp|Q13322|GRB10_HUMAN (Growth factor receptor-bound protein 10 OS=Homo sapiens OX=9606 GN=GRB10 PE=1 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 2.301e-8
Identity = 43/135 (31.85%), Postives = 67/135 (49.63%), Query Frame = 3

Query: 1143 SSIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNP-KYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSF 1544
            SS   +Q    + +  +K+ +K ++CLR SG+Y   K    +   LQL+  L  S ++++ I G  Q  APT +G C+K    +N  K +   CA  E +   W + FR+   G  L+ NY+   Q  A  LS F
Sbjct:  288 SSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDS-NIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKA-LLSPF 420

[Close]

BLAST of Ras associated and pleckstrin y vs. TrEMBL
Match: A0A068YJN4 (Growth factor receptor bound protein OS=Echinococcus multilocularis OX=6211 GN=EmuJ_001010600 PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 6.977e-41
Identity = 61/152 (40.13%), Postives = 90/152 (59.21%), Query Frame = 1

Query:  775 DYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNF---SENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            D K+ L V+QPNRT K I +   T AGE+  +L A+N+L    K +LVEK   +K+ER FEDDE     +LS+P   +++++FFE+R+D +GLF DP  WLG+     S   K    I+ +      +LP +K +L+  + + K WKR  CV
Sbjct:  309 DKKVILRVHQPNRTTKAIYVQSRTDAGEVVLMLAAKNFLPLSTKMALVEKVPSMKLERCFEDDEPVRDCILSWPV-NSENLIFFEERQDLFGLFEDPQTWLGNTLVGESAQTKNSLLIDILEKDGANRLPPFKDYLYILQPNNK-WKRRYCV 458

HSP 2 Score: 92.8189 bits (229), Expect = 6.977e-41
Identity = 46/110 (41.82%), Postives = 65/110 (59.09%), Query Frame = 3

Query: 1203 EKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG--EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            ++ +  LR+SG+YA KK   +D ++L  + +    LHLYTT GGW +  APTPYGF LK +     +P  +  FCA +E SLR W S+ RI L G  L  NY+ ++   A
Sbjct:  453 KRRYCVLRSSGLYASKKQG-SDISELVRVTAFGEHLHLYTTSGGWRKANAPTPYGFVLKPHSVVTMDPHMVRAFCAANEESLRIWCSLLRIILMGPRLLQNYRQRLAACA 561

[Close]

BLAST of Ras associated and pleckstrin y vs. TrEMBL
Match: A0A068WG15 (Growth factor receptor bound protein OS=Echinococcus granulosus OX=6210 GN=EgrG_001010600 PE=4 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 3.709e-40
Identity = 60/152 (39.47%), Postives = 90/152 (59.21%), Query Frame = 1

Query:  775 DYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNF---SENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            D K+ L V+QP+RT K I +   T AGE+  +L A+N+L    K +LVEK   +K+ER FEDDE     +LS+P   +++++FFE+R+D +GLF DP  WLG+     S   K    I+ +      +LP +K +L+  + + K WKR  CV
Sbjct:  309 DKKVILRVHQPDRTTKAIYVQSRTDAGEVVLMLAAKNFLPLSTKMALVEKVPSMKLERCFEDDEPVRDCILSWPV-NSENLIFFEERQDLFGLFEDPQTWLGNTLVGESAQMKNSLLIDILEKDGANRLPPFKDYLYILQPNNK-WKRRYCV 458

HSP 2 Score: 92.8189 bits (229), Expect = 3.709e-40
Identity = 46/110 (41.82%), Postives = 65/110 (59.09%), Query Frame = 3

Query: 1203 EKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG--EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            ++ +  LR+SG+YA KK   +D ++L  + +    LHLYTT GGW +  APTPYGF LK +     +P  +  FCA +E SLR W S+ RI L G  L  NY+ ++   A
Sbjct:  453 KRRYCVLRSSGLYASKKQG-SDISELVRVTAFGEHLHLYTTSGGWRKANAPTPYGFVLKPHSVVTMDPHMVRAFCAANEESLRIWCSLLRIILMGPRLLQNYRQRLAACA 561

[Close]

BLAST of Ras associated and pleckstrin y vs. TrEMBL
Match: A0A564YP35 (Ras-associating domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8000 PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 1.170e-38
Identity = 58/152 (38.16%), Postives = 90/152 (59.21%), Query Frame = 1

Query:  775 DYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNF---SENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            D K+ L ++QP+RT K + +   T AGE+  +L A+N+L    K +LVEK   +K+ER FEDDE     +LS+P   N++++FFE+R+D +G+F DP  WLG+     S   K    I+ +      +LP +K +L+  + + K WKR  CV
Sbjct:  112 DKKVVLRIHQPDRTTKAVYVQSRTDAGEVVLMLAAKNFLPLSTKMALVEKVPSMKLERCFEDDEVVRDCVLSWPV-SNENLIFFEERQDLFGIFEDPQTWLGNTLIGDSAQMKNSLLIDILEKDGANRLPPFKDYLYILRPNNK-WKRRYCV 261

HSP 2 Score: 85.5001 bits (210), Expect = 1.170e-38
Identity = 43/110 (39.09%), Postives = 62/110 (56.36%), Query Frame = 3

Query: 1203 EKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG--EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            ++ +  LR+SG+YA KK      ++L  + +    LHLYTT GGW +   PTPYGF LK +   + +P  +  FCA +E SLR W S+ RI L G  L   Y+ ++   A
Sbjct:  256 KRRYCVLRSSGLYASKKQGSG-ISELVRVTAFGEHLHLYTTSGGWKKDNTPTPYGFVLKPHSVVKMDPHMVRAFCAANEESLRIWCSLLRIILMGPRLLQTYRQRLAACA 364

[Close]

BLAST of Ras associated and pleckstrin y vs. TrEMBL
Match: A0A564YPY2 (Ras-associating domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8000 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 2.206e-38
Identity = 58/152 (38.16%), Postives = 90/152 (59.21%), Query Frame = 1

Query:  775 DYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNF---SENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            D K+ L ++QP+RT K + +   T AGE+  +L A+N+L    K +LVEK   +K+ER FEDDE     +LS+P   N++++FFE+R+D +G+F DP  WLG+     S   K    I+ +      +LP +K +L+  + + K WKR  CV
Sbjct:  315 DKKVVLRIHQPDRTTKAVYVQSRTDAGEVVLMLAAKNFLPLSTKMALVEKVPSMKLERCFEDDEVVRDCVLSWPV-SNENLIFFEERQDLFGIFEDPQTWLGNTLIGDSAQMKNSLLIDILEKDGANRLPPFKDYLYILRPNNK-WKRRYCV 464

HSP 2 Score: 85.1149 bits (209), Expect = 2.206e-38
Identity = 43/110 (39.09%), Postives = 62/110 (56.36%), Query Frame = 3

Query: 1203 EKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG--EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            ++ +  LR+SG+YA KK      ++L  + +    LHLYTT GGW +   PTPYGF LK +   + +P  +  FCA +E SLR W S+ RI L G  L   Y+ ++   A
Sbjct:  459 KRRYCVLRSSGLYASKKQGSG-ISELVRVTAFGEHLHLYTTSGGWKKDNTPTPYGFVLKPHSVVKMDPHMVRAFCAANEESLRIWCSLLRIILMGPRLLQTYRQRLAACA 567

[Close]

BLAST of Ras associated and pleckstrin y vs. TrEMBL
Match: W6URB4 (Ras-associated and pleckstriny domains-containing protein OS=Echinococcus granulosus OX=6210 GN=EGR_00814 PE=4 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 6.210e-37
Identity = 46/110 (41.82%), Postives = 65/110 (59.09%), Query Frame = 3

Query: 1203 EKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG--EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVA 1526
            ++ +  LR+SG+YA KK   +D ++L  + +    LHLYTT GGW +  APTPYGF LK +     +P  +  FCA +E SLR W S+ RI L G  L  NY+ ++   A
Sbjct:  426 KRRYCVLRSSGLYASKKQG-SDISELVRVTAFGEHLHLYTTSGGWRKANAPTPYGFVLKPHSVVTMDPHMVRAFCAANEESLRIWCSLLRIILMGPRLLQNYRQRLAACA 534

HSP 2 Score: 92.4337 bits (228), Expect = 6.210e-37
Identity = 57/152 (37.50%), Postives = 85/152 (55.92%), Query Frame = 1

Query:  775 DYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL---GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            D K+ L V+QP+RT K I +   T AGE+  +L A+N+L    K +LVEK   +K+ER FEDDE     +LS+P   +++++FFE+R+D +GLF DP   L   G+N                    +LP +K +L+  + + K WKR  CV
Sbjct:  302 DKKVILRVHQPDRTTKAIYVQSRTDAGEVVLMLAAKNFLPLSTKMALVEKVPSMKLERCFEDDEPVRDCILSWPV-NSENLIFFEERQDLFGLFEDPQDILEKDGAN--------------------RLPPFKDYLYILQPNNK-WKRRYCV 431

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
Match: wu:fj59g11 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:NCBI gene;Acc:103043657])

HSP 1 Score: 65.855 bits (159), Expect = 6.475e-11
Identity = 48/165 (29.09%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L         ++  KE   + E F G    +P  +  L+ ++  +K+WK+       R F+L  S I
Sbjct:  282 KLVIRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEMISELQMERIFEDHENLVENLLNWTRDSTNRLMFIE-RIEKYALFKNPQNYLLGRKETCEMTDRNKE-ALLEECFCGSSISVPEMEGVLWLKEDGKKSWKK-------RYFLLRASGI 437

HSP 2 Score: 54.299 bits (129), Expect = 2.742e-7
Identity = 39/125 (31.20%), Postives = 60/125 (48.00%), Query Frame = 3

Query: 1146 SIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            S+  ++    L +  +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+VNYQ  ++
Sbjct:  407 SVPEMEGVLWLKEDGKKSWKKRYFLLRASGIYYVPKGKPKASRDLVCFLQLD-HVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGVRIAKYGKQLYVNYQEAMK 530

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
Match: raph1b (ras-associated and pleckstrin homology domains-containing protein 1-like [Source:NCBI gene;Acc:103040117])

HSP 1 Score: 59.6918 bits (143), Expect = 7.406e-9
Identity = 46/165 (27.88%), Postives = 83/165 (50.30%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  +  ++   L  +++      ++LVE  + L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L      S  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  343 KLVIRVHMSDESSKTMMVDERQSVRQVLDSLLDKSHCGYSPDWALVETITELQMERIFEDHENLVENLLNWTRDSQNKLMFIE-RIEKYALFKNPQNYLLGRKETSEMADRNKEA-LLEECFCGGSVSVPEIEGILWLKDDGKKSWKK-------RYFLLRASGI 498

HSP 2 Score: 52.7582 bits (125), Expect = 8.712e-7
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  483 KKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYSNYQEAMK 591

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
Match: raph1b (ras-associated and pleckstrin homology domains-containing protein 1-like [Source:NCBI gene;Acc:103040117])

HSP 1 Score: 59.6918 bits (143), Expect = 7.443e-9
Identity = 46/165 (27.88%), Postives = 83/165 (50.30%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  +  ++   L  +++      ++LVE  + L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L      S  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  309 KLVIRVHMSDESSKTMMVDERQSVRQVLDSLLDKSHCGYSPDWALVETITELQMERIFEDHENLVENLLNWTRDSQNKLMFIE-RIEKYALFKNPQNYLLGRKETSEMADRNKEA-LLEECFCGGSVSVPEIEGILWLKDDGKKSWKK-------RYFLLRASGI 464

HSP 2 Score: 52.7582 bits (125), Expect = 8.685e-7
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  449 KKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYSNYQEAMK 557

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
Match: raph1b (ras-associated and pleckstrin homology domains-containing protein 1-like [Source:NCBI gene;Acc:103040117])

HSP 1 Score: 59.6918 bits (143), Expect = 7.861e-9
Identity = 46/165 (27.88%), Postives = 83/165 (50.30%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  +  ++   L  +++      ++LVE  + L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L      S  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  339 KLVIRVHMSDESSKTMMVDERQSVRQVLDSLLDKSHCGYSPDWALVETITELQMERIFEDHENLVENLLNWTRDSQNKLMFIE-RIEKYALFKNPQNYLLGRKETSEMADRNKEA-LLEECFCGGSVSVPEIEGILWLKDDGKKSWKK-------RYFLLRASGI 494

HSP 2 Score: 53.1434 bits (126), Expect = 8.635e-7
Identity = 36/110 (32.73%), Postives = 53/110 (48.18%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+ NYQ  ++
Sbjct:  479 KKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLD-HVNVYYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYSNYQEAMK 587

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
Match: wu:fj59g11 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Source:NCBI gene;Acc:103043657])

HSP 1 Score: 59.3066 bits (142), Expect = 8.025e-9
Identity = 48/165 (29.09%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++    + +SLVE  S L++ERIFED E  V  LL++       ++F E R +KY LF +P  +L         ++  KE   + E F G    +P  +  L+ ++  +K+WK+       R F+L  S I
Sbjct:  310 KLVIRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEMISELQMERIFEDHENLVENLLNWTRDSTNRLMFIE-RIEKYALFKNPQNYLLGRKETCEMTDRNKE-ALLEECFCGSSISVPEMEGVLWLKEDGKKSWKK-------RYFLLRASGI 465

HSP 2 Score: 55.4546 bits (132), Expect = 1.344e-7
Identity = 39/125 (31.20%), Postives = 60/125 (48.00%), Query Frame = 3

Query: 1146 SIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            S+  ++    L +  +K+ +K +  LR SGIY   K       DL   + L   +++Y      S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+VNYQ  ++
Sbjct:  435 SVPEMEGVLWLKEDGKKSWKKRYFLLRASGIYYVPKGKPKASRDLVCFLQLD-HVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGVRIAKYGKQLYVNYQEAMK 558

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Sea Lamprey
Match: wu:fj59g11 (wu:fj59g11 [Source:ZFIN;Acc:ZDB-GENE-030131-8202])

HSP 1 Score: 54.299 bits (129), Expect = 5.220e-8
Identity = 36/125 (28.80%), Postives = 60/125 (48.00%), Query Frame = 3

Query: 1146 SIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            ++  L+    L +  +K+ +K +  LR SGIY   K       DL   I     + +Y      ++ KAPT Y F LK    ++  +YI Y C    + L+ W +  R+A  G+T++ NYQ  ++
Sbjct:   72 TVPELEGVLYLKEDGKKSWKKRYFLLRASGIYYVPKGKTKTLRDLSCFIQFD-HVSVYYGQDFRTKYKAPTEYCFALKHPQIQKKSQYIKYLCCDDASGLQQWVTGIRVAKYGRTMYDNYQDALK 195

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Sea Lamprey
Match: apbb1ip (amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Source:NCBI gene;Acc:393607])

HSP 1 Score: 52.373 bits (124), Expect = 1.707e-7
Identity = 48/182 (26.37%), Postives = 86/182 (47.25%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKW-LGSNFSENEKER---YYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI----KMTLQTCS*LSVFI 1302
            K+ + +   +++ K ++++E  +  E+   L  + +      + LVE    L +ER +ED E  V  L+++       + F E RE K  LF +P  + LG+  +++ K+R     + E F G    +P  +  LF ++  +K+WKR       R F+L  S I    K   +T   L+ FI
Sbjct:   30 KLVIRIGLVDKSSKNLMVEEQQSVREVMDNLREKTHSTNSPDWCLVETNPDLDMERFYEDHENLVQNLVTWTRDTQNGLTFVERRE-KNALFKNPQNYLLGNKEAKDVKDRDKESLLEECFCGTSVAVPELEGELFLKEDGKKSWKR-------RYFLLRASGIYFVPKGKTKTLRDLTCFI 203

HSP 2 Score: 51.2174 bits (121), Expect = 4.501e-7
Identity = 36/121 (29.75%), Postives = 58/121 (47.93%), Query Frame = 3

Query: 1146 SIATLQITFIL*KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYG-EQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQ 1505
            ++  L+    L +  +K+ ++ +  LR SGIY   K       DL   I    +L++Y  +   ++ KAPT   F LK    ++  +YI Y C     SL  W +  RIA  GK L+ N++
Sbjct:  155 AVPELEGELFLKEDGKKSWKRRYFLLRASGIYFVPKGKTKTLRDLTCFIQFE-NLNVYYCLDYKNKYKAPTDCCFALKHPQIQKKSQYIKYLCCDDARSLHQWVTGIRIAKYGKYLYDNFK 274

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Nematostella
Match: EDO35745 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKL3])

HSP 1 Score: 60.8474 bits (146), Expect = 4.137e-10
Identity = 50/152 (32.89%), Postives = 76/152 (50.00%), Query Frame = 1

Query:  781 KMPLTVYQ-PNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL--------GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKR 1209
            K+ + VY   + T KTI ID+T T+ E+C+ +  +N   P   + LVE+   L IER  ED E+ V  + S+P   N  +V    RE KY LF +P  +L         +  +E  K+   + E F+    +LP     L Y K  +K+WK+
Sbjct:   26 KLVVKVYNDEDPTSKTIAIDQTWTSWEVCKKMMRKNDAEPDPNWVLVERLPELCIERSLEDHESVVDVVSSWPWENNNRIVINNKRE-KYALFKNPQNYLLSSDTSAGAAQLAEKSKD-ILLQEYFNESAMRLPELDGVL-YLKEGKKSWKK 174

HSP 2 Score: 48.9062 bits (115), Expect = 2.661e-6
Identity = 40/124 (32.26%), Postives = 53/124 (42.74%), Query Frame = 3

Query: 1182 KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK--TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNY---QTQIQFVADTLS 1538
            K  +K+ +K +  LR SGIY   K       DL  +I        Y       + KAPT Y F LK   Y E   K I YFCA    +   W    ++A  G  L  NY   Q +++ +A TL 
Sbjct:  166 KEGKKSWKKHYFALRASGIYYTPKGKTKSSRDLVCLIKFEFVNIYYGNASFKKKFKAPTDYCFILKHPEYHEVESKAIKYFCAEDVKTFNRWVVCIKLAKYGYQLLENYSETQDEMENLAFTLD 289

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Nematostella
Match: EDO27048 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAC3])

HSP 1 Score: 50.0618 bits (118), Expect = 3.279e-7
Identity = 40/124 (32.26%), Postives = 53/124 (42.74%), Query Frame = 3

Query: 1182 KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLK--TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNY---QTQIQFVADTLS 1538
            K  +K+ +K +  LR SGIY   K       DL  +I        Y       + KAPT Y F LK   Y E   K I YFCA    +   W    ++A  G  L  NY   Q +++ +A TL 
Sbjct:   20 KEGKKSWKKHYFALRASGIYYTPKGKTKSSRDLVCLIKFEFVNIYYGNASFKKKFKAPTDYCFILKHPEYHEVESKAIKYFCAEDVKTFNRWVVCIKLAKYGYQLLENYSETQDEMENLAFTLD 143

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
Match: GRB14 (growth factor receptor bound protein 14 [Source:NCBI gene;Acc:101155810])

HSP 1 Score: 50.8322 bits (120), Expect = 1.608e-12
Identity = 50/190 (26.32%), Postives = 76/190 (40.00%), Query Frame = 1

Query:  691 KIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLT---------VYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNFSENEKERYYINEIFDGP--------FPQLPRYKSHLFYRKLHRKTWKR 1209
            + I   +E CF V    SS++  +   S+   P T         VY  + T K I +    TA +ICQL   +N+ +    ++L E  +HL IER  ED E+ V+ +LS         ++F     KY  F  P  +   +      E    N I D              P    +L  +   RK+WK+
Sbjct:   60 RCIKEKEESCFPVP-SPSSESQHTFLVSECLSPWTKCSATQVIKVYNEDNTSKAIEVPPDVTARDICQLFVMKNHCIDDHSWTLFEHWTHLGIERTIEDHES-VMEVLSVGGMDTDCRLYFRKNYAKYEFFKKPLVFFPDHMFSMSSE---TNGIVDASELIETFVKSSTCPEVHGYLHAKDQSRKSWKK 244

HSP 2 Score: 41.5874 bits (96), Expect = 1.608e-12
Identity = 26/105 (24.76%), Postives = 46/105 (43.81%), Query Frame = 3

Query: 1188 SQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNY 1502
            S+K+ +K +  LR SG+Y   K    +   LQ          +Y+ +       APT + FC+K+    + + +   CA  E +   W +  R+   G  L+ N+
Sbjct:  238 SRKSWKKFYFVLRRSGLYFSSKGTSKEPRHLQFFADF-TDCDIYSVLSARKLYGAPTEFAFCIKSTKSCSARDLKLLCADVEHTKTCWITAMRLLKFGMQLYQNF 341

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
Match: raph1b (ras-associated and pleckstrin homology domains-containing protein 1 [Source:NCBI gene;Acc:101163063])

HSP 1 Score: 61.2326 bits (147), Expect = 2.268e-9
Identity = 48/165 (29.09%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++      +SLVE  + L++ERIFED E  V  LL++    +  ++F E R +KY LF +P  +L      S  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  308 KLVIRVHMSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSPDWSLVETITELQMERIFEDHENLVENLLNWTRDSHNKLMFIE-RIEKYALFKNPQNYLLGRKETSEMADRNKE-ALLEECFCGGSVSVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 463

HSP 2 Score: 54.299 bits (129), Expect = 3.183e-7
Identity = 38/112 (33.93%), Postives = 53/112 (47.32%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGG--WSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L    H+    G    S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+VNYQ  ++
Sbjct:  448 KKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLD---HVNVNYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWINGIRIAKYGKQLYVNYQEAMK 556

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
Match: raph1b (ras-associated and pleckstrin homology domains-containing protein 1 [Source:NCBI gene;Acc:101163063])

HSP 1 Score: 61.2326 bits (147), Expect = 2.509e-9
Identity = 48/165 (29.09%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  781 KMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWL-----GSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV*EIRAFMLIKSQI 1260
            K+ + V+  + + KT+++DE  T  ++   L  +++      +SLVE  + L++ERIFED E  V  LL++    +  ++F E R +KY LF +P  +L      S  ++  KE   + E F G    +P  +  L+ +   +K+WK+       R F+L  S I
Sbjct:  308 KLVIRVHMSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSPDWSLVETITELQMERIFEDHENLVENLLNWTRDSHNKLMFIE-RIEKYALFKNPQNYLLGRKETSEMADRNKE-ALLEECFCGGSVSVPEIEGVLWLKDDGKKSWKK-------RYFLLRASGI 463

HSP 2 Score: 54.299 bits (129), Expect = 3.178e-7
Identity = 38/112 (33.93%), Postives = 53/112 (47.32%), Query Frame = 3

Query: 1191 QKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGG--WSQCKAPTPYGFCLK-TYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQ 1517
            +K+ +K +  LR SGIY   K       DL   + L    H+    G    S+ KAPT Y   LK    ++  +YI Y C     +L  W +  RIA  GK L+VNYQ  ++
Sbjct:  448 KKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLD---HVNVNYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWINGIRIAKYGKQLYVNYQEAMK 556

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
Match: grb10b (growth factor receptor bound protein 10 [Source:NCBI gene;Acc:101165586])

HSP 1 Score: 56.9954 bits (136), Expect = 3.982e-8
Identity = 38/111 (34.23%), Postives = 57/111 (51.35%), Query Frame = 3

Query: 1182 KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCL---KTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQ 1505
            +  +K+ +K +M LR SG+Y   K    +   LQL+  L  S +++T I G  Q  APT + FC+   K+ GE   K +   CA  E S   W + FR+   G  L+ NY+
Sbjct:  284 EVGRKSWKKVYMFLRRSGLYCSTKGASKEPRHLQLLADLEDS-NIFTVITGKKQHSAPTDFEFCIKPNKSRGEM--KELRMLCAEDEQSRTCWMTGFRLFKYGIILYQNYK 391

[Close]

BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
Match: grb7 (growth factor receptor-bound protein 7 [Source:NCBI gene;Acc:101166170])

HSP 1 Score: 55.8398 bits (133), Expect = 8.266e-8
Identity = 36/109 (33.03%), Postives = 56/109 (51.38%), Query Frame = 3

Query: 1188 SQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYI---AYFCAPSEASLRYWSSMFRIALKGKTLFVNYQ 1505
            S+K  +K +  LR SG+Y+  K +  +   LQ +  L  +L++YT +       APT + FC+K    +NP  +      CA +E +   W+S FR+   GK L  NYQ
Sbjct:  274 SRKAWKKVYFFLRRSGLYSSTKGSSKEPRHLQCVADLD-NLNVYTVVNSRKLYGAPTDFSFCIKP--SRNPTRVQDLKVLCAENEQTRTCWTSAFRLFKHGKQLQSNYQ 379

[Close]

BLAST of Ras associated and pleckstrin y vs. Planmine SMEST
Match: SMESG000058735.1 (SMESG000058735.1)

HSP 1 Score: 665.226 bits (1715), Expect = 0.000e+0
Identity = 354/360 (98.33%), Postives = 356/360 (98.89%), Query Frame = 1

Query:  142 MASDLSLEFIELEECLSNLQEIQKSLENDMSKNHRTEIVNEKTEMKTHLNKIQNEMNKIGNKTETEDKQIKSLFKDVESKKKSEMKSDFPTNKQICTDLDQLIQMMKQSETKKDIDNYEENNKIWTPKIKEQNHNNDNLLNDTXXXXXXXXXXXXXXXXDQHNQNLIARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            MASDLSLEFIELEECLSNLQEIQKSLENDMSKNHRTEIVNEKTEMKTHLNK    MNKIGNKTETEDKQIKSLFKDVESKKKSEMKSDFPTN+QICTDLDQLIQMMKQSETKKDIDNYEENNKIWTPKIKEQNHNNDNLLNDTRKLKSSSLSRMKNMKLDQHNQNLIARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNF+ENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV
Sbjct:    1 MASDLSLEFIELEECLSNLQEIQKSLENDMSKNHRTEIVNEKTEMKTHLNK----MNKIGNKTETEDKQIKSLFKDVESKKKSEMKSDFPTNRQICTDLDQLIQMMKQSETKKDIDNYEENNKIWTPKIKEQNHNNDNLLNDTRKLKSSSLSRMKNMKLDQHNQNLIARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKTSSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNFAENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 356

HSP 2 Score: 294.664 bits (753), Expect = 2.283e-93
Identity = 139/150 (92.67%), Postives = 142/150 (94.67%), Query Frame = 3

Query: 1182 KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSFQEMNEIKLLPHLSKSLGCVTGRADLQTDL 1631
            K  +K  ++    LRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSFQEMNEIKLLPHLSKSLGCVTGRADLQTDL
Sbjct:  344 KLHRKTWKRSLCVLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPYGFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQIQFVADTLSSFQEMNEIKLLPHLSKSLGCVTGRADLQTDL 493

[Close]

BLAST of Ras associated and pleckstrin y vs. Planmine SMEST
Match: SMESG000002146.1 (SMESG000002146.1)

HSP 1 Score: 87.0409 bits (214), Expect = 9.154e-18
Identity = 44/141 (31.21%), Postives = 79/141 (56.03%), Query Frame = 1

Query:  799 YQPNRTMKTILIDETTTAGEICQLLTARNYLMPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDREDKYGLFTDPGKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLHRKTWKRSLCV 1221
            +  ++T K ++I++T T   + ++L  +N+ +P +K ++VEK   LK+ER FE+ E  +  + S+P   + +M+FFE RED YGLF +  ++LG N+         I  +F         Y+ +++ +K    TWKR  C+
Sbjct:  266 FSSDKTTKALIINDTMTVESVIKVLMEKNFWIPSLKSAIVEKVPSLKMERFFEEHEILLDCVNSWPSTCS-NMIFFEQREDIYGLFENAKQYLGENYPLGAMNVDAIKNLFYTLSAMQHDYQDYIYIKKPSENTWKRKFCL 405

HSP 2 Score: 62.3882 bits (150), Expect = 4.682e-10
Identity = 36/111 (32.43%), Postives = 54/111 (48.65%), Query Frame = 3

Query: 1182 KTSQKNLEKEFMCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWS-QCKAPTPYGFCLKTYGEQNPKY--IAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQ 1505
            K S+   +++F  L ++GI   +K           ++ L     LYTT GGW+ +  APTP+GF  K Y   +PK   +  FCA  E S++ W S  R+      +  NYQ
Sbjct:  393 KPSENTWKRKFCLLNHNGITTIQKKKSKGLKSHCNVMELKDKYCLYTTTGGWTKEWNAPTPFGFAFKPYSIVDPKSTEVIMFCASDEVSMKRWCSNLRLCKYKNQILNNYQ 503

The following BLAST results are available for this feature:

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
BLAST of Ras associated and pleckstrin y vs. Ensembl Celegans
BLAST of Ras associated and pleckstrin y vs. Ensembl Fly
BLAST of Ras associated and pleckstrin y vs. Ensembl Zebrafish
BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
BLAST of Ras associated and pleckstrin y vs. TrEMBL
BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
BLAST of Ras associated and pleckstrin y vs. Ensembl Sea Lamprey
BLAST of Ras associated and pleckstrin y vs. Ensembl Yeast
BLAST of Ras associated and pleckstrin y vs. Ensembl Nematostella
BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
BLAST of Ras associated and pleckstrin y vs. Planmine SMEST

BLAST of Ras associated and pleckstrin y vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRB10	1.279e-17	32.74	growth factor receptor bound protein 10 [Source:HG...	[more]
GRB10	1.486e-17	32.74	growth factor receptor bound protein 10 [Source:HG...	[more]
GRB10	1.486e-17	32.74	growth factor receptor bound protein 10 [Source:HG...	[more]
GRB10	1.486e-17	32.74	growth factor receptor bound protein 10 [Source:HG...	[more]
GRB10	1.486e-17	32.74	growth factor receptor bound protein 10 [Source:HG...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mig-10	3.785e-11	35.04	Abnormal cell migration protein 10 [Source:UniPro...	[more]
mig-10	3.785e-11	35.04	Abnormal cell migration protein 10 [Source:UniPro...	[more]
mig-10	4.233e-11	35.04	Abnormal cell migration protein 10 [Source:UniPro...	[more]
mig-10	4.233e-11	35.04	Abnormal cell migration protein 10 [Source:UniPro...	[more]
mig-10	4.233e-11	35.04	Abnormal cell migration protein 10 [Source:UniPro...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
pico	8.772e-17	32.12	gene:FBgn0261811 transcript:FBtr0074804	[more]
pico	1.026e-16	32.12	gene:FBgn0261811 transcript:FBtr0303995	[more]
pico	2.017e-15	32.12	gene:FBgn0261811 transcript:FBtr0074805	[more]
pico	2.017e-15	32.12	gene:FBgn0261811 transcript:FBtr0303996	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grb7	8.512e-12	31.13	growth factor receptor bound protein 7 [Source:ZFI...	[more]
wu:fj59g11	1.412e-10	28.48	wu:fj59g11 [Source:ZFIN;Acc:ZDB-GENE-030131-8202]	[more]
grb10a	7.514e-9	33.33	growth factor receptor-bound protein 10a [Source:Z...	[more]
grb10a	7.514e-9	33.33	growth factor receptor-bound protein 10a [Source:Z...	[more]
raph1b	1.088e-8	28.48	Ras association (RalGDS/AF-6) and pleckstrin homol...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nr1d2	6.450e-17	33.33	nuclear receptor subfamily 1 group D member 2 [Sou...	[more]
nr1d2	8.479e-17	33.33	nuclear receptor subfamily 1 group D member 2 [Sou...	[more]
nr1d2	1.939e-15	31.45	nuclear receptor subfamily 1 group D member 2 [Sou...	[more]
nr1d2	2.942e-15	33.33	nuclear receptor subfamily 1 group D member 2 [Sou...	[more]
rock1	1.159e-8	33.94	Rho-associated, coiled-coil containing protein kin...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Raph1	1.089e-11	29.70	Ras association (RalGDS/AF-6) and pleckstrin homol...	[more]
Raph1	2.161e-11	29.70	Ras association (RalGDS/AF-6) and pleckstrin homol...	[more]
Grb14	1.544e-10	34.62	growth factor receptor bound protein 14 [Source:MG...	[more]
Raph1	8.350e-10	29.70	Ras association (RalGDS/AF-6) and pleckstrin homol...	[more]
Apbb1ip	5.498e-7	30.89	amyloid beta (A4) precursor protein-binding, famil...	[more]

BLAST of Ras associated and pleckstrin y vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P34400\|MIG10_CAEEL	6.336e-10	35.04	Abnormal cell migration protein 10 OS=Caenorhabdit...	[more]
sp\|Q9JLM9\|GRB14_MOUSE	1.080e-9	34.62	Growth factor receptor-bound protein 14 OS=Mus mus...	[more]
sp\|Q70E73\|RAPH1_HUMAN	3.692e-9	29.70	Ras-associated and pleckstrin homology domains-con...	[more]
sp\|B5KFD7\|GRB10_PIG	4.354e-9	33.33	Growth factor receptor-bound protein 10 OS=Sus scr...	[more]
sp\|Q13322\|GRB10_HUMAN	2.301e-8	31.85	Growth factor receptor-bound protein 10 OS=Homo sa...	[more]

BLAST of Ras associated and pleckstrin y vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A068YJN4	6.977e-41	40.13	Growth factor receptor bound protein OS=Echinococc...	[more]
A0A068WG15	3.709e-40	39.47	Growth factor receptor bound protein OS=Echinococc...	[more]
A0A564YP35	1.170e-38	38.16	Ras-associating domain-containing protein OS=Hymen...	[more]
A0A564YPY2	2.206e-38	38.16	Ras-associating domain-containing protein OS=Hymen...	[more]
W6URB4	6.210e-37	41.82	Ras-associated and pleckstriny domains-containing ...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wu:fj59g11	6.475e-11	29.09	Ras association (RalGDS/AF-6) and pleckstrin homol...	[more]
raph1b	7.406e-9	27.88	ras-associated and pleckstrin homology domains-con...	[more]
raph1b	7.443e-9	27.88	ras-associated and pleckstrin homology domains-con...	[more]
raph1b	7.861e-9	27.88	ras-associated and pleckstrin homology domains-con...	[more]
wu:fj59g11	8.025e-9	29.09	Ras association (RalGDS/AF-6) and pleckstrin homol...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
wu:fj59g11	5.220e-8	28.80	wu:fj59g11 [Source:ZFIN;Acc:ZDB-GENE-030131-8202]	[more]
apbb1ip	1.707e-7	26.37	amyloid beta (A4) precursor protein-binding, famil...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ras associated and pleckstrin y vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO35745	4.137e-10	32.89	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27048	3.279e-7	32.26	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ras associated and pleckstrin y vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRB14	1.608e-12	26.32	growth factor receptor bound protein 14 [Source:NC...	[more]
raph1b	2.268e-9	29.09	ras-associated and pleckstrin homology domains-con...	[more]
raph1b	2.509e-9	29.09	ras-associated and pleckstrin homology domains-con...	[more]
grb10b	3.982e-8	34.23	growth factor receptor bound protein 10 [Source:NC...	[more]
grb7	8.266e-8	33.03	growth factor receptor-bound protein 7 [Source:NCB...	[more]

BLAST of Ras associated and pleckstrin y vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000058735.1	2.283e-93	98.33	SMESG000058735.1	[more]
SMESG000002146.1	9.154e-18	31.21	SMESG000002146.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30011564 ID=SMED30011564|Name=Ras associated and pleckstrin y|organism=Schmidtea mediterranea sexual|type=transcript|length=1660bp
ATTAAATTCGCTTGCTTAGTAAATCTCTTACTGAAGATCAATGAATGCTT
AATTATAATTACTAATTTCTTATTGGTTGATTTTAATGATTGTGTCTCCT
TGTATTTATATCTATAACGGAGTTCTTAGATTGGCAATTCAATGGCTTCA
GATCTCTCGCTGGAATTTATCGAACTTGAAGAATGTTTATCTAACCTCCA
AGAAATACAAAAGAGTTTAGAAAATGATATGTCAAAGAATCATCGAACTG
AAATTGTTAATGAAAAGACGGAAATGAAAACCCATCTAAATAAAATTCAA
AATGAAATGAATAAAATCGGGAATAAAACCGAAACCGAAGATAAACAAAT
AAAATCTTTATTCAAAGATGTGGAATCCAAGAAAAAATCTGAAATGAAAT
CAGATTTTCCGACAAATAAACAAATTTGCACTGATCTGGATCAACTAATT
CAAATGATGAAACAATCGGAAACAAAAAAAGACATTGATAATTATGAGGA
AAACAACAAAATTTGGACACCAAAAATAAAAGAACAAAATCATAATAATG
ACAACTTACTAAATGACACTAGAAAGTTGAAATCGAGTTCATTGAGCAGA
ATGAAAAATATGAAGCTCGATCAACATAATCAAAATTTGATCGCACGATT
TTCAAATGAAAAACAATTATCATATTACGGATCATTGCCAAAAATAATAT
CAACAAATGATGAAGATTGTTTTACCGTAATTTATAAGACAAGTTCTCAG
ACAAATCTCAGTCACCCAACTTCTGATTACAAAATGCCTCTGACTGTTTA
TCAGCCTAACCGAACAATGAAAACGATCCTCATTGATGAGACCACCACTG
CCGGTGAAATTTGTCAGTTGTTAACTGCTAGAAATTATCTGATGCCTTGT
ATAAAATTCTCTCTTGTTGAAAAGACATCTCACTTAAAAATCGAAAGAAT
ATTCGAGGATGACGAAACGCCAGTATTATATTTACTCTCATATCCTGACG
GGGGTAATAAAAGCATGGTATTTTTTGAAGATCGAGAAGATAAATATGGG
CTATTTACTGATCCAGGAAAATGGCTTGGAAGCAATTTTTCTGAGAATGA
AAAAGAAAGATATTATATTAATGAGATCTTTGATGGCCCATTTCCTCAAT
TGCCACGTTACAAATCACATTTATTTTATAGAAAACTTCACAGAAAAACT
TGGAAAAGGAGTTTATGTGTTTAAGAAATTCGGGCATTTATGCTTATAAA
AAGTCAAATAAAAATGACTTTACAGACTTGCAGTTAATTATCAGTCTTCA
TCCCAGTCTTCATTTGTATACCACAATTGGAGGCTGGTCCCAATGTAAAG
CACCTACTCCCTATGGATTTTGTTTGAAAACTTATGGTGAGCAAAATCCA
AAGTATATTGCTTATTTTTGTGCCCCTTCAGAAGCTTCATTGAGATATTG
GTCATCGATGTTCAGAATTGCTTTAAAAGGAAAAACTTTATTCGTTAATT
ATCAAACTCAAATACAGTTTGTAGCAGATACTCTAAGCAGCTTCCAGGAA
ATGAATGAGATCAAATTATTGCCCCATCTGTCAAAATCTTTGGGATGTGT
TACTGGGAGAGCAGATTTGCAAACAGACCTCTGAAATCGGAACTAGAATC
AAAAATTTCC

protein sequence of SMED30011564-orf-1

>SMED30011564-orf-1 ID=SMED30011564-orf-1|Name=SMED30011564-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=361bp
MASDLSLEFIELEECLSNLQEIQKSLENDMSKNHRTEIVNEKTEMKTHLN
KIQNEMNKIGNKTETEDKQIKSLFKDVESKKKSEMKSDFPTNKQICTDLD
QLIQMMKQSETKKDIDNYEENNKIWTPKIKEQNHNNDNLLNDTRKLKSSS
LSRMKNMKLDQHNQNLIARFSNEKQLSYYGSLPKIISTNDEDCFTVIYKT
SSQTNLSHPTSDYKMPLTVYQPNRTMKTILIDETTTAGEICQLLTARNYL
MPCIKFSLVEKTSHLKIERIFEDDETPVLYLLSYPDGGNKSMVFFEDRED
KYGLFTDPGKWLGSNFSENEKERYYINEIFDGPFPQLPRYKSHLFYRKLH
RKTWKRSLCV*

protein sequence of SMED30011564-orf-2

>SMED30011564-orf-2 ID=SMED30011564-orf-2|Name=SMED30011564-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=140bp
MCLRNSGIYAYKKSNKNDFTDLQLIISLHPSLHLYTTIGGWSQCKAPTPY
GFCLKTYGEQNPKYIAYFCAPSEASLRYWSSMFRIALKGKTLFVNYQTQI
QFVADTLSSFQEMNEIKLLPHLSKSLGCVTGRADLQTDL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia

Vocabulary: **INTERPRO**
Term	Definition
IPR039664	GRB/APBB1IP
IPR011993	PH-like_dom_sf
IPR000159	RA_dom
IPR029071	Ubiquitin-like_domsf

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:3.10.20.90		coord: 208..298 e-value: 2.8E-18 score: 67.6
None	No IPR available	PANTHER	PTHR11243:SF37		coord: 47..357
None	No IPR available	CDD	cd17112	RA_MRL_like	coord: 213..291 e-value: 2.23667E-14 score: 65.7677
IPR000159	Ras-associating (RA) domain	PFAM	PF00788	RA	coord: 216..282 e-value: 1.2E-6 score: 29.0
IPR000159	Ras-associating (RA) domain	PROSITE	PS50200	RA	coord: 209..295 score: 10.732
IPR039664	GRB/APBB1IP	PANTHER	PTHR11243	GROWTH FACTOR RECEPTOR-BOUND PROTEIN	coord: 47..357
IPR029071	Ubiquitin-like domain superfamily	SUPERFAMILY	SSF54236	Ubiquitin-like	coord: 209..293

Main menu

Ras associated and pleckstrin y

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

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