Leishmanolysin-like peptidase

Overview
NameLeishmanolysin-like peptidase
Smed IDSMED30011562
Length (bp)2177
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Leishmanolysin-like peptidase (SMED30011562) t-SNE clustered cells

Violin plots show distribution of expression levels for Leishmanolysin-like peptidase (SMED30011562) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Leishmanolysin-like peptidase (SMED30011562) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Leishmanolysin-like peptidase (SMED30011562) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30011562

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30011562h1SMcG0017881 dd_Smed_v4_10609_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30011562h1SMcG0017881 dd_Smed_v4_10609_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011562h1SMcG0017881 dd_Smed_v4_10609_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011562h1SMcG0017881 dd_Smed_v6_10609_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30011562h1SMcG0017881 Contig46649uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30011562h1SMcG0017881 Contig46649newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Category 4 cellSMED30011562h1SMcG0017881 dd_Smed_v4_10609_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Leishmanolysin-like peptidase vs. Ensembl Human
Match: LMLN (leishmanolysin like peptidase [Source:HGNC Symbol;Acc:HGNC:15991])

HSP 1 Score: 249.595 bits (636), Expect = 3.862e-72
Identity = 181/639 (28.33%), Postives = 296/639 (46.32%), Query Frame = 3
Query:  162 IPRSDVKITNIHLNSMHNKRIKRDV-RNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCD 2018
            +P     I  +HL + H   +KRDV  +LRI   YDKS + L   K    KN + P A+ + E +  V+ PA + IL+ R C T  ++     +  + C  +C    KC   ++PE++L +C       +        D  G  +AD ++ V + ++  CS EN ++Y+  C+ E+ ++RP+ G  N+CPN I++  Q     +S +KHE++H LGF+A L+AF+ D DG P T R + G P   +  LGL   Y+ S++V+++ +     ++   ++ T ++LVTP + +EA++HF+C  L+G+ LE+ G   + L+H+E+R+L NE MT +      +SR T+A +EDTGWY+ +Y  A+K  + +  GCDFV K+C         +  I+ +   R +++                                                PYC  L  +   + C  +     VCNL++    +P +Y+YF E            G     A+YCP+ Q F    S     +  C    N      + G E YG  S C   K+  + ++C       D    C +  CS    L V V    Y C   G+ +  + +   +I  G L CP C   C+
Sbjct:   68 VPSDTEVINKVHLKANH--VVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLEKTFQVRRPAGT-ILLSRQCATN-QYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVYRGGKWPHGAVGVPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFNY-SLGL---YQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGMGCDFVRKSC---------KFWIDQQRQKRQMLS------------------------------------------------PYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGSGCYQVSCS-PQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCE 640          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Human
Match: LMLN (leishmanolysin like peptidase [Source:HGNC Symbol;Acc:HGNC:15991])

HSP 1 Score: 248.054 bits (632), Expect = 6.475e-72
Identity = 180/632 (28.48%), Postives = 294/632 (46.52%), Query Frame = 3
Query:  183 ITNIHLNSMHNKRIKRDV-RNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCD 2018
            I  +HL + H   +KRDV  +LRI   YDKS + L   K    KN + P A+ + E +  V+ PA + IL+ R C T  ++     +  + C  +C    KC   ++PE++L +C       +        D  G  +AD ++ V + ++  CS EN ++Y+  C+ E+ ++RP+ G  N+CPN I++  Q     +S +KHE++H LGF+A L+AF+ D DG P T R + G P   +  LGL   Y+ S++V+++ +     ++   ++ T ++LVTP + +EA++HF+C  L+G+ LE+ G   + L+H+E+R+L NE MT +      +SR T+A +EDTGWY+ +Y  A+K  + +  GCDFV K+C         +  I+ +   R +++                                                PYC  L  +   + C  +     VCNL++    +P +Y+YF E            G     A+YCP+ Q F    S     +  C    N      + G E YG  S C   K+  + ++C       D    C +  CS    L V V    Y C   G+ +  + +   +I  G L CP C   C+
Sbjct:   23 INKVHLKANH--VVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLEKTFQVRRPAGT-ILLSRQCATN-QYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVYRGGKWPHGAVGVPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFNY-SLGL---YQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGMGCDFVRKSC---------KFWIDQQRQKRQMLS------------------------------------------------PYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGSGCYQVSCS-PQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCE 588          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Human
Match: LMLN (leishmanolysin like peptidase [Source:HGNC Symbol;Acc:HGNC:15991])

HSP 1 Score: 193.741 bits (491), Expect = 3.256e-52
Identity = 118/352 (33.52%), Postives = 198/352 (56.25%), Query Frame = 3
Query:  162 IPRSDVKITNIHLNSMHNKRIKRDV-RNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTG 1196
            +P     I  +HL + H   +KRDV  +LRI   YDKS + L   K    KN + P A+ + E +  V+ PA + IL+ R C T  ++     +  + C  +C    KC   ++PE++L +C       +        D  G  +AD ++ V + ++  CS EN ++Y+  C+ E+ ++RP+ G  N+CPN I++  Q     +S +KHE++H LGF+A L+AF+ D DG P T R + G P   +  LGL   Y+ S++V+++ +     ++   ++ T ++LVTP + +EA++HF+C  L+G+ LE+ G   + L+H+E+R+L NE MT +      +SR T+A +EDTG
Sbjct:   68 VPSDTEVINKVHLKANH--VVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLEKTFQVRRPAGT-ILLSRQCATN-QYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVYRGGKWPHGAVGVPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFNY-SLGL---YQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTG 411          

HSP 2 Score: 56.225 bits (134), Expect = 1.891e-7
Identity = 49/192 (25.52%), Postives = 75/192 (39.06%), Query Frame = 3
Query: 1482 ESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCD 2018
            + ++PYC  L  +   + C  +     VCNL++    +P +Y+YF E            G     A+YCP+ Q F    S     +  C    N      + G E YG  S C   K+  + ++C       D    C +  CS    L V V    Y C   G+ +  + +   +I  G L CP C   C+
Sbjct:  413 QMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGSGCYQVSCS-PQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCE 603          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Human
Match: LMLN (leishmanolysin like peptidase [Source:HGNC Symbol;Acc:HGNC:15991])

HSP 1 Score: 192.2 bits (487), Expect = 4.610e-52
Identity = 117/345 (33.91%), Postives = 196/345 (56.81%), Query Frame = 3
Query:  183 ITNIHLNSMHNKRIKRDV-RNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTG 1196
            I  +HL + H   +KRDV  +LRI   YDKS + L   K    KN + P A+ + E +  V+ PA + IL+ R C T  ++     +  + C  +C    KC   ++PE++L +C       +        D  G  +AD ++ V + ++  CS EN ++Y+  C+ E+ ++RP+ G  N+CPN I++  Q     +S +KHE++H LGF+A L+AF+ D DG P T R + G P   +  LGL   Y+ S++V+++ +     ++   ++ T ++LVTP + +EA++HF+C  L+G+ LE+ G   + L+H+E+R+L NE MT +      +SR T+A +EDTG
Sbjct:   23 INKVHLKANH--VVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLEKTFQVRRPAGT-ILLSRQCATN-QYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVYRGGKWPHGAVGVPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFNY-SLGL---YQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTG 359          

HSP 2 Score: 55.8398 bits (133), Expect = 2.620e-7
Identity = 49/192 (25.52%), Postives = 75/192 (39.06%), Query Frame = 3
Query: 1482 ESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCD 2018
            + ++PYC  L  +   + C  +     VCNL++    +P +Y+YF E            G     A+YCP+ Q F    S     +  C    N      + G E YG  S C   K+  + ++C       D    C +  CS    L V V    Y C   G+ +  + +   +I  G L CP C   C+
Sbjct:  361 QMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGSGCYQVSCS-PQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCE 551          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Human
Match: LMLN2 (leishmanolysin like peptidase 2 [Source:HGNC Symbol;Acc:HGNC:53647])

HSP 1 Score: 75.8702 bits (185), Expect = 1.287e-13
Identity = 71/268 (26.49%), Postives = 122/268 (45.52%), Query Frame = 3
Query:  525 IDDIH---YELYRTSGE------DGAGAINAD--LIILVSYSSNGCSENS-LAYSTTCELESKINRPVLGSLNICPNKINSDQ-NLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLD-GIYLEDYGNANSVLSHFERRILYNELMTATIQ--DYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDF-VMKTC 1277
            I D H   Y L+   G       DG G  N D  L + V+++S    E S +AY+  C+L+S+ +RP+ G++  C   + S   +    + A  HE++H LGF+  L+  + D                +GF    + E   + + V            R +   + +L TP +     +H   S    G+ LE+      + SH+E R+L   LMTAT      + +   T+A  +D+GWYQ ++  A++ L+ + +G +F ++ TC
Sbjct:  129 IPDTHLRGYALWPEQGPPQLVQPDGPGVQNTDFLLYVRVAHTSKCHQEPSVIAYAACCQLDSE-DRPLAGTIVYCAQHLTSPSLSHSDIVMATLHELLHALGFSGQLFKKWRDCP--------------SGF---SVRENCSTRQLVT-----------RQDEWGQLLLTTPAVSLSLAKHLGVSGASLGVPLEE--EEGLLSSHWEARLLQGSLMTATFDGAQRTRLDPITLAAFKDSGWYQVNHSAAEELLWGQGSGPEFGLVTTC 365          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Celegans
Match: Y43F4A.1 (Leishmanolysin-like peptidase [Source:UniProtKB/Swiss-Prot;Acc:O62446])

HSP 1 Score: 257.684 bits (657), Expect = 1.041e-75
Identity = 209/715 (29.23%), Postives = 330/715 (46.15%), Query Frame = 3
Query:   84 LLFFKMILYFLVIL-LSGVIFISQSSFIPRSDVKITNIHLNSMHNKRIKRDVRN-------------LRILIHYDKSFDSLGN--KNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGC-SENSLAYSTTCELESKINRPVLGSLNICPNKI---NSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTI-SNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR-CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYK----YQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFVTVFDGCADPNGQCFNNTSFDIQCSGFQIKNLFLY 2147
            L+F     YFL  L  S  +  S  +  PR +  +  + +   H  R +R + +             LRI +HYDKS  +L    +N      +  AV +WE++L V+ P T+PI + R C + F + +  G R   C   C     C  A IP  +L  C   ++   +  +T+GE G G  + D I+ V+ + S  C    +L+Y+  C+ E+  +RP+ G++N+CP+ +   N D  +    S +KHEI+H LGF+  LYAFF D++G P T R+ +G P +   Q G  ++   S  +    +      E   I   H++VTP +++EA+ HF C  L+G  LE+ G   + L+H+E+R   NE MT T       SR T+AFLEDTGWYQP+Y  A+   + K  GCDF MK+C +++  K  ++  E+     S +                DGS+ +     +T++              +S+A  C  +P+ + +      +Y+   +L  G   P   KY+    G     A+YCP+ Q F     D T   +  C  +GN   K  +  LE YG++S CFEF     +R CG  +  S     C  ++C+      + V  Y     Y C  + + I        ++  G L CPKC   C N  C  P V + D   DP      +++F +    F    +FL+
Sbjct:    5 LIFIFFACYFLNFLPFSNQLPCSYQN--PRIEDILLEVPIEHEHPHRHRRGLPSSDPTSPPVEKFAPLRIQLHYDKSIQNLTAEVQNFVNTTLLPEAVGYWENALRVR-PMTTPIRLRRKCISSF-YYYKQGMRNVACDKGCRERTTCGEADIPRDHLLDCLACNNT--DDCKTTGELGEGVKDTDFILYVTAHDSKRCEGPETLSYAAHCQQEADFDRPIAGNVNLCPSALSVHNHDYEIL--TSTVKHEILHALGFSVGLYAFFRDSEGKPRTKRNRYGRPTSLNKQKGYYDW--DSNTITTVLRENWWTGEGKVIHPIHMMVTPKVREEARRHFGCDKLEGAELENQGGEGTYLTHWEKRAYENEAMTGTHTQNPVYSRLTLAFLEDTGWYQPNYEVAEDLHWGKQLGCDFAMKSCGEWIHEK--KILGEDAYPYCSDIKH--------------DGSKSMAITRCTTQR--------------DSLA-LCNLVPFQKELPS----QYRNFMSL-PGVN-PDGAKYY----GGSVEMADYCPFLQEFEWKLIDKTQHKDSRCELEGNG--KEGEDILEVYGANSKCFEFPKPWTERKCGRIRVLSHYMAGCYEHQCT---NGTLYVGSYNATDMYPCYAENQKIHIKKVVDGWLREGSLICPKCEDYCTN--CGPPIV-IPDYIGDPELDEPCSSNFKLSVLAFLCYLIFLH 660          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Fly
Match: Invadolysin (gene:FBgn0086359 transcript:FBtr0082181)

HSP 1 Score: 197.593 bits (501), Expect = 1.033e-53
Identity = 123/362 (33.98%), Postives = 188/362 (51.93%), Query Frame = 3
Query:  243 LRILIHYDKSFDSLGNK--NEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSG-EDGAGAINADLIILVSY-SSNGCSEN-SLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRD-SHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 1307
            LRIL+ YD+S   L  +  N      +  AV+FWE +L+V+      I + R C +  +    NG+    C D C     C    +P+ +L  C   +         S  + G G  NAD +  VS   +  C +  ++AY+  C+ E+ ++RP+ G  N+CP  I++  Q L   IS +KHEI+H LGF+ +LYAFF D+DG P TPR    G P   ++   L  +  S+E + K  +     +     +   ++VTP +  E + HFNC+ L+G  LED G   + L+H+E+RIL NE MT T       SR T+A +ED+GWY+ +Y  A    + K  GC F M++C D++Q   +R
Sbjct:   80 LRILLVYDESVYRLEEEKFNLINDTVLPEAVQFWEQALMVRE-TKGVIRLNRKCDS-TQVYVKNGH--THCIDHCKATTMCGEVQVPDAHLDVCRVCNATGQNCRIDSNTQPGEGIENADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKP---YLNEKLQIHQWSNETIRKVVRENWSVRGGHVNKVVDMMVTPRVIAEVRAHFNCNKLEGAELEDQGGEGTALTHWEKRILENEAMTGTHTQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCAFAMRSCKDWIQYNHAR 434          

HSP 2 Score: 70.8626 bits (172), Expect = 2.846e-12
Identity = 48/191 (25.13%), Postives = 81/191 (42.41%), Query Frame = 3
Query: 1485 SIAPYCKALPYSE-NMKCSDNLEYKEVCNL-RQGYQVPPKYKYF---------KENM-GSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR--CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLC 2015
            SI P+C  +       +C+D+     +CNL R  +++P  Y+ F         +E   G     A++CPY Q F     +  +    C    NN     +  LE+YG  + CF+      +   C  ++        C +Y+C +  RL +LV  Y Y+C + G+ +        ++  G + CP C  LC
Sbjct:  437 SIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSLNHVKDGEEGFYGGSVSLADHCPYIQEFTWRSKNVIVRGSHCRFTENNPRPEKNFALESYGEGAKCFDHSESMWEERSCHQTREWQHWGSGCYKYDC-FDGRLHILVGNYSYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELC 626          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Zebrafish
Match: lmln (leishmanolysin-like (metallopeptidase M8 family) [Source:ZFIN;Acc:ZDB-GENE-081104-298])

HSP 1 Score: 274.248 bits (700), Expect = 1.313e-81
Identity = 195/663 (29.41%), Postives = 305/663 (46.00%), Query Frame = 3
Query:  135 VIFISQSSFIPRSDVKITNIHLNSMHNKRIKRDV-------RNLRILIHYDKSFDSLGN-KNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWA-ISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYF-------KENMGSFD---HFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFV 2045
            +IFIS  +     D K+  +H   +H   +K D        + L I I YD S D L   K+   K+ + P A+ + + +  V+   + PIL+ R C T  ++     +  + C+  C    KC   V+PE +L +C    +           DG G   AD ++ VS  ++  C  EN +AY+  C+LES+++RP+ G  N+CPN I++    F   +S +KHEI+H LGF+A L+AF+ D+ G P TPR + G P      LGL   Y+ S++VIK        +    ++ T H+L TP + +EA+ HFNC  L+G+ LE+ G A + L+H+E+R+L NE MT +       SR T+A +EDTGWY+ +Y  A+   + +  GCDFVMK+C                                              W D+   K P L             +PYC ++  +   + C  +     VCNL++    +P +Y+YF       KE++ ++      A+YCP+ Q F          +  C  Q N      + G E YG  S C   K+  + ++C       D    C +  C+    LLV V    + C   G+ I  + R   ++++G+L CP CS  C N  C  P +
Sbjct:   24 IIFISTGAQTHTCDHKVP-LHTEVIHKVFLKPDRLTKRSTDQQLNIKIEYDSSLDGLDEAKSSLVKDKLLPQAIDYLQKAFRVRR-QSGPILLSRQCATN-QYLRKRDDPHRYCQGPCANVTKCGPVVVPEHHLQQCRVCSESGKSCGPVGPPDGEGVARADFVLYVSAMTTERCGQENIVAYAAYCQLESELDRPIAGYANLCPNMISTQPQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDGGKPLTPRSASGLPAYNE-SLGL---YQWSDKVIKRATRLWDIRGGQMVRHTVHLLATPRVVEEARRHFNCPILEGMELENQGGAGTELNHWEKRLLENEAMTGSHTQNRVFSRITLAIMEDTGWYRANYSMAENLQWGRGLGCDFVMKSCKF--------------------------------------------WIDQHRHKRPTL-------------SPYCDSVRSAPLQLTCRQDQLAVAVCNLQKFSNALPAEYQYFDHIPGVPKEDLSAYGGAVEIADYCPFSQEFSWHVGGEYQRSSYCRIQENQPATWRNYGAEQYGPGSVCLYQKSAFVMEQCTKRMTYPDWGSGCYKVSCT-AQGLLVWVQNETFLCVRTGQVISVSIRMNEWVYNGQLICPACSDFCSN--CPLPHL 619          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Zebrafish
Match: lmln (leishmanolysin-like (metallopeptidase M8 family) [Source:ZFIN;Acc:ZDB-GENE-081104-298])

HSP 1 Score: 259.996 bits (663), Expect = 8.239e-77
Identity = 182/622 (29.26%), Postives = 289/622 (46.46%), Query Frame = 3
Query:  237 RNLRILIHYDKSFDSLGN-KNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWA-ISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYF-------KENMGSFD---HFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFV 2045
            + L I I YD S D L   K+   K+ + P A+ + + +  V+   + PIL+ R C T  ++     +  + C+  C    KC   V+PE +L +C    +           DG G   AD ++ VS  ++  C  EN +AY+  C+LES+++RP+ G  N+CPN I++    F   +S +KHEI+H LGF+A L+AF+ D+ G P TPR + G P      LGL   Y+ S++VIK        +    ++ T H+L TP + +EA+ HFNC  L+G+ LE+ G A + L+H+E+R+L NE MT +       SR T+A +EDTGWY+ +Y  A+   + +  GCDFV         +KS +                                    W D+   K               +++PYC ++  +   + C  +     VCNL++    +P +Y+YF       KE++ ++      A+YCP+ Q F          +  C  Q N      + G E YG  S C   K+  + ++C       D    C +  C+    LLV V    + C   G+ I  + R   ++++G+L CP CS  C N  C  P +
Sbjct:   20 QQLNIKIEYDSSLDGLDEAKSSLVKDKLLPQAIDYLQKAFRVRR-QSGPILLSRQCATN-QYLRKRDDPHRYCQGPCANVTKCGPVVVPEHHLQQCRVCSESGKSCGPVGPPDGEGVARADFVLYVSAMTTERCGQENIVAYAAYCQLESELDRPIAGYANLCPNMISTQPQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDGGKPLTPRSASGLPAYNE-SLGL---YQWSDKVIKRATRLWDIRGGQMVRHTVHLLATPRVVEEARRHFNCPILEGMELENQGGAGTELNHWEKRLLENEAMTGSHTQNRVFSRITLAIMEDTGWYRANYSMAENLQWGRGLGCDFV---------MKSCKF-----------------------------------WIDQHRHK--------------PTLSPYCDSVRSAPLQLTCRQDQLAVAVCNLQKFSNALPAEYQYFDHIPGVPKEDLSAYGGAVEIADYCPFSQEFSWHVGGEYQRSSYCRIQENQPATWRNYGAEQYGPGSVCLYQKSAFVMEQCTKRMTYPDWGSGCYKVSCT-AQGLLVWVQNETFLCVRTGQVISVSIRMNEWVYNGQLICPACSDFCSN--CPLPHL 574          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Zebrafish
Match: si:ch211-216p19.5 (si:ch211-216p19.5 [Source:ZFIN;Acc:ZDB-GENE-160728-97])

HSP 1 Score: 83.5741 bits (205), Expect = 3.105e-16
Identity = 68/272 (25.00%), Postives = 122/272 (44.85%), Query Frame = 3
Query:  477 CSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCSENS--LAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWA-ISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRD--SHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLD-GIYLEDYGNA-NSVLSHFERRILYNELMTATIQDYSFV--SRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDF 1262
            C   +IP+++L  C    +  + +       G G  +AD ++ V ++++  C   S  LAY+  C+  S   RP+ G++ IC   +  ++  +   +  + HE+ H+LGF+  L + + D         D  SHG   +   Q G +  Y                             +P + +  Q+HFN +  D G  LE+   A + + SH+E R+L   +M A++ + S V     T+A L+DTGWY  ++ +A   ++ +  G DF
Sbjct:  121 CLGVIIPDEHLDGCSVYPNPEHPVPTVLRPRGPGVPDADFLLYVFTHNTEKCRAESSVLAYTAHCQTGSD-GRPLAGTMVICRETLKKERYTYQHFVKTVIHELFHVLGFSKELLSNWKDCTVSSQIGVDCWSHGQVTST-DQTGQVRLY-----------------------------SPTVIRAMQKHFNSTHTDLGAPLENKDAALDGLSSHWEARVLQGSIMAASLVEASLVRIDAITLAALQDTGWYSVNHSRAQSLVWGEGEGSDF 361          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Xenopus
Match: LMLN (leishmanolysin-like (metallopeptidase M8 family) [Source:NCBI gene;Acc:100487583])

HSP 1 Score: 99.7525 bits (247), Expect = 1.603e-21
Identity = 52/146 (35.62%), Postives = 86/146 (58.90%), Query Frame = 3
Query:  441 KICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYP 869
            + C   C    +    ++PE++L +C    +  +    +   DG G  + D ++ VS  ++  CS EN +AY+  C+LE++++RP+ G  N+CPN I++  Q     +S +KHEI+H LGF+A L+AF+ D+DG P TPR  +G P
Sbjct:   31 RYCHGACSESTRSGPVIVPEEHLQQCRVCSETQWHCGPSGPPDGPGIPDTDFVLYVSAMTTERCSQENIVAYAAYCQLEAEMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEIIHALGFSAGLFAFYYDDDGNPLTPRYINGLP 176          

HSP 2 Score: 64.6994 bits (156), Expect = 2.694e-10
Identity = 45/194 (23.20%), Postives = 86/194 (44.33%), Query Frame = 3
Query: 1476 KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCD 2018
            K++ ++P+C  +  +   + C  + +   +CNL++    +P +Y+YF +          + G     A++CP+ Q FR  +S     +  C    N      + G E YG  SAC E ++  + ++C       D    C +  C+    L V V+   Y C   G+ ++   +  ++++ G L CP C   C+
Sbjct:  218 KNQRLSPFCDTVRSNPLQLTCRQDQKAVAICNLQRFASPLPQEYQYFDDIPGVLADDLPHYGGAVEIADFCPFAQEFRWHQSGEFQRSSDCRAPENQPASSKNYGAERYGPGSACLEQRSAFVMEQCTKRMSYPDWGSGCYQVSCTE-DGLQVWVHDTPYLCTKWGQILRVRVQMNAWLYDGNLVCPPCPDFCE 410          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Mouse
Match: Lmln (leishmanolysin-like (metallopeptidase M8 family) [Source:MGI Symbol;Acc:MGI:2444736])

HSP 1 Score: 250.366 bits (638), Expect = 1.211e-72
Identity = 185/638 (29.00%), Postives = 299/638 (46.87%), Query Frame = 3
Query:  171 SDVKITN-IHLNSMHNKRIKRDV-RNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDN 2021
            SD ++ N +HL + H    KRD   +LRI   YD+S + L   K    KN + P A+ + E +  V+ PA   IL+ R C T  ++     +  + C  +C +  KC   ++PE++L +C    +  +        D  G  +AD ++ V + ++  CS EN ++Y+  C+ E+K++RP+ G  N+CPN I++  Q     +S +KHEI+H LGF+A L+AF+ D DG P T R + G P   +  LGL   Y+ S++V+++ +     ++   ++ T ++LVTP + +EA++HFNC  L+G+ LE+ G   + L+H+E+R+L NE MT +      +SR T+A +EDTGWY+ +Y  A+K  + +  GC+FV                   R S +  + Q                        R  +++P               +PYC  L  +   + C  +     VCNL++    +PP+Y+YF E            G     A+YCP+ Q F    S     +  C    N      + G E YG  S C   K+  I ++C       D    C +  CS    L V V    Y C   G+ +    +   +I +G L CP C   C+ 
Sbjct:   59 SDTEVINKVHLKTNHV--TKRDADGHLRIKTIYDQSIEELLPEKRYLVKNKLFPQAISYLEKTFQVRRPAGR-ILLSRQCATN-QYLRKENDPHRYCTGECAVHTKCGPVIVPEEHLQQCRVCREGKWPCGAVGVLDPEGVRDADFVLYVGALATERCSHENIISYAAYCQQEAKMDRPIAGYANLCPNMISTQPQEFIGMLSTVKHEIIHALGFSAGLFAFYHDQDGNPLTSRSADGLPPFNY-SLGL---YQWSDKVVRKVERLWNVRDNKIVRHTVYLLVTPRVVEEARKHFNCPVLEGMELENQGGMGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGLGCEFV-------------------RKSCKFWIDQH-----------------------RQRRQVP---------------SPYCDTLRSNPLQLTCRQDQRAVAVCNLQRFPNPLPPEYQYFDELTGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPELFKNYGAEQYGPHSVCLLQKSAFIMEQCERKLSYPDWGSGCYQVSCS-PQGLKVWVQDTSYLCSRAGQVLPVRIQMNGWIHNGNLLCPSCWDFCEQ 630          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Mouse
Match: Gm29776 (predicted gene, 29776 [Source:MGI Symbol;Acc:MGI:5588935])

HSP 1 Score: 87.8113 bits (216), Expect = 1.915e-17
Identity = 78/275 (28.36%), Postives = 129/275 (46.91%), Query Frame = 3
Query:  477 CSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINAD--LIILVSYSSNGCSENS-LAYSTTCELESKINRPVLGSLNICPNKINSDQ-NLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNC-STLDGIYLEDYGNANSVLSHFERRILYNELMTATIQ--DYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDF-VMKTC 1277
            C  A IP+ +L + Y +   H  L +    DG G  NAD  L + V+++S    E S +AY+  C+L+S+ +RP+ G++  C   + S   +    + A  HE++H LGF+  L+  + D                      GL      S R         K   R + + + +L TP +     +H     TL G  LE+     S+ SH+E R+L   +MTAT     ++ +   T+A  ED+GWYQ ++  A++ L+ + +G DF ++ TC
Sbjct:  140 CLGAKIPDAHL-RGYSLWPEH-GLPQLIQPDGPGVQNADFLLYVQVAHTSKCHKEPSVIAYAACCQLDSE-DRPLAGTIVYCGQHLRSPTLSHDDIVMATLHELLHALGFSGQLFKMWRDCPS-------------------GLSARENCSTR---------KQVTRRDERGQLLLTTPAVSHSLAKHLGVPGTLQGAPLEE--KQGSLSSHWESRLLQGSIMTATFHGAQHTRLDPVTLAAFEDSGWYQVNHSAAEELLWGQGSGPDFGLVSTC 381          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Mouse
Match: Gm29776 (predicted gene, 29776 [Source:MGI Symbol;Acc:MGI:5588935])

HSP 1 Score: 68.1662 bits (165), Expect = 1.381e-11
Identity = 66/271 (24.35%), Postives = 109/271 (40.22%), Query Frame = 3
Query:  477 CSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNC-STLDGIYLEDYGNANSVLSHFERRILYNELMTATIQ--DYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDF-VMKTC 1277
            C  A IP+ +L + Y +   H  L +    DG G  NAD ++ V           +A+++ C  E+ +                             HE++H LGF+  L+  + D                      GL      S R         K   R + + + +L TP +     +H     TL G  LE+     S+ SH+E R+L   +MTAT     ++ +   T+A  ED+GWYQ ++  A++ L+ + +G DF ++ TC
Sbjct:  137 CLGAKIPDAHL-RGYSLWPEH-GLPQLIQPDGPGVQNADFLLYVQ----------VAHTSKCHKEATL-----------------------------HELLHALGFSGQLFKMWRDCPS-------------------GLSARENCSTR---------KQVTRRDERGQLLLTTPAVSHSLAKHLGVPGTLQGAPLEE--KQGSLSSHWESRLLQGSIMTATFHGAQHTRLDPVTLAAFEDSGWYQVNHSAAEELLWGQGSGPDFGLVSTC 336          
BLAST of Leishmanolysin-like peptidase vs. UniProt/SwissProt
Match: sp|Q61YG1|LMLN_CAEBR (Leishmanolysin-like peptidase OS=Caenorhabditis briggsae OX=6238 GN=CBG03556 PE=3 SV=2)

HSP 1 Score: 259.61 bits (662), Expect = 1.982e-75
Identity = 194/636 (30.50%), Postives = 305/636 (47.96%), Query Frame = 3
Query:  243 LRILIHYDKSFDSLGNK-NEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGC-SENSLAYSTTCELESKINRPVLGSLNICPNKI---NSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR-CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYK----YQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFVTVFDGCADP--NGQCFNNTSFDI 2108
            LRI +HYDKS  +L  +   F    + P AV +WE++L V+ P  +PI + R C + F + +  G R   C   C     C  A IP  +L  C   ++   +  +T+GE G G   +D I+ V+ ++S  C    +L+Y+  C+ E+  +RP+ G++N+CP+ +   N D  +    S +KHEI+H LGF+  LYAFF D DG P T R+ +G P +   Q G  ++ K++  +    + +    E   I    ++VTP +++EA+ HF C  L+G  LE+ G   +VL+H+E+R   NE MT T       SR T+AFLEDTGWYQP+Y  A+   + K  GCDF MK+C +++  K  R+  E+     S +                DG++ +     ++++              +S+A  C  +P+ + +      +Y+   +L  G   P   KY+    G     A+YCP+ Q F     +    +  C  +GN   K  +  LE YG +S CFEF     +R CG  +  S     C  Y+C+      + V  Y     Y C  + + +        ++  G L CPKCS  C  S C  P V + D   DP  +  CF  + F +
Sbjct:   70 LRIQLHYDKSIQNLTAEVQHFVNTTLLPEAVGYWENALRVR-PMKTPIRLRRKCISSF-YYYKQGMRNVACDKGCRERTTCGEADIPNDHLLDCLACNNT--DDCQTTGEMGEGVKESDFILYVTAHNSKRCEGPETLSYAAHCQQEADFDRPIAGNVNLCPSALSVHNHDYEIL--TSTVKHEILHALGFSVGLYAFFRDKDGKPRTKRNRYGRPTSLNKQRGYYDWDKNT--ITTVLREEWWTGEGKVIHPIQMMVTPKVREEARRHFGCDKLEGAELENQGGEGTVLTHWEKRAYENEAMTGTHTQNPVYSRLTLAFLEDTGWYQPNYEVAEDLHWGKQLGCDFAMKSCGEWIHQK--RILGEDAYPYCSDIKH--------------DGTKSMAITRCTSQR--------------DSLA-LCNLIPFQKELP----PQYRNFMSL-PGVN-PDGAKYY----GGSVEMADYCPFLQEFEWKMPEKEHKDSRCELEGNG--KEGEDILEVYGENSKCFEFPKPWTERKCGRIRVLSHYMAGCYEYQCT---NGTLYVGSYNATDMYPCYAENQKVHIKKVVDGWLREGSLICPKCSDYC--SSCGPPIV-IPDYIGDPELDEPCFAFSKFSV 648          
BLAST of Leishmanolysin-like peptidase vs. UniProt/SwissProt
Match: sp|O62446|LMLN_CAEEL (Leishmanolysin-like peptidase OS=Caenorhabditis elegans OX=6239 GN=Y43F4A.1 PE=3 SV=1)

HSP 1 Score: 257.684 bits (657), Expect = 1.325e-74
Identity = 209/715 (29.23%), Postives = 330/715 (46.15%), Query Frame = 3
Query:   84 LLFFKMILYFLVIL-LSGVIFISQSSFIPRSDVKITNIHLNSMHNKRIKRDVRN-------------LRILIHYDKSFDSLGN--KNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGC-SENSLAYSTTCELESKINRPVLGSLNICPNKI---NSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTI-SNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR-CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYK----YQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFVTVFDGCADPNGQCFNNTSFDIQCSGFQIKNLFLY 2147
            L+F     YFL  L  S  +  S  +  PR +  +  + +   H  R +R + +             LRI +HYDKS  +L    +N      +  AV +WE++L V+ P T+PI + R C + F + +  G R   C   C     C  A IP  +L  C   ++   +  +T+GE G G  + D I+ V+ + S  C    +L+Y+  C+ E+  +RP+ G++N+CP+ +   N D  +    S +KHEI+H LGF+  LYAFF D++G P T R+ +G P +   Q G  ++   S  +    +      E   I   H++VTP +++EA+ HF C  L+G  LE+ G   + L+H+E+R   NE MT T       SR T+AFLEDTGWYQP+Y  A+   + K  GCDF MK+C +++  K  ++  E+     S +                DGS+ +     +T++              +S+A  C  +P+ + +      +Y+   +L  G   P   KY+    G     A+YCP+ Q F     D T   +  C  +GN   K  +  LE YG++S CFEF     +R CG  +  S     C  ++C+      + V  Y     Y C  + + I        ++  G L CPKC   C N  C  P V + D   DP      +++F +    F    +FL+
Sbjct:    5 LIFIFFACYFLNFLPFSNQLPCSYQN--PRIEDILLEVPIEHEHPHRHRRGLPSSDPTSPPVEKFAPLRIQLHYDKSIQNLTAEVQNFVNTTLLPEAVGYWENALRVR-PMTTPIRLRRKCISSF-YYYKQGMRNVACDKGCRERTTCGEADIPRDHLLDCLACNNT--DDCKTTGELGEGVKDTDFILYVTAHDSKRCEGPETLSYAAHCQQEADFDRPIAGNVNLCPSALSVHNHDYEIL--TSTVKHEILHALGFSVGLYAFFRDSEGKPRTKRNRYGRPTSLNKQKGYYDW--DSNTITTVLRENWWTGEGKVIHPIHMMVTPKVREEARRHFGCDKLEGAELENQGGEGTYLTHWEKRAYENEAMTGTHTQNPVYSRLTLAFLEDTGWYQPNYEVAEDLHWGKQLGCDFAMKSCGEWIHEK--KILGEDAYPYCSDIKH--------------DGSKSMAITRCTTQR--------------DSLA-LCNLVPFQKELPS----QYRNFMSL-PGVN-PDGAKYY----GGSVEMADYCPFLQEFEWKLIDKTQHKDSRCELEGNG--KEGEDILEVYGANSKCFEFPKPWTERKCGRIRVLSHYMAGCYEHQCT---NGTLYVGSYNATDMYPCYAENQKIHIKKVVDGWLREGSLICPKCEDYCTN--CGPPIV-IPDYIGDPELDEPCSSNFKLSVLAFLCYLIFLH 660          
BLAST of Leishmanolysin-like peptidase vs. UniProt/SwissProt
Match: sp|Q8BMN4|LMLN_MOUSE (Leishmanolysin-like peptidase OS=Mus musculus OX=10090 GN=Lmln PE=2 SV=1)

HSP 1 Score: 250.366 bits (638), Expect = 8.472e-72
Identity = 185/638 (29.00%), Postives = 299/638 (46.87%), Query Frame = 3
Query:  171 SDVKITN-IHLNSMHNKRIKRDV-RNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDN 2021
            SD ++ N +HL + H    KRD   +LRI   YD+S + L   K    KN + P A+ + E +  V+ PA   IL+ R C T  ++     +  + C  +C +  KC   ++PE++L +C    +  +        D  G  +AD ++ V + ++  CS EN ++Y+  C+ E+K++RP+ G  N+CPN I++  Q     +S +KHEI+H LGF+A L+AF+ D DG P T R + G P   +  LGL   Y+ S++V+++ +     ++   ++ T ++LVTP + +EA++HFNC  L+G+ LE+ G   + L+H+E+R+L NE MT +      +SR T+A +EDTGWY+ +Y  A+K  + +  GC+FV                   R S +  + Q                        R  +++P               +PYC  L  +   + C  +     VCNL++    +PP+Y+YF E            G     A+YCP+ Q F    S     +  C    N      + G E YG  S C   K+  I ++C       D    C +  CS    L V V    Y C   G+ +    +   +I +G L CP C   C+ 
Sbjct:   59 SDTEVINKVHLKTNHV--TKRDADGHLRIKTIYDQSIEELLPEKRYLVKNKLFPQAISYLEKTFQVRRPAGR-ILLSRQCATN-QYLRKENDPHRYCTGECAVHTKCGPVIVPEEHLQQCRVCREGKWPCGAVGVLDPEGVRDADFVLYVGALATERCSHENIISYAAYCQQEAKMDRPIAGYANLCPNMISTQPQEFIGMLSTVKHEIIHALGFSAGLFAFYHDQDGNPLTSRSADGLPPFNY-SLGL---YQWSDKVVRKVERLWNVRDNKIVRHTVYLLVTPRVVEEARKHFNCPVLEGMELENQGGMGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGLGCEFV-------------------RKSCKFWIDQH-----------------------RQRRQVP---------------SPYCDTLRSNPLQLTCRQDQRAVAVCNLQRFPNPLPPEYQYFDELTGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPELFKNYGAEQYGPHSVCLLQKSAFIMEQCERKLSYPDWGSGCYQVSCS-PQGLKVWVQDTSYLCSRAGQVLPVRIQMNGWIHNGNLLCPSCWDFCEQ 630          
BLAST of Leishmanolysin-like peptidase vs. UniProt/SwissProt
Match: sp|Q29AK2|LMLN_DROPS (Leishmanolysin-like peptidase OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=GA17800 PE=3 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 4.246e-54
Identity = 126/365 (34.52%), Postives = 192/365 (52.60%), Query Frame = 3
Query:  243 LRILIHYDKSFDSLGNK--NEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSG-EDGAGAINADLIILVSY-SSNGCSEN-SLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSH-GYPNNGFIQLGLLEYYKSSE---RVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 1307
            LRIL+ YD S   L  +  N      +  AV+FWE +L+V+      I + R C +  +    NG+    C D+C     C    +P ++L  C   +         S  + G G  NAD +  VS   +  C +  ++AY+  C+ E+ ++RP+ G  N+CP  I++  Q L   IS +KHEI+H LGF+ +LYAFF D++G P TPR S  G P   F+   L  +  S+E   +V++E           E+    ++VTP +  EA+ HF+C  L+G  LED G   + L+H+E+RIL NE MT T       SR T+A +ED+GWY+ +Y  A    + K  GC F M++C D++Q+  +R
Sbjct:   80 LRILLVYDDSVYRLEEEKFNLINDTVLPEAVQFWEQALMVRE-TKGIIRLNRKCDS-TQVYVKNGH--THCIDQCKATTMCGEVQVPNEHLDVCRVCNATGQNCRIDSNTQPGDGIQNADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDEGRPRTPRKSETGKP---FLNEKLQIHQWSNETIRKVVRENWSVRGGHVNKEVD---MMVTPRVVAEARAHFDCDKLEGAELEDQGGEGTALTHWEKRILENEAMTGTHTQSPVFSRITLALMEDSGWYRANYSMATPLSWGKGLGCSFAMRSCKDWIQMNHAR 434          

HSP 2 Score: 72.4034 bits (176), Expect = 8.995e-12
Identity = 50/191 (26.18%), Postives = 82/191 (42.93%), Query Frame = 3
Query: 1485 SIAPYCKALPYSE-NMKCSDNLEYKEVCNL-RQGYQVPPKYKYFK--ENMGSFDH--------FAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR--CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLC 2015
            SI P+C  +       +C+D+     +CNL R  Y++P  Y+ F   +N+ S +          A++CPY Q F     +  +    C    NN     +  LE+YG  S CF+      +   C  ++        C +Y C +  RL +LV  Y Y+C + G+ +        ++  G + CP C  LC
Sbjct:  437 SIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHDYELPKSYQNFDSLQNVKSGEEGFYGGSVSLADHCPYIQEFTWRSKNIIVRGSHCRFVENNPKPEKNFALESYGHGSKCFDHSEAMWEERSCHQTREWQHWGSGCYKYTC-FDGRLHILVGNYTYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELC 626          
BLAST of Leishmanolysin-like peptidase vs. UniProt/SwissProt
Match: sp|Q9VH19|LMLN_DROME (Leishmanolysin-like peptidase OS=Drosophila melanogaster OX=7227 GN=Invadolysin PE=2 SV=2)

HSP 1 Score: 197.593 bits (501), Expect = 1.035e-52
Identity = 123/362 (33.98%), Postives = 188/362 (51.93%), Query Frame = 3
Query:  243 LRILIHYDKSFDSLGNK--NEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSG-EDGAGAINADLIILVSY-SSNGCSEN-SLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRD-SHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 1307
            LRIL+ YD+S   L  +  N      +  AV+FWE +L+V+      I + R C +  +    NG+    C D C     C    +P+ +L  C   +         S  + G G  NAD +  VS   +  C +  ++AY+  C+ E+ ++RP+ G  N+CP  I++  Q L   IS +KHEI+H LGF+ +LYAFF D+DG P TPR    G P   ++   L  +  S+E + K  +     +     +   ++VTP +  E + HFNC+ L+G  LED G   + L+H+E+RIL NE MT T       SR T+A +ED+GWY+ +Y  A    + K  GC F M++C D++Q   +R
Sbjct:   80 LRILLVYDESVYRLEEEKFNLINDTVLPEAVQFWEQALMVRE-TKGVIRLNRKCDS-TQVYVKNGH--THCIDHCKATTMCGEVQVPDAHLDVCRVCNATGQNCRIDSNTQPGEGIENADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKP---YLNEKLQIHQWSNETIRKVVRENWSVRGGHVNKVVDMMVTPRVIAEVRAHFNCNKLEGAELEDQGGEGTALTHWEKRILENEAMTGTHTQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCAFAMRSCKDWIQYNHAR 434          

HSP 2 Score: 70.8626 bits (172), Expect = 2.853e-11
Identity = 48/191 (25.13%), Postives = 81/191 (42.41%), Query Frame = 3
Query: 1485 SIAPYCKALPYSE-NMKCSDNLEYKEVCNL-RQGYQVPPKYKYF---------KENM-GSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR--CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLC 2015
            SI P+C  +       +C+D+     +CNL R  +++P  Y+ F         +E   G     A++CPY Q F     +  +    C    NN     +  LE+YG  + CF+      +   C  ++        C +Y+C +  RL +LV  Y Y+C + G+ +        ++  G + CP C  LC
Sbjct:  437 SIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSLNHVKDGEEGFYGGSVSLADHCPYIQEFTWRSKNVIVRGSHCRFTENNPRPEKNFALESYGEGAKCFDHSESMWEERSCHQTREWQHWGSGCYKYDC-FDGRLHILVGNYSYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELC 626          
BLAST of Leishmanolysin-like peptidase vs. TrEMBL
Match: T1KJK2 (Leishmanolysin-like peptidase OS=Tetranychus urticae OX=32264 GN=107364885 PE=3 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 1.171e-83
Identity = 203/675 (30.07%), Postives = 319/675 (47.26%), Query Frame = 3
Query:   90 FFKMILYFLVILLSGVIFISQS---SFIPRSDVKITNIHLNSMHNKRIKRDVR---NLRILIHYDKS-FDSLGNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGE-DGAGAINADLIILVSY-SSNGCSEN-SLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTR--HILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKENMGSFDHF-----------AEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR-CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSIC 2030
            F+ +IL++++++   +  ++     + IP    +I  +HL S  + R +RD+    NLRI +HYD S F+   +K     N I P A+ +W+ +L V  P  +PI+I R CP           + + C +KC     C   V+PE++L  C   +      +        AG  +AD +  +S   +  C +  ++AY+  C+ ES+  RP+ G  N+CP  I++  Q+L   +S +KHEI+H LGF+ +LYA+F D  GIP TP+  +G  +    +L + E+   SE+V+++ K       R+   T+  H++VTP + +E + HFNCS L+G  LED G   ++L+H+E+R+  NE MT T       SR T+AF+EDTGWY+P+Y  A    + KN GCDF MK+C ++         I+ R                      +DG                           +SI P+C+ +       +C+D  +   +CNLR+    +PP Y+ F    G    F           A+YCPY Q F     D  +    C    N+  +  +  LE+YG +S CF  K    +R C  S++       C +YEC      L + N   Y C Y  + IK       ++  G + CP C  LC NSIC
Sbjct:    5 FYYLILFYILLINFNLFIVTVGHICNHIPPKQKEIGFVHLESKSHNRKQRDINISNNLRIKVHYDSSAFELPRDKFNVINNTILPQALDYWQKALQV-TPLETPIIISRKCPNHEVLFPPKNPKHQHCIEKCEPKTTCGEVVVPEEHLDVCRVCNKEFANCHDVGKRPKDAGVKDADFVFYISAIQTERCQKGATVAYAAHCQQESQTERPIAGHANLCPRSISTKPQDLATLLSTVKHEILHALGFSISLYAYFRDKKGIPLTPKGKNGR-HEVNKELSVPEW---SEKVVRKIKRDKWLV-RSGYMTKDIHMVVTPRVVEEVRNHFNCSKLEGAELEDQGEDGTILTHWEKRVFENEAMTGTHTQSPVYSRITLAFMEDTGWYKPNYSMAQPLEWGKNLGCDFAMKSCKEW---------IDKRR---------------------RDG---------------------------KSIHPFCEKVKEEPLETECNDARDAVALCNLRRYDVNLPPLYQNFDSIKGVGQKFLLDRYGGSVSLADYCPYIQEFTWKSKDVVVRGSQCQFVENSPPQDKNFALESYGPNSRCFNHKEKWEERACSQSRHWQHWGSGCYKYECVDGKIHLEIAN-LTYVCDYKDQEIKIQRLVNGWLHMGTIICPSCDELCPNSIC 615          
BLAST of Leishmanolysin-like peptidase vs. TrEMBL
Match: A0A0L8GT61 (Leishmanolysin-like peptidase (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22028461mg PE=3 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 1.956e-79
Identity = 191/640 (29.84%), Postives = 303/640 (47.34%), Query Frame = 3
Query:  183 ITNIHLNSMHNKRIKRDVRNLRILIHYDKSFDSLGNK---NEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCSE-NSLAYSTTCELESKINRPVLGSLNICPNKIN-SDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXR-TEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDY---GNA-------NSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQ-VPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNV-NIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLC 2015
            I ++HL   H  R +   + LRI +HYDKS   L ++   +  +K+ +  AV++W+D+L V+     PI + R C +G +  +   N+   C+ +C     C    IPE++L  C+ +D        + G  G G  NAD I+ V + SS  C   N++AY+  C+ E  ++RPV G  +ICP  ++ S Q     +S IKHEI+H LGF A LYAF+ D DG P T R+  GY +N  I    L+ Y+ SE+V++  +      +   E ++  ++VTP + +E + HFNCSTL+G  LED    G          +  +H+E+R+  NE MT T      +SR T+A +EDTGWY+ +Y  A ++ + K+ GCDFV   CY++++ KS R     + S+     Q                   V WG   T                                 C++N     VCNL Q    +P KY++F E            G     A++CPY Q       D +I    CT++ NN+    +  LE YG++S CF    + ++Q CG +  +  +   C  +EC     L ++V   +++C  +G+ +     +      G + CP C+ +C
Sbjct:    2 IHDVHLEPAHIIRKRSVDQPLRIYLHYDKSVSLLPSRKYRDLLQKDILPKAVRYWQDTLRVR-ATRVPIRLRRKCQSG-KVGY--ENQTLFCRGECDKKTICGDITIPEEHLETCFCVDCDE----SSKGRRGPGVSNADFILYVATLSSERCRHGNTVAYAAYCQQERALDRPVAGYFSICPYFLSTSPQQTKQLLSTIKHEILHALGFTAGLYAFYRDQDGNPLTTRE--GY-DNKPIYNRTLDLYQPSEKVVRRIERPNWLLQSGQENRSVWMIVTPKVVEEVRRHFNCSTLEGAELEDQLMNGKTLADGLIDGTAFTHWEKRVFENEAMTGTYTQNPVISRITLALMEDTGWYRVNYDNAKEYEWGKDLGCDFVKTNCYEWIKNKSER-----KESIHPFCNQ-------------------VKWGQLHT--------------------------------DCTNNRHSVAVCNLVQHKSPLPEKYQHFSELEGVSSDDVKRFGGSVDLADHCPYLQELLWKSGDSSIRGSRCTEEHNNLDVKHNYFLEKYGNTSRCFNHDGMWHLQHCGKTVQTQHMGSGCYEFECDPEEGLSIIVQSKRHRCYKEGQKVSIFYDSTQLRHQGSIICPACNEIC 574          
BLAST of Leishmanolysin-like peptidase vs. TrEMBL
Match: F1Q5N1 (Leishmanolysin-like peptidase OS=Danio rerio OX=7955 GN=lmln PE=3 SV=1)

HSP 1 Score: 274.248 bits (700), Expect = 2.938e-78
Identity = 195/663 (29.41%), Postives = 305/663 (46.00%), Query Frame = 3
Query:  135 VIFISQSSFIPRSDVKITNIHLNSMHNKRIKRDV-------RNLRILIHYDKSFDSLGN-KNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWA-ISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQ-TRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYF-------KENMGSFD---HFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFV 2045
            +IFIS  +     D K+  +H   +H   +K D        + L I I YD S D L   K+   K+ + P A+ + + +  V+   + PIL+ R C T  ++     +  + C+  C    KC   V+PE +L +C    +           DG G   AD ++ VS  ++  C  EN +AY+  C+LES+++RP+ G  N+CPN I++    F   +S +KHEI+H LGF+A L+AF+ D+ G P TPR + G P      LGL   Y+ S++VIK        +    ++ T H+L TP + +EA+ HFNC  L+G+ LE+ G A + L+H+E+R+L NE MT +       SR T+A +EDTGWY+ +Y  A+   + +  GCDFVMK+C                                              W D+   K P L             +PYC ++  +   + C  +     VCNL++    +P +Y+YF       KE++ ++      A+YCP+ Q F          +  C  Q N      + G E YG  S C   K+  + ++C       D    C +  C+    LLV V    + C   G+ I  + R   ++++G+L CP CS  C N  C  P +
Sbjct:   24 IIFISTGAQTHTCDHKVP-LHTEVIHKVFLKPDRLTKRSTDQQLNIKIEYDSSLDGLDEAKSSLVKDKLLPQAIDYLQKAFRVRR-QSGPILLSRQCATN-QYLRKRDDPHRYCQGPCANVTKCGPVVVPEHHLQQCRVCSESGKSCGPVGPPDGEGVARADFVLYVSAMTTERCGQENIVAYAAYCQLESELDRPIAGYANLCPNMISTQPQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDGGKPLTPRSASGLPAYNE-SLGL---YQWSDKVIKRATRLWDIRGGQMVRHTVHLLATPRVVEEARRHFNCPILEGMELENQGGAGTELNHWEKRLLENEAMTGSHTQNRVFSRITLAIMEDTGWYRANYSMAENLQWGRGLGCDFVMKSCKF--------------------------------------------WIDQHRHKRPTL-------------SPYCDSVRSAPLQLTCRQDQLAVAVCNLQKFSNALPAEYQYFDHIPGVPKEDLSAYGGAVEIADYCPFSQEFSWHVGGEYQRSSYCRIQENQPATWRNYGAEQYGPGSVCLYQKSAFVMEQCTKRMTYPDWGSGCYKVSCT-AQGLLVWVQNETFLCVRTGQVISVSIRMNEWVYNGQLICPACSDFCSN--CPLPHL 619          
BLAST of Leishmanolysin-like peptidase vs. TrEMBL
Match: A0A016V404 (Leishmanolysin-like peptidase OS=Ancylostoma ceylanicum OX=53326 GN=Acey_s0019.g3832 PE=3 SV=1)

HSP 1 Score: 269.24 bits (687), Expect = 1.477e-76
Identity = 200/693 (28.86%), Postives = 332/693 (47.91%), Query Frame = 3
Query:   99 MILYFLVILLSGVIFISQSSFI-PRSDVKITNIHLNSMHNKRI----KRDVRNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYI---DDIHYELYRTSGEDGAGAINADLIILVSY-SSNGC-SENSLAYSTTCELESKINRPVLGSLNICPNKINS---DQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYM--QIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTI-SNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR-CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFVTVFDGCADPNGQCFNNTSFDIQCSG 2120
            ++L +   L    +  S  S+  PR +  +  + + S   +R     ++    LRI +HYD S   L   K  F  +++ P A  +WE  L V   A +PI + R C + + + F N  +   C   C     C  AVIP ++L +C Y    DD +     T+GE+G G  +AD ++ V+  S+  C S ++LAY+  C+ E++++RPV G +N+CP+ +++   D+ +   +S +KHEI+H LGF+  LYAFF D +G P T R+ +G P +   +LG  E+ +++  +    +      E   +   H++VTP +++EA++HF C  L+G  LE+ G   + L+H+E+R+  NE MT T       SR T+A LED+GWY+P+Y  A++  + +  GCDFV K+C +++  +I+   LP    N ++                   DG + +    R T +   L           ++ PY K LP          ++++    + +G   P   K++    G     A++CPY Q F     + TI  +  C  +GNN  +  +  LE YGSSS C +FK    +R CG  +  S     C  + C      + + +   Y C Y+G+H+     T+ ++  G + CP C   C  S C A          +   Q   +   D  CSG
Sbjct:   10 VVLLYTAALHHRHVTASPCSYRNPRVEDVLLEVPIESSRTRRSTSPQQKVFEALRIYLHYDDSVLELPAEKQLFVNSSLLPEAAGYWEKVLRVAR-ANAPIRLRRKCISSY-YYFRNERKTVACDRGCREWTTCGDAVIPPEHLLECSYCLSSDDCY-----TTGEEGHGIKDADFVLYVTAISTKRCDSVDTLAYAAHCQQEAELDRPVAGHVNLCPSSLSTHRHDREIL--LSTVKHEILHALGFSVGLYAFFRDENGKPRTRRNRYGKPISLNKELGYYEWDRNT--ITTILREDWWTGEGKVVHPVHMMVTPRVREEARQHFACDLLEGAELENQGGDGTALTHWEKRVFENEAMTGTHTQNPVYSRLTLALLEDSGWYKPNYENAEELHWGRKLGCDFVRKSCGEWINNKIEKGELPTPFCNEIK------------------HDGRKSL-AVTRCTSQRDSLALC--------NLVPYRKELP----------IQFRNFAKI-EGVS-PDGTKHY----GGSVELADFCPYSQEFEWKLPNTTIRRDSRCELEGNN--REGEDILEVYGSSSRCLDFKQPWRERKCGRVRSLSHYMAGCYEHVCRNGTLFIAVHDSPLYPCYYEGQHVHIKRITEGWLREGTIVCPACEEFC--SQCKA---------HEETEQYIGDPDLDEPCSG 635          
BLAST of Leishmanolysin-like peptidase vs. TrEMBL
Match: A0A016V1X9 (Leishmanolysin-like peptidase OS=Ancylostoma ceylanicum OX=53326 GN=Acey_s0019.g3832 PE=3 SV=1)

HSP 1 Score: 268.47 bits (685), Expect = 1.557e-76
Identity = 196/670 (29.25%), Postives = 323/670 (48.21%), Query Frame = 3
Query:  165 PRSDVKITNIHLNSMHNKRI----KRDVRNLRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYI---DDIHYELYRTSGEDGAGAINADLIILVSY-SSNGC-SENSLAYSTTCELESKINRPVLGSLNICPNKINS---DQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYM--QIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTI-SNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQR-CGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFVTVFDGCADPNGQCFNNTSFDIQCSG 2120
            PR +  +  + + S   +R     ++    LRI +HYD S   L   K  F  +++ P A  +WE  L V   A +PI + R C + + + F N  +   C   C     C  AVIP ++L +C Y    DD +     T+GE+G G  +AD ++ V+  S+  C S ++LAY+  C+ E++++RPV G +N+CP+ +++   D+ +   +S +KHEI+H LGF+  LYAFF D +G P T R+ +G P +   +LG  E+ +++  +    +      E   +   H++VTP +++EA++HF C  L+G  LE+ G   + L+H+E+R+  NE MT T       SR T+A LED+GWY+P+Y  A++  + +  GCDFV K+C +++  +I+   LP    N ++                   DG + +    R T +   L           ++ PY K LP          ++++    + +G   P   K++    G     A++CPY Q F     + TI  +  C  +GNN  +  +  LE YGSSS C +FK    +R CG  +  S     C  + C      + + +   Y C Y+G+H+     T+ ++  G + CP C   C  S C A          +   Q   +   D  CSG
Sbjct:    8 PRVEDVLLEVPIESSRTRRSTSPQQKVFEALRIYLHYDDSVLELPAEKQLFVNSSLLPEAAGYWEKVLRVAR-ANAPIRLRRKCISSY-YYFRNERKTVACDRGCREWTTCGDAVIPPEHLLECSYCLSSDDCY-----TTGEEGHGIKDADFVLYVTAISTKRCDSVDTLAYAAHCQQEAELDRPVAGHVNLCPSSLSTHRHDREIL--LSTVKHEILHALGFSVGLYAFFRDENGKPRTRRNRYGKPISLNKELGYYEWDRNT--ITTILREDWWTGEGKVVHPVHMMVTPRVREEARQHFACDLLEGAELENQGGDGTALTHWEKRVFENEAMTGTHTQNPVYSRLTLALLEDSGWYKPNYENAEELHWGRKLGCDFVRKSCGEWINNKIEKGELPTPFCNEIK------------------HDGRKSL-AVTRCTSQRDSLALC--------NLVPYRKELP----------IQFRNFAKI-EGVS-PDGTKHY----GGSVELADFCPYSQEFEWKLPNTTIRRDSRCELEGNN--REGEDILEVYGSSSRCLDFKQPWRERKCGRVRSLSHYMAGCYEHVCRNGTLFIAVHDSPLYPCYYEGQHVHIKRITEGWLREGTIVCPACEEFC--SQCKA---------HEETEQYIGDPDLDEPCSG 610          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Cavefish
Match: lmln (leishmanolysin like peptidase [Source:NCBI gene;Acc:103047341])

HSP 1 Score: 268.47 bits (685), Expect = 3.629e-79
Identity = 190/647 (29.37%), Postives = 308/647 (47.60%), Query Frame = 3
Query:  162 IPRSDVKITNIHLNSMHNKRIKRDV-RNLRILIHYDKSFDSLG-NKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQ-LGLLEYYKSSERVIXXXXXXXXXXXRTEIQTR-HILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQGYQ-VPPKYKYF-------KENM---GSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAP 2039
            +P     I N+HL     +  KR   + L+I I YD S D L  +K+   K+ + P A+ + + +  V+   T P+L+ R C T  ++     +  + C+  C    +C   ++P+++L +C    +           DG G   AD ++ VS  ++  C  EN +AY+  C+LE++++RP+ G  N+CPN I++  Q     +S +KHEI+H LGF+A L+AF+ D+DG P TPR + G P   F + LGL   Y+ S+RVI+        + R  ++   H++VTP + +EA+ HFNC  L+G+ LE+ G   + L+H+E+R+L NE MT +       SR T+A +EDTGWY+ +Y  A+   + K  GCDFVM         KS +  I+ +   R                                                 S+ PYC+++  +   + C  +     VCNL++  Q +P +Y+YF       +E++   G     A++CP+ Q F    S     +  C  Q N      +   E YG +S C   K+  + ++C  S    D    C +  C+ +  LLV V    + C   G+ +  N R   +++SG+L CP CS  C+N  C  P
Sbjct:   66 VPLPTEVIHNVHLKP--GRLTKRSTEQQLKIQIFYDSSLDVLDEDKSSLVKDKLFPQAIDYLQRAFRVRR-QTGPVLLSRQCSTN-QYLRKKDDPHRYCQGACADITRCGPVIVPDEHLQQCRVCSETGKSCGPVGPPDGEGVDRADFLLYVSAVTTERCGQENIVAYAAYCQLEAELDRPIAGYANLCPNMISTQLQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDDGKPLTPRFASGLP--AFNETLGL---YQWSDRVIRRSTRLWDIRGRHMVRHEVHLMVTPRVVEEARRHFNCPILEGMELENQGGMGTELNHWEKRLLENEAMTGSHTQNRVFSRITLAIMEDTGWYRANYSMAENLEWGKGLGCDFVM---------KSCKFWIDQQRHARL------------------------------------------------SLTPYCESVRGTPLQLSCRQDQLAVAVCNLQKYSQPLPTEYQYFDSIPGVPEEDLSMYGGAVEIADFCPFSQEFSWHLSGEYQRSSYCRIQENQPDSWRNYAAEEYGPNSVCLYQKSAFVMKQCKKSMTYPDWGSGCYKMTCTALG-LLVWVQDQSFLCVRTGQLLNVNVRINEWVYSGQLICPACSHFCNN--CPLP 643          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Cavefish
Match: lmln (leishmanolysin like peptidase [Source:NCBI gene;Acc:103047341])

HSP 1 Score: 267.7 bits (683), Expect = 4.649e-79
Identity = 190/647 (29.37%), Postives = 308/647 (47.60%), Query Frame = 3
Query:  162 IPRSDVKITNIHLNSMHNKRIKRDV-RNLRILIHYDKSFDSLG-NKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSD-QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQ-LGLLEYYKSSERVIXXXXXXXXXXXRTEIQTR-HILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQGYQ-VPPKYKYF-------KENM---GSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAP 2039
            +P     I N+HL     +  KR   + L+I I YD S D L  +K+   K+ + P A+ + + +  V+   T P+L+ R C T  ++     +  + C+  C    +C   ++P+++L +C    +           DG G   AD ++ VS  ++  C  EN +AY+  C+LE++++RP+ G  N+CPN I++  Q     +S +KHEI+H LGF+A L+AF+ D+DG P TPR + G P   F + LGL   Y+ S+RVI+        + R  ++   H++VTP + +EA+ HFNC  L+G+ LE+ G   + L+H+E+R+L NE MT +       SR T+A +EDTGWY+ +Y  A+   + K  GCDFVM         KS +  I+ +   R                                                 S+ PYC+++  +   + C  +     VCNL++  Q +P +Y+YF       +E++   G     A++CP+ Q F    S     +  C  Q N      +   E YG +S C   K+  + ++C  S    D    C +  C+ +  LLV V    + C   G+ +  N R   +++SG+L CP CS  C+N  C  P
Sbjct:   66 VPLPTEVIHNVHLKP--GRLTKRSTEQQLKIQIFYDSSLDVLDEDKSSLVKDKLFPQAIDYLQRAFRVRR-QTGPVLLSRQCSTN-QYLRKKDDPHRYCQGACADITRCGPVIVPDEHLQQCRVCSETGKSCGPVGPPDGEGVDRADFLLYVSAVTTERCGQENIVAYAAYCQLEAELDRPIAGYANLCPNMISTQLQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDDGKPLTPRFASGLP--AFNETLGL---YQWSDRVIRRSTRLWDIRGRHMVRHEVHLMVTPRVVEEARRHFNCPILEGMELENQGGMGTELNHWEKRLLENEAMTGSHTQNRVFSRITLAIMEDTGWYRANYSMAENLEWGKGLGCDFVM---------KSCKFWIDQQRHARL------------------------------------------------SLTPYCESVRGTPLQLSCRQDQLAVAVCNLQKYSQPLPTEYQYFDSIPGVPEEDLSMYGGAVEIADFCPFSQEFSWHLSGEYQRSSYCRIQENQPDSWRNYAAEEYGPNSVCLYQKSAFVMKQCKKSMTYPDWGSGCYKMTCTALG-LLVWVQDQSFLCVRTGQLLNVNVRINEWVYSGQLICPACSHFCNN--CPLP 643          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004358.1 (pep scaffold:Pmarinus_7.0:GL476418:369102:375246:1 gene:ENSPMAG00000003980.1 transcript:ENSPMAT00000004358.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.183 bits (326), Expect = 4.005e-34
Identity = 73/216 (33.80%), Postives = 121/216 (56.02%), Query Frame = 3
Query:  237 RNLRILIHYDKSFDSLGN-KNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFW-AISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYP 869
            + LR+ + YD S DSL N K +F K  + P AV + + +L V++P    IL+ R C T   F   + +  + C+  C    +C    +P+++L +C   D+            G G  +AD ++ VS   ++ C  E  +AY+  C+LE++++RP+ G  N+CP+K++ D       +S +KHE++H LGF+A L+AF+ D+DG P TPR  +G P
Sbjct:    1 QRLRVRLIYDSSVDSLPNEKRDFIKMRLFPEAVDYIQSALFVRSPGAK-ILLNRYCATNHYF-MKHRDPHRYCQSACAETTRCGPVTVPDEHLQQCRVCDEGGRNCGSIGPAGGPGEPDADYVLYVSALGTDRCQQEGVVAYAAYCQLEAQLDRPIAGYANLCPDKVSLDAGEQPDMLSTVKHEVIHALGFSAGLFAFYRDDDGQPLTPRYGNGLP 214          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002113.1 (pep scaffold:Pmarinus_7.0:GL501047:4779:9283:1 gene:ENSPMAG00000001917.1 transcript:ENSPMAT00000002113.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.6557 bits (213), Expect = 7.908e-19
Identity = 54/189 (28.57%), Postives = 83/189 (43.92%), Query Frame = 3
Query: 1488 IAPYCKAL-PYSENMKCSDNLEYKEVCNL-RQGYQVPPKYKYFK----------ENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNV-NIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLC 2015
            +AP+CK +  +   + C        +CNL R    +P  Y+Y            +  G     A+YCP+ Q F   E         C +  N   +  + GLETYG  SAC E  +  ++QRCG+ +   D    C R  CS    + V + G  + C + G+ I+   R   ++  G L+CP CS +C
Sbjct:   69 VAPFCKEVRGHPLRLGCGAGRSALVLCNLQRYTNPLPTHYQYLDFLPGVSSADMQLYGGLVEIADYCPFSQEFSWHEGGAFSRGSACQNPRNQPDERVNYGLETYGQESACIEQGSTFHMQRCGHKRAIPDWGSGCYRVTCSPKGGVTVWIGGMDFPCSHAGQAIRVAVRAGQWLHVGSLRCPPCSEVC 257          

HSP 2 Score: 61.2326 bits (147), Expect = 2.447e-10
Identity = 25/63 (39.68%), Postives = 36/63 (57.14%), Query Frame = 3
Query: 1113 LYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKS 1301
            L NE MT +       SRFT+A +EDTGWY  +Y  A+   + +  GC F M++C  +M  +S
Sbjct:    1 LQNEAMTGSHTQRRIFSRFTLALMEDTGWYHANYSHAEALGWGRGLGCVFAMQSCKAWMDHRS 63          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Nematostella
Match: EDO44382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW33])

HSP 1 Score: 245.743 bits (626), Expect = 5.198e-72
Identity = 177/628 (28.18%), Postives = 282/628 (44.90%), Query Frame = 3
Query:  243 LRILIHYDKSFDSL-GNKNEFKKNAIEP-AVKFWEDSLIVKNPATSPILIERTCPTGFRF----AFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGED---GAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFW-AISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRH--------ILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQGYQ-VPPKYKYFK------------------ENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFE-FKNVNIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKC 2003
            LR  + YD+S +SL   KN+     + P AV ++  +  V+ P   PI ++RTC     F           ++ CK++C+   +C    +P ++L +C   D    E  R  G++   G G    D ++ VS   ++ CS  N++AY++ C+ E  ++RPV G  N+CP+++++D   +   IS +KHE+ H LGF+A LYAF+ D  G P T R  HG P            Y     + +      K   R + Q RH        ++VTP + + A+EHFNC+TL+G  +E+ G   + L+H+E+R+  NE MT T       SR T+A +EDTGWY+ +Y  A+   + +N GC F  ++C               R  M+S V                                            ++S  P+C  L  +   M+C+ +     +CNLR+  Q +PP+Y+YF                   ++ G     A+YCP+YQ F  +  DGT     CT   N      +  LE+YG++S CFE  +    +R   ++   D    C RY C     + + +    Y C   G+ I+     +++  SG L CP C
Sbjct:   20 LRFEVVYDESIESLSAEKNQLVTEKLIPEAVHYFHYTFSVR-PIKIPIKLQRTCKNNAYFLKDETGTKLGDVQYCKEECVTT-RCGPVTVPARHLDQCRVCDARGLECVRMPGDEWASGPGITRRDFVLYVSSIQTSHCSVANAVAYASYCQQEHMLDRPVAGFANLCPDRLDTDPRHYSNLISTVKHEVYHALGFSAGLYAFYRDKQGAPLTQRRKHGLP-----------VYNDKTNLYQWSNKVVKKVTRKKWQVRHGHVTHSVSMIVTPRVVRVAREHFNCATLEGAEIENQGGTGTELTHWEKRLFENEAMTGTYTQNPVFSRLTLALMEDTGWYKANYSMAETLDWGRNLGCVFAKESC---------------RTWMQSHVAH------------------------------------------NKSSEPFCYTLKQAPLRMRCTHSKLSIALCNLRKYPQPLPPEYQYFSHLPKESSRKTREAVFADTDSYGGAVPLADYCPFYQKFTLTGMDGTKRETTCTVSENGPPAHGNYALESYGATSRCFEQGRPWQAKRGLLTRTMLDWGSGCYRYRCK--DGIKIDIGNQTYSCYKAGQRIEVRGVLRNWNVSGSLVCPPC 575          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Nematostella
Match: EDO33070 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST90])

HSP 1 Score: 223.016 bits (567), Expect = 3.226e-64
Identity = 174/616 (28.25%), Postives = 277/616 (44.97%), Query Frame = 3
Query:  225 KRDVRN-LRILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGN---RIKICKDKC-LLDPKCSLAVIPEKYLAKCY----YIDDIHYELYRTSGEDGAGAINADLIILVSYSSNGCSE-NSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTE-------IQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNV-NIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTK-SFIFSGKLKCPKCSLLC 2015
            +R+V N LRI + Y    + L       K  +  A++++ D+  V+      IL  R     +      G+   +++ CK  C    P C    +P   +A C     + +D H E   +SG    G  + D ++ V+ S   C +  +LAY+  C+ E  ++RPV G LNICP+K+N   +    ++  KHEI H LGF+ +LYAFF  ++G   TPR   G P         L  Y  S+R IK  + K     RT+         T  ++VTP +++E Q+HFNCS+L+G  LE+ G   + L+H+E+R+  NE MT      +  SR T+A +EDTGWY+ +++ A+   + KN GC FV  +C  ++  +  RL  +     ++L                 +  R     D+++  +  L             A Y + LP          +EY+   +L  G   P  Y       GS D  A++CPYYQ F  +     +    C    N   +  + GLE YGS + CF    V    +C     S D    C +Y C     L +++ G  YQC + G+ +    ++   ++  G + CP C  +C
Sbjct:    3 RRNVENSLRISLVY-LELEPLRLHVSVVKKVLSEAIQYFHDTFRVRQTVERIILDRRCLNDSYFLKNATGDGPGKVRFCKVACDASKPLCGPRNVPRSDVAACRVCNEHGEDCHAENNSSSG---VGKNDTDFVLYVTASMEKCEKRETLAYAAVCQQEGNVDRPVAGFLNICPDKMNVSNDQKELLATFKHEIFHALGFSPSLYAFFRYDNGTAITPRSDTGMPPYDLA----LGRYTWSDRTIKTIERKDWMI-RTDKGNNGMVSHTVQLMVTPRVQQEVQDHFNCSSLEGAELENQGGPGTELAHWEKRVFENEGMTGAFTQNAVFSRVTLALMEDTGWYRSNFKMAETLRWGKNLGCLFVNNSCKAWL-TQQQRLKEKAYPFCQTL-------------KNSTEAQRTYCSNDKTSVAMCNL-------------AQYTQPLP----------VEYQYFESL-AGINNPGLYG------GSVD-LADFCPYYQGFVWTSKGAGLLGSYCLSSSNQKTEEKNYGLEYYGSDAKCFLQGQVWEKSKCAVRWISVDWGSGCYKYRCDQ-DGLKIIIGGLTYQCYHPGQVLSIEMQSSDGWLHKGSIVCPSCQDIC 563          
BLAST of Leishmanolysin-like peptidase vs. Ensembl Medaka
Match: lmln (leishmanolysin like peptidase [Source:NCBI gene;Acc:101175034])

HSP 1 Score: 244.202 bits (622), Expect = 1.164e-70
Identity = 188/652 (28.83%), Postives = 296/652 (45.40%), Query Frame = 3
Query:  162 IPRSDVKITNIHLNSMH-NKRIKRDVRNLRILIHYDKS-----FDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVS-YSSNGCS-ENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWA-ISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQ-LGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRH---ILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAPYCKALPYSE-NMKCSDNLEYKEVCNLRQ-GYQVPPKYKYFKE----------NMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNI-QRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAP 2039
            +P     I +++L      KR   DV  L+I I YD S     F SL +K          A+ F + +  VK+    PIL+ R C T  ++     +  + C++ C    +C   ++P  +L +C    +       T   DG G   +D ++ VS  ++  C  EN +AY+  C+LE++++RP+ G  N+CP  I+S    F   +S +KHEI+H LGF+A L+AF+ D++G P TPR + G P   F + LGL   Y+ SE VI+          R  +  RH   ++VTP + +EA+ HFNC  L+G+ LE+ G A + L+H+E+R+L NE MT +       SR T+A +ED+GWY+ +Y  A +  + +  GCDFVMK+C         +L                                   W D+ +++               ++ PYC  +  S   + C  +     VCNL++   ++P +Y+YF +            G     A+YCP+ Q F    S     N  C    N      + G E YG  S C   K+  + ++C       D    C +  C+    L V V    + C   G+ +  + R   ++++G L CP CS  CDN  C  P
Sbjct:   42 VPSPAEVIHHVYLKPERLTKRSSPDVLQLKIKIIYDSSRCYKLFCSLQDK------LFPQAIDFLQRAFSVKH-RVGPILLSRLCATN-QYMRKRNDPHRYCQESCADVTRCGPVIVPHHHLQQCKVCSEFGKSCGPTGPPDGPGVEGSDFVLYVSGITTERCGQENIVAYAAYCQLEAELDRPIAGYANLCPTMISSQPQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDEGKPLTPRFASGLP--AFNESLGL---YQWSEAVIRRVSRLWDI--RGGVMVRHHVHVMVTPRVVEEARNHFNCPILEGMELENQGGAGTELNHWEKRLLENEAMTGSHTQNRVFSRLTLAIMEDSGWYRANYSLAQRLDWGRGLGCDFVMKSC---------KL-----------------------------------WMDKQSQR-------------RHAVTPYCNTVRSSPLQLTCRQDQLAVAVCNLQKYPEKLPLEYQYFDQISDVAADQLSFYGGAVEIADYCPFSQEFSWHLSGEYQRNSYCRVSENQPDWWRNYGAEEYGPDSVCLYQKSAFVMEQCFRKMTYPDWGSGCYKVSCT-PQGLAVFVQDRSFTCTRKGQLLSVSVRVSDWVYNGVLMCPACSDFCDN--CPLP 618          
BLAST of Leishmanolysin-like peptidase vs. Planmine SMEST
Match: SMESG000063815.1 (SMESG000063815.1)

HSP 1 Score: 791.186 bits (2042), Expect = 0.000e+0
Identity = 396/403 (98.26%), Postives = 397/403 (98.51%), Query Frame = 3
Query:   99 MILYFLVILLSGVIFISQSSFIPRSDVKITNIHLNSMHNKRIKRDVRNLRILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 1307
            MILYFLVILLSGVIFISQSSFIPR DVKITNIHLNS+HNKRIKRDVRNLRILIHYDKSFDSL NKNEFKKNAIEPAVKFWEDSLIVKNP TSPILIER CPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDD HYE YRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIKEEKYKAKYKERTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR
Sbjct:    1 MILYFLVILLSGVIFISQSSFIPRGDVKITNIHLNSIHNKRIKRDVRNLRILIHYDKSFDSLENKNEFKKNAIEPAVKFWEDSLIVKNPVTSPILIERICPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDSHYESYRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIKEEKYKAKYKERTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 403          

HSP 2 Score: 503.827 bits (1296), Expect = 2.087e-170
Identity = 232/234 (99.15%), Postives = 233/234 (99.57%), Query Frame = 3
Query: 1476 KHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICTAPFVTVFDGCADPNGQCFNNTSFDIQCSGFQIKNLFLYSFVLPIVVFW 2177
            +HESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSIC APFVTVFDGCADPNGQCFNNTSFDIQCSGFQIKNLFLYSFVLPIVVFW
Sbjct:  403 RHESIAPYCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSICNAPFVTVFDGCADPNGQCFNNTSFDIQCSGFQIKNLFLYSFVLPIVVFW 636          
BLAST of Leishmanolysin-like peptidase vs. Planmine SMEST
Match: SMESG000036783.1 (SMESG000036783.1)

HSP 1 Score: 236.498 bits (602), Expect = 1.811e-68
Identity = 134/400 (33.50%), Postives = 222/400 (55.50%), Query Frame = 3
Query:   99 MILYFLVILLSGVIFISQSSFIPRSDVKITNIHLN-SMHNKRIKRDVRNLRILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQD-YSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQ 1292
            M +  L+++L  +I + +SS     D  +T I ++ ++ N R ++   +LRI  HY  SF S  N +  KK  +EP+ +  E  L  KNP    + ++R C  G   +  N + I+ C + C+   KC    IPE+YL +C  I      +Y  S  +G G  N D+II+V+++   C++++ A + +C +E +++RP+LG + +C  K   + N+  ++  I+HEI+H LGF    YA+F  ++G+P  PRD  G P  G  +  +  YY  ++++IK+ +   +       +T    V  NI K AQEHF C  +D + LED G + S L+HF+  +L+N++MT    +    +S+FT+A L+DTGWY+ DY KA  + + K  GC   +K CY YM+
Sbjct:    1 MKITVLILVLQKLISV-ESSERQDLDEMVTGIEIDQNLQNYRTRKSSSHLRIHYHYTDSFGSYPNSDAIKKQIMEPSKEEIERMLKAKNPINGVLRVDRRCINGR--SRTNADGIRGCIEGCVAATKCLGITIPEEYLKRCRKILPSGEIIYSQS--EGPGIANVDIIIVVAFTH--CNDHTKASAASCFIEKQLDRPILGVIEMCIGKFQVNVNVIESVKIIQHEIIHALGFALNKYAYFRQSNGLPIVPRDEFGVPALG--KNNIERYYLWNDKIIKKVQRTRESVNGIYKKTMDAFVLENIVKVAQEHFGCPDIDAVDLEDAGGSGSALTHFDEYLLHNDIMTPQTNNALDVISKFTLALLQDTGWYEVDYSKAQDYDYGKGKGCTLPLKGCYRYME 391          
BLAST of Leishmanolysin-like peptidase vs. Planmine SMEST
Match: SMESG000008405.1 (SMESG000008405.1)

HSP 1 Score: 236.884 bits (603), Expect = 1.914e-68
Identity = 165/530 (31.13%), Postives = 249/530 (46.98%), Query Frame = 3
Query:  213 NKRIKRDV-RNLRILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLGSLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSHGYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQD-YSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSRLPIENRNSMRSLVTQRXXXXXXXXXXXXKDGSREV*WGDRSTKKIPKLLFWY*N**KHESIAP---YCKALPYSENMKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQSESDGTISNGICTD-QGNNVVKGFDKGLETYGSSSAC 1784
            N R+KR   +NLRI   Y  SF S       K N +EPA    +  +  K+P    +L++R+C        +N    K C   C    +C   V+P  YL  C  +D +    ++T+G DGAG  + D+++LV+Y++  CS N+LAY+ +C +E+ ++RP+LG +N+C N I+   N       I HEI+H LGF+   YAF+   DG P  PR+++G+PN G    G   YY  +E +IK    +            +  V PN+   A+ HF+C TL+ + LEDYG A+S  SHF+   L+NELMT        F+SR T+A L+DTGWY  D+     F + +  GC    K CY+YMQ++ S+    +     +LV                       +G+     I +  F+  N  K+ S+ P   Y K+LP                        +P     F   +  ++   EYCP Y          +  N +C D Q NNV+ G++     +GS S C
Sbjct:   49 NARLKRATSQNLRIYFDYQSSFTSSSFAEALKTNLMEPAKNVLQSIITPKSPNNGLLLVDRSCTN--SMMRLNSKNQKGCAYGCT-QTECLGIVVPSVYLKACKIVDSLGN--FQTTGSDGAGISDIDIVLLVTYTN--CSANTLAYAGSCFMENVLDRPILGVVNLCSNMIDPYTNTQSYTKVIIHEIIHSLGFSVDKYAFYRYQDGSPIVPRNAYGFPNLGVSANG---YYNWNENIIKPIVRQRNSVNSAYTVNFYGFVLPNVLAAARVHFDCPTLEAVDLEDYGGASSAYSHFDEYFLFNELMTPQSNGAMDFLSRITLALLQDTGWYNVDFSAVGNFDYGRKKGCVLPEKGCYNYMQMRESKSLTLDPLCNTALV-----------------------YGNILGCSIYRNYFYRCNLFKYTSVPPNLQYFKSLP-----------------------GIPSADVQFYAGLSPYN---EYCPGYW-------VSSKPNFVCNDMQNNNVITGYNSIPSYFGSDSMC 512          
BLAST of Leishmanolysin-like peptidase vs. Planmine SMEST
Match: SMESG000076084.1 (SMESG000076084.1)

HSP 1 Score: 230.335 bits (586), Expect = 2.222e-65
Identity = 137/374 (36.63%), Postives = 218/374 (58.29%), Query Frame = 3
Query:  216 KRIKRDVRNLRILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNR--IKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCSENS-LAYSTTCELESKINRPVLGSLNICPNKINSD-----QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSH-GYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 1307
            +R KR + NL+I  HYD SF+   +   +K   I+PA+++ +++L V+N   S I ++R C +  R AFV  N      C D C     C    +P ++L  C  I  ++  L +  G +G G  + D I+ + S  S  C ++S LAY+++C+ ES+++RP+ GS+N CP +++SD     Q+LF A    KHE++H LGF    +AF+ D +G P+TPR    G P+ GF+Q      Y  S RV +    + +      ++   ++V P + +EA+++FNCSTL G+ LED G     ++H+E+RIL N++MTAT    + VSR T+A + DTGWY P+Y  AD   + ++ GCDF+  +CY+Y+Q +S R
Sbjct:   98 RRRKRTLTNLKIHPHYDDSFNFQKHSFLYKTYIIQPAIEYLQNALYVRN-RYSNIKLQRKCDSN-RLAFVKINEEFSYYCGDGCSQRTTCGDVEVPLEHLMACRQI--MNSRLVKV-GAEGPGVNDTDFILYIESRQSKKCDDSSVLAYASSCQSESQLDRPIAGSINFCPGRLSSDFGHLSQSLFIA----KHELIHALGFAITQFAFYRDPNGAPYTPRSIFTGRPDLGFLQ-DRSNIYLWSNRVTRSTVRRWQSAVGFFLKNVTLMVLPTVVQEARKYFNCSTLTGVELEDQGGLGVSITHWEKRILENDIMTATFTQEARVSRITLALMYDTGWYIPNYELADYISWGRHLGCDFLEMSCYEYIQHRSIR 461          

HSP 2 Score: 85.8853 bits (211), Expect = 4.855e-17
Identity = 59/197 (29.95%), Postives = 89/197 (45.18%), Query Frame = 3
Query: 1476 KHESIAPYCKAL-PYSENMK--CSDNLEYKEVCNL-RQGYQVPPKYKYFKENM-------GSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEF-KNVNIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSIC 2030
            + +SI P+C  +  + E +   CS +      CNL +  YQ+ P+++YF ++        G     A YCPY Q F   + D       C++  NN     +  L+ +G  S+CF   K  ++  CG     S +   C ++ CS +  LLV VN   YQC   G+ I      + F  SG L CP C   C +S C
Sbjct:  461 RGQSIEPFCAIINRHEEELSGFCSADRHAYAYCNLDKHQYQLEPQHRYFTDDQIYQSSYYGGKSTAANYCPYPQEFNWYKGDRVSRTTQCSESRNNQNYQNNFLLQEFGPKSSCFALSKKWSVYSCGKKIVPSMIGAGCYKFTCSPLFGLLVTVNNQTYQCPSAGDIIAIEEANEYFSISGALICPVCIDYCPSSFC 657          
BLAST of Leishmanolysin-like peptidase vs. Planmine SMEST
Match: SMESG000076084.1 (SMESG000076084.1)

HSP 1 Score: 229.95 bits (585), Expect = 8.242e-65
Identity = 137/374 (36.63%), Postives = 218/374 (58.29%), Query Frame = 3
Query:  216 KRIKRDVRNLRILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTCPTGFRFAFVNGNR--IKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYELYRTSGEDGAGAINADLIILV-SYSSNGCSENS-LAYSTTCELESKINRPVLGSLNICPNKINSD-----QNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTPRDSH-GYPNNGFIQLGLLEYYKSSERVIXXXXXXXXXXXRTEIQTRHILVTPNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQDYSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIKSSR 1307
            +R KR + NL+I  HYD SF+   +   +K   I+PA+++ +++L V+N   S I ++R C +  R AFV  N      C D C     C    +P ++L  C  I  ++  L +  G +G G  + D I+ + S  S  C ++S LAY+++C+ ES+++RP+ GS+N CP +++SD     Q+LF A    KHE++H LGF    +AF+ D +G P+TPR    G P+ GF+Q      Y  S RV +    + +      ++   ++V P + +EA+++FNCSTL G+ LED G     ++H+E+RIL N++MTAT    + VSR T+A + DTGWY P+Y  AD   + ++ GCDF+  +CY+Y+Q +S R
Sbjct:  159 RRRKRTLTNLKIHPHYDDSFNFQKHSFLYKTYIIQPAIEYLQNALYVRN-RYSNIKLQRKCDSN-RLAFVKINEEFSYYCGDGCSQRTTCGDVEVPLEHLMACRQI--MNSRLVKV-GAEGPGVNDTDFILYIESRQSKKCDDSSVLAYASSCQSESQLDRPIAGSINFCPGRLSSDFGHLSQSLFIA----KHELIHALGFAITQFAFYRDPNGAPYTPRSIFTGRPDLGFLQ-DRSNIYLWSNRVTRSTVRRWQSAVGFFLKNVTLMVLPTVVQEARKYFNCSTLTGVELEDQGGLGVSITHWEKRILENDIMTATFTQEARVSRITLALMYDTGWYIPNYELADYISWGRHLGCDFLEMSCYEYIQHRSIR 522          

HSP 2 Score: 85.8853 bits (211), Expect = 4.514e-17
Identity = 59/197 (29.95%), Postives = 89/197 (45.18%), Query Frame = 3
Query: 1476 KHESIAPYCKAL-PYSENMK--CSDNLEYKEVCNL-RQGYQVPPKYKYFKENM-------GSFDHFAEYCPYYQNFRQSESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEF-KNVNIQRCGNSQYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIFSGKLKCPKCSLLCDNSIC 2030
            + +SI P+C  +  + E +   CS +      CNL +  YQ+ P+++YF ++        G     A YCPY Q F   + D       C++  NN     +  L+ +G  S+CF   K  ++  CG     S +   C ++ CS +  LLV VN   YQC   G+ I      + F  SG L CP C   C +S C
Sbjct:  522 RGQSIEPFCAIINRHEEELSGFCSADRHAYAYCNLDKHQYQLEPQHRYFTDDQIYQSSYYGGKSTAANYCPYPQEFNWYKGDRVSRTTQCSESRNNQNYQNNFLLQEFGPKSSCFALSKKWSVYSCGKKIVPSMIGAGCYKFTCSPLFGLLVTVNNQTYQCPSAGDIIAIEEANEYFSISGALICPVCIDYCPSSFC 718          
The following BLAST results are available for this feature:
BLAST of Leishmanolysin-like peptidase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LMLN3.862e-7228.33leishmanolysin like peptidase [Source:HGNC Symbol;... [more]
LMLN6.475e-7228.48leishmanolysin like peptidase [Source:HGNC Symbol;... [more]
LMLN3.256e-5233.52leishmanolysin like peptidase [Source:HGNC Symbol;... [more]
LMLN4.610e-5233.91leishmanolysin like peptidase [Source:HGNC Symbol;... [more]
LMLN21.287e-1326.49leishmanolysin like peptidase 2 [Source:HGNC Symbo... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Y43F4A.11.041e-7529.23Leishmanolysin-like peptidase [Source:UniProtKB/S... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Invadolysin1.033e-5333.98gene:FBgn0086359 transcript:FBtr0082181[more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lmln1.313e-8129.41leishmanolysin-like (metallopeptidase M8 family) [... [more]
lmln8.239e-7729.26leishmanolysin-like (metallopeptidase M8 family) [... [more]
si:ch211-216p19.53.105e-1625.00si:ch211-216p19.5 [Source:ZFIN;Acc:ZDB-GENE-160728... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
LMLN1.603e-2135.62leishmanolysin-like (metallopeptidase M8 family) [... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Lmln1.211e-7229.00leishmanolysin-like (metallopeptidase M8 family) [... [more]
Gm297761.915e-1728.36predicted gene, 29776 [Source:MGI Symbol;Acc:MGI:5... [more]
Gm297761.381e-1124.35predicted gene, 29776 [Source:MGI Symbol;Acc:MGI:5... [more]
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BLAST of Leishmanolysin-like peptidase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q61YG1|LMLN_CAEBR1.982e-7530.50Leishmanolysin-like peptidase OS=Caenorhabditis br... [more]
sp|O62446|LMLN_CAEEL1.325e-7429.23Leishmanolysin-like peptidase OS=Caenorhabditis el... [more]
sp|Q8BMN4|LMLN_MOUSE8.472e-7229.00Leishmanolysin-like peptidase OS=Mus musculus OX=1... [more]
sp|Q29AK2|LMLN_DROPS4.246e-5434.52Leishmanolysin-like peptidase OS=Drosophila pseudo... [more]
sp|Q9VH19|LMLN_DROME1.035e-5233.98Leishmanolysin-like peptidase OS=Drosophila melano... [more]
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BLAST of Leishmanolysin-like peptidase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1KJK21.171e-8330.07Leishmanolysin-like peptidase OS=Tetranychus urtic... [more]
A0A0L8GT611.956e-7929.84Leishmanolysin-like peptidase (Fragment) OS=Octopu... [more]
F1Q5N12.938e-7829.41Leishmanolysin-like peptidase OS=Danio rerio OX=79... [more]
A0A016V4041.477e-7628.86Leishmanolysin-like peptidase OS=Ancylostoma ceyla... [more]
A0A016V1X91.557e-7629.25Leishmanolysin-like peptidase OS=Ancylostoma ceyla... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lmln3.629e-7929.37leishmanolysin like peptidase [Source:NCBI gene;Ac... [more]
lmln4.649e-7929.37leishmanolysin like peptidase [Source:NCBI gene;Ac... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000004358.14.005e-3433.80pep scaffold:Pmarinus_7.0:GL476418:369102:375246:1... [more]
ENSPMAT00000002113.17.908e-1928.57pep scaffold:Pmarinus_7.0:GL501047:4779:9283:1 gen... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO443825.198e-7228.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO330703.226e-6428.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Leishmanolysin-like peptidase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lmln1.164e-7028.83leishmanolysin like peptidase [Source:NCBI gene;Ac... [more]
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BLAST of Leishmanolysin-like peptidase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000063815.12.087e-17098.26SMESG000063815.1[more]
SMESG000036783.11.811e-6833.50SMESG000036783.1[more]
SMESG000008405.11.914e-6831.13SMESG000008405.1[more]
SMESG000076084.12.222e-6536.63SMESG000076084.1[more]
SMESG000076084.18.242e-6536.63SMESG000076084.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011562 ID=SMED30011562|Name=Leishmanolysin-like peptidase|organism=Schmidtea mediterranea sexual|type=transcript|length=2177bp
ATCAAGTTTGTTTATCTACATAAAATATTTTCAAATATATCATGTAATTA
TTTAAAAATCATTTTATTAATATTTTTGAAGATTTATTGTTTTTTAAAAT
GATATTATATTTTTTGGTTATCTTACTTTCTGGCGTCATTTTTATCTCAC
AGTCTAGTTTCATACCTCGGAGTGATGTTAAAATTACCAATATTCATCTT
AACTCAATGCATAATAAAAGGATAAAGCGAGATGTCAGAAATTTGAGAAT
ACTAATTCATTATGATAAGTCTTTCGACTCTCTGGGAAATAAAAATGAAT
TTAAGAAAAATGCGATTGAACCAGCTGTCAAATTTTGGGAAGATTCTTTA
ATCGTTAAAAATCCAGCAACTTCTCCAATATTGATAGAAAGAACATGTCC
CACTGGCTTCAGATTCGCATTTGTGAATGGGAATAGAATTAAAATTTGCA
AAGACAAATGCTTGTTGGATCCCAAATGTTCTCTTGCTGTTATTCCTGAA
AAATATTTAGCAAAATGCTACTATATTGACGACATACATTATGAATTGTA
TAGAACATCTGGTGAAGACGGCGCTGGAGCAATAAATGCTGATTTAATTA
TTTTGGTTTCTTATAGTTCCAATGGTTGCTCGGAGAACTCTTTAGCCTAT
TCGACGACTTGTGAATTAGAAAGCAAAATTAATCGTCCAGTACTAGGCAG
CCTAAATATCTGTCCTAATAAGATTAATTCTGATCAAAACTTATTTTGGG
CTATATCAGCAATCAAACATGAAATTGTCCACATATTGGGCTTCAATGCT
GCATTGTATGCATTCTTTATGGATAACGATGGTATTCCTTTTACCCCAAG
AGATTCTCATGGATATCCAAATAACGGTTTTATTCAACTTGGTCTTTTAG
AATATTATAAATCCAGCGAGAGAGTAATAAAAGAAGAGAAATATAAAGCT
AAATACAAAGAAAGAACGGAAATTCAAACGCGTCATATTTTAGTCACTCC
AAATATTAAAAAAGAGGCGCAAGAACATTTCAATTGTTCAACTCTCGACG
GAATTTATCTTGAAGATTATGGAAATGCGAATTCGGTTTTGTCACATTTT
GAAAGAAGAATATTATATAACGAGCTAATGACAGCTACAATTCAAGATTA
TTCTTTTGTATCAAGGTTCACTATGGCATTTTTAGAAGATACTGGCTGGT
ATCAACCTGACTACCGGAAAGCAGACAAATTCCTTTTTGCCAAAAATGCT
GGTTGTGATTTTGTAATGAAAACTTGTTACGATTACATGCAGATCAAATC
GTCAAGGCTCCCGATTGAAAATCGAAATTCTATGAGGTCTTTGGTAACCC
AAAGGATTTGCGTGATTGACATCATCTAATAGCTAGTATGCAAGGACGGA
TCCAGGGAGGTGTGATGGGGCGATCGTTCAACTAAAAAGATCCCGAAGTT
ACTTTTTTGGTACTAAAATTAGTAAAAACATGAATCAATTGCTCCTTATT
GCAAAGCATTACCATATTCTGAAAATATGAAATGCTCAGATAATTTAGAA
TATAAAGAAGTTTGCAATCTGAGACAAGGATATCAAGTGCCTCCAAAATA
TAAATACTTCAAAGAAAACATGGGATCCTTTGATCACTTTGCAGAGTATT
GTCCTTACTATCAGAATTTTCGACAGTCGGAGAGCGACGGAACCATTTCT
AATGGCATTTGTACGGATCAAGGTAACAACGTTGTCAAAGGTTTTGATAA
AGGGTTAGAGACCTATGGATCATCATCAGCTTGCTTCGAATTCAAGAACG
TCAATATCCAAAGATGTGGAAACTCTCAATATTCTAGTGATGTGAGACCT
ATGTGCAAAAGATACGAATGTTCCTACATTCATAGATTACTTGTGTTAGT
AAACGGGTATAAATACCAATGCAGATATGATGGTGAGCATATCAAGACCA
ATTCCAGAACTAAATCCTTTATTTTCTCTGGGAAACTAAAGTGTCCAAAA
TGTTCTCTACTCTGTGATAACTCGATCTGCACTGCACCTTTTGTGACAGT
ATTTGACGGATGTGCCGATCCCAATGGCCAATGTTTTAATAATACTTCAT
TTGATATACAATGCTCGGGCTTTCAGATTAAAAACTTATTTTTATATAGT
TTTGTTTTACCTATTGTTGTCTTTTGG
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protein sequence of SMED30011562-orf-1

>SMED30011562-orf-1 ID=SMED30011562-orf-1|Name=SMED30011562-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=427bp
MILYFLVILLSGVIFISQSSFIPRSDVKITNIHLNSMHNKRIKRDVRNLR
ILIHYDKSFDSLGNKNEFKKNAIEPAVKFWEDSLIVKNPATSPILIERTC
PTGFRFAFVNGNRIKICKDKCLLDPKCSLAVIPEKYLAKCYYIDDIHYEL
YRTSGEDGAGAINADLIILVSYSSNGCSENSLAYSTTCELESKINRPVLG
SLNICPNKINSDQNLFWAISAIKHEIVHILGFNAALYAFFMDNDGIPFTP
RDSHGYPNNGFIQLGLLEYYKSSERVIKEEKYKAKYKERTEIQTRHILVT
PNIKKEAQEHFNCSTLDGIYLEDYGNANSVLSHFERRILYNELMTATIQD
YSFVSRFTMAFLEDTGWYQPDYRKADKFLFAKNAGCDFVMKTCYDYMQIK
SSRLPIENRNSMRSLVTQRICVIDII*
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protein sequence of SMED30011562-orf-2

>SMED30011562-orf-2 ID=SMED30011562-orf-2|Name=SMED30011562-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=217bp
MKCSDNLEYKEVCNLRQGYQVPPKYKYFKENMGSFDHFAEYCPYYQNFRQ
SESDGTISNGICTDQGNNVVKGFDKGLETYGSSSACFEFKNVNIQRCGNS
QYSSDVRPMCKRYECSYIHRLLVLVNGYKYQCRYDGEHIKTNSRTKSFIF
SGKLKCPKCSLLCDNSICTAPFVTVFDGCADPNGQCFNNTSFDIQCSGFQ
IKNLFLYSFVLPIVVFW
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0008233peptidase activity
GO:0008237metallopeptidase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
GO:0004222metalloendopeptidase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000018Category 4 cell
PLANA:0000026gut
PLANA:0002089reproductive organ
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001577Peptidase_M8
Vocabulary: biological process
TermDefinition
GO:0007155cell adhesion
GO:0006508proteolysis
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane