SMED30011561

Overview
NameSMED30011561
Smed IDSMED30011561
Length (bp)2063
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30011561 (SMED30011561) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30011561 (SMED30011561) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30011561 (SMED30011561) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30011561 (SMED30011561) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30011561

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30011561SMESG000066396.1 dd_Smed_v4_7890_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30011561SMESG000066396.1 dd_Smed_v4_7890_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30011561SMESG000066396.1 dd_Smed_v4_7890_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30011561SMESG000066396.1 dd_Smed_v4_7890_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30011561SMESG000066396.1 dd_Smed_v4_7890_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011561SMESG000066396.1 Contig38796newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30011561SMESG000066396.1 Contig38796uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SMED30011561 vs. TrEMBL
Match: G7YIX3 (Uncharacterized protein OS=Clonorchis sinensis OX=79923 GN=CLF_109072 PE=4 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.000e-10
Identity = 57/175 (32.57%), Postives = 84/175 (48.00%), Query Frame = 1 
Query:  808 LYVEKGRTIE--VTAKTNINISS----------NTVLKFDIFTMKGTNEEPVYGDINGHQSN----PNQNLCFIQAIEE--KTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCESSNV-LASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIP 1275
            L+ E+GR +E  ++ +   N SS          +  L+F  F   G+   PV G     Q      P+Q LCFIQ + +  + S  Y      F  M +        + ++FPFLN +CPT  +K V + +SV +S N  L  T+FQ+VCCTSP RD +R   ++ S   K   P
Sbjct:  247 LFAERGRVLETQISYRMATNRSSEHTDRRPLCQDIKLRFLPFNRCGSVVTPVLGFRGPMQKKAYNMPDQ-LCFIQLLGDNVQDSPNYATDSGGFHYMEIRMLDYCDIYQLVFPFLNSQCPTAYRKDVWIRVSVIDSKNKELCQTEFQVVCCTSPVRDCRRLLNRYPSTVKKAPHP 420
[Close]
BLAST of SMED30011561 vs. TrEMBL
Match: A0A419QEW8 (RNA-directed DNA polymerase from mobile element jockey OS=Clonorchis sinensis OX=79923 GN=pol PE=4 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.204e-9
Identity = 57/175 (32.57%), Postives = 84/175 (48.00%), Query Frame = 1 
Query:  808 LYVEKGRTIE--VTAKTNINISS----------NTVLKFDIFTMKGTNEEPVYGDINGHQSN----PNQNLCFIQAIEE--KTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCESSNV-LASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIP 1275
            L+ E+GR +E  ++ +   N SS          +  L+F  F   G+   PV G     Q      P+Q LCFIQ + +  + S  Y      F  M +        + ++FPFLN +CPT  +K V + +SV +S N  L  T+FQ+VCCTSP RD +R   ++ S   K   P
Sbjct:  247 LFAERGRVLETQISYRMATNRSSEHTDRRPLCQDIKLRFLPFNRCGSVVTPVLGFRGPMQKKAYNMPDQ-LCFIQLLGDNVQDSPNYATDSGGFHYMEIRMLDYCDIYQLVFPFLNSQCPTAYRKDVWIRVSVIDSKNKELCQTEFQVVCCTSPVRDCRRLLNRYPSTVKKAPHP 420
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BLAST of SMED30011561 vs. TrEMBL
Match: A0A4S2MKD1 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000308 PE=4 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.974e-9
Identity = 53/175 (30.29%), Postives = 79/175 (45.14%), Query Frame = 1 
Query:  808 LYVEKGRTIEVTAKTNIN------------ISSNTVLKFDIFTMKGTNEEPVYGDINGHQSN----PNQNLCFIQAIEE--KTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCESSNV-LASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIP 1275
            L+ E+GR +E      +             +  +  L+F  F   G+   PV G     Q      P+Q LCFIQ + +  + S  Y    + F  M +        + ++FPFLN +CPT  +K V + +SV    N  L  T+FQ+VCCTSP RD +R   ++ S   K   P
Sbjct:  247 LFAERGRVLETQISYRMATKRPSEHTDRRPLCQDIKLRFMPFNRCGSVVTPVLGFRGPMQKKAYNMPDQ-LCFIQLLADNVQDSPNYATDSSGFHYMEIRMLDYCDIYQLVFPFLNSQCPTAYRKDVWIRVSVINDKNKELCQTEFQVVCCTSPVRDCRRLLNRYPSTVKKAPHP 420
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BLAST of SMED30011561 vs. TrEMBL
Match: A0A183MHL1 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS15536 PE=4 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 3.482e-9
Identity = 43/127 (33.86%), Postives = 71/127 (55.91%), Query Frame = 1 
Query:  880 LKFDIFTMKGTNEEPVYGDINGHQSNPN-----QNLCFIQAIEEKTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVC-ESSNVLASTKFQLVCCTSPNRDMKRHFEK 1242
            L+F  FT+ G    P  G  N     PN     + LCFIQA++   +  Y    + ++ M + F      + ++FPFLN KCP+T KK V +++++  E+   L+ST+F++V C SP RD +R+ ++
Sbjct:  232 LRFKPFTIFGGICTPAIG-YNDPIQIPNILSKQEQLCFIQAVQNDNNVTYKLMNDGYLVMDIDFNNFCDIYHLVFPFLNSKCPSTWKKDVHITVTLIDENDKELSSTEFEVVSCASPIRDARRYQQR 357
[Close]
BLAST of SMED30011561 vs. TrEMBL
Match: A0A5J4NRK8 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0007158 PE=4 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.050e-8
Identity = 61/215 (28.37%), Postives = 96/215 (44.65%), Query Frame = 1 
Query:  646 NRTDNNIYPQSIYQNKEIWLNVGFATPNSFFYKDADKPSKAVTVTHLPNHNYAVLYVEKGRTIEVTA---------KTNINISSNTV-LKFDIFTMKGTNEEPVYGDINGHQSN---PNQNLCFIQAIEEK--TSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCE-SSNVLASTKFQLVCCTSPNRDMKRHFEK 1242
            N +D  I   S   N+   L V F    +   +   K  K   +  L +   + L+VE+GR +E              N ++  N   L+F  +T  G   +P  G  N  Q     P + LCF+Q  E +  T   Y    N ++ +     +    + ++FPF N +CPTT +K V + ISV + + + L ST FQ+V C +P RD KR  ++
Sbjct:  192 NHSDYLIDFSSACSNRTAQLQVTFLPAEANTEEKETKFGKVAKIAKLCD-GTSKLFVERGRLVETCVTLTEFSHLTDENASLRDNGYRLRFIPYTSFGGVCKPAIGYHNQIQKAHYVPTEQLCFVQLFEARLDTWHQYQTDGNGYLFLETVLTSRCGIYQLVFPFHNSQCPTTCRKDVHIRISVVQPNGSELCSTNFQVVSCATPLRDFKRFCQR 405
[Close]
BLAST of SMED30011561 vs. Planmine SMEST
Match: SMESG000066396.1 (SMESG000066396.1)

HSP 1 Score: 735.717 bits (1898), Expect = 0.000e+0
Identity = 360/362 (99.45%), Postives = 360/362 (99.45%), Query Frame = 1 
Query:  382 MNDDYFRKIDSDIIGQIKLPSFITFNPSSSQFTLGDYVPENFYIYQDINQYHPDFGQTYEDDSANQCSLPSNSSMSTPDVLQSFQPNPNRTDNNIYPQSIYQNKEIWLNVGFATPNSFFYKDADKPSKAVTVTHLPNHNYAVLYVEKGRTIEVTAKTNINISSNTVLKFDIFTMKGTNEEPVYGDINGHQSNPNQNLCFIQAIEEKTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCESSNVLASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIPSKREKIIIEGKSLQCEPVVNKHNENNEKINGNPQYVIMTENYEIWKILNIVHQQLMEHFDSNKK 1467
            MNDDYFRKIDSDIIGQIKLPSFITFNPSSSQFTLGDYVPENFYIYQDINQYHPDFGQTYEDDSANQCSLPSNSSMSTPDVLQSFQPN NRTDNNIYPQSIY NKEIWLNVGFATPNSFFYKDADKPSKAVTVTHLPNHNYAVLYVEKGRTIEVTAKTNINISSNTVLKFDIFTMKGTNEEPVYGDINGHQSNPNQNLCFIQAIEEKTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCESSNVLASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIPSKREKIIIEGKSLQCEPVVNKHNENNEKINGNPQYVIMTENYEIWKILNIVHQQLMEHFDSNKK
Sbjct:    1 MNDDYFRKIDSDIIGQIKLPSFITFNPSSSQFTLGDYVPENFYIYQDINQYHPDFGQTYEDDSANQCSLPSNSSMSTPDVLQSFQPNTNRTDNNIYPQSIYPNKEIWLNVGFATPNSFFYKDADKPSKAVTVTHLPNHNYAVLYVEKGRTIEVTAKTNINISSNTVLKFDIFTMKGTNEEPVYGDINGHQSNPNQNLCFIQAIEEKTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKLVLLSISVCESSNVLASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIPSKREKIIIEGKSLQCEPVVNKHNENNEKINGNPQYVIMTENYEIWKILNIVHQQLMEHFDSNKK 362
The following BLAST results are available for this feature:
BLAST of SMED30011561 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7YIX31.000e-1032.57Uncharacterized protein OS=Clonorchis sinensis OX=... [more]
A0A419QEW81.204e-932.57RNA-directed DNA polymerase from mobile element jo... [more]
A0A4S2MKD11.974e-930.29Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A183MHL13.482e-933.86Uncharacterized protein OS=Schistosoma margrebowie... [more]
A0A5J4NRK81.050e-828.37Uncharacterized protein OS=Paragonimus westermani ... [more]
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BLAST of SMED30011561 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30011561 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000066396.10.000e+099.45SMESG000066396.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011561 ID=SMED30011561|Name=SMED30011561|organism=Schmidtea mediterranea sexual|type=transcript|length=2063bp
TATCAACGTTCTAGAACACAAACAAAATGTATTGATTTTCAATTGTCGAT
ACAATGCGCAGCACAATGTGAACTACACGTGTCACCGAGTGTGCAAAAGT
GCTTGTGCATATCTGTGTTTGTGAATAAAATTTTAGTTTCACTTTACATA
GACCTTTCATAGTTTTCGCGACCACGCAAATCTGTCAAGTTCAATAATCA
ATATTCACAGTGTTTATCAACTATTTGATGACAATTCTTCAGATTTAAAT
TTGGAAATTCCTGCGACAATTATTTTGGCATTTATTGATTTCAAATTTAT
AAACAGCATTTATTTAGTGCCGATCAGCATTTATTAAGAGCATTTATTGG
ATTTATTGACTGATGTATTGATAGCAGAACCATGAACGATGATTATTTTA
GAAAAATTGATTCTGATATAATCGGACAGATCAAATTGCCAAGTTTCATT
ACCTTCAACCCATCGTCAAGCCAGTTCACACTTGGGGATTATGTCCCTGA
AAATTTCTACATTTATCAGGACATTAATCAATATCATCCAGATTTTGGTC
AAACATATGAAGACGACTCAGCAAATCAGTGTTCGCTGCCGTCAAATTCA
TCAATGTCCACGCCTGATGTCCTGCAAAGTTTTCAACCGAACCCTAATAG
AACTGATAATAATATTTATCCACAAAGCATTTATCAAAATAAAGAAATAT
GGCTAAATGTCGGATTTGCTACTCCTAATTCATTTTTCTACAAAGATGCT
GACAAACCGTCTAAAGCAGTTACGGTAACGCATTTACCAAATCATAATTA
TGCCGTACTATATGTGGAAAAAGGTCGAACAATTGAAGTAACAGCTAAAA
CAAACATAAATATTTCATCTAATACTGTTTTGAAATTTGATATTTTTACA
ATGAAAGGAACTAACGAAGAACCAGTTTATGGGGATATCAATGGGCATCA
ATCTAATCCGAATCAAAATTTGTGTTTTATCCAAGCGATTGAAGAAAAAA
CGTCGGCTATTTATGTGAAATCGGAAAATAATTTCATTTCTATGCTGGTT
CCGTTCAAAACTAATCCGTCTAGTTTTTCTGTAATATTTCCGTTTTTGAA
TTTTAAATGTCCTACGACTTCTAAGAAACTCGTGCTATTGAGCATATCAG
TTTGTGAATCCTCGAACGTTTTAGCATCAACAAAATTTCAATTGGTTTGT
TGTACATCTCCAAATAGAGATATGAAAAGACATTTTGAAAAGTTTACTTC
AAAGCCGTCGAAAAATAAAATTCCATCGAAAAGAGAAAAAATAATTATTG
AAGGGAAATCTTTACAATGTGAACCTGTGGTCAATAAACATAATGAAAAT
AATGAAAAGATAAATGGAAATCCTCAATATGTTATTATGACTGAAAATTA
TGAAATCTGGAAAATTCTAAATATCGTTCATCAACAGTTAATGGAGCATT
TTGACTCCAATAAAAAATGAAGTTTAACTATTATTATCATGAAATAACTA
AAGAAAAATTTTTACAAAAAAATCATTTGAAGCCCTTTGTGACTTTTGAA
ACGTTTGATTGAGCATTTGAGTTTAAATTAAAAATTTAACTTTTACAATT
CAACAATTTTGAGAGAAAAAAAAACATTTTTTGATTGAAAGGATTTTATC
ATTCGGTTCTGTGGTAAATTCACCTAGCATTTCATTTTGATAATTTTGCA
GTTAGAGATTATTTTATTTAATTTCGAGTAAATCTATCCAGGCATTATAT
GTTTCTGTATAATTTATCATAGCATTTTTAGAGGCTTTTGCTGTTATCGT
GGTATAATTCTATGAGGTTTTCAATGATTTTCAGATTTACAAAGATAATT
TTGCATTTCCTTCACCAATTTCAATGTGATTTTAGTTCTCTACTGTTTAT
TATTTAAATTTATATTTTTTTTGTTTATTATTGTGAAAATCGGATATTGT
TGATTATTTTTGTAAGTTAAATAATTGTTGTGTCATTGCTGATTGGAAAA
CGCCTTTTTCGCATTTTACTATTGGATTTATCAAGATTATTATTGTTATA
AGAATATGTTTAC
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protein sequence of SMED30011561-orf-1

>SMED30011561-orf-1 ID=SMED30011561-orf-1|Name=SMED30011561-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=363bp
MNDDYFRKIDSDIIGQIKLPSFITFNPSSSQFTLGDYVPENFYIYQDINQ
YHPDFGQTYEDDSANQCSLPSNSSMSTPDVLQSFQPNPNRTDNNIYPQSI
YQNKEIWLNVGFATPNSFFYKDADKPSKAVTVTHLPNHNYAVLYVEKGRT
IEVTAKTNINISSNTVLKFDIFTMKGTNEEPVYGDINGHQSNPNQNLCFI
QAIEEKTSAIYVKSENNFISMLVPFKTNPSSFSVIFPFLNFKCPTTSKKL
VLLSISVCESSNVLASTKFQLVCCTSPNRDMKRHFEKFTSKPSKNKIPSK
REKIIIEGKSLQCEPVVNKHNENNEKINGNPQYVIMTENYEIWKILNIVH
QQLMEHFDSNKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR011615p53_DNA-bd
IPR012346p53/RUNT-type_TF_DNA-bd_sf
Vocabulary: molecular function
TermDefinition
GO:0044212transcription regulatory region DNA binding
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0003677DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR011615p53, DNA-binding domainPFAMPF00870P53coord: 138..284
e-value: 1.2E-7
score: 31.7
IPR012346p53/RUNT-type transcription factor, DNA-binding domain superfamilyGENE3DG3DSA:2.60.40.720coord: 112..295
e-value: 2.6E-6
score: 29.4