Minichromosome maintenance 9 homologous recombination repair factor

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDM----GVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ IF+S   +   + L  +     V++ +   N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F +  +F +    +T   P  C +  S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN IQ VN+  S+   +  E++ +F+ FWE Y    F  RN++++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E  +++EK+K+YF  IR+   P ++   + +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V+VMES++ G  +L     L ++FP +P E+Y+     I +KL+++S +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQ---NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQY---YTFCRPSSCPSLES-CDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQ-VNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRN-LQPTLSDVGNQVLLRYYQMQRQSDCRNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPENPGEQYQRQCELILEKLELQSLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDM----GVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ IF+S   +   + L  +     V++ +   N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F +  +F +    +T   P  C +  S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN IQ VN+  S+   +  E++ +F+ FWE Y    F  RN++++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E  +++EK+K+YF  IR+   P ++   + +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V+VMES++ G  +L     L ++FP +P E+Y+     I +KL+++S +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQ---NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQY---YTFCRPSSCPSLES-CDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQ-VNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRN-LQPTLSDVGNQVLLRYYQMQRQSDCRNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPENPGEQYQRQCELILEKLELQSLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDM----GVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGL 1247
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ IF+S   +   + L  +     V++ +   N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F +  +F +    +T   P  C +  S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN IQ VN+  S+   +  E++ +F+ FWE Y    F  RN++++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AG+
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQ---NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQY---YTFCRPSSCPSLES-CDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQ-VNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGI 385          

Query:   81 IEGRHYFLNILTDYLSKNHIQDIQNIINASFKKSINEC-----ETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQT--FESSKESFNL---------------------EKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            +E  H F N L  ++  +H  ++       FK+ I++      E+LV+  + +   +    ++ +L     +L++IF+    +++ +    M     +   +  VRI+ LP  +E+      + + + + +  +  V     +       +Y C KC F V+  F +S        P  C    S   +  F++     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + G     ++      N   V   VILAN +   ++ ++       ++K+   L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K++ R++ TTG G++  GLT    +   S  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+VIAA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++        S+KE   L                     E LK Y  Y +   HPK+       + K Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V E+D  MA+ VM
Sbjct:  193 LEIHHRFKNFLRTHVD-SHGHNV-------FKERISDMCKENRESLVVNYEDLAAREHV--LAYFLPEAPAELLQIFDEAALEVVLA----MYPKYDRITNHIHVRISHLPLVEELRSL---RQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNF-VLGPFCQSQNQEV--KPGSCPECQS---AGPFEV----NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEK------IFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798          

Query: 1008 LLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQT--FESSKESFNL---------------------EKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            ++ + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K++ R++ TTG G++  GLT    +   S  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+VIAA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++        S+KE   L                     E LK Y  Y +   HPK+       + K Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V E+D  MA+ VM
Sbjct:  408 MIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 730          

Query:  375 QVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDI-VESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDEC--VIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLC-GSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFIL-NHQTFESS-----KESFNLEK----------------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            +VRI+ LP  ++I    + + V +   +  A  V  A  I       +Y C  C + +     ++D       P  C +         F++ VE++        N Q I +QE    ++ G +PR+  VIL  DL D  KPGD++ + G     ++      +   V   +I AN I   +   S+  + +     D +   E     + + R  + S + P IYG   +K A+AL L  G         ++RG+ ++L+ GDPGTAKSQFL++A  + PRSVLTTG G++  GLT    +   +  W+LEAGA+VLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L  RC+VIAA+NP  G Y+ T++   N  +  P+LSRFD++ ++ D+ +   D  ++ F++ NH+T         KE   LE+                L+ Y  Y R   HP +  + S      +  MRK  +      IT+R +ES+IRLS++HA+  +R +V +ED   A+ VM
Sbjct:  258 KVRISQLPVEEDIR---MLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFVQQNDEEVR---PTICPSCQG---KGPFELNVENT-----VYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNFDGSLNYKQGFPVFNTLIHANHITNKDKMASDQLTDE-----DIKAIRELSQDPNISQR--VFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVKEGDELEEDQMDERTGVRLIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVM 772          

Query:  375 QVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDI-VESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDEC--VIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLC-GSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFIL-NHQTFESS-----KESFNLEK----------------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            +VRI+ LP  ++I    + + V +   +  A  V  A  I       +Y C  C + +     ++D       P  C +         F++ VE++        N Q I +QE    ++ G +PR+  VIL  DL D  KPGD++ + G     ++      +   V   +I AN I   +   S+  + +     D +   E     + + R  + S + P IYG   +K A+AL L  G         ++RG+ ++L+ GDPGTAKSQFL++A  + PRSVLTTG G++  GLT    +   +  W+LEAGA+VLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L  RC+VIAA+NP  G Y+ T++   N  +  P+LSRFD++ ++ D+ +   D  ++ F++ NH+T         KE   LE+                L+ Y  Y R   HP +  + S      +  MRK  +      IT+R +ES+IRLS++HA+  +R +V +ED   A+ VM
Sbjct:  258 KVRISQLPVEEDIR---MLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFVQQNDEEVR---PTICPSCQG---KGPFELNVENT-----VYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDSCKPGDEIEVTGVYTNNFDGSLNYKQGFPVFNTLIHANHITNKDKMASDQLTDE-----DIKAIRELSQDPNISQR--VFSSIAPSIYGHDDVKRAIALALFRGEAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPDAKKIVKEGDELEEDQMDERTGVRLIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQMRKESMATGSVAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVM 772          

Query:  432 KSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKL-SPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIR-RWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-HQTF----ESSKESFNLEKLKSYFAYIRSTFHPKMTPE-ASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVME 1898
            K+ ++G  +S+   V+RA  ++       Y C  C      E  +        PP  C N    CV +  +     +L   KF +  QE+ +QE  + +  G +PRT+ V +  ++      G+ V ++G  +    +  R     V    + A+ I    + + +N +       + ++   K  G ++     L + + P I+G   +K  L + L G  +   NGMK+RG  ++L++GDPG AKSQ L + ++L PRS  TTG GS+  GLT   +K+  +G  SLE GALVLADGGICCIDEF  + + D+ AIHE MEQQ+IS+AKAGI+  L  R ++IAA NP  G Y+  +SI  N  + + LLSRFDLI L+ D  +   D  +++ I   HQ         K+  +LE L+ Y +  + T+ P + P     I+E Y    R +  ++    ++ R +  ++R++ + A+  +   V E D   A+ +M+
Sbjct:  166 KATEIGHLVSMKGVVIRATEVKPCVEVMTYTCDTCA----AEVYQPVKGMQFTPPVNCPNKE--CVEAKANGRLHMQLRGSKFVK-FQELKIQELSEQVPVGSIPRTMTVHVYGEMTRKCNTGNVVHVSGVFLPIMQSGFRPTGGLVADTYLEAHYI----NNLDDNPTFNGVQSAELEVLRRK--GDNYET---LAASIAPEIFGHVDVKKCLLMALVGGNDNSSNGMKIRGCINVLMMGDPGVAKSQLLGYVNRLAPRSQYTTGRGSSGVGLTAAVMKDPVTGEMSLEGGALVLADGGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAGIMTTLNARTAIIAAANPAYGRYNPNRSIEQNVDLPAALLSRFDLILLMQDKADRENDKILAEHITYVHQHGCHPNREKKDLISLETLREYISLCK-TYTPTVDPALRERIVEAYVEMRRDARYSSDPTFVSPRMILGIVRMATARAKLRLSTIVDESDVEEALRLMQ 648          

Query: 1107 GMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFIL-NHQTFESSKES---FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLD---RITMRFLESLIRLSQSHARF 1841
            G  +RG+ ++ +VGDP TAKSQ LK   + +PR++ T+G  S+ AGLT   VK  ES  + +EAGAL+LAD G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAG+   L  R S++AA NP  G YD ++ +  N  +++P++SRFDL F+L+D CNE  D  ++  IL NH+      E    + ++ +K Y A+ R  F PK++ +A+  L + Y  +R S+  N+     RIT+R LESL+RLS++ AR 
Sbjct:   90 GTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDLFFVLVDECNEVTDYAIARRILDNHRAISEHTERDSVYKIDDIKKYIAFAR-CFKPKISDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARL 343          

Query:  444 VGKFLSVAATVVRAGSIQVLEFQRE-YICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI-----------------RRWNNLRVND--------------ECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKS-FTARNL---------LISQMCPLIYGMY--FLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFIL-NHQTFESSKES---FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLD---RITMRFLESLIRLSQSHARF 1841
            VG  + +A  +VR   +   E  R  ++C+ C  +      +    F    P  C+N    C++ + F +  +S     F    Q+I +QE    L  G +PRT+ VI+  ++V+ V+PGD   I GT+I                    N  R  D              +   ++  LA  IQ     +  + S   E + D+   W K   +   T + +         ++  + P IYG +   L + L L+   ++     G  +RG+ ++ +VGDP TAKSQ LK   + +PR++ T+G  S+ AGLT   VK  ES  + +EAGAL+LAD G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAG+   L  R S++AA NP  G YD ++ +  N  +++P++SRFDL F+L+D CNE  D  ++  IL NH+      E    + ++ +K Y A+ R  F PK++ +A+  L + Y  +R S+  N+     RIT+R LESL+RLS++ AR 
Sbjct:  130 VGGLVRIAGQIVRTHPVHP-ELSRACFVCEDCGVTT----RDVQQQFRYTQPTKCAN--PQCMNRTRFSLDVNSSTFVDF----QKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAVE-ETDYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVAKKSRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDLFFVLVDECNEVTDYAIARRILDNHRAISEHTERDSVYKIDDIKKYIAFAR-CFKPKISDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARL 637          

Query:  249 ISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDEC--VIQLVILANEI------QIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCF-FNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-HQTFESSK--------------ESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAF 1955
            ++ +L     ++++IF+   AK +  S+      +  EI    VRI+ LP  +E+ RT   + + + + +     V     +       +Y C KC + V+  F +S  +  I P       S+G  S          +     RN Q+I +QE    +  G +PR+  VIL  DL D  KPGD++ + G     ++     D+   V   VI+AN +      Q+V      + +   ++  D ++               +++ M P IYG  ++K ALAL L G E+       KVRG+ ++LI GDPGTAKSQFLK+  K+ PR+V TTG G++  GLT    +   S  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+VIAA NP  G YD + + + N  ++ P+LSRFD++ ++ D  +   D  ++ F+++ H     S+              +    + L+ Y  Y +    PK+T      + K Y  +R+         IT+R +ES+IR+S++HAR  +RE V E D  MA+ +M  +   +   S  +++ S F
Sbjct:  229 LAYFLPEAPFQMLEIFDK-VAKDMVLSIFPTYERVTTEI---HVRISELPLIEEL-RTF--RKLHLNQLVRTLGVVTATTGVLPQLSVIKYDCVKCGY-VLGPFVQSQNT-EIKPGSCPECQSTGPFSI--------NMEQTLYRNYQKITLQESPGRIPAGRIPRSKDVILLADLCDQCKPGDELEVTGIYTNNYDGSLNTDQGFPVFATVIIANHVVVKDSKQVVQSLTDEDIATIQKLSKDPRIVER------------VVASMAPSIYGHDYIKRALALALFGGESKNPGEKHKVRGDINLLICGDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGLTAYVRRNPVSREWTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSMTFSENVNLSEPILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHMKHHPSEEEQPELEEPQLKTVDEIPQDLLRQYIVYAKENIRPKLTNIDEDKIAKMYAQLRQESFATGSLPITVRHIESVIRMSEAHARMHLRENVMEADVSMAIRMMLESFIEAQKFSVMKKMRSTF 795          

Query:  369 NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSN-YSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI-------------RRWNNLRVN----------------DECVIQLVILANEIQIVNHTISNNYSIKSEM---KLDFQLF---WEKYHGKSFTARNL---LISQMCPLIYGMYFLKLALALV-LCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-HQTFESSKE-SFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLD---RITMRFLESLIRLSQSHARF 1841
            +C V  T +P   ++   +  K   +G  + ++  VVR   +        ++C  C+     E    +  F    P  C N   S       D+ +S  L      + Q+I +QE    L  GC+PR +++IL  +LV+ V+ GD     GT+I             R  N+ R                   E   ++  LA  +Q             SE+    +  Q+    W K +  S   RNL   LIS + P IYG   +K  + L    G          +RG+ ++ IVGDP TAKSQFLK     +PR++ T+G  S+ AGLT   V+  ES  + +EAGAL+LAD GICCIDEF  + + D+VAIHEAMEQQ+IS+A+AG+   L  R S++AA NP  G YD ++S+  N  +++P++SRFDL F+L+D CNE  D  ++  I++ H   E S E ++  E++  Y  + R  F P ++ EA  +L + Y  +R+ +   S     RIT+R LES+IRLS++ A+ 
Sbjct:  103 DCYVAFTEVPTRHKVRDLTTSK---IGTLIRISGQVVRTHPVHPELVSGVFMCLDCQ----TEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKSLFL------DFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMSEVTAEDMKKQMTDAEWHKIYEMS-KDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQ-FKPVISQEAGHMLVENYGHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKL 626          

Query: 1011 LISQMCPLIYGMYFLKLALA-LVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-------HQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRK--SEITNSLDR-----ITMRFLESLIRLSQSHARFMMREFVKEEDA-----VMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEE-YRLLKLNIFKKLQIKSFIPPNNPGIVQD 2060
            L   + P I+G   +K A+  ++  GS     +G+  RG+ ++L++GDPGTAKSQ LKF  K+ P +V T+G GS+ AGLT + +K+  +  + +E GA+VLADGG+ CIDEF  +RE D+VAIHEAMEQQ+IS+AKAGI   L +RCSV+AA N   G +D T+    N      +LSRFD+IF++ D  +ES D  ++  I+N           E ++   +L   K Y  Y R+   P+++  A   L+  Y  MR    +   + D+     IT+R LE++IR+S+S A+  ++ F  +E       +  V+ +++ + GS   +        F T+ ++E    ++  + ++  I S +   N  I+QD
Sbjct:  332 LSQSLAPSIFGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGRWDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTLDAAMTGSLAGA------EGFTTEEDQETLNRIEKQLKRRFAIGSQVSEQN--ILQD 696          

Query:  681 RNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLA-LALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLT--VTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-HQ----------------------TFESSKESFNLEKLKSYFA-----------------YIRSTFH------PKMTPEASVILEKYYTWMRKSE-ITNSLDR---ITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQ 1937
            ++ Q + +QE  +    G +PR++ ++ DDDLVD  KPGD V I G+                + V+LAN I +++    +N  I  E      +   K   K+     LL   + P I+G  ++K A L L+L G E    NG ++RG+ ++L++GDP  AKSQ L++     PR++ TTG GS+  GLT  VT  +E+G   LEAGA+VLAD G+ CIDEF  + + D+ AIHE MEQ  ++++KAGI   L  RCSV+AA NP  G YD  ++   N  +   LLSRFDL+F++LD  +   D  +SD ++  H+                      +F SS E  + E  + Y A                 ++R   H      PK+  +A   +   Y+ +R  E +   + R   IT R LE+LIRLS +HAR  M + V  +DA  A+ +++   Y   VL  D+
Sbjct:  191 KDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANNISLLSK--ESNLDISRE-----DIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQ-FAYFKKVLDKDR 655          

Query:  681 RNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLA-LALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLT--VTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFE------------------------SSKESFNLEKLKSYFA-----------------YIRSTFH------PKMTPEASVILEKYYTWMRKSE-ITNSLDR---ITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQ 1937
            ++ Q + +QE  +    G +PR++ ++ DDDLVD  KPGD V I G+                + V+LAN I +++    +N  I  E      +   K   K+     LL   + P I+G  ++K A L L+L G E    NG ++RG+ ++L++GDP  AKSQ L++     PR++ TTG GS+  GLT  VT  +E+G   LEAGA+VLAD G+ CIDEF  + + D+ AIHE MEQ  ++++KAGI   L  RCSV+AA NP  G YD  ++   N  +   LLSRFDL+F++LD  +   D  +SD ++    +                         SS+E  + E  + Y A                 ++R   H      PK+  +A   +   Y+ +R  E +   + R   IT R LE+LIRLS +HAR  M + V  +DA  A+ +++   Y   VL  D+
Sbjct:  191 KDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANNISLLSK--ESNLDISRE-----DIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQ-FAYFKKVLDKDR 656          

Query:  369 NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES---FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYR 1982
            N  VRI+ LP C E++R  IPK+ DVG FLSV  TV+R    +VLE++R+Y+C KC+  FSV   F +    +T  PP  C +   GC S  F  +  S   P  C++ QEI +QEQ++ LS G +PR++ +IL+DDLVD  K GDD+ + G V +RW  +  +  C +++V+ AN I+ VN+  S    +  +++ +F+ FW+ +       RN ++  +CP ++GMY +KLA+A+VL G  +    +G KVRGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGSTNAGLTV AVK+SG W LEAGALVL+DGG+CCIDEF SI+E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD   S++ N A+ASPLLSRFDL+ +LLD  N  WD  +S FIL ++   S  ES   +++EK+++YF  I+ T  P++TPEA+ IL +YY   R+S+  N+  R T+R LESL RL+++HAR M RE V  EDAV+ V+VME ++ G  +L     L ++FP +P E+Y+
Sbjct:  101 NMHVRISGLPVCPELTRDHIPKARDVGHFLSVTGTVIRTSVTKVLEYERDYMCNKCRHVFSVQASFEQF---YTFTPPTSCPS-EEGCGSFKFTCLSGSDAPPAACKDYQEIKIQEQVQKLSVGSIPRSMLIILEDDLVDSCKSGDDITVYGVVCQRWKPMFQDCRCDVEIVLKANYIE-VNNEQSTTALVLEDIQKEFEEFWDSHKHDPIAGRNEILMSLCPQVFGMYVVKLAVAMVLAGGVQRIDASGTKVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTNAGLTVAAVKDSGEWHLEAGALVLSDGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGMVCKLDTRTTILAATNPKGQYDPNVSVSVNVALASPLLSRFDLVLVLLDTKNPDWDKIISSFILQNKGAPS--ESLCLWSMEKMRAYFCLIK-TLKPRITPEANTILSRYYQLQRQSDSRNAA-RTTIRMLESLSRLAEAHARLMFRETVTVEDAVVVVSVMECSMQGGALLGNVNALHTSFPDEPCEQYK 635          

Query:  249 ISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWN---NLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSKE-------------SFNL-----EKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            ++ +L     +++KIF+   AK +  ++      +  EI    VRI +LP  +E+      + + + + +  +  V     +       +Y C KC F ++  F +S        P  C      C S   F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD+ KPGD++ + G     ++   N+  N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IY    +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   S  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+VIAA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++    +   S+KE             +F++     E L+ Y  Y +    PK+       + + Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V E+D  MA+ VM
Sbjct:  232 LAYFLPEAPAEMLKIFDEA-AKEVVLAMYPKYDRIAHEI---HVRIGNLPLVEELRSL---RQLHLNQLIRTSGVVTSCTGVLPQLGMVKYNCNKCNF-ILGPFFQSQNQEV--KPGSCPE----CQSLGPFEI----NMEQTVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDMCKPGDEIELTGIYHNNYDGSLNM-ANGFPVFATVILANHIARKDEGVAVAELTDEDVKAIVALSKDERIGER------IFASIGPSIYAHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSNKEGGVAGLEEVVLPNTFDVPPIPQELLRKYIIYAKERVRPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVLEDDVNMAIRVM 783          

Query:  447 GKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQI--KYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI---RRWNNLRVNDECVIQLVILANEIQ------------------IVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFF---NGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGG--WSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQ----------------TFESS--------------------KESFN---LEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV 1907
            GKF+ +  TVVR  +I+ L  +  ++C  C  +        D  +T+  P  C    S C   +F    SS  +     + Q I VQE +       G +PRTI+  L  DLVD   PGD V I G +       +     D+C+  L I AN +                    V  +I + Y+I+ E++    LF             L+++ +CP+IYG   +K  LAL L G    +    N + +RG+ HMLIVGDPG  KSQ L+    + PR V   G  +T +GLTV+  ++SG   ++LEAGALVL D GICCIDEF  +    + A+ EAMEQQSIS+AKAGIVC L  R S+IAA NP  G+Y+  ++++ N  + S LLSRFDL+F+LLD  NE  D  +S+ ++  +                T ESS                     E+F+    + L+ Y  Y R   HP ++ EA+ +L+ +Y  +RK   T     IT R LESLIRL+++ AR  +RE   + DA   V +M+ ++
Sbjct:  228 GKFVVIRGTVVRVSNIKPLCMKLAFVCNSCGDTQSVTLP--DGKYTM--PTKC--LQSECRGRSFTPNRSSPFT--LTVDWQTIKVQELMSGDQRESGRIPRTIECELTQDLVDSCVPGDMVTITGVIKVSNEEGSTRNKKDKCMFLLYIQANSVSNSKGQKSKAVSESEGQGPSVEFSIKDLYAIQ-EIQAQEDLF------------KLIVNSLCPVIYGHLLVKAGLALALFGGCQKYVDDKNRIPIRGDPHMLIVGDPGLGKSQMLQAVCNVAPRGVYVCGNTTTTSGLTVSLSRDSGSGDYALEAGALVLGDQGICCIDEFDKMGSQHQ-ALLEAMEQQSISLAKAGIVCTLPARTSIIAAANPVGGHYNKGKTVSENLKMGSALLSRFDLVFILLDTPNEDHDHLLSEHVMAMRAGKSGAVSGAAATRFNTHESSISILEVSSEKPLADTLKLVPGEAFDPIPHQLLRKYVGYARHYVHPTLSAEAAQVLQDFYLELRKQNQTADSTPITTRQLESLIRLTEARARVELREKATQSDAEDVVEIMKHSL 760          

Query:  435 SVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI-------------RRWNNLRVND------------------ECVIQLVILANEIQIVNHTISNNY---------SIKSEMKLDFQLFWEKYHGKSFTARNL---LISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFI--LNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSE---ITNSLDRITMRFLESLIRLSQSHARF 1841
            +V +G  L ++  VVR   +        ++C  C+ SVI +  +    F    P  C N    C +    +++++K   +F  + Q++ +QE    L  G +PR+++VIL  + V+  + GD     GT+I             R   + RV                    E   +L  LAN +   N                S+K++M +   L WEK    S   +NL   L + + P I+G   +K  + L+L G        G  +RG+ ++ IVGDP T+KSQFLK      PR+V T+G  S+ AGLT   VK  ES  + +EAGAL+LAD G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAG+   L  R S++AA NP  G Y+  +S+  N  +++P++SRFDL F+L+D CNE  D  ++  I  L+ +  ES +  ++ ++++ Y  + R  F PK+T EA   +   Y  +R+ +    T S  RIT+R LES++RLS+  AR 
Sbjct:  122 TVRIGTLLRISGQVVRTHPVHPELVSGTFLCLDCQ-SVIKDVEQQ---FKYTQPTICKN--PVCANRRRFMLDTNK--SRFV-DFQKVRIQETQAELPRGSIPRSVEVILRAEAVETAQAGDRCDFTGTLIVVPDVSAMALAGTRAETSSRVTGKEGFEADGIQGLKALGVRELSYRLAFLANYVAPTNPRFGGKELRQEDQTAESVKNQMTV---LEWEKVFEMS-QDKNLYHNLCTSLFPTIHGNDEIKRGILLMLFGGVAKTTMEGTSLRGDINVCIVGDPSTSKSQFLKHVEDFAPRAVYTSGKASSAAGLTAAVVKDEESHEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPIDGRYNRAKSLKQNVNMSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHARNVESVERVYSTDEIQRYILFARQ-FQPKITVEAQEFVVDQYKRLRQRDGGGTTKSAWRITVRQLESMLRLSEGMARL 628          

Query:  435 SVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI-------------RRWNNLRVND------------------ECVIQLVILANEIQIVNHTISNNY---------SIKSEMKLDFQLFWEKYHGKSFTARNL---LISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFI--LNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSE---ITNSLDRITMRFLESLIRLSQSHARF 1841
            +V +G  L ++  VVR   +        ++C  C+ SVI +  +    F    P  C N    C +    +++++K   +F  + Q++ +QE    L  G +PR+++VIL  + V+  + GD     GT+I             R   + RV                    E   +L  LAN +   N                S+K++M +     WEK    S   +NL   L + + P I+G   +K  + L+L G        G  +RG+ ++ IVGDP T+KSQFLK      PR+V T+G  S+ AGLT   VK  ES  + +EAGAL+LAD G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAG+   L  R S++AA NP  G Y+  +S+  N  +++P++SRFDL F+L+D CNE  D  ++  I  L+ +  ES +  ++ ++++ Y  + R  F PK+T EA   +   Y  +R+ +    T S  RIT+R LES++RLS+  AR 
Sbjct:  122 TVRIGTLLRISGQVVRTHPVHPELVSGTFLCLDCQ-SVIKDVEQQ---FKYTQPTICKN--PVCANRRRFMLDTNK--SRFV-DFQKVRIQETQAELPRGSIPRSVEVILRAEAVETAQAGDRCDFTGTLIVVPDVSAMALAGTRAETSSRVTGKEGFEADGIQGLKALGVRELSYRLAFLANYVAPTNPRFGGKELRQEDQTAESVKNQMTVQE---WEKVFEMS-QDKNLYHNLCTSLFPTIHGNDEIKRGILLMLFGGVAKTTMEGTSLRGDINVCIVGDPSTSKSQFLKHVEDFAPRAVYTSGKASSAAGLTAAVVKDEESHEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPIDGRYNRAKSLKQNVNMSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHARNVESVERVYSTDEIQRYILFARQ-FQPKITVEAQEFVVDQYKRLRQRDGGGTTKSAWRITVRQLESMLRLSEGMARL 628          

Query:  108 ILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCS---SLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTF-ESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
            +   ++ ++H ++I  I+   ++ +        L ++ M L +    I  Y      +++ IF++   +   S   S ++    + K+  N   RIT LP C E++R  IP++ DVG FLSV  TV+R   ++VLE++++++C KCK  V  + ++ +  +T  PP  CSN   GC SS F  +  S  +P  CR+ QEI +QEQ++ LS G +PR++ V+L+DDLVD  K GDDV + G V++RW  L ++  C +++V+ AN I  VN+       I  E++ +++ FWEKY       RN +++ +CP ++GM+ +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGST+AGLTVTAVK+SG W+LEAGALVLADGG+CCIDEF SI+E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +SI+ N A+ASPLLSRFDL+ +LLD  NE WD  +S FIL  +     S + +++EK+K+YF  I++   PKM+ +A+VIL +YY   R+S   N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V++MES++ G  +L     L ++FP +P E+YR+    + ++L ++  +
Sbjct:   14 VFESFVLEHHQKEIAQILTEKYEDA-----HYSLVVNAMTLFEANMEIGEYFNAFPNEVLPIFDNALRRAAMSFLQSCSEKQTLVMKQ--NFHARITGLPVCPELTREHIPRTRDVGHFLSVTGTVIRTSLVKVLEYEQDFMCNKCKHVVTVK-ADFEQYYTFKPPITCSN-EEGCNSSKFTCLSDSS-TPASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLVDSCKSGDDVTVYGVVMQRWKPLYIDTRCDLEIVLKANYI-AVNNEQPCGVVINEEVRKEYEGFWEKYRNSPLEGRNEILASLCPQVFGMFVVKLAVAMVLAGGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKDSGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPEESISVNVALASPLLSRFDLVLVLLDTKNEDWDRIISSFILESKGCPRKSDKLWSMEKMKTYFCLIKN-LQPKMSQDANVILVRYYQLQRQSSCRNAA-RTTIRLLESLIRLAEAHARLMYRDVVTTEDAITVVSIMESSMQGGALLGGVNALHTSFPENPREQYRMQCELLLERLGLQKLL 646          

Query:  108 ILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCS---SLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTF-ESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
            +   ++ ++H ++I  I+   ++ +        L ++ M L +    I  Y      +++ IF++   +   S   S ++    + K+  N   RIT LP C E++R  IP++ DVG FLSV  TV+R   ++VLE++++++C KCK  V  + ++ +  +T  PP  CSN   GC SS F  +  S  +P  CR+ QEI +QEQ++ LS G +PR++ V+L+DDLVD  K GDDV + G V++RW  L ++  C +++V+ AN I  VN+       I  E++ +++ FWEKY       RN +++ +CP ++GM+ +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGST+AGLTVTAVK+SG W+LEAGALVLADGG+CCIDEF SI+E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +SI+ N A+ASPLLSRFDL+ +LLD  NE WD  +S FIL  +     S + +++EK+K+YF  I++   PKM+ +A+VIL +YY   R+S   N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V++MES++ G  +L     L ++FP +P E+YR+    + ++L ++  +
Sbjct:   11 VFESFVLEHHQKEIAQILTEKYEDA-----HYSLVVNAMTLFEANMEIGEYFNAFPNEVLPIFDNALRRAAMSFLQSCSEKQTLVMKQ--NFHARITGLPVCPELTREHIPRTRDVGHFLSVTGTVIRTSLVKVLEYEQDFMCNKCKHVVTVK-ADFEQYYTFKPPITCSN-EEGCNSSKFTCLSDSS-TPASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLVDSCKSGDDVTVYGVVMQRWKPLYIDTRCDLEIVLKANYI-AVNNEQPCGVVINEEVRKEYEGFWEKYRNSPLEGRNEILASLCPQVFGMFVVKLAVAMVLAGGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKDSGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPEESISVNVALASPLLSRFDLVLVLLDTKNEDWDRIISSFILESKGCPRKSDKLWSMEKMKTYFCLIKN-LQPKMSQDANVILVRYYQLQRQSSCRNAA-RTTIRLLESLIRLAEAHARLMYRDVVTTEDAITVVSIMESSMQGGALLGGVNALHTSFPENPREQYRMQCELLLERLGLQKLL 643          

Query:  108 ILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCS---SLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTF-ESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
            +   ++ ++H ++I  I+   ++ +        L ++ M L +    I  Y      +++ IF++   +   S   S ++    + K+  N   RIT LP C E++R  IP++ DVG FLSV  TV+R   ++VLE++++++C KCK  V  + ++ +  +T  PP  CSN   GC SS F  +  S  +P  CR+ QEI +QEQ++ LS G +PR++ V+L+DDLVD  K GDDV + G V++RW  L ++  C +++V+ AN I  VN+       I  E++ +++ FWEKY       RN +++ +CP ++GM+ +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGST+AGLTVTAVK+SG W+LEAGALVLADGG+CCIDEF SI+E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +SI+ N A+ASPLLSRFDL+ +LLD  NE WD  +S FIL  +     S + +++EK+K+YF  I++   PKM+ +A+VIL +YY   R+S   N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V++MES++ G  +L     L ++FP +P E+YR+    + ++L ++  +
Sbjct:   14 VFESFVLEHHQKEIAQILTEKYEDA-----HYSLVVNAMTLFEANMEIGEYFNAFPNEVLPIFDNALRRAAMSFLQSCSEKQTLVMKQ--NFHARITGLPVCPELTREHIPRTRDVGHFLSVTGTVIRTSLVKVLEYEQDFMCNKCKHVVTVK-ADFEQYYTFKPPITCSN-EEGCNSSKFTCLSDSS-TPASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLVDSCKSGDDVTVYGVVMQRWKPLYIDTRCDLEIVLKANYI-AVNNEQPCGVVINEEVRKEYEGFWEKYRNSPLEGRNEILASLCPQVFGMFVVKLAVAMVLAGGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKDSGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPEESISVNVALASPLLSRFDLVLVLLDTKNEDWDRIISSFILESKGCPRKSDKLWSMEKMKTYFCLIKN-LQPKMSQDANVILVRYYQLQRQSSCRNAA-RTTIRLLESLIRLAEAHARLMYRDVVTTEDAITVVSIMESSMQGGALLGGVNALHTSFPENPREQYRMQCELLLERLGLQKLL 646          

Query:   93 HYFLNILTDYLSKNHIQDIQNIINASFKKSINEC-----ETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSK-----ESFNL-----------EKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            H F N L  ++ + H  ++       FK+ I++      E+LV+  + +   +    ++ +L     +++KIF+   AK +   +      + +EI    VRI+ LP  +E+      + + + + +  +  V     +       +Y C KC F ++  F +S        P  C      C S   F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + GT    ++      N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   +  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC++IAA+NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++    +   SSK     E F L           E LK Y  Y +   HPK+       + K Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V E+D  MA+ VM
Sbjct:  201 HRFKNFLRTHVDE-HGHNV-------FKEKISDMCKENKESLVVNYEDLAAREHV--LAYFLPEAPAEMLKIFDEA-AKEVVLVMYPKYDRIAREI---HVRISHLPLVEELRSL---RQLHLNQLIRTSGVVTCCTGVLPQLSMVKYNCNKCNF-ILGPFFQSQNQEV--KPGSCPE----CQSLGPFEI----NMEETVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGTYHNNYDGSLNTANGFPVFATVILANHITKKDDKVAVGELTDEDVKAIIALSKDERIGER------IFASIAPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTKEWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTIIAASNPIGGRYDPSLTFSENVDLTEPIVSRFDILCVVRDTVDPVQDEMLARFVVGSHIKHHPSSKDIANGEEFALPNTFGVEPLPQEVLKKYIMYSKEKIHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVVEDDVNMAIRVM 797          

Query:   93 HYFLNILTDYLSKNHIQDIQNIINASFKKSINEC-----ETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSK-----ESFNL-----------EKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            H F N L  ++ + H  ++       FK+ I++      E+LV+  + +   +    ++ +L     +++KIF+   AK +   +      + +EI    VRI+ LP  +E+      + + + + +  +  V     +       +Y C KC F ++  F +S        P  C      C S   F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + GT    ++      N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   +  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC++IAA+NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++    +   SSK     E F L           E LK Y  Y +   HPK+       + K Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V E+D  MA+ VM
Sbjct:  181 HRFKNFLRTHVDE-HGHNV-------FKEKISDMCKENKESLVVNYEDLAAREHV--LAYFLPEAPAEMLKIFDEA-AKEVVLVMYPKYDRIAREI---HVRISHLPLVEELRSL---RQLHLNQLIRTSGVVTCCTGVLPQLSMVKYNCNKCNF-ILGPFFQSQNQEV--KPGSCPE----CQSLGPFEI----NMEETVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGTYHNNYDGSLNTANGFPVFATVILANHITKKDDKVAVGELTDEDVKAIIALSKDERIGER------IFASIAPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTKEWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTIIAASNPIGGRYDPSLTFSENVDLTEPIVSRFDILCVVRDTVDPVQDEMLARFVVGSHIKHHPSSKDIANGEEFALPNTFGVEPLPQEVLKKYIMYSKEKIHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVVEDDVNMAIRVM 777          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ +F+S   +   + L  +  T G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK   + E ++ +  +T + P  C + +S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDL+ +LLD  NE WD  +S FIL ++ + S  E+ +++EK+K+YF  IR+  HP ++  ++ +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R  V  EDAV AV+VMES++ G  +L     L ++FP +P  +Y+     I +KL+++  +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMSLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAILQSLPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFMVE-ADFEQYYTFSRPSSCPSLAS-CDSSKFSCLSDLSSSPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDVRCEVEIVLKANYVQ-VNNEQSSGMVMDEDTRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPKESVSVNIALGSPLLSRFDLVLVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRN-LHPTLSEVSNQVLLRYYQMQRQSDSRNAA-RTTIRLLESLIRLAEAHARLMFRSAVTLEDAVTAVSVMESSMQGGALLGGVNALHTSFPENPRAQYQRQCELILEKLELQGLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ +F+S   +   + L  +  T G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK   + E ++ +  +T + P  C + +S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDL+ +LLD  NE WD  +S FIL ++ + S  E+ +++EK+K+YF  IR+  HP ++  ++ +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R  V  EDAV AV+VMES++ G  +L     L ++FP +P  +Y+     I +KL+++  +
Sbjct:  167 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMSLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAILQSLPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFMVE-ADFEQYYTFSRPSSCPSLAS-CDSSKFSCLSDLSSSPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDVRCEVEIVLKANYVQ-VNNEQSSGMVMDEDTRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPKESVSVNIALGSPLLSRFDLVLVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRN-LHPTLSEVSNQVLLRYYQMQRQSDSRNAA-RTTIRLLESLIRLAEAHARLMFRSAVTLEDAVTAVSVMESSMQGGALLGGVNALHTSFPENPRAQYQRQCELILEKLELQGLL 801          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAG 1244
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ +F+S   +   + L  +  T G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK   + E ++ +  +T + P  C + +S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AG
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMSLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAILQSLPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFMVE-ADFEQYYTFSRPSSCPSLAS-CDSSKFSCLSDLSSSPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDVRCEVEIVLKANYVQ-VNNEQSSGMVMDEDTRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAG 384          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXX---------------------XXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNA 1241
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ +F+S   +   + L  +  T G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK   + E ++ +  +T + P  C + +S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD                      +  GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+A
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMSLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAILQSLPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFMVE-ADFEQYYTFSRPSSCPSLAS-CDSSKFSCLSDLSSSPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSVLQCHLTVHDLPAGLTWVLSLGDDLTIYGVVMQRWKPFQRDVRCEVEIVLKANYVQ-VNNEQSSGMVMDEDTRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSA 404          

Query:   81 IEGRHYFLNILTDYLSKNHIQDIQNIINASFKKSINEC-----ETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFIL-----------------NHQTFESSK------ESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            +E  H F N L  ++  +H  ++       FK+ I++      E+LV+  + +   +    ++ +L     +L++IF+    +++ +    M     +   +  VRI+ LP  +E+      + + + + +  +  V     +       +Y C KC F V+  F +S        P  C    S   +  F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + G     ++      N   V   +ILAN +   ++ ++       ++K+   L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K++ R++ TTG G++  GLT    +   S  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+VIAA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++                 N  T E +       E    E LK Y  Y +    PK+       + + Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V E+D  MA+ VM
Sbjct:  193 LEIHHRFKNFLRTHVD-SHGHNV-------FKERISDMCKENRESLVVNYEDLAAREHV--LAYFLPEAPAELLQIFDEAALEVVLA----MYPKYDRITNHIHVRISHLPLVEELRSL---RQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNF-VLGPFCQSQNQEV--KPGSCPECQS---AGPFEI----NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEK------IFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTLEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVM 798          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     L ++ M L +    I  Y      +++ +F+S   +   + L  +    G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F+V  +F +    +T + P  C + S  C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E+ +++EK+K+YF  IR+  HP ++  ++ +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R  V  EDA+  V+VMES++ G  +L     L ++FP  P  +YR     I +KL+++S +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPLVVNAMTLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAVLQSLPEPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKYVFTVKADFEQY---YTFSRPSSCPS-SDTCDSSKFTCLSDLSASPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDMRCEVEIVLKANYVQ-VNNEQSSGMVMDEDARKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRN-LHPTLSDVSNQVLLRYYQMQRQSDSRNAA-RTTIRLLESLIRLAEAHARLMFRSTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPESPRAQYRRQCELILEKLELQSLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ +F+S   +   + L  +  T G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK   + E ++ +  +T + P  C + +S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDL+ +LLD  NE WD  +S FIL ++ + S  E+ +++EK+K+YF  IR+  HP ++  ++ +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R  V  EDAV AV+VMES++ G  +L     L ++FP +P  +Y+     I +KL+++  +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMSLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAILQSLPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFMVE-ADFEQYYTFSRPSSCPSLAS-CDSSKFSCLSDLSSSPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDVRCEVEIVLKANYVQ-VNNEQSSGMVMDEDTRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPKESVSVNIALGSPLLSRFDLVLVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRN-LHPTLSEVSNQVLLRYYQMQRQSDSRNAA-RTTIRLLESLIRLAEAHARLMFRSAVTLEDAVTAVSVMESSMQGGALLGGVNALHTSFPENPRAQYQRQCELILEKLELQGLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDM----GVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ IF+S   +   + L  +     V++ +   N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F +  +F +    +T   P  C +  S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN IQ VN+  S+   +  E++ +F+ FWE Y    F  RN++++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E  +++EK+K+YF  IR+   P ++   + +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V+VMES++ G  +L     L ++FP +P E+Y+     I +KL+++S +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQ---NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQY---YTFCRPSSCPSLES-CDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQ-VNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRN-LQPTLSDVGNQVLLRYYQMQRQSDCRNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPENPGEQYQRQCELILEKLELQSLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ IF++   +   + L  +    G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   +++LEF+R+Y+C KCK  F V  +F +    +T   P  C +  + C SS F  + S   SP  CR+ QEI +QEQ++ LS G +PR+++VIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN IQ VN+  S   ++  E++ +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A++SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E  +++EK+KSYF  IR    P ++ E + +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDAV  V+VMES++ G  +L     L ++FP +P ++Y+     I +KL++ + +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQY---YTFFRPSSCPSLEN-CDSSKFTCL-SDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQ-VNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRK-LQPTLSDEGNQVLLRYYQMQRQSDSRNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLL 644          

Query:  108 ILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCS---SLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTF-ESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
            +   ++ ++H ++I  I+   ++ +        L ++ M L +    I  Y      +++ IF++   +   S   S ++    + K+  N   RIT LP C E++R  IP++ DVG FLSV  TV+R   ++VLE++++++C KCK  V  + ++ +  +T  PP  CSN   GC SS F  +  S  +P  CR+ QEI +QEQ++ LS G +PR++ V+L+DDLVD  K GDDV + G V++RW  L ++  C +++V+ AN I  VN+       I  E++ +++ FWEKY       RN +++ +CP ++GM+ +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGST+AGLTVTAVK+SG W+LEAGALVLADGG+CCIDEF SI+E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +SI+ N A+ASPLLSRFDL+ +LLD  NE WD  +S FIL  +     S + +++EK+K+YF  I++   PKM+ +A+VIL +YY   R+S   N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V++MES++ G  +L     L ++FP +P E+YR+    + ++L ++  +
Sbjct:   14 VFESFVLEHHQKEIAQILTEKYEDA-----HYSLVVNAMTLFEANMEIGEYFNAFPNEVLPIFDNALRRAAMSFLQSCSEKQTLVMKQ--NFHARITGLPVCPELTREHIPRTRDVGHFLSVTGTVIRTSLVKVLEYEQDFMCNKCKHVVTVK-ADFEQYYTFKPPITCSN-EEGCNSSKFTCLSDSS-TPASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLVDSCKSGDDVTVYGVVMQRWKPLYIDTRCDLEIVLKANYI-AVNNEQPCGVVINEEVRKEYEGFWEKYRNSPLEGRNEILASLCPQVFGMFVVKLAVAMVLAGGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKDSGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPEESISVNVALASPLLSRFDLVLVLLDTKNEDWDRIISSFILESKGCPRKSDKLWSMEKMKTYFCLIKN-LQPKMSQDANVILVRYYQLQRQSSCRNAA-RTTIRLLESLIRLAEAHARLMYRDVVTTEDAITVVSIMESSMQGGALLGGVNALHTSFPENPREQYRMQCELLLERLGLQKLL 646          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMG----VTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     + ++ M L +    I  Y      +++ +F+S   +   + L  +     V++ +   N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F V  +F +    +T   P  C +  S C SS F  + S   SP  CR+ QEI +QEQ++ LS G +PR++KV+L+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+  ++  E++ +F+ FWE Y    F  RN +++ +CP I+GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E  +++EK+K+YF  IR+   P ++   + +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V+VMES++ G  +L     L ++FP +P E+Y+     I +KL+++S +
Sbjct:   15 QVFESYVSEYHKNDILLIL-----KERDEDAHYAVVVNAMTLFETNMEIGEYFTVFPNEVLSVFDSALRRSALTILQSLSQPECVSMKQ---NLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHIFVVKADFEQY---YTFCRPSSCPSLES-CDSSKFTCLSSLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVVLEDDLVDSCKSGDDLTIYGVVMQRWKPFQQDVRCEVEIVLKANYVQ-VNNEQSSGITMDEEVRKEFEDFWECYKSDPFAGRNEILASLCPQIFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRN-LQPSLSDVGNQVLLRYYQMQRQSDARNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPENPREQYQRQCELILEKLELQSLL 649          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEI---PNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   YL ++H  DI  I+    +++ +E    +L +D + L +    I  Y      +++ IF+    +   + L     T   E+   PN   RI+ LP C E++R  IPK+ DVG FLSV  TV+R   ++VLEF+R YIC KCK   + + ++ +  +    P  C N   GC S+ F  +  +  SP  CR+ QEI +QEQ++ LS G +PR + V+L+DDLVD  K GDD+ + G V++RW     +  C ++LV+ AN I++ N  ++    I  E++ +F+ FWEK+       RN +++ +CP ++G+Y +KLA+A+VL G  +     G ++RGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGST+AGLTVTAVK+ G W+LEAGALVLADGG+CCIDEF SI+E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG+YD T+S++ N A+ SPLLSRFDL+ +LLD  NE WD  +S FIL ++   S  E  +++EK+K+YF  I+    PK++ E+++IL +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDAV  V+VMES++ G  +L     L ++FP +P  +YR+    I ++L+++  +
Sbjct:   15 QVFESYLLQHHRDDILGIL----RQADDEAHYPIL-VDALTLFETNMEIGEYFNAFPSQVLPIFDGALRRAAMAVLQ--AATPSPELRMKPNLHTRISGLPICPELTREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAK-ADFEQYYAFCRPSACLN-EEGCNSTKFTCLSGTSSSPTSCRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVVMQRWKPFHQDARCDLELVLKANYIKVNNEQLAG-VIIDEEVRKEFEDFWEKHRNNPLAGRNEILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKDFGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGHYDPTESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGCPSKSEKLWSMEKMKTYFCLIKR-IQPKLSDESNLILVRYYQMQRQSDCRNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGAINALHTSFPENPVAQYRMQCELILERLELQHLL 649          

Query:   99 FLNILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEI-PNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQ----TFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEY-RLLKLNIFKKLQIKSFI 2030
            ++ I   +L ++H +DI N++ A    S        + ++V+ L      +S  LL +  K++ +F+   A+   S + +    +      +  VR+++LP C E+ R  IPK+ D+G+FL+++ TV+R  ++++LE++R+YIC +CK  F V  +F +    ++I  P  C + S  C S+ F  +      PK CR+ QEI +QEQ++ L+ G +PR++ VIL+DDLVD  K GDD+ + G V+RRW  +  +  C +++V  AN +  VN+       +  E+K +F  FWE++       RN ++S  CP +YG+Y +KLA+AL+L G  +    +G +VRGESH+L+VGDPGT KSQFLK+A K+ PRSVLTTGIGST+AGLTV AV++SG W LEAGALVLADGG+CCIDEF SI+E D+  IHEAMEQQ+ISVAKAG+VCKL TR +V+AATNPKG YD ++S++ N A+ASPLLSRFDL+ +L D  NE WD  VS FIL  +    T  SS+  +++EK+++YF Y++ T  P++TPE++ IL +YY   R++++ N+  R T+R LESLIRL+Q+HAR M REFV  +DA+ AV  +E ++  S +L +   L + FP DP+EEY R  KL + K+LQ+   +
Sbjct:   12 YIAIFQAFLEEHHKEDILNVLMADDPSS-----QYCVVVNVLELFDSNIEVSQKLLADPNKMLPLFDGALAQAAVSIMQESTTQISMSFKAHLHVRLSNLPICPELRRDKIPKTSDIGRFLAISGTVIRVSTVKLLEYERDYICARCKHIFGVQADFEQF---YSIPKPSKCPS-SKECNSNKFSCLSDGASEPKSCRDYQEIKIQEQVQKLAVGTIPRSMWVILEDDLVDCCKAGDDITVCGVVMRRWKPVFPDSRCDLEVVFKANHVS-VNNEQKATVLVTEELKREFAEFWERFKQSPLQGRNHILSSFCPQVYGLYAVKLAVALILIGGVQRVDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKIMPRSVLTTGIGSTSAGLTVAAVRDSGEWQLEAGALVLADGGLCCIDEFNSIQEHDRTCIHEAMEQQTISVAKAGMVCKLSTRTTVLAATNPKGPYDPSESLSVNIAVASPLLSRFDLLLVLHDARNEEWDRIVSSFILEGKGLSTTASSSEPLWSMEKMQAYFCYVK-TLKPQLTPESNRILSRYYHCQRQADLRNAA-RTTIRLLESLIRLAQAHARLMCREFVTVQDAITAVTCVECSMQNSALLGSMNALHTKFPDDPQEEYSRQAKL-VLKRLQLNDMV 651          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S+ H  DI  I+     K  +E     L ++ M L +    I  Y      +++ +F+S   +   + L  +    G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F+V  +F +    +T + P  C + S  C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  + + +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+A+VL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E+ +++EK+K+YF  IR+  HP ++  ++ +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R  V  EDA+  V+VMES++ G  +L     L ++FP  P  +YR     I +KL+++S +
Sbjct:   11 QVFESYVSEYHKNDILLIL-----KERDEDAHYPLVVNAMTLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAVLQSLPEPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKYVFTVKADFEQY---YTFSRPSSCPS-SDTCDSSKFTCLSDLSASPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDMRCEVEIVLKANYVQ-VNNEQSSGMVMDEDARKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRN-LHPTLSDVSNQVLLRYYQMQRQSDSRNAA-RTTIRLLESLIRLAEAHARLMFRSTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPESPRAQYRRQCELILEKLELQSLL 645          

Query:  105 NILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIP-NCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
             +   Y+S++H  DI  I+  S     +E     + ++ M L +    I  Y      +++ +F++   +   + L  +    G  +  N   RI+ LP C E+ R  IPK+ DVG FLSV  TV+R   ++VLEF+R+Y+C KCK  F+V  +F +    +T   P  C +  S C SS F  +     SP  CR+ QEI +QEQ++ LS G +PR++KVIL+DDLVD  K GDD+ I G V++RW   + +  C +++V+ AN +Q VN+  S+   +  E++ +F+ FWE Y    F  RN +++ +CP ++GMY +KLA+ALVL G  +     G +VRGESH+L+VGDPGT KSQFLK+A K+TPRSVLTTGIGST+AGLTVTAVK+SG W+LEAGALVLAD G+CCIDEF S++E D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG YD  +S++ N A+ SPLLSRFDLI +LLD  NE WD  +S FIL ++ + S  E  +++EK+K+YF  IR    P ++   + +L +YY   R+S+  N+  R T+R LESLIRL+++HAR M R+ V  EDA+  V+VMES++ G  +L     L ++FP +P E+Y+     I +KL+++S +
Sbjct:   11 QVFESYVSEHHKNDILLILKES-----DEDAHYSVVVNAMTLFETNMEIGDYFTVFPNEVLTVFDNALRRSALAILQSLSQPEGASMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFAVSADFEQY---YTFCRPSSCPSLES-CDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQKLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQQDVRCEVEIVLKANYVQ-VNNEQSSGVIMDEEVRKEFEDFWEYYKSDPFAGRNEILASLCPQVFGMYLVKLAVALVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDHIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRK-LQPSLSDVGNQVLLRYYQMQRQSDCRNAA-RTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPENPREQYQRQCELILEKLELQSLL 645          

Query:  108 ILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLG-KEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYR 1982
            +   Y++++H  DI  I+     +  +E     L ++ M L +    +  Y      +++ +F+S   K   S      +  G K   N  VRI+ LP C E+SR  IPK+ DVG FLSV  TV+R    +VLE++R+Y+C KC+  FSV  +F +    ++ +PP  C +    C S  F  +  S  +P  C++ QEI +QEQ++ LS G +PR++ VIL+DDLVD  K GDD+ + G + +RW  L  +  C +++V+ AN I+I N   +   +++ + + +F+ FWE +       RN ++  +CP ++GMY +KLA+ +VL G  +    +G KVRGESH+L+VGDPGT KSQFLK+A K+TPRSVLT GIGSTNAGLTV AVK+SG W LEAGALVL+DGG+CCIDEF SI+E D+ +IHEAMEQQSISVAKAG+VCKL TR +++AATNPKG YD   S++ N A+ASPLLSRFDL+ +LLD  N  WD  +S FIL ++   S   S +++EK+++YF  I+    P +T EA+ IL +YY   R+++ + S  R T+R LESL RL+++HAR M RE V  EDAV+AV+VME ++ G  +L     L ++FP +P E+YR
Sbjct:   14 VFETYVAEHHKSDILQIL-----QEPDEDAHYPLVVNAMSLFEANMEVGEYFNALPSEVLPVFDSALHKAATSISQTESLHRGLKPKCNMHVRISGLPVCPELSRDHIPKARDVGHFLSVTGTVIRTSVTKVLEYERDYMCNKCRHVFSVQADFEQF---YSFSPPSHCPSEDE-CNSFKFTCLADSDAAPAACKDYQEIKIQEQVQRLSVGSIPRSMLVILEDDLVDRCKSGDDITVYGVLWQRWKPLYQDSRCDVEIVLKANYIEINNDQSTAAVALE-DFQKEFEEFWENHKQDPIAGRNQILMSLCPQVFGMYVVKLAVGMVLAGGVQRVDASGTKVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTNAGLTVAAVKDSGEWHLEAGALVLSDGGLCCIDEFNSIKEHDRTSIHEAMEQQSISVAKAGMVCKLDTRTTILAATNPKGPYDPNVSVSVNVAVASPLLSRFDLVLVLLDTKNPEWDKIISSFILQNKGAPSQSSSLWSMEKMRAYFCVIK-RLRPNITQEANSILARYYQLQRQND-SRSAARTTIRMLESLGRLAEAHARLMFREIVTVEDAVVAVSVMECSMQGGALLGNVNTLHTSFPDNPREQYR 631          

Query:  249 ISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWN---NLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSKES------------------FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            ++ +L     +++KIF+   AK +  ++      +  EI    VRI +LP  +E+      + + + + +  +  V     +       +Y C KC F ++  F +S        P  C      C S   F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + G     ++   N+  N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   +  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+V+AA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++    +   S+KE                      E L+ Y  Y +    PK+       + + Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V+E+D  MA+ VM
Sbjct:  223 LAYFLPEAPAEMLKIFDEA-AKEVVLAMYPKYDRIAHEI---HVRIGNLPLVEELRSL---RQLHLNQLIRTSGVVTSCTGVLPQLGMVKYNCNKCSF-ILGPFFQSQNQEV--KPGSCPE----CQSLGPFEI----NMEQTVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDHCKPGDEIELTGIYHNNYDGSLNM-ANGFPVFATVILANHIARKDDRVAVAELTDEDVKAIVALSKDERIGER------IFASIGPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLMCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVMAAANPIGGRYDPSLTFSENVDLTEPIVSRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSNKEGGVAGLEEVVLPNSSDVPPIPQELLRKYIIYAKERVRPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVQEDDVNMAIRVM 774          

Query:  249 ISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSKES------------------FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            ++ +L     +++KIF+   AK +  ++      +  EI    VRI +LP  +E+      + + + + +  +  V     +       +Y C KC F ++  F +S        P  C      C S   F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + G     ++      N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   +  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+V+AA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++    +   S+KE                      E L+ Y  Y +    PK+       + + Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V+E+D  MA+ VM
Sbjct:  223 LAYFLPEAPAEMLKIFDEA-AKEVVLAMYPKYDRIAHEI---HVRIGNLPLVEELRSL---RQLHLNQLIRTSGVVTSCTGVLPQLGMVKYNCNKCSF-ILGPFFQSQNQEV--KPGSCPE----CQSLGPFEI----NMEQTVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDHCKPGDEIELTGIYHNNYDGSLNMANGFPVFATVILANHIARKDDRVAVAELTDEDVKAIVALSKDERIGER------IFASIGPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLMCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVMAAANPIGGRYDPSLTFSENVDLTEPIVSRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSNKEGGVAGLEEVVLPNSSDVPPIPQELLRKYIIYAKERVRPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVQEDDVNMAIRVM 774          

Query:  249 ISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVS-SAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWN---NLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSKES------------------FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            ++ +L     +++KIF+   AK +  ++      +  EI    VRI +LP  +E+      + + + + +  +  V     +       +Y C KC F ++  F +S        P  C      C S   F+I     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + G     ++   N+  N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IYG   +K  LAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   +  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+V+AA NP  G YD + + + N  +  P++SRFD++ ++ D  +   D  ++ F++    +   S+KE                      E L+ Y  Y +    PK+       + + Y+ +RK  +      IT+R +ES+IR++++HAR  +R++V+E+D  MA+ VM
Sbjct:  232 LAYFLPEAPAEMLKIFDEA-AKEVVLAMYPKYDRIAHEI---HVRIGNLPLVEELRSL---RQLHLNQLIRTSGVVTSCTGVLPQLGMVKYNCNKCSF-ILGPFFQSQNQEV--KPGSCPE----CQSLGPFEI----NMEQTVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDHCKPGDEIELTGIYHNNYDGSLNM-ANGFPVFATVILANHIARKDDRVAVAELTDEDVKAIVALSKDERIGER------IFASIGPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLMCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVMAAANPIGGRYDPSLTFSENVDLTEPIVSRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSNKEGGVAGLEEVVLPNSSDVPPIPQELLRKYIIYAKERVRPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVQEDDVNMAIRVM 783          

Query:  447 GKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQI--KYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI---RRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHG-KSFTARN----LLISQMCPLIYGMYFLKLALALVLCGSENCFF---NGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGG--WSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQ----------------TFESS--------------------KESFN---LEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV 1907
            GKF+++  TVVR  +I+ L  +  +IC  C  +   +    D  +T   P  C      C    F    SS L+     + Q I VQE I       G +PRTI+  L  DLVD   PGD V I G +       +     D+C+  L I AN +       S + S         +   +  +G +   A+     L+++ +CP IYG   +K  LAL L G    +    N + +RG+ H+L+VGDPG  KSQ L+    ++PR +   G  +T++GLTV+  ++SG   ++LEAGALVL D GICCIDEF  +    + A+ EAMEQQSIS+AKAGIVC L  R S+IAA NP  G+Y+  ++++ N  + S LLSRFDL+F+LLD  NE  D  +S+ I+  +                T ES+                     E+F+    + L+ Y  Y R   HP ++ EA+ +L+ +Y  +RK   +     IT R LESLIRL+++ AR  +RE   E DA   V +M+ ++
Sbjct:  159 GKFVAIRGTVVRVSNIKPLCSKMAFICNSCGDTQSLDLP--DGKYTT--PSKCPQKE--CRGRIFTPNRSSPLT--LTVDWQTIKVQELISDDQRESGRIPRTIECELTQDLVDSCVPGDMVTITGIIKVSNEEGSGRNKKDKCMFLLYINANSVSNSKGQKSKSASEPESQGASVEFSLKDLYGIQEIQAQEDLFKLIVNSLCPAIYGHLLVKAGLALALFGGCQKYVDDKNRIPIRGDPHVLVVGDPGLGKSQMLQAVCNVSPRGIYVCGNTTTSSGLTVSLSRDSGSGDYALEAGALVLGDQGICCIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGIVCTLPARTSIIAAANPVGGHYNKGKTVSENLKMGSALLSRFDLVFILLDTPNEDHDHMLSEHIMAMRAGKKGMVSSAAVARNCTQESNISILEISSDQPLSDRLKVLPGENFDPIPHQLLRKYVGYARHYVHPNLSAEAAQVLQDFYLELRKQNQSADSTPITTRQLESLIRLTEARARLELREKATESDAEDVVDIMKHSL 691          

Query: 1023 MCPLIYGMYFLKLALA-LVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESG--GWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAK-AGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-----HQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDR-------ITMRFLESLIRLSQSHARFMMREF-----VKEEDAVMAVAVMESTVYGS 1916
            + P IYG   +K A+A L++ GS     +G+  RG+ ++L++GDPGTAKSQ LKF  + +P  V T+G GS+ AGLT + +++     + +E GA+VLADGG+ CIDEF  +RE D+VAIHEAMEQQ+IS  +  GI   L +RCSV+AA N   G +D ++    N      +LSRFD+IF++ D  NE  D  ++  ++N         ++ +    L  LK + AY RS   P+M+ EA   L+  Y  MR     +  DR       IT+R LE+++R+S+S A+  ++ F     V E   +  V+ +++ + GS
Sbjct:  148 IAPSIYGFMDIKKAIASLLIGGSRKRLPDGLTRRGDINLLLLGDPGTAKSQLLKFVERCSPIGVYTSGKGSSAAGLTASVMRDPATRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISTLRIGGITTTLNSRCSVLAAANSVFGRWDDSKG-EENIDFMPTILSRFDMIFIIKDEHNEKRDMILAKHVMNVHLNAKTQMQAVEGEIELSTLKKFIAYCRSKCGPRMSAEACEKLKNRYVLMRSGAREHDRDRDHRNSIPITVRQLEAIVRISESQAKMRLQPFATEAHVDEALRLFQVSTLDAALSGS 466          

Query:  447 GKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQI--KYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTV----IRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSE--MKLDFQLFWEKYHGKSFTAR----NLLISQMCPLIYGMYFLKLALALVLCGSENCFF---NGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQ---------------------TFESSKE--------SFNLEK-------------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMEST 1904
            G+ +++  TVVR G+I+ L  +  + C  C    +         FT+ P K        C S  F     S+L+     + Q I VQE +  +    G +PRT++  L  DLVD   PGD + + G V         N    D+C+  L I A  +       S+     +   + LDF L  E Y  +   A+     LL+  +CP IYG   +K  LAL L G    +    N + VRG+ H+LIVGDPG  KSQ L+    + PR V   G  +T AGLTVT  K+  SG ++LEAGALVL D G+CCIDEF  +    + A+ EAMEQQSIS+AKAG+VC L  R S++AA NP  G+Y+ +++++ N  + S LLSRFDL+F+L+D  +E  D  +S+ ++                        T  SS +        S  L+              L+ Y  Y R    P ++ EA+  L+ +Y  +R+         IT R LESLIRL+++ AR  +RE   +EDA   + +M+ +
Sbjct:  220 GRLVAIRGTVVRVGNIKPLCTRLAFSCNACGTEQVLRLPY--GKFTL-PTKRVKCADEDCRSRTFMPNRRSQLTETV--DWQNIKVQELMHGEQREAGRIPRTVECELTHDLVDSCVPGDVITLTGIVKVASSDEGRNKSNKDKCMFLLYIQAVAVSNTKGQRSDGGGEDTAPGVALDFSL-KELYAVQEIQAQPHLFRLLVHSICPTIYGHELVKAGLALALFGGVQRYGTDKNRIPVRGDPHVLIVGDPGLGKSQMLQAVCNIAPRGVYVCGNTTTTAGLTVTLSKDGPSGDYALEAGALVLGDQGLCCIDEFDKMPNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIVAAANPVCGHYNKSKTVSENLKMGSALLSRFDLVFILVDTPDEERDHVLSEHVMAMHAGKRMLAGASVSRAAAPGLKLTASSSSDDVLGGLSLSDRLKARRGEALDPVPHSLLRKYVGYARRYVRPCLSAEAAQTLQDFYLELRRQHHGGDGTPITTRQLESLIRLTEARARLELRENATKEDADDVIDIMKHS 758          

Query:  681 RNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLA-LALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLT--VTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKE 1640
            R+ Q I++QE  +    G +PR+  V+LDDDLVD  KPGD V + GT                + +++ N ++ +N  +   +S +   K+     + K H K+    + L   + P I+G  ++K A L L+L G+E    NG ++RG+ ++L++GDP  AKSQ L++     PR++ TTG GS+  GLT  VT  +E+G   LEAGA+VL D G+ CIDEF  + + D+ AIHE MEQ  +++AKAGI  +L  RCSV+AA NP  G YD  ++   N  +   LLSRFDL+F++LD  +  +D  +SD +L    + +  E
Sbjct:  131 RDHQTISLQEMPEKAPAGQLPRSADVVLDDDLVDRCKPGDRVQVIGTFRCLPGKKAGYTSGTFRTILIGNNVKQMNKEVVPTFSGEDVNKIKT---FSKTHSKNIF--DQLSKSLAPSIHGHEYIKKAVLCLLLGGTEKILDNGSRIRGDINVLLIGDPSVAKSQMLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLGDRGVVCIDEFDKMTDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPIYGRYDQYKTPMENIGLQDSLLSRFDLLFIVLDQTDPEYDREISDHVLRMHRYRAVGE 449          

Query:  432 KSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRW-NNLRVNDECVIQLVIL-ANEIQIVNHTISNNYSIK--SEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKA--GIVCKLKTR 1442
            K+  +G+ ++V   V RA  ++ +     Y C +C      E  +  AS +  P   C +       S   +   S+ S KF +  QE+ +QE    +  GC+PR + V +  +   L +PGD + I G  +       R   + ++    L A+ +  +N T  N   ++  SE +L  Q+  E ++ K       L + + P IYG   +K AL L+L G  +    GMK+RG  ++ ++GDPG AKSQ L +  +L PRS  TTG GS+  GLT   +++  +G  +LE GALVLAD G+CCIDEF  + + D+ +IHE MEQQ+IS+AK   G+    +TR
Sbjct:  152 KANSIGRLVTVRGVVTRATEVKPMMVVATYTCDQCG----AETYQPIASTSFMPLALCPSRDCQTNKSGGRLYLQSRGS-KFVKF-QELKIQEHSDQVPVGCIPRAMTVCVRGENTRLAQPGDHISITGIFLPVLKQGFRAMQQGLLSETFLEAHRVVKMNKTEDNELDVEELSESEL-RQITEEDFYEK-------LAASIAPEIYGHEDVKKALLLLLVGGVDRSPRGMKIRGNINICLMGDPGVAKSQLLCYIDRLAPRSQYTTGRGSSGVGLTAAVLQDPLTGEMTLEGGALVLADHGVCCIDEFDKMADSDRTSIHEVMEQQTISIAKVTWGVGASTRTR 482          

Query:  432 KSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRW-NNLRVNDECVIQLVIL-ANEIQIVNHTISNNYSIK--SEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKA--GIVCKLKTRCS 1448
            K+  +G+ ++V   V RA  ++ +     Y C +C      E  +  AS +  P   C +       S   +   S+ S KF +  QE+ +QE    +  GC+PR + V +  +   L +PGD + I G  +       R   + ++    L A+ +  +N T  N   ++  SE +L  Q+  E ++ K       L + + P IYG   +K AL L+L G  +    GMK+RG  ++ ++GDPG AKSQ L +  +L PRS  TTG GS+  GLT   +++  +G  +LE GALVLAD G+CCIDEF  + + D+ +IHE MEQQ+IS+AK   G+    +  CS
Sbjct:  152 KANSIGRLVTVRGVVTRATEVKPMMVVATYTCDQCG----AETYQPIASTSFMPLALCPSRDCQTNKSGGRLYLQSRGS-KFVKF-QELKIQEHSDQVPVGCIPRAMTVCVRGENTRLAQPGDHISITGIFLPVLKQGFRAMQQGLLSETFLEAHRVVKMNKTEDNELDVEELSESEL-RQITEEDFYEK-------LAASIAPEIYGHEDVKKALLLLLVGGVDRSPRGMKIRGNINICLMGDPGVAKSQLLCYIDRLAPRSQYTTGRGSSGVGLTAAVLQDPLTGEMTLEGGALVLADHGVCCIDEFDKMADSDRTSIHEVMEQQTISIAKVTWGVGASTRALCS 484          

Query: 1008 LLISQMCPLIYGMYFLKLALA-LVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTF---------ESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDR-------ITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMEST 1904
            +L + + P I+G   +K A+  L++ GS+    +GM++RG+ ++L++GDPGTAKSQ LKF  K++P +V T+G GS+ AGLT +  ++  +  + LE GA+VLADGG+ CIDEF  +R+ D+VAIHEAMEQQ+IS+AKAGI   L +R SV+AA NP  G YD  +S   N    + +LSRFD+IF++ D+ NE  D  +++ ++N  T          E +    ++EK+K Y  Y R    P+++P+A+  L   +  +RK  + N L+        IT+R LE++IR+++S A+  +    +E     A+ + +++
Sbjct:  369 ILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQAS 687          

Query: 1011 LISQMCPLIYGMYFLKLALAL-VLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFI--LNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSE---ITNSLDRITMRFLESLIRLSQSHAR 1838
            L+  + P ++G   +K  + L +L G       G+K+RG+ ++ +VGDP T+KSQFLK+     PRSV T+G  S+ AGLT   V+  E G +++EAGAL+LAD GICCIDEF  +   D+VAIHEAMEQQ+IS+AKAGI   L  R S++AA NP  G Y+   S+  N  + +P++SRFDL F++LD+CNE  D+ ++  I  L+ +  E+ +  F+ E+L+ Y  Y R TF P +T EA   L + Y  +RK +    + S  RIT+R LES+IRLS++ AR
Sbjct:  529 LVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYAR-TFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIAR 812          

Query:  480 RAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWN-NLRV-NDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFT--ARNL-----LISQMCPLIYGMYFLKLALALVLCGSENCFFNGMK-VRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGN-YDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-----HQTFESSKESFNL-----------------------------------------EKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAF 1955
            R G    L++ + + C KC   +   F +S+    I+   FC+N    C S     V   K      RN Q + +QE    +  G +PR  +VIL  DLVD+ KPG++V + G     ++ NL   N   V   +I AN I+      +N    + E  LD    W +   + F   +R+      +IS M P IYG   +K A+A  L G      NG   +RG+ ++L++GDPGTAKSQ LK+  K   R+V  TG G++  GLT +  K+  +  W+LE GALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RCS+IAA NP G  Y+ T  +  N ++  P+LSRFD++ ++ D  +E  D  ++ F+++     H   +  +E   L                                         E L  Y  Y R+  +PK+       + + Y  +R+  I+     IT+R LES++R+++S A+  + EFV   D   A+ V+  +   +  +S  +QL  +F
Sbjct:  327 RTGVFPQLKYVK-FNCLKCGSILGPFFQDSNEEIRIS---FCTN----CKSKGPFRVNGEKT---VYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREGNTAN----EGEEGLDV-FSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSF 861          

Query: 1008 LLISQMCPLIYGMYFLKLALALVLCGSEN-CFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLT--VTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGN-YDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFE-----SSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLD--RI--TMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV 1907
            LL   + P IY +  +K  + L L G  N  F  G + RG+ ++L+ GDP T+KSQ L++ HK+TPR V T+G GS+  GLT  +T   ++    LE+GALVL+DGG+CCIDEF  + +  +  +HE MEQQ+IS+AKAGI+  L  R S++A+ NP G+ Y+    +T N  +  PLLSRFDL++L+LD  +E  D  ++  + N    +     S  +   +E L  Y +Y +   HP +T  A   L + Y  MRK    +  D  RI  T R LES+IRL+++HA+  ++  V+ ED   AV ++ S +
Sbjct:  521 LLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAI 833          

Query: 1005 NLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLT--VTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTF--------ESSKESFNL 1652
            ++L   + P IYG   +K A+ L+L G  E    NG  +RG+ ++L+VGDP TAKSQ L+F       ++ TTG GS+  GLT  VT  +E+G   LEAGA+VLAD G+ CIDEF  + + D+VAIHE MEQQ++++AKAGI   L  RCSVIAA NP  G YD+ +    N A+   LLSRFDL+F++ D+ NE  D  +S+ +L    +        E  +E  NL
Sbjct:  361 DILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNL 588          

Query: 1659 LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTV 1922
            L+ Y  Y +    P++T EA  ++ K YT +R  + T     IT R LE+LIRL+ +HA+  + + V + DA +A  ++   + G  +
Sbjct:  656 LRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKK-SPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDI 742          

Query:  366 PNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-----FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
            PN  VR+++LP C E+ R++IPKS D+G+FL+V+ TV+R  SI++LE +RE+IC +CK+ V    ++ +  +TI  P  C +   GC S+ F+ +     +P  CR+ QEI +QEQ++ L+ G +PR++ V+L+DDLVD  K GDDV I+G V+RRW  +    +C +++V  AN +  VN+       +  EMK +F  FW K+  K  + RN +++  CP +YG+Y +KLA+ L+L G  +    +G +VRGESHML++GDPGT KSQFLK++ K+ PRSVLTTGIGST+AGLTV AV++SG W LEAGALVLADGG+CCIDEF SIRE D+ +IHEAMEQQ+ISVAKAG+VCKL TR +++AATNPKG  DI QS++ NTA+ASPLLSRFDL+F+L D  NE WD  VS FIL  +    S E      + +++L++Y  + + T  P++  +++ +L +YY   R+++  N+  R T+R LESLIRL+Q+HAR M RE V  +DAV+AV  +E ++  + +L     L + FP DPE+EY+     I K+L +   +
Sbjct:    5 PNIHVRLSNLPICPELKRSTIPKSSDMGRFLAVSGTVIRVSSIKMLEHEREFICSRCKY-VFSAQADFEQFYTIPKPTSCPS-GEGCTSNKFNCLSEPGSNPTSCRDYQEIKIQEQVQKLAVGTIPRSMWVVLEDDLVDSCKAGDDVTISGVVMRRWWPVIAEVKCDLEVVFKANHVS-VNNEQRIGAIVTEEMKQEFDEFWSKHKDKPLSGRNHILASFCPQVYGLYAVKLAVTLILMGGVQRVDASGTRVRGESHMLLIGDPGTGKSQFLKYSAKIMPRSVLTTGIGSTSAGLTVAAVRDSGEWQLEAGALVLADGGLCCIDEFNSIREHDRGSIHEAMEQQTISVAKAGMVCKLNTRTTILAATNPKGQLDIDQSLSVNTALASPLLSRFDLVFVLQDVKNEDWDRIVSSFILEGKGVRMSAEKPAEALWGMDRLQAYICHAK-TLEPQLNTDSNRVLRQYYQCQRQADTRNAA-RTTLRLLESLIRLAQAHARLMYREHVTVQDAVVAVTCVECSMQNTALLGCMNALHTRFPDDPEQEYKQQAKLILKRLGLTDLM 560          

Query:  207 LRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQ------TFESSKES-----FNLEK-------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAF 1955
            L ID  IL  +   ++ +L     ++++IF+    +++ +    M     +      VRI  LP  +E+      + + V + +     V  +  I       +Y C KC F +   F  SD       P  C    S      F+I     +     +N Q+I +QE    ++ G +PR   VIL  DLVD  KPGD++ + G     +++   R N   V   +I AN I   +  ++       ++K    L  ++  G+       +I+ + P IYG   +K ALAL L G       G  K+RG+ ++L+ GDPGTAKSQFLK+  K  PR+V TTG G++  GLT    +   +  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RCS++AA NP  G YD + +   N  +  P+LSRFD++ ++ D  +   D  ++ F++N        T E+  E      F L +       LK Y  Y R   HP++       + K +  +RK  +      IT+R +ES+IR+++SHA+  +RE+V E+D  MA+ VM  +   +   S  + +  AF
Sbjct:  154 LVIDYNILANEQQVLAYFLPEAPTEMLQIFDEAAKEVVLA----MFPNYDRITTEIHVRIAELPLMEELRSL---RQLHVNQLIRTGGVVTSSTGIMPQLSVIKYDCPKCSFILGPFFQGSDQEVK---PGSCPECQS---RGPFEI----NMEQTLYQNYQKIKIQESPSKVAAGRLPRYKDVILMADLVDSCKPGDEIELTGIYKINYDSSLNRSNGFPVFATIIEANFITKQDDKMAVTSLTDEDIKAINALSKDERIGER------IIASIGPSIYGHEDIKRALALSLFGGVAKDPGGKHKIRGDINVLLCGDPGTAKSQFLKYVEKTAPRAVFTTGQGASAVGLTAYVQRHPVTKEWTLEAGALVLADKGMCLIDEFDKMNDADRTSIHEAMEQQSISISKAGIVTSLQARCSILAAANPIGGRYDPSLTFAENVDLTEPILSRFDILCVVRDTVDAIQDELLARFVVNSHVRHHPNTPENEDEDMEVHMFTLRRNAIPQDLLKKYMIYARERVHPRLNNMDQDKVAKMFADLRKESMATGSIPITVRHIESMIRMAESHAKMHLREYVMEDDVNMAIRVMLESFIDTQKFSVMRNMKKAF 737          

Query:  399 FCDEISRTSIPK--SVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSN-YSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI--------------------------------RRWNNLRVNDECVIQLVILANEIQIVNHTISNN---------YSIKSEMK-LDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-HQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRK---SEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV--YGSTVLSTDQQLPSAFPTDPEEE 1976
            F D  +R  I +  S  +G  L ++  VVR   +        + C  C+ +VI +  +    F    P  C N         A DI +S  +      + Q++ +QE    L  GC+PR+++VIL  + V+  + GD     GT+I                                R    L V D    +L  LA  +Q  N                +IK +M   ++Q  +E    K+      +I+ + P I+G   +K  + L+L G           +RG+ ++ +VGDP TAKSQFLK   + + R+V T+G  S+ AGLT   VK  ES  + +EAGA++LAD G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAG+   L  R SV+AA NP  G YD T+S+  N  +++P++SRFDL F+L+D CNE  D  ++  I++ H   E S E  + +++++ Y  + R  F P +T EA   + + Y  +R+   S  T S  RIT+R LES+IRLS++ AR   ++ V+ +    A  ++  ++    +  +  D++      TD  EE
Sbjct:  108 FIDLPTRHKIRELTSQKIGSLLRISGQVVRTHPVHPELVTATFTCLDCQ-TVIKDVEQQ---FKYTQPTVCRNPICQNRARFALDINKSRYV------DFQKVRIQETQAELPRGCIPRSVEVILRAEAVEQAQAGDKCDFTGTLIVVPDIAQLATPGTRSETGQRQTSGEGYEAEGVRGLKALGVRD-LTYRLSFLACSVQATNPRFGGKDLDGDDMTAEAIKKQMTPQEWQKIYEMSRDKNLYQN--IINSIFPTIHGNDEVKRGVLLMLFGGVPKKTLEKTSLRGDINICVVGDPSTAKSQFLKHVEEFSARAVYTSGKASSAAGLTAAVVKDEESSEFVIEAGAMMLADNGVCCIDEFDKMDPRDQVAIHEAMEQQTISLTKAGVKASLNARTSVLAAANPIGGRYDRTKSLKQNLNMSAPIMSRFDLFFILVDECNEVVDYAIARRIVDLHSRREQSVERVYAVDEVQRYLTFARQ-FKPTITKEAQDYMVEQYKHLRERDGSSTTKSAWRITVRQLESMIRLSEAMARLYCQDKVEPKHVKEAYRLLNKSIIRVETPDIQFDEEGEEDMETDNNEE 675          

Query: 1005 NLLISQMCPLIYGMYFLKLALA-LVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILN-----HQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDR-------ITMRFLESLIRLSQSHARFMMREF-----VKEEDAVMAVAVMESTVYGSTVLSTD 1934
            +++   + P IYG   +K  +A L+  GS     +G+  RG+ ++L++GDPGTAKSQ LKF  K++P  V T+G GS+ AGLT + +++  S  + +E GA+VLADGG+ CIDEF  +RE D+VAIHEAMEQQ+IS+AKAGI   L +RC+V+AA N   G +D T+    N      +LSRFD IF++ D  N++ D  ++  ++       QT ++++   +L  LK Y +Y +S   P+++  A+  L+  Y  MR     +  D        IT+R LE++IR+S+S A+  +  F     V E   +  V+ +++ + GS   ++D
Sbjct:  329 DVIARSIAPSIYGSVDIKKCIACLLFGGSRKRLPDGLTRRGDINVLLLGDPGTAKSQLLKFVEKVSPIGVYTSGKGSSAAGLTASVMRDPVSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCAVLAAANSVFGRWDDTKG-DQNIDFMPTILSRFDTIFIVKDEHNQAKDIHLAKHVMQVHLNAAQTTQANEGELSLSFLKKYISYCKSKCGPRLSESAAEKLKNRYVLMRSGAKEHERDTEKKISIPITVRQLEAIIRISESLAKMSLSPFATETHVDEALRLFQVSTLDAAMSGSLAGASD 658          

Query:  444 VGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTAR--NLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSD---FILNHQTFESSK-ESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRIT-MRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVME 1898
            +GK   V   V+R   ++ +     Y C +C      E  ++  S T  P   C +       +   +   ++ S KF +  QE+ +QE    +  G +PR++ +I   +   L  PGD V + G  +     ++     + Q  +L++     +  +  N +   EM  D  L  E+    S  A   + L S + P IYG   +K AL L+L G  +C  +GMK+RG  ++L++GDPG AKSQ L +  +L PRS  TTG GST  GLT   +K+  +G   LE GALVLAD G+CCIDEF  + + D+ AIHE MEQQ++S+AKAGI+  L  R S++AA NP  G Y+  +S   N  + + LLSRFDL++L+ D  ++  D  ++    ++  H     S  +  ++  ++ Y A  +    P +  E S  +   Y  MRK    N     T  R L +++RL+ + AR  + + V++ED   A+ +ME
Sbjct:  156 IGKLTVVRGIVMRCTEVKPVVEVATYTCDQCG----AESYQTIQSQTFMPLLMCPSEECKTNRAGGRLYLQTRGS-KFVKF-QELKIQEHSDQVPVGHIPRSMTIIAKGENTRLATPGDHVSVTGIFL---PMMKTGFRQMTQ-GLLSDTFLEAHRIVRMNKTEDDEMPTD-DLSDEEIRALSTEADFYDKLASSLAPEIYGHEDIKKALLLLLVGGVDCTPHGMKIRGNINILLMGDPGVAKSQMLSYIDRLAPRSQYTTGRGSTGVGLTAAVMKDPLTGEMILEGGALVLADKGVCCIDEFDKMMDGDRTAIHEVMEQQTVSIAKAGIMTTLNARVSILAAANPAYGRYNPKKSAEQNIQLPAALLSRFDLLWLIQDKPDKENDLRLAQHITYVHQHSAHPPSHYDPLDMNLMRRYIAACKEK-QPIVPGELSDYIVSAYVEMRKDARNNHDTTFTSARTLLAVLRLATALARLRLADVVEKEDVNEAMRLME 638          

Query:  375 QVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKES-FNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYR 1982
              RIT LP C E++R +IP+S DVG FLSV  TV+R    +VLE++R+Y+C KC+  F V  +F   D  +T + P  C +  +GC S  F  + S    P  CR+ QEI +QEQ++ LS G +PR++ VIL+DDLVD  K GDDV I G +  RW  L     C ++LV+ AN ++ VN+  +    + ++ + +F+ FW  Y       RN ++  +CP ++GMY +KLA+A+VL G  +    +G +VRGE HML+VGDPGT KSQFLK+A K+TPRSVLT GIGSTNAGLTV AVK+ G W LEAGALVL+DGG+CCIDEF SI+E D+++IHEAMEQQSISVAKAGIVCKL TR +++AATNPKG YD  + ++ N A+ASPLLSRFDL+ +LLDN N  WD  +S FIL  Q   +   + +++EK+K+YF  I+    P++  +A++IL +YY   R+S+  N+  R T+R LESL RL+++HAR M R+ V  EDAV+AV++ME ++ G  +L     L ++FP DP E+YR
Sbjct:  105 HARITGLPVCPELTRHTIPRSKDVGHFLSVTGTVIRTSVAKVLEYERDYMCTKCRHVFKVHADF---DQFYTFSAPVSCPS-PAGCNSMKFSCL-SEGSEPAACRDYQEIKIQEQVQRLSVGSIPRSLVVILEDDLVDGCKSGDDVTIYGVMCLRWKPLYDGTRCEVELVLRANNLE-VNNQQTAAAQLLTDAQKEFEEFWRSYEHDPMAGRNQILLSLCPQVFGMYVVKLAVAMVLAGGVQRIDPSGTRVRGECHMLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTNAGLTVAAVKDGGEWHLEAGALVLSDGGLCCIDEFNSIKEHDRISIHEAMEQQSISVAKAGIVCKLNTRTTILAATNPKGQYDPNEPLSVNVALASPLLSRFDLVLVLLDNRNAEWDRVISSFILEEQGLPAESSALWSMEKMKAYFCVIKQ-LQPQVCDQANLILTRYYQVQRRSDGRNAA-RTTIRMLESLSRLAEAHARLMFRDTVTIEDAVVAVSIMECSMQGGALLGNVNALLTSFPADPVEQYR 636          

Query:  249 ISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNL--RVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG-MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKE--SGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNH--QTFESSKE-SFNLEK----------------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVM 1895
            ++ +L     +++K+F+   AK +  ++      +  EI    VR+++LP  +EI      + + + + +  +  V     +       +Y C KC F V+  F +S        P  C    S      F++     +     +N Q I +QE    ++ G +PR+   IL  DLVD  KPGD++ + G     ++      N   V   VILAN I   +  ++       ++K    L  ++  G+       + + + P IYG   +K ALAL L G E     G  KVRG+ ++L+ GDPGTAKSQFLK+  K+  R+V TTG G++  GLT    +   S  W+LEAGALVLAD G+C IDEF  + + D+ +IHEAMEQQSIS++KAGIV  L+ RC+V+AA NP  G YD + +   N  +  P++SRFD++ ++ D  +   D  ++ F++    +   S+KE    LE+                L+ Y  Y +   HPK+       + + Y+ +RK  +      IT+R +ES+IR++++HA+  +R++V E+D  MA+ VM
Sbjct:  232 LAYFLPEAPAEMLKVFDEA-AKEVVLAMYPKYDRIAHEI---HVRVSNLPLVEEIRAL---RQLHLNQLIRTSGVVSCCTGVLPQLSMVKYNCSKCSF-VLGPFFQSQNQEV--KPGSCPECQS---QGPFEV----NMEETVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNMANGFPVFATVILANHISRRDEGVAVAELTDEDVKAIVALSKDECIGER------IFASVAPSIYGHEDIKRALALSLFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDADRTSIHEAMEQQSISISKAGIVTSLQARCTVMAAANPIGGRYDPSLTFAENVDLTEPIVSRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSTKEGGVALEEMVLPNTTDVSPIPQDLLRKYIIYAKERVHPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHAKMHLRDYVLEDDVNMAIRVM 782          

Query:  378 VRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI-------------RRWNNLRVND-------------------ECVIQLVILANEIQIVNHTISNNY---------SIKSEMKLDFQLFWEKYHGKSFTARNL---LISQMCPLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFI--LNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLD----RITMRFLESLIRLSQSHARF 1841
            V I  LP   +I   S   S+ +G  + ++  VVR   +        ++C  C+  +     +    F  +PP  C N    C + +   +++ K   KF  + Q++ +QE    L  G +PR+++V+L  + V+  + GD     GT+I             R   + RV                     E   +L  LA  +   N                SIKS+M    +  WEK    S   +NL   L + + P I+G   +K  + L+L G        G  +RG+ ++ IVGDP TAKSQFLK   + +PR+V T+G  ST AGLT   V+  ES  + +EAGAL+LAD G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAG+   L  R S++AA NP  G YD ++S+  N  + +P++SRFDL F+L+D+CNE  D  ++  I  L+ +  ES    ++L++++ Y  + R  F PK++ E+   + + Y  +R+ + T S+     RIT+R LES+IRLS++ AR 
Sbjct:  109 VAIEDLPTRHKIRELS---SMRIGTLVKISCQVVRTHPVHPELVSGTFVCMDCQMVI----KDVPQQFKYSPPTICRN--PVCSNRSRFHLDTHK--SKFI-DFQKVRIQETQAELPRGSIPRSLEVVLRAEAVETAQAGDRCDFTGTLIVVPDVSQLSTPGLRAETSSRVGGGRQGYEAEGLRGLKALGVRELSYRLAFLACNVAPTNPRFGGKELRDEEQTAESIKSQMT---EKEWEKVFEMS-QDKNLYHNLCTSLFPTIHGNDEVKRGILLMLFGGVPKTTMEGTSLRGDVNVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASTAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDIKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVGGRYDRSKSLKQNVNLTAPIMSRFDLFFILVDDCNEVTDYAIARRIVDLHSRVEESVDRLYSLDEIRRYLLFARQ-FKPKISKESEEFIVEQYKRLRQRDSTGSVSKSAWRITVRQLESMIRLSEAMARM 633          

Query:  447 GKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQI--KYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNN---LRVN-DECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTA----------RNLLISQMCPLIYGMYFLKLALALVLCGSENCFF--NGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKES--GGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFES-------------SKESFNLEK------------------------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV 1907
            G+ + V  TVVR  +I+ L  +  + C+ C  ++         +     P  C     GC S +F  + SS L+     + Q I VQE +  +    G +PRT++  L  DL D   PGD VI+ G V  R NN    R N D+C+  L I A  +      +S +   +S   L+ +   E++  K   A            LL+  +CP IYG   +K ALAL L G        N + VRG+ H+LIVGDPG  KSQ L+    + PR +   G  ++  GLTV+  +++  G ++LEAGALVLAD G+CCIDEF  +    + A+ EAMEQQS+S+AKAGIV  L  R SV+AA NP  G+Y+  ++++ N  + S LLSRFD++FLLLD  +ES D C+S+ ++ ++  +              S+ S  L+                         L+ Y +Y R   HP ++PEA+  L+ +Y  +R    +     IT R LESLIRL+++ A+  +RE     DA   V +M+ ++
Sbjct:  221 GRLVCVKGTVVRVSNIRPLCTRMAFRCQTCTSAMSLPLQHGKYAT----PTKC--IQPGCRSRSFAPLRSSALT--LTVDWQIIKVQELMGGEQRETGRIPRTVECHLTSDLCDSCVPGDTVIVTGIV--RVNNDGSSRGNKDQCMFLLYIDATSVSNTKGQLSKSVGEESSGSLEDRSGGEEFSLKELYAVQEIQSQPDLLRLLVHSLCPAIYGHSLVKAALALALFGGRQKHMGKNSVPVRGDPHILIVGDPGLGKSQMLQAVCNVAPRGIYVCGNSTSTTGLTVSLSRDAGTGDYALEAGALVLADQGLCCIDEFDKLGN-QQQALLEAMEQQSVSLAKAGIVSSLPARTSVVAAANPVGGHYNRGKTVSENLKMGSALLSRFDVVFLLLDIPDESHDRCLSEHVMANRAGKGRSSGAVVTRANGESETSILLQHSDMPLSERLQVPAGQTLDLIPACLLRKYISYARQYVHPTLSPEAAQTLQDFYLSLRSQASSADSTPITTRQLESLIRLTEARAKLELREMATRGDAEDVVEIMKHSL 754          

Query:  447 GKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQI--KYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFF--NGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKES--GGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFES-------------SKESFNLEK------------------------LKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV 1907
            G+ + V  TVVR  +I+ L  +  + C+ C  ++         +     P  C     GC S +F  + SS L+     + Q I VQE +  +    G +PRT++  L  DL D   PGD VI+ G V  R NN    D+C+  L I A        ++SN   I  +M +  Q  W       FT         C L+      K ALAL L G        N + VRG+ H+LIVGDPG  KSQ L+    + PR +   G  ++  GLTV+  +++  G ++LEAGALVLAD G+CCIDEF  +    + A+ EAMEQQS+S+AKAGIV  L  R SV+AA NP  G+Y+  ++++ N  + S LLSRFD++FLLLD  +ES D C+S+ ++ ++  +              S+ S  L+                         L+ Y +Y R   HP ++PEA+  L+ +Y  +R    +     IT R LESLIRL+++ A+  +RE     DA   V +M+ ++
Sbjct:  205 GRLVCVKGTVVRVSNIRPLCTRMAFRCQTCTSAMSLPLQHGKYA----TPTKC--IQPGCRSRSFAPLRSSALT--LTVDWQIIKVQELMGGEQRETGRIPRTVECHLTSDLCDSCVPGDTVIVTGIV--RVNNDGNKDQCMFLLYIDAT-------SVSNTKGIVCQMLMQTQ--W------VFT-----FLPFCSLV------KAALALALFGGRQKHMGKNSVPVRGDPHILIVGDPGLGKSQMLQAVCNVAPRGIYVCGNSTSTTGLTVSLSRDAGTGDYALEAGALVLADQGLCCIDEFDKLGN-QQQALLEAMEQQSVSLAKAGIVSSLPARTSVVAAANPVGGHYNRGKTVSENLKMGSALLSRFDVVFLLLDIPDESHDRCLSEHVMANRAGKGRSSGAVVTRANGESETSILLQHSDMPLSERLQVPAGQTLDLIPACLLRKYISYARQYVHPTLSPEAAQTLQDFYLSLRSQASSADSTPITTRQLESLIRLTEARAKLELREMATRGDAEDVVEIMKHSL 698          

Query:   63 MNLLESIEGRHYFLNILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFIPPNNPGIVQDKPFARPPLISKPKRLTALPSVTQKSNTSILNITFNKSILDNFHDVTQIDCSQVNQSXXXXXXXXXXXXXXXAIHSTVSGRLTALPIVSSGRNIFSDSITDTKDLTDDDFEL 2393
            MNLLESIEGRHYFLNILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVILDDDLVDLVKPGDDVIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPLLSRFDLIFLLLDNCNESWDSCVSDFILNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFIPPNNPGIVQDK FARPPLISKPKRLTALPSVTQKSNTSILN TFNKSILDNFHDVTQIDCSQVNQSINIIDEIFNENNNDNAIHSTVSGRLTALPIVSSGRNIFSDSITDTKDLTDDDFEL
Sbjct:    1 MNLLESIEGRHYFLNILTDYLSKNHIQDIQNIINASFKKSINECETLVLRIDVMILLQQYPWISTYLLNNAIKLIKIFNSGFAKLLCSSLNDMGVTLGKEIPNCQVRITSLPFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVILDDDLVDLVKPGDDVIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGNYDITQSITANTAIASPLLSRFDLIFLLLDNCNESWDSCVSDFILNHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFIPPNNPGIVQDKLFARPPLISKPKRLTALPSVTQKSNTSILNSTFNKSILDNFHDVTQIDCSQVNQSINIIDEIFNENNNDNAIHSTVSGRLTALPIVSSGRNIFSDSITDTKDLTDDDFEL 777          

Query:  333 NDMGVTLGKEIPNC--QVRITSL-PFCDEISRTSIPKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCRNRQEINVQE----------------QIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVND------ECVIQLVILANEI----QIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSENCFFNG---MKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKES-GGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFES----------------------------------SKESFN---LEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYG 1913
            N++      ++PN    VRI +  P C  ++     ++  +G F+SV   VV+   ++ +  + ++ C  CK   I    + D  F +  P  C N    C S +F+ ++ S  +     + Q I +QE                     + G +P+T+  IL  DLVD   PGD+VI+ G V+    +   +        C+  LV+  N I      V   + +  S  +E  +      E  H +    + LL++ +CP IYG   +K +L L L G    F N    + +RG SH+LIVGDPG  KSQ L+ A  + PRSV   G   T AGLTV+  K+S  G +LEAGALV++D G CCIDEF  +      ++ EAMEQQSIS+AKAG+VC L  R SV+AA NP  G+Y+  +++  N  +++PLLSRFDL++++LD  NE  DS +S  +L+  T +S                                   KES +    + L+ Y AY +   HPK++ EA+ IL+++Y  +RK         IT R LES++RL+++ AR  +RE   E+DA     +M  ++ G
Sbjct:   79 NNISSISNSDLPNIYINVRIANFSPICKSLNL----QANQIGSFISVKGNVVKVNQVKPVCIRVKFRCLTCKNEQIVVLPD-DYKFAV--PTRCVNRV--CKSKSFEPLKESDETVTI--DYQVIRLQETGSDCPLPFSSNSESIHHDKTNEGRIPKTLNCILIRDLVDNCVPGDEVIVTGIVMTESASTNFHQSSGSGSNCLFNLVLHVNNICRLKGDVKMDVDSENSYDAEFSVKDLYAIEAIHSEPNLFK-LLVASLCPSIYGHELVKASLLLALFGGVTKFGNDKNRVAIRGNSHILIVGDPGLGKSQMLQSACAIAPRSVYICGGSVTTAGLTVSFSKDSDSGTALEAGALVISDNGCCCIDEFDKMSAQQHASLLEAMEQQSISIAKAGMVCNLSARTSVLAAANPNTGHYNKAKTVAENLKMSAPLLSRFDLVYIMLDRPNEVLDSKLSRHVLSLHTEQSLNRSSSSIRQMDTMSFHSMTKEPGSTLHERLSYGHKESCDNIPPQLLRKYIAYAKKYVHPKLSSEAANILQEFYLSLRKRRHFMDGTPITTRQLESMVRLTEAKARSELREIANEQDAKDVKELMLESMMG 664          

Query:  441 DVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINPPKFCSNYSSGCVSS-AFDIVESSKLSPKFCRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVI-------------------------------RRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGK------SFTARNLLISQMC----PLIYGMYFLKLALALVLCGS-ENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVK--ESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNP-KGNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQT----FESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEI---TNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTV 1907
            ++GK +     V+R+  +        + C+ C   V       +  F    P  C N    C++   F+++        F    Q++ VQE    L  GC+PR + VIL ++ V+  +PGD     G++I                                    L V D    ++  LAN +  VN+       +  E +L +    +K   +      +      L+  MC    P  YG   +K  L L+L G        G K+RG+ ++ IVGDP TAKSQFLK     +PR+V T+G  S+ AGLT   V+  ESG + +EAGAL+LA+ G+CCIDEF  +   D+VAIHEAMEQQ+IS+ KAGI   L  + SV+AA NP  G YD ++S+  N ++++P++SRFDL F+L+D C E  D  ++  I   Q      +S    +N + ++ Y  + R  F P++T EA  ++   Y  MR+ +    + S  RIT+R LESL+RLS++ AR    +FV+E D V A  ++  ++
Sbjct:  126 NLGKLVKFRGQVIRSHGVHPELVLGTFKCQDCGTVV----KNIEQQFIFTKPTICGN--PQCMNRLKFELIPEQSKYVDF----QKVRVQETQNELPRGCIPRCMDVILRNETVENAQPGDQSEFTGSLIIIPDISQLTTPGSRTLETKQIKLSEGYDSGVTGLKELGVRD-LTYRMAFLANHVATVNNKYLQTEDMNEEGELTYDSLMKKLTEQEVNKVLTMNQDPNLVKNMCDCLFPTTYGNDEVKRGLLLMLFGGVPKVTEEGTKLRGDINICIVGDPSTAKSQFLKRIAGFSPRAVYTSGKASSAAGLTAAVVRDQESGEFVIEAGALMLANNGVCCIDEFDKMEVRDQVAIHEAMEQQTISLTKAGIKATLNAKTSVLAAANPVGGRYDRSRSLRQNISLSAPIMSRFDLFFVLIDECTEQVDHEIAKRITESQRPVDPEKSDTRIYNEDDIQRYITFARC-FEPRVTEEAFKLMVTEYAKMRERDAASGSRSAWRITVRQLESLVRLSEATARMRFSDFVEECDVVEANRLLSKSI 655          

Query:  432 KSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCKFSVICEFSESDASFTINP-------PKFCSNYSSGCVSSAFDIVESSKLSPKF-------CRNRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIING-TVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSIKSEMKLDFQLFWEKYHGKSFTAR----NLLISQMCPLIYGMYFLKLALA-LVLCGSENCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLTVTAVKESGGWS--LEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPK-GNYDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFILNHQTFESSKESFN----------------LEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMR-------KSEITNSLDRITMRFLESLIRLSQSHARFMMREFVKEEDAVMAVAVMESTVYGSTVLSTDQQLPSAFPTDPEEEYRLLKLNIFKKLQIKSFI 2030
            KS  + K + ++  VV A  I+         CK C+  +         S ++ P       P+ C   +S          +S  + P +       C + Q + +QE  + +  G MPR  ++ +D  L +   PG+ V + G + I + +++ +  + V       + I+++N  I N  S +S +        E+   + F+ +     ++   + P IYG   +K A+A L+  GS      G+ +RG+ +M+++GDPGTAKSQ LKF  +  P +V T+G GS+ AGLT + +++S   S  +E GA+VLADGG+ CIDEF  ++E D+VAIHEAMEQQ+IS+AKAGI   L +RCSV+AA N   G++D T+    N      ++SRFD+IF++ D  +E  D  + + +++    +      N                + KLK Y A+ R    P++TPEA  I+  +Y  MR       K    N+   IT+R LE+++R+++S A+  +  F  E DA  A+ + + +   S+ L+ + +    F TD +E   ++K+   +KL  K F+
Sbjct:  133 KSNQISKLIKISGVVVSASGIKSKAATLTLRCKGCQQYL--------PSVSVKPGLNGYVLPRKCIASASSARFGVGQTAQSCPVDPYYIEPDKCKCNDFQILKLQEAPENVPHGEMPRHSQLFVDRYLCEKAVPGNRVTVVGISSIIQQDSMNMPKDGVKH-----SYIRVLNVEIENTGSTRSGISSLGVTDKEEKEFREFSLKPGVHEIIARSIAPGIYGNPDIKKAIACLLFGGSRKKMPEGVFLRGDINMMMLGDPGTAKSQLLKFVEQCAPIAVYTSGKGSSAAGLTASVIRDSATRSFVMEGGAMVLADGGVVCIDEFDKMKEDDRVAIHEAMEQQTISIAKAGITTMLNSRCSVLAAANSVFGHWDETKG-DENIDFMPTIMSRFDMIFVVKDVYDEKRDKQIVEHVMSVHMGDGQAADVNENISLDSLTAETGIMPVLKLKKYIAFCRDQCGPRLTPEALKIITNHYVSMRSGASEYEKETGKNTSIPITIRQLEAIVRIAESLAKMRLAPFGVEADAREAIRLFQVSTL-SSALTGNLEGVEGF-TDRQEHDVIVKV---EKLMKKRFV 692          

Query:  384 ITSLPFCDEISRTSI---PKSVDVGKFLSVAATVVRAGSIQVLEFQREYICKKCK--FSVICEFSESDASFTINPPKFCSNYSSGCVSSAFDIVESSKLSPKFCR--NRQEINVQEQIKYLSFGCMPRTIKVIXXXXXXXXXXXXXXXIINGTVIRRWNNLRVNDECVIQLVILANEIQIVNHTISNNYSI-KSEMKLDFQLFWE-KYHGKSFTARNLLISQMCPLIYGMYFLKLALALVLCGSE----NCFFNGMKVRGESHMLIVGDPGTAKSQFLKFAHKLTPRSVLTTGIGSTNAGLT--VTAVKESGGWSLEAGALVLADGGICCIDEFTSIRECDKVAIHEAMEQQSISVAKAGIVCKLKTRCSVIAATNPKGN-YDITQSITANTAIASPXXXXXXXXXXXXXNCNESWDSCVSDFIL-----NHQTFESSKESFNLEKLKSYFAYIRSTFHPKMTPEASVILEKYYTWMRKSEITNS-LDRITM--RFLESLIRLSQSHARFMMREFVKEEDAVMA 1883
            I + P+  EISR      P+ +D  + ++V   V+R   I     +  + C  C     V CE         I  P+FC+     C +       + ++    C   ++Q + +QE  + +  G  P T+ +    DLVD ++PGD V + G  I R  + R N +  +   +    + +++   S N  I + E KL  +   E +   +       L   + P IYG   +K  L ++L G           G  +R   H+L+ GDPGT+KSQ L++ + LTPR   T+G GS+  GLT  +T   E+G  +L++GAL L+D GICCIDEF  + +  +  +HE MEQQS+S+AKAGI+C+L  R SV+AA NP G+ +D  ++I  N  +   LLSRFDLIFL+LD  +E +D+ ++  I+     +++T E    + +   L+ Y AY +   HP ++ EA   + + Y  MRK  + N+   +I+   R LESLIRL+++HAR  + + V   D + A
Sbjct:  171 ILTRPYNCEISRNLRNLNPEDLD--QLVTVNGLVIRLSEIIPEMIKAHFKCSVCNNVTKVPCERGR------IIDPEFCNQ----CQAK-----HTQQIVHNCCEFIDKQMVKLQESPEDMPAGETPHTVVLYCYQDLVDTIQPGDRVTVTG--IYRAASQRENSKQRVIKAVFKTYLDVLHFQKSKNRLIDEEEAKLSQERVVEIRALSQKPDLYERLSGAIAPTIYGNETIKKGLLMMLFGGRVKETKKLGAGENMRSNIHVLLCGDPGTSKSQLLQYVYNLTPRGQYTSGKGSSKVGLTAYITKDPETGSSTLQSGALALSDNGICCIDEFDKMTDTTRSVLHEVMEQQSLSIAKAGIICQLHARTSVLAAANPIGSCWDNKKTIIENIQLPPTLLSRFDLIFLILDPQDEQYDAKLARHIVGLYCGHNKTTEPG--TVDTAMLRDYIAYAKENIHPILSEEAENYVTEEYVEMRK--VGNAGKGQISAYPRQLESLIRLAEAHARMRLSDQVTVADCLEA 671