Inositol phosphoceramide mannosyltransferase 3

Overview
NameInositol phosphoceramide mannosyltransferase 3
Smed IDSMED30011483
Length (bp)1135
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Inositol phosphoceramide mannosyltransferase 3 (SMED30011483) t-SNE clustered cells

Violin plots show distribution of expression levels for Inositol phosphoceramide mannosyltransferase 3 (SMED30011483) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Inositol phosphoceramide mannosyltransferase 3 (SMED30011483) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Inositol phosphoceramide mannosyltransferase 3 (SMED30011483) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30011483

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30011483SMESG000054567.1 SMESG000052627.1 dd_Smed_v4_7523_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30011483SMESG000054567.1 SMESG000052627.1 dd_Smed_v4_7523_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30011483SMESG000054567.1 SMESG000052627.1 dd_Smed_v4_7523_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30011483SMESG000054567.1 SMESG000052627.1 dd_Smed_v4_7523_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. UniProt/SwissProt
Match: sp|Q10323|IMT3_SCHPO (Inositol phosphoceramide mannosyltransferase 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC17G8.11c PE=1 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.802e-19
Identity = 54/188 (28.72%), Postives = 91/188 (48.40%), Query Frame = 3
Query:  231 ANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSS------NVLSQTGPIMFTKAFEAYNKLDSNQS 776
            +  IPKIIH  +KT  IP ++    K+C+D++ D ++V W D +   FI  ++  ++  Y SY     ++++ +DV+RYFILYK+GGIY+D D  C +  D  +           H   W+    P    N+ M     H F   ++  L     +       V+  TGP+  +  + A+ KL   ++
Sbjct:   54 SAAIPKIIHQTWKTNEIPEKWVGAQKSCIDLHPDYEYVLWTDESMREFIATDYPWFLTQYDSY----PYNIERADVVRYFILYKYGGIYLDLDVGCNRTLDPLL-----------HYPAWVRRTSPSGISNNVMGFAKGHPFLLQVVRNLPRFAFNYHFPYLTVMYSTGPLFLSIIWSAWRKLPDAEA 226          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. UniProt/SwissProt
Match: sp|Q9UT67|IMT2_SCHPO (Inositol phosphoceramide mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPCC4F11.04c PE=3 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 3.585e-19
Identity = 49/179 (27.37%), Postives = 88/179 (49.16%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSS------NVLSQTGPIMFTKAFEAYNK 758
            IPKIIH  +KT  +P  +    ++C+D++ D +++ W D  +  FI +N+  ++     YF     +++ +DVIRYF+LY +GG Y+D D  C++  D  +           +   W+    P    N  M ++P H +F+ +I  L     S       ++  TGP+  +  +E Y +
Sbjct:   82 IPKIIHQTWKTTEVPEGWKGAQQSCIDLHPDYEYILWTDEMSRNFIADNYPWFL----PYFDAYPFNVQRADVIRYFVLYHYGGNYIDLDDGCRQRLDSLL-----------YYPVWVRRTDPVGVSNDVMGSVPHHPYFELIIQNLEKNAKSYWLPYLTIMLSTGPLSISFLWEKYKR 245          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. UniProt/SwissProt
Match: sp|P33300|SUR1_YEAST (Mannosyl phosphorylinositol ceramide synthase SUR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SUR1 PE=1 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 1.783e-18
Identity = 51/179 (28.49%), Postives = 84/179 (46.93%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADS------SNVLSQTGPIMFTKAFEAYNK 758
            IPKIIH  YKT  IP  +    + C+D++ D K++ W D  AY FI   +  ++  + +Y     + ++ +D IRYFIL  +GG+Y+D D  C++  D  +L     L +            P    N  M ++P H FF   +  L   D         ++  TGP+  +  ++ Y +
Sbjct:   55 IPKIIHQTYKTEDIPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENY----KYPIERADAIRYFILSHYGGVYIDLDDGCERKLD-PLLAFPAFLRKTS----------PLGVSNDVMGSVPRHPFFLKALKSLKHYDKYWFIPYMTIMGSTGPLFLSVIWKQYKR 218          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. UniProt/SwissProt
Match: sp|P38287|CSH1_YEAST (Mannosyl phosphorylinositol ceramide synthase CSH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CSH1 PE=1 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 2.176e-17
Identity = 52/186 (27.96%), Postives = 86/186 (46.24%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSS------NVLSQTGPIMFTKAFEAYNKLDSNQSN 779
            IPKIIH  YKT  IP Q+    + C+D++ D  ++ W D  +  FI   +  ++  + SY     + ++ +D IRYFIL  +GGIY+D D  C++  D  +L     L +            P    N  M ++P H FF  +I  L     +       ++  TGP+  +  ++ Y +  +   N
Sbjct:   62 IPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSY----EYPIERADAIRYFILSHYGGIYIDLDDGCERRLD-PLLKVPAFLRKTS----------PTGVSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKRWSNTAEN 232          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. UniProt/SwissProt
Match: sp|O14084|IMT1_SCHPO (Inositol phosphoceramide mannosyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=imt1 PE=3 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 1.731e-14
Identity = 52/198 (26.26%), Postives = 86/198 (43.43%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDA---KFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLT------MADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILAD 806
            IP++IH ++K   IP ++S  V +C   + D    +F+ W D     F+  N+  ++ ++ SY     ++++  D  RYFILY +GG+YMD D  C+KP D  +   + IL              P    N + AA P H F    I  L+            V    GP+  +  F  Y         V+ +++  +
Sbjct:   64 IPRVIHQLWKDENIPERWSNTVNSCRRQHPDENGWQFILWTDEKIMSFMNENYSWFMPVFHSY----PYNIQKFDAARYFILYHYGGVYMDLDIGCKKPMDPLLSKATFILPS----------TEPIGYSNDWFAATPKHPFLYQAIHNLSKFNHRYFTKYPTVFLSAGPLFLSYQFCKYLLTPHEPVRVLPALLYGN 247          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. TrEMBL
Match: A0A267FEG6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026308g1 PE=4 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 2.124e-38
Identity = 96/321 (29.91%), Postives = 153/321 (47.66%), Query Frame = 3
Query:  102 ITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTM-ADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMK--SVILADPYLYSPLT---KEYLES---RCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGY--DAGKKDIKLNDNVCKIFKN 1031
            +T ++G +   + P +   I  NG+ ++ +                IPKIIH  + T  +   Y P + +C+ +N D ++  W D  A   I + +  ++  Y SY      +L+ +D IRY +L+ FGGIY+D D  CQ+PF  A+      + QE  EQ+ I  ++PY AMNS M + P H F++F+I  ++      N    TGP + T  +  Y  L    SN  K   V L +  + SPL    K++ ++      F+   +   GCK+L              +A+H FLHLGY   AG +  KL  ++ K+F N
Sbjct:   38 MTKIIGHNG--QLPQLDRPILINGIWQMPNYRNSTNSNSTSWSGMSIPKIIHQTFPTKMVYKNYLPLINSCLTLNPDWQYYLWTDSDAEALIASKYPGFLSKYLSY----KDNLERADSIRYIVLHHFGGIYLDMDVECQRPFFPALSGLPAFVDQERQEQSNIFWSMPYSAMNSAMGSAPGHPFYQFMINAMSQYGKVGNAFESTGPRLLTAKYAEYCALSRKASNSAKLPPVALLESRVMSPLMDPGKDWKQTCLVTLNFRWWTVSLAGCKTLQAKNWRMDDSDNATLAVHKFLHLGYRFKAGSRKAKL--DITKVFPN 350          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. TrEMBL
Match: A0A1I8GB54 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017105g1 PE=4 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 3.092e-38
Identity = 96/321 (29.91%), Postives = 153/321 (47.66%), Query Frame = 3
Query:  102 ITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTM-ADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMK--SVILADPYLYSPLT---KEYLES---RCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGY--DAGKKDIKLNDNVCKIFKN 1031
            +T ++G +   + P +   I  NG+ ++ +                IPKIIH  + T  +   Y P + +C+ +N D ++  W D  A   I + +  ++  Y SY      +L+ +D IRY +L+ FGGIY+D D  CQ+PF  A+      + QE  EQ+ I  ++PY AMNS M + P H F++F+I  ++      N    TGP + T  +  Y  L    SN  K   V L +  + SPL    K++ ++      F+   +   GCK+L              +A+H FLHLGY   AG +  KL  ++ K+F N
Sbjct:   38 MTKIIGHNG--QLPQLDRPILINGIWQMPNYRNSTNSNSTSWSNMSIPKIIHQTFPTKMVYKNYLPLINSCLTLNPDWQYYLWTDSDAEALIASKYPGFLSKYLSY----KDNLERADSIRYIVLHHFGGIYLDMDVECQRPFFPALSGLPAFVDQERQEQSNIFWSMPYSAMNSAMGSAPGHPFYQFMINAMSQYGKVGNAFESTGPRLLTAKYAEYCALSRKASNSAKLPPVALLESRVMSPLMDPGKDWKQTCLVTLNFRWWTVSLAGCKTLQAKNWRMDDSDNATLAVHKFLHLGYRFKAGSRKAKL--DITKVFPN 350          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. TrEMBL
Match: A0A1I8HQ23 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 8.143e-38
Identity = 88/267 (32.96%), Postives = 130/267 (48.69%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADS-SNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEY--LESRCKF----------QNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYD--AGKKDI 995
            +PKI+H V+ +  +   Y P V +C+  N D ++  W D TA + I++ +  ++  Y  Y      +L+ +D IRY +L+  GGIY+D D  C +PF  A+      L QE  EQT I     Y AMNS M A P H FF+ +I +L         L  TGP+  T A E+Y ++ +        V L DP ++SPL  +    + RC+               L+++GC  L           G  I +H FLHLGYD  AGK+ +
Sbjct:   64 VPKILHQVFASERVYANYLPFVNSCLSRNPDWQYYLWTDKTAEKLIVDRYPEFLAKYKQY----TDNLEKADSIRYIVLHHMGGIYLDMDVECIRPFFPALEGIQAFLDQERPEQTNIGLAQRYSAMNSAMGARPGHPFFRHVIDQLQAGTRVGEALRTTGPLALTSALESYRRVGA-----AAGVKLLDPKVFSPLMVDMNKWKKRCRGLLLSAKWSSSSRWSLQQRGCVQLQAKGWRADDSNGSTIGLHRFLHLGYDWIAGKQRL 321          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. TrEMBL
Match: A0A267F0E4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012259g1 PE=4 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 4.327e-37
Identity = 90/266 (33.83%), Postives = 133/266 (50.00%), Query Frame = 3
Query:  237 GIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLI--------GKLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEYLESRCKFQNTELKK-KGCKSLSNHRQIQKKKMG-----------EAIAIHLFLHLGY 974
            G+PKIIH+VY+ A +   Y   ++ C+  N D + V W D     F+  +F +++K++ S+     H ++ SD IRY ILYK+GG+YMD D  C  P   ++ + SC L  E   QT  LH   Y AMNS M   P+H FF+ +I         K       ++ S TGP M TK F+ + +  +N + VM +     P + +P +  Y   RCK     L++  G  S S    +Q ++MG             +AIH F HLGY
Sbjct:   83 GVPKIIHFVYRDANVLAPYREALQTCVTKNPDWQVVLWTDQAIKAFMQKHFSSHMKVFESF----PHKIQRSDAIRYLILYKYGGLYMDLDMTCHAPLLPSLASHSCFLDSERRHQTQFLHGRQYSAMNSAMGCTPEHPFFRQVIQFVFRPSTAKRNFLFPVSIFSTTGPEMLTKQFDLWKRDAANPTVVMLNETYFSPKI-NPRSGIY--GRCKSMAPRLQRHSGGLSPSQRVCLQLQQMGFEKSDELFITNRTVAIHQFTHLGY 341          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. TrEMBL
Match: A0A267GJL5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018756g1 PE=4 SV=1)

HSP 1 Score: 145.976 bits (367), Expect = 8.430e-37
Identity = 89/269 (33.09%), Postives = 131/269 (48.70%), Query Frame = 3
Query:  234 NGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADS-SNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKE---------YLESRCKFQNT---ELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYD--AGKKDI 995
            + +PKI+H V+ +  +   Y P V +C+  N D ++  W D TA + I++ +  ++  Y  Y      +L+ +D IRY +L+  GGIY+D D  C +PF  A+      L QE  EQT I     Y AMNS M A P H FF+ +I +L         L  TGP+  T A E+Y      Q      V L DP ++SPL  +         +L    K+ ++    L+++GC  L           G  I +H FLHLGYD  AGK+ +
Sbjct:   62 SSVPKILHQVFASERVYANYLPFVNSCLSRNPDWQYYLWTDKTAEKLIVDRYPEFLAKYKQY----TDNLEKADSIRYIVLHHMGGIYLDMDVECIRPFFPALEGIQAFLDQERPEQTNIGLAQRYSAMNSAMGARPGHPFFRHVIDQLRAGTRVGEALRTTGPLALTSALESY-----RQVRAAADVKLLDPKVFSPLMVDMNKWKKICRHLLLSAKWSSSSRWSLQQRGCVQLQAKGWRADDSNGSTIGLHRFLHLGYDWIAGKQRL 321          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Yeast
Match: SUR1 (Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p; SUR1 has a paralog, CSH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005978])

HSP 1 Score: 89.3521 bits (220), Expect = 2.568e-20
Identity = 51/179 (28.49%), Postives = 84/179 (46.93%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADS------SNVLSQTGPIMFTKAFEAYNK 758
            IPKIIH  YKT  IP  +    + C+D++ D K++ W D  AY FI   +  ++  + +Y     + ++ +D IRYFIL  +GG+Y+D D  C++  D  +L     L +            P    N  M ++P H FF   +  L   D         ++  TGP+  +  ++ Y +
Sbjct:   55 IPKIIHQTYKTEDIPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENY----KYPIERADAIRYFILSHYGGVYIDLDDGCERKLD-PLLAFPAFLRKTS----------PLGVSNDVMGSVPRHPFFLKALKSLKHYDKYWFIPYMTIMGSTGPLFLSVIWKQYKR 218          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Yeast
Match: CSH1 (Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p; CSH1 has a paralog, SUR1, that arose from the whole genome duplication [Source:SGD;Acc:S000000365])

HSP 1 Score: 86.2705 bits (212), Expect = 3.134e-19
Identity = 52/186 (27.96%), Postives = 86/186 (46.24%), Query Frame = 3
Query:  240 IPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSS------NVLSQTGPIMFTKAFEAYNKLDSNQSN 779
            IPKIIH  YKT  IP Q+    + C+D++ D  ++ W D  +  FI   +  ++  + SY     + ++ +D IRYFIL  +GGIY+D D  C++  D  +L     L +            P    N  M ++P H FF  +I  L     +       ++  TGP+  +  ++ Y +  +   N
Sbjct:   62 IPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSY----EYPIERADAIRYFILSHYGGIYIDLDDGCERRLD-PLLKVPAFLRKTS----------PTGVSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKRWSNTAEN 232          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Planmine SMEST
Match: SMESG000054567.1 (SMESG000054567.1)

HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0
Identity = 301/327 (92.05%), Postives = 307/327 (93.88%), Query Frame = 3
Query:   75 MFWIFIVLIITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWATN 1055
            MF  F VLIITS++ ADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYAN IPKIIHYVYKTAFIPTQY PHVKNCM INKDAKFVFW DF AYRFIINNFHNYVKLYSSYFSKSI SLKLSDVIRYF+LYKFGGIYMD DT CQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIP HDFFKFLIGKLTMADSSNVLSQTGP M TKAFEAY KLDS++S V+ SVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKM EAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIW TN
Sbjct:    1 MFCSFTVLIITSILAADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANRIPKIIHYVYKTAFIPTQYFPHVKNCMVINKDAKFVFWTDFVAYRFIINNFHNYVKLYSSYFSKSIESLKLSDVIRYFLLYKFGGIYMDLDTGCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPVHDFFKFLIGKLTMADSSNVLSQTGPFMLTKAFEAYKKLDSDKSKVLDSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMEEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWMTN 327          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Planmine SMEST
Match: SMESG000052627.1 (SMESG000052627.1)

HSP 1 Score: 619.772 bits (1597), Expect = 0.000e+0
Identity = 299/327 (91.44%), Postives = 305/327 (93.27%), Query Frame = 3
Query:   75 MFWIFIVLIITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWATN 1055
            MF  F VLIITS++ ADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYAN IPKIIHYVYKTAFIPTQY PHVKNCM INKDAKFVFW DF AYRFIINNFHNYVKLYSSYFSKSI SLKLSDVIRYF+LYKFGGIYMD DT CQKPFDM MLNGSCILSQEVHEQT ILHNLPYLAMNSFMAAIP HDFFKFLIGKLTMADSSNVLSQTGP M TKAFEAY KLDS++S V+ SVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKM EAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIW TN
Sbjct:    1 MFCSFTVLIITSILAADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANRIPKIIHYVYKTAFIPTQYFPHVKNCMVINKDAKFVFWTDFVAYRFIINNFHNYVKLYSSYFSKSIESLKLSDVIRYFLLYKFGGIYMDLDTGCQKPFDMVMLNGSCILSQEVHEQTLILHNLPYLAMNSFMAAIPVHDFFKFLIGKLTMADSSNVLSQTGPFMLTKAFEAYKKLDSDKSKVLDSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMEEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWMTN 327          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Planmine SMEST
Match: SMESG000054245.1 (SMESG000054245.1)

HSP 1 Score: 550.436 bits (1417), Expect = 0.000e+0
Identity = 261/325 (80.31%), Postives = 287/325 (88.31%), Query Frame = 3
Query:   75 MFWIFIVLIITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWA 1049
            MFWIFIVLIITSV+ ADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHY+YKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKS HSLK+SDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQ  I+ NLPYLAMNSFMAAIPDHDFFK+LIGKLT+ADSS +LSQTGP + + + +AY K+ +N  +V KSV LADPY YSP T+ YLES C+  +   K +GCK L +HRQ QK KM +A+ +HLF+HLGY+  K +IKL DNVC+ F NMTIIWA
Sbjct:    1 MFWIFIVLIITSVLAADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYIYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSTHSLKISDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQKRIMWNLPYLAMNSFMAAIPDHDFFKYLIGKLTLADSSFILSQTGPFLLSNSLDAYKKIVTNTKDVKKSVTLADPYFYSPHTENYLESLCRSPSGFWKIQGCKDLGSHRQQQKLKMNDAVVVHLFMHLGYEFAKGNIKLLDNVCRTFTNMTIIWA 325          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Planmine SMEST
Match: SMESG000054422.1 (SMESG000054422.1)

HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0
Identity = 262/325 (80.62%), Postives = 284/325 (87.38%), Query Frame = 3
Query:   75 MFWIFIVLIITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWA 1049
            MFWIFIVLIITSVM ADSWSKTPIITNTINKNGVCEIFSTN LMEFGRRHQY NGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKS HSLK+SDVIRYFILYKFGGIYMDFDTRCQK FDMAMLNGSCILSQEVHEQT IL NLPYLAMNSFMAAIPDHDFFK+LIGKLT+ADSS +LSQTGP + + + +AY  + +N  +V KSV LADPY YSP T+ YLES C+  +   K +GCK L +HRQ QK KM EA+ +HLF+HLGY+  K +IKL DNVC+ F NMTIIWA
Sbjct:    1 MFWIFIVLIITSVMAADSWSKTPIITNTINKNGVCEIFSTNSLMEFGRRHQYVNGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSTHSLKISDVIRYFILYKFGGIYMDFDTRCQKSFDMAMLNGSCILSQEVHEQTRILWNLPYLAMNSFMAAIPDHDFFKYLIGKLTLADSSFILSQTGPFLLSNSLDAYKNIVTNTKDVKKSVTLADPYFYSPHTENYLESLCRSPSGFWKIQGCKDLGSHRQQQKLKMNEAVVVHLFMHLGYEFAKGNIKLLDNVCRTFTNMTIIWA 325          
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Planmine SMEST
Match: SMESG000052405.1 (SMESG000052405.1)

HSP 1 Score: 548.51 bits (1412), Expect = 0.000e+0
Identity = 263/325 (80.92%), Postives = 286/325 (88.00%), Query Frame = 3
Query:   75 MFWIFIVLIITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIGKLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSPLTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGYDAGKKDIKLNDNVCKIFKNMTIIWA 1049
            MFWIFIVLIITSVM ADSWSKTPIITNTINKNGVCEIFSTN LMEFGRRHQYANGIPKIIHYVYKTA+IPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKS HSLK+SDVIRYFILYKFGGIYMDFDTRCQKPF++AMLNGSCILSQEV EQT IL NLPYLAMNSFMAAIPDHDFFKFLIGKLT+ADSS +LSQTGP + + + +AY K+ +N  +V KSV LADPY YSP T+ YLES CK  +   K +GCK L +HRQ QK KM EA+ +HLF+HLGY+  K +IKL DNVC+ F NMTIIWA
Sbjct:    1 MFWIFIVLIITSVMAADSWSKTPIITNTINKNGVCEIFSTNSLMEFGRRHQYANGIPKIIHYVYKTAYIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSTHSLKISDVIRYFILYKFGGIYMDFDTRCQKPFNIAMLNGSCILSQEVLEQTRILWNLPYLAMNSFMAAIPDHDFFKFLIGKLTLADSSFILSQTGPFLLSNSLDAYKKIITNTKDVKKSVTLADPYFYSPHTENYLESLCKSPSGFWKIQGCKDLGSHRQQQKLKMNEAVVVHLFMHLGYEFAKGNIKLLDNVCRTFTNMTIIWA 325          
The following BLAST results are available for this feature:
BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q10323|IMT3_SCHPO1.802e-1928.72Inositol phosphoceramide mannosyltransferase 3 OS=... [more]
sp|Q9UT67|IMT2_SCHPO3.585e-1927.37Inositol phosphoceramide mannosyltransferase 2 OS=... [more]
sp|P33300|SUR1_YEAST1.783e-1828.49Mannosyl phosphorylinositol ceramide synthase SUR1... [more]
sp|P38287|CSH1_YEAST2.176e-1727.96Mannosyl phosphorylinositol ceramide synthase CSH1... [more]
sp|O14084|IMT1_SCHPO1.731e-1426.26Inositol phosphoceramide mannosyltransferase 1 OS=... [more]
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FEG62.124e-3829.91Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GB543.092e-3829.91Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HQ238.143e-3832.96Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267F0E44.327e-3733.83Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GJL58.430e-3733.09Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SUR12.568e-2028.49Mannosylinositol phosphorylceramide (MIPC) synthas... [more]
CSH13.134e-1927.96Mannosylinositol phosphorylceramide (MIPC) synthas... [more]
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Inositol phosphoceramide mannosyltransferase 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000054567.10.000e+092.05SMESG000054567.1[more]
SMESG000052627.10.000e+091.44SMESG000052627.1[more]
SMESG000054245.10.000e+080.31SMESG000054245.1[more]
SMESG000054422.10.000e+080.62SMESG000054422.1[more]
SMESG000052405.10.000e+080.92SMESG000052405.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30011483 ID=SMED30011483|Name=Inositol phosphoceramide mannosyltransferase 3|organism=Schmidtea mediterranea sexual|type=transcript|length=1135bp
TGGTATACGTGAATTATTGGTAATTATCCATTGTCCATATCATTGATAAT
CGACATTTGCTCACAGACTGAAAAATGTTTTGGATTTTCATCGTGCTTAT
TATCACGTCGGTTATGGGAGCAGATTCGTGGAGTAAAACTCCAATTATTA
CAAATACAATCAATAAAAATGGAGTTTGTGAGATTTTCTCTACCAATTTG
CTGATGGAATTTGGCAGGAGGCATCAATACGCAAACGGAATACCGAAAAT
TATCCATTATGTATACAAAACAGCATTTATTCCTACACAATATTCTCCCC
ATGTCAAGAACTGCATGGACATCAATAAGGATGCAAAATTTGTTTTCTGG
GCGGATTTTACTGCATATCGCTTTATTATCAACAACTTTCACAACTATGT
CAAATTGTACAGTTCTTATTTCTCTAAATCTATACATTCTTTGAAACTAT
CTGACGTGATTCGATATTTCATTTTATATAAATTCGGAGGCATTTATATG
GACTTTGATACCCGATGCCAGAAGCCGTTTGATATGGCAATGTTGAATGG
CAGTTGTATACTCAGTCAAGAAGTCCATGAACAGACGTGGATTCTTCATA
ATTTACCATATTTAGCCATGAATAGTTTCATGGCAGCGATACCGGATCAT
GACTTCTTCAAATTTCTCATAGGGAAATTGACAATGGCTGATTCCTCAAA
TGTTTTGAGTCAAACTGGCCCCATCATGTTCACTAAAGCATTCGAGGCAT
ATAACAAATTAGATTCAAACCAATCAAACGTTATGAAATCTGTAATCTTG
GCAGATCCGTATTTGTATTCGCCTCTCACAAAAGAATATCTTGAAAGTCG
ATGTAAATTTCAAAATACAGAGTTGAAAAAAAAAGGTTGTAAAAGTTTAA
GTAATCATCGACAAATCCAAAAAAAGAAAATGGGAGAGGCAATAGCCATT
CATTTATTCTTGCATCTTGGATACGATGCCGGAAAGAAAGACATCAAACT
GAATGACAATGTCTGCAAAATATTCAAAAATATGACCATAATTTGGGCGA
CAAATTGAACGAGCTGTCATAATACTTTATTTCCAACAATATGTTTTGCT
TTTTTTATTTATTTTATAATATATTATAAACTTAG
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protein sequence of SMED30011483-orf-1

>SMED30011483-orf-1 ID=SMED30011483-orf-1|Name=SMED30011483-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=138bp
MYRFREIRTVQFDIVVKVVDNKAICSKIRPENKFCILIDVHAVLDMGRIL
CRNKCCFVYIMDNFRYSVCVLMPPAKFHQQIGRENLTNSIFIDCICNNWS
FTPRICSHNRRDNKHDENPKHFSVCEQMSIINDMDNG*
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protein sequence of SMED30011483-orf-2

>SMED30011483-orf-2 ID=SMED30011483-orf-2|Name=SMED30011483-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=328bp
MFWIFIVLIITSVMGADSWSKTPIITNTINKNGVCEIFSTNLLMEFGRRH
QYANGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRF
IINNFHNYVKLYSSYFSKSIHSLKLSDVIRYFILYKFGGIYMDFDTRCQK
PFDMAMLNGSCILSQEVHEQTWILHNLPYLAMNSFMAAIPDHDFFKFLIG
KLTMADSSNVLSQTGPIMFTKAFEAYNKLDSNQSNVMKSVILADPYLYSP
LTKEYLESRCKFQNTELKKKGCKSLSNHRQIQKKKMGEAIAIHLFLHLGY
DAGKKDIKLNDNVCKIFKNMTIIWATN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR007577GlycoTrfase_DXD_sugar-bd_CS
IPR029044Nucleotide-diphossugar_trans
Vocabulary: molecular function
TermDefinition
GO:0000030mannosyltransferase activity
GO:0016740transferase activity
GO:0016757transferase activity, transferring glycosyl groups
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0005794Golgi apparatus
GO:0016020membrane
GO:0016021integral component of membrane
GO:0032588trans-Golgi network membrane
GO:0033106cis-Golgi network membrane
Vocabulary: biological process
TermDefinition
GO:0051999mannosyl-inositol phosphorylceramide biosynthetic process
GO:0097502mannosylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007577Glycosyltransferase, DXD sugar-binding motifPFAMPF04488Gly_transf_sugcoord: 77..154
e-value: 5.7E-14
score: 52.5
NoneNo IPR availableGENE3DG3DSA:3.90.550.20coord: 56..301
e-value: 1.8E-14
score: 56.5
NoneNo IPR availablePANTHERPTHR32385FAMILY NOT NAMEDcoord: 51..266
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..15
score: 0.706
IPR029044Nucleotide-diphospho-sugar transferasesSUPERFAMILYSSF53448Nucleotide-diphospho-sugar transferasescoord: 51..236